For example, the Small Business Regulatory Enforcement Fairness Act (SBREFA) requires that EPA and OSHA convene a special review panel before issuing a proposed rule that the agency believes will have a significant economic impact on a substantial number of small entities.
There may be a considerable social impact with the new rule on small entities. 
mnli hypothesis: There may be a considerable social impact with the new rule on small entities.  premise: For example, the Small Business Regulatory Enforcement Fairness Act (SBREFA) requires that EPA and OSHA convene a special review panel before issuing a proposed rule that the agency believes will have a significant economic impact on a substantial number of small entities.