sujigwak/NVAR huggingface dataset:
UniProt ID: Q90597
Variant: K -> E at position 143-143
Variant annotation: in strain: WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: E -> K at position 152-152
Variant annotation: in strain: WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: M -> V at position 158-158
Variant annotation: in strain: WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: S -> T at position 202-202
Variant annotation: in strain: 16, 17
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: I -> V at position 308-308
Variant annotation: in strain: 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: K -> E at position 317-317
Variant annotation: in strain: WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: A -> T at position 339-339
Variant annotation: in strain: 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: H -> R at position 352-352
Variant annotation: in strain: WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: G -> E at position 377-377
Variant annotation: in strain: Black-bone
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: Q -> R at position 505-505
Variant annotation: in strain: Black Minorca and Fayoumi GSP
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: Q -> R at position 530-530
Variant annotation: in strain: Black-bone
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: A -> V at position 548-548
Variant annotation: in strain: 25, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: A -> T at position 583-583
Variant annotation: in strain: 16, 17, 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: S -> N at position 631-631
Variant annotation: in strain: 25, Black-bone, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90VW1
Variant: V -> R at position 80-80
Variant annotation: may be a real difference between the Philippine and Japanese populations
Protein function: Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs) (tested on Torpedo marmorata, Kd=0.07 nM), and with low affinity to neuronal alpha-7/CHRNA7 nAChRs (tested on chimeric alpha-7/CHRNA7, Kd=22 uM) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission . Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site.
Reference sequence:
MKTLLLTLVVVTIVCLDLGYTRICFNHQSSQPQTTKTCSPGESSCYHKQWSDFRGTIIERGCGCPTVKPGIKLSCCESEVCNN
UniProt ID: Q91325
Variant: K -> Q at position 31-31
Protein function: This protein may function to maintain proper structure of myelin.
Reference sequence:
MASATTSDHAKQAGGAHSRQRDSGLLDQLGKLFGQEGSRKVPEKGKEPATRSVLMAPTTHKAHQGARRQTDDSPVVHFFKNMMSPKKAPVQQKAKSGASRAITKFIWGTDGQRAHYGAAGSSKSKDGFRGRKDGSGTLSSFFKMGKKGEGSPARR
UniProt ID: Q91325
Variant: K -> R at position 31-31
Protein function: This protein may function to maintain proper structure of myelin.
Reference sequence:
MASATTSDHAKQAGGAHSRQRDSGLLDQLGKLFGQEGSRKVPEKGKEPATRSVLMAPTTHKAHQGARRQTDDSPVVHFFKNMMSPKKAPVQQKAKSGASRAITKFIWGTDGQRAHYGAAGSSKSKDGFRGRKDGSGTLSSFFKMGKKGEGSPARR
UniProt ID: Q91473
Variant: T -> S at position 87-87
Protein function: Involved in oxygen transport from gills to the various peripheral tissues.
Reference sequence:
MVDWTDAERSAIVGLWGKISVDEIGPQALARLLIVSPWTQRHFSTFGNLSTPAAIMGNPAVAKHGKTVMHGLDRAVQNLDDIKNAYTALSVMHSEKLHVDPDNFRLLADCITVCVAAKLGPTVFSADIQEAFQKFLAVVVSALGRQYH
UniProt ID: Q91473
Variant: T -> A at position 122-122
Protein function: Involved in oxygen transport from gills to the various peripheral tissues.
Reference sequence:
MVDWTDAERSAIVGLWGKISVDEIGPQALARLLIVSPWTQRHFSTFGNLSTPAAIMGNPAVAKHGKTVMHGLDRAVQNLDDIKNAYTALSVMHSEKLHVDPDNFRLLADCITVCVAAKLGPTVFSADIQEAFQKFLAVVVSALGRQYH
UniProt ID: Q91473
Variant: A -> S at position 137-137
Protein function: Involved in oxygen transport from gills to the various peripheral tissues.
Reference sequence:
MVDWTDAERSAIVGLWGKISVDEIGPQALARLLIVSPWTQRHFSTFGNLSTPAAIMGNPAVAKHGKTVMHGLDRAVQNLDDIKNAYTALSVMHSEKLHVDPDNFRLLADCITVCVAAKLGPTVFSADIQEAFQKFLAVVVSALGRQYH
UniProt ID: Q91V16
Variant: D -> G at position 28-28
Protein function: Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB).
Reference sequence:
MANSLRGEVLTLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVEDPEKIKELIARGEFVMKELEALYFLRKYRAMKQRYYSDTKV
UniProt ID: Q91YR1
Variant: Q -> H at position 51-51
Protein function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Reference sequence:
MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVVGSCSPPSDSWEQDYDSFVLPLLEDKQPCYVLFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDEVFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINEVQTDVSVDTKHQTLQGVAFPISRDAFQALEKLSKKQLNYVQLEIDIKNETIILANTENTELRDLPKRIPKDSARYHFFLYKHSHEGDYLESVVFIYSMPGYTCSIRERMLYSSCKSPLLEIVERQLQMDVIRKIEIDNGDELTADFLYDEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAEAEATTD
UniProt ID: Q91ZP3
Variant: G -> R at position 84-84
Variant annotation: in allele FLD2J; causes the fatty liver dystrophy phenotype (fld), characterized by neonatal fatty liver and hypertriglyceridemia that resolve at weaning and neuropathy affecting peripheral nerve in adulthood
Protein function: Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
Reference sequence:
MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGSLQCSPFHVRFGKMGVLRSREKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEIIPMYLATSPILSEGAARMESQLKRNSVDRIRCLDPTTAAQGLPPSDTPSTGSLGKKRRKRRRKAQLDNLKRDDNVNSSEDEDMFPIEMSSDEDTAPMDGSRTLPNDVPPFQDDIPKENFPSISTHPQSASYPSSDREWSPSPSSLVDCQRTPPHLAEGVLSSSCPLQSCHFHASESPSGSRPSTPKSDSELVSKSADRLTPKNNLEMLWLWGELPQAAKSSSPHKMKESSPLGSRKTPDKMNFQAIHSESSDTFSDQSPTMARGLLIHQSKAQTEMQFVNEEDLESLGAAAPPSPVAEELKAPYPNTAQSSSKTDSPSRKKDKRSRHLGADGVYLDDLTDMDPEVAALYFPKNGDPGGLPKQASDNGARSANQSPQSVGGSGIDSGVESTSDSLRDLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFADNPAIIDDPNLVVKVGNKYYNWTTAAPLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNATIKEESKPEQCLTGKGHNTGEQPAQLGLATRIKHESSSSDEEHAAAKPSGSSHLSLLSNVSYKKTLRLTSEQLKSLKLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGKDWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSSLFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRIFTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSCDFPCSDTFSNFTFWREPLPPFENQDMHSASA
UniProt ID: Q91ZR4
Variant: G -> V at position 448-448
Variant annotation: in jck
Protein function: Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia. Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway.
Reference sequence:
MEKYERIRVVGRGAFGIVHLCLRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNIHTDVGSVRMRRAEKSLTPGPPIASGSTGSRATSARCRGVPRGPVRPAIPPPLSSVYAWGGGLSSPLRLPMLNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGTLLPGAVELPQPQFVSRFLEGQSGVTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNLTDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLGTRESHNCPQQVPVAPGQEAQRVVCGIDSSMILTSPGRVLACGSNRFNKLGLDHLSLDEEPVPYQQVEEALSFTPLGSAPLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRVSRAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKGTRGRLGRRDEDAGLPRPVQLDETHPYMVTSVSCCHGNTLLAVRSVTDEPVPP
UniProt ID: Q92093
Variant: I -> T at position 1130-1130
Protein function: Precursor of the major egg-yolk proteins that are sources of nutrients during early development of oviparous organisms.
Reference sequence:
MRAVVLALTLALVASQSVNFAPDFAASKTYVYKYEALLLGGLPEEGLARAGVKVISKVLISAVAENTYLLKLVNPEIFEYSGVWPKDPFVPAAKLTSALAAQFSIPIKFEYAKGVVGKVLAPTAVSETVLNVHRGILNILQLNIKKTQNVYELQEAGAQGVCKTHYVIREDAKAERIHLTKSKDLNNCQQRIMKDFGLAYTEKCVECRQRGEALMGAATYNYLMKPADNGALILEATVTELHQFTPFNEMSGAAQMEAKQMLTFVEIKKDPIIVPDNNYVHRGSIRYEFATEILQMPIQLLKISNARAQAVKILNHLVTYNTAPVHEDAPLKFLQFIQLLRMASSETINAIWAEFKAKPAYRHWILDAVPSIGSSVAVRFIKEKFLAGDITIFEAAQALVAAVHMVAADLETVKLVESLAFNHKIQTHPVLRELTMLGYGTMVSKYCVEHPNCPAELVKPIHELAVQAVANSKFEELSMVLKALGNAGHPASIKPITKLLPVFGTAAAALPLRVQADAVLALRNIAKREPRMVQEVAVQLFMDKALHPELRMLACIVLFETKPPMGLVITLASILKTEKNMQVASFTYSHMMSLTRSTAPDFASVAAACNVAVKMLSNKFRRLSCHFSQAIHLDAYSNPLRIGAAASAFYINDAATLFPRTVVAKARTYFAGAAADVLEVGVRTEGIQEALLKLPPAPENADRITKMRRVIKALSDWRSLATSKPLASIYVKFFGQEIAFANIDKSIIDQALQLANSPSAHALGRNALKALLAGATFQYVKPLLAAEVRRIFPTAVGLPMELSYYTAAVAKAYVNVRATLTPALPETFHAAQLLKTNIELHAEVRPSIVMHTFAVMGVNTAFIQAAIMARAKVRTIVPAKFAAQLDIANGNFKFEAFPVSPPEHIAAAHIETFAVARNVEDVPAERITPLIPAQGVARSTQQSRDKLTSMIADSAASFAGSLSRSSEILYSDLPSNFKPIIKAIVVHLEETICVERLGVKACFEFTSESAAFIRNTLFYNMIGKHSVLISVKPSASEPAIERLEFEVQVGPKAAEKIIKVITMNEEEEAPEGKTVLLKLKKILLPDLKNGTRASSSSSSSSSSSSRSSSSRSRSRKSESSSSSSSSSSRISKRDGPDQPYNPNDRKFKKNHKDSQSTSNVISRSKSSASSFHAIYKQDKFLGNKLAPMVIILFRLVRADHKIEGYQVTAYLNKATSRLQIIMAALDENDNWKLCADGVLLSKHKVTAKIAWGAECKDYNTFITAETGLVGPSPAVRLRLSWDKLPKVPKAVWRYVRIVSEFIPGYIPYYLADLVPMQKDKNNEKQIQFTVVATSERTLDVILKTPKMTLYKLGVNLPCSLPFESMTDLSPFDDNIVNKIHYLFSEVNAVKCSMVRDTLTTFNNKKYKINMPLSCYQVLAQDCTTELKFMVLLKKDHASEQNHINVKISDIDVDLYTEDHGVIVKVNEMEISNDNLPYKDPSGSIKIDRKGKGVSLYAPSHGLQEVYFDKYSWKIKVVDWMKGQTCGLCGKADGENRQEYRTPSGRLTKSSVSFAHSWVLPSDSCRDASECLMKLESVKLEKQVIVDDRESKCYSVEPVLRCLPGCLPVRTTPITIGFHCLPVDSNLNRSEGLSSIYEKSVDLMEKAEAHVACRCSEQCM
UniProt ID: Q920V1
Variant: A -> T at position 4-4
Variant annotation: in strain: NJL/Msf, BLG2/Msf, MSM/Msf and SWN/Msf
Protein function: Transfers N-acetylgalactosamine onto globotriaosylceramide . Plays a critical role in preimplantation stage embryonic development .
Reference sequence:
MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
UniProt ID: Q920V1
Variant: R -> H at position 87-87
Variant annotation: in strain: SWN/Msf
Protein function: Transfers N-acetylgalactosamine onto globotriaosylceramide . Plays a critical role in preimplantation stage embryonic development .
Reference sequence:
MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
UniProt ID: Q920V1
Variant: T -> M at position 128-128
Variant annotation: in strain: CAST/Ei
Protein function: Transfers N-acetylgalactosamine onto globotriaosylceramide . Plays a critical role in preimplantation stage embryonic development .
Reference sequence:
MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
UniProt ID: Q921R4
Variant: L -> P at position 203-203
Variant annotation: in strain: Czech II
Protein function: Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.
Reference sequence:
MAQKHPGERRLCGAHRSGGTSLSTSGSSVDPEILSFSGLRDSAETAPNGTRCLKEHSGPKYTQPPNPAHWSDPSHGPPRGPGPPRGGGYPDESETGSEESGVDQELSRENETGYQEDGSPSFLSIPSACNCQGSPGVPEGTYSEEGDGSSSSLCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPLSRRQKHRFLIKEDVRDSGRREPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRKLKGSDLDLFRVWVGVWARRLGGWARMMFQFLSQSFFCVVGLLIRILRVVGAFLLLALALFLGCLQLGWRFSVGLGNRLGWRDKTAWLFSWLGSPALHHCLTLLKDSRPWQQLVRLIQWGWQELPWVKQRTKKQGNAPVASGRYCQPEEEVTRLLTMAGVPEDELNPFHVLGVEATASDTELKKAYRQLAVMVHPDKNHHPRAEEAFKILRAAWDIVSNPERRKEYEMKRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNRLHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFGSRVPGTSGRQRATPESPPADLQDFLSRIFQVPPGPMSNGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR