sujigwak/NVAR huggingface dataset:
UniProt ID: Q8WZA1
Variant: C -> Y at position 490-490
Variant annotation: in MDDGA3 and MDDGB3; dbSNP:rs267606960
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: P -> R at position 493-493
Variant annotation: in MDDGA3; specific activity abolished; dbSNP:rs28942068
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: G -> A at position 502-502
Variant annotation: in RP76; dbSNP:rs886037948
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: V -> I at position 504-504
Variant annotation: in dbSNP:rs17102066
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: S -> N at position 550-550
Variant annotation: in MDDGA3; dbSNP:rs193919335
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: D -> N at position 556-556
Variant annotation: in MDDGC3; normal enzyme activity but altered kinetic properties; dbSNP:rs74374973
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: R -> P at position 605-605
Variant annotation: in MDDGB3; dbSNP:rs267606962
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZA1
Variant: M -> V at position 623-623
Variant annotation: in dbSNP:rs6659553
Protein function: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins . Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.
Reference sequence:
MDDWKPSPLIKPFGARKKRSWYLTWKYKLTNQRALRRFCQTGAVLFLLVTVIVNIKLILDTRRAISEANEDPEPEQDYDEALGRLEPPRRRGSGPRRVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRMLRSLLSAQGVSPQMITVFIDGYYEEPMDVVALFGLRGIQHTPISIKNARVSQHYKASLTATFNLFPEAKFAVVLEEDLDIAVDFFSFLSQSIHLLEEDDSLYCISAWNDQGYEHTAEDPALLYRVETMPGLGWVLRRSLYKEELEPKWPTPEKLWDWDMWMRMPEQRRGRECIIPDVSRSYHFGIVGLNMNGYFHEAYFKKHKFNTVPGVQLRNVDSLKKEAYEVEVHRLLSEAEVLDHSKNPCEDSFLPDTEGHTYVAFIRMEKDDDFTTWTQLAKCLHIWDLDVRGNHRGLWRLFRKKNHFLMVGVPASPYSVKKPPSVTPIFLEPPPKEEGAPGAPEQT
UniProt ID: Q8WZE0
Variant: T -> S at position 33-33
Variant annotation: in strain: 22000, A128 and Nine
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Reference sequence:
MREIVSLQAGQCGNQIGTKFWEVVSEEHGIDGTGQYTGTSDLQLERINVYYNETGTGKYVPRAVLVDLKPGTMDVIQGGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRKEAEGTDCLQGFQLTHSLGGGTGSGMGTLLVSKIREEFPDRMMATFSVVPSPKVSDTVVEPYNAVLSVHQLVENSDETFCIDNEALYDICFRTLKLSAPTHGDLNGLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFTVGFAPLTARGSSQYRAVTVAELTAQMFDAKNMMAASDPRHGRYLTVAAYFRGKVSMKEVEDQMVSIQQKNSQYFVEWIPNNVQSAHCEVAPRGLKMSVTFIGNNTSIQELFKRVGDHFDVMFRRRAFLHWYTGEGMDEMEFSEASANMHDLIAEYTQYQEAGVDDEEEVAYEEEPQE
UniProt ID: Q8WZE0
Variant: S -> T at position 40-40
Variant annotation: in strain: 22000, A128 and Nine
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Reference sequence:
MREIVSLQAGQCGNQIGTKFWEVVSEEHGIDGTGQYTGTSDLQLERINVYYNETGTGKYVPRAVLVDLKPGTMDVIQGGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRKEAEGTDCLQGFQLTHSLGGGTGSGMGTLLVSKIREEFPDRMMATFSVVPSPKVSDTVVEPYNAVLSVHQLVENSDETFCIDNEALYDICFRTLKLSAPTHGDLNGLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFTVGFAPLTARGSSQYRAVTVAELTAQMFDAKNMMAASDPRHGRYLTVAAYFRGKVSMKEVEDQMVSIQQKNSQYFVEWIPNNVQSAHCEVAPRGLKMSVTFIGNNTSIQELFKRVGDHFDVMFRRRAFLHWYTGEGMDEMEFSEASANMHDLIAEYTQYQEAGVDDEEEVAYEEEPQE
UniProt ID: Q8WZE0
Variant: T -> A at position 54-54
Variant annotation: in strain: 22000, A128 and Nine
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Reference sequence:
MREIVSLQAGQCGNQIGTKFWEVVSEEHGIDGTGQYTGTSDLQLERINVYYNETGTGKYVPRAVLVDLKPGTMDVIQGGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRKEAEGTDCLQGFQLTHSLGGGTGSGMGTLLVSKIREEFPDRMMATFSVVPSPKVSDTVVEPYNAVLSVHQLVENSDETFCIDNEALYDICFRTLKLSAPTHGDLNGLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFTVGFAPLTARGSSQYRAVTVAELTAQMFDAKNMMAASDPRHGRYLTVAAYFRGKVSMKEVEDQMVSIQQKNSQYFVEWIPNNVQSAHCEVAPRGLKMSVTFIGNNTSIQELFKRVGDHFDVMFRRRAFLHWYTGEGMDEMEFSEASANMHDLIAEYTQYQEAGVDDEEEVAYEEEPQE
UniProt ID: Q8WZE0
Variant: K -> E at position 69-69
Variant annotation: in strain: 22000, A128 and Nine
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Reference sequence:
MREIVSLQAGQCGNQIGTKFWEVVSEEHGIDGTGQYTGTSDLQLERINVYYNETGTGKYVPRAVLVDLKPGTMDVIQGGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRKEAEGTDCLQGFQLTHSLGGGTGSGMGTLLVSKIREEFPDRMMATFSVVPSPKVSDTVVEPYNAVLSVHQLVENSDETFCIDNEALYDICFRTLKLSAPTHGDLNGLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFTVGFAPLTARGSSQYRAVTVAELTAQMFDAKNMMAASDPRHGRYLTVAAYFRGKVSMKEVEDQMVSIQQKNSQYFVEWIPNNVQSAHCEVAPRGLKMSVTFIGNNTSIQELFKRVGDHFDVMFRRRAFLHWYTGEGMDEMEFSEASANMHDLIAEYTQYQEAGVDDEEEVAYEEEPQE
UniProt ID: Q8WZE0
Variant: E -> A at position 439-439
Variant annotation: in strain: 22000, A128 and Nine
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Reference sequence:
MREIVSLQAGQCGNQIGTKFWEVVSEEHGIDGTGQYTGTSDLQLERINVYYNETGTGKYVPRAVLVDLKPGTMDVIQGGPLGGLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDQVLDVVRKEAEGTDCLQGFQLTHSLGGGTGSGMGTLLVSKIREEFPDRMMATFSVVPSPKVSDTVVEPYNAVLSVHQLVENSDETFCIDNEALYDICFRTLKLSAPTHGDLNGLVSIVMSGITTCLRFPGQLNSDLRKLAVNMVPFPRLHFFTVGFAPLTARGSSQYRAVTVAELTAQMFDAKNMMAASDPRHGRYLTVAAYFRGKVSMKEVEDQMVSIQQKNSQYFVEWIPNNVQSAHCEVAPRGLKMSVTFIGNNTSIQELFKRVGDHFDVMFRRRAFLHWYTGEGMDEMEFSEASANMHDLIAEYTQYQEAGVDDEEEVAYEEEPQE
UniProt ID: Q8YG56
Variant: I -> T at position 55-55
Variant annotation: in strain: biovar 1
Protein function: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
Reference sequence:
MNIKSLLLGSAAALVAASGAQAADAIVAPEPEAVEYVRVCDAYGAGYFYIPGTEICLRVHGYVRYDVKGGDDVYSGTDRNGWDKGARFALRVSTGSETELGTLKTFTELRFNYAANNSGVDGKYGNETSSGTVMEFAYIQLGGLRVGIDESEFHTFTGYLGDVINDDVISAGSYRTGKISYTFTGGNGFSAVIALEQGGDNDGGYTGTTNYHIDGYMPDVVGGLKYAGGWGSIAGVVAYDSVIEEWAAKVRGDVNITDQFSVWLQGAYSSAATPDQNYGQWGGDWAVWGGLKYQATQKAAFNLQAAHDDWGKTAVTANVAYELVPGFTVTPEVSYTKFGGEWKNTVAEDNAWGGIVRFQRSF
UniProt ID: Q8ZES9
Variant: N -> K at position 504-504
Variant annotation: in strain: KIM5 and 91001
Protein function: Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
Reference sequence:
MEKVWLKRYPADVPAEIDPDRYSSLIEMFENAALRYADQPAFINMGEVMTFRKLEERSRAFAAYLQQGLGLQKGDRVALMMPNLLQYPIALFGVLRAGMIVVNVNPLYTPRELEHQLSDSGAVAIVIVSNFAHTLEKVVFKTQVRHVILTRMGDQLSAAKGTLVNFVVKYIKRLVPKYYLPDAISFRTVLQKGRRMQYVKPDVINTDTAFLQYTGGTTGVAKGAILTHRNMQSNLEQAKAAYAPLLQPGRDLVVTALPLYHIFALTVNCLLFIELGGRSLLITNPRDIPGMVKELSRYPFTAITGVNTLFNALLNNEEFTHLDFSTLRLSVGGGMPVQKAVAEKWETLTGKHLLEGYGLTECSPLVTGNPYDLKHYSGSIGLPVPSTDVRLRDDDGNDVELGKPGELWVRGPQVMLGYWQRPDATDDVLKDGWLATGDIATMDEDGFLRIVDRKKDMILVSGFNVYPNEIEEVVALHAKVLESAVIGVPNEVSGEAVKVFVVKNDASLTPEELLTHCRRYLTGYKVPKIVEFRDELPKSNVGKILRRELRDEEVKVGTTDAA
UniProt ID: Q90597
Variant: W -> R at position 5-5
Variant annotation: in strain: 16, 17, 25, 7, Black Minorca, Fayoumi GSP, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: F -> S at position 8-8
Variant annotation: in strain: Black-bone
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: Q -> R at position 21-21
Variant annotation: in strain: 25, Black Minorca, Fayoumi GSP and WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: R -> P at position 41-41
Variant annotation: in strain: 16, 17, 25, Black Minorca, Fayoumi GSP and WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: S -> L at position 42-42
Variant annotation: in strain: 16, 17, 25, Black Minorca, Fayoumi GSP and WL-F
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: D -> N at position 72-72
Variant annotation: in strain: WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: S -> N at position 84-84
Variant annotation: in strain: WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL
UniProt ID: Q90597
Variant: Q -> R at position 94-94
Variant annotation: in strain: 16, 17, 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N
Protein function: Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus.
Reference sequence:
MNNPWSNFSSAFGCPIQIPKQNSNVPPSLPVPVGVFGVPLRSGCSNQMAFCAPELTDRKPEHEQKVSKRLNDREEDKDEAAACSLDNQYDRKIQPCIDLVDSLRKLDIGNDLMLPAIAVIGDRNSGKSSVLEALSGVALPRDKGVITRCPLELKLKKMTAPQEWKGVIYYRNTEIQLQNASEVKKAIRKAQDIVAGTNGSISGELISLEIWSPDVPDLTLIDLPGIAREAVGNQPQDNGQQIKTLLKKYIGCKETIIVVVVPCNVDIATTEALKMAQEVDPTGERTLGVLTKPDLVNEGTEETVLKIIQNEVIPLRKGYMIVKCYGQMDFCNELSFTSAIQQEREFFETHKHFSTLLDENKATIPHLANKLTDELVGRIIKTLPAIEKQVHDALQQAKKELQKYTQSTHPTVSDKTIFLVGLIKAFNEDISQTMHGKESWFGNEIRLFPKIRREFRTWGVKLLESSAKVEEIVCSKLPKYEDQYRGREFPDFISYWTFEDIIKEQITKLEEPAVAMLNKVIYMVEEKFLQLANKRFANFQNLNNAAQARIGCISDRQATTAKNCILTQFKMERIIYCQDNIYADDLKAARAEGISKDTKIKDLAFGCASRQCPSFALEMVSHVKAYFTGASKRLSNQIPLIILSTVLHDFGNYLQTSMLHLLQGKEEINYLLQEDHEAANQQKLLTSRISHLNKAYQYLVDFKSL