インテグリン結合キナーゼ
関連文献

“Cell-substrate interactions and signaling through ILK”. Current Opinion in Cell Biology 12 (2):  250–6. (April 2000). doi:10.1016/S0955-0674(99)00083-6. PMID 10712922.
“The role of integrin-linked kinase (ILK) in cancer progression”. Cancer Metastasis Reviews 22 (4):  375–84. (December 2003). doi:10.1023/A:1023777013659. PMID 12884912.
“Stretching to meet needs: integrin-linked kinase and the cardiac pump”. Genes & Development 20 (17):  2327–31. (September 2006). doi:10.1101/gad.1472506. PMID 16951248.
“Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4”. Genomics 42 (1):  177–9. (May 1997). doi:10.1006/geno.1997.4719. PMID 9177792.
“Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase”. Biochimica et Biophysica Acta 1358 (3):  215–20. (October 1997). doi:10.1016/S0167-4889(97)00089-X. PMID 9366252.
“ILK (beta1-integrin-linked protein kinase): a novel immunohistochemical marker for Ewing's sarcoma and primitive neuroectodermal tumour”. Virchows Archiv 433 (2):  113–7. (August 1998). doi:10.1007/s004280050225. PMID 9737788.
“The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells”. Molecular and Cellular Biology 19 (3):  2425–34. (March 1999). doi:10.1128/mcb.19.3.2425. PMC 84035. PMID 10022929. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC84035/.
“Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase”. The Journal of Biological Chemistry 274 (52):  37385–90. (December 1999). doi:10.1074/jbc.274.52.37385. PMID 10601309.
“Cloning of an isoform of integrin-linked kinase (ILK) that is upregulated in HT-144 melanoma cells following TGF-beta1 stimulation”. Oncogene 19 (27):  3069–77. (June 2000). doi:10.1038/sj.onc.1203640. PMID 10871859.
“Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain”. The Journal of Biological Chemistry 276 (7):  4932–9. (February 2001). doi:10.1074/jbc.M007632200. PMID 11078733.
“Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase C”. The Journal of Biological Chemistry 276 (17):  14400–6. (April 2001). doi:10.1074/jbc.M011093200. PMID 11278835.
“Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions”. The Journal of Biological Chemistry 276 (26):  23499–505. (June 2001). doi:10.1074/jbc.M102163200. PMID 11304546.
“A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading”. The Journal of Cell Biology 153 (3):  585–98. (April 2001). doi:10.1083/jcb.153.3.585. PMC 2190577. PMID 11331308. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190577/.
“A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction”. The Journal of Cell Biology 153 (6):  1251–64. (June 2001). doi:10.1083/jcb.153.6.1251. PMC 2192033. PMID 11402068. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192033/.
“Regulation of Akt/PKB activation by tyrosine phosphorylation”. The Journal of Biological Chemistry 276 (34):  31858–62. (August 2001). doi:10.1074/jbc.C100271200. PMID 11445557.
A) シロイヌナズナのILKのタンパク質配列の模式図。B) ILKのリピートの立体構造予測。青がN末端側で赤がC末端側。C) 立体構造の重ね合わせ。D) ILKのアミノ酸配列。