Penampilan Terbaik oleh seorang Pemeran Perempuan dalam sebuah Peran Pendukung (Screen Actors Guild Award)
Pemenang dan nominasi > 2000-an

| Tahun | Aktris | Film | Peran | Ref>  |
| --- | --- | --- | --- | --- |
| 2000 (ke-7) | Judi Dench | Chocolat | Armande Voizin |  |
| 2000 (ke-7) | Kate Hudson | Almost Famous | Penny Lane |  |
| 2000 (ke-7) | Frances McDormand | Almost Famous | Elaine Miller |  |
| 2000 (ke-7) | Julie Walters | Billy Elliot | Mrs. Wilkinson |  |
| 2000 (ke-7) | Kate Winslet | Quills | Madeleine "Maddy" LeClerc |  |
| 2001 (ke-8) | Helen Mirren | Gosford Park | Mrs. Wilson |  |
| 2001 (ke-8) | Cate Blanchett | Bandits | Kate Wheeler |  |
| 2001 (ke-8) | Judi Dench | The Shipping News | Agnis Hamm |  |
| 2001 (ke-8) | Cameron Diaz | Vanilla Sky | Julianna "Julie" Gianni |  |
| 2001 (ke-8) | Dakota Fanning | I Am Sam | Lucy Dawson |  |
| 2002 (ke-9) | Catherine Zeta-Jones  | Chicago | Velma Kelly |  |
| 2002 (ke-9) | Kathy Bates | About Schmidt | Roberta Hertzel |  |
| 2002 (ke-9) | Queen Latifah | Chicago | Matron "Mama" Morton" |  |
| 2002 (ke-9) | Julianne Moore | The Hours | Laura Brown |  |
| 2002 (ke-9) | Michelle Pfeiffer | White Oleander | Ingrid Magnussen |  |
| 2003 (ke-10) | Renée Zellweger  | Cold Mountain | Ruby Thewes |  |
| 2003 (ke-10) | Maria Bello | The Cooler | Natalie Belisario |  |
| 2003 (ke-10) | Keisha Castle-Hughes | Whale Rider | Paike Apirana |  |
| 2003 (ke-10) | Patricia Clarkson | Pieces of April | Joy Burns |  |
| 2003 (ke-10) | Holly Hunter | Thirteen | Melanie Freeland |  |
| 2004 (ke-11) | Cate Blanchett  | The Aviator | Katharine Hepburn |  |
| 2004 (ke-11) | Cloris Leachman | Spanglish | Evelyn Wright |  |
| 2004 (ke-11) | Laura Linney | Kinsey | Clara McMillen |  |
| 2004 (ke-11) | Virginia Madsen | Sideways | Maya Randall |  |
| 2004 (ke-11) | Sophie Okonedo | Hotel Rwanda | Tatiana Rusesabagina |  |
| 2005 (ke-12) | Rachel Weisz  | The Constant Gardener | Tessa Quayle |  |
| 2005 (ke-12) | Amy Adams | Junebug | Ashley Johnsten |  |
| 2005 (ke-12) | Catherine Keener | Capote | Nelle Harper Lee |  |
| 2005 (ke-12) | Frances McDormand | North Country | Glory Dodge |  |
| 2005 (ke-12) | Michelle Williams | Brokeback Mountain | Alma Beers Del Mar |  |
| 2006 (ke-13) | Jennifer Hudson  | Dreamgirls | Effie White |  |
| 2006 (ke-13) | Adriana Barraza | Babel | Amelia Hernández |  |
| 2006 (ke-13) | Cate Blanchett | Notes on a Scandal | Sheba Hart |  |
| 2006 (ke-13) | Abigail Breslin | Little Miss Sunshine | Olive Hoover |  |
| 2006 (ke-13) | Rinko Kikuchi | Babel | Chieko Wataya |  |
| 2007 (ke-14) | Ruby Dee | American Gangster | Mahalee Lucas |  |
| 2007 (ke-14) | Cate Blanchett | I'm Not There | Jude Quinn |  |
| 2007 (ke-14) | Catherine Keener | Into the Wild | Jan Burres |  |
| 2007 (ke-14) | Amy Ryan | Gone Baby Gone | Helene McCready |  |
| 2007 (ke-14) | Tilda Swinton  | Michael Clayton | Karen Crowder |  |
| 2008 (ke-15) | Kate Winslet   won Academy Award for Best Actress | The Reader | Hanna Schmitz |  |
| 2008 (ke-15) | Amy Adams | Doubt | Sister James |  |
| 2008 (ke-15) | Penélope Cruz  | Vicky Cristina Barcelona | María Elena |  |
| 2008 (ke-15) | Viola Davis | Doubt | Mrs. Miller |  |
| 2008 (ke-15) | Taraji P. Henson | The Curious Case of Benjamin Button | Queenie Jackson |  |
| 2009 (ke-16) | Mo'Nique  | Precious | Mary Lee Johnston |  |
| 2009 (ke-16) | Penélope Cruz | Nine | Carla Albanese |  |
| 2009 (ke-16) | Vera Farmiga | Up in the Air | Alex Goran |  |
| 2009 (ke-16) | Anna Kendrick | Up in the Air | Natalie Keener |  |
| 2009 (ke-16) | Diane Kruger | Inglourious Basterds | Bridget von Hammersmark |  |