'Of course,' she shrugged.
She knew this was going to happen and had little reaction to what had happened, as this was coming for a very long time, and her only words were "Of course,". 
mnli hypothesis: She knew this was going to happen and had little reaction to what had happened, as this was coming for a very long time, and her only words were "Of course,".  premise: 'Of course,' she shrugged.