Yet, in this century, the island has suffered a number of severe setbacks that, until recently, made it a backwater of the Aegean.
The island has suffered a number of severe setbacks, such as a tsunami.
mnli hypothesis: The island has suffered a number of severe setbacks, such as a tsunami. premise: Yet, in this century, the island has suffered a number of severe setbacks that, until recently, made it a backwater of the Aegean.