RAD50
関連文献

“The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together”. DNA Repair (Amst.) 3 (8–9):  845–54. (2005). doi:10.1016/j.dnarep.2004.03.014. PMID 15279769.
Dolganov GM; Maser RS; Novikov A et al. (1996). “Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair”. Mol. Cell. Biol. 16 (9):  4832–41. doi:10.1128/MCB.16.9.4832. PMC 231485. PMID 8756642. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC231485/.
“hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks”. Mol. Cell. Biol. 17 (10):  6087–96. (1997). doi:10.1128/MCB.17.10.6087. PMC 232458. PMID 9315668. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC232458/.
Carney JP; Maser RS; Olivares H et al. (1998). “The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response”. Cell 93 (3):  477–86. doi:10.1016/S0092-8674(00)81175-7. PMID 9590181.
“The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks”. Mol. Cell 1 (7):  969–79. (1998). doi:10.1016/S1097-2765(00)80097-0. PMID 9651580.
“Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95”. J. Biol. Chem. 273 (34):  21447–50. (1998). doi:10.1074/jbc.273.34.21447. PMID 9705271.
“Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex”. Genes Dev. 13 (10):  1276–88. (1999). doi:10.1101/gad.13.10.1276. PMC 316715. PMID 10346816. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316715/.
Kim KK; Shin BA; Seo KH et al. (1999). “Molecular cloning and characterization of splice variants of human RAD50 gene”. Gene 235 (1–2):  59–67. doi:10.1016/S0378-1119(99)00215-2. PMID 10415333.
Zhong Q; Chen CF; Li S et al. (1999). “Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response”. Science 285 (5428):  747–50. doi:10.1126/science.285.5428.747. PMID 10426999.
Wang Y; Cortez D; Yazdi P et al. (2000). “BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures”. Genes Dev. 14 (8):  927–39. doi:10.1101/gad.14.8.927. PMC 316544. PMID 10783165. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316544/.
Gatei M; Young D; Cerosaletti KM et al. (2000). “ATM-dependent phosphorylation of nibrin in response to radiation exposure”. Nat. Genet. 25 (1):  115–9. doi:10.1038/75508. PMID 10802669.
Zhao S; Weng YC; Yuan SS et al. (2000). “Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products”. Nature 405 (6785):  473–7. Bibcode: 2000Natur.405..473Z. doi:10.1038/35013083. PMID 10839544.
Zhu XD; Küster B; Mann M et al. (2000). “Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres”. Nat. Genet. 25 (3):  347–52. doi:10.1038/77139. PMID 10888888.
Paull TT; Rogakou EP; Yamazaki V et al. (2001). “A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage”. Curr. Biol. 10 (15):  886–95. doi:10.1016/S0960-9822(00)00610-2. PMID 10959836.
“RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control”. J. Biol. Chem. 276 (9):  6105–11. (2001). doi:10.1074/jbc.M008893200. PMID 11096100.
“Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization”. Mol. Cell. Biol. 21 (6):  2184–91. (2001). doi:10.1128/MCB.21.6.2184-2191.2001. PMC 86852. PMID 11238951. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC86852/.
Buscemi G; Savio C; Zannini L et al. (2001). “Chk2 activation dependence on Nbs1 after DNA damage”. Mol. Cell. Biol. 21 (15):  5214–22. doi:10.1128/MCB.21.15.5214-5222.2001. PMC 87245. PMID 11438675. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC87245/.
“Redistribution of BRCA1 among four different protein complexes following replication blockage”. J. Biol. Chem. 276 (42):  38549–54. (2001). doi:10.1074/jbc.M105227200. PMID 11504724.
“Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex”. Nat. Cell Biol. 3 (9):  844–7. (2001). doi:10.1038/ncb0901-844. PMID 11533665.
de Jager M; van Noort J; van Gent DC et al. (2002). “Human Rad50/Mre11 is a flexible complex that can tether DNA ends”. Mol. Cell 8 (5):  1129–35. doi:10.1016/S1097-2765(01)00381-1. PMID 11741547.
M. Beikzadeh, M.P. Latham (2020). “The dynamic nature of the Mre11-Rad50 DNA break repair complex”. Progress in Biophysics and Molecular Biology 163:  14–22. doi:10.1016/j.pbiomolbio.2020.10.007. PMC 8065065. PMID 33121960. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065065/.