sujigwak/NVAR huggingface dataset:
UniProt ID: Q27049
Variant: G -> D at position 95-95
Variant annotation: in clones TR12 and TR28
Protein function: Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. It only minimally suppresses the amidolytic activity of thrombin.
Reference sequence:
MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
UniProt ID: Q27049
Variant: S -> G at position 104-104
Variant annotation: in clones TR12, TR28 and TR45
Protein function: Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. It only minimally suppresses the amidolytic activity of thrombin.
Reference sequence:
MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
UniProt ID: Q27049
Variant: T -> I at position 132-132
Variant annotation: in clones TR12 and TR28
Protein function: Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. It only minimally suppresses the amidolytic activity of thrombin.
Reference sequence:
MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
UniProt ID: Q27049
Variant: L -> F at position 145-145
Variant annotation: in clones TR12, TR28 and TR45
Protein function: Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. It only minimally suppresses the amidolytic activity of thrombin.
Reference sequence:
MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
UniProt ID: Q27049
Variant: K -> N at position 157-157
Variant annotation: in clones TR12, TR28 and TR45
Protein function: Thrombin inhibitor, forms a non-covalent complex with thrombin at a molar ratio of 1:1, inhibits thrombin-induced platelet aggregation, and prolongs thrombin clotting time and activated partial thromboplastin time. It only minimally suppresses the amidolytic activity of thrombin.
Reference sequence:
MKTIIAVTIFGILTCAYAAEGDDCSIEKAMGDFKPEEFFNGTWYLAHGPGVTSPAVCQKFTTSGSKGFTQIVEIGYNKFESNVKFQCNQVDNKNGEQYSFKCKSSDNTEFEADFTFISVSYDNFALVCRSITFTSQPKEDDYLVLERTKSDTDPDAKEIC
UniProt ID: Q27084
Variant: I -> V at position 148-148
Variant annotation: in L10A/B
Protein function: Lectin that binds specifically to N-acetylglucosamine and N-acetylgalactosamine. Is part of the innate immunity host defense system of the horseshoe crab.
Reference sequence:
MKFLLVVLGFIGFLKDGITVGGESMLRGVYQDKFYQGTYPQNKNDNWLARATLIGKGGWSNFKFLFLSPGGELYGVLNDKIYKGTPPTHDNDNWMGRAKKIGNGGWNQFQFLFFDPNGYLYAVSKDKLYKASPPQSDTDNWIARATEIGSGGWSGFKFLFFHPNGYLYAVHGQQFYKALPPVSNQDNWLARATKIGQGGWDTFKFLFFSSVGTLFGVQGGKFYEDYPPSYAHDNWLARAKLIGNGGWDDFRFLFF
UniProt ID: Q27084
Variant: H -> Y at position 232-232
Variant annotation: in L10A/B
Protein function: Lectin that binds specifically to N-acetylglucosamine and N-acetylgalactosamine. Is part of the innate immunity host defense system of the horseshoe crab.
Reference sequence:
MKFLLVVLGFIGFLKDGITVGGESMLRGVYQDKFYQGTYPQNKNDNWLARATLIGKGGWSNFKFLFLSPGGELYGVLNDKIYKGTPPTHDNDNWMGRAKKIGNGGWNQFQFLFFDPNGYLYAVSKDKLYKASPPQSDTDNWIARATEIGSGGWSGFKFLFFHPNGYLYAVHGQQFYKALPPVSNQDNWLARATKIGQGGWDTFKFLFFSSVGTLFGVQGGKFYEDYPPSYAHDNWLARAKLIGNGGWDDFRFLFF
UniProt ID: Q27575
Variant: I -> L at position 45-45
Variant annotation: in strain: S-23
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Reference sequence:
MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP
UniProt ID: Q27575
Variant: I -> V at position 191-191
Variant annotation: in strain: S-23
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Reference sequence:
MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP
UniProt ID: Q27575
Variant: V -> E at position 213-213
Variant annotation: in strain: S-23
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Reference sequence:
MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP
UniProt ID: Q27575
Variant: D -> A at position 241-241
Variant annotation: in strain: S-23
Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Reference sequence:
MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEASRRPRAP
UniProt ID: Q27589
Variant: K -> M at position 163-163
Variant annotation: in strain: CAM-44, CAM-48 and Berkeley
Protein function: Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
Reference sequence:
MLGVVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGKTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSANGVHLGLKPRA
UniProt ID: Q27698
Variant: M -> L at position 55-55
Variant annotation: in allele CYP6D1v3 and allele CYP6D1v5
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: A -> D at position 150-150
Variant annotation: in allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: L -> I at position 153-153
Variant annotation: in allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: S -> T at position 165-165
Variant annotation: in allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: I -> N at position 182-182
Variant annotation: in allele CYP6D1v5
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: Q -> E at position 218-218
Variant annotation: in allele CYP6D1v5 and allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: F -> I at position 220-220
Variant annotation: in allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: NFI -> TFM at position 225-227
Variant annotation: in allele CYP6D1v5 and allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: K -> T at position 262-262
Variant annotation: in allele CYP6D1v5
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: R -> P at position 266-266
Variant annotation: in allele CYP6D1v3
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: D -> N at position 447-447
Variant annotation: in allele CYP6D1v5
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27698
Variant: M -> I at position 469-469
Variant annotation: in allele CYP6D1v4, allele CYP6D1v5 and allele CYP6D1v1
Protein function: Metabolizes pyrethroid insecticides and other xenobiotics.
Reference sequence:
MLLLLLLIVVTTLYIFAKLHYTKWERLGFESDKATIPLGSMAKVFHKERPFGLVMSDIYDKCHEKVVGIYLFFKPALLVRDAELARQILTTDFNSFHDRGLYVDEKNDPMSANLFVMEGQSWRTLRMKLAPSFSSGKLKGMFETVDDVAAKLLNHLNERLKDGQSHVLEIKSILTTYAVDIIGSVIFGLEIDSFTHPDNEFRVLSDRLFNPKKSTMLQRFRNLSNFICPPLAKLLSRLGAKDPITYRLRDIVKRTIEFREEKGVVRKDLLQLFIQLRNTGKISDDNDKLWHDVESTAENLKAMSIDMIASNSFLFYIAGSETTAATTSFTIYELAMYPEILKKAQSEVDECLQRHGLKPQGRLTYEAIQDMKYLDLCVMETTRKYPGLPFLNRKCTQDFQVPDTKLTIPKETGIIISLLGIHRDPQYFPQPEDYRPERFADESKDYDPAAYMPFGEGPRHCIAQRMGVMNSKVALAKILANFNIQPMPRQEVEFKFHSAPVLVPVNGLNVGLSKRW
UniProt ID: Q27756
Variant: A -> V at position 47-47
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: P -> H at position 52-52
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: L -> I at position 82-82
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: PT -> LI at position 92-93
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: P -> S at position 98-98
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: L -> I at position 108-108
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: T -> I at position 289-289
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: G -> S at position 350-350
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: FLGR -> YLSK at position 354-357
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: IIV -> VII at position 395-397
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR
UniProt ID: Q27756
Variant: G -> S at position 401-401
Variant annotation: in 6B3-2
Protein function: Enables the insect to feed on furanocoumarin-producing plants and evolved as an adaptation for detoxification of xanthotoxin and other furanocoumarins.
Reference sequence:
MLYVITLVTVLAGLLHYYFTRNFDYWKKRNVAGPKPIPFFGNLKDSALRRKPQVMVYKSIYDEFPNEKVVGIYRMTTPSVLLRDLDIIKHVPTKDFEPFADRGVEFSLDGLGANIFHADGDRWRSLRNRFTPLFTSGKLKTMLPLMSQVGDKFINTSDEVSQTKSEQSIHDLVQIFTITNIAACAFGLNLDENMLKTLQDLDKYIFTVNYSGEFDMLYPGILKKFNGSIFPKVVKQFFDKLTKDIFEMRKGTSSCQKDMIDSIQELRQQKTVDLWRKHDNEDVKPLELTDGVISAQMFIFYAAGYETSATTMTYLFYELAKNPDIQDKLIAEIDEVLSRHDGNITYECLGEMTFLGRVFDETLRKYPVGDFTQRNAKTDYVFPGTDITIKKGQTIIVSTWGIQNDPKYYPNPEKFDPERFNPENIKNRHPCAYLPFSAGPRNCLGLRFAKWQIEVCVVKVLSKYRVEPSNKSSGEFKFDPMRLFVLPKGGIFVNIVRR