where we are."

"C'mon, ya saffage deffils!" Kruger shouted. "C'mon ya sonsabitches."

Eli sat calmly at the steering oar as the wind pushed them toward the oncoming canoe. Light strung his bow and waited for a brave to stand. As the canoe neared, a brave, reckless in the excitement of the battle, stood and shook his war club. Light's arrow pierced his chest, pushing him back into the river. Without missing a stroke, the paddlers powered the canoe onward. Backs were bent and heads were down.

A sudden puff of wind came from the south, filled the sail and pushed the flatboat along faster and faster into the path of the war canoe. Too late the eager bloodthirsty Indians saw their danger and tried to evade the craft bearing down onkeelboat and lifted his hand before he turned into the woods. He had no weapon; Vega kept them locked up, allowing the crew to carry only their eating knives unless the boat were attacked. Dixon had been so eager for a little time to himself that he had forgotten to ask Julio for a gun or a knife.

The woods were dim, cool and quiet. The wave of waterfowl that had flown up when he approached the bank had settled farther downriver. Well out of sight of the Spaniard's spyglass, Dixon stopped and leaned against the trunk of a towering oak. His boots, stirring the dry leaves, made the only sound. What to do? This was the first time he had been alone since he had signed on to


her throat, fluttering to her very ears, as she slowly drew her mouth from his so that she could look at him.

Eli made a kind of a groaning sound, unable for the moment to do or say anything. He could only look at her. His heated gaze took in her smooth golden skin, sweetly curved mouth and her eyes, large soft brown eyes that looked back at him in puzzlement.

"That was sweet. You're sweet," he said huskily. When she said nothing, he whispered, "I want to kiss you again." She still said nothing, and he lowered his lips to hers again.

Slowly, deliberately, his mouth covered hers, pressing gently at first while he guided her arms up and around his neck, then wrapped her in his. His kiss deepenedAn unlicensed illegal immigrant was “grossly impaired” when he crashed into an ambulance and killed a 3-year-old boy, court papers say.

The boy, from Wise, Va., died Monday, a day after the crash. He was with his mother in an ambulance when it was struck and rolled over in Winston-Salem, N.C. Lyndsay Ann Oakes, 27, suffered minor injuries. The boy was not identified.

Jose Duran Romero, 27, blew a 0.19 on a breathalyzer nearly two hours after the crash, more than twice the legal limit, FOX8 Winston-Salem reported late Monday.

Court papers say Romero, who was behind the wheel of a Honda Accord even though he had never owned a driver’s license, had “bloodshot, glassy eyes,” slurred his speech and looked “grossly impaired,” according to the station.

Romero was also in the


was reported (Figure [7](#Fig7){ref-type="fig"}).Figure 7**Strain value for all the groups at 3, 6 and 9 weeks of treatment.** Data presented as mean ± SEM (p \< 0.05). Sham: sham-operated, OVX: ovariectomized control, ERT: ovariectomized and estrogen supplementation, LP20: ovariectomized with LP supplementation (20 mg/kg), LP100: ovariectomized with LP supplementation (100 mg/kg).

Young modulus {#Sec14}
-------------

The Young Modulus of the Sham group was significantly higher than the OVX group at 9 weeks of treatment. There was a time-dependent increment in the Young modulus value for the Sham and LP-treated groups. At 9 weeks of treatment, both the LP20 and LP100 groups showed significantly higher Young modulus than the Baseline and OVX group (Figure [8](#Fig8){ref-type="fig"}).Figure 8**Young modulus value for all groups after 3, 6 and 9 weeks of treatment.** Data presented as mean ± SEM (p \< 0.05). Sham: sham-operated, OVX: ovariectomized control, ERT: ovariectomized and estrogen supplementation,is disguised as an evil version of Mario, kidnaps Peach. Bowser himself eventually appears in the final boss battle of the game. In New Super Mario Bros., Bowser is the boss of the first world, which features a battle similar to that of Super Mario Bros. After being defeated, he falls into lava and is reduced to a skeleton called Dry Bowser. He is eventually restored by Bowser Jr. and acts as the final world's boss along with his son. In Super Mario Galaxy, Bowser steals the Power Stars from Rosalina's Comet Observatory and kidnaps Peach, taking her to the center of the universe to recreate it, with the intention of taking over the universe. He also appears in New Super Mario Bros. Wii as the final boss


gives players an inside glimpse of his ego and megalomania. IGN editor Craig Harris described Bowser as the only "core Nintendo character over the past couple decades" to not have a starring role in a video game, and this game acts as his "big break". 1UP.com editor Jeremy Parish stated that Bowser makes the game, describing him as more interesting than Bowser's Inside Story predecessor's partners, the baby forms of Mario and Luigi. GamePro editor Alicia Ashby called Bowser one of the most "lovable characters in the Nintendo universe", and praising Bowser's Inside Story'' for giving him "much deserved time in the spotlight". GameSpy editor Phil Theobald called him the breakout star of the game, stating that "the gruff, quick-to-anger pro/antagonist is a treat to watch as heAmanda Knox has returned to the United States wearing the halo of victimhood for a crime she presumably did not commit. But it should not be forgotten that in her long journey toward exculpation, she blamed an innocent black man for the murder for which she was accused.

Diya "Patrick" Lumumba -- a Congolese-born resident of Italy -- owned a bar in Perugia that he named Le Chic. Knox worked there part time. When the Italian police questioned Knox about the murder of her roommate, Meredith Kercher, she implicated Lumumba. He was promptly arrested. And yes, we've seen it all before. Before there was Amanda Knox, there was Charles Stuart.

Knox told Italian police in a written statement that she saw Lumumba enter Kercher's room on the evening of Nov,


it was like she wasn't even listening my cervix shrunk u would think she would do something to try to help me n my baby all she said is too put another stitch in...really??? r u crazy wen the risk of them breaking my water is much higher at 23 weeks i don't see why she cant give me the progesterone wen that seems to help so much ppl and so much less risk. Even after i got my surgery i went to see her she asked if i had discharge i said yes she didn't even check down there a week later i felt something wasn't right went to er found out i had infection which usually left untreated leads to preterm labor ughh..next week i havehome. Well just four days later, I went to the bathroom and saw what looked like my mucus plug and I called my OB who sent me immediately to labor and delivery. I was told that I was dilated a little and that membranes were visible. The doctors put me on magnesium sulfate, gave me steroid shots and antibiotics. The next day I was still on magnesium (worst. drug. Ever!) and I was transferred to a nearby hospital with a better NICU. I was told I was 70% effaced and around 1.5cm dilated. So now I am on hospital bed rest for as long as I can maintain pregnancy. I am off the IV medications and I have shower and bathroom privileges. But that's basically it. I am


them in there. If they are, they face an almost overwhelming chance of death or severe disability. A cerclage would prevent that.

I would suggest asking your Dr. WHY she/he's discouraging it. In my case there is no evidence it helps for twins, and if the membrane is already out, they run the risk of terminating the pregnancy. Find out what about your situation makes him/her say that.

I would also ask about a 2nd opinion. Some dr's don't like cerclage, and some are just clueless. . .and if you don't go to a high-risk obgyn your dr, may not know that much about your situation. But, drs often sound super authoritative even when they don't know. Your insurance should be ok with you switching to a high risk docadvertisements on this Site may collect and use information about your visits to this Site and other websites in order to provide advertisements about goods and services of interest to you. If you would like to obtain more information about these advertising practices and to make choices about online behavioral advertising, please click here


turned out that the family had come just in time: Colton had to have an immediate appendix surgery. However, more desperate moments were in wait, as the boy’s appendix perforated during the surgery, and the routine intervention turned into a resuscitation procedure.

The doctors fought for Colton’s life for a long time; during the resuscitation process, the little one’s condition became critical, and the parents were bracing for the worst. The father locked himself up in a room and started fighting with God, asking why this was allowed to happen.

Colton was taken home 17 days after

The boy didn’t die; in fact, he started healing so quickly that he was allowed to go home in 17 days after the surgery. A few days after he started recollecting what happened to(3), $\Delta N$ (2p-2h) (3’), $\Delta\Delta$ ($\pi N$) (4), $\Delta\Delta$ (2p-2h) (5), $\Delta\Delta$ (3p-3h) (6). The conventions for the various lines drawings are given in the text.*](crsfig1.eps){width="12cm" height="7cm"}

The bare responses are then given by the standard relations: $$\label{eq:3}
R^0(k)(\omega,q) = -\frac{1}{\pi} \, \mathrm{Im}(\Pi^0(k)(\omega,q,q) ),$$ with the obvious sum rule: $$R^0(\omega,q) = -\frac{1}{\pi} \, \mathrm{Im}( \Pi^0(\omega,q,q) ) = \sum_{k=1}^{n_k} R^0(k)(\omega,q),$$ where $ n_k $ denotes the number of partial reaction channels ( $ n_k = 7 $ in our model).

Following the method detailed in ref. [@delorme/guichon; @delorme/guichon/pl] we include the effects of nuclear correlations by exactly solving the RPA equations in the ring approximation. For instance the inclusive RPA polarization propagators $ \Pi(\omega,{\hbox{\boldmath$q$\unboldmath}},{\hbox{\boldmath$q$\unboldmath}}^\prime) $ are solution of the generic equation: $$\label{eq:4}
\Pi = \Pi^0 + \Pi^0 \, V \Pi$$ where $


could be responsible for the small discrepancy between the experimental and simulated events distributions in Super-Kamiokande [^2]. But we need complementary informations to ensure this conclusion. Indeed it is hard to establish the enhancement factor firmly. Our present analysis leads to a maximum enhancement factor of the order of . We have already mentioned that the problem of pion absorption, which is not yet considered in our calculations, could still enhance this factor. We should also be aware that there exists some misidentification problems which could have a more or less large effect. One of the misidentification source, pointed out by the authors of ref. [@kim/schramm/horowitz], is the “coherent” pion production. Their analysis is based on the assumption that the forward peaked angular distribution of the coherent pionsRichard A. Suleski Jr., 35, of Waukesha, died Saturday, June 16, 2007.
Services for Rich are pending for Wednesday, June 20, at St. Mark’s
Evangelical Lutheran Church. For further information, please call the
Cesarz, Charapata & Zinnecker Funeral Home, Cremation and Preplanning
Service at 542-6609 or go to www.waukeshafuneralhome.com.


staff also rose “sharply”, with this led by the nursing, medical and care sector.

February also saw a rise in average pay rates for temporary and contract staff, according to the research.

Finance Secretary John Swinney said: “These figures are welcome and signal continued improvement in Scottish job market conditions. This represents the fortieth consecutive month of improvement and the strongest performance since 2007.

“They illustrate the significant economic progress being made in Scotland, and follow recent labour market figures which show that Scotland is outperforming the UK as a whole in terms of employment, unemployment and inactivity rates.

“Scotland’s economy is continuing to recover, creating more jobs and greater economic opportunities for the people of Scotland.”they can avail from a serving or two of coconut juice. But before we go to the health benefits, it would only be prudent to talk about the contents of coconut juice that help bring about its health benefits.

The nutritive value of coconut juice is made possible by a unique combination of substances that are only “concocted” inside a healthy, green coconut. The resulting coconut juice mixture contains naturally occurring sugars, vitamins and minerals, enzymes, amino acids, and electrolytes among other things.

This unique combination of healthy substances gives birth to the following coconut juice health benefits:

§ The combination of water and sugars in coconut juice make it an ideal thirst-quencher without the harmful effects of excess carbs. In fact, studies have shown that coconut juice has very low


carb content and 99% fat free.

§ Coconut juice is perhaps the cleanest drink around. Unlike potable water that has to undergo various processes just to make it drinkable, good quality coconut juice is sheltered inside the coconut fruit and insulated from the outside world. This is perhaps one of the more understated of the many coconut juice health benefits: that you are drinking something that’s absolutely pure. You can’t say the same for many other “alleged” health drinks.

§ The electrolytes in coconut juice acts much like a naturally-occurring dose of Gatorade minus the sugars. It replenishes the electrolytes you lose from sweat and ensures that your body works as intended from a muscle firing and electrolyte balance standpoint. This makes coconut juice an effective rehydrating agent for patientsIdentification of novel serotonin reuptake inhibitors targeting central and allosteric binding sites: A virtual screening and molecular dynamics simulations study.
The serotonin (5-hydroxytryptamine, 5HT) transporter (SERT) is a member of neurotransmitter sodium symporter (NSS) family, which maintains neurotransmitter by reuptaking 5HT into synapses. Decrease in serotonin concentrations in synaptic clefts have been reported to cause psychological and neurological disorders. Therefore, inhibition of SERT is a potent strategy for the treatment of related diseases such as depression. In this study, approximately 260,000 small molecules from an available chemical database have been virtually screened both at central and allosteric binding sites of SERT to identify potent novel candidate SERT inhibitors. A set of docking algorithms were used to predict binding modes and energies of compounds. Screening analyses led three top-ranked hit


Real Rock

"Real Rock" is an instrumental reggae song by Jamaican band Sound Dimension. It was recorded in 1967 at Jamaica Recording Studio in Kingston, Jamaica, and released as a single in 1968 through Studio One. The song was produced by Clement "Coxsone" Dodd and performed by Eric Frater (guitar), Boris Gardiner (bass), Phil Callender (drums), Denzel Laing (percussion), Vin Gordon (trombone) and Jackie Mittoo (keyboards), who played the riddim's signature three-note Hammond organ figure.

The song is significant for giving rise to perhaps the most popular reggae riddim of all time, having been versioned hundreds of times by artists ranging from The Clash to KRS-One to 311. According to a 2004 The New York Times article, C. Dodd considered the song his crowning achievement.

Partial list of songs using thewe observed^[@CR35]^. While lipids are not typically found in urine, alterations in plasma lipid levels associated with renal failure have long been described^[@CR36]^. Whether specific lipids, such as those identified in the kidney tissues, are altered in the plasma lipid components needs to be explored in greater detail. Regardless, the specific lipid profiles associated with different models of renal injury should be explored using DESI-MS in renal tissues.

UUO resulted in a remarkable increase in the level of a phosphatidylglycerol, PG(22:6/22:6) beginning 1 d after obstruction. The significance of this increase is unknown. We have previously observed significant elevations of PG(22:6/22:6) in an MYC-driven mouse model of renal cell carcinoma that relies on a kidney-specific promoter with a tetracycline responsive element^[@CR19]^ and a mouse lung cancer model where RAS


The invaluable Alec MacGillis, now doing god's work at ProPublica, has an anger-making story about some tenants in Baltimore who appear to be the victims of the worst landlord since Cromwell parceled out Mayo to his soldiers. Here's one example. A woman rented a place in this development and her next door neighbor was more than a little batty.

She began accosting Warren's visitors. She shouted through the walls during the day. And at night she banged on the wall, right where Warren kept the bassinet in which her third child slept, waking him up.

Fed up, the woman decided to move. She gave the proper notice and filled out all the proper paperwork. (She was a client of the federal Section 8 housing program for poorer tenants.) And she"distress-ridden, Class B" apartment complexes: units whose prices fell somewhere in the middle of the market, typically of a certain age and wear, whose owners were in financial difficulty.

And, naturally, there are lesser parasites dining on what the buzzard leaves behind.

The vast majority of these cases have been filed by a single small law firm in the Baltimore suburb of Owings Mills. The law office of Jeffrey Tapper specializes in "collections" work, with an emphasis on landlord-tenant cases. It has represented several other real-estate management companies, including Sawyer, which retains a stake in many of the Kushner complexes. In April, I drove to Owings Mills in hopes of speaking to Tapper. As I waited for him by reception, I overheard an assistant making a call about a new


during a hearing on Godhra did not have evidence to put down that remark in his written judgment.

Amidst the decade-old demonisation of Modi unleashing a ‘Genocide’ against Muslims, nobody has explained why, of the total 1044 killed in those riots, 254 were Hindus.

Modi fielded 247 Muslim candidates on the BJP card in Gujarat’s civic elections of October 2010, and, more unbelievably, 118 of them were victorious. Would a ‘communal’ chief minister do that ‘secular’ act?

Even after Indira Gandhi got the word ‘Secular’ into the Preamble of the Constitution of India with the 42nd Constitution Amendment Act, 1976, our nation is not secular. Take a look below

‘Dr Ambedkar made it clear in Parliament that he did not believe our Constitution was secular because it allowed different treatment to variousCoffeehouse will flee new ballpark

Oriole Park at Camden Yards has helped spawn many new businesses downtown, but it has also played a role in the closing of a more modest neighborhood gathering spot.

The organizer of the Friday night coffeehouse at Old Otterbein United Methodist Church, Sharp and Conway streets, has decided to close the operation and move to Charles Village -- in part because of the new ballpark three blocks away.

The Rev. Douglas Fox, church minister and coordinator of the weekly coffeehouse, said he is shutting it down largely because he fears that the roar of the crowd at the ballpark will drown out the folk music concerts at the coffeehouse. He is also afraid that the traffic congestion and high demand for parking on game nights will


QRS (within frequency band of 80–300 Hz) in patients with Myocardial Infarction comparing to normal subjects.

Research efforts during the 80-90s have shown that myocardial ischemia also induces changes to the depolarization phase and confirmed the use of HFQRS-RMS as a quantitative diagnostic measure of supply myocardial ischemia and demand myocardial (stress-induced) ischemia.

References

Category:Cardiovascular diseases                     M1b
  IVC              Any T                   Any N                      M1c

*Primary tumour (T)*: Tx, primary tumour of unknown; T0, no evidence of primary tumour; Tis, carcinoma *in situ*; T1, tumour invades submucosa; T2, tumour invades muscularis propria; T3, tumour invades through the muscularis propria into the peri colorectal tissues; T4a, tumour invades through the visceral peritoneum; T4b: tumour


directly invades or adheres to other adjacent organs or structures.

*Regional lymph nodes (N)*: Nx, lymph nodes cannot be assessed; N0, no lymph node metastases; N1, 1--3 lymph node involvement; N1a, 1 lymph node; N1b, 2--3 lymph nodes; N1c, non‐nodal tumour deposits without identified lymph node metastases; N2, 4 or more lymph node involvement; N2a: 4--6 lymph nodes; N2b: 7 or more lymph nodes.

*Distant metastasis (M)*: Mx, distant metastasis cannot be assessed; M0, no distant metastasis by imaging; M1, distant metastasis; M1a, metastasis to one organ or site without peritoneal metastasis; M1b, metastasis to two or more organs or sites without peritoneal metastasis; M1c, peritoneal involvement regardless of other organ involvement.

More recent research has, however, suggested that a subset of patients with stage I CRC have lymph node metastasisis another common antineoplastic agent to which there are varying levels of chemo resistance in CRC patients.[30](#jgh312153-bib-0030){ref-type="ref"} The treatment efficacy of this platinum‐based regimen can be modulated by excision repair cross‐complementing group 1 (ERCC1)---one of the ERCC1‐XPF enzyme complexes that play a crucial role in the nucleotide excision and repair (NER) pathway for DNA recombination and DNA repair.[31](#jgh312153-bib-0031){ref-type="ref"} In particular, ERCC1‐C118T (T/T or T/C) polymorphism[32](#jgh312153-bib-0032){ref-type="ref"} or a lower expression of ERCC1[33](#jgh312153-bib-0033){ref-type="ref"} has been reported as being associated with unfavorable prognosis in patients undergoing treatment with oxaliplatin. It has therefore been proposed as a surrogate biomarker for oxaliplatin resistance. However, clinical trials have not demonstrated the predictive ability of ERCC1 in oxaliplatin‐based treatment.[34](#jgh312153-bib-0034){ref-type="ref"} Thus, EMSO has not recommended ERCC1 testing prior to the use of oxaliplatin in routine practice.[23](#jgh312153-bib-0023){ref-type="ref"}

More


                          NCT02331927

\[18F\] FLT‐PET, 3′‐deoxy‐3′‐18F‐fluorothymidine positron emission tomography; mCRC, metastatic colorectal cancer.

VEGF receptor therapies {#jgh312153-sec-0005}
=======================

The VEGF receptor is a transmembrane protein containing a split tyrosine--kinase domain at the intracellular level and seven immunoglobulin‐like domains at extracellular levels for angiogenesis and vasculogenesis.[62](#jgh312153-bib-0062){ref-type="ref"} Overexpression of VEGF results in tumor progression and metastasis as well as lower patient survival rates.[63](#jgh312153-bib-0063){ref-type="ref"}, [64](#jgh312153-bib-0064){ref-type="ref"} Today, three approved biological agents targeting VEGF are available for CRC patients. Ramucirumab targets the VEGF‐A receptor activation by modulating VEGFR‐2; ziv‐aflibercept inhibits placental growth factor (PIGF), VEGF‐A, and VEGF‐B by using its IgG1 Fc‐VEGFR; and bevacizumab blocks VEGF‐A to cause ligand sequestering (Fig. [1](#jgh312153-fig-0001){ref-type="fig"}).[65](#jgh312153-bib-0065){ref-type="ref"} Interestingly,treatment due to patients\' strong desire to have their own children. Future randomized controlled studies are needed to evaluate the efficacy of the present IVA treatment protocol. Future improvements are also needed to improve the efficiency of IVA, including the selection of optimal graft sites and preventing grafting associated follicle loss ([@B27][@B28][@B29]). In addition, new methods are needed to predict the presence of residual follicles in grafts and to estimate the outcome of IVA procedure. Currently, oocyte vitrification has been used in patients with cancer for postoperative fertility treatment ([@B30]). However, this procedure cannot be used in all patients with cancer due to the need for immediate radiation or chemotherapy or complications associated with high estrogen levels caused by ovarian stimulation. Our data showed that, even in patients


Q:

Lots of RegEx match against huge number range (PHP)

I have to check a given amount of regular expressions, which are defining number ranges for dial plans, against an input number range.
The target is to check and see, if any of the numbers in the range are free, or which regular expression matches for the number. Last situation is said to be an occupied number, otherwise if no regex matches, the number is defined as free.
I match every number from the input range against every regexp and generate some output code.
The main problem is, that this sort of "brute force" causes huge load on server and for 50.000 numbers the default php timeout is thrown. Anyhow, this is in my eyes also too long to wait for. The outputit once.
if( ! $matched ) {
    $code = '
' . $number . ' FREI
';
} else {
    $code = '
' . $code . '
';
}

$matched_isdn[] = array( "code" => $code );

As above, it appears that these for loops are redundant. You could probably combine them, similarly to the one showed above. I won't write this one out, as you can extract everything you need from that previous example and apply it here.
That appears to be it for your inefficiencies. If the program is still running too slow, it is probably because you have a double loop and that internal loop is probably rather large. I can't think of any way around this, however. You have to loop over these arrays for each


input. But even then, people make mistakes, so basic validation wouldn't hurt.
It appears that you are working with classes and OOP. In order to be effective with it, you should brush up on key OOP principles, such as the DRY principle I mentioned. There's also SOLID. Google those and you should get a whole bunch more to work with. You don't have to understand all of them right away. Just reading it so that you are aware of it is enough at first. Then, subconsciously you will be able to start looking at your code differently and can then start trying to apply these principles.
I hope this helps!

were considered the control group, did not use TEACCH or LEAP methods, and were a mixture of inclusive and self-contained classrooms. The teachers were offered "refresher" instruction to maintain fidelity of how the LEAP and TEACCH interventions were implemented, and researchers controlled for fidelity of the interventions to ensure they were being delivered appropriately. Students were assessed on a number of measures that included cognitive, behavioral, psychological, and social skills at the beginning and end of the school year. All data were obtained at least 6 months apart, across three data sources (parent report, teacher report and student performance).

Investigators assembled the test measures into seven composite variables that were grouped based on the features and outcomes being rated and statistical correlation between student's scores on each individual measure.


with ASD to social rejection from typically developing peers. Researchers in this study thus sought to comparatively examine the impact of community-based early intervention. They reviewed the preschool educational records of 98 preschool aged children with ASD placed in one of three settings: inclusive classrooms (with typically developing peers), mixed disability classrooms, and autism-only classrooms. Children in inclusive groups received intervention services (typically 3 hours a day, 3 days a week) from early childhood or special education teachers in classrooms for typically developing children. Children in mixed disability classrooms in center-based preschools received early intervention (typically 2-3 hours a day, 3 days a week) from early childhood or special education teachers in classrooms with children with developmental or other disabilities. Children in autism-only groups received early intervention inface recognition, and language. This suggests that their ASD symptoms really had improved to the point that their ASD diagnosis had been appropriately dropped. To better understand how this group differs from others with ASD, the researchers used patient histories, including previous test scores and clinical descriptions, to examine the early childhoods of the OO children, comparing their behavior to that of children with 'high-functioning' ASD. Upon examination, researchers found that earlier on in life, OO children generally had milder social deficits and slightly higher IQs compared to those with 'high-functioning' ASD, but had equally severe difficulties with communication and repetitive behaviors. Although it is possible that deficits in more subtle aspects of social interaction or cognition still remain in these individuals, the results do substantiate reports of


achievements. Tell me why they matter! This paper will probably be close to 1 ½ to 2 pages. Don’t plagiarize by copying from an outside source. Think about our discussion, look at your notes, and if you haven’t read pages 42-45, read!!!! Staple this page to your paper and turn in on October 12, 2017.

Content (25 points) - each empire is clearly identified and evaluated

Punctuation and grammar (5 points)

Spelling (5 points)

Typed 12 point font Times New Roman or Calibri OR written in blue or black ink (3 points)

This paper is stapled to your essay. (2 points)

40 points possible

Oct 9 - read pages 43-46. Make a 4-part chart in your notebook and add details about time periods, achievements, and important people to the following four sections: Babylon (p. 43),that on that day he opened a book by Pushkin and suddenly became
fascinated with one phrase: “Guest were arriving at the dacha” («Гости съезжались на дачу...»).

In the evening he brought a
sheet of paper bearing the famous words “Everything had gone wrong in the Oblonsky household.”

And those with an advanced knowledge
of Russian can watch an online “live” version of the novel, based on an online
reading marathon in October 2014 that was watched in more than 106 countries.
Unfortunately it has only Russian subtitles, but we think this will encourage
you to learn the Russian language.

March 30 is notable for yet
another historical event which RBTH can’t ignore – this day 148 years ago the
Russian Empire sold Alaska to the United States.
On March 30, 1867, in
Washington, D.C., the parties signed the agreement to


average word and sentence length in the works of Thomas Babington Macaulay, HG Wells, and GK Chesterton:

Williams, CB. A note on the statistical analysis of sentence-length
  as a criterion of literary style. Biometrika (1940), 31, 356-361.
Yule, GU. On sentence-length as a statistical characteristic of style
  in prose: with applications to two cases of disputed authorship.
  Biometrika (1939), 30, 363-390.

Thomas Babington Macaulay: mean sentence length 22.07 words, variance
230.22
HG Wells: mean 24.08,  variance 199.38
GK Chesterton: mean 25.91, variance 131.05

a shuttle bus to the nearby Moss Airport, Rygge.

Services

Passenger train services are provided by the Norwegian State Railways (NSB). The L2 service calls at all stations between Oslo S and Ski. The L21 and L22 services make one stop between Oslo and Ski, then L21 continues onward on the Western Line calling at Ås, Vestby, Sonsveien and Kambo before terminating at Moss. L22 runs along the Eastern Line, calling at six stations before Mysen. R20 only stops at Ski before Moss, then serves Rygge, Råde, Fredrikstad, Sarpsborg and Halden. In regular hours L2 operates with two hourly services, while the others operate with one hourly services. There are additional rush-hour trains. Three R20-services continue onward to Gothenburg Central Station each day.

Architecture

Peter Andreas Blix was hired as the national


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ASUS Eee box and ACER Revo work out there issue with Drivers and see where it takes it..When I deliver this one to the nice dirty marina I'm thinking about getting one of these for the 40 inch Insignia TV and one to connect to the TV.. The object is really to be able to bring down the Electric Costs over all and still be able to surf get email and work.. with an occasional movie

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Be a Organ Donor. A chance at life. This site never spams or sells its list to anyone. No pop up's or scamsAn inconvenience, but if you want to make omelettes, you have to break some eggs.

I'VE been waiting one of those ee pcs for a while money is to tight here though.the case with segmental extension of the tumour had local recurrence, which was treated successfully using cryotherapy (with negative endobronchial biopsies since), and no cases of metastatic spread occurred. One patient, in whom the histopathological diagnosis was changed from typical to atypical carcinoid following resection, went on to have a surgical bilobectomy 3 months later. Extensive fibrosis was noted at the site of original tumour resection with no evidence of residual disease. Bronchial artery embolization prior to endobronchial resection of centrally located carcinoids is feasible and safe. The reduction in bleeding may facilitate and simplify the procedure. The possible application of this combined therapy to the management of atypical carcinoids warrants the design of a larger prospective clinical trial.


Diabetes mellitus, an increasingly common disease, can cause diabetic nephropathy (DN) and diabetic cardiomyopathy (DCM), leading often to the need for dialysis and kidney transplantation, and to heart failure or stroke. Current knowledge of genes associated with an increased risk for diabetic complications is very limited. Diabetic complications at present are treated by intense glycemic control and management of end organ damages; specific treatment is lacking. Developing and studying mouse models of diabetes that recapitulate the complications seen in the later stages of human diabetes is a powerful approach to enhance our knowledge of genetic risk factors and can contribute to developing preventive and therapeutic measures. During the past grant period we modified several genes expected to affect blood pressure or cardiac/kidney function to obtain a low expressingIntegrated Resources, 850 F.Supp. at 1118; Griffin v. McNiff, 744 F.Supp. 1237, 1255 (S.D.N.Y.1990), aff'd, 996 F.2d 303 (2d Cir. 1993). "The time from which the statute of limitations begins to run is not the time at which a plaintiff becomes aware of all of the various aspects of the alleged fraud, but rather the statute runs from the time at which the plaintiff should have discovered the general fraudulent scheme." Dolan v. Rothschild Reserve Int'l, Inc., 1991 WL 155770, at *2 (S.D.N.Y. Aug. 6, 1991) (quoting Klein v. Bower, 421 F.2d 338, 343 (2d Cir.1970)).
To determine when the plaintiff should have discovered the scheme requires a two part inquiry: first, whether the plaintiffs received information sufficient to alert a reasonable person to the probability that they had


Mem.Opp'n Defs.' Mot.Dismiss at 15), without alleging how any of the aspects of the defendants' misrepresentations obscured their fraud notwithstanding all the information the plaintiffs concededly possessed. Second, the plaintiffs assert that the defendants took affirmative steps to conceal their fraud, specifically that they aligned themselves with the investors and controlled the lawsuits filed against the venture's management, keeping the plaintiffs in the dark. (See Compl. ¶¶ 40-45.) The plaintiffs do not elaborate, however, or explain what steps either defendant took to manipulate the lawsuits or frustrate the plaintiffs' efforts to discover the defendants' role in the fraud. In short, neither of the plaintiffs allegations of wrongful concealment are pleaded with sufficient particularity under Rule 9(b).
Moreover, with respect to the second element of fraudulent concealment, the plaintiffs failalleged.
The plaintiffs further argue that they were under no duty to exercise due diligence because the defendants were their accountants and owed the plaintiffs a duty to disclose the fraud to them. Whatever duties the defendants owed to the plaintiffs, compare Greenblatt v. Richard Potasky Jewelers, No. 93 Civ. 3652, 1994 WL 9754, at *4 (S.D.N.Y. Jan. 13, 1994) (citing Fund of Funds, Ltd. v. Arthur Andersen & Co., 545 F.Supp. 1314, 1356 (S.D.N.Y.1982) ("Courts do not generally regard the accountant-client relationship as a fiduciary one.")); Mishkin v. Peat, Marwick, Mitchell & Co., 658 F.Supp. 271, 273 & n. 10 (S.D.N.Y.1987) (Weinfeld, J.) (citing Fund of Funds), their alleged failure to disclose facts would not excuse the plaintiffs' lack of diligence in investigating the facts of which they


concealment, including their own due diligence, and cannot toll the statute of limitations. At the latest, the plaintiffs should have known of the alleged fraud in connection with their investments by February 1990. Since this lawsuit was filed more than four years after that time, the statute has run and both RICO claims are time barred. The Complaint is therefore dismissed pursuant to Fed.R.Civ.P. 12(b)(6).[1]
Because this dismissal is based on the plaintiffs' failure to set forth specific facts to support the elements of fraudulent concealment, a failure to plead with particularity under Fed.R.Civ.P. 9(b), the Complaint is dismissed without prejudice to the plaintiffs' filing an amended complaint alleging fraudulent concealment, including the element of due diligence, with sufficient particularity. See Luce v. Edelstein, 802 F.2d 49, 52 (2d1995 WL 46691, at *6; see Landy v. Mitchell Petroleum Technology Corp., 734 F.Supp. 608, 622 (S.D.N.Y.1990) (citing Hecht v. Commerce Clearing House, Inc., 897 F.2d 21, 26 n. 4 (2d Cir.1990)). To comply with Rule 9(b), the complaint must allege specifically when and where the misrepresentations took place, the content of those misrepresentations, and the identity of the person or persons making them. See Mills v. Polar Molecular Corp., 12 F.3d 1170, 1175 (2d Cir.1993); Ross v. Bolton, 904 F.2d 819, 823 (2d Cir.1990); Wexner v. First Manhattan Co., 902 F.2d 169, 172 (2d Cir.1990). The plaintiff must also explain how the misrepresentations were fraudulent. See Cosmas v. Hassett, 886 F.2d 8, 11 (2d Cir.1989); Baxter v. A.R. Baron & Co., Inc., No. 94 Civ. 3913, 1995


1$: the projection onto this summand from $U(2^n)$ is obtained by simply sending $x$ to its residue modulo $4$.

A:

There is something general. The Chinese remainder theorem says that if the prime factorisation of $n$ is
$$n = \prod_{k=1}^r p_k^{m_k},$$
then we have a ring isomorphism
$$\phi \colon \mathbb{Z}/(n) \to \prod_{k=1}^r \mathbb{Z}/(p_k^{m_k}),$$
so in particular the group of units modulo $n$ is the direct product of the groups of units modulo the prime powers dividing $n$,
$$U_n \cong \prod_{k=1}^r U_{p_k^{m_k}}.$$
So it remains to find the structure of $U_{p^m}$ for prime powers. For odd primes, the group of units is cyclic, of order $\varphi(p^m) = (p-1)p^{m-1}$, and for $p = 2$ we have $U_{2^m} \cong \mathbb{Z}/(2)\times \mathbb{Z}/(2^{m-2})$ when $m \geqslant 2$ (and $U_2 = \{1\}$).
I don't know how one could see that $U_{p^m}$ has thehouse edge below 0.93%.

Eliot Jacobson has published a simple hole-carding strategy that yields from +7.6% to +62.7% depending on which board card you see. Pala procedure places the bottom board card on 4th St, so I guess it’s only worth +7.6% when you see it.

GL @ Pauma tonight. I’m not driving any more this weekend 😦 I won $90 at Raise It Up last night, with all the profits coming from 3x raising 467d. The dealer (John) said I didn’t have a winning hand yet it, but was otherwise ok with my raise. (I hate it when dealers strongly disapprove of basic strategy.) He turns up 3d on 4th St, and I have a straight flush draw! He turns up Ad on 5th St, and I have a


beyond review by an appellate court. As noted in State v. Beavers, 364 So.2d 1004, 1009 (La.1978), Louisiana does not subscribe to special verdicts and otherwise follows the rule at common law that jurors generally may not testify with regard to their mental processes in connection with their verdict. See Tanner v. United States, 483 U.S. 107, 117, 107 S.Ct. 2739, 2745-46, 97 L.Ed.2d 90 (1987), now codified in LSA-C.E. art. 606(B). See also, State v. Abney, 347 So.2d 498, 502 (La. 1977), decided under the former La. R.S. 15:470, which was the precursor of LSA-C.E. art. 606(B). The focus of the inquiry under Jackson thus necessarily remains on "not whether this jury should have found the evidence sufficient, but whether any jury could have done so." Unitedfelony record provided a reliable basis in Louisiana law for the court, as well as any rational fact finder, to discount Defendant's exculpatory testimony. See LSA-C.E. art. 609.1(A), which governs attacks on a witness's general credibility ("In a criminal case, every witness by testifying subjects himself to examination relative to his criminal convictions."); State v. Sweeney, 443 So.2d 522, 529 (La.1983)("Irrespective of its relevance to the present prosecution, a conviction per se historically is a relevant factor for the trier of fact's evaluation of a witness' credibility."). Overall, as the judge observed and as any rational fact finder might also conclude, the evidence presented at trial provided no articulable reason for doubting the credibility of Officer Paxton's testimony, parts of which were corroborated by Defendant's own account, as


a basis for finding Defendant guilty as charged.
Absent internal contradiction or irreconcilable conflict with the physical evidence, a single witness's testimony, if believed by the fact finder, is sufficient to support a factual conclusion. State v. Legrand, 864 So.2d 89, 94 (La.2003). Credibility determinations are within the sound discretion of the trier of fact and will not be disturbed unless clearly contrary to the evidence. State v. Vessell, 450 So.2d 938, 943 (La.1984).
Although some discrepancy exists as to who approached which side of the car, both officers testified that they stopped Defendant because his taillights were off at 9:00 p.m. There was no evidence to contradict this fact. Both officers controverted Defendant's testimony that he was driving with a passenger. Also, the discovery of cocaine in the carthe trial judge's verdict even though there was sufficient evidence to convict Defendant. Credibility calls are within the fact finder's discretion and will not be disturbed unless clearly contrary to the evidence. State v. Vessell, 450 So.2d at 943. Accordingly, the court of appeal erred by reversing Defendant's conviction and sentence based on insufficient evidence. The judgment of the court of appeal is therefore reversed, Defendant's conviction and sentence are reinstated, and this case is *370 remanded to the district court for purposes of execution of sentence.[5]
REVERSED AND REMANDED.
JOHNSON, J., dissents and assigns reasons.
I respectfully dissent.
In this case, the trial court essentially had to make two credibility determinations. One centered around whether defendant Keith Marshall was alone in the vehicle, as testified to by the two arresting Police


work and listed the defendant by the name of Gregory Marshall, and not Keith Marshall, on the citation and the booking sheet. I agree with the appellate court that the conclusion reached by the trial court that the defendant was untruthful, and his testimony was not credible, based on the fact that he provided an alias to the police officers, was unreasonable in light of the trial court's decision to discredit the testimony of Officer Barre'. After making a credibility determination to disregard Officer Barre's testimony, the court could not rationally utilize the same testimony to discredit the defendant. I would affirm the reversal of the defendant's conviction and sentence.
The standard for appellate review of the sufficiency of the evidence is whether, after viewing the evidence in thestructured into different time periods (pre, season, post, off, etc.).

Through the utilization of the nine governing principles, acute variables, and the five phases of the OPT Model we can ensure our clients expectations are met in a systematic, progressive, and time efficient manner.


methane emissions are related to natural gas extraction and coal mining.

But this is only half of the story as the study did not determine the source of the remaining 50 percent of emissions. Given the more than 20,000 (mainly older) gas wells, myriad storage tanks, thousands of miles of pipelines and several gas processing plants in the area, NASA’s finding that the oil and gas industry is primarily responsible for the “hot spot” is not surprising. In fact, the researchers found only one large source of methane not related to oil and gas operations: venting from the San Juan coal mine. This discovery renders attempts to point the finger at other potential emissions sources, like coal outcrops and landfills, definitively refuted.

Today’s Republicans do nothing by definition. Most ofis serving as the Assistant Secretary of Land and Minerals Management. In this role, Balash oversees the Bureau of Land Management, Bureau of Ocean Energy Management, Bureau of Safety and Environmental Enforcement and the Office of Surface Mining Reclamation and Enforcement, and heads “Interior’s management of all federal lands and waters, and their associated mineral and non-mineral resources, as well as the appropriate regulation of surface coal mining.” See https://departmentofinfluence.org/person/joseph-joe-balash/ for special Interests, previous employers and political connections.
The agency is expected to publish the proposal in the Federal Register, which will kick off a 60-day public comment period. A final repeal of the rule would come after that.
NASA: https://eoimages.gsfc.nasa.gov/images/imagerecords/91000/91564/methane_plot_2016.png


using an AWG is basically of a fixed wavelength type configuration in which the wavelength of the optical signal to be added or dropped cannot be freely selected. Hence, this is only applicable to fixed networks, and is difficult to be applied to networks where expansion or modification of the optical line is frequently carried out. Therefore, there is also proposed an optical add/drop device where the wavelength is selectable by combining an AWG and an optical switch. However, in such an optical add/drop device where an AWG and an optical switch are combined, there is the disadvantage in that construction becomes complex resulting in higher cost.
On the other hand, in the conventional optical add/drop device using the AOTF, the construction is simple giving a low cost. Thisdevice having such a characteristic, there is a problem of the likelihood of an increase in line errors and the like.
To solve the problem attributable to the above AOTF filter characteristics, there is proposed in the article a technique for flattening the AOTF filter characteristics; Janet L. Jackel et al., xe2x80x9cA Passband-flattened Acousto-optic Filterxe2x80x9d, IEEE Photonics Technology Letters, Vol. 7 No. 3, pp 318-320 1995. In the technique described in this article, for a directional coupling type AOTF, in intensity function of a surface acoustic wave (hereunder SAW) capable of flattening the filter characteristics is predicted based on an approximation by combining two half-period sine waves, and a SAW drive method is proposed in accordance with this intensity function.
However, in the above-mentioned conventional technique, there is a disadvantage


the thyroid. I had no energy, and I found it more and more difficult to maintain a healthy weight. That’s when I decided to quit sugar, grains, and processed foods, and to start following a whole-foods-based ketogenic approach to food. More posts by Martina Slajerova Martina Slajerovaa predictive parameter for coronary disease onset, it can also predict the effectiveness of a treatment given to patients with cardiovascular disease. One study followed a group of hypertensive women with no significant heart disease.[@b23-rmmj-4-2-e0014] All women received the same arterial hypertension treatment. After 6 months of treatment they underwent an endothelial function test. Both groups had a similar reduction in blood pressure. The group of women whose endothelial function improved had half as many cardiovascular events compared to those women who showed no improvement in endothelial function.[@b23-rmmj-4-2-e0014] In another study, patients with significant coronary diseases were treated with optimal medical therapy and given standard medications prescribed for their disease.[@b24-rmmj-4-2-e0014] At follow-up visits, the patients underwent endothelial function tests, and improvement was seen in 50% of the patients.


as statins and beta-blockers. The study concluded that the trial showed little difference between invasive interventions (PCI) and medical interventions. However, no test was run to differentiate between the different types of plaque.

A subsequent study examined the COURAGE results and measured the fractional flow reserve (FFR) to differentiate between coronary lesions causing ischemia, and blockages not causing ischemia.[@b27-rmmj-4-2-e0014] The study showed that patients with ischemic blockages who were treated with surgical intervention had a long-term significant improvement in comparison with those who were only given medical intervention. In another multicenter study, patients with multi-vessel coronary artery diseases who underwent invasive interventions (PCI) with drug-eluting stents that were guided by FFR results had a significant reduction in the rate of the composite end-point of death, myocardial infarction, and targetyeah, we loved
him from there.
ALAN SEALES: Yeah,
he's wonderful.
I was telling you backstage
that my friends on Facebook were
like-- they had this whole
thread about how great "Barry"
is, the show, and how
much they love NoHo Hank--
Anthony.
But in the scenes, you're often
looking down or looking away
because he's making you laugh.
BILL HADER: Well, yeah.
If anybody's seen
episode 6 this season,
there's a scene where he
yells at an accordion player.
If you watch, I'm going like--
I'm fully turning away
because, yeah, he's--
every time he would yell, he
would say something different.
You just-- you just
whipped out your accordion
and just fucked this moment.
[LAUGHTER]
And I started laughing because
if you saw last episode that
followed it, that leads them--
I started laughing, and he's
like why are you laughing?
I go because this leads
you to be put on a bus
and almost set on
fire this moment.
[LAUGHTER]
Because you were,


he's like--
looks like Jon Hamm.
He's like a crazy
gorgeous-looking guy.
Our casting director,
Sherry Thomas,
was like I think we should
have him be a series regular.
[LAUGHTER]
I think we need him to come
into my office every day
and read with everybody.
And so I said--
and so I just talked
about the character,
and initially he was
this kind of uptight guy.
And I said, can you
put on some weight?
And he was like I can put
on 20 pounds in two weeks.
And I was like, all right.
You're still going to be you.
You're still going
to look like you.
So he told me a
lot of those guys,
you know, they compete, and then
they make a lot of their money,
and then they retire.
And they're in such
pain that they get--
they take a lot of pills and
they smoke weed and drink
a lot because of all the pain.
And Isaw you on Google.
You're fucking dead, man.
Get out and fucking
say it to my face.
(NORMAL VOICE) Now that he--
and then, yeah, I did that.
And then I did--
and then I was a PA and
I did stuff I like that.
And I started classes
at Second City LA,
and then Megan Mulally
saw me in a show
and recommended me
to Lorne Michaels.
And I got onto "Saturday
Night Live" totally fluky.
Like, just-- yeah.
I don't know how--
I owe my whole
career to her, Yeah.
ALAN SEALES: Wow, and
your whole audition
was impersonations for
the most part, right?
BILL HADER: Yeah, yeah,
yeah, all impersonations.
I did them as a character
I do on the show.
I used to do this Italian talk
show hosts, Vinny Vedecci,
and so it was him
doing impressions.
[LAUGHTER]
Yeah.
ALAN SEALES: Do you
have a favorite one?
BILL HADER: From that?
ALAN SEALES: Yeah.
BILL HADER: They were all like--
you know, it


normal,
but he would say, like, how
much does your brain weigh?
Like he was-- he just wasn't
he clearly wasn't from Earth.
And then I heard with John
Mulaney was, like, yeah,
what if did you just like
grunted or something?
What if it was more
like a character.
I was like, oh--
[GARBLES]
--kind of thing?
I'm just, like, yeah, yeah,
yeah, yeah, yeah, yeah.
Let's do that.
[LAUGHTER]
I mean, I wish I had a
better story, but there was--
it was just John going,
like, doing other noise.
[LAUGHTER]
ALAN SEALES: Well of course,
I think everyone's favorite's
probably Stefon.
And you would crack a
lot because the writer--
was it the writers?
BILL HADER: Yeah, John.
John Mulaney, yeah.
ALAN SEALES: Swap
out the cue cards.
BILL HADER: John would sometimes
tell me as I was walking out,
or he would put
little things on.
It was like one little
thing was off that I--
and then that would set me
off, orthat you're
not being Bill Hader in "Barry"
as opposed to being Barry?
BILL HADER: Well,
I try not to be
myself and in hardly anything,
because that's just boring.
But you're right, though.
I mean, it's funny.
After "Superbad" came out,
it was like, the amount
of crazy authority figures.
And I did a movie
called "Adventureland"
after that, which was like,
Kristen Wiig and I were
the bosses of Jesse
Eisenberg's character.
And that was Greg Mottola,
and I love that movie,
but I just kept getting
kind of cast in--
you know, like I was always
the boss to the main character.
Like, the wacky whatever.
And so honestly, I was like,
I need to learn to write.
I need to learn--
Judd Apatow, when I met him,
he was like, learn to write.
You're going to write
a lot of bad scripts.
Learn to write right now
and control your destiny.
And so I did, and I wrote
a


it in your hand,
like, oh, that's what
frustration looks like.
And then it kind of goes, bloop.
Like that.
For me it really works,
because it's the narrative.
You know, I'm frustrated
because I can't kill Anthony.
I can't kill NoHo Hank.
[LAUGHS]
But you know, that somehow has
helped me, but it's a process.
And it's like, you never
feel like it's an endgame.
You never go, I got it licked.
You just have to
know, it's like, oh,
this is the new thing.
AUDIENCE: Thank you.
I'm going to try to apply
that right now, because I just
asked you a question.
BILL HADER: Oh, please do.
Yeah.
Oh good.
ALAN SEALES: Thank you.
Yeah?
AUDIENCE: Hi.
So I have a kind
of weird question.
Back in December 2012 on
"SNL," Jamie Foxx was the host,
Ne-Yo was the musical performer.
I saw it, and I kind of
had a conversation with you
in front of the studio audience.
BILLY HADER: Wasif you could maybe
talk about one of those
"SNL" skits that never aired.
BILL HADER: Never aired?
Oh man, there's
too many of them.
AUDIENCE: One of your favorites.
BILL HADER: Oh man.
There's one called "The Kasems."
Me and John Mulaney wrote this
one where it was Casey Kasem,
and Dana Carvey was hosting.
It was Casey Kasem coming out
of his house late at night,
and he hears something.
And he's in a robe, and
he goes, who's that?
I'm Casey Kasem.
[LAUGHTER]
And then, I come out from
behind the trashcans.
I go, dad, it's not a
burglar or a raccoon.
It's me, your son, JC Kasem.
And he goes, son,
get out of here.
Dad, hear me out.
Son, I want nothing
to do with you.
[LAUGHTER]
And then they had this
very serious conversation,
but we were talking that way.
So there's lines like--
it was the hardest
John Mulaney and I ever
laughed writing something.
One of the


I said,
did you ever do the thing
where he was a SWAT
guy that he always
tried to get on, who was
this really like SWAT dude.
And he was on a
date with Megan Fox,
I think he said he wrote it for.
And this might have made it
on, where he was this guy,
and she's like, so
you're a SWAT guy?
So what do you do?
And he's like,
[DELICATE VOICE] yeah,
I've been working in SWAT.
[LAUGHTER]
And then it quickly got
into how he raised lambs.
He goes, I raise
lambs on my farm.
It's a really nice time, when
I'm not in the SWAT business.
And the line that
made me laugh was,
she goes, how do
you make your money?
And he goes, well
I sell their hides
and I sell the meat
and all that stuff.
And she goes, so you have
to slaughter the lambs
and he goes, it's really hard.
[LAUGHTER]
I rememberwith both its proximal and distal attachments for the rest of the ligamentType 5Three fascicles or less. A ligament with no separations or gaps within its structure. It may or may not possess a fascicular arrangement

**Pathomechanism of the impingement syndrome** {#Sec3}
==============================================

It should be stressed that most studies were carried out in vitro and do not take muscular tonus and the effects of weightbearing into consideration, we performed a review of the pathomechanism of the impingement syndrome caused by the distal fascicle of the AITFL.

Bassett et al. correlated the presence of this accessory ligament with pain from impingement in the anterolateral aspect of the ankle in patients with a history of inversion sprains \[[@CR4]\]. They postulated that the post-traumatic anterolateral hyperlaxity, due to an injured ATFL, resulted in anterior extrusion


a distally inserting fascicle on the fibula, close to the origin of the ATFL on the fibula. This finding may be missed if the distraction is preserved throughout the procedure \[[@CR2], [@CR24]\]. For this reason, temporarily relieving distraction is advised, when a distal fascicle is seen during arthroscopy \[[@CR2], [@CR22]\]. Fig. 2There is contact between the distal fascicle of AITFL and the talus in dorsiflexion with bending of this fascicle

Only three studies reported on the results of the treatment of AITFL impingement \[[@CR1], [@CR4], [@CR12]\]. Akseki et al. \[[@CR1]\] arthroscopically resected the distal fascicle of the AITFL in 21 patients with chronic ankle pain after an ankle sprain. During the procedure an impinging distal fascicle of the AITFL was found in all cases. Following anterolateral synovectomie, the fascicle was excised.the producers and the well paid cast decided to wrap up Ted's very detailed story to his children.While performing slightly better than Hostages, which it replaced on Mondays, Intelligence was still was way below par for the hits on CBS.NBC's latest attempt to reboot an old hit (see Bionic Woman, Knight Rider... or don't, since they didn't make it either) was a dud, despite the presence of the charismatic Blair Underwood.The promos touted the involvement of Sofia Vergara as executive producer, but few tuned in to this story of a Texas Ranger, played by BSG's Tricia Helfer. Here's hoping Helfer can find the right project for her down the line.The show to have the unwanted "honor" of becoming the first cancellation of the fall was this ABC remake


this attempt to blend a sci-fi story with a Romeo & Juliet type romance failed to resonate.While Suburgatory's fate was precarious last year, things were looking better for the show this season for a little while... Only for ABC to decide to end the comedy after three seasons.There was a lot of disappointment over this series, which took such a notable rising star in Rebel Wilson and failed to capitalize on her appeal.Airing after American Idol would once have been a huge deal, but with that series showing its age -- in the form of much lower ratings -- FOX didn't do this new Bill Lawrence-produced comedy a lot of favors airing it after Idol on Thursdays at 9:30. Though it had its fans, the 90s-set comedy cameRM55, and RM168) on rice chromosome 3 were candidate markers linking to the target *Pi* gene, exclusively, in the F~2~ population. The first round of linkage analysis with 750 viable F~2~ plants revealed that there were 64 and 37 recombinants, respectively, at RM487 and RM16 loci on the centromere side, 35 and 22 distinct recombinants, respectively, at RM168 and RM55 loci on the telomere side, indicating that the four candidate markers were indeed linkage markers with the target *Pi* gene (Fig. [2a](#Fig2){ref-type="fig"}). Because no major *Pi* gene had been previously identified in this region, the novel *Pi* gene in AS20-1 was designated as *pi66*(t).Fig. 2The genomic location of *pi66*(t). **a** Physical maps of the *pi66* region based on the reference sequences of cvs 93--11 and Nipponbare. The numbers shown


Quiz: Howstuffworks

Can You Get 29/35 on This American Football Knowledge Quiz?

Gavin Thagard

Image: cmannphoto / E+ / Getty Images

About This Quiz

"Perfection is not attainable. But if we chase perfection, we can catch excellence." - Vince Lombardi

Lombardi's words still ring true today, and there's no aspect of football where perfection can be reached. If you work hard enough, though, you can get close. Here's your chance to chase perfection off the gridiron by acing this football knowledge quiz. Do you have what it takes, or will you crumble beneath the pressure?

Football has changed a lot since its formation. After all, there was a point where forward passes weren't even allowed. But each new generation has seen both rule changes as well as revolutions within the framework already in place. Theseback

To get better field position

To get three points

To run the clock out

Down 10-6 during Super Bowl XLIV, the New Orleans Saints tried a risky play coming out for the second half where they went for an onside kick to start the third quarter. They recovered the ball and took the lead, eventually winning the game 31-17.

groveb / E+ / Getty Images

A linebacker is sent after the quarterback on which type of play?

Cover three

Press coverage

Spy

Blitz

Throughout his NFL career with the New York Giants, Lawrence Taylor was one of the most feared linebackers in the game. His specialty was the blitz, where he dominated opposing offenses that never knew where he was coming from.

Wiki Commons by Torsten Bolten, AFpix.de

How many points is a field goal worth?

One

Two

Three

Four

Matt Prater holds the NFL


E+ / Getty Images

Where on the field is an extra point kicked from in the NFL?

Three-yard line

15-yard line

20-yard line

25-yard line

Prior to the 2015 season, the NFL moved the extra point from the two-yard line to the 15-yard line to make the play more difficult for kickers. The decision has paid off, and many NFL teams are electing to go for the two-point conversion rather than kick the extra point.

Wiki Commons by Randy Levine

What's the name of the formation where the quarterback lines up a few yards behind the center?

I formation

Ace formation

Shotgun formation

Veer formation

The shotgun formation was once only used in critical passing situations to give the quarterback a better view of the defense. As the passing game became more of a premium, teams began to utilize the formationThe Italian government has declared the region of Lombardia and 14 provinces in northern Italy as quarantine zone, where people are forbidden to travel unless they receive special permission, the Medical Association of Malta (MAM) said in a statement, arguing that flights from the region should be stopped.

"This was ordered because the situation in Italy is very grave with the epidemic spreading like wildfire to thousands, with hundreds of deaths and intensive care admissions. Italy is moving to the situation already seen in china where the only remedy was complete lockdown."

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"It is clear that the Italian authorities just like china have failed to stop the epidemic with their soft approach and have now changed to lockdown approach. The World Health Organisation's failure to recommend travel bans has resulted


and is defined as the sum of the branch length of all edges with descendent tips. This is a new way to characterize the phylogenetic structure of the metacommunity tree, which we term the Edge-length Abundance Distribution (EAD). We give a description in [Figure 2](#pcbi-1002832-g002){ref-type="fig"}. We also provide an analytical method to compute the variance in sampled PD, discussed in further detail in the Supplementary Information.

![The Edge-length Abundance Distribution, , for a community with four individuals.\
All edges are labeled by their length, and the table shows the total edge-length summed across all edges with a given number of upstream tips. Number of tips appears in the left column, and the total edge-length associated with that number of tips, , is shown in the right column. For example, thecircled edge has length two, and has two tips downstream, and therefore contributes length to .](pcbi.1002832.g002){#pcbi-1002832-g002}

The EAD plays an identical role in our sampling framework to the Species Abundance Distribution (SAD) in taxonomic sampling theory [@pcbi.1002832-Plotkin1], [@pcbi.1002832-Green1]. But what does this distribution look like? For the human microbiome we give several examples of the EAD across different subjects and habitats in [Figure 3](#pcbi-1002832-g003){ref-type="fig"} and find that the distribution displays approximately power law behavior. The Species Abundance Distribution has been proposed to take a near-universal log-normal form in microbial communities [@pcbi.1002832-Curtis1], and our preliminary results suggest that a power-law distribution may be its phylogenetic analogue.

![The Edge-length Abundance Distribution (EAD) follows an approximately power-law distribution.\
Here we compute the EAD for trees inferred from 16S bacterial microbiome sequences using FastTree [@pcbi.1002832-Price1],


. The resulting expected PD for Binomial sampling is close to a power law as a function of number of tips sampled, with . We show the corresponding result for Poisson sampling, representing sampling with replacement which is identical to the binomial result until sample size becomes large. Finally, we show two negative binomial schemes with different clustering parameters, , (see Supplementary Information). These parameters are consistent with different degrees of phylogenetic clustering, which leads in general to smaller sampled PD for a given number of tips.](pcbi.1002832.g004){#pcbi-1002832-g004}

For binomial samples from a power-law EAD, we observe a power-law increase in expected PD with sample size, consistent with the power-law increase in expected PD with sample size observed in other kinds of community [@pcbi.1002832-Morlon1], [@pcbi.1002832-Helmus1]. Poisson sampling produces an identicalindicating that an appropriate normalization accounting for differing sample sizes is potentially crucial in computing phylogenetic beta diversity for differently-sized samples.](pcbi.1002832.g005){#pcbi-1002832-g005}

Human Microbiome, Scale and Resolution {#s2b}
--------------------------------------

The human body is host to multiple microbial communities, whose combined total outnumbers our own cells by at least a factor of 10 [@pcbi.1002832-Costello1], and a community ecology perspective may be essential for a full understanding of the impact of the human microbiome on human health [@pcbi.1002832-Costello2]. We now apply our framework to such microbial communities, collected from 7 human subjects across 26 distinct habitats. This data provides an ideal testing ground to demonstrate the utility of our theoretical framework: the largest metacommunity tree we sample from has tips, each tip representing an individual sequence sampled in the study, which would render computational


null model approaches intractable. Also, the different community types, subjects and scales allow us to address how our community assembly hypotheses depend on the choice of local community and metacommunity.

### Comparing local community phylogenetic diversity with a null model of community assembly {#s2b1}

We now focus on the deviation of microbiome communities from randomly assembled communities. The reason that random sampling is such a crucial baseline is that it lies between two distinct phylogenetic community assembly processes: local communities with lower PD than random are phylogenetically clustered, a signature of environmental filtering, while local communities with higher than random PD are phylogenetically overdispersed, indicating competitive interactions. The true relationship between clustering and overdispersion and these ecological mechanisms is likely more complicated than this simple description [@pcbi.1002832-ValienteBanuet1], [@pcbi.1002832-Mayfield1], but itis a useful starting point [@pcbi.1002832-Mouquet1].

To evaluate the structure of a local community with respect to a given community assembly hypothesis, we need to make an assumption about the pool of individuals or taxa that this local community can draw on: the metacommunity. The 'true' regional pool of organisms that a given habitat from a given subject draws upon is difficult to define unambiguously, and so our approach is to allow for various definitions of the metacommunity, and examine the sensitivity of our results on these definitions. This relevance of metacommunity definition has been highlighted before [@pcbi.1002832-Swenson1], where it has been shown that different metacommunity sizes can lead to different conclusions about the most important ecological mechanisms structuring local communities, and our approach allows us to explore this


Q:

HTML5 Local Storage Between Pages

So I am new to the HTML5/JS programming scene, but I am really trying to learn quickly... I am looking to build a site that functions like a Jeopardy game, with a home screen that has a table with categories and point values that, on click, will hyperlink to a question page.
On the homepage I was looking to keep track of the points.  I have a textbox there coded as:
<input type="number" id="SamTotalPoint" value="0" readonly="readonly"/>

On the question pages, I have placed buttons that would ideally add points to the home page using local storage.  The button is coded as:
<input type="button" id="SamHist50" value="Team Sam" onclick="SamScoreKeeper(samPoint,50)"/>

Now I'm looking to connect the two.  On an external JS, I tried to define the function as:
 hoping local storage could solve the problem rather than using PHP.  The window alerts are just there so I could make sure the JS was doing the arithmetic.  Can anybody help me with this?  It would be most appreciated!

A:

When localStorage is modified, a storage event will be fired on all other pages that share the storage. You just need to handle the event, and retrieve updated data. This also works for sessionStorage.
document.addEventListener('storage', function(e) {
    // don't forget to take a look at the parameter - event object
    // update your page here, good luck
}, false);


will get a NullReferenceException when you call EmptyTextBox().
You can pass a reference of your MainForm to your SubForm's construtor (also remove your new MainForm line):
MainForm mf;
public SubForm (MainForm main)
{
    mf = main;
}

the Enabling Good Lives website the guidance, framework and survey for providers and families to share their innovative approaches: 1 April 2016

Analysis and summary of evaluations of innovative approaches, including providing regular summaries of key finding to the working group for their feedback and comments, completed: 30 July 2016

Phase 2: Identifying what works and why

Regular meetings of the working group to discuss the evidence: August – September 2016

Consensus on what works and why and report back to Senior Officials Group completed: 30 October 2016

Phase 3: Identifying the changes that could be made to the disability support system

Prepare and finalise the advice for the Government in consultation with working group and others: 10 December 2016

6 Risks

The key risks to be managed are:

unable to get sufficient evidence about innovative initiatives

the


New Zealand and internationally have been completed and/or are underway. These will form part of the evidence base, and include reviews and evaluations such as:

Putting People First

the demonstrations of the Enabling Good Lives approach in Christchurch and the Waikato

the New Model for Supporting Disabled People

Choice in Community Living

Whānau Ora

National Disability Insurance Scheme.

9 Related work

There is a wide variety of work underway that either relates to, or has implications for work planned for Action 4(a). It will be the responsibility of the lead agencies to undertake regular environmental scans to ensure the working group have all the information needed to undertake this work.

On this page

Progress update to November 2017

Status: On track - Green

Some timeframes were pushed back, but most are on track to meet revised deadlines. There are manyinitiatives currently occurring across government in the 0-5 space that are relevant to this work including the detailed design phase of the System Transformation for Disability Support, and the Ministry of Health review of Child Development Services.

Action Milestones:

Scope approved at the 11 March 2016 meeting of the Chief Executives’ Group on Disability Issues and Disabled People’s Organisations [complete]

The Reference Group has been meeting monthly. The last meeting was held on 17 October 2017, with the next one scheduled for 14 November. A Steering Group meeting was held on 14 September, and Working Group members have been invited to attend the upcoming Reference Group meeting, for a presentation and discussion on alignment with Education's new Learning Support delivery model and the Ministry of Health led System Transformation work.

Synthesis and


may be difficult.

A genuine commitment from the outset is a positive start. The escalation pathway provided through the Governance process provides for resolution of any issues.

Work may not proceed fast enough to make a difference for families already in the system.

Proposed phased approach enables rapid change and building over time.

Implementation costs may not be affordable / acceptable to Government.

Robust advice to Government will provide sufficient information for informed decision-making around scalable options.

A change of Government could result in loss of traction.

Improving supports for parents, family and whānau with children with disabilities is a cross-party priority

6 Evidence base

There have been many reports over the years that have identified concerns about the ability of parents, family and whānau to access the services and supports they need when they need them,People's Organisations on 19 August 2016.

1 Lead

Office for Disability Issues

2 Context: brief background, what is this action intended to achieve?

This action has been carried over from the 2014 Disability Action Plan. The main changes to the previously agreed scope are updating the milestones and the addition of risks.

Support for the exercise of legal capacity is considered a fundamental right that underpins the exercise of most other human rights. This issue particularly affects people with difficulty with communication and/or understanding information.

The population most likely to need support for the exercise of legal capacity generally includes, but not limited to:

o people with learning disabilities

o people with experience of mental illness

o people with experience of dementia

o people with other kinds of impairment that limits their ability to communicate, understand or retain


arrangements (including legislation, policies and practice) compare to the expectations of Article 12 and are there any gaps?

what are examples of leading practice (domestic and international) in relation to Article 12?

what is needed to achieve better implementation of Article 12, including options for implementation?

5 What is excluded from the scope of this action?

Implementation of any activity by government agencies or non-government stakeholders in relation to Article 12 is excluded from this action.

6 What are the timeframes for implementation?

Work on this action is expected to be progressed from July 2016 to June 2017.

7 What resources will the lead and partners contribute?

The Office for Disability Issues will dedicate staff time to work on this action.

The Office for Disability Issues has also contributed funding for Auckland Disability Law (in 2015/2016) andadvice on options to the Associate Minister of Health and the Minister of Justice by end of June 2017.

7 Risks

What are the risks to progressing this action, and what mitigations will be put in place against those risks?

Risk

Mitigation

Development of options may exceed the desired timeframe.

Ensure everyone involved is aware of the timeframes in advance, and when they will be expected to contribute

Members of project working and reference groups are unable to reach agreement on options to be presented to Ministers.

The Disability Action Plan Governance process will be asked to provide guidance.

Content of project provokes strongly held positions and views.

Involve range of perspectives, expertise, and experience in project through the reference group and wider networks.

8 Impact – what are we trying to achieve?

Outcome is development of high quality advice


use of section 29 orders for Māori service users

Refresh of Rising to the Challenge: The Mental Health and Addictions Service Development Plan 2012-2017

Other initiatives

Other projects and initiatives, aside from those identified in the Disability Action Plan, are being carried out to support the Choice and Control outcomes of the New Zealand Disability Strategy.

Transforming the disability support system

The Government has made decisions on the next steps for transforming New Zealand's disability support system. The transformation will be based on the Enabling Good Lives vision and principles, and informed by evidence of ‘what works’.in the middle of an attack which gives away the advantage. These types of opponents would be a lamb to the slaughter since you are forcing them to do something they would prefer not to do.
This is a more psychological ploy that will work against certain opponents. Of course, it goes without saying that you will have to play well since you are playing from behind. Play like a tiger and take advantage of every blink by your prey. Stalk (develop), stalk (secure king), stalk (arrange pieces to pounce), stalk (wait for a mistake -- blink), pounce.


for three replicates for each treatment.

Results
=======

Inhibition of IGF-1R is associated with antitumor activity in vivo
------------------------------------------------------------------

The antitumor effects were determined in the IGF-1R-dependent CRC sub-cutaneous xenograft tumors following treatment with IGF-1R antagonist MK-0646 or OSI-906. MK-0646 treatment for three weeks at 20 mg/kg dose once weekly inhibited the growth of the GEO xenograft tumors ([Fig. 1A and B](#f1-or-31-01-0087){ref-type="fig"}). Similar results were obtained in MK-0646 treated CBS xenograft tumor (data not shown). The final tumor volume and weight were significantly reduced in MK-0646 treated xenografts compared with the control ([Fig. 1C and D](#f1-or-31-01-0087){ref-type="fig"}). Results obtained by daily treatment of OSI-906 (40 mg/kg) for two weeks orally ([Fig. 2A and B](#f2-or-31-01-0087){ref-type="fig"}) were comparable to the MK-0646 treated tumor xenografts showing decrease in tumor growth. However, we observed \~10% body weight reductionin OSI-906 treated mice compared with the MK-0646 treated mice (data not shown), which may be attributed to inhibition of insulin receptor by the dual kinase inhibitor.

IGF-1R inhibition of apoptosis in vivo and in vitro
---------------------------------------------------

We assessed the apoptosis level of control and drug-treated xenografts using TUNEL assays. Comparable results were obtained for both IGF-1R antagonists. Both MK-0646 and OSI-906 treated GEO xenografts had statistically significant increase in apoptosis (p\<0.05) as compared with the control tumors ([Fig. 3A--D](#f3-or-31-01-0087){ref-type="fig"}). Based on the pro-apoptotic effects of both MK-0646 and OSI-906 *in vivo*, DNA fragmentation was performed *in vitro* on GEO CRC cells to determine cell death following IGF-1R antagonist treatment ([Fig. 3E and F](#f3-or-31-01-0087){ref-type="fig"}). In accordance with the *in vivo* study, both MK-0646 and OSI-906 treatment showed significant increases in apoptosis


to 70--80% confluency and treated with different doses of either MK-0646 or OSI-906 under GFDS for 48 h and performed DNA fragmentation assay as explained in Materials and methods (E and F).](OR-31-01-0087-g02){#f3-or-31-01-0087}

![IGF-1R inhibition on cell proliferation *in vivo* and *in vitro*. Ki-67 staining was performed on both MK-0646 and OSI-906 treated and control xenograft paraffin-embedded slides and statistical analysis was determined (A, B, C and D). In order to determine the *in vitro* effects of IGF-1R inhibition on proliferation, MTT assay was performed with different doses of OSI-906 under GFDS for 48 h (E).](OR-31-01-0087-g03){#f4-or-31-01-0087}

![Effects of IGF-1R inhibition on cell cycle *in vitro*. GEO CRC cells were grown to 70--80% confluence treated with OSI-906 under GFDS for 48 h and performed cell cycle analysis as explained in Materials andin the outfitting of German Luftwaffe aircraft.

During the war, production was further decentralized, Bosch produced in an ever larger number of factories, and relocated parts of its production to 213 plants in more than 100 locations.

On 12 March 1942, the company's founder, Robert Bosch, died at the age of 80.

Angela Martin and Ewa Czerwiakowski interviewed numerous former forced laborers and concentration camp prisoners of Dreilinden Maschinenbau GmbH and Trillke-Werke as part of a Berliner Geschichtswerkstatt project, researched the history of the two shadow factories, and published several books and exhibitions on the subject. In 2016, they published the website z.B. Bosch. Zwangsarbeit im Hildesheimer Wald.

Until 2000
After the second world war, Bosch established a partnership with the Japanese company Denso.

In 1964, the Robert Bosch Stiftung was founded. Bosch founded


a new development center in Schwieberdingen in 1968, and headquarters moved to Gerlingen in 1970.

In 1981, the company participated on an equity basis in the Telefonbau & Normalzeit GmbH that was renamed Telenorma in 1985, and acquired completely in 1987. In 1994, this part of the company was renamed as Bosch Telecom GmbH.

The most relevant inventions of the company until 2000 were the oxygen sensor (1976), the electric motor control (1979), the traction control system (1986), the xenon light for cars (1991), the electronic stability control (1995), the common rail direct fuel injection (1997), and the direct fuel injection (2000).

In 2000, Bosch sold the Private Networks area (nowadays, Tenovis and Avaya, respectively).

21st century
In 2001, Bosch acquired the Mannesmann Rexroth AG, which they later renamed to Bosch Rexroth AG.when Illies & Company set up a sales office in Calcutta. For three decades, the company operated in the Indian market only through imports. In 1951, Bosch set up its first manufacturing plant in India.

Currently, Bosch India has a turnover of over $3 billion and over 31,000 employees spread across 10 locations and 7 application development centers. 84% of Bosch India revenues come from its automotive business, with the remaining 16% split between its non-automotive businesses that include packaging, energy and building solutions, power tools and consumer retail. Bosch also has an R&D facility in Coimbatore and Bangalore, India. This is Bosch's largest R&D facility outside its home market of Germany. In September 2014, Bosch announced the launch of a locally developed eye-care solution in India. The company's


arising from the suppression of knowledge. This paper concentrates on the latter two, but I will briefly describe what is involved in the first category before setting it aside. Known unknowns are things outside the limits of 3 not with normative questions or moral responsibility, I will apply her categories in this way.3 Ignorance about knowledge and facts can be divided into three subcategories. Knowable recognised unknowns are something that could be found out given the right resources and motivation. In Roberts's paper these recognised unknowns that are knowable (i.e. the ignorance about the facts could be overcome) are called "knowable known unknowns", but this term can be philosophically confusing due to the tautology involved. Therefore I am referring to this category as knowable recognised unknowns throughout. Thistoo costly, while another one would rule it to be a justifiable expenditure. If Sell-A-Lot or Exciting Electronics has decided that it is too costly to put in the resources necessary to adequately monitor their supply chain in relation to, say, the working conditions in the factories, then these working 6 conditions remain knowable recognised unknowns to the organisations. Arguably this situation could (and should) be different, but such arguments need to be rooted in normative considerations outside simple cost and benefit analyses. More broadly put, when it comes to knowable recognised unknowns, the issue of whether ignorance is blameworthy or excusing can only be settled in the context of deciding the adequate focus for the organisation. Following Tuomela (2007, p. 15) and Laitinen (2014, p.218), this focus


be argued to include negligence towards safety. What is important for the topic at hand is that while the ethos determines a group's identity (and is part of what marks its continuation together with its historical and modal properties), it is in a state of flux (to what degree varies naturally a lot between each case). The ethos of a group is therefore not set in stone, as elements of it may change (and almost always do to some degree at least, especially when it comes to the large organisational-size groups). Examples are everywhere: corporations venture into new areas of production, political parties amalgamate new goals, the jurisdiction of local authorities change, university begins to offer courses in a new subject matter; it is easy to keep comingis not shared, in some cases it can be hard to draw a clear line on what information should be available to whom. In bureaucratic organisation there is a requirement for some ignorance for the focus to be on roles, rather than personal characteristics. Roles are narrowly defined for a more or less precise purpose that serves the organisation's goals, therefore ignorance of 10 Thank you to an anonymous reviewer for bringing this term to my attention. 13 irrelevant personal characteristics of the people you deal with help things to run smoothly. An effective balance between informal relations and procedures, established in the course of frequent face-to-face contact, and the ignorance that is required for orderly procedures is thus required in any bureaucracy (Moore and Tumin 1949, p.


the person should have realized what they were doing. Deficient investigation is the first type, either through failing to investigate properly, or failing to investigate at all. While this is not the case with Violet, Sharon could fall into this category if it were the case that she had failed to read an internal memo about possible problems with the new manufacturers' products. Preventing subsequent discovery presents the second case: a person has either failed to remove or introduced a condition which made it impossible for him to acquire true belief of x's wrongness. If information about faulty products was available in print at Exciting Electronics but Sharon missed this because she has never learnt how to read properly (a life-long secret she has just about managed toThis could be either due to personal failings on the part of the manager, or due to being too influenced by certain harmful organisational mental models. But this is beside the point: bad will is not necessary for the examples to get off the ground. Organisational fragmentation of information alone can produce morally inferior acts. Although there is no bad will, if the organisation does not take action to try to change its internal practices and communication flows after it has been made aware of the problems, then we can argue that it should care more. After all, it has come to know that the knowledge it has about the safety of its outsourced products is not robust enough to prevent such large-scale errors from happening. Still, some


organisational fragmentation of information is always necessary and can lead to unintended consequences. More generally, all collective action can result in outcomes that were completely unintended. Smith 14 The assumption is of course widely shared within moral responsibility literature, the quality of will account of blameworthiness is not exclusive to culpable ignorance literature. 19 argues that there is a degree to which we can be held accountable for the consequences of our actions, and this is linked to the outcomes falling within the predictable outcomes for that act. In other words, culpable ignorance arises only when the unwitting wrongful act falls within the known risks of the earlier act that infects the later act (Smith 1983, p. 551). This makes a separation between knowingly risking something and havingintend to let the wasp in, but when it stings you badly, he should express sadness at your pain and offer you comfort. He is not at fault and resentment towards him is therefore not warranted. The response to the pain caused by the sting indicates the importance attached to your interests, and any claims for him to respond are rooted in the fact that his agency led to the suffering, however unintended it was. In other words, "accountability for unintended consequences manifest an acknowledgment of the fact that one's projects have interfered with another's interests" (p. 143). This applies also to the unintended consequences of collective action, as we are complicit in the consequences of what we do together. If some harm is a direct consequence of


complete break down of, or damage to, such oxide structures can drastically degrade device performance, or destroy a device completely—having a significant detrimental impact on process yield or device reliability or performance.
A number of electric stresses—that may cause or contribute to the break down of gate oxide structures—occur during actual operation or testing of a post-fabrication semiconductor device. There are a number of electrical stresses, however, that occur during the fabrication of a semiconductor device that may potentially be as or more damaging than the post-fabrication stresses. Some such stresses are recognized and understood, and may be addressed in conventional fabrication processes. Other fabrication-related stresses may have not yet been recognized, or may have been recognized but not fully understood or addressed.
One apparently heretofore unrecognized or unaddressed phenomenonlayer or structure—capacitively couples with the charge already existing in the first conductive structure, overstress or full breakdown of the adjacent gate oxide often results. In many cases, the accumulated charge discharges to the substrate through the least resistive path (i.e., the gate oxide structure). This phenomenon is particularly problematic where the first and second conductive structures are disposed or configured in a capacitor or quasi-capacitor arrangement, having an insulating layer or structure disposed therebetween. Charge build-up and discharge is, in many cases, an inherent or intended operational characteristic of such arrangements. Unfortunately, although such structures and configurations are common and necessary in semiconductor device design and fabrication, their charge and discharge during device fabrication are often not recognized or accounted for.
As a result, there is a need


to different producers — makes up about half of the global gay porn market.

Straight men work in American gay porn, too, but not in such large percentages. According to Rod Barry, a former marine-turned-porn-star, straight porn actors in the U.S. earn about $400 for a scene. In gay porn it is three, five, or even eight times that amount.

But globalization has changed the wage structure of the porn industry. In Eastern Europe, men are willing to do porn for a lot less. “That’s the downfall of the business," Barry says. "The cheap guys from Europe flood the market with crap product."

Exactly how much gay porn is produced in Prague is impossible to estimate. Much of it is now done by opportunistic amateurs with cheap webcams at home, theirmuch porn if sex wasn’t stigmatized. “The anti-porn movement here is actually making porn more popular.”

Every time protest groups announce an anti-porn-month initiative in the Midwest, Shay says to himself: “Great, I’ll sell more.”

The prince of "Twinkopolis"

Alan Capier, an AVI Films porn star and cameraman, who has also performed under the names Felix Wallace, Alan Clarke, Filip Nowotny and Pavel Vlasek, among others, has been in the business for almost six years. He's worked for Higgins, Eurocreme, Man’s Art and others. He has been with more than 600 men and appeared in more than 100 hardcore films.

As an openly gay man, Capier is a rarity on the Prague market and one of the few who can perform without erection-enhancing drugs. “It’s practice, like anything else,” he says.

Over svarak,


them end up doing escort work, a polite term for prostitution.

Life with an alter ego

The majority of the Czech gay porn models, especially the occasional models, have regular day jobs and girlfriends. Some are married. There are college and high-school students, bartenders or unemployed. It’s not unusual to see cops, firemen and nurses. They typically keep their porn alter-egos secret.

Producers pledge confidentiality to the young Czech men cast in the movies, but it is becoming increasingly difficult to hide their real identities online.

Producers promise not to sell any of the movies in the Czech Republic, but can’t force their distributors to do the same. Producers block their websites from access from inside the Czech Republic, but easy-to-use online anonymizers will let anyone access any website. A few CzechInstitution {#s2a}
------------------------

This retrospective study included all acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients, aged 0-18 years, who developed IFI at our clinic between January 2001 and January 2013. The patients were identified by reviewing the medical charts of all AL patients. Children with ALL received the BFM-95 or BFM-2000 protocol and those with AML received the BFM-98 or BFM-2004 protocol. Children were hospitalized in single rooms without high-efficiency air filtration systems.

The medical, microbiological, and imaging records of the patients who met the inclusion criteria were reviewed for the following variables:

Demographic and clinical data: {#s2b}
------------------------------

Age and sex, leukemia type, remission status, and risk group of underlying disease at the time of diagnosis; the day and phase of treatment at which IFI developed (remission, induction, consolidation, maintenance);


positive, gram negative and fungal organisms from the lungs of mice. These actions are mediated in part by the pulmonary collectins which promote the aggregation, permeabilization and opsonization of organisms which are deposited at the air-liquid interface. In the first aim, we will test the hypothesis that KGF augments the innate immune defenses of the alveolar epithelium by induction of the collectins and antimicrobial peptides. The hypothesis to be tested in the second aim is that KGF augments the innate immune defenses of the alveolar epithelium by activation and recruitment of phagocytes to the airspace, through cytokine and collectin dependent mechanisms. The third aim will explore the collectin dependent and independent mechanisms of in vivo clearance of influenza A virus and several Gram negative pathogens, including Francisella novicida.on the task.

This finding, for me, connects back to the whole idea of the 'narrative' circuitry, versus the circuitry for "direct experience," that I wrote about in an earlier post, called the neuroscience of mindfulness. I think it's worth reposting some of this here, as it's so relevant.

and the brain

A 2007 study called "Mindfulness meditation reveals distinct neural modes of self-reference" by Norman Farb at the University of Toronto, along with six other scientists, broke new ground in our understanding of mindfulness from a perspective.

Farb and his colleagues worked out a way to study how human beings experience their own moment-to-moment experience. They discovered that people have two distinct ways of interacting with the world, using two different sets of networks. One network for experiencing your experience involves