JUNQ ו-IPOD
הערות שוליים

↑  Treusch, Sebastian; Cyr, Douglas M.; Lindquist, Susan (2009). "Amyloid deposits: Protection against toxic protein species?". Cell Cycle. 8 (11): 1668–74. doi:10.4161/cc.8.11.8503. PMID 19411847.
1 2 3  Tyedmers, Jens; Mogk, Axel; Bukau, Bernd (2010). "Cellular strategies for controlling protein aggregation". Nature Reviews Molecular Cell Biology. 11 (11): 777–88. doi:10.1038/nrm2993. PMID 20944667.
1 2 3 4 5  Kaganovich, Daniel; Kopito, Ron; Frydman, Judith (2008). "Misfolded proteins partition between two distinct quality control compartments". Nature. 454 (7208): 1088–95. Bibcode:2008Natur.454.1088K. doi:10.1038/nature07195. PMC 2746971. PMID 18756251.
1 2  Specht, S.; Miller, S. B. M.; Mogk, A.; Bukau, B. (2011). "Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiae". The Journal of Cell Biology. 195 (4): 617–29. doi:10.1083/jcb.201106037. PMC 3257523. PMID 22065637.
↑  Nystrom, T. (2010). "Spatial protein quality control and the evolution of lineage-specific ageing". Philosophical Transactions of the Royal Society B: Biological Sciences. 366 (1561): 71–5. doi:10.1098/rstb.2010.0282. PMC 3001311. PMID 21115532.
↑  Morimoto, R. I.; Cuervo, A. M. (2009). "Protein Homeostasis and Aging: Taking Care of Proteins from the Cradle to the Grave". The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 64A (2): 167–70. doi:10.1093/gerona/gln071. PMC 2655025. PMID 19228787.
1 2  Powers, Evan T.; Morimoto, Richard I.; Dillin, Andrew; Kelly, Jeffery W.; Balch, William E. (2009). "Biological and Chemical Approaches to Diseases of Proteostasis Deficiency". Annual Review of Biochemistry. 78: 959–91. doi:10.1146/annurev.biochem.052308.114844. PMID 19298183.
1 2  Ben-Zvi, A.; Miller, E. A.; Morimoto, R. I. (2009). "Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging". Proceedings of the National Academy of Sciences. 106 (35): 14914–9. Bibcode:2009PNAS..10614914B. doi:10.1073/pnas.0902882106. JSTOR 40484529. PMC 2736453. PMID 19706382.
↑  http://www.microscopyu.com/articles/livecellimaging/פרק זה לוקה בחסר. אנא תרמו לוויקיפדיה ו. ייתכן שתמצאו פירוט בדף השיחה.
1 2  Lippincott-Schwartz, J.; Patterson, GH (2003). "Development and Use of Fluorescent Protein Markers in Living Cells". Science. 300 (5616): 87–91. Bibcode:2003Sci...300...87L. doi:10.1126/science.1082520. PMID 12677058.
↑  Seufert, W.; Seufert, W (1996). "A Yeast Ubc9 Mutant Protein with Temperature-sensitive in Vivo Function is Subject to Conditional Proteolysis by a Ubiquitin- and Proteasome-dependent Pathway". Journal of Biological Chemistry. 271 (42): 25790–6. doi:10.1074/jbc.271.42.25790. PMID 8824207.
↑  Tongaonkar, Prasad; Beck, Konrad; Shinde, Ujwal P.; Madura, Kiran (1999). "Characterization of a Temperature-Sensitive Mutant of a Ubiquitin-Conjugating Enzyme and Its Use as a Heat-Inducible Degradation Signal". Analytical Biochemistry. 272 (2): 263–9. doi:10.1006/abio.1999.4190. PMID 10415098.
↑  England, Jeremy L.; Kaganovich, Daniel (2011). "Polyglutamine shows a urea-like affinity for unfolded cytosolic protein". FEBS Letters. 585 (2): 381–4. doi:10.1016/j.febslet.2010.12.023. PMID 21176779.
↑  Tyedmers, J.; Treusch, S.; Dong, J.; McCaffery, J. M.; Bevis, B.; Lindquist, S. (2010). "Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation". Proceedings of the National Academy of Sciences. 107 (19): 8633–8. Bibcode:2010PNAS..107.8633T. doi:10.1073/pnas.1003895107. PMC 2889312. PMID 20421488.
תאים אאוקריוטים ממיינים חלבונים שאבדו את המבנה התקין שלהם לשני מדורי בקרת איכות תוך תאיים: 1. JUNQ (ירוק), הקשור לגרעין (כתום)

2.IPOD (ירוק), הקשור לחלולית (צל שחור)
צבר חלבוני VHL הנמצא ב-JUNQ (ירוק), אשר קשור לגרעין (כתום)
צבר IPOD (אדום), שקשור לחלולית (ירוק)