מיגל וייל
מאמרים נבחרים

L.J. Solmesky, M .Shuman, M .Goldsmith, M. Weil*, and D. Peer*. Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: A high content analysis approach. Nanotechnology, Vol. 22 (49), 2011 (pp. 494016).
H. Nachmany, S. Wald, M. Abekasis, S. Bulvik, M. Weil*. Two Potential Biomarkers identified in Mesenchymal stem cells and Leukocytes of patients with sporadic amyotrophic lateral sclerosis. Disease Markers, Vol. 32, 2012 (pp. 211-220).
E. Lilo, S. Wald-Altman, L.J. Solmesky, K. Ben Yaakov, N. Gershoni-Emek, S. Bulvik, I. Kassis, D. Karussis, E. Perlson, M. Weil*. Characterization of human sporadic ALS biomarkers in the familial ALS transgenic mSOD1G93A mouse model. Hum Mol Genet, Vol. 22(23), 2013 (pp. 4720-4725).
L. J. Solmesky, M. Weil*. Personalized drug discovery: HCA approach optimized for rare diseases at Tel Aviv University. Comb Chem High Throughput Screen, Vol. 17(3), 2014 (pp. 253-255).
A. Abashidze, V. Gold, Y. Anavi, H. Greenspan, M. Weil*. Involvement of IKAP in peripheral target innervation and in specific JNK and NGF signals in developing PNS neurons. Plos One, Vol 9(11), 2014 (pp. e113428).
S. Lefler, MA. Cohen, G. Kantor, D. Cheishvili, A. Even, A. Birger, T. Turetsky, Y. Gil, S. Even-Ram, E. Aizenman, N. Bashir. C. Maayan, A. Razin, BE. Reubinoff, M. Weil*. Familial Dysautonomia (FD) human embryonic stem cell derived PNS neurons reveal that synaptic vesicular and neuronal transport genes are directly or indirectly affected by IKBKAP downregulation. Plos One, Vol 10(10), 2014 (pp. e0138807).
S. Wald-Altman, E. Pichinuk, O. Kakhlon, M. Weil*. A differential autophagy dependent response to DNA-double strand breaks in bone marrow mesenchymal stem cells from sporadic ALS patients. Disease Models and Mechanisms, Vol 10(5), 2017 (pp. 645-654).
LJ. Solmesky, N. Khazanov, H. Senderowitz, P. Wang, BA. Minassian, IM. Ferreira, WW. Yue, A. Lossos, M. Weil*, O. Kakhlon*. A novel image-based high throughput screening assay discovers therapeutic candidates for adult polyglucosan body disease. Biochem J., Vol 474(20), 2017 (pp. 3403-3420).
G. Morelli, A. Even, I. Gladwyn-Ng, R. Le Bail, M. Shilian, JD. Godin, E. Peyre, BA. Hassan, A. Besson, J-M. Rigo, M. Weil, B. Brône, L. Nguyen*. p27Kip1 modulates axonal transport by regulating α tubulin acetyltransferase 1 stability. Cell Reports, Vol 23(8), 2018 (pp.2429-2442).
R. Maimon, A. Ionescu, A. Bonnie, S. Sweetat, S. Wald-Altman, S. Inbar, T. Gradus, D. Trotti, M. Weil, O. Behar, E. Perlson*. miR126-5p down-regulation facilitates axon degeneration and NMJ disruption via a non-cell-autonomous mechanism in ALS. The Journal of Neuroscience, Vol 38 (24), 2018 (pp.5478-5494).
O. Kakhlon*, I. Ferreira, L.J. Solmesky, N. Khazanov, A. Lossos, R. Alvarez, D. Yetil, S. Pampou, M. Weil, H. Senderowitz, P. Escriba, W. W. Yue, H. Orhan Akman. Guaiacol as a drug-candidate for testing Adult Polyglucosan Body Disease. JCI Insight., Vol 3(17), 2018 (pii: 99694
W. Massalha, M. Markovits, E. Pichinuk, Y. Feinstein-Rotkopf, M. Tarshish, K. Mishra, V. Llado, M. Weil, PV. Escriba, O. Kakhlon*. Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity. Biosci Rep., Vol 39(1), 2019 (pii: BSR20181661).
A. Even^, G. Morelli^, C. Scaramuzzino, I. Gladwyn-Ng, R. Le Bail, M. Shilian, B. Franco, V. Holdengreber, S. Freeman, M. M. Magiera, A.S. Jijumon, B. Malgrange, B. Brone, P. Dietrich, I. Dragatsis, C. Janke, F. Saudou, M. Weil*^, L. Nguyen*^. ATAT1-enriched vesicles promote microtubule acetylation via axonal transport. Science Advances., Vol 5 (12), 2019 eaax2705. A. Even^, G. Morelli^, S. Turchetto ^, M. Shilian, R. Le Bail, S. Laguesse, N. Krusy, A. Brisker, A. Brandis, S. Inbar, A. Chariot, F. Saudou, P. Dietrich, I. Dragatsis, B. Brone, L. Broix, J-M. Rigo, M. Weil*^, L. Nguyen *^. ATP-Citrate lyase promotes axonal transport across species. Nat. Comm., 12(1), 2021 5878. Online publication https://doi.org/10.1038/s41467-021-25786-y.
O. Kakhlon*, H. Vaknin^, K. Mishra^, J. D’Souza^, M. Marisat, U. Sprecher, S. Wald-Altman, A. Dukhovny, Y. Raviv, B. Da’adoosh, H. Engel, S. Benhamron, K. Nitzan, S. Sweetat, A. Permyakova, A. Mordechai, H. O. Akman, H. Rosenmann, A. Lossos, J. Tam, B. A. Minassian, M. Weil*. Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism. EMBO Mol. Med., 2021 e14554.