Parhaan naispääosan SAG-palkinto
Voittajat ja ehdokkaat > 2000-vuosikymmen

| Vuosi | Näyttelijä | Elokuva | Rooli |
| --- | --- | --- | --- |
| 2000 | Julia Roberts | Erin Brockovich | Erin Brockovich † |
| 2000 | Joan Allen | Kandidaatti | Laine Billings Hanson ‡ |
| 2000 | Juliette Binoche | Pieni suklaapuoti | Vianne Rocher ‡ |
| 2000 | Ellen Burstyn | Unelmien sielunmessu | Sara Goldfarb ‡ |
| 2000 | Laura Linney | You Can Count on Me | Samantha "Sammy" Prescott ‡ |
| 2001 | Halle Berry | Monster’s Ball | Leticia Musgrove † |
| 2001 | Jennifer Connelly | Kaunis mieli | Alicia Nash† |
| 2001 | Judi Dench | Iris | Iris Murdoch ‡ |
| 2001 | Sissy Spacek | Satimessa | Ruth Fowler ‡ |
| 2001 | Renée Zellweger | Bridget Jones – elämäni sinkkuna | Bridget Jones ‡ |
| 2002 | Renée Zellweger | Chicago | Roxie Hart ‡ |
| 2002 | Salma Hayek | Frida | Frida Kahlo ‡ |
| 2002 | Nicole Kidman | Tunnit | Virginia Woolf † |
| 2002 | Diane Lane | Kohtalokas syrjähyppy | Connie Sumner ‡ |
| 2002 | Julianne Moore | Kaukana taivaasta | Cathy Whitaker ‡ |
| 2003 | Charlize Theron | Monster – Aileen Wuornos | Aileen Wuornos † |
| 2003 | Patricia Clarkson | The Station Agent | Olivia Harris |
| 2003 | Diane Keaton | Jotain annettavaa | Erica Barry ‡ |
| 2003 | Naomi Watts | 21 grammaa | Cristina Peck ‡ |
| 2003 | Evan Rachel Wood | Kolmetoista | Tracy Louise Freeland |
| 2004 | Hilary Swank | Million Dollar Baby | Maggie Fitzgerald † |
| 2004 | Annette Bening | Being Julia | Julia Lambert ‡ |
| 2004 | Catalina Sandino Moreno | Maria Full of Grace | María Álvarez ‡ |
| 2004 | Imelda Staunton | Vera Drake | Vera Drake ‡ |
| 2004 | Kate Winslet | Tahraton mieli | Clementine Kruczynski ‡ |
| 2005 | Reese Witherspoon | Walk the Line | June Carter † |
| 2005 | Judi Dench | Mrs. Henderson esittää | Laura Henderson ‡ |
| 2005 | Felicity Huffman | Transamerica | Stanley Schupak/Sabrina "Bree" Osbourne ‡ |
| 2005 | Charlize Theron | North Country | Josey Aimes ‡ |
| 2005 | Ziyi Zhang | Geishan muistelmat | Chiyo Sakamoto/Sayuri Nitta |
| 2006 | Helen Mirren | The Queen | kuningatar Elisabet II † |
| 2006 | Penélope Cruz | Volver – paluu | Raimunda ‡ |
| 2006 | Judi Dench | Paljastavat merkinnät | Barbara Covett ‡ |
| 2006 | Meryl Streep | Paholainen pukeutuu Pradaan | Miranda Priestly ‡ |
| 2006 | Kate Winslet | Little Children | Sarah Pierce ‡ |
| 2007 | Julie Christie | Away from Her | Fiona Anderson ‡ |
| 2007 | Cate Blanchett | Elisabet – kultainen aikakausi | Elisabet I ‡ |
| 2007 | Marion Cotillard | Pariisin varpunen – Edith Piaf | Edith Piaf † |
| 2007 | Angelina Jolie | A Mighty Heart – taipumaton | Mariane Pearl |
| 2007 | Ellen Page | Juno | Juno MacGuff ‡ |
| 2008 | Meryl Streep | Doubt – Epäilys | Aloysius Beauvier ‡ |
| 2008 | Anne Hathaway | Rachel Getting Married | Kym ‡ |
| 2008 | Angelina Jolie | Changeling – vaihdokas | Christine Collins ‡ |
| 2008 | Melissa Leo | Frozen River | Ray Eddy ‡ |
| 2008 | Kate Winslet | Revolutionary Road | April Wheeler |
| 2009 | Sandra Bullock | Elämä pelissä | Leigh Anne Tuohy † |
| 2009 | Helen Mirren | Viimeinen asema | Sophia Tolstaya ‡ |
| 2009 | Carey Mulligan | An Education | Jenny Miller ‡ |
| 2009 | Gabourey Sidibe | Precious | Claireece "Precious" Jones ‡ |
| 2009 | Meryl Streep | Julie & Julia | Julia Child ‡ |