EXO1
関連文献

“Is hEXO1 a cancer predisposing gene?”. Mol. Cancer Res. 2 (8):  427–32. (2005). doi:10.1158/1541-7786.427.2.8. PMID 15328369.
Holle GE (1985). “[Pathophysiology of ulcer disease]”. Langenbecks Archiv für Chirurgie 366:  81–7. doi:10.1007/bf01836609. PMID 2414623.
“Normalization and subtraction: two approaches to facilitate gene discovery.”. Genome Res. 6 (9):  791–806. (1997). doi:10.1101/gr.6.9.791. PMID 8889548.
“Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination.”. Cancer Res. 58 (22):  5027–31. (1998). PMID 9823303.
“Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance.”. J. Biol. Chem. 274 (25):  17893–900. (1999). doi:10.1074/jbc.274.25.17893. PMID 10364235.
“The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities.”. J. Biol. Chem. 274 (53):  37763–9. (2000). doi:10.1074/jbc.274.53.37763. PMID 10608837.
“Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis.”. Mutat. Res. 460 (1):  41–52. (2000). doi:10.1016/S0921-8777(00)00012-4. PMID 10856833.
“Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms.”. Gastroenterology 120 (7):  1580–7. (2001). doi:10.1053/gast.2001.25117. PMID 11375940.
“The interaction of DNA mismatch repair proteins with human exonuclease I.”. J. Biol. Chem. 276 (35):  33011–8. (2001). doi:10.1074/jbc.M102670200. PMID 11427529.
“HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes.”. Oncogene 20 (27):  3590–5. (2001). doi:10.1038/sj.onc.1204467. PMID 11429708.
“Human exonuclease I is required for 5' and 3' mismatch repair.”. J. Biol. Chem. 277 (15):  13302–11. (2002). doi:10.1074/jbc.M111854200. PMID 11809771.
“Molecular interactions of human Exo1 with DNA.”. Nucleic Acids Res. 30 (4):  942–9. (2002). doi:10.1093/nar/30.4.942. PMC 100345. PMID 11842105. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC100345/.
“Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.”. Cancer Res. 62 (21):  6026–30. (2002). PMID 12414623.
“Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26):  16899–903. (2003). Bibcode: 2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
“EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer.”. Cancer Res. 63 (1):  154–8. (2003). PMID 12517792.
“The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein.”. J. Biol. Chem. 278 (26):  23487–96. (2003). doi:10.1074/jbc.M212798200. PMID 12704184.
“Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability.”. Cancer Genet. Cytogenet. 147 (2):  121–7. (2004). doi:10.1016/S0165-4608(03)00196-1. PMID 14623461.
“Mechanism of 5'-directed excision in human mismatch repair.”. Mol. Cell 12 (5):  1077–86. (2004). doi:10.1016/S1097-2765(03)00428-3. PMID 14636568.
減数分裂時の組換えに関する現行のモデル。二本鎖切断（ギャップ）の形成によって開始され、続いて相同染色体との対合とstrand invasionによって組換え修復過程が開始される。ギャップの修復によって隣接領域に乗換えが生じる場合（CO）と生じない場合（NCO）がある。乗換え型組換えはダブルホリデイジャンクション（DHJ）モデルによって生じると考えられており、図の右側に示されている。非乗換え型組換えは主にSDSA（synthesis dependent strand annealing）モデルによって生じると考えられており、左側に示されている。組換えイベントの大部分はSDSA型のようである。