Başrolde Erkek Oyuncu Tarafından Üstün Performans Ekran Oyuncuları Derneği Ödülü
Kazananlar ve adaylar > 2000'ler

| Yıl | Aday | Film | Rol(ler) |
| --- | --- | --- | --- |
| 2000 (7.)  | Benicio del Toro †† | Traffic | Javier Rodriguez |
| 2000 (7.)  | Jamie Bell | Billy Elliot | Billy Elliot |
| 2000 (7.)  | Russell Crowe † | Gladiator | Maximus Decimus Meridius |
| 2000 (7.)  | Tom Hanks ‡ | Cast Away | Chuck Noland |
| 2000 (7.)  | Geoffrey Rush ‡ | Quills | Marquis de Sade |
| 2001 (8.)  | Russell Crowe ‡ | A Beautiful Mind | John Forbes Nash Jr. |
| 2001 (8.)  | Kevin Kline | Life as a House | George Monroe |
| 2001 (8.)  | Sean Penn ‡ | I Am Sam | Sam Dawson |
| 2001 (8.)  | Denzel Washington † | Training Day | Alonzo Harris |
| 2001 (8.)  | Tom Wilkinson ‡ | In the Bedroom | Matt Fowler |
| 2002 (9.)  | Daniel Day-Lewis ‡ | Gangs of New York | William "Bill the Butcher" Cutting |
| 2002 (9.)  | Adrien Brody † | The Pianist | Władysław "Wladek" Szpilman |
| 2002 (9.)  | Nicolas Cage ‡ | Adaptation. | Charlie Kaufman / Donald Kaufman |
| 2002 (9.)  | Richard Gere | Chicago | Billy Flynn |
| 2002 (9.)  | Jack Nicholson ‡ | About Schmidt | Warren Schmidt |
| 2003 (10.)  | Johnny Depp ‡ | Pirates of the Caribbean: The Curse of the Black Pearl | Captain Jack Sparrow |
| 2003 (10.)  | Peter Dinklage | The Station Agent | Finbar McBride |
| 2003 (10.)  | Ben Kingsley ‡ | House of Sand and Fog | Colonel Massoud Amir Behrani |
| 2003 (10.)  | Bill Murray ‡ | Lost in Translation | Bob Harris |
| 2003 (10.)  | Sean Penn † | Mystic River | Jimmy Markum |
| 2004 (11.)  | Jamie Foxx † | Ray | Ray Charles |
| 2004 (11.)  | Don Cheadle ‡ | Hotel Rwanda | Paul Rusesabagina |
| 2004 (11.)  | Johnny Depp ‡ | Finding Neverland | J. M. Barrie |
| 2004 (11.)  | Leonardo DiCaprio ‡ | The Aviator | Howard Hughes |
| 2004 (11.)  | Paul Giamatti | Sideways | Miles Raymond |
| 2005 (12.)  | Philip Seymour Hoffman † | Capote | Truman Capote |
| 2005 (12.)  | Russell Crowe | Cinderella Man | Jim Braddock |
| 2005 (12.)  | Heath Ledger ‡ | Brokeback Mountain | Ennis Del Mar |
| 2005 (12.)  | Joaquin Phoenix ‡ | Walk the Line | Johnny Cash |
| 2005 (12.)  | David Strathairn ‡ | Good Night, and Good Luck. | Edward R. Murrow |
| 2006 (13.)  | Forest Whitaker † | The Last King of Scotland | Idi Amin |
| 2006 (13.)  | Leonardo DiCaprio ‡ | Blood Diamond | Danny Archer |
| 2006 (13.)  | Ryan Gosling ‡ | Half Nelson | Dan Dunne |
| 2006 (13.)  | Peter O'Toole ‡ | Venus | Maurice Russell |
| 2006 (13.)  | Will Smith ‡ | The Pursuit of Happyness | Chris Gardner |
| 2007 (14.)  | Daniel Day-Lewis † | There Will Be Blood | Daniel Plainview |
| 2007 (14.)  | George Clooney ‡ | Michael Clayton | Michael Clayton |
| 2007 (14.)  | Ryan Gosling | Lars and the Real Girl | Lars Lindstrom |
| 2007 (14.)  | Emile Hirsch | Into the Wild | Christopher McCandless |
| 2007 (14.)  | Viggo Mortensen ‡ | Eastern Promises | Nikolai Luzhin |
| 2008 (15.)  | Sean Penn † | Milk | Harvey Milk |
| 2008 (15.)  | Richard Jenkins ‡ | The Visitor | Walter Vale |
| 2008 (15.)  | Frank Langella ‡ | Frost/Nixon | Richard Nixon |
| 2008 (15.)  | Brad Pitt ‡ | The Curious Case of Benjamin Button | Benjamin Button |
| 2008 (15.)  | Mickey Rourke ‡ | The Wrestler | Randy "The Ram" Robinson |
| 2009 (16.)  | Jeff Bridges † | Crazy Heart | Otis "Bad" Blake |
| 2009 (16.)  | George Clooney ‡ | Up in the Air | Ryan Bingham |
| 2009 (16.)  | Colin Firth ‡ | A Single Man | George Falconer |
| 2009 (16.)  | Morgan Freeman ‡ | Invictus | Nelson Mandela |
| 2009 (16.)  | Jeremy Renner ‡ | The Hurt Locker | Staff Sgt. First Class William James |