小池佑佳
著作 > 主要論文

Sugai, A.; Kato, T.; Koyama, A.; Koike, Y.; Kasahara, S.; Konno, T.; Ishihara, T.; Onodera, O. (2018). “Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data”. Frontiers in Neuroscience 12 (28). doi:10.3389/fnins.2018.00028. PMID 29449800. https://www.frontiersin.org/articles/10.3389/fnins.2018.00028/full.
Sugai, A.; Kato, T.; Koyama, A.; Koike, Y.; Konno, T.; Ishihara, T.; Onodera, O. (2019). “Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation”. Neurobiology of Disease 130 (104534). doi:10.1016/j.nbd.2019.104534. PMID 31310801. https://www.sciencedirect.com/science/article/pii/S0969996119302025?via%3Dihub.
Koike, Y.; Jansen-West, K.; Hanna Al-Shaikh, R.; Carlomagno, Y.; Song, Y.; Dunmore, J. (2021). “Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3”. Parkinsonism & Related Disorders 89. doi:10.1016/j.parkreldis.2021.07.018. PMID 34303201. https://www.sciencedirect.com/science/article/pii/S1353802021002674?via%3Dihub.
Koike, Y.; Sugai, A.; Hara, N.; Ito, J.; Yokoseki, A.; Ishihara, T.; Yamagishi, T.; Tsuboguchi, S. et al. (2021). “Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex”. Communications Biology 4 (1107). doi:10.1038/s42003-021-02621-0. PMID 34548609. https://www.nature.com/articles/s42003-021-02621-0.
Rosa, M.; Prudencio, M.; Koike, Y.; Vatsavayai, S.; Kim, G.; Harbinski, F. (2022). “TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A”. Nature 603 (7899). doi:10.1038/s41586-022-04424-7. PMID 35197626. https://www.nature.com/articles/s41586-022-04424-7.
Akiyama, T.; Koike, Y.; Petrucelli, L.; Gitler, AD. (2022). “Cracking the cryptic code in amyotrophic lateral sclerosis and frontotemporal dementia: Towards therapeutic targets and biomarkers”. Clinical and Translational Medicine 12 (5). doi:10.1002/ctm2.818. PMID 35567447. https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ctm2.818.
Pickles, S.; Gendron, TF.; Koike, Y.; Yue, M.; Song, Y.; Kachergus, JM. (2022). “Evidence of cerebellar TDP-43 loss of function in FTLD-TDP”. Acta Neuropathol Commun. 10 (1). doi:10.1186/s40478-022-01408-6. PMID 35879741. https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-022-01408-6.
Shao, W.; Todd, T.; Wu, Y.; Jones, C.; Tong, J.; Jansen-West, K.; Daughrity, L.; Park, J. et al. (2022). “Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration”. Science 378 (6615). doi:10.1126/science.abq7860. PMID 36201573. https://www.science.org/doi/10.1126/science.abq7860?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed.
Koike, Y.; Onodera, O. (2023). “Implications of miRNAs dysregulation in amyotrophic lateral sclerosis: Challenging for clinical applications”. Frontiers in Neuroscience 17 (1131758). doi:10.3389/fnins.2023.1131758. PMID 36895420. https://www.frontiersin.org/articles/10.3389/fnins.2023.1131758/full.
Koike, Y.; Pickles, S.; Estades Ayuso, V.; Jansen-West, K.; Qi, YA.; Li, Z. (2023). “TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A”. Plos Biology 21 (2). doi:10.1371/journal.pbio.3002028. PMID 36895420. https://journals.plos.org/plosbiology/article/authors?id=10.1371/journal.pbio.3002028.
Pickles, S.; Alepuz, DZ.; Koike, Y.; Yue, M.; Tong, J.; Liu, P. (2023). “CRISPR interference to evaluate modifiers of C9ORF72-mediated toxicity in FTD”. Frontiers in Cell and Developmental Biology 11 (1251551). doi:10.3389/fcell.2023.1251551. https://www.frontiersin.org/articles/10.3389/fcell.2023.1251551/abstract.