// Conquer a New Region, ACM/ICPC Changchun 2012, UVa1664
// 陈锋
#include <cassert>
#include <cctype>
#include <cstdio>
#include <functional>
#include <algorithm>
#include <string>
#define _for(i,a,b) for( int i=(a); i<(b); ++i)
#define _rep(i,a,b) for( int i=(a); i<=(b); ++i)
using namespace std;
const int MAXN = 200000 + 4;
typedef long long LL;
struct Edge{
    int from, to, weight;
    bool operator<(const Edge& rhs) const { return weight > rhs.weight; }
};

Edge edges[MAXN];
LL WS[MAXN], Pa[MAXN], Cnt[MAXN]; // WS[i]表示以i为根节点的树的边权和
int main(){
    int N;
    while(scanf("%d", &N) == 1 && N){
        _for(i, 1, N) {
            Edge& e = edges[i];
            scanf("%d%d%d", &(e.from), &(e.to), &(e.weight));
Symmetry Transition Preserving Chirality in QCD: A Versatile Random Matrix Model.
We consider a random matrix model which interpolates between the chiral Gaussian unitary ensemble and the Gaussian unitary ensemble while preserving chiral symmetry. This ensemble describes flavor symmetry breaking for staggered fermions in 3D QCD as well as in 4D QCD at high temperature or in 3D QCD at a finite isospin chemical potential. Our model is an Osborn-type two-matrix model which is equivalent to the elliptic ensemble but we consider the singular value statistics rather than the complex eigenvalue statistics. We report on exact results for the partition function and the microscopic level density of the Dirac operator in the ϵ regime of QCD. We compare these analytical results with Monte Carlo simulations of the matrix model.


Q:

Is it possible to determine the number of characters used for a password used to encrypt a file with AES 128?

I lost a password for an ethereum wallet at the end of 2016. Computer immediately shutdown and password was not recoverable.
I know there are many potential avenues for narrowing my search for what my password could have been, but I am wondering if the number of characters can be determined from the encrypted file?
I dont know if this would make a difference but it was an ethereum wallet, using Geth

A:

No. Password cannot be used to encrypt anything directly unless it is exactly of a certain size, and then it will be likely weak. Encryption passwords are hashed, with a slow hash hopefully, and the output is usedJun 27 Grillstock Bristol – Because Real BBQ is Served on a Tray

Now, I don’t normally write reviews. Not because I lack mental capacity in that particular area. I lack mental capacity across a whole spectrum of subjects, that much is obvious. Everyone loves rating meat though. That may sound like a sweeping generalisation and by all accounts it is – but don’t tell me you don’t feel the intense pressure of hungry eyes whilst cooking at even the smallest and most casual of BBQ’s.
But Grillstock are professionals – and I shall show no remorse.

The Lock Jaw Trio

All three of us visiting went for the Lock Jaw burger so called due to its height. There were the 2 beef patties, some brisket, a handful of pulled pork, a


please don’t be put off by the name. They sound like you have been lumbered with the end piece of a stale loaf of bread, but they are the best bit of the brisket. The only downside of burnt ends is that there has to be something in the middle of the meat before the pit master can get to the other side and get more burnt ends. The brisket is in the way and you’re just going to have to eat it.

The Lockjaw burger patty itself wasn’t anything ground-breaking. It was a perfectly adequate burger, but when placed adjacent to say a rack of babyback ribs and a mound of pulled pork you see a burger for what it really is: A vehicle for cheaper cuts of  proxy_pass http://localhost:1337/;
    proxy_ssl_session_reuse off;
    proxy_set_header Host $http_host;
    proxy_redirect off;
}

# pass the PHP scripts to FastCGI server listening on 127.0.0.1:9000
#
#location ~ \.php$ {
#   include snippets/fastcgi-php.conf;
#
#   # With php7.0-cgi alone:
#   fastcgi_pass 127.0.0.1:9000;
#   # With php7.0-fpm:
#   fastcgi_pass unix:/run/php/php7.0-fpm.sock;
#}

# deny access to .htaccess files, if Apache's document root
# concurs with nginx's one
#
#location ~ /\.ht {
#   deny all;
#}

listen [::]:443 ssl ipv6only=on; # managed by Certbot
listen 443 ssl; # managed by Certbot
ssl_certificate /etc/letsencrypt/live/example.com/fullchain.pem; # managed by Certbot
ssl_certificate_key /etc/letsencrypt/live/example.com/privkey.pem; # managed by Certbot
include /etc/letsencrypt/options-ssl-nginx.conf; # managed by Certbot
ssl_dhparam /etc/letsencrypt/ssl-dhparams.pem; # managed by Certbot

}
This is my Parse Server init
var api = new ParseServer({
databaseURI: 'mongodb://localhost:27017/admin',
cloud: __dirname + '/cloud/main.js',
appId: 'appId',
masterKey: 'masterKey',
serverURL: 'https://example.com:1337/parse',
liveQuery: {
classNames: ["Posts", "Comments"]


     41              29          61            6

  Kip et al[40](#jah31903-bib-0040){ref-type="ref"}                  USA               1999   Post hoc analysis of the BARI trial       Anatomic: Angiographically significant lesions were defined as \>50% stenoses in a vessel \>1.5 mm, as measured by electronic calipers. A reduction in stenosis of ≥20% with residual stenosis of \<50% and TIMI grade 3 flow defined  64            6

  Srinivas et al[46](#jah31903-bib-0046){ref-type="ref"}             USA               2007   Observational study                       Anatomic: CR required that at least 1 lesion had to be treated in each of the major territories with diameter stenosis \>50%


              (CR vs IR) MACCE 34.7% vs 45.1%; adjusted hazard ratio \[HR\] 0.65, 95% CI 0.44‐0.95, *P*=0.03; all‐cause death adjusted HR 0.48, 95% CI 0.29‐0.80, *P*\<0.01

  Song et al[45](#jah31903-bib-0045){ref-type="ref"}                 (CR vs IR) MACE HR 0.64, 95% CI 0.46‐0.88, *P*=0.01; revascularization HR 0.61, 95% CI 0.42‐0.90, *P*=0.01; death HR 0.87, 95% CI 0.48‐1.57, *P*=0.64; MI HR 0.62, 95% CI 0.23‐1.67, *P*=0.35. The rate of periprocedural MI and stent thrombosis was comparable in the 2 cohorts (4.7% in the CR group vs 3.6% in the IR group, *P*=0.42; 1.6% vs 1.3%, *P*=0.72, respectively)

  Srinivas et al[46](#jah31903-bib-0046){ref-type="ref"}     z\r & = f \big(\R+\i\I\big) = \sin \big(\R+\i\I\big) =
\underbrace{\sin \R \cosh\I}_{:=u} + \i
\underbrace{\cos\R\sinh\I}_{:=v}
\end{aligned}
$$
Therefore
$$
f\l z \r = f\l \xy\r = u\l x, y \r + \i v\l x, y \r,\ \ \text{where} \ \ \
\begin{cases}
u \l x, y \r = \sin \l x \e{3x}  \cos y\r \cosh \l y+\e{3x}\sin y\r
\\
v \l x, y \r = \cos\l x \e{3x}  \cos y\r \sinh \l y+\e{3x}\sin y\r
\end{cases}
$$
Finally, we write
$$
\bbox[5pt, border:2pt solid #FF0000]{\
f\l x,y\r =
\sin \l x \e{3x}\!  \cos y\r \cosh \l y+\!\e{3x}\!\sin y\r + \i
\cos\l x \e{3x}\!  \cos y\r \sinh \l y+\!\e{3x}\!\sin y\r\
}
$$

I hope you can pick it from here and compute the derivative
$$
\frac{\partial{f}}{\partial{\z}} = \frac{1}{2}\bigg(
\frac{\partial{f}}{\partial{x}} + \i\frac{\partial{f}}{\partial{y}}
\bigg)
$$


Apart from adding a home button to your iDevice’s Safari, the tweak also ensures that every time the browser is launched on a jailbroken iPhone, iPad or iPod touch, it opens to your defined homepage. This can prove to be a useful feature for a lot of users, even if they don’t want a Home button in the browser. Setting up a homepage like Google.com will make Safari launch in less time, as by default it tries to load the page that was last opened, and that often takes time.

After its installation, you will see that HomeSafari adds a new menu of its own to the stock Settings app. In this menu, it is possible to set a homepage for Safari, and you can also toggle on orDistressed Damsels

If I had to pinpoint where exactly I fell in love with “Orange is the New Black”, it would be during one moment, midway through the third episode. In it, the show cuts between two shots of Sophia Burset (played by Laverne Cox) in front of a mirror: in the first, as a male firefighter; in the second, as a female prison inmate. You immediately notice the big changes: Sophia has a new body, new hair, and a prison uniform. But, despite these physical differences, her expression is barely altered. She’s gotten what she wanted, and yet she’s still trapped.

The show is based on Piper Kerman’s memoir, which follows her vertiginous fall from upper middle class fiancée to prison inmate after being implicated in her ex-girlfriend’s drug


fashion and to express one’s thoughts clearly and with grace.

CARITAS (Love) - Union with God through Love

The great commandment of Christ is to love God and to love neighbour. The school community and relationships within it are a special place where this love finds expression.

More than any one word can express (be it love, concern, devotion, compassion, caring), “caritas” is that impulse of the Spirit of Jesus that is expressed in hundreds of kind and gracious ways. It is “active friendship” that encompasses both love of God and neighbour. It is when the head and heart move into action, often with sacrifice.

What does “Caritas” look like?

Being a friend.

Loving deeds.

Service to the community.

Care for the common good.

Sharing of goods (information, resources talents).

Personal interest and support of one another.

Bearing sharedWhen should cardiologists suspect Anderson-Fabry disease?
Anderson-Fabry disease is a lysosomal storage disorder caused by α-galactosidase defects and progressive intracellular accumulation of globotriaosylceramide. The disease can be specifically treated with enzyme replacement therapy. Hemizygous men and heterozygous women can develop cardiac disease. Whereas men experience the most severe clinical phenotype, clinical presentation in women varies from asymptomatic to severely symptomatic. The characteristic cardiac phenotype is left ventricular hypertrophy mimicking sarcomeric hypertrophic cardiomyopathy or hypertensive heart disease. Early or prehypertrophy cardiac involvement may escape detection, unless electrocardiographic clues are present. The cardiac markers that raise suspicion of Anderson-Fabry disease include a short PR interval without a δ wave and a prolonged QRS interval, supraventricular and ventricular arrhythmias, and concentric left ventricular hypertrophy. Extracardiac features include renal failure, corneal deposits, and


==== Current limitations ====
- For HTML emails send in Text+HTML (aka multipart/alternative) we can display
  the HTML version only because it's the first attachment we treat.

==== For a future release ====
- Refactor DB:
-- Mime messages tables (esp. multipart/alternative)
-- Store often used headers as table columns (date, ctype, subject, message_id)
the output of the power supply, and a controller for providing a pulse width modulation (PWM) signal to the power supply. The PWM signal has a controllable pulse width or PWM on-time.
The power supply, which is controllable in response to the PWM signal, includes an input connectable with the source for receiving power from the source, an output connectable with the load for delivering power to the load and a PWM input for receiving the PWM signal.
The voltage sensor provides a first control signal corresponding to the voltage sensed at the power supply output. Similarly, the current sensor provides a second control signal corresponding the current sensed at the power supply output.
The controller is operatively connected to the PWM input of the power supply and to the sensors


liable for injury ... or loss to persons or property that is caused by their negligent failure to keep public... aqueducts, ... within the political subdivision open, in repair or free from nuisance..." thereby constituting an exception to the immunity generally provided to political subdivisions in § 29-12A-4(b)(1) of the Act?
Ruling by the Circuit Court: Yes X No ___
2. If the plaintiffs' claim against the City of Charleston in this case falls within § 29-12A-4(c)(3), does the claim, in turn, fall within the specific exception to liability set forth in § 29-12A-5(a)(16) providing that "a political subdivision is immune from liability if a loss or claim results from [t]he operation of dumps, sanitary landfills, and facilities where conducted directly by a political subdivision?"
Ruling by the Circuit Court: Yesfor summary judgment." Cleckley, Davis & Palmer, Litigation Handbook, § 56(b), at 1119 n. 281. See State ex rel. Pritt v. Vickers, 214 W.Va. 221, 225, 588 S.E.2d 210, 214 (2003) ("Federal `[c]ourts and commentators have acknowledged that no answer need be filed before a defendant's motion for summary judgment may be entertained.' INVST Fin. Group, Inc. v. Chem-Nuclear Sys., Inc., 815 F.2d 391, 404 (6th Cir.1987).").
[8]  During oral arguments, counsel for the Pingleys suggested that discovery could not occur because no answer was filed. As a general matter, our rules of civil procedure permitted the Pingleys to engage in discovery even though an answer had not been filed. See Cleckley, et al., Litigation Handbook, § 30(a), at 733 ("An oral deposition under Rule 30(a) may not


occur until after an action has been properly filed. Rule 30(a) requires a plaintiff obtain leave of court, if the plaintiff seeks to take a deposition prior to the expiration of 30 days after service of process upon any defendant[.]"); id., § 33(a), at 804 ("[Rule 33(a)] provides that interrogatories may be served upon any defendant, without leave of court, with or after service of the summons and complaint upon that party."); id., § 34(b), at 833 ("A plaintiff may, without leave of court, serve a Rule 34(a) discovery request upon any defendant together with service of the summons and complaint or after service of process."). However, we equally understand that, because of the limited time between the filing of the summary judgment motion and when that motionAs the number of samples to be analyzed continue their ever increasing pattern, the importance of automated chemical analysis procedures continues to increase as well. So far for liquid-phase analysis, the major emphasis has been on continuous flow systems. Segmented Continuous Flow Analysis (SCFA) as introduced by Skeggs in 1957 (Am. J. Clin. Pathol., 28, pp. 311-322) was commercialized subsequently by the Technicon Corporation and proved so extraordinarily successful that for years automated liquid-phase analysis was synonymous with the trade name of the Technicon instrument, the Autoanalyzer. More recently, Flow Injection Analysis (FIA), also a continuous flow procedure but without segmentation, has proved to be a formidable contender to SCFA (see U.S. Pat. No. 4,022,575 to Hansen and Ruzicka). Despite the unique ability of FIA to provide reproducible


Analysis" published by Horwood in Sussex, England in 1975 and authored by Foreman et al.) can be considered microscale systems but so far do not find much use in non-clinical laboratories, probably because they are complex and costly systems, e.g., they generally use many test tube-like reaction chambers and transport the chambers from station to station to receive samples and reagents.given parameter values on a
  sequence of wires (subsystems).

Differentiation
^^^^^^^^^^^^^^^

In general, an :class:`Operation` is differentiable (at least using the finite-difference
method) with respect to a parameter iff

* the domain of that parameter is continuous.

For an :class:`Operation` to be differentiable with respect to a parameter using the
analytic method of differentiation, it must satisfy an additional constraint:

* the parameter domain must be real.

.. note::

    These conditions are *not* sufficient for analytic differentiation. For example,
    CV gates must also define a matrix representing their Heisenberg linear
    transformation on the quadrature operators.

For gates that *are* supported via the analytic method, the gradient recipe
(with multiplier :math:`c_k`, parameter shift :math:`s_k` for parameter :math:`\phi_k`)
works as follows:

.. math:: \frac{\partial}{\partial\phi_k}O = c_k\left[O(\phi_k+s_k)-O(\phi_k-s_k)\right].

CV Operation base classes
~~~~~~~~~~~~~~~~~~~~~~~~~

Due to additional requirements, continuous-variable


  :class:`.Variable` instances are replaced by their
        current numerical value.

        Returns:
            list[Any]: parameter values
        """
        # TODO profiling
        def evaluate(p):
            """Evaluate a single parameter."""
            if isinstance(p, np.ndarray):
                # object arrays may have Variables inside them
               if p.dtype == object:
                    temp = np.array([x.val if isinstance(x, Variable) else x for x in p.flat])
                    return temp.reshape(p.shape)
                return p

            if isinstance(p, list):
                # p is assumed to be a list of numpy arrays


``[None, 1]``, indicating the operation has no generator.
        """
        return [None, 1]

    @property
    def inverse(self):
        """Boolean determining if the inverse of the operation was requested."""
        return self._inverse

    @inverse.setter
    def inverse(self, boolean):
        self._inverse = boolean

    @staticmethod
    def decomposition(*params, wires):
        """Returns a template decomposing the operation into other
        quantum operations."""
        raise NotImplementedError

    def      self.grad_method is None
            ), "An operation may only be differentiated with respect to real scalar parameters."
        elif self.par_domain == "A":
            assert self.grad_method in (
                None,
                "F",
            ), "Operations that depend on arrays containing free variables may only be differentiated using the F method."

        # check


array: eigenvalue representation
        """
        raise NotImplementedError

    @property
    def eigvals(self):
        r"""Eigenvalues of an instantiated diagonal operation.

        The order of the eigenvalues needs to match the order of
        the computational basis vectors.

        **Example:**

        >>> U = qml.RZ(0.5, wires=1)
        >>> U.eigvals
        >>> array([0.96891242-0.24740396j, 0.96891242+0.24740396j])

        Returns:
          *instantiated* channel,
        please use the :attr:`~.Operator.kraus_matrices` property instead.

        Returns:
            list(array): list of Kraus matrices
        """
        raise NotImplementedError

    @property
    def kraus_matrices(self):
        r"""Kraus matrices of an instantiated channel
        in the computational basis.

        ** Example**

        >>> U = qml.AmplitudeDamping(0.1, wires=1)
        >>> U.kraus_matrices
        >>> [array([[1.


      """
        return super().eigvals

    def __init__(self, *params, wires=None, do_queue=True):
        # extract the arguments
        if wires is None:
            wires = params[-1]
            params = params[:-1]

        super().__init__(*params, wires=wires, do_queue=do_queue)

    def __repr__(self):
        """Constructor-call-like representation."""
        temp = super().__repr__()

        if self.return_type is None:
           """
        return Wires([o.wires for o in self.obs])

    @property
    def data(self):
        """Raw parameters of all constituent observables in the tensor product.

        Returns:
            list[Any]: flattened list containing all dependent parameters
        """
        return [p for sublist in [o.data for o in self.obs] for p in sublist]

    @property
    def num_params(self):
        """Raw parameters of all constituent observables in the tensor product.


contains only standard observables.
                    self._eigvals_cache = np.kron(self._eigvals_cache, pauli_eigs(len(list(g))))
                else:
                    # Subgroup g contains only non-standard observables.
                    for ns_ob in g:
                        # loop through all non-standard observables
        """
        diag_gates = []
        for o in self.obs:
            diag_gates.extend(o.diagonalizing_gates())

        return diag_gates

    @property
    def matrix(self):
        r"""Matrix representation of the tensor operator
        in the computational basis.

        **Example:**

        Note that the returned matrix *only includes explicitly
        declared observables* making up the tensor product;
        that is, it only returns the matrix


 if len(mats) > 1:
                # multiply all unitaries together before appending
                mats = [multi_dot(mats)]

            # append diagonalizing unitary for specific wire to U_list
            U_list.append(mats[0])

        # Return the Hermitian matrix representing the observable
        # over the defined wires.
        return functools.reduce(np.kron, U_list)

    def prune(self):
        """Returns a   """A mixin base class denoting a continuous-variable operation."""

    # pylint: disable=no-member

    def heisenberg_expand(self, U, wires):
        """Expand the given local Heisenberg-picture array into a full-system one.

        Args:
            U (array[float]): array to expand (expected to be of the dimension ``1+2*self.num_wires``)
            wires (Wires): wires on the device the array ``U`` should be expanded
                to apply to

        Raises:


matrix is the wrong size {}.".format(self.name, U_dim))

        if len(wires) == 0 or len(self.wires) == len(wires):
            # no expansion necessary (U is a full-system matrix in the correct order)
            return U

        if self.wires not in wires:
            raise ValueError(
                "{}: Some observable wires {} do not exist on this device with wires {}".format(
                      Raises:
            RuntimeError: if the specified operation is not Gaussian or is missing the `_heisenberg_rep` method

        Returns:
            array[float]: :math:`\tilde{U}`, the Heisenberg picture representation of the linear transformation
        """
        p = self.parameters
        if inverse:
            if self.par_domain == "A":
                # TODO: expand this for the new par domain


minute thought puzzle per deck.

My friend and I played through some of a tutorial for the Myth boardgame. Lots of stuff going on in that. Because of hanging out with him, I got to thinking about playing/running a simple AD&D game. So, I went to my stack of old modules and … couldn’t pull out a module from what was a stack of all sorts of things. Instead, I pulled out Greyhawk Adventures. Yup. The AD&D hard bound book for AD&D/AD&D2e. Because people who write blogs like these have this sort of thing just lying around.

I actually read some of it. I looked at the adventures – I guess I’m the sort of jaded gamer who is the target audience for zero level play except I don’t havewhen I feel like it. I could have played Type P, but didn’t. I could have played boardgames, but didn’t. I could have suggested something, but didn’t. I could have pushed for us doing something with the Conan RPG once I had a better idea when I was going to be at the con, but didn’t.

And, yet, I consider what I do as an activity of gaming. Before I got into Shadowfist, some 20 years after it came out, I would watch people play because I knew the people. I also played every few years, but, mostly, I watched people play. I didn’t glean a ton from that, but I may have gleaned some tiny amount and I could have more-gleaned.

There are some games I ultraglean from watching.


possible that I would have final print cards by November) and not anything to do in the mornings when there are no True D/G events, I expect to set up shop in open gaming or wherever and demo Traveller to those who wish to be exposed to a game so brilliant it like radiates UHEGRs or UHECRs or whatever (latter is more searchable if you don’t 说 my lingo).Israel gets sent to jail. "We are very proud that we are stone throwers. I'm one of them. Now I became a little bit older, but I stay resistant in the name of my kids," he continued.

The Palestinian diplomat later told the students about his own past as a stone-thrower during the first intifada. "I was in high school. I never missed an opportunity to throw stones. This is our life. We develop our resistance every day. We're proud of it," he said.

Abushawesh was speaking to a group of international relations students from McGill University who were at the UN for a tour and a series of meetings as part of their program.

Abdallah Abushawesh

The students also met with Palestinian envoy to the UN, Riyad Mansour, who told them


about Palestinian efforts to be recognized as a state by the UN.

"There's a country in the Security Council, the US, which won't allow us to realize what's ours, and it is blocking us for political and ideological reasons, and not for legal reasons," Mansour said.

Israel's Ambassador to the UN, Danny Danon, slammed Abushawesh's comments, saying, "The Palestinians are no longer trying to hide the truth. The Palestinian leadership and its representatives are inciting against Israel and openly encouraging terrorism. The international community must not allow it."

"It cannot be that inside the UN, which is supposed to make peace and protect human rights, a diplomat will incite to violence and terrorism, which wound and even kill innocent Israelis," Danon added.A Failure to Discern: Burns & Novick’s “The Vietnam War” is Bad History

In the first part of my review of the Ken Burns and Lynn Novick PBS documentary “The Vietnam War”, I lamented the absence of voices and perspectives that would give the documentary a sense of proportion as it evaluated the purpose and prosecution of the war. At the end of the documentary, we find, perhaps, the reason for this. “The Vietnam War,” the narrator tells us, “was a tragedy immeasurable and irredeemable.” It appears that the producers, here, are giving away their game. There is no balanced perspective because balance is not to be found in the irredeemable.

But all is not lost, for we are reassured that “meaning can be found in the individual stories” of


Vietnamese fought well. Indeed, having blunted the communist thrust, they recaptured territory that had been lost to Hanoi. Finally, so effective was the eleven-day “Christmas bombing” campaign (LINEBACKER II) later that year that the British counterinsurgency expert, Sir Robert Thompson exclaimed, “you had won the war. It was over.”

Of course, three years later, despite the heroic performance of some ARVN units, South Vietnam collapsed against a much weaker, cobbled-together NVA offensive, mainly because of an act that still shames the United States to this day: the congressional decision to cut off military and economic assistance to South Vietnam. Subsequently, President Nixon resigned over Watergate and his successor, constrained by congressional action, defaulted on promises to respond with force to North Vietnamese violations of the peace terms.

So what areis time-consuming work as the bivalves have often grown into bunches of bivalves, which will then have to be separated, and other organisms, e.g. starfish, and possible unwanted floating material, e.g. plastic bags and drift wood, must also be removed manually. Thus, there is a need for making some operations related to the farming of bivalves more efficient and automated to a greater extent.
Due to the small mesh width of the seine, the use of fine-meshed seine may have the effect that the farmed bivalves will grow tight together in a short time, so that water rich in oxygen and nutrients is prevented from flowing freely through the bivalve collecting device, and the farmed bivalves thereby will not have the required growing conditions.


Michael Owen: Premier League superstar

In a career that’s been blighted by injury, former England striker Michael Owen has continuously shown that he’s got an eye for goal.

Whether it’s playing domestically in the Premier League or La Liga, on the European stage in the old UEFA Cup or Champions League, or on the international stage for the Three Lions, Owen has consistently performed at the highest level.

And yet, this great striker’s career could be coming to a premature end, with the 32-year-old currently without a club and unwilling to drop down to the Championship.

"If a good opportunity doesn’t come my way then so be it. At this stage of my career it has to be something that I’m going to enjoy doing," he wrote on Twitter.

"Not being disrespectful whenWould Liverpool welcome the return of a former hero who is clearly still capable of finding the back of the net.

Everton have been linked in the past – would Owen consider the Toffees despite his links with the Reds. If it’s the only offer on the table, surely the 89-cap international can’t afford to be picky.

Newcastle are unlikely to take him back, even with a new manager in the shape of Alan Pardew, but what about the promoted clubs? Reading, Southampton and West Ham could all use the experience of Owen, even if they used him sparingly.

Spurs aren’t exactly bulging with strikers, even if Emmanuel Adebayor completes his move, whilst a case could be made for Aston Villa, QPR, Sunderland and Wigan to try and bring the player


of a quadratic invariant gap $\Uf$ such that $\Uf\cap \uc$ is a Cantor set.

The convex hull $\Qf$ of $Q$ in the plane is called the *Principal Quadratic Parameter Gap* (see Figure \[fig:Qf\]); it is similar to the Main Cardioid of $\Mc_2$.

![The Principal Quadratic Parameter Gap[]{data-label="fig:Qf"}](Qf.eps){height="6cm"}

Let us now introduce some analytic notions. Fix $\la$ with $|\la|\le
1$. The *$\la$-connectedness locus $\Cc_\lambda$* is defined as the set of all $f\in\Fc_\la$ such that $K(f)$ is connected, equivalently, such that $[f]\in\Mc_3$. This is a full continuum [@BrHu; @Z] (a compact set $X\subset\C$ is *full* if $\C{\setminus}X$ is connected). For every polynomial $f\in\Fc_\la$ and every angle $\al$, we define the *dynamic ray* $R_f(\al)$. Also, for every angle $\theta$, in the parameter plane of $\Fc_\la$ we define the *parameter ray* $\Rc_\lambda(\theta)$. We use rays to$\Fc_\la{\setminus}\Pc_\la$, the points $\om_1(f)$ and $\om_2(f)$ depend holomorphically on $f$ as $f$ moves through $\Wc$. Observe that if $f\in \Fc_\la {\setminus}\Cc_\la$, then $\om^*_2(f)\in
V_f$. Then the map $\Phi_\la(f)=\phi_f(\omega^*_2(f))$ is a conformal isomorphism between the complement of $\Cc_\la$ in $\Fc_\la$ and the complement of the closed unit disk [@BH]. This isomorphism can be used to define *parameter rays*. Namely, the ray $\Rc_\lambda(\theta)$ is defined as the preimage of the straight ray (unbounded radial segment) $\{re^{2\pi i\theta}\ |\ r>1\}$ under $\Phi_\lambda$. We emphasize here that for *dynamic rays* we use the notation $R(\cdot)$ (with possible subscripts and superscripts) while for *parameter rays* we use the notation $\Rc(\cdot)$ (with possible subscripts). This is consistent with our convention to use the calligraphic font for parameter space objects. We have $f\in\Rc_\lambda(\theta)$ if and only


Say that $\gf$ is of *type A* (for adjacent“) if $\gf$ has only one major, and $\gf$ is of *type B* (for bi-transitive”) if $\gf$ has two majors that belong to the same $\si_3$-orbit of edges. Finally, we say that $\gf$ is of *type D* (for disjoint") if $\gf$ has two majors, whose $\si_3$-orbits are disjoint (except for common endpoints). Every finite invariant gap must be of one of these three types.

Let $A\subset \uc$ be a finite invariant set. Then we associate with it a unique *rotation number* $p/q$ if there is an orientation preserving homeomorphism of the circle that conjugates $\si_3|_A$ with the restriction of the rotation by the angle $p/q$ onto an invariant subset of $\uc$. We also talk about rotation numbers of periodic angles andeach integer $r>0$.

Let $p(b,z)=a_1(b)z+\dots+a_N(b)z^N$ be a polynomial such that the degree of $a_j(b)$ is at most $j-1$, for every $j$. It follows that $p(b,z)^k=c_k(b)z^k+\dots+c_{Nk}(b)z^{Nk}$, where the degree of each $c_i(b)$ is at most $i-k$ for each $i\ge k$. Thus, $f_{\la, b}(p(b,z))=\lambda p(b, z) + b p^2(b,z) + p^3(b,z)$ can be written as $d_1(b)z+\dots+d_{3N}(b)z^{3N}$, where the degree of each $d_i(b)$ is at most $i-1$. The result follows.

Proposition \[P:ray0stable\] deals with rays landing at parabolic points.

\[P:ray0stable\] Suppose that an external ray $R_{f_{\la,b_*}}(\theta)$ with periodic argument $\theta\in\R/\Z$ lands at $0$, and $T_{p/q}(b_*)\ne 0$. Then, for all $b$ sufficiently close to $b_*$, the ray $R_{f_{\la,b}}(\theta)$ lands at $0$.

External and quadratic-like rays of polynomials in $\Fc_\la{\setminus}\Cc_\la$ {#ss:exteql}
------------------------------------------------------------------------------

In this subsection, $\lambda$ is a complex number of modulus at most 1. We study the parameter


$R^e_f(\be^-)$ land at a fixed point $z$; we have $z=0$ unless $(\ta_1,
            \ta_2)=(\frac23, \frac56)$ or $(\frac16, \frac23)$.

Except for the case when $\gf=\ol{0 \frac12}$, the set $\gf$ is a gap.

We first prove that (2) implies (1). Assume that $\vk\in
[\theta_1,\theta_2]$. Then, by Proposition \[p:land-endholes\], the rays $R^e_f(\theta_1+\frac 13)^-$ and $R^e_f(\theta_2+\frac 23)^+$ land at a common point, as desired. If (b) holds, the claim follows immediately.

Assume now that (1) holds. Denote the external rays containing $R_f(\theta_1+\frac 13)$ and $R_f(\theta_2+\frac 23)$ and landing at a common point $z$ by $R^e_1$, $R^e_2$; then, by Lemma \[l:land-in-k\], we have $z\in K(f^*)$. Suppose that $\vk\not\in [\theta_1,\theta_2]$, and prove that (b) holds.

To begin with, consider the case when $(\ta_1, \ta_2)=(\frac23,
\frac56)$ so that $(\theta_1+\frac 13, \theta_2+\frac(say, the former) fails to land at $0$. The ray $R_{f}(\theta_1+\frac 13)$ has to land somewhere, say, at a point $z\ne 0$. The point $z$ is repelling or parabolic. It cannot be repelling because then, by Lemma \[l:rep\], for polynomials $g$ sufficiently close to $f$ the ray $R_g(\theta_1+\frac
13)$ will have to land at a point close to $z$ while, by Proposition \[p:W-spec2\], there are polynomials $g$ arbitrarily close to $f$ such that $R_g(\theta_1+\frac 13)$ lands at $0$, a contradiction. On the other hand, by the Fatou–Shishikura inequality, the point $z\ne 0$ cannot be parabolic either (observe that both critical points of $f$ are in parabolic domains at $0$).

A choice of the combinatorial rotation number $p/q$ provides a classification of holes of $\Qf$ into *special* holes and *non-special* holes.

\[d:spec-hol\]


23})$. The existence of such a quadratic gap is a consequence of Theorem \[T:ParDynHoles\]. It is well-known (see, e.g., [@BOPT]) that there is a continuous projection $\psi_{\Uf}:\Uf'\to\uc$ that identifies the endpoints of every arc in $\uc{\setminus}\Uf'$ and that semi-conjugates the mapping $\si_3:\Uf'\to\Uf'$ with the mapping $\si_2:\uc\to\uc$. Apply this projection to the vertices of $\gf_f$ (by definition of $\Uf$, all vertices of $\gf_f$ belong to $\Uf'$). We obtain a $\si_2$-invariant finite set of points of $\uc$ permuted by $\si_2$ as a combinatorial rotation with rotation number $p/q$. However, a subset of $\uc$ with these properties is unique. Therefore, it must coincide with the $\psi_\Uf$-image of the $\si_3$-orbit of $\ol{\theta_1+\frac 13}$. It follows that one of the vertices of $\gf_f$ must coincide either with $\ol{\theta_1+\frac 13}$ or with $\ol{\theta_2+\frac 23}$,wakes in $\Fc_\la$ are disjoint from $\cuc_\la$ where $|\lambda|\le 1$. Recall that if $f$ is immediately renormalizable, then we denote by $f^*$ its quadratic-like restriction upon the appropriate planar domain $U^*$.

Parameter wakes are disjoint from $\cu$
---------------------------------------

In this subsection, $\lambda$ is a fixed complex number such that $|\lambda|\le 1$. Recall, that the *main cubioid* $\cu$ is the set of classes $[f]\in\Mc_3$ with the following properties: $f$ has a non-repelling fixed point, $f$ has no repelling periodic cutpoints in $J(f)$, and all non-repelling periodic points of $f$, except at most one fixed point, have multiplier 1. Recall that $\cuc_\la$ is the set of all polynomials $f\in\Fc_\la$ with $[f]\in\cu$. We will need Theorem \[t:fxpt\] when proving that certain polynomials $f\in\Fc_\la$ do not belong to $\cuc_\la$.

We will prove that all parameter wakes in


they land or crash; it contains external rays with arguments from $(\al, \be)$.

By our assumptions, the filled Julia set $K(f)$ is connected, and $f$ lies in some parameter wake $\Wc_\la(\theta_1,\theta_2)$ of some period $k$. The rays $R_f(\theta_1+\frac 13)$ and $R_f(\theta_2+\frac 23)$ land at the point $x_1$, which is either a repelling periodic point (if the parameter wake is non-special), or the parabolic point $0$ (if the parameter wake is special). If the parameter wake is non-special, we are done. Hence we may assume that the parameter wake is special. Set $X_1=\ol{W_f(\ta_1+{\frac13},\ta_2+{\frac23})}\cap K(f)$. Then $X_1$ is a special piece for $f^{\circ k}$ with exit continuum $\{0\}$. By Theorem \[t:fxpt\] applied to $X_1$ and $f^{\circ k}$, the set $X_1$ contains either (1) a non-repelling $f^{\circ k}$-fixed point in $X_1$, whose multiplierFrance, **48** (1920)

L.R. Goldberg, J. Milnor, “Fixed points of polynomial maps. Part II. Fixed point portraits”, Annal. sci. de l’École Normale Supérieure, $4^e$ série, **26**, n$^\circ$ 1 (1993), 51–98

J. Kiwi, *Non-accessible critical points of Cremer polynomials*, Ergodic Theory and Dynamical Systems, **20** (2000), no. 5, 1391–1403.

J. Kiwi, *Wandering orbit portraits*, Trans. Amer. Math. Soc., **254** (2002), 1473–1485.

J. Kiwi, *$\mathbb R$eal laminations and the topological dynamics of complex polynomials*, Advances in Mathematics, **184** (2004), 207–267.

M. Lyubich, *Some typical properties of the dynamics of rational mappings*, Russian Math. Surveys, **38** (1983), no. 5, 154–155.

R. Mañe, P. Sud, D. Sullivan, *On the dynamics of rational maps*, Annal. sci. de l’École Normale Supérieure, $4^e$ série, **16**, n$^\circ$ 2 (1983), 193–217.

C. McMullen, *Complex dynamics and renormalization*, Annals of Mathematics Studies **135**, Princeton University


don’t persuade me to try those stuff, but I find “men walking in high heels” to campaign for end of violence against women rather bizarre. I think that there are better ways to support a cause than this.

OMG you think a guy who has tried on heels would recruit another living soul to suffer them for anything but a good cause! (Busted – but I wear flats – at 6’2″ and 51, I’m too tall & too old for heels: http://www.youtube.com/watch?v=Rb3rr7EknlI )

There are some pretty complicated reasons that people cheat, both men and women. Is it really wise to have a negative blanket term for all of them? Doesn’t that dehumanize them and take away their agency? Unless you mean that only a woman who cheats can bethis, one of which is reappropriation of slut-shaming terms. Many men have participated in SlutWalks worldwide.” I hope my column does not imply that their is a separate or alternative event for men as that would negate male involvement, participation and support in SlutWalks. The Walk A Mile event is a different event, with a different target audience, and a different kind of awareness than is raised in SlutWalk. There are many similarities and space for allyship between their initiatives but ultimately they are not simply alternatives of the same issues. Perhaps the eye catching title my terrific editor chose may be a tad misleading since the SlutWalks welcome participation by men and hence can be called “a slutwalk for women AND men.”

If men are called allies and


large scale. Real Time Strategic Change (RTSC) gets the job done. — The RTSC Principles are the heart of this approach. Each is[Read More…]

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When we love, we can often stumble into loss. Nathan Graziano shares with us the story of one of his first loves, leaving us to reel in the heartbreaking reality that is loving someone with depression.Hybrid electric vehicles make use of a drive motor in addition to an internal combustion engine. Such vehicles are equipped with a high voltage battery to supply power to the drive motor. In certain situations, exposure to high voltage access points should be limited.


water from any part of their housing hints it's time to rebuild or replace the pump.

-If boom sections refuse to turn "on" or "off", be suspicious of control valves. The old push-pull plunger control valves are notorious for sticking after exposure to chemicals. Newer "ball" valves rarely stick, but are mechanical and therefore not immune to damage from time, caustic chemicals and other villains. Use a small screwdriver or feeler guage to see if the valve's electric magnet is magnetized when its switch is activated in the cab. If magnetism is absent, be suspicious of problems with the wiring harness between the valve and the cab. If the valve's solenoid magnetizes when the switch in the cab is activated, then disassemble the valve and see if there's anthat is already built to handle this. If this is a standardized format, then you can also potentially use other libraries/languages to manipulate it. Also, a string-based format means that you have a hope of understanding it just by eyeballing the data; binary formats remove that option.
XML and JSON are two great options here; they're standardized, text-based, flexible, readable, and have lots of library support. They'll also perform surprisingly well (sometimes even faster than Java serialization).

A:

You might try Protocol Buffers, it is a open-source project from Google, it is said to be fast (generates shorter serialized form than XML, and works faster). It also handles addition of new field gently (inserts default values).

A:

You need to consider versioning in your solution. Data incompatibility is a problem you will experience


to San Francisco. Back in Chicago I sought out the rest of her sound, and it's now a staple of my iPod. My favorite song is not off this album actually, but is still good "Us"

I have a large music collection. It makes every listening a discovery. This is true for the next two artists who I discovered on my iPod during my week up at Houghton Lake. The first is the Dear Hunter. This is the side project of the former frontman of The Recieving End of Sirens, this is a massive undertaking to make a 6 album concept with an overarching story. The sounds range from Beach Boys harmony, to the post punk sound that is popular on many alternative stations, to dabblings in Sergeant Pepper'sThe New York Times.

“I’ve met with several of my counterparties and other people, and we’ve begun to have very high-level conversations about TPP," Mnuchin said.

“It’s not a priority at the moment, but it is something the president will consider.”

Mnuchin went on to add that Trump still favors pursuing one-on-one trade agreements with individual countries, but is keeping rejoining a renegotiated TPP as a possibility in the future.

ADVERTISEMENT

The Treasury secretary's remarks follow Trump's statement during a CNBC interview in Davos, Switzerland, last month that he would consider a renegotiated TPP deal if the agreement was made "substantially better" in terms of achieving U.S. trade goals.

"I would do TPP if we were able to make a substantially better deal. The deal was terrible, the way it was structured was terrible.


example of the creation of the actual sound:
    var hitmarkerSound = NSURL(fileURLWithPath: NSBundle.mainBundle().pathForResource("hitmarker", ofType: "mp3")!)

A:

I think you just need to initialize your variables somewhere other than inside the button press methods, so you can see those variables after the method is over. I always heard it "what happens in a method stays in a method..."
So for example I'd put the declarations at the top of your view controller, and stuff them in an array:
var myAudioPlayers = [AVAudioPlayer] //remember arrays start at 0 and go up to n-1
myAudioPlayers[0] = AVAudioPlayer(contentsOfURL: sound1, error: nil)
...
myAudioPlayers[8] = AVAudioPlayer(contentsOfURL: sound8, error: nil)

Then you'd have
@IBAction func hitmarkerButton(sender: AnyObject) {
    audioPlayer[7].prepareToPlay()
    audioPlayer[7].play()
}

And you can use the array to quickly do:
@IBAction func stopPlayingSounds(sender: AnyObject) {
 how many tickets we can sell in advance. Sorry, we can’t do these shows outside.

2. Ticket price will be $25. Everyone must buy tickets in advance. No tickets will be sold at the door. There will be no reselling or third-party tickets sales. All tickets sales are direct to fans from Undertow. Limit 4 tickets per person. We want everyone to have the same chance of getting tickets.

3. We’ll provide the host with a list of everyone coming to the show. The host won’t have to deal with any money and will only need to check people off the list as they arrive. We ask show guests to arrive between 7:00-7:45pm. The shows start at 8pm and we ask everyone to be out of your space by 10pm.

4.


The only thing that bothers me about these cuffs is the unfinished look of the ends of each cuff. Aside from that I love their appearance and I appreciate the durable, soft faux leather. The black metal accents are attractive and practical. They have secure buckle closures that seem like they’d accommodate many wrist sizes. Each cuff is 2″ wide and just over 10″ long.

They can be easily separated while you’re wearing them. There is a lobster claw clip at the end of a chain attached to one cuff that clips to a D-ring on the other cuff. That clip is accessible to the wearer. For anyone looking for more intense restraint this might not be ideal, but for others it may bring peace of mind to knowclose to what they should be -- although the Hispanic sample may be slightly high (20 percent). The partisan and regional breakdowns are good.

Some of the key numbers:

Obama-Romney: 49-47 and 51-44

Heller-Berkley: 49-43, 48-44

Obama: 50-47, favorable/unfavorable

Romney: 45-48, favorable-unfavorable

Those favorabble/unfavorable numbers don't bode well for Romney, on one hand, but also suggest that even if some people don't like the GOP nominee, they still will vote against the president.

Obama is up by only 7 in Clark County and Berkley tied in Clark County among likely voters? Those seem low for both of them. Obama is ahead by 11 in Clark among registered voters, which seems more reasonable. The Washoe numbers are odd -- Obama up by 12 among likely and 18 (!) among registered voters there. More in Washoe than


shopping at this store ever since we became dog owners. I had been curious to visit even before we got our dog, however after our vet recommended visiting, I couldn’t resist. The moment I walked in the store, I was in heaven! All of the dog and cat treats, toys, food and more that you could ever imagine!! Beyond all of the amazing, high quality items is the customer service that is provided by the helpful store employees. Each time we visit, we are warmly greeted and provided with any assistance we need. I love the fact that dogs are welcome to visit the store. Our dog always looks forward to visiting and tasting the treats available for sampling. Another thing I absolutely love is that they workthey have cute cats roaming the aisles. There’s even a nice little sitting area with a TV and Keurig and pet friendly. I’d much rather give this local business my money! –Alycia, P – June 1, 2015 (Yelp)

I love the products here and the staff is so friendly and very knowledgeable in their products. I have a few special needs animals (high energy Australian cattle dog/American Staffordshire terrier mix and a diabetic cat) and they are great with helping me find the right food and great toys to keep my crazy dog busy. Things can be pricey but I look at it the same way as I do with our food – you have to pay more for better quality. I also love their flea and tick products!


User targets as static binariesEnables both 'static-softmmu' and 'static-user'Enable support for snappy compressionEnable SystemTAP/DTrace tracingEnable the TCG Interpreter which can speed up or slowdown workloads depending on the host and guest CPUs being emulated. In the future it will be a runtime option but for now its compile time.Enable TLS support for the VNC console server.
For 1.4 and newer this also enables WebSocket support.
For 2.0 through 2.3 also enables disk quorum support.Enable jpeg image support for the VNC console serverEnable png image support for the VNC console serverEnable USB passthrough via dev-libs/libusbUse sys-apps/usbredir to redirect USB devices to another machine over TCPEnable UUID support in the vdi block driverEnable VDE-based networkingEnable accelerated networking using vhost-net, see http://www.linux-kvm.org/page/VhostNetEnable VirtFS via virtio-9p-pci / fsdev. See http://wiki.qemu.org/Documentation/9psetupEnable terminal support (x11-libs/vte) inpackage(default_visibility = ["//visibility:public"])

load(
    "@io_bazel_rules_go//go:def.bzl",
    "go_library",
    "go_test",
)

go_library(
    name = "go_default_library",
    srcs = ["uploadconfig.go"],
    importpath = "k8s.io/kubernetes/cmd/kubeadm/app/phases/uploadconfig",
    deps = [
        "//cmd/kubeadm/app/apis/kubeadm:go_default_library",
        "//cmd/kubeadm/app/apis/kubeadm/v1alpha1:go_default_library",
        "//cmd/kubeadm/app/constants:go_default_library",
        "//cmd/kubeadm/app/util/apiclient:go_default_library",
        "//pkg/api/legacyscheme:go_default_library",
        "//vendor/github.com/ghodss/yaml:go_default_library",
        "//vendor/k8s.io/api/core/v1:go_default_library",
        "//vendor/k8s.io/apimachinery/pkg/apis/meta/v1:go_default_library",
        "//vendor/k8s.io/client-go/kubernetes:go_default_library",
    ],
)

filegroup(
    name = "package-srcs",
    srcs = glob(["**"]),


Movie:

Animal rights activists break into an animal research centre with the aim to release lab animals from their tormentors. During the raid, the activists are warned by a lab technician not to release the apes which are infected with 'rage'. They don't listen and suffer a frenzied attack from the freshly liberated primates. Fade to black...

Jim wakes up in hospital 28 Days Later. After detatching himself from the equipment he's hooked up to, and grabbing a doctor's gown to hide his modesty, he stumbles through the deserted building, puzzled and concerned that not a single person is around. As he leaves the hospital and wanders the eerily empty streets of London he begins to realise that all is not as it should be.

Jim meets up with Selina andMajor Henry West and his men. The stately home they have taken over is strongly protected and they have food and hot running water. They even have a member of their squad infected with rage, chained up in the yard, to try to find a way round the disease.

Just as the survivors think they are safe, they begin to realise that the Major does not have their safety as his prime concern. Now they have to battle, not only a psychotically infected poulation, but also an armed and extremely dangerous army unit for survival.

Review:

I don't know if it's just because I'm a Brit, but this movie just seemed so real. Everything is familiar in a way that it isn't with the Hollywood productions. This makes for a movie


but as a workaround you can add an explicit coordinate relative to (r) to use instead:
\documentclass{standalone}
\usepackage{tikz}
\usepackage{tikz-qtree}
\usetikzlibrary{backgrounds, fit, shapes,calc}

\begin{document}
\begin{tikzpicture}[level distance = 25pt, sibling distance = 15pt,   edge from parent/.style= {
      draw, edge from parent path = {(\tikzparentnode) -- (\tikzchildnode)}}]   \tikzset{every tree node/.style = {align = center, circle, draw, fill = red!40},
      leaf/.style = {fill = teal!40}}

      \Tree [.\node[](c){$c$};
              [.\node[](l){$l$};
                [.\node[leaf](l1){$l_1$}; ]
                [.\node[leaf](l2){$l_2$}; ]
  ]
      ]
      \coordinate (rr) at ($(r)-(0,.6)$);
      \node () [draw, dashed, cyan, rounded corners, fit = (l) (l1) (l2)] {};
      \node () [draw, dashed, cyan, rounded corners, fit =  (rr) (rl) (l3) (l4) (l5) ] {};
\end{tikzpicture}
\end{document}

A:

You just need to name the node something other than r. Below, I use 3r for no particular reason.
\documentclass[border=10pt]{standalone}
\usepackage{tikz}
\usepackage{tikz-qtree}
\usetikzlibrary{backgrounds, fit, shapes}

\begin{document}
\begin{tikzpicture}[level distance = 25pt, sibling distance = 15pt,   edge from parent/.style= {
    draw, edge from parent path = {(\tikzparentnode) -- (\tikzchildnode)}}]   \tikzset{every tree node/.style = {align = center, circle, draw,


CNE-2 cell ([Figure 2E](#fig2){ref-type="fig"}). We further examined the expression of key viral genes and proteins, such as *EBNA1* (a gene marker for the latency), *BALF5* (a gene expressing DNA polymerase, a lytic protein) and viral transcriptional regulatory gene *BZLF1* (an indicator for lysis induction) of EBV^[@bib51]^, in the sorted CNE-2 cells. As revealed by RT-PCR ([Figure 2F](#fig2){ref-type="fig"}) and western blotting assays ([Supplementary information, Figure S2B](#sup1){ref-type="supplementary-material"}), *EBNA1*, *BALF5* and *BZLF1* mRNAs were expressed in the sorted CNE-2 cells with the similar patterns to those of GFP-Akata cells, but not detected in original CNE-2 cells. The accumulation of EBV virions in CNE-2 cells was also detected by TEM ([Figure 2G](#fig2){ref-type="fig"}). EBV-like virions were readily observed in the cytoplasm of CNE-2 cells with cell-in-cell structures. The size of the virions wasright, blue line for A-EBV infection). Surprisingly, based on the expression of GFP fluorescence, we found that C-EBV from iCNE-2 cells infected both AK31 ([Figure 3A](#fig3){ref-type="fig"}, left, red line, 10.1%) and CNE-2 cells ([Figure 3A](#fig3){ref-type="fig"}, right, red line, 14.8%). It is well established that deficiency of EBV receptor such as CD21 molecules on ECs is the main obstacle for their susceptibility to cell-free EBV infection^[@bib19]^. However, the extra ability of C-EBV to infect CNE-2 cells suggests that CNE-2 cells infected via in-cell infection are able to assemble virions with an extra capacity to infect non-susceptible ECs. This was confirmed when we further compared the capacity of A-EBV and C-EBV to infect other lymphocytes or EC-derived cell lines ([Figure 3B](#fig3){ref-type="fig"}). While A-EBV only infected B cell line AK31, C-EBV


[Figure 3C](#fig3){ref-type="fig"}, A-EBV only infected AK31 cells with the infection rate of 10%-15%, and the unbound A-EBV collected from the AK31 absorption assay showed decreased infection rate for AK31 cells (1%-5%). A-EBV did not infect CNE-2 cells. No GFP^+^ CNE-2 cells were detected after the incubation with A-EBV. Unbound A-EBV from the CNE-2 cell absorption assay could continue to infect AK31 cells with an infection rate (8%-12%) comparable to that of original A-EBV (10%-15%; [Figure 3C](#fig3){ref-type="fig"}). On the other hand, C-EBV retained the ability to infect AK31 cells and gained an extra ability to infect CNE-2 cells ([Figure 3D](#fig3){ref-type="fig"}). C-EBV infected AK31 with the infection rate of 12%-15%, which was comparable to that of A-EBV (10%-15%). In addition, C-EBV infected CNE-2 cells with 5%-10% infection rate, much higherCNE-2 cells during the same observation time ([Supplementary information, Figure S4](#sup1){ref-type="supplementary-material"}). Our results were in accordance with the report^[@bib55]^ that EBV immediate-early protein BRLF1 could induce the activation of PI3K/AKT and the subsequent viral activation. This suggests the involvement of the PI3K/AKT signaling in EBV activation within GFP-Akata cells during in-cell infection. When the co-culture continued, the level of phosphorylated AKT increased in GFP^+^ GFP-Akata cells inside CNE-2 cells ([Figure 5B](#fig5){ref-type="fig"}). To further demonstrate the role of the PI3K/AKT signaling in EBV activation, the broad-spectrum PI3K signaling inhibitor, Wortmannin, was added after GFP-Akata cells were co-cultured with CNE-2 cells for 2 or 4 h. After another 24 h co-culture, GFP signal and AKT phosphorylation were measured in cell-in-cell structures. As shown in [Figure 5C](#fig5){ref-type="fig"}, Wortmannin dramatically inhibited the


constitute two prerequisites for the efficient transmission of EBV from internalized GFP-Akata cells to CNE-2 cells. The significance of ligation-independent EBV activation is that the latency of EBV can be rapidly interrupted when EBV-burdened B cells are internalized into ECs. This process might be related to the intrinsic maintenance of long-term persistent infection.

More importantly, our results revealed that in-cell infection altered the tropism of virions. EBV generated from in-cell infected CNE-2 cells exhibited high potency to infect both B cells and ECs in cell-free conditions. It is reported that EBV infection of ECs is supposed to allow the virus to gain optimal tropism^[@bib56]^ and the rapid expansion of infection^[@bib33]^. During in-cell infection, EBV is activated in tropic B cells and released to ECs after entotic death of Bobjective. To confirm whether GFP-Akata cells were completely internalized by CNE-2 or NEPC1-Bmi1 cells, cells were imaged by using a confocal laser scanning microscope (Carl Zeiss Inc) with a 63× objective. Volocity software was used for image acquisition. 4, 6-diamidino-2-phenylindole (DAPI; Invitrogen) was added before the observation to localize the nucleus.

In-cell EBV infection
---------------------

EBV-negative CNE-2 or NEPC1-Bmi1 cells (4 × 10^4^) were co-cultured with GFP-Akata cells (4 × 10^5^) in 24-well plates with sterile, acid-treated 12-mm coverslips inside. Coverslips were collected every 2 h and cells were fixed with 4% PFA. GFP-positive CNE-2 cells were counted on a Leica AF7000 fluorescence microscope using a 63× 1.3 numerical aperture PlanApo objective. In some experiments, DMSO (Sigma-Aldrich) or Wortmannin (Sigma-Aldrich) was added into the culture medium at the concentration of 1.0


4 °C for 2 h and post fixed in 0.1% PBS with 1% osmiumtetroxide. After dehydration through gradient ethanol solutions, the specimens were embedded in Araldite-Epon (Embed-812, Electron Microscopy Sciences, USA). Ultrathin sections were prepared with an ultramicrotome (Leica, Germany). Pale-gold sections were collected on 200-mesh copper grids. Ultrathin sections were stained with uranyl acetate and lead citrate (Electron Microscopy Sciences) and examined with transmission electron microscope (Hitachi, JP).

*In situ* hybridization (ISH)
-----------------------------

ISH was performed to investigate *EBER* expression. The Alexa Fluor 568-conjugated *EBER* probe was designed and synthesized by Da\'an Company (China). The in-cell infected CNE-2 cells were seeded on sterile, acid-treated 12-mm coverslips in 24-well plates (Corning) overnight. The coverslips were air dried and fixed with freshly prepared 0.1 M phosphate buffer (pH 7.4) containing 4% PFAListen to Awaken Your English - Corso d'inglese per italiani

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If this is the first time e-mailing your Kindle, you need to find or set the Kindle e-mail address (something like yourname@kindle.com) and add your existing support@scribl.com e-mail address to the list of sender e-mail addresses your device will accept.

To the right of the "Manage Your Content and Devices" heading, select "Preferences".

Scroll down to the heading "Personal Document Settings" (about half way down the page)

NOTE: If you are using a device other than a Kindle, and you don't see your device listed, it is probably not supported. In this case, we recommend using a standard EPUB reader for your


device, like the built-in iBooks on iOS devices or Edge browser and ebook reader on any Windows 10 device.

Note the e-mail address associated with the device you want to use. This is the address you must enter on Scribl as your "Kindle e-mail address."Bailments sec. 25, at 384 (1962), as follows: "A bailor has the duty to use ordinary, due or reasonable care to furnish chattels which are reasonably fit for the purposes of the bailment, or capable of the use, known or intended, for which they are bailed... . To this end the bailor must use reasonable care to inspect or examine the chattel before delivering it to the bailee, particularly where it was made by a third person. Under other authorities, the bailor owes a duty to the bailee and to third persons to make the chattel safe for the use to which it is to be put, or to give warnings of the danger of which he knows, and to make any reasonable inspection of the chattel to


question there was a dispute in the testimony, and all doubts or conflicts in the evidence have been resolved in favor of the plaintiff, and on this point we see no reason to disturb the verdict of the jury." There being evidence that the inspection relied upon by Compress was not reasonable, I am of the opinion the court below did not err in overruling the motion of Compress for a peremptory instruction.
The case should be reversed and rendered as to Brent and reversed and remanded for a new trial as to Compress.
ETHRIDGE, J. joins in this dissent.
testing). Results for the dynamometer were also almost exactly at chance. Testing whether there was a significant difference in proportions for whom the AK test worked, based on a belief about whether it would work, resulted in non-significant chi-square values of 0.6 (p = 0.44) for the trials with one kinesiologist, and 2.222 (p = 0.14) for the hand dynamometer trials. The final variable examined was gender. While there was no significant difference in performance for males or the hand dynamometer, the combined data for the two female kinesiologists did reveal a difference. Of the 33 sessions with females, only 15 were successful (45%) while for the 18 sessions with males, 14 were successful (78%) resulting in a chi-square statistic of 4.96, p = 0.026.

Conclusion
==========

Study and review of


with his staying power.

Some critics initially said he lacked vision. He earned the nickname “urban mechanic” for what seemed to be a small-bore focus on things like fixing streets or adding bike lanes. Amid a construction boom, Menino never met a ribbon cutting he didn’t like.

But to him, little efforts were part of something big.

"What is a vision?" Menino asked in a 1994 Boston Globe profile. "Sometimes we get caught up in the grandiose. My vision is jobs, a better school system, community policing, health care. When I leave this job, I want the city to be in better shape than when I took it over."

The work remains unfinished – perhaps why Menino pondered the idea of seeking a sixth term.

Whoever succeeds him will have more work toand has its intersection point at the center of the insulating material sheet and their four edges reach to the four edges of the insulating material, and the second lead internal conductor is formed like a linear shape with a predetermined width and placed so that one end thereof is connected to the first lead internal conductor nearly at the center of the insulating material sheet and the other end thereof is connected to a predetermined spot of the end of the coil.
According to this multi-laminated inductor, the coil and the external terminal electrode are electrically connected by means of the first and second lead internal conductors. Since these first and second lead conductors are formed like a cross and linear shape respectively, the area intersecting the magnetic


increased translation of the GCN4 mRNA, triggered by yeast\'s only eIF2α kinase, Gcn2p, which is activated by amino acid deprivation ([@bib15]; [@bib5]). Several short upstream ORFs (uORFs) mediate translational control of the GCN4 mRNA by repressing basal Gcn4p synthesis. However, under stress conditions that promote eIF2α phosphorylation and limit availability of eIF2-GTP-tRNA~i~ ^met^ ternary complexes, these uORFs favor translation reinitiation at the Gcn4p coding region and synthesis of the effector transcription factor, which binds and activates numerous genes ([@bib14]; [@bib16]).

Vertebrates have four different eIF2α kinases and these activate numerous genes in an integrated stress response (ISR), promoting cell survival and stress resistance ([@bib10], [@bib13]; [@bib25]; [@bib24]; [@bib19]). Activating transcription factor 4 (ATF4) is a transcription factor that activates many ISR target genes ([@bib13]). It too is translationally activatedthat causes ER stress and activates endogenous PERK ([@bib9]), increased ATF4-GFP translation, detected by brief pulse labeling with ^35^S-radiolabeled met/cys followed by immunoprecipitation with an anti-GFP antiserum. This mirrored changes in endogenous ATF4, detected by immunoprecipitation from the same lysates ([Fig. 2](#fig2){ref-type="fig"} B). Similar concordance between ATF4 and the reporter was observed in cells exposed to other ISR inducers ([Fig. 2](#fig2){ref-type="fig"} C). In contrast, a reporter lacking the ATF4 5′ region was repressed by thapsigargin treatment. Translational induction was eIF2α(P) dependent as it was blocked by overexpressing GADD34^C-term^, an eIF2α-directed phosphatase ([@bib23]; [Fig. 2](#fig2){ref-type="fig"} B; Fig. S1, available at <http://www.jcb.org/cgi/content/full/jcb.200408003/DC1>).

Reporter activation tapered off at highest doses of AP20187, which strongly repress global protein synthesis (reflected in reduced translation of the neomycin phosphotransferase, NPTII, marker carried on the same


the ATF4 5′ region is unable to direct efficient internal ribosome initiation. Replacement of the SV40 termination and mRNA processing signals of the reporter gene with the endogenous ATF4 mouse genomic fragment did not affect the reporter ([Fig. 3](#fig3){ref-type="fig"} C), suggesting that communication between the 5′ and 3′ ends of the mRNA are unimportant to its translational regulation.

![**ATF4 mRNA translation requires ribosomes scanning.** (A) Predicted structure of the mRNA expressed by the reporter genes. Depicted is the stem loop introduced at the 5′ end of the mRNA and replacement of vector derived viral termination and poly-adenylation sequences (thin line) with *ATF4* derived termination sequences (white rectangle). (B) Autoradiogram of SDS-PAGE of radiolabeled proteins from untreated and AP20187-treated CHO cells expressing Fv2E-PERK. The cells were transfected with ATF4-GFP reporterscells. Pulse labeling and immunoprecipitation showed high levels of translation initiation at both uORF1 and uORF2 under basal conditions ([Fig. 4](#fig4){ref-type="fig"}). Translation initiation at these uORFs was 10--20-fold higher than at ATF4. But unlike ATF4, which is translationally induced by eIF2α(P), both uORF1 and uORF2 were repressed by these conditions.

![**Both ATF4 uORFs are translated under basal conditions.** (A) Predicted structure of the mRNA expressed by the reporter genes used in these experiments. (B) Autoradiograms of SDS-PAGE of radiolabeled proteins from untreated and AP20187-treated Fv2E-PERK^(+)^ CHO cells transfected with the ATF4-GFP reporter, or reporters fusing uORF1 or uORF2 to GFP. Cytoplasmic RNA from a parallel sample of untreated, transfected cells was resolved by Northern blot and hybridized to GFP and GAPDH probes. The low basal expression of NPTII in


now fully modernised, in keeping with most of the accommodation and bars on campus.

Gallery

Sport
Bowland College regularly competes in weekly inter-collegiate sports against the other 8 colleges of Lancaster University. This comes in the form of their 4 men's football teams, 4 lady's netball teams and various bar sports including table tennis, pool and darts.

Bowland College won the inter-college trophy, the Carter Shield, in 2006, 2007, 2008 and more recently in 2016. It is also the overall winner of the Founders Trophy, an annual competition between Bowland and Lonsdale, the two founding colleges of Lancaster University. The competition usually takes place during the final term of the academic year, over a four day period. The two colleges compete in various sports including conventional college sports and also sports notQ:

How to get html from partial view from within controller

I have an e-commerce type application and when the user submits their payment I want to display a receipt page as well as a copy of the receipt in an email.  Since the HTML for the receipt page and the receipt email is the same I would like use the View to generate HTML for the email.
How can I get the html from a view from within the controller?

A:

You may take a look at the following article. But because you mentioned emailing views you should definitely take a look at MvcMailer. Scott Hanselman also blogged about it.


error in their calculation and provided a correction, see [@MR1275740]. Here we define a natural inclusion matrix corresponding to orthogonal arrays and signed orthogonal arrays. We compute the rank of this matrix and study bases of its null space. This provides helpful insight for studying these objects. In the special case of Latin squares we show that there is a straightforward algorithm for generating a basis for this matrix using the so-called intercalates. We also extend this idea for more general cases.

We follow the notations of [@MR924450] as much as possible. Let $V := \{0, 1, \ldots, v-1\}$ and $V^k$ be the set of all ordered $k$-tuples of the elements of $V$, i.e., $V^k := \{(x_1,
\ldots, x_k) \mid x_i\in V, i=1, \ldots, k\}$. Also, let $V_I^t
:=\{(u_1,\ldots,u_t)_I\mid u_i\in V, i=1,the volume is the number of nonempty cells. For each row $r$, $0\leq r\leq v-1$, we let ${\cal R}_P^r$ denote the set of entries occurring in row $r$ of $P$. Formally, ${\cal R}_P^r=\{P_{rj}\mid P_{rj}\in V \wedge (r,j;P_{rj})\in
P\}$. Similarly, for each column $c$, $0\leq c\leq v-1$, we define ${\cal C}_P^c=\{P_{ic}\mid P_{ic}\in V \wedge
(i,c;P_{ic})\in P\}$.

A [Latin trade]{}, $T=(P,Q)$, of [volume]{} $s$ is an ordered set of two s, of order $v$, such that

1.  ${\cal S}_P={\cal S}_Q,$

2.  for each $(i,j)\in {\cal S}_P$, $P_{ij}\neq Q_{ij},$

3.  for each $r$, $0\leq r\leq v-1$, ${\cal R}_P^r={\cal R}_Q^r,$ and

4.  for each $c$, $0\leq c\leq v-1$, ${\cal C}_P^c={\cal C}_Q^c$.

Thus a Latin trade is a pair of disjoint s of the same shape and order, which are row-wise and column-wise mutually balanced. We refer


to the shape of a Latin trade $T$ as the shape of the individual components $P$ and $Q$.

\[ex:main\] Below is an example of two partial Latin squares which together form a Latin trade of order 5 and of volume 19. To conserve space we will display a Latin trade by superimposing one partial Latin square on top of the other, and using subscripts to differentiate the entries of the second from those of the first, as shown below.

\[fig:latin trade\]

   .   .   2   3   1
  --- --- --- --- ---
   .   2   .   1   4
   1   .   0   4 + p.pursuerPosition.x.ToString () + "," + p.pursuerPosition.y.ToString () + "," + p.pursuerPosition.z.ToString () + Environment.NewLine;

            }
            checkpointToText += "%" + Environment.NewLine;
            #if !UNITY_WEBPLAYER

            System.IO.File.WriteAllText (fileName, checkpointToText);

            #endif
            Debug.Log("Finished writing text to file");
}

Now for some reason that last debug doesn't always get printed and my file is not always written. What could be causing this?

A:

The issue is that your collection checkpoint.storedStats is being


The 12-month effects of early motivational interviewing after acute stroke: a randomized controlled trial.
The purpose of this study was to determine whether motivational interviewing (MI), a patient-centered counseling technique, can benefit patients' mood and mortality poststroke. This was a single-center, open, randomized, controlled trial. The setting was a hospital with a stroke unit. Four hundred eleven consecutive patients on the stroke register were >18 years old, not known to be moving out-of-area postdischarge, not receiving psychiatric or clinical psychology intervention, and were without severe cognitive or communication problems preventing participation in interviews. All patients received usual stroke care. Patients in the intervention group also received 4 individual, weekly sessions of MI. The primary outcome was the proportion of patients with normal mood measured by the 28-item General HealthQuestionnaire (normal <5; low ≥5) using a mailed questionnaire at 12 months poststroke. At 12-month follow-up (including imputed data), 37.7% patients in the control group and 48.0% patients in the intervention group had normal mood. Twenty-five (12.8%) of 195 patients in the control group and 13 (6.5%) of 199 patients in the intervention group had died. A significant benefit of motivational interviewing over usual stroke care was found for mood (P=0.020; OR, 1.66; 95% CI, 1.08 to 2.55) and mortality (P=0.035; OR, 2.14; 95% CI, 1.06 to 4.38). Results suggest that motivational interviewing improves patients' mood and reduces mortality 12 months poststroke. URL: www.controlled-trials.com. Unique identifier: ISRCTN54465472.


                                        5
duty on the part of a federal agency.” 28 U.S.C. § 2680(a). The District Court dismissed

Appellant’s claims after concluding that the government was immune from liability for

the conduct alleged. Appellant’s brief contains but one page challenging the District

Court’s conclusion on this crucial issue.

       The purpose of discretionary immunity is to “prevent judicial ‘second guessing’ of

legislative and administrative decisions grounded in social, economic, and political policy

through the medium of an action in tort.” United States v. Gaubert, 499 U.S. 315, 323

(1991). Appellant raisedthree general theories of negligence in its claim against the

United States; negligent design of the NPCDF, negligent violation of regulations in

design, and negligent maintenance of the NPCDF. In determining whether the Corps of

Engineers’ actions in building, operating, and maintaining the NPCDF were protected as

discretionary functions, the District Court correctly noted that, where a government

policy established “by statute, regulation, or agency guidelines, allows a Government

agent to exercise discretion, it must be presumed that the agent’s acts are grounded in

policy when exercising that discretion.” Gaubert, 499 U.S. at 324.

       The District Court correctly concluded that Congress conferred discretion on the

Corps of Engineers to maintain navigable waterways, and specifically the discretion to

plan for and conduct dredging operations. E.g. 33 U.S.C. § 622 (“The Secretary of


OCZ VECTOR 180 The Vector 180 is the successor to the Vector 150 that OCZ released in 2013. The Vector line of SSDs is designed for the enthusiasts as it often carries higher endurance rating and warranty. The original Vector 150 paired OCZ’s own in-house Indilinx Barefoot 3 M00 controller with Toshiba ...

Crucial BX100 Crucial MX100 was one of the best affordable SSDs on the market last year. This year, Crucial updated the line-up with not one but two drives: the BX100 and the MX200. While the MX200 is the successor to the MX100 and aimed for mainstream market, the BX100 is designed ...

SilverStone Fortress FT05 (Silver W/ Window) The Revolutionary SilverStone FT05 is the fifth generation Fortress computer chassis SilverStone has offered. This one offers the samepassengers around the country are becoming comfortable with the idea of hailing a ride via mobile app, and the designation between a commercially licensed driver and one who isn’t licensed doesn’t matter quite so much to most.

That is to say, the same education Lyft needed to provide to users two years ago isn’t quite as necessary in today’s environment. In the same way, it no longer needs a big pink mustache on the grill of its cars to make users aware of its service.

And, finally, more education and awareness among consumers about available ride-sharing services means there’s less actual differentiation between them. Increasingly, users aren’t choosing a Lyft or an Uber based on friendliness of feature set, but based on price and availability.

He who isn’t surge pricing and


Elsa Marston

Elsa Harik (née Marston), (March 18, 1933 – February 16, 2017) known professionally as Elsa Marston, is an American author of children's books about the Middle East and North Africa. She died after completing her last book, "I Just Kept Walking."

References

Category:1933 births
Category:2017 deaths
Category:20th-century American women writers
Category:20th-century American writers
Category:American children's writersstraight in at number one on the other side of the charts this week, knocking Rihanna’s fifth effort ‘Loud‘ into second place, after dominating the UK charts in recent weeks.

Another new entry in the album charts comes from rock band White Lies with their second album ‘Ritual’, which charted at number three, following on from their impressive debut album which hit the number one spot. Adele’s debut album ‘19‘ also re-appears in the top ten this week at number eight, ahead of the release of her new album ‘21‘ out tomorrow.

Though I’m not a huge fan of Bruno Mars, it would be hard to dismiss his talent and deny that he has been extremely successful in his career so far, and I think he will go on to


disguised in his Obama mask, has been carrying out similar raids for the last two years.

I love it when people rob banks in masks of famous people. It just makes me laugh.

In late 2010, I decided to invite all members of Habbox Forum to take part in a huge survey; that would determine what Habbox’s favourite songs of the 2000-2009 decade are. After two months that consisted of you nominating your favourite songs, me compiling the list, and you voting for your favourite songs from that very list – the top ten favourite songs have been chosen. These songs will be revealed in a three part series this week right here on Habbox. So, without further ado, here is the first part of the best songs of thedriving taxicabs all day and living in a ****** apartment and ‘appearing’ really threatening to society. But not being so. Because, by the time you’ve finished working a 20-hour shift, you’re so tired you [just] want to get home to the family,” she explained.

The song is truly a highlight from ‘Kala’, and is one of my personal favourites from this list!

That’s all for part one! Share your views in the comments as well – who will be number one on our list? Keep posted here for the next instalment later this week!

Do you like playing Pokemon? Well if you do, you’ll be glad to hear that nitendo have created new editions to the Pokemon games saga(Black & White).

There are 156 brand new Pokemon available on both games, there


to all the hype, and now I can’t wait even more!

Habbox is not affiliated with, endorsed, sponsored, or specifically approved by Sulake Corporation Oy or its Affiliates. Habbox may use the trademarks and other intellectual property of Habbo, which is permitted under Habbo Fan Site Policy.great step. Other cities have already started to cite Chandigarh as an example and a role model city. If we talk about greenery it is important to mention that Chandigarh ranks number there as well. Almost 37% of the city area is under green cover. And this is the reason Chandigarh is also being called as the city of Gardens.

Come, lets join hands to keep our city clean so that we are able to maintain the “Cleanest City of India” tag for the year 2015 as well.

Comments

Ajay Deep is a young enthusiast who Loves Chandigarh and is always eager to make this beautiful city even more beautiful. A Mechanical Engineer By Chance and Working in an IT MNC by Choice. A Writer, Photographer and a Budding Entrepreneur. A


day job.

Tomàs laughed. "You know the people, but I wouldn't believe the shit they tell you. Anyway, no-one needs a pill to get it up when the women here are so hot."

Joan slurred something from which only "hot" and "your sister" were intelligible. Tomàs cuffed him on the back of the head.

"Bring her up again, friend, and …" They both knew threat was empty. As Tomàs' cousin, Joan's drunken cracks about Tomàs' sister were a well-worn part of their friendship.

Joan wandered off to take a piss, and Xavi to get the next round of drinks. Now was Tomàs' opportunity. He leaned closer to avoid shouting over the pounding music.

"Raf, do you know if there is a local supplier for ketamine, midazolam, that sort of thing?"

Rafael's eyes widened slightly.an extra shadow. Hanging from a lamppost, swinging in a slight circle, was a human leg, a rope slung around the ankle. Blood had trickled from the thick stump of the thigh, adding a further dark stain in the circle of lamplight.

"Deu meu!" Xavi had stopped dead, looking up.

Tomàs, in contrast, was looking ahead to the shape dangling beneath the next lamp. And the next. And the next.

From the third hung a head, with a neck and one torn off shoulder. Flesh hung in glistening ribbons; stark bone protruded. The face was staring, a single grey feather - perhaps a pigeon's - jammed into each eye.

Xavi was first to speak. "Jesus Christ. That's Raf."

It was: their friend had been ripped apart and pieces hung from every lamppost on


Malocclusion: esthetic impact and quality of life among Brazilian schoolchildren.
The objectives of this study were to assess the esthetic impact of malocclusion on the daily life of Brazilian schoolchildren and to test the association between esthetic impact due to malocclusion and biopsychosocial variables. The sample comprised 333 randomly selected subjects aged 10 to 14 years. The oral impact on daily performance (OIDP) instrument was used to assess the esthetic impact, and the dental aesthetic index (DAI) was used for clinical assessment. The subjects were further evaluated as to their self-esteem (global self-evaluation) and self-perception of oral esthetics (oral aesthetic subjective impact scale). Other variables were assessed through questionnaires. Multiple logistic regression was used in the data analysis. Twenty-seven percent of the children reported an esthetic impact on theirduring the fourth quarter of the year 2016 for both the non-separated (Fig. [3a,b](#Fig3){ref-type="fig"}) and the separated (Fig. [3c,d](#Fig3){ref-type="fig"}) datasets. We can observe that the patterns of parking density better match with the non-separated travel time data for both weekdays and weekends (Fig. [3a,b](#Fig3){ref-type="fig"}) than with the separated ones (Fig. [3c,d](#Fig3){ref-type="fig"}). In these, both the sampled (red) and measured (blue) parking densities rise, reach their peaks and decline at the same time. With the datasets that are separated by day types (Fig. [3c,d](#Fig3){ref-type="fig"}), our modeled (red) rise, peak and decline phases of parking density mismatch with the measured (blue) values.Fig. 3The measured (blue) and sampled (red) parking densities for different datasets of Melbourne in the exemplar city zone 956 in the fourth quarter of the year 2016. (**a)** Weekdays with travel time data


latitudinal position: the distance between two longitudinal lines is around 111.3 km at the equator and 0 at the north and south poles. The dependence on the latitudinal position *lat* can then be expressed as 111.3 km ⋅ cos(lat). If we replace the average distance of 71.5 km per longitudinal degree with this expression within the Pythagorean theorem, we can calculate the distance *d*~*ij*~ between two zones i and j at the points (*long*~*i*~\|*lat*~*i*~) and (*long*~*j*~\|*lat*~*j*~) as:$$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
        \begin{document}$$P({X}_{t+1}| {X}_{t})=P({X}_{t+1}-{X}_{t})=P({\varepsilon }_{t})$$\end{document}$$

The problem that we want to solve can be formulated as finding the car flow probabilities $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}


               \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$$P(C=0)=P(A=0)=(1-{p}_{i,t}^{drive})\cdot {\underbrace{\mathop{\sum }\limits_{j=1}^{N}{p}_{ij,t}^{dest}}}_{=1(normalized)}=(1-{p}_{i,t}^{drive})\quad (Marginalization)$$\end{document}$$$$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
            can for instance be carbon emissions, fuel consumption and transported amount of people for each trip. We introduce for all v = 1...V, i, j = 1...N and t = 1...T:$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}


of trips are sampled by generating random variables from the truncated Gaussian distributions in (20) and (21) for each trip.

Model selection for *e*~*drive*~ and *e*~*dest*~ {#Sec17}
------------------------------------------------

The parameters *e*~*drive*~ and *e*~*dest*~ determine the functional relationship between travel time data and the joint Origin-Destination probabilities of the modeled traffic system. In order to find a good choice for them, we must evaluate the values of interests in our model with real world observations. The values that we are mainly interested in in this modeling task are the circadian rhythm of traffic activity and the spatio-temporal distribution of car parking densities. We hence use measurements of these two values to make a good choice for *e*~*drive*~ and *e*~*dest*~. The subsequent subsections describe how the validation works in detail. In this subsection             \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$${e}_{b}^{(n)}$$\end{document}$ with the best found evaluation error $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
                \usepackage{amssymb}


selection for *p*~*min*~ and *p*~*max*~ {#Sec18}
---------------------------------------------

The parameters *p*~*min*~ and *p*~*max*~ determine the range of probabilities for deciding whether a car drives or parks given the time of day and zone of presence; they were initially set to arbitrary values that satisfy the conditions in (8) and (9). Once we have first sampling results, we can use *p*~*min*~ and *p*~*max*~ to normalize our traffic system according to one or more set point values. We defined the two state transition properties travel duration and travel distance which we can use both for normalization. Here, we use the share of driving time within the lifetime of a vehicle for normalization and introduce:*A*~*set*~: = the realistic amount of driving time*A*~*drive*~: = the sampled amount of driving time

If we assume that the realisticsensed street segments during time step t

Validation metric {#Sec21}
-----------------

We validate our model by calculating the Mean Squared Error between sampled and measured traffic activities and parking densities. We scale all sampled and measured values with respect to their minimum and maximum values among all time steps t = 1...T in order to be able to make sensible comparisons. For all validatable zones *m* ∈ *M* and t = 1...T, we calculate the sampled parking densities $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}


during which it will not fire ([Methods](#Sec8){ref-type="sec"}), thereby defining a maximum firing rate. Within the Fire-Diffuse-Fire framework, the refractory period is chosen somewhat ad hoc, often to match experimental values \[[@CR46]\] or to investigate hypothetical scenarios. Here we investigate the impact of coupling oscillations on either side of the NE that may have different frequencies. Therefore we have chosen refractory periods that depend primarily on the properties of the compartment and not on their coupling: the compartments with lower *D* have a larger refractory period ([Methods](#Sec8){ref-type="sec"}). Under these conditions, Fig. [4](#Fig4){ref-type="fig"}[a](#Fig4){ref-type="fig"} & [b](#Fig4){ref-type="fig"} shows that an integrated perinuclear signalling machinery, composed of nuclear and cytosolic channels with independent refractory periods coupled by a transparent NE, will result in an average nuclear Ca^2+^ concentration that oscillates with an autonomousare not independent, so long as channel refractory periods in the two compartments are different. By contrast, given that the time to transmit the first Ca^2+^ wave is negligible (see Fig. [4](#Fig4){ref-type="fig"}[a](#Fig4){ref-type="fig"}1 and [b](#Fig4){ref-type="fig"}1), if the refractory period was the same on both sides of the NE then nucleosolic and cytosolic Ca^2+^ oscillations could be synchronised, as observed for instance during plant symbiosis \[[@CR20]\] (see Additional file [2](#MOESM2){ref-type="media"}). It has been argued that Ca^2+^ signatures encode information about the stimuli and determine the elicited response \[[@CR12], [@CR13], [@CR60]\]. In cases for which nuclear and cytosolic Ca^2+^ signals perform different roles, different spatiotemporal patterns in these compartments may be essential. Yet even under these circumstances, the flux of calcium through pores can play an essential role in maintaining the


\usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document} $$ \frac{d c(\mathbf{r},t)}{d t} = D\nabla^{2} c(\mathbf{r},t) - k_{\mathrm{s}} c(\mathbf{r},t) + \sum\limits_{i=1}^{N} f_{i}(t) \delta(\mathbf{r}-\mathbf{r}_{i}),  $$ \end{document}$$

where *D* is the diffusion constant and *k*~s~ is the rate at whichthe observed nuclear Ca^2+^ oscillation frequency will coincide with the individual (and independent) channels' refractory period as long as two conditions are fulfilled. First, coupling must be strong enough to allow the channels to fire at the maximum rate imposed by their refractory period. Secondly, nuclear channels should fire in unison, so their joint contribution to global Ca^2+^ levels is much larger than the pores contribution. If these conditions are met, nuclear and cytosolic Ca^2+^ will oscillate with clearly independent frequencies, see Fig. [4](#Fig4){ref-type="fig"}. For these conditions to be met, coupling strength must be strong enough: Additional file [2](#MOESM2){ref-type="media"} presents the consequences of weaker couplings.

For completeness, we have further explored some situations that promote simultaneous nuclear/cytosolic Ca^2+^ release. One way to couple and try to synchronise nuclear and


cytosolic refractory periods is to make their duration depend solely on the rate of decrease of the actual local Ca^2+^ concentration. In case pores were able to homogenise calcium concentrations on either side of the NE in between firings, the nuclear and cytosolic channels could then fire simultaneously. Otherwise, cytosolic and nucleosolic channels would still fire at different times, but their firings times would not be autonomous, see Additional file [2](#MOESM2){ref-type="media"}.

Note on parameters: When considering a realistic number of pores, the simulation of Eq. [9](#Equ9){ref-type=""} becomes very computationally expensive. One way to partially overcome this problem is to choose parameters that lead to small refractory periods, in order to investigate several calcium oscillation cycles in a shorter simulation time. The relative magnitude of the refractory period does not \fi
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If you really need this, please open a feature request at https://github.com/plk/biblatex/issues. I can't promise that this will be looked at anytime soon, but at least it will be logged then and other people and share their


+ 1. Suppose -4*y + s = 2*s + 64, -y + 2*s - 7 = 0. List the prime factors of ((-24)/y)/(c/270*-6).
2, 3
Let g be ((-35)/(1 - -4))/1. Let f = -7 - g. Suppose -4*n - 5*m = -n - 208, f = 4*n + m - 300. List the prime factors of n.
2, 19
Let t(w) = -w**3 + 14*w**2 - 3*w - 41. Suppose 4*d - 10 + 10 = 0. Suppose d = -j + 11*j - 120. List the prime factors of t(j).
211
Suppose -6*s = -12*s + 2562. Suppose -4*k + s = -345. List the prime factors of k.
193
Let h(l) = 5*l + 2. Let g be h(-3). Let k(r) = -2*r - 77. Let f(c) = 3*c + 139. Let o(i)- 13. Let a be w(-2). Let n = a + l. What are the prime factors of n?
37
Let g(n) be the first derivative of 9*n**2/2 - 20*n - 5. Let z be g(-10). Let j = z + 197. List the prime factors of j.
3, 29
Let y(v) = 3*v + 3. Let s(t) = 4*t + 2. Let l(k) = -4*s(k) + 5*y(k). Let g be l(6)


Many investors sell some of their losing stocks near year-end to book a tax loss, and that provides excellent buying opportunities for the rest of us, says MarketWatch columnist Brett Arends.

"It comes around every year, usually in late November," he writes. "Think of it as Black Friday for Wall Street's contrarians. The effect of this rushed selling is that it tends to drive down the prices of the stocks in question even further for a couple of weeks."

There should be plenty of candidates, Arends says. A whopping 139 of the companies in the S&P 500 have seen their stocks drop so far this year. That group includes minor declines, such as 0.4 percent for AT&T, and big moves, such as a 12.8 percent drop for IBM.

"The smart moveResearch Roundup

How Do Otters Remain Sleek and Warm?

Unlike many other mammals that spend a considerable amount of time in the water–polar bears, seals, dolphins, and whales–river otters do not have a thick layer of body fat to keep warm. Instead, they rely on their fur and the densely packed layer of specially adapted underhairs.

Using scanning electron microscopy and polarizing light microscopy, Dr. John W. Weisel,professor of cell and developmental biology in the School of Medicine, and colleagues, examined the structure of these hairs for clues to their exceptional insulation abilities. They found that the cuticle surface structure of the underhairs and base of the less-abundant guard hairs are distinctively shaped to interlock, with wedge-shaped fins or petals fitting into wedge-shaped grooves between fins of adjacent hairs. Dr. Weisel


and colleagues reported their findings in the Canadian Journal of Zoology.

Dr. Weisel and research specialist Chandrasekaran Nagaswami, also in the department of cell and developmental biology, usually work on defining the physical properties of blood clots and applying this knowledge to find better treatments for heart disease.

“Most hair from animals has a distinctive pattern, which is how we can distinguish one species from another,” says Dr. Weisel. The fins of one hair loosely insert into the grooves between fins of an adjacent hair, thus permitting the hairs to form a web-like pattern that keeps water from the otter’s skin and decreases heat loss. Also, the grooves between fins trap air bubbles, which help increase the thermal insulation of the otter’s coat. Indeed, biologists have observed otters actively blowingtoluenesulfonyl chemistry is somewhat limiting, given the relatively harsh conditions needed to remove this protecting group at a later stage. Screening of additional generations of these enzymes could select for those able to use the nosyl group and would result in a more user-friendly version of the reaction. In addition, the substrate scope is heavily skewed toward aromatic group-containing alkenes. It will be interesting to see how aliphatic molecules, which are often more synthetically useful than their aromatic counterparts, fare in this transformation.

![Arnold and co-workers were able to change cytochrome P450 from an epoxidation enzyme (left) to an aziridination enzyme (right) through the power of *in vitro* evolution coupled with a xenobiotic oxidant (tosyl azide).](oc-2015-001405_0003){#fig2}

In closing, synthetic chemists have long had an upper hand over nature in the


is that it was not appropriate for this tunnel. While I understand why LIRR was reluctant to have both tracks out at the same time, with proper planning this could have been built cut and cover over a week and have both tracks back on with slow speed restrictions while the concrete cures completely. I am guessing that now the plan is to take both tracks out only after ESA opens, so that the reduction in capacity to Penn is less of a problem, but I still do not see why this could not be done with a short closure.

In general, the MTA has become too concerned with complaints, both from the riding public and the politicos, to the point where necessary projects get way over budget inof these projects, you could have a structure which has reached sufficient strength to carry a train in a week, especially if the only poured in place part are the foundations.

jlr3266 wrote:I already stated that the tunnel has been pushed out on the schedule since it does not serve any function for ESA service.

Of course it does not serve any function for ESA and ESA cannot take any more delays due to incompetence and mismanagement as it is already under pressure by the Feds and the Governor to deliver, so they prefer to stick it to the current LIRR to Penn and Amtrak by not eliminating the conflicting train moves at Harold for another 5 or so years until after ESA opens. This is the typical way bureaucracy