濡木理
代表的な論文

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Nureki, O. (1998). “Enzyme Structure with Two Catalytic Sites for Double-Sieve Selection of Substrate”. Science 280 (5363):  578–582. doi:10.1126/science.280.5363.578.
Handa, Noriko; Nureki, Osamu; Kurimoto, Kazuki; Kim, Insil; Sakamoto, Hiroshi; Shimura, Yoshiro; Muto, Yutaka; Yokoyama, Shigeyuki (1999). “Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein”. Nature 398 (6728):  579–585. doi:10.1038/19242.
Fukai, Shuya; Nureki, Osamu; Sekine, Shun-ichi; Shimada, Atsushi; Tao, Jianshi; Vassylyev, Dmitry G.; Yokoyama, Shigeyuki (2000). “Structural Basis for Double-Sieve Discrimination of L-Valine from L-Isoleucine and L-Threonine by the Complex of tRNAVal and Valyl-tRNA Synthetase”. Cell 103 (5):  793–803. doi:10.1016/S0092-8674(00)00182-3.
Ogiso, Hideo; Ishitani, Ryuichiro; Nureki, Osamu; Fukai, Shuya; Yamanaka, Mari; Kim, Jae-Hoon; Saito, Kazuki; Sakamoto, Ayako et al. (2002). “Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains”. Cell 110 (6):  775–787. doi:10.1016/S0092-8674(02)00963-7.
Ishitani, Ryuichiro; Nureki, Osamu; Nameki, Nobukazu; Okada, Norihiro; Nishimura, Susumu; Yokoyama, Shigeyuki (2003). “Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme”. Cell 113 (3):  383–394. doi:10.1016/S0092-8674(03)00280-0.
Tomita, Kozo; Fukai, Shuya; Ishitani, Ryuichiro; Ueda, Takuya; Takeuchi, Nono; Vassylyev, Dmitry G.; Nureki, Osamu (2004). “Structural basis for template-independent RNA polymerization”. Nature 430 (7000):  700–704. doi:10.1038/nature02712.
Numata, Tomoyuki; Ikeuchi, Yoshiho; Fukai, Shuya; Suzuki, Tsutomu; Nureki, Osamu (2006). “Snapshots of tRNA sulphuration via an adenylated intermediate”. Nature 442 (7101):  419–424. doi:10.1038/nature04896.
Tomita, Kozo; Ishitani, Ryuichiro; Fukai, Shuya; Nureki, Osamu (2006). “Complete crystallographic analysis of the dynamics of CCA sequence addition”. Nature 443 (7114):  956–960. doi:10.1038/nature05204.
Hattori, Motoyuki; Tanaka, Yoshiki; Fukai, Shuya; Ishitani, Ryuichiro; Nureki, Osamu (2007). “Crystal structure of the MgtE Mg2+ transporter”. Nature 448 (7157):  1072–1075. doi:10.1038/nature06093.
Tsukazaki, Tomoya; Mori, Hiroyuki; Fukai, Shuya; Ishitani, Ryuichiro; Mori, Takaharu; Dohmae, Naoshi; Perederina, Anna; Sugita, Yuji et al. (2008). “Conformational transition of Sec machinery inferred from bacterial SecYE structures”. Nature 455 (7215):  988–991. doi:10.1038/nature07421.
Nozawa, Kayo; O’Donoghue, Patrick; Gundllapalli, Sarath; Araiso, Yuhei; Ishitani, Ryuichiro; Umehara, Takuya; Söll, Dieter; Nureki, Osamu (2008). “Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality”. Nature 457 (7233):  1163–1167. doi:10.1038/nature07611.
Nakanishi, Kotaro; Bonnefond, Luc; Kimura, Satoshi; Suzuki, Tsutomu; Ishitani, Ryuichiro; Nureki, Osamu (2009). “Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase”. Nature 461 (7267):  1144–1148. doi:10.1038/nature08474.
Tsukazaki, Tomoya; Mori, Hiroyuki; Echizen, Yuka; Ishitani, Ryuichiro; Fukai, Shuya; Tanaka, Takeshi; Perederina, Anna; Vassylyev, Dmitry G. et al. (2011). “Structure and function of a membrane component SecDF that enhances protein export”. Nature 474 (7350):  235–238. doi:10.1038/nature09980.
Kato, Hideaki E.; Zhang, Feng; Yizhar, Ofer; Ramakrishnan, Charu; Nishizawa, Tomohiro; Hirata, Kunio; Ito, Jumpei; Aita, Yusuke et al. (2012). “Crystal structure of the channelrhodopsin light-gated cation channel”. Nature 482 (7385):  369–374. doi:10.1038/nature10870.
Nishimasu, Hiroshi; Ishizu, Hirotsugu; Saito, Kuniaki; Fukuhara, Satoshi; Kamatani, Miharu K.; Bonnefond, Luc; Matsumoto, Naoki; Nishizawa, Tomohiro et al. (2012). “Structure and function of Zucchini endoribonuclease in piRNA biogenesis”. Nature 491 (7423):  284–287. doi:10.1038/nature11509.
Tanaka, Yoshiki; Hipolito, Christopher J.; Maturana, Andrés D.; Ito, Koichi; Kuroda, Teruo; Higuchi, Takashi; Katoh, Takayuki; Kato, Hideaki E. et al. (2013). “Structural basis for the drug extrusion mechanism by a MATE multidrug transporter”. Nature 496 (7444):  247–251. doi:10.1038/nature12014.
Nishizawa, T.; Kita, S.; Maturana, A. D.; Furuya, N.; Hirata, K.; Kasuya, G.; Ogasawara, S.; Dohmae, N. et al. (2013). “Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger”. Science 341 (6142):  168–172. doi:10.1126/science.1239002.
Nishimasu, Hiroshi; Ran, F. Ann; Hsu, Patrick D.; Konermann, Silvana; Shehata, Soraya I.; Dohmae, Naoshi; Ishitani, Ryuichiro; Zhang, Feng et al. (2014). “Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA”. Cell 156 (5):  935–949. doi:10.1016/j.cell.2014.02.001.
Kumazaki, Kaoru; Chiba, Shinobu; Takemoto, Mizuki; Furukawa, Arata; Nishiyama, Ken-ichi; Sugano, Yasunori; Mori, Takaharu; Dohmae, Naoshi et al. (2014). “Structural basis of Sec-independent membrane protein insertion by YidC”. Nature 509 (7501):  516–520. doi:10.1038/nature13167.
Kato, Hideaki E.; Inoue, Keiichi; Abe-Yoshizumi, Rei; Kato, Yoshitaka; Ono, Hikaru; Konno, Masae; Hososhima, Shoko; Ishizuka, Toru et al. (2015). “Structural basis for Na+ transport mechanism by a light-driven Na+ pump”. Nature 521 (7550):  48–53. doi:10.1038/nature14322.
Nishimasu, Hiroshi; Cong, Le; Yan, Winston X.; Ran, F. Ann; Zetsche, Bernd; Li, Yinqing; Kurabayashi, Arisa; Ishitani, Ryuichiro et al. (2015). “Crystal Structure of Staphylococcus aureus Cas9”. Cell 162 (5):  1113–1126. doi:10.1016/j.cell.2015.08.007.
Hirano, Hisato; Gootenberg, Jonathan S.; Horii, Takuro; Abudayyeh, Omar O.; Kimura, Mika; Hsu, Patrick D.; Nakane, Takanori; Ishitani, Ryuichiro et al. (2016). “Structure and Engineering of Francisella novicida Cas9”. Cell 164 (5):  950–961. doi:10.1016/j.cell.2016.01.039.
Tsuchiya, Hirotoshi; Doki, Shintaro; Takemoto, Mizuki; Ikuta, Tatsuya; Higuchi, Takashi; Fukui, Keita; Usuda, Yoshihiro; Tabuchi, Eri et al. (2016). “Structural basis for amino acid export by DMT superfamily transporter YddG”. Nature 534 (7607):  417–420. doi:10.1038/nature17991.
Yamano, Takashi; Nishimasu, Hiroshi; Zetsche, Bernd; Hirano, Hisato; Slaymaker, Ian M.; Li, Yinqing; Fedorova, Iana; Nakane, Takanori et al. (2016). “Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA”. Cell 165 (4):  949–962. doi:10.1016/j.cell.2016.04.003.
Shihoya, Wataru; Nishizawa, Tomohiro; Okuta, Akiko; Tani, Kazutoshi; Dohmae, Naoshi; Fujiyoshi, Yoshinori; Nureki, Osamu; Doi, Tomoko (2016). “Activation mechanism of endothelin ETB receptor by endothelin-1”. Nature 537 (7620):  363–368. doi:10.1038/nature19319.
Matsumoto, Naoki; Nishimasu, Hiroshi; Sakakibara, Kazuhiro; Nishida, Kazumichi M.; Hirano, Takamasa; Ishitani, Ryuichiro; Siomi, Haruhiko; Siomi, Mikiko C. et al. (2016). “Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA”. Cell 167 (2):  484–497.e9. doi:10.1016/j.cell.2016.09.002.
Taniguchi, Reiya; Inoue, Asuka; Sayama, Misa; Uwamizu, Akiharu; Yamashita, Keitaro; Hirata, Kunio; Yoshida, Masahito; Tanaka, Yoshiki et al. (2017). “Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6”. Nature 548 (7667):  356–360. doi:10.1038/nature23448.
Nishimasu, Hiroshi; Shi, Xi; Ishiguro, Soh; Gao, Linyi; Hirano, Seiichi; Okazaki, Sae; Noda, Taichi; Abudayyeh, Omar O. et al. (2018). “Engineered CRISPR-Cas9 nuclease with expanded targeting space”. Science 361 (6408):  1259–1262. doi:10.1126/science.aas9129.
Akichika, Shinichiro; Hirano, Seiichi; Shichino, Yuichi; Suzuki, Takeo; Nishimasu, Hiroshi; Ishitani, Ryuichiro; Sugita, Ai; Hirose, Yutaka et al. (2019). “Cap-specific terminal N6-methylation of RNA by an RNA polymerase II–associated methyltransferase”. Science 363 (6423):  eaav0080. doi:10.1126/science.aav0080. ISSN 0036-8075.
Hiraizumi, Masahiro; Yamashita, Keitaro; Nishizawa, Tomohiro; Nureki, Osamu (2019). “Cryo-EM structures capture the transport cycle of the P4-ATPase flippase”. Science 365 (6458):  1149–1155. doi:10.1126/science.aay3353. ISSN 0036-8075.
Shihoya, Wataru; Inoue, Keiichi; Singh, Manish; Konno, Masae; Hososhima, Shoko; Yamashita, Keitaro; Ikeda, Kento; Higuchi, Akimitsu et al. (2019). “Crystal structure of heliorhodopsin”. Nature 574 (7776):  132–136. doi:10.1038/s41586-019-1604-6. ISSN 0028-0836.
Kise, Yoshiaki; Kasuya, Go; Okamoto, Hiroyuki H.; Yamanouchi, Daichi; Kobayashi, Kan; Kusakizako, Tsukasa; Nishizawa, Tomohiro; Nakajo, Koichi et al. (2021). “CrystalStructural basis of gating modulation of Kv4 channel complexes”. Nature 599 (7883):  158–164. doi:10.1038/s41586-021-03935-z. ISSN 0028-0836.
Yamaguchi, Sonomi; Naganuma, Masahiro; Nishizawa, Tomohiro; Kusakizako, Tsukasa; Tomari, Yukihide; Nishimasu, Hiroshi; Nureki, Osamu (2022). “Structure of the Dicer-2–R2D2 heterodimer bound to a small RNA duplex”. Nature 607 (7916):  393–398. doi:10.1038/s41586-022-04790-2. ISSN 0028-0836.
Chazan, Ariel; Das, Ishita; Fujiwara, Takayoshi; Murakoshi, Shunya; Rozenberg, Andrey; Molina-Márquez, Ana; Sano, Fumiya K.; Tanaka, Tatsuki et al. (2023). “Phototrophy by antenna-containing rhodopsin pumps in aquatic environments”. Nature 615 (7950):  535–540. doi:10.1038/s41586-023-05774-6. ISSN 0028-0836.