sujigwak/NVAR huggingface dataset:
UniProt ID: Q95NH6
Variant: G -> E at position 165-165
Variant annotation: in strain: Berkeley
Protein function: Has antimicrobial activity in synergy with other peptides. Strongest activity observed against E.cloacae.
Reference sequence:
MSKIVLLIVVIVGVLGSLAVALPQRPYTQPLIYYPPPPTPPRIYRARRQVLGGSLTSNPSGGADARLDLSKAVGTPDHHVIGQVFAAGNTQTKPVSTPVTSGATLGYNNHGHGLELTKTHTPGVRDSFQQTATANLFNNGVHNLDAKAFASQNQLANGFKFDRNGAALDYSHIKGHGATLTHANIPGLGKQLELGGRANLWQSQDRNTRLDLGSTASKWTSGPFKGQTDLGANLGLSHYFG
UniProt ID: Q95RV2
Variant: K -> N at position 27-27
Variant annotation: in strain: NC350 and NC358
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: S -> T at position 144-144
Variant annotation: in strain: Canton-S
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: W -> C at position 149-149
Variant annotation: in strain: Canton-S
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: S -> T at position 154-154
Variant annotation: in strain: Australia 2, Kenya 38, Kenya 43, Peru and USA 3
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: M -> I at position 198-198
Variant annotation: in strain: Australia 5
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: N -> Y at position 236-236
Variant annotation: in strain: Japan
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95RV2
Variant: Y -> F at position 273-273
Variant annotation: in strain: Australia 5 and USA 1
Protein function: Binds to chromosome ends in a sequence-dependent manner and is required for telomere capping.
Reference sequence:
MLLLLCVNMSGTQMSAFLRKYLADEDKKIRAQFKESDPNNKLILWMHEKTRITEEDLARPYTEDEVKELCLRTKVKVDMTAWNCLWEAKKRFEAKGRFVNKSERFINRMYMKAVRRKMVQPYPEEFVAQRREIVAAETKKQNISRLDRWQKKKSQNLSAPESSPDAHASSNDAVQSHEDQANTNLSSLSQMNFQVEAMAPPGVSSSDLSGIGDDEDEQQQSGFQDENINRPETEINENSVRCDPINLGRMRTGCINSQANNSFRNTESDPDYYMFGTQLSTLVRPTSTQEPDDQVNCPETEMNESWVRCDQINSESLSIGPSIDSEGTITFQNTESEPIDVTSIA
UniProt ID: Q95WC9
Variant: M -> I at position 6-6
Variant annotation: in CsE9
Protein function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
Reference sequence:
MNSLLMITTCLILIGTVLAEDGYLFDKRKRCTLECIDKTGDKNCDRNCKNEGGSFGKCSYFACWCKGLPGITPISRTPGKTCKI
UniProt ID: Q95WC9
Variant: K -> M at position 38-38
Variant annotation: in CsE9
Protein function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
Reference sequence:
MNSLLMITTCLILIGTVLAEDGYLFDKRKRCTLECIDKTGDKNCDRNCKNEGGSFGKCSYFACWCKGLPGITPISRTPGKTCKI
UniProt ID: Q95WC9
Variant: N -> K at position 50-50
Variant annotation: in CsE9
Protein function: Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
Reference sequence:
MNSLLMITTCLILIGTVLAEDGYLFDKRKRCTLECIDKTGDKNCDRNCKNEGGSFGKCSYFACWCKGLPGITPISRTPGKTCKI
UniProt ID: Q96318
Variant: R -> Q at position 170-170
Variant annotation: in strain: cv. Mr-0
Protein function: Seed storage protein.
Reference sequence:
MVKLSNLLVATFGVLLVLNGCLARQSLGVPPQLQNECNLDNLDVLQATETIKSEAGQIEYWDHNHPQLRCVGVSVARYVIEQGGLYLPTFFTSPKISYVVQGTGISGRVVPGCAETFMDSQPMQGQQQGQPWQGRQGQQGQPWEGQGQQGQQGRQGQPWEGQGQQGQQGRQGQQGQPWEGQGQQGQQGFRDMHQKVEHVRRGDVFANTPGSAHWIYNSGEQPLVIIALLDIANYQNQLDRNPRVFHLAGNNQQGGFGGSQQQQEQKNLWSGFDAQVIAQALKIDVQLAQQLQNQQDSRGNIVRVKGPFQVVRPPLRQPYESEEWRHPRSPQGNGLEETICSMRSHENIDDPARADVYKPSLGRVTSVNSYTLPILEYVRLSATRGVLQGNAMVLPKYNMNANEILYCTGGQGRIQVVNDNGQNVLDQQVQKGQLVVIPQGFAYVVQSHGNKFEWISFKTNENAMISTLAGRTSLLRALPLEVISNGFQISPEEARKIKFNTLETTLTRAAGRQQQQLIEEIVEA
UniProt ID: Q964Q7
Variant: F -> Y at position 4-4
Variant annotation: in allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: L -> V at position 10-10
Variant annotation: in allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: I -> F at position 13-13
Variant annotation: in allele CYP6D3v1, allele CYP6D3v3 and allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: V -> A at position 30-30
Variant annotation: in allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: K -> Q at position 74-74
Variant annotation: in allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: E -> D at position 190-190
Variant annotation: in allele CYP6D3v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: Q -> R at position 221-221
Variant annotation: in allele CYP6D3v1, allele CYP6D3v3 and allele CYP6D3v4
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: E -> D at position 339-339
Variant annotation: in allele CYP6D3v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: A -> V at position 344-344
Variant annotation: in allele CYP6D3v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q964Q7
Variant: I -> L at position 363-363
Variant annotation: in allele CYP6D3v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLFLLITLLSAIFIFAKRHYTQWQRLGLVSDEAVIPFGSLAKVFRKERPFGLVMYDLYEKFQEQVVGIYLFFKPALLIRDAELARQILTSDFNSFHDRGIYVDEKNDPMSANLFALEGQSWRTLRMKLTPSFSSGKLKGMFETVDDVGNKLLEYLNNQLKDGQTHVLDIKSILTTYAIDIIGSVIFGLEIDSFTNPDNEFRVLSDRSFDNESRSFLSKLQNLTNFVCPPIAKLLTRLGTKEPVVYRLRDIVKRTIEFREENNVVRKDLLHLLIQLRNTGKISDDNDNLWNKVESTATNLKAMSIDMIASNSFLFYIAGSETTASSTSFTIYELAMNPEALKKAQNEVDECLKKHGIKPDGRITYEAIQDMKYLDLCVKETTRKYPGLPFLNRQCTQDFKVPNSKFTIKKDTNVIISLLGLHRDAKYFPEPLAYKPERFADETKDYDAAAYMPFGEGPRHCIAQRMGVMNTKVALAKILANFNIEPMPHKEAEFQFNTAPVLVPVNGLRVGLSKRSFNRR
UniProt ID: Q96524
Variant: I -> V at position 83-83
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: Q -> S at position 127-127
Variant annotation: in strain: cv. Bu-0, cv. Da(1)-12, cv. Di-G, cv. Landsberg erecta, cv. Le-0, cv. Lip-0, cv. Mrk-0, cv. Stw-0 and cv. Ta-0
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: D -> E at position 326-326
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: V -> M at position 367-367
Variant annotation: in strain: cv. Cvi-0
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: T -> I at position 476-476
Variant annotation: in strain: cv. Cvi-0
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: A -> G at position 482-482
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: A -> S at position 498-498
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: F -> L at position 507-507
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: G -> E at position 511-511
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK
UniProt ID: Q96524
Variant: V -> L at position 543-543
Variant annotation: in strain: cv. Chi-1, cv. Co-1, cv. Kon, cv. PHW-1 and cv. Sha
Protein function: Confers resistance to turnip crinkle virus (TCV) by preventing COP1-mediated proteasome-mediated degradation of RPP8/HRT, thus promoting its stability in light. Exposure to darkness or blue-light induces degradation of CRY2, and in turn of RPP8/HRT, resulting in susceptibility to TCV.
Reference sequence:
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSLAHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLVERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRVIVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTARELLAKAISRTREAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAVRYNGSKRVKPEEEEERDMKKSRGFDERELFSTAESSSSSSVFFVSQSCSLASEGKNLEGIQDSSDQITTSLGKNGCK