גני HOX
הערות שוליים

↑  Homeboxes, National Library of Medicine, ‏3 ביולי 2020
↑  Peter W. H. Holland., Evolution of homeobox genes, Wiley Interdisciplinary Reviews-Developmental Biology, 2012, עמ' 31-45
1 2  Bürglin TR., Affolter M., Homeodomain proteins: an update, Chromosoma 125, 2016, עמ' 497–521
↑  המושג Homeo מקורו מהמילה היוונית hómoios - ומשמעותו, במסגרת מחקר הבסיס המולקולרי של ההתפתחות העוברית, יצירת מבנה מסוים במקום מסוים (סגמנט) בגוף העובר.
↑  Bürglin TR., Homeodomain Subtypes and Functional Diversity, Sub-cellular biochemistry 52, 2011, עמ' 95-122
↑  Young RA, Control of the embryonic stem cell state, Cell 144, 2011, עמ' 940- 954
1 2  S. Samuel, H. Naora, Homeobox gene expression in cancer: Insights fromdevelopmental regulation and deregulation, European Journal of Cancer 41, 2005, עמ' 2428–2437
↑  Driever W, Nüsslein-Volhard C, The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner, Cell 54, 1988, עמ' 95-104
↑  Brandt R, Cabedo M, Xie Y, Wenkel S, Homeodomain leucine-zipper proteins and their role in synchronizing growth and development with the environment, J Integr Plant Biol 56, 2014, עמ' 518-526
↑  Costanzo E, Trehin C, Vandenbussche M, The role of WOX genes in flower development, Ann Bot 114, 2014, עמ' 1545-1553
↑  Tsuda K, Hake S, Diverse functions of KNOX transcription factors in the diploid body plan of plants, Curr Opin Plant Biol 27, 2015, עמ' 91-96
↑  J. Taipale and P.A. Beachy, The Hedgehog and Wnt signalling pathways in cancer, Nature 411, 2001, עמ' 349-354
↑  T. Reya and H. Clevers, Wnt signalling in stem cells and cancer, Nature 434, 2005, עמ' 843-850
↑  G. Hu, H. Lee, S.M. Price, Msx homeobox genes inhibit differentiation through upregulation of cyclin D1, Development 128, 2001, עמ' 2373-2384
↑  Bateson, W, Materrals for the Study of Variation, London: MacMillan and Co, 1894
↑  Lewis,E.B, Genes and developmental pathways, Am. Zool. 3, 1963, עמ' 33-56
↑  Lewis,E.B, A gene complex controlling segmentation in Drosophila, Nature 276, 1978, עמ' 565-570
↑  Duncan,I. and Lewis,E.B, Developmental Order: Its Origin and Regulation, NY: A.R.Liss, 1982, עמ' 533-554
↑  Lewis,R.A., Kaufman,T.C., Denell,R.E. and Tallerico,P, Lewis,R.A., Kaufman,T.C., Denell,R.E. and Tallerico,P, , Genetics 95, 1980, Genetics 95, 1980, עמ' 367-381
↑  Kaufman,T.C., Lewis,R. and Wakimoto,B., Cytogenetic Analysis of Chromosome 3 in DROSOPHILA MELANOGASTER: The Homoeotic Gene Complex in Polytene Chromosome Interval 84a-B, Genetics 94, 1980, עמ' 115-133
↑  Lewis,E.B, Drosophila Inf, Inf. Serv, 1956, עמ' 76
↑  Falk,R, Drosophila Inf, Serv, 1964, עמ' 60
↑  McGinnis W, Levine MS, Hafen E, Kuroiwa A, Gehring WJ, A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes, Nature 308, 1984b, עמ' 428-433
↑  Carrasco AE, McGinnis W, Gehring WJ, De Robertis EM, Cloning of an X. laevis gene expressed during early embryogenesis coding for a peptide region homologous to Drosophila homeotic genes, Cell 37, 1984, עמ' 409-414
1 2 3 4  W. J. Gehring, M. Affolter, T. Bürglin, Homeodomain proteins, Annual Review of Biochemistry 63, 1994, עמ' 487-526
↑  H. Mihara, E.T. Kaiser, A chemically synthesized Antennapedia homeo domain binds to a specific DNA sequence, Science 242, 1988, עמ' 925-927
↑  C. O. Pabo, R. T. Sauer, Transcription Factors: Structural Families and Principles of DNA Recognition, Annual Review of Biochemistry 61, 1992, עמ' 1053-1095
↑  W. J. Gehring, Y. Q. Qian, M. Billeter, K. Furukubo-Tokunaga, A. F.Schier, D. Resendez-Perez, M. Affolter, G. Otting, K. Wüthrich, Homeodomain-DNA recognition, Cell 78, 1994, עמ' 211-223
↑  Zhong Y-F, Butts T, Holland PWH, HomeoDB: adatabase of homeobox gene diversity, Evol Dev 10, 2008, עמ' 516–518
↑  Zhong Y-F, Holland PWH, HomeoDB2: functional expansion of a comparative homeobox gene databasefor evolutionary developmental biology, Evol Dev 13, 2011, עמ' 567–568
↑  Bharathan G, Janssen BJ, Kellogg EA, Sinha N, Did homeodomain proteins duplicate before the origin of angiosperms, fungi, and metazoa?, Proceedings of the National Academy of Sciences of the United States of America 94, 1997, עמ' 49-53
↑  Frank H. Ruddle, Janet L. Bartels, Kevin L. Bentley, Claudia Kappen1, Michael T. Murtha , and John W. Pendleton, Evolution of HOX genes, Annu. Rev. Genet 28, 1994, עמ' 23-42
↑  Garcia-Fernàndez J, The genesis and evolution of homeobox gene clusters, Nature Reviews Genetics 6, 2005, עמ' 81-92
↑  Duboule D, Morata G, Colinearity and functional hierarchy among genes of the homeotic complexes, Trends Genet 10, 1994, עמ' 358–364
↑  Crow KD, Stadler PF, Lynch VJ, Amemiya C, Wagner GP, The “fish-specific” Hox cluster duplication is coincident with the origin of teleosts, Mol Biol Evol 23, 2006, עמ' 121-136
↑  Kaufman, T. C., Seeger, M. A. & Olsen, G, Molecular and genetic organization of the antennapedia gene complex of Drosophila melanogaster, Adv. Genet 27, 1990, עמ' 309-362
↑  Hunter CP, Kenyon C, Specification of anteroposterior cell fates in Caenorhabditis elegans by Drosophila Hox proteins, Nature 377, 1995, עמ' 229-32
↑  Damen WGM, Tautz D, A Hox class 3 orthologue from the spider Cupiennius salei is expressed in a Hox-gene-like fashion, Dev Genes 208, 1998, עמ' 586-590
↑  Stauber M, Jäckle H, Schmidt-Ott U, The anterior determinant bicoid of Drosophila is a derived Hox class 3 gene, Proc Natl Acad Sci USA 96, 1999, עמ' 3786–3789
↑  Stauber M, Prell A, Schmidt-Ott U, A single Hox3 gene with composite bicoid and zerknüllt expression characteristics in non-Cyclorrhaphan flies, . Proc Natl Acad Sci USA 99, 2002, עמ' 274-279
↑  Krumlauf, R, Hox genes in vertebrate development, Cell 78, 1994, עמ' 191-201
↑  Brooke, N.M., Garcia-Fernandez, J., Holland, P.W.H., The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster, Nature 392, 1998, עמ' 920-922
↑  Dawes R, Dawson I, Falciani F, Tear G, Akam M, Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression, Development 120, 1994, עמ' 1561-1572
↑  Ferrier DE, Minguillon C, Evolution of the Hox/ParaHox gene clusters, Int J Dev Biol 47, 2003, עמ' 605-611
↑  Brooke NM, Garcia-Fernàndez J, Holland PWH, The ParaHox gene cluster is an evolutionary sister of the Hox gene cluster, Nature 392, 1998, עמ' 920-922
↑  Garcia-Fernàndez J, The genesis and evolution of homeobox gene clusters, Nat Rev Genet 6, 2005, עמ' 811-892
↑  Herr W, Sturm RA, Clerc RG, Corcoran LM, Baltimore D, Sharp PA, Ingraham HA, Rosenfeld MG, Finney M, Ruvkun G, et al, The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products, Genes Dev 2, 1988, עמ' 1513-1516
↑  R. Josephson, T. Müller, J. Pickel, S. Okabe, K. Reynolds, P. A. Turner, A. Zimmer and R. D. G. McKay, POU transcription factors control expression of CNS stem cell-specific genes, Development 125, 1998, עמ' 3087-3100
↑  P. WH Holland, H. Anne F Booth, E. A. Bruford, Classification and nomenclature of all human homeobox genes, BMC Biol. 5, 2007, עמ' 47
↑  Kagoshima H, Cassata G, Bürglin TR, A Caenorhabditis elegans homeobox gene expressed in the male tail, a link between pattern formation and sexual dimophism?, Dev Genes Evol 209, 1999, עמ' 59-62
↑  Mukherjee K, Brocchieri L, Bürglin TR, A comprehensive classification and evolutionary analysis of plant homeobox genes, Mol Biol Evol 26, 2009, עמ' 2775-2794
↑  R. W. Williams, Plant homeobox genes: many functions stem from a common motif, Bioessays, 1998, עמ' 280-2
איור 1: תיאור מפת הגן (AntP) ‏ Antennapedia ומיקום ה-homeodomain. פאנל תחתון: רצף חומצות האמינו באזור ה-homeodomain של הגן.
גני HOX בזבוב הדרוזופילה (פאנל עליון) ובאדם (פאנלים תחתונים – HOXA-D). סדר הגנים בגנום הוא לפי סדר האיברים בגוף.