北村俊雄
主な論文

代表論文として次のものを含む。
Fujino, T., Goyama, S., Sugiura, Y., Inoue, D., Asada, S., Yamasaki, S., Matsumoto, A., Tsuchiya, A., Shikata, S., Sato N., Morinaga, H., Fukuyama, T., Tanaka, Y., Fukushima, T., Takeda, R., Yamamoto, K., Honda, H., Nishimura, E.K., Shibata, T., Abdel-Wahab, Omar., Suematsu, M., and Kitamura, T. (2020) Mutant ASXL1 induces clonal hematopoiesis through activation of Akt/mTOR pathway. Nat Commun in press.
Takeda, R., Asada, S., Park, SJ., Yokoyama, A., Becker, HJ., Kanai, A., Visconte, V.,  Hershberger, C., Hayashi, Y., Yonezawa, T., Tamura, M., Fukushima, T., Tanaka, Y., Fukuyama, Matsumoto, A., Yamasaki, S., Nakai, K., Yamazaki, S., Inaba, T., Shibata, T., Inoue, D., Honda, H., Goyama, S., Maciejewski, JP., and Kitamura, T. (2020) HHEX promotes myeloid transformation in cooperation with mutant ASXL1. Blood in press.
Hayashi, Y., Goyama, S., Liu, XX, Asada, S., Tanaka, Y., Fukuyama, T., Wunderlich, M., O’Brien, E., Mizukawa, B., Yamazaki, S., Matsumoto, A. Yamasaki, S., Shibata, T., Matsuda, K., Sashida, G., Takizawa, H., and Kitamura, T. (2019) Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia. Nat Commun 10:4869.
Fukushima, T., Tanaka, Y., Hamey, F.K., Chang, C-H., Oki, T., Asada, S., Hayashi, Y., Fujino, T., Yonezawa, T., Takeda, R., Kawabata, K.C., Fukuyama, T., Umemoto, T., Takubo, K., Takizawa, H., Goyama, S., Ishihama, Y., Honda, H., Gottgens, B., and Kitamura, T. (2019) Discrimination of dormant and active hematopoietic stem cells by G0 markers reveals dormancy regulation by cytoplasmic calcium. Cell Rep 12:4144-4158.
Nagase, R., Inoue, D., Pastre, A., Fujino, T., Hou, H-A, Yamasaki,N., Goyama, S., Saika, M., Kanai, A., Sera, Y., Horikawa, S., Ota, Y., Asada, S., Hayashi, Y., Kawabata, K.C., Takeda, R., Tien, H.F., Honda, H., Abdel-Wahab, O. and Kitamura, T. (2018) Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation. J Exp Med 215:1729-1747.
Asada, S., Goyama, S., Inoue, D., Shikata, S., Takeda, R., Fukushima, T., Yonezawa, T., Fujino, T., Hayashi, Y., Kawabata, K.C., Fukuyama, T., Tanaka, Y., Yokoyama, A., Yamazaki, S., Kozuka-Hata, H., Oyama, M., Kojima, S., Kawazu, M., Mano, H., and Kitamura, T. (2018) Mutant ASXL1 cooperates with BAP1 to promote myeloid leukemogenesis. Nat Commun 9:2733.
Inoue, D., Kitaura, J., Togami, K., Nishimura, K., Enomoto, Y., Uchida, T., Kagiyama, Y., Kawabata, K.C., Nakahara, F., Izawa, K., Oki, T., Maehara, A., Isobe, M., Tsuchiya, A., Harada, Y., Harada, H., Ochiya, T., Aburatani, H., Kimura, H., Thol, F., Heuser, M., Levine, R.L., Abdel-Wahab, O. and Kitamura, T. (2013) Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations. J Clin Invest 123:4627-4640.
Yamanishi, Y., Kitaura, J., Izawa, K., Kaitani, A., Komeno, Y., Nakamura, M., Yamazaki, S., Enomoto, Y., Oki, T., Akiba, H., Komori, T., Morikawa, Y., Kiyonari, H., Takai, T., Okumura, K., and Kitamura, T. (2010) TIM1 is an endogenous ligand for LMIR5/CD300b and LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury. J Exp Med 207:1501-1511.
Kawashima, T., Bao, Y.C., Nomura, Y., Moon, Y., Tonozuka, Y., Minoshima, Y., Hatori, T., Kiyono, M., Nosaka, T., Nakajima, H., Williams, D.A., and Kitamura, T. (2006) Rac1 and a GTPase activating protein MgcRacGAP are required for nuclear translocation of STAT transcription factors. J Cell Biol 175: 937-946.
Ikeda, Y., Imai, Y., Kumagai, H., Nosaka, T., Morikawa, Y., Hisaoka, T., Manabe, I., Maemura, K., Nakaoka, T., Imamura, T., Miyazono, K., Komuro, I., Nagai, R. and Kitamura, T. (2004) Vasorin, a novel TGF-β binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo. Proc Natl Acad Sci USA 101:10732-10737.
Minoshima, Y., Kawashima, T., Hirose, K., Tonozuka, Y., Kawajiri, A., Bao, Y-C., Deng, X., Tatsuka, M., Narumiya, S., May, W.S. Jr., Nosaka, T., Senba, K., Inoue, T., Satoh, T., Inagaki, M., and Kitamura, T. (2003) Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell 4:549-560.
Misawa, K., Nosaka, T., Morita, S., Kaneko, A., Nakahata, T., Asano, S. and Kitamura, T. (2000) A method to identify cDNAs based on localization of green fluorescent protein fusion products. Proc Natl Acad Sci USA 97:3062-3066.
Kojima, T., and Kitamura, T. (1999) A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotech 17: 487-490.
Onishi, M., Nosaka, T., Misawa, K., Mui, A.L.-F., Gorman, D., McMahon, M., Miyajima, A., and Kitamura, T. (1998) Identification and characterization of a constitutive active STAT5 mutant that promotes cell proliferation. Mol Cell Biol 18:3871-3879.
Kitamura, T., Onishi, M., Kinoshita, S., Shibuya, A., Miyajima, A., and Nolan, G.P. (1995) Efficient screening of retroviral cDNA expression libraries. Proc Natl Acad Sci USA 92: 9146-9150.
Kitamura, T., Hayashida, K., Sakamaki, K., Yokota, T., Arai, K. and Miyajima, A. (1991) Reconstitution of functional human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that AIC2B is a subunit of murine GM-CSF receptor. Proc Natl Acad Sci USA 88: 5082-5086.
Kitamura, T., Sato, N., Arai, K. and Miyajima, A. (1991) Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 66: 1165-1174.