LRP6
関連文献

“LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.”. Development 131 (8):  1663–77. (2004). doi:10.1242/dev.01117. PMID 15084453.
“Generation and analysis of 280,000 human expressed sequence tags.”. Genome Res. 6 (9):  807–28. (1997). doi:10.1101/gr.6.9.807. PMID 8889549.
“A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).”. Genomics 56 (1):  40–50. (1999). doi:10.1006/geno.1998.5685. PMID 10036184.
“LDL-receptor-related proteins in Wnt signal transduction.”. Nature 407 (6803):  530–5. (2000). Bibcode: 2000Natur.407..530T. doi:10.1038/35035117. PMID 11029007.
“LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.”. Nature 411 (6835):  321–5. (2001). Bibcode: 2001Natur.411..321M. doi:10.1038/35077108. PMID 11357136.
“Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.”. Curr. Biol. 11 (12):  951–61. (2001). doi:10.1016/S0960-9822(01)00290-1. PMID 11448771.
“Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled.”. J. Biol. Chem. 277 (8):  5977–81. (2002). doi:10.1074/jbc.M111131200. PMID 11742004.
“Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26):  16899–903. (2003). doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
“Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.”. J. Biol. Chem. 278 (39):  37024–31. (2003). doi:10.1074/jbc.M300191200. PMID 12857724.
“A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor.”. Mol. Cell. Biol. 23 (16):  5825–35. (2003). doi:10.1128/MCB.23.16.5825-5835.2003. PMC 166321. PMID 12897152. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166321/.
“The low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway.”. J. Biol. Chem. 279 (17):  17535–42. (2004). doi:10.1074/jbc.M311292200. PMID 14739301.
“LDL receptor-related protein LRP6 regulates proliferation and survival through the Wnt cascade in vascular smooth muscle cells.”. Am. J. Physiol. Heart Circ. Physiol. 287 (6):  H2376–83. (2005). doi:10.1152/ajpheart.01173.2003. PMID 15271658.
“Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.”. Genome Res. 14 (9):  1711–8. (2004). doi:10.1101/gr.2435604. PMC 515316. PMID 15342556. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515316/.
“The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B):  2121–7. (2004). doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928/.
“LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution.”. Oncogene 23 (56):  9129–35. (2005). doi:10.1038/sj.onc.1208123. PMID 15516984.
“SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor.”. J. Biol. Chem. 280 (29):  26770–5. (2005). doi:10.1074/jbc.M504308200. PMID 15908424.
“Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding.”. J. Cell Sci. 118 (Pt 22):  5305–14. (2006). doi:10.1242/jcs.02651. PMID 16263759.
“The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity.”. J. Biol. Chem. 281 (8):  4787–94. (2006). doi:10.1074/jbc.M508657200. PMID 16365045.