Christie Brinkley has been embroiled in a bitter battle with her ex-husband Peter Cook, from whom she divorced after he admitted to an affair with a teenager, and told Matt Lauer on "Today" that she just wants "peace."
Christie Brinkley let her guard down in a chat with Matt Lauer on "Today" and revealed how emotionally grueling the fallout from her last divorce has been.
Embroiled in the bitter aftermath with ex-husband Peter Cook, who admitted to an affair with an 18-year-old during their marriage, the supermodel-turned-actress choked up Tuesday as she opened up about a recent exchange of court papers.
"I just want peace. And every time I have any joy or any kind of success in anything, he has to try to destroy it," she said.
Brinkley filed papers in November saying that Cook kept sending her angry emails in violation of their 2008 divorce agreement and had failed to pay what he owed in child support.
Cook responded in February with his own papers calling the supermodel a "narcissistic egomaniac." He said his ex-wife owed him money and was only filing papers to drum up publicity for her career.
"There's not one quote from me, anywhere. This is the first time I've ever been on a show" to discuss it, she said.
Earlier this month, Cook, in an ABC News interview with Barbara Walters, accused his ex-wife of throwing their family under the bus.
On Tuesday, Brinkley and Lauer never got around to discussing Brinkley's return next week to Broadway to star in the musical "Chicago."
Brinkley is set to play the murderess turned media sensation Roxie Hart in a three-week limited engagement on Broadway and then in the show's national tour, Playbill reported.
After five months, The Jay Leno Show faltered in prime-time and the network decided to move Leno back to Tonight. Conan O'Brien accepted a $33 million (plus $12 million for his staff) deal to leave NBC and The Tonight Show after a heated debate over the future of the show.
However, in a new interview with "60 Minutes," it appears CoCo isn't so sweet on the way Jay handled the whole "Tonight Show" situation.
"He went and took that show back and I think in a similar situation, if roles had been reversed, I know — I know me, I wouldn't have done that," Conan said.
In the interview with Steve Kroft, which airs on Sunday, Conan – whose new TBS late night series will debut in November – said had the roles been reversed, he would've handled things differently.
"If I had surrendered 'The Tonight Show' and handed it over to somebody publicly and wished them well — and then…six months later. But that's me, you know. Everyone's got their own, you know, way of doing things," he added.
As far as his decision to leave NBC, Conan said he felt it was best for both sides to go their separate ways.
"I [thought] this relationship is going be toxic and maybe we just need to go our separate ways," he recounted. "That's really how it felt to me… and I started to feel that I'm not sure these people even really want me here….I can't do it [anymore]."
Plans for the Young Money rapper to perform an outdoor concert for ABC's "Good Morning America" summer concert series on July 16 have been scrapped, according to MTV News.
According to MTV News, a spokesperson for ABC reported that the network was "interested in having Drake perform, but he was never officially booked." The Canadian rapper's rep mentioned that there was a "booking in place" but failed to give any detailed information regarding the cancellation.
According to the New York Daily News, ABC decided to go a different route after "NYPD told the city Parks Department that parks' security plan wasn't up to snuff."
It was only a month ago that Drake's free concert at New York's South Street Seaport was cancelled when over 10,000 riotous fans unexpectedly arrived at the concert grounds.
It's rumored that the NYPD decided to pull the plug on Drizzy's "GMA" stage appearance after the NYC Department of Parks & Recreation predicted they wouldn't be able to provide adequate security to the rapper and concertgoers. According to MTV News, The parks' department rep has neither confirmed nor denied whether security issues factored in to the cancellation of Drake's performance.
Kayne West jumps onstage after Taylor Swift won the award for Best Female Video and took the mic from her.
Taylor Swift said Kanye West called her today to apologize for interrupting her speech during the MTV Video Music Awards over the weekend.
"Kanye did call me, and he was very sincere in his apology and I accepted that apology," she told ABC News Radio.
Earlier today, Swift appeared on ABC's "The View" and told the ladies this morning that the hip hop artist had not reached out to her to personally apologize despite his public appeals for forgiveness.
"He has not personally reached out to me or anything," Swift said on "The View" today. "But if he wanted to say hi... "
Reps at "The View" told gossip website TMZ.com that Kanye called to apologize following the show and that Swift accepted.
The 17-year-old starlet said she was stunned when hip hop artist Kanye bounded onto the stage during the award ceremony at Radio City Music Hall Sunday night, ripped the microphone out of her hand and began to argue she didn't deserve to win the award.
"My overall thought process went something like, 'Wow, I can't believe I won. This is awesome,'" she told the ladies on "The View."
"'Don't trip and fall. I'm going to get to thank the fans, this is so cool ... Oh, Kanye West is here! Cool haircut! What are you doing there? And then, ouch. And then, I guess I'm not going to thank the fans."
Kanye expressed regret for pulling the stunt on his blog and later gave a tearful apology on "The Jay Leno Show."
"I'm not going to say that I wasn't rattled by it," Swift said today, "but I had to perform live five minutes later so I had to get myself back to the place where I could perform."
Stars flocked to Swift's defense and the songstress said she found the overwhelming support to be heartwarming.
"I just never imagined that there were that many people our there looking out for me, so it was really wonderful to see that people were out there defending me so I didn't have to."
A 20-year-old man was found shot to death inside a car in Forest Heights, Maryland, on Thanksgiving Day, Prince George's County police said.
Officers were called to the 100 block of Cree Drive about 6 a.m. for a report of a suspicious car parked in the area. When they arrived, they found Aaron Taylor dead inside the vehicle.
Anyone with information that can help police is asked to call 301-772-4925. A reward of up to $25,000 is being offered for information that leads to an arrest and indictment in the case.
One of the gravest concerns expressed to me by my constituents has to do with their safety. Therefore, one of my gravest concerns as a legislator is to see to it that we take every reasonable precaution for ensuring the safety and wellbeing of every citizen and visitor to our state.
We must follow that up by supporting and showing our appreciation for the tens of thousands of law enforcement officers, firefighters, emergency responders, national guardsmen, and military personnel who unselfishly give of themselves and risk their lives to protect us.
Thirty-six CA patients were randomly divided into two groups, 19 in the test group treated with lentinan plus CO2 laser irradiation and 17 in the control group treated with laser irradiation alone. Their T-lymphocyte subsets of peripheral blood and level of serum interleukin-2 (IL-2) and soluable interleukin-2 receptor (SIL-2R) were determined before and after treatment, and the recurrence rates of the two groups were compared.
After treatment, in the test group, the CD4/CD8 ratio, serum IL-2 raised and serum SIL-2R lowered significantly (P < 0.05, 0.05, 0.05 respectively) as compared with before treatment, while those parameters were not changed significantly in the control group. The recurrence rate of the test group was lower than that of the control group, P < 0.05.
Lentinan could modulate the cellular immunofunction of CA patients and reduce the recurrence rate of CA.
The ABC transporters are ubiquitous membrane proteins that couple adenosine triphosphate (ATP) hydrolysis to the translocation of diverse substrates across cell membranes. Clinically relevant examples are associated with cystic fibrosis and with multidrug resistance of pathogenic bacteria and cancer cells. Here, we report the crystal structure at 3.2 angstrom resolution of the Escherichia coli BtuCD protein, an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and appears to represent a conserved motif among the ABC transporters.
The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions. - PubMed - NCBI
A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the effect of NSO, nigellone and thymoquinone were studied on insulin secretion of isolated rat pancreatic islets in the presence of 3, 5.6 or 11.1 mM glucose. NSO significantly lowered blood glucose concentrations in diabetic rats after 2, 4 and 6 weeks. The blood lowering effect of NSO was, however, not paralleled by a stimulation of insulin release in the presence of NSO, nigellone or thymoquinone. The data indicate that the hypoglycemic effect of NSO may be mediated by extrapancreatic actions rather than by stimulated insulin release.
Outcomes of a Coaching-Based WHO Safe Childbirth Checklist Program in India. Semrau KEA et al. N Engl J Med. (2017)
Determining the effect of different environmental conditions on Ebola virus viability in clinically relevant specimens.
SMARCA4-Deficient Carcinoma of Unknown Primary Presenting with Fatal Paraneoplastic Hypercalcemia in a Heart Transplant Recipient: First Report in a Male Patient.
Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial.
Variability of interferon-λ induction and antiviral activity in Nipah virus infected differentiated human bronchial epithelial cells of two human donors.
Synthesis and Biological Evaluation of Benzocyclooctene-based and Indene-based Anticancer Agents that Function as Inhibitors of Tubulin Polymerization.
Synthesis and biological evaluation of a water-soluble phosphate prodrug salt and structural analogues of KGP94, a lead inhibitor of cathepsin L.
Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015.
Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents.
Pathogen-reduced Ebola virus convalescent plasma: first steps towards standardization of manufacturing and quality control including assessment of Ebola-specific neutralizing antibodies.
Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L.
The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts.
Plant diversity drives soil microbial biomass carbon in grasslands irrespective of global environmental change factors.
Field Evaluation of Capillary Blood Samples as a Collection Specimen for the Rapid Diagnosis of Ebola Virus Infection During an Outbreak Emergency.
Effects of plant diversity, functional group composition, and fertilization on soil microbial properties in experimental grassland.
Flooding disturbances increase resource availability and productivity but reduce stability in diverse plant communities.
No evidence of complementary water use along a plant species richness gradient in temperate experimental grasslands.
Evidence for a decrease in transmission of Ebola virus--Lofa County, Liberia, June 8-November 1, 2014.
Pathological findings in cardiac apex removed during implantation of left ventricular assist devices (LVAD) are non-specific: 13-year-experience at a German Heart Center.
Interaction with Tsg101 is necessary for the efficient transport and release of nucleocapsids in marburg virus-infected cells.
Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents.
Inflammatory thoracic aortic aneurysm (lymphoplasmacytic thoracic aortitis): a 13-year-experience at a German Heart Center with emphasis on possible role of IgG4.
Study after study tells us there is an epidemic of burnout in our profession. As an emergency physician I have experienced it personally, and as a coach who works with physicians I see it every day in my clients.
The reasons for burnout are increasingly well understood. Rapid changes in healthcare have brought a loss of physician autonomy, increased administrative minutiae, and unreasonable performance expectations. These compound the more traditional challenges of constantly dealing with death and suffering, high-stakes decision making, and long, irregular work hours.
As a physician, these hurdles can seem insurmountable. However, as a coach I know that physicians with burnout can recover and even thrive. When I begin to coach a physician, I often start with thought exercises to pinpoint the areas of their life that need immediate attention and have real potential for improvement. The exercises below are two of my favorites:
When someone is burned out, it is natural for them to ruminate over external causes, vent frustrations, and assign blame. It is far more difficult to shift into a positive mindset and visualize an ideal work day, from wake to sleep, in minute detail. Making a deliberate effort to do this forces them to see the large and small areas of joy and difficulty both at work and at home. I ask clients to log their actual workdays for a week. After completing this exercise, physicians are often shocked at just how much of their day is unintentional. There are almost always several clear areas ripe for relatively easy improvements.This question, “What is your ideal day?” is also powerful simply because most physicians I work with have never thought about this before. Once individuals identify the things that are important to them, it is much easier to address barriers and begin taking specific steps to achieve their ideals.
If you could wake up tomorrow and find that miraculously one part of your job could be permanently changed, what would it be?
This question forces physicians to zero in on where they are struggling the most. The Pareto Principle tells us that 80% of our job dissatisfaction is caused by only 20% of our work activities. Therefore, making even small improvements in the most frustrating activities can drive enormous increases in our work satisfaction. This exercise is about identifying concrete stressors so that the individual has the opportunity to take specific actions to improve his or her situation.
The real power of these coaching questions is that they begin the process of reclaiming an internal locus of control. They help physicians shift from a state of passive frustration and victimization to a mindset of engagement and change. Physicians who recover from burnout do so not because they discover a single silver bullet for the problem, but because they ask themselves what they truly want in each area of their lives, and then act to bring about change to that effect. Being burned out is a lonely and even desperate place to be. I find it reassures physicians to understand that even a small positive first step can lead to meaningful and lasting change for the better.
Dr. Ryan Bayley is a board certified emergency physician and a professional development coach. Through his coaching practice he works with physicians on a wide range of career and leadership issues, with a particular interest in burnout and work-life balance. He can be reached at rb@ryanbayleymd.com.
“burnout” seems to mean not wishing to go to work and dreading being at work. This would describe at least 90% of America’s work force. There are reasons for this angst, but first, I think one would be well advised to use better terms that “burnout.”
The first reason for major depression in the medical field is the structure and content of medical education, leading future providers with a false expectation.
The second reason is that the profession is structured around memory and source orientation, both of which obfuscate the path to reasonable solutions to the patient’s problems.
The third reason is the unending messages that providers are special and preoccupation with money. The entire EMR is built around satisfying the craving of the system for money.
Interesting that providers coming back from mission trips feel they have regained some of their soul, at least temporarily…
I have been part of a physician support group that meets twice annually for 3 days. In addition to group activities, each physicians gets an hour to share aspects of their life, work, family, personal growth and deal with physical, mental, emotional and spiritual concerns.
Burn out does NOT equate with major depression.And providers as you call them ARE special, we have much more responsibility than most but not all other occupations. Not too many physicians would disagree that EMR is a major detriment to health care delivery and to physician satisfaction.
In an action to be more transparent, the 15 Catholic dioceses in Texas will release the names of clergy who were credibly accused of sexually abusing a minor, according to an Oct. 10 statement issued by the Texas Catholic Conference of Bishops.
As police investigated a series of package explosions in central Texas that killed two people and injured four others, two of the state's bishops said their thoughts and prayers were with the victims and families and friends of those victimized by the explosions.
Catholics by the thousands joined their bishops who lead the state's 15 dioceses at the Texas Capitol as one voice advocating for a number of issues as legislators met April 4.