フォールディング
注釈と出典

[脚注の使い方]
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αヘリックスの螺旋形成
主鎖内に水素結合を有する反平行βプリーツシート
タンパク質の構造をまとめた全形態
疎水性凝集（英語版）。コンパクトなフォールディング (右側)では、疎水性アミノ酸 (黒い球体として表示) が中央に向かって凝集し、水性環境から遮蔽された状態になる。
水分子が疎水性溶質の近くでより整然となるにつれて、エントロピーは減少する。
小型真核生物の熱ショックタンパク質の例
X線結晶構造解析のステップ
折りたたまれていないポリペプチド鎖が本来の構造を取るようになるエネルギー・ファンネル(漏斗)。
Folding@homeは、ここに示すようなマルコフ状態モデルを使用して、タンパク質が初期のランダムなコイル状の状態 (左) から自然の三次元構造 (右) に凝集するときに取ることができる起こりうる形状やフォールディング経路をモデル化する。