Having no near relations or friends, I was trying to make up my mind what to do, when I ran across John Cavendish. 
I came across John Cavendish while I was single and without friends. 
mnli hypothesis: I came across John Cavendish while I was single and without friends.  premise: Having no near relations or friends, I was trying to make up my mind what to do, when I ran across John Cavendish. 