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AIM The aim of this study was to report normative data for the parent-reported Strengths and Difficulties Questionnaire (SDQ) from a large population cohort of young children aged 4-6 years from… (More)
This paper deals with the design of a multi-modal system for pervasive context-aware service provision and human-environment interaction in augmented environments by the use of Personal Digital… (More)
We propose the Agent Network for Bluetooth Devices, a system that uses personal mobile devices as adaptive human-environment interfaces to supply people with ad hoc information and high-level… (More)
The study investigated the use of, attitudes towards, and adherence to motorcycle helmets in a group of adolescents. A random sample of 412 adolescents (14–19 years old) attending randomly selected… (More)
Feature models are used to describe common and variable properties of families of related software systems referred as SPL (Software Product Line). Every program in an SPL is identified by a unique… (More)
In this paper we propose a semantic based image retrieval system in the domain of arctic animals. The proposed system exploits a semantic engine capable of adapting the processing steps both to the… (More)
Examining the relationship between childhood health conditions and health service utilisation at school entry and subsequent academic performance in a large cohort of Australian children.
AIM Chronic health conditions are associated with poor academic outcomes. This study examines the relationship between health conditions, specialist health service utilisation and academic… (More)
DNA double-strand break (DSB)-mediated genome rearrangements are assumed to provide diverse raw genetic materials enabling accelerated adaptive evolution; however, it remains unclear about the… (More)
theory and its applications to business and management have become an active research area in recent two decades. There is a shift from traditional mechanistic worldview towards emerging worldview,… (More)
Information transfer and knowledge sharing beyond one's organizational boundary in an extended enterprise model will be an inevitable trend forced by the global scale competition. This paper focuses… (More)
This work presents a conceptual framework of business risk management for small & medium enterprises (SME) investing in China from a Singaporean perspective, drawing essence from the concepts on risk… (More)
Utilizing secondary data, this paper analyzes the mutual-choice social networks for single-loop and double-loop knowledge benefits. Two interesting results are presented. First, we observe that… (More)
The aim of the present study was to study spawning stimulation in artificial reproduction of females pikeperch (Sander lucioperca L.) using “Chorulon” containing the human chorionic gonadotropin… (More)
Macroscopically visible lipid deposition varying in size from pinpoint to 8-mm diameter was found in spleens of a population of intensively farmed perch, Perca fluviatilis L. over a 24-month rearing… (More)
Sensory attributes, texture and fatty acid profiles of fillets of Eurasian perch (Percafluviatilis L.) reared under two conditions were compared. Perch were reared either in an extensive pond-based… (More)
The effect of fish size and stocking density on the weaning success of pond-cultured pikeperch Sander lucioperca L. juveniles
The effect of initial fish size (small with TL = 40.3 ± 2.3 mm and W = 0.42 ± 0.15 g, medium with TL = 56.2 ± 2.7 mm and W = 1.66 ± 0.4 g, and big with TL = 71.0 ± 3.2 mm and W = 2.95 ± 0.65 g) and… (More)
Comparison of production efficiency and quality of differently cultured pikeperch (Sander lucioperca L.) juveniles as a valuable product for ongrowing culture
Production efficiency, frequency of fin erosion, skeletal and gill covers deformities, proximal composition of fish body with special emphasis on fatty acid contents in liver and muscle, oxidative… (More)
Dynamics of ATP and movement in Eurasian perch (Perca fluviatilis L.) sperm in conditions of decreasing osmolality.
Repetitive activation of perch (Perca fluviatilis L.) sperm motility was investigated in this study. The first phase of sperm motility activation was initiated by dilution in a 260 mM glucose… (More)
A population of Turkestan sculpin Cottus spinulosus Kessler, 1872 was discovered in the Talas River watershed in Kazakhstan in April 2012, and sampled in July and October 2013. The dorsal head and… (More)
Prevalence of deformities in intensively reared peled Coregonus peled and comparative morphometry with pond-reared fish.
Influence of nitrite on two fish species, Eurasian perch (Perca fluviatilis L.) and largemouth bass (Micropterus salmoides Lacépède), was assessed in two acute toxicity tests. In the first one,… (More)
Numerous cross-sectional MRI studies have characterized age-related differences in regional brain volumes that differ with structure and tissue type. The extent to which cross-sectional assumptions… (More)
Neurodevelopment continues through adolescence, with notable maturation of white matter tracts comprising regional fiber systems progressing at different rates. To identify factors that could… (More)
Accelerated aging of selective brain structures in human immunodeficiency virus infection: a controlled, longitudinal magnetic resonance imaging study.
Advances in treatment have transformed human immunodeficiency virus (HIV) infection from an inexorable march to severe morbidity and premature death to a manageable chronic condition, often marked by… (More)
White matter microstructural recovery with abstinence and decline with relapse in alcohol dependence interacts with normal ageing: a controlled longitudinal DTI study.
OBJECTIVE During adolescence, neurobiological maturation occurs concurrently with social and interpersonal changes, including the initiation of alcohol and other substance use. The National… (More)
The transition from adolescent to adult cognition and emotional control requires neurodevelopmental maturation likely involving intrinsic functional networks (IFNs). Normal neurodevelopment may be… (More)
C2C12 myotubes inhibit the proliferation and differentiation of 3T3-L1 preadipocytes by reducing the expression of glucocorticoid receptor gene.
Obesity is a well-established risk factor to health for its relationship with insulin resistance, diabetes and metabolic syndrome. Myocyte-adipocyte crosstalk model plays a significant role in… (More)
Statins are HMG-CoA reductase inhibitors that are used to decrease the blood levels of low-density lipoprotein (LDL). In addition, they have been shown to exert pleiotropic protective effects in the… (More)
OBJECTIVE The authors sought evidence for altered adolescent brain growth trajectory associated with moderate and heavy alcohol use in a large national, multisite, prospective study of adolescents… (More)
This experiment aimed to investigate the relieving action of Artemisia argyi aqueous extract (AAE) on immune stress in broiler chickens. A 2 × 2 factorial design was used to test the effect of 2… (More)
The present study addressed the problem of speaker adaptation in both feature-based and stochastic model-based continuous speech recognition systems. Effective speaker adaptation procedures must be… (More)
Modified matched spatial filters capable of recognition and discrimination are described. Synthesis of these filters in the frequency rather than the space domain is considered. Synthesis of a… (More)
We observe off-axis phase-matched terahertz generation in long air-plasma filaments produced by femtosecond two-color laser focusing. Here, phase matching naturally occurs due to off-axis… (More)
Two-dimensional (2-D) transverse photocurrent generation is studied and applied to control and optimize terahertz energy and polarization in two-color, laser-produced air filaments. A full control of… (More)
Solid-state high-harmonic sources offer the possibility of compact, high-repetition-rate attosecond light emitters. However, the time structure of high harmonics must be characterized at the… (More)
High-harmonic generation in isolated atoms and molecules has been widely utilized in extreme ultraviolet photonics and attosecond pulse metrology. Recently, high-harmonic generation has been observed… (More)
We observe terahertz polarization evolves from linear to elliptical with increasing plasma length. This ellipticity arises from successive polarization rotation of local THz plasma sources and the… (More)
We experimentally demonstrate backward emission of high-harmonics of a near-infrared laser from MgO and Si crystals in the direction of specular reflection. We show that the variation of the… (More)
We generate terahertz radiation via two-color laser filamentation with average output power of 1.4 mW and peak fields of 4.4 MV/cm. We also introduce a real-time, uncooled, cost-effective… (More)
We measure the chirp in extreme ultraviolet high-harmonics from bulk MgO crystals pumped by strong near-infrared pulses using the two-color approach. By performing measurements in both reflection and… (More)
Transmission of 117.6Gb/s optical PDM-16QAM OFDM signals over 10,181km is demonstrated at 25-GHz channel spacing with 4.7 b/s/Hz spectral efficiency. All the errors have been corrected by using 25%… (More)
This paper reports long-distance transmission experiments of 100-GHz-spaced 32 /spl times/ 40 Gb/s dense wavelength-division-multiplexing (DWDM) signals, designed for submarine applications. A… (More)
Transmission of 11.5-Tb/s (115×120.5-Gb/s) is performed over 10,181km using PDM-8QAM-OFDM modulation, 60.6km hybrid fiber spans and EDFAs. Achieved spectral efficiency of 4b/s/Hz is the highest… (More)
A record spectral efficiency of 6.5 b/s/Hz over 6600 km is demonstrated using quasi-single-mode transmission over 101.6-km long hybrid few-mode and single-mode spans with high launch power.
1Tb/s quad-carrier DP-8QAM transmission over 9280 km is reported at a spectral efficiency of 4.54 b/s/Hz thanks to the proposed joint transmitter maximum a posterior (MAP) pre-distortion and receiver… (More)
400G superchannel with four parallel 100-GbE subcarriers is successfully transmitted in real-time over 3600-km of DMF link using 150-GHz bandwidth. Optical Nyquist shaping is employed to reduce… (More)
400-Gb/s dual-carrier DP-8QAM transmission over 6,787 km is reported at 121.2km span length, the longest to date with EDFA only. Spectral efficiency of 4.54 b/s/Hz is achieved thanks to Nyquist… (More)
4 × 1.15-Tb/s DP-QPSK superchannel transmission over 10,181-km of EDFA amplified hybrid large-core/ ultra low-loss fiber spans with 2-dB FEC margin
We report the first terabit/s superchannel transmission over a submarine distance >10,000 km. Four 1.15-Tb/s superchannels, each consisting of 23 optical subcarriers at 12.5-GHz spacing are modulated… (More)
The contents of betaine in differently processed root of Achyranthes bidentata were determined to be 0.930%-1.029% by reineckate precipitation and UV-visible spectrophotometry. The average recovery… (More)
The steaming process is one of traditional Chinese medicine's processing approaches for many herbs. A new HPLC peak was found in the root of Polygonum multiflorum Thunb. (PM) after steaming.… (More)
The root of Polygonum multiflorum Thunb. (Heshouwu in Chinese) is one of the most popular herbs used in traditional Chinese medicine (TCM). However, after steam processing (Zhi-heshouwu in Chinese),… (More)
The composition of the neutral essential oil from the pericarp of Trichosanthes rosthornii was analysed by means of GC and GC-MS-DS. A total of 61 compounds were identified. The major constituents… (More)
OBJECTIVE To study the relation between the content of 5-hydroxymethyl-furfural (5-HMF) and the degree of floating sugar in root of Achyranthes bidentata. METHOD An HPLC method was applied with a… (More)
Remained but entire bracts beneath the inflorescence and the persistent calyxes were selected as primary characteristics to distinguish "Yimu Cao", which derived from 8 species and 1 variety in the… (More)
Comparative study of volatile components from male and female flower buds of Populus × tomentosa by HS-SPME-GC-MS.
The differences of volatile components in male (MFB) and female flower buds (FFB) of Populus × tomentosa were analysed and compared by HS-SPME with GC-MS for the first time. A total of 34 compounds… (More)
The structure in cross section of stem and lamina of 9 species and 1 variety from genus Leonurus, whose herb used as Yimu Cao, were reported. Diagnostic characteristics were listed out in a key for… (More)
Seroprevalence of rubella antibodies in The Netherlands after 32 years of high vaccination coverage.
Semiconductor genetics is now disrupting the field of healthcare owing to the rapid parallelization and scaling of DNA sensing using ion-sensitive field-effect transistors (ISFETs) fabricated using commercial complementary metal -oxide semiconductor technology. The enabling concept of DNA reaction monitoring introduced by Toumazou has made this a reality and we are now seeing relentless scaling with Moore's law ultimately achieving the $100 genome. In this paper, we present the next evolution… CONTINUE READING
Hysteroscopy is becoming a more widely used technique. Diagnostic hysteroscopy is replacing conventional dilatation and curettage in the diagnosis of intrauterine pathologies. Transcervical endometrial resection is often the first-line surgical treatment for dysfunctional uterine bleeding and carries less associated morbidity and morality. Overall, the technique is extremely safe, but vigilance is required particularly for intravasation of irrigation media. Complications such as gas embolus and… CONTINUE READING
Acute pulmonary edema from unrecognized high irrigation pressure in hysteroscopy: a report of two cases.
This paper aims to explain the web-enabled tools for educational data mining. The proposed web-based tool developed using Asp.Net framework and php can be helpful for universities or institutions providing the students with elective courses as well improving academic activities based on feedback collected from students. In Asp.Net tool, association rule mining using Apriori algorithm is used whereas in php based Feedback Analytical Tool, feedback related to faculty and institutional… CONTINUE READING
An introduction to association rules mining: An application in counseling and help-seeking behavior of adolescents
Data Mining Applications in Higher Education. A chapter in the upcoming New Directions for Institutional Research
Normal breast tissue mainly expresses the neuropeptide Y (NPY) Y2 receptor whereas primary human breast carcinomas express the Y1 receptor (Y1R) subtype. We hypothesized that activation of estrogen signaling systems plays a role in the induction of Y1R. To investigate this possibility, we used estrogen receptor-positive (ER+) human breast carcinoma cell line, MCF-7, and examined the effect of estrogen on Y1R gene expression and its signaling pathways. Saturation binding studies revealed that… CONTINUE READING
The Neuropeptide Y Y1 Receptor: A Diagnostic Marker? Expression in MCF-7 Breast Cancer Cells Is Down-Regulated by Antiestrogens In Vitro and in Xenografts
The glucocorticoid receptor blocks P-TEFb recruitment by NFkappaB to effect promoter-specific transcriptional repression.
An isoelectric focusing method for human GDH is described which reveals seven GDH phenotypes. Family studies demonstrate that the variation is genetically determined by three alleles at an autosomal locus with gene frequencies GDH1 = 0.723, GDH2 = 0.194, GDH3 = 0.083. Linkage analysis shows that GDH may be closely linked to PGD on chromosome 1.
Identification of an Olfactory Signal Molecule that Activates the Central Regulator of Reproduction in Goats
Pheromone signals regulate conspecific behavior and physiology [1]. Releaser pheromones induce specific behavior by exerting acute effects on the neuronal response, whereas primer pheromones induce physiological changes with long-lasting effects by changing the neuroendocrine status of the recipients. In mammals, although several types of releaser pheromones have been identified [2-5], the identities of primer pheromones, as well as their mechanisms of action, remain largely unknown [6]. In… CONTINUE READING
A high level of male sexual activity is necessary for the activation of the medial preoptic area and the arcuate nucleus during the 'male effect' in anestrous goats.
Effects of Exposure to Male Goat Hair Extracts on Luteinizing Hormone Secretion and Neuronal Activation in Seasonally Anestrous Ewes
Ovary and vaginal epithelium dynamics during the estrous cycle in Dasyprocta prymnolopha Wagler, 1831: ultrasound and cytological examinations
Sexually active bucks counterbalance the seasonal negative feedback of estradiol on LH in ovariectomized goats.
Exposure of sexually inactive males to estrogenized females increased the investigative and consummatory sexual behavior.
Chronic recording of electrophysiological manifestation of the hypothalamic gonadotropin-releasing hormone pulse generator activity in the goat.
Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule.
PURPOSE A phase II trial was performed to test whether systemic low-dose interleukin-2 (IL-2) augments T-cell immune responses to a multipeptide melanoma vaccine. Forty patients with resected stage IIB-IV melanoma were randomly assigned to vaccination with four gp100- and tyrosinase-derived peptides restricted by human leukocyte antigen (HLA) -A1, HLA-A2, and HLA-A3, and a tetanus helper peptide plus IL-2 administered daily either beginning day 7 (group 1), or beginning day 28 (group 2… CONTINUE READING
A randomized pilot trial testing the safety and immunologic effects of a MAGE-A3 protein plus AS15 immunostimulant administered into muscle or into dermal/subcutaneous sites
Defining the effects of age and gender on immune response and outcomes to melanoma vaccination: a retrospective analysis of a single-institution clinical trials’ experience
A melanoma helper peptide vaccine increases Th1 cytokine production by leukocytes in peripheral blood and immunized lymph nodes
1. The innervation densities of mechanoreceptive fibres supplying the ridged glabrous skin of the middle and terminal phalanges of the monkey's (Macaca nemestrina) index finger were estimated using a combination of histological and neurophysiological procedures. 2. This estimate was based on (a) a count of the total number of A beta myelinated fibres in the palmar digital nerve at the level of the proximal phalanx, (b) the demonstration that the majority of A beta fibres in the monkey's palmar… CONTINUE READING
SA1 and RA receptive fields, response variability, and population responses mapped with a probe array.
Monkey cutaneous SAI and RA responses to raised and depressed scanned patterns: effects of width, height, orientation, and a raised surround.
Tactile resolution: peripheral neural mechanisms underlying the human capacity to determine positions of objects contacting the fingerpad.
Apomorphine (0.01-0.5 mg/kg) disrupted fighting between two male ferrets. The number of bites and neck nuzzling were decreased dose-dependently. At 0.05 and 0.1 mg/kg scent-marking and collateral behaviour were increased, at 0.5 mg/kg stereotyped sniffing was induced. L-dopa (120 mg/kg + 30 mg/kg benserazide) exerted similar effects to apomorphine 0.05 mg/kg. Thus, the dopamine (DA) agonists increased short chain responses but disrupted long ones. Haloperidol (0.2 mg/kg) facilitated inter-male… CONTINUE READING
Effects of systemically and intrastriatally injected haloperidol and apomorphine on grooming, feeding and locomotion in the rat.
UNLABELLED The surgical treatment of benign liver tumours (focal nodular hyperplasia (FNH) and hepatic adenoma) remains controversial. From 1984 to 1990, all 51 women aged below 50 years who presented with presumed benign liver tumours and without chronic liver disease underwent tumour resection. Preoperative assessment included liver tests, ultrasonography and dynamic computed tomography in all patients, plus angiography (n = 20), magnetic resonance imaging (n = 22) and technetium-sulphur… CONTINUE READING
What is Changing in Indications and Treatment of Focal Nodular Hyperplasia of the Liver. Is There Any Place for Surgery?
The ISCL/EORTC recommends revisions to the Mycosis Fungoides Cooperative Group classification and staging system for cutaneous T-cell lymphoma (CTCL). These revisions are made to incorporate advances related to tumor cell biology and diagnostic techniques as pertains to mycosis fungoides (MF) and Sézary syndrome (SS) since the 1979 publication of the original guidelines, to clarify certain variables that currently impede effective interinstitution and interinvestigator communication and/or the… CONTINUE READING
CD4+CD26- lymphocytes are useful to assess blood involvement and define B ratings in cutaneous T cell lymphoma.
Tissue and serum lipidome shows altered lipid composition with diagnostic potential in mycosis fungoides
Efficacy and Side Effects of Narrowband-UVB in Early Stage Cutaneous T-Cell Lymphoma in Jordanian Patients
Sézary cell counts in erythrodermic cutaneous T-cell lymphoma: implications for prognosis and staging.
Analysis of T-cell receptor gene rearrangement for predicting clinical outcome in patients with cutaneous T-cell lymphoma: a comparison of Southern blot and polymerase chain reaction methods.
Histopathologic features of early (patch) lesions of mycosis fungoides: a morphologic study on 745 biopsy specimens from 427 patients.
Increased risk for second lymphomas in patients with mycosis fungoides and Sézary syndrome [abstract
Is bone marrow biopsy necessary in patients with mycosis fungoides and Sézary syndrome? A histological and molecular study at diagnosis and during follow-up.