a greater awareness among the Pentagon's brass, as well as mandatory annual training to snuff out sexual abuse and usher in an era of openness in the military, the problem has only gotten worse.

USA TODAY interviewed lawmakers, social scientists and people who have worked on the sexual assault issue inside the military to determine why the Pentagon hasn't been able to stem this predatory tide. All pointed to two factors — one a new plague, the other as old as the military itself — standing in the way:

• A military culture more coarse toward women in the ranks, the result of stress from a decade of war and the status of women as second-class warriors barred from combat roles. Male recruits are drawn from a society where violenceallowed to serve openly in 2010, cultural attitudes had to be changed. In both cases, black troops and gay men were considered the legal equals of heterosexual, white males as combat troops.

The same has never been true for women. Though they constitute 15% of the military, they have always been legally relegated by Congress to non-combat roles. Only recently has the Pentagon begun to explore lifting that legal restriction.

"Some men still think ... women are inferior," says Bob Shadley, a retired Army major general who has published a book on sexual scandals he uncovered at Maryland's Aberdeen Proving Ground in the 1990s. "They don't fit in the male macho war-fighter image."

A TRADITION TWO CENTURIES OLD

American military justice evolved during the past century to closely resemble proceedings in a


historical era, weighing as much as 500 pounds. It looks as if mankind has been killing whole species on earth since the earliest times. Humans need to work out a way to live in peaceful co-existence with larger carnivorous species for the sake of ecosystems throughout the world. However, I live in the safety of the English countryside. No lions threaten my survival, no tigers roam around my village, taking human lives. It's the people who live close to predators who face the daily threat. In their position, I wouldn't want the animals killed. I'd suggest removing them to a protected, possibly fenced in, area.

Another fascinating post, Francene! I appreciate the detail, and couldn't agree more about the importance of finding ways to live in harmony. The rippleseen to date:
ruby 1.9.3p125 (2012-02-16 revision 34643) [x86_64-linux]
10 times on string of size 2284879
                 user     system      total        real
original     4.180000   0.070000   4.250000 (  4.272856)
sergio       2.090000   0.000000   2.090000 (  2.102469)
dbenhur      1.050000   0.000000   1.050000 (  1.042167)


Jed Purcell hasn't added a story.

A three-member team will try to summit the tallest mountain in North America to raise funds and awareness for the EOD Warrior Foundation, which helps the casualties and families of EOD operators who have sacrificed the most over the last decade of conflict.

The climb kicks off May 11 in Talkeetna, Alaska, when the team will fly by ski plane to the base of the climb on the Kahiltna Glacier. From there, it's up to three weeks of hauling 120 pound gear loads up the West Buttress route in subzero temperatures until reaching the zenith of North America.

Explosive Ordnance Disposal operators have a dangerous job and The EOD Warrior Foundation has offered personalized support to more than 350 of those wounded and fallen herostraditional drawing, usually with black outlines and simplified color. This is a great format for those looking for a more modern or sleek image, or need a print-ready image. Great examples of this style are provided below, and more examples can be found in in thephotos above. Standard digital commissions start at $75 per person. Themes may result in additional fees based on complexity. If you would like the commission printed, additional fees will apply. Expedite fees will apply for any orders due within 2 weeks of order placement.


Clara in the off-Broadway revival of Passion at Classic Stage Company, Heidi in [title of show] for the regional premiere at Repertory Theatre of St. Louis, and four productions with City Center Encores. Amy's concert work includes Peep Bo in The Mikado at Carnegie Hall, Cinderella and Rapunzel in Disney on Classic with the Tokyo Philharmonic, covering Kelli O'Hara in Lucky to Be Me at New York City Opera, and Jessie in Mahagonny Songspiel at the Ravinia Festival. She has also been a soloist with the Baltimore Symphony Orchestra (Bernstein's Mass, recording on Naxos), New York City Ballet, Fire Island Opera Festival, Great Music in a Great Space, American Modern Ensemble, American Symphony Orchestra, the Kurt Weill Fest, American Opera Projects, Berkshire Bach Society, Broadway Chamber Players, Masterlimit. The rituals have a level, so for learning and launch a ritual, you need to be of the ritual level.

There are no complex rules here like tracking encumbrance. All is easy to understand, easy to teach, and open to quick and safe houseruling.

Conclusion

Beyond the Wall is really a nice game and my favorite OSR game at this time. The playbooks are incredibles and Flatland Games give us many free supplements for playbooks and scenario pack. The game is more a fantasy game than a sword & sorcery one, more Tolkienesque than D&D in my mind.

This game is an icredible concept. I have been gaming since the early 80s and have played more than systems than I can remember, Beyond the Wall hits SO many marks. Character creation


is actually FUN for once, that alone is a revelation! The idea that I as a GM can sit down with zero prep work and have a great scenario outline, with ties the the PCs, is a God send. I have run the same scenario pack multiple times with different results each time, even having run the same scenario pack for the same group of PCs. It isn't hard to comine scanrio packs to get interesting adventures, for instance I combined one of the undead related scenarios with one from the Goblin add one, it made for a fantastic adventure with lots of twists.

The system is essentially somewhere between OD&D and Moldvay-era Basic/Expert D&D, with some modern mechanics thrown in (ascending AC for instance). I have run thewe have played through a scenario for which I had done almost no prep (15-20 min spent after the character generation session).

All of the players came away ravong about what a good time they had had and immediately asked when they could play it again because there were still so many areas fo their characters and the village that they wanted to explore. For example, who were the mysterious mercenaries that had come looking for one of the characters in the past and what did they want with them?

This group will be going back to the village of Last Wall again and again I feel.

This game is amazing!!!!! So glad I found it, wish it would've been sooner. My gaming group has been turning into a bunch of


of playbooks doesn't mean it doesn't have good ol' fashion roll your stats and pick your class character creation. And here's where it gets better smooth. With only three classes, Warrior, Mage and Thief with limitless options for hybridzing the classes (with proper GM discussion of course) making the kind of character you want to play is quick and virtually painless.

I don't think I'll be drinking deep of the well of OSR games myself but this particular game is going to be one of my go to systems for the kind of coming of age, small scale fantasy adventures that I adore.

We had a blast playing this.
I was pretty new to GMing PbtA games when we tried this. It pretty rules light - when compared to some ofThe problem here is tight coupling in classes. In other words, "class A depends on class B". Let's take an example and try to understand the tight coupling.

Suppose we have a Samsung class that contains an Android class object. An issue with this is tight coupling between classes. In other words the Samsung class depends on the Android object. So if the Android class changes for any reason then it may affect the Samsung class.

The problem is that the Samsung class controls the creation of the Android object.

The Android class is directly referenced in the Samsung class that leads to tight coupling among address and customer objects.

If we make any changes to the Android class then it might affect the Samsung class also, because the Samsung class is


Job Detail # PIPE FABRICATOR

Construction (Fabricator)

Job Description

Has experience in P & C projects for minimum 10 years in this
position
2. Should know how to read isometrics & other drawings.
3. Should have familiar with different type of piping materials.
4. Should have skill to make piping joints using Jigs & fixtures within
standard time frame.
6. Ensure to meet safety awareness in P&C projectstools to broadcast and record news, they’re (citizens) now owning the part that the news distribution channels used to have.

“But the explanation of those events is still fundamentally where the journalists come in,” he continues. “It makes journalism a lot more important. In fact, there are more journalists today, working and explaining the world to us than there has been at any other time. Journalism has never been stronger. The recording of the news is where the new technologies come into play, but we conflate these two concepts and think that they’re both reporting. But that’s not the case.”

Broadcasting the banal

So many people now feel the need to broadcast every facet of their life on Twitter, a habit journalists aren’t impervious to either.

“I think that if I look


this extends beyond Twitter and into all forms of computer-based interaction – is that it can be easy to slip into a comfy life behind a desk. Why should you head out and film events yourself and speak to people, if you’ve got a thousand citizens already pointing their iPhones at a scene and uploading it to YouTube?

A whole lot of information is missed by not being out there and speaking to people. “You have to be there,” says Lewis. “You probably get about 10% of a story if you’re not there. It’s very difficult to convey how much more valuable it is to be out there on the ground, but any professional journalist will tell you how important it really is.”

Ketelaar agrees, citing a recent example whenknown as journalism, is priceless. But feeding into this, is the well-oiled social machine that lets real-time information flow so freely. Modern day journalism isn’t about ‘traditional vs. new’, it’s about traditional AND new.

“I probably thought a year ago, from a technology and social media point of view, that journalism’s dead…we’ve got the social Web now, right?,” says Butterworth. “But one thing I’ve learned over the past year is the value of journalism, and I think it’s very different to the kind of information we get on social media.”


Q:

Run code in ViewController from App Delegate

In my appDelegate.m I'm running this:
- (BOOL)application:(UIApplication *)application handleOpenURL:(NSURL *)url {
    NSLog(@"url recieved: %@", url);
    NSLog(@"query string: %@", [url query]);
    NSLog(@"host: %@", [url host]);
    NSLog(@"url path: %@", [url path]);
    NSDictionary *dict = [self parseQueryString:[url query]];
    NSLog(@"query dict: %@", dict);
    if([[url host] isEqual: @"success"]){
        RegistrationController *rc = [RegistrationController alloc];
        [rc regSuccess];
    }
    else if([[url host] isEqual: @"fail"]){
        RegistrationController *rc = [RegistrationController alloc];
        [rc regFailed];
    }
patent, the court dismisses plaintiff’s complaint.
                                       I. BACKGROUND
        Plaintiff is the inventor and owner of U.S. Patent No. 6,552,654 (“’654 patent”),
“Security System with a Mobile Telephone.” The patent expired on April 22, 2007, “due to Mr.
Gharb’s non-payment of the maintenance fees required under 37 C.F.R. § 1.362.” Unitronics
(1989) (R “ G) Ltd. v. Gharb, 532 F. Supp. 2d 25, 26 (D.D.C. 2008). In his complaint, plaintiff
alleges that various corporations, including principally Mitsubishi Electric Corporation
(“Mitsubishi Electric”), have violated his patent. The caption of his


U.S. 544, 570 (2006)). While a
complaint under RCFC 8(a) need only set forth a “short and plain statement of the claim,” the
United States Supreme Court “explained in Twombly that while Rule 8 does not require ‘detailed
factual allegations,’ it does require more than ‘labels and conclusions.’” Sioux Honey Ass’n v.
Hartford Fire Ins. Co., 672 F.3d 1041, 1062 (Fed. Cir. 2012) (quoting Twombly, 550 U.S. at
555). “Deciding whether a complaint states a plausible claim for relief will . . . be a context-
specific task that requires the reviewing court to draw on its judicial experience and common
sense.” Iqbal, 556 U.S. at 679. “A claim has facial plausibility when the plaintiff pleads factual
content that allows the court to draw the reasonable inference that the defendant is liable for the
misconduct alleged.” Id.government contracts held by Mitsubishi Electric. But plaintiff
has not made any allegation that the government contracts at issue required the government to

                                                  4
purchase PLCs. The information provided in plaintiff’s response only indicates that the
government had entered into contracts with Mitsubishi Electric, and does not identify particular
contracts. See Pl.’s Resp. 2-3. Without more, plaintiff has not met the requirements of
Twombly and Iqbal of providing sufficient factual content to allow the court to conclude that
Mitsubishi Electric “used or manufactured” plaintiff’s patent


may actually be endometriosis? Unfortunately, the answer isn’t that simple.

IBS requires a “diagnosis of elimination,” meaning doctors have to rule out other causes before they come to a final determination. Often, we will perform a battery of tests, including blood tests, lactose intolerance tests and a colonoscopy, to first eliminate other health conditions. To be diagnosed with IBS, you must experience discomfort for at least three days during the last three months and you must have bowel symptoms for at least six months before you can get a medical exam.

Though IBS shares similar symptoms to endometriosis (and bowel endometriosis, in particular), the two conditions do differ in some ways.

One study that compared the two conditions found that women with IBS were more likely to alternate between constipation andmuseum in New York and put some on sale. What was left apparently cost only $6m and the Islamic republic exchanged de Kooning's painting for that. If they were really interested in the Shahnameh, couldn't they pay $6m and keep de Kooning's painting? The US businessman David Geffen, who bought the painting for some $20m, sold it for some $110m few years ago. The de Kooning exchange is the sole exchange they've done so far and I hope it remains the last one.

I follow the works of Iranian artists even now, sometimes in Paris or in New York and I am happy Iranian artists are still great. Whether they are men or women, they have always been great. Despite all the pressure and censorship inside the country, they


Q:

Conditionally use a REGEXP in MySQL

I'm trying to conditionally match against a REGEX.  If the REGEX is blank, it is a match, otherwise, match against the REGEX.  Currently I have tried the mySQL IF function, CASE statement, and logical operators with no success.  This is on MySQL 5.6.12.  The error I am getting is:
ERROR 1139 (42000): Got error 'empty (sub)expression' from regexp

Here are some statements showing my issue.
SET @test = '';
SELECT (@test = '' || ('abc123' REGEXP @test)) AS matches;
SELECT (true || ('abc123' REGEXP @test)) AS matches;
SELECT IF(true, true, 'abc123' REGEXP @test) AS matches;
SELECT (CASE WHEN true THEN true ELSE 'abc123' REGEXP @test END) AS matches;

I would have expected the operators precedence order to return true in all these statements.  Is thereIntroduction {#tri13486-sec-0001}
============

Kidney transplantation is often the treatment of choice for a proportion of patients with end‐stage kidney disease (ESKD), conferring a significant survival advantage and improvement in quality of life compared to dialysis treatment [1](#tri13486-bib-0001){ref-type="ref"}, [2](#tri13486-bib-0002){ref-type="ref"}. Advances in the management of cardiovascular disease (CVD) have resulted in a substantial reduction in CVD mortality in kidney transplant recipients, but despite improved access to cancer screening and novel treatment options, cancer remains a major cause of morbidity and mortality in this population [3](#tri13486-bib-0003){ref-type="ref"}, [4](#tri13486-bib-0004){ref-type="ref"}. In Australia, cancer has surpassed CVD as the most frequent cause of mortality in kidney transplant recipients, with similar trends observed worldwide [4](#tri13486-bib-0004){ref-type="ref"}, [5](#tri13486-bib-0005){ref-type="ref"}. Even though cancer is a feared complication for kidney transplant recipients, many patients would still consider this as an acceptable risk in


cancer when it is first diagnosed. In addition, the standardized tumour, node and metastases (TNM) classification system, which considers in more details the size, nodal involvement and spread of the tumours (for breast cancer: stages IA, IB, IIA/B, IIIA--C and IV), provides a more accurate description and prognosis of the cancers. Other factors such as age, performance status, response to treatment and presence of certain tumour characteristics \[such as hormone receptor and human epidermal growth factor receptor‐2 (Her2) status for breast cancer\] will influence prognosis, further compounding the complex decision when determining whether patients with prior cancers are suitable for transplantation (Table [2](#tri13486-tbl-0002){ref-type="table"}). The current guideline recommendations are often based on low or ungraded quality of clinical evidence extrapolated from cohort studies and/or the opinions of the expertage‐ and gender‐matched general population, likely resulting from the chronic suppression of cell‐mediated immunity attributed to lifelong immunosuppressive therapy [7](#tri13486-bib-0007){ref-type="ref"}, [108](#tri13486-bib-0108){ref-type="ref"}, [109](#tri13486-bib-0109){ref-type="ref"}. There is consistent epidemiological evidence to suggest that kidney transplant recipients with melanoma have significantly higher Clark\'s level and pathological staging, with up to four times the risk of cancer mortality compared to the general population (Table [4](#tri13486-tbl-0004){ref-type="table"}) [12](#tri13486-bib-0012){ref-type="ref"}, [110](#tri13486-bib-0110){ref-type="ref"}. Consequently, clinicians are often reluctant to consider kidney transplantation in patients with prior history of melanoma, with those with invasive melanoma \[American Joint Committee on Cancer (AJCC) stage II and above\] considered absolute contraindication for transplantation. Given the improved survival and treatment options for patients with melanoma in the general community [111](#tri13486-bib-0111){ref-type="ref"}, there is considerable debate regarding the acceptability of patients with more advanced treated melanoma


                        Follow‐up 14 years postmelanoma. Interval from melanoma to transplant range: 0.4--33 years. Breslow thickness range: 0.5--18 mm (3 no records)
  Puza [121](#tri13486-bib-0121){ref-type="ref"} (2001--2016)          Duke University, US. All solid organs)              2 of 12 (median time 5.3 years). 1 *in situ* and 1 stage IIIA                                      = pathcoll.get_facecolors()
    facecolors[[a,b]] = facecolors[[b,a]]

    # Switch sizes
    sizes = pathcoll.get_sizes()
    sizes[[a,b]] = sizes[[b,a]]

    # Set the new offsets, facecolors and sizes on the PathCollection
    pathcoll.set_offsets(offsets)
    pathcoll.set_facecolors(facecolors)
    pathcoll.set_sizes(sizes)

switch_scatter(balls,2,1)

plt.savefig('balls_02.png')

Heres balls_01.png:

And here is balls_02.png (where we switch ball 1 and ball 2 (the blue and green balls)

A final note: if you have other properties varying in your scatter plot (e.g. linecolor), you will also need to switch them around in the function I defined above.


Three nail-biting gubernatorial contests in deeply red states have both Democrats and Republicans on edge in the two weeks before Election Day, in races that will test President Trump Donald John TrumpFederal prosecutor speaks out, says Barr 'has brought shame' on Justice Dept. Former Pence aide: White House staffers discussed Trump refusing to leave office Progressive group buys domain name of Trump's No. 1 Supreme Court pick MORE’s ability to move votes a year before his reelection bid.

Two incumbents, Kentucky Gov. Matt Bevin (R) and Louisiana Gov. John Bel Edwards (D), are on the ballot next month. In the third state, Mississippi, Republican Lt. Gov. Tate Reeves is facing off against Democratic Attorney General Jim Hood.

And in all three contests, polls show a tied race. The latest Mason-DixonThe present invention relates to an imaging and treatment head for imaging and treating organs or tissues of living beings, and usable in particular for treating various tumors, such as tumors of the thyroid, breast, or uterus. The present invention consequently relates to the field of therapy devices, and more particularly to therapy devices for performing therapy with ultrasound monitoring, and more particularly to therapy devices using power ultrasound. Treatment using focused power ultrasound is known under the acronym HIFU (High Intensity Focused Ultrasound).
The treatment and imaging head of the invention is for mounting on an arm provided with motors, so as to be able to displace the head accurately in various directions. The head is also connected to an electronic control and treatment cabinet, and to a


versa that the treatment means degrade or reduce the quality of the imaging means. It is thus necessary to find a compromise so as to have an image of sufficient quality for it to be usable, and treatment of sufficiently high performance for it to be able to treat the target correctly.
An object of the present invention is to propose a particularly advantageous configuration for the imaging means and for the treatment means, making it possible to obtain an image of quality that is as high as possible and treatment that is as effective as possible. Another object is for the focal point to be located precisely.
To achieve this object, the present invention proposes a head having imaging means that subdivide the treatment means, substantially in a mid-plane,As is well known and understood, government regulations more and more mandate the use of safety shields to afford protection to the operators of machine shop equipments. Usually positioned in use such that the shield is in the workman's line of sight to the piece being machined, these shields are generally made of a heavy plastic, see-through, material, bent to protect the worker, and oftentimes, those who may be in areas immediately adjacent to his. As is also well known and understood, however, there is much resistance to the use of these shields--one of the reasons being the inherent delay in having to continually adjust and re-adjust the shield positioning every time a workpiece is loaded onto, and removed from, the machine in question. Presently available safety shields


forget Brian [sic] Singer either.”

And then there was former The Real O’Neals star Noah Galvin, who in a since-deleted quote from an interview with Vulture, said: “Yeah. Bryan Singer likes to invite little boys over to his pool and diddle them in the f—ing dark of night. (Laughs.) I want nothing to do with that. I think there are enough boys in L.A. that are questionably homosexual who are willing to do things with the right person who can get them in the door. In New York there is a healthy gay community, and that doesn’t exist in L.A.”

The quote was later removed from the interview and Galvin issued an apology on Twitter: “I sincerely apologize to Bryan Singer for the horrible statement I made. My comments wereticket in JIRA

I go in JIRA and click “Start progress”

I create a new branch for my fix, also via JIRA

I git fetch and git checkout the new branch

and the new branch I open the relevant file(s) in Emacs and fix the problem

Go back to the browser and make sure the issue is gone

I press a few keybindings to commit and push via Magit

I go to Stash, locate the branch and click “Create pull request”

I go to JIRA and click “Ready for code review”

I paste the link to the pull request into our Skype group, just in case

... and then I wait for two other developers to review and approve my patch

only after that I can click “Merge” in Stash and my fix goes to master

I go to JIRA


Public awareness of warning signs and symptoms of cancer in oman: a community-based survey of adults.
The majority of deaths from cancer occur in low and middle income countries, partly due to poor public awareness of the signs and symptoms of cancer. A community based survey using the Cancer Awareness Measure (CAM) questionnaire was conducted in three different communities in Oman. Omani adults aged 18 years and above were invited to participate in the study. A total of 345 responded from 450 invited participants (response rate=76.7%). The majority of respondents were unable to identify the common signs and symptoms of cancer identified in the CAM (average awareness was 40.6%). The most emotional barrier to seeking help was worry about what the doctor might find (223, 64.6%); a practical barrierinterval, 94.4%-100%) and 83.3% (95% confidence interval, 79.0%-87.0%), respectively, whereas the positive (calculated from Bayes' theorem) and negative predictive values were, respectively, lower than 1% and 100% (95% confidence interval, 98.8%-100%). Positive and negative LR were 6.0 (95% confidence interval, 4.7-7.6) and zero, respectively. Our results suggest that LAT is a useful tool for the etiological diagnosis of pleural effusion. It is a reliable, rapid, simple to perform and shows an excellent yield in our studied population, helping to prescribe appropriate antibiotics for this clinical condition.


captures to Youtube and being able to cross-platform voice chat.

But that’s not all, Google Stadia has some huge plans for the service. Sometime in the future, Google suggests you’ll be able to play and stream on Youtube both in 4K. Or, it will allow starting a game by clicking on its Youtube ad. Finally, Google Stadia will be launching their own games. Yet, none of these plans have an estimated time frame.

So, will the release of Google Stadia be revolutionary? It looks like, Stadia will bring positive changes for our gamers on Youtube. With some impressive features, Youtube creators will be able to produce high-quality content and make your gaming experience better.plasma mass spectrometry (ICP-MS). The recovery ranged from 87.5 to 104.0% and a good agreement was achieved between both methods. The detection limit and the limit of quantification were 0.6 and 2.1 µg g-1 respectively. The precision of the method was confirmed by the determination of Ni in the spiked samples and was below 4%, expressed in terms of a relative standard deviation. The method was applied to the determination of nickel in production samples of active pharmaceutical ingredients and intermediates.


The primary structures of four subunits of the human, high-molecular-weight proteinase, macropain (proteasome), are distinct but homologous.
Macropain (proteasome) is a high-molecular-weight proteinase complex composed of at least 13 electrophoretically distinct subunits. Previous work, including peptide mapping and limited amino acid sequencing, suggested that most of the subunits belong to an evolutionarily related group of different gene products (Lee et al. (1990) Biochim. Biophys. Acta. 1037, 178-185). In order to define the extent and pattern of subunit relatedness, and to determine the structural basis for possible similarities and differences in subunit functions, we are deducing the primary structures of macropain subunits by cDNA cloning and DNA sequence analysis. We report here the primary structures of four subunits. The data clearly demonstrate that the proteins represent different, but homologous gene// get the default value for the fields
    var emailFieldDefault = emailField.val();
        var firstnameFieldDefault = firstnameField.val();
        var lastnameFieldDefault = lastnameField.val();

    // add a password placeholder field to the html
    passwordField.after('<input id="passwordPlaceholder" type="text" value="Password" autocomplete="off" />');
    var passwordPlaceholder = $('#passwordPlaceholder');

    // show the placeholder with the prompt text and hide the actual password field
    passwordPlaceholder.show();
    passwordField.hide();

    // when focus is placed on the placeholder hide the placeholder and show the actual password field
    passwordPlaceholder.focus(function() {
        passwordPlaceholder.hide();


need
This is just what you need:
http://plugins.jquery.com/project/input-placeholder
With it your code will look very clear and simple, like:
<input type="text" name="first_name" placeholder="First Name" />
<input type="text" name="last_name" placeholder="Last Name" />
<input type="text" name="email_address" placeholder="Email" />

<script>
   $(function(){
      $('input[placeholder]').placeholder();
   })
</script>

Instead all of your javascript

Influence of exercise on cancellous bone of the aged female rat.
Dual-energy x-ray absorptiometry and dynamic histomorphometry were used to examine the effect of treadmill exercise on the bone density and cancellous bone formation and resorption in the proximal tibia and fifth lumbar vertebra (L5) of the aged female rat. Female rats aged 14 months were divided into four groups: 8 controls and 10 exercised for a 9 week study and 8 controls and 9 exercised for a 16 week study. Exercise consisted of running on a flat-bed treadmill, 17 m/minute, 1 h/day, 5 days/week. Tibial metaphysis and L5 vertebral density of each rat were measured in the 16 week study by DXA at weeks 0, 9, and 16. Compared to the control group, a significant increase in bone


This invention relates to a flash exposure photocopying machine and, more particularly, to an automated system for controlling photoreceptor exposure in response to detection of original documents of varying color backgrounds.
In electrophotographic devices, such as a xerographic copier or printer, a photoconductive surface is charged to a substantially uniform potential. The charged portion of the photoconductive surface is exposed to a light image of an original document being reproduced, forming an electrostatic latent image at the photoconductive surface corresponding to the informational areas contained within the original document. The electrostatic latent image is subsequently developed by bringing a developer mixture into contact therewith. The developed image is then transferred to an output copy sheet and the powder image on the output sheet is heated to permanently affix thebest will in the world, her wish could not be met as the spa was full! I was stunned to hear this; after all, aren’t we still meant to be feeling the pinch from the economic decline? Yet... read more

Posted by Ellee on Apr 9, 2014 in Blog | 0 comments
Reading about Britain’s first cloned dog today reminded me of what the celebrated literary critic, Prof John Carey, said at the splendid Cambridge Literary Festival last weekend where he was giving his new book, The Unexpected Professor, a plug. He was asked to name his favourite contemporary author and the reply he gave, this lover of Milton and Shakespeare, was not what I expected. One... read more

Posted by Ellee on Mar 25, 2014 in Blog | 0 comments
I


133 in β-strand 12, and the remaining positions 134-135 appear largely disordered.7 Thus, these data are consistent with the N- and C-termini β-strand interaction representing a region of structural weakness in FGF-1 and therefore potentially contributing to the unfolding process. Of additional interest, quenched-flow hydrogen exchange experiments with FGF-1 have shown that the hydrogen bonds linking the N- and C-termini anti-parallel βstrands appear to be the first detectable event in the folding of FGF-1, and may provide a structural framework for subsequent folding events.8 Thus, in addition to unfolding, the interaction of the N- and C-termini β-strands may be a key contributor to the folding of FGF-1.
In an effort to study the contribution of the N- and C-termini β-strands to the stability and folding of FGF-1, Cys mutationswas 0.05 ng/mL with every 10 min increase in the CPB time. However, in those patients who had received CsA, this increase in cTNT was less with an average rise of only 0.02 ng/mL of cTnT. Therefore, patients who had received CsA had an attenuated increase in their average cTnT. [Figure 2](#HEARTJNL2013304845F2){ref-type="fig"} demonstrates that the slope of the average cTnT rise is significantly less in the group of patients who had been given CsA as compared with the control group.

######

Patient peri-operative serum CK-MB and troponin-T (cTnT) levels

                        CsA (n=40)    Control (n=38)   p Value
  --------------------- ------------- ---------------- ---------
  CK-MB (ng/mL)


models with primary or secondary resistance against abiraterone and was deemed one possible cause of resistance \[[@CR14]\]. The activation of these enzymes may enhance rescue pathways of testosterone and dihydrotestosterone (DHT) production in prostate cancer cells \[[@CR15]\] and thereby impair the efficacy of abiraterone.

Taken together, discontinuation of LHRH therapy during treatment with abiraterone may impair the efficacy of abiraterone and display an unpredictable hazard to patients leading to early progression, and consequently shortened cancer-specific and overall survival.

Investigation of the effects of discontinuing LHRH therapy at the time of initiation of abiraterone treatment therefore represents a major medical need, especially in view of the side effects of LHRH therapy. This will be the first study to assess the efficacy of abiraterone acetate in patients with CRPC randomized to continueor discontinue LHRH therapy. The results of this trial will contribute evidence to the understanding of castration- and hormone-resistant prostate cancer. Furthermore, this trial may add evidence to the current recommendation to continue LHRH therapy, thereby improving the benefit of abiraterone treatment for the patient. In order to enable comparison of the trial results to previous trials, the main aspects of the trial design are in close similarity to those of the COU-AA-302 trial protocol \[[@CR2]\].

Methods/design {#Sec2}
==============

Hypothesis {#Sec3}
----------

Given the risk that discontinuation of LHRH therapy patients, leading to early progression and consequent shortening of cancer-specific and overall survival between patients, leading to early progression and consequent shortening of cancer-specific and overall survival between study arms, this phase II study was designed. This is a two-arm, investigator-initiated, randomized controlled


across Germany. Accrual time for the trial is estimated to take 12 months.

Statistical analysis {#Sec17}
--------------------

Prior to locking the database, a data review is planned in order to review individual data and validate the Statistical Analysis Plan. All deviations from protocol definitions will be listed and defined as major or minor deviations.

Statistical analyses will be performed using eCRF data collected until a clinical cut-off date is reached that is defined when the number of events required for the final analysis of the efficacy variables is achieved. Unless otherwise specified, all continuous endpoints will be summarized using descriptive statistics, which will include the number of patients (*n*), mean, standard deviation, median, minimum, and maximum. All categorical endpoints will be summarized using frequencies and percentages. The baseline measurement will be the lastcontrolled trial

RECIST

:   Response Evaluation Criteria in Solid Tumors

rPFS

:   Radiographic progression-free survival

StAR

:   Steroidogenic acute egulatory protein

**Electronic supplementary material**

The online version of this article (doi:10.1186/s13063-017-2195-x) contains supplementary material, which is available to authorized users.

Not applicable

Funding {#FPar1}
=======

The trial is funded by a restricted research grant from Janssen-Cilag GmbH, Germany.

Availability of data and materials {#FPar2}
==================================

All data are fully available without restriction.

CHO, MJ, PJ, SK, JG, HR, and MS participated in the design of the study. CHO conceived the study and participated in its design and coordination. CHO and HR drafted the study protocol. PJ designed the statistical analysis. CHO drafted the manuscript and all authors read and approved the final manuscript.

Authors' information {#FPar3}
====================

CHO, SK and JG are board members of the working group on uro-oncology (AUO)


at OE put 60 in the wrong box.

I can't say for sure that it isn't. However, the data on the OE site is normally definitive and current. Using a fairly broad search, I can't find any location listing that test with a passing score of 60%. In my search, however, I found an interesting post on Code Ranch where people have created some study notes for the exam. Looking at them, they aren't illicit (i.e. brain dumps) and may well be useful to you.

Or you can ask friend #1 to look at his score report again. It's available as a PDF on Certview. However, that may not answer the question for sure. It will only eliminate one possible error. Currently there are three options that I can see:

1.love each other." "I thought you had forgotten!" "You are standing by the window long hours, you don't look after the labourers, don't mind our child!" " Stop it!" " I am your wife!" "What a wife!" "I made a bet I would get you!" "You were already engaged with Oliver." "Such is my wife!" "I fell among rose bushes." "Let us leave this place." "Let's sell everything and go away." "We cannot be better anywhere else." " Dear committee members!" " Let's listen!" " I wish everybody good health!" " Thank you." "Vintage is here." "We begin in a week's time." " Too late!" " You shut up!" "Accepted." "Cheers!" "Teacher, come here!" "Dontsin, serve yourself!" "He will, don't worry!" "Not from yours." "If it's free, you


treasurer and Urban will record and check everything!" "Vlcindol will advance faster!" "Father!" "Fast!" "Open!" "Ann, open!" "I don't want to see anybody!" "What is bothering you, daughter?" "You'd better ask who it was!" "What happened?" "I have already brought the action!" "That does not matter now." "All but the two of us are co-op members." "That would be some work for you, teacher." "I will be pleased." "Slivnicky has caused public outrage." "He dulls people's minds and pumps them for money." "You shut up!" "It is enough to describe it and send to the authorities." "Perhaps his Ann doesn't keep you from doing it." "Hereby I open the first meeting in the Co-operative Hall!" "From these sheets you will see how we managed." "First, a sad pieceof news." "Urban and Oliver got one month." "Thirty-one houses participated." "With 226 shares, having value of 11,300 crowns." "But building costs reached 20,000." " What did we need it for?" " To increase shares!" "Will our families graze?" "We don't want to increase shares!" "Shall we borrow from Silvester?" "The Economic Bank will give us a loan." "We could've done so individually!" "Bloody associations!" "Listen to me!" "Be quiet!" "Heaven forbid we lose faith in this!" "From the first moment, we know there are more problems here!" "Not only frost, hail, but annoyance and treachery as well," "Pancucha and Silvester, who..." "a waste of words!" "Will you marry my sister or not?" "No!" "I found this at the teacher's place." "Is he alive?" "He will be fit


be held!" "If necessary, I'll go and see the minister!" "The lords are here!" "The auction will be held!" " Shall we go?" " To see our own funeral?" "In the name of the law, all leave!" "I want to get in!" "Show you got money first!" "Here." "I'll slap you!" "Needn't these ones prove their identity?" "Do your duty!" "Did you hear?" "Even God is angry." "Slivnicky is coming!" "Here it is!" "The auction is cancelled!" "The bank representative can confirm it." "The auction is postponed." "Our bank has given us..." "credit for half a year." "My God, where is the man?" "Stones are falling down!" "That's the end of our crops and hopes." "St. Urban, vine-growers' patron, I pray to you!" "Stop it!" " Our Fathercare about you very much!" "He will turn your head, scoundrel!" "No, he is very shy!" "So why did he run after you?" "It's Easter!" "I don't want to see you with him again!" "Their family brings us bad luck." "Your mother died because of..." "What's wrong with you?" "Send her away!" "You want to marry her, and what about me?" "You will have a baby but I shall never call her a mother!" "Will you stop?" "My mummy was good." "She saved Mark's mummy's life." "Mark's mummy is also good." "She calls me:" "My little bird!" "Where have you been?" "Who will work instead of you?" "I saw the mayor to the town." "What a mayor!" "He is making up the devil knows what." "He should be


here!" "He wants to build a road." "We have not finished one stuff yet!" "I don't care about such societies!" "He also wants electric power in the village." "He will wear us out!" "Electricity is a good thing." "Without me!" "I don't work!" "We work like slaves for nothing." "When we divided the lands, you were not against it." "The legionnaires got more, and now they want to give orders!" "Did I get more?" "Or Babinsky?" "And you forgot that Urban took no land, he wanted us to get more." "I'm not working until after the elections..." "I'll see then." " Is that what he said?" " Yes." "So there will be no road, no power." "We shall live in mud and darkness!" "So what, if we arelike?" "I know you love each other." "She will fight for her love." "She is like her father." "She resembles him." "I hope she has a kind heart like her mother." "The Legionnaire's!" "What a thief!" "Urban saw it coming but you mocked him!" "I was not allowed to leave." "They won't let me see you again!" "Go home then!" "They can see you and punish you!" "Coming from work?" "What happened?" "I don't know if I should kill somebody or hang myself." "Where are you going?" "I'll tell you later, I can't go home now." "Mummy would die if she knew." "Good afternoon." "Is he in?" " Yes, he is." " Will you give me some water?" "What happened?" "The co-op storehouse ended badly." "And me too."


a penny!" "Nothing!" "Let her... drink the nettle tea!" "Three with one letter?" "Will you not read it?" "I know what's in it." "Will you have some?" "If there is any left..." "Don't drink so much, that won't help you." "And what about you?" "You should do something." "Thank you for the advice." "Someone else in your shoes would've had made it long ago!" "Drink!" "Do you remember the day when we welcomed you?" "I must tell you..." "It was almost twenty years ago." "And we have achieved nothing!" "We'll leave but shame behind us." "Without you, this hole wouldn't have progressed." "There is public auction at our place, I need money!" "You shouldn't have gone away." "God is punishing you." "I only want what's mine by the"Next, please!" "Too little!" "We were promised one crown more!" "They deceived us again!" "The householder is not at home." "If he promised, he has to keep his word." "I myself will tell him." "They are mistreating us!" "You are honest, you don't even have decent trousers." "Let her open the safe!" "That would be the worst thing to do." "Dear name, beginning with the letter L..." "Louise?" "We have already made a decision." "We will go on a strike." "What would you do?" "I would go on a strike." "That is what we wanted to hear." "But you must do it reasonably." "How to strike reasonably?" "Make them negotiate while you also take care of the cattle." "I've been calling the police since the morning." "Hello!" "The


When we hear the term ‘Sorting,’ the algorithms which come to our mind are quicksort, insertion sort, merge sort, bubble sort, heap sort, and other sorting algorithms. We would have used the method sort() to sort elements in an array, in our day to day programming tasks. However, have you ever wondered what algorithm does the method uses to sort the items in Swift? Before Swift 5, it was ‘Introsort,’ but after Swift 5, it is ‘Timsort.’ Timsort is a sorting algorithm, used in programming languages like Python, and Java. I am going to cover mostly about ‘Timsort’ in this article.

What is ‘Timsort?’

Timsort is a hybrid sorting algorithm similar to introsort. Hybrid sorting algorithms are the ones which combine two or more sorting techniques to achieve the requiredthe sorted arrays using merge sort. Isn’t it cool? This technique is efficient when compared to introsort. Timsort has a worst case of O(n log n), and non-constant space complexity.

How does Timsort use insertion sort?

Timsort scans the array at first and performs a progressive sorting and merging of sub-arrays(sub-partitions), instead of dividing the entire array at first and merging them at the end. These partitions are known as “runs.” Whenever a run is found, it is added to a stack containing all other previous runs.

My friend, Bruno Rocha tells that, Timsort takes advantage of the fact that in every array of elements, there are contiguous subsequences of already sorted elements. In such cases, Timsort keeps on advancing its pointer until the current sequence stops being an ascending or


equality collisions. Benchmarking script and results can be seen in this gist: https://gist.github.com/natecook1000/5161e10aeba09408c130284ea6ec4e11”

The pull request went through many iterations, and finally, the Timsort pull request was merged in November 2018.

My thoughts about Swift

It is fantastic to see how Swift is evolving every moment. A lot has changed since Swift’s initial release, and it is still changing. This kind of rapid evolution wouldn’t have been possible without the contribution of our Swift community. I realized that the more I learned, the more I understand that I know a very little. (Here is my tweet about it.)

Enjoyed reading it? Feel free to share your comments below. Like this article? Share it with your friends! You can also follow me on twitter right here: https://twitter.com/rizwanasifahmed

References:

If you want to learn more about"CMD 0x%x: failed!\n", command);
		return -EIO;
	}

	do {
		int val = sc6000_read(vport);

		if (val < 0)
			break;

		data[len++] = val;

	} while (len < data_len);

	/*
	 * If no more data available, return to the caller, no error if len>0.
	 * We have no other way to know when the string is finished.
	 */
	return len ? len : -EIO;
}

static int sc6000_dsp_reset(char __iomem *vport)
{
	iowrite8(1, vport + DSP_RESET);
	udelay(10);
	iowrite8(0, vport + DSP_RESET);
	udelay(20);
	if (sc6000_read(vport) == 0xaa)
		return 0;
	return -ENODEV;
}

/* detection and initialization */
static int sc6000_hw_cfg_write(char __iomem *vport, const int *cfg)
{
	if (sc6000_write(vport, COMMAND_6C) < 0) {
		snd_printk(KERN_WARNING "CMD 0x%x: failed!\n", COMMAND_6C);
		return -EIO;
	}
	if (sc6000_write(vport, COMMAND_5C) < 0) {
		snd_printk(KERN_ERR "CMD 0x%x: failed!\n", COMMAND_5C);
		return -EIO;
	}
	if (sc6000_write(vport, cfg[0]) < 0) {
		snd_printk(KERN_ERR "DATA 0x%x: failed!\n", cfg[0]);
		return -EIO;
	}
	if (sc6000_write(vport, cfg[1]) < 0) {
		snd_printk(KERN_ERR "DATA 0x%x: failed!\n", cfg[1]);
		return -EIO;
	}
	if (sc6000_write(vport, COMMAND_C5) < 0) {
		snd_printk(KERN_ERR "CMD 0x%x: failed!\n", COMMAND_C5);
		return -EIO;
	}

	return 0;
}

static


of atherogenic index in diabetic rats. In addition, the chronic administration of mangiferin (10 and 20 mg/kg, i.p.) for 14 days significantly as well as markedly improved oral glucose tolerance in glucose-loaded normal rats suggesting its potent antihyperglycemic activity. The accumulating evidences suggest that both pancreatic and extrapancreatic mechanisms might be involved in its antidiabetic or antihyperglycemic action. In conclusion, the present study demonstrates that mangiferin possesses significant antidiabetic, antihyperlipidemic and antiatherogenic properties thus suggesting its beneficial effect in the treatment of diabetes mellitus associated with hyperlipidemia and related cardiovascular complications.of idolatry. But if we gradually descend from the age of the Antonines to that of Theodosius, we shall learn from a chain of contemporary witnesses that the royal palace and the temple of Serapis no longer contained the four or the seven, hundred thousand volumes which had been assembled by the curiosity and magnificence of the Ptolemies.”

History of the Conflict between Religion and Science, by John William Draper. D. Appleton and Company, 1925 Edition. Pages 103-104: “But it must not be supposed that the books which John the Labor-lover coveted were those which constituted the great library of the Ptolemies, and that of Eumenes, King of Pergamus. Nearly a thousand years had elapsed since Philadelphus began his collection. Julius Caesar had burnt more than half; the Patriarchs


among different BTV serotypes (26 serotypes). Each segment has a 5′ and 3′ untranslated region (UTR) flanking the ORF of the protein(s) that each encodes. The 5′ UTR consists of a conserved pentanucleotide GUUAA and a non-conserved region of variable length ranging from 3 (S4) to 34 nt (S5). The 3′ UTR also consists of a conserved pentanucleotide CUUAC at the 3′ end and a region of variable length ranging from 24 (S1) to 113 nt (S10). Whilst some segments share the same 5′ UTR length, the lengths of the 3′ UTR are unique. Nevertheless, the exact length of the 3′ UTR of BTV segments is conserved between different serotypes, suggesting a strong constraint on this non-coding region. Interestingly, S6 (encoding VP5) and S2 (encoding VP2), which arestructure might serve as a conformational packaging signal for other ssRNA segments of different BTV serotypes.

![Relevance of the RNA secondary structure for packaging of S8 of BTV-1 analysed by the CFA assay. (a) S8 of BTV-1 3′ terminal sequence (69 nt). Nucleotides predicted to be important for the secondary structure are indicated in bold and the mutated nucleotides are boxed. The STOP codon is underlined. (b) Predicted RNA structures of mutant (S8.1 and S8.2) or WT (B1S8) ssRNA segments. The region targeted in each mutant segment is indicated in grey. (c) Packaging was analysed by reverse transcription PCR (fragment of 627 bp indicated by white arrows) of mutant (S8.1 and S8.2) and WT ssRNA. S8 of BTV-1 (+ve) or no ssRNA (--ve) as positive or negative reverse transcription


To the best of our knowledge, however, our study is the first to present experimental evidence for a structural motif being involved in segment packaging. Moreover, we also demonstrated that a similar structural motif exists for a different RNA segment of another serotype (S8 of BTV-1) and that it is functionally important.

The CFA packaging assay employed in this work relies on the interaction of structural proteins with the viral RNA. Participation of cellular factors is unlikely as a plant-based extract was used for *in vitro* translation, but cannot be ruled out entirely. The *in vivo* packaging assay is based on assembly of viral cores within infected cells transfected previously with a mutated segment. The modified segment competes directly for sorting and packaging with the WT segment in theconfirmed the hepatocyte-specific nature of miRNA122a and established its downregulation in HCC cell lines providing a rationale for exploiting the binding site for targeted gene delivery.

![miRNA122a is downregulated in HCC and other cancer cell lines\
In order to quantify the expression levels of miRNA122a in hepatocytes and HCC cells, we isolated total RNA from primary human hepatocytes, HepaRG cells and HCC cell lines. qRT-PCR was then performed to determine the number of copies of miRNA122a which was reported as copy number per 1000 copies of control using the formula (2\^(Ct control--Ct miRNA122a))\*1000. Two-tailed *t*-test was performed between miRNA positive cells: HepaRG, HUCS10P, and HuH7 and miRNA negative HCC cells individually using Graph pad prism 7.0 (*n* \> 3, ^\*^ \< 0.05, ^\*\*\*^ \< 0.005).](oncotarget-09-23577-g001){#F1}

Inclusion of miRNA122a binding sites at


not alter the luciferase expression in the low/non-expressing HCC cell lines (data not shown).

![Inhibition of miRNA122a in hepatocytes rescues the expression of transgene with miRNA122a binding site at the 3′-UTR, whereas overexpression of miRNA122a in HCC cell lines inhibits it\
(**A**) In order to study the effect of inhibition of miRNA122a in hepatocytes on the expression of transgene with miRNA122a binding sites, we co-transfected human hepatocytes (i) and HepaRG (ii) with CMV-GLuc-miR122a\*3 and miRNA122a inhibitor, and CMV-GLuc and miR122a inhibitor and quantified the amount of luciferase secreted. The expression of luciferase was quantified for each group and expressed as a percentage of CMV-GLuc. (**B**) Similarly, HCC cell lines Hep3B, PLC/PRF/5, SKHep1, and SNU423 were co-transfected with CMV-GLuc-miR122a\*3 and miRNA122a mimic, and CMV-GLuc and miRNA122a mimic; secreted GLuc was quantifiedfor each group and reported as a percentage of CMV-GLuc. Two-tailed *t*-test was performed to determine the statistical significance of the observed differences between groups. (*n* \> 3, ^\*\*\*^*p* \< 0.001, ^\*\*^*p* \< 0.005).](oncotarget-09-23577-g003){#F3}

Using a miRNA122a mimic to increase the presence of miRNA in the HCC cell lines, we showed a significant decrease in luciferase expression following transfection with CMV-GLuc-122a\*3 (*p* \< 0.005). Luciferase expression decreased from 89.8% to 27.3%, 75% to 1.8%, 70% to 1.7%, and 101% to 12% (*p* \< 0.005) in HCC cell lines Hep3B, PLC/PRF/5, SKHep1 and SNU423 respectively (Figure [3B](#F3){ref-type="fig"}). The addition of miRNA122a mimic did not alter the luciferase expression in the primary human hepatocytes (data not shown). Taken together, these results confirmed that the observed decrease in reporter expression in miRNA122a


post-transcriptionally targeted gene therapeutic approach for hepatocellular CSCs.

DISCUSSION {#s3}
==========

Rationally designed targeted gene therapy is an attractive therapeutic approach for diseases like HCC which requires a tumor specific action in order to prevent significant off-target effects in an already compromised liver. One of the different strategies for targeted gene delivery is the modification of the therapeutic payload (therapeutic gene cassette) by including disease specific regulatory elements like tumor specific promoters and miRNA binding sites \[[@R22], [@R23]\]. In recent years, there has been accumulating evidence demonstrating the efficacy of utilizing binding sites of miRNAs downregulated in cancers as an effective approach \[[@R24]--[@R27]\]. Given that miRNAs play a pivotal role in virtually every cellular pathway, it is conceivable that they are involved in the development and maintenance of cancer stem cells,the return of miRNA122a to the CSC population inhibits their stemness \[[@R17]\]. Given the importance of miRNA122a in the maintenance, development and initiation of HCC, its liver specificity, and differences in expression levels of miRNA122a in HCC and CSCs, we concluded that there is a strong rationale to explore the efficacy of miRNA122a for post-transcriptional targeting of HCC.

Exploiting the differential expression of miRNA122a between functional hepatocytes, HCC and hepatocellular CSCs, we designed vectors incorporating 3 copies of the binding site of miRNA122a with the goal of limiting expression of transgenes to those cells with reduced miRNA122a expression, i.e. HCC and hepatocellular CSCs. Using luciferase as a marker transgene, we showed that cells expressing miRNA122a (primary hepatocytes and HuH7) had a significant decrease in luciferase expression. Conversely, HCC cells


CSCs \[[@R40]\]. Given that CSCs drive tumor progression and maintenance, their removal can result in tumor degeneration and possibly reduced recurrence \[[@R9]\]. The potential benefits of bystander effects inherent with the CD/5-FC system was seen in our 3D sphere cultures, representing a solid tumor mass, where increased tumor killing was evident.

The increasing knowledge of the genetic makeup of HCC and the CSCs derived from them allows identification of specific expression patterns which make them different from the normal liver cells. Initial work on utilising this knowledge for targeted gene therapy centred on the use of HCC restricted tumour specific promoters, such as that for alpha- fetoprotein (AFP), to drive transgene expression \[[@R41]\]. The use of this type of transcriptional targeting has, however, failed to progress to clinical trials.and SNU423 were co-transfected with miRNA122a mimic (4464066, Life Technologies) (5 pmol) and either CMV-GLuc or CMV-GLuc-miR122\*3. The amount of secreted GLuc for each group was reported as a percentage of CMV-GLuc.

Cell proliferation assay {#s4_7}
------------------------

For cell proliferation assays, 10,000 cells were transfected with CMV-CD or CMV-CD-122a\*3 in a 96 well plate and media containing 10 μm 5-FC was added after 24 hours. CellTiter96 Aqueous One Solution Cell Proliferation Assay kit (Promega Corporation, Madison, WI USA) was used to quantify cell proliferation after 48 hours of incubation with 5-FC containing media. Absorbance was measured at 540 nm with the Infinite 200 Pro NanoQuant. Percentage proliferation was calculated for CMV-CD and CMV-CD-122a\*3 for each cell line and percentage proliferation with CMV-CD-122a\*3 was reported relative to CMV-CD in order to account


for the difference in transfection efficiencies across cell lines.

Cell death assay with Annexin V/PI {#s4_8}
----------------------------------

To quantify cell apoptosis, flow cytometry based on Annexin/PI staining was used (Life Technologies). 30,000 cells were transfected with CMV-CD and CMV-CD-122a\*3 in a 24 well plate and incubated for either 24 hours (for tumorspheres) or 48 hours (adherent cells) with 10 μm 5-FC containing media. Cells were then washed with PBS, collected and co-stained with Annexin V and PI as recommended by the manufacturer. Annexin V/PI positive cells were quantified with the FACS Canto II and data analysis was performed with FCS express 3. The percentage of apoptotic cells after transfection with CMV-CD-122a\*3 was normalized with CMV-CD.

Statistical analysis {#s4_9}
--------------------

All experiments were repeated at least thrice in triplicates and results were presented as meansite by using an adhesive.
As the electromagnetic shielding member serving as the wave reflector, the following structures are generally used: a structure in which thin iron sheets each having a thickness of 1 mm or less are plated, and the iron sheets are joined by soldering, a structure in which iron sheets each having a thickness of 1 mm or more are used, and the iron sheets are welded and are shield-joined, and a structure in which panels are formed by iron plates and shield-joined by metal fasteners.
When the anechoic chamber is constructed by using the multilayered wave absorber as described above, there are problems which are described below.
Even if a highly reliable adhesive is used in attaching the dielectric material, there is a possibility that an exfoliation


I decided to answer truthfully. It was worse than any other pain I ever had at which point her eyes appeared to bulge out and she croaked out "worse than labour?" Wherein I quickly found out that this first time mom had been worried about her bellybutton popping out and whether the popping would take a long time and how much it would hurt. I quickly assured her that she wouldn't feel a thing, stopping myself just in time before I stated that she had other pain to worry about and then feeling somewhat pleased with myself that at least I had stopped myself being an even greater fool. This somewhat allayed her fears until she asked me, "wait, how much did you say labour hurt?"

It's not calledindependently without major-label distribution, particularly after they severed their ties with Atlantic Records the year before.

Track listing
"Do You Hear the Lambs Calling"- 2:10
"Work It Out"- 3:07
"We're Fuckin'"- :42
"Bad Land Boogie"- 3:54 *feat. Home Team
"I Got a Fuckin' Headache"- :31
"Tell Me What You Know"- 6:04
"Dre's Momma Needs a Haircut"- 1:03 (Diss track aimed at Dr. Dre, Snoop Dogg and Death Row Records)
"Cowards in Compton"- 3:59 *feat. JT Money & Clayvoisie (Diss track aimed at Dr. Dre, Snoop Dogg and Death Row Records)
"Head, Head & More Head, Pt. II"- 4:30 *feat. JT Money & Jiggie Gee
"Weenie Roast"- :39
"Menege a Trois, Pt. II"- 5:06
"Pimple on My Dick"- :50
"The Hero"- 3:19


the spectra are corrected from telluric features, we separated in-transit spectra from out-transit spectra. An in-transit spectrum, $f(\lambda,t_\mathrm{in})$, is a spectrum obtained when the planet occults a part of the stellar disk, while an out-transit spectrum, $f(\lambda,t_\mathrm{out})$, corresponds to the full-disk stellar spectrum.

-   We corrected each spectrum for the stellar reflex motion induced by the planet, using the orbital parameters in Table \[paramètres utilisées\].

-   Then, we created the normalized master out-transit spectrum which is the sum of the out-transit spectra: $$\begin{aligned}
    \tilde{F}_{\mathrm{out}}(\lambda)=\sum f(\lambda,t_\mathrm{out})
    \label{master out}\end{aligned}$$

-   We normalized all the in-transit spectra to the continuum level of the master out-transit spectrum with a fourth-degree polynomial. This normalization was made from 5338Å to 6900Å, which corresponds to the red     101
  Fitted Gaussian contrast \[ppm\]      59$\pm$17   68$\pm$23
  Theoretical contrast \[ppm\]             37          46
  ------------------------------------ ----------- -----------

  : Main characteristics of the observed and theoretical CCFs at 1700 and 2100K.[]{data-label="recap résultat"}

\
To further test our detection limit estimates, we injected the model of Fig. \[TS theory 2100\] scaled to an average amplitude of 100 ppm. The injection was done in the in-transit spectra before the telluric correction. We applied the same data reduction procedures as above. The Gaussian fit on the resulting CCF is shown in Fig. \[CCF eau 2100K planet base injection\]. The


is encouraging. But I am afraid it is reversible. In any case, I
wish them good luck.

------
jerryji
Let me tell you how --

From the top: government blessing, (biased) censorship

From the bottom: much more native friendly domain name, thirst of pirated
music, nationalism, ignorance

From the corporate itself: ferocious marketing and sales -- not everyone
realizes that THE most effective way of doing business in China is to hire as
many marketing and sales people as the number of the bullets Arnold
Schwarzenegger shoots, and I can assure you that it'll be much more effective
than his shooting/acting.

------
jusob
Baidu was indeed helped by the Chinese government. For example, google.com was
redirecting to baidu.com ([http://www.therawfeed.com/2007/10/chinese-
redirecting-google...](http://www.therawfeed.com/2007/10/chinese-redirecting-
google-yahoo.html) for example), Baidu can (could?) also help looking for
illegal mp3
([http://www.danwei.org/china_information/baidu_bidu_guide_bai...](http://www.danwei.org/china_information/baidu_bidu_guide_baidu_ipo_bai.php)),
etc.

------
haseman
How to outsmart Google? Easy in just a few steps:

First, overthrow whatever governmental system is currentlyI am thrilled to participate in the blog tour for this special book. I had the opportunity to send questions to Mr. Alonso for a Q & A. If you are looking for a unique addition to the dinosaur collection in your library or classroom to inspire either budding young paleontologists or artists, look no further.

Hop on over to Proseandkahn for the interview (my first), my review and links to the next stop on the tour, the book trailer and a giveaway!


of the nitrogenase reductase gene nifH, a marker of biological nitrogen fixation, was determined in only two strains of A. nitroguajacolicus A18 and A34. None of the tested strains released compounds inhibiting in vitro the growth of the fungi Fusarium moniliforme and F. graminearum, pathogenic to maize. Seed inoculations with the A. nicotinovorans strain A7 suppressed the development of seedlings of four maize cultivars, which were not colonized by this species of bacteria, but stimulated the development of seedlings of the host-cultivar Król. Also, the A. nitroguajacolicus strain A18, which was applied as seed treatment, suppressed the development of seedlings of three maize cultivars, which were not colonized by this species of bacteria. The occurrence of endophytic A. nicotinovorans and A. nitroguajacolicus inhabiting interior tissues of maize leavesconventional spectacle arrangement wherein the frames are formed with "U" shaped cavities to enable positioning of reflective material therein. While being an effective means of accepting ornamental material within a framework structure in spectacles, the Anger patent fails to provide any means for electronically controlling a predetermined pattern of lights within the frames.
U.S. Pat. No. 3,526,450 to Berry presents an ornamental spectacle covering for conventional eye glasses where an elastic envelope about the associated framework is provided for supporting various ornamental and decorative indicia and characters upon the envelope.
U.S. Pat. No. 2,682,724 to Pattillo sets forth a spectacle frame arrangement wherein the spectacles accommodate a series of reflective brilliants for ornamental and fashion purposes.
U.S. Pat. No. 1,555,388 to Schumacher presents a spectacle frame arrangement for supporting a series


   return item.wrapper && item.wrapper.element ? React.createElement(item.wrapper.element, item.wrapper.attributes, item.name) : item.name;
  };

  // nav list divider

  AppSidebarNav2.prototype.navDivider = function navDivider(divider, key) {
    var classes = classNames('divider', divider.class, divider.className);
    return React.createElement('li', { key: key, className: classes });
  };

  // nav label with nav link

  AppSidebarNav2.prototype.navLabel = function navLabel(item, key) {
    var classes = {
      item: classNames('hidden-cn', item.class),
      link: classNames('nav-label', item.class ? item.class : ''),
      icon: classNames('nav-icon', !item.icon ? 'fa fa-circle' : item.icon, item.label.variant ? 'text-' + item.label.variant : '', item.label.class ? item.label.class : '')
    };
    return this.navLink(item, key, classes);
  };

 // nav dropdown

  AppSidebarNav2.prototype.navDropdown = function navDropdown(item, key) {
    var classIcon = classNames('nav-icon', item.icon);
    var attributes = this.getAttribs(item.attributes);
    var classes = classNames('nav-link', 'nav-dropdown-toggle', item.class, attributes.class, attributes.className);
    delete attributes.class;
    delete attributes.className;
    var itemAttr = this.getAttribs(item.itemAttr);
    var liClasses = classNames(this.activeRoute(item.url, this.props), itemAttr.class, itemAttr.className);
    delete itemAttr.class;
    delete itemAttr.className;
    return React.createElement(
      'li',
      _extends({ key: key, className: liClasses }, itemAttr),
      React.createElement(
        'a',
        _extends({ className: classes, href: '#', onClick: this.handleClick }, attributes),


[19921: Laecca v. New York Univ.. 7 A.D.3d 415: Fernandez v. 707. Inc.. 85 A.D.3d 539 [1st Dept. 2011]; Paez v. 1610 Nicholas Avenue. L.P.. 103 A.D.3d 553 [1st Dept. 2013]).

In the case at bar, the area wherein the accident occurred was not within the areas contemplated by Section §7-210 of the New York City Administrative Code, as being the responsibility of a land owner. Moreover, YG hired Cypress to specifically install/renovate a commercial kitchen and cellar inside its premises, not on the street. Additionally, there is no evidence to indicate that YG somehow exercised control over the work it hired Cypress to perform or that said work was inherently hazardous. Furthermore, and more importantly, the Court has reviewed various documents annexed as exhibits to YG's motion. Theseon with story after story of this stuff, always repeating the same basic routine: child decides to mate with a third-world primitive, family is shocked, appalled, depressed, and eventually resign themselves to their fate.

Some of these stories are more disgusting than others though.

Jake Clark, 24, and Reon Cloete, 28 Where they met: Online. Married in March Jake: I married my gay, Namibian-born husband in a small Minnesota chapel in a largely all-white community this March. The church was covered with German writing, and since my partner’s family didn’t have the notice to attend, the small audience was almost entirely blue-eyed and blond. Our marriage announcement shocked almost everyone in our families, as did our plan to marry within the next couple of weeks.

*Gags* What… Beautiful children… *bleurg* They’ll


legacy, and would instead dedicate his life to masturbating in other men’s anuses. After swallowing that pill, I guess him “marrying” a jungle ape wasn’t that big of a deal.

In any case, none of this would be happening if only we had White sharia. The thots would be kept in line, the homos would be thrown off rooftops, and fathers would have veto power over their daughter’s marriage choices.

But, you know, maybe you prefer keeping things the way they are, and let your Aryan princesses make their own choices or something, lol. Your choice.

Actually, I lied.

You have no choice.scenario almost impossible to implement [@riotto].

In the context of a two-Higgs model and in the absence of extra [*CP*]{} violating terms, domains of the Universe can first tunnel to a new type of minimum in which either of the two Higgs doublets develop no vacuum expectation value, before evolving to the usual electroweak symmetry breaking minimum[^1]. In other words the phase transition occurs in two stages. The first stage has been shown to be a first order transition, while the subsequent is of second order [@zarikas]. Fluctuations of the minimum, which we have due to the presence of the extra terms, are then proved to lead to amplified [*CP*]{} violation at high temperatures [@zarikas] in the same spirit with Ref. [@come; @come2], resulting to reasonably large baryon asymmetry. This


same time $V_{CX}$ becomes unstable and through a second order phase transition the scalar fields roll towards the stable minimum $V_{C}$. The kind of evolution just described occurs for instance when $\beta <0.8$, $\lambda _{6,7}>g^{2}$, $m_{3} \lesssim 100 {\; \mathrm{GeV}}$ but the bound on $m_{3}$ can be relaxed if the parameter $\beta $ is very small. However this is not the only parameter region where this interesting subcase is realized.

2.  There are also values in the parameter space for which, after the symmetric vacuum, the charge preserving minimum $V_{C}$ is developed. At a later stage of the evolution, a charge violating saddle point $V_{CX}$ starts forming which stays higher than $V_{C}$ during the whole evolution. Then the final stage of the evolution in this case does notgravitational density perturbations. Thus, charge asymmetries induce temperature fluctuations in the microwave background (Sachs-Wolfe effect). In this case the constraint is: $n_{Q}/s\leq 10^{-29}$. Any specific two-Higgs doublet model which does not respect the aforementioned bounds has to be excluded on cosmological grounds.

Now we will shall see that within the context of the SM, no net charge asymmetry can be produced, even if the Universe passes from a charge violating phase. However the case is very different in the presence of heavy leptons.

As we have already discussed the phase transition happens in two stages. The $U(1)_{em}$ gauge symmetry can be broken during the first one. One can realize the violation of the $U(1)_{em}$ gauge symmetry because of the development of non-vanishing vev’s in the charged components of the Higgs


-h_{e}\bar{\nu}_{L}e_{R}\langle \phi
_{1}^{+}\rangle \,+\,h.c.  \label{yuk}\end{aligned}$$ The first three terms yield the usual mass terms for the fermions, while the rest lead to a mixing between fermions of different electric charge. There are no additional interactions in the Yukawa sector, except those appearing in Eq. (\[yuk\]).

In the following for definiteness we shall elaborate the $\beta <1$ case. Analogous results can be obtained for the $\beta >1$ case. From Eq. (\[yuk\]) it is seen that only $d$ and $u$ quarks suffer a mixing. The mixing between $e$ and $\nu $ is absent, since $\langle \phi _{1}^{+,0}\rangle=0$. In this case the gauge and mass eigenstates of leptons are the same.

As far as the potential is concerned there are new mass terms and interactions, that mix charge and neutral components of Higgs doublets. Theseof the specific form of the effective potential.

[^5]: However this does not guarantee bubble formation with kink-like walls [@goldenfeld].

[^6]: The case $\beta >1$ is identical to $\beta <1$ with the interchange $\Phi_{1} \rightleftharpoons \Phi _{2}$.

[^7]: The $W^{\pm}$ are the usual linear combinations ${\frac{1 }{{\sqrt{2}}}}(W^{(1)}\mp iW^{(2)})$. During the charge breaking stage the $\pm$ labels do not correspond to any physical electric charge assignment.


Detailed analysis of a series of explanted Talent AAA stent-grafts: biofunctionality assessment.
Six Talent stent-grafts were harvested at reoperations (N=5) and autopsy (N=1). The explants were observed nondestructively, including gross morphology, X-rays, CT scans and closed pressure system analysis. The Nitinol frames in three devices harvested at reoperations and another harvested at autopsy were intact. One had a stent fracture of the proximal bare stent, and one had a wire fracture of a thin proximal external supporting stent as well as a hole in the fabric just above the bifurcation. For the three devices structurally intact, reoperations were performed for a type 1A endoleak (one patient) and aorto-enteric fistulas (two patients). The healing characteristics were poor or absent. The fabric in the main body of the grafts harvested afterstuff i left the other day.. and passed out on his couch for a few hours. This cold is taking a toll on me.. making me tired every second! Now i'm home and playing around with the camera. At least today was a decent day.

Oh yeah.. i was supposed to meet Fujike today @ David's party but i was way too tired and sick to go. Sorrry Nance.

Haven't blogged in a while.. nothing else good has happened so nothing to really write about. My life just keeps slumping more and more to the floor. Where did ALL this bad karma come from? And it's hitting me one at a time.. like someone said, "using the chinese water torture technique" which is dropping a single drop of water in


Furious. The White House intimidated CBS into not permitting Attkisson to do interviews about Fast and Furious. An Orlando Sentinel reporter was kept locked in a closet until after Joe Biden had concluded speaking at a fundraiser.

The White House denied they had threatened to remove Carla Marinucci and possibly other Hearst reporters from the press pool covering Obama in the Bay Area in April 2011 and then lied about it. CBS News reporter is also on record protesting the limited press access to Obama fundraisers. The Obama truth team (an specious oxymoron if ever there was one) ordered ISP GoDaddy to shut down the political website of private investigator Douglas Hagmann, because it supposedly contained information that was “maliciously harmful to individuals in the government” (read: it exposedsizeof(buffer), thus getting essentially no writable space. Upon fiddling with declarations and ending up at this, I obtained the IP and port correctly with the cmsg loop. I still don't know why TPROXY warps the packets when viewing them through a raw socket, which would be interesting to know.
iov.iov_base = cPacket;
iov.iov_len  = BUFSIZE;

mHeader.msg_name       = &sSourceAddr; //sockaddr_storage
mHeader.msg_namelen    = sizeof(struct sockaddr_in);
mHeader.msg_iov        = &iov;
mHeader.msg_iovlen     = 1;
mHeader.msg_control    = cControl;
mHeader.msg_controllen = BUFSIZE;

for (cmsghdr *cmsg = CMSG_FIRSTHDR(&mHeader); cmsg != NULL; cmsg = CMSG_NXTHDR(&mHeader, cmsg))
{
    if (cmsg->cmsg_level != SOL_IP || cmsg->cmsg_type != IP_ORIGDSTADDR) continue;
    std::memcpy(&sDestIP, CMSG_DATA(cmsg), sizeof(sockaddr_in));
    iPort = ntohs(sDestIP.sin_port);


diarrhea for 2 months bad muscle cramps pain, knots, etc... and weakness. I have heard there can be false negatives? so I did go gluten-free and saw improvement.In December I requested a genetic test. and it came back positive with low risk. I didn't realize after that that she added "celiac sprue" as an ongoing health condition in my file until I saw a dietitian a couple weeks ago and she asked me when i was diagnosed celiac. Confusing right?

When I spoke with my doctor the other day it was still confusing (she doesn't seem to understand my questions I guess- or i don't understand her accent)

She repeated the gene test results. I asked if I am to assume that means I have celiac and she said yes.it around the 18th- Century. The first cards to be mass-produced in the US were created by Esther Howland in 1840. This earned her the moniker Mother of the Valentine. She should be called the Mother of Hallmark.

How We Celebrate Today

The Greeting Card Association estimates that 1 billion cards are sent annually. Hallmark claims that 50% of its V-Day cards are bought in the 6 days preceding Feb 14th. 180 million roses were purchased for Valentine's Day in 2005 and accounted for 34% of the annual sales dollars. $2.4 billion was spent on jewelry in February 2005, presumably largely for Valentine's Day. And sadly 15% of flowers are self-sent.

Best: Sleepless in Seattle

Worst: Fifty Shades of Grey

The movie might help to get you guys in the mood, but you


Q:

No compilation error comparing integer with string?

Probably like many, I typed this typo
int a = 0;
cout << a < " "; //note the '<'

However, the MSVC++ compiler threw just a warning

warning C4552: '<' : operator has no effect; expected operator with
  side-effect

though I expected a compilation error. Is it indeed standard complaint code? Does any implicit type conversion or overloading happen which make the code valid? I am also confused whether < operator is comparing the string " " with an integer a or with the result of cout << a
A related SO post is here.

A:

The << operator has a higher precedence than <, so this is parsed as
(cout << a) < " ";

You are not really comparing a string with an integer. Instead, you arepeople do. They get to frolic and run around with their friends. They explore the dog park and get to flirt a little with the others, as well. It’s also a great chance for you to get to hang with some like-minded people and share fun stories about what your dog has been up to lately.

9. You Only Hire the Most Qualified Sitters When Out of Town

Okay, so maybe your nephew isn’t the top choice, but you want someone who will actively play and engage with your pooch while you’re out of town. Knowing they are well taken care of and loved is an important factor if you can’t be there. Plus, it’s one less thing to worry about during that business trip. You’ll nail it knowing your


buddy is being looked after properly.

10. You Have Both Dog Treats and Human Treats on Your Counter

Guests see treats on your counter and go to reach for one…the wrong one. You’ve gotten so good at making dog treats for your buddy that they are starting to look like things your friends can eat. No matter how many times you’ve warned your friends, they still reach for the treats without thinking. (My grandfather made the mistake once, we still have a chuckle about it today.)

11. You Constantly Trip Over Toys

Balls, squeaky toys, ropes, and stuffed animals are everywhere. On the couch, next to it, under it, on the stairs, in your bed. The list goes on. Your pooch has so many toys, it’s starting to look like a toddler’swhether or not to even wear a jacket over my three layers of shirts, then a cold breeze hit me and I knew the jacket was going on. Within a few minutes, I was walking down a long trail toward an area where I’d seen a lot of deer activity last year. My dad and a friend were already there from camping out the night before, and we’d agreed earlier on where everyone was going so we wouldn’t cross paths and mess up each other’s hunt.

After about twenty minutes of still hunting, a young spike buck emerged from a clearing and presented a nice broadside shot for me, but unfortunately it is illegal to shoot any buck of less than four points in the state of Mississippi. I


[Percutaneous silicone catheters in the newborn infant].
246 percutaneous insertions of silastic venous catheters were performed in 189 newborn infants. This technique makes perfusion in newborn easier and safer, with less complication risks and less work for nurses. Furthermore silastic venous catheters insure a better observation of neonatological care methods. As a consequence it improves the vital prognosis and the quality of newborn survival in the newborn intensive care unit.To date, more than 180 different germline *CDH1* mutations have been identified in HDGC families in a diverse range of ethnic groups. Mutation carriers have a cumulative risk of GC at 80 years of 70 % for men and 56 % in women, together with a high probability of lobular breast cancer in females (Corso et al. [@CR6]; Hallowell et al. [@CR10]; Hansford et al. [@CR11]). Germline *CDH1* mutations have been identified in approximately 15--50 % of affected kindreds that meet the clinical criteria for HDGC. The wide range of this estimate has to do with both, the background incidence of gastric cancer and the criteria used to define the syndrome. According to the new guidelines, defined in 2015, *CDH1* testing should be considered in patients who meet one of the following


at the age of informed consent (16 or 18 years of age depending on the geographic place of residence) (Blair et al. [@CR2]; van der Post et al. [@CR19]). However, decisions as to the age at which to institute testing should also take into account the earliest age of cancer onset in the individual family.

PTG is now strongly recommended for asymptomatic *CDH1* mutation carriers. Total gastrectomy for these patients completely eliminates their risk of GC and is truly prophylactic in terms of preventing their death from invasive GC. The current consensus is that the procedure should be discussed and offered to pathogenic *CDH1* carriers in early adulthood, generally between ages 20 and 30 and should be carefully considered at an age \>75. Family phenotype, especially age of onset ofclinical cancer in probands, should be taken into account. Some suggest consideration of total gastrectomy in *CDH1* mutation carriers at an age 5 years younger than the youngest family member who developed gastric cancer (Cisco et al. [@CR5]). In *CDH1* positive patients who deny or want to delay the PTG endoscopic surveillance should be considered.

According to recent studies, there is a significant difference between asymptomatic and symptomatic patients who undergo prophylactic total gastrectomy. These studies demonstrated that asymptomatic patients were all cured after the surgery whereas a high percentage of symptomatic ones had tumour recurrence or metastasis, and 60 % of them died within 2 years (Chen et al. [@CR3]; Corso et al. [@CR6]). In addition, data from over 100 gastrectomies for HDGC have high-lighted the majority already contain a tiny


mutations are evenly distributed along the gene and lead to functional haploinsufficiency of E-cadherin. *CDH1* is a tumor suppressor gene, and therefore a somatic second hit is required for initiation of tumor formation. The trigger and molecular mechanism by which the second allele of E-cadherin is inactivated appears to be diverse, and includes promoter hypermethylation, mutation, and loss of heterozygosity. The end result is loss of expression of the cell adhesion molecule E-cadherin.

Currently, there are not reliable methods for early detection, and GC patients have often a poor prognosis since it is often detected at advanced states, more aggressive and difficult to treat, being considered not curable (Black et al. [@CR1]; Garziera et al. [@CR9]; Onitilo et al. [@CR16]). Annual endoscopic surveillance is recommended but direct visualization withset into them and display stands behind, are one of the most familiar elements of in the Pompeian street scene.”

If it was not the standard term, do we know the actual one?

A:

pŏpīna is the one, borrowed from Oscan or Umbrian, and cognate with (native Latin) coquina. Indeed, a Packhum search gives no results for thermopolium and 54 results (59 matches) for popina - note that, still, thermopolium can be found e.g. in Plautus and Petronius.
Note that caupona and taberna were also common, but while L&S lists them as synonyms, they meant something slightly different. The former was more precisely a place where you could also sleep. The latter term, if not qualified with a following adjective (libraria, unguentaria, etc.), indicated a place where only or mostly wine was


highly specific for RA and is predictive of radiological involvement in RA patients. In this study, we found that CCN3 expressions of RA patients were positively correlated with the serum level of anti-CCP antibody and RA disease activity score. Furthermore, a positive correlation between CCN3 and IL-6 was also observed in RA patients. These data suggest that CCN3 may be an inflammatory factor during the process of RA and may serve as a biomarker or an alternative therapeutic target in managing RA.

2. Materials and Methods {#sec2}
========================

2.1. Patients and Control Subjects {#sec2.1}
----------------------------------

A total of 41 RA patients were recruited from the Department of Rheumatology and Clinical Immunology, Jiangxi Provincial People\'s Hospital Affiliated to Nanchang University. The RA patients were all diagnosed complying with the 1987 revised diagnostic criteria ofvalue         0.413   0.418    0.879    0.463   0.604   0.024^∗^   0.011^∗^   0.001^∗∗^   0.198     0.001^∗∗^

Spearman\'s correlation analysis was used to calculate significance. ∗ indicates *p* \< 0.05; ∗∗ indicates *p* \< 0.01.

######

Correlation analysis between DAS28 (CRP) and laboratory variables in RA patients.

  Characteristics   WBC     Lym      Hb      PLT     IgG     IgA        IgM         IL-6        TNF-*α*


for him. Will he give into it? Would that ...…

This week it's another two player game, with Christine and Austin playing Star Crossed! A woman without home or family, other than the rats she loves, meets a man without kindness, except for the dog he loves. In each other they find an unlikely connection, but will fate allow them a happy ending? Star Crossed is by Alex Roberts You can follow ...…

This week it's another two player game with Christine and Austin playing Showdown! Join us as a cultist of a death god and an ambitious warrior struggle in a duel to the death while remembering the long history that lead them to this moment. Showdown is by Seth Ben-Ezra You can follow us on Twitter here, orDual domain watermarking for authentication and compression of cultural heritage images.
This paper proposes an approach for the combined image authentication and compression of color images by making use of a digital watermarking and data hiding framework. The digital watermark is comprised of two components: a soft-authenticator watermark for authentication and tamper assessment of the given image, and a chrominance watermark employed to improve the efficiency of compression. The multipurpose watermark is designed by exploiting the orthogonality of various domains used for authentication, color decomposition and watermark insertion. The approach is implemented as a DCT-DWT dual domain algorithm and is applied for the protection and compression of cultural heritage imagery. Analysis is provided to characterize the behavior of the scheme under ideal conditions. Simulations and comparisons of the proposed


Effects of palmitate on astrocyte amino acid contents.
The effects of palmitate on intracellular and extracellular amino acid concentrations of cultured astrocytes was studied. Exposure of astrocytes to either 0.72 mM or 0.36 mM palmitate was associated with a significant reduction in the intracellular pool of glutamine and taurine. In contrast, the intracellular concentration of histidine, glycine, citrulline, isoleucine and leucine were increased in the presence of 0.72 mM palmitate. Comparable changes in the extracellular amino acid pool were not observed. The data suggest that palmitic acid, which accumulates in the brain during periods of anoxia, alters the metabolism of several amino acids in cultured astrocytes. These changes may be of significance in terms of the pathophysiology of a stress such as anoxia.//
//     Generated by class-dump 3.5 (64 bit).
//
//     class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2015 by Steve Nygard.
//

#import <Foundation/NSLock.h>

@interface NSLock (HealthKit)
- (void)hk_withLock:(CDUnknownBlockType)arg1;
@end


queues = search.get_sobjects()
        queue_id = 0

        for queue in queues:

            queue_id = queue.get_id()

            # attempt to lock this queue
            # have to do this manually
            update = """UPDATE "%s" SET state = 'locked' where id = '%s' and state = 'pending'""" % (table, queue_id)

            sql.do_update(update)
            row_count = sql.get_row_count()

       continue

            self.keep_jobs.append(job)

        self.jobs = self.keep_jobs

    def check_new_job(self, queue_type=None):

        num_jobs = len(self.jobs)
        if num_jobs >= self.max_jobs:
            print("Already at max jobs [%s]" % self.max_jobs)
            return

        self.job = self.get_next_job(queue_type)
        if not self.job:
            return


    # set the process key
        process_key = self.get_process_key()
        self.job.set_value("host", process_key)
        self.job.commit()

        self.jobs.append(self.job)

        # get some info from the job
        command = self.job.get_value("command")
        job_code = self.job.get_value("code")

        try:
            kwargs = self.job.get_json_value("data")
        except:
            try:
       is the highest common divisor of v and s?
8
Let h be ((-60)/45)/((-404)/132 + 3). Calculate the highest common divisor of 473 and h.
11
Let k(p) = -4*p - 129 + p**2 + 63 + 69. Suppose -8 = -s + 4*h, h = -s + 2*h + 5. Let u be k(s). Calculate the greatest common factor of 3 and u.
3
Let x(a) = 9*a - 41. Let o be x(6). Let p(h) = -13*h - 13. Let w be p(-9). What is the greatest common factor of w and o?
13
Let j(y) be the first derivative of y**3 + y**2/2 + 4*y - 12. Let w be j(-2). What is the greatest common divisor of w and 21?
7
Let b be (-31)/((2/6)/(78/(-18))). Calculate the highest common divisor of b and 104.
13
Let


the Cooperation and Verification Mechanism (CVM).

While the CVM reforms are mentioned, and progress in judicial reform and organised crime is expected, leaving the CVM is not a precondition.

As of October 2019, Finance Minister Vladislav Goranov's target was to enter the ERM II by April 2020.

Status
Bulgaria met 3 out of the 5 criteria in the last convergence report published by the European Central Bank in May 2018.

Linguistic issues

The Bulgarian language's use of a Cyrillic script and its not straightforward transliteration of the word euro have caused some issues regarding the official use of the language relating to the euro. The European Central Bank and the European Commission initially insisted that Bulgaria adopt the name ЕУРО (i.e., euro), rather than the original ЕВРО (i.e., evro)  (from BulgarianPV systems. These soiling losses averaged 0.051%/day during dry periods for a sample of 1286 residential and commercial PV sites in California [@mejia2013soiling]. There were significant differences, however, between rates with 26% of sites having losses above 0.1%/day while systems with a tilt angle $<$ 5$^{o}$ had mean soiling losses of 0.18%/day. There were no statistically significant differences observed by region, making such a phenomenon more difficult to model. The effect of ground conditions, and similar particulate matter contributors, coupled with cleaning methods, when employed, introduce difficulties in estimating the soiling losses of aggregate PV sites such as a residential feeder. Issues such as the degradation of PV arrays and effect of cell temperature further impact the reliability of feeder-specific generation estimations.

In this paper, we propose a methodology


a five-minute moving average filter.

![Proxy irradiance measurements obtained from a nearby PV site and the PV generation active power calculated from $\mu$PMU$_2$ measurements.[]{data-label="fig:IrradianceProxy"}](Irradiance_Input.png){width="100.00000%"}

Power Factor Based Estimator
============================

Neglecting losses in the network, for the generic case of a $\mu$PMU measuring the power demand of a feeder, the measured apparent power, $S^{i}_{PMU,t}$, can be expressed as a summation of the apparent power of the load,$S^{i}_{Load,t}$, and the apparent power of installed PV, $S^{i}_{PV,t}$. Equation  represents this for each phase $i$ at time $t$: $$S^{i}_{PMU_1,t}=S^{i}_{Load,t}+S^{i}_{PV,t}
\label{eq:ComplexPower}$$ Expanding on Equation , we formulate Equation : $$\overbrace{
    \begin{bmatrix}
    cos{\Phi^{i}_{Load,t}} & cos{\Phi^{i}_{PV,t}}\\
    sin{\Phi^{i}_{Load,t}} & sin{\Phi^{i}_{PV,t}}
    \end {bmatrix}}^{A}
    \times
     \begin{bmatrix}
    |S^{i}_{Load,t}|\\
   measurements obtained from $\mu$PMU$_2$. Hence, we propose to use the property given in Equation  to estimate the variance of PV. Specifically, we first calculate $Var(\epsilon_{PMU_1})$ during daytime periods. Then, assuming the nighttime $Var(\epsilon_{Load})$ is representative of the daily variance in the load, we calculate the variance in PV. Formally, to estimate $Var(\epsilon_{PV})$, we first obtain $Var(\epsilon_{Total})$ using the following model used in LE: $$P_{PMU_1}=k_{eff} Q^{t}_{PMU_1}+C_{eff} \phi^{t} + R + \epsilon^*_{Total}, \hskip14pt \forall t\text{ where }\phi^t > 0
\label{eq:linear_model_aggregate}$$ We then use the property introduced in Equation  to estimate $Var(\epsilon_{PV})$.

To distribute the errors relative to the *goodness* of each model (i.e., to minimize the variance of the weighted average), we multiply the expected error in the objective function by the inverse of its variance. Hence, we define $\alpha^*$ and $\beta^*$


the straw that broke the camel’s back? There was a recent article by Aideen Sheehan in the Irish Independent, with the headline of “Craft Beers: Why you might just be drinking a lot more than you think…”

Within the article were over-reachingly broad statements such as “If you are a regular drinker of craft beers, you may be over-indulging without realising it.” As a regular consumer of craft beer, I know the ABV and serving size of the beers I am drinking, as it is clearly stated in most cases on the tap, or failing that, on the Tap Board. In the case of high ABV beers, the staff will often tell me. The insinuation that Craft Beer drinkers are blindly necking beer without knowing the strength of thebeer is frankly insulting. Craft Beer drinkers are in general more educated about what they are consuming than Industrial Beer drinkers. Craft Beer Brewers unlike Industrial Beer Inc like to educate their consumers about their beers and what exactly goes into their beers.

The author also fails to realise that for cash flow and excise reasons, a lot of brewers brew beer to approximately 4.5%, In fact, there are several that are under that ABV point such as Bru Brewery “Rua”, Blacks Brewery “The Session”, Bo Bristle “Amber” and other ‘session beers’. It’s extremely disingenuous to imply that all Craft Beer is ‘high ABV loony juice’. For context, a pint of Peroni Nastro Azzuro is 5.1%, Stella Artois is 5.2%, Coors Light 4.3%, Heineken is 4.3% Also. Brewers release


processes of a
radical. In 2006, she wrote a book about mind control called Brainwashing: The Science of Thought Control, which explored the science behind the persuasive tactics of such groups as cults and al Qaeda.

"We all change our beliefs of course," Taylor said in a YouTube video about the book.
"We all persuade each other to do things; we all watch advertising; we
all get educated and experience [religions.] Brainwashing, if you like,
is the extreme end of that; it's the coercive, forceful, psychological
torture type."

Personally, I view raising children in Christian fundamentalist homes to be a form of child abuse since the damage done can affect individuals' lives for their entire lives.Raising children to be full of fear, hate and close mindedness is not a positive thing for society.

The insanity thatLGBT adults is premised on absurd assumptions and stereotypes that perpetuate homophobia and ignorance,” Lara said in a press release.

Karen England, Executive Director of the antigay Capitol Resource Institute, was not happy.

Lara opened his roughly six and a half minute speech on the Senate floor with the Boy Scout pledge and then noted that neither the Girl Scouts, nor the 4-H clubs, nor the Boys & Girls of America nor the YMCA discriminate against gay kids, making them eligible for tax-exemption. The BSA, however, “is an organization with the central flaw so profound that until it is fully fixed, it means that they are out of line with the values of California and should be ineligible for a tax benefit paid for again by all Californians…”

EQCA notes that