En İyi Kadın Oyuncu Altın Küre Ödülü - Müzikal veya Komedi Filmi
Kazananlar ve adaylar > 2000'ler

| Yıl | Oyuncu | Rol | Film |
| --- | --- | --- | --- |
| 2000 | Renée Zellweger §  | Betty Sizemore  | Nurse Betty |
| 2000 | Juliette Binoche ‡ | Vianne Rocher | Chocolat |
| 2000 | Brenda Blethyn | Grace Trevethyn | Saving Grace |
| 2000 | Sandra Bullock | Gracie Hart | Miss Congeniality |
| 2000 | Tracey Ullman | Frenchy Jackson | Small Time Crooks |
| 2001 | Nicole Kidman ‡  | Satine | Moulin Rouge! |
| 2001 | Thora Birch | Enid Wilson | Ghost World |
| 2001 | Cate Blanchett | Kate Wheeler | Bandits |
| 2001 | Reese Witherspoon | Elle Woods | Legally Blonde |
| 2001 | Renée Zellweger ‡ | Bridget Jones | Bridget Jones's Diary |
| 2002 | Renée Zellweger ‡  | Roxie Hart | Chicago |
| 2002 | Maggie Gyllenhaal | Lee Holloway | Secretary |
| 2002 | Goldie Hawn | Suzette Crooks | The Banger Sisters |
| 2002 | Nia Vardalos | Toula Portokalos | My Big Fat Greek Wedding |
| 2002 | Catherine Zeta-Jones † | Velma Kelly | Chicago |
| 2003 | Diane Keaton ‡  | Erica Jane Barry | Something's Gotta Give |
| 2003 | Jamie Lee Curtis | Anna Coleman/Tess Coleman | Freaky Friday |
| 2003 | Scarlett Johansson | Charlotte Riley | Lost in Translation |
| 2003 | Diane Lane | Frances Mayes | Under the Tuscan Sun |
| 2003 | Helen Mirren | Chris Harper | Calendar Girls |
| 2004 | Annette Bening ‡  | Julia Lambert | Being Julia |
| 2004 | Ashley Judd | Linda Porter | De-Lovely |
| 2004 | Emmy Rossum | Christine Daaé | The Phantom of the Opera |
| 2004 | Kate Winslet ‡ | Clementine Kruczynski | Eternal Sunshine of the Spotless Mind |
| 2004 | Renée Zellweger | Bridget Jones | Bridget Jones: The Edge of Reason |
| 2005 | Reese Witherspoon †  | June Carter | Walk the Line |
| 2005 | Judi Dench ‡ | Laura Henderson | Mrs Henderson Presents |
| 2005 | Keira Knightley ‡ | Elizabeth Bennet | Pride & Prejudice |
| 2005 | Laura Linney | Joan Berkman | The Squid and the Whale |
| 2005 | Sarah Jessica Parker | Meredith Morton | The Family Stone |
| 2006 | Meryl Streep ‡  | Miranda Priestly | The Devil Wears Prada |
| 2006 | Annette Bening | Deirdre Burroughs | Running with Scissors |
| 2006 | Toni Collette | Sheryl Hoover | Little Miss Sunshine |
| 2006 | Beyoncé Knowles | Deena Jones | Dreamgirls |
| 2006 | Renée Zellweger | Beatrix Potter | Miss Potter |
| 2007 | Marion Cotillard †  | Édith Piaf  | La Vie en Rose |
| 2007 | Amy Adams | Giselle | Enchanted |
| 2007 | Nikki Blonsky | Tracy Turnblad | Hairspray |
| 2007 | Helena Bonham Carter | Mrs. Lovett | Sweeney Todd: The Demon Barber of Fleet Street |
| 2007 | Ellen Page ‡ | Juno MacGuff | Juno |
| 2008 | Sally Hawkins §  | Pauline "Poppy" Cross | Happy-Go-Lucky |
| 2008 | Rebecca Hall | Vicky Marielle | Vicky Cristina Barcelona |
| 2008 | Frances McDormand | Linda Litzke | Burn After Reading |
| 2008 | Meryl Streep | Donna Sheridan | Mamma Mia! |
| 2008 | Emma Thompson | Kate Walker | Last Chance Harvey |
| 2009 | Meryl Streep ‡  | Julia Child | Julie & Julia |
| 2009 | Sandra Bullock | Margaret Tate | The Proposal |
| 2009 | Marion Cotillard | Luisa Contini | Nine |
| 2009 | Julia Roberts | Claire Stenwick | Duplicity |
| 2009 | Meryl Streep | Jane Adler | It's Complicated |