were considered significant.

Results {#jcmm13254-sec-0016}
=======

CD11b blockage or deficiency decreased osteoclastogenesis {#jcmm13254-sec-0017}
---------------------------------------------------------

The number of TRAP‐positive cells neutralized by anti‐CD11b antibody was significantly lower than control and anti‐CD18 antibody group (Fig. [1](#jcmm13254-fig-0001){ref-type="fig"}A and D). *Itgam* mRNA levels were down‐regulated in lentivirus‐infected cells (Fig. [1](#jcmm13254-fig-0001){ref-type="fig"}C). The group infected with lentivirus contained a lower number of TRAP‐positive cells than mock group (Fig. [1](#jcmm13254-fig-0001){ref-type="fig"}B and D). However, no significant difference was observed between the groups treated with anti‐CD18 antibody and IgG2a (Fig. [1](#jcmm13254-fig-0001){ref-type="fig"}D).

![CD11b blockage or deficiency reduced the number of TRAP‐positive cells, while CD18 neutralization did not have the same effect. Mouse OCPs were treated with sRANKL (100 ng/ml) for 7 days. (**A** and **B**) TRAP staining. Red arrows refer to TRAP‐positive osteoclasts. (**C**) Relative expression levels of *Itgam* mRNA, *n* = 3. (**D**)It will take care of the ceremony needed to wrap the code into a class, compile it and retrieve the result.

Dynamic compilation is an awesome feature to add to your projects. Especially frameworks will benefit from the compilation of dynamic expressions and scripts. There are two main ways of doing it: the Code DOM Compiler or the Roslyn project. In this blog I will show how to implement them both.

Need to add named event support to your class? Implement the IEventHandling interface or extend from the abstract EventHandlingBase class. In this tutorial I explore how you can give your class named events.


District of California
                   William H. Orrick III, District Judge, Presiding

                            Submitted January 20, 2016**

Before:        CANBY, TASHIMA, and NGUYEN, Circuit Judges.

      Morris S. and Shawn R. Maxwell appeal pro se from the district court’s

order declaring them vexatious litigants and imposing pre-filing restrictions. We

have jurisdiction under 28 U.S.C. § 1291. We review for an abuse of discretion.

          *
      Interview with Roman Novikov - CTO at TemplateMonster

TemplateMonster has been around since 2002 and is now one of the world's most famous template providers. Today we have a special guest. Meet Roman Novikov, Chief of Software Development Department and CTO at TemplateMonster.

Roman started programming at the age of 11 when his parents presented him his first computer as a New Year's gift. Since then, he hasn't stopped progressing and developing in this area.

In this interview, we ask Roman 10 questions around the topics of web performance, theme development, and more. Check out his answers below to get more insight into what his thoughts are on the subject.

Question 1: When building themes, what are some important aspects to keep in mind to ensure they are optimized for speed?

It is


important not to limit yourself to only one metric or tool. Always choose several of them to rely on. And you should always remember about speed for real users, not synthetic tests. You can always check your website's speed using an online tool like Pingdom.

Question 2: In your opinion, how important is website speed performance?

There are two aspects that really matter for a website: speed and conversion. It is hard to decide between them. They are both important but in different dimensions. They both score 12 points out of 10 in the list of most essential things for a website.

Question 3: What of some use-case examples of where it might be beneficial to sacrifice a bit of speed in return for features?

As you know, a customer may go \usepackage{amsbsy}
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The $\documentclass[12pt]{minimal}
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                \begin{document}$(p,q)$\end{document}$-*Bernstein polynomials satisfy the following first order* $\documentclass[12pt]{minimal}
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Theorem 3.1 {#FPar5}
-----------

*The* $\documentclass[12pt]{minimal}
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    $$\end{document}$$

Proof {#FPar6}
-----

In order to obtain the result we shall apply the so-called Navima algorithm (see *e.g.* \[[@CR19], [@CR20]\] and the references therein) for solving connection problems. If we apply the first order linear operator $\documentclass[12pt]{minimal}
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                \begin{document}$(p,q)$\end{document}$-Jacobi polynomials ([13](#Equ13){ref-type=""}) we have $$\documentclass[12pt]{minimal}
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polynomials. For our purposes some auxiliary results both for $\documentclass[12pt]{minimal}
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   The anterior pituitary gonadotropins, Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH), have complex chemical structures because they are glycoproteins and because they are composed of a common alpha subunit as well as a hormone-specific beta subunit. Our laboratory has demonstrated that there is large molecular weight LH-like substance as well as heterologous subunit populations intracellularly and that a heterologous population of LH alpha subunits are released. It is likely that these molecular forms of the gonadotropins are related to their biosynthesis. In order to better understand the biosynthesis of these hormones, it is proposed to further define the molecular forms of LH and FSH involved in biosynthesis, to develop approaches to separate these molecular forms and to characterize them. Once this is accomplished, experiments will be performed to


Let r(s) = 7*s**2 + 21*s - 27. Let i(t) = 13*d(t) - 6*r(t). Is i(-5) composite?
False
Suppose -2*u + 81 + 45 = 3*z, 0 = -5*u + 5*z + 365. Is u a prime number?
False
Suppose 3*k - 3 - 6 = 0. Suppose -4*o - k*c - 184 = 0, -1 = 3*c + 11. Is (-1 + 0)*(o + 8) composite?
True
Let q(j) = -76*j - 13. Is q(-7) composite?
True
Let f(k) = 19*k**2 - 5*k + 17. Let o(l) = -l**2 + 3*l + 45. Let h be o(8). Is f(h) prime?
True
Let i = 79 + -63. Suppose 0 = 21*g - i*g - 395. Is g prime?
True
Suppose -4*t = 5*p + t + 505, -5*p - 506 = 4*t. Is p/(-4)*(-12)/(-9) composite?
True
Let i(m) = -7*m -o = -254 + c. Is o composite?
False
Suppose k - 3122 - 423 = 0. Is k a prime number?
False
Let t = 21 + -9. Is 2/t - (-8943)/18 prime?
False
Let b(v) be the second derivative of -v**4/12 + 4*v**3/3 + v**2 + 2*v. Let y be b(4). Suppose 2*x - 28 = y. Is x a prime number?
True
Let k be (-6)/15 + (-27)/(-5). Let g = k + 17. Suppose g = -2*l + 116. Is l prime?
True
Suppose 5*o - 2 = 13. Suppose 0 = 4*y - o*y - 184. Suppose -5*m + 1479 = y. Is m composite?
True
Let d(i) = 836*i**2 + 2*i + 7. Is d(4) a prime number?
False
Suppose -4*k = 3*o + 4, 3*o = -4*k + 4*o + 12. Suppose j = -l


availability of remineralizing ions at high concentrations near the dentin surface favors their deposition and promotes remineralization.

4. Antibacterial Additives into Resin-Based Root Canal Sealers {#sec4-materials-13-01096}
==============================================================

Antimicrobial agents exert their effects based on one of three different strategies: (1) through their local release; (2) through contact-killing; or (3) through multi-functional strategy to produce synergetic properties \[[@B34-materials-13-01096]\]. The latter offers the advantage of overcoming the drawbacks associated with the exhaustion of the releasing agents and the short-distance killing of the contact-mediated agents. Antibacterial dental resins can also be classified into (1) polymerizable quaternary ammonium compounds and (2) antibacterial filler particles. In the first classification, the antibacterial agent is polymerized within the resin matrix through covalent bonding and does not leach out from the material \[[@B35-materials-13-01096]\]. Below are some of the mostincorporated into AH Plus sealer in combination with 0.15% NAg \[[@B24-materials-13-01096]\]. The authors utilized the DCT to assess the antibacterial properties against planktonic *E. faecalis* over 14 days \[[@B24-materials-13-01096]\]. Groups with DMAHDM maintained a significant CFU reduction over the 14 day period \[[@B24-materials-13-01096]\]. Another study incorporated DMAHDM into a Bis-GMA/ TEGDMA based root canal sealer to overcome drawbacks associated with the incompatible mixing of DMAHDM (methacrylate resin-based), and AH Plus (epoxy-resin based) and to better asses the antibacterial effects of DMAHDM against bacteria in biofilms \[[@B62-materials-13-01096]\]. The authors investigated the antibacterial effects associated with the addition of 5% DMAHDM into the experimental sealer on *E. faecalis* biofilm grown on saliva-coated resin sealer disks and compared the results with AH Plus sealer \[[@B62-materials-13-01096]\]. The authors reported a 4 log


which could lead to the precipitation of less stable mineral particles that can be easily washed out during immersion \[[@B32-materials-13-01096]\].

Amorphous calcium phosphate (ACP) particles have been previously incorporated into various dental resins \[[@B53-materials-13-01096],[@B58-materials-13-01096],[@B75-materials-13-01096],[@B76-materials-13-01096]\]. ACP is the initial phase that forms and then transfers into the more stable Hydroxyapatite \[HA: Ca~10~(PO~4~)~6~(OH)~2~\], through the precipitation of calcium and phosphate ions in supersaturated levels \[[@B54-materials-13-01096]\]. In fact, previous studies have shown the ability of ACP containing materials to release high levels of Ca and PO~4~ ions in aqueous environments, necessary to remineralize the enamel lesions and dentin lesions \[[@B77-materials-13-01096]\].

One drawback related to the incorporation of micro-sized ACP particles is the poor mechanical properties they exert on the material. Recently, through the application of nanotechnology, nanoparticles of amorphous calcium phosphate (NACP) weremore relevant to endodontic practices as root canal sealers such as, AH Plus have previously demonstrated low bond strength measurements but performed well under microleakage assessments \[[@B82-materials-13-01096]\].

The effects of adding MDPB into root canal sealing systems on the bonding and sealing properties were previously investigated \[[@B57-materials-13-01096]\]. Results showed that when 5% MDPB was incorporated, the microtensile bond strength of the sealer system was significantly increased when compared to Epiphany sealer group \[[@B57-materials-13-01096]\]. When observed under scanning electron microscopy, The MDPB sealer system showed an intimate contact with root dentin without formation of any gaps \[[@B57-materials-13-01096]\]. Utilizing a fluid filtration test, the fluid flow rate for MDPB-experimental sealer after 1 week was zero \[[@B57-materials-13-01096]\]. After 4 weeks, the values for the MDPB sealer increased but were significantly lower than


the Epiphany sealer group \[[@B57-materials-13-01096]\]. In another study, 5% DMAHDM, 3%MPC and 20%NACP incorporation into a root canal sealer system did not compromise the push-out bond strength and showed bond strength values that were similar to that of commercial control \[[@B79-materials-13-01096]\].

The microleakage potential of adding 5% DMAHDM and 20% NACP into a root canal sealer was also previously assessed utilizing a methylene blue dye penetration method \[[@B25-materials-13-01096]\]. The authors reported no significant difference in the rate of dye penetration rate when compared to AH Plus commercial control. SEM images revealed the ability of the NACP and DMAHDM containing sealer to infiltrate the dentinal tubules and create numerous resin tags \[[@B25-materials-13-01096]\]. Similarly, when 5% DMAHDM was combined with 0.15% NAg into an experimental root canal sealer, the sealing propertiesWhen QPEI nanoparticles were incorporated into RCS epoxy-based sealer, it was found to be non-cytotoxic \[[@B66-materials-13-01096]\]. The QPEI endodontic sealer showed a decolorization zone of 0 and median cell lysis of 0 (0/0), interpreted as non-cytotoxic.

The biocompatibility of MDPB was previously assessed against human pulpal cells \[[@B86-materials-13-01096],[@B87-materials-13-01096]\]. MDPB showed low levels of cytotoxicity that were similar to that of dimethacrylate monomer, TEGDMA, a commonly used monomer in dentistry \[[@B87-materials-13-01096]\]. When the biocompatibility of MDBP was compared to Bis-GMA, against odontoblast-like MDPC-23 rodent-derived cells, the authors reported lower cytotoxic effects than those produced by Bis-GMA \[[@B88-materials-13-01096]\].

In a study conducted on rats, DMADDM and NACP were incorporated into a composite and adhesive system that was used to restore occlusal cavities prepared on first molars of rats \[[@B60-materials-13-01096]\]. The pulpal inflammatory


bioactive agents into dental products to achieve strong antibacterial and tissue-remineralization functions is highly desirable. These strategies are highly promising to improve the endodontic treatment outcomes and can potentially prevent and control endodontic diseases. However, methodologies that are more clinically relevant need to be employed in future studies to better assess the potential applicability of these new materials. In addition, materials with antimicrobial and remineralizing properties need to be assessed under in vivo conditions that better simulate the oral environment.

This article represents the first review to focus on the effects of the new generation of bioactive endodontic sealers with incorporation of bioactive additives on the antibacterial and tooth mineral-regeneration capabilities. Recent studies developed novel bioactive and therapeutic root canal sealers with antimicrobial properties through the incorporation of additivesM.D.W. All authors have read and agreed to the published version of the manuscript.

This work was supported by the University of Maryland School of Dentistry, and National Natural Science Foundation of China grant 81870759.

The authors declare no conflict of interest.

![Effect of chain length (CL) on dental plaque microcosm biofilm colony-forming units (CFU): (**A**) Total microorganisms, (**B**) total streptococci, and (**C**) mutans streptococci. Two-day biofilms on resins were used for CFU measurements (mean ± sd; *n* = 6). Note the log scale for the *y*-axis. The CFU at CL of 16 was 4 log lower than that of SBMP control. In each plot, values with dissimilar letters are significantly different from each other (*p* \< 0.05). Adapted from \[[@B50-materials-13-01096]\] with permission.](materials-13-01096-g001){#materials-13-01096-f001}

![Images of *E. faecalis* following contact with the novel


revealed. That being said, we know at least one major phone is coming from HTC in the first half of 2015, and another top tier phone like an HTC One (M9) Max could arrive in the second half to battle the Galaxy S6 and iPhone 6S Plus.

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A new report has surfaced about a phone that could be the HTC One M9, or something completely different. It states the phone will have the exact same specs internally as the HTC One M9, which are impressive, but this phone will have a huge 5.5-inch display with nearly no bezels. Similar to the LG G3 or Sharp AQUOS that has such small bezels the screen looks like it’s floating. This essentially once again confirms the M9, as well as tips usChanging The Title Industry

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certain standards did develop. Specifically, the area of incision on the patient's body must be cleaned thoroughly with a scrub or soap solution for a period between 3 to 10 minutes. Most surgical operations, other than orthopaedic surgery, require 3 minutes of scrubbing time; orthopaedic surgery requires 10 minutes of scrubbing time due to the increased risk of infection. After the scrubbing procedure, the area is dried with a sterile wipe and antiseptic solution is applied. For some procedures, other than orthopaedic surgery, the scrub portion of the procedure is eliminated and only the antiseptic solution is applied. In either case, the standard procedure for applying either the scrub or the antiseptic solution involves starting from the middle of the treated area and proceeding outward in circular orhe's been hurting me during breastfeeding!

*~*

His Tita Ninang's loving laugh also filled our home after she saw the teeth. And MIL texted to tell us she's cooking igado and fried chicken for him when next we visit.

Mommy Mec

Yakee & Yamee

Rubeus Iakob loves the outdoors, animals, dinosaurs, trucks, superheroes, books and Oreo. Good enough Kuya. Read more about his progress at his own blog.

Yannis Mikah has a greater appetite, loves blinking lights and going out and is growing a very persistent, stubborn personality. Good enough bunso. Read more about his progress at his own blog.

30-something and childlike, the couple continue their baby steps towards a more meaningful relationship, a crazier, happier love and well-invested years of discovery and growth. Ngarag but loving Intentional Parents to two boys. Favorite activities


Sir Azarphan has been a Death Knight for so long that he only remembers a few things from his mortal life. One of the things he remembers quite clearly is, of course, the vow he made that was broken. The broken vow that created the monster that he is is now.when you think about it.

From FB's perspective, this would harm your privacy, because FB will have to find even more creative and treacherous ways to invade user privacy to make up for the fact that users could, at any time, choose to have said data removed. I could easily imagine them creating multiple shell corporations that really "store" your data, and then when you ask to have your data removed they simply say "sorry, we don't store your data, one or more of our many affiliate corporations store and manage user data.. you'll have to submit your requests to them..."

To grant one person the right to not be punched is to deprive another of the right to punch.Who's rights are more important? The puncher, or the punchee?Your right


purpose, even in places where state or local law does."

Get Breaking News Delivered to Your Inbox

According to the USCIS, even the use of medical marijuana or jobs associated with the cannabis industry could bar an immigrant from establishing "good moral character" and earning citizenship.

"U.S. Citizenship and Immigration Services is required to adjudicate cases based on federal law," Collins said. "Individuals who commit federal controlled substance violations face potential immigration consequences under the Immigration and Nationality Act (INA), which applies to all foreign nationals regardless of the state or jurisdiction in which they reside."

There is an exception if a violation is a single offense for simple possession of 30 grams or less of marijuana.

Currently, 33 states and the District of Columbia have legalized medical marijuana, and 10 states andthe District of Columbia have legalized recreational marijuana for adults.

Sixty-five percent of Americans now think marijuana should be legal — a record high in CBS News polling. Most view marijuana as less harmful than alcohol and believe it is less dangerous than other drugs.


called, in Cornwall, helling to this day; and the covers of books in Lancashire by the same name
-- so the literal import of the original word Hades was formerly well expressed by it." CAMPBELL,
DODDRIDGE, CLARKE, PARKHURST, and others. I saw lately in an English newspaper, an
account of an accident which happened to a Slater, who "fell from the roof while engaged in helling
it."]

And now let us turn to the New Testament, and we shall find that Hades, in its literal usage, is the
equivalent of Sheol, signifying,

I. The grave, the underworld, or place of the dead.

The first pasage to be noted is 1 Cor. 15:55. "O death where is thy sting? O grave (hades) where is
thy victory." Here hades is properly translated, the resurrection being very appropriately celebrated
as victorylib. xxv. c.13. THEOPHYLACT, A.D., 1050, elaborates this
as a probable interpretation. -- Trench on the Parable.]

Thus we see that while "Abraham's bosom," which is a Jewish idiom or phrase for the blessed life
of paradise, represents the exaltation of the Gentile world to the privileges of God's chosen people;
Hades, or the state of death, represents the national death of the Jews, or their utter desolation and
ruin as a people.

But we discover from this parable, that in the time of Christ, the Jews had partially adopted the
pagan ideas respecting Hades, or the Underworld, viz: that it contains separate apartments for the
good and bad; and that in Tartarus, the portion assigned to the wicked, there were torments, flames,
etc., in punishment of their sins.

This, and 2 Pet. 2:4, are the only passages


destruction:" Dr. Campbell says, on Rev. 20:14, "if we interpret Hades, 'hell,' in the Christian
sense of the word, the whole passage is rendered nonsense. Hell is represented as being cast into
hell; for so the lake of fire, which is in this place denominated the second death, is universally
interpreted." The phrase "cast into the lake of fire" is a figure of utter destruction. It is simply saying
"death and hell were destroyed."

4. Of course, then, Hades, "hell," is not a place of endless torment, otherwise it could not be
destroyed. Whatever, therefore, the interpretation given to the narration of Dives and Lazarus,
whether regarded as a parable, or literal history, it is plain that the Rich Man was not in a place of
endless torment. Or, in the more general phrase of Prof.Anti-TNF modulation reduces myocardial inflammation and improves cardiovascular function in systemic rheumatic diseases.
Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are common disorders associated with increased rates of cardiovascular disease (CVD), but the contribution of cytokine-induced inflammation to impaired cardiovascular function in these conditions remains poorly understood. We assessed the effect of anti-TNF therapy on myocardial and vascular function, myocardial tissue characteristics and perfusion in inflammatory arthropathy and systemic rheumatic disease (IASRD) patients, using cardiovascular magnetic resonance (CMR). 20 RA patients, 7 AS patients, 5 PsA patients without previously known CVD scheduled to commence anti-TNF therapy and 8 RA patients on standard disease modifying antirheumatic drugs underwent CMR at 1.5 T, including cine, tagging, pulse wave velocity (PWV), T2-weighted, native and postcontrast T1 mapping, ECV quantification,


significantly longer time to first erythrocyte transfusion than the control group and were less likely to experience nadir haemoglobin levels < 10 g/dl (P < 0.001 and < 0.05, respectively). A haemoglobin decrease < 1 g/dl during the first chemotherapy cycle, as well as a low baseline serum erythropoietin concentration, predicted a low transfusion need in rhEPO-treated patients but not in controls. During the study, 103 patients suffered at least one adverse event, but no serious, and only nine non-serious adverse events were considered possibly related to rhEPO therapy. These results indicate that treatment with rhEPO prevents anaemia, it reduces the need for blood or rhEPO erythrocyte transfusion in patients with ovarian cancer receiving platinum-based chemotherapy, and it is well tolerated. A starting dose of 150 U/kg ofINTRODUCTION
============

Ventral and incisional hernia repair is one of the most common operations performed in everyday clinical practice. Incisional hernia is a common long-term complication of abdominal surgery and is estimated to occur in 11--20% of laparotomy incisions.^[@B1],[@B2]^ Almost 50% of incisional hernias develop within the first 2 years after the primary surgery, and 74% develop after 3 years.^[@B3],[@B4]^ The recurrence rate of incisional hernia after primary suture repair is more than 50%^[@B5]^ and has been reduced to 10--23% after the introduction of prosthetic materials (meshes) in hernia repair.^[@B6]^

However, open hernia repair can be a major operation with considerable morbidity caused by infectious complications. An increasing interest in laparoscopic surgery and the availability of new materials have encouraged the adoption of laparoscopic techniques in ventral hernia repair. Leblanc and


sutures combined with 1 row of spiral tacks or tacks placed in a double-crown pattern was used. In addition, a recent systematic review by Reynvoet et al^[@B52]^ failed to show any advantage in recurrence rate in association with the fixation method used (ie, the use of tacks and sutures, tacks only, or sutures only). However, the general opinion of most surgeons is that a dual method of fixation with tacks and sutures is necessary for a more robust repair.^[@B27]^

A mesh overlap of at least 5 cm and fixation of the lower margin of the mesh to the Cooper\'s ligament confers increased durability and reduces the possibility of recurrence in patients with suprapubic hernia. Insufficient coverage of the incision scar is a risk factor for recurrence after LVHR. Therefore,or an enterotomy (**[Figure 3](#F3){ref-type="fig"}**).^[@B27]^Cases of previous repair with a mesh infection usually necessitate abdominal exploration, washout of the contaminated wound, drainage of fluid collections, and often, mesh removal. After an interval period of 2 to 3 months, a second open repair is necessary, with placement of the biological mesh.^[@B65]^Open surgery is necessary in cases with severe contraindications for laparoscopy in the patient\'s status, such as cardiorespiratory insufficiency, abnormalities of hemostasis, or ascites.

![For very large nonreducible or strangulated hernias, especially with a gangrenous bowel, open repair is indicated.](jls9991535200002){#F2}

![In cases in which a piece of mesh from a prior repair is densely adherent to the bowel, a small piece of mesh may be excised and left attached to the bowel to prevent deserosalization or an opening of the bowel


dia̍p/lia̍p ( / ): twenty; 20 (same format for 20-29, i.e. 二十一[21] is "dia̍p-it" 廿一)
saⁿ-tsa̍p () > sap (): thirty; 30 (same format for 30-39, i.e. 三十二[32] is "sa̍p-dī" 卅二)
sì-tsa̍p () > siap (): forty; 40 (same format for 40-49, i.e. 四十三[43] is "siap-saⁿ" 卌三)

Vocabulary
Philippine Hokkien, like other Southeast Asian variants of Hokkien (e.g. Singaporean Hokkien, Penang Hokkien, Johor Hokkien and Medan Hokkien), has borrowed words from other languages spoken locally, specifically Tagalog and English. Examples include:
 manis : "corn", from Tagalog
 lettuce  : "lettuce", from English  + Hokkien  ("vegetable")
 pamkin : "pumpkin", from English

Philippine Hokkien also has some vocabulary that is unique to it compared to other varieties of Hokkien:
  : "chauffeur"
  : "cement"
  : "country bumpkin"
  :Hadoop Matters Blog

A new survey of data science tools shows that Python usage is quickly gaining steam among advance analytic professionals, at the expense of both R and SAS. According to the results of the 2016 survey, conducted by Burtch Works, R is the preferred tool for 42% of analytics professionals, followed by SAS at 39% and Python at 20%. While Python’s placing may at first appear to relegate the language to Bronze Medal status, it’s the delta here that really matters.

What is Spark?

Apache Spark is an open source big data processing framework built around speed, ease of use, and sophisticated analytics. It was originally developed in 2009 in UC Berkeley’s AMPLab, and open sourced in 2010 as an Apache project.


a couple is expected to pay $1500 to 4500 to the midwife. Hospital births can range from $3,296 to 37,227, although they are usually covered totally or partially by the insurance. Of note: adoctor gets paid about $2500-4000, same as a midwife. Ιn Europe, a couple is expected to pay about 2000-3000 €; recently the Italian newspaper La Stampa published the article Home birth: a 3000 € luxury that does not convince doctors.

Indeed, Mother nature is great. If you think about it, the whole process of labor and delivery seems to be so perfect, almost magical… But “natural” is not a synonym of “risk-free”. Sometimes Mother nature can play strange games. We may believe we have everything under control, but things may flip just in a second: thinkcare unit, uterine rupture, blood transfusion, etc) and found that women who delivered their first baby at home had the same risk with women delivering at a hospital, but parous women had increased risk of postpartum hemorrhage and blood transfusion when delivering at a hospital; however, another study, also from the Netherlands, did not confirm these findings. Therefore, a hospital birth leads to more interventions, but it does not seem to increase the risk of serious maternal complications. Regarding maternal deaths, they are a rare event; thus it is not possible to draw conclusions from the studies.

There is something that every woman considering home birth should understand: the studies results apply only to very low-risk pregnancies. Higher risk women, such as those with twin pregnancies, previous cesarean sections,


to evaluate the efficacy of the nine-valent vaccine. Gardasil 9 prevented 97% of high-grade precancerous lesions of the cervix, vulva, and vagina caused by the five new high-risk HPV types (HPV31/33/45/52/58) (21). The nine-valent vaccine also generated immune responses to HPV6/11/16/18 that were as good as or better than those generated by the quadrivalent vaccine. (4, 22)

6. Safety of the HPV vaccine

Many studies have evaluated HPV vaccine safety, both before their commercialisation and post-release, which demonstrated no differences in side effects as compared to control groups, irrespective of age and ethnicity (23).

According to the CDC, the most commonly reported side effects of the vaccines are:

Pain, redness, or swelling in the arm where the shot was given

Fever

Headache or feeling tired

Nausea

Muscle or joint pain

Fainting (also known as syncope) and relatedJapan was the first country reporting on several girls suffering from severe pain and disability; these cases were heavily publicised in newspapers, TV news and social media, but they also alarmed the medical community. Japanese physicians published later on a series of 44 girls who were diagnosed with complex regional pain syndrome(CRPS) (35). Due to these concerns, in June 2013 the Japanese Ministry of Health, Labour, and Welfare (MHLW) decided to suspend its active recommendation of HPV vaccination. This decision created intense debate among scientists and general public, which continues until nowadays (34).

In March 2015, Denmark‘s TV channel TV2 aired a documentary entitled The Vaccinated Girls – Sick and Betrayed. The journalists gathered about 60 girls from all over Denmark who became sick shortly after receiving the HPV


who developed a chronic ailment soon after receiving the HPV vaccine. “A disabling syndrome of chronic neuropathic pain, vexing fatigue, and profound autonomic dysfunction may appear after HPV vaccination,” say the authors, headed by Manuel Martínez-Lavín, MD, a specialist in chronic pain conditions from Mexico City. After a mean period of 4 years following HPV vaccination, 93% of individuals “continue to have incapacitating symptoms and remain unable to attend school or work,” write the authors (38).

POTSafter HPV vaccination has also been reported in the United States. Dr. Blitshteyn, a neurologist from New York, described six patients who developed POTS between 6 days and 2 months after HPV vaccination. All patients reported improvement over 3 years, but residual symptoms persisted (39).

The US Food and Drug Administration (FDA) and theto potential vaccine side effects in order to protect girls, or to prevent a so rare type of cancer (responsible for just 300 deaths in the USA); whether the benefit outweighs the risk and if men vaccination is cost effective. While countries such as Australia and the USA include boys in their vaccine recommendations, other countries (i.e., UK and France) have not yet adopted this measure.

Men who have sex with men are a special category, since they are at higher risk of anal cancer. Thus, some experts believe these men (and not every boy) should be offered the vaccine. However, this measure may be difficult to implement: in order get covered by their insurance or social security, young men may be required to declare their sexual preferences.

Immunogenicity of


assembly 820 into a hub 811 of catheter 800, and, once connected, a valve/seal member (for example, like that described in U.S. Pat. Nos. 5,125,904, 5,312,355 and 5,409,463), which is located within a body 825 of assembly 820, in proximity to a proximal end 824 thereof, both seals off a lumen of catheter 800 and provides a passageway into the lumen. This passageway, into the lumen of catheter 800, is intended to allow passage of a medical device, for example, a medical electrical lead, therethrough, so that the operator may deliver the device, through the lumen of catheter 800, to a target site, within a body of a patient. The valve/seal member of assembly 820 is designed to seal around the device as it passes therethrough and therebyThe present invention relates to a method of, and apparatus for, receiving and transacting a customer's order for photofinishing.
Conventionally, exposed photographic films such as negative films are forwarded to agencies mediating the customer's orders for photofinishing, wherein each film is packed in a prescribed customer's order envelope after writing necessary information, such as the name of the customer and the content of the order, on a predetermined portion of the envelope. Then, the envelopes containing the photographic films are forwarded to a photofinishing laboratory (hereinafter simply referred to as a "photo-lab"). In the photolab, the envelopes are manually sorted according to the content of the order written thereon.
Because of such a manual transaction of print orders, a misreading of the written information and thus a mistake in sorting


Q:

Warning: mysql_fetch_array() expects parameter 1 to be resource, boolean given when updating record

I am updating a mysql table. i am getting an error as below

Warning: mysql_fetch_array() expects parameter 1 to be resource, boolean given in C:\xampp\htdocs\test\edit.php on line 232
  Error. You have an error in your SQL syntax; check the manual that corresponds to your MySQL server version for the right syntax to use near '' at line 1

The query seems not to be producing a result. I am passing an id to a function via a url but the variable seems to die although it seems to be in scope. What could be my error. The loop for the update is below. i have commented out some lines which i thought where a problem but they      $data = mysql_query($sql);
                            while($rows = mysql_fetch_array($data)){
                                echo "<option value={$rows['name']}>";
                                echo $rows['name'];


type=\"hidden\" value=\"{$rows['selection_id']}\" name=\"sid\">
"; // create hidden field with selection_id which enables the right selection to be edited
                    echo "
	<input type=\"submit\" value=\"Update Selection\" name=\"editSelection\">
";

                    echo "
</form>";
            } //end of while loop
        }

A:

mysql_query() returns a result set if it works, or false if it doesn't work. The fact that you're getting complaints from mysql_fetch_array() about using a boolean where a result set is required means that the query has returned false (ie, it hasn'tthan high‐risk group (*p* = 0.038), with median OS time were 618 and 423 days, respectively (Figure [3](#mgg3729-fig-0003){ref-type="fig"}b). Be similar to TCGA cohorts, both HSBP1L1 and MRPL3 were highly expressed, DNAH10 and KIAA0513 were lowly expressed in high‐risk group (Figure [3](#mgg3729-fig-0003){ref-type="fig"}d). The detailed HR and *p*‐value were presented in Figure [S2](#mgg3729-sup-0002){ref-type="supplementary-material"}, in which low‐expressed DNAH10 and KIAA0513 were proved to be robust for prognosis prediction. Thus, the four genes signature was potential prognostic marker for pancreatic carcinoma, based on RNA sequence data.

3.4. Differential gene expression and functional enrichment analysis {#mgg3729-sec-0017}
--------------------------------------------------------------------

To reveal the important molecular events, accounted for the prognosis, DEG were calculated in TCGA cohort. As shown in the volcano plot (Figure [5](#mgg3729-fig-0005){ref-type="fig"}a), a list of 579 genes were identified, of which 454 genes were up‐regulated, and 125 genes were down‐regulated.


75 percent of the U.S. population. The higher-speed network is important as the company works to meet the increasing needs of customers who are using smartphones, tablets and more, to manage their lives and run their businesses. The FCC estimates that the industry demand for mobile data by 2015 will be 25 to 50 times greater than it was in 2010 as customers move toward more data-intensive devices that allow them to video chat, stream live video, download movies or large work files and more, on smartphones and tablets.

Verizon Wireless remains committed to helping America lead the world in broadband infrastructure that will ultimately give consumers more choice, convenience and innovation.

Alliance for Broadband Competition Statement on FCC Verizon-SpectrumCo Order

The Alliance for Broadband Competition released the below statement following    'string'  => 'Το στοιχείο :attribute πρέπει να είναι μεταξύ :min και :max χαρακτήρες.',
        'array'   => 'Το στοιχείο :attribute πρέπει να έχει μεταξύ :min και :max αντικείμενα.',
    ],
    'boolean'              => 'Το στοιχείο :attribute πρέπει να είναι είτε αληθές είτε ψευδές.',
    'confirmed'            => 'Η επιβεβαίωση του στοιχείου :attribute δεν ταιριάζει.',
    'date'                 => 'Το στοιχείο :attribute δεν είναι έγκυρη ημερομηνία.',
    'date_format'


deleting them and the temp files can be huge depending on your settings. One you get it going again I would choose a bigger drive for you scratch disk if that's an option.

I changed the Photoshop scratch disk to a fast external conventional hard drive. This, by the way, is the way you should be running if you don't have an internal SSD as your system drive. If your system drive is a regular hard drive, putting the scratch files there only sets you up for what's known as “drive thrashing.” The disk head has to bounce all over the place to keep up with the

By default your scratch disk is your Boot Partition, which already handles all your installed applications and the operating system. It is advisableQ:

How to extract content from HTML strings

I want to extract contents from DIV tag. I am using scrapy to scrap some site but the problem is Same DIV tag has two type of contents:
["
\n                <s>Rs.330</s> Rs.297\n
"]

And
["
\n                Rs.330              \n
"]

How do I extract contents from this tag?

A:

Use BeautifulSoup:
import bs4

html = "
\n


              <s>Rs.330</s> <b>Rs.297</b>\n                              </div>"
soup = bs4.BeautifulSoup(html, features="xml")
s = soup.div.s.text # u'Rs.330'
b = soup.div.b.text # u'Rs.297'

zmq_tcp(7)
==========

NAME
----
zmq_tcp - 0MQ unicast transport using TCP

SYNOPSIS
--------
TCP is an ubiquitous, reliable, unicast transport. When connecting distributed
applications over a network with 0MQ, using the TCP transport will likely be
your first choice.

ADDRESSING
----------
A 0MQ endpoint is a string consisting of a 'transport'`://` followed by an
'address'. The 'transport' specifies the underlying protocol to use. The
'address' specifies the transport-specific address to connect to.

For the TCP transport, the transport is `tcp`, and the meaning of the
'address' part is defined below.

Assigning a local address to a socket
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
When assigning a local address to a socket using _zmq_bind()_ with the 'tcp'
transport, the 'endpoint' shall be interpreted as an 'interface' followed by a
colon and the TCP port number to use.

An 'interface' may be specified by either of the following:

* The wild-card `*`, meaning all available interfaces.
* The primary


It would also take care of setting up bindings between the View and ViewModel objects.

So, opening a form or page would involve executing a function to generate a ViewModel object instance, and then passing that to the function that builds a View from the ViewModel, and then setting that as the content of your Window.  From that point on, it executes in a normal "mutable" MVVM way.
My knowledge of F# is still limited, so I may be going down the wrong rabbit hole here.
Question(s):

Will this work (in general), or not?
Is there a better way that you know of?

A:

I don't know much about ADO.NET entities, or MVVM, or WPF, so I can't offer much critique of the technical ideas personally.  It sounds like you have experience with         // (disable drawing controls after the first one has been drawn)
           drawingManager.setDrawingMode(null);
           drawingManager.setOptions({
              drawingControl: false
           });

           // The drawn area is editable with mouse so also want to
           // update the html form when the area is edited
           google.maps.event.addListener(event.overlay, 'bounds_changed', function() {


a whole, I just hope that the right people that have the money and capabilities do so in a way that gives all nations a equal chance in space exploration. [url=https://www.youtube.com/watch?v=NtQkz0aRDe8][u][color=#0066cc]https://www.youtube.com/watch?v=NtQkz0aRDe8[/color][/u][/url]

eventually there should be a moment when the entire universe could pop-up into existence again but this instant is way, way farther away, around a googolplex of times more than the time you would have to wait to get to the Boltzman brain part of the video (remember, this is with exponential increse in the speed of the video).

This is exactly as I see it, and you could have a oscillating universe in this way!

Silly video with lots of bias, we have enough desalination tech to heavily desalinate if we were ever forced into that situation. Nanotech runningSupply Chain Management is increasingly been positioned as a key strategic enabler helping organisations to add value and push the boundaries of performance

The modern day buyers are more and more pretentious; the organisational staff members are more and more demanding; the competitive environment is more dynamic; the legislations change and the technology evolves. Virtually, the internal and external environments of the firms are in a continuous process of change and the organisational leaders have to devise a wide array of mechanisms by which to cope with the new challenges, to take advantage of their opportunities and to limit their threats.

One important tool used in this direction is represented by Supply Chain Management. The current project as such sets out to assess the Supply Chain Management (SCM) through the


employees for instance, these come to play a growingly important role within the modern organisations, as they add value through their intellectual capital. But on the other hand, the employees are also more demanding and require more resources to be invested in their hiring, retention, preparation and rewarding.

The customers of today also grow more demanding, especially since they are presented with a wide selection of products and services from which to choose those that best serve their needs. In other words, competition grants more power to the buyers. But competition also forces the economic agents to develop and improve, or else risk demise.

Other challenges posed by the external environment include the changes brought to the legislations regulating the business community, the advance of technology or the increasing pressures$this->assertEquals($bag1->allPreserveCase(), $bag2->allPreserveCase());
    }

    public function testToStringIncludesCookieHeaders()
    {
        $bag = new ResponseHeaderBag([]);
        $bag->setCookie(Cookie::create('foo', 'bar'));

        $this->assertSetCookieHeader('foo=bar; path=/; httponly; samesite=lax', $bag);

        $bag->clearCookie('foo');

        $this->assertSetCookieHeader('foo=deleted; expires='.gmdate('D, d-M-Y H:i:s T', time() - 31536001).'; Max-Age=0; path=/; httponly', $bag);
    }

    public function testClearCookieSecureNotHttpOnly()
    {
        $bag = new ResponseHeaderBag([]);

        $bag->clearCookie('foo', '/', null, true, false);

        $this->assertSetCookieHeader('foo=deleted; expires='.gmdate('D, d-M-Y H:i:s T', time() - 31536001).'; Max-Age=0;


     $bag->setCookie(Cookie::create('foo', 'bar', 0, '/path/foo', 'foo.bar'));
        $bag->setCookie(Cookie::create('bar', 'foo', 0, '/path/bar', 'foo.bar'));
        $this->assertTrue($bag->has('set-cookie'));

        $cookies = $bag->getCookies(ResponseHeaderBag::COOKIES_ARRAY);
        $this->assertArrayHasKey('/path/foo', $cookies['foo.bar']);

        $bag->removeCookie('foo', '/path/foo', 'foo.bar');
        $this->assertTrue($bag->has('set-cookie'));

        $cookies = $bag->getCookies(ResponseHeaderBag::COOKIES_ARRAY);
        $this->assertArrayNotHasKey('/path/foo', $cookies['foo.bar']);

        $bag->removeCookie('bar', '/path/bar', 'foo.bar');
        $this->assertFalse($bag->has('set-cookie'));

        $cookies = $bag->getCookies(ResponseHeaderBag::COOKIES_ARRAY);
        $this->assertArrayNotHasKey('foo.bar', $cookies);
    }

 technology, we expect that we can eliminate a lot of these, making the overall process faster and more cost effective.”

Royal Dutch/Shell is taking it a step further, investing in a minority stake in the distributed ledger startup Applied Blockchain. The blockchain firm has created platforms across a range of sectors including telecom, manufacturing, and more.’

Petroteq and the Blockchain
While the supermajors are focused on trading, others are looking to the tech for far more creative endeavors.

Petroteq (OTC: PQEFF; TSX-V: PQE), a company that made waves in the sector with its revolutionary patented oil sands tech, has set out on a mission to completely overhaul the industry’s inefficient and error prone supply chain management protocols.

Petroteq was recently cited by Geoffrey Cann, a Director at Deloitte specializing in the oil and


know what, I like the authentici... ty." "Fuck, Orlando!" "Just because he drinks water from the toilet bowl and eats food from the floor, and he doesn't mind putting his nose up another dog's bum-bum, doesn't mean you can make him do that." "I just think that it's a sad, sad world." "If you're going to sit here, stop whining." "SHE SNIFFS" "You're not leaving until you apologise." " Get out of my way." " You haven't changed." "You're trying to provoke me to touch you." "I'm afraid I won't." "You can't stop hurting people." " I'm surprised they don't despise you." " Oh, they do." "I sleep with Cleveland, Sam," "John, Paul, and Gaultier." "But it's not biblical to judge or hate." "Furthermore, no-one will tell Cleveland."that content, they know perfectly well that any user can supersede this with local CSS, and so I don't see how they have any legal claim, nor any way of knowing if you have accessed the "hidden" content or not.
If you attempt to bypass or hack a login screen, that might be circumvention under the US DMCA, or "Unauthorized computer access" under any of several laws.


German concentration camp, he recited the Holy Books of Thelema to himself, which aided him in performing one of the central tasks of the A∴A∴, being the attainment of the experience known as "the Knowledge and Conversation of the Holy Guardian Angel”, the attainment of which is the central theme of the order's official instructions.

References

Footnotes

Bibliography

Category:1885 births
Category:1962 deaths
Category:Members of Ordo Templi Orientis
Category:American Thelemites
Category:German Thelemites
Category:People from Elberfeld
Category:Nazi concentration camp survivors
Category:Holocaust survivors
Category:German refugeesKnox
Polk Rutledge, known as "Lum", was born December 23,
1844. He was also a Confederate

This is a letter explaining some of the thoughts about Wilson's
family. My interest in Wilson is that I believe Wilson to a
brother of my ggg-grandfather James A. (I HAVE NO PROOF OF THE
RELATIONSHIP) Their families lived at the same place at the same
time, BUT the James who is supposed to be the father of Wilson
and John Rutledge lived with my James in Cherokee Co. AL. Mike
Rutledge, Boaz AL WILSON (W.A.) RUTLEDGE Born ca 1803) in NC Died
21 Feb. 1863 of typhoid fever while A POW-CSA, Camp Douglas, IL.
MARRIED TWICE: (1) md ca 1829 possibly in Monroe Co. TN. She has
not been identified; no marriage record found. ISSUE: 3, possibly
4, sons, and 1 daughter. 2) md


R W Harrison father to Joe,
Ed, Pearline and Agnes. Dad is buried next to Grandma Kelly and a
younger half brother (dy). Marie Subject: [RUTLEDGE-L] Flora Owen
Date: June 24, 1999 12:59 AM Kathye, Kay, Marie,
Montez..........just reviewing the burials at Mt. Hebron Cemetery
in Arkansas. I never noticed before that Dad's mother Sarah Flora
Owen (1882 - 1946) is buried there as Sarah Harrison. I
completely forgot that she was married to Uncle Harrison when she
died. Don't get the wrong idea
our childhood Uncle Harrison was
the father of two of our cousins. His wife then , Perlene, was
the sister of my mother's mother, who's maiden names were Beebe.
Don.

Sorry, I have no real data yet on my AR Rutledge bunch and where
they settled...have few residence, marriage and burial locations
such as Washington, Pulaski and Boone Counties,been imprisoned in IL.

Have much on those Rutledge siblings that settled in AZ areas of
Prescott and Verde Valley in Yavapai County, if anyone ever
needs.

Richard

Pam, I enjoyed reading your info on Ripley Co., MO - thank
you! Husband Roger's Great Grandmother, Mary Elizabeth Rutledge,
married Obadiah Goodman (about 1890, place unknown). Obadiah's
father, McElyea Goodman, married his 3rd wife, Rebecca J. Dailey,
on July 09, 1878 in Ripley Co., MO. I wonder if there might have
been Rutledge's right over one of the County lines... or the AR
line. (?) Mary Elizabeth was born/raised in either Dent or Texas
County, MO but apparenly her mother moved to Reynolds Co after
her Dad died on 4 Dec 1889. Reynolds is separated from Ripley Co
by Carter Co... Might be lots of interesting things in those
three counties! Thanks again!

Kay

From Lawrence


contest sure to have finals implications, while the Sharks and Sea Eagles will be live on Channel Nine's Sunday Football for the last live free-to-air game of the regular season.

Use the NRL.com Ladder Predictor to see who you think will make the 2015 NRL Finals

See the full 2015 NRL Telstra Premiership drawQ:

How can I make python wait untill a webpage loads some data I'm trying to get?

I need to get some numbers from this website
http://www.preciodolar.com/
But the data I need, takes a little time to load and shows a message of 'wait' until it completely loads.
I used find all and some regular expressions to get the data I need, but when I execute, python gives me the 'wait' message that appears before the data loads.
Is there a way to make python 'wait' until all data is loaded?
my code looks like this,
import urllib.request
from re import findall

def divisas():

pag = urllib.request.urlopen('http://www.preciodolar.com/')
html = str(pag.read())
brasil = findall('(.*?)	',html)
return brasil

A:

This is because the page is generated with JavaScript. You're getting the full HTML, but the JavaScript handles changing the DOM and showing the information.
You


with the increasing urbanization may have led to the selection of particular detoxification genes and to an increased tolerance to pesticides [@pone.0030989-David1], [@pone.0030989-Poupardin1], [@pone.0030989-Riaz1], [@pone.0030989-Djouaka1].

In this study we investigated the insecticide resistance level and the associated molecular mechanisms in nine *Ae. aegypti* populations collected in several ecological settings in Martinique island. A statistical multifactorial approach was adopted to investigate the possible relationship between resistance levels, associated mechanisms and environmental factors such as agriculture, pollution and urbanization in Martinique populations.

Materials and Methods {#s2}
=====================

Mosquito strains and populations {#s2a}
--------------------------------

Two laboratory strains from French Polynesia (Bora-Bora) and Benin (SBE) and nine field-caught populations were used in the study. The two laboratory strains are susceptible to all insecticides and have been used as reference strains for resistance assays and as outgroups in order(7--18,19)     23%
  VCLN                                    1,27 (1,28--1,27)   1,16 (1,13--1,26)   27,5 (24,67--31,52)    152,88 (116,79--211,41)   5,71 (5,14--6,79)   7,14 (5,95--10,52)    20%
  RSAL                                    1,4 (1,42--1,39)     1,2 (1,18--1,3)    28,75 (26,33--32,73)     81,69 (64,82--110)


                     47   0,053 (±0,0079)[\*](#nt103){ref-type="table-fn"}   0,125 (±0,0127)[\*](#nt103){ref-type="table-fn"}   0,098 (±0,0188)[\*](#nt103){ref-type="table-fn"}   0,051 (±0,0463)[\*](#nt103){ref-type="table-fn"}

Susceptible reference strains.

\*: Values significantly different in field-caught populations comparatively to the Bora laboratory strain (Mann and Whitney\'s test, p\<0.05). sd: standard deviation.

*Kdr* genotyping {#s3c}
----------------

Sequencing of the voltage-gated sodium channel gene from single mosquitoes revealed the presence of the *Kdr* mutation at position 1016 (GTA to ATA) leading to the replacement of a valine by an isoleucine (V1016I) at a high allelic frequency for all of Martinique populations (f\[R\] ranged from 0.87 to 0.97, [Table 3](#pone-0030989-t003){ref-type="table"}). All the populations were at Hardy-Weinberg equilibrium (Exact test, *P*\>0.05). No other *Kdr* resistant alleleIslands [@pone.0030989-Harris1], suggesting that other undiscovered target site mutations might also contribute to pyrethroid resistance.

Enzymatic phenotyping of AChE1 did not allow demonstrating the presence of the G119S and F290V mutations in organophosphate resistance in mosquito test population from Martinique. However, the RSAL population presented a slightly lower inhibition rates for dichlorvos and propoxur compared to other populations. The sequencing of the *Ace.1* gene in this population should confirm the absence of this mutation in Martinique. Unless other mutations are present elsewhere in this gene, our results showed that organophosphate resistance is mainly due to metabolic mechanisms.

By quantitative trait loci (QTL) mapping, Saavedra-Rodriguez et al. [@pone.0030989-SaavedraRodriguez2] confirmed that genes coding for detoxification enzymes play a significant role in pyrethroid resistance in *Ae. aegypti*. Biochemical assays on adults showed that


of the P450 detoxification system in metabolic resistance mechanisms in Martinique.

The over-transcription of the gene *GSTE2* is of particular interest since the associated enzyme has been shown to metabolize DDT in *An. gambiae* and *Ae. aegypti* [@pone.0030989-Lumjuan1], [@pone.0030989-Ortelli1]. *GSTE2* was also found over-transcribed in a DDT- and pyrethroid-resistant mosquito population from Thailand [@pone.0030989-Lumjuan1]. The intensive use of DDT and other organochlorines may be at the origin of the selection of the constitutive over-transcription of *GSTE2* in Martinique. The gene *GSTE7* was also found over-transcribed in several Martinique populations, and in several pyrethroid resistant *Ae. aegypti* strain from Thailand [@pone.0030989-Strode1]. Recent studies performed in our laboratory showed that this enzyme show a GSH conjugation activity and is able to bind several insecticides and pollutants such as DDT, pyrethroids andTag Archives: Trinosofia images

The first painting – a bird shaped lamp – in fact belongs to the end of Trinosofia Chapter Two. A guiding star led the initiate through a white door to the turbulent waters of life – Chapter Three – into which he dived, and was tempted by temporal power. You can read Manly P Hall’s translation of each chapter (as I go along), in the Trinosofia Texts page in the title bar.

I have a technical problem with reproducing my drawings here. The yellow in my originals is soft and subtle. But it scans out hard and greenish. Even if I erase the yellow in the original, its shadow is still there. This happens when yellow is placed on white or next to white; if yellow


in – adapting it to my inner vision. It too is a lens – an eye. The lit up rocks shine like gold. There’s a little interior landscaping, of trees and a house in the dawn. It is mysterious. Compositionally I am the darkness looking out and into which the redeeming dawn shines. There is a spiral swirl of scribble rock formation.

It belongs with some earlier (1980s) sketches of the inner eye: a sunlit landscape within the cliffs of fall: the Hermetic Underbeing. A friend commissioned from me an oil painting to illustrate G M Hopkins’ poem “O Mind, thou hast Mountains, Cliffs of Fall“. The painting was subsequently stolen from him, and all that I have is this blurred photo. Some years later, I re-drew and paintedare also apparently sacred letters on the flank of the lion.

To go into the surging sea in this path through the white pure door of the Adept, is Courage into the vibration, into noise-interference to which I am hypersensitive and judgemental. The Holy One is at the heart of All. Receive and rock with the impressions, unconditionally, tendering their timeless points, and smiling. The Lord of the World sinks: I am carried by the Waters, swimming by my effort. The green sand of the shore is in the sense that the sand is like the Spirit, blown in whorls by the wind, and has the same gematria as blood; and when you melt sand it turns to glass – the crystal of the Soul. Here it is green


college applicants can create customized student profiles that are searchable by recruiters or other college personnel. The Standout® system is described in co-pending U.S. patent application Ser. No. 09/479,271, which is hereby incorporated by reference. In the Standout® system, a prospective applicant completes and submits over a computer network an electronic form that includes multiple fields of information. The information in the form is stored in corresponding fields of a database. An authorized user, such as a college recruiter, searches the database to identify prospective applicants having desired characteristics. Thus, the Standout® system provides a system by which institutions can search through a pool of prospective applicants to locate qualified individuals and by which prospective applicants can present themselves to the institutions. The Standout® database is continually updatedwith saline/fibroblast cells or stem cells. After dosing, the needle was removed without any flush and the CCA was closed with sutures to prevent any bleeding, and the skin wound reclosed with surgical clips. NCS‐01 cell doses ranged from 7.5 × 10^4^ to 3.75 × 10^7^ total in 0.1 to 5 mL with 7.5 × 10^6^ cell/mL concentration. In subsequent studies, the ICA route was vis‐à‐vis compared with IV administration (via the jugular vein).

### 2.2.4. Behavioral tests {#sct312629-sec-0015}

All investigators testing the animals were blinded to the treatment condition. Each rat was subjected to a series of behavioral tests to reveal motor and neurological performances at different time points before and after stroke and transplantation of NCS‐01 cells. The tests included the modified Bederson neurological test (composite score of contralateral hind limb retraction, beam walking


the same fixative for 72 hours, followed by 30% sucrose in PB until completely sunk. Series of coronal sections were cut at a thickness of 40 μm using a cryostat and stored at −20°C. Brains were harvested and coronal sections were collected at a thickness of 2 mm using a brain matrix.

Staining for human mitochondria‐positive cells was conducted on every 1 of 6 sections, 40 mm thick in brain. All sections were washed three times for 5 minutes in PBS. Sections were incubated with saline sodium citrate solution at pH 6 for 40 minutes at 80°C for antigen retrieval. Next, samples were blocked for 60 minutes at room temperature with 8% normal goat serum (Invitrogen, California) in PBS containing 0.1% Tween 20 (PBST; Sigma). Sections were then incubated overnight at 4°C with mouse anti‐HuMitoto host cells produced the largest increases in rescue of host cell death, with all at least 20% greater than their OGD controls (*P* \< .05, *P* \< .01, *P* \< .0001) (Figure [1](#sct312629-fig-0001){ref-type="fig"}C). No significant difference was observed between these three higher doses. The greatest increase was found in the 200% NCS‐01 cell wells, which were approximately 35% greater than the OGD control (*P* \< .0001). In addition, MTT assay revealed a similar pattern (Figure [1](#sct312629-fig-0001){ref-type="fig"}B,D). Dosages of 25%, 50%, 75%, 100%, and 200% NCS‐01 cells produced approximately onefold increments in MTT absorbance over 0% NCS‐01 cells or OGD controls (*P* \< .01, *P* \< .001, *P* \< .0001). The 400% NCS‐01 cell wells exhibited the most benefit, displaying a twofold increase in mitochondrial activity over the OGD control (*P* \< .0001).

![NCS‐01 cells protect cultured primary rat cortical cells against oxygen glucose deprivation


the stroke model when compared to the no infusion group and the saline group (Figure [2](#sct312629-fig-0002){ref-type="fig"}C). This suggests that ICA administration of NCS‐01 cells may be just as safe as no infusion, when operationalized by CBF assessment.

### 3.1.4. Doses as low as 7.5 × 10^5^ NCS‐01 cells substantially reduce infarct volume and improve neurological function {#sct312629-sec-0024}

Based on the previous measures, it was determined that ICA administration is the better route than IV to deliver more cells to the target lesion. This measure also found a benefit of NCS‐01 cells for neurological function and infarction volume in MCAO rats. To further advance these findings, cell dosages were evaluated using the ICA administration. In the first investigation, groups of six rats were subjected to 1 hour transient MCAO and were given 7.5 × 10^5^,NCS‐01 cells rescue ischemic cells in a dose‐dependent manner in the OGD model. Consequently, we observed upregulated levels of bFGF and IL‐6 in the supernatant of cultured NCS‐01 cells, implicating therapeutic molecule secretion as a mechanism mediating the cells\' functional effects. in vivo results showed that ICA cell delivery produced a significant dose‐dependent reduction in infarct size more effectively than IV, possibly due to its capacity to deliver more cells, and likely therapeutic molecules, into the ischemic brain. The effective dosage was 7.5 × 10^6^ cells in 1 mL. The ICA cell delivery route was safe as evidenced by no observable alterations in the CBF and absence of microembolic events.

The second study was designed to assess the disease condition (transient or permanent MCAO) and therapeutic window in the in vivo


of filopodia of cultured neural precursor cells, while in vivo accelerates the transendothelial migration and facilitates the invasion of certain perivascular sites.[45](#sct312629-bib-0045){ref-type="ref"} Filopodia formation and cell motility, especially transendothelial migration, may be facilitated by adhesion molecules, such as Ninjurin 1,[46](#sct312629-bib-0046){ref-type="ref"} and transcription factors, including serum response factor.[47](#sct312629-bib-0047){ref-type="ref"} Understanding the putative role of these transmembrane glycoproteins, adhesion molecules, and regulatory factors may improve filopodia formation, as well as the resulting therapeutic outcome of NCS‐01 cells in stroke.

Stroke is one of the main causes of disability among adults worldwide, with risk factors such as aging, hypertension, hyperglycemia, diabetes mellitus, and obesity.[48](#sct312629-bib-0048){ref-type="ref"}, [49](#sct312629-bib-0049){ref-type="ref"} The only FDA‐approved drug is tPA with limited treatment window and high risk of hemorrhagic transformation; hence, there is a significant need for finding a novel treatment fornumber of stroke patients ranging from time of admission to days during poststroke stabilization. We also demonstrated that NCS‐01 cells are beneficial for either transient or permanent occlusion MCAO paradigms. This supports the use of NCS‐01 cells even for stroke patients who might have missed the opportunity to receive revascularization procedures such as tPA or endovascular interventions. Finally, we provided mechanism‐based evidence that NCS‐01 cells released significantly higher levels of cytokines bFGF and IL‐6, clearly distinguishing them from routinely harvested MSCs. The pioneering observation of formation of long processes of filopodia extending from NCS‐01 cells toward ischemic cells opens new avenues of research for engineering stem cells designed to propel cell processes to bridge the gap between normal and pathologic (ie, ischemic) tissues. Because the ischemic tissue limits


The inventor named herein has in the past invented numerous flexible structures employing a variety of resilient pole members and arrangements. Some of these are shown and described in U.S. Pat. Nos. 3,863,659; 3,986,519; 4,099,533; 4,265,260; 4,265,259; 4,414,993; 4,706,696; and 4,944,322.
Typically, the resilient pole members employed are constructed of aluminum, graphite, or similar resilient materials. Both one piece and segmented pole members are known. One piece pole members have the advantage of strength and ease of assembly. However, segmented pole members have the advantage that they can be disassembled and compactly stored, which may be important in certain applications, such as lightweight backpacking tents.
Typically segmented pole members have the segments connected end to end, for example using a male-female connection and a friction fit. Hub connections are alsobe that these words are not often used while speaking, but that is not the same thing as saying "no one ever actually uses these". If that was true, I would expect Cambridge, Collins, and Merriam-Webster to put "archaic" beside them. They haven't done that. I will just list some examples for "irascible" from some reputable sources:

Sanders, an irascible Northeastern liberal, was never a natural fit with many black voters ... - The Washington Post, March 25, 2020.
It was also Trump at his most defensive and irascible. - The Washington Post, March 19, 2020.
Nick Nolte is the irascible Western University coach based ... - USA Today, March 9, 2020.
Trump never pivots to maturity and never meets the occasion; he only exhibits irascible consistency. - NBC News, March 24,


#!/bin/bash
# Copyright (C) 2017 The Android Open Source Project
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# Licensed under the Apache License, Version 2.0 (the "License");
# you may not use this file except in compliance with the License.
# You may obtain a copy of the License at
#
#      http://www.apache.org/licenses/LICENSE-2.0
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# distributed under the License is distributed on an "AS IS" BASIS,
# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
# See the License for the specific language governing permissions and
# limitations under the License.

CMD="gn"
source "$(dirname "${BASH_SOURCE[0]}")/run-buildtools-binary.sh"
are both orthogonal (or unitary) matrices, the rank of R is the same as the rank of A.  To bring up the rank of A, we just need to find ways to increase the rank of R; and this is much more straight forward thanks to the structure of R as the result of pivoting and the fact that it is upper-triangular.
Now, with the requirement placed on pivoting procedure, if any diagonal element of R is 0, the entire row has to be 0.  The n-rank(A) rows of 0s in the bottom if R is responsible for the nullity.  If we replace the lower right corner with an identity matrix, the that new matrix would be full rank.  Well, we cannot really do the


be the second derivative of h(t). Find the first derivative of a(l) wrt l.
8*l**3
Suppose 185*k - 180*k = 45. What is the derivative of -k*x - 6 - 40*x**4 + 1 + 9*x wrt x?
-160*x**3
Let z(h) = -169*h**3 - 5*h**2 - 6*h - 76. Let w(l) = -170*l**3 - 4*l**2 - 5*l - 78. Let t(j) = -5*w(j) + 4*z(j). What is the second derivative of t(p) wrt p?
1044*p
Let m be (-3)/((-55)/(-30) - 2). Let b = 25 - m. Find the second derivative of -10*n + 4 - 4 + b*n**4 wrt n.
84*n**2
Find the third derivative of 23*b**4 - 69*b**2 + 101 - 101 wrt b.
552*b
Let x(q) = -5*q + 13. Let v be x(-18). Differentiate 6*y - 71 + 24*y + v - 65 with respectthat there are legislators who "feel it's not necessarily what their focus is, but they feel that if it came to a floor vote, they would support it," Miller said. "That group of people has expanded every year."

Attorney General Peter F. Kilmartin has launched an aggressive anti-legalization campaign, which Miller says is spreading misinformation about legalization. "I warned him that the data they're using is inaccurate,” the Senator said. “I feel that his presentations to cities and towns [have] veered off from being totally accurate on what the legislation intends to do."

The current bill would allow cities and towns to block certain kinds of marijuana businesses, essentially allowing towns opposed to marijuana to opt out of the recreational market. Miller said that Kilmartin has failed to accurately explain


one thing, Simpson consistently has made claims of being a longtime, and fairly high-level, Republican activist in Alabama. But my Republican sources in Alabama say they either don't even know her or barely remember her having done some rather low-level volunteer work. On Friday, longtime activist Toby Roth said of the 2002 campaign (around which most of her allegations revolve): "I was the campaign director [for now-Gov. Bob Riley, who challenged Siegelman]. I did not know her. Never met the lady." His only contact with her, he said, came four years later when she faxed him letters demanding that one of her clients be awarded a state contract to clean up a tire dump. The contract went to somebody else, and Roth says her bizarre allegations began surfacing1993 and Casuga seeks review of the Board's decision here.

5
Summary disposition of an appeal is appropriate when the position of one of the parties is clearly right as a matter of law so that there can be no substantial question as to the outcome of the case.   See Groendyke Transport, Inc. v. Davis, 406 F.2d 1158, 1162 (5th Cir.1969).  This is such as case.  Issues settled by a prior decision may not be relitigated.   Spears v. Merit Sys. Protection Bd., 766 F.2d 520, 523 (Fed.Cir.1985).  In this case, Casuga is attempting to have his claim relitigated a third time.

6
Accordingly,

IT IS ORDERED THAT:

7
(1) OPM's motion for summary affirmance is granted.

8
(2) Each side shall bear its own costs.


Q:

Late followup for Internship Opportunity

About a week and a half ago I received an email from a mentor with whom I'd previously inquired about internship opportunities, informing me of possible projects I could join. I accidentally let it slip for a bit and responded after 4 days. It's been almost a week since - how should I go about following up? I'm really punching myself in the gut, this was perhaps my "dream" work per se.

A:

Simple enough to just ask. Ask if the offer is still open and what your next steps should be. And express your enthusiasm as you have here.
Four days isn't actually that long. Nor is a week without a reply. But if it is upcoming soon then an email now should be fine.ischemia/reperfusion. The expression of tTG in PECAM-1-immunoreactive blood vessels may be associated with integrin regulation or transendothelial migration of leukocytes in the ischemic CA1 region. In this study, we also observed the effect of cystamine, a tTG inhibitor, against ischemic damage. Administration of cystamine protected in certain degree neuronal damage from ischemic damage in the CA1 region. These results suggest that tTG may be associated with neuronal death in the hippocampal CA1 region induced by ischemia/reperfusion.


ChangeCount { get { return Changes != null ? Changes.Count : 0; } }
    public bool hasChanges { get { return Changes != null ? Changes.Count > 0 : false; } }

    public void SubmitChanges()
    {
        _dataContext.SubmitChanges();
        if (ChangeCount > 0)
        {
            Changes.ForEach((item) => item.Value.Invoke());
            _dataContext.SubmitChanges();
        }
    }
    public void CancelChanges()
    {
        ifHorford (42) acknowledges the crowd after a video following the first quarter of the Celtics game against the Atlanta Hawks at Philips Arena. Jason Getz-USA TODAY Sports

Jan. 8: Houston Rockets guard James Harden reacts after losing control of the ball in a collision with Toronto Raptors guard Cory Joseph in the first half at Air Canada Centre. Dan Hamilton-USA TODAY Sports

Dec. 27, 2016: Rockets forward Nene, right, exchanges heated words with Mavericks guard Justin Anderson, center, during the first half in Dallas. Both players were assessed technical fouls, and the Rockets won 123-107 as the team piled up eight technicals and two flagrants. Kevin Jairaj, USA TODAY Sports

Dec. 26, 2016: Mavericks defender Salah Mejri (50) fouls Pelicans forward Anthony Davis (23) on a drive to the hoop during


spend on upgrading their stadium, on buying players, on training grounds, and on making their club better.

But there’s a second league above this League. A super league if you will. And unlike the League, it’s not friendly, things aren’t shared equally, and there are no parachute payments for relegated teams. It is pure capitalism: the rich get richer, the poor get poorer, and the have-nots are left to rot in the gutter.

Unlike the League, there are 32 teams from the leagues all over Europe and there is no egalitarian home and away play round robin to decide the winners and losers. Teams are only guaranteed 6 games and £6m. In those six guaranteed games there are bonuses that go to teams who win (£700,000 per) or even draw(£350,000 per). Those six games are used to determine who will go into the next round with the top two teams from each group selected to the round of 16. After that, it’s a knockout competition.

Making it to that round of 16 guarantees an additional £2.64m. That round’s prize money alone is more valuable than winning the FA Cup.

The next round is worth £3.3m.

The next round is worth £3.7m.

And if you win, the prize is £7.9m.

The total prize money up for grabs is £363,440,000. But there’s a hidden prize. One more valuable than the prize money. And completely determined by how powerful your league is. This is what this “Champions League” refers to as the “Market Pool”.

That Market Pool prize money is worth £300m and nearly 25% of


= 10*m - 68. Let r be f(5). Is -98*45/r - (0 + 0) a multiple of 49?
True
Let h(i) = -27*i - 688. Is h(-45) a multiple of 18?
False
Suppose 2*o = 6*o + 4, 5*o = -5*s + 70. Does 3 divide s?
True
Let z(l) = 4*l**2 - l. Let p be z(-1). Suppose -p*v - 5*j = -25, -4*j - 32 = -2*v + 2. Suppose 39 - v = 5*x. Is 4 a factor of x?
False
Let p = 35 - 39. Let d(n) = 3*n**2 - 5*n - 2. Does 32 divide d(p)?
False
Let s be 78/36 - (-2)/(-12). Suppose -a = w + s*a - 2253, 3*w + 2*a - 6766 = 0. Does 29 divide 3/1 - w/(-16)?
False
Suppose 0 = 12*u - 3329 - 775. Does+ x. Is v even?
False
Let r(b) = -2*b**2 + 5*b - 12 + 8*b**2 + 8*b - 7*b**2. Is r(5) a multiple of 3?
False
Let z be (0 + -1)*1 + 3. Suppose -5*a = 3*b - 47, z*b - a = 6*b - 57. Is b a multiple of 7?
True
Let w(t) = -t**3 + 10*t**2 - 6*t + 8. Let x be w(11). Let q = x - -94. Does 25 divide (-6)/(-5)*q/(-2)?
False
Let z(q) = 4 + 1 - 3*q + q - q. Suppose u = -2*u - 15. Is z(u) a multiple of 10?
True
Let f = 629 + -560. Is f a multiple of 14?
False
Suppose 2*p - 3*p = 0. Suppose 0 = -p*a - 2*a + 52. Suppose -a - 106 = -4*o. Does 22


3*s + 5*i - 38. Does 8 divide s?
False
Let p(w) = -w**2 + 9*w - 4. Let s(t) = 8*t + 7. Let v(y) = -7*y - 6. Let n(z) = -6*s(z) - 7*v(z). Let q be n(7). Does 6 divide p(q)?
False
Suppose -31 = 4*t - n, n - 25 = 6*n. Let l(v) = -v + 11. Is l(t) a multiple of 20?
True
Let k(j) = 19*j**2 + j - 28. Is k(3) a multiple of 39?
False
Let l(x) = -36*x + 61. Does 19 divide l(-2)?
True
Is (9/((-135)/(-50)))/((-3)/(-162)) a multiple of 3?
True
Let g(n) = n**2 - n. Let f(b) = -b**3 - 2*b**2 - 15*b - 4. Let i(y) = f(y) - 3*g(y). Is i(-4) a multiple of 4?
True
Suppose -13*q = -3042 - 8970. Is 11 a factor of  /// The district, state, or province where the resource is located.
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        public string LocationDataDistrict { get => ((Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdatePropertiesInternal)Property).LocationDataDistrict; set => ((Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdatePropertiesInternal)Property).LocationDataDistrict = value; }

        /// A canonical name for the geographic or physical location.
        [Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Origin(Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.PropertyOrigin.Inlined)]
        public string LocationDataName { get => ((Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdatePropertiesInternal)Property).LocationDataName; set => ((Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdatePropertiesInternal)Property).LocationDataName = value; }

        /// Internal Acessors for Identity
        Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdateIdentity Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.IMachineUpdateInternal.Identity { get => (this._identity = this._identity ?? new Microsoft.Azure.PowerShell.Cmdlets.ConnectedMachine.Models.Api20200802.MachineUpdateIdentity()); set { {_identity = value;} } }


The molecular pathogenesis of fully virulent, wild-type Y. pestis in relevant animal models has been relatively neglected because of the scarcity of secure BSL-3 facilities and trained personnel certified to work with this Class A select agent. The threat of bioterrorism and the emergence of multiply-antibiotic resistant strains of Y. pestis increases the urgency for a more detailed understanding of the host-pathogen relationship at the molecular level that may lead to the design of improved medical countermeasures and diagnostics. We have established mouse and rat models of bubonic plague that incorporate flea-to-rodent transmission to investigate the role of specific Y. pestis virulence factors and to characterize the host response to naturally acquired infection. We have characterized the kinetics, microbiology, and histopathology of bubonic plague in rats following intradermal  } else {
        return inverse(this);
      }
    } else {
      if (options.data && options.ids) {
        let data = createFrame(options.data);
        data.contextPath = appendContextPath(options.data.contextPath, options.name);
        options = {data: data};
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      return fn(context, options);
    }
  });
}


crankcase ventilation. The moisture contained in the air in this case can condense on the intercooler, whereupon ice can form.
The object of this invention is to make available a process for operating an internal combustion engine in order to be able to easily detect such an icing state of the intercooler and eliminate it by countermeasures.7?
False
Suppose y + y = 3*o + 307, 4*o + y = -424. Let z be (-45)/o + (-108)/7. Which is greater: -14 or z?
-14
Suppose 0 = -k + 1 - 2. Let u = k - 0. Which is bigger: u or -3/7?
-3/7
Let d(q) = -2*q + 7. Let f be d(4). Suppose 4*u - 9 = -1. Let h be (u - 4) + 36/19. Which is greater: f or h?
h
Let t(i) = -3*i**2 - 2*i - 1. Let y be t(-1). Are 1/4 and y equal?
False
Let p(l) = -l**2 - 6*l - 3. Let w(o) = -2*o**2 - 12*o - 6. Let g(j) = -7*p(j) + 4*w(j). Let y be g(-4). Are 5 and y equal?
True
Suppose 3*r + 14 = 5*d - 0, -d +


3*l - 18 = 0. Suppose 0*d = -2*d - v. Is -4 smaller than d?
True
Let t = 5713/7 - 814. Which is bigger: t or 1?
t
Let m be -1 + ((-2)/6)/1. Let k = 0 - -13. Let n = 13 - k. Which is smaller: n or m?
m
Let a = -0.086 + -0.014. Is 40/9 >= a?
True
Suppose -5*u = -3*u + 10. Let o = 7 + u. Which is bigger: 1 or o?
o
Suppose b - 8*b + 14 = 0. Is b smaller than 1?
False
Let x be 0*(-1)/(-2) + 2. Let w(r) be the third derivative of r**6/120 + r**3/6 - r**2. Let t be w(1). Is x bigger than t?
False
Let q(i) = i - 6. Let x be q(4). Let d be 2/12*10 -World Cup champion. Today I got nipped by the overall World Cup sprint leader. I'm in good company right now."

Sweden's Emil Joensson won Stage 3 while Tour leader Dario Cologna of Switzerland finished third. Kershaw now sits less than four seconds behind the Swiss skier in overall time. Alexander Legkov of Russia is third overall almost 20 seconds behind Kershaw.

Canadians on top

The back-to-back silver medals for the Sudbury, Ont., native are even more impressive considering the diversity of the events: Saturday's was a distance race and Sunday's a sprint.

It was a good weekend for his teammate Alex Harvey as well. The 22-year-old finished third in his heat and seventh overall to move him up to fourth in overall standings.

"It was a good surprise for me today," said Harvey,


be expanded to more than two players. Montmort \[([-@e17]), pages 186–187\] originally described the problem for four players and posed the question: What are the chances of each player relative to the order in which they make their play?

Because of the winning conditions, it is obvious that one would want to switch low cards and keep high ones. The key is to find what to do with the middle cards, such as seven and eight, when two players are playing the game. In other cases, cards are clearly too low to keep or too high to switch, being much below or above the average in a random draw. Naturally, the threshold would be lower with more than two players.

In Part V of *Essay d’analyse*, only the game withof a singular nature.

In a postscript to this letter, Montmort makes an additional remark:

> As there are few copies of my book left, there will soon be a new edition. When I have decided, I will ask you permission, and your uncle, to insert your beautiful letters which will make the principal embellishment.

It is this announcement that may have motivated Nicolaus Bernoulli to continue his correspondence with Montmort and to send him much interesting material. Publishing mathematical material outside a scientific society or without a patron to cover the costs was an expensive proposition, one that Montmort could afford. Because of the specialized type that was used and the accompanying necessary skill of the typesetter, the cost of a mathematical publication was well above the norm for less


Hald ([-@e12]), page 318. None of the parties in this debate actually explain their calculations. Waldegrave’s probabilities are justified in Todhunter ([-@e21]), pages 107–110; the Bernoulli–Montmort probabilities are in Hald ([-@e12]), pages 315–318. The difference in the probabilities is that Waldegrave’s probabilities are conditional on Paul having a seven in his hand and the Bernoulli–Montmort probabilities are the marginal probabilities for all cards that Paul may hold.

In a letter dated June 2, 1712, Bernoulli replies to Waldegrave’s argument by accusing him of committing a fallacy. He argues that if we suppose that $A$ leads Paul to switch with a seven, and so leads Pierre to switch with an eight (if Pierre knows Paul switches with seven), then it also leads Paul to hold on to a seven. Therefore,(here and now) is the principal question: the calculation does not teach us anything about that, and I take this decision to be impossible.

Thus, Montmort believes, it seems, that there is no optimal probability allocation.

But he has another reason for believing that the solution of the game is impossible. He has in mind the game Les Étrennes ([@e18], pages 406–407). Montmort also believes that it is impossible to prescribe any strategy of play in Les Étrennes because the players might always try, and indeed good players will try, to deceive other players into thinking that they will play something they are not playing, thus trying to outsmart each other (“jouer au plus fin” is the phrase used in French).

As he was finishing his letter, Montmort received one from


his general solution). Montmort replied on March 22, 1715, that he agrees with Bernoulli’s assessment. On returning from a trip to England, Montmort reported to Bernoulli in a letter dated June 8, 1715, that one of Bernoulli’s solutions to the problem of the pool had just been printed in the *Philosophical Transactions* (Bernoulli, [-@e07]). Bernoulli had sent De Moivre two solutions; De Moivre claimed he had found an error in the first solution.

Waldegrave Identified
=====================

Many in the past have tried unsuccessfully to identify the Waldegrave who solved the problem of Le Her and who suggested the problem of the pool, often called Waldegrave’s problem. @e02 reviewed these attempts at identification and narrowed the field down to Charles, Edward or Francis Waldegrave, the three brothers of Henry Waldegrave, 1st Baronof Le Her, he says, “although I first found the determination of the numbers $a$ and $b$, $c$ and $d$…” Montmort’s suggestion of priority could have come about as a result of a conversation between Waldegrave and Montmort, with Waldegrave putting pen to paper. This illustrates Fasolt’s ([-@e10]) claims about the limits of history. Our data from the past is what has been written, not what has been spoken. Further, we can never know the tone behind what was written, such as Bernoulli’s apparently nasty comments to Montmort about De Moivre in his letter of April 14, 1714. Instead of coming up in conservation, Montmort may be claiming priority because he found the general formula in $a$, $b$, $c$ and $d$; the numbers were only a special case.


trivet in the Instant Pot.

Place the mason jars on the trivet.

Loosely cover the mason jars with a piece of aluminum foil, to prevent condensation from dripping in the brownies.

Close the Instant Pot lid, and make sure the steam release handle is in the ‘Sealing’ position.

Press ‘Manual’ (or ‘Pressure Cook’) and ‘+’ or ‘-‘ until display reads ’20’ (20 minutes).

Instant Pot display will change to ‘On’.

Once the Instant Pot is pressurized, the float valve will go up.

The display will count down from 20 to 0; it will switch to ‘Keep Warm’ mode and display ‘L0:00’.

Do a Quick Release: move the steam release handle to ‘Venting’. I like to place a folded towel over the steam release handle and move it to the venting position. Remove the towel after turningfor which I'd like to be the answers about? Or should I rather leave that open, so that where needed in the answers an indication about the platform is included?
What kind of tags might be relevant (such as mainframe-alternatives)?
Imagine a question doesn't include such indication, with answers like "if I would be asked this question in a mainframe environment, then this is what my answer would be", is that to be encouraged, or rather discouraged?

A:

Personally, if I am knowledgeable in multiple ways to solve a problem, I will attempt to articulate them all, depending on the depths I need to go into for each answer this might be to multiple questions.
Equally, if someone has responded to the question for Product X and I can answer it for Product


a TeV cosmic ray source for the first time. Further data analyses of current experiments will certainly provide important information, like whether one can detect a small anisotropy and its direction. Eventually, future experiments, both on the ground (K. Mannheim, [pdf](http://irfu.cea.fr/Meetings/TANGOinPARIS/slides/mannheim.pdf), [mp4](http://irfu.cea.fr/Meetings/TANGOinPARIS/videos/mannheim.mp4)) or balloon borne and spatial detectors (L. Derome, [pdf](http://irfu.cea.fr/Meetings/TANGOinPARIS/slides/derome.pdf), [mp4](http://irfu.cea.fr/Meetings/TANGOinPARIS/videos/derome.mp4)) will certainly offer the opportunity to have a deeper look into this problem.

We would like to warmly thank all the TANGO in PARIS speakers, as well as the members of the organizing committee: F. Aharonian, O. de Jager, R. Mohayaee, P. Serpico and J. Silk. We acknowledge the Institut d’Astrophysique de Paris, ANR, IPhT/ CEA Saclay, Irfu/CEA Saclay, GdR Terascale and GdR PCHE for their support.

All citations refer to the TANGO in PARIS talk (and references therein)genes genome-wide, they show a modest but significant difference in per-gene d*N*/d*S* compared with genes not yet associated with any rare disease ([Supplementary Figure 1](#xob1){ref-type="supplementary-material"}). These data support the idea of disease genes being more likely to be missense-depleted in the population data. When we analyse known disease genes by disease inheritance pattern, we find that genes causing autosomal dominant or X-linked conditions have significantly lower genic d*N*/d*S* compared with those causing recessive conditions ([Figure 1](#fig1){ref-type="fig"}). These results suggest selection against missense variants can be seen in disease genes and seen more significantly in genes where a single-allele deleterious variant is sufficient to lead to a significant phenotype. Given the large portion of exome diagnoses that result from dominant/*de novo* variation,^[@bib10; @bib11; @bib12]^ applying missense depletion in prioritising


ranked poorly however by overall missense depletion, at 451st rank, compared to *ARF1* or *SOD1*. Homozygous, mitochondrial and X-linked variants were also considered, but these variants either were found previously in controls or the genes did not rank highly by missense depletion or EMD.

To further examine missense variants in *ARF1* and *SEPT7,* variant locations from the patient exome were examined on variant distribution plots from population exome data (to assess overlap with MDRs). The proband\'s missense variant in *SEPT7* did not co-localise with the distal MDR in *SEPT7* and was in a region of frequent population missense variation. In contrast, the proband\'s *ARF1* missense variant (c.103T\>C (p.Y35H) NM_001024226) corresponded within the population-data-observed MDR of *ARF1* ([Supplementary Table 5](#xob1){ref-type="supplementary-material"}). These results indicate that *ARF1* demonstrates missense depletion in populationinheritance categories also yielded comparable results in missense depletion analyses.

Exome data analysis in undiagnosed patients
-------------------------------------------

Exome sequencing was performed using blood samples from individuals after informed consent. Studies were performed under The UCSF Committee for Human Subjects Research. Genomic DNA was extracted and sequencing performed using Illumina HiSeq2500 following exon capture. Following QC and duplicate marking, variants were aligned to reference and variants called using GATK. Variants were filtered for amino-acid alteration and then for \<1% minor allele frequency based on ESP, NIEHS EGP and the Hapmap project. For proband analysis, all variants meeting these criteria were examined using missense depletion methods regardless of if the variant/gene had previous annotation. Following addition of parental exome data, trio analysis was also performed and *de novo*, compound heterozygous and inherited heterozygous


v;

    tu = mad(t, mad(t, mad(t, mad(t, pp4, pp3), pp2), pp1), pp0);
    tv = mad(t, mad(t, mad(t, mad(t, qq5, qq4), qq3), qq2), qq1);
    u = absx < 0.84375f ? tu : u;
    v = absx < 0.84375f ? tv : v;

    v = mad(t, v, 1.0f);
    float q = MATH_DIVIDE(u, v);

    float ret = 1.0f;

    // |x| < 6
    float z = as_float(ix & 0xfffff000);
    float r = exp(mad(-z, z, -0.5625f)) * exp(mad(z-absx, z+absx, q));
    r = 1.0f - MATH_DIVIDE(r,  absx);
    ret = absx < 6.0f ? r : ret;

  r = 8.45062911510467529297e-01 + q;
    ret = x < 1.25 ? r : ret;

    q = x < 0x1.0p-28 ? 1.28379167095512586316e-01 : q;

    r = fma(x, q, x);
    ret = x < 0.84375 ? r : ret;

    ret = isnan(x) ? x : ret;

    return y < 0.0 ? -ret : ret;
}

_CLC_UNARY_VECTORIZE(_CLC_OVERLOAD _CLC_DEF, double, erf, double);

#endif


looking for Jeff and

Aaron, and spotted their car parked near an unknown house. Tellegen parked the car around

back and approached the house. Jeff and Aaron then opened the garage door and told

Tellegen to pull her car into the garage. Once inside, accounts differ as to whether Tellegen

participated in loading the cars with items from the home.

                                             2
¶4     The State filed an information charging Tellegen with accountability for burglary.

The State later withdrew that charge and amended the information to charge Tellegencharging documents give “a

plain, concise, and definite statement of the offense charged, including the name of the

offense, whether the offense is a misdemeanor or felony, the name of the person charged,

and the time and place of the offense as definitely as can be determined.” Section 46-11-

401(1), MCA.

¶9     We have consistently reaffirmed our holding in Tower that accountability is not a

separate or different offense from the one charged, but rather, is “merely a conduit by which

to find a person criminally liable for the acts of another.” State v. Maetche, 2008 MT 184, ¶

16, 343 Mont. 464, 185 P.3d 980; State v. Abe, 1998 MT 206, ¶ 31, 290 Mont. 393, 965

P.2d 882; State v. Tower, 267 Mont. 63, 68, 881 P.2d 1317, 1320 (1994); In