E2F4
قراءة متعمقة

Bandyopadhyay D، Timchenko N، Suwa T، وآخرون (2001). "The human melanocyte: a model system to study the complexity of cellular aging and transformation in non-fibroblastic cells". Exp. Gerontol. ج. 36 ع. 8: 1265–75. DOI:10.1016/S0531-5565(01)00098-5. PMID:11602203.
Beijersbergen RL، Kerkhoven RM، Zhu L، وآخرون (1994). "E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo". Genes Dev. ج. 8 ع. 22: 2680–90. DOI:10.1101/gad.8.22.2680. PMID:7958925.
Xiao ZX، Ginsberg D، Ewen M، Livingston DM (1996). "Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 10: 4633–7. DOI:10.1073/pnas.93.10.4633. PMC:39330. PMID:8643455.
Moberg K، Starz MA، Lees JA (1996). "E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry". Mol. Cell. Biol. ج. 16 ع. 4: 1436–49. PMC:231128. PMID:8657117.
Vidal M، Brachmann RK، Fattaey A، وآخرون (1996). "Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 19: 10315–20. DOI:10.1073/pnas.93.19.10315. PMC:38381. PMID:8816797.
Williams CD، Linch DC، Sørensen TS، وآخرون (1997). "The predominant E2F complex in human primary haemopoietic cells and in AML blasts contains E2F-4, DP-1 and p130". Br. J. Haematol. ج. 96 ع. 4: 688–96. DOI:10.1046/j.1365-2141.1997.d01-2086.x. PMID:9074408.
Lindeman GJ، Gaubatz S، Livingston DM، Ginsberg D (1997). "The subcellular localization of E2F-4 is cell-cycle dependent". Proc. Natl. Acad. Sci. U.S.A. ج. 94 ع. 10: 5095–100. DOI:10.1073/pnas.94.10.5095. PMC:24637. PMID:9144196.
Wang H، Shao N، Ding QM، وآخرون (1997). "BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases". Oncogene. ج. 15 ع. 2: 143–57. DOI:10.1038/sj.onc.1201252. PMID:9244350.
Müller H، Moroni MC، Vigo E، وآخرون (1997). "Induction of S-phase entry by E2F transcription factors depends on their nuclear localization". Mol. Cell. Biol. ج. 17 ع. 9: 5508–20. PMC:232399. PMID:9271426.
Pierce AM، Schneider-Broussard R، Philhower JL، Johnson DG (1998). "Differential activities of E2F family members: unique functions in regulating transcription". Mol. Carcinog. ج. 22 ع. 3: 190–8. DOI:10.1002/(SICI)1098-2744(199807)22:3<190::AID-MC7>3.0.CO;2-P. PMID:9688145.
Ferreira R، Magnaghi-Jaulin L، Robin P، وآخرون (1998). "The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase". Proc. Natl. Acad. Sci. U.S.A. ج. 95 ع. 18: 10493–8. DOI:10.1073/pnas.95.18.10493. PMC:27922. PMID:9724731.
Timchenko NA، Wilde M، Darlington GJ (1999). "C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice". Mol. Cell. Biol. ج. 19 ع. 4: 2936–45. PMC:84088. PMID:10082561.
Zheng N، Fraenkel E، Pabo CO، Pavletich NP (1999). "Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP". Genes Dev. ج. 13 ع. 6: 666–74. DOI:10.1101/gad.13.6.666. PMC:316551. PMID:10090723.
Furukawa Y، Iwase S، Kikuchi J، وآخرون (1999). "Transcriptional repression of the E2F-1 gene by interferon-alpha is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes". Oncogene. ج. 18 ع. 11: 2003–14. DOI:10.1038/sj.onc.1202500. PMID:10208422.
Lam EW، Glassford J، van der Sman J، وآخرون (1999). "Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors". Eur. J. Immunol. ج. 29 ع. 10: 3380–9. DOI:10.1002/(SICI)1521-4141(199910)29:10<3380::AID-IMMU3380>3.0.CO;2-C. PMID:10540350.
Zhong X، Hemmi H، Koike J، وآخرون (2000). "Various AGC repeat numbers in the coding region of the human transcription factor gene E2F-4". Hum. Mutat. ج. 15 ع. 3: 296–7. DOI:10.1002/(SICI)1098-1004(200003)15:3<296::AID-HUMU18>3.0.CO;2-X. PMID:10679953.
Takahashi Y، Rayman JB، Dynlacht BD (2000). "Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression". Genes Dev. ج. 14 ع. 7: 804–16. DOI:10.1101/gad.14.7.804. PMC:316494. PMID:10766737.
Schwemmle S، Pfeifer GP (2000). "Genomic structure and mutation screening of the E2F4 gene in human tumors". Int. J. Cancer. ج. 86 ع. 5: 672–7. DOI:10.1002/(SICI)1097-0215(20000601)86:5<672::AID-IJC11>3.0.CO;2-X. PMID:10797289.
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معرفات كيميائية:  قاعدة بيانات التتابع المرجعي (RefSeq RNA): NM_001950  
| ع ن جينات الكروموسوم 16 | ع ن جينات الكروموسوم 16 |
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جينات الكروموسوم 16:  RAB26  ARL6IP1  CLDN6  PARD6A  C16orf62  ZNF23  MT1X  TSC2  FBXO31  KIFC3  SRRM2  TBX6  MYLPF  EXOC3L  SEPT12  ENKD1  RSL1D1  TERF2IP  CDH15  VAC14  CBFA2T3  ELMO3  Periplakin  CMTM2  MT1B  PRRT2  C16orf58  UQCRC2  MKL2  ZFPM1  CNOT1  ABCC12  IRX6  MT1E  TNP2  LOC124220  SHCBP1  CCL22  CDH11  ATXN2L  NPW  KATNB1  WFDC1  NUPR1  KIAA0182  PDPR  IGFALS  TBC1D24  CHTF18  BAIAP3  RBFOX1  BBS2  NFATC2IP  FHOD1  DDX19B  SLC7A5  E2F4  ZNF423  MLST8  GLG1  METRN  PRSS8  CENPN  XPO6  RPGRIP1L  CDH8  ZNF469  WFIKKN1  PRKCB1  TOX3  VPS35  E4F1  IRX3  RBBP6  FOXF1  EFCBP2  NDE1  COG7  GNAO1  TRAP1  HERPUD1  ZP2  CDYL2  ARHGDIG  ZNF267  ABAT  NOB1  COTL1  KIAA0430  CD2BP2  TANGO6  TBL3  KCTD13  RHBDF1  KIAA0174  TMEM219  PMFBP1  COQ9  KIF22  EIF3C  SEPT1  DNAJA2  GABARAPL2  CIRH1A  NIP7  FA2H  DOK4  PDIA2  CNTNAP4  CLDN9  IRX5  RGS11  GNG13  CMTM3  ATBF1  RAB11FIP3  FBRS  HBQ1  SOX8  ORC6  SNTB2  CRYM  ERAF  TNRC6A  COG4  FAM57B  GFER  NIP30  DYNC1LI2  WDR24  CFDP1  MRPL28  GINS2  NME4  GTF3C1  LRRC50  NDRG4  DCTN5  DOC2A  CTRB2  SF3B3  CCP110  VAT1L  SETD6  GLIS2  RRAD  PRR35  MT1F  Metallothionein-3  LUC7L  CBFB  TELO2  ARMC5  VPS4A  TUFM  ZNF598  STX1B  HSF4  CIITA  PAM16  NPRL3  HN1L  C16orf7  HIRIP3  PLEKHG4  AKTIP  ZNF19  LITAF  PYCARD  JPH3  KDM8  EMP2  TFAP4  TXNL4B  CENPT  NFATC3 
بوابة الكيمياء الحيوية
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي
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التصنيفات الطبية:  دليل الوراثة المندلية عند البشر (OMIM): 600659  
المعرفات الخارجية:  Ensembl Transcript ID: ENST00000568839  نظام اللغة الطبية الموحدة (UMLS CUI): C1414227