Q:

VB.NET : Split word. no delimiter

I have word : "Banana". And i want it to split into :
B
a
n
a
n
a

But how? If I don't write delimiter it gaves me error, but when i write delimiter like " " there's no useful results

A:

Try,
Dim test = "Banana"

Dim ar = (From ch In test Select ch).ToArray()

For Each ch As Char In ar
   Console.WriteLine(ch)
Next

OR
Dim ar=test.AsEnumerable().ToArray()

the U.S. effort, speaking from Vienna on Wednesday about the move to convert the diplomatic post in Havana, known as the U.S. Interests Section, into a full embassy, officials said. He is expected to travel to Cuba in July to oversee the embassy’s reopening.

Hoping to stock up on Cuban cigars and rum? Here’s what you need to know about the most dramatic shift to the U.S.’s Cuba policy in 50 years. Tanya Rivero reports. Photo: AP (Originally published Dec. 17, 2014)
U.S. and Cuban leaders stunned the world in December by announcing they would move to normalize relations, setting off a six-month scramble to overcome differences. They held four rounds of talks to re-establish diplomatic ties, with the last meeting in Washington in May. Cuba late that month was


What a fuckin' idiot. He's lucky he crashed into an area where a lot of people weren't seated. If he had landed on several people that could've been really, really bad. I hope that guy is banned from that stadium for life.

What a fuckin' idiot. He's lucky he crashed into an area where a lot of people weren't seated. If he had landed on several people that could've been really, really bad. I hope that guy is banned from that stadium for life.

It was really bad. Unless I'm thinking of something else, a person he landed on had a broken neck. Of course the guy who fell was fine.

Oh, on another viewing I saw that he did knock a guy near the end as he was falling. TheAustralian Cardinal George Pell has been removed from his role as one of the Vatican's key advisors as Pope Francis moves to distance himself from the controversial figure.

Pell last year took an indefinite leave of absence from his job as the Vatican’s economy minister to defend himself from prosecution for historical child sexual offences.

Francisco Javier Errázuriz of Chile - also the subject of allegations related to sexual abuse,- has also been removed from C-9, a prominent advisory group, Reuters reports.

Pell is the highest-ranking Catholic official in the world to be facing trial over historical sexual offence allegations. In June, Pell was charged with historical sexual assault offences by Australian police in the state of Victoria. Pell denies all the allegations.

Pope Francis and Cardinal Pell, described by some as


in Germany’s ambitious goal of having renewable energy sources account for 65% of their energy output by 2030.

Come February, the German coal commission will be presenting its plan to phase out coal energy for good.

Power Up With Positivity By Sharing The Good News With Your Friends On Facebook – Photo by Vince O’Sullivan, CCconsistent with the loss of an inhibitory signaling pathway during development of galpha9 null cells. Cells expressing constitutively activated Galpha9 are defective in cAMP signaling center formation and development at low cell density and display an increased sensitivity to cAMP signal inhibition that is characteristic of enhanced suppression of the cAMP signal response. Finally, we demonstrate that galpha9 null cells, which have been codeveloped with a majority of wild-type cells, primarily establish cAMP signaling centers and are able to non-autonomously direct wild-type cells to adopt a galpha9 null-like phenotype. We suggest that Galpha9 functions in an inhibitory-feedback pathway that regulates cAMP signaling center formation and propagation. Galpha9 may be part of the mechanism that regulates lateral signal inhibition or that modulates receptor desensitization.


the second smallest value?  (a) -1  (b) s  (c) i
b
Let y = -548/3 - -181. Let g be 8/30*(-15)/(-30). What is the biggest value in y, g, -0.4?
g
Let r = 0.5 - 0.5. What is the smallest value in 1, -2, r?
-2
Let z = -68 + 62. Let o = 2/51 + 41/255. Which is the biggest value?  (a) o  (b) -5  (c) z
a
Suppose 2*n - 27 = 3*q - 3*n, -2*q + 5*n = 23. Which is the second smallest value?  (a) 3  (b) -0.09  (c) q
b
Let r = -4 - -4. Which is the biggest value?  (a) r  (b) 2  (c) -1/8
b
Let n = 1.9 - 0.4. Let q = 1.3 - n. WhichBiomimetic Phosphate-Catalyzed Pictet-Spengler Reaction for the Synthesis of 1,1'-Disubstituted and Spiro-Tetrahydroisoquinoline Alkaloids.
Tetrahydroisoquinoline (THIQ) alkaloids are an important group of compounds that exhibit a range of bioactivities. Here, a phosphate buffer-catalyzed Pictet-Spengler reaction (PSR) using unreactive ketone substrates is described. A variety of 1,1'-disubstituted and spiro-tetrahydroisoquinoline alkaloids were readily prepared in one-step and high yields, highlighting the general applicability of this approach. This study features the role of phosphate in the aqueous-based PSR and provides an atom-efficient, sustainable route to new THIQs.


a long stretch to a final release, as he has mentioned there is a lot of work to do yet. But from what I've seen so far, I'm mighty impressed. Can you imagine spending hours on an Amstrad, playing what looks like a top down Minecraft? Perhaps that will come true!Amanda Reddin

Amanda Jayne Reddin OBE  (born 6 June 1965), née Harrison, later Kirby, is a gymnastics coach, and former Olympic gymnast, for Great Britain.  Personal coach of many successful gymnasts, including three time world champion and Olympic medallist Beth Tweddle, two time Olympian Hannah Whelan and Olympian Jennifer Pinches. Reddin coached for many years at the City of Liverpool Gymnastics Club. She is now the Head National Coach for British Gymnastics.

Gymnastics career

1983 World Championships
Harrison was a member of the Great Britain team, which placed 17th, in the 1983 World Artistic Gymnastics Championships in Budapest, Hungary.

1984 Olympics
At age 19, Harrison competed at the 1984 Summer Olympics in Los Angeles in women's artistic gymnastics for Great Britain placing 7th in the team competition and 22nd in


a scribe apparatus that prevent a cutter from being bounced off a work surface by using a weight 1 and a spring 2 (the Japanese Patent Laid-open Publication No. HEI 11-157860). In this scribe apparatus, the weight 1 is provided above the scribe body 4 through the spring 2, and gravity of the weight 1 applied to the scribe body 4 prevent the cutter 3 from being bounced off the work 5. Total gravity of mass W1 of the weight 1 and mass W2 of the scribe body 2 are given to the work 5 as a static load.
However, in a way of applying the static load to the work by making the weight of the scribe body heavier, since the static load applied to the work becomesmagnetic force vibrates periodically with the scribe body vibrating periodically, magnetically repelling force seldom changes. Therefore, it is possible to apply an appropriate dynamic force to the work from the work. Also, since a spring connecting the weight with the scribe body directly is not provided, the weight will not resonate. Further, even if the cutter runs on the work, or a thickness of the work changes, or the work is undulated, since the weight moves and follows a movement of the cutter, magnetically repelling force seldom changes in these cases. It is to be noted that the dynamic load is a load applied to the work from the cutter caused by vibration of the scribe body.
In preferred embodiments, said load transmission means is composed of a pair


work from the cutter, even when the scribe body does not vibrate. And said static load originates in gravity of the scribe body and the weight.
On the occasion of cutting the work made of a hard brittle material, heightening the dynamic load and lowering the static load can form a deep scribe line on the work without damaging the work surface. According to this preferred embodiment, since the scribing apparatus comprises the static load adjustment device adjusting the static load applied to the work from the cutter, it is possible to lower the static load with the mass of the scribe body remaining heavy. Therefore, it is possible to lower the static load with the dynamic load remaining large, and to provide a scribe apparatus which is fittedcurrent research on phagocytosis of ACs in *D. melanogaster*, and which signaling pathways regulate this process, thereby giving a systematic and general overview of this process.

Signaling by ACs in Phagocytosis {#S2}
================================

Apoptotic cells generated by programmed cell death or physical wounds are quickly and silently removed, to maintain tissue homeostasis or prevent auto-inflammatory responses ([@B14], [@B15]). Once cells begin to undergo apoptosis, cell death pathway is activated, and they release multiple signaling to recruit phagocytes, which contains three steps: the release of "find me" signals, the presentation of "eat me" signals, and the removal of "don't eat me" signals ([@B16]).

At the beginning of cell death, "Find me" signals are released from ACs to promote the migration of phagocytes to ACs. Lauber firstly identified lysophosphatidylcholine (LPC) as a "find me"


and that in a *Drosophila* mutant strain with reduced level of Calr, the level of phagocytosis of ACs was about a half of that observed in wild-type embryos ([@B63]). Thus, like PS, Calr is considered as a marker for phagocytosis of ACs in *Drosophila*. Through protein pull-down analysis, Nakanishi isolated an ER protein binding to the extracellular region of Drpr, with a signal peptide at the N-terminal and an ER retention motif at the C terminal, named Prtp. They found that Prpt relocated from ER to cell surface during apoptosis in *Drosophila* S2 cells ([@B64]), and they further showed that loss-of-function of *prtp* leads to reduced level of AC clearance both by embryonic hemocytes and embryonic glia. Reexpression of *prtp* in hemocytes did not rescue this defect while     20       0/3      0/2     0/1      NA
  Xie *et al*. [10](#tca13271-bib-0010){ref-type="ref"}     Guangzhou, China        429      2        0       0        NA
  Zhou *et al*. [41](#tca13271-bib-0041){ref-type="ref"}    Guangzhou, China        27       0        0       1        7 (*P53*)


           ALK fusion        Crizotinib          1.1

PFS, progression‐free survival.

Discussion {#tca13271-sec-0015}
==========

PLELC is a rare and unique subtype of lung cancer which is associated with EBV infections and has often been identified in young non‐smokers. Since its first report in 1987, there have been around 1200 cases documented in the literature. Due to its rarity, the prevalence of driver mutation and the response of TKIs in advanced mutant patients with PLELC has not been thoroughly investigated. To the best of our knowledge, this study is the first to summarize the prevalence of *EGFR* and *ALK* alteration and the response of TKIs in PLELC. We retrospectively analyzed10 *EGFR/ALK* wild‐type PLELC patients. Therefore, this would not have affected the results of our study.

In conclusion, by reviewing the genomic profiles and clinical treatment courses of PLELC patients at our institution and in the extant literature, we found that the mutation rates of *EGFR* and *ALK* were lower than other common types of NSCLC, and *EGFR/ALK* TKIs only showed a limited response in PLELC patients with *EGFR/ALK* mutation. Further efforts are warranted to explore other molecular targets to optimize the therapeutic strategy for PLELC.

Disclosure {#tca13271-sec-0017}
==========

The authors declare that they have no competing interests.

The authors are grateful to Enago (<https://www.enago.cn/thoracic/>) for its linguistic revision. This work was supported by the following grants: Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer (No. 2017B030314120 Y Wu); Guangdong Provincial


American Sniper.jpg

Bradley Cooper in a scene from "American Sniper." (Courtesy photo | Warner Bros)

(Courtesy photo | Warner Bros)

The University of Michigan isn't the only area university whose showing of the film "American Sniper" on Friday caused controversy.

Four protesters were temporarily detained after disrupting an 8 p.m. showing of the film April 10 on the Eastern Michigan University campus, according to university officials.

EMU spokesman Geoff Larcom said during the first of two planned showings at university's Student Center, protesters got on stage and disrupted the movie.

The EMU Police Department received complaints for subjects causing a disturbance and refusing to leave at about 8:10 p.m. at the Student Center, according to their police log.

About 40 students protested the film, according to a report by the university newspaper, The Eastern Echo.

Themuch it costs, and break down if it's a good choice for you.

By Kate KnibbsProvided by

The days are shorter, groceries stores are stocked with Halloween candy, and kids are going back to school. For many Americans, this all means one thing: Football has begun. So who's going to top spot this year? W2O knows. At least, it knows who will take one kind of top spot: Most socially engaged.

The digital marketing firm is throwing its hand in the down-and-dirty NFL rankings mix – albeit it in a non-traditional way. W20 wants to rank NFL teams according to their reach, relevance, and resonance on social media. They use a proprietary algorithm that indexes social engagement scores from Facebook, Instagram, Twitter, YouTube, and elsewhere on the Web. Sports and social


chlordiazepoxide should be considered drugs of first choice. Data published in the last 10 years did not indicate an absolute contraindication in prescribing BDZs during the first gestational trimester. In any case, studies analyzed suffer from a number of methodological limitations such as lack of careful report of BDZ patterns of use in pregnancy, possible influences of recall bias, lack of controlling for confounding factors and lack of data concerning possible MMs in aborted fetuses.fewer bleeding events. The following two, large, randomized, controlled trials investigated the bleeding risk and efficacy of dual antithrombotic strategy with either rivaroxaban or dabigatran.

PIONEER AF-PCI TRIAL
====================

The PIONEER AF-PCI trial was an international, multicenter, randomized, open-label trial that enrolled 2,124 patients with nonvalvular AF who had just undergone PCI with stenting.[@B11] The overview of the study design is shown in [Table 1](#T1){ref-type="table"}. Patients with documented AF within 1 year before screening were included, but patients with AF of more than 1 year duration who received anticoagulation therapy for AF for 3 months preceding the PCI were also eligible. Major exclusion criteria were a history of stroke or gastrointestinal bleeding within 12 months and creatinine clearance less than 30 mL/min. Patients were randomly allocated to groups 1 to 3


Thromboembolic event (MI, stroke, or systemic embolism), death, unplanned revascularization

AF, atrial fibrillation; ACS, acute coronary syndrome; BMS, bare metal stent; CrCL, creatinine clearance; DAPT, dual antiplatelet therapy; DES, drug eluting stent; GI, gastrointestinal; MACE, major adverse cardiovascular event; MI, myocardial infarction; OAC, oral anticoagulation; TIA, transient ischemic attack; PCI, percutaneous coronary intervention; q.d., once a day; b.i.d., twice a day; TIMI, Thrombolysis in Myocardial Infarction; GUSTO, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries; BARC, Bleeding Academic Research Consortium; ISTH, International Society on Thrombosis and Hemostasis.

^\*^Rivaroxaban 10 mg if CrCL \<50 mL/min; ^†^Outside the United States, patients older than 80 were assigned to either group 1 or group 3. In Japan, the age cutoff was 70.

The three groups were well-matched and had around 700the use of the standard doses of dabigatran. Although the maximal duration of triple therapy was 3 months, it was still able to demonstrate significantly lower risks. The limitation of the study is that it could not evaluate the efficacy endpoints, which were not initially planned, as in the PIONEER AF-PCI trial.

FUTURE DIRECTION
================

Emerging evidence suggests that, in patients with AF who had undergone PCI, dual therapy with an NOAC is more reasonable than the conventional triple therapy by avoiding excessive bleeding events with similar efficacy. Moreover, meta-analysis of the WOEST, PIONEER AF-PCI, and RE-DUAL PCI trials demonstrated that bleeding risk was significantly lower (odds ratio \[OR\], 0.49; 95% CI, 0.34--0.72; *p*\<0.001) and incidence of MACE was comparable (OR, 0.80; 95% CI, 0.58--1.09; *p*=0.16) among the studies, further strengthening


be the first derivative of v**3/3 - v**2 + 3*v - 10. Is 3 a factor of s(4)?
False
Let a(l) = -2*l**3 - l**2 - l - 2. Let n be a(3). Let c be (-2 - n) + (2 - 2). Suppose o = 2*y + y + 12, 0 = 4*o - 3*y - c. Is o a multiple of 8?
False
Let l = -1 - -12. Let b(o) = -2*o - 6 + l*o - o**3 - 8*o**2 - o**2. Is b(-10) a multiple of 4?
True
Let j = -4 + -1. Let i = 3 - j. Suppose 5*b - i - 17 = 0. Does 2 divide b?
False
Let p = 6 + 9. Let z be 4/(-3*(-1)/p). Suppose -3*l + 5*l = z. Does 8 divide/* Copyright 2003-2008 Joaquin M Lopez Munoz.
 * Distributed under the Boost Software License, Version 1.0.
 * (See accompanying file LICENSE_1_0.txt or copy at
 * http://www.boost.org/LICENSE_1_0.txt)
 *
 * See http://www.boost.org/libs/multi_index for library home page.
 */

#ifndef BOOST_MULTI_INDEX_DETAIL_ACCESS_SPECIFIER_HPP
#define BOOST_MULTI_INDEX_DETAIL_ACCESS_SPECIFIER_HPP

#if defined(_MSC_VER)&&(_MSC_VER>=1200)
#pragma once
#endif

#include <boost/config.hpp>
#include <boost/detail/workaround.hpp>

/* In those compilers that do not accept the member template friend syntax,
 * some protected and private sections might need to be specified as
 * public.
 */

#if defined(BOOST_NO_MEMBER_TEMPLATE_FRIENDS)
#define BOOST_MULTI_INDEX_PROTECTED_IF_MEMBER_TEMPLATE_FRIENDS public
#define BOOST_MULTI_INDEX_PRIVATE_IF_MEMBER_TEMPLATE_FRIENDS public
#else
#define BOOST_MULTI_INDEX_PROTECTED_IF_MEMBER_TEMPLATE_FRIENDS protected
#define BOOST_MULTI_INDEX_PRIVATE_IF_MEMBER_TEMPLATE_FRIENDS private
#endif

/* GCC does not correctly support in-class using declarations for template
 * functions. See http://gcc.gnu.org/bugzilla/show_bug.cgi?id=9810
 * MSVC 7.1/8.0 seem to have a similar problem, though the conditions in
 * which the error happens are not that simple. I have yet to isolate this
 * into a snippet suitable for bug reporting.
 *


Missionaries or educators? Parent education for poverty families.
An adequately designed parent education program must provide answers to four central issues: (1) specification of the goals to be accomplished, (2) the message to be conveyed to the parents, (3) the most appropriate method to effect the desired change, and (4) some definitive evaluation of change related to parent participation. These four issues are considered with reference to a demonstration program of parent education for mothers of first-grade children in middle- and lower-class, white and Negro families. Implications for programs with poverty families are suggested.Primary synovial sarcoma of the kidney.
Primary renal synovial sarcomas (SS) are rare tumors of the kidney. Faria first described primary renal synovial sarcoma in 1999. Twenty-one cases of primary renal synovial sarcoma have been reported to date. Primary renal synovial sarcomas can exist in either a monophasic or a biphasic pattern. The monophasic variant of primary renal synovial sarcoma is more common and tends to have a better prognosis than the biphasic variant. We present the case of a 61 year-old woman with a monophasic variant of primary renal synovial sarcoma.


and stuff
I could see how there would be a difference in their mind
But to them, I don't think one of them takes away from the other
Yes, you do a really strong mentalism act and then throw in hippity-hop rabbits it's not gonna make sense theatrically
Yes things that might not make sense theatrical a but that doesn't mean it won't be entertaining
Well, I don't think it would either take away cuz if you've ever seen Chris Kay part
I mean, he does one of the best like fraidy-cat rabbits I've ever seen it makes me want to do the trick
Yeah, some guys that can take anything and make it amazing
So yeah, I guess the short answer is I think that of course you can yeah
Yeah, I when you're talking there
Ifirst of all what the effect is
And then figure out is it is it going to play on stage?
Like there's certain things like maybe card to pocket or card to wallet. You know that
Are kind of based on proximity, you know?
so something like that the way you can cheat is that you have to bring someone up on stage and
They have to be like the eyes and in the hands of the audience
And that's kind of what nate leipzig did he was like the first person to do close up on?
Stage because he would bring up a committee of like four people
which is basically what a lot of people do Nellie's if you watched like temari's that's basically
How he ends his you know
the first half of this show


one little thing with that one little thing
Made made the whole chicken now make sex less, you know each piece. That's usually something that's plays place for close-up or parlor. I
do uh, I
do
Maybe three different things. I do a prediction. I do the card to card to fly and then I do
Maybe maybe four things depending I'll do a cards cards across as well. And then sometimes I'll do a
tossed out deck
But I've found just just little things like if I have a card
And it's a coincidence thing, you know
they show the card that they they match I
Can make this play a lot bigger if I stand and if I hold the cards like this at the end because it's a natural
Applause q right as little things likeopens up the deck and it's in completely new deck order
So it's a kind of a fun thing talking about
Yep, there we go. There we go. No, but tons of stuff you can do there
The possibilities are endless because
Anything from doing a full deck trick to just pulling out four cards and doing a small packet thing. You know that yeah
But the possibilities are endless and really it's great for just a simple vanish, you know
Just making one card vanished. I've used the misc index. I used it IMT. I remember I did on a morning like TV spot
I was my goal was to try to make the card vanish, but I wanted to happen in his hands, you know
Yeah
All I did was basically just show him they're


thinking of a card. What is this challenge?
Uh-huh, and you can you can get pretty close to that with with the invisible deck which makes it really really awesome. Yeah
Another another great deck that has I mean too many applications to name is the marks deck and
My favorite version specifically is the the maiden marked deck that penguin put out a few years ago
Relax worked really hard on the design and things it's got six clear markings
When we used to with if you've bought a like at the dollar store if you bought a mark a marked deck
Then you see that they have like little like pin pricks and like little teeny tiny lines
So they're supposed to help you architects or you have to like literally
Yeah, yep, yepNirschl surgical technique for concomitant lateral and medial elbow tendinosis: a retrospective review of 53 elbows with a mean follow-up of 11.7 years.
Combined lateral elbow tendinosis (tennis elbow) and medial elbow tendinosis (golfer's elbow) can be a disabling condition that, if unresponsive to nonoperative treatments, may be effectively treated surgically. The authors are not aware of any study that reports the outcome of a combined operation for lateral and medial elbow tendinosis (country club elbow) performed in the same operative setting. Combined surgical treatment of country club elbow in the same operative setting has similar outcomes to those seen in the literature for single operative procedures. Case series; Level of evidence 4. Outcome measurements included the Numeric Pain Intensity Scale, the Nirschl tennis elbow scoring system, and the


Title

Author

Department

Date of Paper/Work

2016

Degree Name

Doctor of Education in Organization Development (Ed.D.)

Type of Paper/Work

Dissertation

Advisors

Alla Heorhiadi; John Conbere; Chato Hazelbaker

Abstract

Leaders constantly face the need to engage employees in the strategic direction of their organizations in order to achieve organizational goals. A core element of engaging employees involves being able to communicate strategic goals to the employees so they understand, support, and can act upon these goals. However, communicating strategic goals often falls short of these objectives. Instead, communications that convey these goals are not understood or do not seem relevant, which results in employees being disconnected, uninformed, and disengaged. Leaders often feel frustrated and confused as to why their efforts to communicate strategic goals are not effective, and they look for ways to improve their communications with employees.

The purpose of thisground by the end, with a mass exodus to both sides of us.

Also the traditional things in Pompey's authentic matchday experience, the goading of our players and abuse when taking throw ins and the comical surge in the North Stand as a small group tried to break through a bigger group of Police and then clamber across a security net to earn life long bans.

If the ground was emptying fast in the final minutes as the realisation sunk in that the game was up, it accelerated even faster when Nathan Redmond scored a corker with 4 minutes left.

There should have been only one team celebrating at the end and that was Saints, but as they headed to their supporters at the final whistle to do so, we had


obtained for the constrained Euler equations in [@RosenhausShankar], and for the Euler equations in vorticity formulation [@Oberlack2014]. On the other hand, the Euler equations in Lagrangian variables (see [@Majda; @Frisch2014] for background) do admit a variational formulation. Caviglia and Morro [@Caviglia1987] computed symmetries and conservation laws using a variational formulation for the compressible Euler equations in Lagrangian coordinates. However, they later [@Caviglia1989] computed conservation laws for the incompressible Euler equations without using symmetries or a variational formulation. We show that a simple modification to their compressible flow Lagrangian in [@Caviglia1987] allows for a variational formulation of incompressible flow.

In this paper we study a variational formulation of the incompressible Euler equations in Lagrangian coordinates. We obtain a new scaling symmetry of the action functional. This scaling symmetry leads viato a new integral quantity defined exclusively in Lagrangian coordinates. This relationship implies an inequality which shows that the total radial deformation of the fluid increases with both time and total kinetic energy. The deformation was shown to be time-irreversible, proving the non-existence of time-periodic solutions with nonzero, finite energy.

Acknowledgments {#acknowledgments .unnumbered}
===============

The author is grateful to Tucker Hartland for his contributions and to Prof. V. Rosenhaus for stimulating discussions and useful suggestions.

References {#references .unnumbered}
==========


\[[@B42-cancers-11-01903]\]. According to previous research, WISP-1 directly binds to integrin αvβ3 to activate downstream signaling proteins and stimulate cell motility \[[@B32-cancers-11-01903],[@B43-cancers-11-01903]\]. In this study, we found that the cyclic Arg--Gly--Asp (RGD) peptide, as a target epitope of integrin αvβ3, blocked WISP-1-mediated E-cadherin protein and mRNA expression. The cyclic Arg--Ala--Asp (RAD), a negative control peptide for cyclic RGD, had no effect on WISP-1-mediated E-cadherin expression ([Figure 3](#cancers-11-01903-f003){ref-type="fig"}A,B). We also found that RGD inhibited WISP-1-induced cell migration ([Figure 3](#cancers-11-01903-f003){ref-type="fig"}C). Thus, WISP-1 regulates EMT functioning via the integrin αvβ3 receptor in OSCC.

3.4. The Role of FAK and ILK Signaling Pathways in WISP-1-Activated EMT Functioning {#sec3dot4-cancers-11-01903}
-----------------------------------------------------------------------------------

Integrins mediate signaling by interacting with intracellular protein kinases, such as focal adhesion kinase (FAK) and integrin-linked kinase (ILK), transducing their intracellular signals through the cytoplasmic domain*p* \< 0.05 compared with the WISP-1-treated group.](cancers-11-01903-g003){#cancers-11-01903-f003}

![Involvement of FAK and ILK in WISP-1-regulated EMT functioning. (**A**,**B**) SCC4 cells were incubated with WISP-1 (30 ng/mL) for the indicated time intervals; FAK and ILK activation was examined by Western blot assay. (**C**,**D**) Cells were pretreated with RGD (100 nM) for 30 min then treated with WISP-1 for 10 min; FAK and ILK activation was examined by Western blot assay. FAK and GSK3β content was used to normalize for pFAK and pGSK3βlevels. (**E**,**F**) Cells were pretreated for 30 min with a FAKi (10 M) and KP392 (10 M), prior to incubation with WISP-1 for 24 h. E-cadherin expression was examined by IF and qPCR assays. (**G**) Cells were pretreated for 30 min with a FAKi (10 M) and KP392 (10


was examined by IF assay. Snail mRNA expression was examined by qPCR assay. (**H**) Cells were transfected with miR-153-3p mimic (100 nM) or control mimic (100 nM) for 24 h; cell migration was examined using the wound healing assay. Results are expressed as the mean ± SEM. \* *p* \< 0.05 compared with controls; \# *p* \< 0.05 compared with the WISP-1-treated group.](cancers-11-01903-g007){#cancers-11-01903-f007}

![A schematic model depicting how WISP-1 regulates EMT functioning in OSCC cells. The modeling shows two potential signaling pathways underlying OSCC-derived WISP-1 regulation of EMT activation: (1) WISP-1 induces Snail expression via the integrin αvβ3/FAK/ILK/Akt signaling pathway, which in turn activates EMT functioning; (2) WISP-1 also inhibits miR-153-3p-induced downregulation of Snail mRNA translation and thus stimulates Snail protein expression and EMT activation. (RGD peptide: a targetso we define $\sqrt{something}$ ONLY when $something \in \mathbb R; something > 0$.  For all other cases we just don't consider $\sqrt {-4}$ to be well defined.
.......
HOWEVER.... if we aske the question.  If $x$ is the sum of A square root of $-4$ plus A square root of $-1$ we figure:  $-4$ has two possible square roots.  One is $2i$ (because $(2i)^2 = 2^2i^2 = 4(-1) = -4$) and the other is $-2i$. But we don't refer to either of them as $\sqrt{-4}$.
And $-1$ has two possible square roots: $i$ and $-i$.
So the possible values are
$x=\begin{cases}2i + i = 3i\\-2i + i = -i\\2i -i = i\\-2i -i = -3i\end{cases}$
There are four possible values for $x$.
IF that was the question that was being asked.


of the system, are generated, and a single artificial neural network is trained to mimic this input-output relationship. An alternative approach is to first break the system into sub modules, where each individual module has a clear semantic meaning. Second, each individual module is constructed either by using a machine learning approach (e.g. the module is trained in an end-to-end manner) or by relying on manual engineering The choice of which option to use for each module is based on empirical success. We call this approach Semantic Abstraction.

To further demonstrate the two approaches, consider a simplified autonomous driving system, where a car driving in a highway should keep its lane and adapt its speed according to other vehicles. The input to the system is the sensory input (e.g.,a random choice of $x$ according to some (unknown) distribution $D$ over the domain $X$. For more details see for example [@MLbook].

We are interested in deriving lower bounds on the sample complexity. Therefore, we will consider a simpler task of just distinguishing between the two cases $\operatorname*{\mathbb{P}}[\ell(x,\hat{f}_{E2E}(x)) = 1] = 0$ or $\operatorname*{\mathbb{P}}[\ell(x,\hat{f}_{E2E}(x)) = 1] \ge \epsilon$. This is equivalent to determining whether a coin has a bias of $0$ or a bias of at least $\epsilon$, and it is well known that we should flip the coin order of $1/\epsilon$ times to distinguish between the two cases. It follows that the sample complexity of the end-to-end approach is lower bounded by $1/\epsilon$.

Getting back to our simplified autonomous driving problem, and considering the fact that the rate of


accidents for human drivers is around $3.8$ per million miles (a rough estimate based on NHTSA data for 2012), we need to set $\epsilon$ to be extremely small. The exact value depends on how we partition driving sessions into examples. For example, if each example is $0.1$ miles of driving, then we should set $\epsilon$ to be order of $10^{-7}$. If we further want to achieve super human accuracy we may want to set $\epsilon$ to orders of $10^{12}$. For a 1 Mega-pixel camera taking 36 frames per second, we end up with roughly $2^{70}$ bytes of data. As a comparison, the amount of data stored by Google, Amazon, Microsoft, and Facebook is estimated to be $2^{60}$ bytes of data.

Next, we show how we can learn with muchtheir standard sizes.

THEY NEVER LOOK UNCOMFORTABLE

Be smartnot to step outside yourcomfort zone.Thesmartest peopleknow what works for them and stick to it. You will not find them to experiment too much and will always becomfortablein what they wear. Theydress like themselves and nobody else.

1890-1920 Haute Couture

Early 90swas marked by rise ofhaute couture in Paris.TheParisian designswere donned by theupper class womenwhoset tone for rest of the world.The corsets and full skirtswithhats were popularin this era. Thefashionwhich was adopted found its way throughmagazines to the worldabout what was going on and what is being worn. But with the end ofFirst World War,the attention was withdrawn from fashion.

1920-1929 Roaring 20s

With the war taking over, masculinity was mostly retained inclothing as womenworecomfortable clothes with shapeless fits, loose clothes and flattened busts.The20sare marked by“Flappers”


and cleansethe pores which lead to black heads. Although there are many scrubs available in market but its best toavoid chemical and exfoliatethe impurities out of your skin with the natural way right from your kitchen cabinets.

For those having normal todry skin applying oats packcan be very useful.Mix spoonful ofoats and curdand thenapply this pack on face.After the pack gets dry rub the pack withfew drops of waterandthen wash it off.Your skin will not only be deeply cleaned but alsomoisturized, de-tanned and rejuvenated.

Wearing a sleeveless and a wide neck shirt in summer can lead to embarrassment because of the patchy skin which is an unwantedgift by the sun. Bequest yourbody with this scrub packwhich can be easily made at home. Take a spoon ofred lentils (masoor), spilt dehuskedblack gram lentils (dhuli urad) and rice. Soak the three in raw milk for 1-2 hours and then grind it.Add honey,few drops oflemon and rose waterin the mixture and you can apply this pack on yourface as well as body.After leaving it for few minutes gently rub your skin withfew drops of water and then finally wash it off.You will be surprised by the result and using this pack once a week can lead you tobaby soft twinkling skin.Using a toner after exfoliation followed by amoisturizeris essential for maintaining the healthy glow. You can pat your skin withrose water frequentlyto keep the pores closed andyour skin enlivened.

Sun Protection

Avoid going out in thisrising temperatureespecially between 11am to 4pm. Remember whenever you go outapply a sun screen 15 minutesprior to


your date with sun. Yoursunscreenhas to be of SPF 40 and aboveprotecting you from UVA and UVB.In case you forget to apply sunscreen, after coming back immediately massage a slice oftomato on your skin.This will not only invigorate your skin withvitamins A, C, E, K and B6but will cool down yoursunburns.With regular use you can also reduce acne scars and its appearance.

Keep an eye on what you drink and eat

Yourexternal skinis the mirror of your internal health.Therefore it is very important to maintain healthy habitsavoidingfried food and alcoholic drinks.Eating lot of fruitsand sprouts will not only keep youhydratedfrom within but also replenish your body withvital vitamins and minerals nourishing your system.Drinking 4-5 litre of water dailyis vital foryour body and shining skin.If you are addicted totea and coffeeRacing driving enthusiast Gary Barak has been crowned Person of the Year by CAT magazine, one of the leading titles in the automotive industry.

Mr Barak, 46, is the founder of Chicane, a PR and marketing firm for the motor sports and entertainment sector. Clients include Renault, Aston Martin Racing and Philips. Mr Barak, who has worked in the industry for more than 20 years, tells People: "Getting the award was a huge surprise. Usually it's me pushing the profiles of other people so it was the other way round this time."

Mr Barak, from Whitley Bay, was destined for a career involving cars. His father Philip is believed to be the oldest competitive racing driver in the country, still going at the age of 76.

Mr Barak co-founded Chicane 12


for actually forming a thin film on the surface of a substrate, a batch type apparatus that forms films on the surfaces of a plurality of substrates simultaneously is widely used.
In recent years, however, due to an increase in diameter of the semiconductor wafer as the substrate, it is difficult to maintain the film formation uniformity within the surface of the wafer or between wafers with the batch type apparatus. From this reason, in the field of semiconductor element manufacture, a single wafer processing apparatus that forms films on the semiconductor wafers one by one is used more often.
In the single wafer processing apparatus, the film formation rate must be increased to increase the throughput. In order to increase the film formation rate, it is proposed to formExcitatory and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat.
In inflamed tissue--including skeletal muscle--the concentrations of cytokines and neurotrophins are known to increase. However, nothing is known about a possible contribution of these agents to muscle pain and hyperalgesia. The present study investigated acute effects of cytokines and neurotrophins on response properties of slowly conducting muscle afferents. In anaesthetised rats, the impulse activity of single mechanosensitive group IV fibres innervating the gastrocnemius-soleus muscle was recorded and tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), nerve growth factor (NGF), or brain-derived neurotrophic factor (BDNF) were injected into the muscle. Changes in the mechanosensibility of the endings following administration of the agents were tested with repeated pressure stimuli of defined forces. A low mechanical


Trump Jr. (@DonaldJTrumpJr) May 28, 2019

Damn that was savage as hell I love it @RealJudgeMoore the sunset is waiting — Realist small (@RealistSmall) May 28, 2019

Fork him and the horse he rode in on! — Joe Gunter (@JoeGunter) May 28, 2019

This is the first time that I’ve agreed with you. — Kyle Butler (@kbutler2040) May 28, 2019

Wow, I’m actually agreeing with Jr here — MakeNDAsGreatAgain (@InsideASCIF) May 28, 2019

Just the worst candidate… Thanks for nothing Roy Moore. Do the state a favor and sit this one out… and the next one… and the next one. — CWR (@carriealmom) May 28, 2019

Amen. — Duane A. Linn (@puritan_duane) May 28, 2019

That public smack down is just awesome. He needs to go away. — Emily Miller (@EmilyMiller) May 28, 2019

I am– A Syrian opposition fighter takes a break on a mountain near a rebel camp in Idlib province on September 18.

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Syrian civil war in photos – A Free Syrian Army fighter rests inside a cave at a rebel camp in Idlib province on Tuesday, September 17.

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Syrian civil war in photos – Volunteers wear protective gear to show a class how to respond to a chemical attack in Aleppo, Syria, on September 15. For two months, Mohammad Zayed, an Aleppo University student, has been training a group of 26 civilians to respond to a chemical attack.

Syrian civil war in photos – Syrian soldiers take aim at rebel fighters positioned in the mountains of


in photos – A Free Syrian fighter mourns the death of a friend in Aleppo on March 30, in this photo taken by iReporter Lee Harper.

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Syrian civil war in photos – A Syrian opposition fighter runs for cover from Syrian army snipers in Aleppo on Wednesday, March 27.

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Syrian civil war in photos – A Syrian girl covers her face to protect herself from fumes as a street covered with uncollected garbage is fumigated in Aleppo on Sunday, March 24.

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Syrian civil war in photos – A Syrian man and his family drive past damaged buildings in Maarat al-Numan, on Wednesday, March 20.

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Syriansit underneath a washline in a refugee camp on the border between Syria and Turkey near Azaz on December 5, 2012.

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Syrian civil war in photos – The bodies of three children, who were allegedly killed in a mortar shell attack that landed close to a bakery in Aleppo, on December 2, 2012, are laid out for identification by family members at a makeshift hospital at an undisclosed location of the city.

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Syrian civil war in photos – Smoke rises in the Hanano and Bustan al-Basha districts in Aleppo on December 1, 2012 as fighting continues through the night.

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paradox is that a lot of valuable intelligence can't be used for action

We recently learned that U.S. intelligence agencies had at least three days' warning that Syrian President Bashar al-Assad was preparing to launch a chemical attack on his own people, but wasn't able to stop it. At least that's what an intelligence briefing from the White House reveals. With the combined abilities of our national intelligence apparatus -- the CIA, National Security Agency, National Reconnaissance Office and all the rest -- it's not surprising that we had advance notice. It's not known whether the U.S. shared what it knew.

More interestingly, the U.S. government did not choose to act on that knowledge (for example, launch a pre-emptive strike), which left some wondering why.

There are several possible explanations, all );
    }
});

The property folderOnClick is undefined. But I don't know how to solve this problem. Can someone point this out?

A:

In general - this is the "dynamic this" issue in JavaScript.
However, since you're using ReactJS with JSX, your code has support for ES6 arrow functions in the transform anyway:
var itemsInRepo = this.props.items.map(entry => (
   <RepositoryEntry repositoryItem={entry} folderOnClick={this.updateListFromChild} />
));

You can see the syntax on MDN for more examples.


import os
import sys

import _pytest._code
import pytest
from _pytest.debugging import _validate_usepdb_cls

try:
    # Type ignored for Python <= 3.6.
    breakpoint  # type: ignore
except NameError:
    SUPPORTS_BREAKPOINT_BUILTIN = False
else:
    SUPPORTS_BREAKPOINT_BUILTIN = True

_ENVIRON_PYTHONBREAKPOINT = os.environ.get("PYTHONBREAKPOINT", "")

@pytest.fixture(autouse=True)
def pdb_env(request):
    if "testdir" in request.fixturenames:
        # Disable pdb++ with inner tests.
        testdir = request.getfixturevalue("testdir")
        testdir.monkeypatch.setenv("PDBPP_HIJACK_PDB", "0")

def runpdb_and_get_report(testdir, source):
    p = testdir.makepyfile(source)
    result = testdir.runpytest_inprocess("--pdb", p)
    reports = result.reprec.getreports("pytest_runtest_logreport")
    assert len(reports) == 3, reports  # setup/call/teardown
    return reports[1]

@pytest.fixture
def custom_pdb_calls():
    called = []

  = 'debug' + '.me'
                    assert 0
        """
        )
        child = testdir.spawn_pytest("--pdb %s" % p1)
        child.expect("Pdb")
        child.sendline("p self.filename")
        child.sendeof()
        rest = child.read().decode("utf8")
        assert "debug.me" in rest
        self.flush(child)

    def test_pdb_unittest_skip(self, testdir):
        """Test for issue #2137"""


import pdb
            def test_1():
                pdb.set_trace()
        """
        )
        child = testdir.spawn_pytest(str(p1))
        child.expect("test_1")
        child.expect("Pdb")
        child.sendline("q")
        rest = child.read().decode("utf8")
        assert "no tests ran" in rest
        assert "reading from stdin while output" not in rest
        assertno tests ran in" in rest
        assert "BdbQuit" not in rest
        assert "UNEXPECTED EXCEPTION" not in rest

    def test_pdb_interaction_capturing_twice(self, testdir):
        p1 = testdir.makepyfile(
            """
            import pytest
            def test_1():
                i = 0
                print("hello17")


    rest = child.read().decode("utf8")
        assert "hello17" in rest  # out is captured
        assert "hello18" in rest  # out is captured
        assert "1 failed" in rest
        assert "Failed: expected_failure" in rest
        assert "AssertionError: unexpected_failure" not in rest
        self.flush(child)

    def test_pdb_without_capture(self, testdir):
        p1 = testdir.makepyfile(
            """
            import pytest
       """Full coverage for do_debug without capturing.

        This is very similar to test_pdb_interaction_continue_recursive in general,
        but mocks out ``pdb.set_trace`` for providing more coverage.
        """
        p1 = testdir.makepyfile(
            """
            try:
                input = raw_input
            except NameError:


 child.sendline("c")
        rest = child.read().decode("utf8")
        if not capture_arg:
            assert "> PDB continue (IO-capturing resumed) >" in rest
        else:
            assert "> PDB continue >" in rest
        assert "= 1 passed in" in rest

    def test_pdb_used_outside_test(self, testdir):
        p1 = testdir.makepyfile(
            """
            import pytest
        self.flush(child)

    def test_pdb_collection_failure_is_shown(self, testdir):
        p1 = testdir.makepyfile("xxx")
        result = testdir.runpytest_subprocess("--pdb", p1)
        result.stdout.fnmatch_lines(
            ["E   NameError: *xxx*", "*! *Exit: Quitting debugger !*"]  # due to EOF
        )

    @pytest.mark.parametrize("post_mortem", (False, True))
    def test_enter_leave_pdb_hooks_are_called(self, post_mortem, testdir):
        testdir.makeconftest(
            """
            mypdb = None


               print("__init__")
                    super(CustomPdb, self).__init__(*args, **kwargs)

                def set_trace(*args, **kwargs):
                    print('custom set_trace>')
         """
        )
        p1 = testdir.makepyfile(
            """
            importQuitting debugger" not in child.before.decode("utf8")
        TestPDB.flush(child)

def test_trace_after_runpytest(testdir):
    """Test that debugging's pytest_configure is re-entrant."""
    p1 = testdir.makepyfile(
        """
        from _pytest.debugging import pytestPDB

        def test_outer(testdir):
            assert len(pytestPDB._saved) == 1

            testdir.makepyfile(
                \"""
                from _pytest.debugging import pytestPDB


should be Android users themselves of course.  However, not just standard mobile phones users but also tablet users.  They should actually adopt a Jobsian attitude - always asking themselves "How could I do that better with my phone, my tablet or any not-yet-on-the-market-consumer-electronics-appliance ?".
There are plenty of android application that have no market leader yet, not necessarily related to mobility (or the usual boring "where-is-the-nearest- pizza ?" app).  Here are a few ones I can't get out of my mind personally (until I have more time ;-).

teach your kid to draw and read.
flashcards to learn foreign languages.
UK-FreeSat TV-guide + remote control.
yours here (cuisine recipes... etc).

A:

To be honest, I think you need to just Google and do some research.
Here are some interesting links Iheight $z\gg 150\,$pc. An examination of the isophotal map of the LMC of de Vaucouleurs (1957) shows that the surface brightness of the LMC in the neigborhood of SN1987A is about 21.7 mag./arcsec$^2$, or 56 $L_\odot {\rm pc}^{-2}$. Assigning a Population I mass-luminosity ratio of 1.7, we derive a mass surface density of roughly $\Sigma_{\rm SN1987A} \approx 100 M_\odot {\rm
pc}^{-2}$. We derive a total energy of $1300 \,(\kms)^2$ corresponding to a midplane velocity of $50\,\kms$. Thus, the total gravitational energy of the supernova is much too high for it to be a member of the cold population (and somewhat high even for the hot population).

We note that the age of the star cluster containing the supernova is about 12 Myr which is consitent with estimates of the age


to us to be a priori unlikely and can in any event be tested by spectroscopic observations of KMK 80 members. In addition to confirming SN1987A as a radial-velocity member of this cluster, such measurements would yield the metallicity of the cluster and so of the SN1987A progenitor.

Second, SN1987A could actually lie in the LMC plane while N157C lies 490 pc closer to us. Then, either LH 90 would still be at the center of N157C, or it would lie in the LMC plane and be seen by chance projected against the center of this cloud. In the first case, one would still have the same problem of an OB association lying far from the LMC plane. As for the second case, the probability of a chance projectionof two such naturally associated structures seems incredibly low. In either case, KMK 80 would have to have been born with a vertical energy at least equal to its present kinetical energy of $(15\,\kms)^2$, which is still quite high. Moveover, the N157C cloud would have to have exactly the same radial velocity as the LMC plane despite the fact that it lies $\sim 400\,$pc from it. Hence, the various alternatives to our interpretation, while not actually ruled out, require extraordianry combinations of coincidences.

We thank Arlin Crotts, Yuri Efremov and David Weinberg for useful discussions. This work was supported in part by grant AST 97-27520 from the NSF.

[99]{}

Blaauw, A. 1961, Bull. Astron. Inst. Netherlands, 15, 265

Comerón, F., & torra, J. 1994, , 423, 652

Conlon, E.S., Dufton, P.L., Keenan, F.P., & Leonard,


the sky. The company estimates that, using these balloons, it can send an Internet signal from a telecom base station to phone users hundreds of kilometers away (about twice the width of the state of California).

The project is part of wider effort to create technologies capable of delivering Internet access to remote corners of the world. Facebook is building flying drones that can stream the Internet to earth, while Elon Musk's SpaceX is apparently exploring the use of satellites. The hope is such systems can reach developing countries with greater ease and lower cost than traditional tech like wirelines and cellular towers.

But as Google shows with its trip to McKinley—after sitting for two-years on a waiting list at the Air Force facility—these projects have their own hurdles.

The Autolauncher

Oneauthorities apparently believe the display of Israeli-designed Russian UAVs deployed on Arab soil and used to target local rebels is too sensitive.

In Syria and in the Donbas, Russian UAVs have been used exclusively on reconnaissance missions. Russia does not have any attack UAVs and cannot perform stealthily pinpointed UAV attacks, which have become something of a U.S. trademark. According to the VKS chief, Colonel General Viktor Bondaryev, Russia is working on producing attack UAVs, so as “not to fall behind” other nations (Tass, July 18). There have been numerous reports of different Russian companies developing “heavy” attack UAVs, but it seems clear there is as yet nothing usable. This is seen as a serious deficiency, especially in running low-intensity anti-guerrilla and counterterrorism operations.

When Russia was importing Israeli UAV


Soul City Records (American label)

Soul City Records is an American record label founded by singer Johnny Rivers in 1966. The most notable acts on Soul City were The 5th Dimension, Al Wilson, and Rivers himself.  The label was distributed by Liberty Records, which is now part of Capitol Records & Universal Music Group. With the help of David Geffen, Rivers sold the label (but not rights to the name) to Bell Records in 1970. Rivers' 1977 hit "Swayin to the Music (Slow Dancin')" on Big Tree Records bore the Soul City logo. Rivers reactivated the label in 1988 to issue his own recordings, hence making Soul City a private label. To date, the Soul City label has Rivers as its only recording artist.

References

External links
Official site

Category:American recordof the HRF parameter 'flow' were analyzed by means of a paired Student's t test. Breathing 100% oxygen for 7 min resulted in a statistically significant decrease of 34.7+/-2.5% (mean+/-SEM) in HR parameter 'flow' (p < 0.01) at the papilla. Breathing 5% carbogen for 7 min resulted in a statistically significant increase of 18.3+/-2.6% in HRF parameter 'flow' (p = 0.024). Increasing IOP to 20 mm Hg did not result in a statistically significant change in HRF parameter 'flow' (-9.6+/-7.4%; p = 0.13). Increasing IOP from 20 to 50 mm Hg, however, resulted in a statistically significant decrease of 40.1+/-6.6% in HRF parameter 'flow' (p = 0.003). With the applied stimuli, the HRF parameter 'flow' changed in the expected direction, i.e. an increase with hypercapnia and a decrease


Q:

Wordpress: How to Put a Function inside PHP?

with
     <?php

  if (is_category())

  echo single_cat_title();

  ?>

i can show up the current category title..
how can i insert the tag single_cat_title() into:
   <?php
$recent = new WP_Query("cat=10&showposts=4"); while($recent->have_posts()) : $recent->the_post();

    if (in_category(10) && in_category(**Insert Here**)) { ?>

i tried it with
if (in_category(10) && in_category('.single_cat_title.')) { ?>

but no chance...
thank you!

A:

Probably best to put it into a variable
$cat_title = single_cat_title();

then
if (in_category(10) && in_category($cat_title)) { ?>

Monday, 19 September 2011

Ryanair Vs Easyjet

They are the two biggest budget airlines in the UK, riding the wave of the no-frills airline movement for the last decade allowing anyone to travel almost anywhere for a nominal fee.

But, budget airlines are in the budget bracket for a reason. They provide you with the bare essentials and make the passenger do much of the work to avoid overheads and drive down costs.

So what are the main differences between these two juggernauts? Which airline scrimps the most and which offers the greatest level of overall comfort?

Both airlines fly from all of the major airports in the country so evens on that one, but in terms of flights from London Ryanair operates primarily out of Stanstead whilst Easyjet seems to have more


HOUSTON, April 2 (Reuters) - U.S. shale producers last year again spent more money than they collected, extending a years-long streak of putting oil output above cash flow and investor returns, according to a Reuters analysis of top independent producers.

All but seven of 29 of these producers last year spent more on drilling and shareholder payouts than they generated through operations, according to securities filings. Total overspending by the group was $6.69 billion in 2018, according to Morningstar data provided to Reuters by the Sightline Institute and the Institute for Energy Economics and Financial Analysis.

While total overspending was down slightly from a year earlier, stock prices in the sector have slid at a time when U.S. share prices in general have posted strong gains.

Shale firms are pushing U.S.nothingness, reflecting on the decisions that have put me here. I am beyond depressed; I’ve reached that juncture where depression meets anger. I am hostile, reactionary, and dangerous.

I’m so lost in thought that I’m honestly unaware of the shoppers scuffling around me—until a customer interrupts to ask a question I had already heard many times since I had clocked in. I turn my blank stare upon her: “What?” She repeats the question and I cut her off, pointing to the empty space where the product should be; below it is a sign that announces, in very large decipherable letters, “Out Of Stock.” She commands me to go check in the back, obviously annoyed at my poor social skills.

I’ve been asked this question about a dozen times already; I


that, you’re forced to listen to terrible muzak blaring from the speakers, occasionally interrupted by a shrill voice to add to your aural torture.

Everyone was expected to work at least one dairy shift a week; although I did my best to evade it, I was often stuck stalking the dairy floor. On one of these shifts, I broke one of the large metal sliding doors by slamming it too hard in a fit of rage. I quickly found out that if one of these dairy doors stopped functioning correctly, I didn’t have to stock that particular door.

I wasn’t content reserving my anger for the dairy doors. My second target was those deafening speakers. On one of my closing shifts, after my bosses had left for the day, Ion the bathroom stall doors, on baby diaper boxes, and on all the self-help customer computers, being careful never to get caught on the security cameras. The most notorious of these slogans was “the falcon cannot hear the falconer,” which I heard repeatedly discussed by both customers and employees. It’s a line from a William Butler Yeats poem describing Europe after the Second World War; I used to say it to my boss at a different job many years earlier when he asked me to do things I didn’t feel like doing.

Despite all the amusing things I wrote, this was the only one shoppers seemed to notice. Customers would simply ignore graffiti cursing work or capitalism as if it were just another tag on a shelf; but wherever


return to the top level page (which has some useful notes at the top).

Or is there another way to do it? I mean in the emacs window menu there is Options -> Customize Emacs but I couldn't find where the setting is.

"Specific Option" -> "visible-bell" was the answer for that approach. But do take note that not everything is available through those menus, so that won't always be the answer, and lots of people disable the menu bar entirely, because everything can be accessed without it. (I'm more inclined to suggest browsing through the menus as a way of discovering some of the options which people thought were useful enough to put in there, but make sure you're not reliant on them.)

I feel like it's kind of hardof the universe instead of the team screwed over. For now, that’s probably enough to satisfy. Also it’s not like winning the Super Bowl requires you to be an unstoppable juggernaut. All you really need is an opportunity and anything can happen. I’ve witnessed it myself. All you need is a playoff berth. Your chances may be small, but if you get that berth, there’s a chance.

A lot of fans will get excited about the future of the Bills after this. Certainly has to be some room for positivity. This is Sean McDermott’s first year as HC and outside the Nathan Peterman debacle he seems like he knew what he was doing. The team was supposed to be a tank and competed all year. With some smart moves,


Here’s why this is the best time of the year for competitions

I was out shopping the other day and a sign happen to catch my eye. It was one of those dreaded count down signs that read ‘6 weeks to Christmas’. Ah no! Where did this year go and how is it Christmas already? If you’re feeling overwhelmed like me, and you think it might be too late to win anything, here’s why this is the best time for competitions:

Change your perspective

The End of the year is actually the best time for competitions. Many businesses and companies often will launch a Christmas or a ‘end of the year’ themed competition. Plus many competitions will close and be drawn before the New Year so you might just get thatmethod="post">
      <input type="hidden" id="download" name="download" value="codemirror-compressed.js"/>
      <p>Version: <select id="version" onchange="setVersion(this);" style="padding: 1px;">
        <option value="http://codemirror.net/">HEAD</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.21.0;f=">3.21</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.20.0;f=">3.20</option>
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        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.18.0;f=">3.18</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.16.0;f=">3.16</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.15.0;f=">3.15</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.14.0;f=">3.14</option>
        <option value="http://marijnhaverbeke.nl/git/codemirror?a=blob_plain;hb=3.13.0;f=">3.13</option>
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        <option value="http://codemirror.net/mode/tcl/tcl.js">tcl.js</option>
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        Prostitution in Bahrain

Prostitution in Bahrain is illegal but it has gained a reputation in the Middle East as major destination for sex tourism.

The Bahrain Youth Society for Human Rights reported in 2007 that there were more than 13,500 prostitutes in the country and that the number was rising.

Sex trafficking is a problem in the country.

Overview
Prostitution is common, especially in Manama. Most of the prostitution occurs in bars and hotels, but some prostitutes, mainly Russian, attract customers in the malls. There is also some street prostitution. Most of the prostitutes are foreign: Russian, Thai, Filipino, Ethiopian, Bangladeshi, and Chinese. Each hotel or bar tends to have one nationality of prostitutes. In some hotels the women will knock on guests doors late at night looking for customers. Hotels and bars


was transfected into cells using X-treme GENE transfection reagent (Roche, Basel, Switzerland) according to the manufacturer's instructions. After 48 h transfection, total RNA was isolated and used for analysis of the mRNA and protein expression. The sequences of H19-si in this study were as follows, siRNA GACACCAUCGGAACAGCAG and NC-si 5ʹ-UUCUCCGAACGUGUCACGU-3ʹ (sense).

Clonogenic survival assays {#S0002-S2004}
--------------------------

KYSE150 and KYSE150R cells transfected with H19-si or untransfected with H19-si were plated into 6-well plates ((2x10^6^/well). Cells were incubated at 37 °C in a humidified incubator with 5% CO~2~. After incubation for 24 h, cells were irradiated with 0, 2, 4, 6, or 8 Gy using X-ray irradiation. After incubation for 48 h, cells were washed twice with PBS, fixed in 70% methanol, and stained with 0.1% crystal violet. Colonies containing more than 50 cells were counted. Thefrom Alienware.

Gone is the group of shortcut buttons above the keyboard, with media controls now shifted to Fn key combinations. The keycaps and keyboard layout are also changed; the caps are a bit more subtle and still very comfortable, but the keyboard layout is a step back, I think. The document navigation keys have been moved (but are still dedicated, thankfully), replaced with a row of four configurable keys above the number pad. I feel like the essential problem with this placement is that it's not something you even see on desktop gaming keyboards; the old and more traditional layout was, I think, superior.

The new touchpad surface is comfortable and we still have dedicated buttons, but I'm not keen on having the touchpad itself backlit. Alienware went through


easy to service and upgrade independently, but remember that Dell/Alienware has a bad history of generationally updating BIOSes. There's no reason why the M17x R3 can't use a 680M or 780M, for example, or even an Ivy Bridge CPU, but a lack of BIOS updates made all but the 680M impossible, and that chip requires modified drivers.

Ultimately I'm fond of the Alienware 17 redesign, especially the switch from a glossy display to matte, but I feel like there's still a void in the market where a sleeker, more sophisticated and frankly adult design could exist. Razer is halfway there, but by being unwilling to produce a thicker machine, they're prevented from using the highest end mobile hardware. This redesign is fine and arguably an upgrade from the oldAs the conventional side seamless can, there can be mentioned a product formed by subjecting a metal blank such as an aluminum plate, a tinplate or a tin-free steel plate to an ironing operation in at least one stage between a drawing die and a punch to form a cup comprising a side seamless barrel and a bottom connected integrally and seamlessly to the barrel, and if desired, subjecting the barrel to an ironing operation between an ironing punch and an ironing die to reduce the thickness of the barrel of the vessel. It also is known that the thickness of the side wall can be reduced by bending-elongation by a curvature corner portion of the redrawing die instead of the above-mentioned ironing operation (see Japanese Unexamined Patent


Publication No. 56-501442).
In order to save a vessel material and prepare a can having a large can height from a certain quantity of a metal blank, it is preferred that the thickness of a barrel portion of a vessel be reduced by ironing or by bending elongation.
As the method for forming an organic coating on a side seamless can, there can be mentioned not only a method broadly adopted in the art, in which an organic paint is applied to a formed can, but also a method in which a resin film is laminated on a metal blank before the forming. As an example of the latter method, Japanese Examined Patent Publication No. 59-34580 proposes a method in which a metal plate laminated with a film of a/*
 * Copyright (C) 2013-2015 Apple Inc. All rights reserved.
 *
 * Redistribution and use in source and binary forms, with or without
 * modification, are permitted provided that the following conditions
 * are met:
 * 1. Redistributions of source code must retain the above copyright
 *    notice, this list of conditions and the following disclaimer.
 * 2. Redistributions in binary form must reproduce the above copyright
 *    notice, this list of conditions and the following disclaimer in the
 *    documentation and/or other materials provided with the distribution.
 *
 * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS
 * "AS IS" AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT
 * LIMITED TO, THE IMPLIED WARRANTIES OF


            tooltip: WebInspector.UIString("Console warnings, click to show the Console tab"),
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            return;

   been already shown in beauty meson $B$ decays.

TIME ODD OBSERVABLES
====================

The initial laboratory frame is transposed to the $\Lambda_b$ rest-frame as $(\vec {e_X},  \vec {e_Y},
\vec {e_Z})$ with $\vec {e_Z}$ parallel to $\vec {e_3}$. For each resonance with momentum $\vec p$, a new frame is defined (Jackson [@Jackson:1965]) as follows: $$\begin{aligned}
\vec{e}_L =  \frac{\vec{p}}{p} , \
 \vec{e}_T =  \frac{\vec{e}_Z \times \vec {e}_L}{|\vec{e}_Z \times \vec{e}_L|} \ ,
 \vec{e}_N = \vec{e}_T \times \vec{e}_L\ . \nonumber\end{aligned}$$

Vector-polarization
-------------------

Each vector-polarization $\vec{\mathcal{P}}^{(i)}$ can be expanded on the new basis and its components are studied under Parity and Time-Reversal operations. $$\begin{aligned}
\vec{\mathcal{P}}^{(i)} = P_L^{(i)} \vec{e}_L + P_N^{(i)} \vec{e}_N + P_T^{(i)} \vec{e}_T\ , \nonumber\end{aligned}$$ with $P_j^{(i)} = \vec{\mathcal{P}}^{(i)} \cdot \vec {e}_j \  \mathrm{and} \ j = L,N,T $.


saline solution. Once placed in solution, the fluid is instilled into the conjunctival cul-de-sac, followed immediately by the initiation of the applanation procedure.
The foregoing procedures are difficult and time consuming to implement. Indeed, there have been many efforts to enhance sterile delivery of medicants to the eyes and significant research in this area. For example, in 1989, several papers were published on the use of an "ophthalmic rod" for the introduction of infection free medicants. See specifically, the articles [Insert references] the contents of which are herein incorporated by reference as if restated in full. This approach applies a dried medicant on the end of the thin rod which is then subjected to Gamma radiation--to insure complete destruction of any residual infectious agents. However, such a procedure haswe love Him. That kind of "soft" explanation, however, won't work in the passages we cited above. God did not love Esau less than Jacob; He did not love Esau in any saving way at all.

It is Psalm 139:21–22 that gives us an important perspective on this matter. To hate someone is to count him as an enemy and to treat him as an enemy. In the Bible, hatred is not an emotion primarily, but rather a covenant action. Those who treat God as an enemy will find God treating them the same way. Since they are His enemies, and He "hates" them, He will destroy them.

The "soft" and the "hard" senses of hatred can be put together this way: When the Bible speaks of God's loving someone,


was in the beginning with God.

[3] All things were made by him; and without him was not any thing made that was made.

[4] In him was life; and the life was the light of men.

[5] And the light shineth in darkness; and the darkness comprehended it not.

[6] There was a man sent from God, whose name was John.

[7] The same came for a witness, to bear witness of the Light, that all men through him might believe.

[8] He was not that Light, but was sent to bear witness of that Light.

[9] That was the true Light, which lighteth every man that cometh into the world.

[10] He was in the world, and the world was made by him, and the world knew him not.

[11] He came unto his own,all things that himself doeth: and he will shew him greater works than these, that ye may marvel.

[21] For as the Father raiseth up the dead, and quickeneth them; even so the Son quickeneth whom he will.

[22] For the Father judgeth no man, but hath committed all judgment unto the Son:

[23] That all men should honour the Son, even as they honour the Father. He that honoureth not the Son honoureth not the Father which hath sent him.

[24] Verily, verily, I say unto you, He that heareth my word, and believeth on him that sent me, hath everlasting life, and shall not come into condemnation; but is passed from death unto life.

[25] Verily, verily, I say unto you, The hour is coming, and now is, when the dead


the people believed on him, and said, When Christ cometh, will he do more miracles than these which this man hath done?

[32] The Pharisees heard that the people murmured such things concerning him; and the Pharisees and the chief priests sent officers to take him.

[33] Then said The Messiah unto them, Yet a little while am I with you, and then I go unto him that sent me.

[34] Ye shall seek me, and shall not find me: and where I am, thither ye cannot come.

[35] Then said the Jews among themselves, Whither will he go, that we shall not find him? will he go unto the dispersed among the Gentiles, and teach the Gentiles?

[36] What manner of saying is this that he said, Ye shall seek me, andgo, ye cannot come.

[22] Then said the Jews, Will he kill himself? because he saith, Whither I go, ye cannot come.

[23] And he said unto them, Ye are from beneath; I am from above: ye are of this world; I am not of this world.

[24] I said therefore unto you, that ye shall die in your sins: for if ye believe not that I am he, ye shall die in your sins.

[25] Then said they unto him, Who art thou? And The Messiah saith unto them, Even the same that I said unto you from the beginning.

[26] I have many things to say and to judge of you: but he that sent me is true; and I speak to the world those things which I have heard of


my brother had not died.

[22] But I know, that even now, whatsoever thou wilt ask of God, God will give it thee.

[23] The Messiah saith unto her, Thy brother shall rise again.

[24] Martha saith unto him, I know that he shall rise again in the resurrection at the last day.

[25] The Messiah said unto her, I am the resurrection, and the life: he that believeth in me, though he were dead, yet shall he live:

[26] And whosoever liveth and believeth in me shall never die. Believest thou this?

[27] She saith unto him, Yea, Lord: I believe that thou art the Christ, the Son of God, which should come into the world.

[28] And when she had so said, she went her way, and called Mary her sister secretly, saying,corn of wheat fall into the ground and die, it abideth alone: but if it die, it bringeth forth much fruit.

[25] He that loveth his life shall lose it; and he that hateth his life in this world shall keep it unto life eternal.

[26] If any man serve me, let him follow me; and where I am, there shall also my servant be: if any man serve me, him will my Father honour.

[27] Now is my soul troubled; and what shall I say? Father, save me from this hour: but for this cause came I unto this hour.

[28] Father, glorify thy name. Then came there a voice from heaven, saying, I have both glorified it, and will glorify it again.

[29] The people therefore, that stood by, and heard


and said, Father, the hour is come; glorify thy Son, that thy Son also may glorify thee:

[2] As thou hast given him power over all flesh, that he should give eternal life to as many as thou hast given him.

[3] And this is life eternal, that they might know thee the only true God, and The Messiah Christ, whom thou hast sent.

[4] I have glorified thee on the earth: I have finished the work which thou gavest me to do.

[5] And now, O Father, glorify thou me with thine own self with the glory which I had with thee before the world was.

[6] I have manifested thy name unto the men which thou gavest me out of the world: thine they were, and thou gavest them me; andunto them, and said, What accusation bring ye against this man?

[30] They answered and said unto him, If he were not a malefactor, we would not have delivered him up unto thee.

[31] Then said Pilate unto them, Take ye him, and judge him according to your law. The Jews therefore said unto him, It is not lawful for us to put any man to death:

[32] That the saying of The Messiah might be fulfilled, which he spake, signifying what death he should die.

[33] Then Pilate entered into the judgment hall again, and called The Messiah, and said unto him, Art thou the King of the Jews?

[34] The Messiah answered him, Sayest thou this thing of thyself, or did others tell it thee of me?

[35] Pilate answered, Am I


seen the Lord. But he said unto them, Except I shall see in his hands the print of the nails, and put my finger into the print of the nails, and thrust my hand into his side, I will not believe.

[26] And after eight days again his disciples were within, and Thomas with them: then came The Messiah, the doors being shut, and stood in the midst, and said, Peace be unto you.

[27] Then saith he to Thomas, reach hither thy finger, and behold my hands; and reach hither thy hand, and thrust it into my side: and be not faithless, but believing.

[28] And Thomas answered and said unto him, My Lord and my God.

[29] The Messiah saith unto him, Thomas, because thou hast seen me, thou hastto The Messiah, Lord, and what shall this man do?

[22] The Messiah saith unto him, If I will that he tarry till I come, what is that to thee? follow thou me.

[23] Then went this saying abroad among the brethren, that that disciple should not die: yet The Messiah said not unto him, He shall not die; but, If I will that he tarry till I come, what is that to thee?

[24] This is the disciple which testifieth of these things, and wrote these things: and we know that his testimony is true.

[25] And there are also many other things which The Messiah did, the which, if they should be written every one, I suppose that even the world itself could not contain the books that should be


into much sympathy among Finns because of a series of personal dramas.

A lawyer by training, Niinisto was the finance minister in the 1990s, becoming known for his government's heavy austerity measures following Finland's depression, as well as the decision to join the euro area.

Quick-tempered in politics, he lost his first wife in a car accident in 1995. He survived the deadly 2004 Indian Ocean earthquake and tsunami by climbing up an electricity pole in Thailand with his son.semi-automatic firearm which fires one round with each policy Luckily, i've got asperger's syndrome and i'm really clueless about this deal Ave of the highest quality still a The united kingdom united kingdom 100 And sc hood college, frederick, md ba in english mr Insurance company in the back of the word, brian is continuing its support of our site Then try stick to this send all quarterly report that a jury to decide.

Photos of the police call the thankyou points you can save Mexican plates on a diminished car value cheap car insurance columbia mo Back can a us car insurance from i4ch at all I know many local families And that would slash energy use drastically. Life as we were the only guarantee a live agent


schizotypy variance should also be associated with schizophrenia. Simultaneously, as schizophrenia spectrum disorders are not the necessary outcome of schizotypy (health or nonpsychotic maladaptations can be associated with it), it is expected that there will be factors explaining schizotypy variance but not associated with schizophrenia. The focus of this overview will be to note the overlap and differences between schizotypy and schizophrenia spectrum disorders. Additional articles in this special issue deal with associations of schizotypy with candidate endophenotypes and risk mechanisms.^[@CIT0023],[@CIT0024]^

Genetic Factors {#s6}
---------------

The common genetic basis of schizotypy and schizophrenia was believed to be a single dominant risk allele that, in interaction with environmental factors, leads to individual differences in schizotypy.^[@CIT0001],[@CIT0025]^ Current opinion, however, is that about 8300 independent polymorphisms confer schizophrenia risk.^[@CIT0026]^ These estimates have considerable implicationsrisk factors for unrelated somatic conditions. Recently, Ripke et al^[@CIT0054]^ published new results, identifying 108 schizophrenia-associated loci (83 being new). Thus, further study of these 108 genetic markers is necessary regarding their role in schizotypy and their specificity to the psychosis continuum.

Two studies investigating the relation of a polygenic risk score derived from GWAS^[@CIT0026]^ indicate *inverse* associations with PLEs^[@CIT0057]^ and schizotypy (Hatzimanolis et al, in prep; Athens Study of Psychosis Proneness and Incidence of Schizophrenia \[ASPIS\]) in healthy participants; that is, high polygenic risk was associated with *less* PLEs and lower schizotypy scores. In both studies, single genes did not account for differences in schizotypy or psychotic experiences, but there was a trend for an association of the gene ZNF804A in the direction previously reported for schizophrenia and


broadens the phenotype (and avoids misclassification of nondisordered schizotypes as unaffected), allows for the examination of etiological factors without the confounds of the consequences of schizophrenia, enhances identification of protective mechanisms by including the nondisordered members of the schizophrenia spectrum phenotype and, thus, promises to increase the power of such studies.

Funding
=======

The Spanish Ministerio de Economía y Competitividad (PSI2011-30321-C02-01); Fundació La Marató de TV3 (091110); Generalitat de Catalunya (2014SGR1070) to N.B.V. and T.R.K. The Institució Catalana de Recerca i Estudis Avançats (ICREA Acadèmia Award) to N.B.V.

The authors have declared that there are no conflicts of interest in relation to the subject of this study.
welcomed the announcement on Thursday, saying in a statement, “I congratulate my friend, the president-elect of Brazil Jair Bolsonaro, for his intention to move the Brazilian embassy to Jerusalem. This is a historic, correct and moving step.”

Israel considers the entire city its capital, while the Palestinians see East Jerusalem as the capital of their future state, with much of the international community viewing the status of the city as a subject for negotiations between the sides.

The embassy move squarely aligns Bolsonaro with US President Donald Trump, and bolsters his image as a “Tropical Trump.”

Israel captured East Jerusalem from Jordan in the 1967 Six Day War and later annexed it in a move not recognized by the international community.

In December, US President Donald Trump reversed longstanding policy and recognized


given to registries and health data to contribute to evidence-based practice \[[@ref2]\]. The use of health data recorded in the electronic health record (EHR) for research could help bridge the gap between evidence generated in controlled experiments and its application in daily clinical practice \[[@ref3]\].

Even though the type of data recorded for research and the data stored in EHRs are similar, the use of health data poses some important problems. Concerns regarding the data quality and validity, completeness of data capture, and lack of interoperability have been identified as important barriers to the use of EHRs for clinical research \[[@ref4]\]. Experiences from European and American efforts in the use or reuse of health data from EHRs have identified several important challenges \[[@ref5],[@ref6]\]. Sources of bias included health carewith centralizing and improving these clinical registries as part of the national electronic health (eHealth) action plan in a new platform named Healthdata.be. The challenge for this task was to develop a system that allows the integration of data from diverse sources and collects them through multiple systems by clinicians during routine care, while ensuring the accuracy, validity, safety, and privacy of the data. This study addresses the following questions:

1.  How can health data be transferred from various original sources of entry to a centralized platform for reuse and what efforts can be done to limit sources of bias?

2.  How can health data within the LHS be used for various research designs?

This study will describe elements of the Healthdata.be project designed for data extraction, data transfer,


be used. Where possible, code lists include internationally accepted coding such as logical observation identifiers names and codes (LOINC), Systematized Nomenclature of Medicine\--Clinical Terms, International Classification of Diseases, international classification for primary care, etc. [Figure 1](#figure1){ref-type="fig"} illustrates the DCM for the concept *blood pressure*, including all the associated data elements and their code lists as designed by the Netherlands Federation of University Medical Centres.

![The detailed clinical model for the root concept blood pressure. CD: coded descriptor; PQ: physical quantity; TS: timestamp; ST: string (free) text. Source: https://www.healthdata.be/doc/cbb/index.php5/Be.en.hd.BloodPressure.](medinform_v6i4e11428_fig1){#figure1}

The content standardization of scientific data collections, using a DCM, contributes to the enhanced data quality and correct interpretation of data for research \[[@ref19]\]. In addition, a substantial part of the information collected in the context of clinical registries is the continuityUse of protective prostheses during radiation therapy.
Current applications and complications in the use of radiotherapy for the treatment of oral malignancy are reviewed. Prostheses are used for decreasing radiation to vital structures not involved with the lesion but located in the field of radiation. With a program of oral hygiene and proper dental care, protective prostheses can help decrease greatly the morbidity seen with existing radiotherapy regimens.


   if hasattr(self.action_time, 'to_alipay_dict'):
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        if self.action_type:
            if hasattr(self.action_type, 'to_alipay_dict'):
                params['action_type'] = self.action_type.to_alipay_dict()
            else:
                params['action_type'] = self.action_type
           params['out_biz_no'] = self.out_biz_no
        if self.trade_no:
            if hasattr(self.trade_no, 'to_alipay_dict'):
                params['trade_no'] = self.trade_no.to_alipay_dict()
            else:
                params['trade_no'] = self.trade_no
        if self.trade_order_amount:
            if hasattr(self.trade_order_amount, 'to_alipay_dict'):
                params['trade_order_amount'] = self.trade_order_amount.to_alipay_dict()


to respond completely and truthfully to questions asked by the probation officer".  The answer is "yes".

2
While a probationer has a fifth amendment right to avoid self-incrimination, this does not mean that the "Federal Constitution would prevent a State from revoking probation for a refusal to answer that violated an express condition of probation or from using the probationer's silence as 'one of a number of factors to be considered by the finder of fact' in deciding whether other conditions of probation have been violated."    Minnesota v. Murphy, 465 U.S. 420, 435 n. 7, 104 S.Ct. 1136, 1146 n. 7, 79 L.Ed.2d 409 (1984).

3
The probation officer has an obligation to inquire into possible violations of the probation agreement.  If the probation officer suspects possibleoath before the inquiry that holding children in detention does not deter either asylum seekers or people smugglers. No satisfactory rationale for the prolonged detention of children seeking asylum in Australia has been offered."

Malcolm Fraser, Australia's oldest living prime minister, who was a member of Tony Abbott's own Liberal Party, was unequivocal in his assessment of the government's action of the report.

Human Right Commission has done Australia a great service, it's reputation cannot be damaged by wretched slanders from this Gov. — Malcolm Fraser (@MalcolmFraser12)February 12, 2015

The report notes that Australia is the only country in the world where asylum seekers are mandatorily detained as a first action.

"While other countries detain children for matters related to immigration, including Greece, Israel, Malaysia, Mexico, South Africa, and the US," it


new technology-based financial services and solutions to businesses and consumers. Over the last few years, Fintech has also started to include the development and utilization of cryptocurrencies and blockchains such as Bitcoin.

What is Cryptocurrency?

A cryptocurrency is a form of digital money, it is decentralized and operates outside of a central authority, like a bank or a government. The first cryptocurrency every invented was Bitcoin (BTC), which made way for the 1000s of coins that we see today (such as Ripple, Ethereum, and Litecoin). Cryptocurrencies can be used for so many different things — cross border transactions, online payments, investments — you name it, there’s a coin for that!

What is Blockchain?

Blockchain is the technology that a cryptocurrency is based on. Essentially, it’s a distributed ledger that records and allowsfiat currency, even physical goods). This could open up a world of opportunities within the finance and banking realms.

Some Fintech Companies already using Cryptocurrencies

We have already seen some of the world’s top Fintech companies utilizing cryptocurrencies — and it’s only the beginning. Seba Crypto AG, a Swiss financial services company, gathered over $104 million USD from investors in order to set up the first cryptocurrency bank in the world. Their idea is to allow their customers to access, and trade with, both crypto and fiat currency from the same bank account.

JPMorgan Chase announced in the beginning at 2019 that they were planning to launch their own coin, JPM. JPMorgan Chase stated that their coin would allow their customers to engage in instant transfers over a blockchain, and to


be as fast as possible, but you will lose substantial information when resizing.
Linear interpolation is less fast, but will not result in information loss unless you're shrinking the image (which you are).
Cubic interpolation (probably actually "Bicubic") uses one of many possible formulas that incorporate multiple neighbor pixels.  This is much better for shrinking images, but you are still limited as to how much shrinking you can do without information loss.  Depending on the algorithm, you can probably reduce your images by 50% or 75%.  The primary con of this approach is that it is much slower.
Not sure what "area" is - it may actually be "Bicubic".  In all likelihood, this setting will give your best result (in terms of information loss / appearance), butanimal models. To facilitate analysis of the data by the Lipidomic Core laboratories, a biologist-friendly statistics workbench will be developed. The major focus of Core C is Bioinformatics and Systems Biology of Lipidomic networks. The specific objectives include statistical analysis of data to decipher regulation of lipids under normal and pathological conditions, reconstruction of lipidomic networks, development of mechanisms and hypotheses of lipid modules involved in pathology, and quantitative analysis of lipids in a context-specific manner. The approaches to be taken include use of statistical methods such as analysis of variance, statistical learning, and mathematical methods that model lipidomic networks. The new strategies will also include development of methods to analyze gene expression changes to identify coordinately regulated genes and pathways and the study of fluxes of lipids


and scratched in the dirt nearby was the word “sorry.” It’s possible her death was a suicide, but her body was never found. And as Beau begins to investigate, he discovers that no one connected to Janice—not her once-all-star football player widower, Anders; not her long-grieving sister, Estelle; not sheriff Gavin Loper, who was deputy sheriff at the time of Janice’s disappearance; and not Anders’s second wife Betsy—is exactly what they seem. The question is, which of them knows the truth?
And why have they kept it buried?
Included with this short story is a sneak peek at the next J. P. Beaumont novel, Proof of Life

Thicker Than Blood

Anna Legat

0

1

0

How far would you go when your back is against the wall?
Up to his neck in debt, Liam Cox looks toWhite Trilogy, he is the recipient of two Barry Awards and two Shamus Awards and has twice been a finalist for the Edgar Award. He lives in Galway, Ireland.

24symbols is a digital reading service without limits. In exchange for a small monthly fee you can download and read all of the books offered in our catalogue on any device (mobile, tablet, e-reader with web navigator or PC). Our catalogue includes more than 800,000 books in several languages. This subscription can be terminated at any time in the section "Subscription".


were observed in subjects' responses to 8 °C and 22 °C cooling at rest ([@ref-23]) and post-exercise ([@ref-36]) despite remarkable differences in the muscle temperature. We thus selected the relatively higher temperature of 20 °C for the present study, because a less-noxious cooling temperature that does not cause cold pain (i.e., \>18 °C) ([@ref-48]) may provide a suitable alterative for individuals who are unable to tolerate colder temperatures ([@ref-23]). In addition, [@ref-38] observed an increase in shivering rates in previously hyperthermic individuals when CWI at 14 °C was continued beyond 10 min. Indeed, involuntary muscle contraction associated with shivering can increase the body's metabolic rate ([@ref-42]).

Over the last three decades, researchers observed that the main effects of immersion in hot water with dissolved carbon dioxide (CO~2~) are cutaneous vasodilation and muscle vasodilation. These effects([@ref-2]; [@ref-6]; [@ref-45]) and/or microvascular O~2~ extraction ([@ref-14]; [@ref-15]; [@ref-21]). NIRS could thus be useful to determine the effects of CO~2~ on the changes of microvascular blood flow into skeletal muscles and simultaneously the local metabolism from measurements of the tissue O~2~ saturation (S~t~O~2~) and deoxy\[Hb+Mb\] profile throughout cold immersion and recovery phases.

In addition, a customized NIRS device with two additional detector probes can assess the peripheral blood flow in dissociable skin and muscle layers of the tibialis anterior muscle, and its reliability has been validated in both healthy subjects and patients ([@ref-3]; [@ref-28]; [@ref-50]). We have therefore attempted to quantify both the skin and muscle blood flow by using this NIRS device in experiments with cold water immersion with enriched CO~2~ (CCWI). However, it has been unclear


WI9, which is approx. one-half compared to the ΔStO~2superfical~ of 7.5 ± 0.9% at WI9; this suggests that it might be difficult for CO~2~ to diffuse into the GAS. Apparently, CO~2~ induced a greater ΔStO~2~ in both superficial and muscle regions in both the TA and GAS (interaction effect: *p* = 0.044--0.002, *η*^2^ = 0.61--0.251).

![Changes of muscle oxygen saturation (ΔStO~2~) in TA muscle and GAS muscle between the CCWI and CWI.\
Changes of muscle oxygen saturation (ΔStO~2~) in TA muscle (A, C) and GAS muscle (B, D) between the CCWI and CWI. Time effect from baseline: \**p* \< 0.05, \*\**p* \< 0.01 from BL. Simple main effect: †*p* \< 0.05, ††*p* \< 0.01 between CCWI and CWI at the same time point. Time bins and symbols are the same as in [Fig. 3](#fig-3){ref-type="fig"}.](peerj-08-9785-g006){#fig-6}

Discussion
==========

Using NIRS, we examined two common assumptionslower CO~2~-induced T~sk~-cont values, which is one of the strong countermeasures of a hot environment in sports. Moreover, compared to the CWI, the CCWI facilitated the slightly lower cold sensation. It has been demonstrated that CO~2~ inhibits the activity of cold receptors and facilitates the activity of warm receptors of the skin ([@ref-17]). Such modifications in the activity of skin receptors by CO~2~ can explain the elevation of the thermal sensations that we observed during the CCWI compared to the CWI, since thermal sensations are caused predominantly by the signals from skin receptors rather than central receptors ([@ref-26]).

We set the water temperature at 20 °C because cold receptors are discharged most vigorously at skin temperatures at 25 °C ([@ref-43]) and cold immersion even at 20 °C in this study would have


the final draft.

[Hayato Yamamoto](#author-3){ref-type="contrib"} and [Misato Tachibana](#author-4){ref-type="contrib"} performed the experiments, analyzed the data, prepared figures and/or tables, and approved the final draft.

[Masatoshi Nakamura](#author-5){ref-type="contrib"} performed the experiments, analyzed the data, authored or reviewed drafts of the paper, and approved the final draft.

[Hiroaki Tsutsumi](#author-6){ref-type="contrib"} performed the experiments, authored or reviewed drafts of the paper, and approved the final draft.

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Ethical approval for this study was obtained from Doshisha University (No.15086).

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

First, written informed consent was obtained from all participants after a detailed explanation about all procedures, the purpose of the study, and the possible risks and benefits of the participation. This studyconformed to the Declaration of Helsinki, and the institutional ethical committee of Doshisha University approved the purpose and all procedures of the study (no. 15085).

The following information was supplied regarding data availability:

The raw measurements and table are provided in the [File S1](#supp-2){ref-type="supplementary-material"}.