sujigwak/NVAR huggingface dataset:
UniProt ID: Q508K4
Variant: F -> L at position 226-226
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: S -> T at position 241-241
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: V -> I at position 295-295
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: F -> L at position 333-333
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: V -> I at position 353-353
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: F -> L at position 365-365
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: I -> V at position 368-368
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q508K4
Variant: V -> I at position 376-376
Variant annotation: in strain: Isolate LVT 3645
Protein function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Reference sequence:
MTILRKSHPLMKMVNHAFIDLPTPSNISGWWNFGSLLGLCLIIQIASGLFLAMHYTSDTITAFSSVAHICRDVNYGWLIRYIHANGASLFFICLYLHIGRGIYYGSYMYKETWNIGIMLLFLTMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAATAMVHLLFLHETGSNNPLGIPSDSDKIPFHPYYTFKDLLGVIIILASFLSFVLFFPDLLGDPDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPLLHTANQRSMMFRPISQFLFWTLVSDLFILTWIGGQPVEPPFIIIGQVASILYFSIILVFLPIAGLIENKVLKW
UniProt ID: Q51161
Variant: ARH -> VGC at position 2-4
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: F -> L at position 31-31
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: V -> A at position 36-36
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: Q -> R at position 42-42
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: Q -> R at position 50-50
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: S -> P at position 68-68
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: G -> C at position 69-69
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: P -> S at position 84-84
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: I -> V at position 96-96
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: R -> H at position 102-102
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: I -> V at position 105-105
Variant annotation: in strain: 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: N -> T at position 125-125
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: V -> L at position 130-130
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: R -> C at position 135-135
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: A -> T at position 137-137
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: Q -> R at position 147-147
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: K -> E at position 151-151
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15 and 952 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: T -> N at position 152-152
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: A -> T at position 172-172
Variant annotation: in strain: 952 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: S -> A at position 174-174
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15 and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: AECI -> ETCV at position 175-178
Variant annotation: in strain: 952 / Serogroup B /Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: I -> T at position 188-188
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15, 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: G -> C at position 196-196
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: P -> T at position 200-200
Variant annotation: in strain: 952 / Serogroup B / Serotype NT and 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: A -> T at position 206-206
Variant annotation: in strain: 3976 / Serogroup B / Serotype NT
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL
UniProt ID: Q51161
Variant: M -> V at position 208-208
Variant annotation: in strain: BT490 / Serogroup B / Serotype 15
Protein function: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
Reference sequence:
MARHVWQAGRFEIGLDKPKIMGIVNLTPDSFSDGGVYSQNAQTALAHAEQLLKEGADILDIGGESTRSGADYVSPEEEWARVEPVLAEVAGWGVPISLDTRRTVIMEKALALGGIDIINDVAALNDEGAVELLARQADTGICLMHMQGLPKTMQINPKYQDVVGEVARYLKARSAECIAAGIAPQRIILDPGFGSGFGKPLQHNIALMRHLPELMAETGFPLLIGVSRKSTIGELTGEANAAERVHGSVAAALASVARGAQIVRVHDVKATADALKVWEALGINL