of cells in the S phase. Furthermore, plumbagin‑treated ESCC cells displayed a significantly greater % of apoptotic cells. Western blot analysis confirmed that plumbagin upregulated tumor protein p53 and cyclin‑dependent kinase inhibitor 1A (also known as p21), while it downregulated cyclin D1, cyclin‑dependent kinase 4, and induced myeloid leukemia cell differentiation protein Mcl‑1. Mechanistically, plumbagin inhibited STAT3 activation, and overexpression of constitutively active STAT3 reversed the plumbagin‑mediated growth suppression in ESCC cells. In vivo studies demonstrated that plumbagin delayed the growth of ESCC xenograft tumors and reduced STAT3 phosphorylation. Overall, plumbagin was demonstrated to target STAT3 signaling and to inhibit the growth of ESCC cells both in vitro and in vivo, suggesting that it may represent a potential anticancer agent for ESCC.APPLY VISA ONLINE

Vietnam visa for Canada

Canadian citizens can apply for Vietnam visa from Canada, or from any other countries
where they are staying or living in by selecting rapid visa online application.
The visa on arrival is the easiest and cheapest way for the
Canadian people getting the visa to Vietnam.

1. Vietnam and Canada relations

Canada established diplomatic relations with Vietnam in 1973, opening an Embassy in Hanoi in 1994 and a Consulate General in Ho Chi Minh City in 1997. Canada was a member of the International Commission for Supervision and Control for almost 20 years, starting in 1954, after the cessation of Vietnam’s hostilities with France.

In Vietnam, Canada is represented by the Embassy of Canada in Hanoi. Canada is also represented by a Consulate General in Ho Chi Minh City.


Q:

Binary operator ..< cannot be applied to operands 'Int' and 'Int?'

I am trying to figure out a small nuance of Swift. If I have a wrapped Int like numberOfViews is, how can I unwrap it and iterate over it in a for loop. Xcode complains that: Binary operator ..< cannot be applied to operands 'Int' and 'Int?', on the for loop line.
    let numberOfViews: Int? = dataSource?.numberOfViews(in: self)
    for i in 0..<numberOfViews ?? 0 {

    }

A:

Your issue is that ..< has higher precedence than ??, so the Range you are attempting to construct is interpreted as (0..<numberOfViews) ?? 0, which fails because numberOfViews is indeed optional. Use parentheses as follows:
for i in 0..<(numberOfViews ?? 0) {

}

A:

You can assign ais to ensure the codebase has an unified IP in order to protect the “intellectual property” of the code base or avoid legal issues, other tools exists, such as declarations of origin whereby the contrbutor states that its contributions are indeed its own. This now leads me to what I call open doors. An open doors policy is the opposite of what’s happening in the Hotel California song, where you can get in but never leave. “Open Doors” truly empowers the developers and other contributors who want to participate and bring meaningful and important contributions. Yet this principle should never bend the rules of the project so that ignores the barriers to entry. In other words: I’ve been a strong advocate of the meritocracy principle for years. I


 movntdq 16[EDI], xmm1;
          movntdq 32[EDI], xmm2;
          movntdq 48[EDI], xmm3;
          movntdq 64[EDI], xmm4;
          movntdq 80[EDI], xmm5;
          movntdq 96[EDI], xmm6;
          movntdq 112[EDI], xmm7;

          add esi, 128;
          add edi, 128;
          dec ebx;

          jnz loop_copy; //loop please
    staring at Anya. Would this info even still be good? "He didn't tell you? This is the first case in his bracket since he's moved to Manhattan. Sorry."

She shrugged, trying not to sound hurt. "I hadn't talked to him in a couple weeks. He did say he'd put in again, I guess he got approved. I can't believe he didn't call me." She glanced at her phone.

"I'm sure he will. Anyway, Gaston wanted the case, since it had all that media attention, and who's going to turn down two of the best lawyers in New York? Well, one of the best and a big named showboat."

Anastasia managed to collect herself in time to retort "That's not fair to you, Elsa, you're hardly a showboat." She giggled playfully as


her for the first time. "Well I lucked out for my lawyer." The one good thing I can say about Kuzco as a client is he never tried to make a move on me. "Well, I'm sure you already heard everything on the news. I went over to my ex-girlfriend's place, I was just checking up on her, she'd been messaging me some really scary things and I thought she was going to hurt herself. When I got there, I thought I was right. She was lying on the ground in a pool of her own blood. I tried to resuscitate her, they taught the swim team CPR back when I was in high school, I was really rusty at it, but I thought I could save her."by Marcell Ortutay

WASHINGTON -- The FBI today issued 38 subpoenas to Internet-related companies and individuals, sources report. Officials say this move will bring the anonymous Internet under compliance and regulation, effectively ending a dangerous period of anarchy in the medium's history.

[caption id="attachment_562" align="alignright" width="426"] Image Credit [/caption]

The full list of targets includes Amazon, AltaVista, AOL, eBay, GeoCities, HotMail, Lycos, Netscape, Pets.com, Yahoo!, Marc Andreessen and Tim Berners-Lee.

FBI Director Robert Mueller issued the following statement regarding today's moves:

"If the Internet remains a virtual Wild West for narcotraffickers and other criminals, that would not only threaten our country’s national security, but also the very existence of the Internet industry as a legitimate business enterprise."

Indeed, experts have speculated on the possibility of Internet applications that aid terrorists and put our national


an avenue for illegal drug trade, because it allows anyone, anywhere to post anything they want. "If we are to win the War on Drugs," says DEA chief Thomas M. Harrigan, "this has to change. Drug dealers are turning the Internet into a thieves' tavern, publishing prices and arranging meeting times electronically."

At press time, authorities are pursuing an investigation into a drug trading and prostitution ring operated by Craig Newmark. His eponymous "list" provides access to every category of narcotics imaginable, as well as illegal sex-for-money services. Unless the DEA is given the authority to regulate Internet publication, warns Harrigan, the situation will only get worse.

Technologies used to send mail electronically, dubbed "e-mail," have also raised concerns. Experts predict that this tool will be exploited by pedophiles aroundQ:

Input type "Text" to have a blurred text, which dissappears onFocus?

Some websites have forms with input type="text". And inside these textboxes there is a blurred text, which says for example: "Enter your name here".
And then onClick or OnFocus or whatever, the text dissappears and you can type into the textbox.
Like the title of posting a question here at stackoverflow, same thing.
How is this done easiest way? Would prefer if there was not too much js involved.
Thanks

A:

That's not blurred text, it's called a "watermark."  You can create the same effect by using inline onfocus() and onblur() statements on your input.
For example:
<input type="text"
       class="watermark"
       value="Enter your name"
       onfocus="if (


Tag Archives: forecasts for the Year of the Wooden Horse

IT’S almost Chinese New Year, which, according to the lunar calendar, falls on January 31 this year. It’s the day when the auspicious Year of the Wooden Horse starts. But is it a year to look forward to, or will … Continue reading →with by slowing the printer down when temperatures reach unacceptable levels.
Another problem that can lower the reliability of printing systems is excessive idle time. One problem associated with idle time occurs when large particles within the pigmented inks settle on the backside of the printhead and block ink flow. A second problem associated with idle time is water loss. If the ink loses enough water during idle times, sludge can develop in the print cartridge and lead to failure. The ink will sludge faster if it sits in a small ink channel, separated from a larger reservoir.
Standpipe particles can produce print quality failures during assembly, which ultimately increases the cost of manufacturing. A flushing routine can be used in an attempt to remove particles from the standpipe prior


or printed onto paper. A further reliability improvement is provided through improved particle filtering. Each time a fluid is re-circulated through the system, it passes through the standpipe or plenum area and across the backside of the printhead. As the fluid moves through this region, particles that are trapped in the standpipe get swept out of the area and into a common chamber. From here, the fluid passes through a filter before it reaches the printhead again and any particles within the system are filtered out.a comprehensive and accurate view of a particular signaling network ([@b8]). Furthermore, manual reconstruction of such networks has been shown to be crucial in analyzing and interpreting structural features and global properties of signaling pathways ([@b93]; [@b75]; [@b92]; [@b12]).

On the basis of the current scientific and clinical interest in understanding the precise regulation and function of mTOR, we set out to communicate the mTOR network in both human- and computer-readable formats. Using CellDesigner (<http://celldesigner.org>), a modeling support software ([@b38]), we present a manually assembled map of the mTOR signaling network. This map complies with SBML and the systems biology graphical notation (SBGN) process diagram ([@b74]; [@b77]) for machine readable and graphical representation, respectively. Despite its static nature, a comprehensive map of molecular interactions would serve as a valuable


mTORC1 senses and integrates various environmental cues and intracellular signals to regulate cellular processes involved in the promotion of cell growth ([@b63]). To facilitate interpretation of the major signaling inputs to mTORC1 described below, and to encourage the use of the SBGN notation, we have drawn from the mTOR map a small-scale scheme of mTORC1 signaling events using the SBGN process diagram language ([Figure 3](#f3){ref-type="fig"}). This simplified mTORC1 map comprises 110 species, 77 reactions and 4 cellular compartments, and highlights positive and negative regulatory signals to mTORC1.

mTORC1 signaling is positively regulated by growth factors through the PI3K--AKT pathway (Growth Factor/Nutrient module in [Figures 2](#f2){ref-type="fig"} and [3](#f3){ref-type="fig"}). The binding of insulin to its cell surface receptor leads to the recruitment and phosphorylation of IRS-1, which promotes the recruitment andexact mechanism remains poorly understood (Growth Factor/Nutrient module in [Figures 2](#f2){ref-type="fig"} and [3](#f3){ref-type="fig"}). Two complementary studies have provided compelling evidence that the Rag family of small GTPases is both necessary and sufficient to transmit a positive signal from amino acids to mTOR ([@b71]; [@b101]). The current model proposes that amino acids induce the movement of mTORC1 to lysosomal membranes, where Rag proteins reside. More precisely, a complex encoded by the *MAPKSP1*, *ROBLD3* and *c11orf59* genes, interacts with the Rag GTPases, recruits them to lysosomes, and was shown to be essential for mTORC1 activation ([@b100]).

mTORC1 activity is sensitive to oxygen deprivation, and one pathway by which this occurs involves activation of the TSC1--TSC2 complex by REDD1, a hypoxia-inducible protein (Hypoxia module in [Figures 2](#f2){ref-type="fig"} and [3l](#f3){ref-type="fig"}; [@b11]). Newly synthesized


REDD1 was found to interact with 14--3--3 and relieve TSC2 from 14--3--3-dependent repression ([@b25]). mTORC1 also senses insufficient cellular energy levels through AMPK, a protein kinase activated in response to a low ATP/AMP ratio ([@b62]) and by LKB1-mediated phosphorylation (Low Energy module in [Figures 2](#f2){ref-type="fig"} and [3](#f3){ref-type="fig"}; [@b81]; [@b109]). Upon energy depletion, AMPK phosphorylates and activates TSC2, resulting in the inhibition of mTORC1 ([@b62]). The GSK3 may also be involved in the activation of TSC1--TSC2, as it was shown to phosphorylate TSC2 at Ser1337 and Ser1341 in response to AMPK-mediated TSC2 phosphorylation (Wnt module in [Figures 2](#f2){ref-type="fig"} and [3](#f3){ref-type="fig"}; [@b61]). Site-specific phosphorylation of Raptor also has an important role in the activation of mTORC1 in response to energy depletion. Indeed, low energy status promotes Raptor phosphorylation at Ser722a wide variety of upstream signals.

Downstream targets of mTORC1 signaling
--------------------------------------

As described above, mTORC1 responds to diverse external and intracellular signals to promote anabolic and inhibit catabolic cellular processes ([@b37]). Under favorable conditions, mTORC1 promotes protein synthesis, cell growth and proliferation ([@b84]). Conversely, various cellular stresses inhibit mTORC1 signaling to reduce biosynthetic rates and allow initiation of macroautophagy. To review major output responses from mTORC1, we have drawn a reduced version of the mTOR map based on central mTOR network components using the SBGN activity flow diagram language ([Figure 4](#f4){ref-type="fig"}). This simplified map also highlights the architecture of mTORC1 signaling and underscores the flow of positive and negative regulatory signals, which are briefly discussed in the last section.

mTORC1 regulates protein synthesis via phosphorylation of both S6K1 and 4E-BP1 (Cap-dependent


Martin Giroux for critically reading this paper and for helpful discussions. EC is supported by training grants from the Japan Society for the Promotion of Science and the Canadian Institutes of Health Research. PPR holds a Canada Research Chair in Signal Transduction and Proteomics, and a Career Development Award from the Human Frontier Science Program. Research in PPR laboratory is funded by a Terry Fox Foundation grant provided through the Canadian Cancer Society Research Institute. CP holds a Canada Research Chair in Immunobiology. MT holds a Canada Research Chair in Intracellular Signalling.

*Author contributions:* EC, CP, PR and HK conceived the idea of the mTOR map. EC assembled the map and coordinated the project. SG, YM and SL provided guidance for analyses. HK, YM and SG developed the *Payao*(psycho)linguistic type that make claims about the computations and representations that constitute grammar and aspects of language use (referred to as "Computational-Representational" (CR) Theories)" in relation to "theories that study the structure and function of the brain coming from the Neurobiology of Language (NB) and that are more implementational in character." Further, they discuss how CR-type of theories are currently more fine-grained than the current theories on how the linguistic representations and computations are realized in the brain (NB-theories). Under Poeppel and Embick\'s ([@B69], p. 104) and Embick and Poeppel\'s ([@B23], p. 361) view, what makes the unification of these two theories challenging is the *Granularity Mismatch Problem* (GMP), which refers to the fact that linguistic and neurolinguistic studies of language operate with objects of different "conceptual granularity."


linguistic phenomena, coreference and negative polarity item licensing, that are conceptually similar. Both coreference and negative polarity licensing can involve long-distance backward dependencies, where the licensee or dependent element occurs linearly before its licensor (although this configuration is not necessary for any of the two phenomena). Theoretical studies treat backward dependencies the same way as forward dependencies as structural hierarchy is the only important factor rather than linear precedence. The reasoning behind both ERP experiments is to examine if the strategies employed by the parser in the online interpretation of these two types of backward dependencies are similar, despite the different nature of the relation between the dependent element and its licensor. Even though the exact nature of the dependencies is different, both dependencies are restricted by syntacticbetween the two languages, we must conclude that they depend on the question formation strategies that are available to native speakers. From a theoretical point of view, it is expected that regardless of the question formation options that each language contains, *in-situ wh*-questions should be parsed similarly, namely, they need to establish dependency in the left periphery. This hypothesis considers the scenario where the grammar and the parser proceed hand-in-hand. The alternative would be an approach that shows an asymmetry between what is expected by theoretical linguistics research and what the real-time evidence shows, where the predictions for the performance side of language would be based on experience or usage-based information. If results come up differently for the two languages, it would mean that the existence of more


complexity in real-time parsing: the storage cost and the integration cost, which draw on the same pool of working memory resources. Storage costs refers to the cost of keeping an element actively stored in memory while it cannot be interpreted and while other information in the sentence is being processed. The integration cost, on the other hand, refers to the cost of integrating a syntactic prediction at the time it can be satisfied. Further, these costs are both affected by locality, which is measured in relation to the number of new discourse referents being processed[^6^](#fn0006){ref-type="fn"}. With respect to the processing cost that we refer to when the licensor in (10) is finally parsed, we specifically refer to the integration cost, which in this sentence is connected to theintegration of the NPI with the licensor at the time the prediction for the appearance of the licensor is finally met. In previous ERP studies (e.g., Fiebach et al., [@B24]; Phillips et al., [@B66]), this integration cost has been shown to elicit a P600 at the position where the syntactic prediction is met. Further, as noted in footnote 4, its amplitude has been shown to reflect the degree of difficulty of the syntactic integration at hand; therefore, one would expect that a higher integration cost will be shown in terms of differences in the amplitude of the elicited ERP component.

### Paradigm selection and materials\' design

In order to test the described contrast and implement the effects of increasing the linear distance between the NPI and negation (i.e., the licensor),


Pablos et al. (submitted) introduced conditions that added one to two modifiers at either A or B positions in (10). These conditions were compared at the licensor position (i.e., negation) with a control such as (9b), where no additional material was introduced. As mentioned in the section that discusses the challenges for theoretically informed experimental research, the experimental paradigm must be carefully controlled to avoid introducing differences that can affect the results: the modifiers that were included always consisted of three words each and had no possible interference in the interpretation of the NPI besides delaying the appearance of negation[^7^](#fn0007){ref-type="fn"}. In (11a) and (11b), we reproduce examples of the experimental materials with the modifiers that were included at the A position. Again, it was expected that this contrasttheir baseline condition in (9b).

The statistical analysis of the data confirmed the presence of a significant central anterior negativity in the 200--600 ms time window at the position of negation when the control sentence in (9b) was compared to conditions (12a) and (12b) at negation. When (9b) was compared to (11a) and (11b) conditions, only a lower, non-significant difference emerged. As expected, the amplitude of the negativity showed a correlation with the position and number of modifiers in the sentence with respect to the position of negation. When modifiers are introduced at the main clause following the verb *is* (i.e., position B), the amplitude of the central anterior negativity was bigger than when modifiers are introduced within the embedded clause after the NPI (i.e., position A). This shows


the verb)[^8^](#fn0008){ref-type="fn"}.

In the data from Pablos et al. (submitted), we take the beginning of the dependency to be marked by the NPI (i.e., the licensee) and the end marked by negation (i.e., the licensor). The position of negation is therefore the position where the dependency can be completed or finally integrated. It might be reasonable to think that the observed central anterior negativity marks the overall integration of the licensor for the NPI in sentences when the licensor-licensee distance is longer relative to the control. The size of the ERP amplitude is taken to reflect the level of disruption that additional material can cause in the search for a licensor. The fact that the effect correlates with the position of the intervening material (i.e., its size is relativeto the position where the licensor is most likely to occur) suggests that structural conditions play a role in this process. As discussed in the section on NPI dependencies, previous studies that examined short vs. long-distance *wh*-questions (see Fiebach et al., [@B24]; Phillips et al., [@B66]) have shown the elicitation of a P600 at the verb where the dependency is completed and have interpreted it as an integration cost related to the integration of the syntactic prediction. The fact that the type of dependency we examined is of a slight different nature (i.e., on the syntax-semantics interface) might have contributed to having a different type of ERP component elicited. Again, it should be emphasized that the study by Pablos et al. (submitted) does not examine cases of licensing


item and the left-periphery.

As seen in the previous sections on the Mandarin and French experiments, we matched the experimental paradigms that we used for French and Mandarin as closely as possible bearing in mind the differences between the two languages. This strong parallelism provided us with the opportunity to see which effects were maintained across languages despite their differences and which effects could connect to the restrictions imposed by the research question that we pursued and the experimental technique we used. For example, the timing and length of the observed effects did not always coincide for both languages. This is very likely to be dependent on specific characteristics of the language and the data used, which point to several processes occurring at same time (e.g., dependency completion, referentialsay I can do it, when I
haven't yet. BUT knowing that I can quickly learn and have talked up the
complexity so that I have enough time to raise the bunny to be a rabbit before
pulling it out of the hat.


DC-9 and Boeing 737 aircraft.  Mainline service was downgraded to Continental Express service in the late 1980s using Beechcraft 1900 turboprop aircraft.  Service to Flint and Chicago Midway also existed in 1992.  The airline left MBS in the mid-1990s and returned in 2002. Service was dropped to Cleveland again in 2003.
Northwest Airlines was a major player at MBS during the late 1980s until their merger with Delta in 2008.  In their 20+ years at MBS, Northwest served Detroit & Minneapolis with a fleet of McDonnell Douglas DC-9 series aircraft along with the Boeing 727 and Airbus 319 & 320. Northwest Airlink linked MBS to Flint, Lansing and Alpena throughout the 1980s with turboprop aircraft and eventually supported mainline Northwest with CRJ service to Detroit,of the  District was about 83,000 in 2011. The much larger area referred to as the Cotswolds encompasses nearly , over five counties: Gloucestershire, Oxfordshire, Warwickshire, Wiltshire, and Worcestershire. The population of the Area of Outstanding Natural Beauty was 139,000 in 2016.

History
There is evidence of Neolithic settlement from burial chambers on Cotswold Edge, and there are remains of Bronze and Iron Age forts. Later the Romans built villas, such as at Chedworth, settlements such as Gloucester, and paved the Celtic path later known as Fosse Way.

During the Middle Ages, thanks to the breed of sheep known as the Cotswold Lion, the Cotswolds became prosperous from the wool trade with the continent, with much of the money made from wool directed towards the building of churches. The most


It is well recognized that hydrogen fuel generated from renewable power would be a desirable option to continued use of fossil fuels. Hydrogen powered fuel cells are developing rapidly, are more efficient than internal combustion engines, and have only water as an emission. Unfortunately, hydrogen storage systems suitable for automotive and other small-scale industrial or residential applications remain elusive. Solid state hydrogen materials such as metal hydrides or chemical hydride are some of the best potential materials for solving this problem. Unfortunately these materials have their own problems including poor reversibility, unacceptable reaction kinetics, and inadequate thermal conductivity. A cursory review of known hydrides reveals that materials with a high hydrogen content react at thermodynamically difficult temperatures and/or pressures whereas those with reasonable re/dehydrogenation contain little hydrogen. Hydride-basedWhian Whian State Conservation Area

Whian Whian State Conservation Area is  one of the protected areas of New South Wales, operated by the NSW National Parks and Wildlife Service.

The Conservation Area is west of Byron Bay, New South Wales and north of Lismore, New South Wales, in the Northern Rivers region of New South Wales.

The Conservation Area lies within the Nightcap National Park and both areas are Gondwana Rainforests of Australia World Heritage Sites. A main attraction in the park is Minyon Falls

See also
 List of reduplicated Australian place names

References

Category:Northern Rivers
Category:State conservation areas in New South Wales


Megaupload founder and web tycoon Kim Dotcom is launching registration for his New Zealand political party on Monday. Tickets for his 40th birthday, coinciding with the launch, went in minutes, with more than 15,000 people planning to attend.

Dotcom, born in Germany as Kim Schmitz, told The Associated Press in an interview published Tuesday that he is founding and funding the party, but will himself not stand as a candidate. From Monday a party website and mobile app will be launched, and will begin registering members. By law, New Zealand requires 500 paid-up members to be registered before a party is formed.

While a resident of New Zealand, Dotcom is not able to stand as a candidate for political office as he does not have citizenship.

“The party website with informationQuantification of active ingredients in semi-solid pharmaceutical formulations by near infrared spectroscopy.
Near infrared (NIR) spectroscopy is increasingly gaining significance in the pharmaceutical industry for quality and in-process control. However, the potential of this method for quantitative quality control in pharmacies has long been neglected and little data is available on its application in analysis of creams and ointments. This study evaluated the applicability of NIR spectrometer with limited wavelength range (1000-1900nm) for quantitative quality control of six different dermatological semi-solid pharmaceutical preparations. Each contained a frequently used active ingredient in a common concentration either in a water-free lipid base or in an aqueous cream matrix. Based on direct NIR transflectance measurements through standardized glass beakers and partial least squares (PLS) multivariate calibration, quantitative models were generated comparing several


Elle Fanning, and more.

The story and the actors who worked to make this film so emotional and gripping, despite being a biography, should be commended, first and foremost. The starstudded cast are a seemingly perfect fit for the world this docudrama presents to us — with each character coming across authentically. Each of these characters feel like real people, and we, the viewers, are just peeking into the window of their lives as they deal with the blacklist, and not only what it means for Trumbo, but his family and friends.

People come and go in their lives, and these characters deal with hardship in a realistic and gripping way. Part of this incredible realism comes from the excellent writing, attributed to John McNamara, who has worked on variousday. Every surgeon who uses blue dye should be cognizant of the potential adverse reaction to isosulfan blue and treatment for such a potential fatal reaction. A complete lymph node dissection is done if the SLN is found to be positive. Elective lymph node dissection should not be done if SSL can be done as a staging procedure. It is important for investigators involved with SSL to follow the clinical outcome of their patients so that the role of SSL can be further defined.


india

Updated: Mar 25, 2019 23:03 IST

As many as 31 properties worth over crore belonging to separatists leaders of Jammu and Kashmir have been “identified” for attachment as “proceeds of crime by enforcement agencies, a senior MHA official who did not want to be identified said.

The properties earmarked for attachment includes the Islamabad house of Hizbul Mujahideen chief Syed Salahuddin. He is already a designated as terrorist by the United States and India. “New Delhi will ask Pakistan to attack the Salauddin’s property as ‘proceeds of crime’,” a second senior MHA official who did not want to be named said. “If Pakistan refuses, India is free to raise the issue at appropriate forum, including the Financial Action Task Force (FATF),” he said. Pakistan is in the “Greylist” of FATF.

Theof stories from the Elite:Tales From The Frontier anthology and a part from Allen Stroud's Elite:Lave Revolution.Dr Who veteran Penny MacDonald has been confirmed to narrate at least half of the anthology stories and Kate Russel's Elite:Mostly Harmless is to be recorded in London and will feature a section read by David Braben.Until next time Commanders...


  Sincerely,
STATE OF TEXAS  §
                §
COUNTY OF BEXAR §

     Before me, the undersigned notary public, on this day personally appeared P.
Brook Swilley, known to me to be the person whose name is subscribed below,
who on her oath stated and deposed as follows:

     My name is P. Brook Swilley. I am over 18 years of age and am competent to
make this affidavit. I am a senior associate with the firm of Brett Reynolds &
Associates, P.C. and an attorney for Appellants AutoZone, Inc. and AutoZoners,
L.L.C., who are Appellants in Cause No. 04-15-00307-CV pending in the Fourth
Court of Appeals, sitting in San Antonio, Texas. I haveHome&raquoSafety Management Group (SMG) – One of America’s Largest Privately Held Safety Companies

Safety Management Group (SMG) – One of America’s Largest Privately Held Safety Companies

Safety Management Group was formed in 1990 as a safety services provider for an Indianapolis-based insurance broker. We soon developed a comprehensive Contractor Safety Management Process (CSMP) for a global pharmaceutical company and used it to manage contractor safety for the Owner Controlled Insurance Program (OCIP) at our client’s five Indiana plant sites. Decades later, we continue to support their program.

SMG has since become one of the nation’s largest privately held professional safety service companies. Our services now encompass most aspects of safety for clients of all sizes in many industries. Whether you need safety consulting assistance, project safety staffing services, safety training, a


% File src/library/stats/man/plot.spec.Rd
% Part of the R package, http://www.R-project.org
% Copyright 1995-2007 R Core Team
% Distributed under GPL 2 or later

\name{plot.spec}
\alias{plot.spec}
\alias{plot.spec.coherency}
\alias{plot.spec.phase}
\title{Plotting Spectral Densities}
\description{
  Plotting method for objects of class \code{"spec"}.  For multivariate
  time series it plots the marginal spectra of the series or pairs plots
  of the coherency and phase of the cross-spectra.
}
\usage{
\method{plot}{spec}(x, add = FALSE, ci = 0.95, log = c("yes", "dB", "no"),
     xlab = "frequency", ylab = NULL, type = "l",
     ci.col = "blue", ci.lty = 3,
     main = NULL, sub = NULL,
     plot.type = c("marginal", "coherency", "phase"),
     \dots)

plot.spec.phase(x, ci = 0.95,
          has been set, when it is
    \code{"dB"}.  Only valid for \code{plot.type = "marginal"}.
  }
  \item{xlab}{the x label of the plot.}
  \item{ylab}{the y label of the plot.  If missing a suitable label will
    be constructed.}
  \item{type}{the type of plot to be drawn, defaults to lines.}
  \item{ci.col}{colour for plotting confidence bar or confidence
    intervals for coherency and phase.}
  \item{ci.lty}{line type for confidence intervals for coherency and
    phase.}
  \item{main}{overall title for the plot. If missing, a suitable title
    is constructed.}
  \item{sub}{a sub title for the plot.  Only used for \code{plot.type =
      "marginal"}.  If missing, a description of


for the time being. The Padres have interesting pieces, but few surefire talents on the staff.

Among the options, Richard is clearly the most proven commodity. He might not have the promise or potential of guys like Dinelson Lamet or Luis Perdomo, but he’s the only one that is currently guaranteed a spot in the rotation.

Richard throws a hard curve ball, and is especially adept at producing ground balls. He’ll have to be at his best if the Padres want to compete in the wild, wild NL West.

Image Source: Chris Humphreys/USA TODAY Sports

28. Anthony DeSclafani — Cincinnati Reds

After missing all of 2017, DeSclafani looks to bounce back in a big way for a Reds team that direly needs help on the mound. The 27-year old from the University ofof passenger rail services require high numbers or volumes of passengers to use their service to be commercially viable. If only a small number of passengers wish to travel on a single train at one time this can create significant operational costs for the service operator. Due to these concerns there is potential for rail network operators to restrict or limit the number of trains available to passengers in an attempt to reduce operational costs and to boost passenger numbers on each train. This however has the effect of reducing the convenience of the service for passengers, who become more likely to resort to using their own cars for transportation.
An improved transportation system that addressed any or all of the above problems would be of advantage. Specifically a


of things, it is easy to overlook the layered nature of this role. An actress playing a struggling actress has been seen before, but in scenes such as when the character of Mia is acting out a scene crying down the phone, we see Mia the character in the film, plus Mia the actress playing a role within the film, and of course Emma Stone encompassing all of these things. The devastating “Audition” scene gives her the chance to show some acting chops as well as her impressive pipes, and is one of the most devastating, yet powerfully uplifting moments of the entire year. Sure I have La La Land bias, but this film, and this performance in particular, is amazing.

2. Hayley Squires, I, Daniel BlakeHaving only caughtJeff Greenfield is a five-time Emmy-winning network television analyst and author.

Confirmation hearings for Judge Brett Kavanaugh will, if past is prologue, subtract significantly from the public understanding of what a Supreme Court justice is supposed to do. Senators will invoke impressive-sounding principles with the weight of cotton candy. We will hear that “judges should not legislate from the bench,” even as no one will discuss when exactly the Supreme Court is supposed to have done that in the past 50 years. We will hear platitudes such as the one offered by John Roberts, when he compared a judge to an umpire who calls “balls and strikes,” ignoring that in baseball, umpires have radically different strike zones. We will hear calls for “judicial restraint,” which translated means, “I want


prove.
In addition, Section
21.02 does not give rise to similar concerns about statutory breadth and
potential unfairness expressed in Richardson.
 Because the statute in Richardson encompassed approximately 90 predicate
drug crimes that were not all morally equivalent or conceptually similar, the
risk of dispensing with unanimity on the predicate acts was too great.  By contrast, the predicate acts in Section
21.02 are sufficiently equivalent to justify the Legislature’s decision to
dispense with unanimity on the predicate acts.
The lack of jury unanimity regarding the specific acts constituting the
required minimum of two sexual abuse acts raises no concern about fundamental fairness
given the circumstances.
Like Richardson,
Rabago is also distinguishable from
this case, so much so that its reasoning is inapplicable in this case.  In Rabago, the Hawaii Supreme Court struck down a
statute similar to Section 21.02.  103
Hawaii 236, 81 P.3d15
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1.6,18.6,,,
1.5,23.5,19.7,19.2
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output file1
6174,15,3,1.6,1.7,1.8
6176,17,5,1.6,1.5,1.3

output file2
6174,15,3,19.5,23.2,26.5
6176,17,5,18.6,23.5,26.8

output file3
6174,15,3,0,0,28.3,27.0
6176,17,5,0,0,19.7,19.2

output file4
6174,15,3,0,0,27.0,25.4
6176,17,5,0,0,19.2,18.5

code used
The code works almost fine, merge the csv files and output the 4 files requerides, but there is a problem for files 3-4, when there is empty values.
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each of the treatments were compared using the Student *t*-test \[[@B58-molecules-19-16573],[@B62-molecules-19-16573]\].

4. Conclusions
==============

α-Phellandrene and the essential oil of *C. rhamnifolioides* could find application in the control of *A. aegypti,* since both inhibit the oviposition of females at the breeding sites and kill mosquito larvae before they become adults. The retention of the larvicidal and oviposition deterrent activities of the essential oil during storage demonstrates that *C. rhamnifolioides* leaf oil could be used in the long term to combat the spread of the dengue mosquito. The mechanism of action of the leaf oil may be associated with its ability to inhibit trypsin-like activity in 4th instar larvae of *A. aegypti.*

The authors wish to thank FACEPE/PRONEX- APQ 0981-1.06/08 and INCT Dengue (CNPq and FAPEMIG) for financial assistance, and CNPq, CAPES andit began its ocean friendly restaurants campaign in April 2016.

Pine said she listed the organization on the bill because it’s already tracking restaurants that take measures to eliminate nondegradable waste. She said the bill would have to be amended, perhaps tasking the city’s new Office of Climate Change, Sustainability and Resilience with defining “ocean friendly” and certifying restaurants.

“We would hope that they do the best they can do mirror our program,” Bergstrom said. “It’s exponential what is washing up on our beaches. Sure a lot isn’t coming from Hawaii but as an island state… we’re going to make the change to make sure that were not the ones contributing to it.”


and position such a committee and how you would thoroughly describe its mission, purpose, or charge.

Paper#15132 | Written in 18-Jul-2015

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also highlight cutting edge approaches and to stimulate new concepts, methods and technologies within a sound biological framework of fundamental neuroscience. The conference will bring together expert scientists worldwide in an environment that is conducive to discussion and exchange of ideas. The exchange of ideas at this conference has been a driving force for the field. We expect the 2017 GRC on Excitatory Synapses and Brain Function will shape future scientific directions, and provide critical support for the mission of multiple institutes at NIH including NINDS, NIMH, NIDA and NIA.zinc ions across biological membranes [@bb0070], [@bb0075], [@bb0080]. In detail, the zinc transporters belong to two families, 14 human Zrt-/Irt-like proteins or solute carriers 39A (ZIP/SLC39A) and 10 zinc transporters or solute carriers 30A (ZnT/SLC30A) are known so far. ZIPs are zinc importers, which transport zinc ions into the cytoplasm, either from the outside of a cell or from an intracellular compartment. ZnTs, in contrast, are exporters, which facilitate zinc efflux out of the cell and into intracellular organelles and storage systems [@bb0085]. Current knowledge of structure, localization and function of the several zinc transporters has been reviewed in detail elsewhere [@bb0070], [@bb0075], [@bb0080], [@bb0085].

Apart from other effects, zinc ions promote proliferation *via* major protein kinase pathways such as the phosphatidylinositide 3-kinase (PI3K)/AKT cascade or the extracellular signal-regulated


of ZIP7 RNA and protein. Furthermore, an increased phosphorylation of ZIP7 protein was observed, which implies an activating post-translational modification on ZIP7. Other activated B cells, like *in vitro* generated activated B cells and *in vivo* activated and freshly isolated B cells, were examined as well to exclude further influencing factors. The latter were generated by *in vitro* CD40 ligand (CD40L)-CD40 ligation. Activation was determined by the expression of the activation marker CD69.

The observed increased amounts of ZIP7 protein and its increased phosphorylation could also be confirmed in these *in vitro* generated activated B cells. Both, *in vitro* generated activated B cells and freshly isolated CD69+ B cells showed accordingly elevated levels of free zinc, which is why activation and proliferation, involving an expression of CD69 in Bdepleted PBMC, equaling a relative expression of 1, normalized to the housekeeping gene PBGD. Mean values + SEM of *n* = 9 (A) and *n* = 7 (B) are shown (\* *p* \< 0.05, Student's t-test).Fig. 4

The relative RNA expression of various zinc transporters was found to be altered in the LCL compared to that of T cell depleted PBMC. Expression of ZIP importers is shown in [Fig. 4](#f0020){ref-type="fig"}A and ZnT exporter expression is presented in [Fig. 4](#f0020){ref-type="fig"}B. The lysosomotropic agent applied for T cell depletion did not itself interfere with the RNA quantification. Hence, the treated PBMC could be used for normalization. The LCL significantly upregulated the zinc importers ZIP7 and ZIP14 ([Fig. 4](#f0020){ref-type="fig"}A) on RNA levels compared to the T cell depleted PBMC, whereas the expression


[@bb0120] and malignant ovarian tumors [@bb0265]. Inconsistent studies indicate at least an effect of malignancy on the zinc level in pancreatic cancer, as they show either elevated [@bb0125] or decreased zinc levels [@bb0270]. Prostate carcinoma cells have been well studied regarding their zinc homeostasis and they are an outstanding exception. They downregulate their ZIP4 expression [@bb0275] and show decreased concentrations of zinc [@bb0280]. This discrepancy to the behavior of other tumors might be due to the fact that zinc levels in normal prostate tissue exceed those of other soft tissues with 1.018±0.124 mg zinc/g dry tissue [@bb0285]. Numerous studies also indicate an association between the aberrant expression of certain zinc transporters and malignancy in tissue samples from cancers and cell lines. The higher intracellular zinc levels might resultto feel important. So that was my mission going into Club Babe’s. And I’ll admit it wasn’t coasting on all cylinders when I came in; it was in dire need of some changes. So I’m going to walk you through some of what we did in the two years that I’ve been there which has doubled its sales with the same staff. We raised the standards there. We got employees to understand that they were going to be supportive of one another. One thing I did, and I don’t know if anyone else has tried this, but I brought in psychologists to do assessments. I needed to know our employees’ capabilities and attributes and their pathos, and the other talents they bring to the table before I pay


the hospitality standards. And then your customers will change with you. They’ll hold your club to a higher standard.

DC GlennI’ve been in the strip game since 1989. I started as a DJ at Magic City in Atlanta. Fast forward three years, one night I went home to write a song about what happens at Magic City on a Friday night and called that song, “Whomp, There It Is” and the rest is history. The funny thing is how many people think that’s the most wholesome song in the world. It’s amazing to me even today. That song is about my friends and me on a Friday night. So I’ve seen a lot in my almost 30 years, but the strip club industry has always been good to me.Yeah, there are some rules that still apply. A few rules. But in 2016. if you are not on the internet in a big way, and you don’t have your sites optimized, and showing up on the first page of Google, then you’re leaving a lot of money on the table. You know, one of the first things I did when I branched out into marketing reached out to ED’s Club Bulletin Magazine. I knew that if my club wanted to be taken seriously, we had to be in this magazine. For an urban club, that helps tremendously because this sector is not well-known at Expo, and because our club was being featured in the magazine it helps our exposure within the industry tremendously. Look, as club owners


you are aware that bad marketing results in your money being left on the table. As club owners and executives, urban or traditional, we have to adapt to the times to become successful.

Ryan WeaverThe Onyx brand was established from the foundation of Rick’s Cabaret, which is great service, respect, and catering to our guests by making them feel like family. The Onyx concept embraced certain elements of the urban club model, mainly the music and the type of entertainers. We were still very much focused on guest relations, but we added elegance to that model, which was instilled by Rick’s Cabaret. As Jack and DC explained, with urban clubs, social media is critical. I can’t say enough how important it is. More than radio, more than print, socialwhether palladium-gold nanocatalysts could convert glycerol, a waste byproduct of biodiesel production, into high-value chemicals.

In scientific parlance, the data from the study produced a "volcano plot," a graph with a sharp spike that depicts a "Goldilocks effect," a "just right" balance of palladium and gold that is faster -- about 10 times faster -- at converting glycerol than catalysts of either metal alone.

"We've now seen this volcano plot at least four times now, first with TCE, then with the dry cleaning contaminant 'perc,' and more recently with chloroform and nitrites," Wong said. "The remarkable thing is that the reaction, in each case, is very different."

In previous studies, the nanocatalysts were used in reduction reactions, chemical processes marked by the addition of hydrogen. In the latest tests on glycerol


thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particlespolishing uniformity is to remove the substrate from the polishing apparatus and examine it. For example, the substrate may be transferred to a metrology station where the thickness of the substrate layer is measured, e.g., with an ellipsometer. Unfortunately, this process can be time-consuming and thus costly, and the metrology equipment is costly.
One problem in CMP is determining whether the polishing process is complete, i.e., whether a substrate layer has been planarized to a desired flatness or thickness. Variations in the initial thickness of the substrate layer, the slurry composition, the polishing pad condition, the relative speed between the polishing pad and the substrate, and the load on the substrate can cause variations in the material removal rate. These variations cause variations in the time needed to reach


the polishing endpoint. Therefore, the polishing endpoint cannot be determined merely as a function of polishing time.
One way to determine the polishing endpoint is to remove the substrate from the polishing surface and examine it. For example, the substrate may be transferred to a metrology station where the thickness of a substrate layer is measured, e.g., with an ellipsometer. If the desired specifications are not met, the substrate is reloaded into the CMP apparatus for further processing. This is a time consuming procedure that reduces the throughput of the CMP apparatus. Alternatively, the examination might reveal that an excessive amount of material has been removed, rendering the substrate unusable.
There is, therefore, a need for a method of measuring in-situ the thickness and flatness of the substrate layer, andthe platen may be rotated to create the relative motion between the substrate and the polishing pad. The light source, e.g., a laser, may be connected to and may rotate with the platen.
In another aspect, the invention is directed to a method of measuring a characteristic of a layer on a substrate during chemical mechanical polishing. A surface of the substrate is contacted with a polishing pad, and a light beam is directed through a window in the polishing pad onto the substrate. The light beam moves in a path across the substrate surface. A plurality of intensity measurements are produced by the reflection of the light beam from the substrate. The intensity measurements are divided into a plurality of radial zones according to the radial position of


the third-most yards per play last season and is probably worse this season. Just because it's obvious doesn't mean it's not true.

Josh Jacobs, Oakland Raiders, vs. Broncos (ESPN projection: 15.8 points): One issue with declaring someone your 2019 fantasy ride-or-die? People overdraft him in leagues you are in and you don't have nearly enough shares of him as you'd like. Those jerks in my leagues are about to be handsomely rewarded, too, as Jacobs is going to get a ton of work against Denver. In a game Vegas has as a pick 'em, the game should be close enough for Jon Gruden to make good on his promise to keep riding Jacobs. In 2018, a running back got 20-plus touches against Denver 10 times. In all 10 ofstill introducing himself to his fifth set of teammates in less than three years, Duke Johnson Jr. should be getting a lot of work, both on the ground and in the passing game, as the feature back in a game with Week 1's highest over/under. ... For super-deep leagues or a cheap DFS punt, I bet we see more Ty Montgomery on Sunday than you'd think. Le'Veon Bell might not get a full workload early on and the Bills gave up the sixth-most RB targets last season, so 10 or so useful touches are possible for Montgomery.

Running backs I hate in Week 1

Le'Veon Bell, New York Jets, vs. Bills (ESPN projection: 16.4 points): Didn't see this one coming, did you? Didn't play in the entire preseason, didn't play


running back. NFL Nation Dolphins reporter Cameron Wolfe projected a timeshare in this Miami backfield at the beginning of August, before Drake suffered a foot injury that set him back roughly two weeks in the season prep process. Plus, this is an offensive line that just got worse with the trade of Laremy Tunsil. Kenyan Drake. Rap artist Drake. Matthew Berry. Matthew Perry ... we all had the same number of games with at least 15 carries last season. Lack of volume, bad O-line and a bad matchup. Other than that, Mrs. Lincoln, how do you like Drake this week?

Tarik Cohen, Chicago Bears, vs. Packers (ESPN projection: 11.5 points): David Montgomery impressed plenty this preseason and that has Cohen back in a role that is going to bematerial.'"

Zarrabi was forwarded Issler's email. In response, she posted the email on Facebook and quit her job.

I have recently been attacked and discriminated against by the owner of Dainty Hooligan. She went on our stores Instagram and deleted all of the pictures where I was modeling the clothing and then sent this email to my manager. I do not want to respresent [ sic] or support a business that has such archaic values and beliefs. THIS is the reason young girls have body image issues. This is disgusting. I quit immediately and I suggest that my friends and family do not support Dainty Hooligan. Love yourself, no matter what you look like.

Issler told The O'Colly, Oklahoma State University's student newspaper, that "I am accountable for the email that


be extra careful not to squash 'em.

UPDATE - Same Day, 1:30 p.m. - They're baaaaaaaaaaack. The ladybugs are swarming again at the same corner of my house. Now I'm wondering if they're moving into my walls for the winter. You know, cute can only get you so far. I still like 'em, but if they start any trouble, I'll evict their little polka-dotted asses.

One year we had a swarm of those cute little things move into the are, just before winter. At first it was really neat to see so many at once, then it got annoying, all over my car, my house, and in my house!!! 100's of them! Hanging on the curtains, the tassle of the ceiling fans, covering the TV screan, they were everywhere! We  self.clearInputFields_();
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to occupy any of the space inside the condenser, a desirable condition from an efficiency standpoint.

But to understand how all this works we’ll first have to gain an understanding of what is meant by density. A textbook would define it as the mass of a substance divided by the amount of space that that substance occupies. Let’s take steam and water for example. One pound of steam at 212°F forms a vapor cloud that occupies 26.78 cubic feet of space. If we condensed that pound of steam back into water at the same temperature, it would just about fit into a 16 ounce glass and occupy a mere 0.017 cubic feet.

The huge difference in their volumes is due to the fact that steam contains more than five timesthe heat energy that unheated water does. That energy makes the molecules in a cloud of steam more active, causing them to collide against each other with great force, spread apart, and occupy a larger space.

If you’re wondering what change in density has to do with vacuum in the condenser, allow me to offer an analogy. Ever canned any produce, like tomatoes, in glass jars to over-winter? Not likely, as this once common survival tactic has nearly become a lost art. But the vacuum created inside the condenser is much like the vacuum created within a mason jar during canning.

Inside the glass mason jar, a small space is intentionally left between the tomatoes and lid. During the process of boiling, or heat sterilization, this space fills with steam.


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				// Boolean attributes get special treatment (#10870)
				if ( jQuery.expr.match.bool.test( name )Genome-wide transcriptional response of Yersinia pestis to stressful conditions simulating phagolysosomal environments.
Yersinia pestis is a Gram-negative coccobacillus causing the dangerous disease, plague. Survival of Y. pestis within host macrophages is important in the initial stages of infection. In our present work, DNA microarray was used to determine the expression profiles of Y. pestis strain 201 in response to in vitro simulating conditions of Mg(2+) limitation, polymyxin treatment and oxidative stress that could be found in phagolysosomal environment. It was demonstrated that Y. pestis made appropriate adaptive/protective responses to survive the stressful environments. There are the induced expression of antiphagocytic factors and Mg(2+) transporters under Mg(2+) limitation condition, the stimulation of drug/analogue sensitivity and glycerol assimilation after polymyxin treatment, and the differential expression in genes encoding stress-responsive proteins, components


to all the ladies!! (or their husbands/ boyfriends who happen to read that;)

since there are so many foreigners working in Nantong I believe there must be quite a few women who came along and do not work for various reasons. And I am one of them. So! what do you do to pass the time?? i couldn't find any threads on that and i'm new in town and quite desperate for girlfriends I know Shanghai is brilliant when it comes to foreigners' clubs etc, I've heard girls are taking pottery, yoga, chinese, embroidery classes etc. Are there any places where they teach chinese to foreigners? I teach myself from a book and online but it's so much more fun when you're in a group. Give me your thouhtsNeutrophil attractant/activation protein-1 (NAP-1 [interleukin-8]).
Neutrophil attractant/activation protein-1 (NAP-1 [interleukin-8]) is an 8,400 D protein that is a chemoattractant and granule release stimulus for neutrophils. NAP-1 was first purified from culture fluids of lipopolysaccharide-stimulated human blood mononuclear leukocytes. It was subsequently isolated from lipopolysaccharide-stimulated lung macrophages, mitogen-stimulated lymphocytes, and virus-infected fibroblasts. Interleukin-1 or tumor necrosis factor induces NAP-1 mRNA in many cells, including monocytes, fibroblasts, and endothelial cells. NAP-1 belongs in a family of host defense small proteins, which have a degree of sequence and structural similarity. Noteworthy are the four half-cystine residues in each protein, which are in register when the protein sequences are suitably aligned. Based on cloning data and N-terminal sequence analyses, NAP-1 is secreted as a 79 residue protein after cleavage of a 20 residue


subsequently comparing the results with the updated *Ciona*KH (Kyoto Hoya) gene models \[[@B39]\] as reported in the ANISEED database (<http://www.aniseed.cnrs.fr/>). Out of 50 queries, only 26 yielded identifiable positive reciprocal best BLAST hits (Additional file [1](#S1){ref-type="supplementary-material"}).

For each reciprocal best BLAST hit, the corresponding *Oikopleura*genomic region, gene model and available ESTs sequences were collected and aligned to allow manual curation prior to cloning (data not shown). This procedure uncovered possible duplication events. In particular, we noticed that two different genes seemed to have been duplicated in *Oikopleura*, *Od-Noto15*and *Od-Calumenin*, while a third one, *Od-Noto9*, was found to be present in three copies. For this reason, in the case of these genes (Figures. [2](#F2){ref-type="fig"}, [3](#F3){ref-type="fig"} and Additional file [2](#S2){ref-type="supplementary-material"}) and a few more (data not shown), we resorted to thelarge superfamily of RNA-binding proteins, and more specifically to the K-homology (KH) RNA-binding domain \[[@B42]\]. We therefore rooted the tree with various deuterostome [h]{.ul}eterogeneous [n]{.ul}uclear [r]{.ul}ibo[n]{.ul}ucleo[p]{.ul}rotein [K]{.ul} (HNRNPK) protein sequences as outgroups. In most deuterostomes, a single copy of FUSEBP (*Noto9*) was found, while 3 FUSEBPs were found in mammalian genomes as well as in *Oikopleura*. However, our phylogenetic analysis suggests that the three copies found in mammals and *Oikopleura*arose from independent lineage-specific duplication events. In fact, vertebrate FUSEBPs group together with a statistical support of 98% with the neighbor-joining method and 100% of posterior probabilities as calculated by the Bayesian inference method, whereas Od-Noto9a, Od-Noto9b and Od-Noto9c group together with a statistical support of 92% and 100%, respectively, in a related yet separate tunicate monophyletic group. Despite


an area that seems to encompass the statocyst (Figure. [7O](#F7){ref-type="fig"}).

Considering the morphological similarities between the notochords of *Ciona*and *Oikopleura*, it seems surprising that the *Oikopleura*genome is apparently lacking roughly half of the notochord genes that we searched for, and that only a fraction of the *Ciona*notochord genes that possess identifiable counterparts (*i.e*., that are not divergent to the point of not being recognizable by our searches) in *Oikopleura*are expressed in the notochord. The *Ciona*notochord genes that we used as a reference for this study are active in many cellular processes; genes of still unknown function comprise the largest percentage, while genes encoding transcription factors and other nucleic acid-binding proteins make up the smallest portion (Figure. [8A](#F8){ref-type="fig"}). Only 21% of the genes of still unknown function (*Ciona Noto*genes; \[[@B59]\])services, and possibly free legal services, depending on her income level. These people will trample you if you attempt to stand up to them without someone to advise you who is an expert in your state’s laws, and familiar with your local court system. You absolutely need an attorney.

Second, avoid all contact with the holder. Even accidental contact can constitute a violation. This means that in addition to avoiding places where you have reason to believe she may be, you need to eliminate the chances of any other accidental contact.

Delete her email address from all of your accounts’ address books.

Disconnect from her on every social site on which you are a member. If possible, block her account from seeing your posts, as you can on Facebook. Also, disconnect


older than you, and someone female. Having people there to see what is happening will help to keep the elected judge honest. It shows him or her that you are not alone, and that what goes on in the courtroom will be seen and remembered by people who know you. It’s harder to do anything bad in front of witnesses who might go out and talk about it later. However, make sure your supporters know to not be disruptive or disrespectful. No sound should come from them once court is in session, and nothing loud enough to be clearly heard two rows over prior to that. Your folks should be dressed like they would if they were going to an acquaintance’s in-church wedding.

Do not dramatically change your appearanceThere are conventional techniques disclosed in Patent Documents 1 and 2, for example.
FIG. 1 shows a cross-sectional structure of a light emitting device employing a common organic electroluminescence element (organic EL element) and propagation of light. An electrode 102, a light emitting layer 103, and a transparent electrode 104 are stacked in this order on a substrate 101, and a transparent substrate 105 is provided on the transparent electrode 104. When a voltage is applied between the electrode 102 and the transparent electrode 104, light is radiated from a point S in the light emitting layer 103. The light enters the transparent electrode 104 directly or after being reflected by the electrode 102, and is then transmitted through the transparent electrode 104. The light transmitted through the transparent


Chartered Engineer (CEng)

Chartered Engineers (CEng) develop solutions to engineering problems using new or existing technologies, through innovation, creativity and change and/or they may have technical accountability for complex systems with significant levels of risk.

The CEng title is open to anyone who can demonstrate the required professional competences and commitment, as set out in the professional standard UK-SPEC. Individuals generally develop these through education and working experience.

The application process for CEng registration is more straightforward for those with exemplifying academic qualifications. For CEng this is one of the following:

An accredited Bachelors degree with Honours in engineering or technology, plus an appropriate and accredited Masters degree or Engineering Doctorate (EngD), or appropriate further learning to Masters level

An accredited integrated MEng degree

Please note:

If you gained academic qualifications which, at the timeAs previously reported, physical conditioning appears to be effective in modifying myocardial performance in the senescent heart. Because of the obvious importance of this area, we have undertaken to development of exercise models, varying age, duration, and intensity and type of exercise.


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(size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 41 thru_hole oval (at 20.000000 1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 2 thru_hole oval (at -20.000000 -1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 -0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 4 thru_hole oval (at -18.000000 -1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 -0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 6 thru_hole oval (at -16.000000 -1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 -0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 8 thru_hole oval (at -14.000000 -1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 -0.254000)) (layers *.Cu *.Mask F.SilkS))
  (pad 10 thru_hole oval (at -12.000000 -1.000000) (size 1.524000 2.286000) (drill 0.900000 (offset 0.000000 -0.254000))The mayor of Canada's most populous city is ordering the "anti-fun police" to stand down on a probe of seniors' euchre games in Toronto.

John Tory says city staff who were investigating a $1.25 buy-in for the games at a community centre should back off and let senior citizens play in peace.

A spokeswoman for Tory says staff were investigating the games as illegal gambling and ordered the buy-in lowered to 25 cents while the probe was underway.

Tory says he's sure that if there's any danger of "Las Vegas-style gambling breaking out en masse" in Toronto's community centres, the city will know about it.

He says there's more important issues to deal with in Toronto, so the Parks and Recreation department should reinstate the higher buy-in and just let the seniors


"If I could walk" "Oh" "You kow I'd ever lie" "Oz!" "Hey!" "Have a seat..." "Except." "We don't have any seats." "It's ok." "I'll just scrunch in." "Xander." "Why are you giving me a lap dance?" "What?" "I just like you." "Willow:" "And that's very beautiful." "I think it's great when two people like two people and want to be close to them instead of anyone else." "Hear." "Hear!" "Yeah." "Well put." "Hey." "Can I snag a sip?" " Sure." " Yeah." "You got it." "[Room Applauds]" "Thank you!" "Thank you." "We're here through Saturday." "Enjoy the veal." "Why are you guys so hyper?" "Hey!" "Speaking of people and things they do that aren't like usual." "anyone notice Buffy acting sort of different?" "Let's see." "Uh." "killing zombies...to do with this blasted glove." "Hey." "You're not the watcher of me." "Then go home." "But if you choose to stay." "Then work." "Ugh..." "It's late." "I'm tired." "What does he want from us." "Anyway?" "The number of a qualified surgeon to remove the British flag from his butt?" "My eyes are all blurry." "Ohh..." "Oh." "Stop." "Right." "Stop means no... and no means no." "So." "Um... stop." "Willow." "Xander." "You can stop your." "Uh." "Studying." "I've got what I need." "What have you got?" "Uh." "The probable location of the Glove of Myhnegon." "It's housed in the Von Hauptman family crypt." "Yeah." "That's that big one over at the Restfield Cemetery." "Yeah." "Well." "that's great." "Giles." "How'd you find it?" "I looked." "Where's Buffy at?" "Uh."


him myself." "Toting the popular and famous glove." "Angel." "[Strikes Ball]" "Guy like that." "with that kind of glove... could kill a whole mess of people." "Said the same thing to Buffy myself." "Weird how she didn't seem to care." "Buffy knew he was alive." "I can't believe her." "She says he's clean." "Well." "I say we can't afford to find out." "I say I deal with this problem right now." "I say I slay." "Can I come?" "You wanted to see me." "Mr. Giles?" "Yes." "I do apologize for bringing you in at this late hour." "Please." "A good watcher must be awake and alert at all hours." "Would you like some tea?" "God." "Yes." "Please." "I'm completely knackered." "I spent the afternoon training with Faith." "Shehave a medical emergency." "Sunnydale High." "Screw this waiting crap." "Faith." "If we leave." "Giles could die." "Yeah." "And he's going to have a whole lot of company." "unless I do something permanent." " Wait!" " For what?" "You to grow a pair?" "You handle the baby-sit." "and I'm gonna kill Angel." "Damn it!" "[Speaks Latin]" "Giles is gonna be psyched that we showed up stuffy old Mrs. Post." "Oh." "My God." "Sunnydale Medical..." "What happened?" "Giles." "Blunt object head trauma." "Notify E. R..." "we're bringing him in." "What happened?" "No time for this." "Wait..." "Buffy." "You must... must destroy the glove." "You want him to live?" "Get out of the way." "Use..." "living flame..." "Paramedic:" "Move!" "What happened?" "Your boyfriend's not as cured as you thought." "What


1504511 composite?
True
Is 46080854 a composite number?
True
Is 3883351 a prime number?
False
Is 11367659 composite?
True
Is 12456511 composite?
True
Is 47563795 composite?
True
Is 6636523 composite?
False
Is 613259 a composite number?
True
Is 8468353 a prime number?
True
Is 10869901 prime?
False
Is 321025771 prime?
False
Is 4986785 a prime number?
False
Is 364787281 a prime number?
False
Is 250990511 a composite number?
False
Is 226901 a prime number?
True
Is 4542803251 composite?
True
Is 3881803 composite?
False
Is 1159331 prime?
False
Is 727507 a composite number?
True
Is 25281221 composite?
True
Is 10371521 prime?
True
Is 962303 prime?
True
Is 3662443 a composite number?
True
Is 3906137 a composite number?
False
Is 13263529 a composite number?
False
Is 438607 a prime number?
False
Is 655391 a composite number?
True
Is 217727681 prime?
False
Is 110252209 prime?
True
Is 3942643 a prime number?
True
Is 585839 a prime number?
True
Is 127090087 a prime number?
False
Is 57066091 a prime number?
True
Is 4190617 composite?
False
Is 31408319 prime?
True
Is 27191 prime?
True
Is 20946649 composite?
False
Is 19904377 prime?
True
Is 1267859 a composite number?
False
Is 113937303 a prime number?
False
Is 138423331 prime?
True
Is 29170013 prime?
False
Is 283349 composite?
True
Is 368717 amay or may not be human. And there are outlaws outside the viewing dome. It’s the Seablite Gang:

For months, the Seablite Gang had terrorized the settlement, robbing every supply ship that floated our way. I had often wondered what would happen if I came across them.

He’s about to find out. He’s going to need to keep his wits about him. What happens next will shape the future for both Ty and Gemma and the whole subsea territory he calls home...


such algorithm starts from a predefined family of candidate contraction sets. Even though any connected set of vertices may form a valid candidate set, I opt for small well-connected sets, formed for example by pairs of adjacent vertices or neighborhoods. The algorithm then greedily[^2] contracts those sets whose local variation is the smallest. Depending on how the candidate family is constructed, the proposed algorithms obtain different solutions, trading off computational complexity for reduction.

#### Theoretical and practical implications.

Despite not providing a definitive answer on how much one may gain (in terms of reduction) for a given error, the analysis improves and generalizes upon previous works in a number of ways:

-   Instead of directly focusing on specific constructions, a general graph reduction scheme is studied featuring coarsening asrestricting the attention to constructions that satisfy additional properties (see Theorem \[theorem:eigenvalues\]).

One can also say something about the eigenvectors of $L_c$.

For every vector for which $x = \Pi x$, one has $$\begin{aligned}
    {{x}_{c}}^\top {{L}_{c}} {{x}_{c}} = x^\top \Pi L \Pi x = x^\top L x \quad \text{and} \quad {\widetilde{x}} = \Pi x = x. \notag\end{aligned}$$

In other words, reduction maintains the action of $L$ of every vector that lies in the range of $\Pi$. Naturally, after lifting the eigenvectors of ${{L}_{c}}$ are included in this class.

Coarsening as a type of graph reduction {#subsec:graph_coarsening}
---------------------------------------

Coarsening is a type of graph reduction abiding to a set of constraints that render the graph transformation interpretable. More precisely, in coarsening one selects for each level $\ell$ a surjective (i.e., many-to-one) map $\varphi_{\ell}:


aims to capture the global problem structure, whereas neglected details can be recovered in a local refinement phase.

Coarsening can be placed in the context of Scheme \[frm:matrix\_reduction\] by restricting each $P_{\ell}$ to lie in the family of coarsening matrices, defined next:

Matrix $P_{\ell} \in {\mathbb{R}}^{N_{\ell} \times N_{\ell-1}}$ is a coarsening matrix w.r.t. graph $G_{\ell-1}$ if and only if it satisfies the following two conditions:

-   It is a *surjective mapping* of the vertex set, meaning that if $P_{\ell}(r,i) \neq 0$ then $P_{\ell}(r',i) = 0$ for every $r' \neq r$.

-   It is *locality preserving*, equivalently, the subgraph of $G_{\ell-1}$ induced by the non-zero entries of $P_{\ell}(r,:)$ is connected for each $r$.

\[def:coarsening\_matrix\]

An interesting consequence of this definition is that, in contrast to graph reduction, with coarsening matrices the expensivev_j \in \mathcal{S}_z } \frac{\| X(i,:) - X(j,:)\|_2^2}{2\, |\mathcal{S}_z|}.$$ One then measures the quality of ${\widetilde{\mathcal{P}}}^{*}$ by examining how far the correct minimizer ${\mathcal{F}_{k}\hspace{-0.5px}(U_k,\mathcal{P}^{*})}$ is to ${\mathcal{F}_{k}\hspace{-0.5px}(U_k,{\widetilde{\mathcal{P}}}^{*})}$. @boutsidis2015spectral noted that if the two quantities are close then, despite the clusters themselves possibly being different, they both feature the same quality with respect to the $k$-means objective.

An end-to-end control of the $k$-means error is obtained by combining the inequality derived by @loukas2018spectrally, based on the works of [@boutsidis2015spectral; @yu2014useful; @martin2017fast], $
| {\mathcal{F}_{k}\hspace{-0.5px}(U_k,\mathcal{P}^{*})}^{\sfrac{1}{2}} - {\mathcal{F}_{k}\hspace{-0.5px}(U_k,{\widetilde{\mathcal{P}}}^{*})}^{\sfrac{1}{2}} | \leq 2 \sqrt{2} \, {\left\lVert{\sin{\hspace{0.0px}\Theta\hspace{-0.0px}\big( U_k, P^\top {\widetilde{U}}_k \big)}} \right\rVert}_F
$ with Theorem \[theorem:sintheta\]:

If $L_c$ and $L$ are $(\mathbf{U}_k,\epsilon_k)$-similar then $$\begin{aligned}
    \left( {\mathcal{F}_{k}\hspace{-0.5px}(U_k,\mathcal{P}^{*})}^{\sfrac{1}{2}} - {\mathcal{F}_{k}\hspace{-0.5px}(U_k,{\widetilde{\mathcal{P}}}^{*})}^{\sfrac{1}{2}} \right)^2 \leq \frac{ 8 }{\lambda_{k+1} - \lambda_{k}} \left( \sum\limits_{i \leq k} \lambda_i \left(\frac{(1 + \epsilon_i)^2}{\gamma_1}  - 1\right)  +


minimize an upper bound of $\epsilon$. To this end, two bounds are exploited: First, ${{L}_{c}}$ is shown to be $(\mathbf{R}, \epsilon)$-similar to $L$ with $\epsilon \leq \prod_{\ell} (1 + \sigma_\ell) - 1$, where the *variation cost* $\sigma_{\ell}$ depends only on previous levels (see Section \[subsec:sufficient\]). The main difficulty with minimizing $\sigma_\ell$ is that it depends on interactions between contraction sets. For this reason, the second bound shows that these interactions can be decoupled by considering each *local variation cost*, i.e., the cost of contracting solely the vertices in ${\mathcal{V}}^{(r)}_{\ell-1}$, independently on a slightly modified subgraph (see Section \[subsec:decoupling\]). Having achieved this, Section \[subsec:families\] considers ways of efficiently identifying disjoint contraction sets with small local variation cost.

Decoupling levels and the variation cost {#subsec:sufficient}
----------------------------------------

Guaranteeing restricted spectral approximation w.r.t. subspace $\mathbf{R}$ boils down tominimizing at each level $\ell$ the *variation cost* $$\sigma_{\ell} = \|\Pi_{\ell}^\bot A_{\ell-1}\|_{L_{\ell-1}} = \|S_{\ell-1} \Pi_{\ell}^\bot A_{\ell-1}\|_2,$$ where $L_{\ell-1} = S_{\ell-1}^\top S_{\ell-1}$ and $ \Pi_{\ell}^\bot = I - P_{\ell}^+ P_\ell$ is a projection matrix. Matrix $A_{\ell-1}$ captures two types of information:

1.  Foremost, it encodes the behavior of the target matrix $L$ w.r.t. $\mathbf{R}$. This is clearly seen in the first level, for which one has that $A_{0} = V V^\top L^{+\sfrac{1}{2}}$ with $V \in {\mathbb{R}}^{N\times k}$ being an orthonormal basis of $\mathbf{R}$.

2.  When $\ell>1$ one needs to consider $A_{0}$ in view of the reduction done in previous levels. The necessary modification turns out to be $A_{\ell-1} = B_{\ell-1} (B_{\ell-1}^\top L_{\ell-1} B_{\ell-1})^{+\sfrac{1}{2}}$, with $B_{\ell-1} = P_{\ell-1} B_{\ell-2} \in {\mathbb{R}}^{N_{\ell-1} \times N}$ expressed in a recursive manner and $B_{0}


In this manner, heavier edges connecting vertices that are well separated from the rest of the graph are contracted first. Heavy edge matching was first introduced in the algebraic multigrid literature and, perhaps due its simplicity, it has been repeatedly used for partitioning [@karypis1998fast; @dhillon2007weighted] and drawing [@walshaw2000multilevel; @hu2005efficient] graphs, as well as more recently in graph convolutional neural networks \citep{}.

-   *Algebraic distance.* This method differs from heavy edge matching in that the weight of each contraction set is calculated as $(\sum_{q=1}^Q (x_q(i) - x_q(j))^2)^{1/2}$, where $x_k$ is an $N$-dimensional test vector computed by successive sweeps of Jacobi relaxation. The complete method is described by @ron2011relaxation, see also [@chen2011algebraic]. As recommended by the authors, I performed 20 relaxation sweeps. Further, I set the number of test vectors $Q$ to equal theof work one does. The most important thing to keep in mind, according to hiring managers, is that companies judge a candidate based on their skill set and not on their ink.

For the longest time I was the type of person who felt that I needed other people to tell me what to do. It took the responsibility off of my shoulders. But I have also wanted a tattoo on my arm for a very long time. Various people in my life persuaded me not to. They told me that I would regret it; they tried to tell me how it looked. I was told that getting something like an arm tattoo made women appear trashy, homeless, uneducated, and undesirable. They told me how they saw women with


I saw them on the ground, I thought, 'That's somebody's child,' " Howard said. "The girl, she looked like she wanted to get up but couldn't."

Howard knelt by the female victim and held her until police arrived. Police suspect the female victim, who was shot in the torso and wrist, was a bystander caught in the crossfire.

"She kept saying, 'My stomach is burning,' " Howard said. "I just held her and tried to keep her calm."

McMullen said police were searching for three to four people who left the scene before officers arrived, describing them as "persons of interest." Police took one person into custody later Sunday evening, he said, but had not named him as a suspect.

Police searched the grass surrounding one of the bodies for shell casings,initial wager and is dealt five face-up cards from a standard 52-card deck, the player is allowed to discard and replace unwanted cards with replacement cards from the deck, resulting in a final card hand. The game then determines a poker-hand ranking of the final card hand and provides an award based on a pay table. The pay table includes a list of winning poker-hand rankings and the award for each ranking. The winning poker-hand rankings for a standard Jacks or Better video poker game include in order from highest to lowest: Royal Flush, Straight Flush, Four of a Kind, Full House, Flush, Straight, Three of a Kind, Two Pair and a Pair of Jacks or Better. Any poker hand having a ranking less than a Pair of


Q:

How to write an error struct which can contain different strongly typed enums as the error code?

I want to write an simple error struct which contains an error code of some kind and a std::string as the message. The error code could be a simple int, or any kind of strongly typed enum e.g.:
enum class NetworkErrorCode {
OK = 0,
CONNECTION_FAILURE,
EMPTY_RESPONSE,
HOST_RESOLUTION_FAILURE,
UNKNOWN_ERROR = 1000,
};

I could write a struct which has different overloaded constructors for each different enum it could contain which all convert them into int to store them. But in this case I would loose the possibility to compare the error code against the actual enum values later on. I would also need to write a comparison operator for each of the possible types.
I could also use templates likeit requires real participation from others.”

Essentially, NASA now seems to be asking academia, the private sector, and other national space agencies to bring ideas about building and using the lunar outpost.

Deep space transport

After establishing the gateway in the mid-2020s, NASA would next move to develop a transport system for human travel beyond the Earth-Moon system. The key component would be a 41-ton spacecraft that includes power systems and a habitation module to provide all of the food, health, and science needs of astronauts for long-duration missions in deep space. According to Gerstenmaier’s charts, which he stressed were provisional, this transport system could be launched as early as 2027.

After the delivery of an additional logistics module, by around 2029, NASA would plan to send a crew of four astronauts


be made. Part of the reason Gerstenmaier talked publicly about these plans Tuesday is that the agency must begin deciding what hardware will fly on the deep space gateway assembly missions in 2023 through 2025. Specifically, what power systems and what habitats are best suited to the task? “We are ready to start putting pencils to paper and cutting hardware for these missions,” he said.

NASA is also trying to convince the Trump administration that it has a sound plan to send humans into deep space. Vice President Mike Pence will probably have a few concerns with the plan outlined by Gerstenmaier. First of all, there are no human missions before about 2023, and Trump officials have made it clear they would like to see some kind of human20th anniversary of the Washington Principles. In 1998, 44 signatory countries made a commitment to track down stolen art in public museums and find settlements for the heirs of the Nazi victims. However, this commitment does not apply to privately owned art. In the last 20 years, Germany has "done far too little," Lauder told German newspaper Welt am Sonntag earlier in November.

JWC President Ronald Lauder, seen here in October with German Foreign Minister Heiko Maas at Berlin's first Orthodox rabbinical ordination since the Holocaust, says Germany has a "done far too little" about the Nazis' theft of cultural heritage

Hartmut Ebbing, the cultural policy spokesperson for the business-friendly Free Democrats (FDP) party, told DW that he "fully agrees" with Lauder that the issue of restitution is still being


"neglected" in Germany. As the country where the Holocaust took place, Germany has a "moral obligation" in the matter, he said.

Read more: What Nazis stole from synagogues during Kristallnacht

Cultural heritage legitimacy is 'up to us'

But that may be changing in the wake of increased public consciousness: The origin of paintings is now even the subject of several exhibitions, including a current show in Berlin. "The Lives of Images. Provenances in Museum Berggruen. Picasso-Klee-Braque-Matisse," shows the partly twisted and sometimes criminal paths in the histories of the exhibited works. From 2015 to 2018, experts examined whether 135 pre-1945 works from Jewish art collector Heinz Berggruen's former private collection were Nazi looted art. The works are now owned by the Prussian Cultural Heritage Foundation.

Watch video 03:52 Share Looted artworks returnedcalled upon to deal with questions relating to the restitution of looted art, to be unsatisfactory. He says that this is because it only becomes involved if both sides are active. Museums often say that the art is not looted, Ebbing says, "in which case procedures are not even initiated by the Commission." He says it's important that either side can call on the Commission. Lauder welcomes the fact that Monika Grütters, Minister of State for Cultural Affairs, wants to reform the Limbach Commission a second time. But this time, says the Jewish World Congress' Lauder, all controversial questions must be solved.

Cultural heritage expert Parzinger admits that it naturally hurts every museum to lose an art object, but "We don't want stolen things in our collections, no matter


\sum_{\substack{n = 1\\n \in 9,21,\ldots}}^\infty \frac{1}{n^2} - \sum_{\substack{n = 1\\n \in 11,23,\ldots}}^\infty \frac{1}{n^2}\\
&= \frac{1}{144} \sum_{n = 0}^\infty \frac{1}{(n + 1/12)^2} + \frac{1}{72} \sum_{n = 0}^\infty \frac{1}{(n + 3/12)^2}\\
& \qquad + \frac{1}{144} \sum_{n = 0}^\infty \frac{1}{(n + 5/12)^2} - \frac{1}{144} \sum_{n = 0}^\infty \frac{1}{(n + 7/12)^2}\\
& \qquad - \frac{1}{72} \sum_{n = 0}^\infty \frac{1}{(n + 9/12)^2} - \frac{1}{144} \sum_{n = 0}^\infty \frac{1}{(n + 11/12)^2}\\
&= \frac{1}{144} \left [\psi^{(1)} \left (\frac{1}{12} \right ) - \psi^{(1)} \left (\frac{7}{12} \right ) \right ] + \frac{1}{72} \left [\psi^{(1)} \left (\frac{1}{4} \right ) - \psi^{(1)} \left (\frac{3}{4} \right ) \right ]\\
& \qquad + \frac{1}{144} \left [\psi^{(1)} \left (\frac{5}{12} \right ) - \psi^{(1)} \left (\frac{11}{12} \right ) \right ]. \tag2
\end{align}
Two special values for the trigamma function are:
$$\psi^{(1)} \left (\frac{1}{4} \right ) = \pi^2 + 8 \mathbf{G} \quadCategorias

Autor: Rachel Belitardo

It is actually recommended to search for the typical net profit of your type of venture you'd like to carry out there inside your city.

Focus!

The National Method to the Survey of Fees and Indices of Civil Building – SINAPI – delivers month to month, for all people that choose to download (in PDF), the prices and indices of your civil construction.

Sad to say the tables are only available for download in PDF format, extremely hard to automate with Excel spreadsheets.

It is worth remembering the same enterprise, in different cities, can have various profitability.

The spreadsheet is filled with a study of the mid-level residential residential venture situated in Fortaleza (CE) and right here the net profit from 17% in this style of enterprise is thought of very


push your company ahead each day. It doesn't should be a big thing. Just some social sharing may be enough.

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Take into consideration new approaches to industry your solution. You'll find a lot of marketers out there marketing a great deal of solutions. You have acquired to discover a method to break as a result of the clutter and be noticed (and heard). Brainstorm on creative strategies toshowcase your solution the two on the net and in true existence. This could make each of the big difference.

Would you prefer to read a number of content articles on multi degree marketing and advertising? Then just click right here:

An excellent strategy to drop some weight is always to sign up for an internet based discussion board which is devoted to weight-loss. You will have the capacity to share your encounters with other individuals which consequently will inspire you to definitely keep on reducing weight. Message boards are an awesome destination to look for and provides information.

An excellent solution to drop some weight is always to minimize out every one of the soda you consume. Soda is loaded with sugar and carbs and many of us usually are


plates.

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Anybody impacted by cellulite difficulties. This may perhaps sound weird, but the truth is that kneading aids circulate blood by the body. This, in flip, assists the body break down all of these unsightly excess fat deposits that you're worrying in excess of.

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take it easy. It could be actually challenging to take it easy throughout an interview, but don't forget this: you'll both get the occupation, otherwise you is not going to. Your concentrate needs to be on presenting your most effective self, and be worried about no matter whether you are going to get the work later on on, when you are finished.

Put together your ideal ahead of time to the interview that you're happening. Which means that you could recite your responses in front of the mirror to obtain a superior plan of everything you need to say. Also, this may enable to ease a few of the stress that you simply may perhaps practical experience.

A terrific tip for just about any work is usually to have ideala juvenile, attends Midrose, which has about 70 students.

During the brief and bloody attack, another student tried to intervene and "pull the teacher and the other kid apart," Linscomb said.

That student wasn't hurt in the scuffle, and the teacher and the boy who attacked him both fled out of the classroom and into a courtyard. The teacher called 911. Students who witnessed the attack told police they saw the boy head north to a gate in the campus fence that led into the Bellevue Ranch neighborhood, Linscomb said.

Police found the teen about three blocks north of campus at a relative's home on Silver Spur Drive.

Officers found what appeared to be the boy's bloody clothes in the neighborhood along the youth's "escape route," Linscomb said. Late Wednesday, police had


police custody said he was a relative and the boy lived elsewhere in Santa Rosa with his parents.

The man, who didn't want to be identified, said his family was struggling to understand what took place with the youth and that he was "sorry it had gotten to this point."

Police don't yet understand what might have motivated the attack, Linscomb said. The boy didn't have a known history of violence, he said.

The stabbing elicited a large-scale police response.

The entire 980-student campus was on lockdown. Students were quarantined in classrooms with the blinds drawn, lights off and doors locked. They were instructed to stay quiet.

Wednesday afternoon, an officer placed yellow police tape around beams in the northern courtyard outside a door under the Midrose High School sign as a policeThe body will outline ways of a constitutional reform and provide recommendations on parliamentary and presidential elections

Saudi Foreign Minister Adel al-Jubeir

VIENNA, October 30. /TASS/. A special body will be established to launch political process in Syria, Saudi Foreign Minister Adel al-Jubeir said on Friday after the multilateral talks on Syrian settlement in the Austrian capital city Vienna.

He said participants in the talks had agreed to set up a special body that would outline ways of a constitutional reform and provide recommendations on parliamentary and presidential elections. In his words, these positions had been included in a final document.


a well defined manner, an area of $\approx$ 4188 deg$^2$. Spectroscopic plate 716 was the first spectroscopic observation that was based on the final version of the quasar target selection algorithm (Richards et al. 2002); however, the detailed tiling information in the SDSS database must be consulted to identify those regions of sky targeted with the final selection algorithm.

The two double-spectrographs produce data covering at a spectral resolution The data, along with the associated calibration frames, are processed by the SDSS spectroscopic pipeline (see Stoughton et al. 2002). The calibrated spectra are classified into various groups (e.g., star, galaxy, quasar), and redshifts are determined by two independent software packages. Objects whose spectra cannot be classified by the software are flagged for visual inspection. Figure 1 shows the calibrated SDSS spectra of four previously unknown catalogquasars representing a range of properties.

The spectrophotometric calibration has been considerably improved since DR1; details of the changes are given in Abazajian et al. (2004). The processed DR3 spectra [*have not*]{} been corrected for Galactic extinction; this is a change from all previous SDSS data releases.

Construction of the SDSS Quasar Catalog
=======================================

The quasar catalog was constructed in three stages: 1) Creation of a quasar candidate database, 2) Visual examination of the candidates’ spectra, and 3) Application of luminosity and emission-line velocity width criteria.

Because of the evolution of the project software during the early phases of the SDSS, spectra of quasars could be obtained based on photometric measurements/target selection criteria that are not identical to the final products. The DR3 catalog was prepared using Version 5.4 of the photometric pipeline code. (The differences between this