CHEK1
関連文献

“The complexity of p53 modulation: emerging patterns from divergent signals”. Genes & Development 12 (19):  2973–83. (October 1998). doi:10.1101/gad.12.19.2973. PMID 9765199.
“The many substrates and functions of ATM”. Nature Reviews. Molecular Cell Biology 1 (3):  179–86. (December 2000). doi:10.1038/35043058. PMID 11252893.
“Claspin, a regulator of Chk1 in DNA replication stress pathway”. DNA Repair 3 (8–9):  1033–7. (2005). doi:10.1016/j.dnarep.2004.03.001. PMID 15279790.
“Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216”. Science 277 (5331):  1501–5. (September 1997). doi:10.1126/science.277.5331.1501. PMID 9278512.
“The physical association and phosphorylation of Cdc25C protein phosphatase by Prk”. Oncogene 18 (44):  6029–36. (October 1999). doi:10.1038/sj.onc.1202983. PMID 10557092.
“Substrate specificities and identification of putative substrates of ATM kinase family members”. The Journal of Biological Chemistry 274 (53):  37538–43. (December 1999). doi:10.1074/jbc.274.53.37538. PMID 10608806.
“The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites”. Genes & Development 14 (3):  289–300. (February 2000). PMC 316358. PMID 10673501. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316358/.
“The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01”. The Journal of Biological Chemistry 275 (8):  5600–5. (February 2000). doi:10.1074/jbc.275.8.5600. PMID 10681541.
“Analysis of the candidate target genes for mutation in microsatellite instability-positive cancers of the colorectum, stomach, and endometrium”. International Journal of Oncology 16 (4):  731–7. (April 2000). doi:10.3892/ijo.16.4.731. PMID 10717241.
“The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation”. Cell 100 (6):  681–92. (March 2000). doi:10.1016/S0092-8674(00)80704-7. PMID 10761933.
“Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint”. Genes & Development 14 (12):  1448–59. (June 2000). doi:10.1101/gad.840500. PMC 316686. PMID 10859164. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316686/.
“Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase”. Nature 411 (6833):  102–7. (May 2001). doi:10.1038/35075107. PMID 11333986.
“ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1”. Molecular and Cellular Biology 21 (13):  4129–39. (July 2001). doi:10.1128/MCB.21.13.4129-4139.2001. PMC 87074. PMID 11390642. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC87074/.
“Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing”. The Journal of Cell Biology 154 (5):  913–23. (September 2001). doi:10.1083/jcb.200104099. PMC 1255922. PMID 11535615. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255922/.
“Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway”. The Journal of Biological Chemistry 276 (46):  43305–12. (November 2001). doi:10.1074/jbc.M106050200. PMID 11551930.
“UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts”. Oncogene 20 (46):  6784–93. (October 2001). doi:10.1038/sj.onc.1204883. PMID 11709713.