En İyi Erkek Oyuncu MTV Film Ödülü
Kazananlar ve adaylar > 2000s

| Year | Category | Actor | Film | Character |
| --- | --- | --- | --- | --- |
| 2000 9. | Erkek Performansı | Keanu Reeves | The Matrix | Neo |
| 2000 9. | Erkek Performansı | Jim Carrey | Man on the Moon | Andy Kaufman |
| 2000 9. | Erkek Performansı | Ryan Phillippe | Cruel Intentions | Sebastian Valmont |
| 2000 9. | Erkek Performansı | Adam Sandler | Big Daddy | Sonny Koufax |
| 2000 9. | Erkek Performansı | Bruce Willis | The Sixth Sense | Dr. Malcolm Crowe |
| 2000 9. | Kadın Performansı | Sarah Michelle Gellar | Cruel Intentions | Kathryn Merteuil |
| 2000 9. | Kadın Performansı | Drew Barrymore | Never Been Kissed | Josie Geller |
| 2000 9. | Kadın Performansı | Neve Campbell | Scream 3 | Sidney Prescott |
| 2000 9. | Kadın Performansı | Ashley Judd | Double Jeopardy | Libby Parsons |
| 2000 9. | Kadın Performansı | Julia Roberts | Runaway Bride | Maggie Carpenter |
| 2001 10. | Erkek Performansı | Tom Cruise | Mission: Impossible 2 | Ethan Hunt |
| 2001 10. | Erkek Performansı | Russell Crowe † | Gladiator | Maximus |
| 2001 10. | Erkek Performansı | Omar Epps | Love & Basketball | Quincy McCall |
| 2001 10. | Erkek Performansı | Mel Gibson | The Patriot | Benjamin Martin |
| 2001 10. | Erkek Performansı | Tom Hanks ‡ | Cast Away | Chuck Noland |
| 2001 10. | Kadın Performansı | Julia Roberts † | Erin Brockovich | Erin Brockovich |
| 2001 10. | Kadın Performansı | Aaliyah | Romeo Must Die | Trish O'Day |
| 2001 10. | Kadın Performansı | Kate Hudson ‡ | Almost Famous | Penny Lane |
| 2001 10. | Kadın Performansı | Jennifer Lopez | The Cell | Dr. Catherine Deane |
| 2001 10. | Kadın Performansı | Julia Stiles | Save the Last Dance | Sara Johnson |
| 2002 11. | Erkek Performansı | Will Smith ‡ | Ali | Muhammad Ali |
| 2002 11. | Erkek Performansı | Russell Crowe ‡ | A Beautiful Mind | John Nash |
| 2002 11. | Erkek Performansı | Josh Hartnett | Pearl Harbor | Lieutenant Danny Walker |
| 2002 11. | Erkek Performansı | Vin Diesel | The Fast and the Furious | Dominic Toretto |
| 2002 11. | Erkek Performansı | Elijah Wood | The Lord of the Rings: The Fellowship of the Ring | Frodo Baggins |
| 2002 11. | Kadın Performansı | Nicole Kidman ‡ | Moulin Rouge! | Satine |
| 2002 11. | Kadın Performansı | Kate Beckinsale | Pearl Harbor | Nurse Evelyn Johnson |
| 2002 11. | Kadın Performansı | Halle Berry † | Monster's Ball | Leticia Musgrove |
| 2002 11. | Kadın Performansı | Angelina Jolie | Lara Croft: Tomb Raider | Lara Croft |
| 2002 11. | Kadın Performansı | Reese Witherspoon | Legally Blonde | Elle Woods |
| 2003 12. | Erkek Performansı | Eminem | 8 Mile | Jimmy "B-Rabbit" Smith |
| 2003 12. | Erkek Performansı | Vin Diesel | xXx | Xander Cage |
| 2003 12. | Erkek Performansı | Leonardo DiCaprio | Catch Me If You Can | Frank Abagnale |
| 2003 12. | Erkek Performansı | Tobey Maguire | Spider-Man | Peter Parker / Spider-Man |
| 2003 12. | Erkek Performansı | Viggo Mortensen | Yüzüklerin Efendisi: İki Kule | Aragorn |
| 2003 12. | Kadın Performansı | Kirsten Dunst | Spider-Man | Mary Jane Watson |
| 2003 12. | Kadın Performansı | Halle Berry | Die Another Day | Jinx |
| 2003 12. | Kadın Performansı | Kate Hudson | How to Lose a Guy in 10 Days | Andie Anderson |
| 2003 12. | Kadın Performansı | Queen Latifah ‡ | Chicago | Matron Morton |
| 2003 12. | Kadın Performansı | Reese Witherspoon | Sweet Home Alabama | Melanie Carmichael |
| 2004 13. | Erkek Performansı | Johnny Depp ‡ | Pirates of the Caribbean: The Curse of the Black Pearl | Jack Sparrow |
| 2004 13. | Erkek Performansı | Jim Caviezel | The Passion of the Christ | Jesus Christ |
| 2004 13. | Erkek Performansı | Tom Cruise | The Last Samurai | Cpt. Nathan Algren |
| 2004 13. | Erkek Performansı | Bill Murray ‡ | Lost in Translation | Bob Harris |
| 2004 13. | Erkek Performansı | Adam Sandler | 50 First Dates | Henry Roth |
| 2004 13. | Kadın Performansı | Uma Thurman | Kill Bill: Volume 1 | The Bride |
| 2004 13. | Kadın Performansı | Drew Barrymore | 50 First Dates | Lucy Whitmore |
| 2004 13. | Kadın Performansı | Halle Berry | Gothika | Miranda Grey |
| 2004 13. | Kadın Performansı | Queen Latifah | Bringing Down the House | Charlene Morton |
| 2004 13. | Kadın Performansı | Charlize Theron † | Monster | Aileen Wuornos |
| 2005 14. | Erkek Performansı | Leonardo DiCaprio ‡ | The Aviator | Howard Hughes |
| 2005 14. | Erkek Performansı | Matt Damon | The Bourne Supremacy | Jason Bourne |
| 2005 14. | Erkek Performansı | Jamie Foxx † | Ray | Ray Charles |
| 2005 14. | Erkek Performansı | Brad Pitt | Troy | Achilles |
| 2005 14. | Erkek Performansı | Will Smith | Hitch | Hitch |
| 2005 14. | Kadın Performansı | Lindsay Lohan | Mean Girls | Cady Heron |
| 2005 14. | Kadın Performansı | Rachel McAdams | The Notebook | Allie Hamilton |
| 2005 14. | Kadın Performansı | Natalie Portman | Garden State | Sam |
| 2005 14. | Kadın Performansı | Hilary Swank † | Million Dollar Baby | Maggie Fitzgerald |
| 2005 14. | Kadın Performansı | Uma Thurman | Kill Bill: Volume 2 | The Bride |
| 2006 15. | Best Performance (Combined) | Jake Gyllenhaal ‡ | Brokeback Mountain | Jack Twist |
| 2006 15. | Best Performance (Combined) | Steve Carell | The 40-Year-Old Virgin | Andy Stitzer |
| 2006 15. | Best Performance (Combined) | Terrence Howard ‡ | Hustle & Flow | DJay |
| 2006 15. | Best Performance (Combined) | Rachel McAdams | Red Eye | Lisa Reisert |
| 2006 15. | Best Performance (Combined) | Joaquin Phoenix ‡ | Walk the Line | Johnny Cash |
| 2006 15. | Best Performance (Combined) | Reese Witherspoon † | Walk the Line | June Carter Cash |
| 2007 16. | Best Performance (Combined) | Johnny Depp | Pirates of the Caribbean: Dead Man's Chest | Jack Sparrow |
| 2007 16. | Best Performance (Combined) | Gerard Butler | 300 | Leonidas |
| 2007 16. | Best Performance (Combined) | Jennifer Hudson ‡ | Dreamgirls | Effie White |
| 2007 16. | Best Performance (Combined) | Keira Knightley | Pirates of the Caribbean: Dead Man's Chest | Elizabeth |
| 2007 16. | Best Performance (Combined) | Beyoncé | Dreamgirls | Deena Jones |
| 2007 16. | Best Performance (Combined) | Will Smith ‡ | The Pursuit of Happyness | Chris Gardner |
| 2008 17. | Erkek Performansı | Will Smith | I Am Legend | Robert Neville |
| 2008 17. | Erkek Performansı | Michael Cera | Juno | Paulie Bleeker |
| 2008 17. | Erkek Performansı | Matt Damon | The Bourne Ultimatum | Jason Bourne |
| 2008 17. | Erkek Performansı | Shia LaBeouf | Transformers | Sam Witwicky |
| 2008 17. | Erkek Performansı | Denzel Washington | American Gangster | Frank Lucas |
| 2008 17. | Kadın Performansı | Ellen Page ‡ | Juno | Juno MacGuff |
| 2008 17. | Kadın Performansı | Amy Adams | Enchanted | Giselle |
| 2008 17. | Kadın Performansı | Jessica Biel | I Now Pronounce You Chuck and Larry | Alex McDonough |
| 2008 17. | Kadın Performansı | Katherine Heigl | Knocked Up | Alison Scott |
| 2008 17. | Kadın Performansı | Keira Knightley | Pirates of the Caribbean: At World's End | Elizabeth |
| 2009 18. | Erkek Performansı | Zac Efron | High School Musical 3: Senior Year | Troy Bolton |
| 2009 18. | Erkek Performansı | Christian Bale | The Dark Knight | Bruce Wayne / Batman |
| 2009 18. | Erkek Performansı | Vin Diesel | Fast & Furious | Dominic Toretto |
| 2009 18. | Erkek Performansı | Robert Downey, Jr. | Iron Man | Tony Stark / Iron Man |
| 2009 18. | Erkek Performansı | Shia LaBeouf | Eagle Eye | Jerry & Ethan Shaw |
| 2009 18. | Kadın Performansı | Kristen Stewart | Twilight | Bella Swan |
| 2009 18. | Kadın Performansı | Anne Hathaway | Bride Wars | Emma Allen |
| 2009 18. | Kadın Performansı | Taraji P. Henson ‡ | The Curious Case of Benjamin Button | Queenie |
| 2009 18. | Kadın Performansı | Angelina Jolie | Wanted | Fox |
| 2009 18. | Kadın Performansı | Kate Winslet † | The Reader | Hanna Schmitz |