sujigwak/NVAR huggingface dataset:
UniProt ID: Q8VSL2
Variant: F -> S at position 740-740
Variant annotation: in plasmid pWR100 and plasmid pWR501
Protein function: Major protein secreted in laboratory media showing proteolytic activity. May be involved in invasion and destruction of host intestinal epithelium.
Reference sequence:
MNKIYYLKYCHITKSLIAVSELARRVTCKSHRRLSRRVILTSVAALSLSSAWPALSATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKLDKAPMADFSSATITTGSLPPGDHTLYSPQYVVTAKHVSGSDTMSFGYAKNTYTAVGTNNNSGLDIKTRRLSKLVTEVAPAEVSDIGAVSGAYQAGGRFTEFYRLGGGMQYVKDKNGNRTQVYTNGGFLVGGTVSALNSYNNGQMITAQTGDIFNPANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSGTNYGNNWVVTTQDFLGQQPQNDFDKTIAYTSGEGVLQWKYDAANGTGTLTQGNTTWDMHGKKGNDLNAGKNLLFTGNNGEVVLQNSVNQGAGYLQFAGDYRVSALNGQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILNQQADADGKVQAFSSVGIASGRPTVVLSDSQQVNPDNISWGYRGGRLELNGNNLTFTRLQAADYGAIITNNSEKKSTVTLDLQTLKASDINVPVNTVSIFGGRGAPGDLYYDSSTKQYFILKASSYSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIEASSQPYMYHGQLNGNMDVNIPQLSGKDVLALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTTTSSSQSDWETRQFTLEKLKLDAATFHLSRNGKMQGDINATNGSTVILGSSRVFTDRSDGTGNAVFSVEGSATATTVGDQSDYSGNVTLENKSSLQIMERFTGGIEAYDSTVSVTSQNAVFDRVGSFVNSSLTLGKGAKLTAQSGIFSTGAVDVKENASLTLTGMPSAQKQGYYSPVISTTEGINLEDNASFSVKNMGYLSSDIHAGTTAATINLGDSDADAGKTDSPLFSSLMKGYNAVLRGSITGAQSTVNMINALWYSDGKSEAGALKAKGSRIELGDGKHFATLQVKELSADNTTFLMHTNNSRADQLNVTDKLSGSNNSVLVDFLNKPASEMSVTLITAPKGSDEKTFTAGTQQIGFSNVTPVISTEKTDDATKWVLTGYQTTADAGASKAAKDFMASGYKSFLTEVNNLNKRMGDLRDTQGDAGVWARIMNGTGSADGDYSDNYTHVQIGVDRKHELDGVDLFTGALLTYTDSNASSHAFSGKNKSVGGGLYASALFNSGAYFDLIGKYLHHDNQHTANFASLGTKDYSSHSWYAGAEVGYRYHLTKESWVEPQIELVYGSVSGKAFSWEDRGMALSMKDKDYNPLIGRTGVDVGRAFSGDDWKITARAGLGYQFDLLANGETVLQDASGEKRFEGEKDSRMLMTVGMNAEIKDNMRLGLELEKSAFGKYNVDNAINANFRYVF
UniProt ID: Q8VSP9
Variant: R -> K at position 19-19
Variant annotation: in plasmid pWR100, plasmid pWR501 and plasmid pSF5
Protein function: Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of pro-inflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host.
Reference sequence:
MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQSFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
UniProt ID: Q8VSP9
Variant: S -> F at position 66-66
Variant annotation: in plasmid pWR100, plasmid pWR501, plasmid pSF5, plasmid pINV_F6_M1382, plasmid pSf6_579, plasmid pSf3_575, plasmid pSf4a_576, plasmid pSf4b_577 and plasmid pSf5_246
Protein function: Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of pro-inflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host.
Reference sequence:
MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQSFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
UniProt ID: Q8VSR0
Variant: E -> D at position 35-35
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: G -> D at position 40-40
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: I -> V at position 199-199
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: F -> Y at position 218-218
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: D -> E at position 250-250
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: I -> V at position 319-319
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: G -> V at position 373-373
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VSR0
Variant: P -> S at position 523-523
Variant annotation: in strain: AP213
Protein function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
Reference sequence:
MSDKKIKGLEWQEKPLSDNERLKTDSNFLRGTILEDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKIESSDDLLKIEDEPILGKTFLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDDNGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRIPRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
UniProt ID: Q8VWG3
Variant: H -> N at position 201-201
Variant annotation: in strain: cv. Landsberg erecta
Protein function: May act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat . Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development .
Reference sequence:
MESPPLYEISSSSSSEKPRHHFQSLDLFPNLNQNSCINNTLIEPLPLIDRINLNSNLDLNPNPLYAEEGEQEEEEEEEEDREVDVDLHIGLPGFGKPSNDAKQLKKRNGKEIATYDAGKGIENELSGKAYWIPAPEQILIGFTHFSCHVCFKTFNRYNNLQMHMWGHGSQYRKGPESLKGTQPRAMLGIPCYCCVEGCRNHIDHPRSKPLKDFRTLQTHYKRKHGHKPFSCRLCGKLLAVKGDWRTHEKNCGKRWVCVCGSDFKHKRSLKDHVKAFGSGHGPYPTGLFEEQASNSSVSETLFF
UniProt ID: Q8VWG3
Variant: L -> F at position 301-301
Variant annotation: in strain: cv. Landsberg erecta
Protein function: May act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat . Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development .
Reference sequence:
MESPPLYEISSSSSSEKPRHHFQSLDLFPNLNQNSCINNTLIEPLPLIDRINLNSNLDLNPNPLYAEEGEQEEEEEEEEDREVDVDLHIGLPGFGKPSNDAKQLKKRNGKEIATYDAGKGIENELSGKAYWIPAPEQILIGFTHFSCHVCFKTFNRYNNLQMHMWGHGSQYRKGPESLKGTQPRAMLGIPCYCCVEGCRNHIDHPRSKPLKDFRTLQTHYKRKHGHKPFSCRLCGKLLAVKGDWRTHEKNCGKRWVCVCGSDFKHKRSLKDHVKAFGSGHGPYPTGLFEEQASNSSVSETLFF
UniProt ID: Q8VX04
Variant: A -> V at position 67-67
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: L -> I at position 75-75
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: R -> H at position 86-86
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: L -> Q at position 109-109
Variant annotation: in strain: cv. Sorbo
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: D -> G at position 252-252
Variant annotation: in strain: cv. Bl-0, cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Sorbo, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: A -> V at position 450-450
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: M -> L at position 470-470
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: G -> E at position 479-479
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8VX04
Variant: S -> L at position 485-485
Variant annotation: in strain: cv. Ka-0, cv. Lip-0, cv. No-0, cv. Sei-0, cv. Tsu-0 and cv. Wl-0
Protein function: Catalyzes only the first methionine chain elongation cycle.
Reference sequence:
MASSLLTSSGMIPTTGSTVVGRSVLPFQSSLHSLRLTHSYKNPALFISCCSSVSKNAATSSTDLKPAVERWPEYLPNKLPDENYVRVFDTTLRDGEQAPGGSLTPPQKLEIARQLAKLRVDIMEVGFPGSSEEELETVKTIAKTVGNEVDEETGYVPVICAIARSKHRDIEAAWEAVKYAKRPRILIFTSTSDIHMKYKLKKTQEEVIEMAVSSIRFAKSLGFNDIQLGCEDGGRSDKDFLCKILGEAIKADVTVVNVADTVGINMPHEYAELVTYLKANTPGIDDVVFSVHCHNDLGLATANSIAGIRAGARQVEVTINGIGERSGNASLEEVVMALKCRGAYVINGVYTRIDTRQIMATSKMVQEYTGLYVQAHKPIVGANCFVHESGIHQDGILKNRSTYEILSPEDIGIVKSQNSGLVLGKLSGRHAVKDRLKELGYELDDEKLNAVFSLFRDLTKNKKRITDADMKALVTSSDGISLEKSNGANGLKSNGYIPVLQVSSNV
UniProt ID: Q8W468
Variant: D -> E at position 138-138
Variant annotation: in strain: cv. Lisse-2
Protein function: Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
Reference sequence:
MEADDDFYSGTENYSDYADSDEDDADGEYEFVDDAADDSDDLIFRRRQQNYSVLSEADICKLQEDDISRISTVLSISRNSSAILLRHYNWCVSRVHDEWFADEEKVRDAVGLLEKPVVDFPTDGELDCGICFETFLSDKLHAAACGHPFCDSCWEGYITTAINDGPGCLTLRCPDPSCRAAVGQDMINLLAPDKDKQKYTSYFVRSYVEDNRKTKWCPAPGCDYAVNFVVGSGNYDVNCRCCYSFCWNCAEEAHRPVDCDTVSKWVLKNSAESENMNWILANSKPCPKCKRPIEKNQGCMHITCTPPCKFEFCWLCLGAWTEHGEKTGGFYACNRYEAAKQDGIYDETEKRREMAKNSLERYTHYYERWATNQSSRQKALLDLKKMQTDDIEKLSDIQCQPESQLKFIIEAWLQIVECRRVLKWTYAYGFYIPDQEHGKRVFFEYLQGEAESGLERLHQCAEKELLPYLDAKGPSEDFNEFRTKLAGLTSVTKNYFENLVRALENGLSDVNSHDAYDRTSSSKSLGGKTKGSSSKASSSDSSHWPCEYCTYVNPRSTTICQMCEHGR
UniProt ID: Q8W4J9
Variant: IDGQL -> VDEQI at position 27-31
Variant annotation: in strain: cv. Landsberg erecta
Protein function: Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. The interaction with TIP (TCV-interacting protein) may be essential for the recognition of the avirulence proteins, and the triggering of the defense response. Triggers resistance to turnip crinkle virus (TCV) via a SAG101-dependent pathway.
Reference sequence:
MAEAFVSFGLEKLWDLLSRESERLQGIDGQLDGLKRQLRSLQSLLKDADAKKHGSDRVRNFLEDVKDLVFDAEDIIESYVLNKLSGKGKGVKKHVRRLACFLTDRHKVASDIEGITKRISEVIGEMQSFGIQQIIDGGRSLSLQERQRVQREIRQTYPDSSESDLVGVEQSVKELVGHLVENDVHQVVSIAGMGGIGKTTLARQVFHHDLVRRHFDGFAWVCVSQQFTQKHVWQRILQELQPHDGDILQMDEYALQRKLFQLLEAGRYLVVLDDVWKKEDWDVIKAVFPRKRGWKMLLTSRNEGVGIHADPTCLTFRASILNPEESWKLCERIVFPRRDETEVRLDEEMEAMGKEMVTHCGGLPLAVKALGGLLANKHTVPEWKRVFDNIGSQIVGGSWLDDNSLNSVYRILSLSYEDLPTHLKHCFLNLAHFPEDSEISTYSLFYYWAAEGIYDGSTIEDSGEYYLEELVRRNLVIADDNYLSWQSKYCQMHDMMREVCLSKAKEENFLQIIIDPTCTSTINAQSPSRSRRLSIHSGKAFHILGHKNKTKVRSLIVPRFEEDYWIRSASVFHNLTLLRVLDLSWVKFEGGKLPCSIGGLIHLRYLSLYEAKVSHLPSTMRNLKLLLYLNLRVDTEEPIHVPNVLKEMIQLRYLSLPLKMDDKTKLELGDLVNLEYLYGFSTQHSSVTDLLRMTKLRYLAVSLSERCNFETLSSSLRELRNLETLNFLFSLETYMVDYMGEFVLDHFIHLKQLGLAVRMSKIPDQHQFPPHLVHLFLIYCGMEEDPMPILEKLLHLKSVRLARKAFLGSRMVCSKGGFPQLCVIEISKESELEEWIVEEGSMPCLRTLTIDDCKKLKELPDGLKYITSLKELKIEGMKREWKEKLVPGGEDYYKVQHIPDVQFINCDQ
UniProt ID: Q8W4J9
Variant: G -> E at position 29-29
Variant annotation: in strain: cv. Di-17
Protein function: Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. The interaction with TIP (TCV-interacting protein) may be essential for the recognition of the avirulence proteins, and the triggering of the defense response. Triggers resistance to turnip crinkle virus (TCV) via a SAG101-dependent pathway.
Reference sequence:
MAEAFVSFGLEKLWDLLSRESERLQGIDGQLDGLKRQLRSLQSLLKDADAKKHGSDRVRNFLEDVKDLVFDAEDIIESYVLNKLSGKGKGVKKHVRRLACFLTDRHKVASDIEGITKRISEVIGEMQSFGIQQIIDGGRSLSLQERQRVQREIRQTYPDSSESDLVGVEQSVKELVGHLVENDVHQVVSIAGMGGIGKTTLARQVFHHDLVRRHFDGFAWVCVSQQFTQKHVWQRILQELQPHDGDILQMDEYALQRKLFQLLEAGRYLVVLDDVWKKEDWDVIKAVFPRKRGWKMLLTSRNEGVGIHADPTCLTFRASILNPEESWKLCERIVFPRRDETEVRLDEEMEAMGKEMVTHCGGLPLAVKALGGLLANKHTVPEWKRVFDNIGSQIVGGSWLDDNSLNSVYRILSLSYEDLPTHLKHCFLNLAHFPEDSEISTYSLFYYWAAEGIYDGSTIEDSGEYYLEELVRRNLVIADDNYLSWQSKYCQMHDMMREVCLSKAKEENFLQIIIDPTCTSTINAQSPSRSRRLSIHSGKAFHILGHKNKTKVRSLIVPRFEEDYWIRSASVFHNLTLLRVLDLSWVKFEGGKLPCSIGGLIHLRYLSLYEAKVSHLPSTMRNLKLLLYLNLRVDTEEPIHVPNVLKEMIQLRYLSLPLKMDDKTKLELGDLVNLEYLYGFSTQHSSVTDLLRMTKLRYLAVSLSERCNFETLSSSLRELRNLETLNFLFSLETYMVDYMGEFVLDHFIHLKQLGLAVRMSKIPDQHQFPPHLVHLFLIYCGMEEDPMPILEKLLHLKSVRLARKAFLGSRMVCSKGGFPQLCVIEISKESELEEWIVEEGSMPCLRTLTIDDCKKLKELPDGLKYITSLKELKIEGMKREWKEKLVPGGEDYYKVQHIPDVQFINCDQ