ERN1
関連文献

“Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response”. Nature Cell Biology 1 (8):  479–485. (December 1999). doi:10.1038/70265. PMID 10587643.
“Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1”. Science 287 (5453):  664–666. (January 2000). Bibcode: 2000Sci...287..664U. doi:10.1126/science.287.5453.664. PMID 10650002.
“Shotgun sequencing of the human transcriptome with ORF expressed sequence tags”. Proceedings of the National Academy of Sciences of the United States of America 97 (7):  3491–3496. (March 2000). Bibcode: 2000PNAS...97.3491D. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC16267/.
“Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress”. Nature Cell Biology 3 (2):  158–164. (February 2001). doi:10.1038/35055065. PMID 11175748.
“Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress”. The Journal of Biological Chemistry 276 (17):  13935–13940. (April 2001). doi:10.1074/jbc.M010677200. PMID 11278723.
“IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response”. Genes & Development 16 (4):  452–466. (February 2002). doi:10.1101/gad.964702. PMC 155339. PMID 11850408. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155339/.
“The protein kinase/endoribonuclease IRE1alpha that signals the unfolded protein response has a luminal N-terminal ligand-independent dimerization domain”. The Journal of Biological Chemistry 277 (21):  18346–18356. (May 2002). doi:10.1074/jbc.M112454200. PMID 11897784.
“ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats”. Genes & Development 16 (11):  1345–1355. (June 2002). doi:10.1101/gad.992302. PMC 186318. PMID 12050113. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC186318/.
“Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha”. Molecular and Cellular Biology 22 (24):  8506–8513. (December 2002). doi:10.1128/MCB.22.24.8506-8513.2002. PMC 139892. PMID 12446770. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139892/.
“Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proceedings of the National Academy of Sciences of the United States of America 99 (26):  16899–16903. (December 2002). Bibcode: 2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
“Structure and intermolecular interactions of the luminal dimerization domain of human IRE1alpha”. The Journal of Biological Chemistry 278 (20):  17680–17687. (May 2003). doi:10.1074/jbc.M300418200. PMID 12637535.
“Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2”. Biological & Pharmaceutical Bulletin 26 (7):  931–935. (July 2003). doi:10.1248/bpb.26.931. PMID 12843613.
“Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nature Genetics 36 (1):  40–45. (January 2004). doi:10.1038/ng1285. PMID 14702039.
“Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts”. Biochemical and Biophysical Research Communications 317 (2):  390–396. (April 2004). doi:10.1016/j.bbrc.2004.03.058. PMID 15063770.
“JAB1 participates in unfolded protein responses by association and dissociation with IRE1”. Neurochemistry International 45 (5):  765–772. (October 2004). doi:10.1016/j.neuint.2004.01.003. PMID 15234121.
“Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress”. Molecular and Cellular Biology 25 (17):  7522–7533. (September 2005). doi:10.1128/MCB.25.17.7522-7533.2005. PMC 1190304. PMID 16107700. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190304/.
“Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes”. Genome Research 16 (1):  55–65. (January 2006). doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129/.
“Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha”. Science 312 (5773):  572–576. (April 2006). Bibcode: 2006Sci...312..572H. doi:10.1126/science.1123480. PMID 16645094.
“Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1”. Biochemical and Biophysical Research Communications 360 (1):  122–127. (August 2007). doi:10.1016/j.bbrc.2007.06.020. PMID 17585877.