インターロイキン-21
関連文献

“Interleukin-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses”. Immunology 112 (2):  177–82. (June 2004). doi:10.1111/j.1365-2567.2004.01886.x. PMC 1782493. PMID 15147560. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782493/.
“Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation”. Nature Reviews. Immunology 5 (9):  688–98. (September 2005). doi:10.1038/nri1688. PMID 16138102.
“Interleukin-21: a new modulator of immunity, infection, and cancer”. Cytokine & Growth Factor Reviews 18 (3–4):  223–32. (2007). doi:10.1016/j.cytogfr.2007.04.003. PMID 17509926.
“Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation”. The Journal of Biological Chemistry 271 (17):  10334–40. (April 1996). doi:10.1074/jbc.271.17.10334. PMID 8626603.
“Cytokines: IL-21 joins the gamma(c)-dependent network?”. Current Biology 11 (5):  R175-7. (March 2001). doi:10.1016/S0960-9822(01)00087-2. PMID 11267886.
“Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex”. Journal of Immunology 167 (1):  1–5. (July 2001). doi:10.4049/jimmunol.167.1.1. PMID 11418623.
“IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response”. Journal of Immunology 169 (7):  3600–5. (October 2002). doi:10.4049/jimmunol.169.7.3600. PMID 12244150.
“Human IL-21 and IL-4 bind to partially overlapping epitopes of common gamma-chain”. Biochemical and Biophysical Research Communications 300 (2):  291–6. (January 2003). doi:10.1016/S0006-291X(02)02836-X. PMID 12504082.
“IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells”. Journal of Immunology 170 (11):  5464–9. (June 2003). doi:10.4049/jimmunol.170.11.5464. PMID 12759422.
“Interleukin-21 inhibits dendritic cell activation and maturation”. Blood 102 (12):  4090–8. (December 2003). doi:10.1182/blood-2003-03-0669. PMID 12893770.
“IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors”. European Journal of Immunology 33 (12):  3439–47. (December 2003). doi:10.1002/eji.200324533. PMID 14635054.
“Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells”. Journal of Immunology 172 (9):  5154–7. (May 2004). doi:10.4049/jimmunol.172.9.5154. PMID 15100251.
“IFN-alpha regulates IL-21 and IL-21R expression in human NK and T cells”. Journal of Leukocyte Biology 76 (2):  416–22. (August 2004). doi:10.1189/jlb.1003488. PMID 15178704.
“[Cloning and expression of human interleukin-21 cDNA in E.coli]”. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology 20 (4):  406–9. (July 2004). PMID 15207081.
“Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6”. Journal of Immunology 173 (9):  5361–71. (November 2004). doi:10.4049/jimmunol.173.9.5361. PMID 15494482.
“NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression”. Proceedings of the National Academy of Sciences of the United States of America 102 (6):  2016–21. (February 2005). Bibcode: 2005PNAS..102.2016M. doi:10.1073/pnas.0409512102. PMC 548571. PMID 15684054. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548571/.