EGLN2
قراءة متعمقة

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Jaakkola P، Mole DR، Tian YM، وآخرون (2001). "Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation". Science. ج. 292 ع. 5516: 468–72. DOI:10.1126/science.1059796. PMID:11292861.
Ivan M، Kondo K، Yang H، وآخرون (2001). "HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing". Science. ج. 292 ع. 5516: 464–8. DOI:10.1126/science.1059817. PMID:11292862.
Taylor MS (2001). "Characterization and comparative analysis of the EGLN gene family". Gene. ج. 275 ع. 1: 125–32. DOI:10.1016/S0378-1119(01)00633-3. PMID:11574160.
Epstein AC، Gleadle JM، McNeill LA، وآخرون (2001). "C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation". Cell. ج. 107 ع. 1: 43–54. DOI:10.1016/S0092-8674(01)00507-4. PMID:11595184.
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Min JH، Yang H، Ivan M، وآخرون (2002). "Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling". Science. ج. 296 ع. 5574: 1886–9. DOI:10.1126/science.1073440. PMID:12004076.
McNeill LA، Hewitson KS، Gleadle JM، وآخرون (2002). "The use of dioxygen by HIF prolyl hydroxylase (PHD1)". Bioorg. Med. Chem. Lett. ج. 12 ع. 12: 1547–50. DOI:10.1016/S0960-894X(02)00219-6. PMID:12039559.
Oehme F، Ellinghaus P، Kolkhof P، وآخرون (2002). "Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors". Biochem. Biophys. Res. Commun. ج. 296 ع. 2: 343–9. DOI:10.1016/S0006-291X(02)00862-8. PMID:12163023.
Ivan M، Haberberger T، Gervasi DC، وآخرون (2002). "Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 21: 13459–64. DOI:10.1073/pnas.192342099. PMC:129695. PMID:12351678.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Metzen E، Berchner-Pfannschmidt U، Stengel P، وآخرون (2003). "Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing". J. Cell Sci. ج. 116 ع. Pt 7: 1319–26. DOI:10.1242/jcs.00318. PMID:12615973.
Cioffi CL، Liu XQ، Kosinski PA، وآخرون (2003). "Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells". Biochem. Biophys. Res. Commun. ج. 303 ع. 3: 947–53. DOI:10.1016/S0006-291X(03)00453-4. PMID:12670503.
Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Aprelikova O، Chandramouli GV، Wood M، وآخرون (2004). "Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors". J. Cell. Biochem. ج. 92 ع. 3: 491–501. DOI:10.1002/jcb.20067. PMID:15156561.
Colland F، Jacq X، Trouplin V، وآخرون (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
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معرفات كيميائية:  قاعدة بيانات التتابع المرجعي (RefSeq RNA): NM_053046  
| ع ن جينات الكروموسوم 19 | ع ن جينات الكروموسوم 19 |
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