sujigwak/NVAR huggingface dataset:
UniProt ID: Q36192
Variant: P -> S at position 57-57
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: I -> M at position 89-89
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: P -> S at position 110-110
Variant annotation: in lineages GB01, GB02, GB03, GB04, GB05, GB08, GB09, GB10, GB12, GB14 and GB17
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: I -> V at position 123-123
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: I -> V at position 153-153
Variant annotation: in lineages GB01, GB02, GB03 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: A -> T at position 236-236
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: T -> A at position 238-238
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: T -> I at position 257-257
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: I -> L at position 303-303
Variant annotation: in lineages GB01, GB02, GB03, GB04 and GB05
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: I -> T at position 368-368
Variant annotation: in lineage GB01
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36192
Variant: N -> S at position 375-375
Variant annotation: in lineages GB10 and GB12
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSFIDLPTPSNISAWWNFGSLLGVCLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVHYGWVIRYVHANGASIFFICLFMHVGRGLYYGSYLFPETWNIGIILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLALTLATLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLVLMPIAGIIENNLLKW
UniProt ID: Q36194
Variant: V -> I at position 356-356
Variant annotation: in strain: Isolate 3
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSLIDLPAPSNISAWWNFGSLLGVCLVLQILTGLFLAMHYTSDTTTAFSSITHICRDVHYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYLLSETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGADLVEWIWGGFSVNKATLTRFFAFHFILPFIILTLAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDALGALLLILVLAALVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLAADLLTLTWIGGQPVEHPFIIIGQLASVLYFTILLVLMPIAGIIENNLSKW
UniProt ID: Q36194
Variant: S -> L at position 377-377
Variant annotation: in strain: Isolate 223
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLAKIINNSLIDLPAPSNISAWWNFGSLLGVCLVLQILTGLFLAMHYTSDTTTAFSSITHICRDVHYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYLLSETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGADLVEWIWGGFSVNKATLTRFFAFHFILPFIILTLAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDALGALLLILVLAALVLFSPDLLGDPDNYIPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLAADLLTLTWIGGQPVEHPFIIIGQLASVLYFTILLVLMPIAGIIENNLSKW
UniProt ID: Q36201
Variant: N -> T at position 15-15
Variant annotation: in strain: Isolate TK 34552 and Isolate TK 34560
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: A -> G at position 152-152
Variant annotation: in strain: Isolate TK 40095, Isolate TK 40403 and Isolate TK 40411
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: V -> G at position 161-161
Variant annotation: in strain: Isolate TK 40114 and Isolate TK 40403
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: D -> H at position 171-171
Variant annotation: in strain: Isolate TK 40043 and Isolate TK 40140
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: T -> A at position 190-190
Variant annotation: in strain: Isolate MVZ 168867, Isolate MVZ 192681, Isolate ROM 104264, Isolate ROM 104368, Isolate ROM 105930, Isolate TK 14522, Isolate TK 17624, Isolate TK 34552, Isolate TK 34555, Isolate TK 34560, Isolate TK 34836, Isolate TK 34842, Isolate TK 34963, Isolate TK 40043, Isolate TK 40082, Isolate TK 40084, Isolate TK 40095, Isolate TK 40099, Isolate TK 40107, Isolate TK 40111, Isolate TK 40114, Isolate TK 40139, Isolate TK 40314, Isolate TK 40318, Isolate TK 40398, Isolate TK 40399, Isolate TK 40401, Isolate TK 40402, Isolate TK 40403, Isolate TK 40406, Isolate TK 40408, Isolate TK 40409, Isolate TK 40410, Isolate TK 40411, Isolate TK 40414, Isolate TK 104603 and Isolate TK 104630
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: F -> I at position 220-220
Variant annotation: in strain: Isolate TK 40140
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: F -> L at position 274-274
Variant annotation: in strain: Isolate ROM 104264
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: F -> L at position 333-333
Variant annotation: in strain: Isolate TK 40403
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36201
Variant: V -> A at position 356-356
Variant annotation: in strain: Isolate TK 40314 and Isolate TK 40318
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSSLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHVSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILILMPAISLTENYLLKW
UniProt ID: Q36324
Variant: L -> V at position 328-328
Variant annotation: in strain: Isolate Bba1
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKSHPLMKIINNTFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTMTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGLYYGSYMFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALATVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALLMIMALLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILILMPMLHTSKQRSMMFRPLSQCLFWVLVADLVTLTWIGGQPVEHPFIIIGQLASILYFSIILVLMPITSIIENSLLKL
UniProt ID: Q36922
Variant: F -> V at position 303-303
Variant annotation: in strain: Isolate TK 44636
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTVIRKKHPLIKIINHSFIDLPAPSNISSWWNFGSLLGLCLIVQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIVLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTVKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSIVILAFMPLLHTSKQRALTFRPITQTMYWILVADLLVLTWIGGQPVEYPFIIIGQTASIAYFTIIVIFMPIAGMIENDIMDLD
UniProt ID: Q36964
Variant: T -> A at position 17-17
Variant annotation: in subspecies Rhodurus
Protein function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
Reference sequence:
FMSPTYLGIPLIAVALTLPWILFPTPSARWLNNRLITLQGWFINRFTQQLLLPLNLGGHKWAALLTSLMLFLITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTAALGHLLPEGTPVPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTSIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQENV
UniProt ID: Q36964
Variant: I -> V at position 136-136
Variant annotation: in subspecies Rhodurus
Protein function: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
Reference sequence:
FMSPTYLGIPLIAVALTLPWILFPTPSARWLNNRLITLQGWFINRFTQQLLLPLNLGGHKWAALLTSLMLFLITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTAALGHLLPEGTPVPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTSIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQENV