with misdialing or transcription errors with telephone numbers. In a preferred embodiment of the subject invention, the resultant direct or indirect communications link can be used to establish both data transfer, and human real-time voice collaboration. The present invention also provides a central meeting point that clinicians may arrange to interact over at a certain time, without regard to their respective locations. Furthermore, the meeting time may be arranged by postings to the central network that may be accessed by interested or authorized parties.
In one embodiment of the present invention, a groupware system is provided allowing clinicians to make a connection to another instrument or computer for collaboration purposes, or to the network for data transmission purposes. The present invention may be implemented by, for example, supplying medicalimplemented as a software application which may be run on a server or central computer accessible via a network or direct connection by the interface medical device. In an alternate embodiment, the interface medical device may be implemented as a software client which may run on a computer remotely from the collaboration server. Preferably, the central collaboration computer, program or device is capable of autonomously and dynamically determining the model of an IMD, for example, according to manufacturer, type, and model number, as well as the specific serial number of a particular device. When an IMD is within communication range of an interface medical device, the central collaboration computer of the present invention is also preferably capable of configuring a deployed IMD, or commanding the interface medical device


first advice to Camille, find a new salon.

Second, we went for a hairstyle that was short but very much modern. Layers were the solution, giving volume where needed and Camille the added bonus of complete manageability.

I suffered from salon phobia, I did not know how to communicate with a stylist or choose the right salon. "Knowledge is Power"

Cherie was trying to "grow out" last years haircut.A battle seldom won.Here, a perfect cut, note how thewispy bangs do not add weight to the front of the style.

"How did I feel before?
Help, I need a makeover, and now? Polished, and it feels good!"

Jenny has a beautiful smile, which just needed the perfect frame, rather than holding onto length just for the sake of it.

I knew it was time for a  private int port;

    @Value("#{mongoProperties['database']}")
    private String database;

    private Mongo mongo;

    private static final Logger LOGGER = LoggerFactory.getLogger(MongoService.class);

    public MongoService() {}

    public void init() throws UnknownHostException {
        LOGGER.info("host=" + host + ", port=" + port + ", database=" + database);
        mongo = new Mongo(host, port);
    }

    public void putDocument(@Nonnull final DBObject document) {
        LOGGER.info("inserting document - " + document.toString());
        mongo.getDB(database).getCollection(getCollectionName(document)).insert(document, WriteConcern.SAFE);
    }

How can I even debug this issue?
Thanks much!

A:

There is


it takes only a few straightforward measures. Knowing maps lie helps you’ve got a better understanding of the way the world operates. There are several different maps to playwith. Maps do not have to display leadership accurately. Now you’re well prepared to love your new map! You might want to hit refresh to discover the map. Sooner or later, all channels lie, but the vast majority of folks don’t notice. It is possible to move the map wherever you want on the webpage. The Best way to produce a habit Google Map will ride your needs. You Have to put up a Google API key so as to utilize Google maps. If you only require a quick map with limited functionality you are in a position to useQ:

How do I show processes for a specific uid or username using command line in python?

for opt, arg in opts:
   if opt in ('-u'):
     arg = numuid
     ps = subprocess.Popen('ps -u ', shell=True, stdout=subprocess.PIPE)
     print ps.stdout.read()

this is what i have so far, numuid is supposed to go after ps -u and is the uid. but what do i do to have it read in whatever numuid is?

A:

You just need to pass the name as a variable, if you just want to see or store the output check_output is the simplest method:
from subprocess import check_output

out = check_output(["ps","-u", numuid])

print(out)

For python 2.6:
from subprocess import PIPE,Popen

p = Popen(["ps","-u", numuid], stdout=PIPE)
out, err= p.communicate()
print(out)

You don't need shell=True when you pass


Brain and plasma biogenic amines analysis by the EC-HPLC technique: application to fish.
A HPLC technique has been developed for the analysis of biogenic amines (noradrenaline, NA; dopamine, DA; adrenaline, A; serotonin, 5-HT) in tissues and blood and then applied to fish. It appears that when compared to classical methods, HPLC is more rapid and reliable with a lower variation in the results. This technique showed that in eel blood, 5-HT and DA (and their metabolites) are missing or at least are present at very low concentrations.'A. Laasanen'
- 'D. Lazic'
- 'L. Levchuk'
- 'L. Litov'
- 'N.K. Mondal'
- 'T. Moulik'
- 'V.S. Narasimham'
- 'A. Nemashkalo'
- 'Y. Onel'
- 'P. Petrov'
- 'Yu. Petukhov'
- 'S. Piperov'
- 'V. Popov'
- 'J. Reidy'
- 'A. Ronzhin'
- 'R. Ruchti'
- 'J.B. Singh'
- 'Q. Shen'
- 'A. Sirunyan'
- 'A. Skuja'
- 'E. Skup'
- 'P. Sorokin'
- 'K. Sudhakar'
- 'D. Summers'
- 'F. Szoncso'
- 'S.I. Tereshenko'
- 'C. Timmermans'
- 'S.C. Tonwar'
- 'L. Turchanovich'
- 'V. Tyukov'
- 'A. Volodko'
- 'A. Yukaev'
- 'A. Zaitchenko'
- 'A. Zatserklyaniy'
title: 'Studies of the Response of the Prototype CMS Hadron Calorimeter, Including Magnetic Field Effects, to Pion, Electron, and Muon Beams'
---

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 The CMS Scintillator Tile-Fiber Hadron Calorimeter
====================================================

The hadron calorimeter (HCAL) for the Compact Muon Solenoid (CMS) Detector will be used in the determination of quark, gluon, and neutrino final state momenta by measuring the energies and directions of particle jets and the missing transverse energy flow. The determination of the missing energy flow is crucial in searches for new particles and phenomena, such as possible supersymmetric partners of quarks


the edges using Bicron BC-620 white reflective paint, wrapped with white reflective $Tyvek$ [@tyvek], and sealed for light leaks with a black $Tedlar$ [@tedlar]. The WLS fibers are mirrored at one end, placed in the grooves, and epoxied in groups of ten into two optical connectors placed at the edge of each scintillator tile, as shown in Figure \[tile95\]. The stainless steel tubes are installed inside a 2 mm plastic cover and used to guide a radioactive source for calibration purposes. The entire package is held together with a set of brass rivets.

For the H2(1996) tests, a different set of scintillator tiles is used. These tiles are closer to the tower geometry of the final CMS design. Each tile is segmented into a 3$\times$3 matrix read out by nine WLS fibers insertedstrong magnetic field). The radius of curvature of a 1 MeV/c electron in a 3 Tesla magnetic field is approximately 1 mm. The size of this geometric effect is expected to be proportional to the strength of the B field and depends on the detailed structure [@abramov] and composition of the absorber/scintillator package.

A GEANT study models the calorimeter response to 10 GeV electrons as a function of the air gap between the scintillator package and the upstream absorber (see Figure \[scint\_orient\]) in the presence of a strong magnetic field. The results are summarized in Figure \[mag\_geant\_sim\]. The increase in the electron response is reduced as the distance between scintillator package and upstream absorber is increased.

The results presented so far have been taken with the scintillator package placed in the absorber gap in


as before (Eqn. 1).

Figure \[h4\_1995\_ecal\_vs\_hcal\] shows a scatter plot of the energy deposition in HCAL versus ECAL taken during the H4(1995) test beam run with pions with momenta ranging between 15 and 375 GeV/c. Unlike in the case with the Pb-scintillator ECAL, the data points are not centered on a straight line corresponding to $E_{ECAL}+E_{HCAL}$ = $p_{beam}$. The energy response of the HCAL calorimeter to “mip-in-ECAL” pions is shown in Figure \[h4\_1995\_etot\_mip\]. The response of the combined crystal ECAL+HCAL calorimeter to the “full pion sample” is shown in Figure \[h4\_1995\_etot\_all\]. The distributions for the combined crystal ECAL+HCAL system deviate from a Gaussian shape, especially at low energies.

As demonstrated earlier, the H2(1995) data with a Pb-scintillator ECAL show good linearity for the combined ECAL+HCAL calorimeter system. However, as can be seen indata is shown in Figure \[eh-cms2\].

The above results can be compared with similar analyses for other iron-scintillator sampling calorimeters. Extraction of $e/h$ for an iron-scintillator sampling calorimeter has also been done [@scifi97] by CDF. The CDF endcap hadron calorimeter consists of 22 layers of 5 cm iron absorber plates and 6 mm scintillators. The CDF results yield $e/h$ 1.34 $\pm$ 0.01 (Wigmans) and 1.42 $\pm$ 0.015 (Groom). ATLAS [@atlas_nim] measures $e/h$= 1.34 $\pm$ 0.03 assuming the Wigmans parameterization for $F({\pi^0})$. The ATLAS hadron calorimeter uses iron as an absorber with the tiles are oriented in the radial direction.

The NuTeV Collaboration reports a $e/h$ ratio for 10 cm iron sampling calorimeter [@nutev_nim] of 1.08 $\pm$ 0.01 using the Groom parameterization. Note that $e/h$ is sensitive to the sampling fraction and other geometrical effects. The CCFR/NuTeV calorimeter


uses 2.5 cm thick liquid scintillator counters, which are clad with acrylic and water bags. The cladding and the thick scintillators in CCFR/NuTeV greatly reduce the response to electrons relative to the response to pions. Also, the water and thick scintillators tend to increases the rate of conversion of low energy neutrons to protons in the active medium.

Optimization of the design of HCAL
==================================

The conceptual design of the barrel HCAL was a 5.3 $\lambda_{INT}$ thick calorimeter. The inner half of the calorimeter had 3 cm sampling (first readout segment, H1) while the second readout segment consisted of the outer half of the calorimeter with 6 cm sampling.

For the H2(1996) tests, the prototype HCAL module was segmented into 27 readout layers. Using these data we simulated various sampling configurations and studied the performancefraction of the energy deposited in the first readout segment of HCAL immediately downstream of the crystal ECAL. The dynamic weighting effectively allows one to have an energy dependent correction (for single particles) for the low response to pions which interact in ECAL.

$$E_{TOT} = (1+2\times f(H1))\times E_{ECAL} + E_{H1} + E_{H2} + E_{HO},$$

$$f(H1) = E(H1)/(E(H1)+E(H2)+E(HO)),~f(H1) \leq 0.1$$

With either the passive or dynamic weighting, the nonlinearity and resolutions for pions with energies between 30 and 300 GeV/c are improved. With the passive weighing, the fractional energy resolution of of the combined ECAL+HCAL calorimetric system can be described by the function $\sigma_{E}/E$ = 122%/$\sqrt{E}$ $\oplus$ 5%. Note that while the passive weighting can be applied to single particles and jets, the dynamic weighting may introduce high energy tails in the


film of polyvinyl fluoride polymer.

P. de Barbaro , [*Construction and Quality Control of Scintillator Tiles with WLS Fiber Readout for the 1995 CMS Test Beam Hadron Calorimeter*]{}, University of Rochester preprint UR-1430, July 1995; H. Budd, [*The CMS Central Hadron Calorimeter*]{}, , (proc. suppl.) B[**54**]{} (1997) 191.

A. Bodek and P. Auchincloss, , A[**357**]{} (1995) 292.

, pp. 367-374, CERN/LHCC 97-31, CMS TDR 2, 20-Jun-1997 and references therein, p. 389.

D. Blomker , [NIM]{}, A[**311**]{} (1992) 505.

J. Mainusch , [NIM]{}, A[**312**]{} (1992) 451.

M. Bertoldi , , A[**386**]{} (1997) 301.

V. Abramov, A [**374**]{} (1996) 34; V. Abramov, [*Instruments and Experimental Techniques*]{}, Vol. 40, [**3**]{} (1997) 318.

GEANT, Detector Description and Simulation Tool, CERN Program Library Long Writeup W5013. GEANT Version 3.21 is used with the default values for all parameters.

E. Auffray , ,A[**412**]{} (1998) 223.

R. Wigmans , , A[**259**]{} (1987) 389; R. Wigmans , , A[**265**]{} (1988) 273.

The correction for the longitudinal energy leakage for a finite length calorimeter is estimated using CCFR and NuTeV test beam measurements of hadron showers as a function of calorimeter depth. W. Sakumoto and L. de Barbaro, private communications.

W. Sakumoto , (CCFR Collaboration) , A[**294**]{} (1990) 179.

D. Harris, J. Yu, , (NuTeV Collaboration), [*Precision Calibration of the NuTeV Calorimeter*]{}, University of Rochester preprint UR-1561, , A[**447**]{} No.3, June 11, 2000. Note that CCFR and NuTeV used same iron-scintillator calorimeter.

T.A. Gabriel and D. E. Groom, , A[**338**]{} (1994) 336.

P. de Barbaro , [*Test Beam Performance of the CDF Plug Upgrade Hadron Calorimeter*]{}, Proceedings of the SCIFI97 Conference, Nov 4-11, 1997, Notre Dame, IN.

Z. Ajaltouni ,


Q:

Mantis Bugtracker: File download stops after 4Kb has been downloaded

I'm having an issue with Mantis Bugtracker (version 1.1.8), where file downloads only reach 4 Kb, and then stop. I don't know if this is a problem in the product itself, or in the PHP installation on the server. I've tried disabling output buffering (that was the only value close to 4Kb), but that didn't help.
The files are stored in the database. The application is running on IIS7 on Windows Server 2008 and Sql Server 2005, and the installed version of PHP is 5.2.11.
Does anyone have a solution that might help fix this?

A:

Okay, I think that I'm just going to have to face the fact that I'm an idiot. I had changed the textsize and textlimit properties injust a simple list.

Login screen showing entries in the Session menu.

Shutdown options from the login screen.

The default desktop. Still sporting that background.

Same desktop, different background. Go ahead, jump in!

The desktop showing the Cinnamon menu.

The desktop in Expo view. Two virtual desktops or workspaces are enabled by default.

The Software Center has shed its splash screen, and starts up slightly faster than the previous edition.

One more screen shot of the desktop showing a custom user avatar.

Installation images for Linux Mint 16 RC are available here, and a list of new features are available here.

Digital Ocean is a VPS/Cloud hosting provider. For just $5 per month, you can get yourself a Cloud server with 512 MB of RAM, 20 GB super-fast SSD, free snapshots, plus backups for a minimal fee. All


was getting ready to replace the impeller on my Fluval 405 (was making an awful noise), when I saw this (on the intake line to my Eheim 2217):

For the past 7 days or so I have been wondering what happened to 2 of the 3 baby otocinclus that I added... yes, that is one of them in the tube. He actually didn't seem too bothered. Apparently there was enough algae in that tube, plus space for him to turn around, that he quite handily moved about in the tubing.

Then, I noticed that I was missing one of my guppies... so I decided to pull the whole canister out, remove all the filter media and lo and behold, at the bottom of the canister is one of my guppieson the Nintendo Switch.

Detention

Detention is one of the most interesting horror games to come out in recent years. Set in a 1960s Taiwan that is under martial law, Detention is a 2D horror side-scroller, point and click game. Players are put in the shoes of a high schooler that must escape their high school, which has been transformed into something truly evil.

This title incorporates many East Asian elements such as Taoism, Buddhism, Chinese mythology, as well as drawing on local Taiwanese culture. Doing so allows the game to feel extremely authentic and provides a unique setting that has previously been ignored within the horror genre.

Due to the setting, the era it takes place in, and the martial law imposed throughout Taiwan, the player experience is one of obedience


we arrive at: $$\begin{aligned}
\begin{array}{lr}
\langle\hat{a}_1^{\dagger2}\hat{a}^2_1\rangle-\langle{\hat{a}^\dagger_1\hat{a}_1}\rangle^2
  =f_2^{(1)4}+2n(n-1)g_1^{(1)4}+2(n+1)(n+2)g_2^{(1)4} \\
+2n(n+1)g_1^{(1)2}g_2^{(1)2}+[f_1^{(1)}f_2^{(1)}+2(2n+1)g_1^{(1)}g_2^{(1)}]^2 \\
+4 f_2^{(1)2}[ng_1^{(1)2}+(n+1)g_2^{(1)2}]\geq 0. \label{faisal1}
\end{array}\end{aligned}$$ The final remark, the comparison between the solid curves in Figs. 2(a) and (b) shows that the nonclassical range of $r_1$ in (b) is greater than that in (a). In other words, to enhance the sub-Poissonian statistics in a certain mode, the other modes have to be prepared in states close to the classical ones.

The violation of the classical inequalities has verified the quantum theory. Among these inequalities is the Cauchy-Schwarz inequality [@lou], which its violation provides information on the intermodal correlations in the system. The first observation of this violation was obtained by Clauser, who used an atomic two-photon cascade system [@[3]]. More recently, strong violations using four-wave mixing have been adopted in [@[4]; @[5]]. Inthe dotted curve, i.e. the mode under consideration is in the Fock state, the $W(0,0)$ exhibits the maximum negativity at $r_3=0$, which monotonically decreases and completely vanishes at $r_3=4$. This shows for how long the nonclassicality inherited in the first mode survives based on the intensity of the third amplifier. On the other hand, form the dashed curve, i.e. the mode under consideration is in the vacuum state, the $W(0,0)$ exhibits negative values for $r_3\geq 1$, increases rapidly to show maximum around $r_3=2$, reduces gradually and vanishes for $r_3\geq 5$. This range of negativity is greater than that of the dotted curve. This is in a good agrement with the behavior of the second-order correlation function. Finally, comparison among the curves in Fig. 5(b) confirms the fact: for


certain values of the system parameters, the asymmetric case can provide nonclassical effects greater than those of the symmetric one.

Conclusion
==========

In this paper we have studied the three-mode squeezed operator, which can be implemented from the triply coincident nonlinearities in periodically poled $KTiOPO_4$. The action of this operator on the three-mode coherent and number states is demonstrated. We have studied quadrature squeezing, second-order correlation function, Cauchy-Schwartz inequality and quasiprobability distribution function. The obtained results can be summarized as follows. Generally, the single-mode vacuum or coherent states, as outputs from the three concurrent amplifiers are not nonclassical states. The system can exhibit two-mode and three-mode squeezing. The amount of the two-mode squeezing generated by the asymmetric case is much greater than that of the symmetric case. Three-mode squeezed coherent (number)means.

In sports, as in life, we can only control what we can control.

Basketball players can’t control a ref’s calls. But they can control how they react to bad calls. A player can’t control (or change) the fact that he just made a bad play. But he can control how he approaches the next play. A player can’t control whether a teammate works hard in drills. But he can control his own effort.

What’s Important Now is controlling whatever you can control . . . right now. In basketball, that means, playing the next play without worrying about the last or looking forward to one later in the game.

Bad call goes against you? Yelling at the ref is not what’s important now. What’s important now? The next play. Make a


bad turnover? Hanging your head is not what’s important now. What’s important now? Sprinting back on defense to stop the opponent who stole your pass.

It reminded me of W.I.N? None of us can control how others act or treat us. But every single one of us can control our response to how others act and treat us. And isn’t that almost always what’s important now?

As I thought about it, I thought back to my post President’s Day & Civility. It’s a post in which I referred to Linda Klein’s President’s Message in the February edition of the ABA Journal: One Word: Civility. Please read it.

President Klein wrote:

“As leaders in society, lawyers must ensure that civility once again becomes a quality that defines us. We need to set theand phosphorylation ([@bib35]; [@bib15]). The phosphorylation of DGCR8 conditions its ability to associate with cofactors. Although DGCR8 phosphorylation increased its stability, it did not alter its miRNA processing activity, suggesting novel functions for this posttranslational modification ([@bib15]). Importantly, noncanonical functions for DGCR8 have been recently discovered, including the binding to a large number of structured RNAs that harbor predicted secondary structures resembling that of a primary miRNA, and to cassette exons regulating the abundance of alternative spliced isoforms ([@bib25]). Finally, recent work revealed an interplay between pre-mRNA splicing and the microprocessor within the supraspliceosome ([@bib1]).

DGCR8's function is essential for mouse embryonic development, reflected by embryonic lethality postimplantation ([@bib36]). Interestingly, *Dgcr8* knockout (*Dgcr8*\_KO) mouse embryonic stem cells (mESCs) present proliferation and differentiation defects that slightly differ from those of


Fisher Scientific) with 2 µg plasmid per well. Cells were plated 24 h before transfection at 200,000 cells per well and cultured in culture medium without streptomycin and penicillin. The medium was changed to normal culture medium 8 h after transfection. After 3 d in the selection media, cells were single sorted into 96-well plates to achieve single-cell colonies. Cells were always cultured in selection media, and positive clones were screened at the DNA, mRNA, or protein level. For DGCR8 complementation, *Dgcr8*\_KO--complemented mESCs were achieved by stable transfection of mouse, human, and phosphomutant DGCR8 plasmids ([@bib15]). Stable independent mESC clones were selected in 250 µg/µl G418-containing medium. For the minigene and short inducible TCF7L1, stable clones were selected in 1 µg/µl puromycin--containing medium.

Plasmids {#s12}
--------

sgRNAs were individually cloned intoform.

Genomic DNA extraction and PCR {#s14}
------------------------------

mESCs were lysed (Tris-HCl 1M, EDTA 0.5M, SDS 20%, NaCl 5M, and ddH~2~O) for 4 h at 60°C using proteinase K at 1 mg/ml (Sigma-Aldrich). Genomic DNA was extracted from 1 × 10^6^ mESC pellets using Roti phenol/chloroform/isoamyl alcohol (Roth). Each PCR reaction was performed using 50 ng genomic DNA, and the PCR products were separated on a 1% agarose gel containing ethidium bromide. Genotyping PCR primer sequences are described in Table S1.

Quantitative RT-PCR analysis {#s15}
----------------------------

Total cellular RNA was extracted from 1 × 10^6^ mESC pellets using TriZOL Reagent (Thermo Fisher Scientific). Extracts quality was verified by loading 1 µg total RNA on a 1% agarose gel. A total of 2 µg cellular RNA was treated with DNase (RQ1 Rnase-Free DNase kit; Promega)


All membranes were probed with an anti--α-tubulin antibody or Coomassie blue staining to ensure equal loading.

Low-molecular-weight Northern analysis {#s17}
--------------------------------------

Total cellular RNA was extracted from 1 × 10^6^ mESC pellets using TriZOL Reagent (Thermo Fisher Scientific). A total of 10 µg total RNA was resuspended in 30 µl final of 50% deionized formamide, loaded on a 17.5% acrylamide gel (30% acrylamide/bis solution 19:1; Bio-Rad Laboratories), blotted for 1 h on a nylon membrane (Amersham Hybond-NX; GE Healthcare) in 0.5× TBE (Tris/borate/EDTA) buffer at 25 V and 1.5 mA per square centimeter of membrane in a semidry system. Membranes were then ethyl-dimethyl-aminopropylcarbodiimide cross-linked. Prehybridizations and hybridizations were both performed in PerfectHyb Plus Hybridization Buffer (Sigma-Aldrich) at 42°C. All washes were performed in SSC 2×, SDS 0.1%. Radioactive signals were detectedinput samples and the remainder used for immunoprecipitation. 10 µg anti-DGCR8 (Proteintech) or anti-IgG (Sigma-Aldrich) antibody was bound to Sepharose beads (Protein A; Invitrogen) in the presence of heparin. Precleared lysates were then incubated with the appropriate antibody-bound beads, and the immunoprecipitated proteins were then washed (150 mM KCl, 25 mM Tris, pH 7.4, 5 mM EDTA, 0.5 mM DTT, 0.5% NP-40, and RNase, protease, and phosphatase inhibitors) and incubated with DNase I in the presence of DNase buffer (Promega) followed by protease K (New England Biolabs, Inc.) in the presence of 2× protease buffer (New England Biolabs, Inc.). RNA extraction was then performed using phenol-chloroform extraction and ethanol/sodium acetate precipitation. RNA pellets were washed in ethanol, resuspended in 100 µl water, and quantified using a BioPhotometer (Eppendorf).

Exit


Technologies) and up to 2 µg poly(A)-purified RNA was used for the library preparation TruSeq Paired-end stranded RNA Preparation kit (Illumina) according to the manufacturer's instructions. Library preparation and sequencing (Illumina HiSeq 2000) were performed at the Functional Genomics Center Zurich. Paired-end sequencing generated ∼2 × 60 million reads per library. Reads from RNA-seq were first preprocessed by trimmomatic (v0.32; [@bib6]) to remove low-quality ends and adapters. Then, reads were aligned to mouse genome mm10 by STAR (v2.4.2a; [@bib11]) allowing for at most two mismatches. FeatureCount (v1.4.5-p1; [@bib22]) was used to count reads for each gene (Ensembl GRCm38.78), ignoring reads on overlapped regions and multiple-hit reads. Differentially expressed genes were defined by both edgeR (v3.12.0; [@bib31]) and DESeq2 (v1.10.0; [@bib24]), with fold change greater than two and falseProduct Availability

Description

Store all you need on your camera, smart phone or tablet with the ultra-efficient SanDisk Extreme microSDHC/microSDXC Memory Card Capable of holding reams of video, images, music and data, this memory card boasts super-fast transfer speeds and will prove durable in even the most extreme conditions.

This amazing 32GB micro SD card will save you plenty of time in moving your data from your handheld device to your computer, with read speeds of up to a lightning-fast 80MB/s offering an ultra-smooth transition.

Long-Lasting

An incredibly durable design means the waterproof and shockproof SanDisk Extreme microSDHC will survive just about any environment, remaining operational in temperatures ranging between -25°C and 85°C.

Specifications

Specifications

Brand

SanDisk

Model

SDSDQXL-032G-G46A

Product Type

Micro SD Card

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Ask Us

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Coroner: Truck that lost corpse due to be retired

FEASTERVILLE, Pa. (AP) — Wear and tear on a pickup truck used to transport bodies caused a hatchback to open and a corpse to fall on to a busy highway, an apologetic coroner in Pennsylvania said.

Bucks County Coroner Joseph Campbell identified the body as that of a young woman who died of an apparent drug overdose. His office has contacted her family.

"It was a horrible thing," Campbell told the Bucks County Courier Times. "I can't tell you how upset I was."

Bystander Jerry Bradley saw the gurney Friday in the busy four-lane road as he pulled out of a nearby shopping center in Lower Southampton Township and took a photograph that has been circulating online. He said he helped the transportQ:

css transition opacity fade background

I am doing a transition where it fades into transparent white, when a user is hovering an image.
My problem is that I need to change the color, that it fades to, to black. I have tried just simply adding background:black; to the class that contains the transition, but it does not work unfurtunately, it's still fading into white transparent.
The css code I am using is:

.hover:hover {
  opacity: 0.2;
}

.item-fade {
  background: black;
  opacity: 0.8;
  transition: opacity .25s ease-in-out;
  -moz-transition: opacity .25s ease-in-out;
  -webkit-transition: opacity .25s ease-in-out;
}

Hover image, the white opacity needs to be black :/

A:

Wrap your image into a SPAN element that has the background: black;

.imgHolder{
  display: inline-block;
  background: #000;
}
.item-fade{
  vertical-align:


Introduction {#s1}
============

Chronic inflammation and increased self reactivity are the hallmarks of aging and are thought to be the underlying cause of the many age-associated diseases such as Alzheimer\'s; Rheumatoid Arthritis \[[@R1]\]. The mechanisms responsible are not well understood. It is well established that the immune system undergoes significant alterations with age. The consequences of progressive aging of the immune system include an increase in autoimmune phenomena, incidence of cancer, chronic inflammation, and predisposition to infections \[[@R2]-[@R5]\]. This suggests a decrease in the protective immune responses to exogenous and infectious agents, and an increase in reactivity to self or endogenous danger signals. Several factors may be responsible for the increased reactivity to self, including loss of immune tolerance, and progressive age-associated loss of tissue integrity yielding new self-antigens. Anotherrequires its intracellular delivery. These data suggest that aging leads to alterations in DNA that enhance its immunogenicity, and may contribute to age-associated chronic inflammation and autoimmune phenomenon.

DNA from aged subjects is demethylated compared to DNA from young subjects {#s2_2}
--------------------------------------------------------------------------

Next, we investigated the age-associated alterations in the DNA that may be responsible for its increased immunogenicity. Aging is associated with increased apoptosis \[[@R24]\], which may result in shorter fragments of DNA. Running the DNA on gel showed that the size of DNA obtained from both aged and young subjects was comparable (Figure [2A](#F2){ref-type="fig"}). Accumulation of DNA damage due to either oxidation or inefficient DNA repair mechanism is another characteristic of advancing age \[[@R15],[@R16],[@R25]\]. Therefore, we compared the DNA damage between aged and young DNA \[damage of 25 separate


days and DCs (CD14^-^HLA-DR^+^CD11c^+^cells) were collected after 6 days. The purity of the DC was \>95% as determined by the expression of CD14, CD11c and HLA-DR.

[Self DNA Preparation.]{.ul}DNA was isolated from the blood of aged and young subjects using Qiamp DNA Blood Midi Kit from Qiagen (Valencia, CA). RNase was added to remove any contaminating RNA. Purity and yield of DNA was measured by UV spectrophotometer. Preparations with 260/280 ratio above 1.9 were used in all experiments. DNA obtained was free of endotoxin contamination as determined by Limulus amoebocytelysate (LAL) assay (Lonza Inc, Allendale, NJ).

[DC activation.]{.ul}Transfection reagent Lipofectamine 2000 (Invitrogen, Carlsbad, CA) was used to deliver self DNA to DCs. DNA was mixed with lipofectamine (lipo) in 100 μl of Opti-MEM for 20 minutes at room temperature, accordingusing the DNA damage quantification kit.

[Quantification of DNA damage.]{.ul} DNA damage from aged and young subjects was quantified using DNA damage Quantification kit from BioVision (Mountain View, CA) following the manufacturer\'s protocol. This kit determines the number of abasic sites in purified DNA samples utilizes the ARP (Aldehyde Reactive Probe) reagent that reacts specifically with an aldehyde group, which is the open ring form of the Apurinic/apyrimidinic ( AP) sites.

[Statistics.]{.ul} Statistical analysis was performed using GraphPad Prism™ 4.00 software (GraphPad Software, San Diego, USA). Unpaired data were analyzed with the Mann-Whitney test. Wilcoxon signed ranked test was used for paired analyses. Statistical significance was acknowledged when the *P*-value was \<0.05.

This study is supported in part by grant AG027512 from NIH and by New Scholar grant from the Ellison


      e.g. MooEvent, EVT_MOO = NewEvent()
    """
    evttype = wx.NewEventType()

    class _Event(wx.PyEvent):
        def __init__(self, **kw):
            wx.PyEvent.__init__(self)
            self.SetEventType(evttype)
            self.__dict__.update(kw)

    return _Event, wx.PyEventBinder(evttype)

def NewCommandEvent():
    """Generate new (CmdEvent, Binder) tuple
        e.g. MooCmdEvent, EVT_MOO = NewCommandEvent()
    """
    evttype = wx.NewEventType()

    class _Event(wx.PyCommandEvent):
        def __init__(self, id, **kw):
   need, "Get up, pick up your mat, and go home!" Act on a truth, and only then does it become _your_ truth. (Matthew 9:6). The real healing for the paralyzed man was the courage to act _as if_ —and then his mind and body followed in step.

This total realignment of the self is often portrayed in the Gospels as new self-confidence, new capacities for relationship, new joy, forgiveness of the old self—and all of these are made recognizable by the physical cure. (I am not denying physical healing; in fact, I have seen it happen more than once, even in myself.). The Bible did not have all the abstract psychospiritual, cultural, and relational language we have today. The biblical just saw embodied people not making it in life—and


proven; it is a manifestation of the wholeness that we are all meant to experience, even in this world—not time as "chronological moments of endless duration" _but time as momentous and revealing the whole_.10 When "time comes to a fullness" (Mark 1:15) as in a moment of love, childbirth, union, peaceful death, or beauty, you have then experienced a moment of eternal life. Resurrection is when one moment reveals the meaning of all moments. Without such moments, it will either be very hard for you to imagine resurrection or, conversely, you will long for it like no one else, which is the concise meaning of the virtue of hope.

The Risen Christ is the standing icon of humanity in its final and full destiny. He is the pledge andSt Helen's Church, Stapleford

St. Helen's Church Stapleford is a parish church in the Church of England in Stapleford, Nottinghamshire.

The church is Grade II* listed by the Department for Culture, Media & Sport as it is a particularly significant building of more than local interest.

Stapleford cross in the churchyard is listed Grade I, and is also a scheduled ancient monument.

History

The church is medieval but was heavily restored in 1878 by T. G. Jackson.

Stone Cross

The churchyard contains a grade-I listed stone cross which dates from around AD1000. It was said by Pevsner to be "by far the most important pre-Conquest monument in Notts."

The cross may be the origin of the name 'Stapleford' which means a crossing near a post.

Memorials
Robert Tevery, died 1571
Gervase Tevery, died 1639
George John Borlase Warren, died 1801

Current


Project Summary The State Hygienic Laboratory (SHL) proposes to 1) maintain and enhance the current ISO/IEC 17025:2005 accreditation for the microbiological and chemical analysis of food testing, 2) partner with Iowa Department of Inspection and Appeals to perform surveillance sampling and testing for FDA's Manufactured Food Regulatory Program, and 3) use next generation sequencing technique to analyze foodborne related pathogen isolates and upload the data into the NCBI database for data sharing. SHL will adopt a continuous improvement approach based on the PDCA management method (Shewhart cycle) to maintain and enhance the current SHL laboratory quality management system. SHL will continue to conduct management review and internal audit, actively seek customer feedback and utilize the best practices to improve the laboratory service quality. For ISO scope enhancement, SHL UnlockBuffersRead(device);
    ALCcontext_DecRef(context);
}

AL_API void AL_APIENTRY alBufferSubSamplesSOFT(ALuint buffer,
  ALsizei offset, ALsizei samples,
  ALenum channels, ALenum type, const ALvoid *data)
{
    ALCdevice *device;
    ALCcontext *context;
    ALbuffer *albuf;
    ALsizei align;

    context = GetContextRef();
    if(!context) return;

    device = context->Device;
    LockBuffersRead(device);
    if((albuf=LookupBuffer(device, buffer)) == NULL)
        SET_ERROR_AND_GOTO(context, AL_INVALID_NAME, done);
    if(!(samples >= 0 && offset >= 0))
        SET_ERROR_AND_GOTO(context, AL_INVALID_VALUE, done);
    if(IsValidType(type) == AL_FALSE)
        SET_ERROR_AND_GOTO(context, AL_INVALID_ENUM, done);

    WriteLock(&albuf->lock);
    align = ATOMIC_LOAD_SEQ(&albuf->UnpackAlign);


 SET_ERROR_AND_GOTO(context, AL_INVALID_NAME, done);
    if(!(samples >= 0 && offset >= 0))
        SET_ERROR_AND_GOTO(context, AL_INVALID_VALUE, done);
    if(IsValidType(type) == AL_FALSE)
        SET_ERROR_AND_GOTO(context, AL_INVALID_ENUM, done);

    ReadLock(&albuf->lock);
    align = ATOMIC_LOAD_SEQ(&albuf->PackAlign);
    if(SanitizeAlignment(type, &align) == AL_FALSE)
    {
        ReadUnlock(&albuf->lock);
        SET_ERROR_AND_GOTO(context, AL_INVALID_VALUE, done);
    }
    if(channels != (ALenum)albuf->FmtChannels)
    {
        ReadUnlock(&albuf->lock);
        SET_ERROR_AND_GOTO(context, AL_INVALID_ENUM, done);
    }
    if(offset > albuf->SampleLen || samples > albuf->SampleLen-offset)
         SET_ERROR_AND_GOTO(context, AL_INVALID_VALUE, done);
        }

        albuf->LoopStart = values[0];
        albuf->LoopEnd = values[1];
        WriteUnlock(&albuf->lock);
        break;

    default:
        SET_ERROR_AND_GOTO(context, AL_INVALID_ENUM, done);
    }

done:
    UnlockBuffersRead(device);
    ALCcontext_DecRef(context);
}

AL_API ALvoid AL_APIENTRY alGetBufferf(ALuint buffer, ALenum param, ALfloat *value)
{
    ALCdevice *device;
    ALCcontext *context;
    ALbuffer *albuf;

    context = GetContextRef();
    if(!context) return;

    device = context->Device;
    LockBuffersRead(device);
    if((albuf=LookupBuffer(device, buffer))


  {
        ALBuf->OriginalChannels = (enum UserFmtChannels)DstChannels;
        ALBuf->OriginalType     = (enum UserFmtType)DstType;
        ALBuf->OriginalSize     = frames * NewBytes * NewChannels;
        ALBuf->OriginalAlign    = 1;
    }

    ALBuf->Frequency = freq;
    ALBuf->FmtChannels = DstChannels;
    ALBuf->FmtType = DstType;
    ALBuf->Format = NewFormat;

    ALBuf->SampleLen = frames;
    ALBuf->LoopStart = 0;
    ALBuf->LoopEnd = ALBuf->SampleLen;

    WriteUnlock(&ALBuf->lock);
    return AL_NO_ERROR;
}

ALsizei BytesFromUserFmt(enum UserFmtType type)
{
    switch(type)
    {
  merits" [Doc. Nos. 54 & 79]. ESW's motion for summary judgment was filed in August of 2003. [Doc. No. 9]. Kohler opposed the motion at that time, and later filed a cross motion for summary judgment contending that it is entitled to summary judgment. [Doc. No. 83].
ESW was a distributor of Kohler small engines pursuant to a contract known as the central warehouse distributor agreement or "Kohler Engine Distributor Agreement" ("Agreement"). (Kohler's Exhibit 1). At the time the instant controversy arose, the parties were operating under the most recent version, signed in 1995. Id. The Agreement provides for termination of the contract in the last paragraph on page one stating in pertinent part:
This agreement shall remain in effect until terminated by either party upon ninety (90) days' written


local "retailers."
A. Definitions in the Wholesaler Act
As this dispute turns on the interpretation of the statute, the Court begins with the definitions provided in the Wholesaler Act. ESW contends that it is entitled to the protections provided by the Wholesaler Act as a "dealer." Kohler asserts that ESW is an "agent" and therefore not protected as a "dealer" under the Wholesaler Act. First, the Court considers the applicability section of the Wholesaler Act, Section 51:481(A), which provides:
The provisions of this Part shall apply to written contracts or oral agreements of definite or indefinite duration between any person, firm or corporation engaged *833 in the business of selling, distributing or retailing farm, construction, heavy industrial material handling, utility and lawn and garden equipment, engines, implements, machinery, attachments and repairdealer, lawn and garden equipment dealer or retail equipment distributor dealer.
La. R.S. § 51:481(B)(3). This "meaning" is in fact only a list of the different types of dealers. Id. "Retailer" is not defined in Part B or anywhere else in the act.
Furthermore, although the meaning of "dealer" is found in Part B, the term "dealer" is not found in Part A of the same section. Section 51:481(A) does refer to the term "retailer," but "retailer" is not found in the rest of the act. On the other hand, "dealer" is used throughout the Wholesaler Act. From the plain words of the statute, it is unclear whether "retailer" and "dealer" are interchangeable or whether "retailer" is a class of "dealer." Therefore, the Court finds that the Wholesaler Act is


was with the implied permission of the owner, Ralph Gilster Jr. and that its operation was within the scope of the use for which it was loaned.
"3. That the policy of insurance issued by Allstate Insurance Company is secondary coverage in connection with the accident made the basis of this suit."
From a judgment declaring the respective rights of the two insurance companies contrary to the contentions of Phoenix, and in accordance with the findings and conclusions reached by the trial court, Phoenix has appealed. By its fifteen points of error, it raises questions of legal and factual insufficiency of the evidence to support the court's findings Nos. 8, 10, 11, and 12, (Garza v. Alviar, Tex.Sup.Ct., 395 S.W.2d 821) and states that the court erred in each ofCatholic Youth Organization, had on prior occasions driven other cars borrowed by Father Stiles for out of town trips in connection with church work, and Father Stiles expressed complete confidence in him and his driving. In fact, the Father testified that he was afraid to drive this particular car and felt safer with some one else driving.
*336 Findings of Fact Nos. 6 and 7 are based on undisputed evidence, and are not objected to or attacked by appellant. With reference to such findings, and to the second clause of the second Conclusion of Law, we quote as follows from 7 Am.Jur.2d, § 117, p. 435:
"The `general rule' that a permittee may not allow a third party to `use' the named insured's car has generally been held not to


double-dating with French. While they were at the dance French, allegedly with McCauley's permission, though this is disputed, used the car to take his date to her dormitory within the time required by dormitory rules. While on the way back to the dance French was involved in a car accident. Although nothing was said by Rockwell about French driving, there was no express limitation that only McCauley was to drive. The policy in question covered Rockwell as the *337 named insured, and "any person using such automobile, provided the actual use thereof is with the permission of the named insured." The Court of Civil Appeals, in reversing and rendering the trial court's judgment, held that French was using the car without the express or implied consent of Rockwell,and was not covered by the above quoted provision of the policy.
While we do not take issue with the decision in French, we do believe that it is not applicable or controlling in the fact situation in our case. As stated in the above quotes from 4 A.L.R.3rd and 7 Am.Jur.2d, supra, in each case a factual determination must be made as to whether the initial grant of permission was broad enough, under all of the surrounding facts and circumstances, to include an implied grant to the first permittee to give another authority to operate the automobile. In our case the evidence was that the car was loaned to Father Stiles, not as a private individual on a private mission, but as assistant pastor and Youth Director of


months ago saying they are going to open up banking, insurance and a couple of additional sectors to foreign investment; nothing happened.

The reason was that the head of that division got changed. A new administrator came in who was not sure what the president wanted so he did nothing. Time went on and the international community said, “Wait a minute, you promised that you were going to do that and you didn’t do that.”

So the structure is such that it is very difficult. China can’t react as fast as it should. That will change, but it is going to take time.

R&I:That’s interesting, because during the financial crisis in 2008 there was talk that China, given their more centralized authority, could react more quickly, not less quickly.

Hank Greenberg: Itwill take place, there is no doubt about it.

Advertisement

More will go on in space, there is no question about that. We’re involved in it right now as an insurance company, and it will get broader.

One of the things you have to worry about is it’s now a nuclear world. It’s a more dangerous world. And again, we have to find some way to deal with that.

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section */
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This article builds on the work of Case-Smith and colleagues and proposes a roadmap to guide future research in occupational therapy. To foster best practice in the application of principles and practices of sensory integration (SI), the pillars of practice, advocacy, and education are identified as elements that provide the foundation for research. Each pillar ensures that SI research is conducted in a rigorous and relevant manner. To this end, achievements to date are discussed, with proposed goals presented for each pillar. Finally, the roadmap builds on the pillars and outlines implications for occupational therapy with the overarching theme that a wide array of scientists, educators, therapists, and service recipients will be needed to ensure that those who


that a unique number, incremented each time, is not the best way to handle identifying cars!

As it turns out, part of the code is a unique number assigned to a single car of a single model at a single manufacturer, but much of the information contained in a VIN is not unique. Now, knowing about how the VIN works won’t save you any money on gas but now you’ll know something few people do!

Not too long ago, for Spring Break, my son and I took a road trip to Arizona to visit my grandfather. One thing I noticed: As I drove farther south, the gas prices rose. By the time we reached Arizona, we were paying more than $4.00 per gallon!

I’m not the only who has noticed abra store woocommerce themes

If you need to create an online store to sell bras and underwear, then you have to check out these WooCommerce themes. These WooCommerce themes are made for lingerie stores, and they come with useful features like SEO optimization, Google… Continue Reading →


Q:

Error message when trying to open user profile from responses page, but only for answers

If you are trying to open a user profile from responses (from answers tab) error message will appear:

Error occurred while opening post body

No errors in console.
FF 72.0.1 (64-bit).

A:

This was an issue that only happened in FF. It is now fixed.

a result, there is a hodge-podge of regulatory standards regarding home inspectors. Each province has its own regulatory requirements if they have any requirements at all. For instance, in 2009, the B.C. government was the first to pass the Home Inspector Licensing Regulation which required all home inspectors to have certification.

Believe it or not, B.C. was the first province to require home inspectors to pass regulated education requirements and to become provincially licensed. In 2011, Alberta followed and passed the Home Inspection Business Regulation. As a result, home inspectors operating in this province are now required to pass and qualify for provincially managed certification.

Most recently, Ontario joined the club. In 2017, the provincial government finally passed the Home Inspection Act which holds standards for contracts, reports, and disclosure


Our discussion and analysis of the Oklahoma Clean Water State Revolving Fund Loan Account Administrative Fund's financial performance provides an overview of the Fund's financial activities for the fiscal year ended June 30, 2011. Please read it in...

The Board of Regents for Oklahoma Agricultural and Mechanical Colleges hereby respectfully submits the enclosed biennial statements, inventories, and reports for all the educational institutions and agencies under the jurisdiction of this Board of...

This Technical Assistance Document for School Finance should be utilized to complement the statutes and regulations. It is presented in an easy-to-use format using a combination of actual statutory/regulatory provisions and an easy-to-understand...

I am pleased to issue the fiscal year 2013 annual investment performance report for the Office of the State Treasurer. The report provides details on investmentmilitary balance in the region, in addition to having no adverse impact on U.S. defense readiness as a result of the sale.

Raytheon Missile Systems, out of Tucson, Ariz., will provide the equipment and support for the Royal Canadian Air Force.

RELATED Royal Canadian Navy awards Thales support contract for up to 35 years

RELATED Canadian armed forces to receive new machine guns


is supplemental or auxiliary
information, because it has this visual cue.

Of course, sacrificing readability to achieve this definitely isn't the best
MO.

------
polskibus
reddit on the whole is similar, isn't it ?

~~~
readme
Technologically, yeah. The community? Not a chance. And as far as the code
goes, one is way better off creating a couple tables and making their own
clone than re-using reddit's code.

Secondly, we chose an established model for patulin genotoxicity, i.e. the chromosomal aberration assay in V79 Chinese hamster cells, to clarify whether concomitant exposure to ascorbic acid with the mycotoxin modulates or not the clastogenicity of patulin. The results unequivocally show induction of DNA-damaged cells by patulin as assessed by both cytogenetic assays. In addition, an almost complete abolition of patulin (0.8 microM) clastogenicity was observed in the presence of 80 microM ascorbic acid (P < 0.05), showing that although a genetic risk is present, ascorbic acid could somehow partially modulate this problem.


Weight reduction utilizing a protein-sparing modified fast.
Forty-five grossly obese patients (averaging 64.1 kg. above ideal body weight) were treated as in-patients with a modified protein-sparing fast. Twenty-seven of these patients had diabetes, sixteen of them requiring insulin. In-patient treatment with PSMF ranged from three days to two years. The dietary regimen provided 1.2 gm. protein per kilogram ideal body weight, with no added fat or carbohydrates; this generally amounted to 270 to 430 gm. meat, distributed in three meals (about 500 to 800 kcal per day). Generous vitamin and mineral supplements were provided. Concomitant psychotherapy was also part of the treatment. Before discharge, the patients had lost from 0.45 to 93.2 kg., depending on compliance, length of hospitalization, and amount of exercise. After discharge, compliance fell, despite provisionit was a dilemma that wasn’t really a dilemma.

"I have to work. I respect the decision and if I can’t complete my hours there, then I will do it somewhere else. It isn’t an issue."

Henry went on to admit that while he is keen to get into management, it is unlikely to happen for quite some time, as he aims to earn all of the relevant badges first.

"I would like to manage, but I am far from it.

"First and foremost, make sure you have everything, all the badges.

"Then we will see."


Safety Analysis of Brentuximab Vedotin from the Phase III AETHERA Trial in Hodgkin Lymphoma in the Post-Transplant Consolidation Setting.
The phase III AETHERA trial demonstrated the efficacy of brentuximab vedotin (BV) as consolidation therapy in patients with classical Hodgkin lymphoma (HL) at high risk of relapse or progression after autologous hematopoietic stem cell transplantation (auto-HSCT; hazard ratio, .57; P < .001). The objective of this analysis is to provide further detail on the most common and clinically important treatment-emergent adverse events (AEs) in the AETHERA BV arm including their occurrence and management. AEs of clinical importance occurring in patients who participated in AETHERA (BV + best supportive care [BSC], n = 165; placebo + BSC, n = 164) were evaluated for time to onset, manageability through dose modification, andI really don't fancy this using ℕ
  suffices : fibZ(m+n+1)=fibZ(m+1)*fibZ(n+1)+fibZ(m)*fibZ(n),
  { simp only [fibZ_eq_fib] at this,
    norm_cast at this,
    assumption},
  refine induction2 _ _ _ _ n,
  { simp},
  { show fibZ (m + 2) = fibZ (m + 1) * 1 + fibZ m * 1 ,
    rw fibZ_succ_succ,
    simp [add_comm]},
  { -- inductive step
    intros d h1 h2,
    show fibZ (m + (d + 1) + 2) = fibZ (m + 1) * fibZ ((d + 1) + 2) + fibZ m * fibZ (d + 2),
    rw fibZ_succ_succ d,
    rw fibZ_succ_succ (d+1),


support a program which recognises and celebrates the volunteers who give back to the sport of rugby within the Taranaki community.

Our Athletes In Schools program gives young people in schools around our region the opportunity to engage with an Olympic medalist and learn about the dedication and focus that it takes to perform at the highest level.

As a social enterprise, inspiring the next generation of social innovators is also important to us, and this year we introduced a Social Innovation Award as part of the New Zealand Young Enterprise Scheme in Taranaki. The aim of the award is to encourage the aspiring young business leaders in our community to actively consider how they can develop businesses concepts to deliver sustainable positive impacts.

The Fund is primarily funded by InternationalDisorders of temperature regulation: prehospital implications.
Humans are warm-blooded mammals and must maintain a constant internal temperature. Body temperature is controlled by the hypothalamus in the brain, with input from sensory receptors throughout the body. At any given time, body temperature is a function of heat production and heat loss. Temperature-regulation problems can result in several conditions. These include fever, hyperthermia and hypothermia. EMTs and paramedics must be familiar with the physiological and pathophysiological processes resulting from these disorders. By close observation of the patient, it should be fairly easy to determine which underlying processes are causing the observed signs and symptoms. With this knowledge, you can provide competent, compassionate prehospital care.


    string index = "pdftestitems";

            Console.WriteLine("client stuff...");

            var node = new Uri("http://tns-dev.pts-eden.org:9200");
            var settings = new ConnectionSettings(node).SetDefaultIndex(index);
            var client = new ElasticClient(settings);

            Console.WriteLine("deleting index...");

            // delete index if any
            var di = client.DeleteIndex(index);

            Console.WriteLine(di.ConnectionStatus.HttpStatusCode);

   GAGs. As expected, in nonwounded skin there was light alcian blue staining indicating that there is a low level of constitutive GAG expression in the ECM ([Fig. 2, A and B](#fig2){ref-type="fig"}). In wild-type mice, 3-d-old wounds had intense alcian blue staining directly under the wound site emanating from the damaged area ([Fig. 2](#fig2){ref-type="fig"} C). By day 5 after wounding the level of staining in wild-type skin decreased and was contained in the hypodermis (unpublished data). In contrast, the γδ-deficient mouse skin displayed less intense alcian blue staining restricted to the hypodermis near the wound site 3 d after injury indicating reduced GAG expression ([Fig. 2](#fig2){ref-type="fig"} D). By day 5 after wounding, the alcian blue staining in the TCRδ^−/−^ skin intensifies under the injured site, appearing at levels similar


to the wild-type day 3--wounded skin but less localized (unpublished data). This delay in GAG expression is consistent with the delay in macrophage entry ([Fig. 1](#fig1){ref-type="fig"}) and the delay in wound repair we have previously reported for mice lacking γδ DETC ([@bib3]).

![Decreased levels of hyaluronan are deposited in the ECM of TCRδ^2/−^ mice 3 d after wounding. Alcian blue staining was performed on 5 μm paraffin sections from nonwounded (A and B) or day 3 (C and D) wild-type (A and C) and TCRδ^−/−^ (B and D) mouse wounds. Blue stain represents GAG deposition. To identify the GAG as hyaluronan, biotinylated hyaluronan binding protein was used to stain wild-type (E) or TCRδ^−/−^ (F) day 3--wounded skin. Wild-type (G--L) or TCRδ^−/−^ (not depicted) wounded skin was preincubated with orng/ml FGF-10 (G). In some cases the keratinocyte growth factor receptor blocking peptide at 10 μg/ml (D and F) or vehicle control (H) was added. Cells were stained with phycoerythrin-labeled hyaluronan binding protein (top) and DAPI (bottom). Digital images of representative cells from at least three experiments were acquired at ×200 magnification.](20042057f5){#fig5}

A likely candidate for the induction of HAS 2 and 3 is FGF-7. This growth factor has recently been shown to induce HAS 2 and 3 expression in rat keratinocytes ([@bib31]). FGF-7 and keratinocyte growth factor-2 (FGF-10) bind the same receptor expressed on keratinocytes, FGFR2IIIb ([@bib34]--[@bib36]). Both factors are produced by DETC upon TCR stimulation and act in a paracrine fashion on keratinocytes ([@bib3], [@bib30]). DETC-produced keratinocyte growth factors play a key role in keratinocyte proliferation during


wound repair ([@bib3]) and have been shown to be the most important DETC-produced factors for keratinocyte proliferation ([@bib30]). To determine whether FGFR2IIIb binding results in up-regulated HAS 2 and 3 expression in mouse keratinocytes, recombinant FGF-7 was added to PAM cells. RT-PCR revealed that both HAS 2 and 3 are up-regulated by FGF-7 ([Fig. 4](#fig4){ref-type="fig"} B). This correlates well with the previously published results in rat keratinocytes ([@bib31]).

To examine whether this increase in hyaluronan synthase expression results in increased production of hyaluronan, we cultured the keratinocytes with recombinant FGF-7 and stained for hyaluronan using the fluorescent-labeled hyaluronan binding protein. Addition of FGF-7 resulted in increased hyaluronan production, even at concentrations as low as 20 ng/ml ([Fig. 5](#fig5){ref-type="fig"} E). The other FGFR2IIIb ligand, FGF-10, is also produced by DETCfield demonstrated that there were only 10 ± 5 macrophages per field in mice receiving buffer alone, whereas there were 43 ± 7 macrophages per field upon addition of either KGF-1 or HA. Wild-type mice receiving KGF-1 or HA showed no differences in macrophage migration at this time-point (Fig. S2). Taken together this data supports a role for γδ T cell--produced keratinocyte growth factors in mediating hyaluronan deposition and subsequent macrophage migration to the wound site. Mice deficient in γδ T cells not only lack γδ T cell--produced hyaluronan, but also the rapid mobilization of keratinocyte growth factors to the epithelial cells that induces keratinocyte production of hyaluronan.

Discussion
==========

γδ T cells are considered by many to bridge the gap between innate and adaptive immunity. Adaptive responses by αβ T


wild-type mice. Therefore the delay in hyaluronan production we describe in TCRδ^−/−^ mice does not result in delayed neutrophil entry. In contrast, macrophage entry into wild-type wounds occurs by day 3, concurrent with hyaluronan deposition. In this study we observe defects in macrophage entry to the wound site in TCRδ^−/−^ mice that can be restored with the addition of high molecular weight hyaluronan into the wound site. This formally demonstrates that hyaluronan is a key mediator of inflammation and macrophage migration during wound repair.

Hyaluronan is synthesized at the plasma membrane by HAS 1--3, which have been shown to be regulated by several different factors ([@bib31], [@bib42]). Although we found very little, if any, hyaluronan synthase expression in the epidermis before wound administration, by day one after wounding sustainedDETC regulate the tissue in which they reside to support macrophage migration. γδ IELs in other tissues such as the lung have also been implicated in the initiation of inflammatory cell infiltration ([@bib45]) and may also induce epithelial hyaluronan production. Furthermore, therapies that stimulate epithelial γδ T cells to rapidly produce keratinocyte growth factors and mobilize inflammatory cells to the damaged site may be useful in patients with wound healing complications, such as diabetics. Our findings demonstrate a novel interaction between the immune system and wound repair, which may aid in the development of future therapies for chronic nonhealing wounds.

Materials and Methods
=====================

Animals and wounding procedure
------------------------------

TCRδ^−/−^ mice on the C57Bl/6 background were purchased from the Jackson ImmunoResearch Laboratories. C57Bl/6 (wild-type) and TCRδ^−/−^ mice were bred at The Scripps Research


20 min, permeabilized in 0.3% Triton X-100 in PBS with 3% BSA for 20 min, incubated with 3 μg/ml biotinylated hyaluronan binding protein for 90 min, washed with PBS, and subsequently incubated with 1 μg/ml streptavidin--phycoerythrin (Biomeda) for 45 min. Slides were fixed in mounting media with DAPI (Oncogene) and digital images were acquired. In some experiments keratinocyte growth factor receptor peptide inhibitor (10 μg/ml) or control vehicle (1% DMSO) were added before stimulation ([@bib30], [@bib37]). Results are representative of at least three separate experiments.

Immunohistochemistry
--------------------

Mice were killed and the complete wounds including 2 mm of the epithelial margins were excised, fixed in ethanol, and embedded in paraffin. Sections were prepared and stained with biotinylated antibodies to Gr-1 (BD Biosciences), CD3 (BD Biosciences), F4/80 (Caltag), MHC class II (M5/114;asked if he knew anyone who could make  the Roadmaster disappear. Ochoa told McLaughlin  that he was having severe financial problems and  difficulty in paying the loan for the Roadmaster.  McLaughlin explained that he then contacted  Strange and asked if Strange could dispose of the  car. McLaughlin further told Agent May that Ochoa  had made copies of the keys to the Roadmaster in  order to retain the original keys, which would  support Ochoa's claim that the car had been  stolen.

12
As trial approached, the FBI again attempted to  locate McLaughlin to serve him with a subpoena to  appear. Agents returned to Garza's residence  where McLaughlin was still receiving mail. Garza  informed the FBI that McLaughlin


permitted McLaughlin to make  these calls, the evidence in this case is not  sufficient for Ochoa to have forfeited his  constitutional rights. Rule 804(b)(6) requires  the conduct at issue to be wrongful, and  permitting a witness at one's upcoming trial to  use a phone, without more, is not a culpable act.  The government has not produced evidence that  Ochoa knew McLaughlin was intending to flee, and  thus has not proven that Ochoa knowingly aided  McLaughlin in becoming unavailable. If Ochoa did  not know that he was helping McLaughlin to  procure McLaughlin's unavailability, then Ochoa's  conduct could not have been wrongful as required  by the Rule.3

31
4.  Harmless error.

32
The admission of McLaughlin's hearsay statements the Roadmaster was made during the time prior  to April 3, 1995, so that Ochoa could retain the  originals and the copies could be delivered to  the chop shop. Ochoa retained the original set of  keys to make his claim of theft more believable,  while the copies permitted the Roadmaster to be  delivered to the chop shop undamaged. Strange  told Agent Haman that the owner of the Roadmaster  intended to file a fraudulent insurance claim,  and Ochoa was the car's owner. The government  presented additional evidence as well. Strange  was paid only $350, indicating that he was  brokering the car between Ochoa and a chop shop,  since he could have sold the parts of a


   240
24/09    240
23/09    200
22/09    250
21/09    200
Then I can sum the columns across each file and get a total balance on each day like this:
Both Banks
Date    Amount
25/09    1640
24/09    1490
23/09    1450
22/09    1485
21/09    1235
Thanks I hope this is clear enough (and clearer after edit.

A:

By using pd.concat and bfill
BB.Amount=np.nan
df=pd.concat([BA,BB.loc[~BB.Date.isin(BA.Date),:]],axis=0)
df.reset_index(drop=True).sort_values('Date',ascending=False).bfill()

then, You got your dataframe Bank A
Out[1240]:
    Date  Amount
0  25/09  1100.0
1  25/09  1400.0
4  24/09  1250.0
2  23/09  1250.0
5  22/09  1235.0
6  21/09  1235.0
3  20/09  1235.0

Edit :
dfA=dfA.set_index('Date')
dfB=dfB.set_index('Date')
dfA.groupby(level=0).sum()# add group by here
dfB.groupby(level=0).sum()
idx=list(set(dfA.index).union(dfB.index))
dfA=dfA.reindex(idx).sort_index(ascending=False).bfill()
dfB=dfB.reindex(idx).sort_index(ascending=False).bfill()
dfA+dfB

Out[25]:
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5 Beds | 4 Full Baths

36
Images

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Shelburne Point, a remarkable and totally private parcel with over 4000 of lake frontage has been divided into six outstanding waterfront land parcels. The 3 remaining lots are covered by protective covenants. Each parcel has all utilities in place. This 13.3 acre lot is mostly open fields with expansive westerly views of the Adirondack Mountains and 847 feet of shoreline.

$2,950,000

Shelburne Point, a remarkable and totally private 89-acre parcel with over 4000 of lake frontage has been divided into six outstanding waterfront land parcels. The 3 remaining lots are covered by protective covenants. Each parcel has all utilities in place. This 18.7 acre lot has open fields on the western side with various pockets of trees providing privacy, elevation and


4,000' ft. Vermont vernacular home was constructed in 2005 to take advantage of its spectacular setting. Light fills this 3 bedroom, 3 bath home via wonderful window placement throughout to enjoy the beautiful views. The main living area features an open floor plan with radiant heat under the yellow birch floors. Upstairs has three bedrooms with mountain views, two baths, laundry and a large family room. The lower level is finished as a media room and exercise area also lined with windows. Outside is an in ground heated pool is surrounded with bluestone coping, a terrace with pergola, raised vegetable beds and a detached 1.5 story barn with workshop and office upstairs. Septic system capable of an additional 2 bedrooms.

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Very rare Shelburne Point waterfront building lot! Wonderful views of Lake Champlain and the Green Mtns with permitted clearing of trees. Over 450 feet of shoreline. Subject to a 1031 exchange. Subject to waterfront access by others.


virtual storage components.
Data compression is widely used to reduce the amount of data required to process, transmit, or store a given quantity of information. Data compression is the coding of data to minimize its representation. Compression can be used, for example, to reduce the storage requirements for files, to increase the communication rate over a channel, or to reduce redundancy prior to encryption for greater security.with DM type I; however, to our knowledge, there is only one recent study probing into DM type II drawing up on three-dimensional strain and strain rate.

The objectives of the present study were to evaluate the RV systolic and diastolic functions using conventional echocardiography, tissue Doppler imaging (TDI), and deformation indices (strain and strain rate) in patients with DM type II and without coronary artery disease or LV dysfunction.

Methods
=======

The study group was comprised of 22 diabetic patients (9 men and 13 women) aged 55.6 ± 6.0 years. These patients either referred to the DM Clinic of Rajaei Cardiovascular, Medical and Research Center or were amongst the hospital stuff. The control group consisted of 22 healthy individuals (9 men and 13 women). All the diabetic patients enrolled in this


and HbA1c were observed periodically and controlled by the endocrinologist in the aforementioned clinic. None of the patients had such diabetic complications as progressive and complex diabetic retinopathy, neuropathy, and nephropathy.

The study participants in the two groups underwent echocardiographic examinations (Vivid 7, GE Vingmed). The variables measured are presented as follows: The RV dimension and tricuspid annular plane systolic excursion (TAPSE) were measured from the apical four-chamber view.The RV Doppler parameters of the diastolic function (peak early \[A\] and peak late diastolic flow velocity \[E\], together with their ratio \[E/A\] and deceleration time \[DT\]) were recorded. The trans-tricuspid flow was measured in the apical four-chamber view using pulsed Doppler, with the sample volume positioned at the tips of the tricuspid leaflets. The measurements were averaged from three end-expiratoryto which the RV basal segment Sm, Em, Am, and E/Em (12 ± 1.9 cm/sec vs. 13.4 ± 2.1 cm/sec, 8.5 ± 2.1 cm/sec vs. 11.6 ± 2.4 cm/sec, 12.6 ± 2.7 cm/sec vs. 14.7 ± 3.3 cm/sec, and 0.05 ± 0.01 vs. 0.04 ± 0.01, respectively) were significantly lower in the case group than in the control group. There were no significant differences between the two groups with respect to the MPI of the RV and the acceleration time of the IVCT.

The data on the deformation indices of the two study groups are demonstrated in [Table 4](#t4-jthc-7-177){ref-type="table"}, according to which the RV basal segment systolic strain (€) and RV apical segment (€, SRs, and SRe) of the case group were significantly lower than those in the control


Us.

Ho. Lee. Shit.

Just further reminder of what I've always thought: if Milton had put a fifteen chapters at the beginning of Paradise Lost where he delved into Lucifer's bed wetting problems, it would have been way scarrier.Dozens of the European Union’s trading partners from South Africa to South Korea could impose tariffs on British exports next year, experts have warned.

About 70 countries holding EU free-trade agreements may refuse to recognise the UK as a member state from next March, according to lawyers.

The EU pledged to “notify” trading partners that Britain should be treated as a member during the 21-month transition period after it leaves the EU, but it cannot force such countries to do so.

As Britain will remain inside the EU customs union until December 2020, it is obliged to maintain duty-free trade on imports from the EU’s free-trade agreement partners. City lawyers believe that the same countries may decline to treat Britain as an EU member after


in for whichever beta tests you’ve previously selected, and you can change these selections on your Beta Profile page at any time.

Having current system specifications and checking the franchise boxes to express interest in beta testing our future products does not guarantee your entry into the beta test. We will grant a very limited number of people entry from the entire pool of those interested, based on their system specifications and other factors. While having an official Battle.net Beta Profile is one way to potentially get in, we’ll have information on other ways to increase your chances as we draw closer to the beta test.

Blue Posts

Originally Posted by Blizzard Entertainment

Lack of Blue Posts / "Where are the Blues?"
The whole team is here today. We're actively reading the forumsbonus is incorporated into its stat weight. So someone wearing 5 pieces of tier from a dungeon would be better off with at least one of them being swapped out for a raid drop.

Finally, I don't need 'the best raid gear' - I never said "HEROIC RAID TIER". I said Tier Set. that's it.

And why? Because it's my goal in the game to collect an armor set. Humor me, what set is there for a casual to complete? You say tier 11? I tell you NOPE, blizzard left the token requirements on, aka Nef or cho. I do not raid; I do not enjoy raids. in WotLK, I could, slowly but surely, obtain the tier set over a long period of time. by the time I was celebrating


raid if you want your tier gear" No. I'd rather unsub than be forced to do things I don't enjoy. That sub money can go to another game like League of Legends or something else. I'll say it again, clearer this time: I will not be forced by a GAME that required a MONTHLY FEE to do something I DO NOT FIND FUN to enjoy said game. Its a waste of money. And its funny, because you can argue your "tier should be raiders only derp derp" point on the forums all you want. I've spoken with my wallet. So have nearly a million others. Guess what blizzard is going to listen to? I'll give you a hint: It isn't the people on the forums, its the peoplefor the last tier saved it. Most of you won't remember this but BC was launched with 2 full tiers and 1 1/2 tier intact and recieved the second half of Tier 6 in 4 months. 4 Months, 3 complete tiers. Blizzard will never do this again because they're so bogged down by the weight of their own bureaucratic bulk and the fact that they can put out two horribly mangled half tiers and you'll still kiss their rears and call it gold.

Rome isn't burning. It's burnt.

WoW isn't dying. It's dead.

And if you can't smell the smoldering cinders anymore, it's because you've been inhaling for far too long.

As far as i can see Rome is still standing and has a population of 2.7 million residents. Its also the


subscribers. Unless Blizz goes out of it's way to do something that will make sence of WoW progression and PvP again.

As far as i can see Rome is still standing and has a population of 2.7 million residents. Its also the capital of Italy.

What i dont understand is how can you call a game with 10 million + gamers dead? I mean if you were talking about Guild Wars, AoC or WAR then yeah but WoW?

Since when does volume have anything to do with quality? 10 million people standing in strip mine doesn't change the fact that THEY'RE STANDING IN A STRIP MINE.

And it isn't 10 million gamers. Over 50% of asian players have multiple accounts. Maximum estimates put the number of worldwide players at under 8 million.stomach cancer. Research has linked Iodine deficiency with ADHD and Autism with rates rising dramatically over the last two decades. According to research in the USA Iodine levels have dropped by more than half since the 1970’s. Under production of the hormone thyroxine causes weakened neural connections in the brain/nervous system. Iodine is therefore especially necessary for pregnant women and the development of their babies.

From about the 1920’s onwards many people were suffering the effects of iodine deficiency, sometimes developing a visible swelling at the front of the neck called a Goiter in adults and preventable mental retardation in children due to low levels of iodine in the soil and diet. Governments recognised the problem and decided to add iodine to table salt as a way of increasing


Berkshire's Indian Summer hopes on hold as storms rage in the Atlantic

Hurricanes in the Atlantic have lead to a change in the weather

11 September 2018

There could still be an Indian Summer but we might have to wait. Credit:getreading

By Brett Gibbons

Hopes of an Indian Summer across Berkshire appear to have been put on hold with disturbances in the Atlantic bringing more unsettled conditions.

Initial predictions suggested a mild, settled start to September with balmy temperatures and plenty of sunshine.

But the best of the weather may now not arrive until the end of the month and last into early October.

Although temperatures reached 25C in the south east on Sunday, September 9 and are forecast to hit 23C in Reading, Berkshire on Tuesday, September 11 it is likely to start to feelblocks, I fully expect my offspring to be playing Blosics 59 on some sort of holographic RFID controlled computablet in the foreseeable future.

when i was talking to my dearest cousin one day he admitted he had a huge fear of hippopotamuses especially albino ones which made me wanna take him to the zoo and force him to make friends with david the albino hippopotamus who is just about the friendliest hippopotamus that ever walked the earth but he replied that would be too much for him and kicked me in the

I have noted the complaints about a lack of shooting games lately. Rest assured I am always listening to your bitching cries for justice, so today’s game has plenty of shooting (and keyboard controls that will molest your


whining brain through the eye sockets until you get the urge to chop off your disobedient fingers).

Little Known Fact: my grandfather was actually a Supermarine Spitfire pilot during WW2. Unfortunately he was dishonorably discharged for reasons that are still unclear to me. Maybe getting drunk on homemade scotch and wing-surfing naked during combat was frowned upon by the RAF?

You know, I like this game, but the only problem is that its logic really doesn’t conform with what my brain tells me. How does woman + lust not equal Kelly Brook? And how does gluttony + chaos not make the Bellagio Buffet in Vegas?

The latest opinion polls show that most of you fruitcakes want to be exactly like your beloved Admin: winner of the Nobel Prize in 4 categories,inches from your face. For I am Angry Husky, and I am not without mercy.

Although you might not expect an accomplished neurosurgeon to have the rugged qualities associated with a bona fide “Mountain Man”, I am proud to say that I am often confused with one none the less. It could be the beard, it could be the long hair, or maybe it’s just the groundhog skin loincloth.

If I could play god and reinvent the world from scratch I have to admit I wouldn’t do much differently. I would however forgo the giant armored sea spiders in favor of something a little more useful, like say a mix between a puppy and a vending machine.

Jump Mr. Frog…! Fly Mr. Bird…! Run Mr. Dog…! Act like you like me


you guys to obsess over. And don’t forget – all of our HTML5 games are playable on high-end mobile phones and tablets!

Merry Christmas Fruitcakes! As my present to you here’s a set of achievements and a leaderboard for our new html5 game Vector Runner Remix. It might not be the greatest present, but it sure beats what I got from my parents: 12-pack of tube socks and a nice big portion of when-I-was-your-age lectures.

I have this reoccurring nightmare where I’m a college freshman being chased by a middle aged lady who reeks of kiwi-strawberry flavored MD 20/20. I cant quite understand what she’s yelling, but it contains the words alabaster glutes. Actually, that might be a memory.

If I only had 10 bullets I would probably use the firstour freedom dammit.

I haven’t molested my spacebar this much since my nerds ‘r’ usawesome & popular club at University organized a Press The Spacebar competition. As the winner of the sliver medal I got a brand new 56k modem beer keg.

I know you guys were looking forward to the latest Hannah Montana Kissing Cousins game, but you’re going to have to settle for this new DYOG exclusive instead. If you want a mental picture of this beast, imagine Vector Runner mixed with Dolphin Olympics, but with more vectors and an extra serving of dolphinsexualassault.

Wonderputt reminds me of Wünderputz – something you can ask for in any respectable German “massage parlor”. Just don’t be surprised when a “masseuse” walks in holding a 3 foot homemade knackwurst sausage, accompanied by


have to decide on your own. By taking mountains of drugs. And seeing if they make you feel awesome or not.

I’m still not sold on this whole gravity business. I know a while back we determined that gravity makes pooping more pleasant, but beyond that I’m still not seeing many positives. In my version of heaven I’m just floating around town in my underwear. Oh, and don’t forget about the puppies. There are floating puppies everywhere.

It’s common knowledge to those of us in the science community that spiders (known to the more educated as arachnids), are actually the direct descendants of giant lizards, monsters, the devil, Stephen King, and cats.

In celebration of the new school year, today’s game is all about arithmetic. And don’t you dare think ofa screen full of balls, but after all these years there is not a single joke left in the great Encyclopedia Balltanica. I am in desperate need of some new material! Maybe someone could create a game where you have to strangle chickens? Or punish a naughty monkey…

Ever since the beginning of THE WAR ON TERROR, one has to be very careful about using the B-word in public. You know what I’m talking about, right? The B-thing that does the e-thing? Yeah? The… you know… a… *cough* bomb *cough* So anyways, this game OH GOD THEY’VE FOUND ME PLEASE I’M A WEBMASTER NOT A TERRORI-

It’s almost not fair for me to put up 3D avoider games, since this is the birthplace of the shining light in all our


or anything. I just heard about it from some friends who were there. Friends who aren’t Furries. Friends of friends, actually. I’m completely hairless truth be told.

Fear not, citizens of Earth! When goofy galactic robots invade, you will be there to fight off the invasion. The government has surgically removed your skeleton to provide you with greater agility, and attached powerful automatic weapons to your hands for combat (they are also auditing you for the 2006 tax year to increase your aggression).

That’s right folks. It’s time for another Dig Your Own Grave exclusive game. I know! It’s totally crazy. We’re pooping these things out like we just ate them for breakfast. This game features some old-skool 3D vector graphics, and a pace so fast that we can actuallygonna grab some lunch first; haven’t eaten all day mon amigo!”

If right now you have the option of trying this game or instead heading to the bathroom and smoking a giant brick of crack cocaine, I would highly recommend that sweet, sweet crack cocaine. It’s scientifically proven to be less addictive, and who needs teeth anyways?

Mondays… Now I don’t want to be at work any more than you do, but there are easier ways to get fired. So put your pants back on and let’s do it the right way by playing flying hamster games on the company dime. This one is a lot like Kitten Cannon, only it’s a little less random because you can use your mouse to control how the hamster glides.

We haven’t done a


this one is to build up points by doing combos. Using your mouse you can lock onto multiple targets at once and blow them to bits with a single shot. The more points you get, the longer the game lasts.

Do you hate one-eyed one-horned monsters? Me too! Let’s smash their heads with a hammer. This game may seem easy at first, but it starts messing with you after a while… trust me. And if the game doesn’t seem easy at first, it’s because you’re playing it with the number keys at the top of the keyboard and not the ones on the number-pad silly!

Help the poor little boneless man avoid the metal spikes raining down from the sky! I was able to dodge 135. Coincidentally that is theclinical differences among PJP between industrialized and developing countries were expected to be found, studies carried out in limited resource settings were not considered for this analysis. Studies that included exclusively non-HIV patients were also excluded. Studies with both HIV and non-HIV-infected population were included only if data of HIV-infected patients could be analyzed separately. Studies were required to have at least 20 PJP cases. Moreover, those studies that included exclusively patients admitted to intensive care units (ICU) were also excluded to avoid a severity bias.

3. RESULTS
==========

3.1. Baseline Characteristics
-----------------------------

One hundred thirty-six HIV-infected patients were diagnosed with PJP between January 2000 and December 2013. There were 94 (69.1%) males and 42 (30.9%) women with a mean age of 41 (±10) years. Fifty percent of them had not been previously


48% on 2000 to 67% in 2013 (*P* = 0.54) (Figure [1](#F1){ref-type="fig"}C). PJP preceded HIV diagnosis more frequently in patients \>50 years old (87% vs 62%, *P* \< 0.001).

![(A) Yearly evolution of annual incidence, (B) median age of the patients at diagnosis, and (C) proportion of patients with unknown HIV infection prior to the PJP episode. HIV = human immunodeficiency virus, PJP = *Pneumocystis jirovecii* pneumonia.](medi-94-e681-g002){#F1}

3.3. Clinical Data and Diagnosis
--------------------------------

Clinical and diagnosis-related characteristics of PJP episodes are shown in Table [2](#T2){ref-type="table"}. The mean average time of symptoms before the patient attended in to the hospital was 22 (±23) days. One hundred eight (79%) patients underwent FBS. Ninety-eight (72%) episodes were considered definite diagnoses of PJP and 38 (28%) were considered probable diagnoses according to the definitions stated earlier. No differences between patientsBy title and abstract review, 660 articles were excluded on the grounds of being single-case reports, reviews, or guidelines, or having a focus other than HIV-infected patients. From the remaining 63 studies, 45 were excluded for additional causes after full-text reading (Figure [3](#F3){ref-type="fig"}). The key studies addressing PJP in the developed world are summarized in Table [4](#T4){ref-type="table"}.

![Flow chart of search strategy for article selection. ICU = intensive care unit.](medi-94-e681-g006){#F3}

######

Summary of Selected Studies on PJP in HIV-Infected Patients in Developed Settings During the HAART Era

![](medi-94-e681-g007)

Only 3 studies included information about the evolution of the incidence of PJP and in all 3, a negative trend can be observed throughout the years. A study based on patients from the National Health Service in England reported a decrease in the incidence


= 0; i < count; i++) {
				BTextWidget* widget = fWidgetList.ItemAt(i);
				BColumn* column = poseView->ColumnFor(widget->AttrHash());
				if (column != NULL
					&& strcmp(column->AttrName(), attrName) == 0) {
					widget->CheckAndUpdate(poseLoc, column, poseView, visible);
					break;
				}
			}
		}
	} else {
		// no attr name means check all widgets for stat info changes

		// pick up stat changes
		if (resolvedModel && resolvedModel->StatChanged()) {
			if (resolvedModel->InitCheck() != B_OK)
				return;

			if (visible)
				UpdateIcon(poseLoc, poseView);
		}

		// distribute stat changes
		for (int32 index = 0; ; index++) {
			BColumn* column = poseView->ColumnAt(index);
			if (column == NULL)
				break;

			if (column->StatField()) {
				BTextWidget* widget = WidgetFor(column->AttrHash());
				if (widget != NULL)
					widget->CheckAndUpdate(poseLoc, column, poseView, visible);
			}
		}
	}
}

bool
BPose::_PeriodicUpdateCallback(BPose* pose, void* cookie)
{
	return pose->UpdateVolumeSpaceBar((BVolume*)cookie);
}

bool
BPose::UpdateVolumeSpaceBar(BVolume* volume)
{
	bool enabled = TrackerSettings().ShowVolumeSpaceBar();
	if (!enabled) {
		if (fPercent == -1)
			return false;

		fPercent = -1;
		return true;
	}

	int32 percent = CalcFreeSpace(volume);
	if (fPercent != percent) {
		if (percent > 100)
			fPercent = 100;
		else
			fPercent = percent;

		return true;
	}

	return false;
}

void
BPose::UpdateIcon(BPoint poseLoc, BPoseView* poseView)
{
	IconCache::sIconCache->IconChanged(ResolvedModel());

	int32 iconSize = poseView->IconSizeInt();

	BRect rect;
	if (poseView->ViewMode() == kListMode) {
		rect = CalcRect(poseLoc, poseView);
		rect.left += kListOffset;
		rect.right = rect.leftup setting up huge tables on
disk, and doing interpolation.

My 64 atom supercells would take, initially a week of runtime to get 100
timesteps. After a few years, my SGI R8000 could do that calc about 90 seconds
per time step. 10 years after I finished up, my home computer could do 10s
wall clock per time step. I've not tried it recently, could be fun.

Dirac eqn is a harder thing to deal with in general. We used Schrodinger eqn
parameterized for soft pseudopotentials. Also had a restriction on how many
k-points we could handle, and ionization was sadly impossible in the code, as
the repeated volume of supercells made any unbalanced charge effectively
infinite. I came up with some ways to handle this, but we lacked computer
power for that. Likely it would work today.

Honestly, I


miss that work. It was fun.

~~~
plus
> ionization was sadly impossible in the code, as the repeated volume of
> supercells made any unbalanced charge effectively infinite. I came up with
> some ways to handle this, but we lacked computer power for that.

Calculations of charged periodic systems are possible through the use of Ewald
summation techniques (or particle mesh Ewald/related techniques). It basically
introduces a homogeneous neutralizing background charge, which is unphysical
and makes it so that a the total energy of a charged particle in a box
converges to the "true" result as a function of 1/volume. This is applicable
to both classical and quantum simulations.

There is no way to do a "true" charged periodic system, but honestly that's
never what you want (because true infinite systems with net charge don't
exist!). You can do betterChapter 630, Acts of 1964, p. 933.
The Authority has adopted a mass transit than for the Zone.  It proposes to construct a combination subway and surface rapid rail system, 97.7 miles in length, with stations to serve the most densely populated areas of the Zone.
The estimated cost of constructing the transit system is $2,494,600,000. Funds are to be obtained from the following sources:  The Authority will issue tax-exempt gross revenue bonds in the amount of $835,000,000; the federal government will contribute $1,147,044,000; and political subdivisions in the Zone will contribute the sum of $573,522,000. [4]  Of this amount, $149,900,000 will come from political subdivisions in Virginia. [5]  The shares of the County and City are $61,900,000 and $800,000, respectively.  The County and City