プロテアーゼ活性化受容体1
関連文献

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トロンビンによるPAR1の切断の概要。トロンビン（赤）はPAR1の細胞外N末端の切断部位に結合する。トロンビンはArg41とSer42の間のペプチド結合を切断し、テザードリガンドとなる新たなN末端が形成され、切断ペプチド（橙）は細胞外へ放出される。
アンタゴニスト、ボラパキサルが結合したPAR1の構造。7回膜貫通ヘリックスがシアン、細胞外ループが緑、細胞内ループが橙、がボラパキサルが赤で示されている。C末端テールは描かれていない。