the level of contact tracing. (**c**) Number of individuals whose contacts are traced each day per 1,000 persons. Relevant intervention actions are signaled by the vertical dashed lines in all panels.](nihpp-2020.05.06.20092841-f0004){#F4}

######

Mean and 95% C.I. of the number of normal hospitalizations, ICU hospitalizations and symptomatic individuals identified/traced (when applicable) at the peak of the epidemic per 1,000 people. The estimated availability of ICU beds is 0.21 beds per 1,000 people.

  Scenario                              Hospitalization     ICU                 Individuals traced
Los Angeles as an engineering undergrad, found he couldn't stand it, and got his degree in European history. That was followed by a
master's degree in journalism at Columbia - which led to another change of course: He became a Special Forces buck sergeant in the military. That experience was followed by a stint as an Army intelligence spy (in Italy), which somehow catapulted him into a career in the waste management business. If it is true that winemaking attracts characters to its faternity, maybe Bill Parsons' ultimate occupation was inevitable.

Advertisement

And, hey, for the things Parsons couldn't do himself, there was plenty of talent in the rest of the family. Teamwork is a daily mantra and everyone knows his or her role. Bill's focus is on marketing, but he


to load before device_initcall
 */
fs_initcall(init_acpi_pm_clocksource);

/*
 * Allow an override of the IOPort. Stupid BIOSes do not tell us about
 * the PMTimer, but we might know where it is.
 */
static int __init parse_pmtmr(char *arg)
{
	unsigned int base;
	int ret;

	ret = kstrtouint(arg, 16, &base);
	if (ret)
		return ret;

	pr_info("PMTMR IOPort override: 0x%04x -> 0x%04x\n", pmtmr_ioport,
		base);
	pmtmr_ioport = base;

	return 1;
}
__setup("pmtmr=", parse_pmtmr);
and current public officials have been working behind the scenes or, in some cases, directly for the casino and associated facilities. Whatever their past contributions to public service – and they are considerable – I believe those who have argued that these facilities should be public priorities may have lost their way. Some have strayed so far along the path toward conflict of interest that it is unclear as to whether they have broken the law or whether the law must be fixed.

• The design of the complex is too large and will further block rather than enhance the important linkages between the Downtown Eastside, including Chinatown, and False Creek.
• The stadium roof now litters our skyline – its design is disrespectful of 3 decades of careful work


Edgewater’s expanded casino by Vancouver City Council: 0

ABOUT BROKEN PROMISES TO THE CITY OF VANCOUVER

Projected return of expanded Edgewater casino to City of Vancouver: $10 million in new revenue from gambling

Projected revenue to City of Vancouver from Edgewater’s original casino in 2004: $10-12-million in new revenues

Actual annual return of Edgewater Casino to City of Vancouver over the past two years: $6.3 million

Promise to arts groups and charities in 2004: increased funding
What charities got in 2010: 14% less than they got in 1995
What BC Lottery Corporation got in 2010: about three times as much revenue as 1995.

Promise to bingo players and their funding recipients in 2004: New Planet Bingo hall at Edgewater
Status of promise in 2011: Never delivered

ABOUT PARAGON GAMING

Number of slot machines in Paragon’s only Las Vegas operation,a fight in a lounge that spilled outside.

ABOUT CRIME AND GAMBLING IN B.C.

The two best places to meet gangsters in B.C., according to Fred Pinnock, former Commander, Integrated Illegal Gambling Enforcement Team: in jails and in casinos

Date that B.C.’s Integrated Illegal Gambling Enforcement Team was disbanded by the provincial government: February, 2009

Date that BC Lottery Corporation was fined $670,000 by FINTRAC for repeated failure to monitor suspicious transactions, the first fine of its kind in Canada: Summer, 2010

Number of dollars involved in suspicious cash transactions at 2 casinos in Metro Vancouver, including $460k in 20’s in plastic bags, and a suitcase with $1.2 million in casino chips, revealed by CBC in 2010: $8 million.

Reaction of Insp. Baxter, head of RCMP Proceeds of Crime Unit, to these transactions: “suspicious”

Reaction


demonstrated both strong community support via a referendum, and strong local roots in the community. Paragon Gaming was one of the bidders in this process, but was unable to garner a single vote of support from the Missouri Gaming Commission.

US small market casino operations have notoriety, particularly vis-à-vis political corruption. In more than one instance, individuals with some connection to Paragon Gaming or their advisors have been implicated, charged, or convicted on political corruption charges. A detailed background check on Paragon Gaming is recommended, including investigation of the relationship of Paragon principles with Milton McGregor and Robert Sigler (shareholder in Paragon Gaming Missouri) of Alabama.

This is the first anniversary of the Olympics Opening Ceremonies. Today Shane Koyczan joins our coalition against the Edgewater mega-casino and against gaming expansionin North America — of Darius Milhaud’s operatic adaptation of the trilogy’s finale, “La Mère Coupable” (“The Guilty Mother”). No commercial recording exists of this work, which was first presented in Geneva in 1966, and a smut-and-blood staging in Vienna in 2015 didn’t exactly broaden its appeal. Milhaud’s hyperactive score, full of barbed dissonances, certainly does little to endear itself to the listener, and the material is darker than in “Barber” and “Figaro.” As On Site Opera’s music director, Geoffrey McDonald, said recently between rehearsals, “It takes these people everybody knows and transplants them to a Raymond Carver story.”

The plot revisits Count Almaviva’s household 20 years after the turbulent events surrounding the marriage of the count’s barber, Figaro, to the countess’s maid, Susanna. The guilty mother of the


at environmental evidence which shows that the SGRs and AXPs can not be due to a purely innate property, such as superstrong magnetic fields[@thompson95].

The Environments of SGRs and AXPs {#environment}
=================================

If the unusual properties of SGRs and AXPs were due solely to an intrinsic property of the neutron star, that developed independently of the external environment, then the characteristics of the interstellar medium which surrounded the AXP and SGR progenitors should be typical of that around the massive O and B stars which are progenitors of all neutron stars. Observations clearly show that the majority of neutron stars are formed in “superbubbles”: evacuated regions of the ISM which surround the OB associations in which the massive progenitors of most neutron stars live. The supernovae from the massive O andOceano services district set to hire Paavo Ogren as general manager

In what could be seen as a coup for a troubled agency, the Oceano Community Services District board is poised to hire a new general manager on Wednesday — Paavo Ogren, the current public works director for San Luis Obispo County.

If his hiring goes forward, Ogren would leave his job overseeing 180 employees and eight divisions to head up the Oceano district, a small services agency with six employees, a tight budget and frequent turnover in its general manager spot.

He would become the ninth person in that position in seven years, with the last two managers fired for cause.

Ogren, who has spent much of his career with the county including the past seven years as public works director,


fill a vacant accounting job, saving about $65,000 plus benefits. Ogren doesn’t plan to take a car allowance, saving $3,600 a year.

And district officials expect that Ogren will be able to complete some tasks often assigned to outside consultants, saving the agency further expenses, a staff report said.

Ogren said he would need to give 30 days’ notice to the county before leaving.

In his role with the county, Ogren has overseen a number of water resource projects, including the Nacimiento Water Project, a 45-mile pipeline that carries millions of gallons from the lake to residents and businesses within San Luis Obispo County.

He also has been directly responsible for the massive Los Osos sewer project, taking criticism from its opponents.

Ogren’s past experience includes four years as chief financial officer fortwo local engineering firms. Ogren said he plans to re-activate his certified public accounting license, which is currently inactive.

In a statement of interest submitted to the district, Ogren wrote that his interest in becoming Oceano’s general manager “is the same as in January 1988 when I started my first management position in government — simply stated, to serve the public good.”

“Working at that community level is something I value a lot,” Ogren added Friday. “I don’t have any concerns about some of the challenges that they’ve had. There’s a lot of stuff that needs to be worked on.”

Over the years, district officials have struggled to complete normal district business, like annual audits, in a timely manner.

Complicating their efforts has been frequent turnover in the general manager position. Since


   under the terms of the GNU General Public License as published by
    the Free Software Foundation, either version 3 of the License, or
    (at your option) any later version.

    OpenFOAM is distributed in the hope that it will be useful, but WITHOUT
    ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or
    FITNESS FOR A PARTICULAR PURPOSE.  See the GNU General Public License
    for more details.

    You should have received a copy of the GNU General Public License
    along with OpenFOAM.  If not, see <http://www.gnu.org/licenses/>.

Class
    Foam::fv::leastSquaresGrad

Description
    Second-order gradient scheme using least-squares.

SourceFiles
  within mice models \[[@CIT0015]\]. Given the facts that IMN and FSGS shared certain pathological traits, such as injured cytoskeletons and slit diaphragms of podocytes, it was conjectured that biomarkers (e.g., miR-193a) that played a core role in FSGS development could also matter in the pathogenesis of IMN. Intriguingly, the facilitating effects of miR-193a on nephropathy were, to some extent, dependent on suppression of Wilm's tumor protein (WT1) \[[@CIT0015]\], which was usually suggestive of quantitatively reduced podocytes and damaged glomerular filtration barrier \[[@CIT0016],[@CIT0017]\]. The WT1 also functioned as a regulator for podocalyxin (PODXL) \[[@CIT0018]\], which was capable of preventing adhesion of foot processes and maintaining regular structure of podocytes \[[@CIT0019]\]. Summing up the above, miR-193a, WT1, and PODXL were, respectively, accountable for disordered functioning of podocytes, suggesting themselves as


in his efforts to enforce their attendance before the expiration of the term, and on his motion for a new trial present them to the court for examination; if, with all of his efforts, he is unable to have the witnesses personally present, he should, if practicable, secure their ex parte affidavits, which should be presented for the consideration of the court, which, on the motion for a new trial, will review the whole case and correct any error prejudicial to the defendant which may appear in any part of the proceeding."
(Hn 9) This rule has been reaffirmed in Eslick v. State, 238 Miss. 666, 119 So.2d 355 (1960); Shoemaker v. State, 222 Miss. 257, 75 So.2d 647 (1954). Appellant did not comply with this rule, although heto the jury, shall mark all instructions * * *." (Emphasis supplied.)
(Hn 22) We are of the opinion that defendant was not prejudiced in this case because the judge, who was required to give the instruction, read only the instructions setting out the form of verdict. We do not condone the action of the court in calling the attention of the jury especially to any instruction, and we are of the opinion that it is much better form for the court to permit attorneys in the case to read the written instructions given by the judge to the jury and permit it to take them out when it retires for the consideration of the verdict. In the present case, however, we do not believe that this case should


Cannabis Startup Explains Why Venture…

Cannabis Startup Explains Why Venture Capital is Largely Unavailable

July 22, 2016 at 5:54 pm

Published by NCV Newswire

In episode 40 of Investing in Cannabis, Brandon David interviews Marshall Hayner, who is a founder participating in the Gateway Incubator program. Hayner, who hasn’t yet renamed his company, joined the inaugural class with a B2C platform but has pivoted to B2B. Hayner is trying to use a bitcoin payment system in the cannabis industry by hiding bitcoin from the user experience and creating a plug and play type of solution using blockchain technology.

Gateway founders Ben Larson and Carter Laren participated in the interview as well. They were impressed with Hayner’s background as a cryptocurrency expert as well as his experience with cannabis delivery. Law firm Morgan Lewissignificant for three groups of pathogens: bacteria (r = 0.3016, *df* = 213, *p \<* 0.0001), directly transmitted viruses (r = 0.2142, *df* = 214, *p* = 0.0015), and helminths (r = 0.2590, *df* = 213, *p* = 0.0001). In contrast to previous results ([@pbio-0020141-Allen1]), we found no significant relationship between PID species richness and mean annual temperature. Finally, only the relationship between bacteria species richness and mean annual precipitation was significant (*r* = 0.1987, *df* = 213, *p* = 0.0034). Very little difference was observed among hemispheres concerning these relationships (data not shown).

###### Relationship Between PID Species Richness by Etiological Group and Four Bio-Climatic Factors

![](pbio.0020141.t002)

Pearson\'s correlation (*r*), sign of slope (+/−) and significance levels (*p*) are given. *\** indicates significance levels which become nonsignificant after the Bonferroni


the total number of human diseases known within the boundary limits of each country. It has been argued that species richness increases with increasing area sampled ([@pbio-0020141-Hawkins1]; but see [@pbio-0020141-Rohde2]). Therefore, we included total surface area per country (in square kilometers) in our analyses, in order to control for its effect in the multivariate analysis. Similarly, we considered human population size and human population density per country (in persons per square kilometer), both highly colinear with surface area, as possible explanatory factors, since the number and density of human hosts may also influence parasite species richness ([@pbio-0020141-Anderson1]; [@pbio-0020141-Guegan2]). In addition, we considered a variety of environmental, demographic, and economical factors. Variables selected as environmental factors for each country were (1) continent, (2) hemisphere, (3) whether the country wasmatching countries. The decision rule, ensuring significance at α = 0.01, consisted in rejecting the null hypothesis of the absence of spatial correlation if the correlation coefficient obtained for nonpermuted data was maximum among all 100 coefficients. The calculation of *I* using Monte Carlo simulations indicated no strong spatial autocorrelation (*I* ~0~ = 0.08 equals *I* ~s~ = 0.11 at α = 0.01), suggesting that the close similarities between PID species richness and composition observed between neighboring countries conforms to the latitudinal diversity gradient.

### Nestedness analysis {#s4a4}

We also employed Monte Carlo simulations ([@pbio-0020141-Manly1]; [@pbio-0020141-Guegan1]) to evaluate PID spatial organization at the largest scale. We used the data matrix of presence/absence values for 229 different pathogen species of the total dataset comprising 224 countries. We assessed the degree of


these guys that really never did anything with their lives because I don’t think they ever had any interest in art in a sense that they didn’t see the beauty in it, so they didn’t travel.”

He eventually found Jon Syverson, who has been the drummer of Daughters since its inception.

“He had the same interests, and he knew some people that liked music, and we started playing. It was great to be able to eventually find other people that we could turn each other on to things,” said Marshall.

His friendship with Syverson went much deeper than a musical connection. At a point where Marshall was homeless and sleeping in a park, he found residency with Syverson in his parents’ basement.

Marshall was so confident in his friendship with Syverson, heQ:

How to include GET & POST data in PHP error log

Is there a way to have PHP log errors to a file or email me errors INCLUDING $_POST[] & $_GET[] and $_SERVER[] data?
Right now I get a log of PHP FATAL and WARNING errors and 404 NOT_FOUND errors but it's hard to debug some errors without knowing things like user input and the referrer.
Thanks

A:

error_log(print_r($_POST, true));
error_log(print_r($_GET, true));

Put that into a custom error handler and it'll log both for you (the 'true' parameter makes print_r return text instead of outputting it).
You might need to boost the max line length in the error log with log_errors_max_len, as it defaults to 1024 chars and will truncate everything after that (it won't split >1024 char data across multiple lines).


to anti-aliasing.
 * <p>
 * NOTE: its possible for the ScreenMapGeometryReplacer to be running at the same time as the
 * ScreenMapPredicate or FeatureScreenMapPredicate. However, the features handed to this class will
 * have already go through the filtering.
 */
public class ScreenMapGeometryReplacer implements Function<SimpleFeature, SimpleFeature> {

    ScreenMap screenMap;

    boolean replaceWithPixel = true;

    public ScreenMapGeometryReplacer(ScreenMap screenMap) {
        this.screenMap = screenMap;
    }

    public ScreenMapGeometryReplacer(ScreenMap screenMap, boolean replaceWithPixel) {
        this.screenMap = screenMap;
        this.replaceWithPixel = replaceWithPixel;
    }

    /**
     * if the features is fully inside a// right handed (clockwise)

        coords[0] = new Coordinate(bbox.getMinX(), bbox.getMinY());
        coords[1] = new Coordinate(bbox.getMinX(), bbox.getMaxY());
        coords[2] = new Coordinate(bbox.getMaxX(), bbox.getMaxY());
        coords[3] = new Coordinate(bbox.getMaxX(), bbox.getMinY());
        coords[4] = new Coordinate(bbox.getMinX(), bbox.getMinY());

        return geometryFactory.createPolygon(coords);
    }

    public Point createMidPoint(Envelope bbox, GeometryFactory geometryFactory) {
        return geometryFactory.createPoint(bbox.centre());
    }

    public LineString createDiagonalLine(Envelope bbox, GeometryFactory geometryFactory) {
        Coordinate[] coords = new Coordinate[2];


 coords[0] = new Coordinate(bbox.getMinX(), bbox.getMinY());
        coords[1] = new Coordinate(bbox.getMaxX(), bbox.getMaxY());

        return geometryFactory.createLineString(coords);
    }

    // create a shape that is the geometry's "bbox" size
    public Geometry getSimplifiedShapeBBOX(Envelope e, GeometryFactory geometryFactory,
            Geometry g) {

        if (e.isNull())
            return null; // if there's isn't an envelope, we cannot make one...

        if (g instanceof Polygon) {
            return createBBoxPolygon(e, geometryFactory);
   In the news:

UCLA women’s basketball ends weekend with a win

Posted:

February 3, 2014

12:00 am

Senior guard Thea Lemberger was fouled multiple times against the Washington State Cougars. She converted 11 out of the 12 ensuing free throws to contribute to the Bruins' 79-72 win.
Joseph Chan/Daily Bruin

The only sounds audible in Pauley Pavilion were the Bruin player’s
footsteps as she stepped up to the line.

The ball missed the mark, and the silence was cut by a collective groan coming out of the stands.

It happened 14 times in total on Friday. For every time the UCLA women’s basketball team failed to convert from the line, the Washington Huskies responded with swift guard play, getting penetration in the paint or managing to find an open shooter. Finally, the Bruins fell 58–70 to the visiting


(HR) were monitored at sea level and during high altitude (i.e., 4300 m in a hypobaric chamber) before pretest (PRE-T) and 60 h after posttest (POST-T) for the last IHE or SHAM treatment. Over the 6 to 7 days of IHE, resting SaO2 increased from 75+/-1% to 81+/-3% in the IHE group, while the SHAM group remained at 98+/-1%. From PRE-T to POST-T at 4300-m exposure, both the IHE and SHAM groups had significantly higher sleep SaO2, fewer desaturation events per hour, and an increase in the percentage of time asleep while sleeping (sleep percent). The IHE group, but not the SHAM group, had significantly lower sleep HR and a trend to more awakenings during the POST-T 4300-m exposure. These results indicate that although IHE treatment induced significantQ:

Can't get information that's inside an array

I'm trying to get information that's inside an array but can't, every time returns an undefined statement.
That's the array, it's inside the variable 'RESULTADO'
debug   {"recordType":"customrecord5",
         "id":"1",
         "values":{
           "CUSTRECORD4.custrecord6":[{"value":"11",
                                       "text":"11 CP BUSINESS : Empresa Teste"}],
           "CUSTRECORD4.custrecord5":[{"value":"7",


The State Transport Department officials conducted a raid against city cabs at Sadarahalli Toll on Airport Road, Devanahalli on Friday and seized 100 taxis belonging to Ola which have been operating illegally in the city.

Joint Commissioner of Transport Department, Narendra Holkar said that these cabs were found running with state taxi permits and charging exorbitant fares against the rules.

Cabs are supposed to charge fares only according to the norms laid down by the Government. On the contrary, they were found to be charging high fares.

These seized cabs did not have digital fare meters fitted rather installed mobiles with GPS connectivity which displayed defective and higher fares. In some cabs, it was found that fares were levied at 10 times higher rate than the rate fixed by Government. Cabssubstantial initial clearance is provided between the outer air seal and the blade tips to prevent destructive interference. Resultantly, the clearance at equilibrium conditions is larger than desired and a portion of the working medium gases leaks over the tips of the blades. Such leakage of medium over the blade tips limits the obtainable stage efficiency and engine performance.
In modern engines, the tip clearance between the rotor blades and the outer air seal is reduced by cooling a portion of an engine case. A cooling medium, such as air pressurized by an upstream compression stage, is typically used for the cooling. U.S. Pat. No. 4,019,320 to Redinger et al. entitled "External Gas Turbine Engine Cooling For Clearance Control" is representative of structures in which the diameter of an


that mutational processes could completely obscure even noncoding sequences within such a short evolutionary time such that the extant form of the AFGP nongenic ancestor should remain identifiable. We, therefore, decided to track the AFGP genotype and its homologs within the gadid phylogeny to pinpoint the ancestral DNA site of origin and reconstruct the gadid AFGP evolutionary path. Here, we report the identification of the noncoding founder sequence and the mechanism by which it gave rise to a new functional gadid AFGP gene. Our results also show that the gadid AFGP evolutionary process likely represents a rare example of the proto-ORF model of de novo gene birth (6, 17) where the noncoding founder ORF existed well before the novel gene arose.

Results and Discussion

At the minimum, de novo formationto lift shape your breasts a step by step nutrition and workout guide for adding lift and shape to your bust fit expert series book 2 because this is pdf file

no short description best breast exercises simple steps to lift shape your breasts a step by step nutrition and workout guide for adding lift and shape to your bust fit expert series book 2 because this is doc file


Continuous wave terahertz spectrometer as a noncontact thickness measuring device.
We present a low cost terahertz (THz) spectrometer with coherent detection based on two simple and robust dipole antennas driven by two laser diodes. The spectrometer covers frequencies up to 1 THz, with a peak signal-to-noise ratio exceeding 40 dB for a lock-in integration time of 30 ms. We demonstrate that the thickness profile of a sample can be reconstructed from an acquired THz image.GmbH, Teltow, Germany) at a 250 Hz sampling rate \[[@B19]\]. Calibration and calibration-accuracy validation were performed prior to each experiment using the standard EyeLink routine.

2.4. Analysis {#sec2.4}
-------------

Eye movement recordings were analyzed offline using custom-written software in Matlab. The first 3 seconds of data was discarded. Instantaneous eye velocity was calculated by taking the first derivative of horizontal eye position over time. Fast phases (saccades) were removed using a velocity threshold of 10 degrees per second (i.e., twice the stimulus velocity). A sine-wave was fitted to the remaining velocity signal, yielding a fitted peak eye velocity (see [Figure 1(c)](#fig1){ref-type="fig"} for an example).

The eye velocity gain was calculated for each subject, contrast, and spatial frequency by dividing the fitted peak eye velocity by the peak stimulus velocity (fixed at 5 deg/s). Per


beliefs that you have at the moment just happen to be the perfect fit for the reality that you have been experiencing. At the same time, there are always better ways to live, better ways to reach our goals, better ways to understand reality. Belief systems must be always analyzed and optimized in order for us to keep growing.

Your belief systems will actively fight whatever challenges them. Why wouldn’t they? They’ve taken you this far right? This is why a culture shock is so impacting, it’s because it challenges our belief systems so hard, that you are forced to change them to adapt to the new environment. Adapting to something new does not feel nice, it’s not uncommon to feel anxious and frightened, but these emotions are normalbelief systems. You’ll need to start reframing your reality and affirming it, even while others refuse it.

First, What do you want to do? Better said, Who do you want to be?

“Seek out that particular mental attribute which makes you feel most deeply and vitally alive, along with which comes the inner voice which says, ‘This is the real me,’ and when you have found that attitude, follow it.”

― William James, The Principles of Psychology

Second, become self-aware, identify your current belief systems, identify your frames, notice when you become anxious, when you become happy or when other frames are imposed on you. Notice yourself on every level, don’t push anything away, rather use it as valuable information.

Third and lastly, reframe. Adopt in your head that new you and reframe


Father’s Day Flowers

For great Father’s Day gift ideas, turn to Colonial Florist in Orlando, FL. Flowers aren’t just for Mother’s Day, surprise Dad with a Father’s Day gift to brighten his whole week! We offer flower delivery to Orlando or nationwide!10^−1^ (∼16,700 ppm); triethylamine, 10^−2^ (∼750 ppm); and propionic acid, 10^−1^ (∼390 ppm). Each trace represents the mean of 10 presentations; error bars indicate ± 1 SD.](pbio.0060009.g001){#pbio-0060009-g001}

![Changes in Fluorescence from ssDNA and OliGreen Dye Sensors during Short Odor Sniffs\
(A) Responses of a sensor made from OliGreen alone.\
(B) Responses of a sensor made from 20 μl of 10 μM oligomer SEQ01, stained with OliGreen.\
(C) Responses from SEQ01 to 10 repeated applications of 10^−1^ propionic acid (∼390 ppm), demonstrating return to baseline between sniffs. These 10 responses were used to calculate the mean shown in (B). See [Figure 1](#pbio-0060009-g001){ref-type="fig"} for details of odor presentation, odor dilutions, and description of data representation.](pbio.0060009.g002){#pbio-0060009-g002}

Responses using ssDNA {#s2b}
---------------------

Because different dsDNA sequences did not show odor responses that were modified by changes in sequence, we


then tested sensors made from short, ssDNA oligomers stained with the fluorescent dye OliGreen (Molecular Probes). OliGreen dye alone showed a decrease in fluorescence upon exposure to propionic acid, but little change to the other odors tested ([Figure 2](#pbio-0060009-g002){ref-type="fig"}A). In contrast, SEQ01 (22 bases long; see sequence descriptions for SEQ01--SEQ30 in [Table S1](#pbio-0060009-st001){ref-type="supplementary-material"}) stained with OliGreen and dried onto a polyethylene substrate had a markedly different odor response profile ([Figure 2](#pbio-0060009-g002){ref-type="fig"}B) from OliGreen alone and from those using dsDNA and YO-PRO. This sensor sequence showed an increase in fluorescence in response to propionic acid and methanol (to which OliGreen alone did not respond), with relatively little change to the other odors tested. Furthermore, as shown in [Figure 2](#pbio-0060009-g002){ref-type="fig"}C, the propionic acid signals from this sensing material returned to(550 nm, BW 70 for OliGreen and YO-PRO; 600 nm, BW 10 for Cy3) and is monitored by photodiodes. Thus, there is an LED/bandpass filter/sensor/bandpass filter/photodiode set for each sensor channel. Electric current produced by each photodiode is converted to voltage, amplified, and digitized (every 100 ms) over the time of the sniff duration (1--2 s) at nominal 20-bit resolution. The digital signals are recorded and processed by an embedded microprocessor. User control of the device is via a touch screen panel. The current device is self-contained, hand-held, weighs about 1.5 kg, and is about the size of a facial tissue box.

Sensor tests in the electronic nose. {#s4b}
------------------------------------

DNA was diluted to the desired concentration (0.2--50 ng/μl) in TE (10 mM Tris base, 0.5 mM EDTA, pH 8.0) or


Tris-NaCl (2 mM Tris base, 11 mM NaCl, pH 8.0). Twenty μl of dilute DNA was mixed with 1 μl stock solutions of YO-PRO (1:40 in Tris-NaCl) or OliGreen (1:1 in Tris-NaCl) and incubated at room temperature for 5 min. Dye-only controls were made of 1 μl dye stock in 20 μl TE or Tris-NaCl. DNA/dye mixtures were applied to a substrate of acid-washed 16xx polyethylene silkscreen (10 mm × 12 mm) and allowed to dry for 25 min. Each sensor was rinsed in 70% ethanol for 5 min, allowed to dry, and then attached to supports on glass cover slips for testing in the electronic nose device. The dried DNA material adhered to the silkscreen mesh without occluding the openings. The exact thickness is unknown, but based

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             style="max-width: 80%; border: 4px solid lightgrey; border-radius: 2px;" />
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        <?php echo __('Coordinates') . ': ' . $post['coordinates'] ?>

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Q:

MongoDB - Sorting a query twice?

right now I am using this query to get my result and sorting it like this to make a highscore list. This works as planned with the query below.
However, I want to be able to sort them if there is two results with equal value.
If there are two results that have the value 5, I want to sort it by time. So I get the one with the highest score, and the one who registered the result first. I have mongoDB's 'createdAt' and 'updatedAt' that I want to use.
 User.find().sort({score: -1}).limit(10).exec(function(err, users) {

 });

Any pointers in the right direction is appreciated.

A:

You could try:
User.find().sort({score: -1, updatedAt: 1}).limit(10).exec(function(err, users) {

});

This will sort by score descending, followed by updatedAt ascending. Mentioned here.

6 hours, the earliest time point studied ([Fig. 1](#fig01){ref-type="fig"}B). These data suggest that, similar to *Melk* expression, *FoxM1* is preferentially expressed in proliferating murine NPCs.

![FoxM1 expression is restricted in neural progenitor cells in the mouse brain. **(A):** Reverse transcription polymerase chain reaction (RT-PCR) analysis for *FoxM1* and *Melk* expression during brain development. **(B):** RT-PCR analysis for *FoxM1* and *Melk* in neural progenitor cells with or without differentiation. Expression is compared with the differentiation markers for neurons (*neurofilament heavy chain* \[*Nfh*\]), astrocytes (*Gfap*), and oligodendrocytes (*proteolipid protein* \[*Plp*\]). For (A) and (B), *Gapdh* is used as internal control. **(C):** Left panels, top two images indicate immunohistochemistry for FoxM1 (green) and Sox2 (red) in mouse brains of embryonic day 17 (E17). Lower four pictures, immunofluorescence for FoxM1 (green) and Tuj1


region of FoxM1 isoform a, that is not present in the translationally active form of FoxM1, isoform b ([Fig. 1](#fig01){ref-type="fig"}E) \[[@b27]\]. Overexpression of FoxM1 (isoform b) resulted in a twofold enhancement of NS formation ([Fig. 1](#fig01){ref-type="fig"}E; Supporting Information [Fig. S2](#SD1){ref-type="supplementary-material"}). Although siRNA-mediated silencing of the inactive FoxM1 (isoform a) did not alter the growth of NS compared with the nontarget control, siRNA directed against the common region of FoxM1 (isoforms a and b) resulted in a significant decrease in NS numbers ([Fig. 1](#fig01){ref-type="fig"}F, right panel; Supporting Information [Fig. S2](#SD1){ref-type="supplementary-material"}). Collectively, these data suggest that FoxM1 is essential for the growth of murine NPCs derived from embryonic brains in vitro.

FoxM1 Expression Is Markedly Elevated During Gliomagenesis
----------------------------------------------------------

Accumulating evidence suggests that GSCs and their somatic counterparts, NPCs, share various fundamental signalingtargeting three different sequences for FOXM1 (left). RT-PCR analysis for *MELK* and *FOXM1* expression in GBM neurospheres treated with different doses of siRNA targeting MELK (right) *n* = 5. **(D):** Upper panel: Overexpression of Empty-EGFP (control) + MELK-*Flag (Flag-MELK*), EGFP-FOXM1 + MELK-*Flag*, or EGFP-FOXM1 + MELK D150A-*Flag* plasmids in HEK293 cells are processed to GFP-trap followed by immunoblotting with anti-*Flag* antibody. Middle panel: Autoradiogram displaying in vitro phosphorylation of FOXM1 by the kinase domain of MELK (1--340). Lane 1: FOXM1 + ATP-Mg (no kinase); lanes 2 and 6: FOXM1 + ATP-Mg + MELK (1--340); lane 3: FOXM1 + MELK (1--340) (no ATP-Mg); lane 4: FOXM1 + ATP-Mg + CDK2/CyclA; lane 5: FOXM1 + ATP-Mg + CDK2/CyclA + roscovitine; lane 7: FOXM1+ ATP-Mg + MELK1--340(D150A). Lower panels: Coomassie staining


with the FOXM1 mutant vectors lacking the ability of PLK1 to bind FOXM1 either partially (single mutation vectors) or completely (double mutation vector) ([Fig. 5](#fig05){ref-type="fig"}E). Transgenic expression of the double mutation vector (FOXM1 596/678), but not the single mutation vectors (FOXM1 T596A and S678A), almost completely abrogated MELK-driven *FOXM1* activation both in 293T cells and GSCs. Taken together, these data indicate that the MELK-driven *FOXM1* activation is dependent on both the initial binding and subsequent trans-phosphorylation events by PLK1 in GSCs.

Siomycin A Abrogates FOXM1-MELK Interaction
-------------------------------------------

Previously, the thiazole antibiotic Siomycin A was identified as a FOXM1 inhibitor by diminishing its protein and mRNA abundance, and we recently discovered that Siomycin A also reduced MELK expression in GSCs in vitro \[[@b9], [@b18], [@b40]\]. Consistent with these findings, flow cytometry demonstratedas existing cancer stem cells may not be sufficient; instead, combination of non-cancer stem cell-targeted therapies and cancer stem cell-targeted therapies appears to be mandatory. Our data indicate that Temozolomide treatment increased, while Siomycin A decreased, both FOXM1 and MELK expression in GSCs. One interpretation of these data is the preferential eradication of non-stem tumor cells and subsequent enrichment of GSCs after treatment (selection of therapy-resistant tumor cell population; the clonal evolution theory). Alternatively, Temozolomide may induce phenotypic changes of the treated GBM cells and may increase FOXM1 and MELK expression (the molecular evolution theory). It is also possible that both theories are true. Future studies will address this open question.

CONCLUSION
==========

In this study, we demonstrated that the oncoprotein FOXM1 is regulated by the mitotic kinase MELK for its


to a limited number of individual molecular targets.

Another recent instance of a mechanism-based therapy is represented by the development of compounds targeting the "death-receptors" TRAIL-R1 and TRAIL-R2 to selectively induce apoptosis in cancer cells [@pone.0051654-Johnstone1]. The development of such agents is based on the rationale provided by studies showing that knocking out of TRAIL or blockage of TRAIL-receptors leads to enhanced tumor and metastasis formation *in vivo* [@pone.0051654-Takeda1] and that loss of TRAIL-receptors expression in human cancer tissues correlates with poor prognosis and tumor recurrence (Reviewed by Walczak and colleagues [@pone.0051654-Walczak1]). In this regard, we could recently show that membrane staining for TRAIL-receptors determines the prognosis of patients affected by hepatocellular carcinoma [@pone.0051654-Kriegl1] and that the expression of the TRAIL-binding soluble decoy receptor OPG correlates with tumor stageMSI-phenotype
  Instable         69 (35%)
  Stabie           126 (65%)

TRAIL-R1 and TRAIL-R2 staining in colorectal cancer samples {#s3b}
-----------------------------------------------------------

To assess the staining of TRAIL-receptors in tumor samples we first performed a semi-quantitative analysis based on the categorization of samples according to the absence of staining, or the presence of a weak or strong staining intensity for the respective receptors. According to this criterion, 87 (38%) of colon cancer samples showed a strong positive staining, 129 (56%) showed a weak staining, whereas 15 (6%) samples stained altogether negative for TRAIL-R1 ([Figure 1](#pone-0051654-g001){ref-type="fig"}). As TRAIL-R2 in tumor samples was examined, a strong staining was observed in 110 (48%) of cases, a


tumors in early stage with no metastasis undergoing surgery only.

Prognostic relevance of TRAIL-receptors staining intensity {#s4b}
----------------------------------------------------------

In agreement with previous studies [@pone.0051654-Strater1], [@pone.0051654-VanGeelen2], [@pone.0051654-Ullenhag1], in our cohort the vast majority of samples showed positive staining for TRAIL-R1 and TRAIL-R2, roughly half of samples showing a strong staining ([Figure 1](#pone-0051654-g001){ref-type="fig"}). As we assessed the prognostic significance of TRAIL-receptors staining, TRAIL-R1 intensity staining scores (strong vs. low/no-staining) showed a significant correlation with survival in the long-rank test, higher TRAIL-R1 staining intensity being associated with better survival (p = 0.008, [Figure 4A](#pone-0051654-g004){ref-type="fig"}); in contrast, TRAIL-R2 staining intensity, KRAS-status, the relative amount of the splice variant KRAS4A or MSI-phenotype showed no correlation with survival ([Figure 4C](#pone-0051654-g004){ref-type="fig"}, [Figure S2](#pone.0051654.s002){ref-type="supplementary-material"}). These results are in agreement with previous studies which reported a positive correlation between patients\' survival andcell lines showed the maximal differential expression of this splicing variant of KRAS between these two cell lines (Abubaker et al. J Pathol 2009; 219: 435--445). As shown in panel A, accordingly to this previous report, KRAS4A production was about sevenfold higher in SW948 than in HCT15 cells. Moreover, the dynamic range of the measurement was very high as the calibration curves displayed linear slopes and linearity was granted for at least four log-scales down to 100 molecules (panel B).

(TIF)

######

Click here for additional data file.

######

**Correlation between TRAIL-receptors staining intensity and clinico-pathological variables in tumor samples.**

(PDF)

######

Click here for additional data file.

######

**Correlation between membrane staining of TRAIL-receptors and clinico-pathological variables in tumor samples.**

(PDF)

######

Click here for additional data file.

######

**PCR primers.**

(DOC)

######

Click here for additional data


xenophobic and is fighting against a logic of exponential growth. And the immigration threshold requested by Ecopop is still higher than in other European countries.

“It is not a racial issue. It is really a problem of numbers. With 73,000 more people coming in each year, it represents 40000 more homes to build, and 56,000 more cars! That’s what immigration induced in 2013. We just want to reduce the number of people allowed in the country, to have a lesser impact on the landscape,” says Messere.

Arguments the Swiss government rejects amid fear that Ecopop’s initiative will compromise the bilateral agreements that govern trade between Switzerland and the European Union.

Based on freedom of movement, the agreements have already been questioned after the February vote.

If Ecopop is successful that will createtons CO2). It then applies an adjustment to account for upstream methane leaks associated with natural gas consumed in the electricity sector, as CH4 is a potent greenhouse gas. However, rather than again calculating the annual change in CH4 leaks, the authors calculate the total annual CH4 emissions due to methane leaks associated with power-sector gas consumption. They thus subtract the full 50 million tons of CO2-e associated with total CH4 leaks from the annual net changes in CO2 emissions to arrive at a net savings of 4 million tons, as depicted in Exhibit 3 (note: the rounding errors apparent in these calculations are not explained, as 80-50-27 = 3 not 4).

In communications with the editors of this site, the authors report that the annual change in CH4


calculations.

Either way, counting only the assumed methane emissions attributable to the incremental natural gas consumption associated with the additional displacement of coal-fired electricity in 2012, rather than the assumed methane leakage for the entire US natural gas power generation fleet, results in a much smaller methane offset than you claim. That leaves a sizeable net emissions reduction benefit for gas, even if you assume that it also displaced a bit of hydro and nuclear power.

Do you have any analysis on Black Carbon reductions when switching from coal to natural gas?

Black carbon is one of the most potent greenhouse forcing elements and coal is a major source. Natural gas supplies virtually none to the atmosphere, with the exception of flaring activities (which need to be curtailed for multiple reasons).arthritis, constipation, diarrhea, hypertension, obesity, stomach disorders, and many other conditions. However, controlled studies never demonstrated reliability, and some studies found it highly unreliable [2-5]. For example, one study found that white cells from allergic patients reacted no differently when exposed to substances known to produce symptoms than when exposed to substances to which the patients were not sensitive [6]. Government regulatory actions [7-10] and unfavorable publicity have almost driven cytotoxic testing from the health marketplace. But a few practitioners still perform it, and many use similar "food sensitivity" tests.

ELISA/ACT Testing

Another test claimed to locate "hidden allergies" is the ELISA/ACT, developed by Russell Jaffe, M.D., Ph.D., and performed by Serammune Physicians Lab (SPL), of Reston, Virginia, which Jaffe directs. According to an SPL brochure:

When we think of allergies,


start with a bipartite quantum correlated state and by allowing one of the subsystem to interact with an environment the bipartite quantum state transforms to a zero discord state. This may be called as the complete erasure of quantum correlation under local operation. In this paper, we show that quantum discord is not just an informational resource but it is a physical one. We prove that whenever there is a change in quantum correlation that should be accompanied by entropy generation in the system and the environment. We also show that the Landauer erasure can be obtained from our entropic bound. Further, we show that any positive creation of quantum correlation must be at least equal to the negentropy of the combined system and the environment. Our resultsis the partition function. We can imagine that $\rho_B=  \mbox{Tr}[\rho_{AB}]$ for some density operator on ${\cal H}_{AB}$. During the interaction of system and bath, the increase in the energy of the bath is $\Delta E_E = \Delta E
= \mbox{Tr}[\rho_E' H_E] -
\mbox{Tr}[\rho_E H_E]$ and one can also see that the change in the entropy of system $B$ and $E$ satisfy $\Delta S_B + \Delta S_E \ge 0$ [@partovi]. Conservation of energy requires that $\Delta E_B + \Delta E_E =0$. In particular, if the initial state of $AB$ is uncorrelated, i.e., $\rho_{AB} = \rho_A \otimes \rho_B$, then $\Delta D(A:B) =0$. Using $\Delta S_{AB} \ge \Delta S_B$ and our bound (8) we have $\Delta E \ge k T S(\rho_B)$ which is precisely the well known Landauer’s erasure principle. If


we have $|\Psi\rangle_{AB} \langle \Psi | \otimes |E \rangle_{E} \langle E | \rightarrow
\mathbb{I}_A \otimes U_{BE} |\Psi\rangle_{AB} \langle \Psi | \otimes |E \rangle_{E} \langle E | (\mathbb{I}_A \otimes U_{BE})^{\dagger}$ The pure state transformation for the quantum bleaching process is given by $$\begin{aligned}
|\Psi\rangle_{AB} |E \rangle_{E} & \rightarrow & (\mathbb{I}_A \otimes U_{BE}) |\Psi\rangle_{AB} |E \rangle_{E}  \nonumber\\
& = & \sum_{jk} \sqrt{\lambda_j p_k}|a_j \rangle_A |k \rangle_B \otimes (|b_j \rangle |q_k \rangle)_E, \nonumber\\\end{aligned}$$ where we have used the hiding map $|b_j \rangle_B | E \rangle_{E} \rightarrow
\sum_{k} \sqrt{p_k} |k \rangle_B \otimes (|b_j \rangle |q_k \rangle)_E $ (up to adding zero vectors in the environment Hilbert space) [@sam]. The quantum bleaching process completely decorrelates the system $AB$. In this process, the change in the quantum correlation is $D_B(\rho_{AB}) - D_B(\rho_{AB}') = S(\rho_B)$ as theInt. J. Theor. Phys. [**26**]{}, 523 (1987).

S. Lloyd, Phys. Rev. A [**56**]{}, 3374 (1996).

M. B. Plenio and V. Vedral, Cont. Phys. [**39**]{}, 431 (1998).

V. Vedral, Proc. Roy. Soc. (London) [**A 456**]{}, 969 (2000).

A. K. Rajagopal, R. W. Rendel and S. Abe, AIP Conference Series, [**643**]{}, 47 (2002).

C. H. Bennett, G. Brassard, C. Cr[é]{}peau, R. Jozsa, A. Peres, and W.K. Wootters, Phys. Rev. Lett. **70**, 1895 (1993).

C. H. Bennett and S. J. Wiesner, Phys. Rev. Lett **69**, 2881 (1992).

A. K. Pati, Phys. Rev. A **63**, 014302 (2000).

C. H. Bennett, D. P. DiVincenzo, P. W. Shor, J. A. Smolin, B. M. Terhal, and W. K. Wootters, Phys. Rev. Lett. **87**, 077902 (2001).

L. Rio, J. Aberg, R. Renner, O. Dahlsten, and V. Vedral, Nature [**474**]{}, 61 (2011).

L. Henderson and V. Vedral,


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            val size = method.instructions.size()
            "$type method ${method.name} last 100:\n" +
                method.cloneWithInsnRange((size - 100) until size).toAsmString()
        }
    }

    companion object : AsmToBinary() {
       Living with MS: Keep Your Self-Image Well-Polished

People with more advanced multiple sclerosis (MS) may begin to question their value to themselves and others. They may start to lose sight of who they are and what they have to offer as the disease takes its toll in so many different ways.

You’re made up of many parts — you have qualities, interests, abilities, and quirks that you’ve acquired over a lifetime. Even though MS may have affected significant areas of your life, chances are high that those unique parts of you are still there. Your challenge, then, lies in figuring out new ways to engage those special parts of you.

If you’re having trouble getting started, have a heart-to-heart with your closest family members, friends, and colleagues. They’ll be happy to


the humidity controlling means (73), this makes it possible to reduce the water vapor pressure of the outside air, and the input of the pressure increasing means (50) can be reduced to a further extent. As a result, it becomes possible to further improve efficiency.
Further, if various types of waste heats can be utilized in the heat exchanger (7b) of the humidity controlling means (73), this makes it possible to make effective utilization of energy.I deserve") While there's nothing inherently wrong with all of this - and these things may all be accurate - aren't they just a bit...well...easy?

I don't have to go real deep into Jesus to do any of these things - how did that one commercial put it - image is everything.

Ponder Louie's thought with me - if we go deep into Jesus, the "Christian" in us will be obvious. Not based on t-shirts and cute answers, but based on a life that's been transformed by an all powerful, all knowing God who loved us way before we even gave Him a second thought. Our lives will begin to reflect a faith in God that doesn't change with our moods, that isn't shaken by things that used to put


our day into a tailspin.

It is then - and only then - that those around us will KNOW something has changed. Not because of what they see on the outside, but what they see going on inside of us. It will be evident in our eyes. That is when God will truly be gorified by our lives.

What we put into our lives in an attempt to satisfy ourselves is what our lives naturally glorify.

If I think money will satisfy - I'll bring glory to a "succesful" business. If I think another person will satisfy me - I'll bring glory to that person. If I think possessions will satisfy me, I'll fill my life with the latest and greatest - and glorify those things. If it's recognition - I'llof that rule says, "Applicants' publications must be editorially independent of any institution, foundation or interest group that lobbies the federal government, or that is not principally a general news organization."

"If Breitbart wishes to take steps to meet those requirements, the Committee will reopen its review," Lytle said.

The committee's primary concern, rather than its generally pro-Trump stance, appears to be Breitbart's ties to Rebekah Mercer, whose family partly owns the outlet, as well as the Government Accountability Institute, a conservative nonprofit that was co-founded by former Breitbart chairman and current White House strategist Steve Bannon.

Mercer, whose father Robert is a wealthy hedge fund manager and prominent Republican donor, is the chairwoman of GAI's board of directors.

The group's other founder, Peter Schweizer, is a senior editor-at-large at Breitbart News.

In


me they believe two dozen animals died in the fire at Second Chance Wildlife Sanctuary, but that’s just an early estimate. @WESH pic.twitter.com/hBzB6OpTiJ — Alex Villarreal (@AlexvWESH) February 4, 2019

Orange County Fire Rescue officials said in a series of tweets that the owner of the animal rescue was asleep in an upstairs bedroom when he was awakened by peacocks squawking.

Neighbors called 911 as the homeowner and sanctuary founder escaped, fire officials said. Officials said he was able to save some of the animals.

Firefighters were able to get the fire out in about 30 to 40 minutes, but the home, which is also the owner's wildlife sanctuary, was destroyed.

Among the animals killed were dogs, cats, snakes and several giant tortoises.

Fire rescue officials said they don't believe any dangerous animals502 and 29?
14558
Calculate the common denominator of 67/1782 and 59/17820.
17820
Find the common denominator of -23/11 and -39/19163.
210793
Calculate the least common multiple of 64847 and 133.
453929
Calculate the lowest common multiple of 4235 and 1936.
67760
Find the common denominator of 7/3720 and -89/7440.
7440
Find the common denominator of -39/687974 and -46/6573.
2063922
Calculate the common denominator of -29/2064 and -109/185760.
185760
Find the common denominator of 47/12 and 51/30368.
91104
Find the common denominator of -157/6840 and -89/61560.
61560
What is the common denominator of -187/2105580 and -1/42?
14739060
Calculate the common denominator of -61/80 and -41/5290.
42320
What is the smallest common multiple of 74367 and 996?
24689844
What is the lowest common multiple of 12696 and 12696?
12696
What is the lowest common multiple of 615 and 3701?
2276115
What is the lowest common multiple of 24 and 116716?
700296
Calculate the least common multiple of 21196 and 11.
233156
Calculate the


the United States; crises over a neoliberal educational regime whose defining feature appears to be the civic and democratic demoralization of America's public schools; and finally, crises over a combined sense of hopelessness and what might be called outrage fatigue. A rapid intensification of these political and cultural contradictions seems to be the hallmark of our era.[1](#Fn1){ref-type="fn"}

On the educational front, teacher strikes in Arizona, West Virginia, Kentucky, Oklahoma, Colorado, North Carolina, and in the city of Chicago, among other locales, speak at once to the shameful conditions that teachers face and to the hope that their underlying causes may soon be addressed. From a paradigmatic standpoint, it seems as if the very purposes of education that neoliberalism has imposed upon the nation's schools in the last few decadesthat the book is organized according to the jeremiad's three-part thematic structure. I adopt this format because the telos, or end-in-view, of Jefferson's revolutionary theory recapitulates, in both substance and form, this uniquely American form of rhetoric.

As Sacvan Bercovitch, David Murphy, David Howard-Pitney, and George Shulman have articulated, all types of jeremiadic texts---from the speeches of Jonathan Edwards and Frederick Douglass to Eugene Debs and Martin Luther King---partake of the same thematic structure, despite other differences in moral and ideological substance.[15](#Fn15){ref-type="fn"} The structure of the Puritan rhetorical trope unfolds in three sequences. In the first sequence, the speaker or writer reminds their audience about the rich significance and promise of their agreed-upon social covenant. In the second sequence---the declension---the speaker excoriates congregants for having so deplorably lost sight


revolutionary about the American Revolution. This final section of the book tells a story about what it would mean to recover these values and to embark upon a journey of moral renewal along several fronts: educationally, politically, and culturally.

The paradigmatic analysis here is indebted to many authors, below I name a few. Thomas S. Kuhn's *The Structure of Scientific Revolutions*. Chicago: University of Chicago Press, 1996 helps us to map structural transformations in many arenas. Kuhn's insight that paradigm shifts historically have occurred when "anomalies" and "contradictions" begin to accumulate within any given explanatory model/paradigm, suggests that we are presently on the cusp of such a transformational shift. For a much needed account of how the American warfare state is destroying the very conditions that make democracy possible,RIKERS ISLAND, N.Y.—On Christmas, the dinner menu at one of the nation’s most notorious jail complexes will include roast beef au jus, baked potatoes, whole-wheat bread and mixed vegetables. But there won’t be Christmas cookies for dessert.

“The carrot cake is the pièce de résistance,” said E. Glenn O’Connor, the New York City jail system’s director of nutritional services.

Paris has croissants. Belgium has waffles. And Rikers Island has carrot cake. The spiced loaf is the jail’s most famous food and the only dessert served on holidays.

The jail’s more than 50-year-old bakery produces about 2,500 loaves annually, resulting in 62,500 slices served (without frosting) on occasions including Thanksgiving, Christmas and the end of Ramadan.

“It’s synonymous with Rikers,” said Mr. O’Connor, whose prior jobs involved feeding people in other captive situations,


   fd >> temp;
    A[i].setPrice(temp);
    fd >> temp1;
    A[i].setCurrency(temp1);
}

after little test i figured out that it crashes then code tries to set "brand" variable. What's the problem?

A:

Array dimensions must be known at compile-time, so:
C A[n];

is wrong.
GCC supports variable-length arrays as a non-standard extension but, even if you're accidentally using them, your loop assumes n == 3 with no apparent indication that this is necessarily true.
Instead, use a vector:
std::vector<C> A(n);

and iterate over it properly:
std::vector<C>::iterator it = A.begin(), end = A.end();
for ( ; it != end; ++it) {
   // your for loop stuff with *it
}

or, in C++11:
for (auto& a : A) {
   // your for loop stuff with a
}

just to get the shapes and patterns in my head and under my fingers. Today, though, it was time to really roll up my sleeves and start digging.

The first movement, the Prelude, is four straight pages without a rest or a pause. That’s not the hard part- I can make room for breaths where I want them. The most difficult thing is organizing how to work on this sea of notes, so my first step today was simply to demarcate the sections of the piece. I pulled out my pencil and gave myself rehearsal letters where each new pattern begins. Now I can easily focus on a four to eight bar chunk, and can give myself permission to jump between sections as they relate to each other, rather


to sleep myself. She wiggled and kicked and chattered until, exhausted and crabby, I got up and headed to the couch to try to grab an hour of sleep before a busy day. Twenty minutes later I felt a disturbance in my blankets, and found her trying to squeeze in between my feet again.

I was angry, but I did not yell angrily. Rather, I intentionally raised my voice and made it sound angry in a calculated way. I wanted her to obey for a change.

“Zoe,” I said loudly and sharply, “go back to BED!”

She dissolved into pathetic tears of hurt and betrayal.

What could I do? I pulled her in under the covers and snuggled with her until her weeping stopped. I told her that I loved her allran an eighth of a mile to a residence.

A recently released laboratory report from the California Department of Food and Agriculture positively identified the bees as Africanized, known in the Hollywood movies as "killer bees."

The Africanized bees may have come from Arizona, Texas, Florida or southern California, Mussen said. Migratory beekeepers from all over the country truck in their bees to pollinate California's 800,000 acres of almonds, located in the Central Valley from Butte to Kern counties. Each acre requires two bee colonies for pollination.

Africanized bees swarm more often their cousins, the European honey bee, the most common bee in the United States.

"The attack is troubling but I doubt there are any more Africanized honey bee colonies swarms in that valley," Mussen reiterated. "Otherwise, more people would have


nutrition and health. Dietary diversity, defined as the number of different food groups consumed over a given reference period, has been identified as a useful measure for overall quality and nutrient adequacy of the diet that may influence blood formation. The dietary diversity score (DDS) is a recommended valid dietary assessment indicator that has been shown to reflect micronutrient intake among young children \[[@CIT0010]--[@CIT0012]\]. Consumption of foods from at least four food groups has been associated with a high likelihood of a child consuming at least one animal-source food and at least one fruit or vegetable, in addition to a staple food and, has been used to classify diets of children from developing countries \[[@CIT0013],[@CIT0014]\]. Furthermore, dietary diversity is considered to be a key indicator in assessing theaccess, utilization and quality of diet of individuals or household \[[@CIT0015]\].

In Ghana, where anaemia is of public health significance, very little is documented regarding the contribution of dietary factors to the haematological status of children. The effect of dietary diversity on blood biomarkers may be significant, but the evidence is limited. Furthermore, an association between dietary diversity and haematological status may be complicated by other factors including malarial infection and household socioeconomic status. This study therefore sought to determine the independent contribution of dietary diversity to the prevention of anaemia in children aged 6--59 months whilst controlling for potential confounding factors. We hypothesized that consumption of diversified diets would be associated with reduced prevalence of anaemia compared to nutrient-poor diets.

Subjects and methods {#S0002}
====================

Study area {#S0002-S2001}
----------

The study covered all the


probability proportion to size (PPS) method \[[@CIT0016]\]. Households were then selected from a sampling frame using a random systematic method.

Data collection {#S0002-S2003}
---------------

Study participants were then interviewed face-to-face by the investigators. Within each selected household, the caregiver responded to questions on anaemia prevention and treatment and expressed her knowledge and practices on anaemia. A pre-tested questionnaire was used to collect information including socio-demographic, infant and young child feeding (IYCF) practices, maternal knowledge, attitude, and practices on iron-rich foods, prevention and treatment of anaemia and child morbidity.

Independent and dependent variables {#S0002-S2004}
-----------------------------------

The main outcome variable for this study was the prevalence of anaemia (Hb less than 11 g/dl). The independent variables were maternal, child and household characteristics, malarial infection, and child dietary intake. A brief description of main independent and dependent(1.02, 3.18)\*1.4 (0.89, 2.14)1.5 (1.05, 2.11)\*Flush toilet0.8 (0.38, 1.63)1.2 (0.67, 2.06)1.0 (0.63, 1.53)Pit latrineReferenceReferenceReference**Fever in the past two weeks?**   NoReferenceReferenceReferenceYes2.9 (1.45, 5.95)\*\*1.40 (0.92, 2.12)1.7 (1.20, 2.45)\*\***Frequency of ANC visits**   0--31.7 (0.80, 3.73)1.41 (0.82, 2.43)1.5 (1.01, 2.39)\*At least 4ReferenceReferenceReference**Place of delivery**   Home delivery1.9 (1.08, 3.26)\*1.2 (0.77, 1.73)1.4 (1.04, 2.0)\*Institutional deliveryReferenceReferenceReference**Birth interval in months**   \> 24ReferenceReferenceReferenceUp to 242.5 (1.17, 5.39)\*\*1.7 (1.02, 2.93)\*1.9 (1.20, 2.84)\*\*[^1][^2]

Discussion {#S0004}
==========

The study is the first to investigate the potential role dietary diversity plays in haematological status of children using a nationally representative sample in Ghana. The analyses sought to assess the association between dietary diversity to haematological status of children aged 6--59 months whilst controlling for potential confounding factors including malarial infection.

The most consistent determinants of anaemia were child's age, continued breastfeeding, poverty, having fever, anaemic mother, birth interval ≤ 24 months, home delivery and


having no access to toilet facility. Genetic characteristics and micronutrient interactions may impair normal haemoglobin synthesis but these were not assessed in this survey.

Prevalence of anaemia {#S0004-S2001}
---------------------

The prevalence of anaemia among children aged 6--59 months was 66.8%. Anaemia is a public health problem when more than 5% of the population is anaemic, a significant public health problem in need of immediate action when prevalence exceeds 20%, and a severe public health problem when prevalence exceeds 40% \[[@CIT0018]\]. The survey findings corroborate past research that in developing countries, anaemia affects 46--66% of children aged under five years \[[@CIT0018]\].

Most of the children in this study had anaemia of mild to moderate severity with very few being severely anaemic. According to the WHO, the most common cause of high prevalence of anemiamight constrain families to access available health services such as antenatal care, decent toilet facilities and the power to purchase diversified and nutrient rich foods, all of which are risk factors to anaemia.

Stunted children were more likely to be anaemic than their counterparts. This finding is similar to studies conducted in many countries including Ethiopia, Bangladesh, Brazil and Burma \[[@CIT0003],[@CIT0004],[@CIT0023],[@CIT0027]\]. The reverse equally holds whereby anaemic children are more likely to be undernourished \[[@CIT0004]\] because a low hemoglobin level negatively affects linear growth \[[@CIT0047]\].

Consistent with other studies \[[@CIT0023],[@CIT0046]\], maternal anaemia was associated with anemia in the children. This association could be partly be explained on the basis that all family members shared the same socioeconomic environment \[[@CIT0023]\].

Our results also showed that prevalence of anaemia among children whose mothers


caused by changes to the gastrointestinal epithelium of infected children can significantly contribute towards anaemia.

The set of predictors of anaemia identified in this study could explain only 17% of the variation in anaemia in the population, which suggest many more factors other than those measured in this study are responsible for anaemia.

Conclusion and recommendations {#S0006}
==============================

The prevalence of anaemia was of public health significance according to the WHO cut-off points. In bivariate analyses, minimum dietary diversity was positively associated with mean Hb concentrations among children 6--23 months but it was negatively associated with Hb concentrations among children 48--59 months. Similarly, minimum dietary diversity was weakly associated with reduced prevalence of anaemia only among children 6--23 months although this relationship disappeared in the multiple regression model.

The current study showed that factors other thanhis predecessor in interest knew or should have known of the claim of the United States.1

6
Based on section 2409a(f), the defendants moved the district court for summary judgment, and plaintiffs moved for summary judgment on the merits.  The district court denied defendants' motion but granted plaintiffs' motion.  On appeal, we reversed the district court's entry of summary judgment and, on remand, directed the district court to determine whether erroneously excluded evidence concerning the original deed was otherwise admissible. Amoco Production Co. v. United States, 619 F.2d 1383, 1392 (10th Cir.1980) (Amoco I ).2   If the evidence was admissible, we directed the district court to determine if the original deed contained a reservation of fifty percent of the mineral rights.

7
On remand, the district court held


However, in that case we were reviewing the disposition of motions for summary judgment and, in particular, whether the 1957 quitclaim deed gave constructive notice to the plaintiffs so as to bar their suit.  We were never asked to address the question of whether there was sufficient evidence to conclude that the plaintiffs had actual knowledge of the United States' claims.  It was not until additional evidence was submitted on remand that the district court had an adequate opportunity to delve into the subjective knowledge of the parties and thereby learn whether plaintiffs or their predecessors had actual knowledge of the United States' claim to the minerals.  In light of the evidence heard on remand, the district court reconsidered whether section 2409a(f) would bar theagency and the United States had an interest in title.  Record, vol. 11, at 8-11.  We agree with the conclusions of the district court.   See, e.g., Freeling v. Federal Deposit Insurance Corp., 221 F.Supp. 955, 956 (W.D.Okla.1962), aff'd, 326 F.2d 971 (10th Cir.1963) (control of corporation by Congress leads to conclusion FDIC is a federal agency of the United States)

7
 The district court's reference to Federal Rule of Civil Procedure 13(d) and its argument that plaintiffs are somehow enlarging their substantive rights against the United States, record, vol. 1, doc. 135, at 7-8, are not well founded.  First, Rule 13(d) concerns counterclaims against the United States.  The present matter involves a counterclaim by the United States.  Second, the quiet title issues


Q:

Get full link from menu item field type

I am developing my own slideshow component and module for Joomla. The component is used to select the slides along with captions and links etc. The module shows the slides.
In the component, for each slide I have enabled the option to add a link to each slide. The field type that I have used is the menu item field type http://docs.joomla.org/Menuitem_form_field_type
This seems to add the menu item id to the database for that particular slide.
My question is; how do I take this menu item id and then in the module use it to get the full menu item link? I will understand that I will probably have to search through the database to find the right menu item and then findimportant findings that could help victims of post-traumatic stress disorder (PTSD).

“Computational models make it much easier to study the brain because they can effectively integrate different types of information related to a problem into a computational framework and analyze possible neural mechanisms from a systems perspective. We simulate activity and test a variety of “what if” scenarios without having to use human subjects in a rapid and inexpensive way,” Li said.

From previous experiments, scientists have found that fear can subside when overcome with fear extinction memory, but it is not permanently lost. Fear extinction is a process in which a conditioned response to a stimulant that produces fear gradually diminishes over time as subjects, such as rats in auditory fear experiments, learn to disassociate a response from a


stimulus. One theory has concluded that fear extinction memory deletes fear memory, and another concluded that fear memory is not lost, but is inhibited by extinction memory as fear can recover with the passage of time after extinction.

“Fear extinction memory is not well understood, and our computational model can capture the neuron response well in rat during auditory fear conditioning with a mixture of mathematics and biophysical data,” said Li. “Our main contribution is that our model predicts that fear memory is only partially erased by extinction, and inhibition is necessary for a complete extinction, which is a reconciliation of the erasure and inhibition theories. Furthermore, our model shows that the inhibitory connection from interneurons to pyramidal cells serve as an important site for the storage of extinctionof action.
The plaintiff's brief does not argue the trial court's action in sustaining the demurrer as to the cause of action for slander and therefore it will not be considered here. See Rule 8a 2(3), Revised Rules of the Supreme Court, 1974.
The judgment of the District Court was correct and is affirmed.
AFFIRMED.


The anatomy of the radial side of the thumb: static restraints in preventing subluxation and rotation after injury.
This study sought to define the anatomic variations of the radial side of the thumb metacarpophalangeal joint and to assess the contributions of the radial structures to stability. In Part I, the radial side of the thumb metacarpophalangeal joint was studied in 31 cadavers, showing that the extensor pollicis brevis insertion was variable. In Part II, 13 additional hands were studied to evaluate the static restraints to rotation and subluxation, showing that variability in the amount of volar subluxation and pronation was possible in the intact thumb. This study showed that the radial collateral ligament and extensor pollicis brevis capsule collectively contribute to stability against rotation and volar subluxation. We foundaligned with each other, a highly accurate alignment is required, which causes the generation of many rejected products to lower the yield.
Accordingly, an object of the present invention is to provide a semiconductor device capable of being mass-produced at a low cost, a method for producing the same, a carrier substrate used therefor and a method for producing the same by solving the above-mentioned problems in the prior art to simplify the manufacturing process.
According to the present invention, there is provided a semiconductor device comprising: a semiconductor element having at least one signal electrode and at least one ground electrode; a mounting part metallic film having a bottom area on which the semiconductor element is mounted and a stepped area located at a periphery of the bottom area


an array of strings, then your search would work. An alternate approach might be:
function found(gridData, sessionStorageData) {
  for (o in sessionStorageData) {
    if (sessionStorageData[o].catalogNumber == gridData.catalogNumber) {
      return true;
    }
  }
  return false;
}

if (!found(gridData.catalogNumber, sessionStorageData )) {
    sessionStorageData.push(gridData);
    sessionStorage.setItem('people', JSON.stringify(sessionStorageData));
}

Solution #2
An even better solution might be to map your array of objects into an array of strings.
var catalogNumbers = sessionStorageData.filter(function(obj){ return !!obj }).map(function(obj) { return obj.catalogNumber; } );
if (jQuery.inArray(gridData.catalogNumber, catalogNumbers ) === -1) {
    sessionStorageData.push(gridData);
    sessionStorage.setItem('people', JSON.stringify(sessionStorageData));
}

in 2004, after the Mexican Football Federation (FMF) decided to reduce the number of participants in the First Division to 18 clubs. The FMF bought the Gallos Blancos franchise for the lack of transparency regarding the origin of its financial resources and decided to disappear it.

Ascenso MX Teams
After original La Piedad team was moved to Querétaro, a new franchise arrived to the city: Tampico Madero adopted the name and colors of Reboceros on Invierno 2002 tournament. The new La Piedad franchise arrived to the tournament final against Irapuato, finally, the Irapuato won the championship, in January 2003, La Piedad was moved to Celaya and was renamed as Cajeteros del Celaya.

In 2004, Guadalajara moved its reserve squad to La Piedad and was named as Chivas La Piedad, however the


CFA Society Singapore

Volunteer

The Society’s Board and leadership team is working to revitalise our pursuit of the CFA Singapore Mission, which is “to lead the investment profession by promoting the highest standards of ethics, education, and professional excellence for the ultimate benefit of society.”

Members and candidates are encouraged to get involved with one of the society's many efforts as this is a member-driven society and volunteering is a great way to “give back”.

To find out more about each committee, please click on the following links:INTRODUCTION
============

Endometrial cancer is the most common gynecologic malignancy in women in the United States \[[@B1]\]. In 2009, an estimated 42,160 new cases and 7,780 cancer-related deaths were anticipated \[[@B1]\]. Certain clinical/pathologic characteristics have been shown to be significant predictors of outcome such as tumor grade. The 5-year survival rate for women with stage IA grade 1 cancer exceeds 90%, whereas it is only 69% for women with stage IA grade 3 cancer \[[@B2]\]. In addition to grade, the histopathological types of the endometrial cancer influence the outcome. For example, patients with uterine papillary serous carcinomas (UPSC) or carcinosarcomas that was termed malignant mixed mullerian tumor are thought to have a worse outcome than those with endometrioid adenocarcinomas of the uterus. The poor outcome in these patients is often


Sunday, 29 November 2009

White Christmas

When I saw the challenge at Secret Crafter which this week is Christmas trees I just knew I had to use another stamp from My Lovely as Tree set from Stampin'up which were still sitting on my desk. This card also fits the challenge at Daring Cardmakers which this week is "I'm dreaming of a White Christmas" which means Christmas cards that are mainly white with just a hint of colour.by the nuclear transport receptor, transportin1^[@CR17]^. FUS is also involved in RNA metabolisms including transcription, pre-mRNA splicing, mRNA transport, post-translational modification and miRNA biogenesis^[@CR18]^. Recently, increased FUS protein levels in FTLD-brain samples were reported^[@CR19]^. In addition, it was also shown that four mutations in the 3′ untranslated region (UTR) of *FUS* that were identified in ALS patients caused FUS overexpression, indicating the pathological signature of wild-type FUS overexpression in not only FTLD but also some cases of ALS^[@CR19],[@CR20]^. Consistent with these findings, cell and rodent models harboring wild-type human *FUS* (*hFUS*) were established and they support the conclusion that wild-type FUS accumulation, but not the mutant-form of FUS, is sufficient to cause neurodegeneration and neuronal cell death^[@CR21]--[@CR23]^.

Polyglutamine (polyQ) disease is a collectively named neurodegenerative disorder including Huntington's disease,


molecular chaperones^[@CR40],[@CR41]^.

In the present study, we therefore examined the effect of several proteins including molecular chaperons on the aberrant eye morphology phenotype induced by wild-type *hFUS*. By screening, we have found that the co-expression of nucleophosmin--human myeloid leukemia factor 1 (NPM*-*hMLF1) fusion protein could suppress the aberrant eye morphology phenotype induced by *hFUS*. Fusion protein NPM-hMLF1 is produced by the t(3;5) (q25.1;q34) chromosomal translocation, associating with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML)^[@CR42],[@CR43]^. NPM is a nucleolar localized non-ribosomal RNA binding phosphoprotein that functions as a shuttle protein by transporting ribosomal ribonucleoproteins between the nucleus and the cytoplasm during the assembly of ribosomes^[@CR44],[@CR45]^. hMLF1 protein mainly localizes in the cytoplasm, while its fused form with NPM mainly localizes in the nucleus^[@CR43]^. The driving of *hFUS* expression atin the posterior region to MF in the eye imaginal discs (Fig. [3h](#Fig3){ref-type="fig"}). No such signal was detected in eye imaginal discs of the control flies expressing *lacZ* (Fig. [3d](#Fig3){ref-type="fig"}). Merged images showed that NPM-hMLF1 signals mainly co-localized with 4′ 6-diamidono-2-phenylindole (DAPI), especially in the DAPI faint region (Fig. [3j](#Fig3){ref-type="fig"}). The data suggest that NPM-hMLF1 mainly localizes in nucleoplasm of eye imaginal disc cells. However, since in some cells NPM-hMLF1 signals partially co-localized with cytoplasmic actin signals (Fig. [3k](#Fig3){ref-type="fig"}), we cannot exclude the possibility that some fractions of NPM-hMLF1 proteins also localize in cytoplasm.

hFUS appears to co-localize with NPM-hMLF1 mainly in nucleoplasm of eye imaginal disc cells {#Sec6}
-------------------------------------------------------------------------------------------

To confirm specificity of anti-hFUS IgG, we performed Western immunoblotting analysis with extracts of adult heads carrying *GMR*-*GAL4*/*Y*; *UAS*-*hFUS*/+. Two major bands corresponding to 83 kDa


feeding of MG132 from 5 μM to 10 μM inhibited both hFUS and caz protein degradation (Fig. [5d--f](#Fig5){ref-type="fig"}). The data suggest that the down-regulation of both hFUS and caz are mediated by proteasome-dependent degradation.

Co-expression of *NPM*-*hMLF1* recovered the hFUS protein level but not caz protein level {#Sec9}
-----------------------------------------------------------------------------------------

To examine the effect of co-expression of *NPM*-*hMLF1* on levels of hFUS and caz proteins at 28 °C, we performed Western immunoblotting analysis with extracts of adult heads carrying *GMR*-*GAL4*/*Y*; *UAS*-*hFUS*/*UAS*-*GFP* and *GMR*-*GAL4*/*Y*; *UAS*-*hFUS*/*UAS*-*NPM*-*hMLF1*. Expression of hFUS decreased caz protein level by 51 percent (Fig. [6a,c](#Fig6){ref-type="fig"}), which corelates with the eye phenotype (Fig. [2h--j](#Fig2){ref-type="fig"}). Co-expression of *NPM*-*hMLF1* increased hFUS protein level approximately two fold, but the decreased caz protein level was not recovered (Fig. [6a--c](#Fig6){ref-type="fig"}). The eye phenotype was suppressed under these conditions (Fig. [2k--m](#Fig2){ref-type="fig"}). These results indicate that co-expressiondead larvae (4/42) were observed in flies carrying *w*; *UAS*-*hFUS*/*UAS*-*GFP*; *D42*-*GAL4*/+ (n = 42). Eclosed adult flies (4/41), dead pharate adults (32/41) and dead larvae (5/41) were observed in flies carrying *w*; *UAS*-*hFUS*/*UAS*-*NPM*-*hMLF1*; *D42*-*GAL4*/+ (n = 41).

Discussion {#Sec12}
==========

In the present study, we observed a strong eye phenotype at 28 °C. Unexpectedly, the hFUS level decreased at 28 °C compared to 25 °C and this hFUS reduction was inhibited by feeding a proteasome inhibitor to flies. The data suggest that the strong eye phenotype at 28 °C is likely due to proteasome-dependent degradation of hFUS protein. Interestingly, co-expression of *NPM*-*hMLF1* suppressed the eye phenotype with the increase in hFUS protein level, but not caz. In addition, we also revealed that co-expression of *NPM*-*hMLF1* partially rescued pharate adult lethal phenotype induced by motor neuron-specific expression of *hFUS*, implying


of Urea soluble hTDP-43 protein in transgenic flies expressing wild-type *hTDP-43*^[@CR50]^. In contrast, inclusions containing hFUS are recovered in sodium dodecyl sulfate (SDS) fractions in tissues of human FTLD patients^[@CR10]^. Here, we observed a higher level of Sarkosyl soluble hFUS protein than that of Urea soluble hFUS protein in transgenic flies expressing *hFUS*, suggesting that hFUS is less insoluble than hTDP43 in *Drosophila* cells as observed with human FTLD patients. In addition, it was also reported that increasing the solubility of hTDP-43 protein by co-expression of *futsch* closely correlates with extension of life span and improvement of locomotive defects in flies expressing *hTDP-43*^[@CR50]^. Similarly to this report, we found that co-expression of *NPM*-*hMLF1* slightly increased the solubility of hFUS protein. Furthermore, eye phenotype and pharate adult lethal phenotypeDr. K. Ohno for establishing transgenic flies carrying the UAS-*NPM*-*hMLF1*, Dr. L. Lo Piccolo for advice in the protein solubility test. We thank the Bloomington *Drosophila* Stock Center and Kyoto Stock Center for fly lines. This study was partially supported by the JSPS Core-to-Core Program, Asia-Africa Science Platforms, the JSPS Program for Advancing Strategic International Networks to Accelerate the Circulation of Talented Researchers (Grant No. S2802), JSPS KAKENHI Grant Number 16K07346. We also thank Medical English Service for the English language review.

I.Y. performed the experiments. M.U. and Y.N. generated *hFUS* transgenic flies. I.Y., Y.A., Y.K., H.Y., I.M., T.M., M.U., Y.N., T.T. and M.Y. designed and analyzed the experiments. I.Y. and M.Y. wrote the paper. All authors reviewed the manuscript.

Competing Interests {#FPar1}
===================

The authors declare no competing interests.


and Human Services.

Extracurricular activities
Student groups and activities include art club, choir, community service club, debate club, drama club, Friendship News Network, the Leadership Criminal Justice Program, National Honor Society, robotics team, science club, student government association, world language club, and yearbook.

The Collegiate Academy teams, known as the Knights, compete in girls & boys basketball, baseball, cheer-leading, football, soccer, track and field, and volleyball.

References

External links
http://www.vppartners.org/portfolio/pdf/VPP_Friendship.pdf
http://www.friendshipschools.org
Friendship News Network

Category:Charter schools in the District of Columbia
Category:District of Columbia Public Schools
Category:Educational institutions established in 2000
Category:Public high schools in Washington, D.C.first two columns in the reverse order, i.e. the action of $\sigma\tau $, is easily obtained by reversing the roles of the indices $i\leftrightarrow i+m$. Hence, $$\sigma\tau\cdot {\mathbf{ev}}({\mathbf{c}})= {\mathbf{ev}}(\mu_{\overline{i_1}}\cdots \mu_{\overline{i_k}}{\mathbf{x}}).$$ where we use the notation $\bar{i}:=i+m \mod 2m$. One finally deduces $$\tau\cdot {\mathbf{ev}}({\mathbf{c}})= {\mathbf{ev}}(\mu_{\overline{i_1}}\cdots \mu_{\overline{i_k}}\mu_{+}{\mathbf{x}}).$$

\[unitfrieze\] The integral 2-friezes - are unitary friezes. Under the action of the dihedral group the friezes - produce 50 different friezes coming for the evaluation of the 50 clusters of the cluster algebra ${\mathcal{A}}_{{\mathcal{Q}}_2}\simeq {\mathcal{A}}(D_4)$. Consequently, is not a unitary frieze.

The formal frieze of width 2 is displayed in Example \[ClustSix\]. We construct the fragments of frieze - as image of the map ${\mathbf{ev}}$ (with the convention that the two first columns of the fragment contain the initial cluster variables $(x_1,\ldots, x_{4})$).

The fragment


integral 2-friezes in bijective correspondence with a set of combinatorial objects similar to triangulations? This would give an analog of the property (CC2) mentioned in the introduction.

The second type of constructions introduced in the paper comes from the geometric interpretation of 2-friezes in terms of polygons in the space. It would be interesting to determine whether the set of unitary friezes is stable under the operations , , .

In a more algebraic setting, let us denote by ${\mathcal{F}}_m$ the set of integral closed 2-friezes of width $m$, and let us consider the vector space of basis vectors $\lbrace {\mathcal{F}}_m, m\geq 1\rbrace $ over an arbitrary field $K$ $${\mathbb{A}}=\bigoplus_{m\geq 1}K {\mathcal{F}}_m.$$ The operation gives a structure of associative algebra on ${\mathbb{A}}$. This algebra is graded by $\deg(F)=m-1$ for $F\in{\mathcal{F}}_m$.format is not supported by the device. Try changing the <paramref name="Frequency" /> and <paramref name="Flags" /> parameters.</exception>
        /// <exception cref="Errors.Memory">There is insufficient memory.</exception>
        /// <exception cref="Errors.No3D">The device has no 3D support.</exception>
        /// <exception cref="Errors.Unknown">Some other mystery problem!</exception>
        /// <remarks>
        /// <para>This function must be successfully called before using any sample, stream or MOD music functions. The recording functions may be used without having called this function.</para>
        /// <para>Playback is not possible with the <see cref="NoSoundDevice"/> device, but it does allow the use of "decoding channels",


  /// Changes the device that a stream, MOD music or sample is using.
        /// </summary>
        /// <param name="Handle">The channel or sample handle... only HMUSIC, HSTREAM or HSAMPLE are supported.</param>
        /// <param name="Device">The device to use...0 = no sound, 1 = first real output device.</param>
        /// <returns>If succesful, then <see langword="true" /> is returned, else <see langword="false" /> is returned. Use <see cref="LastError" /> to get the error code.</returns>
        /// <remarks>
        /// All of the channel's current settings are carried over to the new device,but if the channel is using the "with FX flag" DX8 effect implementation,
        /// the internal state (eg. buffers) of the DX8 effects will be reset. Using the "without FX flag" DX8 effect implementation, the state of the DX8 effects is preserved.
        /// <para>
        /// When changing a sample's device, all the sample's existing channels (HCHANNELs) are freed.
        /// It's not possible to change the device of an individual sample channel.
        /// </para>
        /// </remarks>
        /// <exception cref="Errors.Handle"><paramref name="Handle"


    /// <para>The actual volume level may not be exactly the same as set, due to underlying precision differences.</para>
        /// <para>
        /// This function affects the volume level of all applications using the same output device.
        /// If you wish to only affect the level of your app's sounds, <see cref="ChannelSetAttribute(int, ChannelAttribute, float)" />
        /// and/or the <see cref="GlobalMusicVolume"/>, <see cref="GlobalSampleVolume"/> and <see cref="GlobalStreamVolume"/> config options should be used instead.
        /// </para>
        /// </remarks>
        /// <exception/// On Linux, a "Default" device is hardcoded to device number 1, which uses the default output set in the ALSA config, and the real devices start at number 2.
        /// That is also the case on Windows when the IncludeDefaultDevice option is enabled.
        /// </para>
        /// </remarks>
        /// <exception cref="Errors.Device">The device number specified is invalid.</exception>
        public static DeviceInfo GetDeviceInfo(int Device)
        {
            if (!GetDeviceInfo(Device, out var info))


everything disappears.

That’s due to the corruption in your file and why I copied the floor plans to a new file.

Petec:

Does that mean my model is still corrupted?

Yes. Just changing its name doesn’t fix anything. Brussels sprouts are still Brussels sprouts even if you call them baby cabbages.are extracted from the highly-polarized mixture of water or polyhydroxy compound and polar extraction solvent into a low polar or nonpolar solvent by contacting the water or polyhydroxy compound-polar solvent mixture with the low polar or nonpolar solvent. The halogenated aliphatic and aromatic compounds and the low polar or nonpolar solvent are separated by physical means, e.g., vacuum evaporation. The polar and nonpolar solvents are recovered from recycling. The process can easily be designed for continuous operation. Advantages of the process include that the polar solvent and a major portion of the nonpolar solvent can be recycled, the petroleum products are reclaimable and the cost for disposing of waste containing polychlorinated biphenyls is significantly reduced. 1 fig.

A process for removing halogenated aliphatic and aromatic compounds, e.g., polychlorinated biphenyls,


through the reflux in molar excess to that required to react with ethylene, thereby reacting substantially all of the ethylene and recovering benzene as the principal overhead and ethyl benzene in the bottoms. 1 figures.

Aromatic compounds are alkylated in a catalytic distillation, wherein the catalyst structure also serves as a distillation component by contacting the aromatic compound with a C[sub 2] to C[sub 10] olefin in the catalyst bed under 0.25 to 50 atmospheres of pressure and at temperatures in the range of 80 C to 500 C, using as the catalyst a mole sieve characterized as acidic or an acidic cation exchange resin. For example, ethyl benzene is produced by feeding ethylene below the catalyst bed while benzene is conveniently added through the reflux in molar excessbenzene inlet is located near the upper end of the vessel; an olefin inlet is juxtaposed with said solid acidic catalytic material; a bottoms outlet is positioned near the bottom of said vessel for removing said cumene and ethyl benzene; and an overhead outlet is placed at the top of said vessel for removing any unreacted benzene and olefin.

Aromatic compounds are alkylated in a combination reactor/distillation column comprising a vessel suitable for operating between 70 C and 500 C and from 0.5 to 20 atmospheres pressure; an inert distillation packing in the lower one-third of said vessel; solid acidic catalytic material such as zeolites or an acidic cation exchange resin supported in the middle one-third of said vessel; and inert distillation packing in the upper one-third of said


and 1-methylallenyl combination reactions lead to benzene and methyl substituted benzene formation, while polycyclic aromatics are formed from cyclopentadienyl radicals and fused rings that have a shared C{sub 5} side structure. Naphthalene production through the reaction step of cyclopentadienyl self-combination and phenanthrene formation from indenyl and cyclopentadienyl combination were shown to be important in the flame modeling study. The removal of phenyl by O{sub 2} leading to cyclopentadienyl formation is expected to play a pivotal role in the PAH or soot precursor growth process under fuel-rich oxidation conditions.

Analysis of proteinases is accomplished using conventional amino acid containing aromatic amine substrates. Aromatic amines such as 4-methoxy-2-naphthylamine (4M2NA), 2-naphthylamine, aminoisophthalic acid dimethyl ester, p-nitroaniline, 4-methoxy-1-aminofluorene and coumarin derivatives resulting from enzymatic hydrolysis of the substrate couples with aromatic aldehydes suchis slowly removed. A recently constructed 50,000 Btu/hr staged combustor was used to study the chemistry of the nitrogen and aromatics. SRC II combustion was studied under fuel-rich, first-stage conditions at air/fuel ratios from 0.6 to 1.0 times stoichiometric. The chemistry of the fuel during combustion calls for further investigation in order to examine the mechanism by which HCN is evolved as a common intermediate for the formation of the nitrogen-containing gaseous combustion products. 25 references, 45 figures, 25 tables.

Sampling and analytical procedures were developed for determining the concentrations of polycyclic aromatic hydrocarbons in animal-exposure chambers during studies on exposure to diesel exhaust, coal dust, or mixtures of these two pollutants. Fluoranthene, pyrene, benzo(a)anthracene, chrysene, benzo(e)pyrene, benzo(k)fluoranthene, and benzo(a)pyrene were used as representative polycyclic aromatic hydrocarbons. High-pressure liquid


questions were answered regarding the addition of a biomass to ethanol facility to existing sugar mills. The focus of this work is on developing technology to produce ethanol and valuable by-products from bagasse. Three major areas are addressed, feedstock storage, potential by-products and the technology for producing ethanol from dilute ammonia pre-treated bagasse. Sugar mills normally store bagasse in a simple pile. During the off season there is a natural degradation of the bagasse, due to the composting action of microorganisms in the pile. This has serious implications if bagasse must be stored to operate a bagasse/biorefinery for a 300+ day operating cycle. Deterioration of the fermentables in bagasse was found to be 6.5% per month, on pile storage. This indicates that long term storage of adequate amountsof bagasse for year-round operation is probably not feasible. Lignin from pretreatment seemed to offer a potential source of valuable by-products. Although a wide range of phenolic compounds were present in the effluent from dilute ammonia pretreatment, the concentrations of each (except for benzoic acid) were too low to consider for extraction. The cellulosic hydrolysis system was modified to produce commercially recoverable quantities of cellobiose, which has a small but growing market in the food process industries. A spin-off of this led to the production of a specific oligosaccharide which appears to have both medical and commercial implications as a fungal growth inhibitor. An alternate use of sugars produced from biomass hydrolysis would be to produce succinic acid as a chemical feedstock for other conversions. An organism was


developed which can do this bioconversion, but the economics of

This invention relates to a compact and portable detection apparatus for nitro-aromatic based chemical compounds, such as nitrotoluenes, dinitrotoluenes, and trinitrotoluene (TNT). The apparatus is based upon the use of fiber optics using filtered light. The preferred process of the invention relies upon a reflective chemical sensor and optical and electronic components to monitor a decrease in fluorescence when the nitro-aromatic molecules in aqueous solution combine and react with a fluorescent polycyclic aromatic compound. 4 figures.

This invention relates to a compact and portable detection apparatus for ro-aromatic based chemical compounds, such as nitrotoluenes, dinitrotoluenes, and trinitrotoluene (TNT). The apparatus is based upon the use of fiber optics using filtered light. The preferred process of the invention relies upon ain nontraditional applications such as plastic fillers, metal matrix composites, refractories, and carbon adsorbents. Technologies to use beneficiated fly ash in these applications are being successfully developed. In the future, we will continue to refine the separation and utilization technologies to expand the utilization of fly ash. The disposal of more than 31 million tons of fly ash per year is an important environmental issue. With continued development, it will be possible to increase economic, energy and environmental benefits by re-directing more of this fly ash into useful materials.

The disposal of flue gas desulfurization (FGD) by-products has become a major concern as issues of emission cleansing and landfill costs continue to rise. Laboratory tests conducted at the Ohio State University have shown that dry FGD by-products possess certain