サイクリン依存性キナーゼ1
関連文献

“Cdc25 protein phosphatases in cell proliferation”. Biochim. Biophys. Acta 1332 (2):  M53–63. (1997). doi:10.1016/S0304-419X(96)00049-2. PMID 9141461.
“Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1”. DNA Cell Biol. 23 (4):  193–205. (2004). doi:10.1089/104454904773819789. PMID 15142377. https://zenodo.org/record/1235217.
“Human immunodeficiency virus type-1 accessory protein Vpr: a causative agent of the AIDS-related insulin resistance/lipodystrophy syndrome?”. Ann. N. Y. Acad. Sci. 1024:  153–167. (2004). doi:10.1196/annals.1321.013. PMID 15265780. https://zenodo.org/record/1235880.
“Structure and function of HIV-1 auxiliary regulatory protein Vpr: novel clues to drug design”. Curr. Drug Targets Immune Endocr. Metabol. Disord. 4 (4):  265–275. (2005). doi:10.2174/1568008043339668. PMID 15578977.
“The Vpr protein from HIV-1: distinct roles along the viral life cycle”. Retrovirology 2:  11. (2006). doi:10.1186/1742-4690-2-11. PMC 554975. PMID 15725353. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554975/.
“Viral infections and cell cycle G2/M regulation”. Cell Res. 15 (3):  143–149. (2005). doi:10.1038/sj.cr.7290279. PMID 15780175.
“HIV-1 viral protein R (Vpr) & host cellular responses”. Indian J. Med. Res. 121 (4):  270–86. (2005). PMID 15817944.
“Cell cycle sibling rivalry: Cdc2 vs. Cdk2”. Cell Cycle 4 (11):  1491–1494. (2007). doi:10.4161/cc.4.11.2124. PMID 16258277.
“Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions”. Cell Res. 15 (11–12):  923–934. (2006). doi:10.1038/sj.cr.7290370. PMID 16354571.
“[Biologic availability and "1st pass" effect of drugs]”. Fortschr. Med. 95 (28):  1765–6, 1774–80. (1977). PMID 914146.
“Interaction between the cell-cycle-control proteins p34cdc2 and p9CKShs2. Evidence for two cooperative binding domains in p9CKShs2”. Eur. J. Biochem. 203 (3):  353–360. (1992). doi:10.1111/j.1432-1033.1992.tb16557.x. PMID 1310466.
“cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication”. EMBO J. 11 (6):  2189–99. (1992). doi:10.1002/j.1460-2075.1992.tb05278.x. PMC 556686. PMID 1318195. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC556686/.
“Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle”. Science 257 (5077):  1689–1694. (1992). doi:10.1126/science.1388288. PMID 1388288.
“Casein kinase II phosphorylates p34cdc2 kinase in G1 phase of the HeLa cell division cycle”. J. Biol. Chem. 267 (28):  20317–25. (1992). PMID 1400350.
“Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis”. Mol. Cell. Biol. 12 (10):  4634–42. (1992). doi:10.1128/MCB.12.10.4634. PMC 360390. PMID 1406653. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC360390/.
“Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle”. EMBO J. 11 (12):  4379–89. (1992). doi:10.1002/j.1460-2075.1992.tb05538.x. PMC 557012. PMID 1425574. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC557012/.
“A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression”. J. Biol. Chem. 266 (35):  23521–4. (1992). PMID 1748630.
“The retinoblastoma protein is phosphorylated on multiple sites by human cdc2”. EMBO J. 10 (13):  4279–90. (1992). doi:10.1002/j.1460-2075.1991.tb05006.x. PMC 453181. PMID 1756735. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC453181/.
“Regional assignment of the human cell cycle control gene CDC2 to chromosome 10q21 by in situ hybridization”. Hum. Genet. 87 (5):  621–2. (1991). doi:10.1007/BF00209025. PMID 1916766.
“Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein”. J. Biol. Chem. 266 (30):  19945–52. (1991). PMID 1939057.
S. cerevisiaeの細胞周期の進行におけるCdk1（Cdc28）の役割を示した模式図。Cln3-Cdk1はCln1,2-Cdk1の活性化を引き起こし、 その後Clb5,6-Cdk1、Clb1-4-Cdk1の活性化を引き起こす。