group, an aryl group, an alkoxy group, a substituted or unsubstituted amino group or a hydroxyl group. The substituted amino group is an alkylamino group, an arylamino group, a sulfonamido group, a carbonamido group, a ureido group, a urethane group, a carbamoylamino group or a sulfamoylamino group. R19 is particularly preferably a hydrogen atom or an alkyl group having from 1 to 10 carbon atoms.
R11 to R18, which may be the same or different, each represents a hydrogen atom or a substituent.
Examples of the substituents of R11 and R12 include the substituents described above for R19.
Examples of the substituent of R13 to R18 include an alkyl group (preferably having from 1 to 30 carbon atoms, more preferably from 1 to 20 carbon atoms, still more preferably from 1atoms, more preferably from 1 to 20 carbon atoms; the hetero atom is, for example, a nitrogen atom, an oxygen atom or a sulfur atom; specific examples include imidazolyl, benzimidazolyl, benzoxazolyl, thiazolyl, benzothiazolyl, pyridyl, furyl, piperidyl and morpholino). These substituents each may further be substituted.
Any of the substituents R13 to R18 may be combined to form a 5- or 6-membered alicyclic, heterocyclic or aromatic ring, provided that R16 and R17 are not combined to form an aromatic ring.
R11 and R12 each is preferably a substituted or unsubstituted alkyl group having from 1 to 20 carbon atoms or an aryl group having from 6 to 20 carbon atoms. R11 and R12 may combine with R13 or R14, respectively, to form a 5- or 6-membered alicyclic ring, for example, an


as a layer formed on a soda lime glass, an alkali-free glass or a transparent resin substrate. In the case of using a glass, the constructive material therefor is preferably an alkali-free glass so as to reduce the ion dissolved out from the glass. In the case of using a soda lime glass, the glass is preferably subjected to barrier coating with silica or the like. The thickness of the substrate is not particularly limited as far as the substrate can maintain the mechanical strength, however, in the case of using a glass, it is usually 0.2 mm or more, preferably 0.7 mm or more.
The anode may be prepared by various methods according to the material used and for example, in the case of ITO, the film isas a single layer of the above-described compound or mixture but also as a laminate structure including the compound or mixture. The thickness of the cathode may be freely decided depending on the material used, however, it is usually in the range of preferably from 10 nm to 5 xcexcm, more preferably from 50 nm to 1 xcexcm, still more preferably from 100 nm to 1 xcexcm. The cathode may be prepared by an electron beam method, a sputtering method, a resistance heating evaporation method or a coating method, and a sole metal may be deposited or two or more components may be simultaneously deposited. Furthermore, a plurality of metals may be simultaneously deposited to form an alloy electrode or an alloy previously prepared may be deposited. The


Q:

check permissions of directories in python

i want a python program that given a directory, it will return all directories within that directory that have 775 (rwxrwxr-x) permissions
thanks!

A:

Neither answer recurses, though it's not entirely clear that that's what the OP wants. Here's a recursive approach (untested, but you get the idea):
import os
import stat
import sys

MODE = "775"

def mode_matches(mode, file):
    """Return True if 'file' matches 'mode'.

    'mode' should be an integer representing an octal mode (eg
    int("755", 8) -> 493).
    """
    # Extract the permissions bits from the file's (or
    # directory's) stat info.
    filemode = stat.S_IMODE(os.stat(file).st_mode)

    return filemode == mode

try:
    top = sys.argv[1]
exceptSleep for cyclists: how to ensure you’re recovering properly

by Matt de Neef

We all know how important sleep is, not just for physical regeneration but for mental and psychological recovery as well. And when you're a cyclist – professional or otherwise – sleep plays an even more vital role than it might for the average person.

CyclingTips editor Matt de Neef spoke with Dr Shona Halson, Senior Physiologist at the Australian Institute of Sport (AIS), to find out what the research does and doesn't tell us about our requirements for sleep, and to get a few tips on how to ensure we're recovering effectively for that next ride.

At the most basic level, humans need sleep for mental and physical regeneration. If we don’t get enough sleep, our regular cognitive function


are fed, bathed, in bed; AND I actually have a
chat with the missus, it is 8PM.

Nick

Is recovery just about sleep (is this the only time hGH is released into the body)?
What about just lying down with the weight off your legs?
Besides the obvious things like stretching / massage / ice baths, I get the impression that during a stage race, for example, pro cyclists spend a lot of time off their feet, so whilst they are not getting the sleep time, their legs are recovering because they’re not walking around or fatiguing their legs / body like the average cyclist.

jules

Hinault used to have his soigneurs carry him up stairs!

velocite

Where did that tidbit come from Jules?

Emma

Really interesting. A lot of common sense in there I think as well. Ino way I can get a good night’s sleep that night, but I’m gathering that’s not so important, but it might be a very good idea to make sure I more sleep than my usual 6-7 hours in the lead up week.

700×23

So i can take HGH to augment sleep?

Sport Sleep Coach

Great read!! if people are interested in this topic, they should head over to our site and read through some of the blogs or just get in touch. We’ve got a lot of experience in the sport of cycling, having worked with the likes of Team Sky and British Cycling.http://www.sportsleepcoach.com


Introduction {#s0001}
============

Low temperature (LT) is one of the major abiotic stress factors that limit the growth, productivity and geographical distribution of agricultural crops,\[[@cit0001]\] including temperate cereals. Even in the established agricultural production areas, seasonal or episodic freezing events can lead to significant losses in yield and quality of wheat. Winter wheat with higher yield and quality potential has to withstand freezing temperatures during the winter. Currently, due to the increased necessity of feeding an ever-expanding human population, one of the main breeding efforts worldwide is the development of wheat cultivars with better adaptation to cold. Greater LT tolerance allows more flexible farm management, environmentally friendly production systems, lower herbicide costs and energy requirements and, finally, increased crop moisture utilization and productivity.\[[@cit0001]\] Identifying and understanding the genetic and molecularfrom approximately 100 mg leaf tissue, using Trizol (Invitrogen™) following the manufacturer\'s instructions. The concentration and quality of RNA were assessed by NanoDrop 2000 (Thermo Scientific) and by gel electrophoresis, respectively. The RNA was treated with TURBO DNase (Ambion®) to remove possible DNA contamination in RNA samples. The absence of genomic DNA was confirmed by gel electrophoresis and control real-time quantitative reverse-transcription PCR (qRT-PCR) reactions lacking reverse transcriptase enzyme. First strand cDNA synthesis was performed on 5 μg total RNA, using RevertAid H Minus M-MuLV reverse transcriptase (Fermentas, 50 U), Ribonuclease Inhibitor (Fermentas, 40 U), oligo (dT)18 primers (1 μg) in 20 μL. First strand cDNA samples were diluted in water to a concentration of 40 ng/μL and stored at −70 °C until use.

Real-time qRT-PCR {#s0002-0004}
-----------------

The transcript accumulation of each gene was detected by qRT-PCR using


wheat cultivars. Student\'s *t-*test was used to test for statistical significance (*p* \< 0.05).

Expression of *CBF* genes in wheat cultivars with different frost tolerance capacity {#s0003-0002}
------------------------------------------------------------------------------------

High-density mapping strategies, microarray analysis and quantitative RT-PCR have been extensively used to identify possible candidate genes for frost tolerance in both hexaploid and diploid wheat.\[[@cit0016],[@cit0019],[@cit0030],[@cit0054]\] Among different signalling pathways, the *CBF* regulon plays a pivotal role in cold acclimation of wheat and other cereal crops. The fine mapping of the *Fr-2* locus on chromosome group 5 in wheat revealed a complex structure including multiple *CBF* genes.\[[@cit0016],[@cit0019],[@cit0030],[@cit0037]\] According to Badawi et al.,\[[@cit0028]\] the cluster of *CBF* genes at *Fr-2* loci in hexaploid wheat includes *CBF*-2, -3, -4, -6, -9, -10, -12, -14, -15, -19, -20, -21 and -22. Knox et al. \[[@cit0041]\] described that *T.as Iraq and Syria.”

The facts suggest otherwise.

According to statistics analyzed by the Sydsvenskan newspaper, Malmo has a “murder index” of 3.4 when homicides for one hundred thousand inhabitants are taken into account, a “a very high figure” according to the report.

This compares to bigger but less dangerous cities in western Europe like Paris (1.8), London (1.3), Copenhagen (1.1) and Berlin (1.0).

Having recorded 11 murders in 2016, Malmo is easily the most dangerous city in the entire Nordic region.

.


not? while in  com.testing.classa.ClsA  had extends MyInterface ?
Question 2.
At (**): ERROR,
java.lang.IllegalArgumentException: argument 1 should have type com.example.my_interface.point, got com.example.my_interface.point

I think in main class had interface myinterface.jar, and on classA.apk had myinterface.jar too, and them can not talk together.
What's solution for this problem?
p/s: I searched on google, has someone suggest remove common lib from .apk (here myinterface.jar),
but, if removing it that will be can not build because errors.
Help me, thanks.

A:

You cannot cast as you tried, because you have two interfaces defined. they are called the same, but in different apks. The same applies for Point, thats why you get that second error.
Since you are already using reflection, you could go for full reflection and don't share a jar between the packages at all.
Another solution wouldI
think of it as a "transitive mapping": x to y and y to z gives x to z.
The data frame that I would like is...
x2z = data.frame( x = c("A","A","A","B","B","B","C","D","D","E","E","F","F","F"),
                  z = c(1,2,3,1,2,3,3,6,7,6,7,6,7,8) )

Notes: My data frames are usually ~50,000 rows, so efficient code is very important. When I've solved this problem with loops, it took several minutes to run.
My only requirement is that the code be in R.

A:

You want to merge:
merge(x2y, y2z)[c('x','z')]
##    x z
## 1  A 1
## 2  A 2
## 3  B 1
## 4  B 2
## 5  A 3
## 6  B 3
## 7  C 3
## 8  D 6
## 9


Hexasubstituted Benzenes with Ultrastrong Dipole Moments.
Hexasubstituted benzenes have been synthesized with the highest known dipole moments, as determined by dielectric spectroscopy and DFT methods. Based on the preparation of 4,5-diamino-3,6-dibromophthalonitrile, combined with a novel method to synthesize dihydrobenzimidazoles, these benzene derivatives have dipole moments in excess of 10 debye. Such dipole moments are desirable in ferroelectrics, nonlinear optics, and in organic photovoltaics. Structure determination was achieved through single-crystal X-ray crystallography, and the optical properties were determined by UV/Vis absorption and fluorescence spectroscopy.at the centre of? They did not campaign for Brexit, they did not put Trump in the White House, and they are not pushing back far-right gains in Europe. They are losing, and so the perceived architects of their disenfranchisement – the Nigel Farages and Steve Bannons and all the other dissimulating career nativists – will be entertained for as long as they are relevant. Even though in reality they are part-actors in the grand scheme of things, cast in a central role because that way they, and the story, sell better.

That is the real echo chamber: the one that leaves those at the sharp end of these debates out in the cold, even as they are accused of demanding a sanitised “dinner party” politics. Bannon is on


j?
9
Let q = 581 + -569. Calculate the highest common factor of q and 8.
4
Suppose 2*b - 32 = 58. Suppose 0 = 7*m - 2*m - b. Calculate the highest common factor of m and 54.
9
Let r be (-4 - 172/20)/(2/(-30)). Suppose -10*u + r = -21. Calculate the highest common factor of 147 and u.
21
Suppose 3*u - 370 = -2*l - 3*l, 370 = 5*l - 4*u. What is the greatest common divisor of 4 and l?
2
Let x = 21 + 47. What is the highest common divisor of 4 and x?
4
Suppose 0 = -5*p - 119*u + 123*u + 967, 3*p - 3*u - 579 = 0. Suppose 27 = g - 12. Calculate the highest common factor of p and g.
39
Let o be 288/16-90. Calculate the highest common divisor of b and y.
9
Suppose -2*r - 3*s + 24 = r, -5*s = 0. Let m be (0 - 1) + r/2. What is the greatest common factor of 6 and m?
3
Let t = -2061 - -2121. What is the highest common divisor of t and 24?
12
Let k(r) = -2*r**2 + 79*r - 40. Let g be k(35). Calculate the greatest common factor of 33 and g.
11
Let m = -161 - -230. Suppose 9*g - m = 102. Calculate the highest common factor of g and 38.
19
Suppose -3*o = 2*m - 67, 2*m = -5*o - 2*m + 113. What is the greatest common divisor of 3 and o?
3
Let f(r) = -r**2 + 5*r + 5. Let v be f(5). Suppose 0


in $L$, for each $n$.
$L$ is also in $NP$: the integer $n$ written in binary has length about $\log n$, so the decompression of this circuit has length no more than $O(n)$. Hence the satisfying assignment has length at most $O(n)$.
But by the same observations, if $L \in P$, then $NEXP=EXP$, because it means that you
have an $O(n^c)$ time algorithm for deciding every instance of Succinct 3SAT of length $\log n$.
Your second question is wide open (and open-ended).

A:

Here's a simplification of Ryan's answer. Suppose that $\Lambda \in NE \setminus E$. Define the language $L = \{x : |x| \in \Lambda\}$. The assumption $\Lambda \in NE \setminus E$ translates to $L \in NP \setminus P$. Also, trivially $L \in AC^0/poly$.

A:

To the question of Kaveh "Can non-uniformity help us      complaint.

       {¶ 19} R.C. 2152.021(F) contains a mix of mandatory and discretionary
language, but it is plain and unambiguous. And when statutory language is
unambiguous, we need not resort to rules of statutory interpretation—we simply
apply the language. Sears v. Weimer, 143 Ohio St. 312, 55 N.E.2d 413 (1944),
paragraph five of the syllabus.
       {¶ 20} R.C. 2152.021(F)(1)(a) and (F)(3) require the juvenile court to
appoint a guardian ad litem to assist a juvenile who has been charged with certain
solicitation or prostitution offenses—namely, violations of R.C. 2907.24
(solicitation), 2907.241 (loitering to engage in solicitation), and 2907.25
(prostitution). R.C. 2152.021(F)(1)(b) and (F)(3) require the same when the court
has reason to believe that the juvenile is a human-trafficking victim


N.E.2d 47 (1997). “Third, the error must have affected
‘substantial rights.’ We have interpreted this * * * to mean that the trial court’s
error must have affected the outcome” of the proceedings. Id.; see also Morgan at
¶ 50-51.
       {¶ 29} Martin argues that under R.C. 2152.021(F)(1)(b), the juvenile court
had “reason to believe” that she was a human-trafficking victim and that her
offenses were “related to” her victimization. Accordingly, Martin contends that the
court was required to appoint a guardian ad litem and exercise discretion regarding
whether to stay the complaint and impose diversion.
       {¶ 30} The state concedes that the juvenile court had reason to believe that
Martin was a human-trafficking victim, though it disputes that Kerney compelled
Martin to commit the   January Term, 2018

                                 CONCLUSION
       {¶ 36} The General Assembly enacted Ohio’s safe-harbor law because
human-trafficking victimization causes juvenile delinquency.             See 2012
Am.Sub.H.B. No. 262, Section 4. The law gives certain victims the chance to
rebuild their lives and avoid the justice system. Defense counsel, prosecutors, and
the courts must become familiar with this law and follow it when it applies.
       {¶ 37} R.C. 2152.021(F)(1)(b) and (F)(3) require a juvenile court to appoint
a guardian


     or of any other section for victimizing the child, and the act charged
       is related to the child’s victimization.
               ***
                (3) If either division (F)(1)(a) or (b) of this section applies,
       the court shall promptly appoint a guardian ad litem for the child.
       The court shall not appoint the child’s attorney as guardian ad litem.
       If the court decides to hold the complaint in abeyance, the guardian
   slavish relationship with him.
        {¶ 54} “Related to” is not defined in the statute. Black’s Law Dictionary
defines “related” to mean “[c]onnected in some way; having relationship to or with
something else.”      Black’s Law Dictionary 1479 (10th Ed.2014).          In Tyco
Healthcare Group, L.P. v. Ethicon Endo-Surgery, Inc., the Court of Appeals for the
Federal Circuit defined “related to” as follows: “In general, ‘related to’ means one
thing has some relationship or connection to another thing.” 587 F.3d 1375, 1378
(Fed.Cir.2009), citing Random House Webster’s Unabridged Dictionary 1626
(1998) (defining “related” to mean “associated, connected” and “allied by nature,
origin, kinship, marriage, etc.”).
        {¶ 55} The evidence established that


       randomVal = random.uniform(lowerBound, upperBound)
        yield randomVal
    else:
        for steppedVal in np.arange(lowerBound, upperBound, stepSize):
            yield steppedVal

for vectors in itertools.product(gen(True,3,6), gen(False,10,30,5)):
    print(vectors)

I get this, which is not what I want:
(4.4163620543645585, 10)
(4.4163620543645585, 15)
(4.4163620543645585, 20)
(4.4163620543645585, 25)

How could I modify this code so that each random number in this data set is unique without having to alter the data set after the fact as that adds huge compute overhead. (The actual data set contains a dozen or so variables with 10-20 steps each).
Edit, for clarification here is the desired output:
(4.1802347587349857, 10)
(3.7128578913746897, 15)
(5.8912734809721957, 20)
(4.4163620543645585, 25)

Edit 2,Laverdure must show: (1) the claimed variance

and (2) resultant prejudice to Laverdure’s rights. United States v. Adamson, 291

F.3d 606, 614-15 (9th Cir. 2002). Because Laverdure has not shown that her rights

were prejudiced, we do not consider whether a variance existed.

      Laverdure had ample opportunity to prepare a defense and the proof at trial

did not impermissibly go beyond the allegations in the indictment. See United

States v. Morse, 785 F.2d 771, 775 (9th Cir. 1986) (“[P]rejudice may result in three

ways: 1) inadequate opportunity to prepare a defense and exposure to unanticipated

evidence at trial; 2) deprivation of the right to be tried only on charges presented in


No longer a boys’ club, the project — penned by Albert Kim (Sleepy Hollow, Nikita) — will revolve around a diverse team of male and female American Special Forces operatives. Framed for a crime they didn’t commit, the group attempts to clear their names by uncovering the black-ops conspiracy that set them up. The mission-of-the-week format also finds the team using their singular military skills, high-tech expertise and conflicting individual approaches to help others in need.specific genetically engineered mouse model (GEMM), in which *PIK3CA* is overexpressed in head and neck epithelium. Our results showed that in this GEMM overexpression of *PIK3CA* alone resulted in head and neck epithelial hyperplasia but was not sufficient to initiate tumorigenesis. However, overexpression of *PIK3CA* significantly increased susceptibility to oral carcinogen-induced head and neck tumorigenesis. Strikingly, *PIK3CA* overexpression promoted HNSCC invasion and metastasis through epithelial-mesenchymal transition (EMT) and enrichment of putative head-and-neck cancer stem cells (CSCs). Further molecular studies showed that activation of PDK1 and enhanced TGFβ signaling play an important part in HNSCC progression. Our findings highlight the key role of PDK1 and TGFβ signaling in HNSCC invasion and metastasis, and suggest that targeting PDK1 and TGFβ signaling may be effective approaches to controlling HNSCC progression, particularly


body weight) between the control mice and the *PIK3CA-*GEMM*s*.

Overexpression of PIK3CA in murine head and neck epithelia promotes tumor invasion and metastasis {#S4}
-------------------------------------------------------------------------------------------------

It was immediately clear that tumors from *PIK3CA-*GEMMs and those from control mice differed in gross appearance: while most control tumors were papillomatous, tumors from the *PIK3CA-*GEMMs were flat ([Figure 2c](#F2){ref-type="fig"}). Histologically, the majority of the control tumors had an out-growth pattern with intact basement membranes (left panels of [Figure 2d](#F2){ref-type="fig"} and [Supplementary Figure S3](#SD2){ref-type="supplementary-material"}), while tumors from the *PIK3CA*-GEMMs predominantly had a down-growth pattern with broken basement membranes and invasion into muscle (right panels of [Figure 2d](#F2){ref-type="fig"} and [Supplementary Figure S3](#SD2){ref-type="supplementary-material"}). While over 60% of the control tumors were well-differentiated or carcinoma in situ, over 50% of the *PIK3CA-*overexpressing tumors were poorly-differentiated as confirmed by*PIK3CA-*GEMM tumors ([Figure 4b](#F4){ref-type="fig"}). Similarly, IHC staining showed an increase of total PDK1 protein in the *PIK3CA-*GEMM tumors ([Figure 4c](#F4){ref-type="fig"}). These findings were unexpected and suggested that PDK1 may mediate oncogenic signaling in *PIK3CA*-driven HNSCC progression. Lastly, we examined several molecules which are commonly altered in human HNSCCs. 4NQO exposure causes the formation of DNA adducts, resulting in mutations.^[@R19]^ We first examined two oncogenes that are commonly mutated in HNSCC, i.e. *Ras* and *PIK3CA*. We sequenced eight *PIK3CA*-GEMM tumors and eight control tumors for mutations at codons 12, 13 and 61 of the *K-ras* and *H-ras* genes, and exons 9 and 20 of the *PIK3CA* gene. The only mutation we found was a G to A point mutation in codon 12 of mouse *K-ras* gene, which changes glutamic


of cases with immunostaining ≥2+ in HNSCC tumors and metastases. Consistent with *PIK3CA* qRT-PCR results, we found increased p110α immunostaining both in poorly-differentiated HNSCCs and in metastases ([Figures 7b and c](#F7){ref-type="fig"}). Interestingly, PDK1 expression positively correlated with *PIK3CA* expression and advanced disease ([Figures 7b and c](#F7){ref-type="fig"}). However, AKT activation showed the opposite pattern, and demonstrated reduced expression in poorly-differentiated tumors and metastases compared to early stage lesions. These data from human tissue sample support our mouse model data that *PIK3CA*-driven HNSCC progression is predominantly mediated through PDK1, but not through AKT.

Discussion {#S10}
==========

Previous mouse models were generated by knocking in *PIK3CA* mutant *H1047* into different tissue contexts.^[@R25]--[@R29]^ However, somatic mutations of *PIK3CA* are infrequent (\~10%) compared to *PIK3CA* gene amplification (\~40%) in HNSCC patients.^[@R4],[@R5]^ Thus, our *PIK3CA*-GEMM, in whichago. I yawned and moved to click off the light.

“Wait!” I heard, the same boy making his presence known, “Could we – talk?”

I raised my eyebrow.

“Sure,” I said, “Let’s sit over by the fire pit so not to wake the others.”

We walked about ten feet over to the small ring of stones where we had recently cooked smores. My co-counselor was watching the last of the smoke rise from the ashes.

“We got it from here, James,” I said. He nodded and headed over to his nearby hammock.

We sat by the fire for a moment before I ventured, “What’s up?”

I couldn’t see the camper’s face. The darkness had obscured his eyes from me. He said nothing, though it looked as though he was searching for words.

I heard water hitting


had been suddenly struck with a sense of loss. The room was filled with people, with memories, once – not even a week ago. Now, it was gone, disappeared into the past.

I had come to call the place home. But, as the walls and the room itself became increasingly bare, the very life that resided within the room breathed its last. I was looking at the corpse of a year’s worth of strangers who became my family, of mornings and nights filled with incredibly meaningful conversations, of “mountaintop experiences” and more than one visit to the valley of the shadow of death. And my friends were there through it all.

And now, now it was all over.

A lump formed in my throat as I stepped outside. A friend wasto optimal electromagnetic enhancements in SERS \[[@B2-nanomaterials-09-00677]\]. Such control on plasmonic properties is required for effective application of SERS in analytics \[[@B14-nanomaterials-09-00677],[@B19-nanomaterials-09-00677]\]. We have employed these films in TDM, focusing on two AEDs (Carbamazepine---CBZ, Perampanel---PER). In the case of CBZ, we prove that a SERS substrate can be re-utilized at least five times by washing it with methanol. We also show the good linear dependence of the SERS signal vs. CBZ concentration in the range 2.5 × 10^−5^ M to 2.1 × 10^−4^ M. In the case of PER, we exploit the protonation mechanism of the drug by HCl, as suggested by observed changes of the C=O stretching transition between Raman and SERS, and UV-Vis data taken on PER in acidic conditions. This paves the way to the


a solid Au target in high-pressure inert gas and mutually assembled on an inert (glass) support behave as SERS sensors with good performances \[[@B16-nanomaterials-09-00677]\].

In [Figure 4](#nanomaterials-09-00677-f004){ref-type="fig"}, we show the surface nanostructure of an Au film deposited on (100) Si (ablation in Ar at 100 Pa; $N_{LP}$ = 2 × 10^4^). As shown in [Figure 4](#nanomaterials-09-00677-f004){ref-type="fig"}, the SPR of films produced with this set of process parameters and deposited on glass matches the popular 785 nm laser excitation found in commercial Raman instruments, including portable ones. We used substrates of this kind, either deposited on glass, or on Si, throughout all investigations on CBZ. Part of the data we discuss on CBZ was presented in \[[@B6-nanomaterials-09-00677]\]. Here, we complete the data analysis including additional SERS markers, and we showCOSMO-RI-ADC(2) excitation energies and excited state gradients.
We present an implementation of analytic gradients for electronically excited states for the algebraic-diagrammatic construction through second order, ADC(2), in combination with the conductor-like screening model (COSMO) as an implicit solvent model. The implementation uses a post-SCF reaction field scheme for the coupling between the environment and the quantum system which retains the computational efficiency of the gas-phase RI-ADC(2) calculations. Applying this approach, we computed solvatochromic shifts for UV absorption and fluorescence transitions of 4-(N,N-dimethylamino)benzonitrile using equilibrium geometries for the ground and the first excited states optimized in the presence of acetonitrile as solvent. Furthermore, we investigated the excited state energies and geometries of the 2-iodobenzimidazolium·triflate ion pair in aqueous solution as an example where solvent effects have a large influence on


It has previously been recognized that boats and other watercraft operate better with adjustable trim tabs. Trim tabs are typically mounted at the stern of the vessel and are controllably extended to affect the flow of water passing about the vessel. The attitude or orientation of the watercraft is thereby affected.
Most prior trim tab systems employ hydraulic rams which extend port and starboard trim flaps. The trim flaps are extended downwardly to lower the bow of the boat. An example of such a system is shown in U.S. Pat. No. 3,695,204.
Hydraulic trim tab systems have suffered from certain limitations. Foremost is the relatively abrupt action of hydraulic trim tabs which oftentimes result in an uncomfortably abrupt change in boat attitude. Hydraulic systems also employ oil which can beThe Supreme Court has no shortage of potentially precedent-shattering cases on its docket this term. But the one the justices are hearing tomorrow, King v. Burwell, could be the most consequential.

King focuses on the issue of whether low-income people who get insurance under the Affordable Care Act’s federal exchanges are entitled to tax subsidies. Much has been said (and written) about what could happen if the justices rule “no”: Millions of people in as many as 37 states could lose their health coverage. The political earthquake could be cataclysmic.

Yet, few reports have highlighted the role of theFederalist Society, the conservative law group whose ideas are at the intellectual heart of the King v. Burwell challenge. That’s not surprising, given that the group’s members have played a mostly behind-the-scenes


precedent has further contributed to the narrowing of the federal commerce powers.

It’s true, Chief Justice Roberts found a way to salvage the ACA’s individual mandate based on the power of Congress to impose taxes. That made many conservatives very unhappy. But the Federalist Society didn’t just get half a loaf, it got 80 percent of the loaf.

Q. King v. Burwell is avery different type of case. How does the issue at the center of it reflect Federalist Society thinking?

A. Unlike the 2012 challenge to the ACA, King v. Burwell is not a constitutional case. It’s a statutory case. At issue is whether people in states with federally facilitated health insurance exchanges are entitled to receive the tax benefits that make insurance affordable. The parties in this case areprobability to have a close approach with the planet, and does not approach the other two planets.

Of course the singular event depends mainly on the entry velocity. The “entry velocity” is the velocity of the asteroid when it arrives for the first time at the maximum distance established for a close encounter from the planet.

On average the mean duration of close encounters with Mars is about half a day, and this is the highest value for the terrestrial planets. In summary: $0.27\pm0.05$ d for Venus, $0.36\pm0.09$ d for Earth and $0.55\pm0.05$ d for Mars.

The Hungaria-fugitives seem to have more close encounters, even if the scattering of encounters’ mean is relatively high, with the Earth respect to the other planets. In fact the average number of close encounters for


and 30 My, but this does not affect the behaviour of increasing the number of NEAs during this interval of time (see Fig.\[evonea\]). Then there is a time span of circa 20 My without impacts with planets (but only with the Sun), starting again in the last 30 My. Other objects that finish may have an impact with Jupiter too, but we did not take in account the study of close encounters with this planet in this work and usually we see a not significant value of asteroids that cross the Jupiter’s orbit. So the most important bodies in cleaning up the Hungarias-NEAs seems to be in order the Sun and Venus. It is important to notice that there is a certain probability (even if it is verythe first clone become a NEA. The second one is the average time for the clone to become NEAs. Right pannel: Eccentricity versus time.[]{data-label="aveseminea1997"}](5R.eps "fig:"){width="45.00000%"} ![Averaging of the elements with the standard deviation of the 50 clones of the asteroid (152648) 1997 UL$_{20}$. All points with a standard deviation major than 50% of the measure of the average has been rejected. Left pannel: Semi-major axis versus time for the averaging, at $\sim$ 58 My there is a large scattering. The first vertical line is the time when the first clone become a NEA. The second one is the average time for the clone to become NEAs. Right pannel: Eccentricity versus time.[]{data-label="aveseminea1997"}](6R.eps "fig:"){width="45.00000%"}

The *NormHNeas* initially decreases their semi-major axis more than 0.05 AU (as a whole) in the first


the measure of the average has been rejected. Left pannel: Semi-major axis versus time for the averaging. Right pannel: Eccentricity versus time.[]{data-label="aveseminea1997"}](7R.eps "fig:"){width="45.00000%"} ![Averaging of the elements with the standard deviation of the 50 clones of the asteroid (211279) 2002 RN$_{137}$ when they are NEAs. All points with a standard deviation major than 50% of the measure of the average has been rejected. Left pannel: Semi-major axis versus time for the averaging. Right pannel: Eccentricity versus time.[]{data-label="aveseminea1997"}](8R.eps "fig:"){width="45.00000%"}

Conclusions {#spec}
===========

As main result of our integration we found that the preponderance of the Hungaria escapers become NEAs, so also Mars-crossers. 78% has CE with Mars, 29% with the Earth and 24% with Venus. Also 37% finish their lives as Sun-grazers, if they do not collide with a planet before that.

Thereis a small number of them (with a very low probability: $<1\%$) that leave the inner main belt crossing the region of the Centaurs and Trans-Neptunian Objects (TNOs).

Some Hungarias pass a long time in the outer solar system, via comet-like orbits, because we observed very high eccentricities when they are NEAs and even at higher inclinations than the initial conditions.

The average time for a first close encounter with Venus is $\sim 63$ My after the initial conditions, but it is somewhat surprising that this time is not much smaller for the Earth $\sim 62$ My; the first CE with Mars the average time is lower $\sim 14$ My. They become NEAs on average after $\sim$ 47 My.

In the case of Hungaria-derived Apollos or Amors, the Earth is flattening


D.,[Radiometric Diameters for 84 asteroids from observations in 1974-1976.]{}, [The Astrophysical Journal]{} [**214**]{}, 667–677(1977)

, P., and 31 co-authors, [Spin rate distribution of small asteroids.]{}, [Icarus]{} [**197**]{}, 497–504 (2008)

, A., [Marzari]{}, F., [Scheeres]{}, D. J, [Computing the effects of YORP on the spin rate distribution of the NEO population.]{}, [Icarus]{} [**202**]{}, [95–103]{} (2009)

, E.M., [Williams]{}, J.G., [Helin]{}, E.F., [Wolfe]{}, R.F., [Earth-crossing asteroids: orbital classes collisions rates with Earth, and origin]{}, [Asteroids]{} [253-282]{} (1979)

, B. D., [Harris]{}, A. W., [Lightcurve studies of small asteroids.]{}, [BAAS]{} [**39**]{}, [432]{} (2007)

, B. D., [Harris]{}, A. W., [Vokrouhlický]{}, D., [Nesvorný]{}, D., [Bottke]{}, W. F., [Analysis of the Hungaria asteroid population.]{}, [Icarus]{} [**204**]{}, [172-182]{} (2009)

, V., [Cellino]{}, A., [Dell’Oro]{}, A., and [Paolicchi]{}, P., [Physical and dynamical properties of asteroid families]{}, [In: W.F. Bottke, A. Cellino, P. Paolicchi, R.P. Binzel, Editors]{}, Inpeople in need to those seats, and keep others who don't have problems off the benches.

Not all or even half of those people get an awesome ride in an art car with a great veiw. Or can ride a bike due to their condition.
Let us come together and figure out a solution! Let us unite and make this a reality to make a zen/peaceful atmosphere!

DPW can not be taking care of evey little problem we have such as sitting down to be polite! We must all come to gething to work towards a solution!

Great opinion Simon.
All I'm saying is if someone wants to make some benches for the disabled, that would be great!
I'm not saying be nice to the rest of the people who wont sit down for


changes within a short time as it is repeatedly changed many times. Consequently, the object is likely to vibrate in a higher-order mode. That is, the dead beat control is much influenced by disturbance and higher-order mode. It is therefore an impractical method of controlling the positioning of the head of an HDD.
A digital position control system has been proposed which is a combination of dead beat control and model following control. As shown in FIG. 6, this control system comprises a model following control section 23 and a dead beat control section 24. The dead beat control section 24 generates a reference control value. A model 26 is a mathematical formula, or the equation of motion, which represents the dynamic characteristics of a plant 25 (i.e., object).a are the corresponding predictions for $F(\twf)$ (see text). All data refer to species $a$ of the KALJ mixture. Analogous results for species $b$ are shown in Fig.S1. ](Fig1.eps)

In order to prove that the CTRW approach provides a quantitative description of the dynamics of the KA mixture, we have performed a careful analysis of the single particle cage–jump intermittent motion, for temperatures slightly above the mode–coupling one[@KA1; @KA2; @KA3], $T_{\rm mct} \simeq 0.435$. Fig. 1a–c illustrate the distribution of the persistence time $F(\twf)$ and of the jump length $P(\Delta r)$, that fix the temporal and spatial features of the system in the CTRW approach, as well as the distribution of the time particles wait in their cages before making a jump, $P(\tw)$. No correlations between the persistence time


and the jump length have been found, in agreement with the CTRW scenario. Panel d illustrates the decay of the persistence. At short times all jumps contribute to the decay of the persistence; we therefore observe $p(t)=1-t/\<\tw\>$, as $\<\tw\>^{-1}$ is the rate at which particles jump, and $F(\twf) = -dp(t)/dt = \<\tw\>^{-1}$. At long times ($t \simeq t_p$) the persistence is found to decay with a stretched exponential, $p(t) \propto \exp\left(-(t/\tau)^\beta\right)$. This implies $F(\twf) = -dp(t)/dt \propto \tau^{-\beta} t^{\beta-1} \exp \left(-(t/\tau)^\beta
\right)$ as verified in Fig.\[fig:p\_njumps\]a.

![\[fig:times\] Cage–jump time and length scales. Temperature dependence of the average time particles persist in a cage before making the first jump, $\<\twf\>$, and of the average cage residence time, $\<\tw\>$. $\<\tw\>$ is well described by an Arrhenius $\<\tw\> \propto \exp\left(A/T\right)$ (full line).Value For Money

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brand is healthy and necessary.

There are many elements that go into building a brand — name, symbols, packaging, product and reputation. Research published in the Journal of Marketing Communications (1998) by Leslie de Chernatony and Francesca Dall’Olmo Riley reports that there is little agreement on the definition of a brand. Part of the reason is that branding is a process that collectively conveys all the internal and external perceptions of an organization. It is the personification of the work that is undertaken. As such, any organization or individual is a brand. It speaks of your personality, outlook and vision of the world.

Since there are so many stakeholders in an organization, getting a personality profile requires the application of a number of tools that have to work in tandem.we see it every day in action. For example, Coca-Cola, in spite of its critics, remains a consistent household brand name. Its mission is to bring pleasure to the taste buds It knows what it does. The same thing goes for PETA and the American Red Cross in the nonprofit world. No matter what your feelings are about them, everyone knows who PETA and the Red Cross are. That's because they know who they are, what their missions are, and they convey that to donors. Knowing what you are is the best and only defense against critics. People gravitate toward confidence.

For your organization’s brand to survive in a fast-changing environment, know what you do and why you do it. What is your mission? What is your organization’s name,


Fitsame Teferra an accomplished Ethiopian publisher of children’s books is making reading stories a pleasant adventure for kids of African descent born here in Germany.

Her recent endeavour has seen story lines picked from a contemporary Swahili society, and translated into German for kids of Kenyan descent. She says authentic children stories are quickly being replaced by the internet and social media, and therefore her books help to fill the gap.

Before coming to Germany, Fitsame had 30 books under her belt, all published in Amharic. She worked with several children projects in Ethiopia, including Save the Children, where local stories about children came to life.

She narrates that born out of a passion for books, she noticed that although literal publications were diversifying in character and production, there were fewbringing on board stories from other writers.

Now working with the Habte publishers, Fitsame draws experiences from German writers who have an authentic background about life and growing up in Germany. She has also incorporated other genres of books in her projects, and now extends to cook books and recipes in German- Swahili.

In her children’s book, a 7-year-old Ayani of Ethiopian and German parenthood is depicted a little girl, who tells the stories from African contexts to German settings. Ayani with permission from her parents allowed her name and images to be used illustratively in the books.

The parents are consulted in all the work with the children. Fitsame says that Parents have welcomed the new book idea, since it was difficult to get relevant material with connection to African


pps. The absolute median difference of depleted iron stores compared with the difference when these factors were not controlled was −0.2 pps (range: −0.2 to 0 pps) for the IRC-AGP approach in WRA.

DISCUSSION
==========

We conducted a multicountry analysis with various approaches to correct sTfR concentrations in the presence of malaria or inflammation (or both) because of the challenges in accurately estimating iron-deficient erythropoiesis with the use of sTfR. Adjustment for inflammation or malaria, regardless of the approach explored, resulted in a reduced prevalence of elevated sTfR concentrations in PSC and WRA, although the reduction was more marked in PSC. These findings were strengthened by the large sample size of the data set compared with in previous studies with similar findings ([@b9]--[@b11]). sTfR has been considered by many researchers as# -*- coding: utf-8 -*-
# Copyright (C) 2014-2017 Andrey Antukh <niwi@niwi.nz>
# Copyright (C) 2014-2017 Jesús Espino <jespinog@gmail.com>
# Copyright (C) 2014-2017 David Barragán <bameda@dbarragan.com>
# Copyright (C) 2014-2017 Alejandro Alonso <alejandro.alonso@kaleidos.net>
# Copyright (C) 2014-2017 Anler Hernández <hello@anler.me>
# This program is free software: you can redistribute it and/or modify
# it under the terms of the GNU Affero General Public License as
# published by the Free Software Foundation, either version 3 of the
# License, or (at your option) any later version.
#
# This program is distributed in the hope that it will be useful,
# but WITHOUT ANY WARRANTY; without even the implied warranty of
# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
# GNU Affero General Public License for more details.
#
# You should have received a copy of the GNU Affero General


into another Excel file.

The biggest hurdle with this project was the fact that Sort Your Music doesn’t give you anything associated with the date you listened to a specific song, and mapping the two data sets together based on date proved difficult. In lieu of a date for the Spotify based data, I kept the order of the scrobbles in tact in the Spotify playlists (for example, #1 would be the first scrobble of the year, #10,000 would be the 10,000th, etc), so I could use that # field as a proxy for the date, as shown in many of the visualizations below.

Quick Look

I broke the data that came out of the Sort Your Music tool into monthly chunks that I tried lining up with the Scrobbles datasignificant effect on the type of music that I listened to. Unfortunately, no matter how I sliced the data, there was no consistent or reasonable conclusion to be found between the two sets. This most likely is because of the fact that 1) there was so much data (on average, about 35 scrobbles/day) that any coincidental correlation was erased, and 2) my listening trends, as stated above, were remarkably consistent over time, regardless of the metric used.

Conclusions:

Contrary to the belief that I listen to a wide variety of music, my taste is extremely consistent in terms of BPM, the ratio of song release dates, and individual song length.


Filed May 12, 2016.

      Charles Zagara, for petitioners.

      Karen Lynne Baker, for respondent.

                           MEMORANDUM OPINION

      LAUBER, Judge: In this collection due process (CDP) case, petitioners

seek review, pursuant to sections 6320(c) and 6330(d)(1),1 of the determinations

by the Internal Revenue Service (IRS or respondent) to uphold notices of Federal

      1
       All statutory references are to the Internal Revenue Code in effect at all
relevant times, and all Rule references are to the Tax Court Rules of Practice and
Procedure. Weeveryone likes to beat up on the usual suspects like Facebook when it comes to the inexorable spread of fake news, but the problem is actually more pervasive than you may realize. Indeed, Buzzfeed walks through how even Apple’s Safari browser inadvertently enables the surfacing and spread of conspiracy theories and fake news.

It does so via Siri’s suggestions of content it surfaces whenever you swipe to the right on your iPhone and type something into the search bar.

As of Monday, Buzzfeed reports, “if you typed ‘Pizzagate’ into Apple’s Safari, the browser’s ‘Siri Suggested Website’ prominently offered users a link to a YouTube video with the title ‘PIZZAGATE, BIGGEST SCANDAL EVER!!!’ by conspiracy theorist David Seaman (the video doesn’t play, since Seaman’s channel was taken down for violating YouTube’s


the present custody dispute demonstrates that my concern was real and not fanciful.
In both White and Burnside, the majority could at least point to something in the particular mother's emotional makeup, or in her proposed living arrangements for the child, to justify the conclusion that the child's welfare would be better served by continuing custody in the father.  But here, absent even a hint of the unsuitability of the mother or her home, she is denied custody for the sole reason, as expressed in the majority opinion, that the children involved in this case "have now resided with their father for approximately three years" and "are doing well in their present environment." Not on such slim grounds would I deny the mother custody or deprive the childrenPhilidas

Philidas Ltd. (previously named Infast Philidas) is a company based in Pontefract, West Yorkshire, England that manufactures nuts and components for automotive and industrial applications.

History
The company was established in 1942, and is a branch of the Haden MacLellan engineering group. Prior to this the company was a part of B Elliott, which sold Philidas to Haden MacLellan in 2000. Philidas manufactures automobile fasteners in both small and large-scale batches. The company's products are distributed on a global basis. In 2005, it was reported that the company manufactures 110 million fasteners annually. Philidas had a factory on Monkhill Lane, Pontefract. But this closed in January 2014. Some of Philidas' clients include BMW, Jaguar, Ford and Bosch.

Philidas nut
A Philidas nut is a locknut with one or more slots cut laterally


<!-- Licensed under a BSD license. See license.html for license -->
<!DOCTYPE html>
<html>
  <head>
    <meta charset="utf-8">
    <meta name="viewport" content="width=device-width, initial-scale=1.0, user-scalable=yes">
    <title>Three.js - Shadows - Directional Light w/CameraHelper</title>
    <style>
    html, body {
        margin: 0;
        height: 100%;
    }
    #c {
        width: 100%;
        height: 100%;
        display: block;
    }
    </style>
  </head>
  <body>
    <canvas id="c"></canvas>
  </body>
<script type="module">
import * as THREE from './resources/threejs/r119/build/three.module.js';
import {OrbitControls} from'./resources/threejs/r119/examples/jsm/controls/OrbitControls.js';
import {GUI} from '../3rdparty/dat.gui.module.js';

function main() {
  const canvas = document.querySelector('#c');
  const renderer = new THREE.WebGLRenderer({canvas});
  renderer.shadowMap.enabled = true;

  const fov = 45;
  const aspect = 2;  // the canvas default
  const near = 0.1;
  const far = 100;
  const camera = new THREE.PerspectiveCamera(fov, aspect, near, far);
  camera.position.set(0, 10, 20);

  const controls = new OrbitControls(camera, canvas);
  controls.target.set(0, 5, 0);
  controls.update();

  const scene = new THREE.Scene();
  scene.background = new THREE.Color('black');

  {
    const planeSize = 40;

    const loader = new THREE.TextureLoader();
    const texture = loader.load('resources/images/checker.png');
    texture.wrapS = THREE.RepeatWrapping;
    texture.wrapT = THREE.RepeatWrapping;
    texture.magFilter = THREE.NearestFilter;


Cytokeratins and mucins as molecular markers of cell differentiation and neoplastic transformation in the exocrine pancreas.
Acinar and ductal cells of the normal pancreas express cytokeratin (CK) patterns which indicate a heterogeneity of ductal epithelia. On account of the CK of pancreatic adenocarcinoma, it would seem to be probable that tumor epithelia possess a considerable potential for squamous epithelium metaplasia. Comparative studies of CK expression by ductal carcinoma of the pancreas and carcinoma of bile ducts, stomach and large intestine as well in cases of chronic pancreatitis have demonstrated the usefulness of CK for differential diagnosis of these conditions. From the number of apomucins, mainly MUC1 is produced in the normal pancreas. This capacity is maintained in pancreas carcinoma and cell lines derived from it.from Reed gave the Hoos a first down, but the drive fizzled out at the South Carolina 49-yard line. AFter a punt from Coleman, the Gamecocks took over at their own 16-yard line.

Crosby fumbled the ball on the first play from scrimmage for USC in the second half, but he recovered his own mistake. Bentley found Smith for a 12-yard pickup to get the Gamecocks to a manageable 3rd-and-3. Virginia wouldn’t relent as Mack came off the edge untouched to wrap up Bentley for the Hoos’ second sack of the game. South Carolina would punt to Virginia, and Billy Kemp returned the ball 11 yards to set up the Hoos at the SC 39-yard line.

Perkins scampered eight yards for a first down after Ellis picked up three yards,


Vice” will mark the second project based off a previously published work and it remains to be seen if Anderson will stick to the pages of Pynchon’s work or, like he did with “Oil!” by Upton Sinclair (which was turned into “There Will Be Blood”), spin it into something uniquely his own.

Logged

“Don't think about making art, just get it done. Let everyone else decide if it's good or bad, whether they love it or hate it. While they are deciding, make even more art.” - Andy Warhol

It seems like a definite step backwards after TWBB. It points to him going back to his Scorcese/Altman phase, which I was kind of happy he had behind him.

I dunno about that. PTA always seems to be stretching himself with each project:Inherent Vice as a jumping off point for a sci-fi thriller set on a space station.

I don't know if it's a step down for PTA. It isn't a Thomas Pynchon epic. It's a pretty light book for him so in the pantheon of recent filmmakers trying to take on huge novels, PTA would be downsizing compared to the Wachowski Brothers taking on Cloud Atlas and Ang Lee adapting Life of Pi. Those are big books. However, it will be how he adapts this book. He will have numerous ways to go about it and at least I believe would be different than anything he has ever done before. For a filmmaker who is still relatively young, that is important.

Still, I will wait for more confirmation before believing this


Albuera, Ciudad Rodrigo, Battle of Badajoz, Salamanca, Vittoria, San Sebastián, Nivelle, Nive, and Toulouse.  His Peninsular Gold Medal had six clasps – only the Duke of Wellington, with nine clasps, Sir Dennis Pack and Lord Beresford, with seven each, had more clasps to their medal.

Later career
He died, a major general and Knight Grand Cross of the Order of the Bath, in 1840. A memorial was erected at Woolwich in 1847. Dickson was one of the earliest fellows of the Royal Geographical Society.

His diaries kept in the Peninsula were the main source of information used in Duncan's History of the Royal Artillery.

Notes

References

Category:1777 births
Category:1840 deaths
Category:Graduates of the Royal Military Academy, Woolwich
Category:British Army generals
Category:Knights Commander of the Royal Guelphic Order
Category:Knights Grand Cross of the Order of the Bath
Category:Fellows of theplugin.
Only way this works is if I debug step by step in the firebug, then the value is passed, else it fails.

A:

Basically add event.preventDefault();after ajax call
Something like this,
$('.single_add_to_cart_button').click(function(event) {
  $.ajax({
    type: "POST",
    url: script_e.ajaxurl, //url loaded from the plugin
    data: {id:test},
    cache: false,
    success:  function(data){
      alert(data);
    }
  });
  event.preventDefault();
});


Intel ISEF

Two Vietnamese high school students won 3rd place at the 2018 Intel International Science and Engineering Fair this weekend for their research on an antibiotic resistant infection. The ISEF was sponsored by Intel this year, bringing together students from 81 countries with 1,383 projects in 22 different research categories. Judging took place in Pittsburgh, PennsylvaniaRead More…Chile's currency dropped to a record low on Tuesday as hundreds of thousands took to the streets with anti-government demonstrations showing no signs of abating.

Citizens marched peacefully in Santiago, gathering in the capital's Plaza Italia district, brandishing both national and Mapuche indigenous group flags. Nearby, protesters confronted police, who used water cannons and tear gas to disperse them.

Read more: Opinion: Latin America needs solidarity

Demonstrations were also in full flow in the coastal city of Valparaiso as citizens forced government offices and local transport to shut down.

Protesters clash with security forces during a protest against Chile's government in Valparaiso, where a number of government buildings were forced to close down

Chile is one of the wealthier countries in Latin America, but it is also one that has a large disparity


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By registering with us, you are confirming that you will not use the Service to accept payments in connection with the following businesses, business activities or business practices.

Virtual currency that can be monetized, resold, or converted to physical or digital products and services or otherwise exit the virtual world (e.g., Bitcoin); sale of stored value orof material under time-dependent heat flux. The ignition delay time is expressed as a function of the total energy delivered to the surface.

Almost all of these criteria adopt the surface absorption hypothesis, coupling the external incident heat flux in surface boundary conditions. This assumption is credible and reasonable for infrared opaque materials. However, for a translucent solid, like some polymers, in-depth absorption exerts its influence on thermal degradation and subsequently affects the ignition mechanism. Recently, this subject has been paid great attention in some pyrolysis models (e.g., \[[@B8-materials-09-00820],[@B9-materials-09-00820],[@B22-materials-09-00820]\]). In these models, incident heat flux is absorbed inside the material gradually and no energy is absorbed on the surface. Both surface and in-depth absorption are idealized cases, and the failure of the classical ignition theory is confirmed by experiential


validity of the model could be promoted by considering the heat flux spectrum for a fixed λ.

Measured mass loss rate in tests can also be employed to optimize λ. Since the optimization process has been conducted in ref. \[[@B27-materials-09-00820]\] for coated black PMMA, only the comparison between the numerical model and experimental data of uncoated clear PMMA available in ref. \[[@B29-materials-09-00820]\] is exhibited in [Figure 9](#materials-09-00820-f009){ref-type="fig"}. The optimized λ = 0.17 is obtained according to the residual analysis for κ = 2250 m^−1^. The agreement between experimental, numerical and FDS \[[@B9-materials-09-00820]\] is fairly good. Combining with the corresponding optimized λ = 0.70 for coated clear PMMA discussed above, it can be concluded that the coated layer increases the surface absorptivity by 0.53 for clear PMMA. Obviously, this valueand how I
might build a service that buys numbers for people.

------
Symbiote
I've inherited (then reinstalled) a monitoring system using SMS Tools. The
modem has a long USB cable, and an external antenna. I positioned the antenna
on top of the rack.

It's in the middle of the ground/machine floor of a large building, so there's
a lot of thick concrete walls around, but it gets a good signal and reliably
sends SMS alerts to me.

------
babayega2
The same project using an SMS modem , kannel and Django
[https://hackernoon.com/build-an-sms-center-with-python-
kanne...](https://hackernoon.com/build-an-sms-center-with-python-kannel-and-a-
gsm-modem-9c0d29560d82)

Edit: and a repository of modems that can send SMS on Linux is here :P
[https://wammu.eu/phones/](https://wammu.eu/phones/)

------
mateuszf
For personal usage: if you have an Android phone and are not bothered by web
ui, you can use [https://messages.android.com/](https://messages.android.com/)

~~~
gh02t
Side note, is it just me, or is the Android Messages app really laggy?
Especially on the phone, there


the algorithmic group fairness literature has focused on the simplest case where there are only two groups. In this paper, we consider the more nuanced case of group fairness with respect to multiple groups.

The simplest setting is the [*independent*]{} case, with only one sensitive attribute which can take multiple values, e.g., race only. The presence of multiple sensitive attributes (e.g., race [*and*]{} gender simultaneously) leads to non-equivalent definitions of group fairness. On the one hand, fairness can be considered independently per sensitive attribute, leading to overlapping subgroups. For example, consider a model restricted to demographic parity between subgroups defined by ethnicity. Simultaneously, the model can be constrained to fulfill demographic parity between subgroups defined by gender. We term fairness in this situation *independent group fairness*. On the otherg) = \sum_{\ell} {\bC}^g_{k,\ell} $ be the probability of label $k$ given group $g$.

[**The sample confusion matrix**]{} is defined as $\mat{\sConf}[\vect{h}] = \frac{1}{n} \sum_{i=1}^n \mat{\sConf}^{(i)}[\vect{h}]$, where $\mat{\sConf}^{(i)}[\vect{h}] \in [0, 1 ]^{K\times K}$, and $\sConf_{k,\ell}^{(i)}[\vect{h}] = \indicator{y_i=k}h_\ell(\bx_i)$. Here, $\indicator{\cdot}$ is the indicator function, so $\sum_{k=1}^{K}\sum_{\ell =1}^{K}\sConf_{k,\ell}^{(i)}[\vect{h}]=1$. [*The empirical group-specific confusion matrices*]{} ${\widehat}{\mat C}^g$ are computed by conditioning on groups. In the empirical case, it is convenient to represent group memberships via indices alone, i.e., $\bx_i \in g$ as $i \in g$. We have $\mat{\sConf}^g[\vect{h}] = \frac{1}{|g|} \sum_{i\in g} \mat{\sConf}^{(i)}[\vect{h}]$.

[**Fairness constraints.**]{} Let ${\cG_{\text{fair}}}$ represent the (potentially overlapping) set of groups across which we wish to enforce fairness. The following states our formal assumptions on ${\cG_{\text{fair}}}$.

${\cG_{\text{fair}}}$ is a function of the sensitive attributes $\cA$ only. \[ass:gps\]

We will focus the discussion on


common cases in the literature. These include non-overlapping (unrestricted, intersectional), and overlapping (independent, gerrymandering) group partitions.

-   [*Unrestricted case.*]{} The simplest case is where the group is defined by a single sensitive attribute (when there are multiple sensitive attributes, all but one are ignored). These have been the primary settings addressed by past literature [@Hardt16; @Narasimhan18; @agarwal18]. Thus for some fixed $i \in [M]$, $g_{j} =\{(\bz, \ba)|a_i = j \}$, so $|\cG_\text{unrestricted}| = |A_i|$. In the special case of binary sensitive attributes, $|\cG_\text{unrestricted}| = 2$.

-   [*Intersectional groups*]{}. Here, the non-overlapping groups are associated with all possible combinations of sensitive features. Thus $g_\ba =\{(\bz, \ba')|\ba'=\ba\} \, \forall \ba \in \cA$ so $|\cG_\text{intersectional}| = \prod_{m \in M}|A_m|$. In the special case of binary sensitive attributes, $|\cG_\text{intersectional}| =  $\sum_{i=1}^{K}\sum_{j=1}^{K}b_{i,j}\conf_{i,j}$                   Demographic Parity      $(\mat{C}_{0,0}^g+\mat{C}_{1,1}^g - \mat{C}_{0,0}+\mat{C}_{1,1})-\nu$
  \[5pt\] Ordinal Acc.   $\sum_{i=1}^{K}\sum_{j=1}^{K}(1-\frac{1}{K-1} |i-j|)\conf_{i,j}$   Equalized Opportunity   $\left(\frac{1}{\omega_1^g}\mat{C}_{1,1}^g - \frac{1}{\omega^g}\mat{C}_{1,1}\right)-\nu$
  \[5pt\]


  : Examples of multiclass performance metrics and fairness metrics studied in this manuscript.[]{data-label="table-metrics"}

Bayes-Optimal Classifiers {#sec:bayesopt}
=========================

In this section, we identify a parametric form for the Bayes-optimal group-fair classifier under standard assumptions. To begin, we introduce the following general assumption on the joint distribution.

\[assumption1\] Assume $\mathbb{P}(\{ \vect{\eta}(\bx) = \mathbf{c} \}) = 0 \; \forall \mathbf{c} \in \Delta^K.$ Furthermore, let $Q= \vect{\eta}(\bx)$ be a random variable with density $p_{\eta}(Q)$, where $p_{\eta}(Q)$ is absolutely continuous with respect to the Lebesgue measure restricted to $\Delta^K$. \[ass:data\]

This assumption imposes that the conditional probability as a random variable has a well-defined density. Analogous regularity assumptionsgroup is weighed by group size, i.e., $
\max_{g\in\cG_\text{gerrymandering}} \frac{|g|}{n}|{{\widehat}{\mat C}}^g_{0, 1}+{{\widehat}{\mat C}}^g_{1, 1} - {{\widehat}{\mat C}}_{0,1}-{{\widehat}{\mat C}}_{1,1}|
$, so empty groups are removed, and small groups have relatively low influence unless there is a very large fairness violation. We denote the approach of @Kearns18 as `Kearns et al.` This approach is closely related to `Weighted-ERM` but searches for the maximally violated group by solving a cost-sensitive classification problem and uses fictitious play between $\lambda$ and $\vect h$. For the `Plugin` and `Weighted-ERM` approaches, we optimize the cost function directly using gradient ascent, precomputing the gerrymandering groups present in the data. Results are shown in Figure \[fig:gerry\]. We further present the differences in training time in Table \[tab:times\]. The results are roughly equivalent in terms of performance, however, both the `Weighted-ERM` and


`Plugin` approach are 1-2 orders of magnitude faster than `Kearns et al.`

Conclusion
==========

This manuscript considered algorithmic fairness across multiple overlapping groups simultaneously. Using a probabilistic population analysis, we present the Bayes-optimal classifier, which motivates a general-purpose algorithm, [[GroupFair]{}]{}. Our approach unifies a variety of existing group-fair classification methods and enables extensions to a wide range of non-decomposable multiclass performance metrics and fairness measures. Future work will include extensions beyond linear metrics, to consider more general fractional and convex metrics. We also wish to explore more complex prediction settings beyond classification.

Appendix {#appendix .unnumbered}
========

Bayes optimal
=============

[\[thrm:Min-Form\]]{} Under Assumption \[ass:gps\] and Assumption \[ass:data\], if , i.e., $$\vect{h}^* \in \argmin_{\vect{h}}\; \cE(\vect{h}) \;  \sut \; \cV(\vect{h}) \le \mathbf{0},$$ is feasible (i.e., a solution exists), the Bayes-optimal classifier is given by $\mathbf{h}^*(\bx) = \mathbf{h}^*(\bz, \ba) = \beta_{\ba}\mathbf{h}_1(\bx)Therefore we obtain the bounds $$\begin{aligned}
    &\cU_{\psi}(\bar{\vect h}^T) \leq \cU_{\psi}^*
    + \frac{JB}{\sqrt{T}}
    + ((1+J)B+1)\rho\left(4\sqrt{\frac{K^2\log(2n_{\min})}{n_{\min}}} + \sqrt{\frac{\log(2(1+|{\cG_{\text{fair}}}|)K^2/\delta)}{n_{\min}}}\right) \\
    &\qquad\qquad\qquad\qquad + \E \|\beeta(x)-\hat\beeta(x)\|_1B\left(\rho_{\cX }+\sum_{g\in{\cG_{\text{fair}}}}+ \frac{\rho_g }{\pi_g}\right) + 2\sqrt{\frac{\log(|{\cG_{\text{fair}}}|/\delta)}{n}}\sum_{g\in{\cG_{\text{fair}}}}\frac{\rho_g B}{\pi_g^2}\\
    &\|\cV_{\Phi}(\bar{\vect h}^T)\|_{\infty} \leq \frac{2J}{\sqrt{T}}
    +4(4(1+J)+1)\rho\left(\sqrt{\frac{K^2\log(2n_{\min})}{n_{\min}}} + \sqrt{\frac{\log(2(|1+|{\cG_{\text{fair}}}|)K^2/\delta)}{n_g}}\right) \\
    &\qquad\qquad\qquad\qquad + 4\E \|\beeta(x)-\hat\beeta(x)\|_1\left(\rho_{\cX}+\sum_{g\in{\cG_{\text{fair}}}}\frac{\rho_g}{\pi_g}\right) + 8\sqrt{\frac{\log(|{\cG_{\text{fair}}}|/\delta)}{n}}\sum_{g\in{\cG_{\text{fair}}}}\frac{\rho_g}{\pi_g^2}.\end{aligned}$$

Estimators
==========

In this section, we give plugin and weighted ERM methods of solving the linear probabilistic minimization problems arising from the Lagrangian of our fairness problem. For clarity, we go over the choices of cost and constraint matrices corresponding to what we use in our experiments.

In our experiments, we maximize accuracy while enforcing independent demographic parity constraints and group-weighted gerrymandering demographic parity constraints. Under the framework of our


$\P(g)$’s will cancel out with the $\P(g)$’s in the expressions below.

Plugin Estimator
----------------

Using linearity of $\psi$ and $\phi$, if $\eta$ is known, the population minimizer $h^* = \argmin_{h:\cX\to[K]} \cL(h, \lambda)$ is deterministic and has a convenient closed form solution (the same is true of any linear minimization). $$\begin{aligned}
\cL(h,\lambda)&=\langle\bD+\sum_{l=1}^L\lambda_l\bU_l, {\mat C}[h]\rangle-\sum_{g\in {\cG_{\text{fair}}}}\sum_{l=1}^L \lambda_l\ip{\bV_l^g, \vec C^g[h]}
\\
&=
\E\bigg\{\langle\bD+\sum_{l=1}^L\lambda_l\bU_l, \beeta(x)\vect h(x)^\top\rangle-\sum_{g\in {\cG_{\text{fair}}}}\sum_{l=1}^L \lambda_l\big\langle\bV_l^g, \frac{\1_{\{x\in g\}}}{\P(g)}\beeta(x)\vect h(x)^\top\big\rangle\bigg\}\\
&=\E\beeta(x)^\top\big[\bD + \sum_{l=1}^L \lambda_l\bigg(\bU_l-\sum_{g\in{\cG_{\text{fair}}}}\frac{\1_{x\in g}}{\P(g)}\bV_l^g\bigg)\big]\vect h(x).\end{aligned}$$ where we noticed that the conditional group confusion equals $\vec C^g[h] = \E\1_{\{x\in g\}}\beeta(x)\vect h(x)^\top/\P(g)$. Denote $\pi_g = \P(g)$ for $g\in{\cG_{\text{fair}}}$ as the group probabilities. Thus, the minimizer has the deterministic form $$\begin{aligned}
    h^*(x) &= \argmin_{k\in\{1,\ldots, K\}} \bigg\{\eta(x)^\top\big[\bD + \sum_{l=1}^L \lambda_l\bigg(\bU_l-\sum_{g\in{\cG_{\text{fair}}}}\frac{\1_{x\in g}}{\P(g)}\bV_l^g\bigg)\big]\bigg\}_k.
    \label{eq:plugsol}\end{aligned}$$ Finally, since we do not actually have access to the true $\beeta$, weMaternal separation disrupts the integrity of the intestinal microflora in infant rhesus monkeys.
The integrity of the indigenous microflora of the intestines after maternal separation was investigated in infant rhesus monkeys to determine whether psychological stress may lead to an internal environment conducive to pathogen infection. The stability of the indigenous microflora were estimated by enumeration of total and gram-negative aerobic and facultatively anaerobic bacterial species, specifically Lactobacilli, from coprocultures taken before and after maternal separation. In addition, behavioral and cortisol responses to separation were correlated to the microflora. A significant decrease in fecal bacteria, especially Lactobacilli, was evident on day 3 postseparation, with a return to baseline by the end of the week. The drop in the microflora was correlated with the display of stress-indicative behaviors, but not


small radial extent, often marginally resolvable by optical interferometry [@lazareff2017], scattered light imaging of the outer disk can indirectly reveal the presence of a misaligned inner disk. In this scenario, depending on the misalignment angle, the outer disk image will show narrow shadow lanes [e.g., @pinilla2015; @stolker2016; @benisty2017; @casassus2018], broad extended shadows [@benisty2018] or low amplitude azimuthal variations [@debes2017; @Poteet2018]. In some cases, studies of the CO line kinematics support a misalignment between inner and outer disk regions [@loomis2017; @perez2018]. The exact origin of such a misalignment is still unclear. In the case of T Tauri stars, if the stellar magnetic field is inclined, it can warp the innermost edge of the disk, which would then rotate at the stellar period [AATau; @bouvier2007]. Alternatively, inner and outer diskand shadows; @price2018].

In this paper we focus on the protoplanetary disk around the young intermediate mass star HD139614, located at a distance of $\sim$135pc [@gaia2018]. This A7V spectral type star has an estimated mass of $1.5\pm0.1$ M$_{\odot}$ and an age of $15.6\pm4$ Myr [@fairlamb2015], and it is not known to have any binary companions. The spectral energy distribution (SED) shows a dip at mid infrared (IR) wavelengths, evidence for a dust depleted inner region. The inner disk was resolved by the Very Large Telescope Interferometer (VLTI) at near and mid-IR wavelengths [@matter2014], indicating the presence of dust in the innermost region. These observations, supported by radiative transfer models of the SED and visibilities, allowed to infer the presence of a gap between 2.5 and 6astronomical units (au) [@matter-2016].


to prevent saturation and to ensure the smallest possible inner working angle.

The last observation epochs, performed in 2018, include detector dithering to reduce the effect of bad pixel and flat fielding errors (this mode was only offered recently for DPI observations). Observing conditions were fair during the coronagraphic observations with average seeing values in the visible between 0.8arcsec and 0.9arcsec and reasonable atmosphere coherence time above 2.4ms. The conditions were worse for the non-coronagraphic observations with a seeing of 1.1arcsec and a short coherence time of 1.5ms. However, even in these conditions a reasonable adaptive optics performance was achieved with several diffraction rings of the stellar point spread function (PSF) visible.

  Date            Filter   making this single shadow broader. Similarly, the asymmetry observed in the ring at $\sim$16 au requires an inner component to be misaligned. The fact that the peaks of the azimuthal profiles of the ring and outer (r>30au) disk are offset by $\sim$120 deg rather than 180 deg supports this hypothesis.

The inclination and PA of these components can be well-constrained not just by the location of the shadows they cast, but also by the slope/shape of the azimuthal profile peak of both the outer disk and the ring. While it is possible to produce a very similar azimuthal profile of the outer disk by interchanging the inclinations and PAs of both inner components, only one of these two configurations locates the peak of the azimuthal profile of the ring


@mulders2011. The 10$\mu m$ spectrum of HD139614 obtained with TIMMI2 at the ESO 3.6m telescope [@vanboekel2005] and with Spitzer [@juhasz2010] suggests that most of the silicate emission from this disk arises from a region corresponding to somewhere between the outer edges of zone 2 and the inner edge of zone 4 in our model. If this emission indeed originates from planet-induced shocks or planetesimal collisions, as theorized by @bouwman2003 and supported by the location of the gap as determined by @mulders2011, it would be consistent with the location of a hypothetical planet causing the warp or misalignment between components observed in the disk.

Conclusions
===========

Shadowing by different disk components in scattered light imaging is a powerful tool to infer the inner disk morphology. Several transitional disks have been shown tobrightest region partially overlapping with the darker region of the outer disk. []{data-label="fig:polar_projection"}](polar_centered.pdf){width="47.00000%"}

Azimuthal profiles
==================

Figure \[fig:azimuthal\_all\] shows the excellent fit of the brightness profiles between model and observations at all radii.

![Azimuthal profiles of the outer disk for both the combined dataset (black) and our model (red) at different radii. Each profile was measured in an annulus of width 4 pixels ($\sim$6.6 au) centered on the radius indicated on each subfigure.[]{data-label="fig:azimuthal_all"}](b1.pdf){width="50.00000%"}

\[lastpage\]

[^1]: Based on observations performed with SPHERE/VLT under program ID 096.C-0248(B) and 099.C-0147(B).


In a post yesterday on Hamburg Consumer Protection Centre, Ferrero, the Italian company that manufactures Nutella, confirmed changes to the formula for their world-famous chocolate spread. The amount of powdered skim milk rises from 7.5 percent to 8.7 percent, and the sugar content also increases from 55.9 percent to 56.3 percent.

All other ingredients—including palm oil—will stay as they are. As a result of the increases in sugar and skim milk powder, Nutella will be lighter in colour and taste sweeter.

Despite Ferrero assuring consumers in a statement that "the quality [...] and all other aspects of Nutella remain the same" following its recipe change, Nutella addicts aren't taking the news well. Many took to Twitter to share their dismay at the changes to what they perceive to be anStory highlights

Myls Dobson, 4, died after being beaten, burned and starved in her care, prosecutors say

The medical examiner concluded that Myls died from "child abuse syndrome including dehydration"

A caretaker who allegedly inflicted "unimaginable pain" in the final weeks of a 4-year-old boy's life has been indicted on a murder charge in his death, prosecutors said Thursday.

The second-degree murder indictment against Kryzie King, 27, comes five months after she allegedly beat and tortured little Myls Dobson while the boy was in her care in a Manhattan apartment, prosecutors said. She pleaded not guilty during an arraignment Thursday, according to District Attorney Cyrus Vance.

The murder charge was added after the medical examiner's office concluded in April that Myls died from "child abuse syndrome including dehydration," said Julie Bolcer, spokeswoman for


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                      = 0 (0)
00:00:03.131 NX - No-Execute Page Protection        = 0 (1)
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00:00:03.131 AXMMX - AMD Extensions t

A:

I've uncovered the mystery.  In the BIOS for the M4400, there are 3 options for virtualization.  One of those options is called "Trusted Execution" which I had turned on.  Even though my TPM was enabled, for some reason this setting was causing the system to not recognize VT-x.  Once I disabled                               -4-
defendant, such as Moore, from challenging prior convictions that

occurred before 1984, but are subsequently used to sentence a

defendant       as   a    habitual      offender,        "may    not    be   considered       an

independent and adequate state ground to bar federal relief."

Sones, 61 F.3d at 418 n.14.                 The court reasoned that


in

enforcing its laws."        Id.

     The Coleman Court noted there are also comity concerns that

arise when the independent and adequate state law ground is a

procedural default.

     This Court has long held that a state prisoner's federal
     habeas petition should be dismissed if the prisoner has

                                            -6-
     not exhausted available state remedies as to any of his
     federal claims. I have a set of BBC RC's 8.5x18 et 13 front and 10x18 et 25 rear, center bore is 74.1. It came off from a '98 BMW 540i. The wheels have no bends or cracks however the rears have scratches as well as the caps. Tires are Michelin Pilot Sport 365/40/18 front with 60% thread and 265/40/18 rear with 40% thread. Price is $1,100 + shipping.


Slideshow ( 2 images )

WASHINGTON (Reuters) - A 2017 tax overhaul championed by President Donald Trump will cut household taxes more in Republican-leaning states than in states that lean Democratic, according to research published by the U.S. central bank on Tuesday.

The Tax Cut and Jobs Act, signed by Trump in December 2017, reduced tax rates for most Americans, boosting economic growth in 2018 while widening the federal budget deficit.

Trump has often cited the legislation one of his key achievements, although critics say the law mostly cuts taxes for high-income Americans and corporations. Many Americans are also getting smaller tax refunds or owed money than in the past.

The tax law’s long-term effects will include pushing after-tax incomes 1.6 percent higher in states that tend to vote for Trump’s Republican               } else {
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have small inner lips) or the porn stars have had surgery. Every vulva is unique—like a beautiful snowflake. Love your vulva and take pride in your labia. I am saddened to have to even write this. Too many women have been the victim of rape, , and sexual coercion and I want these women to know: It is not your fault. EVER. Even if you were drunk. Most young women get drunk at some point in their lives—and you getting drunk doesn’t cause sexual violence. The perpetrator is the cause. Also, if you are a survivor, you can reclaim your sexual life again. The Sexual Healing Journey is a great starting point. Source: www.prestondrivered.com Finally, sex is a learnable skill not something people are inherently good or badtheir structurally diverse *N*-(hetero)aroyl derivatives were evaluated for in vitro antiproliferative activity. The discovered *N*-acylbenzenesulfonamide **4c** shows promising anticancer activity toward 50 human cancer cell lines and could be considered as a lead for further optimization.

Experimental {#Sec6}
============

Melting points were determined with a Boëtius apparatus. Infrared (IR) spectra were taken using a Thermo Mattson Satellite FTIR spectrophotometer, ^1^H and ^13^C nuclear magnetic resonance (NMR) were taken with a Varian Gemini 200 MHz or Varian Unity Plus 500 MHz spectrometer. Chemical shifts are reported in ppm ($\documentclass[12pt]{minimal}
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                \begin{document}$$ \delta $$\end{document}$ = 10.93, 122.02, 130.75, 134.08, 134.21, 135.74, 140.77, 161.04, 165.08 ppm.

General procedure for the synthesis of **2a**--**2d** {#Sec8}
-----------------------------------------------------

To a suspension of the appropriate 2,4-dichlorobenzenesulfonamide **1a**, **1b** (5 mmol) in 30 cm^3^ MeCN and 0.1 cm^3^ water, 1.52 g K~2~CO~3~ (11 mmol) and 0.016 g TBAB (0.05 mmol) were added. The obtained reaction mixture was vigorously stirred under an argon atmosphere, and slowly the appropriate mercaptan (5 mmol) was added dropwise. After 24 h of stirring at room temperature, the reaction mixture was concentrated under reduced1,490, 1,440, 1,350, 1,333, 1,162 cm^−1^; ^1^H NMR (500 MHz, DMSO-*d*~*6*~): $\documentclass[12pt]{minimal}
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                \begin{document}$$ \delta $$\end{document}$ = 4.51 (s, 2H, SCH~2~), 7.30--7.76 (m, 12H, H-3 and Ar--H), 8.35 (s, 1H, H-6) ppm; ^13^C NMR (50 MHz, DMSO-*d*~*6*~): $\documentclass[12pt]{minimal}
                  \begin{document}$$ \delta $$\end{document}$ = 36.26, 118.90, 119.01, 126.03, 127.87, 128.46, 128.72, 128.96, 129.25, 129.50, 132.64, 135.75, 137.16, 137.65, 144.38, 155.74, 159.68 ppm.

### *4*-*Chloro*-*2*-*(4*-*chlorobenzylthio)*-*5*-*(1,3,4*-*oxadiazol*-*2*-*yl)*-*N*-*(thien*-*2*-*ylcarbonyl)benzenesulfonamide* (**4d**, C~20~H~13~Cl~2~N~3~O~4~S~3~) {#d30e4151}

To a solution of 0.128 g thiophene-2-carboxylic acid (1 mmol) in 3 cm^3^ dry MeCN, 0.192 g EDCI (1 mmol) was added and stirred at room temperature for 5 min. **2c** (0.416 g, 1 mmol) and 0.184 g DMAP (1.5 mmol) were added and stirred at room temperature for 18 h. The reaction mixture was acidified with 2 cm^3^ 10% *p*-TSA/MeCN and concentrated under reduced pressure, and the residue was chromatographed with CH~2~Cl~2~/MeOH/AcOH (97:1:2) on silica gel column giving pure **4d**. Yield: 0.248 g (47%); *R*~f~ = 0.16 (benzene/EtOH = 4:1); m.p.: 205--207 °C; IR (KBr): $\documentclass[12pt]{minimal}
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(1 mmol) in 3 cm^3^ dry MeCN, 0.192 g EDCI (1 mmol) was added and stirred for 5 min. **2b** (0.396 g, 1 mmol) and 0.184 g DMAP (1.5 mmol) were added and stirred at room temperature for 18 h. The obtained solution was concentrated under reduced pressure, and 2 cm^3^ 10% *p*-TSA/EtOH was added with vigorous stirring. The obtained suspension was left in the refrigerator overnight. The formed crystalline solid was filtered off and washed with cold EtOH. Yield: 0.213 g (42%); m.p.: 230--231 °C; *R*~f~ = 0.17 (benzene/EtOH = 4:1); IR (KBr): $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
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   \begin{document}$$ \delta $$\end{document}$ = 35.64, 118.22, 127.52, 128.39, 128.81, 129.01, 129.37, 132.56, 133.56, 134.98, 135.25, 135.75, 136.51, 136.62, 143.19, 154.91, 159.11, 160.73 ppm.

### *2*-*Benzylthio*-*4*-*chloro*-*5*-*(1,3,4*-*oxadiazol*-*2*-*yl)*-*N*-*(pyridine*-*3*-*carbonyl)benzenesulfonamide* (**4h**, C~21~H~15~ClN~4~O~4~S~2~) {#d30e4701}

To a suspension of 0.135 g pyridine-3-carboxylic acid (1.1 mmol) in 5 cm^3^ dry MeCN, 0.212 g EDCI (1.1 mmol) was added and stirred for 5 min at room temperature. **2a** (0.382 g, 1 mmol) and 0.184 g DMAP (1.5 mmol) were added and stirred for 18 h at room temperature. The precipitate was filtered off, washed with MeCN, and then suspended in 1 cm^3^ EtOH, acidified with 1 cm^3^ 10% *p*-TSA/EtOH, and stirred for 2 h at room temperature. The precipitate was filtered off, washed with EtOH, and purified by extraction of contaminants with hot MeCN. Yield: 0.122 g (25%); m.p.: 282--284 °C; *R*~f~ = 0.30 (benzene/EtOH = 4:1); IR (KBr): $\documentclass[12pt]{minimal}


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                \begin{document}$$ \bar{\nu } $$\end{document}$ = 3,162, 3,080, 2,929, 2,854,\usepackage{mathrsfs}
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                \begin{document}$$ \delta $$\end{document}$ = 36.01, 56.38, 60.45, 106.49, 118.49, 125.99, 127.87, 128.74, 129.39, 134.16, 134.79, 135.32, 136.94, 142.05, 143.73, 152.93, 155.25, 161.05, 164.81 ppm.

NCI in vitro anticancer screen {#Sec11}
==============================

As of early 2007 all compounds submitted to the NCI-60 cell screen are tested initially at a single high dose (10 μM) in the full NCI-60 cell panel representing human leukemia, melanoma and lung, colon, brain, breast, ovary, kidney, and prostate cancers. Briefly, the compounds were solubilized in DMSO and added at a single concentration, and the


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community. As Kurdistan moves through this process, it is important to bear in mind that contrary to the prevailing public commentary, Kurdistan’s initial step of holding an independence referendum is not inconsistent with international law.

Dr. Paul Williams holds the Rebecca I. Grazier Professorship in Law and International Relations at American University and is the co-founder of the Public International Law & Policy Group (PILPG). He is a leading world expert in peace negotiations, post-conflict constitution drafting, and war crimes prosecution. In the course of his career he has assisted in over two dozen peace negotiations and post conflict constitutions.

Margaux J. Day is Senior Counsel at Public International Law & Policy Group, where she works on matters in Iraq, Sudan, Syria, and Yemen. Ms. Day previously was the DeputyChief Compliance Officer of Diebold Nixdorf, an Associate at the law firm of Jones Day, and an Adjunct Professor at Case Western Reserve University School of Law. She earned her juris doctorate from Case Western Reserve University School of Law.


Monday, August 30, 2010

Glenn Beck remarked during the 8-28 "Restoring Honor" rally that he believed this was the largest attended private event in Washington DC history. My wife and I attended both the 9-12 March on Washington in 2009 and this past weekend's 8-28 rally. From my subjective analysis, I believe it can be shown that the attendance at the Glenn Beck rally was roughly equivalent to the 9-12 march, which was estimated to be approximately 1.5 million people. It is possible that the 8-28 rally had the potential to be even bigger. All DC hotels were sold out during both of these events. On neither of these dates were there any other large events taking place which would have significantly competed for hotel space (other than Aland links to other sites, all in one place to make all of this more accessible for your convenience.

Our Founding Fathers

Patrick Henry, Revolutionary Leader and Orator - The Bible is worth all the other books which have ever been printed.

Abraham Lincoln - 16th President - In regard for this Great Book, I have this to say, it is the best gift God has given to man. All the good the Savior gave to the world was communicated through this Book .

Recommended Books

Saving Freedom - Jim Demint

A Praying Life - Paul Miller

The American Patriot's Bible - Dr. Richard G. Lee

Common Sense - Glenn Beck

Liberty and Tyranny - Mark R. Levin

The 5,000 Year Leap-W. Cleon Skousen

Special Scripture

Psalm 119:45 - I will walk about in freedom for I have sought out


Live updates

Two men have been charged with money laundering offences after hundreds of thousands of pounds in cash was seized at Portsmouth continental ferry terminal.

Thomas Kent, 43, of Millers Way in Brighton and John Tague, 49, of Halsall, Ormskirk in Lancashire were arrested after a lorry that was about to leave the UK for Bilbao was stopped and searched. Border Force officials found £494, 525 inside the vehicle.

The two men appeared before Portsmouth Magistrates Court on Friday 7th June 2013. They have been bailed to appear before Portsmouth Crown Court on Friday 21st June 2013.

A haul of cocaine with an estimated value of £6 million has been seized by Border Force officers in Portsmouth.

They discovered the packages of cocaine in a refrigerated container which had been unloaded fromwere presumably different for particular SOM clusters.

Statistical tests {#sec011}
-----------------

We decided to explore the data at a lower typology level by comparing the biotic and abiotic variables between 1) the six sub-clusters of SOM output neurons and 2) the three sampling stations within each SOM sub-cluster. Because the SOM does not provide a statistical verification of the observed differences, the significance of differences between the SOM sub-clusters was assessed by the Kruskal-Wallis and *post-hoc* Dunn tests \[[@pone.0144109.ref046]\] in the Statistica package (Statistica 12, StatSoft, Inc.). The significance of differences between the three sampling stations was assessed with the Friedman test for multiple groups of dependent samples \[[@pone.0144109.ref046]\] in the XLSTAT package. The Kruskal-Wallis and Friedman tests are non-parametric (based on ranks) equivalents of the analysis of variance that allow


in cyanobacterial biomass were also visible for four sub-clusters when moving downstream (from ZA to TR); the most distinct of these increases were recorded for Sm, LSp/Sm and HunLSp/Sm. Chlorophyll *a* increased in three successive sub-clusters, LSp/Sm, Sm and HotSm, and the differences were more pronounced downstream ([Fig 8](#pone.0144109.g008){ref-type="fig"}, [Table 1](#pone.0144109.t001){ref-type="table"}).

![Density/biomass variables presented directly to the Kohonen artificial neural network.\
Biomass of cyanobacteria (a-c), densities of *Daphnia longispina* (d-f) and *Leptodora kindtii* (g-i) at the Zarzęcin (a, d, g), Bronisławów (b, e, h) and Tresta (c, f, i) stations. Explanations are the same as in [Fig 7](#pone.0144109.g007){ref-type="fig"}.](pone.0144109.g008){#pone.0144109.g008}

10.1371/journal.pone.0144109.t001

###### Spatial differences (between the three sampling stations) in biotic variables and water temperature.

![](pone.0144109.t001){#pone.0144109.t001g}

  Variable and SOM sub-cluster   ZA     BR     TR these animals corresponded to the classical coupled system of predator and prey oscillations observed in other lakes \[[@pone.0144109.ref068]\]. Thus, the SOM results confirmed that the abundance of *Daphnia* was regulated by the predation of *L*. *kindtii* during summer. However, because the peaks in *Leptodora* density were short in duration and their frequency was different within the studied years ([Fig 3](#pone.0144109.g003){ref-type="fig"}), the precise estimation of *L*. *kindtii* pressure on daphniid population dynamics should be measured individually for each season. Analysis of the correlation matrices revealed that *Leptodora*, similar to *Daphnia*, avoided summer blooms. Interestingly, there was also a positive influence of increased inflow on *L*. *kindtii* density ([Table 5](#pone.0144109.t005){ref-type="table"}). The positive correlation between inflow and *L*. *kindtii* density might be related to the increased turbidity of the water during


essential in the development of management and policy decisions regarding the protection of ecosystems \[[@pone.0144109.ref072]\]. The application of an SOM in our research allowed the determination of a cause-and-effect understanding of the relationship between selected biotic and abiotic parameters. The importance of hydrology (flow rate, retention time, water-level fluctuations, etc.) as a plankton-regulating factor may be essential for the formulation of management decisions in dam reservoirs. This mainly refers to the regulation of retention time with respect to the control of the seasonal dynamics of large grazers, such as *Daphnia* spp., and/or as a tool for decreasing the occurrence of algal blooms. This method is especially recommended for anthropogenically modified ecosystems with toxic cyanobacterial blooms \[[@pone.0144109.ref028]\].

Supporting Information {#sec019}
======================

###### The 412 sampling terms assigned to the 24 SOM outputknowledge, we present the first realistic data augmentation for automotive ultrasonics. The performance of cGANs allows us to bring the realistic environment simulation to a new level. By using setup and environmental parameters as condition, the proposed approach is flexible to external influences. Due to the low complexity and time effort for data generation, we outperform other simulation algorithms, such as finite element method. We verify the outstanding accuracy and realism of our method by applying a detailed statistical analysis and comparing the generated data to an extensive amount of measured signals.'
author:
- |
    Maximilian Pöpperl, Raghavendra Gulagundi, Senthil Yogamani and Stefan Milz\
    Valeo Schalter und Sensoren GmbH\
    Kronach, Germany\
    maximilian.poepperl@valeo.com
bibliography:
- 'IEEEabrv.bib'
- 'biblio\_traps\_dynamics.bib'
title: '**Realistic Ultrasonic Environment Simulation