sujigwak/NVAR huggingface dataset:
UniProt ID: Q94WW9
Variant: T -> A at position 23-23
Variant annotation: in strain: Isolate 1019
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTRKSHPLIKIMNHSFIDLPTPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWVLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
UniProt ID: Q94WW9
Variant: SL -> GV at position 241-242
Variant annotation: in strain: Isolate 1019
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTRKSHPLIKIMNHSFIDLPTPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWVLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
UniProt ID: Q94WW9
Variant: N -> K at position 255-255
Variant annotation: in strain: Isolate 1019
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTRKSHPLIKIMNHSFIDLPTPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWVLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
UniProt ID: Q94WW9
Variant: V -> M at position 327-327
Variant annotation: in strain: Isolate 1019
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTRKSHPLIKIMNHSFIDLPTPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWVLVANLLILTWIGGQPVEHPFITIGQLASVTYFFTILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: PQ -> RK at position 5-6
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: S -> W at position 31-31
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: L -> I at position 45-45
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: V -> I at position 117-117
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: I -> M at position 218-218
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: L -> M at position 307-307
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94WY6
Variant: N -> Y at position 374-374
Variant annotation: in strain: Isolate I539
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNTPQSHPLIKIVNHSFIDLPAPSNISAWSNFGSLLGVCLGLQLLTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGILFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVTYFFIILILMPSTALMENKLLKW
UniProt ID: Q94Y50
Variant: A -> V at position 238-238
Variant annotation: in strain: Isolate MVZ 152779
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGILLLVLALMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPVLHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPTISLFENKLLKW
UniProt ID: Q94Y50
Variant: T -> I at position 241-241
Variant annotation: in strain: Isolate MVZ 152779
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGILLLVLALMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPVLHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPTISLFENKLLKW
UniProt ID: Q94Y50
Variant: V -> I at position 306-306
Variant annotation: in strain: Isolate MVZ 152779
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGILLLVLALMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILMLFPVLHMSKQRSMMFRPLSQCMFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFMIILLILPTISLFENKLLKW
UniProt ID: Q94YL9
Variant: V -> I at position 364-364
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKSHPLFKLINDALIDLPAPSNISSWWNFGSLLGICLLIQILTGLFLAMHYTSDTTTAFQSVTHICRDVNYGWVLRYLHANGASMFFICLFLHVGRGLYYGSYIYTETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVVVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDMLGALIMILALLLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCMFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILVLMPLVSIVENRLLKW
UniProt ID: Q95046
Variant: S -> N at position 142-142
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: R -> G at position 249-249
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: R -> P at position 457-457
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: A -> P at position 521-521
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: A -> T at position 531-531
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: A -> S at position 534-534
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95046
Variant: L -> F at position 538-538
Variant annotation: in strain: PBOL
Protein function: Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Reference sequence:
MFRSAARFAGKEIRFGTEARQSMQKGVQRAVSAVATTLGPKGRNVIIEQSYGAPKITKDGVTVAKAIEFKDPFENMGAQLVRQVCNKTNDLAGDGTTTSAVLVASVFSESLRCIATGTNPIDMKRGMDRAVGVILQSVAEQSRKVTSTENIVQVATISANGDEELGRLIGQAMEKVGKDGVITTQDGKTMTTELEVVEGMSIDRGYISPYFVTDAKAQKAELEDAFVLVSAKKVSSIHTILPALNHVVRTGRPLLIIADDVESEALTTMIFNKLQGKLKIACVKAPGFGDNKTAMMQDIAIFAGARLVGEEGSGLELDAENFDPAILGTVKKATITKDDTVLLNGGGESSMVKERVELLRGLIDGETSDYNREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALLRASKALDSLLGDSSLTADQRTGVQIIRNAVRLPAHTIVLNAGKEGAVVVEKVLENNDVTVGYDAQRDRYVNMFEAGIIDPARVVRVAITDAVSVASLMMTAEAAIVDLPKEETPAAGGMGGMGGMGGMGDMY
UniProt ID: Q95078
Variant: H -> Y at position 530-530
Variant annotation: in strain: CN15X
Protein function: Probably involved in steroid hormones biosynthesis.
Reference sequence:
MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN
UniProt ID: Q95149
Variant: T -> I at position 47-47
Variant annotation: in subsp. Manitobensis
Protein function: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
Reference sequence:
VALINNQFLPYPYYVKPGAVRSPAQILQWQVLPNTVPAKFCQAQPTTMARHPHPRLSFMAIPPKKNQDKTDIPSINTIATAESTITPTTEAIVDTVATQEASSEVIESAPEAKTDQVTSTVV
UniProt ID: Q95225
Variant: P -> L at position 99-99
Variant annotation: in subsp. Sitkensis
Protein function: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
Reference sequence:
VALINNQFLPYPYYAKPGAVRSPAQILQWQVLPNTVPAKSCQAQPTTLARHPHPRLSFMAIPPKKNQDKTDIPTINTIATVESTITPTTEAIVDTVATPEASSEVIESAPETNTDQVTSTVV
UniProt ID: Q95327
Variant: R -> Q at position 56-56
Protein function: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
Reference sequence:
MLLRLLLLLAPCGAGFATEVVSISLRGNWKIHNGNGSLQLPAAVPGCVHSALFNKRIIKDPYYRFNNLDYRWIALDNWTYIKKFKLHSDMSEWNKVNLVFEGIDTVAVVLLNSVPIGKTDNMFRRYSFDITHMVKAVNIIEVRFQSPVIYANQRSERHTAYWVPPNCPPPVQDGECHVNFIRKMQCSFGWDWGPSFPTQGIWKDVRIEAYNICHLNYFMFTPIYDNYMETWNLKIESSFDVVSSKLVSGEAIVAIPELNIQQRNNIELRHGERTVKLFVKIDKAVIVETWWPHGHGNQTGYDMTVTFELDGGLRFEKSAKVYFRTVELVEEPIQNSPGLTFYFKINGLPIFLKGSNWIPADSFQDRVTSDMLRLLLQSVVDANMNALRVWGGGIYEQDEFYELCDELGIMIWQDFMFACALYPTDEDFMDSVREEVTHQVRRLKSHPSIITWSGNNENEAALMMGWYDTKPGYLHTYIKDYVTLYVKNIRTIVLEGDQTRPFIISSPTNGAKTTAEGWLSPNPYDLNYGDVHFYDYMSDCWNWRTFPKARFVSEYGYQSWPSFSTLEKVSSEEDWSYESSFALHRQHLINGNSEMLQQIELHFKLPNSADQLRRFKDTLYLTQVMQAQCVKTETEFYRRSRNEIVDGKGHTMGALYWQLNDIWQAPSWSSLEYGGKWKMLHYFARRFFAPLLPVGFEDKDVLFIYGVSDLPSDHQMMLTVRVHTWSSLELVCSELTNPFVMKAGESVVLYSKPVPELLKGCPGCTRQSCVVSFYLSTDGELLSPINYHFLSSLKNAKGLHKANITATISQQGNTFVFDLKTSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTVFFYPWKPTSKSELEQSFHVTSLADTY
UniProt ID: Q95327
Variant: T -> S at position 340-340
Protein function: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
Reference sequence:
MLLRLLLLLAPCGAGFATEVVSISLRGNWKIHNGNGSLQLPAAVPGCVHSALFNKRIIKDPYYRFNNLDYRWIALDNWTYIKKFKLHSDMSEWNKVNLVFEGIDTVAVVLLNSVPIGKTDNMFRRYSFDITHMVKAVNIIEVRFQSPVIYANQRSERHTAYWVPPNCPPPVQDGECHVNFIRKMQCSFGWDWGPSFPTQGIWKDVRIEAYNICHLNYFMFTPIYDNYMETWNLKIESSFDVVSSKLVSGEAIVAIPELNIQQRNNIELRHGERTVKLFVKIDKAVIVETWWPHGHGNQTGYDMTVTFELDGGLRFEKSAKVYFRTVELVEEPIQNSPGLTFYFKINGLPIFLKGSNWIPADSFQDRVTSDMLRLLLQSVVDANMNALRVWGGGIYEQDEFYELCDELGIMIWQDFMFACALYPTDEDFMDSVREEVTHQVRRLKSHPSIITWSGNNENEAALMMGWYDTKPGYLHTYIKDYVTLYVKNIRTIVLEGDQTRPFIISSPTNGAKTTAEGWLSPNPYDLNYGDVHFYDYMSDCWNWRTFPKARFVSEYGYQSWPSFSTLEKVSSEEDWSYESSFALHRQHLINGNSEMLQQIELHFKLPNSADQLRRFKDTLYLTQVMQAQCVKTETEFYRRSRNEIVDGKGHTMGALYWQLNDIWQAPSWSSLEYGGKWKMLHYFARRFFAPLLPVGFEDKDVLFIYGVSDLPSDHQMMLTVRVHTWSSLELVCSELTNPFVMKAGESVVLYSKPVPELLKGCPGCTRQSCVVSFYLSTDGELLSPINYHFLSSLKNAKGLHKANITATISQQGNTFVFDLKTSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTVFFYPWKPTSKSELEQSFHVTSLADTY
UniProt ID: Q95723
Variant: I -> V at position 234-234
Variant annotation: in strain: Isolate TK 11240
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTNIRKTHPLLKIINSSFVDLPAPSSLSTWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYMYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLIMLTALATLVLFSPDLLGDPDNYIPANPSITPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHTSKQRSMMFRPLSPCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILLLMPMISMVENYLLKW