アクアポリン
参考

↑  Agre P (2006). “The aquaporin water channels”. Proc Am Thorac Soc 3 (1):  5–13. doi:10.1513/pats.200510-109JH. PMID 16493146.
↑  Agre P, Kozono D (2003). “Aquaporin water channels: molecular mechanisms for human diseases”. FEBS Lett. 555 (1):  72–8. doi:10.1016/S0014-5793(03)01083-4. PMID 14630322.
↑  Schrier RW (2007). “Aquaporin-related disorders of water homeostasis”. Drug News Perspect. 20 (7):  447–53. doi:10.1358/dnp.2007.20.7.1138161. PMID 17992267.
↑  Knepper MA, Nielsen S (2004). “Peter Agre, 2003 Nobel Prize winner in chemistry”. J. Am. Soc. Nephrol. 15 (4):  1093–5. doi:10.1097/01.ASN.0000118814.47663.7D. PMID 15034115.
1 2  “The Nobel Prize in Chemistry 2003”.   Nobel Foundation. 2008年1月23日閲覧。
1 2  Gonen T, Walz T (2006). “The structure of aquaporins”. Q. Rev. Biophys. 39 (4):  361–96. doi:10.1017/S0033583506004458. PMID 17156589.
↑  Kruse E, Uehlein N, Kaldenhoff R (2006). “The aquaporins”. Genome Biol. 7 (2):  206. doi:10.1186/gb-2006-7-2-206. PMID 16522221.
↑  Agre P, Preston GM, Smith BL, Jung JS, Raina S, Moon C, Guggino WB, Nielsen S (1993). “Aquaporin CHIP: the archetypal molecular water channel”. Am. J. Physiol. 265 (4 Pt 2):  F463–76. PMID 7694481. http://ajprenal.physiology.org/cgi/content/abstract/265/4/F463.
↑  Mitsuoka K, Murata K, Walz T, Hirai T, Agre P, Heymann JB, Engel A, Fujiyoshi Y (1999). “The structure of aquaporin-1 at 4.5-A resolution reveals short alpha-helices in the center of the monomer”. J. Struct. Biol. 128 (1):  34–43. doi:10.1006/jsbi.1999.4177. PMID 10600556.
↑  de Groot BL, Grubmüller H (2005). “The dynamics and energetics of water permeation and proton exclusion in aquaporins”. Curr. Opin. Struct. Biol. 15 (2):  176–83. doi:10.1016/j.sbi.2005.02.003. PMID 15837176.
↑  Fu D, Lu M (2007). “The structural basis of water permeation and proton exclusion in aquaporins”. Mol. Membr. Biol. 24 (5-6):  366–74. doi:10.1080/09687680701446965. PMID 17710641.
↑  Tajkhorshid E, Nollert P, Jensen MØ, Miercke LJ, O'Connell J, Stroud RM, Schulten K (2002). “Control of the selectivity of the aquaporin water channel family by global orientational tuning”. Science 296 (5567):  525–30. doi:10.1126/science.1067778. PMID 11964478.
↑  Nielsen S, Frøkiaer J, Marples D, Kwon TH, Agre P, Knepper MA (2002). “Aquaporins in the kidney: from molecules to medicine”. Physiol. Rev. 82 (1):  205–44. doi:10.1152/physrev.00024.2001. PMID 11773613.
1 2  Unless else specified in table boxes, then ref is：Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3  Page 842
↑  Kaldenhoff R, Bertl A, Otto B, Moshelion M, Uehlein N (2007). “Characterization of plant aquaporins”. Meth. Enzymol. 428:  505–31. doi:10.1016/S0076-6879(07)28028-0. PMID 17875436.
↑  Maeshima M (2001). “TONOPLAST TRANSPORTERS: Organization and Function”. Annu Rev Plant Physiol Plant Mol Biol 52:  469–497. doi:10.1146/annurev.arplant.52.1.469. PMID 11337406.
↑  Wallace IS, Choi WG, Roberts DM (2006). “The structure, function and regulation of the nodulin 26-like intrinsic protein family of plant aquaglyceroporins”. Biochim. Biophys. Acta 1758 (8):  1165–75. doi:10.1016/j.bbamem.2006.03.024. PMID 16716251.
↑  Johanson U, Gustavsson S (2002). “A new subfamily of major intrinsic proteins in plants”. Mol. Biol. Evol. 19 (4):  456–61. PMID 11919287. http://mbe.oxfordjournals.org/cgi/content/abstract/19/4/456.
アクアポリン1（AQP1）の2D概略図
6個のαヘリックスと5個のヘリックス間ループが存在する
アクアポリンの3D構造
漏斗状構造により水分子などを通過させることができる
アクアポリンによる水の取り込みの概念図