secretion in the uTHP-1 or dTHP-1 cells, while U0126 and SP600125 significantly decreased MMP-9 secretion, both in the absence or presence of CypA. Similar results were observed in NF-κB activity by IF. The data shown are representative of similar results from three independent experiments.](ken225f7){#F7}

Ca^2+^ mobilization and cell adhesion in the THP-1 cells with CypA stimulation
------------------------------------------------------------------------------

To observe CypA\'s influence on Ca^2+^ mobilization and cell adhesion in THP-1 cells, we used laser scanning confocal fluorescence microscope and adhesion assay. After the addition of CypA, Ca^2+^ mobilization in the uTHP-1 and dTHP-1 cells was increased ([Fig. 8](#F8){ref-type="fig"}a). Anti-CD147 antibody HAb18 strongly decreased cytosolic Ca^2+^ concentration and CypA had no effect on Ca^2+^ concentration after HAb18 treatment. When CypA was pre-incubated with CSA or cells were pre-incubated with HAb18, no cytosolic Ca^2+^cyclophilin-mediated signalling events for the adhesion of monocytes/macrophages to ECM. CSA in this study blocked CypA-induced adhesion by interrupting the CypA-binding to CD147. These results suggested that CypA promotes adhesion of monocytes/macrophages to ECM by direct binding to CD147, and also suggested that during the progress of RA, CypA might enhance the adhesive and invasive abilities of monocytes/macrophages to synovium or cartilage and contribute to the joints' impairment.

In conclusion, our findings indicate that CypA enhances the adhesion of monocytes/macrophages to ECM in RA, and up-regulates MMP-9\'s expression and potential invasion in monocytes/macrophages to degrade cartilage by direct binding to CD147 which enhances the calcium mobilization and NF-κB activity. These results suggest the potential role of cyclophilin--CD147 interactions in RA pathogenesis and may serve as a preliminary foundation for


_GLIBCXX_BIND_V_ARGS _Mu<_T1>()(_M_arg1, ::std::tr1::tie(_GLIBCXX_BIND_ARGS)), _Mu<_T2>()(_M_arg2, ::std::tr1::tie(_GLIBCXX_BIND_ARGS)), _Mu<_T3>()(_M_arg3, ::std::tr1::tie(_GLIBCXX_BIND_ARGS)), _Mu<_T4>()(_M_arg4, ::std::tr1::tie(_GLIBCXX_BIND_ARGS)), _Mu<_T5>()(_M_arg5, ::std::tr1::tie(_GLIBCXX_BIND_ARGS))
#define _GLIBCXX_TUPLE_ADD_CREF typename __add_c_ref<_T1>::type __a1, typename __add_c_ref<_T2>::type __a2, typename __add_c_ref<_T3>::type __a3, typename __add_c_ref<_T4>::type __a4, typename __add_c_ref<_T5>::type __a5
#define _GLIBCXX_TUPLE_COPY_INIT _M_arg1(__in._M_arg1), _M_arg2(__in._M_arg2), _M_arg3(__in._M_arg3), _M_arg4(__in._M_arg4), _M_arg5(__in._M_arg5)
#define _GLIBCXX_TUPLE_ASSIGN _M_arg1 = __in._M_arg1; _M_arg2 = __in._M_arg2; _M_arg3 = __in._M_arg3; _M_arg4 = __in._M_arg4; _M_arg5 = __in._M_arg5;
#define _GLIBCXX_TEMPLATE_PARAMS_NULL_CLASS typename _T1 = _NullClass, typename _T2 = _NullClass, typename _T3 = _NullClass, typename _T4 = _NullClass, typename _T5 = _NullClass
#define _GLIBCXX_TEMPLATE_ARGS_STRIPPED typename __strip_reference_wrapper<_T1>::__type, typename __strip_reference_wrapper<_T2>::__type, typename __strip_reference_wrapper<_T3>::__type, typename __strip_reference_wrapper<_T4>::__type, typename __strip_reference_wrapper<_T5>::__type
#define _GLIBCXX_TEMPLATE_PARAMS_U typename _U1, typename _U2, typename _U3, typename _U4, typename _U5
#define _GLIBCXX_TEMPLATE_ARGS_U _U1, _U2, _U3, _U4, _U5
#define _GLIBCXX_REF_WRAP_PARAMS ref(__a1), ref(__a2), ref(__a3), ref(__a4), ref(__a5)
#define _GLIBCXX_REF_TEMPLATE_ARGS _T1&, _T2&, _T3&, _T4&, _T5&
#define _GLIBCXX_NUM_ARGS_PLUS_1 6
#define _GLIBCXX_T_NUM_ARGS_PLUS_1 _T6
#include _GLIBCXX_REPEAT_HEADER
#undef _GLIBCXX_T_NUM_ARGS_PLUS_1
#undef _GLIBCXX_NUM_ARGS_PLUS_1
#undef _GLIBCXX_REF_TEMPLATE_ARGS
#undef _GLIBCXX_REF_WRAP_PARAMS
#undef _GLIBCXX_TEMPLATE_ARGS_U
#undef _GLIBCXX_TEMPLATE_PARAMS_U
#undef _GLIBCXX_TEMPLATE_ARGS_STRIPPED
#undef _GLIBCXX_TEMPLATE_PARAMS_NULL_CLASS
#undef _GLIBCXX_TUPLE_ASSIGN
#undef _GLIBCXX_TUPLE_COPY_INIT
#undef _GLIBCXX_TUPLE_ADD_CREF
#undef _GLIBCXX_BIND_V_ARGS
#undef _GLIBCXX_BIND_V_TEMPLATE_ARGS
#undef_M_arg7(__in._M_arg7), _M_arg8(__in._M_arg8), _M_arg9(__in._M_arg9), _M_arg10(__in._M_arg10)
#define _GLIBCXX_TUPLE_ASSIGN _M_arg1 = __in._M_arg1; _M_arg2 = __in._M_arg2; _M_arg3 = __in._M_arg3; _M_arg4 = __in._M_arg4; _M_arg5 = __in._M_arg5; _M_arg6 = __in._M_arg6; _M_arg7 = __in._M_arg7; _M_arg8 = __in._M_arg8; _M_arg9 = __in._M_arg9; _M_arg10 = __in._M_arg10;
#define _GLIBCXX_TEMPLATE_PARAMS_NULL_CLASS typename _T1 = _NullClass, typename _T2 = _NullClass, typename _T3 = _NullClass, typename _T4 = _NullClass, typename _T5 = _NullClass, typename _T6 = _NullClass, typename _T7 = _NullClass, typename _T8 = _NullClass, typename _T9 = _NullClass, typename _T10 = _NullClass
#define _GLIBCXX_TEMPLATE_ARGS_STRIPPED typename __strip_reference_wrapper<_T1>::__type, typename __strip_reference_wrapper<_T2>::__type, typename __strip_reference_wrapper<_T3>::__type, typename __strip_reference_wrapper<_T4>::__type, typename __strip_reference_wrapper<_T5>::__type, typename __strip_reference_wrapper<_T6>::__type, typename __strip_reference_wrapper<_T7>::__type, typename __strip_reference_wrapper<_T8>::__type, typename __strip_reference_wrapper<_T9>::__type, typename __strip_reference_wrapper<_T10>::__type
#define _GLIBCXX_TEMPLATE_PARAMS_U typename _U1, typename _U2, typename _U3, typename _U4, typename _U5, typename _U6, typename _U7, typename _U8, typename _U9, typename _U10
#define _GLIBCXX_TEMPLATE_ARGS_U _U1, _U2, _U3, _U4, _U5, _U6, _U7, _U8, _U9,


with substantially lower velocity. Generally, the restricted nucleophile specificity of the enzyme for glycine and hydrophilic amino acid residues in P1' position, as well as numerous side reactions, limit the utilization of subtilisin in peptide synthesis, especially in the case of the segment condensations. Contrary to the published data, we have proved that proline derivatives were not acylated in any media with the help of subtilisin Carlsberg. Effective ester hydrolysis of a protected nonapeptide corresponding to the N-terminal sequence of dicarba-eel-calcitonin catalysed by subtilisin was achieved.work a little harder to get the diverse cast that you want.

Daniel: It’s hard to address a large systemic issue when you only have control over one part. We have this one little slice we can play in, and we have the influence and do the things we can do, and we can have make some decisions about our project, it’s just a drop in a bucket. That said, I do think that drops are how buckets get filled up.

Ty: You do what you can do with the access and influence you have, and you hope that you’re making things better by at least a little bit. If enough people do that, then things will get better.

In Season 1 you made same noticeable changes, like bringing Chrisjen Avasarala


‘Mermaid’ demo,” editor Steven Tweedie later told my colleague Casey Newton on Twitter. Beyond that, it’s a mystery.

One might interpret this news to mean that Magic Leap actually is having problems creating holograms that can stand up to scrutiny, or that it’s still in an early stage of developing compelling hardware and software. But maybe Beyoncé has just been too busy taking over the internet (and possibly the world) to bother with anything less.many BatchWriteItem requests as you want at one time. Assuming you've provisioned enough write throughput, you should be able to speed things up significantly by splitting those 20k rows between multiple threads/processes/hosts and pushing them to the database in parallel.
It's maybe a bit heavyweight for that small of a dataset, but you can use AWS Data Pipeline to ingest data from S3. It basically automates the process of creating a Hadoop cluster to suck down your data from S3 and send it to DynamoDB in a bunch of parallel BatchWriteItem requests.


job on Tuesday warned Johnson of “challenging times ahead”.

Ursula von der Leyen, the German conservative set to take over at the helm of the European Commission from November, also said that all parties had a “duty to deliver something which is good for people in Europe and the United Kingdom”.

Johnson wants to scrap the so-called “Irish backstop”, an insurance policy written into the Brexit withdrawal deal to maintain an open border for economic and security reasons between the Republic of Ireland and Northern Ireland, a constituent of the UK, until a new British-EU trade deal is reached.

Those in favour of Brexit fear the backstop could trap Britain in EU trading rules indefinitely and prevent the UK from striking trade deals with countries around the world, given that a1. Introduction {#sec1-sensors-20-03823}
===============

The multi-scale representation of spatial data is a classic topic in cartography that requires many generalization operations, such as simplification, aggregation, typification, and displacement \[[@B1-sensors-20-03823],[@B2-sensors-20-03823],[@B3-sensors-20-03823],[@B4-sensors-20-03823],[@B5-sensors-20-03823],[@B6-sensors-20-03823]\], to be realized. Water is necessary for economic, social, and environmentally sustainable development. For the multi-scale representation of water areas, generalization operations such as the selection of objects, the simplification of boundaries, and the aggregation of multiple objects are usually applied, which leads to changes in water areas in terms of the quantity, shape, and distribution. To solve the quality problem of multi-scale maps, a change detection method can usually be applied.

Change detection refers to the process of identifying differences through a comparative analysis of the state of the same geographic entity acquired from images or databases in different periods \[[@B7-sensors-20-03823]\],


areas, and black represents the negative change of water areas. Compared with the traditional map overlay method, two advantages of the proposed method should be addressed. (1) As shown in [Figure 10](#sensors-20-03823-f010){ref-type="fig"}, the proposed method can effectively detect many different types of changes, such as morphology change, hole change, and derivative change, while the traditional map overlay method can only divide the changes into two types, namely, positive and negative changes, as shown in the black box. (2) As shown in [Figure 11](#sensors-20-03823-f011){ref-type="fig"} in the next subsection, the changes of water areas can be hierarchically expressed, which enables the reader to progressively acquire change information at different levels of detail, while the traditional map overlay method cannot achieve this.

2.  Hierarchical expression of change

In turn, a water areaQ:

Classes & Defines in Puppet

Although I know the immediate solution to a problem I was facing yesterday (thanks to the folks over at IRC #puppet), I still don't understand how it solved the problem, or rather what's the fundamental difference between classes and defines in this particular scenario:
The original define, which was incorrect:
define srv($name,$enable="true",$ensure="running",$provider="runit",$hasstatus="true",$hasrestart="true"){

                exec {"sleep 5": path=>"/usr/bin:/usr/sbin:/bin:/sbin", before=>Service["$name"],}

                service{"$name":

                    enable=>$enable,


Its hard to study surroundings if you are running from a monster ...

As dreams are symbolic, if ones life is going quite smoothly and there is nothing really distressing someone, they shouldnt be get nightmares. Nightmares will come when someone has life issues.

dreamerinmiami wrote:This may sound weird but I want to have nightmares. I want to have nightmares because I believe it would be easier to become lucid. I cant remember the last time I had a real nightmare. I have noticed that I become lucid when crazy things happen or when I feel very overwhelmed in dreams. and those are rare. most of my dreams are pretty normal. like everyday things...... maybe feeling very scared in a dream will help out lol

http://www.world-of-lucid-dreaming.com/forum/viewtopic.php?t=1037check it out, its about nightmaresin the United States or Canada evidencing its asserted interest in the Parts.
The Trustee moved for summary judgment on all issues raised by ATG's Complaint. Stanchart moved for summary judgment on ATG's Complaint and the Trustee's cross-claim against it.

DISCUSSION
The first issue is whether the Court should apply Ontario law or Georgia law in this proceeding. When a bankruptcy court considers an issue that is not addressed by federal law and does not implicate compelling federal interests, it is appropriate for the court to apply the choice of law rules of the state in which it sits to determine the applicable substantive law.[2]Bi-Rite Enterprises, Inc. v. Bruce Miner Co., Inc., 757 F.2d 440, 442 (1st Cir.1985); Compliance Marine, Inc. v. Campbell (In re Merritt Dredging Co., Inc.), 839 F.2d


Security Agreements and the financing statements filed by the Secured Creditors and concludes that Stanchart has a perfected security interest in the Parts.
ATG asserts that it has a consignor's interest in the Parts. Unlike issues involving perfection of a security interest, the validity and effect of a consignment agreement is not governed by any of the exceptions enumerated in O.C.G.A. § 11-1-105(2). Rather, the general choice of law provision of the U.C.C., O.C.G.A. § 11-1-105(1), is used to determine the applicable substantive law. As stated previously, O.C.G.A. § 11-1-105(1) provides that parties to a transaction may provide that the law of any jurisdiction will govern their rights under their agreement as long as the jurisdiction bears a reasonable relationship to their transaction. The Consignment Agreement states that itshowed a robust effect of mask contrast on suppression durations, and an effect of mask size that depended on collinearity. Specifically, higher mask contrasts produced longer suppression regardless of collinearity and mask size. Mask size, on the other hand, had little effect on suppression when collinearity was low and it weakened suppression when collinearity is high. These observations parallel prior findings in BR, further substantiating the close link between the two paradigms and demonstrating the usefulness of a shared explanatory framework describing both phenomena.


may impose limitations as to the weight, size or use thereof, on designated highways, which prohibitions and limitations shall be designated by appropriate signs placed on such highways. Suitable and convenient routes shall be provided for traffic so diverted and appropriately marked.
[4]  Officers are prohibited from directly or indirectly recommending the employment of any particular attorney, bailbondsman, or wrecker service.
[5]  See generally Vail v. Board of Education, 706 F.2d 1435 (7th Cir.1983): "[I]t is the binding nature of a contract rather than its length which is significant... [T]he length of time that an individual retains an asset affects the weight or value of the interest, but not the nature of the interest." Id. at 1438.
[6]  Though Bart v. Telford, 677 F.2d 622 (7th Cir.1982) concernedduring the course of infection. These results suggest the spread of infection to cells expressing different classes of polytropic viruses or an alteration in the expression of the endogenous proviruses in infected cells. Exogenous mouse retroviruses encode a glycosylated gag protein (gGag) originating from an alternate translation start site upstream of the methionine start site of the gag structural polyproteins. The functions of gGag remain unclear, but mutations that eliminate its synthesis severely impede in vivo replication of the virus with little effect on replication in fibroblastic cell lines. APOBEC3 proteins have evolved as innate defenses against retroviral infections. Both mice and humans express APOBEC3 proteins that have cytidine deaminase activity leading to hypermutation of viral transcripts and inactivation of infecting retroviruses. HIV encodes the VIF protein to


Shortly after Election Day eight years ago, Thomas V. “Mike” Miller, president of Maryland’s State Senate, said his just-won tenth term in the General Assembly would be his last. The then 63-year-old Democrat was worn out from tangling with Republican governor Robert Ehrlich and still haunted by criticism for having contacted judges ruling on a 2002 legislative redistricting plan. Miller soon thought better of stepping down. Announcing his 2014 run, he told reporters that his wife “would just as soon I was down here instead of bothering her.”

Larry Hogan, Maryland’s new Republican governor, may soon recognize the feeling. A newbie to elective office, he faces a rejuvenated Miller, who, backed by veto-proof Democratic majorities in the Senate and the House of Delegates, wields nearly untrammeled power. Some observerscall him the shadow governor.

“I’m not sure I would say ‘shadow,’” laughs Prince George’s County Executive Rushern L. Baker III.

Miller insists his leadership is bipartisan and laissez-faire. “I govern like a jockey on a horse,” he says. “I’m very loose on the reins.”

But he also knows how to get his way. In 2012, as legislators worked frantically to finish the state’s $37-billion budget, Miller forced an adjournment, unleashing a series of punishing automatic cuts. The maneuver impelled then governor Martin O’Malley to call two special legislative sessions to pass a budget and approve a casino to be built near Miller’s boyhood home in Prince George’s County (and close to his family’s food-and-beverage distributorship).

“He was down, flat out on the canvas,” recalls Brian Frosh, Maryland’s newly elected attorney general


sub-category*White British24,57455.2(ref)^d^  (ref)^d^  White Irish39260.01.221.04--1.43**.02**1.231.05--1.45**.01**Any other White background53958.31.140.99--1.30.061.141.00--1.31.05White & Black Caribbean3657.11.080.66--1.78.761.020.61--1.70.93White & Black African1655.21.000.48--2.07.990.940.45--1.98.88White & Asian3644.40.650.42--1.01.050.620.40--0.97**.04**Any other Mixed background3454.80.980.60--1.62.950.960.58--1.59.87Indian24052.80.910.75--1.09.290.890.74--1.08.25Pakistani11359.81.210.90--1.61.211.130.84--1.52.43Bangladeshi1840.00.540.30--0.98**.04**0.580.31--1.06.08Any other Asian background13166.21.591.18--2.13**.002**1.611.19--2.17**.002**Caribbean16448.70.770.62--0.95**.02**0.760.61--0.95**.02**African13353.60.940.73--1.20.610.870.67--1.13.30Any other Black background1753.10..920.46--1.84.810.930.46--1.89.85Chinese6145.90.680.49--0.96**.03**0.640.45--0.90**.01**Any other ethnic group4956.31.040.68--1.59.841.100.71--1.70.66Note: Significant associations (*p* \< .05) are highlighted in bold.^a^Adjusted for age, gender, long-standing condition, time since first treatment, tumour group, patient classification, response to treatment, IMD quintile, Trust location (in/outside Greater London) and Trust.^b^Analysis was restricted to 52,029 respondents and excluded patients who did not respond to Q17 (*n* = 5031) or had missing data for age, gender, ethnicity, time since first treatment, long-standing condition status, response to treatment or IMD quintile (*n* = 11,677). According to the likelihood ratio test, the model using ethnic sub-categories was significantly better (at 95% confidence level) than the model using broad categories (*χ* ^2^(10) = 28.77, *p* = .001).^c^For comparisons by broad ethnicother Black background1263.20.540.31--0.69**\<.001**0.690.26--1.79.44Chinese6059.40.460.31--0.69**\<.001**0.530.35--0.79**.002**Any other ethnic group4671.90.810.47--1.40.451.140.65--2.00.64Note: Significant associations (*p* \< .05) are highlighted in bold.^a^Adjusted for age, gender, long-standing condition, time since first treatment, tumour group, patient classification, response to treatment, IMD quintile, Trust location (in/outside Greater London) and Trust.^b^Analysis was restricted to 40,880 respondents and excluded patients who did not respond to Q24 (*n* = 18,931) or had missing data for age, gender, ethnicity, time since first treatment, long-standing condition status, response to treatment or IMD quintile (*n* = 8926). According to the likelihood ratio test, the model using ethnic sub-categories was not significantly better (at 95% confidence level) than the model using broad categories according to the likelihood ratio test (*χ* ^2^(10) = 12.80, *p* = .24).^c^For comparisons by broad ethnic categories, the reference group was White patients.^d^For comparisons by ethnic sub-categories, the reference


Partners

Scene Radio is both pleased and proud to be working with Pink Saltire (SCIO). Pink Saltire is a registered Scottish Charitable Incorporated Organisation (SCIO) and listed on the charity register held by the Scottish Charity Regulator (OSCR). We are a national equalities organisation, managed and run by LGBT+ people, established in[…]around a spoonful of Insalata Russa on a slice of bread from a French stick. Those of you who are of a certain age may remember Rosso Antico (a red aperitif) or a Cinzano (vermouth) or a martini. Sometimes it would be a straight gin with a twist of lemon. Today you may prefer a different aperitif like Aperol or a glass of Prosecco or a Campari – you get the idea!

It keeps well in the fridge and is an easy accompaniment for drinks – I am thinking of those unexpected guests who may pop in …. a drink, a small plate of Insalata Russa and some good bread. If my mother was still alive she would probably be making it on Christmas eve or Christmas day.

Insalata Russa


feed tube while the blender or processor is running, Before adding additional oil, ensure that the oil, which has previously been added has been incorporated completely.Add a tablespoon of fresh lemon juice when the mayonnaise is creamy. If you are not making the traditional Italian version, it is common to add vinegar instead of lemon juice and a teaspoon of Dijon mustard.As an alternative, the Spaniards like to add a little saffron (pre-softened in a little warm water). Add this once the mayonnaise is made.

This very simple salad was popular as an antipasto or a light meal when I was growing up as child in Trieste. In the Triestian dialect this salad is called Insalata di tonno, fazoi, zivola e radiccio.

Trieste is in North Eastern Italy not faronce belonged to the Austrian- Hungarian empire, the pastry in a Triestine strudel is not as thin and therefore easier to roll.

Autumn is a good time for apple desserts and I was asked recently about suitable food to take on a picnic. This apple strudel is nice to eat hot or cold and the pastry does not go soggy.

With Easter coming up and apples been so abundant, a Strucolo de pomi could be the go.

I have written about Strucolo before and as a child it was my job to prepare the apples. Here is the link to the recipe:

My friend called them Vanille Kipferl, I recognised them instantly as Chifeletti (‘ch’ sound is pronounced as k in Italian and ‘letti’ at the end of words in Italian means


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Octobermissing his first recovering from an ACL tear. The 49ers bulked him up to near 300 pounds to play along the interior in a 3-4, where he was clearly out of place his first two seasons.

The Florida State alum in 2016 converted to outside linebacker, dropping some 25 pounds, where he was asked to rush from the edges like he did in college. The only problem: That position also required dropping into pass coverage, where Carradine was also out of his element.

Now the 49ers are running a 4-3 for the first time since Dennis Erickson was head coach in 2004. And Carradine appears to fit well. He’s unsigned beyond the season and seems motivated to have a big campaign.

But he’ll have to stand out among a crowded group.


dictated by presidential politics. And history suggests it is becoming increasingly difficult for Senate candidates to separate their fates from the top of the ticket.

AD

In 2016, not a single state gave its presidential electoral votes and its Senate seat to candidates of different parties after six states did so in 2008 and five states did in 2012. Incumbents still generally tend to enjoy an advantage over the top of the ticket, but strategists and political scientists see that trend fading.

AD

The question for 2020 Senate races could be whether the presidential electoral map remains fairly close to the 2016 results — where Trump wins or a Democrat prevails with a few states such as Michigan, Pennsylvania and Wisconsin deciding the final outcome — or whether a landslide scenario opensfirst three months of 2019. He said in a brief interview this week that he was prepared whether Abrams runs and suggested he was ready to paint any opponent as too liberal for the state.

“Regardless of who they put up, that person, if they were to end up in the Senate, would be nothing but a rubber stamp for this left-wing radical proposition that is being put forth right now,” he said. “And I can tell you . . . the road to socialism is not going to run through the state of Georgia.”

An even bigger stretch for Democrats is Texas, where Republican Sen. John Cornyn is seeking a fourth term. Former congressman Beto O’Rourke, who nearly knocked off GOP Sen. Ted Cruz last year, opted to seek


        }
#endif
      }
      return round_x_from_p(x, p, result, fudge_factor, base, lim, discrete_quantile_type());
   }
   else
   {
      unsigned x = lim;
      result = 0;
      T diff = hypergeometric_pdf<T>(x, r, n, N, pol);
      if (diff == 0)
      {
         // We want to skip through x values as fast as we can until we start getting non-zero values,
         // otherwise we're just making lots of expensive PDF calls:
         : hypergeometric_pdf<T>(x - 1, r, n, N, pol);
         --x;
#ifdef BOOST_MATH_INSTRUMENT
         if(diff != 0)
         {
            BOOST_MATH_INSTRUMENT_VARIABLE(x);
            BOOST_MATH_INSTRUMENT_VARIABLE(diff);
            BOOST_MATH_INSTRUMENT_VARIABLE(result);
         }
#endif
      }
      return round_x_from_q(x, q, result, fudge_factor, base, lim, discrete_quantile_type());
   }
#ifdef BOOST_MSVC
#  pragma warning(pop)
#endif
}

template <class T, class Policy>
inline unsigned hypergeometric_quantile(T p, T q, unsigned r,


for me.

The binding is almost done but still have a little bit to do on it.I love the look of these old reproduction fabrics.

These are reproduction Civil War fabrics, but the original fabrics which these are a copy of were possibly sewn on a machine like this. This is our 1879 Singer fiddlebasemodel 12 handcrank that sits in our foyer of our home. Singer started making the model 12 in 1865. The Civil War ended in 1865. I'm sure that some of the original Civil War fabrics were probably sewn on a the Singer model 12. Who knows maybe even this one.

My husband Pete fixed this sewing machine up and brought new life to once again and it still sews a very nice straight stitch. This old guy… because that’s just going to crack, so …

TOM: Yeah. No, not between the edge of the tile and the moulding.

LESLIE: (overlapping voices) And the wall.

STEVE: (overlapping voices) Exactly.

TOM: What you want to put there is a piece of – another piece of moulding called shoe moulding and that covers that gap, because you’re always going to have expansion and contraction between the baseboard and the tile.

LESLIE: It’s like a quarter round.

TOM: Yeah. It looks like quarter round.

STEVE: So some kind of caulk …

TOM: No, no.

STEVE: … would not do the trick?

TOM: Well, no. Not if – I mean …

LESLIE: (overlapping voices) Depends on how big the gap is.

TOM: Yeah.

LESLIE: I mean that’s something that I’ve done in a bathroom situation, where it’s tile to tile. I’ve used


the proper technique is, because maybe …

TOM: Yeah, but when it comes to manufactured homes, I think that those are just fine. I mean they, in some respects, are better built than stick homes.

LESLIE: Mm-hmm, and you’re not dealing with any weather conditions.

PAM: (overlapping voices) Yeah. We toured the factory. It was very impressive touring the factory; just to watch.

TOM: (overlapping voices) Yeah. They really are good homes.

PAM: Yeah. OK. I heard you talking about them a couple of weeks ago on the radio and …

TOM: Yep.

PAM: … the reason I was kind of curious about that. OK. So, I will do that; I will find out what kind of glue it is and maybe call the company.

TOM: Alright, Pam.

PAM: I’ll pursue it a little bit more. Thankson the pets. Not only do you have potentially dangerous things that they could get into around; it really does change the routine. I guess a lot of that applies to a disaster. When the surroundings are different, the pets can, I guess, get pretty confused.

MICHAEL: That’s right; they can. Pets are creatures of habit and they suffer more when you make poor decisions about what to do for and with them. You know, one of the things in the pet guide that we paid close attention to was providing information on helping you avoid poisoning.

Now, poisoning after a major weather event takes on an entirely new meaning because groundwater becomes contaminated; food supplies can become contaminated and animals are used to eating things without question, right?

LESLIE: Mm-hmm.

TOM:


the highest time that you’re going to get a high reading, because the house is more sealed up than it would be any other time of the year. So I think what you’ve identified here is a seasonal high for radon. You’ll find that it does go down across the space of the year if you were to do multiple tests. But because it’s over 4.0 picocuries per liter of air, you do need to put in a radon mitigation system.

The systems are reasonably expensive and probably (Leslie chuckles) in the $3,000 to $5,000 range.

STEVE: (overlapping voices) Ooh! OK.

LESLIE: But I mean, well worth it because there are health problems associated with radon.

TOM: Well, yeah and also a real estate problem if you want to sell this houseshelves but it doesn’t have to look very utilitarian. Leslie has got some great ideas to make sure your shelves look great, on today’s edition of Leslie’s Last Word.

LESLIE: Yeah, you know, shelves don’t have to be boring and you don’t have to head to the home center and get those simple, steel brackets that, you know, are completely invisible except for this ridiculous line on your wall with all these screws in it. If you take a little time and do your research – maybe head over to the craft store or even look at some architectural stores online – you can find beautiful, corbel-styled brackets. Use these instead of those simple, boring brackets and your shelf is going to stand out and really be a design


If the Democrats are serious about actual governing and fixing the many urgent problems that afflict our nation, they have to stop opposing any attempts to fix things like this. Charlie Pierce, who's now the political editor at Esquire.com, really lets loose his wrath on this latest example of sheer greed:

At a time when the president's getting some real traction with his new, not-quite-red meat rhetoric, and with an actual movement rising on the Left that, for all its diverse enthusiasms, is primarily about the opportunity buried in the visceral knowledge that we're all being swindled, and with the 2012 re-election utterly dependent on their doing something to turn the country's employment situation from surface-of-Mercury to merely bleak, the Democrats seem now ready to run the truck backand 42.
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23
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236
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71
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highest common divisor of 2888 and 139346.
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22
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92
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loads of trees in Scene mode, ( ie:build/add object - I used to do this once!).Just make your whole forest in Object mode, scale it how you want it, then, add the whole object created into the scene. Works well with anything static.

I like the idea of changing the measuring units, that would be very helpful... On another note, back to what Kreator mentioned, I have had a couple times where I wished I could export everything in a scene as a combined single object-just to play around with....

So apparently ruler isn't available in scene mode, or is there some other?.... What I'm trying to figure out is the "cad" measurements for the camera lens in scene mode..just as referenc.. In the picture below is a box thatthe projects.

“Send it back with constitutional relief,” Julian Falconer told the justices.

‘[excerpt] The Business Insider beamed that Harper showed Australia’s own anti-Putin conservative Prime Minister Tony Abbott “how to shirtfront the Russian president”–shirtfront being an Australian term similar to “smackdown.”’

Like many of the respected and informed commenters here…I am gone…
This site used have comments that were informative….
…now it is just a couple of people that copy and paste what I have already read…or…the commenter that always posts who is who ,without any correlation , substance or validity to the article…
Something went terribly wrong with this site…

HURON COUNTY — Sarah Mills hopes townships deciding whether or not to allow wind energy development can take the results of her study and understand the likely impacts.

Mills, a University of Michigan doctoral


This scheme produced a step-by-step method that was suitable for obtaining the set of parameters that describes the model. This method was evaluated under two scenarios: (a) using the data from a set of numerical simulations where the model was tested under the presence of artificial noises and (b) the information obtained from a set of experiments under different CNR. In both cases, a leave-one-experiment-out cross-validation study was considered to evaluate the model prediction capabilities. Feasibility of the parametric identification method was proven in both considered scenarios.performed using the SPSS software version 22.0 (SPSS Inc., Chicago, IL). The study was approved by the Institute Ethics Committee.

RESULTS
=======

During the 3-year study period, 160 children were diagnosed with scrub typhus. There was a clear seasonal trend with peaks during post-monsoon months---October (*n* = 48, 30%), September (*n* = 44, 28%), and August (*n* = 37, 23%). Mean (SD) age at presentation was 6.8 (3.2) years and about half (*n* = 87, 54%) were boys. Children presented from the adjoining districts of Haryana (*n* = 59, 37%), Punjab (*n* = 41, 26%), and Himachal Pradesh (*n* = 32, 20%) representing geographically both hilly Himalayan regions and sub-Himalayan plains. Fever was present in all with a median (IQR) duration of 9 (6, 11) days. Other prominent symptoms included respiratory


              87.7 (32.4, 145)
  Coagulopathy (INR \> 1.5) \[*n* (%)\]                    26 (20.8)
  Sodium mEq/L                                             133.5 ± 6.3
  Hyponatremia (\<135) \[*n* (%)\]                         99 (62)
  Glucosethe cooling system is increased and decreased in response to engine temperature and load. However, with this arrangement only the water level in the radiator is varied while the water jacket, formed in the cylinder block and cylinder head, remains full under the influence of a water circulation pump. Accordingly, this arrangement has suffered from the drawback that a power consuming water circulation pump is required, the temperature by which the temperature can be increased is limited by the fact that the water is prevented from boiling and in that the notable mass of water increases the weight and warm-up time of the engine.
Another arrangement of achieving the desired temperature control has included the use of a "dual" cooling system including two radiators which can be selectively used


Mets Have Lacked Since Reyes"

Even the most pessimistic Mets fan believes right now the 2015 team will be an improvement over the last five versions of the team. Given any kind of reasonable health one expects 82 wins at a minimum. The optimists foresee 89 or 90 wins and a wild card slot. If the Nats were to do […]

On this day in Mets’ history in 1975, the contract of outfielder and first baseman Dave Kingman was purchased from the San Francisco Giants. The 6-foot-6 Kingman, nicknamed Kong for his prodigious strength and power, was to give the Mets the fearsome home run hitter they had never had this early in their existence. “He was going […]     (e)      Eligible Legal Aid Organization. An “eligible legal aid organization” for the purposes of
this rule is a not-for-profit organization that provides legal services.
         (f)      Approval of Eligible Legal Aid Organization. Prior to the commencement of services
described in (d), the emeritus attorney shall submit an Eligible Legal Aid Organization Form to the
Secretary of the Board for approval. The emeritus attorney shall submit a separate form for each
eligible legal aid organization for which the attorney expects to perform pro bono services. The form
shall include the following:

              (1)      The name


and knowing who to trust is often tricky due to language barriers.

What about access to healthcare?

Similarly, linguistic barriers and not knowing where to get trustworthy information can also pose challenges in accessing healthcare for AAPIs. As a group overall, AAPIs are less likely to receive preventative care and cancer screenings. In this video Bernie discusses healthcare with AAPI community.

Stresses and challenges in life can affect mental health. However, AAPIs often face cultural stigma when considering mental health treatment despite the fact that many have faced extreme challenges like immigrating from war-torn countries:

As a largely immigrant and refugee population, Asian Americans face economic and language barriers that prevent them from accessing health care and make them more vulnerable to advanced depression and other mental health disorders. Stress related to|06.16.14|Waith Words for the Day

If you become attuned to your Soul’s purpose, you will see everything is presented to you for a reason. And, you can view even what appears to be adversity as something positive, because it is a growth opportunity for you.
Source: Unpublished Waith Transcript, August 27, 1987


Trance (2013) Directed by Danny Boyle. Starring: James McAvoy, Vincent Cassel, Rosario Dawson. IMDB says: “An art auctioneer who has become mixed up with a group of criminals partners with a hypnotherapist in order to recover a lost painting.”

Even though Trance isn’t as initially powerful as some of Danny Boyle’s other masterful films, it’s still a lot of fun and an engaging crime story that aims higher than most. Comparing the film to Danny Boyle’s other work is inevitable but if given the chance, Trance will hold you in its grasp until the final frame.

The events of the story are initiated by Simon (James McAvoy,) who narrates the details of his job at a high priced art auction. He explains the simple procedures the auction has in placecircumferential systolic strain of the different layers, peak systolic radial strain and rotation degrees of the different short-axis levels detected by 2D--STI are very sensitive for assessing the systolic function in HCM patients. In the clinical implication, the study can help us to know the early cardiac dysfunction of HCM patients, then to give them early treatment and assess the effect after the treatment.

Limitations {#Sec16}
-----------

The greatest limitation of this study is that the relationship of decreasing short axis functions to a clinical outcome or event is not investigated. Another important limitation is the small number of patients. The third limitation is that we don't evaluate the relationship with other image techniques, such as cardiac MR, SPECT.

2D--STI

:   2-dimensional speckle tracking imaging

HCM

:   Hypertrophic cardiomyopathy

IVSD

:


Alternatives to the Death Penalty, who has been campaigning against the execution, also welcomed Greitens' decision.

"We have much to celebrate right now but also much to acknowledge how we got to this day that we need to hold these rallies. Our capital punishment is broken, and our judicial system still has major flaws," Pratt told Al Jazeera.

"This is a wakeup call and a siren, this is about more than just Marcellus' case. Naturally, we are happy with today's result, but we must make sure that cases like Marcellus' don't arise again."

Before Greitens' statement, more than 200,000 people had signed a petition asking for the governor's intervention.

"The voices of the people definitely mattered," Pratt said. "Naturally, we're still vigilant, we're still here to see this process and that heseeks to quell an imminent uprising in Jerusalem before the Emperor arrives. Failing to secure Yeshua's body, Clavius, with the support of his loyal aide Lucius, attempts to locate and question the disciples of Yeshua and those involved in his crucifixion and burial for clues to his disappearance.

Numerous leads are dug up, and their accounts soon become increasingly miraculous and difficult to believe. Some of the followers, like a prostitute named Mary Magdalene and a man named Bartholomew, seemingly speak only in riddles and refuse to betray any others. Clavius' intense investigation begins to disturb both Romans and Hebrews alike, and Pilate, under pressure from many sides and fearful of Caesar's wrath, becomes increasingly distant and unsupportive. Running out of new leads, Clavius revisits a disgraced Roman soldier,


the owner of the business Would not recommend”

“I was so freaked out with planning my wedding and started really dreading the day fearing everything would go wrong, and Anvara really calmed me down and refocused me on enjoying the period leading up to the big day and especially on the day of our wedding providing wonderful flowers that were so beautiful. ”

“We loved their work and our guests commented on how great our flowers were, and our experience with Anvara, really made us feel at ease. At first we were hesitant given the prices and that they operate from home, but my husband suggested we meet with them as they seem to operate on a similar concept as online retail, and were so pleased that we did.”

“I wouldQ:

How to get Node Url in RSS view?

We are using the default RSS feed view found at /admin/structure/views/view/frontpage. We want to change the Show to be Fields so we can setup up which field should be used for the title, link, description, creator, and publication date.
When we attempt to add the node url field we cannot find it. How to add the absolute URL of the node?
We have tried searching for, but cannot find it:

Content: Path
Node URL

A:

It's called Link to Content.
Path field could also be used in older 8 versions (you could construct the full URL with replacement patterns while overwriting the field output).
But the Path field is deprecated in 8.5 and you can use Link to Content instead, with Output the URL as text


1. Field of the Invention
The invention relates to a method of adapting the engine to the octane number of the fuel. This invention notably relates to controlled-ignition engines the ignition advance of which can be controlled electronically. More particularly, the invention relates to a method of adaptation by incrementing the learned octane number of the fuel.
2. Description of Related Art
At the present time there are various types of fuel that have different characteristics. These characteristics include the octane number. Among the various fuels, the octane number may commonly adopt the approximate values of 98, 95, 91 and 87. Fuels with octane numbers of 98 and 95 are often used in Western Europe, those with an octane number of 91 may be encountered in the United States and thoseunderstanding of direct human-environment living balance. The successful bi-directional interdependence between human-beings and the natural environment varies in form and practice among indigenous nations around the world. The differences between nations constitutes the variety of human/environment adaptions to micro-climates and environments. This organically evolved approach to diverse adaptions can be clearly recognized as the main success for all of human survival.

Despite the considerable benefit to human survival achieved through a balance between human want and nature's capacity to reproduce more direct efforts to control nature (such as row cropping, pesticides, irrigation, transplantation and since the 1990s the use of genetic modification) methods for expanding the production of food for biological and commercial benefit introduced a radical alteration and basic reductions in the quality of food and nutrition.

Chronic disease


must know that their age-old systems of food production and the evolved adaptation of these systems to respond to climate and environmental changes are the systems on which all of humanity will have to turn if the current "new" systems fail. There is no doubt that these new systems will fail. When compared with the thousands of years humans have successfully engaged in "earth gardening" the current food production systems pail. Quantity for quality has been the exchange since the advent of industrial and GMO for production. Much more food with less or little nutritional value, but substantially more harmful content to the human body may be a commercial success, but it is a failure for human health and human survival.The Republican tax bill allows them to close factories and ship jobs out of Wisconsin while making their rich shareholders even richer.

“Wisconsin deserves a governor who stands up for workers and fights to keep jobs,” said Democratic Party Chair Martha Laning. “Walker has shown that he’s not interested in making efforts to stop Wisconsin plant closings like Oscar Mayer and Appleton Coated. Republican tax and economic policy focuses only on those in the boardroom, not the workers in the lunchroom.”

Wisconsin deserves to know: Did Walker do anything to keep these good jobs and factories in Wisconsin? Did he meet with Kimberly Clark or make any attempt to stop the job cuts caused by Republican tax plans?

During his 25 years in public office, Walker has pushed tax policy that


Today, it is a frigid desert world with a carbon dioxide atmosphere 100 times thinner than Earth's. But evidence suggests that in the early history of our solar ...

An international team of astronomers, including Professor Bob Nichol from the University of Portsmouth, has confirmed the discovery of the most distant supernova ever detected – a huge cosmic explosion that took place 10.5 ...

139 comments

Earth's broadcast signals have reached every star within about 80 light years from the sun – about 8,531 stars and 3,555 Earthlike planets

Even for the closest solar systems (4ly away) our signals are so weak that not even theoretically optimal amplifiers would pick them up.

The Fermi paradox says billions of Earthlike planets exist in our galaxy, yet no aliens have contacted or visited us.

I can'treally like, we all felt that talking about it extensively to the media and other strangers would open us to ridicule, as had happened to so many who revealed their own experience with E.T.So, we all determined that it would be best to stay up on the subject and find out what others have said and done, but not to open ourselves to scrutiny, particularly by government agencies.There is no way that governments are unaware of the E.T. presence on and above Earth, even though they disavow any knowledge.

Even if they picked up our signal their reply would not be present for roughly 150 000 years. The probability of of surviving as a species for the next 150k years is extremely slim so yeah, we probably will never


have a first-hand encounter themselves, otherwise it will be considered to be hearsay

@Telekinaticactually it will always be considered hearsay unless you can provide empirical evidence. see at least the first 4 minutes:https://youtu.be/m5WK_7GQ9GQ

I think CFD has it spot on except it's a kind of census. "Just how many total nutjobs are we relying on to make our quota of hits on a given story?"

you might have something there:it does appear to feed the system where the number of replies on a given thread show "popularity" allowing PO to advocate for greater financial compensation from adverts displayed on their site

Human-level intelligence is a blip on the cosmic scale. It signifies an almost instantaneous transition from the biological to the machine.

Once biologicals become smart enough to build machines, they quickly designTHE HUMAN MIND, a blanket statement that involves ALL human minds, no exceptions.You may backpedal in behalf of Frumpy, but her statement remains.Innumeracy is only YOUR opinion, in tandem with YOUR Confirmation Bias

In fact, your use of this in a logically fallacious manner confirms your own confirmation bias; you ignore consensus reality by claiming that consensus reality is confirmation bias. This is, as @BiteMe says, true confirmation bias: rejecting consensus reality by claiming it's somehow not real. It's also proof of schizoid ideation, again as @BiteMe claims. Thanks for demonstrating this so succinctly.

Actually this is incorrect. It's possible to account for this particular type of "insanity." The method is called "The Scientific Method."

You appear to be unfamiliar with it, in addition to your innumeracy. Noted that you are


and science is experiment, and like most deniers you discount experiment because you are innumerate.

- da schmo

I wasn't attempting to "demonstrate" pro or con. Sokal isn't worth my time. Read my previous posts. I already had said that Philosophy is a PRECONDITION of the sciences, and with science comes experimentation. So?

I had revealed to one and all that I am on a "Learning Curve" wrt the Standard Model and Electric Universe Theory. Therefore, for you (or anyone) to say that I am holding a Confirmation Bias wrt either of these two THEORIES

EU is not a theory, nor is it even a hypothesis. It is a disproven conjecture and blahhh

In short, you are innumerate, mesmerized by navel-gazing solipsistic rhetorical philosophy, and incapable of understanding why you are wrong: anthat I dismiss anything said and done by competent physicists? IF they are truly competent, they will continue to seek and find the TRUTH. I don't think that they give a flying fck about YOUR Confirmation Bias, although I'm sure they appreciate your anonymous support for their work. That also goes for EU physicists, and I respect THEIR work also.

As far as AGW goes, it's SUMMERTIME...and the living is easy. IF the glaciers are still melting in December. that is when i will become suspicious...although it could also mean that the Earth is entering a warming cycle all on her own. Can you adapt? I can.

LOL You express your ideology very well.Um...your OWN vadge? You sure about that?Nah, not THAT Fish. GhostofOtto'sAss is the one who proclamed that


by quoting ...

Condoms are a nuisance, but necessary. I can only use king-sized...LOL

Maybe your imagination needs a condom... THAT might be king-sized...

- WhydG

Oh yeah...I see that your comment was removed. You mentioned tuna fish and Miracle Whip. Then you mentioned "unless there's a yeast infection involved". Hmmm someone must've read something into that.Imagination? Not at all. I'm a big guy...6 feet 6 1/2 inches tall. Sorry to dash your hopes, Why'd.Like I said - king sized. Being tall AND handsome does have its advantages that most other men don't have.

Imagination? Not at all. I'm a big guy...6 feet 6 1/2 inches tall. Sorry to dash your hopes, Why'd.Like I said - king sized. Being tall AND handsome does have its advantages that most other men don't have.

And yetis presented when you have made your last post. The claim is not baseless. We'll do it your way.

A claim is not baseless unless the evidence indicates it as such once the COMPLETE evidence is presented

OK. You're a worthless piece of dog shite. Now, we will consider that to be correct until the COMPLETE evidence is presented when you have made your last post. The claim is not baseless. We'll do it your way.

Piece of shite.

Okay Jim, Everyone knows that all Englishmen are cross-dressers, and love to be whipped with leather riding crops. That would describe you to a "T". Let's see you prove otherwise. Nancy boy.

tell you what, feel free to put your money where your mouth is:write it all up and submit it to a peer


as well...I've posted about this incident before on this forum and was surprised and appalled that not one person asked about details, which, as an ardent fan of science, would be the first thing I would do. By questioning me with the intent to trip me up would also have been fine. Alrighty. then. Let's start with;1. Altitude? 2. Distance? 3. Shape? 4. Coloring? 5. Moving/hovering? 6. Windows? 7. What did binoculars aid you in seeing?Answer those and I will then have further questions.Oh... Scientific method also infers documentation. Lots and lot's of it....

Telekinetic Sep 02, 2011 Rank: 1.9 / 5 (9):About 5 years ago, I witnessed a UFO of the silver cigar tube type at approximately 500 feet in the air. It was dusk but there washospitable enough to have had many extraterrestrial civilizations for over millions of years.

... UFO of the silver cigar tube type at approximately 500 feet in the air. It was dusk but there was still plenty of light to see it clearly. It was making a slow trajectory above a very heavily wooded area and with binoculars, I could see that there were no wings, tail assembly, ailerons, markings, or sound. There was a narrow slit in the front that I assume was for visibility. Its movement was completely straight and was definitely not a gas filled blimp.

Approx. size?Distance from you?Why would you say not a blimp? Was it windy?I know you will rail at this, but it's important info. Were there any alcoholic beverages ingested? Or prescription drugs?


Cannabis? Even - cigarets...?

The overall length was about 35 ft. and approximately 8 ft in diameter with both ends rounded. Its distance from where I stood was 40 ft and about 500 ft. high. The flight instructor was my flight instructor at the time. I neither imbibed alcohol or ingested anything mind-altering- i was sober as a judge at the time. Now, a good detective determining the veracity of a story doesn't need anymore details other than comparing the story told nearly 5 years ago to the story told recently. And as an illustration of how idiotic my detractors are, they all voted unanimously in favor of Dark_Solar'spost where he states clearly and unequivocally that other intelligent civilizations likely exist, which is corroborative of my statements. You patheticft and about 500 ft. high. The flight instructor was my flight instructor at the time. I neither imbibed alcohol or ingested anything mind-altering- i was sober. Now, a good detective determining the veracity of a story doesn't need anymore details other than comparing the story told nearly 5 years ago to the story told recently.

- Telekinetic

You have described a cylindrical-shaped ET spacecraft. The race of E.T.s use several models of spacecraft in the skies above us. Some are triangular or cylindrical, but most are disk-like, smooth and windowless. They emit a plasma-like aura that pulses, surrounding the spacecraft, which led us all to believe that the plasma is emitted by their propulsion system.The E.T.s recharge their propulsion systems with antimatter generated in lightning storms and go invisible


during that time

And as an illustration of how idiotic my detractors are, they all voted unanimously in favor of Dark_Solar's post where he states clearly and unequivocally that other intelligent civilizations likely exist, which is corroborative of my statements. You pathetic knuckleheads can't comprehend what's written(..)

- Telekinetic

Yes, I noticed that also. The 5 trolls rated him all FIVES without comprehending the reality of what was posted. LMAOMost humans don't, or rarely look up at the sky while walking, and even sitting, unless birdshit happens to land on their head. It's just not the human thing to do. to watch the skies. The action is all happening in front of, or around them. They are just so disinterested, judging by the comments I read in this thread, plus writtenand oral mindsets of those I have spoken to offline. That means that "the man in the street" or those in Physorg threads are uninterested in the interactions between man and ET.

(cont'd)@TelekineticIt is a normal practice for humans to declare ANY kind of personal experience that involves an extraterrestrial presence to be a mental disorder of some type; not merely due to their not having had the same kind of experience with the ET phenomena, but due mostly to the Fright Factor which is illustrative of the Fight or Flight syndrome which humans have built-in to their primitive psyche.E.T.s are aware that the vast majority of humans are chickenshits who would prefer to believe that they reign supreme universally, but who concede socially that there IS a SLIGHT


superoxide dismutase reversed the killing of avirulent M. avium by untreated or TNF-treated macrophages. This abrogation was also apparent in chronic granulomatous disease (CGD) macrophages, which were inefficient at generating reactive oxygen intermediates. Moreover, macrophages from CGD patients killed avirulent M. avium as efficiently as cells from normal individuals. We conclude from these results that 1) GM-CSF and TNF-alpha, alone or in combination, increase effector functions of macrophages against virulent and avirulent strains of M. avium; 2) reactive nitrogen intermediates seem to be involved in this effector mechanism; and 3) superoxide dismutase protected M. avium against macrophage effector function, seemingly by protecting the bacteria against endogenous superoxide anion. The implications of these findings for host resistance to atypical mycobacteria are discussed.Actions

Fred Guttenberg, the father of a slain Parkland student, said on Twitter that he tried to approach Supreme Court nominee Brett Kavanaugh only for the judge to ignore him.

The incident occurred as the Senate Judiciary Committee took a recess shortly after noon Tuesday.

"Just walked up to Judge Kavanaugh as morning session ended. Put out my hand to introduce myself as Jaime Guttenberg's dad. He pulled his hand back, turned his back to me and walked away. I guess he did not want to deal with the reality of gun violence," Guttenberg tweeted.

White House deputy press secretary Raj Shah addressed the moment on Twitter, saying, "As Judge Kavanaugh left for his lunch break, an unidentified individual approached him. Before the Judge was able to shake his hand, security had


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        };

        AnimGraphObjectData(AnimGraphObject* object, AnimGraphInstance* animGraphInstance);
        virtual ~AnimGraphObjectData();

        MCORE_INLINE AnimGraphObject* GetObject() const                { return mObject; }
        void SetObject(AnimGraphObject* object)                        { mObject = object; }

        // save and return number of bytes written, when outputBufferhasError)                    { SetObjectFlags(FLAGS_HAS_ERROR, hasError); }

        AnimGraphInstance* GetAnimGraphInstance() { return mAnimGraphInstance; }
        const AnimGraphInstance* GetAnimGraphInstance() const { return mAnimGraphInstance; }

    protected:
        AnimGraphObject*    mObject;               /**< Pointer to the object where this data belongs to. */
        AnimGraphInstance*  mAnimGraphInstance;    /**< The animgraph instance where this unique data belongs to. */
        uint8


   }
    }

    template <class T>
    void AnimGraphObjectData::LoadVectorOfObjects(AZStd::vector<T>& inOutObjects, uint8** inOutBuffer, uint32& inOutSize)
    {
        size_t numObjects;
        LoadChunk((uint8*)&numObjects, sizeof(size_t), inOutBuffer, inOutSize);

        if (*inOutBuffer && numObjects > 0)
        {
            inOutObjects.resize(numObjects);
            const uint32 sizeInBytes = static_cast<uint32>(numObjects * sizeof(T));
            LoadChunk((uint8*)&inOutObjects[0], sizeInBytes, inOutBuffer, inOutSize);
        }
    }
} // namespaceprocesses, and cognitive decline.[10](#fsb220084-bib-0010){ref-type="ref"} Indeed, a DHA deficient diet is involved in the pathophysiology of memory impairment and several mood disorders such as anxiety and depressive‐like behaviors.[11](#fsb220084-bib-0011){ref-type="ref"}, [12](#fsb220084-bib-0012){ref-type="ref"}, [13](#fsb220084-bib-0013){ref-type="ref"}, [14](#fsb220084-bib-0014){ref-type="ref"}, [15](#fsb220084-bib-0015){ref-type="ref"} DHA deficiency in the CNS is also paralleled by an increased expression of pro‐inflammatory cytokines and a modification of neuronal plasticity‐related gene expression, including the early growth response protein 1 (Egr‐1) and the activity‐regulated cytoskeleton‐associated protein (Arc‐1),[16](#fsb220084-bib-0016){ref-type="ref"} ultimately associated with learning and memory formation.[17](#fsb220084-bib-0017){ref-type="ref"}, [18](#fsb220084-bib-0018){ref-type="ref"} Such evidence prompted the investigation of several clinical trials with DHA on neurodevelopmental disorders, including autism and attention‐deficit/hyperactivity disorder.[19](#fsb220084-bib-0019){ref-type="ref"} Despite the fact that there is a growing number of trials testing the efficacy of n‐3 PUFAs in the treatment of different psychiatric disorders, only a few studies investigated the efficacy of DHA


were diluted 1:10 and aliquots of 2 μl per reaction were run in duplicate. Thermal cycling conditions were 2 minutes at 50°C, 10 minutes at 95°C, and 40 cycles of 15 s at 95°C and 1 minutes at 60°C, followed by the melting curve analysis on a Bio‐Rad CFX Connect Real‐Time system. Primers used for qRT‐PCR were caspase‐1, inducible nitric oxide synthase (iNOS), interleukin 1β (IL‐1β), tumor necrosis factor (TNF), activity‐regulated cytoskeleton‐associated protein 1 (Arc‐1), early growth response protein 1 (Egr‐1), brain‐derived neurotrophic factor (BDNF), and glial fibrillary acidic protein (GFAP). Actin and transcription factor IIB (TFIIB) were used as housekeeping genes for quantity normalization. For primers' sequences see Table [3](#fsb220084-tbl-0003){ref-type="table"}.

######

Murine primers used for the quantitative RT‐PCR

  *Primers*   Forward          also counterstained with Neuro‐Trace 640⁄660 deep‐red Fluorescent Nissl Stain (1:200; Thermo Fisher Scientific). After further washes in PBS, the sections were mounted using an anti‐fade medium (Fluoromount; Sigma, Milan, Italy) and examined under a confocal laser‐scanning microscope (Zeiss CLSM700, Oberkochen Germany). The specificity of immunohistochemical labeling was confirmed by the omission of primary antibodies and the use of normal serum instead (negative controls). Confocal acquisition of the brain area of interest (motor cortex and somatosensory cortex) was identified by a 10 × objective (Plan‐Apochromat, Zeiss; NA = 0.30; zoom factor 0.5) and captured through a confocal laser‐scanning microscope (CLSM700; Zeiss, Oberkochen, Germany). The following acquisition settings were used: image format 1024 × 1024; image size 1279.1 × 1279.1 μm; Airy Units 1.0 producing an optical section thickness of 5.2 μm; pixel dwell time 12.61 μs. The confocal image acquisitions


KO mice might have a physiological impact in this mouse model deficient for DHA synthesis, we also performed some behavioral analyses. Thus, to examine responses to an unfamiliar environment, Elovl2 WT and KO mice were evaluated in the open field test. Our results show that even if no statistical difference was present in the number of visits to the center zone, the percentage of time spent and the distance covered in the center zone were statistically significant between the two groups of animals (Figure [5](#fsb220084-fig-0005){ref-type="fig"}A). The same set of animals was also subjected to the NOR test, in which KO animals show a tendency to spend less time, although not significant, at the novel object compared to WT (Figure [5](#fsb220084-fig-0005){ref-type="fig"}B), suggesting no deficit in object memory. Next, weas well as in the pathogenesis of several cognitive disorders.[56](#fsb220084-bib-0056){ref-type="ref"}, [57](#fsb220084-bib-0057){ref-type="ref"}, [58](#fsb220084-bib-0058){ref-type="ref"} Of note, several cytokines have been reported to suppress synaptic plasticity by suppressing Arc expression in a BDNF‐dependent manner and the latter, together with Egr‐1, is a transcriptional regulator of Arc, thus accounting for our marked changes in Arc‐1 at both mRNA and protein level, while Erg‐1 and BDNF only show changes in their mRNA but not protein. However, the notion that pro‐inflammatory cytokines are only expressed in the brain in response to pathological stimuli has been challenged by emerging data, indicating that certain cytokines can also play an active role in synaptic plasticity in physiological condition.[59](#fsb220084-bib-0059){ref-type="ref"}

Yet, the ability of fatty acids to modulate both inflammation and synaptic functions is coming to the foreground and alterations


of their availability, either due to insufficient dietary consumption or impaired metabolism, might play a role in the pathogenesis of several cognitive disorders.[38](#fsb220084-bib-0038){ref-type="ref"} In this regard, significant differences in the synaptic proteome of DHA‐adequate and DHA‐deficient mouse brains have been reported[60](#fsb220084-bib-0060){ref-type="ref"} providing a molecular basis for the significant impact of nutritional DHA on some brain functions such as learning and memory. The evidence that free DHA can enter the brain through the mfsd2a and that this transporter is regulated both in Elovl2 mice and upon DHA supplementation suggests not only that Major Facilitator Superfamily Domain containing 2a (Mfsd2a) plays a compensatory role to balance the DHA levels in the brain of Elovl2 mice but also that exists a dynamic interplay between DHA synthesis and DHA uptake in theiNOS, IL‐1β, and TNF observed in Elovl2^−/−^ mice. Although our findings do not clarify the precise cellular source of cytokines, however, our results suggest a temporal correlation between the microglia morphological changes and cytokines production. More studies are required to establish the cellular source of cytokines and, in particular, to demonstrate that their production can be attributed to microglia.

Furthermore, since microglia also play a role in synaptic remodeling and neuronal plasticity,[61](#fsb220084-bib-0061){ref-type="ref"} it is also possible that such activated inflammatory status is somehow associated with the downregulation of markers of synaptic plasticity in Elovl2^−/−^ mice. This is particularly important since the brain and the immune systems are engaged in a bidirectional crosstalk and our data suggest that microglia might engage in mediating such a complex interaction. Furthermore, the fact


area (*n* = 3/4). (**c--h**) Immunostaining of pSMAD1/5/9: signal increases in the distal part of chick wing buds over time (**c--e**) and is enhanced in HH24g mesenchyme (**f**) compared to contralateral HH24 buds (*n* = 3/3 c) but not in HH20-HH20 grafts (*n* = 2/2 g); signal is enhanced in apical ectodermal ridge above grafts in HH24g mesenchyme (asterisk-**h**) but not adjacent regions of ridge (*n* = 2/2 - arrow-**h**). (**i--j**) Lysotracker staining of apoptotic cells reveals no difference in HH24 (**i**) and HH24g (**j**) mesenchyme (*n* = 5/5) -- asterisks indicate anterior necrotic zone. (**k**) Flow cytometry of wing bud distal mesenchyme: PBS- and Noggin-soaked beads do not significantly affect proportion of cells in G1-phase after 8 hr compared to left wing controls (Pearson's χ^2^ test -- p=0.1 and p=0.4, respectively); Noggin-soaked beads implanted at HH20 (+Nog) producenot inhibit proliferation by compromising cell survival. Taken together, these results suggest that BMP signalling in HH24g mesenchyme maintains an intrinsic cell cycle programme.

FGF response is reset in HH24g mesenchyme {#s2-4}
-----------------------------------------

The maintenance of BMP signalling in HH24g mesenchyme could also reduce proliferation via inhibition of FGFs produced by the apical ectodermal ridge. However, consistent with the observation that *Grem1* expression is maintained in HH24g mesenchyme ([Figure 2g,h](#fig2){ref-type="fig"}), we have previously shown that *Fgf8* expression is maintained in the apical ectodermal ridge above grafts of distal mesenchyme from much older wing buds - including in tissue that would have developed to stage HH36 if left in situ (or day 10 of incubation -- the ridge normally regresses at HH29/30 in the chick wing at day 6--6.5 of incubation -


development that we describe here provides a mechanism by which cells can be instructed by autocrine BMP signalling in the absence of spatial gradients. It will be important to identify if this mechanism operates in other patterning systems.

Materials and methods {#s4}
=====================

Chick husbandry and tissue grafting {#s4-1}
-----------------------------------

Wild-type and GFP-expressing Bovans Brown chicken eggs were incubated and staged according to Hamburger Hamilton ([@bib10]) HH19 is embryonic day 3, HH24 - day 4, HH27 - day 5, HH29 -- day 6 and HH30, day 7. For tissue grafting, the polarizing region was discarded and a stripe of 150 µm of distal sub-AER mesenchyme about 500 µm long was dissected from HH27 wing buds. The ectoderm was removed after incubation in 0.25% trypsin at room temperature for 2 min and the mesenchymeanti-digoxigenin antibody (1:2000) at 4°C overnight, then washed in MAB buffer overnight before being transferred to NTM buffer containing NBT/BCIP and mRNA distribution visualised using a LeicaMZ16F microscope.

Immunohistochemistry {#s4-5}
--------------------

Embryos were fixed in 4% PFA for 2 hr on ice, washed in PBS and transferred to 30% sucrose overnight at 4°C. Embryos were frozen in OCT mounting medium, fixed to a chuck and cryosectioned immediately. Sections were dried for 2 hr and washed in PBS containing 0.1% triton for 10 min at room temperature. Sections were blocked in 0.1% Triton, 1 -- 2% hings/serum for 1 -- 1.5 hr at room temperature. Primary antibody solution was added (1:500 rabbit anti-PSMAD1/5/9 Cell Signalling Technology -- D5B10) in PBS/0.1% triton/1 -- 2% hings, before coverslips were added and slides placed in a humidified chamber at 4°C for


and right wing buds embryos showed that differences are less than 1%).

Bead implantation {#s4-7}
-----------------

Control affigel blue beads (Biorad) were soaked in PBS/4 mM HCl. Affigel beads were soaked in Human Noggin (0.025 μg μl^−1^ - R and D) or human BMP2 protein (0.025 μg μl^−1^ and 0.05 μg μl^−1^ - R and D) dissolved in PBS/4 mM HCl. Control heparin beads (Biorad) were soaked in PBS. Heparin beads were soaked in human FGF8 (0.5 μg μl^−1^ - R and D dissolved in PBS. Beads were soaked for 2 hr and implanted into the distal mesenchyme using a sharp needle.

Funding Information
===================

This paper was supported by the following grants:

-   http://dx.doi.org/10.13039/100004440Wellcome Trust 202756/Z/16/Z to Joseph Pickering, Constance A Rich, Holly Stainton, Kavitha Chinnaiya, Matthew Towers.

-   Spanish Ministerio de Economia BFU2017-88265- Puntil HH24). RNA-seq analyses revealed that, in HH24g, Bmp2/4/7 expression is maintained, whereas FGF and Grem1 expression is reset. Based on these results, authors draw conclusions that the mesenchyme cells terminate growth by an intrinsic cell cycle timer in the presence of e-m signalling. While the results are interesting, many changes are required to bring the manuscript to publishable form. Most critical is to perform further functional experiments to test the role of genes identified by RNA-seq to validate the model. It would also be critical to provide evidence that the permissive signals from the AER is required for the duration of mesenchyme cell proliferation. The major issues raised by the reviewers are listed below. If you think you can make these changes in 2-3 months, we would


now and we feel that experiment 1 provides strong evidence for the endogenous role of BMP signalling in the limb.

> 8\) The term \"intrinsic cell cycle timer\" needs more explanation. Did authors mean that cells memorize the positional information as an epigenetic memory, gene expression, protein accumulation, or cell adhesion? If they consider all these possibilities, other conclusions should also be considered.

We use the term "intrinsic timer" to explain that cell cycle parameters are controlled intrinsically in the mesenchyme, but still require permissive signals from the apical ridge. This was a major part of our 2015 paper and we will explain this better in our revision. We do not yet know what the nature of the clock is.

Revision: At this stage we do not feel we have enoughdidn’t have long to be surprised—mere hours after arriving at work, he was standing in L.A.’s Laurel Canyon neighborhood, his sack full of mail for Benicio Del Toro and the other residents of Del Toro’s neighborhood.

Morris delivered nine envelopes and one large, heavy box to the Del Toro household. The Traffic star was reportedly not home, but that was fine by Morris.

Just 90 minutes after landing at LAX, Morris was on a plane again back to Illinois to complete his normal route and clock out one last time.

What’s next for Morris? Spending more time with his grandkids and dusting off his tennis racket, according to the longtime public servant. One thing is for sure, though: He won’t forget his day delivering Benicio Del Toro’s mail for a long,


idea to minimise mouse usage.
By simply pressing two keys access the Easy History Extension(Default keys: Ctrl+Space).
With the help of Easy History you can also easily navigate though your Browser history with a very clean interface.
You can also choose whether you want the history to be sorted according to the time or your visits to the link.
Time: History will be arranged in a manner such that the last visited link will be on the top.
Visits: History will be arranged in a manner such that the most visited link will be on the top

be inferred from the splitting of the GDR peak. At finite temperature the nuclear shape fluctuates, and the relationship between the shape and the observed resonance properties is more complex. In the adiabatic limit the observed GDR strength function is calculated through an average over a thermal ensemble of shapes corresponding to all quadrupole degrees of freedom [@A92]. These include both the intrinsic shape and the nuclear orientation with respect to its rotation axis. The fluctuation theory explains successfully both the observed cross-section and angular anisotropy of the GDR radiation [@AB90; @eric; @gund].

In recent years, a wealth of experimental results for the GDR has become available in wider regions of temperature and spin [@gund; @exp; @exp1; @R96]. In the fusion experiments, higher excitation energies are usually accompanied by


Primary hepatic malignancy: surgical management and determinants of survival.
To further define the clinicopathologic features and determinants of survival, we reviewed the cases of 110 patients with primary hepatic malignancy managed surgically between 1975 and 1986. Presenting signs of symptoms were pain (57%), fatigue (48%), abdominal mass (40%), and weight loss (33%). Twenty-six percent of patients had a history of hepatitis or cirrhosis. Histopathologically, tumors were hepatocarcinoma (72%), fibrolamellar variant (7%), cholangiocarcinoma (9%), mixed (7%), and other (5%). Resectability rate with curative intention was 67%. Exploration and biopsy alone was performed in 27% and palliative resection in 6%. Hospital mortality was 9%, and serious morbidity was 22%. Perioperative morbidity and mortality were significantly associated with operative blood loss. Median survival was 12.6 months, with a 5-year survival of 18%.the laser head 1. However, as shown in FIG. 1B, if the workpiece 6 is sufficiently thin to allow proper heating of the worksite 5 the arc welding torch 7 may be provided on the opposite side of the workpiece 6 from the laser head 1 so as to make the system more flexible. Further, in these conventional devices some type of electro-mechanical control (not shown) is provided in order to move the workpiece 6 with respect to the stationary laser head 1 and arc welding torch 7 or to move the laser head 1 and arc welding torch 7 with respect to the stationary workpiece 6.
In operation, the incident laser beam 4 of a conventional laser-arc welding device causes the worksite 5 to melt and vaporize which


Dpto. Astrofísica, E-38206 La Laguna, Tenerife, Spain\
bibliography:
- 'reference.bib'
title: Constraining the inner density slope of massive galaxy clusters
---

cluster; lensing; stellar dynamics; dark matter halo;

Introduction
============

In the $\Lambda$CDM cosmological model cold dark matter dominates the matter budget of the Universe, and much of it clusters into dark matter halos. Gas condenses at the centres of these haloes, forming stars and giving birth to galaxies [@White_Rees1978; @White_Frenk1991]. Measuring the distributions of dark and baryonic matter at the centres of haloes provides a key test of $\Lambda$CDM and theories of galaxy formation.

Over the past three decades, the evolution of pure cold dark matter has been calculated with great precision by means of N-body simulations [@DEFW; @NFW96; @NFW97; @Jenkins2001; @Diemand2007; @Springel2008; @Gao2011] [for a review see @Frenk_White_2012]. In particular, @NFW96 [@NFW97 hereafter NFW] havethe distribution function of the stars, $\Phi_{\rm tot}$ the gravitational potential, and $n$ is the luminosity density.

In this work, we adopt the numerical Jeans-Anisotropic-Modeling routine of [@Cappellari2008] with the multi-Gaussian Expansion (MGE) technique [@Emsellem1994; @Cappellari2002], which is widely used in galactic dynamical modeling [e.g. @Cappellari2008; @Cappellari2011; @Newman2015; @Hongyu2016; @Hongyu2017]

To determine a unique solution, the JAM routines make two assumptions [@Cappellari2008]:

1.  the velocity dispersion ellipsoid is aligned with the cylindrical coordinate system ($\overline{v_R v_z}=0$),

2.  the anisotropy in the meridional plane is constant, i.e. $\overline{v_R^2} = b\overline{v_z^2}$, where $b$ is related to $\beta_{z}$, the anisotropy parameter in the $z$ direction, defined as

    $$\label{eq:beta}
      \beta_{z} \equiv 1 - \frac{\overline{v_z^2}}{\overline{v_R^2}} \equiv 1 - \frac{1}{b} \, .$$

If we set the boundary condition, $n\overline{v_z^2}=0$


a much better fit than dPIE because it has more free parameters. MGE fits most clusters within an error of 10%, while dPIE fits most cluters within an error of 40%, which is higher than the errors estimated by @Newman2013a ($\sim$ 5%) from fitting the surface brightness profiles of their clusters. This discrepancy could be due, in part, to differences in the properties of the real and simulated galaxies but, as we will show later, it has no affect on the inference of the parameters of interest here. Both MGE and dPIE give a bad fit to CE-19 due to contamination from two line-of-sight satellites that are very close to the BCG (within 15 kpc).

![Difference between recovered and true surface luminosity profiles for CE-13 and CE-19. Blue linesthat these distributions are the same for all clusters; this is not necessarily the case and the product can be strongly affected by inclusion of one or two clusters with a very different $\gamma_{\rm gNFW}$ distribution. In fact, @Newman2013b point out that excluding the cluster with the lowest $\gamma_{\rm gNFW}$ (A2537), the mean $\gamma_{\rm gNFW}$ would change by $\sim$ 40% from 0.50 to 0.69. Using the bootstrap method, we find probabilities of 3.5%, 17.1% and 49.1% for the mean value of those randomly chosen 7 asymptotic slopes to lie within the 1$\sigma$ ($0.50\pm0.13$), 2$\sigma$ ($0.50\pm0.26$) and 3$\sigma$ ($0.50\pm0.39$) ranges of the @Newman2013b results, respectively. In this comparison, we combine the constraints from the kinematic, strong lensing and weak lensing data as was done by @Newman2013b and, like them,


of the gNFW $r_s$ for the C-EAGLE clusters; the yellow stars with error bars are the gNFW $r_s$ values of the @Newman2013b clusters (estimated from the Appendix of @Newman2013a); and the red circles are the best-fit gNFW $r_s$ values for the C-EAGLE clusters from the sJ + lensing analysis. **Lower panel:** NFW scale radius as a function of M$_{200}$. The blue squares are the true values for the C-EAGLE clusters; the yellow stars are the values for the @Newman2013a clusters (from their Table 8). The cyan line is the mass-concentration relation for relaxed haloes at redshift 0.2 [@Dutton2014] , with the shaded region showing the corresponding 1-$\sigma$ scatter [@Neto2007].[]{data-label="fig:rs_plot"}](rs_NFW.png "fig:"){width="50.00000%"}

Importance of lensing constraints
---------------------------------

It is worth pointing out that the lensing data plays a crucial role in constraining the mass$\bar{\gamma}_{\rm dm}$ in the latter case is only about 3% smaller than in the standard case. These results indicate that the assumption of a constant $M^*/L$ is reasonable for the analysis of the inner dark matter density profiles in these massive clusters.

![Comparison of the joint constraints on the mean $\bar{\gamma}_{\rm dm}$ (at 44 kpc) from mock data constructed either assuming a constant ${M^*/L}$ (red) or the photometric model of @Trayford2015 (blue). Results are shown for sJ + lensing modelling, assuming in both cases that ${M^*/L}$ is constant. The yellow symbol and error bar show the observational result of @Newman2013b, while the cyan symbol and error bar correspond to the true C-EAGLE result. The values quoted in the legend are the most probable values of the mean $\bar{\gamma}_{\rm dm}$


axes are $a$, $b$, $c$ and $a\geq b\geq c$) are the square root of the ratios of the reduced inertia tensor eigenvalues. We iteratively calculate the reduced inertia tensor and the values of $q$ and $s$, deriving the triaxiality parameter from the stable $q$ and $s$ values.

If $s\ge0.9$, then the galaxy is close to spherical and, if $s\le0.9$, we can classify the shape into three categories: oblate for $T\le0.3$, prolate for $T\ge0.7$ and triaxial in between. All of our clusters have $s\le0.9$. From Fig. \[fig:shape\], we find that most of the cluster central galaxies have a prolate shape. Interestingly, although the shapes are not consistent with the assumption of the JAM or the sJ model, we do not find a correlation between the accuracy of the estimate of $\bar{\gamma}_{\rm               1.25                 0.69$^{+0.31}_{-0.40}$               11.58             11.61$^{+0.04}_{-0.05}$                 11.81                     11.73$^{+0.03}_{-0.03}$                0.41           0.23$^{+0.09}_{-0.07}$


   11.73             11.84$^{+0.09}_{-0.16}$                 12.02                     12.10$^{+0.03}_{-0.03}$                0.47           0.44$^{+0.18}_{-0.16}$
   CE-19                 1.95                      1.69$^{+0.10}_{-0.09}$    did not take the free money offered to it by the federal government to help expand Medicaid to more of its low-income citizens.[11] This decision also disproportionately disadvantaged Black citizens.[12]

Prior to the ACA's ban on gender rating, women in Alabama paid up to 53% more for the same coverage as men;[13] an ACA repeal is likely to bring back that coverage gap.

Given that a repeal of the ACA would also change payment structures and subsidies, 28,000 jobs could be lost in Alabama. When federal funding is cut, it creates a ripple effect that affects local and state revenue, thus creating losses in economic activity and employment.[14]

Under the ACA Repeal-and-Delay Strategy, Young Adults in Alabama Could Pay $922 More in 2018.[15]

Alabama does not allow undocumented immigrants to get drivers'


Madison can't be executed due to incompetence. The appellate court first sent the case back due to race-based jury selection and improper testimony. [33]

In 2015, an average of 417,943 households and 889,380 individuals received Supplemental Nutrition Assistance Program (SNAP, formerly called Food Stamps) benefits in a given month in Alabama.[35] In 2011, approximately 19% of the population of Alabama was receiving Supplemental Nutrition Assistance Program (SNAP, formerly called Food Stamps) benefits.[36] The average monthly benefit per Alabama household was $261 per household and $121 per person in 2016. [37]

In 2016, an average of 25,772 households, including 11,239 families and 20,315 children, received Temporary Assistance for Needy Families (TANF), which is direct financial assistance, in a given month. [38] The average monthly benefit for a single-parent with three childrenproperties. [102] The City of Birmingham was awarded a $400,000 community-wide assessment grant. The City of Tarrant was awarded a $200,000 cleanup grant for the Tarrant Industrial Complex. Both grants were issued through the EPA’s Brownfield Program. [103] EPA Administrator Scott Pruitt has called the Brownfield Program “essential” [104], and it does not appear to be targeted by the administration’s proposed cuts to EPA.

Alabama has the fourth-highest percentage of disabled people in America: 16.7% of Alabama's residents are disabled, compared with the national average of 12.6%.[2015 US Census American Community Survey, Table R1810]

Alabamans with disabilities have the fourth-lowest employment rate in the country, at 27.9%, compared to the national average of 34.9%. People without disabilities in Alabama have a 71% employment rate.[2015 US Census American Community Survey, Table


accumulation of massive to semi-massive sulphides to disseminated sulphide ore up to 12m thick.

Near Mine Exploration

A number of conceptual targets have been identified at Long and IGO’s intention is to drill these through FY19.

Care & Maintenance

IGO is actively maintaining the operation during care & maintenance to ensure its remains in a state of readiness for a number of options such as re-entry, exploration, exploitation and / or rehabilitation.

Whilst in care & maintenance, IGO will continue to dewater the underground mine, maintain surface and underground infrastructure, and undertake earthworks to ensure public safety and minimise environmental impacts.

Progressive Rehabilitation

IGO is also taking this opportunity to progressively rehabilitate some of the legacy landforms on the site including the old tailings storage facilities and waste (mullock) rock dump.can be due to the "enter" key or due to clicking of the mouse outside the row.

For #1 and #2 I have been trying with keydown events but not sure how to move the focus from one view to another.
For #3 I tried using the blur and focusout events but not very successful.
Any thoughts on how this can be achieved will be helpful.
Thanks

A:

As you are using marionete you can use event aggregator
and trigger events on the other views.
http://lostechies.com/derickbailey/category/backbone-eventbinder/
In this blog post Derick explains it better that I would.
Hope this helps


the remaining bonds can't be sold by February.

The northern Kentucky city of Williamstown in December issued taxable debt for affiliates of Answers in Genesis, a Christian nonprofit, data compiled by Bloomberg show.

Even though $26.5 million of securities have been sold, the project needs to sell at least $55 million in total to avoid triggering a redemption of all the bonds, Ken Ham, the nonprofit’s president, said in an e-mail to supporters yesterday. Without the proceeds, construction funding will fall short, he said.

“We still need those Ark supporters who weren’t able to purchase the Ark bonds at closing to prayerfully consider participating in a secondary bond delivery at the level they had indicated to us,” Ham said. “Will you please step out in faith with us?”

The problem with "Arkis in series with the metal-to-metal connection between the flanges, and minimizes the current across it. The distance from the main waveguide through the gap to the ditch is likewise one quarter of a wavelength in the E-plane. The gap thus forms a quarter-wave transformer, transforming the high impedance at the top of the ditch to a low (ideally zero) impedance at the broad wall of the waveguide.

Frequency dependence
Because the working of a choke connection depends on the wavelength, its impedance can be zero at at most one frequency within the operating band of the waveguide. However, by making the gap extremely narrow, and the choke ditch relatively wide, the input impedance can be kept small over a broad frequency band. For gap and ditch widths in a


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The program runs on more than one Windows versions so there is a lot of flexibility as far as getting things done isthe coded data block C2 with a respective associated puncturing data field. The puncturing by the puncturing device P is carried out in order to increase the data transmission rate. The punctured coded data block P (C1) and the punctured data block P (C2) are applied to inputs of the multiplexer, which subjects the data block X which is read in and the two punctured data blocks P(C1) and P(C2) to time-division multiplexing to form a transmission data block S.
The text below describes the exact manner of operation of the parallel-interlinked turbo coder based on the prior art, as shown in FIG. 2, using an example to illustrate the problem on which the invention is based. In this example, the length of the data frame is 5 bits.
From


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Catching problemstortured man's true vassals, who cry with the hope that the injured man may one day be delivered to them. The elder lady tells Jaufre that Taulat's next visit will be in eight days' time, so Jaufre departs, promising to return in eight days.

The Black Knight: 5170–5660
Jaufre comes across a hunger-stricken old lady sitting under a pine tree, who tries to bar Jaufre’s way, but he passes anyway. Approaching a chapel, he is stopped by a demonic black knight, who attacks him without cause. They fight all day and all night, until a hermit comes out of the chapel the following morning and dispels the demon. The hermit explains that the old lady had had a giant as a husband, who had wrought destruction across the land. When


Taulat's fate, he is condemned for seven years to undergo the same torture as he had inflicted on others.

Augier's Daughter: 6685–6923
Meanwhile, Jaufre arrives at Augier's castle with Augier's daughter. Augier, with his sons, comes out to meet Jaufre, lamenting at the loss of his daughter and not recognising her because she looks so beautiful on Jaufre's palfrey. Jaufre is sorry to hear of the loss of Augier's daughter, but presents him with the girl on his palfrey as a replacement. Augier recognises his daughter, and gives Jaufre a warm welcome. In spite of Augier's insistence that he should stay, Jaufre departs the following day for Brunissen’s castle, escorted part-way by Augier.

Brunissen: 6924–7978
Brunissen's seneschal, who had been sent off in search of Jaufre, meets Jaufre and Augier, and promisesin the fountain. Jaufre runs to her aid, tries to lift the lady out of the fountain with his lance, but fails. The young girl then pushes him into the fountain. Jaufre disappears underwater. Melian, Brunissen and Augier presume him to have drowned. They all despair and mourn Jaufre's death. Jaufre, however, is taken through the fountain to an underground world. The lady who had feigned drowning turns out to be the same one who had asked for Jaufre's help several days before, to no avail. In spite of the ruse, Jaufre promises to defend the lady's castle against the criminal, Felon d'Auberue. Felon arrives with a fascinating hunting bird. Jaufre is insulted by Felon, attacks him, and is victorious. Felon delivers himself up to Jaufre and the


work and the one who completed it" referred to in the explicit to the work. The laudatory passages to the King of Aragon on vv. 2616–2630 may be the demarcation where the second poet intervened to continue the tale. But none of the arguments are conclusive.

One clue for dating is the dedication of the work to the young King of Aragon (also the Count of Barcelona), who has been identified variously as Alfonso II (r. 1162–1196), Peter II (r. 1196–1213), or James I (r. 1213–1276). Depending on the scholar, the dates assigned to the work span the reigns of these three monarchs, anywhere from c. 1170 to 1225/1230, or even later. Against a later dating is the fact that James I did not really win his first battleromance may have been one of the sources that Chrétien de Troyes drew upon. But that prospect is discounted by the majority of scholars, who believe rather that Jaufre was a work by poet(s) who came afterwards and gained "intimate knowledge" Chrétien's works. The literary style also points to a later date, for instance, King Arthur is portrayed in somewhat negative light, and a "certain stiflement of adventures".

Texts and translations
There are two complete manuscripts of the text: Paris, Bibliothèque nationale, français 2164 (designated A), illustrated, dating from c. 1300; and Paris, Bibliothèque nationale, français 12571 (designated B), an early 14th-century exemplar by an Italian copyist. Five fragments have also survived.

Among modern editions, those that use ms. A as the base text include 's (1943), as well as