LKB1
関連文献

“LKB1--a master tumour suppressor of the small intestine and beyond”. Nature Reviews. Cancer 2 (7):  529–35. (July 2002). doi:10.1038/nrc843. PMID 12094239.
“LKB1 tumor suppressor protein: PARtaker in cell polarity”. Trends in Cell Biology 14 (6):  312–9. (June 2004). doi:10.1016/j.tcb.2004.04.001. PMID 15183188.
“The LKB1 tumor suppressor kinase in human disease”. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1775 (1):  63–75. (January 2007). doi:10.1016/j.bbcan.2006.08.003. PMID 17010524.
“Normalization and subtraction: two approaches to facilitate gene discovery”. Genome Research 6 (9):  791–806. (September 1996). doi:10.1101/gr.6.9.791. PMID 8889548.
“Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer”. Cancer Research 58 (7):  1384–6. (April 1998). PMID 9537235.
“Nine novel germline mutations of STK11 in ten families with Peutz-Jeghers syndrome”. Human Genetics 103 (2):  168–72. (August 1998). doi:10.1007/s004390050801. PMID 9760200.
“Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity”. American Journal of Human Genetics 63 (6):  1641–50. (December 1998). doi:10.1086/302159. PMC 1377635. PMID 9837816. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1377635/.
“Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma”. Oncogene 18 (9):  1777–80. (March 1999). doi:10.1038/sj.onc.1202486. PMID 10208439.
“Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers”. The American Journal of Pathology 154 (6):  1835–40. (June 1999). doi:10.1016/S0002-9440(10)65440-5. PMC 1866632. PMID 10362809. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866632/.
“Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families”. Human Mutation 13 (6):  476–81. (1999). doi:10.1002/(SICI)1098-1004(1999)13:6<476::AID-HUMU7>3.0.CO;2-2. PMID 10408777.
“Antigens recognized by autologous antibody in patients with renal-cell carcinoma”. International Journal of Cancer 83 (4):  456–64. (November 1999). doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
“LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo”. The Biochemical Journal 345 Pt 3 (3):  673–80. (February 2000). doi:10.1042/0264-6021:3450673. PMC 1220803. PMID 10642527. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1220803/.
“Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth”. The Journal of Biological Chemistry 276 (22):  19469–82. (June 2001). doi:10.1074/jbc.M009953200. PMID 11297520.
“The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death”. Molecular Cell 7 (6):  1307–19. (June 2001). doi:10.1016/S1097-2765(01)00258-1. PMID 11430832.
“Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene”. Oncogene 23 (22):  4037–40. (May 2004). doi:10.1038/sj.onc.1207502. PMID 15021901.
“Mutation screening at the RNA level of the STK11/LKB1 gene in Peutz-Jeghers syndrome reveals complex splicing abnormalities and a novel mRNA isoform (STK11 c.597(insertion mark)598insIVS4)”. Human Mutation 18 (5):  397–410. (November 2001). doi:10.1002/humu.1211. PMID 11668633.
“STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas”. The American Journal of Pathology 159 (6):  2017–22. (December 2001). doi:10.1016/S0002-9440(10)63053-2. PMC 1850608. PMID 11733352. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850608/.