Manchester United F.C. mùa giải 2005–06
Ngoại hạng Anh

| Ngày | Đối thủ | Sân nhà/khách | Tỉ số | Cầu thủ ghi bàn | Số lượng khán giả | Thứ hạng |
| --- | --- | --- | --- | --- | --- | --- |
| 13/8/2005 | Everton | A | 2–0 | Van Nistelrooy 43', Rooney 46' | 38,610 | 4 |
| 20/8/2005 | Aston Villa | H | 1–0 | Van Nistelrooy 66' | 67,934 | 4 |
| 28/8/2005 | Newcastle United | A | 2–0 | Rooney 66', Van Nistelrooy 90' | 52,327 | 4 |
| 10/9/2005 | Manchester City | H | 1–1 | Van Nistelrooy 45' | 67,839 | 4 |
| 18/9/2005 | Liverpool | A | 0–0 |  | 44,917 | 3 |
| 24/9/2005 | Blackburn Rovers | H | 1–2 | Van Nistelrooy 67' | 67,765 | 6 |
| 1/10/2005 | Fulham | A | 3–2 | Van Nistelrooy (2) 16' (pen.), 44', Rooney 17' | 21,862 | 4 |
| 15/10/2005 | Sunderland | A | 3–1 | Rooney 40', Van Nistelrooy 76', Rossi 87' | 39,085 | 3 |
| 22/10/2005 | Tottenham Hotspur | H | 1–1 | Silvestre 7' | 67,856 | 5 |
| 29/10/2005 | Middlesbrough | A | 1–4 | Ronaldo 90' | 30,579 | 7 |
| 6/11/2005 | Chelsea | H | 1–0 | Fletcher 31' | 67,864 | 4 |
| 19/11/2005 | Charlton Athletic | A | 3–1 | Smith 37', Van Nistelrooy (2) 70', 85' | 26,730 | 3 |
| 27/11/2005 | West Ham United | A | 2–1 | Rooney 47', O'Shea 56' | 34,755 | 2 |
| 3/12/2005 | Portsmouth | H | 3–0 | Scholes 20', Rooney 80', Van Nistelrooy 84' | 67,684 | 2 |
| 11/12/2005 | Everton | H | 1–1 | Giggs 15' | 67,831 | 3 |
| 14/12/2005 | Wigan Athletic | H | 4–0 | Ferdinand 30', Rooney (2) 35', 55', Van Nistelrooy 70' (pen.) | 67,793 | 2 |
| 17/12/2005 | Aston Villa | A | 2–0 | Van Nistelrooy 10', Rooney 51' | 37,128 | 2 |
| 26/12/2005 | West Bromwich Albion | H | 3–0 | Scholes 35', Ferdinand 45', Van Nistelrooy 63' | 67,972 | 2 |
| 28/12/2005 | Birmingham City | A | 2–2 | Van Nistelrooy 4', Rooney 53' | 28,459 | 2 |
| 31/12/2005 | Bolton Wanderers | H | 4–1 | Ngotty 8' (o.g.), Saha 44', Ronaldo (2) 68', 90' | 67,858 | 2 |
| 3/1/2006 | Arsenal | A | 0–0 |  | 38,313 | 2 |
| 14/1/2006 | Manchester City | A | 1–3 | Van Nistelrooy 76' | 47,192 | 2 |
| 22/1/2006 | Liverpool | H | 1–0 | Ferdinand 90' | 67,874 | 2 |
| 1/2/2006 | Blackburn Rovers | A | 3–4 | Saha 37', Van Nistelrooy (2) 63', 65' | 25,484 | 2 |
| 4/2/2006 | Fulham | H | 4–2 | Bocanegra 6' (o.g.), Ronaldo (2) 14', 86', Saha 23' | 67,844 | 2 |
| 11/2/2006 | Portsmouth | A | 3–1 | Van Nistelrooy 18', Ronaldo (2) 38', 45' | 20,206 | 2 |
| 6/3/2006 | Wigan Athletic | A | 2–1 | Ronaldo 74', Chimbonda 90' (o.g.) | 23,524 | 2 |
| 12/3/2006 | Newcastle United | H | 2–0 | Rooney (2) 8', 12' | 67,858 | 2 |
| 18/3/2006 | West Bromwich Albion | A | 2–1 | Saha (2) 16', 64' | 27,623 | 2 |
| 26/3/2006 | Birmingham City | H | 3–0 | Taylor 3' (o.g.), Giggs 15', Rooney 83' | 69,070 | 2 |
| 29/3/2006 | West Ham United | H | 1–0 | Van Nistelrooy 45' | 69,522 | 2 |
| 1/4/2006 | Bolton Wanderers | A | 2–1 | Saha 33', Van Nistelrooy 79' | 27,718 | 2 |
| 9/4/2006 | Arsenal | H | 2–0 | Rooney 54', Park 78' | 70,908 | 2 |
| 14/4/2006 | Sunderland | H | 0–0 |  | 72,519 | 2 |
| 17/4/2006 | Tottenham Hotspur | A | 2–1 | Rooney (2) 8', 36' | 36,141 | 2 |
| 29/4/2006 | Chelsea | A | 0–3 |  | 42,219 | 2 |
| 1/5/2006 | Middlesbrough | H | 0–0 |  | 69,531 | 2 |
| 7/5/2006 | Charlton Athletic | H | 4–0 | Saha 19', Ronaldo 23', Euell 34' (o.g.), Richardson 58' | 73,006 | 2 |