Daftar Perdana Menteri Guinea-Bissau
List of officeholders

African Party for the Independence of Guinea and Cape Verde (PAIGC)
Party for Social Renewal (PRS)
Assembly of the People United (APU)
Independent
Denotes Acting Prime Minister
| N | Portrait | Name (Birth–Death) | Election | Term of office> Took office | Term of office> Left office | Political party |
| --- | --- | --- | --- | --- | --- | --- |
| 1 |  | Francisco Mendes (1939–1978) | 1976–77 | 24 September 1973 | 7 July 1978 (died in office) | PAIGC |
| 2 |  | Umaru Djaló (–) |  | 7 July 1978 | 7 July 1978 | PAIGC |
| 3 |  | Constantino Teixeira (?–1988) | — | 7 July 1978 | 28 September 1978 | PAIGC |
| 4 |  | João Bernardo Vieira (1939–2009) | — | 28 September 1978 | 14 November 1980 | PAIGC |
| 5 |  | Victor Saúde Maria (1939–1999) | — | 14 November 1980 | 10 March 1984 | PAIGC |
| 6 |  | Paulo Correia (1942–1986) |  | May 1984 | 7 November 1985 | PAIGC |
| 7 |  | Iafai Camará (–) |  | 7 November 1985 | April 1987 | PAIGC |
| 8 |  | Manuel dos Santos 'Manecas' (born 1942 |  | April 1987 | June 1989 | PAIGC |
| 9 |  | Vasco Cabral (1926–2005) |  | 21 June 1989 | 27 December 1991 | PAIGC |
| 10 |  | Carlos Correia (1933–2021) | 1994 | 27 December 1991 | 26 October 1994 | PAIGC |
| 11 |  | Manuel Saturnino da Costa (1942–2021) | — | 26 October 1994 | 6 June 1997 | PAIGC |
| 10 |  | Carlos Correia (1933–2021) | — | 6 June 1997 | 3 December 1998 | PAIGC |
| 11 |  | Francisco Fadul (born 1953) | 1999 | 3 December 1998 | 19 February 2000 | Independent |
| 12 |  | Caetano N'Tchama (1955–2007) | — | 19 February 2000 | 19 March 2001 | PRS |
| 13 |  | Faustino Imbali (born 1956) | — | 21 March 2001 | 9 December 2001 | Independent |
| 14 |  | Alamara Nhassé (born 1957) | — | 9 December 2001 | 17 November 2002 | PRS |
| 15 |  | Mário Pires (born 1949) | — | 17 November 2002 | 14 September 2003  | PRS |
| 16 |  | Kumba Ialá (1953–2014) | 1999–2000 | 13 September 2003 | 14 September 2003 (deposed) | PRS |
| 17 |  | General Veríssimo Correia Seabra (1947–2004) Chairman of the Military Committee for the Restoration of Constitutional and Democratic Order | — | 14 September 2003 | 28 September 2003 | Military |
| 18 |  | Henrique Rosa (1946–2013) Acting | — | 28 September 2003 | 28 September 2003 | Independent |
| 19 |  | Artur Sanhá (born 1965) | — | 28 September 2003 | 10 May 2004 | PRS |
| 20 |  | Carlos Gomes Júnior (born 1949) | 2004 | 10 May 2004 | 2 November 2005 | PAIGC |
| 21 |  | Aristides Gomes (born 1954) | — | 2 November 2005 | 13 April 2007 | PAIGC |
| 22 |  | Martinho Ndafa Kabi (born 1957) | — | 13 April 2007 | 5 August 2008 | PAIGC |
| 10 |  | Carlos Correia (1933–2021) | — | 5 August 2008 | 2 January 2009 | PAIGC |
| 20 |  | Carlos Gomes Júnior (born 1949) | 2008 | 2 January 2009 | 10 February 2012 | PAIGC |
| 23 |  | Adiato Djaló Nandigna (born 1958) | — | 10 February 2012 | 12 April 2012 (deposed) | PAIGC |
| 24 |  | Raimundo Pereira (born 1955) Acting | — | 12 April 2012 | 12 April 2012 (deposed) | PAIGC |
| 25 |  | Major general Mamadu Ture Kuruma (born 1947) Chairman of the Military Command | — | 12 April 2012 | 11 May 2012 | Military |
| 26 |  | Manuel Serifo Nhamadjo (1958–2020) | — | 11 May 2012 | 16 May 2012 | Independent |
| 27 |  | Rui Duarte de Barros (born 1960)  | — | 16 May 2012 | 3 July 2014 | Independent |
| 28 |  | Domingos Simões Pereira (born 1964) | 2014 | 3 July 2014 | 20 August 2015 | PAIGC |
| 29 |  | Baciro Djá (born 1973) | — | 20 August 2015 | 17 September 2015 | PAIGC |
| 10 |  | Carlos Correia (1933–2021) | — | 17 September 2015 | 27 May 2016 | PAIGC |
| 29 |  | Baciro Djá (born 1973) | — | 27 May 2016 | 18 November 2016 | PAIGC |
| 30 |  | Umaro Sissoco Embaló (born 1972) | — | 18 November 2016 | 30 January 2018 | PAIGC |
| 31 |  | Artur Silva (born 1956?) | — | 30 January 2018 | 16 April 2018 | PAIGC |
| 21 |  | Aristides Gomes (born 1954) | 2019 | 16 April 2018 | 29 October 2019 | PAIGC |
| 11 |  | Faustino Imbali (born 1956) | — | 31 October 2019 | 8 November 2019 | Independent |
| 21 |  | Aristides Gomes (born 1954) | — | 8 November 2019 | 28 February 2020 | PAIGC |
| 32 |  | Nuno Gomes Nabiam (born 1966) | — | 28 February 2020 | 8 August 2023 | APU |
| 33 |  | Geraldo Martins (born 1967) | 2023 | 8 August 2023 | 21 December 2023 | PAIGC |
| 27 |  | Rui Duarte de Barros (born 1960) | — | 21 December 2023 | Incumbent | Independent |