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"Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB" M Hagiwara, A Alberts, P Brindle, J Meinkoth, J Feramisco, T Deng, M Karin, S Shenolikar, M Montminy. Cell. 1992;70:105-113., PMID 1352481, doi:10.1016/0092-8674(92)90537-m
"Phosphorylated CREB binds specifically to the nuclear protein CBP" J C Chrivia, R P Kwok, N Lamb, M Hagiwara, M R Montminy, R H Goodman. Nature. 1993;365:855-859., PMID 8413673, doi:10.1038/365855a0
"A fluorescent indicator for visualizing cAMP-induced phosphorylation in vivo" Y Nagai, M Miyazaki, R Aoki, T Zama, S Inouye, K Hirose, M Iino, M Hagiwara. Nat Biotechnol. 2000;18:313-316., PMID 10700148, doi:10.1038/73767
"Transgenic alternative-splicing reporters reveal tissue-specific expression profiles and regulation mechanisms in vivo" H Kuroyanagi, T Kobayashi, S Mitani, M Hagiwara. Nat Methods. 2006;3:909-915., PMID 17060915, doi:10.1038/nmeth944
"Visualization and genetic analysis of alternative splicing regulation in vivo using fluorescence reporters in transgenic Caenorhabditis elegans" H Kuroyanagi, G Ohno, H Sakane, H Maruoka, M Hagiwara. Nat Protoc. 2010;5:1495-1517., PMID 20725066, doi:10.1038/nprot.2010.107
"Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A" Y Ogawa, Y Nonaka, T Goto, E Ohnishi, T Hiramatsu, I Kii, M Yoshida, T Ikura, H Onogi, H Shibuya, T Hosoya, N Ito, M Hagiwara. Nat Commun. 2010;1:86., PMID 20981014, doi:10.1038/ncomms1090
"Chemical treatment enhances skipping of a mutated exon in the dystrophin gene" A Nishida, N Kataoka, Y Takeshima, M Yagi, H Awano, M Ota, K Itoh, M Hagiwara, M Matsuo. Nat Commun. 2011;2:308., PMID 21556062, doi:10.1038/ncomms1306
"CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses" M Yamamoto, H Onogi, I Kii, S Yoshida, K Iida, H Sakai, M Abe, T Tsubota, N Ito, T Hosoya, M Hagiwara. J Clin Invest. 2014;124:3479-3488., PMID 25003190, doi:10.1172/JCI73805
"Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia" M Yoshida, N Kataoka, K Miyauchi, K Ohe, K Iida, S Yoshida, T Nojima, Y Okuno, H Onogi, T Usui, A Takeuchi, T Hosoya, T Suzuki, M Hagiwara.  Proc Natl Acad Sci U S A. 2015;112:2764-2769., PMID 25675486, doi:10.1073/pnas.1415525112
"Prenatal neurogenesis induction therapy normalizes brain structure and function in Down syndrome mice" A Nakano-Kobayashi, T Awaya, I Kii, Y Sumida, Y Okuno, S Yoshida, T Sumida, H Inoue, T Hosoya, M Hagiwara. Proc Natl Acad Sci U S A. 2017;114:10268-10273., PMID 28874550, doi:10.1073/pnas.1704143114
"CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has a Therapeutic Effect on HPV-Induced Neoplasia" M Ajiro, H Sakai, H Onogi, M Yamamoto, E Sumi, T Sawada, T Nomura, K Kabashima, T Hosoya, M Hagiwara. Clin Cancer Res. 2018;24:4518-4528., PMID 29712686, doi:10.1158/1078-0432.CCR-17-3119
"Mechanism-Based Personalized Medicine for Cystic Fibrosis by Suppressing Pseudo Exon Inclusion" S Shibata, M Ajiro, M Hagiwara. Cell Chem Biol. 2020;27:1472-1482.e6., PMID 32905759, doi:10.1016/j.chembiol.2020.08.013
"Therapeutics potentiating microglial p21-Nrf2 axis can rescue neurodegeneration caused by neuroinflammation" A Nakano-Kobayashi, A Fukumoto, A Morizane, D T Nguyen, T M Le, K Hashida, T Hosoya, R Takahashi, J Takahashi, O Hori, M Hagiwara. Sci Adv. 2020;6:eabc1428., PMID 33188020, doi:10.1126/sciadv.abc1428
"Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia" M Ajiro, T Awaya, Y J Kim, K Iida, M Denawa, N Tanaka, R Kurosawa, S Matsushima, S Shibata, T Sakamoto, L Studer, A R Krainer, M Hagiwara. Nat Commun. 2021;12:4507., PMID 34301951, doi:10.1038/s41467-021-24705-5
"Chemical induction of splice-neoantigens attenuates tumor growth in a preclinical model of colorectal cancer" S Matsushima, M Ajiro, K Iida, K Chamoto, T Honjo, M Hagiwara. Sci Transl Med. 2022;14:eabn6056., PMID 36449604, doi:10.1126/scitranslmed.abn6056