sujigwak/NVAR huggingface dataset:
UniProt ID: Q5A8T7
Variant: I -> L at position 2-2
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: K -> R at position 311-311
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: E -> K at position 406-406
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: S -> SESYATTETITTGPLGTDSVIIKEPHNPTVTTTVFWS at position 481-481
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: N -> T at position 492-492
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: E -> L at position 495-495
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: VR -> IK at position 502-503
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: E -> K at position 514-514
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: V -> I at position 526-526
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: K -> R at position 539-539
Variant annotation: in allele ALS5-1
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: H -> Y at position 542-542
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: A -> T at position 1167-1167
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL
UniProt ID: Q5A8T7
Variant: T -> N at position 1202-1202
Variant annotation: in allele ALS5-2
Protein function: Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene.
Reference sequence:
MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPLPNPTTTTTQFWSESFTSTTTITNSLKGTDSVIVREPHNPTVTTTEFWSESYATTETITNGPEGTDSVIVREPHNPTVTTTEFWSESYATTETVTNKPEGTDSVIIKEPHNPTVTTTEFWSESYATTETITTGPLGTDSIVIHDPLEESSSTTAIESSDSNISSSAQESSSSVEQSSSIVGLSSSSDIPLSSDMPSSSSTGLTSSESSTVSSYDSDSSSSSELSTFSSSESYSSSISDTTNFWDSSSSDLESTSITWSSSIDAQSSQSVQSVSNSISTSQETTSSSGEESNTSVTDILVSSDASSILNSDISSYYPSSTISLSDDFPHTIAGEPDSRSSSSIASTVEISSDLVSLTSDPTSSFDSSSSLNSDSSSSPFSDESDISASSSFSTLVAPSFSLSSSSSLSLTYPHYVNSTTYHASESESSSVASPSMASESANDDTHTLSESTDTTSSIGTDSSTVTFCRRDNGDGCIVTGMPSSSIDSEQTSDVTTTSSFVASSTPTSAEQSITDNPNIDSSQTSASSSTKSSVSVSDTVVNSISLSETSTLSSDDSTSSDTSISSTTNSDTGNINAGSSHTSTASIKESSIQKTGVMLSSSYLSTKLSSTSDITTELITTELITTELTTIEDNEPNTFTSTPSSHSEIFSSDNSVLSKQVDRESTIKTSPTTDVTTVSSLSVHSTEASTATLGENSFSNVASTPSNIATSLRSTSSSSNHATESSGTVKSEASAEAIPSPPTSTDNRLSYSTEEAKGITYANSGSTNNLITESQVAAPTDSTSVLIENPVVTSTFDDNSSAAVDQPSKTKSIEESIMNPDSTNETNNGFIATLSQAQVPNSLIHSESISTTMAKTTDASINGDSAASNSQPTTLIQQVATSSYNQPLITTYAGSSSATKHPSWLLKFISVALFFFL