cut. PA1 a caliper feeler and measurement plate to measure for the size of the femoral prosthesis to be received, said caliper feeler and measurement plate adapted to determine a first distance between an anterior surface of the femoral cortex and a plane tangent to a posterior surface of the medial and lateral condyles of a femur, the caliper feeler referencing the anterior surface of the femoral cortex and the measurement plate referencing the plane tangent to the posterior surface of the medial and lateral condyles; PA1 a graduated scale to compare the first distance to at least two standard femoral prosthesis sizes and to determine the smaller of the at least two standard femoral prosthesis sizes; PA1 a graduated scale to measure a second distance between theis required for facilitating mobilization of EPCs into peripheral blood and homing to neovascularization sites. For many years, CXC chemokine receptor 4 (CXCR4) has been considered as the unique receptor of SDF-1 and as the only mediator of SDF-1-induced biological effects \[[@b9], [@b10]\]. However, recent studies reported that SDF-1 was also a ligand of a novel chemokine receptor, CXC chemokine receptor 7 (CXCR7) \[[@b11], [@b12]\]. CXCR7 is widely expressed on haematopoietic system, heart, vascular endothelial cells, bone, kidney and brain \[[@b12]--[@b16]\]. CXCR7 has a significant higher binding affinity for SDF-1 than CXCR4 \[[@b12]\].

The functions of CXCR7 and its molecular interactions in the cells after binding with SDF-1 remain poorly defined. Some studies revealed that CXCR7 functions as a signalling receptor, promoting cell proliferation, adhesion, chemotaxis and activation of


expression positive control. The cell surface expression of CXCR7 and CXCR4 was investigated by flow cytometry (C).](jcmm0015-1299-f2){#fig02}

The effects of CXCR7 and CXR4 on EPC adhesion
---------------------------------------------

The adhesion capacity of EPCs to the activated endothelial cells and the extracellular matrix are very important for EPC participating in angiogenesis \[[@b28]\]. We tested whether SDF-1 promotes EPC adhesion to extracellular matrix or endothelial cells using an *in vitro* cell adhesion assay. As shown in [Figure 3A and B](#fig03){ref-type="fig"}, Both CXCR7 antibody and CXCR4 antibody significantly inhibit SDF-1-mediated EPC adhesion to collagen ([Fig. 3A](#fig03){ref-type="fig"}) and fibronectin ([Fig. 3B](#fig03){ref-type="fig"}). The inhibitory effect of either CXCR7 antibody or CXCR4 antibody was confirmed with either CXCR7 antagonist CCX733 or CXCR4 antagonist AMD3100 ([Fig. 3A and B](#fig03){ref-type="fig"}). Although both CXCR4 and CXCR7 antibodies or antagonists could inhibitof these labelled EPCs to HUVEC monolayer, but pre-treatment of these EPCs with anti-CXCR4 antibody or AMD3100 had no such significant effect ([Fig. 3C](#fig03){ref-type="fig"}). It is worth mentioned that the inhibitory effect of blocking both CXCR7 and CXCR4 either with their antibodies or antagonists are similar to that of blocking CXCR7 alone ([Fig. 3C](#fig03){ref-type="fig"}). These results thus suggested that both CXCR4 and CXCR7 are essential for SDF-1-mediated EPCs adhesion to extracellular matrix, whereas SDF-1 mediates adhesion of EPCs to endothelial monolayer only *via* CXCR7.

Requirement of CXCR4, but not CXCR7, for the migration of EPCs
--------------------------------------------------------------

The chemotactic activity of SDF-1 on EPCs was evaluated *in vitro*. SDF-1 induced the migration of EPCs in a dose-dependent manner, and 10--100 ng/ml SDF-1 can significantly induce the migration of EPCs ([Fig. 4A](#fig04){ref-type="fig"}). Pre-treatment


for three of the toxins, metabolic patterns also disclosed an enhanced activity of the glycerol phosphate shuttle inferring the inhibition of NADH dehydrogenase at complex I. Secondly, inhibition of the electron transport was accompanied by a limiting availability of citric acid cycle intermediates and aspartate. Concomitantly, specific perturbations of the purine nucleotide cycle were observed. We have shown here that metabolomic approaches may assist to predict complex modes of action of toxic compounds on cellular level as well as to unravel specific dysfunctions in the energy metabolism.Selachian

Residing in deep oceans and great seas, the Selachians, sometimes called Shark-people, evoke fear and wonder. Many Selachians aren’t even native to the Material Plane. They hail from a world beyond—from the endless expanses of the Elemental Plane of Water. They are a very varied people, and when not in isolation, work by the sea as sailors, pirates, and merchants, always longing for their independence.

Fins and Gills

From above, Selachians may look much like regular sharks. Only when surfacing to seize a prey or for meeting an individual does their humanoid appearance reveal itself.

Although different subraces may present some differences in appearance, all of them are covered by a thick hide and posses fins stretching from their lower necks. Their color varies from subrace to subrace, but most posses


95% CI = 0.05--4.02), 25--27 (*β* = 3.77, 95% CI = 1.36--6.18) and 28--30 (*β* = 2.39, 95% CI = 0.53--4.26), compared with ages 13--15. As shown in [Figure 1](#nutrients-10-01585-f001){ref-type="fig"}, the score for "meat, poultry, fish, and eggs" was consistently low across the age categories, primarily due to intakes above the recommended values. The fruit score remained low across the age categories and sexes due to low intakes. There was more variation observed in the sweets score, which is reverse-scored such that a higher score represents low sweet consumption ([Table S1](#app1-nutrients-10-01585){ref-type="app"}), with different patterns observed in males and females. While the fats and oils score appeared high (reflecting low intakes), this may be due to lack of inclusion of fats and oils reported as part of composite dishes144.5 (117.6--171.3)          160.6 (139.3--182.0)
  Vegetables (g/day)                        205.9 (196.9--214.9)                                                            222.3 (212.8--231.8) \*     246.8 (226.3--267.3) \*\*\*   260.2 (231.9--288.6) \*\*\*   251.5 (231.6--271.4) \*\*\*   260.2 (242.6--277.9) \*\*\*


  14.7 (12.9--16.6)           22.5 (16.8--28.3) \*          15.5 (11.2--19.7)             21.2 (16.9--25.4) \*\*        15.9 (12.5--19.3)
  Oils (g/day)                              6.94 (6.23--7.66)                                         algo_params ? algo_params : ""));

      if(key)
         {
         *key_obj = new botan_privkey_struct(key.release());
         return BOTAN_FFI_SUCCESS;
         }
      else
         {
         return BOTAN_FFI_ERROR_NOT_IMPLEMENTED;
         }
      });
   }

int botan_privkey_load(botan_privkey_t* key, botan_rng_t rng_obj,


    const uint8_t bits[], size_t len,
                       const char* password)
   {
   BOTAN_UNUSED(rng_obj);

   *key = nullptr;

   return ffi_guard_thunk(__func__, [=]() -> int {
      Botan::DataSource_Memory src(bits, len);

      std::unique_ptr<Botan::Private_Key> pkcs8;

      if(password == nullptr)
         {
         pkcs8 = Botan::PKCS8::load_key(src);
         }
      else
         {
        up major suppliers like Qatar or Norway to send supplies to Europe.

Meaningless Buzzword

I work on energy policy for a national security think tank, so I am often asked to talk about energy security. Last week, I participated in a conference in which we were asked to comment on “U.S. Energy Security: How Do We Get There?” As I listened to the presenters at the conference, I realized that how you viewed the problem of ‘Energy Security’ depends on how you identify it. We all seem to have determined that energy security is a problem, but we each had different understandings of what the term ‘energy security’ actually means! Of course, that means there were very different prescriptions for how to ‘solve’ the problems of ‘energy security.’

In the absence


either the pseudo wild type (PR*^pse^*) or the NL4-3-derived (PR*^NL^*) protease backbone were analyzed (Figure [3](#F3){ref-type="fig"}, left). H69 is a surface residue on the mature protease, but we recently reported that alterations of H69 modulate precursor structures and thus influence protease autoprocessing and the subsequent Gag processing \[[@B14],[@B24]\]. For example, PR*^pse^*H69E was defective for Gag processing in VLPs produced from cells that were transfected with PR*^pse^*H69E proviral DNA, whereas H69Q had minimal impact \[[@B24]\]. Here, we also found reduced autoprocessing in cells transfected with the PR*^pse^*H69E fusion precursor as indicated by the accumulation of the full-length precursor compared to the wild type (PR*^pse^*) and H69Q controls (Figure [3](#F3){ref-type="fig"} lane 7-9). In addition, the wild type PR*^pse^*mature protease was undetectable but HA-tagged mature H69E protease was identified in thethe two authentic cleavage sites was also observed in this report. The proximal cleavage site was preferentially processed by the PR*^pse^*precursor whereas the PR*^NL^*precursor cleaved the distal site more frequently. A simple interpretation would be that the two proteases have different substrate preferences because amino acid sequences at the cleavage sites are identical in the two precursors. A previous study demonstrated that both sites are cleaved at similar rates by mature protease when added *in trans*to the HIV-1 Gag-PR^D25A^-Pol precursor in an *in vitro*assay \[[@B13]\]. At low concentrations (\~ 0.2 nM), the HIV-1 Gag-Pol precursor preferentially processed the distal site \[[@B6]\]. Therefore, the result of our PR*^NL^*precursor is consistent with the previous reports further validating it as a model system for HIV autoprocessing studies. The PR*^pse^*precursor might fold


cells were collected by centrifugation. For western blot analysis, cell pellets derived from equal volumes of culture medium were directly lysed in SDS/PAGE loading buffer.

Cell culture, transfection and western blotting
-----------------------------------------------

Human embryonic kidney-derived 293T cells were maintained in DMEM (Dulbecco\'s Modified Eagle\'s Medium; Invitrogen, Carlsbad, CA) as previously described \[[@B24],[@B32]\]. For *in vitro*transfection, 293T cells were plated in 6-well plates and incubated overnight to achieve 50-60% confluence at the time of transfection. One hour prior to transfection, chloroquine was added to each well to a final concentration of 25 μM. A total of 1 μg DNA in 131.4 μL of ddH~2~O was mixed with 18.6 μl 2 M CaCl~2~to give a final volume of 150 μl. Then, 150 μl of HBS (50 mM HEPES, 280 mM NaCl, 10 mMstill might be easier to get started with than x86
assembly.

The simulator has the command syntax of

        REG1 REG2

where both REG1 and REG2 are register numbers. This transfers the contents of
REG1 to REG2. By default all registers contain unsigned int values. There are
registers that are mapped to the sum, difference, product, etc. of registers 0
and 1; that's how you do arithmetic and comparisons. Flow control is
accomplished by moving the desired instruction number to REG_PC (register 3).
Input and output (numerical only) is done by moving data to and from REG_IO
(register 4). To store a literal move its value to REG_CONST (register 11; you
can then move it to whatever register you like


float machine
would be hilarious fun. I'm not talking about merely sticking a floating point
copro on a chip, but literally using IEEE 754 on the address bus (obviously
with a bit of rounding) Quad precision floating point should be enough digits
for an address bus to have a heck of a lot of fun with some slack for rounding
issues.

~~~
mietek
> _1) Both this article and reference #3 make claims about not using or
> needing adders to avoid self modifying code, although both implement indexed
> addressing where you take a base address and a offset and er... um...
> argh... ADD them together. So you 're using an adder but playing word
> games._

Your concern is _addressed_ in this paper:

"It would appear that we are cheating slightly by allowing arithmetic in
addresses. However, our "arithmetic" isthe universality of the optical conductivity is well supported by a number of methods up to infrared (IR) frequencies, it has yet remained ambiguous as to whether the *low-energy* approximation breaks down, and the linear band structure and a universal optical conductivity are violated. Presuming that transition from a linear energy dispersion (at IR) to a non-linear one (at UV) occurs smoothly, it is plausible that tangible deviations from the former should begin to appear in the visible regime.

In this regime, the optical response of thin films may be probed by several methods including near-field microscopy, ellipsometry, and transmission/reflection measurements. The use of near-field probes for interrogating visible graphene plasmons is limited due to the interband transitions and high dissipation under conventional doping levels, as highlighted earlier. Moreover,


the Complex Optical Conductivity of Graphene by Fabry-Pérot Reflectance Spectroscopy. *Sci. Rep.* **6**, 34166; doi: 10.1038/srep34166 (2016).

We would like to thank Fianium for generously providing the supercontinuum laser system for the reflectivity experiments as well as Sten Tornegard and Tim Gerke for technical support. We also would like to thank Claudia Ojeda-Aristizabal for providing advice on the SiO~2~ etching. This work is supported by the DOE grant number DESC0004950, DE-SC0012036, and ONR/UMD/AppEl, Task D10, through grant number N000140911190. Partial funding for open access provided by the UMD Libraries' Open Access Publishing Fund.

**Author Contributions** B.G.G. and S.M.A. conceived the idea and designed the experiments. M.Y. and B.G.G. fabricated the devices. B.G.G. and J.T. performed the measurements. B.G.G. analyzed the data. M.S.F. and S.M.A. supervised the project. All authors discussedselect few FileMaker Consultants to be bestowed with the title of FBA FileMaker Platinum Partner. The eXcelisys FileMaker development team has earned this prestigious and valuable precious metal moniker of “FileMaker Platinum Partner” within the FBA through hard work and dedication to being the best FileMaker Pro developers for our clients, the FileMaker Pro community,
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Our FileMaker Pro developers have crafted amazing custom FileMaker Pro database solutionseventdata, handles, varargin)
% This function has no output args, see OutputFcn.
% hObject    handle to figure
% eventdata  reserved - to be defined in a future version of MATLAB
% handles    structure with handles and user data (see GUIDATA)
% varargin   command line arguments to quadratic (see VARARGIN)

% Choose default command line output for quadratic
handles.output = hObject;

% Update handles structure
guidata(hObject, handles);

% UIWAIT makes quadratic wait for user response (see UIRESUME)
% uiwait(handles.figure1);

% --- Outputs from this function are returned to the command line.
function varargout = quadratic_OutputFcn(hObject, eventdata, handles)
% varargout  cell array for returning output args (see VARARGOUT);
% hObject    handle to figure
% eventdata  reserved - to be defined in a future version of MATLAB
% handles    structure


   "LikesCount": null,
    "LikedBy": null,
    "HashTags": {
      "_ObjectType_": "SP.Taxonomy.TaxonomyFieldValueCollection",
      "_Child_Items_": []
    },
    "j33b1bc20532487296f1bbbdead35a56": null,
    "TaxCatchAll$SP.FieldLookupValue$  Array": [],
    "TaxCatchAllLabel$SP.FieldLookupValue$  Array": [],
    "ComplianceAssetId": null,
    "ID$  Int32": 2,
    "Modified": "/Date(1487190160000)/",
    "Created": "/Date(1487190160000)/",
    "Author": {
      "_ObjectType_": "SP.FieldUserValue",
      "LookupId": 12,
      "LookupValue": "xxxxxxxxx",
      "Email": "xxxxxxxxx@xxxxxxxxxx.onmicrosoft.com"
    },
    "Editor": {
      "_ObjectType_": "SP.FieldUserValue",
     life. Just call me SuperWoman. Go ahead. I deserve it.

My best friend and I at Steak and Shake
We both have the same first name. I'm on the left.

What's really amazing about the whole mess is that I got full points for these papers and I ended up graduating with a 4.0 GPA. Not one "B" on my transcript as a graduate student. I know, of course, that companies and libraries are looking for much more than just good grades, but shouldn't it count for something? The graduation ceremony was a lot of fun, mainly because I got to eat out with my best friend, my boyfriend, and my parents, and sister. My best friend couldn't make it to the ceremony, but everyone else was there and I was


the previously reported protocol with modifications.^[@ref17]^ This column consisted of two segments, namely, one 110 cm long blunt end-capillary column and one 40 cm long capillary column with a 15 μm opening tip. To make the blunt end column, we dipped 100 μm ID fused silica tubing into the activated silicate solution (Next Advance, NY), briefly followed by heating to 100 °C on a heater plate for 1 min before the ejection of excess silicate solution. Then, the frit was further heated for another hour at 100 °C and cut to 2 mm in length. The capillary tubing was washed with methanol thoroughly. The blunt end column was then packed with slurry of Magic C18 AQ 200 beads (5 μm) at a concentration of 30 mg/mL in methanol.A bed length of 110 cm was obtained after 6 h of continuous packing at 2800 psi using a Pressure Injection Cell system (Next Advance, NY). The second segment of capillary column was packed similarly to 40 cm in length using Self-Pack PicoFrit column (New Objective, 15 μm tip opening, 100 μm ID, cat no. PF360-100-N-5). Finally, two columns were connected through a metal union with zero dead volume (Upchurch Scientific, NY).

Protein Extraction and Digestion from the Rat Brain and AD Brain {#sec2.2}
----------------------------------------------------------------

Human tissues of prefrontal cortical regions were provided by the Brain and Body Donation Program at Banner Sun Health Research Institute. The AD case with short post-mortem interval (\<3 h) was clinically and pathologically characterized in accordance with established criteria.^[@ref32]^ This study was approved by Banner


performed by the SEQUEST algorithm (version 28 revision 13)^[@ref41]^ against a composite target/decoy human or rat protein database.^[@ref42],[@ref43]^ The target human protein database was generated from Uniprot (combined Swissprot and Tremble) human database containing 71 809 protein entries. The target rat protein database contained 35 570 protein entries. Spectra were searched with ±10 ppm for precursor ion mass tolerance, ± 0.02 Da for fragment ion mass tolerance, fully tryptic restriction, dynamic mass shift for oxidized Met (+15.9949), two maximal missed cleavages, and three maximal modification sites. Only *a*, *b*, and *y* ions were considered during the search. The peptide spectrum matches (PSMs) were first filtered by the length of matched peptides (removal of PSMs with six or fewer amino acids) and then by mass accuracy. The survival PSMs were furtherwere eluted at 30% of ACN on this extra-long column, suggesting that higher organic gradient was required for efficient elution of mammalian cellular peptide complex on ultralong C18 LC columns.^[@ref5]^ This observation may be explained by the increasing interaction between peptides and C18 beads created by the long distance through which peptides have to travel.

![Optimization of the LC gradient buffer for peptide elution. ∼2 μg of peptides was loaded on the long column and eluted in a 10--45% gradient of acetonitrile over 4 h. The LC elution profile was represented by total ion current (solid black line) along with the gradient (dotted black line). The number of identified peptides every 2 min was plotted (solid red line). About 157 ± 42 peptides were identified in every two min.](pr-2014-00882h_0003){#fig3}

To


between grading system of lipomatosis and symptom development. Treatments relies on the severity of neurological deficits. Just weaning of steroids and weight loss or treatment of endocrinopathy can achieve good results. But our patient had neither obesity nor steroid treatment. Surgical intervention is indicated in case of severe or progressive neurologic deficits. Recovery can be either immediate or occur over several months, although reports indicate that the majority of patients experience improvements in neurological symptoms immediately after surgical intervention. Furthermore, patients with pathological conditions in the lumbar (cauda equina) region tend to make better recoveries following surgical decompression than patients with pathological conditions in the thoracic region[@B10].

CONCLUSION
==========

We report a rare case of idiopathic SEL causing cauda equina syndrome in a non-obese young patient. Although rare, idiopathic SEL shouldwith a correlation coefficient of up to 0.636 [@pone.0039195-Xu1]. Another classifier called seeSUMO has recently been developed for predicting sumoylation sites, which used the domain-specific knowledge in terms of relevant biological features for input vector encoding [@pone.0039195-Teng1]. However, the prediction performances achieved by these existing methods require improvement mainly because the database employed in their tool development is limited and does not represent the full characteristics of SUMO substrates. For example, there are cases in which non-sumoylated proteins have always been falsely predicted to be sumoylated simply because they contain the consensus motif ψKxE. In other cases, proteins that lack this consensus motif may actually be sumoylated and not identified. Therefore, there remains a significant need to develop better predictors of protein sumoylation sites.

The input feature vector (i.e.,


competitive sumoylation site predictor termed SUMOhydro was developed in the present study. We included amino acid hydrophobicity in a binary encoding scheme, and this hydrobinary encoding was proven suitable for the prediction of sumoylation sites, which gives SUMOhydro a better level of performance and favorable results relative to previously described predictors. Not only does its ability to clearly characterize amino acids in different positions surrounding a potential sumoylation site, it also pays attention on the biochemical property at different positions. It has been well known that more than two-thirds of the known sumoylation substrates have the consensus motif ψKxE, suggesting that sumoylation targets the substrate proteins at a specific position in most cases. Hence, we choose the position-specific binary encoding as one part of our hydrobinary encoding approach.which contains 332 non-redundant sumoylation sites in 197 proteins compiled from research articles published prior to October 18, 2007. The second source was the PubMed database, which was searched using the keywords "SUMO" and "sumoylation" to obtain data from October 18, 2007, to January 16, 2010. This search found 38 experimentally defined sumoylation sites in 27 proteins from 362 research articles. These primary sequences were also extracted from the UniProt database (<http://www.uniprot.org/>) (see Supporting Information, [Document S1](#pone.0039195.s001){ref-type="supplementary-material"}). In total, 221 proteins, covering 370 sumoylation sites, were compiled into the initial positive dataset. Similar to other PTM sites predictors, the input for a sumoylation site predictor is also generally represented by a 2n+1 residue-long sequence with a K in the central position (i.e., the window size is equal to


a threshold of 40% sequence identity to avoid an overestimation of the performance that would be caused by sequence redundancy. This procedure ensured that any given fragment pairs in all of the remaining positive and negative samples shared a sequence identity of less than 40%. Finally, we obtained a filtered sumoylation site dataset containing 358 positive (Positive_K) and 8071 negative samples (Negative_K), which were utilized to train and test SUMOhydro (see Supporting Information, [Documents S2](#pone.0039195.s002){ref-type="supplementary-material"} and [S3](#pone.0039195.s003){ref-type="supplementary-material"}).

To independently compare the prediction performance of SUMOhydro with previous predictors, we used a test dataset consisting of an additional 24 sumoylation sites (Positive_test.txt) and 510 non-sumoylation sites (Negative_test.txt) in 17 proteins that were reported from June 1, 2010 to January 1, 2012 (see Supporting Information, [Documents S4](#pone.0039195.s004){ref-type="supplementary-material"} and [S5](#pone.0039195.s005){ref-type="supplementary-material"}). This datasetsequence fragment, such as the prediction of RNA-binding sites [@pone.0039195-Cheng1], [@pone.0039195-Kumar1] and subcellular localizations of Gram-negative bacterial proteins [@pone.0039195-Wang1]. The input for each sequence fragment consisted of a corresponding row in the position-specific scoring matrix (PSSM) generated from three cycles of PSI-BLAST [@pone.0039195-Altschul1] searches against the Swiss-Prot non-redundant database using an E-value of 0.001.

### KNN encoding {#s4b4}

KNN encoding scheme is based on the concept of the nearest neighbor algorithm, which is a method for classifying a new object according to the *k* closest samples in the feature space [@pone.0039195-Gao1]. The detailed procedures of this encoding method are described as follows. For two sequence fragments S~1~ {aa~1~, aa~2~, ..., aa~n-1~, aa~n~} and S~2~ {aa~1~, aa~2~, ..., aa~n-1~, aa~n~}, their distance (S~1~, S~2~) can be defined as:.where n is the


the sumoylation sites (Positive_test.txt) that were used in the independent test dataset.

(TXT)

######

Click here for additional data file.

######

Document S5 contains the non-sumoylation sites (Negative_test.txt) that were used in the independent test dataset.

(TXT)

######

Click here for additional data file.

We thank Dr. Ziding Zhang (China Agricultural University) for his valuable discussions and kind assistance on this work. We are also grateful to Dr. Binghui Li (Tianjin Medical University Cancer Institute and Hospital, China) for his critical evaluation of this manuscript.

**Competing Interests:**The authors have declared that no competing interests exist.

**Funding:**This work was supported by the National Basic Research Program of China 2010CB529403, 2011CB933100, the Tianjin TSTC grant 09ZCZDSF04300, the National Nature Science Foundation of China NSFC30772528, NSFC81072158, and the National Program for Changjiang Scholars and Innovative Research Team in UniversityIRT1076, IRT0743. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

[^1]: Conceived and designed the experiments: YZC GY. Performed the experiments: YZC. Analyzed the data: YZC. Contributed reagents/materials/analysis tools: YZC ZC. Wrote the paper: YZC. Manuscript preparation: ZC. Method assessment: YAG.


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Offshore oil and gas-focused engineering and construction firm, McDermott International Inc. (MDR - Analyst Report) has won three consecutive contracts, the most recent one from Brunei Shell Petroleum Company Sdn. Bhd. (“BSP”).

Per the agreement, McDermott will transport and set up offshore structures at BSP’s Champion Waterflood B2/3 project. The company will install four jackets at water depths of 25–30 meters. McDermott expects to complete this project, which was incorporated in its fourth-quarter 2013 backlog, in the third quarter of this year.

This contract follows the Arabian Gulf deal wherein the company was awarded an engineering, procurement, construction and installation (EPCI) job by an operator in the Arabian Gulf. The project undertaken by the company involves engineering, fabrication, transportation and installation of four new offshore


Introduction

If you follow me on Twitter you will know that I'm a massive Jimmie Ward guy, to the point where he may be my favourite prospect in the entire draft. When I watch his tape, it just jumps off the screen at me. Whether he is making plays in centre field or blocking punts (which he is an expert at). Jimmie is a guy I want on the Jets and a player I would actively target going into the draft.

Jimmie Ward was a three year starter in 6A competition in Alabama, earning defensive MVP his senior season. His numbers were exceptional throughout and he performed on both defense and on special teams. So it was slightly confusing when he was rated as just a 2* prospect by manyFemale Candidates for State Offices Break a Record

By Allison Stevens

Washington Bureau Chief

Thursday, October 19, 2006

Women seeking state legislative offices are at record levels and plenty are also seeking executive state posts. Women's PACs are glad; as women fill up local political pipelines, these donors say more will be propelled into higher office.

Subhead:

Women seeking state legislative offices are at record levels and plenty are also seeking executive state posts. Women's PACs are glad; as women fill up local political pipelines, these donors say more will be propelled into higher office.

Byline:

Allison Stevens

WASHINGTON (WOMENSENEWS)--Female candidates are loading up the bottom of this year's election ballots and weighting the springboard to higher office more heavily in favor of women.

"I really think you're going to see women not only at the federal level


but at the state and local level win races this year," said Karen White, national political director at EMILY's List, a political action committee in Washington, D.C., that has worked to build a "pipeline" of pro-choice Democratic women poised to run for higher statewide and federal office.

Female candidates for state legislative offices are at record levels, reversing a dramatic downturn in the last election cycle. This year, 2,431 women are running for state House and Senate seats, a 10 percent jump from 2004, when 2,220 women sought those seats.

Female state lawmakers are critical to gaining gender parity in the higher echelons of politics, said Clare Giesen, executive director of the Washington-based National Women's Political Caucus. "It cannot be overemphasized: the necessity to have women represent us on aDNA sequence can be represented by DS = \<S~1~*S*~2~*S*~3~⋯S~*n*~\>, where n∈Z^+^, S~*n*~∈∝, S~*n*~ is called an item.

RNA sequence. There exists an alphabet set *τ* = {A,C,G,U}, the RNA sequence can be represented by RS = \<S~1~S~2~S~3~⋯S~*x*~\>, where x∈Z^+^, S~*x*~∈*τ*, S~*x*~ is called an item.

Protein sequence. There exists an alphabet set *ω* = {A,C,D,E,F,G,H,I,K,L,M,N,P,Q,R,S,T,V,W,Y} of 20 different letters, the DNA sequence can be represented by PS = \<S~1~S~2~S~3~⋯S~*m*~\>, where m∈Z^+^, S~*m*~∈*ω*, S~*m*~ is called an item.

Biological sequence. Given a sequence BS, if the type of BS, BS.type∈{DS,RS,PS}, then BS is called a biological sequence. The DS, RS and PS are denoted as types of the BS. For a type of BS as DS, it can be written as BS.type = \[DS\].

Parent sequence and child sequence. Given any two sequences


BSP.

Algorithm model {#sec005}
---------------

The proposed algorithm to mine the pattern in the biological sequences has four steps. (1) scan the sequence database once to construct the position table 1-ST and database index 1-DB-Index of single items; then the fast support counting algorithm is used to get frequent sequence 1-BSP. (2)in order to expand (k+1)-BSP from k-BSP(k = 1, k∈Z^+^), we propose a sequence connection strategy named as BS-Ext to obtain (k+1)-BSP by connecting k-BSP. (3)the index table ST and database index DB-Index will be updated to (k+1)-ST and (k+1)-DB-Index. (4) The (k+1)-BSP is obtained by the support counting algorithm. The recursive processes will be terminated until (k+1)-DB-Index is empty. These processes are shown in [Fig 1](#pone.0195601.g001){ref-type="fig"}. Definition 6. Sequence extension strategy BS-Ext. There are two k-BSP~*s*~ BSP~1~ and BSP~2~.MSPM algorithms. The execution time of FBSB algorithm is around 10 times that of Mpbsmi algorithm. The main reason is that the Mpbsmi algorithm only processes sequence database index but the FBSB algorithm scans the entire sequence database. Meanwhile the time consumption of MSPM algorithm is significantly higher than Mpbsmi and FBSB algorithm, which is because MSPM algorithm produces a large number of basic candidate pattern s, sorting and combining the pattern is time-consuming. Mpbsmi reduces a large number of candidate patterns by sequence extension strategy BS-Ext, which reduces time cost.

![Algorithm efficiency comparison.](pone.0195601.g002){#pone.0195601.g002}

Experiment 2. Algorithm scalability analysis on data size of the relationship between data size and time consumption.

The data used in the experiment is shown as [Table 5](#pone.0195601.t005){ref-type="table"}. Every experimental group contains one protein family and selects


has shown that FBSB algorithm has over performed MSPM algorithm in terms of efficiency.

\(3\) The algorithms based on the parallel computing technology.

Another co-existing biological sequence mining algorithm stream is to take advantage of parallel computing. Literatures \[[@pone.0195601.ref029]--[@pone.0195601.ref032]\] used the MapReduce and Spark framework based on distributed statistical approach and are suitable for cloud computing environment running on multiple computers.

The proposed algorithm in this paper has proved its merit to obtain continuous biological sequence patterns efficiently. By further improvement, it can be used to acquire all the biological sequence patterns. There is also a plan to adapt the algorithm in cloud computing environment.

Conclusion {#sec013}
==========

This paper proposes a new algorithm Mpbsmi based on data index technology for improving the efficiency of biological sequence pattern mining. Based on the index technique,Science Foundation of China under Grant No. 61572420, No. 61472341, No. 61772451 and No. 61772449 (JR), the Natural Science Foundation of Hebei Province China under Grant No. F2016203330 and No.F2015203326 (JR). The aut-hors are also appreciated to the valuable comments and suggestions of the rev-iewers.

[^1]: **Competing Interests:**The authors have declared that no competing interests exist.


            markerOptions = new MarkerOptions().position(marker_position).icon(BitmapDescriptorFactory.fromResource(R.drawable.placeholder_pin)).snippet(String.valueOf(x));
            marker = map.addMarker(markerOptions);

        }
    });
}

I'm doing this in a loop to add about 20 markers but I find that on first run of the code only 5 or 7 markers are added so I've switched to using the lib and an AsyncTask like this.
for(int x =0; x < mapIcon_url.length; x++){

    new AddMarker().execute(mapIcon_url[x]);
}

public class AddMarker extends AsyncTask<String, Integer, BitmapDescriptor> {

    BitmapDescriptor bitmapMarker1;
   Françoise’s apparent independence, she needs Pierre to approve her actions and give them direction. Françoise’s self-deception and the inauthenticity of her life anticipate de Beauvoir’s analysis of l’amoureuse, the woman in love, in The Second Sex. Confronted with a rival, Françoise becomes aware that her self-assurance and detachment are illusory. Her growth as a character occurs as she sheds the unexamined rational premises she holds about herself and her relationship with Pierre. The gap between the intellect and the emotions continues to widen until it reaches a crisis in the murder of Xavière. Françoise is finally forced to confront her long-concealed hatred. In spite of its often stylized dialogue, She Came to Stay is a lucid, finely executed study of love and jealousy and one of de Beauvoir’s


1441 8.2 % John Cody 1396 8 % Brice Johnston 1340 7.6 % Cao Boi Bui 1303 7.4 % Aaron Reisberger 1299 7.4 % Ace Gordon 1258 7.2 % Marcus Lehman 1223 7 % Spencer Duhm 1156 6.6 % Hunter Ellis 1090 6.2 % Darnell Hamilton 1059 6 % Max Dawson 947 5.4 % Drew Christy 913 5.2 % Peter Baggenstos 882 5 % Zane Knight 863 4.9 % Bobby Mason 795 4.5 % Cliff Robinson 576 3.3 %

How would this season pan out if it became a reality? Who would capitalize on their second opportunity and elevate themselves to Survivor glory? Let us know your thoughts in the comments below.

Thanks to everyone that took part.

Written bymode forearms

Devastator’s combined mode rifle

Devastator’s combined mode hands

Devastator’s combined mode chest armor

Devastator’s combined mode head

Long Haul’s front grill

Devastator’s combined mode vents on crotch and chest armor

In the end, I felt this custom was pretty fun. This is the first custom I did that wasn't a complete overhaul. I wish tht whomever wins it, enjoys it just as much~ :D


Android Oreo-based Samsung Experience 9. For example, the new full-screen Quick Settings menu shifts everything down so all the tiles are easier to reach one-handed.

As smartphones continue to get taller, it makes sense for Samsung to focus on improving one-handed usability. There’s still time for the design to be cleaned up as we’ve seen with the progression of the night theme in the leaked beta builds. We’ll continue to update you with any changes we find in the upcoming Samsung Experience 10 betas. Let us know what you think of all these changes in the comments.and the guideline applications stated in the

Presentence Report.        The district court imposed three concurrent

prison terms of 120 months, plus five years of supervised release.

      At Robinson's sentencing hearing, his counsel again objected

to   the   court's   consideration   of   his   prior   trips   to   Jamaica.

Counsel argued that the names of the two arrested individuals who

provided this information had not been revealed and that the

Presentence Report addendum did not state how the information may

have been corroborated.       The Government called on Agent Unger for

a response, although the record does not show that he was sworn as

a witness in


actually calling your generateSecretNumber() method, you'r declaring a variable instead. Remove the declaration in your main, and change the printing line to System.out.print("Random number is: " + generateSecretNumber());.
Next, the generateSecretNumber() method should not have any arguments, since it determines what it's going to do entirely by itself, and doesn't require any outside data. Since the arguments are gone, you also need to declare int w, x, y, z; at the beginning of it.
Secondly, you're generating a random integer without an upper bound. This is not at all what you'd want, instead, your upper bound for the rand.nextInt() calls should be 10, resulting in rand.nextInt(10). This will pick a random integer anywhere from 0 to 9.
And finally, you're returning the sum of the digits rather than the actual four-digitnumber that they'd make. Instead, return the sum of each of the digits times their place. For example, the fourth digit should be w * 1000.
Resulting code example:
public class RandUniqueFourDigits {
    public static void main(String[] args) {
        System.out.println("Random number is: " + generateSecretNumber());
    }

    public static int generateSecretNumber() {
        Random rand = new Random();
        int w = 0, x = 0, y = 0, z = 0;

        // Generate each digit until they're all unique
        while(w == x || w == y || w


      circleInsetBottom);

    layerDrawable.setLayerInset(2,
        (int) (circleInsetHorizontal - halfStrokeWidth),
        (int) (circleInsetTop - halfStrokeWidth),
        (int) (circleInsetHorizontal - halfStrokeWidth),
        (int) (circleInsetBottom - halfStrokeWidth));

    layerDrawable.setLayerInset(3,
        circleInsetHorizontal + iconOffset,
        circleInsetTop + iconOffset,
        circleInsetHorizontal + iconOffset,
        circleInsetBottom + iconOffset);

    setBackgroundCompat(layerDrawable);
  }

  Drawable getIconDrawable() {
    if (mIconDrawable != null) {
      return mIconDrawable;
    }else if (mIcon != 0) {
      return getResources().getDrawable(mIcon);
    } else {
      return new ColorDrawable(Color.TRANSPARENT);
    }
  }

  private StateListDrawable createFillDrawable(float strokeWidth) {
    StateListDrawable drawable = new StateListDrawable();
    drawable.addState(new int[] { -android.R.attr.state_enabled }, createCircleDrawable(mColorDisabled, strokeWidth));
    drawable.addState(new int[] { android.R.attr.state_pressed }, createCircleDrawable(mColorPressed, strokeWidth));
    drawable.addState(new int[] { }, createCircleDrawable(mColorNormal, strokeWidth));
    return drawable;
  }

  private Drawable createCircleDrawable(int color, float strokeWidth) {
    int alpha = Color.alpha(color);
    int opaqueColor = opaque(color);

    ShapeDrawable fillDrawable = new ShapeDrawable(new OvalShape());

    final Paint paint = fillDrawable.getPaint();
    paint.setAntiAlias(true);


gains over its prior season premiere. Rick and Morty season three is currently in production.

Highlights in the new Funko Rick and Morty collection include the following:

Rick and Morty Pocket Pop! Keychains

Rick, Morty and Mr. Meeseeks are now available on-the-go thanks to new keychains

from Funko. Each highly detailed keychain captures the expression of

the character and are a must-have for Rick and Morty fans.

Coming in April!

Rick and Morty Mystery Minis

The Rick and Morty Mystery Minis blind bag collection includes all of your

favorite characters from the popular series on Adult Swim. Collect all 12 of the highly

stylized characters for the ultimate mini Rick and Morty collection.

Coming in April!

Rick and Morty 5” Action Figures

Funko is bringing the world of Rick and Morty to life with the

introduction of 5” fully-posable Action Figures.

Each figureslow mass storage device to operating memory. Also, a physical operating memory that has gaps of unused physical address space (i.e., a fragmented memory) can be made to appear as a contiguous address space in the virtual realm.
One important application of virtual addressing is the storage and retrieval of graphics objects, such as textures, depth information and color information, in operating memory. Because graphics objects are often used to provide real-time visual effects, it is important that graphics objects be retrieved from memory quickly and without spending excessive time translating their virtual address references.
In many computer systems, virtual addresses are translated into physical addresses by a processor (or other bus master) before the processor issues memory access requests to a memory controller. In other computer systems, at least


and head," so that she was bound to turn to starboard to make a port to port passage with them. See Art. 18, 33 U.S.C.A. § 203. How far she would have had to turn out to pass these tugs and how close that would have brought her to the Choctaw was not developed in the evidence nor discussed in the opinion. That it was impossible for her to maintain the course she was on when sighted by the Choctaw and that her navigation would have been made more difficult by the position of the Choctaw had she tried to pass between the latter and the tugs seems self-evident. Whether it would have been possible for her so to navigate had she observed the Choctaw in time hasWhether the Choctaw would have been at fault in not sounding a passing signal to the Greene, if there had been no other vessels in the vicinity, we need not determine. The Choctaw knew of the presence of the Sarah, which she had recently overtaken and passed, and probably knew of the presence of the tug, which was almost abreast; she is chargeable with knowledge that the Greene was obligated to pass them to port *621 and would have to change her course to do so; whether the Greene would attempt to pass between the Choctaw and the tugs or would shape her course so as to leave all three of the on-coming vessels on her port side, the Choctaw could only surmise. Since she was uncertain of


Dennis Gibson, Keith Altomare and Tim Crenshaw had their heads shaved live on the air Monday morning Feb.12. The three staff members gave up all of their locks to draw attention to the plight of those suffering from cancer, taking chemo treatments and losing their hair. Prior to taking it all off a pledge drive was run on KBCH asking listeners to make pledges to Snow flake Society, helps North Lincoln County women pay for mammograms, or the Cancer Society. The three staff members were joined by 9 other community leaders raising more than $800.00. Photo: Newport News Times<?xml version='1.0' encoding='utf-8'?>
<section xmlns="https://code.dccouncil.us/schemas/dc-library" xmlns:codified="https://code.dccouncil.us/schemas/codified" xmlns:codify="https://code.dccouncil.us/schemas/codify" xmlns:xi="http://www.w3.org/2001/XInclude" containing-doc="D.C. Code">
  <num>42-520</num>
  <heading>Estates by sufferance.</heading>
  <text>All estates which by construction of the courts were estates from year to year at common law, as where a tenant goes into possession and pays rent without an agreement for a term, or where a tenant for years, after the expiration of his term, continues in possession and pays rent and the like, and all verbal hirings by the month or at any specified rate per month, shall be deemed estates by sufferance.</text>
  <annotations>
    <annotation type="History" doc="Stat. 56-2-ch854" path="§1034">Mar. 3, 1901, 31 Stat. 1352, ch. 854, § 1034</annotation>
    <annotation type="History">June 30, 1902, 32 Stat. 538, ch. 1329</annotation>
    <annotation type="Prior Codifications">1973 Ed.,


divided by 1006.
614
What is the remainder when 90203090 is divided by 208?
146
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9
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31
Calculate the remainder when 4999943 is divided by 45.
38
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159
Calculate the remainder when 12247036 is divided by 1489.
11
What is the remainder when 39180513 is divided by 10929?
48
Calculate the remainder when 1007398 is divided by 2027.
2006
What is the remainder when 2460720 is divided by 410119?
6
What is the remainder when 7776213 is divided by 4851?
60
Calculate the remainder when 2873945 is divided by 167.
42
What is the remainder when 2796714 is divided by 2710?
2704
Calculate the remainder when 18167092 is divided by 64422.
88
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34
Calculate the remainder when 20138 islegs electric two sides ep tour

It’s Saturday night, around 11pm and Perth rockers Legs Electric are about to take us on a “bohemian rock journey” Ama Quinsee the frontwoman declares as the ladies enter the stage composed with confidence, attitude and style. This is the 5th show of their “Two Sides” regional tour around Aus, showcasing their new EP.clink link below to view full review


   File.WriteAllText(@"D:\path.txt", json);
                Console.WriteLine(json);

            }

I'm lost, if someone can help me. Already give a search on Google, but the answer didn't come up in my head, already trying for a few time, slowly I'm getting but now is time to ask for help lol
For the list I was talking about, I'll explain it. I have a sqlite DB that have various information from mangas etc... I execute a query where I filter by a id, "SELECT * FROM MangaChapter WHERE manga_id = 'someid'", then i put the result on a list using a for loop. In the DB chapter urlQ:

Angular and JSON interaction?

I'm trying to implement a very basic system involving angular.js and JSON, but I can't get it to behave.  All I want to do is get the value for a particular field in my JSON file and spit it onto the page.  Can anyone see why this isn't working?  It finds the database every time, but I can't seem to access the object.
HTML & JS
<html lang="en" ng-app="ngApp">
<script src="https://ajax.googleapis.com/ajax/libs/angularjs/1.3.16/angular.min.js"></script>
<script>
    var ngApp = angular.module('ngApp', []);
    ngApp.controller('ngCtrl', function($scope, $http){
        $http.get("db.json").success(function(data){
            console.log("Database found");
            $scope.data = data;


hand, so we don't include stdio(3). */
	t = tmp;
	do {
		*t++ = "0123456789"[errnum % 10];
	} while (errnum /= 10);

	strcpy (buf, UPREFIX);
	for (p = buf + sizeof(UPREFIX) -1;;) {
		*p++ = *--t;
		if (t <= tmp)
			break;
	}

	return buf;
}

char *
strerror(int num)
{
	static char buf[40];			/* 64-bit number + slop */
	return __strerror(num, buf);
}

#endif
---
abstract: 'We associate tape casting and magnetron sputtering techniques to engineer flexible nanostructures using ZrO$_2$ green tape as substrate. We systematically investigate the structural, magnetic and electrical properties of NiFe/Cr/NiFe trilayer nanostructures, with variable thickness values of the NiFe and Cr layers, grown onto rigid glass and flexible ZrO$_2$ tape substrates. We verify the mirroring of these properties in the trilayer nanostructures, irrespective on the kind of employed substrate. The fact that the trilayer nanostructures can be reproduced in distinct substrates corresponds to an important advance for their applicability. The results place the ZnO$_2$ green tape as an attractive candidate for application as low-cost flexible substrate in the development of electrical and magnetic sensor elements with high sensitivity to mechanic stress.'
address:
- 'Departamento de Física, Universidade Federal do Rio


characterized by a magnetization reversal at fields close to the coercive field, occurring mainly through domain wall motion, followed by a linear approach to the magnetic saturation in which the main magnetization mechanism is the magnetization rotation. The drastic change of the shape of the magnetization curves reveals the deterioration of the soft magnetic properties and the appearance of an out-of-plane anisotropy contribution [@PRB69p174402; @JAP103p07e732; @PB404p2784; @JAP114p053908], features directly related to the increase of the saturation and coercive fields as the NiFe thickness is raised. Despite the strong changes in the magnetic behavior with the NiFe thickness, notice the striking similarity between the curves obtained for trilayer nanostructures with distinct substrates, um fact clearly evidenced in the direct comparison of magnetization curves (Fig. \[fig03\](d)), as well as in the behaviorthree-story bookstore that was a temple of clean efficiency until 2009. Quietly smart, not musty but modern, it always seemed to good to be true. Now the space holds a CVS.

In between Newbegin’s faint echo and Stacey’s clean aura there’s the corner that held Cafe Capriccio in the early ’90s, urbane and snug. Also, the most recent loss, Jeffrey’s Toys at the base of the Monadnock Building on Annie Alley. A great destination for my daughter to explore on her visits downtown — and felled in 2015 for a still-empty space where the windows proclaim “Flagship Restaurant Opportunity.”

This is small change compared to the razing of the Fox Theater in 1963 (before my time, still a sore point for older locals), or how the Old Main became the


NULL);

    RtlFreeUnicodeString(&us);

    if(!NT_SUCCESS(status))
    {
        DbgPrint("Failed ZwCreateFile! 0x%x \n", status);
    }

    InitializeObjectAttributes(&oa,NULL,OBJ_CASE_INSENSITIVE|OBJ_KERNEL_HANDLE,NULL,NULL);

    status=ZwCreateSection(
        &hSection,
        SECTION_MAP_READ,
        &oa,
        NULL,
        PAGE_READONLY,
        SEC_IMAGE,
        hNtoskrnl
        );
    if(!NT_SUCCESS(status))
    {
        DbgPrint(("Failed ZwCreateSection! 0x%x \n", status));
       combat situations, making it a worthwhile entry in the genre.

Now for the good stuff. If you’re a veteran to the series, you know that you don’t play Nep for the gameplay alone.

The Hyperdimension Neptunia series is well-known for its formula of mixing its JRPG gameplay with the storytelling of a visual novel, and Hyperdevotion Noire is no different. Unlike the main series though, this game is set in an alternate universe, which means that there will be quite a few inherent differences and deviations this time around. As the title suggests, Noire is the protagonist instead of Neptune and the CPU candidates either are never seen or don’t even exist. Those are pretty big changes from the main universe, but perhaps the largest is the addition of a


true self-insert character: an awkward, faceless young man who finds himself saving Noire and becoming her secretary. Now, in addition to the normal comedic storytelling of the series, players will be able to be praised for their hard work by every CPU except for Noire, who offers up heaping helpings of tsundere on the reg.

Those are pretty big changes from the main universe, but perhaps the largest is the addition of a true self-insert character: an awkward, faceless young man who finds himself saving Noire and becoming her secretary. Now, in addition to the normal comedic storytelling of the series, players will be able to be praised for their hard work by every CPU except for Noire, who offers up heaping helpings of tsundere on the reg.

They eventhe digital signal into an analog signal, thereby a speaker outputs the voice. In the A/D and D/A conversion technique related to voice, converting a signal component of an audible band without the change thereof and securely removing a signal component out of the audible band are required.
The handling of a frequency component is realized by the digital filter. The more filter is close to an ideal filter (the gradient of the frequency characteristics in the transition band is infinity), the more increased the order of the structure is and the scale of the circuit becomes increased. Accordingly, it is common that the filter is divided into a plurality of stages so that the out-of-band noise component is slowly removed to extract the needed band of frequency component.
FIG.


decreased from 128Fs to 4Fs, but the ratio thereof is optional. For example, the down-sampling can be performed till Fs, and, in this case, the sharp SINC filter corresponding thereto may affect the signal band such as attenuating a portion of the needed signal. In order to the compensate it, the frequency characteristics of the low pass filter 5 should finely adjusted. In this case, in order to realize the fine frequency characteristics of the low pass filter 5, a plurality of a design parameters are required and, accordingly, the circuit scale may be increased.
On the contrary, the case that the output of the SINC filter 3 is not decreased to 4Fs can be considered. In this case, since the structure of the SINC filter 3 is simply,and bladder outcomes 1 year after ischemia. The model relies on three predictors: strength of the legs, the presence of sensation in the S3 dermatome, and the part of the SCIM assessing breathing and bladder and bowel control. A simplified model relying on leg strength only was also tested. Bladder outcomes were evaluated according to the score of item six of SCIM. In total 85 patients (56 males (66%), mean age 55 years) were included. Twenty-three patients (27%) showed complete bladder function recovery one year after ischemia. Both models showed a very good predictive power: the area under the receiver operating characteristics curve (aROC) of the two models was 0.825 and 0.822, respectively. Comparable to acute traumatic SCI, also in ischemic SCI the outcome of full bladder function


as compared with daytime rest period and duration of such increase for at least 2.5 h. The stress-index has been shown to be a reliable parameter of the beginning of the nocturnal phase of cardioactivity, while preservation of the typical circadian rhythm can be considered as a bioindicator in the biomonitoring systems of the quality of superficial waters.will have to wait until later this year to discover what will be produced.

Marcus Arthur, MD of BBC Worldwide UK said, “Both Doctor Who and LEGO enjoy a particularly close relationship with their fans and I can’t wait to see what LEGO produce.”

Emma Owen, UK spokesperson for LEGO Ideas commented: “We’re extremely excited to announce that a Doctor Who and a WALL-E set will be released as our next LEGO Ideas fan based sets, congratulations to the designers Andrew Clark and Angus MacLane!

“After receiving over 10,000 votes from the online community and having gone through rigorous toy testing from our expert panel, these awesome sets are on track to be on shelves later this year. The final set designs, pricing and availability are being worked out as we


in and crash down on top of electrode.

Cool battle, bro! Here’s yo’ new Thunder Badge.

As I climb out the rubble that once was the gym I look around to see people running around and emergency services in action in the streets. I turn to Tremors who followed me.

- That was a close one Tremors…

Iwarrrk…

- Things might get tougher from here onwards.

Iwaaarrk.

- Do you want to try this Metal Coat? It might provide you with some protection.

Iwark!

Tremors nods. It turns out that the metal coat is a spray that solidifies soon after contact, I apply it to Tremor’s body and give a double coating to his scar.Light level of the drops you get is dictated by the quality of the gear you have, up to a cap that defines the maximum quality of gear a certain activity can provide.

That means that if you are Light level 350, and you’re doing an activity that can drop gear up to 365, the drops you will get will be between 351 and 354. If you do the same activity again when you’ve upgraded your gear to 354, you’ll probably get items with up to around 357 or 358 Light. You will continue to get incremental upgrades from repeating that activity until you hit 365 Light, which is the cap for that exercise.

After that, you’ll continue to get gear at 365 Light, but you’ll need to find an


just do the heroic strikes at 340 Light if you’re a very talented player with a good fireteam, but your damage will be reduced by about 30 percent. If you and some friends are up to the challenge, you may want to try it. Finding a random fireteam would likely end in disaster, however.

Aside from that, the way you’re probably going to get to 350 is by decrypting Legendary/purple-quality engrams and Exotic/yellow-quality engrams. Exotic engrams have a chance to drop from bosses and major enemies when you use the Three of Coins consumables you can buy from Xur with the Strange Coin currency.

Legendary engrams can drop from any enemy, but are a lot rarer than blue engrams. They also have a fairly high chance — maybe one inThe100.io.

It wouldn’t be Destiny without cheese

Destiny players are notorious for finding shortcuts around the game’s mechanics, and the community has figured out a way that can yield more heroic strike blue drops than farming strikes the regular way. But your fireteam has to coordinate well enough to execute it.

Heroic strikes come with random combat modifiers that change every week. One kind of modifier is an elemental “burn,” which amplifies all damage of a certain element, coming from both players and enemies.

This is a lot of fun, because it makes weapons deal crazy amounts of damage, but it can also allow enemies to kill you nearly instantly. More importantly, the enhanced damage from elemental burns can make it possible to kill enemies who aren’t normally supposed to die.

Omnigul, the


three pseudo scalar fields $u,v$ and $s$ ($s^T=(s^1\,\,s^2)$) accordingly the relations \[04\] &&V\_1=e\^[2]{}(u+AA\^Tv+As),\
&&V\_2=e\^[2]{}Gv-AA\^T V\_1+AV\_3,\
&&V\_3=e\^[2]{}(s+A\^Tv)+A\^TV\_1. The resulting effective three-dimensional theory can be expressed in terms of the three $2\times
2$ matrices $\G$, $\B$ and $\A$ of the following form [@HKMEP]: \[s3\] = ( -e\^[-2]{}+Gv\^2&GvGv&G ), = ( 0&-(u+As)\^Tu+As&0 ), =( s\^T+vA A ). The corresponding three-action reads: \[s4\] S\_3=d\^3x h\^( -R\_3+L\_3), where \[s5\] L\_3=[Tr]{}and $\J_{\G}=\nabla\G\,\G^{-1}, \,\, \J_{\B}=\nabla\B\,\G^{-1}$. To clarify the symmetric properties of the theory it is useful to introduce the following $6\times 6$ real matrix $\M$: \[s6\] = ( \^[-1]{}&\^[-1]{}(+)&\^[-1]{}(-+)\^[-1]{}&(-+)\^[-1]{}(++)&(-+)\^[-1]{}\^T\^[-1]{}&\^T\^[-1]{}(++)&1+\^T\^[-1]{}), where $\T=\frac{1}{2}\A\A^T$. This matrix satisfies the coset relations \[s7\] \^T=, Ł=, where \[s8\] Ł= ( 0&1&01&0&00&0&-1 ). The restrictions (\[s7\]) are preserved by the transformation \[s9\] \^T, where \[s10\] \^TŁ=Ł. The Lagrangian $L_3$, being expressed in terms of $\M$,invariant in respect to the transformation $M\rightarrow  C^+M C$, where $ C^+ L
 C= L$, so we deal with the symmetric space model with the unitary hidden symmetry. Our statement is the following: this new unitary $\sigma$-model coincides with the orthogonal one introduced in the previous section. This means that the matrix $M$ can be parameterized by the quantities $G,A,\phi,u,v,$ and $s$ in such a way that this parameterization will give the general solution of the coset restrictions (\[e2\]) and also it will guarantee the equality $L_c=L_3$. The rest part of this section is related to determination of the explicit form of this new unitary representation of the theory.

First of all, let us solve the unitary coset restrictions (\[e2\]); the result reads: \[e3\] M= ( P\^[-1]{}&i P\^[-1]{}Q-iQ


we consider the Josephson current switching $I(V)$ and differential conductance spectroscopy of the Andreev levels $dI_N(V)/dV$ as we vary the voltage $V$ along the normal terminal in a three-terminal SIS junction. The details of the Josephson current switching and spectroscopy of the Andreev states in a three-terminal SIS junction differ considerably from the ballistic SNS junction [@chang]. In a short SIS junction, having $(L \ll
\xi_0)$, the presence of an insulator forces the Andreev energy levels to the edge of the superconducting energy gap. The Josephson current in a short SIS junction therefore switches to zero when the voltage on the normal terminal is approximately equal to the energy gap, i.e. $eV
\simeq \Delta$, as we discuss in section 3. Section 4 shows that the terminal I-V characteristics of SIS Josephsonwhen $\phi = 0,
2
\pi$. Therefore, the energy levels at $\phi = 0, 2 \pi$ are unaffected by the presence of a tunnel barrier. When the phase difference is not $\phi = 0, 2 \pi$ this geometrical symmetry is broken, so the degenerate energy levels do split at any phase value other than $\phi
= 0, 2 \pi$. This failure of the energy levels to split at $\phi = 0,
2 \pi$ in s-wave SIS junctions is exactly the same geometrical symmetry leading to the ‘midgap’ energy levels in Josephson junctions formed from d-wave superconductors [@hu; @riedel-dnd].

To obtain a formula for the Andreev levels in Fig. \[fig:longsym\](a), we set $a = L/2$ in Eqs. (7)-(8) of Ref. [@bagwell]. The ‘effective phase’ $\alpha$ in the symmetric SIS junction then simplifies to $$\begin{aligned}
\sin(\alpha) \simeq \alpha \simeq 2\sqrt{T}|\sin(\frac{\phi}{2})|,
\label{phase_bagwell}\end{aligned}$$


          e^{\displaystyle i (\tilde{k}_e - \tilde{k}_h)a} & 0 \cr
                0 & (1 - \epsilon)  e^{\displaystyle i \phi}
                e^{\displaystyle -i (\tilde{k}_e - \tilde{k}_h)(a-L)} \cr
        }
\right) \;X \hspace{1.7in}  \nonumber \\
\left\{
\left( \frac{v_0}{u_0} \right)
\left(
        \matrix{
                t^*(\tilde{k}_h) & r^*(\tilde{k}_h) \cr
                r^*(\tilde{k}_h) & t^*(\tilde{k}_h) \cr
  i \tilde{k}_e L}
}
{\displaystyle
        F(\phi, \epsilon, T)
} \; ,
\label{transC}\end{aligned}$$ and $$\begin{aligned}
D_{1 \rightarrow 2}^{e} =
\left(\frac{v_0}{u_0} \right)
\left( 1- \left( \frac{v_0}{u_0} \right)^2 \right) \hspace{3.2in}
\nonumber\\
\frac{\displaystyle
        \left( t r^*(1 - \epsilon) e^{ \displaystyle -i \phi }
        e^{ \displaystyle i (\tilde{k}_e - \tilde{k}_h)(L-a) }
        + r t^*
        e^{ \displaystyle i (\tilde{k}_e - \tilde{k}_h)a }
        \right)
        \sqrt{1-\epsilon}
        e^{-\displaystyle i \tilde{k}_h (L-a)}
        e^{ \displaystyle i \tilde{k}_e


Monthly Cash BINGO at Saint John the Evangelist Catholic School, 116 East Bishop Street Bellefonte, PA 16823. Tuesday April 18th; Doors will open to the public at 6pm, First BINGO at 7pm. Games of Chance, Food and Drinks available. $20 for 20 games; Walk-Ins Welcome. For more information visit: facebook.com/events/247355495736414

Want to grow a lot of organic food in a small space?
Bellefonte Garden Club hosts Gene Bazan and Tania Slawecki as they share how they use several intensive techniques for growing food using images from their garden. Their methods increase yields, decrease purchased inputs and build soil fertility at low cost. Then on May 16 we will tour their garden to see the principles in action and ask questions.
April 18, 6:30 p.m., First Presbyterian Church, 203 N. Spring St.,election and promised the Senate he’d stay out of follow-up matters related to the Hillary investigation. Yet Sessions finds himself under criticism now for being involved in the review and firing of Comey, given that the review focused on the e-mail investigation and came while Comey was managing the Russia probe. Sessions was apparently enlisted to this task on the direct orders of President Trump, who has since admitted that the review was window dressing for Trump’s main reason for firing Comey, his frustration with Comey’s handling of the Russia probe. Which is how we ended up with another special prosecutor, former FBI director Robert Mueller.

A Better Way

It doesn’t have to be this way; it doesn’t have to be any of these ways. A new, separate inspector general,


rings of different pyDAT ligands form almost a straight line, with a N~2~--Co--N~2~^i^ angle of 167.4(2)°. In contrast, the other coordinated pair of N atoms of the pyridine rings is not linear, with a N~1~--Co--N~1~^i^ angle of 109.0(2)°. The pyridine and DAT rings in both ligands are tilted around the C--C bond by 12.6°. The average plane of bound ligands forms an angle of 57.9°. As expected, the DAT groups in metallotecton **6** are placed in trans-orientation. In the structure, each DAT group is linked by two N--H···N hydrogen bonds of type **IV** ([Scheme [3](#sch3){ref-type="scheme"}](#sch3){ref-type="scheme"}, distance N--H···N = 3.104(5) Å), giving rise to a three-dimensional network ([Figure [1](#fig1){ref-type="fig"}](#fig1){ref-type="fig"}b). Additional N--H···O hydrogen bonds involving nitrates and free NH~2~ groups reinforced the supramolecular network. Details of the hydrogen bonds andC~16~H~16~CuN~14~O~6~: C, 34.08; H, 2.86; N, 34.77. Found: C, 34.34; H, 2.85; N 34.77.

### Compound 9 {#sec4.1.4}

The reaction of **2** (0.05 g, 0.2656 mmol) with Zn(NO~3~)~2~·6H~2~O (0.039 g, 0.1328 mmol) according to the general procedure yielded 99% colorless crystals **9** with the composition of Zn(**2**)~2~·(NO~3~)~2~. FTIR (ATR): 3443.23, 3371.81, 3312.99, 3211.12, 3171.54, 3113.98, 1672.16, 1644.16, 1610.99, 1587.80, 1558.28, 1516.19, 1489.62, 1470.80, 1446.24, 1428.34, 1395.70, 1292.37, 1265.96, 1194.79, 1144.84, 1095.17, 1064.21, 1021.02, 993.41, 911.39, 824.24, 787.76, 748.94, 681.16 cm^--1^. HRMS (ESI) calcd for \[C~16~H~16~N~12~ZnNO~3~\]^+^*m*/*z* 502.0785, found 502.0796. Anal. calcd for C~16~H~16~N~14~O~6~Zn: C, 33.97; H, 2.85; N, 34.66. Found: C, 33.93; H, 2.87; N, 34.39.

Instrumentation {#sec4.2}
---------------

Crystallographic data were collected using a Bruker Venture Metaljet diffractometer with Ga Kα radiation and a Bruker APEX2 diffractometer equipped with a Cu Kα radiation


The operators of a drone involved in injuring an athlete in a West Australian triathlon have been referred to the Commonwealth Director of Public Prosecutions by the Civil Aviation Safety Authority.

The referral means the operators could be prosecuted if the Commonwealth Director of Public Prosecutions decides that there is reasonable evidence to make a case in court.

Raija Ogden is taken away on a stretcher. Credit:Everything Geraldton

In early April, Raija Ogden was running in Geraldton's Endure Batavia Triathlon, about 420 kilometres north of Perth, when she said she was hit on the head by a drone filming participants when it crashed. Paramedics were called and a witness said a “river of blood” ran down her face.

"I have lacerations on my head from the drone and the ambulance crew tookfor Rakudo progress, here’s some of the things that have been going on.

The bounded serialization branch has landed (and thus will be in the next release)! This has, as hoped, greatly decreased Rakudo’s startup time – an improvement that has been welcomed by a bunch of folks on #perl6. Module and setting pre-compilation is now also faster, along with loading of pre-compiled modules. Win all around.

Thanks to the serialization, various things have been unblocked. Amongst them, the constant declarator now takes non-literals on its RHS, and the BEGIN and CHECK phasers now work in r-value context. In both cases, the values are serialized if these things are done in a pre-compiled module.

masak++ merged his initial work on macros. While there’s much more to do in this area yet,


CoDDA: A Flexible Copula-based Distribution Driven Analysis Framework for Large-Scale Multivariate Data.
CoDDA (Copula-based Distribution Driven Analysis) is a flexible framework for large-scale multivariate datasets. A common strategy to deal with large-scale scientific simulation data is to partition the simulation domain and create statistical data summaries. Instead of storing the high-resolution raw data from the simulation, storing the compact statistical data summaries results in reduced storage overhead and alleviated I/O bottleneck. Such summaries, often represented in the form of statistical probability distributions, can serve various post-hoc analysis and visualization tasks. However, for multivariate simulation data using standard multivariate distributions for creating data summaries is not feasible. They are either storage inefficient or are computationally expensive to be estimated in simulation time (in situ) for large number of variables. Incharging cable long enough to reach the power outlet in your vehicle, as well as a dashboard or window mount. This setup works the same as it did when we showed you how to create time lapse driving videos using your iPhone.

The cable shouldn’t be difficult to come by, since most people have one or two spare ones lying around. The mount is easily bought from any electronics store or Amazon, which carries an abundance for around $20-$25.

In our time lapse article, however, we made no bones about using your current smartphone to do this. When performing the dash cam arrangement, it is best if you have a device that you won’t need to take off the mount or otherwise use to call, text, or play music. (Though


turn on the shock sensor, which will measure the impact of a collision, and change the unit settings from kilometers per hour to miles.

Another unique feature is emergency auto dial, which will dial an emergency contact number (for example: 911).

Checking out the recording settings, you can adjust the recording time and maximum storage allotment, which is 10GB by default.

Another important setting you might want to consider is video quality. The lower the quality, the more recordings you can fit into your storage allotment.

We could go on and on about the settings, as there are quite a few but if you decide to use AutoBoy Dash Cam, feel free to peruse them yourself.

For iPhone: DashCam

If you’re using an old iPhone, then the choice is simple: DashCam. DashCam includes allIran leader Ahmadinejad wants to attend Olympics

Written By THA on Thursday, 17 May 2012 | 23:00

Iranian President Ahmadinejad claims ‘enemies do not want Iranian athletes to win medals’ in the London Olympics. AP photo

Iranian President Mahmoud Ahmadinejad said yesterday he hopes to attend this summer’s Olympic Games in London but that the British authorities were reluctant to allow him, state media reported.

“I would like to be beside the Iranian athletes at the Olympic Games in London to support them, but (the British) have issues with my presence,” Ahmadinejad said, without offering further explanation.

“The enemies do not want our athletes to win medals, but our young people shall be present at the Olympic Games and, like Arash, give new reasons to take pride in Islamic Iran,” he said, quoted


 (d) s
d
Let h be (-1 + (-5)/(-6))*(-6)/(-2). Which is the nearest to 5?  (a) 5  (b) h  (c) 4
a
Let h(w) = -w**2 + 9*w + 3. Let s be h(9). Let m be (0 + 1/(-4))*-1. Which is the nearest to 0.1?  (a) s  (b) m  (c) 2
b
Suppose 13*t = 4*t - 27. Which is the closest to 5/2?  (a) 2  (b) t  (c) 2/3
a
Let r(x) = -x**3 - 4*x**2 - 5*x - 1. Let y be r(-2). Let l be 3/((-1)/(-2)*-41 + y). Which is the nearest to -2/9?  (a) l  (b) -0.1  (c) -4
a
Let h(l) = -5*l**3 - l**2. Let o be h(-1). Let f = 1 - 0.9. What is the nearestand elixir shops are set.

And in all honesty, after taking part in the game every. single. day. for five+ months, I spent $10 on gems to get a 4th builder. Since, you understand, I’ve probably invested more time in that sport that I’ve another previously 5 years due to the truth that I can decide it up and play when I have a few minutes. So, after spending every day for half a yr playing it, certain that is value $10 to me. that worth for money proposition is probably one of the best in any form of leisure I’ve consumed in a very long time.

You too can use hack on-line, in case you don’t want to add a cumbersome device in your Smartphone or Tab. The net


has also dropped significantly, down from a fourth-place ranking from pre-season, while Wingard jumped into the top 20 from rank 31.

Justin Westhoff - 21st in pre-season - has disappeared from Rucci's post-season audit.

STATE OF THE LISTS: Changes to Freo, Hawks, Eagles

Rucci's Top 50

1. Nat Fyfe (Fremantle)

2. Patrick Dangerfield (Adelaide Crows)

3. Josh Kennedy (Sydney)

4. Todd Goldstein (North Melbourne)

5. Josh Kennedy (West Coast)

6. Scott Pendlebury (Collingwood)

7. Luke Hodge (Hawthorn)

8. Dan Hannebery (Sydney)

9. Matt Priddis (West Coast)

10. Sam Mitchell (Hawthorn)

11. Dustin Martin (Richmond)

12. Andrew Gaff (West Coast)

13. Alex Rance (Richmond)

14. Taylor Walker (Adelaide Crows)

16. Brett Deledio (Richmond)

16. Jarryd Roughead (Hawthorn)

17. Robbie Gray (Port Adelaide)

18. Callan Ward (GWS)

19. Chad Wingard (Port Adelaide)

20. Dane Swan (Collingwood)

21. Eddie Betts (Adelaide Crows)

22. Shaun Burgoyne (Hawthorn)

23. Aaron Sandilands (Fremantle)

24. Travis Boak (Port Adelaide)

25. Cyril Rioli (Hawthorn)

26.the fastball in, so go ahead and offer at it.' He's a veteran, and he has multiple years in the game, so I think it carries a little more weight."

Each year, stories emerge about players taking the initiative to improve their performance. Colorado reliever Adam Ottavino benefited from a visit to the Driveline Baseball facility in suburban Seattle and some work on his mechanics and his pitch mix. Former first-rounder Colin Moran revived a flagging career with some swing changes in Pittsburgh after it became clear his approach wasn't cutting it in Houston.

Cleveland pitcher Trevor Bauer was once considered a rogue voice when he arrived in professional ball from UCLA and shared his innovative approach to training and analytics. Now that he's relatively in the mainstream, Bauer expects


more organizations to hire uniformed personnel as conduits, and for coaches to become more proficient in speaking the same language as front offices.

"Now more than ever, you have information about how to improve a player and what he needs to do, but there's a divide because you need to find people who are good at actually coaching and teaching it," Bauer said. "You need people who've played enough to be able to communicate with players and also be able to understand it intellectually and communicate with the front office. It's a rare combination.

"A lot of players don't want to hear about spin rate. But if the coach knows a pitcher's spin rate is down, and he knows how to coach spin rate, he can say, 'Hey, why don'tmessage and trains prospects to think critically on their way to Citizens Bank Park.

"Every year, some of the newer methodology resonates a little bit better with players, and certainly with young guys who are growing up on it," Fuld said. "They probably knew what WAR was when they were 12 or 13 or 14, where it would have been meaningless to someone my age."

When given a pop quiz, Hoskins does an admirable job of explaining wOBA -- a metric that measures a hitter's offensive contribution by assigning values to home runs, triples and so forth. But he picks and chooses the information he incorporates into his daily repertoire. Hoskins doesn't spend much time online checking his BABIP or monitoring his exit-velocity ranking, for one simple reason:


it's no wonder he didn't win more. 44% of his games were against ranked teams. 23% were against teams that finished in the Top Ten. That's an average of almost 3 top ten opponents a season! A good part of this is because his tenure overlapped with FSU's glory years, and the rest probably due to the SEC being strong (as well as Florida making a lot of SEC title games and good bowl games). In this respect, he's very similar to Lou Holtz: excellent numbers but very daunting schedules.

On the other end of the spectrum, we have our good friends in the Big Twelve, Bob Stoops and Mack Brown. Stoops has played the smallest percentage of Top Ten teams; Brown barely plays more than 1 team rankedOct. 26.

"The university is discriminating against individuals with mobility impairments ... because the stadium does not include a sufficient number of accessible seats; the accessible seating is not dispersed so as to provide persons with mobility impairments the same range of seating choices as is provided to persons without disabilities ... and the routes, toilet rooms, and concession stands are inaccessible."

I was under the impression this case had to be tried or something; can the DoE unilaterally impose a punishment like this? Anyone out there have an idea how significant an event this is?

If you could create some sort of time vortex that inverted the order of the quarters in the Minnesota game Saturday, there would be no complaints from even the grumpiest Michigan fans out there. After


are major 4 theories, these are:

The Modesty Theory: The word “modesty” comes from the Latin word modestus which means “keeping within measure”. This theory familiar to the Mesopotamian legends of the garden of Eden and even seduction by the serpent holds that clothing was originally donned to conceal the genital organs from a sense of shame, modesty, embarrassment, or some other forms of sexual emotions. From this beginning it is assumed has grown the practice of covering body more generally as sexual self-consciousness has become more refined. The Immodesty Theory: sexual attraction theory (Westmark 1921) people first wore clothes in order to attract attention to the private parts *DRESS IS A POWERFUL SEXUAL TOOL*This theory popularized by Westermarck and Havelock Ellis, maintains that the intent and purpose ofBibimBob), enjoyable and easy conversation, and company of a dear friend.

Post Halloween shopping with another important friend.

The sheer delight on my kiddo’s face who came running to hug and greet me, as soon as I walked into the classroom for the Halloween party.

This cowboy at Dirt Coffee, for his generosity and friendliness in spirit.

My son presenting a bouquet.

A kindred spirit who goes on adventures, rakes leaves, cleans up vomit, goofs off, and brainstorms writing ideas with me.


Leadership→

I am sure for many of us who have been taught that life is a struggle and we must fight for our existence and win etc , advice on mindfulness seems overly simple and you may have doubts to its efficacy but let me share some insights on how this works to some extent and … Continue reading Solve problems mindfully and grow in love!!!→the full time prescribed. It may take up to several days of continued use to see a relief in symptoms and up to 6 weeks for full benefit. If immediate relief of symptoms (itching) is needed, use other quick-relief medication (such as eye drops containing antihistamines, decongestants, or nonsteroidal anti-inflammatory drugs-NSAIDs) along with cromolyn as directed by your doctor. Tell your doctor if your condition persists or worsens.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use. Keep a list of all your


All posts tagged: Boston art

I’ve been going through some images that I made five or more years ago. Meet You at the Corner (above) is one of them. I just realized I’ve never actually had a print made of it before—tomorrow’s the day!

Chinatown Sky (above) began with a photograph I took here in Boston in Chinatown. I really liked the curve and shape of this building. I thought it could make for an interesting art subject, but sadly, once I had painted the photograph, I just didn’t find the overall piece interesting enough…

My Boston row house inspired painting “After Midnight at Number 3” is finished. I think of it as a narrative painting because it suggests that a story (however mysterious it may be) is unfolding at the[@pone.0061688-Inda1] tested whether reconsolidation mediates memory strengthening and examined its interaction over time. They found that successive reactivations of recent memories by re-exposition to the context of the original memory resulted in reconsolidation that mediated memory strengthening and prevented forgetting; this effect was temporally limited.

We previously demonstrated that reconsolidation of human declarative memories serves both functions [@pone.0061688-Forcato1], [@pone.0061688-Forcato2]. Our paradigm consists of a verbal learning task (lists of five pairs of nonsense syllables) using a training process (L1-training) on Day 1 of the experiment. After the declarative memory is consolidated, it can be labilized via presentation of a specific reminder. The memory then passes through a stabilization process. To reveal the presence of this process, we used a second learning task (L2-training), which interfered with the re-stabilization phase


session of the list of syllables (List 1; **L1**), Rc for the cue reminder, and L1-TS for the testing session of L1. Groups differ in the number or presence or absence of reminders that they received on Day 2. Group NR 7d without any reminder presentation, Group RcX1 received a cue reminder, Group RcX2 received two cue reminders. **A.2) Testing Session.** Mean number of total errors +/− SEM on Day 7. \*,p\<0,05. Black bar stands for Group NR 7d, Light Gray bar for Group RcX1 and White bar for Group RcX2. **A.3) Error Type. A.3.1)** Mean number of Void-Type error errors +/− SEM on Day 7. **A.3.2)** Confusion-type errors. **A.3.3)** Intralist-type errors. Symbols as above.](pone.0061688.g001){#pone-0061688-g001}

### One or two cue-reminders improve performance on Day 7 {#s2a1}

A repeated-measures ANOVA revealedby trial interaction (F(8,160) = 0,984, p = 0,450). An analysis of the percentage of correct responses given during the last four training trials yielded no significant difference between the groups at training ([Figure S4](#pone.0061688.s004){ref-type="supplementary-material"}.G inset, F(1,18) = 0,970, p = 0,759).

Next, we analyzed List 1 performance at testing. The number of errors made for List 1 were similar in both groups ([Figure 3B](#pone-0061688-g003){ref-type="fig"}.3 NR 8d and RcX1-L2 F(1,18) = 1,791, p = 0,204). The analysis of the type of errors made revealed no significant differences between the groups for void-type and intra-list errors; however, significant differences for confusion-type errors were observed ([Figure 3B](#pone-0061688-g003){ref-type="fig"}.4.2, p = 0,911, p = 0,187 and p = 0,034, respectively). Despite the absence of significant differences, confusion-type errors may indicate that there was an effect of the treatment, although, this effect may not have been large enough to be reflected in


of HPC neurons, which act as an index of neocortical neurons that attend to the information and binds them into a coherent representation. The MTT also argued that reactivating a memory leads to the re-encoding and expansion of previously stabilized memory. Hence, this alteration of previously stored memories as a function of reactivation, provides a theoretical framework for understanding the reconsolidation effects [@pone.0061688-Nadel2].

Finally, the schema assimilation model (SAM, [@pone.0061688-Tse1]) argues that newly acquired memories are not stored in isolation, but rather, new memories are gradually incorporated into a "schema," or an organization of related knowledge. Using this framework the results reported here might imply that when the trace is neocortical (SCT), an ensemble of multiple traces (MTT), or the rapid incorporation of new information into the preexisting schemaRcX1-- L2: Subjects received the training session (List 1) on Day 1, the cue reminder on Day 2 and five minutes later learned the List 2 and were tested on Day 3. Group Rcx2: The protocol was the same as Group RcX1 but they received the cue-reminder two times separated. Group Rcx2-- L2: The protocol was the same as Group RcX2 but they learned List 2 five minutes later. Group CT -- L2: Subjects learned List 2 on Day 2 and were tested on Day 3.

### Experiment 3A {#s4c3}

*(n = 10).* Group NR 8d: As in experiments 1A and 2 but were tested on Day 8. Group RcX1: Group RcX1: Subjects received the training session (List 1) on Day 1, the cue reminder on Day 7 and were tested on


of total errors in the four last actual trials. Black bar stands the Group CT-L2 and gray bar for the Group RcX1-L2.

(TIF)

######

Click here for additional data file.

######

Learning curves. Mean number of errors +/−SEM per trial on Day 1. On the first trial the List is presented for the first time.**G) Experiment 3.B.** ***List 1 Training.*** Black rombhus stands for the Group NR 8d and gray squares for the Group RcX1-L2. *Inset*. Mean number of total errors in the four last actual trials. Black bar stands for Group NR 8d and gray bar for the Group RcX1-L2. **H) Experiment S2.** Black rombhus stands for the Group NR 3d and White squares for the Group NR 8d. *Inset*. Mean number of total errors in the four last actualr.Intn(10) != 0 {
		this.XXX_unrecognized = randUnrecognizedUnrecognizedgroup(r, 6)
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func NewPopulatedA(r randyUnrecognizedgroup, easy bool) *A {
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			if r.Intn(2) == 0 {
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		}
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		this.Group2 = NewPopulatedOldWithGroup_Group2(r, easy)
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	if !easy && r.Intn(10) != 0 {
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	return this
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func NewPopulatedOldWithGroup_Group1(r randyUnrecognizedgroup, easy bool) *OldWithGroup_Group1 {
	this := &OldWithGroup_Group1{}
	if r.Intn(10) != 0 {
		v6 := int64(r.Int63())
		if r.Intn(2) == 0


on iTunes.

I’m alive – and the world shines for me today
I’m alive – suddenly I am here today
Seems like forever (and a day), thought I could never (feel this way)
Is this really me? I’m alive, I’m alive

I’m alive – and the dawn breaks across the sky
I’m alive – and the sun rises up so high
Lost in another world (far away), never another word (till today)
But what can I say? I’m alive, I’m alive, I’m alive

Suddenly came the dawn (from the night), suddenly I was born (into light)
How can it be real? I’m alive, I’m alive, I’m alive

I’m alive – and the world shines for me today
I’m alive – suddenly I am here today
Seems like forever (and a day), thought I could never (feel this way)
Is this really me?a device used by Cesare's scribes to decrypt the messages used by Cesare's scribes and the Crows. Machiavelli then decides to chase one of Cesare's men, a bookkeeper running a ledger containing detailed information on Cesare's plans. Machiavelli sends an Assassin, who follows the bookkeeper to his hideout and steals the ledger. While reading the ledger, Machiavelli discovers the existence of Il Corvo, the Grandmaster of the Crows It also revealed that there was a Crow hideout in Rome, and that the Crows were planning something involving the nobles. Sirus then insists on staying in Rome, where he would intercept Crow messengers.

A few months later, Sirus sends a letter saying he knows where Il Corvo is hiding, and requests an Assassin to help him gather more information. The


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  fracture, use of the compression ratio of the cross-sectional area may effectively avoid bias associated with sex and ethnicity. In our study, compression ratio of sagittal diameter and cross-sectional area were associated with nerve injury. However, multivariate analysis showed that compression ratio of sagittal diameter had a stronger correlation with the severity of nerve damage than did the compression ratio of the cross-sectional area.

Rotation of retropulsion bony fragments in the vertebral canal as well as change in canal volume was taken into account. Thoracolumbar burst fractures create bony fragments of the posterior wall, which are retropulsed into the vertebral canal. Guerra et al. \[[@CR26]\] found retropulsion and rotation of bony fragments, a phenomenon that was later confirmed on CT. Flipping of bone fractures may reflect the severity of


what do you think happened, Doc?" "You know something?" "I don't really know." "Hey." "You okay, son?" "Yeah, yeah." "I just have never done this, at least, with the bag and everything." "Don't feel bad." "When I first got the contract as coroner for the county," "I didn't sleep very well at night myself." "Yeah, but then after a while it's not so bad." "Stan, I brought half the people in this county into the world, and it felt right, going the other way never does." "Come on." "Let's get Rolf out of here." "Son of a bitch!" "I'm not lost." "I don't want to fight, okay?" "But look, we must be lost." "We're on a dirt road too small to even put on the map." "What thehere." "Wayne." "Yeah, okay." "The state police are coming as soon as they can, but they've got a big pile-up on the interstate right now,  and they're shorthanded." "Listen, Luanne, we're stuck in Clyde's bus out at Parker's place." "You got to get us help immediately." "Do you understand?" "Okay, Wayne." "I'm gonna do everything that I can." "So, just take care." "Make it happen, Luanne." "Make the call and get us help." "Listen, I'm gonna try and get everybody up to Betty's as soon as possible." "Luanne, do you copy?" "Wayne?" "Wayne, it's Cynthia." "Hey!" "Look out, Wayne!" "Wayne, do you copy?" "Wayne?" "Everybody get to the truck, now!" "Come on, girls!" "Let's go!" "Come on!" "Come on!" "Let's go." "Yeah!" "Wait." "Wait." "What about Coach?"


heart of Budapest and later went international, where the leads always converge on Rogán’s confidante, Balázs Kertész.

Antal Rogán showed up first at number 3, Aulich utca on that chilly November morning a year ago. A couple of weeks earlier he had moved from being leader of the Fidesz parliamentary group to head of the prime minister’s cabinet office. The dark-coloured ministerial minibus pulled in at about 09:50. Rogán made phone calls from the car while for some five minutes his men wandered in the street, waited at the main entrance, and scanned the passers-by. When the minister finally stepped out at 09:55, his minder made some terse remarks to bystanders while opening the door. The minister – tapping on his phone and wearing a blue body-warmer over hisin 2003 where for the first time the names of Rogán and Kertész came up together: the K&H broker scandal. A parliamentary committee was established to investigate the case – which, of course, came to nothing – and the relevant parliamentary decree from 2003 lists Rogán, Kertész, and their later boss László Kelemen, among questions related to involvement in the case.

Extracts from the parliamentary decree:

27. Is there any basis to press reports according to which Antal Rogán, with the cooperation of the FIDESZ Hungarian Civic Union representative and District V local government FIDESZ councillor Balázs Kertész, was the beneficiary in certain of Attila Kulcsár’s financial transactions? What is the significance in terms of the given case of the fact that Balázs Kertész worked in the law practice of


Kertész had nothing to do with the 245-square metre, five-bedroom, third floor property at number 3, Aulich utca, it was among the district’s assets. According to the evaluation that can be found on the District V website, the property was worth 52 million forints in 2008. At the time it was not listed as an apartment, merely as “sundry premises”.

In October 2010, a month after Monavis was registered as a company, the “sundry premises” on Aulich utca were reclassified as a residential apartment. This would have had to be initiated by the Rogán-led local government. A real estate expert told Index: at this time, the value of the property could have doubled almost immediately. However, a year later, in November 2011, District V sold the flat for muchKempinski hotel on Erzsébet tér – Árpád Habony’s girlfriend even had a painting exhibition there. Searching the Facebook gallery of a Syrian jewellery shop in the hotel, we stumbled upon Balázs Kertész himself.

Photos from last year can be found in this album: Kertész wears a striped blue jacket and white-spotted blue tie while attending a dinner at the Swiss embassy and looks at watches with a price tag of 40-100 million forints. It is interesting that, according to the data contained in the June statutes of Opal Zrt, Balázs Kertész – who is a member of the supervisory board of the company – has an address in Switzerland, while Átlátszó recently linked him to the renovation of a Swiss-owned villa on Gellérthegy. Kertész’s representative denied to that publication


in autumn 2012, with Rogán as parliamentary group leader, it signed a legal advisory contract with the Kosik Law Practice

Prime minister’s cabinet office: after he was made a minister, the ministry also contracted with Kosik and company, in the first half of 2016.

District V: The ownership, disposal and housing committee of the formerly Rogán-led District V commissioned Kosik and company in 2015 to prepare an out-of-court settlement.

After our inquiries had led us to this point, we attempted to get in contact with Balázs Kertész himself. But when we phoned the central number for Kosik’s office – since Kertész officially still works for Kosik – the staff member who picked up responded to our surprise call by asserting that Kertész did not work there. Then in response to our2013, the government loosened its grip on the mandate and allowed families to start having two children but only if either parent is an only child. Though it was liberating, less than the expected number of couples opted to apply for a second child.

The Accumulated Result is not a Pretty One:

The gender imbalance hang-up mixed with the attributed sexism leads to a very deadly (and lonely) combination. Like many of its Asian neighbors, China has a social issue with the prioritization of males. If couples were forced to only have one child, it was imperative for some that that child be male. Because of this, some couples would choose to abort the fetus once knowing that the offspring is female. The problem was so common that the government