HK1
بیشتر بخوانید

Daniele A, Altruda F, Ferrone M, Silengo L, Romeo G, Archidiacono N, Rocchi M (1992). "Mapping of human hexokinase 1 gene to 10q11----qter". Human Heredity. 42 (2): 107–10. doi:10.1159/000154049. PMID 1572668.
Magnani M, Bianchi M, Casabianca A, Stocchi V, Daniele A, Altruda F, Ferrone M, Silengo L (Jul 1992). "A recombinant human 'mini'-hexokinase is catalytically active and regulated by hexose 6-phosphates". The Biochemical Journal. 285 (1): 193–9. doi:10.1042/bj2850193. PMC 1132765. PMID 1637300.
Magnani M, Serafini G, Bianchi M, Casabianca A, Stocchi V (Jan 1991). "Human hexokinase type I microheterogeneity is due to different amino-terminal sequences". The Journal of Biological Chemistry. 266 (1): 502–5. PMID 1985912.
Adams V, Griffin LD, Gelb BD, McCabe ER (Jun 1991). "Protein kinase activity of rat brain hexokinase". Biochemical and Biophysical Research Communications. 177 (3): 1101–6. doi:10.1016/0006-291X(91)90652-N. PMID 2059200.
Murakami K, Blei F, Tilton W, Seaman C, Piomelli S (Feb 1990). "An isozyme of hexokinase specific for the human red blood cell (HKR)". Blood. 75 (3): 770–5. PMID 2297576.
Nishi S, Seino S, Bell GI (Dec 1988). "Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous". Biochemical and Biophysical Research Communications. 157 (3): 937–43. doi:10.1016/S0006-291X(88)80964-1. PMID 3207429.
Rijksen G, Akkerman JW, van den Wall Bake AW, Hofstede DP, Staal GE (Jan 1983). "Generalized hexokinase deficiency in the blood cells of a patient with nonspherocytic hemolytic anemia". Blood. 61 (1): 12–8. PMID 6848140.
Bianchi M, Magnani M (1995). "Hexokinase mutations that produce nonspherocytic hemolytic anemia". Blood Cells, Molecules & Diseases. 21 (1): 2–8. doi:10.1006/bcmd.1995.0002. PMID 7655856.
Blachly-Dyson E, Zambronicz EB, Yu WH, Adams V, McCabe ER, Adelman J, Colombini M, Forte M (Jan 1993). "Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel". The Journal of Biological Chemistry. 268 (3): 1835–41. PMID 8420959.
Aleshin AE, Zeng C, Fromm HJ, Honzatko RB (Aug 1996). "Crystallization and preliminary X-ray analysis of human brain hexokinase". FEBS Letters. 391 (1–2): 9–10. doi:10.1016/0014-5793(96)00688-6. PMID 8706938.
Visconti PE, Olds-Clarke P, Moss SB, Kalab P, Travis AJ, de las Heras M, Kopf GS (Jan 1996). "Properties and localization of a tyrosine phosphorylated form of hexokinase in mouse sperm". Molecular Reproduction and Development. 43 (1): 82–93. doi:10.1002/(SICI)1098-2795(199601)43:1<82::AID-MRD11>3.0.CO;2-6. PMID 8720117.
Mori C, Nakamura N, Welch JE, Shiota K, Eddy EM (May 1996). "Testis-specific expression of mRNAs for a unique human type 1 hexokinase lacking the porin-binding domain". Molecular Reproduction and Development. 44 (1): 14–22. doi:10.1002/(SICI)1098-2795(199605)44:1<14::AID-MRD2>3.0.CO;2-W. PMID 8722688.
Murakami K, Piomelli S (Feb 1997). "Identification of the cDNA for human red blood cell-specific hexokinase isozyme". Blood. 89 (3): 762–6. PMID 9028305.
Ruzzo A, Andreoni F, Magnani M (Jan 1998). "An erythroid-specific exon is present in the human hexokinase gene". Blood. 91 (1): 363–4. PMID 9414310.
Travis AJ, Foster JA, Rosenbaum NA, Visconti PE, Gerton GL, Kopf GS, Moss SB (Feb 1998). "Targeting of a germ cell-specific type 1 hexokinase lacking a porin-binding domain to the mitochondria as well as to the head and fibrous sheath of murine spermatozoa". Molecular Biology of the Cell. 9 (2): 263–76. doi:10.1091/mbc.9.2.263. PMC 25249. PMID 9450953.
Aleshin AE, Zeng C, Bourenkov GP, Bartunik HD, Fromm HJ, Honzatko RB (Jan 1998). "The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate". Structure. 6 (1): 39–50. doi:10.1016/S0969-2126(98)00006-9. PMID 9493266.
Ruzzo A, Andreoni F, Magnani M (Apr 1998). "Structure of the human hexokinase type I gene and nucleotide sequence of the 5' flanking region". The Biochemical Journal. 331 (2): 607–13. doi:10.1042/bj3310607. PMC 1219395. PMID 9531504.
Aleshin AE, Zeng C, Bartunik HD, Fromm HJ, Honzatko RB (Sep 1998). "Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate". Journal of Molecular Biology. 282 (2): 345–57. doi:10.1006/jmbi.1998.2017. PMID 9735292.
Murakami K, Kanno H, Miwa S, Piomelli S (Jun 1999). "Human HKR isozyme: organization of the hexokinase I gene, the erythroid-specific promoter, and transcription initiation site". Molecular Genetics and Metabolism. 67 (2): 118–30. doi:10.1006/mgme.1999.2842. PMID 10356311.
| ن ب ونگارخانه PDB | ن ب ونگارخانه PDB |
| --- | --- |
 1bg3: RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE  1cza: MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE, GLUCOSE-6-PHOSPHATE, AND ADP  1dgk: MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE  1hkb: CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE  1hkc: RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND PHOSPHATE  1qha: HUMAN HEXOKINASE TYPE I COMPLEXED WITH ATP ANALOGUE AMP-PNP :  1bg3: RAT BRAIN HEXOKINASE TYPE I COMPLEX WITH GLUCOSE AND INHIBITOR GLUCOSE-6-PHOSPHATE  1cza: MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE, GLUCOSE-6-PHOSPHATE, AND ADP  1dgk: MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE  1hkb: CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE  1hkc: RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND PHOSPHATE  1qha: HUMAN HEXOKINASE TYPE I COMPLEXED WITH ATP ANALOGUE AMP-PNP