sujigwak/NVAR huggingface dataset:
UniProt ID: Q07566
Variant: VNN -> LNK at position 405-407
Variant annotation: in plasmid pINV_F6_M1382
Protein function: Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell.
Reference sequence:
MHITNLGLHQVSFQSGDSYKGAEETGKHKGVSVISYQRVKNGERNKGIEALNRLYLQNQTSLTGKSLLFARDKAEVFCEAIKLAGGDTSKIKAMMERLDTYKLGEVNKRHINELNKVISEEIRAQLGIKNKKELQTKIKQIFTDYLNNKNWGPVNKNISHHGKNYSFQLTPASHMKIGNKNIFVKEYNGKGICCASTRERDHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVSALKGLNSKRGGPTKLLIRNSDGLLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNNKLQKNDNGEPYKLSQRVTLLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYSERIGDPKIWNMVKGYSSFV
UniProt ID: Q07566
Variant: NN -> TK at position 406-407
Variant annotation: in plasmid pCP301
Protein function: Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell.
Reference sequence:
MHITNLGLHQVSFQSGDSYKGAEETGKHKGVSVISYQRVKNGERNKGIEALNRLYLQNQTSLTGKSLLFARDKAEVFCEAIKLAGGDTSKIKAMMERLDTYKLGEVNKRHINELNKVISEEIRAQLGIKNKKELQTKIKQIFTDYLNNKNWGPVNKNISHHGKNYSFQLTPASHMKIGNKNIFVKEYNGKGICCASTRERDHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVSALKGLNSKRGGPTKLLIRNSDGLLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNNKLQKNDNGEPYKLSQRVTLLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYSERIGDPKIWNMVKGYSSFV
UniProt ID: Q07566
Variant: VT -> MA at position 424-425
Variant annotation: in plasmid pINV_F6_M1382
Protein function: Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell.
Reference sequence:
MHITNLGLHQVSFQSGDSYKGAEETGKHKGVSVISYQRVKNGERNKGIEALNRLYLQNQTSLTGKSLLFARDKAEVFCEAIKLAGGDTSKIKAMMERLDTYKLGEVNKRHINELNKVISEEIRAQLGIKNKKELQTKIKQIFTDYLNNKNWGPVNKNISHHGKNYSFQLTPASHMKIGNKNIFVKEYNGKGICCASTRERDHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVSALKGLNSKRGGPTKLLIRNSDGLLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNNKLQKNDNGEPYKLSQRVTLLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYSERIGDPKIWNMVKGYSSFV
UniProt ID: Q07566
Variant: V -> M at position 424-424
Variant annotation: in plasmid pCP301
Protein function: Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell.
Reference sequence:
MHITNLGLHQVSFQSGDSYKGAEETGKHKGVSVISYQRVKNGERNKGIEALNRLYLQNQTSLTGKSLLFARDKAEVFCEAIKLAGGDTSKIKAMMERLDTYKLGEVNKRHINELNKVISEEIRAQLGIKNKKELQTKIKQIFTDYLNNKNWGPVNKNISHHGKNYSFQLTPASHMKIGNKNIFVKEYNGKGICCASTRERDHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVSALKGLNSKRGGPTKLLIRNSDGLLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNNKLQKNDNGEPYKLSQRVTLLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYSERIGDPKIWNMVKGYSSFV
UniProt ID: Q07566
Variant: S -> A at position 519-519
Variant annotation: in plasmid pINV_F6_M1382
Protein function: Converts phosphatidylinositol 4,5-bisphosphate (PtdIns 4,5-P2) to PtdIns 5-P. IpgD is injected by Shigella into the host cell and is required for invasion. The accumulation of PtdIns 5-P causes membrane ruffling and actin cytoskeleton rearrangements at the entry site. Acts in concert with IpaA to coordinate and control the membrane and cytoskeletal rearrangements induced early after invasion of the host cell.
Reference sequence:
MHITNLGLHQVSFQSGDSYKGAEETGKHKGVSVISYQRVKNGERNKGIEALNRLYLQNQTSLTGKSLLFARDKAEVFCEAIKLAGGDTSKIKAMMERLDTYKLGEVNKRHINELNKVISEEIRAQLGIKNKKELQTKIKQIFTDYLNNKNWGPVNKNISHHGKNYSFQLTPASHMKIGNKNIFVKEYNGKGICCASTRERDHIANMWLSKVVDDEGKEIFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVSALKGLNSKRGGPTKLLIRNSDGLLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIYLANQIKEIVNNKLQKNDNGEPYKLSQRVTLLAYTIGAVPCWNCKSGKDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPGNKVMKKLPLSSLELSYSERIGDPKIWNMVKGYSSFV
UniProt ID: Q07609
Variant: N -> T at position 64-64
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: L -> G at position 71-71
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: S -> P at position 90-90
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: I -> N at position 100-100
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: S -> R at position 164-164
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: F -> L at position 174-174
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: A -> G at position 184-184
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: EHR -> KQK at position 212-214
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: E -> K at position 219-219
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07609
Variant: E -> G at position 254-254
Variant annotation: in strain: RM220-3
Protein function: May be a membrane transport protein that could either transport a precursor for rhizopine biosynthesis into bacteroids or the finished product from the bacteroids.
Reference sequence:
MTRTSPRHHAPSETKRRVPMGGVHTNPGKKLTITAVAFQFFINGLVLAAWATSIPHVKNAYSFNDAELGVLLLIMAAGALLFMSLAGYFSHVFGSRRMSIQSALLFPSALVLIFAAPNCMTFLCSIVLFGAANGAMDVLMNHQAKALEENGFPRIMAFLHGCSSTGILAGIMTFGVIGDGHYVARSVTLLTGILIVARWLFPHLLDDVRSGEHRLAIGELRNCKLLMFGILSFLTMVTDGAIAEWSKLYLIRVEQVTDQVGSLGYVAFTLLMIAGRISGDRVKDAIGCRALIAISGSLASAGMTTALFMPSFAGKLAGFALLGLGMANLVPIIFSEAASMNTVSKTVGLTFVSVCGYSGFLVGPPIIGRIAEAVGLGRALLFIIAVGVIVACASVFFDRHRSGQPEP
UniProt ID: Q07627
Variant: PSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFP -> R at position 12-58
Variant annotation: in allele KAP1.6
Protein function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Reference sequence:
MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC
UniProt ID: Q07643
Variant: V -> M at position 525-525
Variant annotation: in strain: C57BL/6
Protein function: Structural component of hyaline cartilage and vitreous of the eye.
Reference sequence:
MTAVPAPRSLFVLLQVLWLALAQIRGPPGEPGPPGPPGPPGVPGSDGIDGDKGPPGKVGPPGSKGEPGKPGPDGPDGKPGIDGLMGAKGEPGPVGTPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGTPGPKGDPGPEGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPAGVKGPQGLQGVKGHPGKRGILGDPGRQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGEMGPRGYKGMVGSIGAAGPPGEEGPRGPPGEAGEKGDVGSQGARGPQGITGPKGITGPPGIDGKDGTPGIPGMKGSAGQVGRPGSPGHQGLAGVPGQPGTKGGPGDKGEPGQQGLPGVSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGIKGDKGSPGKTGPRGGVGDPGVAGLPGEKGEKGQSGEPGLKGQQGVRGETGYPGPSGDIGAPGVQGYPGLPGPRGLVGDRGVPGQPGRQGVVGRAASDQHIVDVVLKMIQEQLAEVAVSAKREALGAAGMVGLPGPPGPPGYPGKQGPNGHPGPRGIPGIVGAVGQIGNTGPKGKRGEKGDRGEMGHGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGRPGPVGLPGFCEPAACLGASAYTSARLTEPGSIKGP
UniProt ID: Q07643
Variant: H -> R at position 610-610
Variant annotation: in strain: C57BL/6
Protein function: Structural component of hyaline cartilage and vitreous of the eye.
Reference sequence:
MTAVPAPRSLFVLLQVLWLALAQIRGPPGEPGPPGPPGPPGVPGSDGIDGDKGPPGKVGPPGSKGEPGKPGPDGPDGKPGIDGLMGAKGEPGPVGTPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGTPGPKGDPGPEGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPAGVKGPQGLQGVKGHPGKRGILGDPGRQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGEMGPRGYKGMVGSIGAAGPPGEEGPRGPPGEAGEKGDVGSQGARGPQGITGPKGITGPPGIDGKDGTPGIPGMKGSAGQVGRPGSPGHQGLAGVPGQPGTKGGPGDKGEPGQQGLPGVSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGIKGDKGSPGKTGPRGGVGDPGVAGLPGEKGEKGQSGEPGLKGQQGVRGETGYPGPSGDIGAPGVQGYPGLPGPRGLVGDRGVPGQPGRQGVVGRAASDQHIVDVVLKMIQEQLAEVAVSAKREALGAAGMVGLPGPPGPPGYPGKQGPNGHPGPRGIPGIVGAVGQIGNTGPKGKRGEKGDRGEMGHGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGRPGPVGLPGFCEPAACLGASAYTSARLTEPGSIKGP
UniProt ID: Q07643
Variant: A -> G at position 666-666
Variant annotation: in strain: C57BL/6
Protein function: Structural component of hyaline cartilage and vitreous of the eye.
Reference sequence:
MTAVPAPRSLFVLLQVLWLALAQIRGPPGEPGPPGPPGPPGVPGSDGIDGDKGPPGKVGPPGSKGEPGKPGPDGPDGKPGIDGLMGAKGEPGPVGTPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGTPGPKGDPGPEGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPAGVKGPQGLQGVKGHPGKRGILGDPGRQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGEMGPRGYKGMVGSIGAAGPPGEEGPRGPPGEAGEKGDVGSQGARGPQGITGPKGITGPPGIDGKDGTPGIPGMKGSAGQVGRPGSPGHQGLAGVPGQPGTKGGPGDKGEPGQQGLPGVSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGIKGDKGSPGKTGPRGGVGDPGVAGLPGEKGEKGQSGEPGLKGQQGVRGETGYPGPSGDIGAPGVQGYPGLPGPRGLVGDRGVPGQPGRQGVVGRAASDQHIVDVVLKMIQEQLAEVAVSAKREALGAAGMVGLPGPPGPPGYPGKQGPNGHPGPRGIPGIVGAVGQIGNTGPKGKRGEKGDRGEMGHGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGRPGPVGLPGFCEPAACLGASAYTSARLTEPGSIKGP
UniProt ID: Q07809
Variant: S -> A at position 38-38
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: A -> E at position 81-81
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: R -> K at position 84-84
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: S -> A at position 87-87
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: A -> T at position 161-161
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: DQAF -> GKGI at position 264-267
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: I -> V at position 273-273
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: S -> N at position 295-295
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: E -> D at position 310-310
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI
UniProt ID: Q07809
Variant: Q -> R at position 316-316
Variant annotation: in strain: ATCC 17587
Protein function: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
Reference sequence:
MDENKKRALAAALGQIEKQFGKGAVMRMGDHDRQAIPSISTGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLTLSVIAAAQRMGSTCAFVDAEHALDPDYAGKLGVNVDDLLVSQPDTGEQALEITDMLVRSNAVDVIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKITGNIKNANCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRTGAVKEGDEVVGSETRVKVVKNKVAPPFRQAEFQILYDQAFYRNGEIIDLGVQQGLVEKSGAWYAYKGSKIGQGKANAAKYLEENPEIGQEIEQQIRAKLLVTSANTKATPVAEDLADADI