key border sites from Nogales, Ariz., in the west to the Rio Grande Valley and to points eastward.

The production will also feature on-the-ground interviews with law enforcement offices in Texas including the City of San Juan Police Department and Cameron County Sheriff’s Office as well as in Arizona with the Cochise County Sheriff’s Office. Experts Lenny DePaul, a retired Chief Inspector with the U.S. Marshal Service, and Dr. Victor M. Manjarrez, Jr., a retired Chief Patrol Agent who served in both Tucson and El Paso Sectors are featured interviews as well.

We spoke with Lilia about this exciting live reporting that hopefully will shed more light on this issue that has polarized a nation.

Monsters and Critics: This six-part series, please give us the broad strokes for people to understandand spend time with people rather than just breaking news.

M&C: Two-part question. As an investigative journalist, this is a very dangerous time with the murder of Khashoggi allegedly by the Saudis, but all over the world. Journalists are being killed and imprisoned. Please talk about how you protect your psyche and your safety.

Lilia: I think as journalists, I think that people who do the kind of journalism that I love to do, there’s probably some kind of something wrong in our head in terms of perceived fear. I don’t think I feel as much as fear as some people. It’s very delusional.

You kind of walk around thinking that nothing’s going to happen to you, and I think that’s the initial drive, like you’re, “Oh, I’m fine. Nothing’s going


or a veteran role player on a new contract or an experienced minor-leaguer.

But while Dennis Rasmussen and Tanner Kero are solid bottom-six centers, Krugers don’t come along all that often.

“Organizationally, that’s something that’s looked at a lot, whether it’s the money side of it, the business side of it, the hockey side,” coach Joel Quenneville said. “There have been some [expansion-draft] discussions, but it’s a little bit out there and really not on my front burner.”

But the Hawks will have to make a difficult decision on Kruger eventually because he’s somehow invaluable and overpaid — a luxury. And one the Hawks might not be able to afford.

“I’ve never been a guy that has really paid much attention to stuff like that,” Kruger said. “That’s just how I am.If you have Twitter, you probably see a lot of rumors and stuff like that. I’m pretty protected from that. I just focus on myself, and whatever happens, happens.”

Follow me on Twitter @MarkLazerus.

Email: mlazerus@suntimes.com


Beginning in 2009, telemarketers will be banned from making "robo calls," those pre-recorded sales calls that seem to serve no other purpose than to drive people crazy. The bad news? Charities can still harass you as much as they like. [WSJ]permanent personality changes. A qualitative 2016 study by Hariz, Limousin, and Hamberg found that for patients receiving DBS to treat Parkinson’s Disease, the perceived benefit of having less invasive, more predictable tremor conferred tolerance to adverse events. The importance of the participants personal accounts was that it allowed researchers to understand the social and relational side effects, both positive and adverse, that was conferred to patient livelihoods due to implantation. For example, the study’s participants described having less dependence on family members, and others described not wishing to return to careers post-implantation due to the fear that stress may cause relapse of tremors.

That being said, the perspective of implanted patients with mood disorders remains poorly characterized. To address this issue, Klein et al. (2016) interviewed patients who underwent


prototype P92 models. This model comprised a B50 engine in a BSA Fury/Triumph Bandit frame using Isolastic mountings from the Norton Commando. The US DOT had mandated that all motorcycles sold in the US should have a left hand gear change. The B50 had the gear lever on the right, so to comply with this requirement, the engine was tilted forward in the frame and a gear linkage run under the gearbox to provide a left hand gear change. The model never progressed to production.

B100 V-Twin (with two B50 cylinders )
Specialist motorcycle designer Gerald Fitzpatrick created a 1000 cc BSA V-twin using parts from two B50 engines in 1977. The frame was a slimline featherbed Norton Atlas. Triumph considered putting the B100 into production but were not able tocortical neurons were transfected with M1CY-Flag and M85CY-GFP, fixed and stained for β-tubulin (not shown in the overlay). Scale bars: 20 µm.

These results confirm a different localization of spastin mutants in cortical neurons as observed in HeLa cells and suggest a weaker affinity of M85CY for MTs in comparison to M1 mutants.

Spastin mutants increase the level of acetylated tubulin {#s2c}
--------------------------------------------------------

Acetylation is a post-translational modification (PTM) of tubulin frequently associated with long-lived MTs ([@DMM033704C24]). Missense mutations of M1 spastin have been associated with increased stabilization of the MT network ([@DMM033704C18]). Accordingly, we observed that the expression of all spastin mutants significantly increased the level of acetylated tubulin ([Fig. 4](#DMM033704F4){ref-type="fig"}). Quantification of the average intensity of acetylated tubulin in M1CY-, M85CY- and M1Δ-expressing cells demonstrated an increase of this PTM by 59.3±4.7%,


high risk patients it may underestimate the risk. The logistic Euroscore can predict the risk more accurately, especially in high risk patients.[@ref14] So this study aimed to evaluate the accuracy of logistic Euroscore (European System for Cardiac Operative Risk Evaluation) in predicting perioperative mortality after cardiac surgery in Iranian patient population.

Methods {#sec1-1}
=======

The present study included 1511 patients undergoing coronary artery bypass graft (CABG) during 2 years from 2007 to 2009 in Sina hospital of Esfahan. The sample size was defined based on previous studies.[@ref6] All patients gave their written informed consent before their surgery and entering into study. The study was approved by the Research Ethics Committee of Isfahan University of Medical Sciences, Isfahan Sina Heart Center.

Data for the studied patients including demographics, clinical characteristics, laboratory data, medicalcalibration of the Euroscore model.

Data analysis was performed by the SPSS soft ware (version 14, SPSS Inc., Chicago, IL).

Results {#sec1-2}
=======

[Table 1](#T1){ref-type="table"} shows clinical and demographic characteristics of the studied population. Totally, 24.9% (376 patients out of 1511 patients) were female and 74.9% (1103 patients) were male. Mean age was 59.7 ± 10.2. 149 patients were excluded from our study because of not accessibility. Mortality rate in 1362 patients was 3.6%. The logistic Euroscore predicted perioperative in hospital mortality rate of 3.9%. Logistic regression model calibrated well to our sample and gave P value of 0.89 in the Hosmer-lemeshow chi-square test. [Table 2](#T2){ref-type="table"} shows predictive value of Euroscore items. Odd ratios calculations revealed that predictive values for well-accepted risk factors such as unstable angina, sex and renal failure were


not significant. Left ventricular dysfunction, older age and neurologic dysfunction were significantly related to the mortality rate.

######

Clinical and demographic characteristics of the studied population

![](JRMS-16-787-g001)

######

Association of Euroscore risk factors of study population and occurrence of death by multivariate logistic regression analysis

![](JRMS-16-787-g002)

[Figure 1](#F1){ref-type="fig"} shows percent distribution of risk factors among the patients. Mean LOS, ranging from 0 - 49 days, was 2.5 ± 2.5 days, and median was 2 days. Prolonged LOS occurred in 18.3% of the patients. The AUC for the logistic Euroscore was 0.66 (95% CI) \[[Figure 2](#F2){ref-type="fig"}\]. Using the receiver operating characteristics (ROC) curve analysis, we found an optimal cut off point with 66% sensitivity and 62% specificity that corresponded to the score of 0.028 (in logistic Euroscore) being able to separate death probability fromfor Euroscore (78%).[@ref4] In Nashef et al. study in North America, AUC for Euroscore was75%.[@ref16] Other similar studies also reported near results.[@ref1][@ref18]

Since the least AUC for Euroscore model in most of the studies was 75% and the AUC \>70% usually demonstrates a good predictive value, it seems that Euroscore risk model has less discriminatory power in predicting preoperative morality in our patients. In fact, according to the results, this risk model did not accurately predict preoperative mortality; therefore, it may not be suitable for use in our patients' population.

In our study, 18.3% of patients had prolonged ICU stay. This was almost similar to Wong et al. study result in which 17% of CABG patients stayed more than 2 days in the ICU.[@ref19] Although, Pitkanen et al. reported 4.8%


age limits of the oldest and youngest populations, respectively, by comparing population synthesis models. We will address this issue in our upcoming papers.

This paper is based on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan. We are grateful to the entire staff at the Subaru Telescope. S.-J.Y. acknowledges support by the Mid-career Researcher Program (No. 2019R1A2C3006242) and the SRC Program (the Center for Galaxy Evolution Research; No. 2017R1A5A1070354) through the National Research Foundation of Korea. N.A. is supported by the Brain Pool Program, which is funded by the Ministry of Science and ICT through the National Research Foundation of Korea (2018H1D3A2000902).

Anthony-Twarog, B. J., Laird, J. B., Payne, D., & Twarog, B. A. 1991, , 101, 1902

Anthony-Twarog, B. J., & Twarog, B.21 U.S.C. § 381, and notice was given of opportunity, among other things, to present evidence as to the manner in which the coffee could be brought into compliance with the Act.
On December 1, plaintiff filed an application for authorization pursuant to 21 U.S.C. § 381(b) to attempt to bring the 5,000 bags of coffee into compliance with the Act by the procedure of "skimming the coffee to remove molded beans" and "drying the coffee out to remove wet beans." This authorization was given on December 4. Reconditioning of the coffee had actually begun, however, before the approval was given because of the fact that, if not dried immediately, more coffee would mold. The coffee had been moved to and the reconditioning was done at the warehouse of


571, 88 L.Ed. 733, the Supreme Court said:
"* * * When Congress passes an Act empowering administrative agencies to carry on governmental activities, the power of those agencies is circumscribed by the authority granted. This permits the courts to participate in law enforcement entrusted to administrative bodies only to the extent necessary to protect justiciable individual rights against administrative action fairly beyond the granted powers. The responsibility of determining the limits of statutory grants of authority in such instances is a judicial function entrusted to the courts by Congress by the statutes establishing courts and marking their jurisdiction. * * *"
To the same effect Waite v. Macy, 246 U.S. 606, 38 S.Ct. 395, 62 L.Ed. 892 (1918); Hammond v. Hull, 76 U.S.App. D.C. 301, 131 F.2d 23 (1942);“that the gall and vinegar, or myrrhed wine, offered to our Saviour immediately before his crucifixion was, in all probability, a preparation of Indian hemp.”

(Transcripts, Ohio State Medical Society 15th annual meeting, June 12-14, 1860, pg. 75-100.)

From 1850 to 1937, the U. S. Pharmacopoeia listed cannabis as the primary medicine for more than 100 separate illnesses or diseases.

During all this time (pre-1000 B.C. to 1940s A.D.), researchers, doctors and drug manufacturers (Eli Lilly, Parke-Davis, Squibb, etc.) had no idea what the active ingredients of cannabis were until Dr. Mechoulam discovered THC in 1964.

20th & 21st Century Research

As outlined in the previous chapters, the American Medical Association (AMA) and drug companies testified against the l937 Marijuana Tax Act because cannabis was known to have so much medical potential and


narcotic – having no known medical use. His successor, Robert Bonner, who was appointed by Bush and kept in office by Clinton, was even more draconian in his approach to hemp/marijuana as medicine. Bush, Sr., Clinton and Bush, Jr.’s DEA administrators have all upheld policies far worse even than Bonner’s.

So…if all this has been known since 1975, what is our government waiting for?

2007: DEA Judge Rules Against the U.S. Government’s Monopoly on Pot Production

Washington, DC: Drug Enforcement Administration (DEA) Administrative Law Judge Mary Ellen Bittner ruled February 12th, 2007 that the private production of cannabis for research purposes is “in the public interest.” Her ruling affirms that the DEA, in 2004, improperly rejected an application from the University of Massachusetts (UMass) at Amherst to manufacture cannabis for FDA-approvedel Tiempo (Bogota), reported in 1983 that these same anti-marijuana crusading American pharmaceutical companies are guilty of a practice known as “product dumping,” wherein they “sell on the over-the-counter markets of Colombia, Mexico, Panama, Chile, El Salvador, Honduras and Nicaragua, over 150 different illegal, dangerous drugs.” This report has not been disputed by the U.S. government or American pharmaceutical companies and the practice continues in 2007.

Some of these drugs have been forbidden by the FDA for sale or use in the U.S. or its counterparts in Europe because they are known to cause malnutrition, deformities and cancer. Yet they are sold over-the-counter to unsuspecting foreign consumers!

The World Health Organization backs up this story with a conservative estimate: they say that some 500,000 people are poisoned each year in


it weren’t for the illegal pot dealers (before Proposition 215), there would have been no marijuana and I wouldn’t be alive today. Marijuana eases nausea and makes it possible for me to keep down food and the pills I must take to combat my diseases. Fuck the federal government. Use it if you need it.” He was later arrested by the DEA. His mother put up her house for bail. The DEA said if he was caught using pot she would lose it. He stopped using pot, his health quickly declined, and he passed away in June of 2000.

Chapter 7: https://jackherer.com/emperor-3/chapter-7//older/ than Kehemath by quite a few turns. She's got energy and little control. But, so did Kehemath. We'll work with her, I just hope Nell is open to our help…she seems a little…not defensive, but accepting that this is just the way Wayneth is. Which I /totally/ understand. I was the same way with Kehemath, but." Shrug.

"Mm. That would be my assessment," A'lory strokes his chin thoughtfully, eyeing Sienna with a ruminating sort of frown. "I /suspect/ — " One cautionary finger is raised against certainty. " — that she has coddled the dragon due to her previous… /experiences/… at her Weyr of Impression."

Sienna tilts her head a bit, opening her eyes to watch the Wingsecond. "What happened where she Impressed? She seems almost to expect that


the Weyrsecond. "So perhaps there is that issue as well. Protective, not wanting to take control. I understand it. Hopefully we can help her, since W'rin has tasked us with it, in a way. We're supposed to keep her moving /all/ the time. To tire her out. I think after this Kehemath and I are going to go try and find some toys for her. Things Kehemath enjoyed that I think she will too."

"I believe that's the case," A'lory is in perfect agreement eith hiscurly-haired companion; the very idea of starving a dragon is preposterous. "Mmm. I do wonder how much of her behavioral issues stem from the way her former Weyr mishandled things."

Sienna snorts, "Probably /most/ of it," she says. "I mean, Kehemath and I didn't havetell W'rin? Or should it be a surprise?"

A'lory is /always/ thinking of food, even thoygh he eats so little of it himself. "Well," And here, the bronzer is all boyish charm as he tilts his head at Sienna. "People will work the harder for good food." Or BRIBES. To continue: "Kanga would work perfectly for that. And I do believe W'rin would do well with a surprise or two."

Sienna chuckles. "Fine, I'll make sure we have food. The kitchen is clean enough I can cook in there, finally, and I'm starting up my cheese cave again…" Then she laughs. "Okay, but I can't lie to him. If he catches wind of it and asks me what I'm doing I'm going to tell him it's a project for /you/."


Children’s Fiction Prize for novels including the bestselling trilogy Chaos Walking, and books such as More Than This, The Rest of Us Just Live Here andperhaps most famously, the extraordinary A Monster Calls.

Reviews

“Heartwarmingly Heartbreaking!!!!”

This is a beautiful little novel, with a thought provoking and heart warming storyline.
When I first went to read this book, I was expecting a sweet story about a friendly monster who arrives to help out a young boy....
More

“A Monster Calls”

There’s not much to say about this novel that hasn’t already been said. It is a beautifully written and illustrated piece of work. It was very short and I managed to read it over a couple of nights but it will...
More

“A moving tale for teens”

Made all the more poignant by the circumstances of its creation,details of Waterstones’ special offers.

When will my order be ready to collect?

Following the initial email, you will be contacted by the shop to confirm that your item is available for collection.

Call us on or send us an email at

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Please try again or alternatively you can contact your chosen shop on or send us an email at


luck isn’t the only rumor that follows dark-furred kitties into the present. For decades, many animal shelters have refused to adopt out black cats on or right before Halloween out of fear they will be tortured or sacrificed, Kate Knibbs writes for Gizmodo.

"This is a time when blood rituals take place," Hedy Litke, director of animal placement at the ASPCA, told K.C. Baker for the New York Daily News in 1999. "Black cats are often sacrificed.”

First things first: there’s no evidence suggesting that people go out of their ways to do bad things to cats on Halloween. However, persistent rumors about cults and crazy people seeking to sacrifice black cats on the spooky holiday have been enough to make many animal shelters put a hold on adopting outaround the cage and bites it using its sharp front incisors, usually aiming for the mouse's head, neck, or upper back. The first bite is frequently fatal, but the mouse may delay the rat's attacks by defending itself (by rearing up and boxing with its front paws or laying on its back). Eventually, however, the rat delivers a fatal bite. Mouse-killing behavior is very rapid, lasting only a few seconds (Hsuchou et al. 2002).

The preferred area to bite is the back: out of 671 mice killed by rats, 89% were bitten on the spinal cord (specifically: 65% neck, 13% thoracic, 11% lumbar). Only 7% were bitten on the belly and 4% were bitten on the head (Karli 1956).

Do rats eat the mice they kill?

Karli (1956) found that all


tag:blogger.com,1999:blog-32458049.post9097008544791285199..comments2018-05-10T06:59:56.160-04:00Comments on Please Don't Pass The Nuts™: Hervé This at The James Beard FoundationAllergic Girl®http://www.blogger.com/profile/14903866598372396735noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-32458049.post-53559370663014446792007-12-08T10:04:00.000-05:002007-12-08T10:04:00.000-05:00hey sheltie g, are you also a chemist or a secret ...hey sheltie g, are you also a chemist or a secret foodie?Allergic Girlhttps://www.blogger.com/profile/14903866598372396735noreply@blogger.comtag:blogger.com,1999:blog-32458049.post-29840412322181560722007-12-08T10:01:00.000-05:002007-12-08T10:01:00.000-05:00I read Herve This' work. He's very interesting.Sh...I read Herve This' work. He's very interesting.

Sheltie Girl @ Gluten A Go GoSheltie Girlhttps://www.blogger.com/profile/00017566413309758029noreply@blogger.com# Revgrad
A PyTorch implementation of '[Unsupervised Domain Adaptation by Backpropagation](https://arxiv.org/pdf/1409.7495.pdf)'.
The contributions of this paper are summarized as follows.
* They use adversarial training to find domain–invariant representations innetwork. Their Revgrad exhibit an architecture whose first few feature extraction layers are shared by two classifiers(domain classifier and label classifier) trained simultaneously.

## Requirement
* python 3
* pytorch 0.3.1
* torchvision 0.2.0

## Usage
1. You can download Office31 dataset [here](https://pan.baidu.com/s/1o8igXT4#list/path=%2F). And then unrar dataset in ./dataset/.
2. You can change the `source_name` and `target_name` in `Revgrad.py` to set different transfer tasks.
3. Run `python Revgrad.py`.

## Results on Office31
| Method | A - W | D - W | W - D | A - D | D - A | W - A | Average |
|:--------------:|:-----:|:-----:|:-----:|:-----:|:----:|:----:|:-------:|
| Revgradori | 82.0±0.4 | 96.9±0.2 | 99.1±0.1 | 79.7±0.4 |


Modern Nude Prints

The history of nude pictures has a lot of controversies. At some point in history, these images were used surreptitiously to provide inspiration to those who reveled in their use. However, they were publicly condemned. At some point, people started using nude artwork for purposes of education and in galleries.
This continued until several societies began to widely accept them and the trend was further replicated with the widespread use of internet. It isn’t a big deal anymore to see a room decorated using nude posters. This could be in a club, living room, bedroom, or any other place deemed appropriate by the user. Admittedly, these images have conspicuous inspirations and have a unique ability to trigger emotional reactions by just their sight. Look at "The Shower"= "";
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Clinical Presentation {#sec1-1}
=====================

A 61-year-old woman underwent MRI scan of brain (**[Figure 1A](#F1){ref-type="fig"}**), followed by conventional angiography (**Figures [1B](#F1){ref-type="fig"} & [1C](#F1){ref-type="fig"}**) and magnetic resonance cerebral angiography (**[Figure 1D](#F1){ref-type="fig"}**, conventional angiography was performed for more specific details regarding the findings of the initial MR cerebral angiography) as part of the ischemic stroke work-up for recurrent episodes of right hemiparesis and expressive aphasia.

![Patient's MRI depicting sagittal view of T1 weighted image **A)**, digital subtraction angiography **B & C)**, and magnetic resonance angiography **D)**. RICA- right internal carotid, RCC-right common carotid](Neurosciences-20-179-g001){#F1}

Questions {#sec1-2}
=========

Interpret the angiographic findings.

Answer {#sec1-3}
======

Parasagittal T1 weighted cranial MRI (**[Figure 1A](#F1){ref-type="fig"}**) shows the configuration of flow voids (arrowheads) in the presellar segment of the right internal carotid artery (ICA) resembling the Greek letter t (spelled tau). This appearance is more obviousmagneto-resistance in a two-probe ring geometry within a tight-binding formalism. They have presented analytical results for ordered single- and double-ring structures and discussed the localization effects due to disorder in such systems. AB effects for bound states such as neutral excitonic particles have also recently been studied [@WarSHB00; @Cha95; @RomR00].

In comparison, the behavior of the magneto-conductance in systems having serially connected rings, has received little attention. In one of the early studies on serially connected rings Deo and Jayannavar [@SinJ94; @JayS95] discussed quantum transport in these systems. The ‘band formation’ in such geometries has been analyzed and some magnetic properties of loop structures in the presence of an AB flux have been discussed. Takai and Ohta [@TakO93] have also addressed similar problems where both the magnetic flux and


as shown by solid dots at these points.](figs/fig-TrP_phi.eps){width="0.95\columnwidth"}

Therefore, at $E=\epsilon$ and at arbitrary flux, not equal to a special value such as above, the transmission coefficient across an array of this type of rings will decay exponentially as the system increases in size. This can also be checked using the formula for the transmission coefficient. For the special values of the flux mentioned above the transmission coefficient is precisely [*unity*]{}. This implies that for $E=\epsilon$, we can achieve totally ballistic transport by tuning the flux to a specific value. This is an example for an extended eigenstate under the influence of a magnetic field [@AldGC92; @SinJ94; @JayS95]. The phenomenon of full transmission at these specific flux values can be understood if we look at the values of $\tilde\epsilon$study the transmission coefficient, let us first consider the case $\phi=0$ such that $$\label{eq-10} \mbox{\boldmath $P$}_{\rm even-odd}({\phi=0})=
(-1)^p \left( \begin{array}{cc} -2&1\\-1&0
\end{array}\right) .$$ A product of such matrices will look like [@JordanForm] $$\mbox{\boldmath $P$}_{\rm even-odd}^N({\phi=0}) = \left(
\begin{array}{cc} N+1&-N\\N&1-N
\end{array}\right) .$$ when $N$ is even. A similar expression can be worked out for odd values of $N$. In either case, it can be checked from Eq.(\[eq-transmission\]) that with $\epsilon_0=\epsilon=0$ and $t_0=t=1$, the transmission coefficient exhibits a [*power-law decay*]{} for large values of $N$, i.e., $T \sim 1/N^2$. At $E=0$, the matrix $_{\rm even-odd}$ is exactly the same as the transfer matrix for a periodic chain having $N$ sites with $\epsilon=0$ with the electron at energy $E=-2t$ (which defines the band edge of the infinite ordered chain). Hence the ($E=0,\phi=0$)-combination for a periodic


Smart!!! Glaser Dumb!!!,” wrote another. Not all of the comments added to the petition were so staid or tongue in cheek. “Selling on a loss to gain market share might work for large profitable giants with money to burn,” wrote one signatory. “But for a worthless company like Real, with history of losses quarter after quarter, it is a short-cut to Chapter 11. And I say more power to Real, please spend your way to bankruptcy ASAP. The whole market will heave a collective sigh of relief and your 49c customers will get what they paid for, support or rather lack thereof, from a bankrupt company.”

Its first petition gone horribly awry, Real launched a second, this one with comments disabled. But it too drew the ire of thosesupport his conviction and that the district court
sentenced him in violation of his sixth amendment rights. We affirm his conviction,
but we vacate his sentence and remand to the district court for resentencing.

      Terrance Fuller also appeals his conviction and sentence on one count of
conspiring to distribute cocaine, see 21 U.S.C. §§ 841(a)(1), 846. We affirm his
conviction and sentence.

                                            I.


Had to make changes to story. The continuing adventures of the Black Tigers started in Prince of Darkness. They are on their Hawaiian Honeymoon. WARNING: please read Prince of Darkness first. Rated for language

This fiction is based on a picture by CarbonF over at DeviantArt. Ron has a very important mission to complete. The problem is he is so nervous and scared he can barely think straight. Please read and review.

KPSpidey fusion Who am I? Do you really want to know? All my life I was KP's sidekick, but in one startling moment ... I learned that with great power comes great responsibility, and everything changed forever. Who am I? I'm SpiderMan. FINISHED

KPPower Rangers crossover. A powerful evil is unleashed, which Kim Possible alone cannot handle. Now, aMiddlesex School , Governor Dummer Academy, and Belmont Hill ) followed by New England private colleges.They are confident and unafraid to express their own styles and be daring in their fashions. Preppies vacation on Nantucket, Martha's Vineyard, Delray Beach , and on the coast of Maine. These vacation locales are places their families have been going to for years, and have histories there.It is a common misconception that preppies are snobs. Many people view them as unapproachable, and as a result mislabel them. Preppies are not as rich as people may think they are, but they are often well off. They buy into classics rather than trends, and don't change their lifestyles with fads.Preppies tend to have bizarre connections with other preppies they meet, always finding mutual friends/


in the development and progression of cancer by regulating cell proliferation, differentiation, apoptosis and metastasis \[[@R19]\]. Like β1 integrins, IGF-IR signaling has been reported to mediate resistance to radiotherapy \[[@R20], [@R21]\]. Together, these receptors play a concerted role in radio-resistance of cancer cells \[[@R3]\] and unraveling the nature of these interactions is expected to contribute not only to understanding the mechanisms of resistance, but also in the identification of novel therapeutic targets.

Here, we have studied β1-mediated downstream signaling *in vivo* in prostate cancer resistance to hypofractionated radiation. We report that JNK inhibition compromises the beneficial effects of radiation therapy in TRAMP mice carrying conditional ablation of β1 (β1^pc-/-^ /TRAMP), and results in a significant increase in prostate tumor growth associated with increased FAK expression and activity in thesestaining was scored as FAK positive; FAK expression was scored using a 1-3 arbitrary scale in the FAK intensity column. -, indicates undetectable levels.

![Tumor growth upon irradiation and JNK inhibition in β1^-/-^/TRAMP mice is associated with enhanced FAK signaling\
**A.** Induction of FAK expression and phosphorylation in prostate tumors from β1^pc-/-^ /TRAMP mice. Immunoblot analysis of prostate tissues from β1^pc-/-^ /TRAMP mice treated as described in Figure [1](#F1){ref-type="fig"}. Prostate tissues were snap frozen. Tissues were homogenized and lysates analyzed by SDS-PAGE using Abs against FAK^pY397^ and total FAK. ERK1/2 was used as a loading control. **B.** Immunoblotting analysis of prostate tissues from β1^pc-/-^ /TRAMP mice showing AKT^pS473^ and total AKT in prostate tissues as described above in Figure [4A](#F4){ref-type="fig"}. ERK1/2 was used as a loading control.](oncotarget-07-52618-g004){#F4}

![Irradiation coupled with JNK


high FAK expression and phosphorylation associated with tumor progression upon radiation, are consistent with these studies and collectively highlight a central role of FAK in therapeutic resistance.

Activation of AKT has been reported earlier as an important predictor of the probability of PSA failure and a marker of clinically aggressive prostate cancer \[[@R40]\]. There is a significant interest in developing effective strategies to target this pathway \[[@R41]\]. In our studies, however, AKT activation in irradiated prostate tissues does not change upon JNK inhibition ruling out a significant functional contribution of JNK-dependent AKT activation in prostate cancer development in SP-treated β1^pc-/-^ TRAMP mice. Finally, although sustained FAK expression and activity have been reported to be essential for androgen-independent formation of neuroendocrine carcinoma \[[@R23]\], we observe significant chromogranin expression in TRAMPthe Reddit Machine Learning channel, with many concerned that academic inclusivity was at risk and that other academic tools or platforms such as the Cornell University’s repository of electronic preprints arXiv could also be subjected to US restrictions. A number of Reddit users are suggesting all IEEE publications be moved under the umbrella of IEEE Switzerland to avoid such US government restrictions.

The IEEE has more than 423,000 members in over 160 countries. It publishes over 100 peer-reviewed journals and about 30 percent of all electronics engineering and computer science literature.

UPDATE：

In a statement released this afternoon as an official response to the public, IEEE stressed that their compliance with US trade restrictions should have minimal impact on IEEE members. Below is the complete text of their statement:

IEEE would like


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// (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANYi sd\v vzsv i â– -. rv-m xt no fiirt , careful to uppr.se at rangers where an.uae i â€žâ€ž in are to is hud i took up i ht.lw i pamphlet purporting to be an aocounl o ho nun-ill's collection ol pointings un determined to go und see ibem it was out difficult .Â» find a-here they were ex hibited as it was in the aforesaid place i where 1 bud hesnl the historical speeoll i and seen ihe sultan a bignawte the elite it seem i 1 Â»Â»â– Â«*â– Â«"' lis | hind more in lho after d than in lho i morning end i was nol a little gratified in : finding ihis io be true on seeing lha per sons who were aimed in


the long hue of lamps â€” the increased crowds of people nuiko every thing tnnrtj lively antl cheerful i was pleased with the beautiful iriinsp.iriiurie-s which i im-ii.-iu ui various places und with the ingenious contrivances which are resorted to lu act every thing oil to greater udvantase nol withstanding the opposing darkr.es j auw u i.uiuber of people moving in the di rection oltrutimort st v 6nd learned that it was to see the plamtariuin of mr kyle in which is exhibited a view of the greut comet that is expected .,, visit ua shortly as 1 hope to see this celefrtinl wonder in ho board aud i*p..n heavens 1 decline goihg to inspoct the artificial one inuuufao tured by mr kyle in pasmg ulotig i noticedio 1','iq a attempt waa hsnade by the british government men io ' italic li wasiiii-.gti.il ; the rebel leader aa lh wus styled by mixing poison with hie lf,Â«.d ut n dinner party but was timely lunough discovered to be prevent i*ur hsuiug these reflections i found that i bad hu ii ,,',,â– , i el ue into thn park â€” it waa h'.tii . the crowds had disappeared from i limed erey uud u solitary watchman was l.-ulling -â€¢ pus iu o'clock from the silent ip.ir.ic al lho city hall it was then that larnumiie frum my reverie and pondering hen the manner iu which the day had lean hsprni that it hud pus-e.'amay in frivolous haiiiuionienl productive of mi solid udvan itag .'â– till sell


â€” if uo good to nia.illi.hl.it - l s then fur the first time thut i bngan it feel unhappy i felt sir a curious hs.'iis'iiii,u about the epigastric ri,.<ioos hnn.l 1 experienced that vtira.ii y aad it i pi ness i if nil things which makes ua lt.iv ii till but ol llx.kin i ri.ural ii perceived alight "-!,-.. i inkling in th lilisl.'iu e â€” 1 i'nllowe soon fund hinvstill iu ii sniiir ii upar'uientj hub-ire a good put ,.. - i d a hoi ' kirchwasser were ib . . an rf.-uviiyj h,,,c â€” upon leaving i complimented tl.e ma le d-iiio en the choice flavor of his viand h.,n i the excellence of his own character lin aitting up at so lute an hourand h-suf litis res for be benefit of his fellow ttna htttrcs and 1 could not have be , mistukea iks to tl.e disinterested goodneas ofthe vie hlular for on bis turning l.is head round i i'.rl 1,1 oo the poetcrinr side of hia cranium ithe organ of benevolence developed to th hdinienaioiin.f an oyster shell h such are the br.of albeit unimportant of a day ,.! itappinose for the hillsborough recorder no ill ftliis t h il,...it 1 '. j |â€ž ;' a vt"3"iir llirh i 0 t;,rh 0 lhe in that i in ;â– ili-.-l to the .,,, |, ,â€ž i'ti i , rt >,, 3h pro assit.intl.m no t the fl the nlil-lib i h tariff to a mun i 1-h fnr in t ti..il


i lh lie h the i stnlcs.h t h tin t"l ,,, â– ;. b . th bill ilie i int i elii-.t.b those iâ€ž<i',ih revenue *,<-;, r*m .,, in i-i h to the i i i t''.h to iii ll i-illitll.i'ucllh or about i rrom the ii.i'.lb and he ot the -> i â€¢ i no .,, ' h h'ul.'h ih in i elude v liiir.l.b the to ihcuih tii,'h he benefit n those h our now to do <â– : ' mil knov the mo nt,i,,,i.h then lin he iioitltlh vear !"â– ' rei-iil i ii"ii-h ne use und a i on the sum of 3."*,0,000 upon the ncea-tionsm ho heiieiit of certain individuals forth lie oil the our own coun our to n.-h iii.'h whomconstitution philosopher in regard lo the tilings of ' '- h ever that these seven liuuilri-.l sugar ery day lift and that he experienced moroh planters pick tbe pockets of all the inhabit w . c . s ,, r ecli amos excellent rr Â«Â«â€¢ enjoyment in the parade l'a,-â€žurt aitt-ui'liiiscoun.p tu like manner&loa like vicw clf lho sp li was publishsd.no than the grecian sage ever possessed inh extent ia perhaps none of our concern and , si ,â€ž ,.,â€ž new y ork - journal i the solitude l lus cave i cermiulv nu consolation to ns i will câ€žm.n-.ve in which the or u tits of it was in the midst of meditations !..*-â– make no calculation of what he amount the omtor wm6 apwn to


be both unsound be that we were engaged in perusing nf plunder is my reader can easily do il .,â€ž,â€¢â€žâ€ž,â€žâ€ž,*,,â€ž.,,Â». 1 ia too long lor entire the ramwer that admirable pro â€ž.., n â€ž(â– if he is not already sick at the oootempla ,â€žâ€ž,.,.â€žâ€žâ€ž ;â€ž â€ž ur ,,;,,â€ž.,.. | llt , â€ž s lllt â€ž f the bntlrt n.oml.sl a-bonwet ii upon tl.eh tion uf such oppression thoroughly eon t |â€ž. pl ,. hh11 i lv a a g i humor with which l " !,,, "> "', *','** "'' '""- '' "â– ''"* i ' '*â– vinoed of the enormous injustice and folly ,. â– ' wriltci * we ,, ivo ,| 1u ii w i l;x - uni hundred years lh ught l had anp-h nfthelike impoeitions to ii iron salt nsolas {'Â£& cemmdbitiee has thing lo pur ad to roe ou reflection to think the , â– ses crockery ware glass hardware un Â»^_ ,>,,,.,â€žâ€ž fabrns to them ihev are sucoeseive bapp days could be a lulled i â– paper book spirits oil oottoue a wool l beyond their raacb whether the "'*" ''" ul "'' "" "' , v Â«* ""'*â– lens dec ate constituting almost ail th ,.,'â€ž, a ( , jj â€ž , â€ž,â€ž,â€ž.â€ž.-â€¢ a lt,s ! pâ€žâ€žr aaadad had be lumte i the tunc to a â€ž,..-â– articles we have to purchase mr lay p enmv ( vbd ia 'â€” t .- new york !â€” p.w.r ment.an hour ir n day â– in ins scheme of compromise proposes


t n ,. v , england ! we can tell mr t'biv of Â«Â« wils wl11 ' a v,,w loaacertain i ie truth allow the farmer as an indemnification roduct at the f^rt however of which of thia conjecture liat we eat apart â€¢ da for these taxes .â€ž import free of duty or k ,;__, perhape aware crops , lf y ...Â» hid we u-.h .â€ž.â€žâ€¢ happy â– uearlv so dirks dn/mers eatliuis nt i>.x | . â€ž^ ' a \ i . m ,. i a mort profftable a ihe sun had l >.'. r slid iom '<]"*"â– hits with sundry others which a farmer jjjj , 11 ,â€ž u . ul i cr , ,, wa , â€ž evrr ea,>.t,l i o tall spires dl,u..rv iieoi.r s poet of lhe c nnv au olher was .,,' a 1 wrirnn â– *â€¢..-'-. a â€¢.Â«:,.... f ni liter for e sis . b .,â€ž. c lo > .-'â€¢ ii 11 ' urÂ»iu,'i pro hdlof liire.auduep^tod somewhat njd ijut i*se otiubip uÂ»nautuctct.iui lw*u bllt i i'r >'â– it ll 1 ' i i .â– : -,,' ; , .' ., ,,,,., ******* . ' , ,, ,!â– tt - *************'â– other advantage it became the weal hi n.g in and ro without nnv steady l n h e*t sn-it in america recently tin bttempl p so i.iviow â€” pleasure ni'iener ial.--s s l.y^^h i is beet mode lo frighten lhi â– â€¢<â€¢ fearli **â– surprise und it is difficult to arrive it it i'.'h freemen


if mr gallatin mr smith and mr 8ar and in imitation of his lieighbort u i till diet have received the two first are was in like manner put on ida floor wui.h gentlemen venerable in age and in publi the following notice : â€¢â€¢ i p ,-,,...â– ,â– eiage^^b service in both fl respects at least a loner pwaa almoel salted with iiel they are lh eeirii nl mr clay and upon determination to take this opportunity < i l all the rei-.tgni ,.< cil ilities < i gentleman make an inspect iun nl a good many liwrll-h ly intercourse entitled to his kindness ings and of their inmates h tims up-h antl respect neither had given the cared accessible m spe tutors l,m tâ€ž,*l lightest causeblows upon his ingtoll ha i a lively an i agreeable appear i anvil which il could poorly resist a ance and was mnch euf-iiaui.-d iuu^h dr clhy cannot answer him either wilh rido to a distant purl of the citj â€¢' i-ppi-ig^h facts nr arguments lie resorts to tho law here and there to lend some and iake.nl of a certain code in thai case made and ti.er travellers ou m return whilst i proi nl â€ž i ami ial â– lo abusing mr barchet walking in the neighborhood of park row i in e ihall leave him in the hands ,, i the my attention was railed in u vehicle sim-^h blacksmith upon ins anvil and under har lo the one i bad jusi h-l'i although


i ilia hammer the iron ribe of the american not quits so handsome li was nark 1 1 systom will crock like the bones of a ml â€¢â€¢ n general uuios dry uock und i.i lhe jaws of n terrier i pon lhe wall st j^m whole matter we say il these are the l otairvi _- , number of pei_onsen-h manners ofthe american system ere are i . in , : ,,_ , _ .,.â€ž.,.,â– ,.â€žâ€ž.,. m j gb , ,,- holnt , fl still for tree importation of the foreign ..,â€ž.,.,>, ,,| (| ,.,., i n view eo without asking â– coinmoiliiy vxe beg that wherever we que ltlona i doterm dtojointhem â€¢'>.â– â– may go we may net be ehut up to the do soimju1|d ,â€žâ€ž.â€ž,.*,,., advancing wards â– trjestic iniiiiiifai-ttire but mr clay la ve the eastern hide f tl mu ,,, a,â€ži i was i ry polite to the irish he saye : tjfall â€žâ€ž, lon , ,, learning that thn party wus h foreigners none umnlgnmnte themselves ik1uiu1 u|1 bhi viifji in t|w . oiu rf t m so quickly will our people as the i-.n.c , m a hip launch when wo arrived the â– raid ue in some nl the visions that have â€ž,â€žâ€¢â€žâ€ž.â€ž â€ž.,.â€ž. |â€ž, sv wllll s e hum â– passed throng my imagination i have sup n)prs .â€žâ€ž| ,|, 0 s |â€ž ir ,. : , w l,ieh npli-l'l th i po-nil that ireland was originally pan b hip on the stocks werefolling i


n..-i i and parcel id hus continent and that l.y u ,^ 3m , .. u . i)qiu .â€ž.,*. myv â€ž uilu | inl , â– some extraordinary convulsion of nature | k . r pmnrr fcir.<-ti it was torn from america aad drifting ., . , ... , , ,. 1 i " i-inr as t he bosom of the avvnii across the ocean was placed in the unfor ' tunaie vicinity ofg britian tba same that rises graceful e'er tbe wave m open-heartedeeaa â€” the same generous hos alter tins 1 directed my course hy the i piiah.v â€” the aame carelesn and uncalcula same conveyance beck m.o biâ€žid*,n i ting indifference aoout human life â€” char which caun 1 be d is rlad lung ifun excellent opp.,ii,,,,ii oil i . g nt u glance the various styles ull lboauty,fashi 11 dress tee which ure alll lu : deserving lo be no reed it strnckh ime very forcibly that 11 great in tny unit i ividuals appeared there with the b,.pe ll it .', ; admired and llu eonliast whs ii.itl i a int.lii ,, us bet ween tha su.irliin.h |. ir ,,,,â€ž,â€¢ 1 1 ut tricky dandy or dan-l i ' / tt aad ike stem and rigid features offl i tl.e piinsi'tigeis wbc were evidently the l lima nl'caie or ln cre cugerly benl i 11 the pursuits of gain i v.,,1 are uncoescioui ef the ijp'-e nf time lÂ»li,-n promenading in itrouduny t is so s||r-i..i molsn iiw.iy by tin


crowds of people nuiko every thing tnnrtj lively antl cheerful i was pleased with the beautiful iriinsp.iriiurie-s which i im-ii.-iu ui various places und with the ingenious contrivances which are resorted to lu act every thing oil to greater udvantase nol withstanding the opposing darkr.es j auw u i.uiuber of people moving in the di rection oltrutimort st v 6nd learned that it was to see the plamtariuin of mr kyle in which is exhibited a view of the greut comet that is expected .,, visit ua shortly as 1 hope to see this celefrtinl wonder in ho board aud i*p..n heavens 1 decline goihg to inspoct the artificial one inuuufao tured by mr kyle in pasmg ulotig i noticed a fiacre tho tup uf which was surmountedbritish government men io ' italic li wasiiii-.gti.il ; the rebel leader aa lh wus styled by mixing poison with hie lf,Â«.d ut n dinner party but was timely lunough discovered to be prevent i*ur hsuiug these reflections i found that i bad hu ii ,,',,â– , i el ue into thn park â€” it waa h'.tii . the crowds had disappeared from i limed erey uud u solitary watchman was l.-ulling -â€¢ pus iu o'clock from the silent ip.ir.ic al lho city hall it was then that larnumiie frum my reverie and pondering hen the manner iu which the day had lean hsprni that it hud pus-e.'amay in frivolous haiiiuionienl productive of mi solid udvan itag .'â– till sell â€” if uo good to nia.illi.hl.it - l


s then fur the first time thut i bngan it feel unhappy i felt sir a curious hs.'iis'iiii,u about the epigastric ri,.,, 3h pro assit.intl.m no t the fl the nlil-lib i h tariff to a mun i 1-h fnr in t ti..il i lh lie h the i stnlcs.h t h tin t"l ,,, â– ;. b . th bill ilie i int i elii-.t.b those iâ€ž i â€¢ i no .,, ' h h'ul.'h ih in i elude v liiir.l.b the to ihcuih tii,'h he benefit n those h our now to do â€¢ in ),| divided between hem con ih gross has the trouble tin > i number to in say the federal nion l ri l classes even un served â€” nol compulsion lÂ»lare if the imiitlier ol ihmc wh^i ofthe mississippi or to each individual of sake of amassing a few paltry pence nrc |â€ž ine that ansti ptts was a much wis.-^b them 500 dollars without an equivalent willing to see the union dissolved ? man than i ii l lus ' u i wss n betti ,â– ir the semhlsneu , if one in exchange what banner constitution philosopher in regard lo the tilings of ' '- h ever that these seven liuuilri-.l sugar ery day lift and that he experienced moroh planters pick tbe pockets of all the inhabit w . c . s ,, r ecli amos excellent rr Â«Â«â€¢ enjoyment in the parade l'a,-â€žurt aitt-ui'liiiscoun.p tu like manner&loa like vicw clf lho sp li was


publishsd.no than the grecian sage ever possessed inh extent ia perhaps none of our concern and , si ,â€ž ,.,â€ž new y ork - journal i the solitude l lus cave i cermiulv nu consolation to ns i will câ€žm.n-.ve in which the or u tits of it was in the midst of meditations !..*-â– make no calculation of what he amount the omtor wm6 apwn to be both unsound be that we were engaged in perusing nf plunder is my reader can easily do il .,â€ž,â€¢â€žâ€ž,â€žâ€ž,*,,â€ž.,,Â». 1 ia too long lor entire the ramwer that admirable pro â€ž.., n â€ž(â– if he is not already sick at the oootempla ,â€žâ€ž,.,.â€žâ€žâ€ž ;â€ž â€ž ur ,,;,,â€ž.,.. | llt , â€ž s lllt â€ž f the bntlrt n.oml.sl a-bonwet iiupon tl.eh tion uf such oppression thoroughly eon t |â€ž. pl ,. hh11 i lv a a g i humor with which l " !,,, "> "', *','** "'' '""- '' "â– ''"* i ' '*â– vinoed of the enormous injustice and folly ,. â– ' wriltci * we ,, ivo ,| 1u ii w i l;x - uni hundred years lh ught l had anp-h nfthe so called american system tracts ~ sed aiace that mtgbty p mate bad prov.h bo much mr editor for the tariff and mr ciay manifests great anxiety for Â«Â«â€¢ he vau.t of our hopes ot happineso,h sugar my readers must remember that ' ajldle^aetero butos.and thinks they "'"' ll "' 1 " l1 j 1 '*â„¢' * m ''" , ""


tunff tuteenmue Â»â€¢ abrtanual ibiaf of 1 table lhe xl-,,.1 ,â– l,u..rv iieoi.r s poet of lhe c nnv au olher was .,,' a 1 wrirnn â– *â€¢..-'-. a â€¢.Â«:,.... f ni liter for e sis . b .,â€ž. c lo > .-'â€¢ ii 11 ' urÂ»iu,'i pro hdlof liire.auduep^tod somewhat njd ijut i*se otiubip uÂ»nautuctct.iui lw*u bllt i i'r >'â– it ll 1 ' i i .â– : -,,' ; , .' ., ,,,,., ******* . ' , ,, ,!â– tt - *************'â– other advantage it became the weal hi n.g in and ro without nnv steady l n h e*t sn-it in america recently tin bttempl p so i.iviow â€” pleasure ni'iener ial.--s s l.y^^h i is beet mode lo frighten lhi â– â€¢< room lofollowing notice : â€¢â€¢ i p ,-,,...â– ,â– eiage^^b service in both fl respects at least a loner pwaa almoel salted with iiel they are lh eeirii nl mr clay and upon determination to take this opportunity < i l all the rei-.tgni ,.< cil ilities < i gentleman make an inspect iun nl a good many liwrll-h ly intercourse entitled to his kindness ings and of their inmates h tims up-h antl respect neither had given the cared accessible m spe tutors l,m tâ€ž,*l lightest cause for the rude attack which deterred from ii by in apprehension thai i waa made upon them both mr mj visions of hoppinesi might be jeopar i saiiliet is a blacksmith a man of sound diced at what i might observe


â€¢' i-ppi-ig^h facts nr arguments lie resorts to tho law here and there to lend some and iake.nl of a certain code in thai case made and ti.er travellers ou m return whilst i proi nl â€ž i ami ial â– lo abusing mr barchet walking in the neighborhood of park row i in e ihall leave him in the hands ,, i the my attention was railed in u vehicle sim-^h blacksmith upon ins anvil and under har lo the one i bad jusi h-l'i although i ilia hammer the iron ribe of the american not quits so handsome li was nark 1 1 systom will crock like the bones of a ml â€¢â€¢ n general uuios dry uock und i.i lhe jaws of n terrier ipon lhe wall st j^m whole matter we say il these are the l otairvi _- , number of pei_onsen-h manners ofthe american system ere are i . in , : ,,_ , _ .,.â€ž.,.,â– ,.â€žâ€ž.,. m j gb , ,,- holnt , fl still for tree importation of the foreign ..,â€ž.,.,>, ,,| (| ,.,., i n view eo without asking â– coinmoiliiy vxe beg that wherever we que ltlona i doterm dtojointhem â€¢'>.â– â– may go we may net be ehut up to the do soim ju1|d ,â€žâ€ž.â€ž,.*,,., advancing wards â– trjestic iniiiiiifai-ttire but mr clay la ve the eastern hide f tl mu ,,, a,â€ži i was i ry polite to the irish he saye : tjfall â€žâ€ž, lon , ,, learning that thn party wus


of the tii-onill sultan ni a pieoe ot parchment 1 -.. e-th knew b,l ue tha tb grand hiilluu utaili-h thu largest flourish 0 his name ol anyh ltti.it ll lie world when i desccndeilh ilr iu tins building broadway wore a lif-h l.'t-ren aspect rom ha i lmd seen beliue.h lit eras a porfcel picture l variety 11 nil i furnished me un excellent opp.,ii,,,,ii oil i . g nt u glance the various styles ull lboauty,fashi 11 dress tee which ure alll lu : deserving lo be no reed it strnckh ime very forcibly that 11 great in tny unit i ividuals appeared there with the b,.pe ll it .', ; admired and llu eonliast whs ii.itl i a int.lii ,, us bet ween tha su.irliin.h|. ir ,,,,â€ž,â€¢ 1 1 ut tricky dandy or dan-l i ' / tt aad ike stem and rigid features offl i tl.e piinsi'tigeis wbc were evidently the l lima nl'caie or ln cre cugerly benl i 11 the pursuits of gain i v.,,1 are uncoescioui ef the ijp'-e nf time lÂ»li,-n promenading in itrouduny t is so s||r-i..i molsn iiw.iy by tin objeets which it â– t year attention i waetnereforefiui it ti o'clock nl t i bad t en 1 i lhe city iii icl where i tn.ei.d to dine l'he i ... 1 hour ' looked upon asdecidodly the ibiippivst of all the twenty four ; it is in i nl e king of hours aad it is some itliiug |., -",â€¢;, i ng table


: for though 8 factitious majority in congress linve imposed them on us it is a notori ous truth that liis majority is composed of interests entirely diverse but coalesc ing in this particular instance to effnct certain purposes aud that even under this compact lu persons benefited are but a very small portion of thepenplo of these united suics i may then like honest (..', rge kremer cry aloud and spare not without comproinilting my republican prin ciples tl tariff is a subject whioh few profess to understand i spnak ofthe bu rls ofthe people and yet divested of its bard name uud the sundry mystifications winch its advocates have thrown around it i is a subject whicli every citizen how cu-r unlearned may us oasily comprehendAnime & The Video Game Industry!!!

Hey everyone! Check out my new video where I discuss the anime and video game industry about the possibility of more of the shows we love turning into video games and being released in the US. So enjoy & please subscribe!

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3 comments on “Anime & The Video Game Industry!!!”

This is a topic I wouldn’t mind chatting all day haha.
I actually agree with you. I feel like most of these anime games on the console are made for promotional reasons. Every time we play games like DBZ or Attack on Titan, our money and time are going to the companies and this is spreading attention to the anime. However, like you said, unlike Pokemon, these games doesn’t get much attention. The phone apps


Burea, CA, USA).

2.2. Design of the RPA Primers {#sec2dot2-foods-09-00278}
------------------------------

Based on the *nuc* gene (Genebank accession: EF529607.1) of *Staphylococcus aureus*, *toxR* gene (Genebank accession: GQ228073.1) of *Vibrio parahaemolyticus*, and *fimY* gene (Genebank accession: JQ665438.1) of *Salmonella enterica*, three sets of RPA primers were designed by using the software Primer Premier 5.0 (Premier Biosoft, San Francisco, CA, USA). The primers ([Table 2](#foods-09-00278-t002){ref-type="table"}) with target-specific labels were tagged with biotin and digoxin (primers for the *nuc* gene), carboxy fluorescein (FAM), and digoxin (primers for the *toxR* gene) or Cyanine 5 (Cy5) and digoxin (primers for the *fimY* gene). All primers were synthesized by Invitrogen Biotechnology Co. Ltd (Shanghai, China).

2.3. Multiplex RPA Reactions in Solution {#sec2dot3-foods-09-00278}
----------------------------------------

RPA was performed according to the manufacturer's instructions with a TwistAmp Basic Kit (TwistDX, Cambridge, UK). Briefly,[Figure 1](#foods-09-00278-f001){ref-type="fig"}. Firstly, multiplex RPA amplification was performed to generate amplification products of biotin-digoxin-, FAM-digoxin-, and Cy5-digoxin-tagged double-stranded DNA by using the labeled upstream primer and downstream primer. Then, the amplification solution was loaded onto the sample pad and diverted to the other end of the strip by capillary force. The labeled duplex DNA was combined with the anti-digoxin monoclonal antibody colloidal gold on the conjugate pad. Then, as the amplification solution continued migrating, the biotin-, FAM-, and Cy5-labeled duplex DNA was captured by the three test lines, respectively, where were contained with a corresponding anti-biotin monoclonal antibody, anti-FAM monoclonal antibody, and anti-Cy5 monoclonal antibody. The uncaptured gold particles flowed through. They were immobilized by the antibody on the control line. In the absence of the target DNA,


min, but the reaction time was longer. As a result, 10 min was the appropriate reaction time. The RPA assay was conducted under isothermal conditions between 30 and 50 °C. According to the results of strips and the test strip reader, the best reaction temperature of the LFD-RPA assay was 37 °C ([Figure 2](#foods-09-00278-f002){ref-type="fig"}c). Subsequently, seven magnesium ion concentration gradients of 0, 2.8, 5.6, 8.4, 11.2, 14, and 16.8 mM were tested. As shown in [Figure 2](#foods-09-00278-f002){ref-type="fig"}d, there were no obvious differences between the magnesium ion concentrations from 14 to 16.8 mM. Therefore, 14 mM magnesium acetate was found to provide an optimal performance for the LFD-RPA assay.

3.2. Sensitivity and Specificity of the Multiplex LFD-RPA Assay {#sec3dot2-foods-09-00278}
---------------------------------------------------------------

To assess the sensitivity of the multiplex LFD-RPA assay, 10-fold serial dilutionswere directly detected using the lateral flow dipstick, and the resulting visualization could be obtained within 5 min. To achieve triple detection, each of the upstream primers was labeled with biotin, FAM, and Cy5 at the 5′ end. All of the downstream primers were labeled with digoxin at the 5′ end. Three double-labeled detectable products were formed in amplification. Meanwhile, the lateral flow dipsticks with three test lines were prepared for RPA product detection. However, LFD is generally considered as a qualitative detection method due to the lack of results analysis apparatus. In this study, a test strip reader was used to analyze the results of the dipsticks. The reader (TSR-200) could scan the test strips and detect the intensity of the reflected light by using modern photoelectric


experienced learning and development professional. He brings a focus on e-Learning technical support, and a pharmacist's eye to the SkillsPlus International Inc. team. His expertise draws from his work in pharmacy education & training, emergency room clinical pharmacy services, home infusion pharmacy, team & organizational development/facilitation, computer programming, healthcare website development, and multi-year strategic planning. Austin has completed: a Bachelor of Science degree in Microbiology; a Doctor of Pharmacy (PharmD) degree from the University of California in San Francisco; and a post-graduate Hospital Pharmacy Residency from Duke University Medical Center.Q:

*** glibc detected *** free(): invalid pointer

I have the following code that produces a *** glibc detected *** free(): invalid pointer error whenever I run the code.
main.h:
#ifndef PTHREAD_CALC_H_
#define PTHREAD_CALC_H_

void* task(void*);

#endif

main.cxx:
#include <stdio.h>
#include <stdlib.h>
#include <sys/time.h>
#include <pthread.h>
#include "main.h"

int main(int argc, char* argv[]) {

    pthread_t *threads = (pthread_t*)malloc(sizeof(pthread_t)*2);
    double  *temp;

    double sum = 0.0;
    for (int j = 0; j < 2; j++) {
        pthread_create(&(threads[j]), NULL, task, NULL);
    }

    for (int j = 0; j < 2; j++) {
        pthread_join(threads[j], (void**)(&temp));
        sum += *temp;
    }

    free(threads);


campaign, a twitter-based initiative started in 2017 and continued in the year 2018 ([@B31]). It originated from a walking group in AlJouf region in northern Saudi Arabia and resonated into other major cities of the country. It aims to increase the number of people males and females who assume regular walking habit for the promotion of health and preventing of chronic disease. In its second year, the initiative get support from the Sports for All Federation. Now, there are more than 50 walking groups in many cities around the country joined this initiative and the number appears growing. In addition, a number of celebrities are also promoting this initiative, which may add momentum to it. Indeed, at some point of time the initiative hashtag reach a trend.

Saudi Arabiacan also be utilized to increase PA level of the patients.

Healthcare settings in Saudi Arabia can offer a unique opportunity for counseling young and old adults about PA and active living behaviors. However, a review study addressed PA counseling practice among physicians in primary health care centers in Saudi Arabia (with nearly 50 million yearly visits) concluded that there was a limited data available about PA counseling in primary health care providers ([@B61]). However, the opportunity and challenges are still there for much needed counseling, as a local study in south western Saudi Arabia revealed that the percentage of individuals attending health promotion clinics who consumed imbalanced diet and were inactive reached more than 90% of the sample ([@B62]). In addition, health care providers in Saudi Arabia, need


args=(),
        kwargs={'shortened_url': shortened_url}))

If it is method 2, you don't need the named parameter in the url pattern at all, can instead just reverse the url pattern and tack on the querystring parameter:
def makeurl(request):
    . . .
    url = reverse('create')
    url += '?shortened_url={}' + shortened_url
    return HttpResponseRedirect(url)

If it's method 3, you don't need the named parameter or a querystring value:
def makeurl(request):
    . . .
    request.session['shortened_url'] = shortened_url
    return HttpResponseRedirect(reverse('create'))

def create(request):
    shortened_url = request.session.get('shortened_url')
    . . .

    # delete the session value
    try:
       Island School of Design, she used to draw bears on the walls of her childhood bedroom outside Chicago. She has since gone on to paint giant fish at the Baltimore National Aquarium, Burrowing Owls at Facebook’s headquarters in Menlo Park, California, and bighorn sheep on the sides of a motel near California’s High Sierras. Her style is highly literal—there are almost no abstractions in her illustrated work.

Magnificent Frigatebird. Photo: Courtesy of Ink Dwell

Nonetheless, imitation can be challenging. The nine-foot Ostrich in the Cornell mural was a battle for Kim, and she had to work relentlessly to hone the subtle yellow streaks under the Cassowary’s bill. But the hardest part of the project, Kim says, was spending so much time inside (the lab does have a sound system that


drinking alcohol, using drugs, addiction to sex, and overeating, excessive use of TV or computer leads to various ailments. But if you compare, attachment of animals is limited to food for their survival and to safety of their offspring. On the contrary, human beings are attached to worldly possessions. Some have attachment for variety of expensive cars and some are attached to ornaments or fashion accessories. There are people attached to various relationships and some are clinging to host of negative habits. Over attachment of people with money and worldly possessions is leading to various negativeness in society.

Greed:

Human being is a highly greedy species. Animals’ greed is limited to gathering food for now. They do not hoard food even for their next meal. However for human being, theirTo develop selflessness, you will develop habits of generosity, helping others, compassion, justice, righteousness and love. You will realize the power of gentle touch, a kind word, a listening ear, a pleasing smile, an honest compliment and a helping hand. These newly acquired habits are capable of bringing happiness in lives of many people around you. Reaching out to someone with gentle caring and sensitivity is a noble act of selflessness. You are not doing it for a profit or selfish gains. This act also helps you overcoming your pride and inflating your ego.

Till date, you were living in a fool’s paradise of self ego. Your vision is now expanding. In selflessness, you will be joyful with the accomplishments of others and in their happiness. You would now


    }
        }
        $page = $pages[$pageIndex];
        return $this->baseLocation() . "/page_{$page}.php";
    }

    /**
     * @param        string $page
     * @param int    $status
     * @param string $message
     *
     * @return void
     */
    public function redirectToPage($page, $status = 303, $message = 'See other')
    {
        $location = $this->pageURI($page);
        $protofield is used to uniquely identify the user’s machine to Steam, for SteamGuard. Capturing an account_name, password or login_key, and sentry file hash is equivalent to gaining access to the account.

But, alas, we can only modify things- not read them. Unless there’s something silly like a padding oracle attack in play… … Oh boy.

Was Steam really vulnerable to a padding oracle attack? There was a simple test: I took a copy of PySteamKit (the real SteamKit is a .NET program, and I didn’t want to mess with Mono), and patched its encryption routines to either generate correctly-padded garbage data or incorrectly-padded garbage data when a flag was set. Then, I just connected to Steam normally with this patched PySteamKit, set either one flag or the other immediately before


closed, I could just restart it. I could even run the attack in parallel, between all Steam servers, massively speeding it up.

I started by implementing my own toy Steam client, one just smart enough to go through the initial handshaking and establishment of session keys. Then I could just send ciphertexts and tell whether their padding was valid or not.

I modified my PoC to parse a PCAP and pull out the ChannelEncryptResponse, and the encrypted messages sent afterwards- those are the ones I wanted to decrypt. The big target was, of course, the CMsgClientLogon and the secrets it contained.

Then I received an email from Valve-

In terms of mitigation we are going to take a two stage approach. First, we are fixing the server code to not respond to(1). Smad6 and Smad7 are characterized by the stable interactions formed with both activated TGF-β and BMP type I receptors, thereby preventing phosphorylation of ligand-induced Smads (4,5). In addition, Smad6 has also been demonstrated to interact with phosphorylated Smad1 to prevent the formation of an active signaling complex of Smad1 and Smad4, preferentially inhibiting the signaling pathways activated by bone morphogenetic proteins (7,16). Furthermore, it was previously demonstrated that Smad1 interacts with Hoxc-8 in response to BMP stimulation (13). Hoxc-8 functions as a transcriptional repressor. The interaction of Smad1 with Hoxc-8 dislodges Hoxc-8 binding from its element, thereby resulting in initiation of gene transcription (13).
In vertebrates, there are 39 Hox homeobox-containing transcription factor genes, organized into four separate chromosome clusters, which play critical roles in the process and


The optical art has provided many varieties of spectacles of the every-day type (for reading or distant viewing), industrial safety eyewear, soft plastic safety goggles (for use with power tools), ski and motorcycle goggles, swimming and underwater diving goggles. The every-day type of spectacle is designed to provide the wearer with corrective lenses for his eyes and usually the spectacle is not worn to obtain the protection provided by the other types of eyewear mentioned. The corrective spectacles and the types of goggles mentioned have developed largely independently, and at the present time a person desiring a corrective spectacle, a corrective safety goggle and corrective swimming and diving goggles has little choice but to purchase each type separately. Safety goggles, ski and motorcycle goggles may be purchased towould cut back branches and trunks, using the wood to heat their homes, and rake up leaf litter from the forest floor. In the early 1900s, chestnuts were a major food source for approximately half a million people in Italy, Mathews said.

This photo shows the view from the Monti Pisani in February 2014, looking north toward the Apuan Alps. Andrew Mathews

But as the region became more urbanized and industrialized over time, diets and lifestyles changed. Eventually, many chestnut forests throughout Italy—including the one Mathews was walking through in 2014—were abandoned.

That afternoon in the Monti Pisani, Mathews was with Massimiliano Giambastiani, an Italian biologist who studies cultivated chestnut varieties, and Alessandra del Chiaro, who runs a farm located farther down the mountain that produces olive oil, wine, and chestnuts.


that were important to people in the region—and to determine whether or not those issues could help residents “make sense of climate change.”

This map details fatal floods and landslides in Italy from 1965 to 2014. Salvati et al./Science of the Total Environment

At first glance, the concerns of tending to trees and maintaining riverbeds may seem far removed from climate change. Indeed, for many of the rural people he spoke with in the region between the industrialized cities of Lucca and Pisa, Mathews found that “climate change is not a very useful concept.” However, “it’s entirely normal and reasonable that people should deal with climate through the environmental phenomena they care about,” he said. And in a region where mudslides and floods are not uncommon, people—from farmers to loggersOverview: membrane traffic in multicellular systems: more than just a housekeeper.
Membrane traffic is a fundamental cellular function by which molecules are transported between organelles in the post-Golgi network. Accumulating evidence supports the notion that membrane traffic is not only indispensable for normal cellular function and maintenance of cellular viability by playing housekeeping roles, but also critical for various functions characteristic of multicellular organisms. This Minireview series will focus on the latter aspects of membrane traffic. The topics discussed are: the pathophysiological impact of clathrin-associated adaptor protein (AP) complexes, the significance of membrane traffic in Alzheimer's disease, regulated exocytosis of insulin, secretory lysosomes in immune response, exosomes in physiology and pathology, viral and mammalian ubiquitin ligases modulating immune response, membrane traffic of bacterial toxins, and containment of bacterial infection


       "given directory %s" % ckpt_dir_or_file)
  return pywrap_tensorflow.NewCheckpointReader(filename)

def load_variable(ckpt_dir_or_file, name):
  """Returns the tensor value of the given variable in the checkpoint.

  Args:
    ckpt_dir_or_file: Directory with checkpoints file or path to checkpoint.
    name: Name of the variable to return.

  Returns:
    A numpy `ndarray` with a copy of the value of this variable.
  """
  # TODO(b/29227106): Fix this in the right place and remove this.
  if name.endswith(":0"):
    name = name[:-2]
  reader = load_checkpoint(ckpt_dir_or_file)
  return reader.get_tensor(name)

def list_variables(ckpt_dir_or_file):
  """Returns list of all variables in the checkpoint.

  Args:
    ckpt_dir_or_file: Directory with checkpoints file or path to checkpoint.

  Returns:
  of thirty days.'  Thus GMS and RKO were on notice that the Commission's grant of approval was subject to further administrative proceedings.  The statute provides that where a protestant is found by the Commission to be a party in interest and to have specified 'with particularity the facts relied upon * * * as showing that the grant was improperly made or would otherwise not be in the public interest' the Commission shall within 30 days designate the application for hearing or oral argument.  And 'pending hearing and decision the effective date of the Commission's action * * * shall be postponed to the effective date of the Commission's decision after hearing * * * unless the Commission affirmatively finds for reasons set forth in


number of tools that you can use, including a map. This will help you to pin point exactly where you will be staying and it will show you the accommodation facilities that are closest to where you will be. Regardless of the reason for your visit to Stellenbosch, we can guarantee that you will find the type of accommodation you are looking for.

What information can you find on this website?

Reviews are vital these days when it comes to finding safe, reliable accommodation. Knowing what to expect can help to ease your decision making. For each accommodation facility listed on this website, you will find reviews and ratings.

But reviews for Stellenbosch accommodation is not the only information you will find.

Regardless of where you are staying, we feature Stellenbosch accommodationthe terms, and b) a reliable payment mechanism was available to compensate the creator for their work. Unfortunately the only way to implement "a" today is through DRM, and I have yet to see any mechanism for "b" that will work with re-selling content except to rely on the honor system.

There's nothing to stop bands from distributing their own stuff free unless they've signed a contract that states otherwise. But the existance of MP3.COM (before it got sold off) and now "GarageBand.com" shows that this works. Many creatives types are finding ways around the RIAA system, and I think that's great. I think writers have a golden opportunity too; but for things like Television and Movies it gets more problematic, because even a cheap movie can still be


an interesting take

>>>However, the pertinent question may become "Isn't it great that the digital world allows us to duplicate things at minimal cost?

Yes it is great!!!! Its not just great its awesome!

>>>Why stem it?". Sure. Why stem it? Why not duplicate all the contents and share the love around? Well, in some parts of the world, that's called communism.

I’ m not sure which parts of the world or which version of communism you are talking about :P

>>Ok, don't laugh.

Couldn’t help it!

>>>If it were possible, then we could all open source and start fabbing cars and houses and all the stuffs that we all need.

I think there are pretty fundamental laws of the universe, like the special theory of relativity, the uncertainty principle that mean that the duplication ofto the people around you, give the best of yourself in everything you do and see that everything will be much better.” Category :good morning phrases

– “You can take advantage of this day to express your love, to call that special someone or to forgive. The important thing is to live intensely every moment and not let the important for later. “ Category :good morning phrases

We know these phrases to start the day with enthusiasm will please your loved ones.

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Content delivery network and streaming media provider StreamGuys, Inc. and Haivision Network Video, the leader in live video transcoding, have struck a partnership to offer complete live video asset management and streaming services to their customers, from broadcasters to enterprise-level businesses.

Haivision’s KulaByte product line offers cloud- and server-based live transcoding solutions that allow StreamGuys to deliver a single live video source to many customers and devices at multiple bitrates, formats and resolutions. The KulaByte transcoding technology improves StreamGuys’ workflows by combining live transcoding with the flexibility of targeting specific streams for devices using HTTP Live Streaming (HLS), RTMP, RTSP, MPEG-TS, and Smooth Streaming.

StreamGuys’ virtualized, adaptive bitrate streaming service on the server side delivers the most appropriate bitrate to each device based on current network conditions — ensuring the1887 Nunhead is recorded as having a population of 10,727. There was a Nunhead Football Club from 1888 to 1949. Nunhead has some fine examples of late Victorian / early Edwardian properties; these can be seen on both Carden Road and Tresco Road. It is even reputed, in Claire Tomlin's biography of Charles Dickens' mistress Nelly Ternan, that Charles Dickens was taken on his death bed from the house he rented for Ternan, at Windsor Lodge in Linden Grove to Gad's Hill to die. The house no longers stands, but was at 31 Linden Grove. Old maps show that the church was next door to where the dental surgery now stands at 42 Linden Grove, so Windsor Lodge was presumably more or less opposite that.

Regeneration
Nunhead forms part of


Children of the Corn (1984 film)

Children of the Corn (advertised as Stephen King's Children of the Corn) is a 1984 American supernatural folk horror film based upon Stephen King’s 1977 short story of the same name. Directed by Fritz Kiersch, the film's cast consists of Peter Horton, Linda Hamilton, John Franklin, Courtney Gains, Robby Kiger, Anne Marie McEvoy, Julie Maddalena, and R. G. Armstrong. Set in the fictitious rural town of Gatlin, Nebraska, the film tells the story of a malevolent entity referred to as "He Who Walks Behind the Rows" which entices the town's children to ritually murder all the town's adults, and a couple driving across the country, to ensure a successful corn harvest.

King wrote the original draft of the screenplay, which focused more on thethe cornfields and indoctrinates them into a religious cult based around a bloodthirsty deity called “He Who Walks Behind the Rows”. Isaac and his subordinate, 18-year-old Malachi, lead the children in a revolution, murdering all of the adults (ages 19 and up, since 18-year-olds are seen as halfway between teenager and adult) in town as human sacrifices. Only Job and his sister Sarah, are not involved, as Sarah was sick and Job was not allowed to attend the meetings in the corn with the other children. It is revealed in the opening credits that Sarah has visions, which are portrayed through the credits via drawings.

Three years later, on October 31, 1983, Vicky and her boyfriend Burt travel through rural Nebraska on their way to Seattle, where Burt will


Effects of combined knee loadings on posterior cruciate ligament force generation.
Resultant forces in the posterior cruciate ligament were measured under paired combinations of posterior tibial force, internal and external tibial torque, and varus and valgus moment. The force generated in the ligament from a straight 100 N posterior tibial force was highly sensitive to the angle of knee flexion. For example, at 90 degrees of flexion the mean resultant force in the posterior cruciate ligament was 112% of the applied posterior tibial force, whereas at 0 degree, only 16% of the applied posterior force was measured in the ligament. When the tibia was preloaded by 10 Nm of external torque, only 9-13% of the 100 N posterior tibial force was transmitted to the posterior cruciate ligament at flexionangles less than 60 degrees; at 90 degrees of flexion, 61% was carried by the ligament. This "off-loading" of the posterior cruciate ligament also occurred when the tibia was preloaded by 10 Nm of internal torque, but only at knee flexion angles between 20 and 40 degrees. The addition of 10 Nm of valgus moment to a knee loaded by a 100 N posterior tibial force increased the mean force in the posterior cruciate ligament at all flexion angles except hyperextension; this represents a common and potentially dangerous loading combination. The addition of 10 Nm of varus moment to a knee loaded by a 100 N posterior tibial force decreased the mean force in the ligament between 10 and 70 degrees of flexion. External tibial torque (alone or


l composite?
True
Let d(r) be the second derivative of r**5/20 - 5*r**4/12 - 2*r**3/3 - 5*r**2/2 + 3*r. Is d(6) a prime number?
True
Let c(x) be the first derivative of 13*x + 0*x**2 - 1/3*x**3 - 1. Is c(0) composite?
False
Suppose 0*f - 4 = -3*f - 5*s, -1 = -2*f - 5*s. Is (((-654)/f)/(-1))/2 composite?
False
Let v be (2/2)/(2/(-52)). Let d = v + 48. Is d composite?
True
Let a(b) = 4*b**2 + 14*b + 13. Is a(20) a composite number?
True
Let a(q) = q**2 - q - 7. Let v = 6 - 3. Suppose b = 5*s - 25 - 4, -4*b = -v*s + 14. Is a(s) a prime number?
True
Suppose -1885 = 13*z - 18*z. Is z composite?
True
Let a = 5 + -1. Suppose 4*d = 4*b + 32, a*d5*p - p = 0. Is f(p) a prime number?
True
Let n(h) = 23*h + 1. Let i be n(2). Suppose 0*o = 3*o + 63. Let g = o + i. Is g prime?
False
Suppose -72 = -3*p - 24. Suppose 2*s - p = -0. Let y = s - -25. Is y composite?
True
Suppose -5*v + 3 = -4*v. Suppose -d = v*d - 12. Is d*1/((-3)/(-47)) prime?
True
Suppose -1665 = -5*s - 550. Is s composite?
False
Let d be ((-10)/(-3))/((-8)/(-132)). Suppose -6 = 4*l - 2*l, -4*l + d = x. Is x prime?
True
Let p(g) = 4*g**2 + 3*g + 4. Suppose 2*k + 8 = 4*o, 3*o - 2*k = 7*o. Let x(j) = -2*j**2 - 2*j + 1. Let s be x(o). Is p(s) prime?
True
Suppose 0 =


tag:blogger.com,1999:blog-67927106717334455932018-03-02T09:21:53.938-08:00Summer of GödelDavid Furcyhttp://www.blogger.com/profile/12284114397975852146noreply@blogger.comBlogger23125tag:blogger.com,1999:blog-6792710671733445593.post-21172722278909262072014-12-31T12:34:00.000-08:002014-12-31T12:34:10.232-08:00Almost all integers contain the digit 3This is my last chance to blog this year. However, I did not get back into the proof of Gödel's incompleteness theorem yet. So instead, this post is motivated by this Numberphile video, which explains why almost all integers contain the digit 3. More precisely, the percentage of integers that contain at least one occurrence of the digit '3' in the set \(\mathbb{N}_u = \{0,1,2,3,\cdots,u-1\}\) goes to 100% as the upper bound \(u\) goes to infinity.

We are going to attack this problem with two different approaches. First, we'll use a recurrence relation approach. Second, we'll go over the combinatorial proof discussed in the video. Finally, we'll check that the two approaches do give the same answer.

which does contain an unbounded existential quantifier. The only reasoning I could come up with to resolve this difficulty is that, to determine the truth value of σ ≤ τ, one only needs to check a finite number of addition facts, because the value of v that works, if it exists, must be less than or equal to the numerical value of τ (which must be a constant number for the truth value of the whole formula to be defined).

Now, let's consider the following wff:

∀x ( (e(x) ∧ 4 ≤ x) → (∃y ≤ x) (∃z ≤ x) (p(y) ∧ p(z) ∧ y + z = x) )

The interpretation of this open wff is "Every even number greater than 2 is the sum of two primes,"


we come to the main result of this post:

Theorem: Q is Σ1-complete.

Proof sketch:

Q correctly decides every atomic Δ0 sentence: these sentences are either closed equalities or closed inequalities; the first case is already covered in our proof that BA correctly decides all sentences in LB; the second case also works out because each inequality between terms can be reduced to an inequality between numerals (since each closed term can be reduced to a numeral SSS...S0), which in turn is correctly decided, because Q captures the ≤ relation.

Q correctly decides every Δ0 sentence: we can again use structural induction here

Q proves every true Σ1 sentence: since each true bounded kernel (that is, every true Δ0 sentence) is proved by Q, every trueformal theory.

Proof sketch of part 1:

Assume that m ≤ n

There must exist a natural number k such that: k + m = n

Since Q can prove everything that BA proves, and BA can prove all true equations, we have: Q ⊢ k + m = n

By existential generalization (an inference rule also called 'existential quantifier introduction'), we have: Q ⊢ ∃x (x + m = n)

Now, here are axioms of Q that we will need in the second part of the proof:

Axiom 1: ∀x (0 ≠ Sx)

Axiom 2: ∀x∀y (Sx = Sy


alternative interpretation used in Smith's proof is an extension of IA with two new elements a and b in the domain such that a is its own successor, b is its own successor, and addition and multiplication are extended in such a way that 0 + a is equal to b and 0 + b is equal to a, thereby falsifying φ.)

Q cannot derive ¬ φ:

This is because Q is sound and ¬ φ is false under the original interpretation IA.

So this chapter contains yet another proof of incompleteness that is much simpler than Gödel's proof.

Since φ represents a trivial fact about addition that Q cannot prove, it must be the case that Q is a weak theory of arithmetic.

Nevertheless, Q is interesting because Smith promises to prove (in a future chapter) that Q is sufficiently strong. Recall that this propertyquantifier. Let ∃x R(x,n) be a sentence of L that expresses "there exists a number x such that R(x,n) holds."

In short: n ∈ K if and only if ∃x R(x,n) is true in L's interpretation.

That is: n ∉ K if and only if ¬ ∃x R(x,n) is true in L's interpretation.

If the set of true sentences of L were effectively enumerable, then we could go through and, for each formula of the form ¬ ∃x R(x,n), we could output the value of n (while skipping all of the other sentences). But this algorithm would constitute an effective


express a property (or relation) but its axioms and inference rules may not be strong enough to capture it, that is, to prove it (even case by case).

However, if T is a sound AFT and T captures P with the wff φ(x), then φ(x) does express P, since, in a sound theory, every theorem is true in its own interpretation.

David Furcyhttp://www.blogger.com/profile/12284114397975852146noreply@blogger.com0http://summerofgodel.blogspot.com/2013/06/capturing-numerical-properties-in.htmltag:blogger.com,1999:blog-6792710671733445593.post-89853631516321668232013-06-21T15:32:00.001-07:002013-06-21T15:32:44.715-07:00Formal systems or axiomatized formal theoriesIn chapter 3, Peter Smith defines formal systems or, as he calls them, axiomatized formal theories (I will use AFT as an abbreviation for this phrase).

A theory T is an AFT if...

T is couched in an interpreted formal language, that is, a formal language L of well-formed formulas (wff's) that are meaningless sequences of symbols,part 4 of the definition of AFT above). The difference is akin to the difference between being able to discover a proof and being able to check a known proof.

T decides w if either T ⊦ w or T ⊦ ¬w.

T correctly decides w if T ⊦ w whenever w is true and  T ⊦ ¬w whenever w is false according to I.

T is negation-complete if T decides every sentence (i.e., wff with no free variables) in L. Recall the distinction between negation completeness and semantic completeness.

T is consistent if there is no sentence w such that T ⊦ w and T ⊦ ¬w.

Let's emphasize the difference between decidability and negation-completeness.

An AFT is negation-complete if its proof system and axioms are powerful enough to prove or disprove any wff of its language.

An AFT is decidable


not a theorem).

The last part of Chapter 3 proves important properties of AFTs, namely:

The set of wff's of any AFT is effectively enumerable.

The set of sentences of any AFT is effectively enumerable.

The set of proofs of any AFT is effectively enumerable.

The set of theorems of any AFT is effectively enumerable.

In general, effective decidability is a stronger property than effective enumerability. Being able to enumerate the theorems of an AFT does NOT imply that the AFT is decidable. Even if we are able to list all of the theorems, determining that a wff is not a theorem may require going through the whole list of theorems, which is often infinite. Therefore, this approach is not an algorithm: it does not always terminate in a finite number ofattention to Peter Smith's book on the proof of Gödel's incompleteness theorems (by the way, I own the first edition of his book; so that is the one I will be referring to). I did not expect to spend that much time on Nagel and Newman's book. But it was worthwhile in getting the big picture.

Chapter 1 is an introductory and user-friendly discussion of topics that were mentioned in earlier posts, such as basic arithmetic, formal systems, (in)completeness, consistency, the statement of Gödel's incompleteness theorems and some of their implications. Therefore, in this post, I will just highlight the points where Smith provides new information or has a different perspective.

Smith makes the distinction between proving a theorem and deriving a


arithmetic cannot prove its own consistency.

According to Nagel and Newman, a proof of the first theorem can be sketched in 4 steps:

Step 1: Build a wff (call it G) in the formal system F such that the meta-mathematical interpretation of G is: "G is not provable in F."

Step 2: Show that: "G is provable in F" if and only if "¬ G is provable in F." In other words, either both G and ¬ G are provable in F or neither one of them is. Therefore, if F is consistent, then neither G nor ¬ G is provable in F.

Step 3: Show (using meta-mathematicalmapping from the set of meta-mathematical statements to the set of mathematical (and more precisely arithmetical) statements in the formal system F.

This mapping is important because it means that proving any meta-mathematical statement about the structural properties of formulas can be reduced to proving wff's within the formal system F. In other words, this mapping reduces meta-level reasoning to reasoning within the formal system.

So, coming back to our example, proving that some formula w is universally quantified reduces to proving in F the wff that represents the statement (b) above.

Furthermore, this mapping established by Gödel is not limited to reducing structural properties of wff's to numerical properties (of Gödel numbers). It extends to relationships among two or more wff's.

So Gödel proved that


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In conclusion, we have described Gödel's arithmetization of meta-mathematics, that is, a mapping from the set of meta-mathematical statements about the structural properties of wff's in F to the set of wff's in F, where F is a formal system for arithmetic.

In particular, we have highlighted the two following structural relationships:

the structural relationship between a wff w and a formal proof of w

the structural relationship between a wff w and the wff resulting from substituting in w a numerical expression for a free numerical variable

resulting in the following two associations:

meta-mathematical statement	⇔	mathematical proposition in F

the sequence s is a proof of w

	⇔

	ProofOf( Φ(s) , Φ(w) )

meta-mathematical numerical expression	⇔	mathematical/numerical variable in F

the Gödel number of the wff
obtained by substituting n for
the free variable x in the wff w	⇔	Sub( n , 17 , Φ(w) )

David Furcyhttp://www.blogger.com/profile/12284114397975852146noreply@blogger.com0http://summerofgodel.blogspot.com/2013/06/mappings-and-arithmetization-of-meta.htmltag:blogger.com,1999:blog-6792710671733445593.post-60111159540554728452013-06-06T09:17:00.002-07:002013-06-06T09:21:28.527-07:00Mappings and Gödel numberingSection VI of Nagel and Newman's book describes mappings. A mapping is an operation that applies to two sets called the domain and the co-domain. More specifically, a mapping associates to each element of the domain one or more elements of the co-domain.

I found the examples of mappings in this section underwhelming. For example, the book discusses the so-called <span class="Apple-style-span" style="color:


mapping to complete his famous proof.

But we are not there yet. This post has only explained the Gödel numbering scheme. This is all there is to it! Sure, the numbers get large. But that does not matter, since we are not going to compute their values. We just need to know that the mapping exists.

However, there is one important property of this mapping that I have not mentioned yet. Recall that, in general, a mapping assigns to each element of the domain one or more elements of the co-domain. In this case, the mapping is really a function, since it assigns to each element of the domain exactly one element of the co-domain.  But, more importantly, Gödel's function is injective.

In an injective (or one-to-one) function,margin-left: 0px; margin-right: 0px; margin-top: 0px;">

To prove this meta-theorem about the set of theorems of FSN, we must reason outside of the system. More specifically, we can write a proof by structural induction. In other words, we can analyze the structure of the axiom and inference rules to prove that all theorems generated by any one of them has the property stated in MT1.

<br


to completely forget about it.

The only guaranteed way to make logically valid inferences, that is, 100% error-free symbol manipulations, is to empty one's mind of any interpretation of the symbols that could lead to implicit presuppositions, bias, or misguided intuition, in other words, to act like a mechanical automaton or a digital electronic computer.

Now, remember, we gave up the need for truth and meaning. But for the whole edifice to stand up to logical scrutiny, the formal system must still be consistent.

In the next few posts, we will look at several ways of demonstrating the consistency of an axiomatic system.

David Furcyhttp://www.blogger.com/profile/12284114397975852146noreply@blogger.com0http://summerofgodel.blogspot.com/2013/05/consistency-of-axiomatic-systems.htmltag:blogger.com,1999:blog-6792710671733445593.post-46083547870830631252013-05-17T18:00:00.000-07:002013-06-01T10:25:40.980-07:00Formal systems, axioms, inference rules, formal proofsI'll start this post bydescribing a simple formal system that I made up.

A formal system is comprised of axioms and inference rules. Each axiom and inference rule is defined syntactically, that is, by ordered sequences of symbols that follow strict syntactic rules but do not (necessarily) have any meaning. The set of all symbols allowed in a formal system are explicitly listed in its alphabet, simply, a finite, non-empty set of symbols.

My formal system, let's call it FS,  uses the alphabet {E,0,1} and has only one axiom and two inference rules. Here is the axiom (in the box below):
<div style="margin-bottom: 0px;


class="Apple-style-span" style="-webkit-border-horizontal-spacing: 2px; -webkit-border-vertical-spacing: 2px;">
Let's illustrate this point with several applications of the rules [IR1] and [IR2] in FS.

Assume that we start the process with an empty set of theorems, denoted by { }.

At this point, neither [IR1] nor [IR2] can be applied because we have not yet proved any theorems, let alone any theorems that match the form of their premise. However, we do have an axiom to kick start the theorem proving process. Indeed, axiom [A1] proves the theorem E0.

After this first proof, our set of theorems is as follows: { E0 }

Now that our settextbooks on formal logic, which were neither concise nor user-friendly. I still did not understand the proof.

Finally, a couple of years ago, I came across a promising volume: "Introduction to Gödel’s Theorems" by Peter Smith. I read the first few chapters but then ran out of time (and motivation) to finish it. The following year, I made another attempt: I had to start from scratch and did not get any farther into it the second time around...

So what is it going to take for me to understand the proof of GIT? Maybe a blog... I know that sounds weird. So I'll try to explain.

Now that I have a nearly-four-month-long summer ahead of me with no teaching


Q:

TimeSpan.Parse in VB.net to USA English Format

I want to parse any time format to an english usa format.
Please help
thank you
Jp

A:

I found a way is to use cultureInfo and i was able to solve it

-814,7 +814,7 @@ int genphy_update_link(struct phy_device
 		return status;

 	if ((status & BMSR_LSTATUS) == 0)
-		phydev->link = 0;
+		phydev->link = 1;
 	else
 		phydev->link = 1;


of a candidate copper wire pair in the cross-box. In the case where the serving terminal is located on a telephone pole, the technician then climbs up the telephone pole to the serving terminal to monitor the copper wire pairs using a probe or a handset to identify which copper wire pair is carrying the tone signal applied to the wire pair at the cross-box. If the technician cannot identify the wire pairs at the serving terminal, he must climb down the telephone pole go back to the cross-box and connect the tone generator to another candidate copper wire pair and return to the serving terminal and again trace which wire pair is carrying the tone signal. This process is repeated with due diligence until the technician identifiesLondon, where son Deji and daughter Lily also reside.

References

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