PDX1
関連文献

“In vivo reprogramming of adult pancreatic exocrine cells to β-cells”. Nature 455 (7213):  627–32. (2008). Bibcode: 2008Natur.455..627Z. doi:10.1038/nature07314. PMC 9011918. PMID 18754011. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011918/.
“Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood.”. Eur. J. Endocrinol. 146 (2):  129–41. (2002). doi:10.1530/eje.0.1460129. PMID 11834421.
“Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.”. Mol. Endocrinol. 7 (10):  1275–83. (1994). doi:10.1210/mend.7.10.7505393. PMID 7505393.
“Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1.”. Genomics 28 (1):  125–6. (1995). doi:10.1006/geno.1995.1120. PMID 7590740.
“Isolation, characterization, and chromosomal mapping of the human insulin promoter factor 1 (IPF-1) gene.”. Diabetes 45 (6):  789–94. (1996). doi:10.2337/diabetes.45.6.789. PMID 8635654.
“Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor.”. Mol. Endocrinol. 10 (11):  1327–34. (1997). doi:10.1210/mend.10.11.8923459. PMID 8923459.
“Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription.”. Biochem. Biophys. Res. Commun. 229 (3):  746–51. (1997). doi:10.1006/bbrc.1996.1875. PMID 8954967.
“Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells.”. Proc. Natl. Acad. Sci. U.S.A. 93 (26):  15057–62. (1997). doi:10.1073/pnas.93.26.15057. PMC 26355. PMID 8986763. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC26355/.
“Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence.”. Nat. Genet. 15 (1):  106–10. (1997). doi:10.1038/ng0197-106. PMID 8988180.
“Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1.”. Mol. Cell. Biol. 17 (5):  2598–604. (1997). doi:10.1128/mcb.17.5.2598. PMC 232109. PMID 9111329. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC232109/.
“Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells.”. J. Biol. Chem. 272 (18):  11986–93. (1997). doi:10.1074/jbc.272.18.11986. PMID 9115263.
“The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells.”. J. Biol. Chem. 272 (33):  20936–44. (1997). doi:10.1074/jbc.272.33.20936. PMID 9252422.
“Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes.”. J. Clin. Invest. 104 (9):  R33–9. (1999). doi:10.1172/JCI7449. PMC 481047. PMID 10545530. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC481047/.
“Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus.”. J. Clin. Invest. 104 (9):  R41–8. (1999). doi:10.1172/JCI7469. PMC 409821. PMID 10545531. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC409821/.
“Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter.”. J. Biol. Chem. 275 (3):  2199–204. (2000). doi:10.1074/jbc.275.3.2199. PMID 10636926.
“Pancreatic homeodomain transcription factor IDX1/IPF1 expressed in developing brain regulates somatostatin gene transcription in embryonic neural cells.”. J. Biol. Chem. 275 (25):  19106–14. (2000). doi:10.1074/jbc.M000655200. PMID 10751390.
“DNA cloning using in vitro site-specific recombination.”. Genome Res. 10 (11):  1788–95. (2001). doi:10.1101/gr.143000. PMC 310948. PMID 11076863. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310948/.
“DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex.”. J. Biol. Chem. 276 (21):  17985–93. (2001). doi:10.1074/jbc.M100678200. PMID 11279116.
“Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6.”. Mol. Cell. Biol. 22 (13):  4702–13. (2002). doi:10.1128/MCB.22.13.4702-4713.2002. PMC 133887. PMID 12052878. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133887/.
“Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors.”. J. Cell. Physiol. 192 (3):  304–14. (2002). doi:10.1002/jcp.10143. PMID 12124776. https://zenodo.org/record/1229235.