He and his followers conducted a successful series of bloody raids on Spanish settlements in the Caribbean, culminating in the sacking of Panama, the major city of the Spanish Main.
Panama was the most important city of the Spanish Main.
mnli hypothesis: Panama was the most important city of the Spanish Main. premise: He and his followers conducted a successful series of bloody raids on Spanish settlements in the Caribbean, culminating in the sacking of Panama, the major city of the Spanish Main.