register space */
} pmu_reg_addr_mgmt_addr;

/* Internal functions */
static u32 pmu_reg_read(platform_pmu_t *pmu, u32 relative_address);
static void pmu_reg_write(platform_pmu_t *pmu, u32 relative_address, u32 new_val);
static mali_pmm_core_mask pmu_translate_cores_to_pmu(mali_pmm_core_mask cores);
#if PMU_TEST
static void pmm_pmu_dump_regs( platform_pmu_t *pmu );
static pmm_pmu_test( platform_pmu_t *pmu, u32 cores );
#endif

_mali_osk_errcode_t mali_pmm_pmu_init(_mali_osk_resource_t *resource)
{

	if( resource->type == PMU )
	{
		if( (resource->base == 0) ||
			(resource->description == NULL) )
		{
			/* NOTE: We currently don't care about any other resource settings */
			MALI_PRINT_ERROR(("PLATFORM mali400-pmu: Missing PMU set up information\n"));
			MALI_ERROR(_MALI_OSK_ERR_INVALID_ARGS);
		}
		pmu_info = (platform_pmu_t *)_mali_osk_malloc(sizeof(*pmu_info));
		MALI_CHECK_NON_NULL( pmu_info, _MALI_OSK_ERR_NOMEM );

		/* All values get 0 as default */
		_mali_osk_memset(pmu_info, 0, sizeof(*pmu_info));

		pmu_info->reg_base_addr = resource->base;
		pmu_info->reg_size = (u32)PMU_REGISTER_ADDRESS_SPACE_SIZE;
		pmu_info->name = resource->description;
		pmu_info->irq_num = resource->irq;

		if( _MALI_OSK_ERR_OK != _mali_osk_mem_reqregion(pmu_info->reg_base_addr, pmu_info->reg_size, pmu_info->name) )
		{
			MALI_PRINT_ERROR(("PLATFORM mali400-pmu: Could not request register region (0x%08X - 0x%08X) for %s\n",
					 pmu_info->reg_base_addr, pmu_info->reg_base_addr + pmu_info->reg_size - 1, pmu_info->name));
			goto cleanup;
		}
		else
		{
			MALI_DEBUG_PRINT( 4, ("PLATFORM mali400-pmu: Success: request_mem_region: (0x%08X - 0x%08X) for %s\n",
					 pmu_info->reg_base_addr, pmu_info->reg_base_addr + pmu_info->reg_size -  return dnnAllocateBuffer_F64(pPtr, layout);
}

template <typename Dtype> inline dnnError_t dnnReleaseBuffer(
    void *ptr);
template <> inline dnnError_t dnnReleaseBuffer<float>(
    void *ptr) {
    return dnnReleaseBuffer_F32(ptr);
}
template <> inline dnnError_t dnnReleaseBuffer<double>(
    void *ptr) {
    return dnnReleaseBuffer_F64(ptr);
}

template <typename Dtype> inline dnnError_t dnnLayoutDelete(
    dnnLayout_t layout);
template <> inline dnnError_t dnnLayoutDelete<float>(
    dnnLayout_t layout) {
    return dnnLayoutDelete_F32(layout);
}
template <> inline dnnError_t dnnLayoutDelete<double>(
    dnnLayout_t layout) {
    return dnnLayoutDelete_F64(layout);
}

template <typename Dtype> inline dnnError_t dnnPrimitiveAttributesCreate(
    dnnPrimitiveAttributes_t *attributes);
template <> inline dnnError_t dnnPrimitiveAttributesCreate<float>(
    dnnPrimitiveAttributes_t *attributes) {
    return dnnPrimitiveAttributesCreate_F32(attributes);
}
template <> inline dnnError_t dnnPrimitiveAttributesCreate<double>(
    dnnPrimitiveAttributes_t *attributes) {
    return dnnPrimitiveAttributesCreate_F64(attributes);
}

template <typename Dtype> inline


return dnnConversionExecute_F64(conversion, from, to);
}

template <typename Dtype> inline dnnError_t dnnConvolutionCreateForward(
    dnnPrimitive_t* pConvolution,
    dnnPrimitiveAttributes_t attributes,
    dnnAlgorithm_t algorithm,
    size_t dimension, const size_t srcSize[], const size_t dstSize[], const size_t filterSize[],
    const size_t convolutionStrides[], const int inputOffset[], const dnnBorder_t border_type);
template <> inline dnnError_t dnnConvolutionCreateForward<float>(
    dnnPrimitive_t* pConvolution,
    dnnPrimitiveAttributes_t attributes,
    dnnAlgorithm_t algorithm,
    size_t dimension, const size_t srcSize[], const size_t dstSize[], const size_t filterSize[],
    const size_t convolutionStrides[], const int inputOffset[], const dnnBorder_t border_type) {
    return dnnConvolutionCreateForward_F32(
               pConvolution,
            convolutionStrides[], const int inputOffset[], const dnnBorder_t border_type) {
    return dnnConvolutionCreateBackwardFilter_F64(
               pConvolution,
               attributes,
               algorithm,
               dimension, srcSize, dstSize, filterSize,
               convolutionStrides, inputOffset, border_type);
}

template <typename Dtype> inline dnnError_t dnnConvolutionCreateBackwardBias(
    dnnPrimitive_t* pConvolution,
    dnnPrimitiveAttributes_t attributes,
    dnnAlgorithm_t algorithm,
    size_t dimension, const size_t dstSize[]);
template <> inline dnnError_t dnnConvolutionCreateBackwardBias<float>(


<typename Dtype> inline dnnError_t dnnSplitCreate(
    dnnPrimitive_t *pSplit,
    dnnPrimitiveAttributes_t attributes,
    const size_t N,
    dnnLayout_t src,
    size_t dst[]);
template <> inline dnnError_t dnnSplitCreate<float>(
    dnnPrimitive_t *pSplit,
    dnnPrimitiveAttributes_t attributes,
    const size_t N,
    dnnLayout_t src,
    size_t dst[]) {
    return dnnSplitCreate_F32(
               pSplit,
               attributes,
               N,
               src,
 be like 20 years old or something.”

Following his set, the comic walked over to see if we were fine. We were. We really were. It was over and we went home. I fell asleep on the car ride back. (It was 9:15, after all.)

A few days later I remembered the incident and asked my husband if he thought it was anti-Semitic. We both agreed that it didn’t bother us. We had lived in New York and understood there are differences between Jewish communities that must be obvious to outside groups: Anecdotally, Jews outside of New York are less likely to be engaged in real estate. Visibly Jewish people in Ohio are generally less politically active and many have less accumulated wealth than Jews in New York.

Comedians use stereotypes


especially cringe-worthy.

But I understand what he meant. I grew up Orthodox and outside of New York. I knew from a young age that we Pittsburgh Jews were not like New York Jews. The religious Jews in New York were super Jewish. They were intense about a dozen things I’d never heard of — which kinds of kosher foods were not kosher enough and the exact measurements of long skirts, for example. Many of them had never met a Jewish family unlike their own. They couldn’t imagine the encounters I had while walking on the street, and I could never understand why they were always running somewhere.

Then I moved to New York and so much became clear. The lifestyle is expensive, the needs are great and the opportunities canthe virus can be mutated or passed reoccurring between individuals."

"They have not given them masks, or cleaning supplies that would be beneficial regarding his recovery," Bradford noted, citing the jail's lack of preparedness. "This is against all recommendations of the Surgeon General and CDC."

The 20-year-old rapper's legal team is asking the judge to allow Melly to be released and placed on house arrest so that he can be treated at a medical facility at his own expense.

Over the weekend, it was announced that Melly had "tested positive for COVID-19 today while awaiting his trial in Broward County Jail."

"He’ll be filing a motion for restricted release in hopes of better care due to any jails not being prepared to treat this new virus," read the statement shared on Instagram.


the least common multiple of 2 and (-12)/8 - (3 + (-222)/12).
14
Calculate the lowest common multiple of 1294 and (21/(-35))/((-3)/30).
3882
What is the common denominator of 4 + (-1266)/252 + (-1)/(-2) and -55/12?
84
Suppose -23*i = -21*i - 24. Let k be 5/(-10)*2*0. Suppose i = 3*u, -u = -5*n - k*n + 31. What is the least common multiple of n and 8?
56
Let d = 145121/6894 - 379/18. Let s = 155680466 + -298128102358/1915. Let a = s - d. Calculate the common denominator of 33/8 and a.
40
Let x = 55 - 5. Suppose x = -8*v + 3*v. Let a = v + 23. Calculate the lowest common multiple of 5 and a.
65
Suppose -41*t + 2024 = 51*t. Calculate the smallest common multiple of t and 3512.
38632
Let m1 + 1. Suppose 3*l - 2*c = 72, -i*l + p = -l - 4*c. Calculate the lowest common multiple of 12 and l.
132
What is the common denominator of (-2 - 31/(-8))/((-3)/(-30)) and -45/44?
44
What is the common denominator of ((-3)/(36/15))/((-44)/(-8)) and -21/376?
4136
Let f(d) = d**2 + 7*d - 34. Calculate the smallest common multiple of 14 and f(-11).
70
Find the common denominator of -26/5 and (616/13440)/(4/18).
160
Let y(i) = -i**3 + 10*i**2 + 8*i + 25. Let t be y(11). Calculate the lowest common multiple of 4 and 6*t/(-12)*4.
16
Let w = 43916/9 + -4885. What is the common denominator of w and -125/36?
36
Suppose -14730 = 5*l - 4030. Let u = 19328/9 + l. Find the common denominator of 14/51 and u.
153
What is the lowest common multiple of 24


2013

This sprawling, six-lane box is actually two in one, with northbound and southbound vehicles following long dotted-line arches as they enter and exit the interstate. "It is such a huge intersection, you would expect it to have a high crash rate." says Sioux Falls Principal Traffic Engineer Heath Hoftiezer. What city and state transportation officials are trying to determine is whether the volume of crashes — 39 in the last 26 months — is higher than it should be for an intersection of its size. "Possibly not, but we will look at what's going on with the intersection," Hoftiezer said.

9. West 41st Street and South Minnesota

39 crashes, 6 injuries, 1 fatality since Jan. 2013

City traffic engineers have known for years that traffic signals at this intersection were difficultAdvancing drug discovery through systems biology.
Pharmaceutical companies are facing an urgent need to both increase their lead compound and clinical candidate portfolios and satisfy market demands for continued innovation and revenue growth. Here, we outline an emerging approach that attempts to facilitate and alleviate many of the current drug discovery issues and problems. This is, in part, achieved through the systematic integration of technologies, which results in a superior output of data and information, thereby enhancing our understanding of biological function, chemico-biological interactions and, ultimately, drug discovery. Systems biology is one new discipline that is positioned to significantly impact this process.


Two British nationals have been arrested on the holiday island of Madeira on suspicion of smuggling £2 million pounds worth of cocaine aboard a luxury cruise liner.

The pair, were amongst 12 people, who were detained when the cruise ship, the MSC Opera, docked at Funchal en route from the Caribbean on March 24.

Local police assisted by members of Britain's National Crime Agency (NCA) recovered around 18 kilograms of cocaine, with an estimated street value of £2 million.

The cocaine had been hidden in crisp packets and ceramic bowls which had been stashed in suitcases.

Six of those arrested had been passengers on board the vessel when it travelled from the West Indies to Madeira.

The other six, including the two Britons, and a Dutch national who lives in London, had recentlywere obtained from ATCC (Manassas, VA). PANC-1 cells were maintained in Dulbecco\'s modified Eagle\'s medium containing penicillin (50 U ml^-1^), streptomycin (50 U ml^-1^) and 10% fetal bovine serum (FBS). MIA PaCa-2 cells were maintained in Dulbecco\'s modified Eagle\'s medium containing penicillin (50 U ml^-1^), streptomycin (50 U ml^-1^), 10% FBS and 2.5% horse serum (HS). Media came from ATCC. Supplements, FBS and HS were obtained from Gibco BRL (Grand Island, NY). DMSO was purchased from Sigma (St. Louis, MO). All other chemicals and reagents were of analytical grade. Anti-cleaved PARP antibody was obtained from BD Biosciences (San Jose, CA and anti-β-actin antibody was obtained from Santa Cruz Biotechnology (Santa Cruz, CA). Anti-CHOP, anti-phospho-eIF2α and anti-eIF2α antibodies were obtained from Cell Signaling Technology (Beverly, MA). Anti-Hsp70 was obtained


separately in liquid nitrogen.

Apoptosis measurement in tumor xenograft {#sec008}
----------------------------------------

All formalin-fixed tumors were embedded in paraffin within 48 h and five-micrometer sections were stained with hematoxylin and eosin (H&E). The slides were viewed under a Leica microscope (Leica Instruments, Melville, NY) and apoptosis in the viable tumor cell area was quantified by counting apoptotic bodies in four 20 x fields of view for n = 6--12 tumors per group by 2 independent observers.

Toxicology studies *in vivo* {#sec009}
----------------------------

Toxicity of PA was evaluated in the 6 weeks old female nude mice (Harlan, Indianapolis, IN). The mice were acclimatized for 1 week and treated with PA (0, 25 or 50 mg kg^-1^ of body weight, n = 15 per group) by i.p. 3 times per week for additional 5 weeks. The bodyfor the individual t-tests. Apoptosis was confirmed in C) PANC-1 and D) MIA PaCa-2 cells treated with same concentrations of PA for 24 h. Representative blots show expression of PARP cleavage (c-PARP) and β-actin was used as loading control. Three independent experiments were done for the western blot studies and quantitative data composed of all the experiments in E) PANC-1 and F) MIA PaCa-2 cells with statistical analysis were shown below the representative blot image. \*P\<0.050 was considered to be significant when compared to control (n = 3) by Student t-test. The graphical data represent mean +/- SD.](pone.0122270.g001){#pone.0122270.g001}

Apoptosis inducing effects of PA were further confirmed by increased expression of cleaved PARP (c-PARP). PARP is a 116-kDa nuclear poly (ADP-ribose) polymerase, which is involved in DNA repair in response


PA further supports development of PA in the treatment of pancreatic cancer.

Gene expression profiling by microarray has been widely used in screening drug targets \[[@pone.0122270.ref048]\]. In order to investigate the effect of PA and its possible mechanisms of action with regard to gemcitabine-resistant pancreatic cancer, we treated MIA PaCa-2 cells with PA and the expression of genes was monitored using array technology. Many cancer-related genes were significantly up and down-regulated upon PA treatment. Here, we report for the first time that the mechanisms modulating PA effect may be mediated through triggering a prolonged ER stress response in chemotherapy resistant pancreatic cancer cells, which leads to apoptosis.

[Fig 9](#pone.0122270.g009){ref-type="fig"} depicts a model for the involvement of ER in PA-induced apoptosis in chemotherapy resistant pancreatic cancer cells. The expression of HSRuseful to distinguish between prompt (E$_\gamma=1274$keV) and annihilation quanta (E$_\gamma\leq511$keV).

Selection of data
=================

Three data-taking campaigns are already concluded with the experiment for commissioning and physics studies which is equivalent to approx. 700 h of data taking with different configuration and settings of detection system.[^2] Apart of threshold synchronization and calibration measurements the data were collected also for performance studies according to NEMA standards which were so far evaluated based on the simulations only [@KowalskiActa2015; @KowalskiActa2016]. Measurements were performed also with XAD-4 polymer target and 6 different polymer samples. Data is acquired in the triggerless mode therefore an offline reconstruction and signal selection is required for background rejection [@jpetJINST; @jpetDAQ; @jpetFrame]. For o-Ps data sample main background contribution is detector based scattering when 2 annihilation gamma quanta from p-Ps are registered together with


Set of dead nodes
  uint                  _dead_node_count;       // Number of dead nodes; VectorSet::Size() is O(N).
                                                // So use this to keep count and make the call O(1).
  DEBUG_ONLY( Unique_Node_List* _modified_nodes; )  // List of nodes which inputs were modified

  debug_only(static int _debug_idx;)            // Monotonic      // Results of parse-time PhaseGVN
  Unique_Node_List*     _for_igvn;              // Initial work-list for next round of Iterative GVN
  WarmCallInfo*         _warm_calls;            // Sorted work-list for heat-based inlining.

  GrowableArray<CallGenerator*> _late_inlines;        // List of CallGenerators to be revisited after


char* msg = NULL) {
    stringStream ss;
    CompileTask::print_inlining_inner(&ss, method, inline_level, bci, msg);
    print_inlining_stream()->print("%s", ss.as_string());
  }

#ifndef PRODUCT
  IdealGraphPrinter* printer() { return _printer; }
#endif

  void log_late_inline(CallGenerator* cg);
  void log_inline_id(CallGenerator* cg);
  void log_inline_failure(const char* msg);

  void* replay_inline_data() const { return _replay_inline_data; }

  // Dump inlining replay data to the stream.
  void dump_inline_data(outputStream* out);

 private:
  // Matching, CFG layout, allocation, code generation
  PhaseCFG*             _cfg;                   // Results of CFG finding
  bool            Useful for setting breakpoints in the debugger.
  int               compile_id() const          { return _compile_id; }
  DirectiveSet*     directive() const           { return _directive; }

  // Does this compilation allow instructions to subsume loads?  User
  // instructions that subsume a load may result in an unschedulable
  // instruction sequence.
  bool              subsume_loads() const       { return _subsume_loads; }
  /** Do escape analysis. */
  bool


      _trap_hist[r] = c; }
  uint              trap_count(uint r) const    { assert(r < trapHistLength, "oob"); return _trap_hist[r]; }
  bool              trap_can_recompile() const  { return _trap_can_recompile; }
  void          set_trap_can_recompile(bool z)  { _trap_can_recompile = z; }
  uint              decompile_count() const     { return _decompile_count; }
  void          set_decompile_count(uint c)     { _decompile_count = c; }
 &igvn);
  bool is_predicate_opaq(Node * n) {
    return _predicate_opaqs->contains(n);
  }

  // Are there candidate expensive nodes for optimization?
  bool should_optimize_expensive_nodes(PhaseIterGVN &igvn);
  // Check whether n1 and n2 are similar
  static int cmp_expensive_nodes(Node* n1, Node* n2);
  // Sort expensive nodes to locate similar expensive nodes
  void sort_expensive_nodes();

  // Compilation environment.
  Arena*      comp_arena()           { return &_comp_arena; }
  ciEnv*      env() const            { return _env; }
  CompileLog* log() const            { return _log; }
  bool


               int idx, bool can_grow = false);

  void grow_node_notes(GrowableArray<Node_Notes*>* arr, int grow_by);

  // Type management
  Arena*            type_arena()                { return _type_arena; }
  Dict*             type_dict()                 { return _type_dict; }
  void*             type_hwm()                         get_alias_index(const TypePtr* at)  { return alias_type(at)->index(); }
  const TypePtr*    get_adr_type(uint aidx)             { return alias_type(aidx)->adr_type(); }
  int               get_general_index(uint aidx)        { return alias_type(aidx)->general_index(); }

  // Building nodes
  void              rethrow_exceptions(JVMState* jvms);
  void              return_values(JVMState* jvms);
  JVMState*         build_start_state(StartNode* start, const TypeFunc* tf);

  // Decide


 bool          starts_bundle(const Node *n) const;
  bool          need_stack_bang(int frame_size_in_bytes) const;
  bool          need_register_stack_bang() const;

  void  update_interpreter_frame_size(int size) {
    if (_interpreter_frame_size < size) {
      _interpreter_frame_size = size;
    }
  }
  int           bang_size_in_bytes() const;

  void          set_matcher(Matcher* m)                 { _matcher = m; }
//void          set_regalloc(PhaseRegAlloc*VM
  int               code_size()                 { return _method_size; }
  CodeBuffer*       code_buffer()               { return &_code_buffer; }
  int               first_block_size()          { return _first_block_size; }
  void              set_frame_complete(int off) { if (!in_scratch_emit_size()) { _code_offsets.set_value(CodeOffsets::Frame_Complete, off); } }
  ExceptionHandlerTable*  handler_table()


All organizations, whether large or small, rely on accountants to record and report the activities of the business.

The curriculum is tailored to expose students to specific areas of accounting, including:

Internal Audit

Federal Tax Accounting

Business Law for Management,

Business Ethics and Corporate Governance

Financial Accounting Theory

Electives are also offered in:

Advanced Financial Accounting

Not-for-Profit Accounting

Advanced Management Accounting

Accounting Systems Control

Business Valuation

Sykes College of Business

Sykes College of Business is an integral part of a 100-acre university campus nestled in the heart of Tampa. As a comprehensive institution, The University of Tampa provides a full spectrum of resources, qualified faculty and modern facilities.

The Sykes College of Business is one of the elite private schools in the Southeast accredited at both the graduate and undergraduate levels by AACSB International – The Association to Advance Collegiate Schools of Business.Four-dimensional structure underlying scales for depression anxiety and retardation: emergence of trapped anger and scale improvements.
Improvement of rating scales for anxiety and depression has insufficiently been based on their underlying multidimensional structure. The aim of this study was to detect the underlying symptom structure of 3 scales for anxiety, depression, and retardation from the Comprehensive Psychopathological Rating Scale (CPRS), to test its validity, and to investigate whether the scales developed from this structure have lower item overlap than the original scales. All items (N = 21) of the 3 subscales (Brief Anxiety Scale [BAS], Montgomery Asberg Depression Rating Scale [MADRS], and Motivational Inhibition) were selected. Principal components analysis was performed on the scores of 334 outpatients. Correlations between factor-regression scores on the CPRS components and scores on the


'Plugin Editor' ), 'edit_plugins', 'plugin-editor.php' );

$menu[25] = array( __( 'Settings' ), 'manage_network_options', 'settings.php', '', 'menu-top menu-icon-settings', 'menu-settings', 'dashicons-admin-settings' );
if ( defined( 'MULTISITE' ) && defined( 'WP_ALLOW_MULTISITE' ) && WP_ALLOW_MULTISITE ) {
	$submenu['settings.php'][5]  = array( __( 'Network Settings' ), 'manage_network_options', 'settings.php' );
	$submenu['settings.php'][10] = array( __( 'Network Setup' ), 'setup_network', 'setup.php' );
}
unset( $update_data );

$menu[99] = array( '', 'exist', 'separator-last', '', 'wp-menu-separator' );

require_once( ABSPATH . 'wp-admin/includes/menu.php' );
methanol for 72 h to obtain the extract. The extract was filtered and evaporated to dryness under reduced pressure on a rotary evaporator. The yield of methanolic extract of *M. alba* L. (MAE) leaves was found to be 2.2% w/w. Before use, the extract was dissolved in distilled water for administration intraperitoneally (i.p.).

Phytochemical screening {#sec2-2}
-----------------------

Phytochemical investigation of the extract for the presence of phenolic compounds, flavonoids, tannins, triterpenes, anthocyanins, anthroquinones, and sterols was carried out using the methods previously described by Kokate (1994) and Trease and Evans (1997). The presence of alkaloids and saponins was also ascertained.

Animals {#sec2-3}
-------

Albino male Swiss mice (18-22 g) were used for the study. The animals were housed in colony cages and maintained under standard environmental conditions: 25 ± 2°C temperature, 12:12 h light:


were counted for 5 min. Diazepam (1 mg/kg, i.p.) was used as the positive control drug.\[[@CIT9][@CIT11]\]

### Light/dark exploration test: {#sec3-4}

The apparatus consisted of two boxes (25 × 25 × 25 cm) joined together. One box was made dark by covering its top with plywood, whereas a 40-W lamp illuminated the other box. The light source was placed 25 cm above the open box. The mice were placed individually in the centre of the lit box and observed for the next 5 min for the time spent in the lit and dark boxes. The mice were treated with MAE (50, 100, and 200 mg/kg), diazepam (1 mg/kg, i.p), or vehicle 30 min before being placed in the lit box.\[[@CIT12]\]

### Locomotor activity: {#sec3-5}

The locomotor activity was measured using an actophotometer.at all doses. The reference standard (diazepam, 1 mg/kg, i.p.)-treated group showed significant increase in exploratory activity (*P* \< 0.01) \[Figure [1A](#F0001){ref-type="fig"} and [B](#F0001){ref-type="fig"}\].

![Effect of MAE on (A) number of head poking and (B) duration of head poking in mice. Each column represents mean ± SEM (*n* = 6). \*\**P* \< 0.01 vs vehicle (one-way ANOVA followed by Dunnett\'s test)](IJPharm-40-32-g001){#F0001}

Elevated plus-maze test {#sec2-11}
-----------------------

The vehicle-treated mice spent 30.8 ± 6.4 s in the open arm and 243.5 ± 8.0 s in the closed arm, with 8.3 ± 1.2 entries into the open arm and 14.7 ± 1.0 entries into the closed arm. MAE (100 and 200 mg/kg) and diazepam (1 mg/kg) induced significant (*P* \< 0.01) increase in the occupancy in the open arm. MAE in the dose of


                243.5 ± 8.8                                        8.3 ± 1.26                                       14.7 ± 1.0
  Diazepam (1 mg/kg, i.p.)   107.0 ± 12[\*\*](#T000F1){ref-type="table-fn"}    169.0 ± 13.1[\*\*](#T000F1){ref-type="table-fn"}   20.5 ± 1.9[\*\*](#T000F1){ref-type="table-fn"}   9.7 ± 0.9
                        13.2 ± 1.2                                       125.2 ± 7.5[\*\*](#T000F3){ref-type="table-fn"}
  MAE (100 mg/kg, i.p.)      22.5 ± 4.5[\*\*](#T000F3){ref-type="table-fn"}   20.5 ± 1.8[\*](#T000F2){ref-type="table-fn"}     140.5 ± 8.2[\*\*](#T000F3){ref-type="table-fn"}
  MAE (200 mg/kg, i.p)       30.3 ± 2.5[\*\*](#T000F3){ref-type="table-fn"}   20.8 ± 2.0[\*](#T000F2){ref-type="table-fn"}     158.7 ± 8.1[\*\*](#T000F3){ref-type="table-fn"}

*n* = 6;

*P* \< 0.05,

*P* \< 0.01 *vs* vehicle (one-way


that is generated by fear of open spaces. Drugs that increase open arm exploration are considered as anxiolytics and the reverse holds true for anxiogenics.\[[@CIT17]\] In our study, we observed that MAE (100 and 200 mg/kg) induced significant increases in the both the number of entries and time spent in the open arms. The number of entries and the time spent in the closed arms were reduced in the extract-treated group as compared to the control group. The results obtained in the open field test showed that MAE administration significantly increased rearing, assisted rearing, and number of squares traversed, which supports the anxiolytic-like activity of MAE.

The light and dark paradigm is based on the natural aversion of mice to brightly lit places. Anxiolytics reduce the natural aversion topharmacology suggest that plants containing flavonoids, saponins, and tannins possess activity against many CNS disorders.\[[@CIT11]\] Photochemical tests of MAE revealed the presence of flavonoids, tannins, and saponins. It is possible that the mechanism of anxiolytic action of MAE could be due to the binding of any of these phytochemicals to the GABA~A~-BZD complex. In support of this, it has been found that flavones, which are present in *M. alba*, bind with high affinity to the BZD site of the GABA~A~ receptor.\[[@CIT10]\]

The results obtained in this study suggest that the extract of the leaves of *M. alba* possesses anxiolytic and muscle-relaxant activities, which is possibly mediated through the GABA~A~-BZD mechanism. Thus, *M. alba* L. has potential clinical application in the management of anxiety and muscle tension disorders. Further investigation


South Dakota Public Broadcasting reports Cooper had a 43-11 record at Heelan High School in Sioux City before going to USD in 1975.

He coached the 1978 Coyotes to the school’s first North Central Conference championship in 27 years.

Cooper stepped down after that season to serve full time as athletic director before serving in that capacity at Indiana State University.

“We lost a great Coyote this weekend in Beanie Cooper,” said David Herbster. “Beanie was part of a transformational time at USD and his legacy will live on here in the players he coached and the lives he touched.”Feelings of Ineffectiveness

I am 39 years old. I am married to a wonderful woman that I love with all my heart. I have two pre-teen children that are brilliant and amazing and difficult all at the same time. I have a decent job, a mortgage that we were behind on but are finally catching up on. Some credit card debt and a couple of hundred bucks in the bank.

My wife doesn’t have lots of beautiful jewelry or beautiful clothes, my kids have enough clothes to get them through but lots of toys (at this point in their lives “toys” refers to xbox, computer, cell phone, etc… not exactly a tonka truck if you know what I mean). Our family vacation this year will probably involve visiting a brother-in-law


0.001). In the AAST1 study, all patients were managed with open repair, whereas in the AAST2 study only 35.2% were managed with open repair and the remaining 64.8% were managed with endovascular stent-grafts. In the patients managed with open repair, the use of bypass techniques increased from 64.7% to 83.8%. The overall mortality, excluding patients in extremis, decreased significantly from 22.0% to 13.0% (p = 0.02). Also, the incidence of procedure-related paraplegia in patients with planned operation, decreased from 8.7% to 1.6% (p = 0.001). However, the incidence of early graft-related complications increased from 0.5% in the AAST1 to 18.4% in the AAST2 study. Comparison between the two AAST studies in 1997 and 2007 showed a major shift in the diagnosis of the aortic injury, with the widespreadarray-like
    prediction : array-like
    p : array-like
        Treatment policy (probability of treatment for each row).
    scoring_range : 2-tuple
        Fractional range over which frost score is calculated. First element
        must be less than second, and both must be less than 1.

    Returns
    -------
    scores : dict
        A dictionary containing the following values. Each is also appended
        with `_cgains` and `_aqini` for the corresponding values for the
        cumulative gains curve


= qini_riemann - 0.5*overall_lift
    practical_qini_max = practical_qini_riemann - 0.5*overall_lift

    # The predicted Qini curve.
    # First we need to reorder the y values and y_pred based on this reordering
    # We calculate TOT roughly here so we have a way of distinguishing those that (ordered, treated) and those that (ordered, untreated).
    y = (2*treatment - 1)*outcome

    def sortbyprediction(vec):
        list2 = list(zip(prediction,vec))
        # Sort by prediction.
        list2.sort(key=lambda tup: tup[0], reverse=True) # included the tup[0] because otherwise we run into problems when there are only a few predicted values -- it+= 0.5*(1/p_ordered[i])
            else:
                nt0 += 0.5*(1/(1-p_ordered[i]))

            if method=='qini':
                uplift_next = nt1o1/Nt1-nt0o1/Nt0
            elif method=='cgains':
                uplift_next = (nt1o1/nt1-nt0o1/nt0)*(nt1+nt0)/N
            elif method=='aqini':
                uplift_next = nt1o1/Nt1-nt0o1*nt1/(nt0*Nt1 + EPS)


   scores['Q_practical_max'] = practical_qini_max
    if (plot_type=='qini') or (plot_type=='all'):
        # Qini curve scores.
        scores['Q_qini'], scores['max_qini'] = auc(method='qini')
        scores['q1_qini'] = scores['Q_qini']/scores['Q_max']
        scores['q2_qini'] = scores['Q_qini']/scores['Q_practical_max']
    if (plot_type=='cgains') or (plot_type=='all'):
        # Scores for cumulative gains curve.
        scores['Q_cgains'], scores['max_cgains'] = auc(method='cgains')
        scores['q1_cgains'] = scores['Q_cgains']/scores['Q_max']
        scores['q2_cgains'] = scores['Q_cgains']/scores['Q_practical_max']
    if (plot_type=='aqini') or (plot_type=='all'):
        # Scores for adjusted qini curve.
  = np.ones(self.prediction.shape)*p
        else:  # If array.
            self.p = _ensure_array(p)

        plot_types = ['qini', 'aqini', 'cgains', 'cuplift', 'uplift', 'balance']

        # Counts.
        Nt1o1, Nt0o1, Nt1o0, Nt0o0 = _get_counts(self.treatment, self.outcome, self.p)
        self.N_treat = Nt1o0 + Nt1o1
        self.N_contr = Nt0o0 + Nt0o1
        self.N = self.N_treat + self.N_contr

        # Calculate maximal curves.
        count_functions = [_get_overfit_counts, _get_no_sure_thing_counts, _get_no_sleeping_dog_counts]


 plot_type : string, optional
            Either 'qini', 'aqini', 'uplift', 'cuplift', or 'balance'.
            'aqini' refers to an adjusted qini plot, 'cuplift' gives a
            cumulative uplift plot. 'balance' gives the test-control balance
            for each of the bins. All others are self-explanatory.
        ax: matplotlib.axes._subplots.AxesSubplot, optional
            A matplotlib axis referencing where to plot.
        show_theoretical_max: boolean, optional
       oh, just a general question how do we know when to stop using the chain rule like in that question

the chain rule says: ........we take the derivative of the inside function once. we don't take the derivative of the derivative of g(x) (that would be g''(x), and that's not in the formula). (the only time we may have to do that is if g(x) itself is a composite function, which was not the case here)

the chain rule says: ........we take the derivative of the inside function once. we don't take the derivative of the derivative of g(x) (that would be g''(x), and that's not in the formula). (the only time we may have to do that is if g(x) itself is a composite function, which was not the


see if the module is there. Move script1.py down a level, make sure you have an __init__.py and it will work.
└── root
    ├── script1.py
    │
    └── folder2
        ├── __init__.py
        ├── module1.py

You could also have script1.py insert its grandparent directory into sys.path. But really the best way to solve the problem is to make the package installable by adding a setup.py. An extremely primitive version is
import setuptools

setuptools.setup(
    name="Foobar",
    packages=setuptools.find_packages(),
    scripts=["folder1/script1.py"]
)

and your directory can be
└── root
    ├── setup.py
    ├── folder1
    │   ├── script1.py
 one line.

Having more than one \corr{a}{correction} in \corr{a}{one} line causes them to overlap. Some more random text to show that the annotations are really in the \corr{b}{margin}.

\end{document}

And the output:

A:

You can add another argument for \corr which control \marginparsep and reset it's default value. If the marginnote is not the last in current line you must add add to corr command like this \corr[add]{a}{text}
\documentclass[]{article}
\usepackage{xstring}
\usepackage{marginnote}
\usepackage{tikz}

\newcounter{correctioncounter}

\newcommand{\corr}[3][]{%
    \refstepcounter{correctioncounter}%
    \IfEqCase{#2}{
        {a}{{\color{red}#3\marginnote{%
                    \begin{tikzpicture}%
                    \draw node[draw,inner sep=2pt] {\tiny \arabic{correctioncounter}};


a brain region causes brain damage and triggers sterile inflammation and innate immune responses \[[@CR5], [@CR26]\] that are considered as putative targets for therapeutic intervention \[[@CR4]\]. While the responses of microglia to ischemic stroke have been extensively studied \[[@CR33]\], those of BAMs remain largely unknown. Nevertheless, BAMs might be important in cerebrovascular diseases because they are located at the interface between the blood vessels, the brain parenchyma, and the immune system. In humans \[[@CR28]\] and rats \[[@CR34]\], perivascular and meningeal macrophages have been classically characterised by the expression of CD163, a membrane scavenger receptor belonging to the cysteine-rich superfamily \[[@CR31]\] that is involved in the response to inflammation \[[@CR10]\]. In this study, we investigated the phenotype and function of CD163^+^ BAMs in the acute phase of cerebral ischemia/reperfusionthe brain tissue. The brain was kept in 4% PFA overnight at 4 °C, washed in phosphate buffer and embedded in paraffin. Immunohistochemistry was carried out in 5 μm-thick paraffin section with the following primary antibodies: a mouse monoclonal antibody against CD163 (clone ED2, which recognizes the rat CD163 cell surface glycoprotein \[[@CR7]\]) (\# MCA342GA, 0.5 mg/mL, AbD Serotec, Bio-Rad) diluted 1:50, and rabbit polyclonal antibodies against Iba-1 (\# 019--19,741, 0.5 mg/mL, Wako Chemicals USA, Inc.) diluted 1:500, and against myeloperoxidase (MPO) (\# A0398, 3.3 mg/mL, Dako), diluted 1:100, using the EnVisionTM Detection System; (\# K5007, Dako). Following incubation with biotinylated secondary antibodies (anti-rabbit made in goat \# BA-1000; and anti-mouse made in horse \# BA2001; both from VECTOR and used at 1:200 dilution), the immunoreaction was visualized with the avidin-biotin peroxidase


in BAMs than microglia, with the exception of some genes like *Ccl17* that was induced after ischemia in BAMs but not microglia. Two-way ANOVA followed by the Bonferroni test, \**p* \< 0.05 and \*\**p* \< 0.01 microglia vs. BAMs

The analysis of biological significance was based on enrichment analysis on different annotation databases to highlight biological categories in which the selected genes appear to be over-represented after brain ischemia. The GO analysis identified over-representation, enriched KEGG entities and clusters for terms related to *acute inflammatory response, cytokine activity, chemokine activity, response to hypoxia, extracellular space, extracellular matrix, metalloproteinases, collagen degradation, blood vessel remodelling, angiogenesis,* and *response to oxidative stress*, amongst others (see Additional file [1](#MOESM1){ref-type="media"}: Figure S3 for heat maps of genes in GO-terms representative of the inflammatory response). Down-regulated KEGG pathways included:[7b](#Fig7){ref-type="fig"}). In contrast to the effect on granulocyte recruitment, BAM depletion did not significantly modify the numbers of T cells, NK cells, or myeloid mononuclear cells infiltrating the ischemic tissue (Additional file [1](#MOESM1){ref-type="media"}: Figure S8).Fig. 6Effects of BAM depletion on leukocyte infiltration after brain ischemia. Rats received clodronate (CL) or vehicle (V) liposomes in the left ventricle 4 days before occlusion of the right middle cerebral artery and the brain was analyzed 1 day after ischemia. **a**) mRNA was extracted from the contralateral (control) and ipsilateral (ischemic) brain hemispheres of rats treated with V (*n* = 7) or CL (*n* = 6) for qRT-PCR analysis. Values are expressed as fold versus the mean value in the control V group. CL does not reduce leukocyte chemoattractants that were upregulated by ischemia in CD163^+^ macrophages (see


Fig. [3](#Fig3){ref-type="fig"}), such as *Spp1, C1qbp, Il6,* and *Ccl17*. **b**) Flow cytometry analysis of the brain hemisphere of control rats (*n* = 11 vehicle, V; *n* = 9 CL) and ischemic rats (*n* = 12 V; *n* = 11 CL) illustrates leukocyte infiltration in the ischemic group. **c**) Depletion of CD163^+^ macrophages (CL group) reduces the percentage of REA535^+^ granulocytes in the infiltrating myeloid cell population (CD45^hi^CD11b^+^) (\**p* = 0.039)Fig. 7Depletion of BAMs reduces granulocyte infiltration in the ischemic cortex. Rats received clodronate (CL) or vehicle (V) liposomes in the left ventricle 4 days before occlusion of the right middle cerebral artery and the brain was analyzed 1 day after ischemia. **a**) Myeloperoxidase (MPO) immunohistochemistry (brown, arrows) of the core of infarction in paraffin sections (counterstained with hematoxylin in blue) of ischemic rats treated with V or CL. Scale bar: 20 μm.marked in subcortical regions. We argue that the greater cortical effect might be due to the activity of subpial macrophages increasing the permeability of pial vessels in the acute phase of stroke. While we were preparing this manuscript, a study reported pathogenic actions of CD163^+^ macrophages in atherosclerosis where these cells showed activation of HIF1α and VEGF expression and increased vascular permeability and inflammatory cell recruitment \[[@CR20]\]. Interestingly, perivascular macrophages are involved in maintaining vascular barrier function in the periphery under physiological conditions \[[@CR21], [@CR24]\]. Here we show that an ischemic stroke challenge changes the homeostatic function of CD163^+^ macrophages by inducing cellular activation of the HIF pathway and generation of VEGF and inflammatory mediators. This effect in the very acute phase of stroke does not exclude putative


la Generalitat de Catalunya*. Studies complied with the "Principles of laboratory animal care" (NIH publication No. 86--23, revised 1985), and the Spanish National law (Real Decreto 53/2013). Animal work is reported according to the ARRIVE guidelines.

The brain tissue of three ischemic stroke patients who died at the Stroke Unit of Hospital Clínic de Barcelona 24 h after stroke onset was used in this study. We obtained written consent from the families for tissue removal after death for diagnostic and research purposes at the Neurological Tissue bank of the Biobank-Hospital Clínic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). The study had the approval of the Ethics Committee of Hospital Clínic de Barcelona (CEIm).

Not applicable

The authors declare that no conflict of interest exists.

Springer Nature remains neutral with regard to jurisdictional claimsa spin-echo pulse sequence, as shown in [Figure 2D](#f2-ijn-10-2579){ref-type="fig"}. Whether systemically injected nanoparticles reach the tumor site and accumulate readily is critical for cancer therapy and visualized via a clinically relevant imaging paradigm. Twenty-four hours after intravenous administration of the M-MSN_siRNA\@PEI-PEG-KALA vector, significant signal reduction (darkness) was observed around the periphery of the tumor site (the red circle region) in our orthotopic ovarian cancer model compared with the signal before injection ([Figure 4](#f4-ijn-10-2579){ref-type="fig"}). This phenomenon of nanocarrier distribution in tumor is explained due to the rare neovasculature in tumor center with high extravasation ability, overall leading to limited nanoparticles distribution in the inner necrotic zone.[@b35-ijn-10-2579],[@b36-ijn-10-2579] Accumulation of the nanocarrier in the tumor region was also confirmed by detection of iron levels using Prussian blue staining, as shown in


[Figure S5](#SD5-ijn-10-2579){ref-type="supplementary-material"}. The magnetic resonance imaging results suggest that M-MSN_siRNA\@PEI-PEG-KALA as a highly effective *T*~2~-weighted contrast agent is suitable for widespread application and could facilitate research on the optimal dosage and therapeutic window through the various dark areas in the tumor region.

Antitumor efficiency and systemic toxicity in vivo
--------------------------------------------------

On observing that the M-MSN_VEGF siRNA\@PEI-PEG-KALA delivery system achieved highly effective VEGF gene knockdown in SKOV3 cells, we then investigated whether this vector could inhibit tumor growth in vivo. Orthotopic ovarian tumor-bearing mice were created to evaluate the antitumor efficacy of M-MSN_VEGF siRNA\@PEI-PEG-KALA via inoculation of SKOV3 tumor pellets into female nude mice, as described earlier. Ten days after inoculation, the mice were treated with various vectors, including VEGF-siRNA, NC-siRNA, an empty vector, or saline, for a total of five intravenousand is an effective and a safe carrier for delivery of siRNA in the treatment of ovarian cancer.

Quantification of intratumoral VEGF content and immunohistochemistry
--------------------------------------------------------------------

The collected tumor tissues were analyzed further for intratumoral VEGF levels and MVD. As shown in [Figure 6B](#f6-ijn-10-2579){ref-type="fig"}, the average VEGF protein expression level measured by ELISA assay was inhibited by \~65% after treatment with M-MSN_VEGF siRNA\@PEI-PEG-KALA, which showed more significant knockdown efficacy than that found for the three untreated groups. Correspondingly, intratumoral VEGF and MVD were determined by immunohistochemistry analysis, represented by images of labeled VEGF proteins and CD 31-positive microvascular endothelial cells, respectively ([Figure 6A](#f6-ijn-10-2579){ref-type="fig"}). The statistical data (showing \~75% inhibition) from multiple tumor sections are shown in [Figure 6C and D](#f6-ijn-10-2579){ref-type="fig"}. Meanwhile, Ki67 expression was measured in tumor sections, and was associated


5.5-modified M-MSNs and FAM-siRNA within the pores. The distribution of siRNA and M-MSNs in the cytoplasm was also determined using confocal laser scanning microscope.

### Measurement of systemic toxicity

Measurements of markers for major nephrotoxicity and hepatotoxicity were performed on whole blood, and various biochemistry parameters were tested using the Diagnostic Auto-Biochemical Analyzer 7060 (Hitachi, Tokyo, Japan). The control group received saline without nanocarrier treatments using exactly the same regimen. All blood samples were stabilized with heparin (10 U/500 μL whole blood). For hematoxylin and eosin staining, major organs, including the heart, liver, spleen, lungs, and kidneys, were collected and fixed in 4% paraformaldehyde. Histological sections (10 μm thick) were created using a freezing microtome, stained with hematoxylin and eosin, and examined with a digital microscope (Leica).

### Prussian blue staining

TheA provision in that ballot measure allowing for automatic voting registration (AVR) would also be altered to allow people to opt-out.

Michigan voters passed the original Promote the Vote proposal by 67 to 33 percent.

Sharon Dolente, voting rights strategist at the ACLU’s Michigan chapter, told TPM that the measure was riddled with errors that could potentially create “conflicting statutes inside of [the state’s] own election code.”

“The rushed nature of all this means that you have bills that are not well drafted; they have errors in them,” Dolente said. “There are hundreds and hundreds of sections of the election code, and if you’re forgetting to deal with some of those things that need to be changed then you’re kind of creating a bigger mess.”

Another high-profile citizen-led ballot measure, which weathered


 element: 'enable',
        fields: {
            jid: JIDAttribute('jid'),
            node: attribute('node')
        },
        namespace: NS_PUSH_0,
        path: 'iq.push',
        type: 'enable',
        typeField: 'action'
    },
    {
        element: 'disable',
        fields: {
            jid: JIDAttribute('jid'),
       user would enter credentials once and then the index page with reports will show.
ReportBuilder3.0 or BIDS can easily render reports with same credentials. Also, SQL server agent runs several jobs executing SSIS packages which trigger reportingservices and they still run fine. Because these run fine I am hesitant to change settings like Service Account.
ReportService is used as a intranet reporting solution within our own domain. Configured at port 80.
I have read the following posts, but keep struggling for solution:
Similar question 1
Old solution2
Similar question 2
Link 4
Other sources:
Report Service Authentication
Service Account settings

A:

1)Change the authentication mode in rsreportserver.config to Custom
<Authentication>
   <AuthenticationTypes>
     <Custom/>
    </AuthenticationTypes>
   <EnableAuthPersistence>true</EnableAuthPersistence>
  </Authentication>

2)Change the Authentication mode in web.config file in ReportServer to None. Also


After last year I had almost given up on these things. But then this happened. I'm still hyped as Shit. I'm gonna have a lot of nice evenings with this one.

Santa,if you read this. I love ya <3four with F3-4, designated as advanced HCV disease (Table [1a](#T1){ref-type="table"}). Total RNA from frozen liver tissues was extracted in TRIzol reagent (Invitrogen, MD, USA). The extract was made DNA free by digestion with RNase-free DNase (Invitrogen, MD, USA) using 0.2 U/1 μg RNA and incubation at 37°C for 10 to 30 minutes followed by DNase inactivation at 75°C for 5 minutes. For PCR array experiments, human cell cycle RT^2^profiler PCR array (SuperArray Bioscience, MD) was used to simultaneously examine the mRNA levels of 89 cell cycle genes (list of genes is available at <http://www.superarray.com>), including five \"housekeeping genes\" in pooled RNA samples from early and advanced HCV group. The pooled samples were prepared by mixing equal amounts of liver tissue RNA from four patients of each group. Previous


Court held that the supplemental charge was not coercive. It approved of the Allen charge, which encouraged the jurors to consider each other's views and "ask themselves whether their own views were reasonable under the circumstances." Id. at 237, 108 S.Ct. 546. Supplemental charges to encourage a verdict are permissible because "[t]he State has in a capital sentencing proceeding a strong interest in having the jury `express the conscience of the community on the ultimate question of life or death.'" Id. at 238, 108 S.Ct. 546 (quoting Witherspoon v. Illinois, 391 U.S. 510, 519, 88 S.Ct. 1770, 20 L.Ed.2d 776 (1968)). Unlike Jenkins v. United States, 380 U.S. 445, 446, 85 S.Ct. 1059, 13 L.Ed.2d 957 (1965), where the trial court told the jury "You have got toBased upon the respondent, Helayne Manco's earning capacity of a net weekly wage of $99.00, it was ordered that the said Helayne Manco be ordered to pay to the Registry of the Family Court the sum of $10.00 per week, the first payment to be made on the 5th day of June, 1978.
"3. Both of the parties, viz: Carl Manco and Helayne Manco, are mutually enjoined and restrained from disposing or alienating or in any way encumbering the jointly held real estate of the parties, located at 28 Taplow St., Warwick, R.I.
"4. The State is to record this Order.

*521 "5. At the time of the sale of the said realty, no disbursements are to be made until an application is made to the Family Court, at which time


the filing of this petition Carl was a recipient of Aid to Families with Dependent Children (AFDC) for himself and the Mancos' five children. Prior to receiving this assistance, Carl was required to execute an assignment of any right to support he may have from any person on his own behalf and on behalf of the children for whom he was requesting assistance. See Rhode Island Department of Social and Rehabilitative Services Manual, Sec. 201(C)(2) at 7 (Rev. ed. 1980).
[2]  Chapter 11 of Title 15 of the R.I. General Laws 1956 (1969 Reenactment), as enacted by P.L. 1979, ch. 260, § 2.
[3]  The reviewing justice entered a separate order concerning Helayne's appeal from the master's order. The reviewing justice vacated that part of the master's order2011 UK Open Qualifier 5

The 2011 UK Open Qualifier 5 was the fifth of eight 2011 UK Open Darts Qualifiers which was held at the Metrodome in Barnsley on Saturday 16 April.

Prize Money

Draw

References

5


How Much You Need To Expect You'll Pay For A Good operating system assignment help

How Much You Need To Expect You'll Pay For A Good operating system assignment help

It mostly features context switching, synchronization, scheduling, deadlock and processes, and threads. Processes: Processes will be the group of commands that are specified to execute a program. A approach includes a virtual address House, open up handles to system objects, a security context, a novel procedure identifier, atmosphere variables, a priority course, minimum and most Performing set measurements, executable codes and one execution thread. Thread: A thread is a sequence of commands in just a system that is usually in order for execution. Threads even have their own individual security codes for protection or for maintaining it Safe and sound.patent), which teaches that the speed of an electric appliance can be varied by using a trigger in combination with a circuit which features a rheostat.  The patent examiner was shown a copy of the patents and Skil stated that, "None of these patents in any way relate to a trigger speed control using a silicon rectifier circuit, and in particular the type of circuit which permits the operator of the tool to achieve feedback by finger control."  On April 6, 1965, the patent examiner reconsidered the Gawron application and allowed it.  The Gawron patent was issued on September 28, 1965.

12
Lucerne sought to amend its application on June 15, 1965, by adding claims which duplicated the claims allowed in the Gawron application.  On May


Whether clear, unequivocal and convincing evidence of fraud was in the record before the district court is a question of fact, not of law, and thus the determination of the district court that there was no fraud may be reversed only if clearly erroneous.  Kearney & Trecker Corp. v. Cincinnati Milacron, Inc., supra at 371; Schnadig Corp. v. Gaines Mfg. Co., supra at 392; Becton Dickinson & Co. v. Robert B. Scherer Corp., 211 F.2d 835, 838 (6th Cir. 1954).  Lucerne's contention that, upon the facts found, the district court was required to conclude that Skil committed fraud as a matter of law must be rejected.

15
The district court found that Lucerne had established neither the specific intent nor the materiality elements of the fraud defense. coronary intervention with TAXus and cardiac surgery' (SYNTAX) score ([@B18]) instead of Gensini score to assess the extent of coronary involvement. An example of this is the study performed by Chen et al., where they also supported the association between the severity of CAD and low serum vitamin D levels ([@B19]). Similar to our study, theirs contained a relatively young population; however, a large portion of their study population had severe CAD, which makes their results almost impossible to generalize for all CAD patients. An interesting, recent study by Porto CM et al. has demonstrated a significant association between vitamin D deficiency and increased risk of heart failure in the elderly ([@B20]). This can also be linked to CAD, as CAD can also lead to, or exacerbate heart


Low 25-OH-D levels are associated with increased risk and extent of premature coronary artery involvement and its severity in patients who are 50 years old or younger. If this evidence is supported by larger studies in different geographical areas, early monitoring of serum vitamin D levels and vitamin D supplementation could be of great benefit especially for patients who are already at risk for premature CAD.

The authors would like to thank the Deputy for Research and Technology of Babol University of Medical Sciences for the financial support and to the participants for their utmost participation.

Funding:
========

This paper was derived from a Post-doctoral thesis in Internal Medicine with registration No. 440 in Babol University of Medical Sciences.

Conflict of Interest:
=====================

None
battle and both teams played really hard against each other.”

Down 10-7 at halftime, the host Bishops (6-5) came out with a purpose in the second half as quarterback Neil Sanders found Colton Casper on a 35-yard post route for a touchdown to give them the 14-10 lead and they never looked back.

“In the locker room, we just talked about who wants it more, that’s how it is every game,” Alfred said. “It’s not Xs and Os, it’s who wants it more, it’s who has the bigger heart. ... It’s a great day to be a Bishop.”

“It’s about time (Sanders) threw the post route because we’ve been asking him all year to throw it and finally he threw it in the last (game),” Kinsherf noted. “He said he could


it 20-13. But Archbishop Williams recovered the onside kick attempt, which allowed the hosts to run out remainder of the contest.

“You can’t expect to win if you play undisciplined and turn the ball over,” Cardinal Spellman head coach Ron St. George said. “We don’t play well when trying to come from behind.”

Alfred’s first touchdown came from a 12-yard rush in the first quarter, which was set up by a Nick Tardanico interception on the opening drive of the game.

Coincidentally, Spellman’s lone touchdown also was set up by a turnover, as Colin Tracy recovered a fumble on Williams’ own 25-yard-line, which led to Justin Olowu getting the score from the goal line to tie it, 7-7.

Spellman had the ball right before the break, and took the lead when Anastasiafive RR Rodeo Ranch sets, and four RR Western Town sets. Roy and Dale (and Pat Brady at times) showed up in more Marx playsets than any other celebrities. Personally, I think the 60mm Dale looks pretty saucy.

We saw the other five character figures from the Zorro playset, now we have El Zorro himself. Since he's mounted on a black horse it must be Tornado. In the show he also rode a white horse named Phantom. Zorro, of course, was played by Guy Williams. Like most kids of that time I watched the show faithfully and was badly disappointed when it was canceled. Many years later, when I learned that the cancellation was due to a dispute between Disney and ABC, I was irate.

On the left is El


Commandante ( Captain Monastario, played by Britt Lomand) and on the right Sergeant Garcia (played by Disney stalwart Henry Calvin).

Zorro aired from Oct 1957 to Sep 1959 on ABC at 8 o'clock. One of the best marketing tie-ins, after the playset, was the Zorro sword. A piece of chalk could be inserted into the tip so the kids could carve a Z with their blades. I had a Zorro board game. If I'd had a sword I would have put my eye out.

Friday, September 04, 2009

From Louis Marx & Co comes this set of character figures from their Zorro playset, based on the Disney TV show. From left to right we have Bernardo, Don Diego, and Don Alejandro de la Vega. I have a partial set. My tinother things, this result implies that for the independent entries model the right-hand side of our error estimate, Eq. (\[eq:MainBound\]), is with high probability smaller than $\Sigma_{\rm min}$, if $|E| \geq Cr\alpha^{3/2} n \log n\, \kappa^4(\sigma/\Sigma_{\rm min})^2$. For the worst case model, the same statement is true if $Z_{\rm max}\leq{\Sigma_{\rm min}}/{C\sqrt{r}\kappa^2} $.

Comparison with Related Work
----------------------------

![[Root mean square error achieved by for reconstructing a random rank-$2$ matrix, as a function of the number of observed entries $|E|$, and of the number of line minimizations. The performance of nuclear norm minimization and an information theory lower bound are also shown.]{} []{data-label="fig:Comparison"}](noise.eps "fig:"){width="10.cm"} (-140,-10)[$|E|/n$]{} (-275,90)

Let us begin by mentioning that a statement analogous to our preliminary Theorem \[thm:main1\] was proved in [@AchlioptasRank]. Our result however applies to any number of revealed entries,


which implies the inequality (\[eq:EvalueBound2\]) for $d(\Xm,\Um)\le \delta = \Sigma_{\rm min}/C_0\Sigma_{\rm max}$ and $C_0$ large enough. An analogous argument proves Eq. (\[eq:EvalueBound1\]).

Proof of Lemma \[lemma:Gradient\]
---------------------------------

Without loss of generality we will assume $\delta\le 1$, $C_2\ge 1$ and $$\begin{aligned}
%
\frac{\sqrt{r}}{\eps}\, ||Z^E||_2\le \Sigma_{\rm min}\, ,\label{eq:WLOG}
%\end{aligned}$$ because otherwise the lower bound (\[eq:GradientLowerBound\]) is trivial for all $d(\Xm,\Um)\le \delta$.

Denote by $t\mapsto \Xm(t)$, $t\in[0,1]$, the geodesic on $\Manif(m,n)$ such that $\Xm(0) = \Um$ and $\Xm(1) =\Xm$, parametrized proportionally to the arclength. Let $\Whm = \dot{\Xm}(1)$ be its final velocity, with $\Whm = (\hW,\hQ)$. Obviously $\Whm\in\Tang_{\Xm}$ (with $\Tang_{\Xm}$ the tangent space of $\Manif(m,n)$ at $\Xm$) and $$\begin{aligned}
 \frac{1}{m}||\hW||^2 + \frac{1}{n}||\hQ||^2= d(\Xm,\Um)^2 , \end{aligned}$$ because $t\mapsto\Xm(t)$ is parametrized proportionally to the arclength.

Explicit expressions for $\Whm$ can be obtained in terms of $\Wm \equiv \dot{\Xm}(0)=(W,Q)$ [@KOM09]. If we letits complement, which we call *heavy couples*. In the following, we will prove that for any $x\in T_m$ and any $y\in T_n$, with high probability, the contribution of light couples, $\sum_L{x_i\tZ^E_{ij}y_j}$, is bounded by $C\sigma\sqrt{\alpha\eps}$ and the contribution of heavy couples, $\sum_{\overline{L}}{x_i\tZ^E_{ij}y_j}$, is bounded by $C\sigma\sqrt{\alpha\eps\log |E|}$. Together with Remark \[remark:discrete\], this proves the desired thesis.

### Bounding the contribution of light couples {#bounding-the-contribution-of-light-couples .unnumbered}

Let us define the subset of row and column indices which have not been trimmed as $\cA_l$ and $\cA_r$. Notice that $\cA= (\cA_l,\cA_r)$ is a function of the random set $E$. For any $E\subseteq [m]\times [n]$ and $A = (A_l,A_r)$ with $A_l\subseteq [m]$, $A_r\subseteq [n]$, we define $Z^{E,A}$ by setting to zero the entries of $Z$ that are not in $E$, those whose row index


y_j^2 \sigma^2 \right)  \label{eqn:sumjust}\\
%
& \leq & \exp \left( \frac{\eps}{\sqrt{mn}}\sum_{ij} 2 \lambda^2 x_i^2 y_j^2 \sigma^2 \right)
\leq \exp \left( \frac{\eps}{\sqrt{mn}} 2 \lambda^2 \sigma^2 \right)\end{aligned}$$

Equation (\[eqn:sumjust\]) follows by the fact that $\exp(x) \leq 1 + 2x$ for $ 0 \leq x \leq \frac{1}{2}$ which is ensured by choosing $\lambda = \frac{1}{\sigma} \sqrt{\frac{mn}{\epsilon}}$. The thesis follows from Chernoff bound after some calculus.

We can now finish the upperbound on the light couples contribution. Consider the error event in Eq. (\[eq:EventDefinition1\]). A simple volume calculation shows that $|T_m|\leq (10/\Delta)^m$. We can apply union bound over $T_m$ and $T_n$ to Eq. (\[eq:ABound\]) to obtain $$\begin{aligned}
\prob\{\cH(E,\cA)\}
 &\le& \exp{\left\{\log 2 + (1+\alpha)\left(H(\delta)\log 2 +
 \log({20}/{\Delta})\right)n -{(C-2)\sqrt{\alpha}n} \right\}} + \frac{1}{n^4} \, .\end{aligned}$$ Hence, assuming $\alpha\ge 1$, there exists a numerical constant $C'$ such that, for $C > C'\sqrt\alpha$, theto respect these local identities. “The more the economy is global, the more people need to be reassured that their roots will be respected.”

“If the UK wants to leave in an orderly manner, this treaty is the only option,” Barnier said. “If the choice is to leave without a deal – fine. If the choice is to stay in the EU – also fine.”

He also repeated negotiations on Britain’s future relationship with the EU could start immediately once the agreement was signed. “We are ready, we are waiting,” he said.

The two-times EU commissioner and former French foreign minister, is increasingly seen as the next president of European commission. “That’s not a question for today,” Barnier said.

Talking about the EU, he stressed the importance of Europe speaking with one


Q:

Angular 10 - Openlayers get map coordinates on (click)

I have an OpenLayers map in my Angular map component. I need to get the click coordinate of the map on the Angular (click) event. In Javascript is easy, just adding the following code:
map.on('click', function(evt) {
  var coordinate = evt.coordinate;
}

In Angular on the map.component.html, I added the following code:

And created the getCoord() function in my map.component.ts just like this:
getCoord(event: any){
    var coordinate = this.map.getEventPixel(event);
 }

For the same click event, javascript returns this coordinate, which is the one I need

Array [ -180047.42012573266, 5279667.9723422285 ]

But in angular, I get this one:

Array [ 480, 221 ]

Any idea of how can I get the correct coordinate using Angular, or how can I convert the second into thethe first time. Walking through OUR front door was a dream come true following a lengthy long distance relationship.

The island. That beautiful granite counter top. The island where I sat, hand addressing our wedding invitations. The island that I spent many hours at, typing up blog posts and editing photos. The island with the most perfect reflections for photos.

The mudroom, where I envisioned my future puppy living. The mudroom where he slept when we brought him home, and where he has eaten his kibble ever since.

The master bedroom. The bedroom where we hid from the world on lazy Sunday mornings. The bedroom where I walked to Ryan clutching a positive pregnancy test.

The guest room. The guest room that we jam packed with aviation decor, where friends slept when


Anonymous has no leadership that can officially do anything. Which is why Barrett himself is moving forward with the operation.

He says the 25,000 emails have been sent to Der Spiegel. And he says he’s working with CNN on a story about a district attorney that, from information gleaned from the emails, appears to be working with the Zetas. In fact, Barrett cut our conversation short because the CNN producer was ringing him on his other line.

Here is what I can report with certitude: Barrett Brown is still alive, and his bladder, for now, is empty.

Keep me up to date on the latest happenings and all that D Magazine has to offer.

Comments

I once contemptibly viewed Anonymous, WikiLeaks and other technologically savvy, but politically and civilly disobedient groups. But likewith mismatched parts are quite terrified of bored imbecilic American children with Guy Fawkes masks.

I’m sure the next time they assault a police station or a military installation (and win) they’ll be thinking of how much easier it is, rather than fighting feminine Gen Y’s Uptown Dallas. Umm yeah.

Bill Marvel

Other Bill,
Nice to know whose side you’re on.

Clay

Barrett Brown vs. The Zetas: what happens when the kids who always threaten to tell the teacher and the kids who punch them out for their lunch money grow up.

ha!

^ that made me chuckle clay,
– Since this started anonymous has realized what power they have and people underestimate how historical this is, to threaten one of the most ruthless cartel to let one of their members go or risk exposure and succeed!!??

–


:= make([]int32, 0, len(this.MyEmbeddedMap))
	for k := range this.MyEmbeddedMap {
		keysForMyEmbeddedMap = append(keysForMyEmbeddedMap, int32(k))
	}
	github_com_gogo_protobuf_sortkeys.Int32s(keysForMyEmbeddedMap)
	mapStringForMyEmbeddedMap := "map[github_com_gogo_protobuf_test_casttype.MyInt32Type]Wilson{"
	for _, k := range keysForMyEmbeddedMap {
		mapStringForMyEmbeddedMap += fmt.Sprintf("%v: %v,", k, this.MyEmbeddedMap[github_com_gogo_protobuf_test_casttype.MyInt32Type(k)])
	}
	mapStringForMyEmbeddedMap += "}"
	s := strings.Join([]string{`&Castaway{`,
		`Int32Ptr:` + valueToStringCasttype(this.Int32Ptr) + `,`,
		`Int32:` + fmt.Sprintf("%v", this.Int32) + `,`,
		`MyUint64Ptr:` + valueToStringCasttype(this.MyUint64Ptr) + `,`,
		`MyUint64:` + fmt.Sprintf("%v", this.MyUint64) + `,`,
		`MyFloat32Ptr:` + valueToStringCasttype(this.MyFloat32Ptr) + `,`,
		`MyFloat32:` + fmt.Sprintf("%v", this.MyFloat32) + `,`,
		`MyFloat64Ptr:` + valueToStringCasttype(this.MyFloat64Ptr) + `,`,
		`MyFloat64:` + fmt.Sprintf("%v", this.MyFloat64) + `,`,
		`MyBytes:` + valueToStringCasttype(this.MyBytes) + `,`,
		`NormalBytes:` + valueToStringCasttype(this.NormalBytes) + `,`,
		`MyUint64S:` + fmt.Sprintf("%v", this.MyUint64S) + `,`,
		`MyMap:` + mapStringForMyMap + `,`,
		`MyCustomMap:` + mapStringForMyCustomMap + `,`,
		`MyNullableMap:` + mapStringForMyNullableMap + `,`,
		`MyEmbeddedMap:` + mapStringForMyEmbeddedMap + `,`,
		`String_:` + valueToStringCasttype(this.String_) + `,`,
		`XXX_unrecognized:` + fmt.Sprintf("%v", this.XXX_unrecognized) + `,`,
		`}`,
	}, "")
	return s
}
func (this *Wilson) String() string {
	if this == nil {
		return "nil"
	}
	s := strings.Join([]string{`&Wilson{`,
		`Int64:` + valueToStringCasttype(this.Int64) + `,`,
		`XXX_unrecognized:` + fmt.Sprintf("%v", this.XXX_unrecognized) + `,`,
		`}`,
	}, "")
	return s
}
func{
					return io.ErrUnexpectedEOF
				}
				b := dAtA[iNdEx]
				iNdEx++
				v |= (int32(b) & 0x7F) << shift
				if b < 0x80 {
					break
				}
			}
			m.Int32Ptr = &v
		case 2:
			if wireType != 0 {
				return fmt.Errorf("proto: wrong wireType = %d for field Int32", wireType)
			}
			m.Int32 = 0
			for shift := uint(0); ; shift += 7 {
				if shift >= 64 {
					return ErrIntOverflowCasttype
				}
				if iNdEx >= l {
					return io.ErrUnexpectedEOF
				}
				b := dAtA[iNdEx]
				iNdEx++
				m.Int32 |= (int32(b) & 0x7F) << shift
				if b < 0x80 {
					break
				}
			}
		case 3:
			if wireType != 0 {
				return fmt.Errorf("proto: wrong wireType = %d for field MyUint64Ptr", wireType)
			}
			var v github_com_gogo_protobuf_test_casttype.MyUint64Type
			for shift := uint(0); ; shift += 7 {
				if shift >= 64 {
					return ErrIntOverflowCasttype
				}
				if iNdEx >= l {
					return io.ErrUnexpectedEOF
				}
				b := dAtA[iNdEx]
				iNdEx++
				v |= (github_com_gogo_protobuf_test_casttype.MyUint64Type(b) & 0x7F) << shift
				if b < 0x80 {
					break
				}
			}
			m.MyUint64Ptr = &v
		case 4:
			if wireType != 0 {
				return fmt.Errorf("proto: wrong wireType = %d for field MyUint64", wireType)
			}
			m.MyUint64 = 0
			for shift :=


accepted into the "soul" of trot is down to the listeners of tomorrow looking back, in my opinion. From the perspective of the late 2010s, it is still a living genre, but one with considerable influence for the older generation and relatively little for the younger generation.

they’re saying,” Herring’s nephew Nicholas Herring stated in an interview with The St. Louis Post-Dispatch. “Kenny was just kind, caring and hilarious.”

Friends and family are still reeling from this loss and trying to make sense of what happened, as well as the added horrific shock of the vigil’s attacker.


as "jurisdictional," but nonetheless do not defer to this dictum in the Court's opinion.3   See United States v. Dean, 752 F.2d 535, 539 n. 6 (11th Cir.1985).

15
We observe, initially, that the reasonable time rule followed by these other circuits conflicts with the plain language of Rule 35(b), which speaks in terms of a court's power to act within 120 days of sentencing, dismissal of appeal or denial of certiorari.   See United States v. Kajevic, 711 F.2d 767, 768 (7th Cir.1983);  United States v. Inendino, 655 F.2d 108, 109 (7th Cir.1981).   See also United States ex rel. Quinn v. Hunter, 162 F.2d 644, 647-48 (7th Cir.1947) (decided under the previous sixty-day rule).  The Advisory Committee's Notes to Rule 35, in addition,suggest that the 120-day time limits set forth in Rule 35 refer to the time during which a court must decide any timely-filed Rule 35(b) motions.  The Notes explain, for example, that the Supreme Court promulgated Rule 35's time limitations in order to "introduc[e] a flexible time limitation on the power of the court to reduce a sentence, in lieu of the [previous] limitation of the term of court."    FED.R.CRIM.P. 35 advisory committee note.  The term of court limitation signified a termination of the judge's power to reduce a defendant's sentence at the end of the term during which the defendant's sentence was imposed.   See United States v. Benz, 282 U.S. 304, 306-07, 51 S.Ct. 113, 113-14, 75 L.Ed. 354 (1931).


F.2d 1287, 1289 (4th Cir.1975)).  In other words, the 120-day time limitation guarantees that sentencing judges will not usurp the function of the parole authorities in determining when an incarcerated defendant's progress in rehabilitation justifies an early release from prison.  The Supreme Court emphasized the importance of this separation of powers between the sentencing judge and the parole authorities in United States v. Addonizio, 442 U.S. 178, 99 S.Ct. 2235, 60 L.Ed.2d 805 (1979), where the Court stated:Congress has decided that the [Parole] Commission is in the best position to determine when release is appropriate, and in doing so, to moderate the disparities in the sentencing practices of individual judges....  The import of this statutory scheme is clear:  the judge has no enforceable expectations We voice no opinion as to what action the district court should take, if any, if a motion is filed.

39
United States v. Gaertner, 705 F.2d 210, 219 n. 3 (7th Cir.1983).  Other than counsel's statement, advanced for the first time on appeal, we find no indication in the record that defendant could have relied on footnote three in filing his Rule 35 motion in this case.  We note, moreover, that this court's opinion in Kajevic was issued approximately six months before the Supreme Court denied defendant's petition for certiorari, and that the Kajevic opinion was issued subsequent to footnote three.

40
Defendant additionally maintains that the district court could not apply the three-part test set forth in United States v. Cotton, 586 F.Supp. 199, 202 (E.D.Wis.1983), to


13,000 short statements drawn from Politifact and categorised into 6 different classes (pants-fire, false, barely-true, half-true, mostly-true, true).

Recent papers regarding the automated fact-checking have created data sets using information from the social media. BUZZFEEDNEWS \[[@CR11]\] contains 2,282 posts from 9 Facebook accounts of news agencies. Another data set containing posts from Facebook is Some-Like-It-Hoax \[[@CR28]\], which consists of 15,500 posts from 32 Facebook pages. These posts are labeled based on the author, and not on the information contained within the post. Similar data sets based on Twitter are PHEME \[[@CR9]\], which contains a collection of rumours and non-rumours, and CREDBank \[[@CR17]\], which consists of 60 million Tweets labeled by human annotators.

Other data sets contain whole articles instead of short sentences and posts from social media. FakeNewsNet \[[@CR24]\] containsdata, and corresponding exposure correction data.
In large scale photofinishing laboratories (hereinafter referred to as photo-lab), a great number of photographic films are automatically printed in an auto-printer after the respective photographic films are inspected by a notch puncher or a negative inspection function device. The notch puncher provides a semicircular notch to each original frame to be printed, in a conventional manner and, simultaneously, records frame specification data, including frame number data, frame position data, and exposure correction data of the frames to be printed onto a recording medium, such as a punch tape or an LSI memory card. The exposure correction data is entered for each original frame to be printed during the negative inspection process. When printing, the film to be printed and the corresponding recording


if the LSI memory card itself does not coincide with the film to be printed, then the frame specification data will not coincide with the actual frame placed in the print position.
In order to detect that the actual frame position does not coincide with the frame position data, a conventional device determines, while the film is advancing, an amount of film advancement from a splice tape to a leading notch as well as individual film advancing amounts between adjacent notches. The actual film advancing amount thus determined are then compared with the frame position data recorded in the recording medium. When the actual film advancing amount does not correspond to the frame position data, it is determined that the actual frame does not correspond to the frame specification//
//     Generated by class-dump 3.5 (64 bit).
//
//     class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2015 by Steve Nygard.
//

#import <MediaPlayer/NSObject-Protocol.h>

@class MPSwipableView, UIEvent, UIView, UIWindow;

@protocol MPSwipableViewDelegate <NSObject>

@optional
- (void)swipableViewHadActivity:(MPSwipableView *)arg1;
- (void)swipableView:(MPSwipableView *)arg1 pinchedToScale:(double)arg2 withVelocity:(double)arg3;
- (void)swipableView:(MPSwipableView *)arg1 tappedWithCount:(unsigned long long)arg2;
- (void)swipableView:(MPSwipableView *)arg1 tappedWithCount:(unsigned long long)arg2 atLocation:(struct CGPoint)arg3;
- (void)swipableView:(MPSwipableView *)arg1 swipedInDirection:(long long)arg2;
- (UIView *)swipableView:(MPSwipableView *)arg1 overrideHitTest:(struct CGPoint)arg2 withEvent:(UIEvent *)arg3;
- (void)swipableView:(MPSwipableView *)arg1 willMoveToWindow:(UIWindow *)arg2;
- (void)swipableView:(MPSwipableView *)arg1 didMoveToSuperview:(UIView *)arg2;
- (void)swipableView:(MPSwipableView *)arg1 willMoveToSuperview:(UIView *)arg2;
@end


his own, inimitable way, and in the process confronts his greatest enemy—himself. This wonderfully entertaining debut, full of vivid southern characters, announces Steve McCondichie as a writer to watch.

Naeem Murr,

winner of the Commonwealth Writers' Prize

Jesse Few, the hero of Lying for a LIving, is a great creation, a Viagra-popping traveling paper salesman with a married girlfriend, a hot ex-wife he can’t get over, troubled children and a posse of salty golfing buddies who have his back as Jesse sets out to avoid adulthood and fails, as all the good ones do. The story of his journey to save his son moves like Jesse’s pearl-colored Escalade, barreling up the shoulder past the gridlocked traffic on the interstate. I couldn’t resist it.

About the Author

After twenty-fives year peddling bulldozers around thecontrol, such as chemical vapor deposition, vacuum evaporation deposition, and cathode sputtering. Cathode sputtering is particularly desirable for producing metallic films in a method that is fast and efficient on a large scale. U.S. Pat. No. 4,166,018 to Chapin discloses a particularly useful sputtering process and apparatus which employ a magnetic field to improve cathode sputtering conditions. A sputtering apparatus is described in which a magnetic field is formed adjacent a planar sputtering surface. The field comprises arching lines of flux over a closed loop erosion region of the cathode surface.
In attempting to reproduce the properties of a wet chemical two-layer silver/copper film on glass by cathode sputtering, using known cathode sputtering techniques to produce two-layer silver/copper films at various thicknesses and thickness ratios, the desirable low reflectance


provided, as tire self-sealing layer, a rubber mixture comprising a first polymer material which decomposes when irradiated, such as polyisobutylene, and a second polymer material which crosslinks when irradiated, preferably a butyl rubber.
The document U.S. Pat. No. 4,426,468 has for its part also provided a tire self-sealing composition based on crosslinked butyl rubber having a very high molecular weight.
A known disadvantage of butyl rubbers is that they exhibit significant hysteresis losses (i.e., a high tan δ level) over a broad temperature spectrum, a disadvantage which has repercussions on the self-sealing compositions themselves with a strong increase in the hysteresis and significant penalization of the rolling resistance of the tires.
Self-sealing compositions based on an unsaturated diene elastomer (natural rubber) have also been described for the same type of application,that the Matrix $\bf{W}$ of the quadratic form $x^T {\bf{W}} x$ can be assumed to be symmetric in the following way:
In general a matrix can be decomposed into a symmetric and an anti-symmetric part as follows:
$$M = \frac{1}{2} ( {\bf{M}} + {\bf{M}}^\top) + \frac{1}{2} ({\bf{M}} - {\bf{M}}^\top) = M_s + M_a$$
Further we note that the symmetric part is invariant to the transpose,
$$ {\bf{M}}_s^\top = {\bf{M}}_s $$
while the antisymmetric part changes its sign under transposition:
$$ {\bf{M}}_a^\top = - {\bf{M}}_a$$
Let us examine the quadratic form of a purely antisymmetric matrix:
$$q = {\bf x}^\top {\bf M}_a {\bf x} = ({{\bf x}^\top {\bf M}_a^\top {\bf x}})^\top  = -({\bf x}^\top {\bf M}_a {\bf x})^\top = -q$$
Which implies that $q=0$ has to hold true.
Now for a general Matrix $\bf W$ we can see


that:
$${\bf x}^\top {\bf M} {\bf x} = {\bf x}^\top ({\bf M}_s + {\bf M}_a){\bf x} = {\bf x}^\top {\bf M}_s {\bf x} + {\bf x}^\top {\bf M}_a {\bf x}$$
As we know that $${\bf x}^\top {\bf M}_a {\bf x} = 0$$ we finally find
$${\bf x}^\top {\bf M} {\bf x} = {\bf x}^\top {\bf M}_s {\bf x}$$

division.

Pettine understands there are challenges in turning around the Browns, who have lost at least 11 games in each of the past six seasons and made the playoffs once in their expansion era. Pettine believes the Browns have talent — as evidenced by their six Pro Bowlers — and wants to be the one to return them to glory.

"There's only 32 of these jobs and they don't come along often," Pettine said. "People ask me, 'Why didn't you wait? There will be chances next year?' I don't know if I believe in that. When you put all the factors together, this franchise is in position, given the right leadership, to win."

Story continues

Pettine emerged as the favorite to become Cleveland's fourth coach in six years as the Browns eliminated


are arbitrary, and objects are equivalent if they isometric by an map that commutes with the marking, up to free homotopy. As in the special cases of $\operatorname{GL}(n,{\mathbb{Z}})$ acting on $Q_n$ and $\operatorname{Out}(F_n)$ acting on $CV_n$, $\operatorname{Out}({A_{\Gamma}})$ acts on ${\mathcal{O}_{\Gamma}}$ by changing the marking. The main theorem states,\

\[thm:main\] For any right-angled Artin group ${A_{\Gamma}}$, the space ${\mathcal{O}_{\Gamma}}$ is finite-dimensional, contractible and the group $\operatorname{Out}({A_{\Gamma}})$ acts properly.\

We now give a brief outline of the proof. The proof begins with the space $K_{\Gamma}$ which, as noted above, was shown in [@CSV] to be contractible. The passage from $K_{\Gamma}$ to ${\mathcal{O}_{\Gamma}}$ involves several intermediate steps. First, we embed $K_{\Gamma}$ into a new space ${{\Sigma}_\Gamma}$ by endowing ${\Gamma}$-complexes with metrics making “cubes" into orthotopes, i.e. orthogonal products of intervals of various lengths;(u2) at (u2) [$u_2$]{}; (u3) at (u3) [$u_3$]{}; (w1) at (w1) [$w_1$]{}; (w2) at (w2) [$w_2$]{};

Salvetti complexes
------------------

For a simplicial graph ${\Gamma}$ the [*Salvetti complex*]{} ${\mathbb{S}_{\Gamma}}$ is a cube complex with one $k$-cube for each $k$-clique in ${\Gamma}$; in particular it has a single 0-cube (for the empty clique) and a 1-cube for each vertex (=1-clique) of ${\Gamma}$. The $2$-skeleton of ${\mathbb{S}_{\Gamma}}$ is the standard presentation complex for ${A_{\Gamma}}$, so $\pi_1({\mathbb{S}_{\Gamma}}){\cong}{A_{\Gamma}}$. The addition of higher-dimensional cubes guarantees that ${\mathbb{S}_{\Gamma}}$ satisfies Gromov’s link condition, i.e. all links are flag. Therefore if all cubes of ${\mathbb{S}_{\Gamma}}$ are identified with standard Euclidean cubes $[0,1]^k$ then the induced path metric on ${\mathbb{S}_{\Gamma}}$ is non-positively curved (locally CAT(0)) and its universal cover $\widetilde{{\mathbb{S}}}_{\Gamma}$ is CAT(0). In Figure \[fig:salvetti\] we show a simple example of a


containing the terminal vertex of some (hence every) $e_v$ edge. If $[{{\mathcal Q}},{{\mathcal P}}]\neq 1$, then $H_{{\mathcal Q}}$ does not intersect $H_{{\mathcal P}}$ and the ${{\mathcal Q}}$-side of $H_{{\mathcal P}}$ is the side containing $H_{{\mathcal Q}}$.

\[prop:cube\] Let ${\Pi}$ be a compatible set of $k$ [${\Gamma}$-Whitehead]{}-partitions, and let $\mathcal A=\{A_1,\ldots, A_\ell\}$ be a maximal set of commuting labels $A_i\in V\cup{\Pi}$. Then there is a cube in ${{\mathbb{S}}^{\Pi}}$ with edge labels $\{A_1,\ldots,A_\ell\}$.

Let $v_i\in \max(A_i)$. Since the $A_i$ commute, the $v_i$ are distinct and the corresponding vertices form a clique in ${\Gamma}$. Set $\mathcal A\cap V=\{v_i,\ldots,v_r\}$ and $\mathcal A\cap {\Pi}=\{ {{\mathcal Q}}_1,\ldots,{{\mathcal Q}}_s\}$ with $r+s=\ell$. Finally, write ${\Pi}\setminus \mathcal A=\{{{\mathcal P}}_{1},\ldots,{{\mathcal P}}_t\}$ with $s+t=k$.

Since $\mathcal A$ is maximal, for each ${{\mathcal P}}_i$ there is some $A_j$ with $[{{\mathcal P}}_i,A_j]\neq 1$. Let(since there are edges labeled both ${{\mathcal P}}$ and ${{\mathcal Q}}$ at ${\mathbbm r}$). Since changing sides of $Q$ is allowed at ${\mathbbm r}'$, it follows that the side of ${{\mathcal P}}$ at ${\mathbbm r}'$ must also be equal to $P^\times$. As before, the initial edge of the path $p$ crosses $H_{{\mathcal P}}$, so in order to reach ${\mathbbm r}'$ it must cross $H_{{\mathcal P}}$ again, contradicting the assumption that it is shortest.

We conclude that $[B,{{\mathcal P}}]=1$ for all edge labels $B$ of $c$, so there is a cube $c\times e_B \subset {{\mathbb{S}}^{\Pi}}$. The side $c''$ of this cube opposite from $c$ is closer to $c'$, and we can continue to build a product neighborhood $c\times [0,n]$ until we reach $c'$.

\[fact:maxcube\] For every maximal collection $\{A_1,\ldots,A_k\}$ of pairwise


the set of maximal elements in $\operatorname{split}_h(H)$. In the next lemma we will see that the elements of $\max_h(H)$ all belong to the same fold-equivalence class and moreover, that this equivalence class is actually independent of the marking $h$ up to graph automorphisms.

\[lem:Sing\] Let $X$ be a ${\Gamma}$-complex, $h\colon X\to {\mathbb{S}_{\Gamma}}$ an untwisted marking and let $m_h$ be any element of $\max_h(H)$.

1.  If $v\in\operatorname{split}_h(H)$, then $v\leq_f m_h$.

2.  There is a ${\Gamma}$-collapse map $c$ such that $m_c \sim_f m_h$ for any $m_c \in \max_c(H).$

Thus the maximal elements in $\operatorname{split}_h(H)$ all lie in the fold equivalence class of $\max_c(H)$.

By Lemma \[lem:Gcollapse\] we can write $$h=\varphi_n\circ\ldots\circ\varphi_1\circ c$$ where $c=c_\pi i\colon X{\cong}{{\mathbb{S}}^{\Pi}}\to {\mathbb{S}}$ is a ${\Gamma}$-collapse map and each $\varphi_j$ induces an inversion, partial conjugation or elementary fold. Let $\bar h$K_{\operatorname{nl^+}(v)} }$ contains an axis for $\bar h_*(v)$ (see Corollary \[cor:ContainsAxes\]). Call this axis $\alpha^h_v$. Then ${\mathbb K_v}$ contains $\operatorname{Min}_h(v)= \alpha^h_v \times {\mathbb K_{\operatorname{lk}(v)}}$.

By assumption, the axis $\alpha^h_v$ crosses some lift $\widetilde{H}$ of $H$. Let $m \in \max_c(H)$. If $v$ is not maximal in $\operatorname{split}_h(H)$ then $v<_f m$. In this case, ${\widetilde H}$ is isomorphic to ${\mathbb K_{\operatorname{lk}(m)}}$ which is strictly bigger than ${\mathbb K_{\operatorname{lk}(v)}}$ hence $\widetilde{H}$ is not contained in $\operatorname{Min}_h(v)$.

Conversely, if $v$ is maximal, then $v \sim_f m$ and we can identify ${\widetilde H}= {\mathbb K_{\operatorname{lk}(v)}}= {\mathbb K_{\operatorname{lk}(m)}}$. It follows that the entire carrier $\kappa(\widetilde{H})$ is contained in $\operatorname{Min}_h(v)$. In addition, ${\mathbb K_{\operatorname{nl^+}(v)} }$ also contains an axis $\alpha_m$ for $m$ with respect to the marking $c$ and $\operatorname{Min}_c(m)= \alpha_m \times {\mathbb K_{\operatorname{lk}(v)}}$. Since $m \in


which goes from $x$ to an $e_u$ edge in ${\mathbb{C}^{\Pi}}$ , across $e_u$, and then back to $x$ in ${\mathbb{C}^{\Pi}}$. Note that $\xi_u$ crosses a single $e_u$ edge and all other edges are labeled by partitions. We choose $\xi_u$ to have minimal length among all such paths. $\xi_u$ represents the homotopy class $(c_\pi^{\mathcal{F}})^{-1}(u)\in \pi_1({{\mathbb{S}}^{\Pi}},x)$.

Lift $\xi_u$ to a path $\widetilde{\xi}_u$ based at $\widetilde{x}$. The endpoint $\widetilde{y}$ of $\widetilde{\xi}_u$ is then $u\cdot \widetilde{x}$ with respect to the $c_\pi^{\mathcal{F}}$-marking. Since $\xi_u$ was taken to be minimal, $\widetilde{\xi}_u$ is a combinatorial geodesic (i.e. it crosses each hyperplane in ${\widetilde{\mathbb{S}}^{\Pi}}$ at most once), and our choice of $x$ means $\widetilde{x}$ and $\widetilde{y}$ are vertices in $(\widetilde{{\mathbb{S}}}^\Omega,{\mathcal{G}})$. Any minimal length edge path $\widetilde{\eta}_u$ in $(\widetilde{{\mathbb{S}}}^\Omega,{\mathcal{G}})$ between $\widetilde{x}$ and $\widetilde{y}$ consists of edges that crosstowards $w_1$, then $w_2$, and so on. At each stage, we will verify that the resulting parallelotope structure is a skewed $\Gamma$-complex with an untwisted marking. At the final stage, we arrive at a skewed $\Gamma$-complex $(X,{\mathcal{G}})$ that differs from $({{\mathbb{S}}^{\Pi}}, {\mathcal{F}})$ by the original zero-sum shearing. This will prove the proposition.

[**Parallelotope decomposition.**]{} Assume we are shearing towards a single twist-dominant element $w$. We will define the new paralleotope decomposition by determining the hyperplanes dual to the parallelotopes. The twist-minimal hyperplanes in the structure $({{\mathbb{S}}^{\Pi}},{\mathcal{F}})$ will remain hyperplanes in the new decomposition, and we will eventually identify these with the twist-minimal hyperplanes in a new skewed ${\Gamma}$-complex structure $(X,{\mathcal{G}})$. The twist-dominant hyperplanes in $(X,{\mathcal{G}})$ with maximal element $w$ will be defined using a projection of $\operatorname{Min}(w)$ to an


the marking $c$. As seen in Proposition \[prop:uniqueness\], once we have determined the twist-minimal hyperplanes, the shearing of their dual edges together with the branch locus completely determines ${\mathcal{F}}$. Suppose $H$ is a new hyperplane, not coming from a hyperplane in ${\mathcal{F}}_0$. We are free to choose the shearing on the dual edge by any vector in $U_H^+$. Different choices will only affect the determination of twist-dominant hyperplanes. Therefore we choose the dual edge to be orthogonal to $H$, of length equal to the width of $\kappa(H)$. If $H$ corresponds to a hyperplane in ${\mathcal{F}}_0$ which is collapsed by $c_0$, we leave the shearing unchanged, but adjust the length of the dual edge to take account of the change in the width of the hyperplane carrier. Finally, forthe dynamic correction system used to offset heavy loads.:Also, the tests done in the "down" orientation show much less force, though still in the "weighs less" direction. This may be due to the better RF sealing on the fixed end which is down in the "down" orientation.


               'normalized_image' : Binary(cPickle.dumps(normalized_image, protocol=2)),
                        # other data
                       }
        records.append(this_result)

client = pymongo.MongoClient(MONGO_CREDENTIALS)
db_name = 'database_name'
client.drop_database(db_name)
database = client[db_name]
collection = database['data_sample']
collection.insert_many(records)

I've understood from ML documentation that classifiers work with vectors and matrices, defined in pyspark.ml.linalg module.
I've managed to read data from the database to the Spark DataFrame using official MongoDB Spark connector.
However, they are still serialized:
from pyspark.sql import SparkSession
import pyspark.ml as ml

spark = SparkSessionsix-year statute of limitations for these offenses, section 800, had expired by the time the complaint was filed in September 1997. The complaint charged, however, that the case was being brought pursuant to section 803, subdivision (g), which provides that when a person of any age reports to a California law enforcement agency that while he was under the age of 18, he was the victim of a crime described in section 288, subdivision (a), the People may file a criminal complaint within one year of the date of the report. (§ 803, subd. (g)(1).)

1. Alleged Improper Pleading

As a preliminary matter, appellant argues that his conviction of counts 2 and 3 must be reversed because the prosecutor did not allege the applicability of section 803, subdivision (g), to


those counts in the information. The information alleged as to count 12 that the statute of limitations was extended under section 803, subdivision (g), but there was no specific allegation as to counts 2 and 3. Counts 2 through 11 contained identical charges that appellant on or about 1990 through 1991 committed a lewd and lascivious act upon a minor under the age of 14 in violation of section 288, subdivision (a). Each count further alleged that the offense was a serious felony. Following count 11, the information alleged:
"It is further alleged that at the time of the commission of the above offenses said defendant, Robert Bruce Lamb, occupied a position of special trust, to wit: teacher, and committed an act of substantial sexual conduct, to wit: masturbationof said victim by said defendant, within the meaning of Penal Code section 1203.066(a)(9).
"Prosecution of the charged crimes is commenced pursuant to Penal Code section 803, subdivision (g). The district attorney further alleges that:
"On August 4, 1997, John Doe reported to a law enforcement agency that he, while under the age of 18 years, was the victim of a sexual crime as specified in Penal Code section 803, subdivision (g).
"The limitation period specified in section 800 and/or 801 has expired as to that crime.
"The crime involved substantial sexual conduct, to wit: masturbation of the victim by the defendant.
"There is independent evidence that clearly and convincingly corroborates the victim's allegation, to wit: four other people have been interviewed and they indicate that they too were sexually molested by the


abandonment of a known right. (Id. at p. 371, 58 Cal.Rptr.2d 458, 926 P.2d 438.)
The narrowness of the holding in Cowan was recently reaffirmed by the Supreme Court in People v. Williams (1999) 21 Cal.4th 335, 87 Cal.Rptr.2d 412, 981 P.2d 42, where the court declined to overrule the line of cases holding that the statute of limitations may be asserted at any time. The court emphasized the limited nature of the exception it had adopted in Cowan and refused to extend it to make the statute of limitations an affirmative defense. Instead, the court held that a defendant may not inadvertently forfeit the statute of limitations and be convicted of a time-barred charged offense.
The Cowan exception is inapplicable in this case. Appellant did not expressly waive thein the Assembly on January 17, 1992. (Assem. Amend, to Assem. Bill 638 (1991-1992 Reg. Sess.) January 17, 1992.) The exception for "masturbation that is not mutual" was added by the Senate on June 18, 1992, as recommended by the Senate Committee on the Judiciary. (Assem. Final Hist. (1991-1992 Reg. Sess.) p. 502.) The amendment was apparently prompted by the following comment contained in a report prepared for a June 9, 1992, hearing of the Senate Committee on the Judiciary: "Under the new exception to the statute of limitations created by this bill, the offense must involve substantial sexual conduct; this would be defined to mean penetration of the vagina or rectum by the penis of the offender or by any foreign object, oral copulation, or masturbation of


the legislative history.
Assembly Bill 638 was approved by both houses and the Governor (Assem. Final Hist. (1991-1992 Reg. Sess.) p. 502), but it never went into effect because it was joined with a second bill, Senate Bill 25, which the Governor vetoed. (Stats.1992, ch. 921, § 2, p. 4422; Sen. Final Hist. (1991-1992 Reg. Sess.) p. 34.) The final version of Assembly Bill 638 was reintroduced during the 1993-1994 legislative session as Assembly Bill 290 and was enacted at that time. (Assem. Final Hist. (1993-1994 Reg. Sess.) p. 276; Stats.1993, ch. 390, pp. 2224-2226.)
The People argue that the italicized statement in the Senate Judiciary Committee analysis leaves no doubt that the Legislature intended masturbation of the minor by the perpetrator to constitute mutual masturbation and qualify for the See also Webster's Third New International Diet, of the English Language (1965) p. 1493 [including as definitions of the word "shared in common," "enjoyed by each," and "joint"]; Webster's New World Diet, of the American Language (2d ed.1974) p. 940 ["shared in common; joint"]; 10 Oxford English Diet. (2d ed.1989) p. 155 ["pertaining to both parties; common"].
[7]  Indeed, a defendant's act of touching a child's thigh with his hand, while the defendant was masturbating, has been found to constitute a lewd act under section 288. (People v. Diaz (1996) 41 Cal.App.4th 1424, 1427-1428, 49 Cal.Rptr.2d 252; see generally People v. Martinez (1995) 11 Cal.4th 434, 452, 45 Cal.Rptr.2d 905, 903 P.2d 1037.)


Q:

Creating Data Elevation Model from two sources

I have 2 Data Elevation Models ( Aster with 30 m resolution and a DEM obtained by stereo with 4 m resolution ).
Unfortunatly the DEM with high resolution contains a lot of no data value and some values with low accuracy. So, I want to use the two DEMs and extract one DEM with high accuracy. How can I do it ?

A:

you can subsample aster to 4 m and combine both DEMs using simple IF ELSE statements.
Note that no new information will be created in the subsampling.

1. Field of the Invention
This invention relates to a hub assembly for a bicycle, more particularly to a hub assembly with a ratchet-and-pawl mechanism to drive rotation of a hub shell in a uni-direction.
2. Description of the Related Art
In U.S. Pat. No. 7,121,394 B1, the applicant discloses a bicycle hub assembly that includes a hub shell mounted rotatably on a hub axle, a ratchet-and-pawl mechanism disposed inwardly of the hub shell, a chainring carrier coupled with one end portion of the hub shell through the ratchet-and-pawl mechanism, and an annular shielding unit disposed inwardly of the hub shell to shield the ratchet-and-pawl mechanism. The ratchet-and-pawl mechanism includes a plurality of pawls received in retreat bores formed in the end portion of the hub shell, and a surrounding drive


known that they had secured his removal and continued, as part of a campaign to increase the membership of the union, to accuse him of abusing Negroes.

11
Appellant's basic complaint is that the appellees conspired to discharge him without the hearing he was entitled to under state law.  In addition to this, he contends that he was fired because he was white, rather than Negro.

12
It is on this second contention that the appellant claims that his complaint states a good cause of action under Sec. 1985(3), because he was deprived of equal protection of the law or equal privileges and immunities under the law.  The facts alleged, however, do not substantiate his claim.  It may very well be true that appellant would not have been dischargedSPF of 30 or higher.”

Patients taking hydrochlorothiazide shouldn’t stop without first seeing a doctor, Pottegard cautioned. While there are other safe, affordable options to manage high blood pressure, patients already taking hydrochlorothiazide won’t meaningfully alter their skin cancer risk by staying on the drug for a few months until a physician can advise them, he said.

“If you are at an increased risk of skin cancer, due to high exposure to sunlight, have already experienced skin cancer, or are otherwise predisposed to skin cancer, you should consider consulting your physician regarding a potential therapy shift,” Pottegard said.

SOURCE: bit.ly/2kHQG5g Journal of the American Academy of Dermatology, online December 3, 2017.