a shade more florid, a shade more defensive, and we know we are witnessing a moment of self-deceptive bluster. Between the rueful self-knowledge of the hero and the ironizing impulse of the author, no vanity goes unpunctured.

This is about more than contemporary sexual manners, and about more, even, than urban middle class status anxieties. Our American male novelists, I suspect, are worried about being unloved as writers—specifically by the female reader. This is the larger humiliation looming behind the many smaller fictional humiliations of their heroes, and we can see it in the way the characters’ rituals of self-loathing are tacitly performed for the benefit of an imagined female audience.

In a 1998 review of John Updike’s novel Toward the End of Time, David Foster Wallace identified Updike, alongthirty-seven and recently lost his academic teaching job after an affair with a student, has written a commercial potboiler-type screenplay about a persecuted academic that he’s hoping will make him a lot of money. As she’s making her awkward exit from his apartment and their relationship, Julia, who works for a film producer, breaks the news to Chip that his screenplay is very, very bad. Her critique is wide-ranging (there is, for instance, the problem that the screenplay starts with a six-page lecture on “the anxieties of the phallus” in Tudor drama), but she emphasizes the “creepy” way that Chip keeps mentioning the female lead’s breasts. “For a woman reading it,” she says, “it’s sort of like the poultry department. Breast, breast, breast, thigh, leg.”

Chip starts to defend


attend training meetings and to obtain their certification in Child CPR/First Aid/AED. All employees must pass a pre-employment background check and drug screen to be hired. Camper to counselor ratio is always 1:10. Participation Summer Recreation Day Camp activities are designed with youth in mind. We encourage all campers to participate in, or at least try, all activities.

3 SUMMER REC. POLICIES, PROCEDURES, AND GENERAL INFORMATION Please read this handbook thoroughly before your child starts camp. Where is Camp Held? The primary location for Summer Rec. is the Republic Activities Building (next to the Republic Community Center). Important Numbers 1. Summer Rec. Office: Summer Rec. Cell Phone: (only carried on field trips / SS pick-up) 3. Republic Community Center: Please try these numbers in the order that they arebe considered a Late Payment. Each week begins on Monday morning at 6:30 a.m. (unless the week begins on Tuesday due to holidays). All payments for the next week must be received by Friday at 6:00 p.m. There will be an additional $10.00 charge per household for all late payments; this will be added to the weekly camp fee. Refunds and Credits Refunds will not be considered without written documentation requesting a refund. All refund requests must be submitted to a camp director. All refund requests must be submitted before the week you need a refund for (no later than 6:30 a.m. on the first day of the week). If a week of camp has already started, no refunds will be considered for that week. Payments may be


program. If you have additional

BREA SUMMER DAY CAMP! June 18 August 24, 2018 Dear Parents of Day Camp Participant: The City of Brea proudly announces the beginning of the 2018 Summer Day Camp Program. This year s program will take place

Tualatin Hills Nature Center Parent Handbook Summer Camp 2018 Thank you for choosing us for your child s summer camp experience. Please read through this handbook and discuss it with your child so that

THE RAVENS GUIDE TO SUMMER CAMP 2016 WELCOME TO RAVENS SUMMER CAMPS! For the next week your child will participate in a wide range of exciting sports and activities at Carleton Sports Camps. You will learn

Parent Information for Camp Chai 2017 Program/On-Site Director: Emmy Wagner Sessions 1 and 2 of Camp Chai will be helddella comunicazione, Milano SugarCo, 1982 (ma 1951); Id., Empire and Communications, Toronto, Toronto University Press, 1972; E. A. Havelock: Cultura orale e civiltà della scrittura. Da Omero a Platone, Roma-Bari, Laterza, 1973 (ma 1963); Id., Dalla A alla Z. Le origini della civiltà della scrittura in Occidente, Genova, Il melangolo, 1987 (ma 1976); Id., La musa impara a scrivere. Riflessioni sull'oralità e l'alfabetismo dall'antichità al giorno d'oggi, Roma-Bari, Laterza, 1987 (ma 1986); W. J. Ong: Oralità e scrittura. Le tecnologie della parola, Bologna, Il Mulino, 1986 (ma 1982). Per un'articolata rassegna di queste posizioni, cfr. l'ottimo A. Abruzzese-A. Miconi, Zapping. Sociologia dell'esperienza televisiva, cit.; in part. pp. 87-111. 18 Come è sin troppo chiaro, ci stiamo criticamente riferendo a P. Lévy, L'intelligenza collettiva. Per un'antropologia del cyberspazio, Milano,


claimed[@jaramillo2014origins]. Different models for the origin of the MIT have been put forward, based on either positive or negative charge transfer as responsible for the insulating state [@zaanen1985band; @mizokawa1991origin; @alonso2000room; @khomskii2001unusual; @mazin2007charge; @medarde2009charge; @park2012site; @johnston2014charge; @varignon2017complete]. The negative charge transfer model supports the bond disproportionation picture and is strongly supported by recent experiments [@bisogni2016ground; @green2016bond; @shamblin2018experimental]. Independent from the exact microscopic picture, the origin of the MIT is a cooperative lattice distortion that reduces the symmetry from a high-temperature orthorhombic phase to a low-temperature monoclinic phase, involving two Ni sites, with the associated need for cooperative accommodation of different Ni-O bond-lengths [@mercy2017structurally]. Remarkably, it has been reported that eliminating the MIT in nickelates by orbital engineering would give rise to a superconducting state [@hansmann2009turning], with a very recentK to 400 K) can be well described with a linear temperature dependence (*n*=1.00$\pm$ 0.01), independent of film thickness. This temperature dependence has been observed in other systems, ranging from cuprates to heavy fermions, in spite of their different mechanisms of electron scattering [@bruin2013similarity]. What they have in common, however, is a constant scattering rate per kelvin ($\approx k_B/\hbar$), indicating that the excitations responsible for scattering are governed only by temperature. On the other hand, in the case of NNO/STO films (Fig. \[fig:resistivity\](d)), the temperature-resistivity scaling of films with different thickness deviates from linearity, showing the departure from this intrinsic mechanism. The values of *n* and A-coefficients in both NNO/LAO and NNO/STO systems are shown, as a function of thickness, in Fig. \[fig:fitparameters\](a) (for details on the determination


of *n*, see Fig. S2 in SM). Interestingly, *n* shows a clear evolution with thickness in the NNO/STO films: *n* decreases with increasing NNO/STO film thickness from a value of *n*= 3.00$\pm$ 0.05 for a 5 nm film to an apparent linear dependence (*n*= 1.01$\pm$ 0.01) for the thickest film (40 nm). To understand this behaviour we turn to an in-depth structural characterization of the films.

Figures \[fig:XRD\](a)-(b) show the diffraction patterns for films grown on LAO and STO, respectively. The presence of Laue fringes indicates the high quality of the interfaces. The different sign of the epitaxial strain on the two substrates can be assessed by the different relative positions of the film and substrate peaks. Reciprocal space maps (RSM) around the (103)~c~ peaks, are shown in Fig.peak of bulk NNO.[]{data-label="fig:XRD"}](F3.JPG){width="50.00000%"}

In order to shed light into this behaviour, we performed scanning transmission electron microscopy (STEM) on the films. Cross-sectional specimens of the films were studied by atomic resolution STEM (for experimental details, see SM). The high-angle annular dark-field (HAADF) STEM image shown in Fig. \[fig:TEM1\](a) evidences the epitaxial, cube-on-cube growth of a 5 nm thick NNO film on a LAO substrate, with a flat, atomically sharp interface. No defects or misfit dislocations are observed. The strain state of the films was determined by geometrical phase analysis (GPA) of the HAADF images, the deformation of the in-plane lattice parameter of the film respect to the substrate ($\varepsilon_{xx}$) is depicted in Fig. \[fig:TEM1\](b). $\varepsilon_{xx}$ is virtually zero across the 5 nm NNO film, showing a good in-plane


are deposited atomic-layer by atomic-layer.

Cross-sectional specimens of the films were prepared and studied by scanning transmission electron microscopy (STEM) on a probe corrected FEI Titan 60–300 microscope equipped with a high-brightness field emission gun (X-FEG) and a CEOS aberration corrector for the condenser system. This microscope was operated at 300 kV. High angle annular dark field (HAADF) STEM images were acquired with a convergence angle of 25 mrad and a probe size below 1 Å. The strain state of the films was determined by geometrical phase analysis (GPA) of these HAADF images.

Transport properties were measured between 5 K to 400 K by the van der Pauw method in a Quantum Design Physical Property Measurement System (PPMS), using a Keithley 237 current source and a Agilent 3458A multimeter.

Extracting thethen found the 42 corresponding English Wikipedia articles for each disease (some, such as "child behavioral disorders" referred to both "ADHD" and "conduct disorder"). Traffic on these articles was compared against that on a broader set of Wikipedia articles corresponding to diseases, as identified by the presence of a standardized template ("infobox") that concisely summarized disease metadata (eg, a condition's index in various disease databases).

Quantity/Characteristics of Wikipedia's Medical Contributors
------------------------------------------------------------

Already leveraged for categories and language links, the Wikimedia API also permits one to crawl version histories to gather metadata about an article's editors. Aggregating this across all medical articles (or just those of a particular language), we were able to plot participation at various thresholds. In particular, we identified 274 contributors who made more than 250 edits to medical


are often less ambiguous, but still require a bilingual speaker who is familiar with Wikipedia syntax.

Although subjectivity might shift these bounds slightly, more articles have likely never been considered in these contexts, either because they are undiscovered entirely or they are too emergent, tangential, or unpopular to draw the attention of the editors who typically make category and interlanguage annotations. Although usually quickly restored \[[@ref25]\], "vandals" also sometimes destroy tags or links with malicious intent.

Following the very nature of collaborative work, it is our subjective experience that "major" topics are more likely to be correctly tagged and linked than more obscure ones. Thus, tagging and linking inaccuracies likely have a greater impact on article quantity measurements than readership totals. In particular, categorization omissions could be estimated by searchingEnglish Wikipedia using a database of terms such as the International Classification of Disease (ICD-10) and verifying that corresponding articles have been appropriately tagged. We leave this as a topic for future research.

Lastly, our analysis used tagged English articles as the starting point for interlanguage link discovery. A medical topic that did not have a corresponding English article version would not be included in our analysis.

### Citations Supporting Wikipedia's Medical Content

Wikipedia strives for verifiable content rather than the less agreeable notion of absolute "truth." As such, information drawn from reputable sources upholds the notability and verifiability requirements that Wikipedia promotes.

In this work, we quantify the number of references (and highlight some particularly well-reputed sources) as a proxy for reliability. We recognize that the number of references is just


National Institutes of Health (NIH) and Wikipedia often see their content integrated directly into Google search results and these sources often have high search-engine ranking \[[@ref35]\].

### Quantity/Characteristics of Wikipedia's Medical Contributors

Our survey to medical editors had a response rate of approximately 43%. This raises the concern that those with the time and willingness to complete the questionnaire are somehow nonrepresentative. Although approximately half of recipients primarily edit a non-English Wikipedia, our survey was available only in English, potentially limiting and biasing the response pool. Our validation question ("Did you receive a barnstar?") also takes respondents at their word in addition to trusting the feedback received for all other questions.

We identified 4 Internet Protocol (IP) accounts that made more than 250 edits assuming that those IP addresses are staticallyquite similar to our findings, which additionally considered non-English editors.

Conclusions
-----------

### Amount of Wikipedia Medical Content

Although Wikipedia has a tremendous amount of medical content, it is primarily concentrated in English and a few major European languages. As a user-generated website, this reflects the populations that are willing and able to contribute. Wikipedia's distribution of content by language, however, better matches global language popularity than the Internet does as a whole. Additionally there are ongoing efforts to improve Wikipedia's medical coverage in non-English languages via a partnership with the not-for-profit Translators Without Borders.

### Citations Supporting Wikipedia's Medical Content

Wikipedia is relatively well referenced and by this marker is becoming increasingly reliable over time. Encouragingly, references to high-quality sources, such as The Cochrane Collaboration, are rising at a greater rate than references


India vs Australia 2nd T20I Live Streaming: When and Where to Watch, Live Coverage on TV and Online

cricket

Updated: Feb 27, 2019 08:32 IST

After conceding the first match in Visakhapatnam, Virat Kohli and team would be keen to hit back and draw the series with a win at the M Chinnaswamy Stadium in Bengaluru. India could make a few changes to their team and on a pitch, which assists stroke-making, a far more attacking bowling option could be opted for.

Apart from KL Rahul and MS Dhoni, the India batsmen were unable to get going against the Australian pacers and when it came to the bowling department, almost all of them struggled with the exception of Jasprit Bumrah. With the morale taking a bit of a hit from the loss,Benetton’s ads are well known for promoting diversity, usually cultural diversity. This has been noted, studied and also parodied, such as in Family Guy when Stewie is adopted, he remarks that he’s been placed in a Benetton ad. However, Benetton’s latest ad campaign is definitely their most shocking yet.

Their new ad campaign features various world leaders, well, kissing each other, and usually they are leaders who have not been the best friends. The Vatican has already been outraged by the ad that includes Pope Benedict XVI kissing a top Egyptian imam on the lips. See the full shocking gallery in this post.


balanced by 2015-2016 through raising revenues and saving smartly, as opposed to the austerity approach of balancing the budget by 2013-2014 to coincide with an election cycle.

Harsh cuts to education

Dexter's cuts to education have been particularly harsh. The Dexter government will be cutting post-secondary education up to ten per cent, while tuition for full-time undergraduate students rose by 5 per cent in 2012 according to Statistics Canada.

Nova Scotia's university students are charged with the second highest graduate and third highest undergraduate tuition fees in Canada, despite a three year cap on tuition. Nova Scotia students graduate with an average debt of $31,000. At the secondary and elementary school levels, more than 150 teachers and 40 educational workers and support staff will lose their jobs, with larger class sizesprojections they put together would also be poor would at least be consistent." The report found that expenditures could fall by $75 million if market projections are off by 10 per cent or fewer, and the financial rewards would fall by $377 million if the market projections are off by 50 per cent or less. The report also indicated that Dexter refused Lapointe's recommendation that a third-party conclude whether a new convention centre was needed. Given Dexter's penchant for handing out tax payer dollars to, and doing favours for corporate interests, this seems like the case once again.

No democratic reform on the agenda

Furthermore, the Dexter government hasn't acted on legislating proportional representation, which Jack Layton (and now Tom Mulcair) made a high priority for the NDP. While the


a versatile sauce. It not only goes well with cooked steamed chicken, I have also tried brushing it on raw food (such as chicken thighs) and steam with D.O.M liquor with great results. I also frequently add it to my salads for that extra oomph.The present invention relates to bias circuits, and more particularly to an interactive bias circuit for reading non-volatile memory elements.
Many electronic systems include memory devices. The memory devices are often used to store critical information that is needed by the electronic system. In some instances it is necessary for the memory device to provide non-volatile storage. Non-volatile memories allow for information to be permanently or semi-permanently stored such that removing power from the memory does not destroy the stored information. Example non-volatile memory devices include Erasable Programmable Read Only Memory (EPROM) as well as others.
The trend in the electronics industry is to reduce overall power consumption in electronic systems. This trend is largely due to the proliferation of battery powered electronic systems. In an effort to preserve battery


on script for a feature. The short film would act like a prequel to the feature film.

“We had the idea for the feature. We thought to raise funds or try to get feature interested to do a short film, with a story sort of like a subplot to the feature,” he explained.

The ultimate hope is that someone at MDIFF, or any might see it and be willing to fund the feature for Indiendo Productions.

This is the second time Indiendo Productions had a film shown at MDIFF. In the 2011, another short film, “Machine Room,” was shown.

Derrick said their mission as filmmakers is to make the audience think.

“All of our films, I believe, are pretty thought-provoking. That’s what I’d like to believe,” he said. “That’s the reason we doprocessor to use the least used reagent within that type, which (as the least used) is the cleanest available. The central control system can also output information regarding available wax and reagents loaded in the tissue processor, so that operator of such tissue processor will be able to timely refill wax and reagents when necessary. Specifically, the central control system in one embodiment is arranged to detect a need for replacement of wax or reagent in a wax or reagent container, according to operational limits that are predetermined or otherwise specified by the operator, and to communicate such need to the operator through an output device. Such output device may include any audio or visual display known in the art.
The reagent management program, in a specific embodiment of


get a lot of girls in here." "You know?" "Listen, I'm just here to deliver a message." "You're in danger." "You need to get out of here immediately." "Victor." "What?" " Oh, come on." "A hot blonde in a comic book store?" "Please." "Victor sent you, right?" "This is payback for the whole birthday thing, right?" "Wait, let me guess." "Is this all gonna end with you giving me like a lap dance or something?" "No!" "You have to listen to me, all right?" "This is not a joke." "There are people out there who are after you." "They will come in here and take you away." "Yeah!" "In here?" "Oh, come on." "You gotta do a better job convincing me." "Your life is in danger." "Move." "Now.""Move." "Now." "You wanna tell me what the hell is going on?" "There's a man in here." "He's looking for you," "And he's very, very dangerous." "Do you have your car here?" "Yeah, yeah, but it's out back." "Alex working today?" "Come on." "Alex Woolsley." "I'm from the County Clerk's Office." "Afraid we have a situation with some outstanding parking violations." "Um, would you rather just go talk outside?" "Sorry." "Uh, this isn't a really good time." "Is it important?" "Look, Dad, I just" "I was thinking about what happened this morning..." "Uh..." "Uh, sweetheart, I'm gonna have to call you back." "Go!" "We're gonna need a team down here." "Come on." "Come on." "Come on." "Come on." "Hello." "Hi." " My name is Ando." "I'm sorry." "I'm


him." "What kind of man sells his own son?" "Why would he even tell you something like that?" "Maybe I reminded him of you." "Oh, my God." "I know." "It looks harsh." "We tried insulated gloves, but she shattered right through them." "The constant heat is to ensure..." " Abby." "This is Tracy Strauss." "You know her." "She used to lobby for a defense contractor." "Abby, they won't let me out of here." "You have to do something." "What is this insanity?" "This woman is extremely dangerous." "Abby, he's lying." "You know me." "This woman is Tracy Strauss," "And you have her shackled to a chair." "That's why we need better funding." "Funding?" "I am shutting this operation down today, and then I'm going to the A.G.'s Officelips. I also want long lasting lip colors. This is very nice! Thanks!

Vivien

My pick would be Ultra HD Lip Lacquer in Pink Ruby. A bright pink shade which instantly lit up the face. Is neither fiery red nor sweet pink, somewhere in between which bring out a confident, attractive, fun character. The silver sparkles make it even more special, subtle yet good for day and night. Thank you for holding the giveaway BunBun! 😀


Introduction
============

Dengue is an acute infectious disease common to tropical and subtropical regions. Dengue viruses are transmitted by *Aedes* mosquitoes, mainly *Aedes aegypti* and *Aedes albopictus* ([@r39]). Globally, the World Health Organization has estimated that there are 50--100 million dengue infections per year ([@r38]), although more recent estimates have elevated this figure to 390 million, of which \~96 million are symptomatic ([@r4]). Dengue infection in humans is mostly self-limiting---although antiviral drugs are under development ([@r28]; [@r37])---but may require hospital admission, and the more severe manifestations of dengue may lead to death ([@r32]). Case fatality rates of dengue fever and severe dengue vary from 0--5% to 3--5% ([@r18]).

The city-state of Singapore, which lies approximately 130 km north of the equator, has a tropical rainforest climate in the Köppen--Geiger climate classificationweeks in the past) of nonseasonal and seasonal differencing in the time series (between successive values, used to reduce the effects of nonstationarity of the time series), *p* and *P* are the autoregressive (AR) terms, and *q* and *Q* are the moving average terms. SARIMA models can vary from very simple---for instance, a nonseasonal AR1 model in which the dependent variable is regressed upon itself (*y~t~* = β~0~ + β~1~ *y~t~*  ~-- 1~ + ε*~t~*)---to very complex, where the dependent variable depends on several past weeks, on moving averages of past weeks' data, and on recurrent seasonal factors, in the present case, 52 weeks ago. The values of (*p, d, q, P, D,* and *Q*) with the lowest Akaike information criterion (AIC) during model training are selected for the


albopictus*, and the presence of *Ae. aegypti* is necessary for sustained transmission in any neighborhood. The breeding percentage for week *t*, *BP~t~*, was calculated from the weekly number of *Aedes* mosquito breeding sites recorded during ground inspections carried out by NEA using the following formula:

![](ehp.1509981.e003.jpg)

,

where *N~aegypti~*(*t*) and *N~total~*(*t*) are the number of breeding sites containing only *Ae. aegypti* or containing either *Ae. aegypti* or *Ae*. *albopictus*, respectively, in week *t*. This index has been found to have a high correlation with dengue cases (unpublished data) and to be negatively correlated in space with chikungunya cases, for which *Ae. albopictus* is the more competent vector ([@r33]).

***Trend and seasonality data.*** In addition to climatic factors, dengue is affected by other factors such as changes to vector control and circulating serotypes.step-down linear regression and SARIMA are represented by vertical bars, filled orange polygons, and filled blue polygons, respectively. The MAPE degraded more slowly over time under the LASSO approach, with an increase from 17% error forecasting at 1 week to 24% error forecasting at 3 months, although the LASSO approach yielded comparable accuracy to those of step-down linear regression and SARIMA for the first 2 weeks. (*B*) Coverage of LASSO, step-down LR and SARIMA. For each forecast window period, the percentage coverage was calculated using the number of observations that fell within the 95% interval derived by overlaying the estimated error distribution on top of the forecast. The dashed line represents the nominal coverage of 95%.](ehp.1509981.g004){#f4}

Interpretation of climatic and other factors was difficult because the strength of their association varied between


avoid over-fitting, and improve out-of-sample predictive accuracy ([@r22]; [@r49]). By shrinking regression coefficients of less importance to or towards zero and thereby retaining only the most important predictors, LASSO is able to obtain good interpretability and stability ([@r49]).

Although LASSO is a well-established methodology that is frequently used in bioinformatics and other big-data applications ([@r16]; [@r41]; [@r47]), there are few applications of this method in epidemiology (for instance, [@r46]) or in neglected tropical diseases. In this paper, we report the use of LASSO in forecasting an endemic and high-burden disease---dengue---in Singapore, which, by virtue of its location near the equator and concomitant lack of seasonality, experiences unpredictable outbreaks above the usual endemic level. The LASSO methodology has several advantages over traditional approaches: *a*) Model selection is rapid (approximately 2the country. Taken as a whole it
is not at all a flat district, and it has enough ups and downs and variety
of scenery to suit any taste, but it is practically barren of hills
presenting any real difficulty to a car of moderate power. So, in this
volume, it is not necessary or possible to indicate any very serious
gradients to be encountered on this journey or on that. It remains only,
after a word of thanks to the friends who have lent their company and their
cars, to add that every chapter is a faithful narrative of tours undertaken
or of journeys made, together with an account of the associations and
memories appropriate to the places visited, and that, to save breaking the
flow of the text, an analysis showing the route taken in each


Pickwick, doubts whether he
was burglar or lunatic, imprisonment in the Clothes Closet, rescue and
explanation by Mr. Wardle, rheumatics of Mr. Pickwick, and, last of all,
the Parish Clerk's tale. These things are not history of course, "which
there never war no sich a person" as Mr. Pickwick, but they are
imperishable and essential truths none the less, and the _Pickwick Papers_
are a possession of Bury St. Edmunds at least equal in commercial value to
all the legends of St. Edmund, King and Martyr. So much for Bury on this
occasion. We shall see it again, and foregather this time at the "Angel."

We left the hotel, to find cold and windless darkness in full possession.
It was my first experience of driving in a motor-car on a dark night for
any considerable distance through an unknownthe ancient "Angel" with mighty satisfaction and to the remarkably
small minishing of my store of sovereigns. On a second visit to Ipswich I
was hospitably entertained by a local gentleman at the "Crown and Anchor,"
because he thought it was the best hotel in Ipswich, and behold the fare
was very good! By the same gentleman I was introduced to oysters, in a
little shop near the Butter Market, the best I ever ate, and to hand-made
gloves in a little shop hard by which have motored many a merry mile since
then. There need be no hesitation in advertising them. They are made by a
widow and her daughter out of soft and strong Cape leather, and with them,
it is to be feared, the industry will die, since apprentices will not come
to them in


Andrew's Church; and, after dinner at the "Maid's
Head," the vicar of St. Peter's, Permountergate, read a paper on the parish
records. Just a few of the entries it is impossible to resist, for they are
of imperishable interest.

"1798. October 19th. Form of Prayer on the victory obtained by Admiral Sir
Horatio Nelson over the French fleet off the Nile, 1st August /6."

"Nov. 12th. Form of prayer for general thanksgiving on 29 November 1/".

"1805. December 5th. Paid for a form of Prayer and Proclamation on account
of the late glorious victory over the combined fleets of France and Spain
by Lord Viscount Nelson off Cape Trafalgar on 21st October, 1/".

No bells were rung in Norfolk that day, for the calamity of Nelson's heroic
death saddened the heart of every man in his native county. Butempty road, and there was no chance of his coming upon
them unawares. Partridges we saw galore, cock-pheasants strutting on the
ploughland, confident that they were safe from the gun by law till the next
October, and probably knowing quite well--for there are few things a wily
old cock-pheasant does not know--that there would be no serious danger,
away from boundary hedges, until the leaf was clear in November. Less
handsome than the cock-pheasants, but more interesting, because less
familiar to my eyes, were the hooded crows, in their sober suits of
drab-grey and glossy black, walking about in perfect amity with the
pheasants. This bird is a grey mystery. In shape and dimensions he is
identical with the carrion crow; carrion crows and hoodies (or Royston
crows) will interbreed on occasion; their nests and eggs are of identical
situation,


of England; they are far and away the most
exciting events in the history of Norwich, and, since they cannot be dealt
with fully here, they are best passed over with this slight mention.

At Wymondham is, or was, an old house having a very curious inscription,
"_Nec mihi glis servus, nec hospes hirudo_," which is not quite free from
difficulty even as it stands, for a verb is left to be understood, and it
may be "_sit_" or "_est_." In the one case the guest hopes, in the other
the house boasts, the servant to be no dormouse and the host no leech.
Things were worse when somebody read _hirudo_ as _hirundo_, though one
might make attractive translations of that too. But we cannot linger over
that when we are close to the scene of a tragedya spacious room,
if its floor area alone was considered; but of course the ceiling was very
low, and the dark beams supporting it were still lower. It would have
suited Hannah More, who loved ceilings you could touch as you stood, but it
lacked the bishops she required as an accompaniment. At least it lacked
them then. One great bed was of carved oak, relieved with gilding; another
made no impression on my memory. But the long and low windows, the shining
planks of the ancient floor, which boasted its own hills and valleys,
<DW72>s and hollows, and the cleanliness and brightness of everything made a
very vivid and pleasant impression. Queen Elizabeth may not have slept in
that chamber or in the "Maid's Head" at all when she visited Norwich in
1578 and weird pageants were displayed


of English peasants, their simple pedigrees
never kept because they seemed to be of no moment, which are probably far
older in the land than any noble family, so there are, in all human
probability, thorn trees more ancient by far than the oldest oak. They have
survived, or at any rate they give the impression that they have survived,
which is what really matters, longer than the oaks for the same reasons
which have led to the survival of the rustic families of men. As peasants
were left alone when peers went to Tower Hill, so thorn trees have been
passed unscathed by storms which have torn off the limbs of oaks or laid
them prostrate on the ground, have been spared by the woodcutter in search
of his raw material for England's wooden walls. They wereanother. At Harwich it
has, we all hope, been stopped, but all the world knows the mischief which
has been wrought south of the estuary of the Thames by the gradual process
of accretion converting thriving ports into meaningless inland places. What
all the world does not realize, and what our most practised engineers in
this kind apprehend, without pretending to comprehend fully, is the
unforetellable character of the results that will follow from every attempt
to interfere with these mysterious processes of nature which takes the form
of opposing an obstacle to the sweep of the tide. Thus to build a groyne or
a sea wall, to say to the sea in effect, "Thou hast taken so much, but thou
shalt take no more," is hardly likely to produce any injurious result. On
the other hand, to stretch


and
     an awkward rider--Rules of conduct in such
     cases--Through Braintree (remarks postponed) to Great
     Dunmow--Little Dunmow the true _locus
     classicus_--Leland and the Flitch--Far-fetched theories
     and an obvious explanation--The heart of the forest
     country--The old forest included Epping, Hainault, and
     Hatfield Forests--Hainault restored--Hardships of old
     forest law--Dunmow to Takeley--Hatfield Broad Oak and
     Heath--A view of hounds--High Ongar, Epping, and
     London, reversing original order--The drive reviewed.

Next morning, in a tearing wind, full of the promise of rain, we took a
road running as nearly N.N.E. as might be, making for thewords as applied to things is changed
when the country passes from an unsettled to a settled state, just as,
according to one of the Greeks, it is changed in revolutionary times.
"Forest" in old times denoted a district and, in respect of that district,
connoted a wicked restriction of public rights, or of rights which, to our
mind, ought to have been public. "Forest" now means a district in which the
public have abundant liberty, limited only by consideration for the rights
of all, and the rights of the Crown in relation to it hardly come into
account. Every remaining forest, whatsoever its governance may be, is a
treasure-house for the naturalist, a sanctuary for wild birds and beasts, a
place to be prized above measure since, in it, the dwellers in our
congested islands may walk face


within
limits which grow wider every year, when one is motoring for pleasure. The
essential things were that we took breakfast at a reasonable time and at
leisure in Felixstowe, went by characteristic cross-country routes to
Woodbridge and to Ipswich, strolled through Ipswich and shopped and
lingered over luncheon, took tea at ease in Great Dunmow, explored many
pleasant byways between it and London, and were back in London in plenty of
time to dine and to go to a first night at the theatre, and not in the
least too tired to do both with enjoyment. That is the new kind of pleasure
which the motor-car has rendered possible, and it is a very real and
genuine one.

CHAPTER VII

LATE SUMMER. COLCHESTER AND EASTWARDS

     Modern motoring and lack of sensational
    before it could be
realized, and certainly worth realizing by any easy-going student of human
nature.

My expeditions to Clacton-on-Sea were not taken by me in the capacity of
motorist simply; indeed, the first of them was made on a bicycle, and the
others, for there were several more to follow, in a car, when my knowledge
of motoring was embryonic. Yet I found in Clacton-on-Sea one of that
peculiar class of places which he who follows what may be called public
motoring learns to know through the motor-car, and would certainly not have
learned to know in any other way. Blackpool is another such place, visited
because in several successive years it has broken out into "speed trials,"
and Douglas in the Isle of Man is another, to which motorists go by reason
of the Tourist Trophy Race. Blackpool


prescient. The will
made in 1584 was proved in October 1585.

So thoroughly comfortable were the people of Long Melford in the days of
old that the temptation to mention the fact that a "Long Melford" was once
a name for a purse is irresistible, because the conjunction is so
appropriate. The temptation ought, perhaps, to be resisted because,
although the fact has been read and remembered, it appears to be unfamiliar
to Suffolk natives, and the source of information cannot be traced. It has
eluded fairly diligent search; but the fact has certainly been noticed
since this book was undertaken. I can remember no more than that it was a
purse of some peculiar make; and it would seem fairly safe to imply that it
was of capacious dimensions. Still, as the inscriptions already mentioned
show, those long purseswithout an eager
hope that the farmers encountered in June, 1897, saddened by disaster but
dauntless in the resolve to go on fighting against fate, have had, so many
of them as survive, the reward of renewed prosperity.

We ought to have stopped at Margaretting on our way to Ingatestone, with
the special object of inspecting the church, with its tower and spire
composed entirely of timber, the kind of structure which can be seen in
East Anglia only; but after all our next objective after Ingatestone is
Maldon, and the best way of reaching it is to go back on our own wheelmarks
so far as Margaretting, halt there for a few minutes, and then turn to the
right for Galleywood Common and Maldon. On this piece of road the motorist
will find a variation of levels and


such as the merely rushing motorist
would eschew. Not only were they narrow and exceeding crooked, they were
also very wet and greasy, so that a moderate pace would have been
compulsory in any circumstances. Still, if any rational motorists will take
this little drive in a leisurely way, they will agree, as they bowl along
the few miles of good high-road between Heckford Bridge and Colchester,
that it is exceeding pleasant and well worthy to be taken.

CHAPTER IX--(_continued_)

COLCHESTER TO THE EXTRAORDINARY "DENE-HOLES" AT GRAYS, ESSEX

     Early rising a mistake--Fine weather and misty
     mornings--Bound for Grays, near Tilbury--To
     Chelmsford--Great Baddow and Clare College,
     Cambridge--Galleywood Common--A wide
     prospect--Billericay--Origin of name an enigma--Arthur
   The position of the hotel,
looking down from a commanding height on town and sea, was perfect for
prospect and for bracing air; the golf-links, close by, were an undeniable
attraction to the large army of men and women who have yielded to the
seductions of that most fascinating game. It would have been unreasonable
to expect low charges; but all the same, the contrast between this bill and
that paid at Bury was a little stronger than it ought to be in a
well-regulated country. Other things were not so immediately obvious, since
for some it was the wrong season, and others were hidden in pleasant and
well-remembered books. We were in the heart of Poppyland, concerning which
Mr. Clement Scott and others raved, but it was too soon for the
poppies--poor Dan Leno's "Red, Red, Poppies," now


much of the land and, by enclosing,
cultivating and planting, had practically made it. It was part of the
fitness of things that a "mansion of almost peerless magnificence, as far
as its noble proportions, its gorgeous decorations, and its art and
literary treasures" were concerned, should be built out of bricks baked
out of Norfolk earth. The Hall stands in a spacious but level park, and a
glimpse of it may be had from the road. In the middle is a great
quadrangular block having, at each angle, a wing, 70 ft. by 60 ft.,
connected with the central block by a corridor. The wings are: the
stranger's wing, the family wing, the chapel wing, and the kitchen wing.
The library and the MSS. rooms are in the family wing; the gallery of
statues and the state apartmentsis not at all eager to pry into the houses of other and
greater men.

Who were these Cokes who attained so much magnificence? That is a natural
question. The name is first traceable in a deed of 1206, referring to a
Coke of Didlington. From him descended Edward Coke, the commentator on
Littleton, who was Attorney-General, Speaker of the House of Commons, and
Chief Justice of the King's Bench in 1613. Oddly enough, from our modern
point of view, it was after this that he was elected member for
Buckinghamshire, and drafted and moved the Petition of Rights. No doubt he
made a great deal of money himself; he acquired more by marrying first one
of the Pastons, and after her death, the Lady Elizabeth Cecil, daughter of
the first Earl of Exeter. Such was the real founder


with the
names of two men, each exceptionally worldly, each in his own singular way,
and with that of one remarkably eccentric. Houghton Hall was built by Sir
Robert Walpole from the designs of Colin Campbell, while the former was
Prime Minister, and Ripley, say Messrs. Timbs and Gunn (who speak with
authority), undoubtedly improved on Colin Campbell. Pope, it is true,
wrote:--

    Heaven visits with a taste the wealthy fool,
    And needs no rod but Ripley with a rule.

    *...*...*...*

    So Ripley, till his destined space is filled,
    Heaps bricks on bricks and fancies 'tis to build.

Pope, always bitter and not a little of a snob, was hardly likely to have a
good word to say for an architectbecause they can safely rely on a
regular influx of travellers, principally English, German, and American. "I
can never tell," says Boniface, "how many will want dinner on any day.
Whether five come or fifty, all expect dinner; I must always be prepared
for them"--very often he is sadly unprepared--"and my prices do not do much
more than cover my expenses. Many a beautiful joint have I provided, for I
never buy anything but the very best, that has had to be thrown away."
Quote to him hotels abroad, such as we all know, where guests are taken in
_en pension_, and fed fairly well, at from six to nine francs a day, or put
it at 5s. to 7s. 6d. to simplify matters, and, while it is plain that he
does not really believe you, he will


vanishing result appears in [@GR70]. We prove an analogous result for semi-rational singularities. The definition of semi-rationality requires that the choice of a semi-resolution is immaterial. This also has been established in the projective case in [@Berq14]. The analogous result for quasi-projective varieties is settled here. Semi-rational surface singularities have also been studied in [@vS87].

[Introduction]{} Demi-normal varieties arise in several contexts. These are varieties $X$ with properties $S_2$, $G_1$, and seminormality (SN). Equivalently, $X$ has an open subvariety $U$ such that the complement of $U$ has codimension at least two in $X$, and the only singularities in $U$ are (analytically) double normal crossings. In other words, at singular closed points $x$ in $U$, the completion $\hat{\mathcal{O}_{X,x}}$ is isomorphic to $k[[x_1, \ldots, x_n]]/(x_1x_2).$

A primary example is that of aare characteristics of the seminormalization of a reduced ring.

Our second construction is that of $S_2$-ification. As the name suggests, we wish to construct a finite ring extension $A \hookrightarrow B$ such that $B$ is $S_2$ as a ring. Here $A$ is reduced and of finite type over a field $k$. For this construction, we will need to use the canonical module $\omega_A$.

One way to define $\omega_A$ is via noether normalization. When $A$ is of finite type over a field $k$, then there is a polynomial ring $C$ over $k$ contained in $A$ such that $A$ is finite as a $C$-module. Then duality for a finite morphism implies that $\omega_A = \textnormal{Hom}_C(A, \omega_C).$ A polynomial ring has localizations that are regular local rings. Thus $\omega_C$ is isomorphic to $C$


great fun and will appeal enormously to those who consider themselves "Achievers," the unabashed, most loyal fans of "Lebowski." But others -- especially the supremely dated "Making of 'The Big Lebowski'," which was filmed in 1998 and looks it -- are just weak. Sadly, the picture quality of the movie, which has not been remastered for this edition, also appears somewhat grainy on larger, high-definition televisions. Clearly Universal Home Entertainment put some care into designing that bowling ball. Why not put the same effort into delivering a really sharp print of the film and a robust roundup of deleted scenes, commentary tracks and a longer, fresher behind-the-scenes documentary? Perhaps Universal thought the devoted-but-not-necessarily-mammoth fan base wouldn't generate enough profit to justify a jumbo-sized buffet of bonus features. Orsomething that is close to what is needed but the console isn't letting me save due to the Receiving__r in the FROM part of my query.
Any help or suggestions are greatly appreciated.
    trigger markRecRptPaid on Sesaco_Contract__c (after update) {
 Set<ID> maids = new Set<ID>();
    Sesaco_Contract__c ma = [Select Id, Amount_Paid__c From Sesaco_Contract__c Where Crop_Year__c = 'system.Date.year.today()'];
    for(Sesaco_Contract__c sc : Trigger.new){
        // Access old record
        Sesaco_Contract__c oldMA = Trigger.oldMap.get(SC.Id);

        if(oldMA.Amount_Paid__c != sc.Amount_Paid__c){
            maids.add(sc.Id);
        }


models to reproduce; and third, \[O$\,$III\]/H$\alpha$ in the edge-on spiral NGC 891 is found to [*rise*]{} with $z$ (Rand 1998), whereas it is expected to fall as oxygen becomes predominantly singly ionized.

Two explanations for this behavior have been put forth. While viable, both are limited by our knowledge of the energizing sources of halos in general. First, Reynolds, Haffner, & Tufte (1999) and Haffner et al. (1999) have pointed out for the Reynolds layer that the behavior of \[S$\,$II\]/H$\alpha$, \[N$\,$II\]/H$\alpha$ and \[S$\,$II\]/\[N$\,$II\] could be explained if gas temperature rather than dilution of the ionizing radiation field (and accompanying changes in the ionization state of the metals) were the key parameter that changed with $z$, since the first two ratios are very temperature sensitive while the third is not.a linear fit to the continuum on each side of the line. For uncertainties on intensities and central wavelengths, the variance of these quantities along each slit for sky lines of a range of intensities were determined, and an estimate of the dependence of these variances on sky line intensity was formed. This relation was then used to determine uncertainties for the emission lines of interest. The detection limit for intensities is about 10$^{-18}$ erg cm$^{-2}$ s$^{-1}$ arcsec$^{-2}$.

Results
=======

One of the most important results is the tremendous height above the plane to which emission can be detected, providing unique information on the ionization state and kinematics of gas at large distances above the midplane. \[N$\,$II\] $\lambda 6583$ is detected to about $z=13$ kpc and $z=7$ kpc on both sides


\[N$\,$II\]/H$\alpha$ reaching $>$1 in places. In general, these ratios rise more slowly with $z$ than in NGC 891. The relatively low and constant values on the NE side of Slit 1 arise from the bright filament, and may simply reflect the well established correlation between these ratios and H$\alpha$ surface brightness (Wang, Heckman, & Lehnert 1998; Rand 1998). In common with the East side of the halo in the spectra of NGC 891 (Rand 1997, 1998), \[N$\,$II\]/H$\alpha$ on the NE side of Slit 1 reaches a maximum at $z=6$ and subsequently falls, although the maximum is reached at only $z=2$ kpc in NGC 891. There is a suggestion of similar behavior in both lines on the SW side of Slit 1. \[S$\,$II\]/\[N$\,$II\] is reasonably constant in the haloto only $z=2$ kpc, where a value of \[O$\,$III\]/H$\beta=0.8$ was reached. Assuming optically thin gas at 10,000 K, the peak \[O$\,$III\]/H$\alpha$ of 1.2 corresponds to \[O$\,$III\]/H$\beta=3.7$.

\[O$\,$I\]/H$\alpha$ rises from around 0.02 in the disk to 0.06 at $z=2$ kpc on the SW side of Slit 2. He$\,$I $\lambda 5876$ has been detected in Slit 2, but only for four ten-pixel averages in the disk can meaningful values be measured. The mean of the four He$\,$I/H$\alpha$ ratios is $0.039 \pm 0.003$ (the uncertainty is the dispersion of the four values). There is no significant correlation of the ratio with H$\alpha$ intensity.

These data allow halo kinematics to be probed to unprecedented heights. Figure 3 shows velocity centroids of the \[N$\,$II\] $\lambda
6583$ and \[S$\,$II\] $\lambda\lambda 6716, 6731$ lines as a function of


for NGC 891 (Rand 1997), but here becoming roughly consistent with [*no*]{} rotation at the largest heights. The exact translation from observed to rotational velocities is complicated by the unknown distribution of gas along the line-of-sight. This issue will be explored in Paper III. Given the symmetry on either side of the two slits, it is unlikely that the kinematics are dominated by the tidal interaction NGC 5775 is undergoing. For Slit 1, the steeper falloff on the NE side may reflect a receding motion of the prominent filament. In Paper III, we will attempt to constrain the dependence of $v_{rot}$ with $z$ and examine whether the falloff is expected for a reasonable mass model, or whether other hydrodynamical effects (Benjamin 2000) may be important.

Discussion
==========

Without carrying out detailedthe extent to which gas can be expelled from the disk are relevant issues not only to the nature of the disk-halo cycle, but in the interpretation of QSO absorption line systems. For instance, Mg$\,$II absorption is probably due to both halos and disks (Charlton & Churchill 1998); consequently possible low-$z$ analogs of absorbers need to be well characterized at faint levels.

The help of the KPNO staff is greatly appreciated. We are also grateful to L. M. Haffner, R. Benjamin, and R. Reynolds for reading a draft of the manuscript.

Benjamin, R. A., 2000, in Astrophysical Plasmas: Theory, Codes & Models, eds. J. Arthur and J. Franco, Rev. Mex. A. & A., in press.

Charlton, J. C., & Churchill, C. W. 1998, , 499, 181

Collins, J. A., Rand, R. J.,


I chose to study at Oxford because the Department
of International Development is renowned
for its commitment to the field, particularly
in terms of research but also many of its
staff are involved in the policy debates around
a lot of development issues.
Development Studies is a relatively new discipline
where we try to understand the post-Colonial
trajectories of broadly the continents of
Asia, Africa and Latin America, but unlike
the more traditional disciplines we endeavour
to look at these continents and these spaces
through a multi- and interdisciplinary lens.
In your first year you'll be required to do
a foundation course in economics, history
and politics of developing areas and anthropology.
So my colleagues are political scientists,
anthropologists, economists and all of us,
what brings us together is our interest in
what is known as the developing world.
So fieldwork is probably the most exciting
part of theQ:

How to prevent someone from sending forms to my registration page? Is there even a point having capcha?

so the way users register right now is:
index.php:
user fills in registration form -> enters capcha -> get redirected after form validation.
process.php:
all inputted data is processed (htmlentities, tagstrip, mysql escapes etc..) and it gets added to database.
So the question is: if user knows form variables, and where it's being posted = the capcha wont stop bots, they can simply create a file with assigned variables on their server and send thousands of requests to my process.php file and it will all get inserted.
So what's even the point of capcha if it doesn't stop really anyone?
So anyways - How can I prevent such scenario from happening?

A:

You can use your server to generate a


A retrospective analysis of postrehabilitation outcomes following total knee arthroplasty.
Total knee arthroplasty (TKA) is one of the most frequently performed orthopaedic procedures in Canada. Despite the frequency at which TKAs are performed, few studies have examined the association between postoperative outcomes and long-term functional outcomes following group-based rehabilitation in Canada. The primary objective of the present study was to examine changes in flexion and extension from intake to discharge from rehabilitation in patients in Saskatchewan, Canada. A secondary objective was to explore the demographic and medical predictors of range of motion in TKA patients, and treatment duration. A retrospective chart review from an outpatient rehabilitation clinical database was conducted between September 2014 and December 2016, and assessed demographic and medical variables. A total of 672 patient charts werefunc(requestFile *os.File, err error) {
		if err != nil {
			capturedErr = err
			return
		}

		writer := multipart.NewWriter(requestFile)
		part, err := writer.CreateFormFile(fieldName, fileName)

		if err != nil {
			_ = writer.Close()
			capturedErr = err
			return
		}

		_, err = io.Copy(part, body)
		if err != nil {
			capturedErr = fmt.Errorf("%s: %s", T("Error creating upload"), err.Error())
			return
		}

		err = writer.Close()
		if err != nil {
			capturedErr = err
			return
		}

		var request *net.Request
		request, err = repo.gateway.NewRequestForFile("PUT", url, repo.config.AccessToken(), requestFile)
		if err != nil {
			capturedErr = err
			return
		}

		contentType := fmt.Sprintf("multipart/form-data; boundary=%s", writer.Boundary())
		request.HTTPReq.Header.Set("Content-Type", contentType)

		_, err = repo.gateway.PerformRequest(request)
		if err != nil {
			capturedErr = err
		}
	})

	return capturedErr
}


Business columnist and recreational social theoretician Gene Marks recently posted an article article on Forbes' website titled, "Why Most Women Will Never Become CEO," which is sort of like writing an article titled, "Why Most People Named Gene Will Never Become CEO." What Marks means, and what he writes about in the body of his article, is that most CEOs won't be women, which is true even in the wake of Ginni Rometty and Meg Whitman's recent promotions — according to USA Today, of the 3,409 publicly traded companies analyzed in a recent survey, only 98 of them were lead by female chief executive officers. For anybody who's nodding and muttering, "Well 98 seems pretty m'ok," that's just 3.2 %.

If you can ignore the article's incorrect title —rates of the two species indicates that despite the observed delays in a few genes in either *Pl* or *Sp*, the developmental progression is quite uniform throughout the embryonic territories and developmental window we study.

![Linear relationship between gene initiation times in *Sp* and *Pl*.\
Gene initiation times for each species was calculated using the sigmoid fit. Black line is the result of a linear regression of the *Sp-Pl* slope (slope of ×1.3, R^2^ = 0.84, interception was set to zero). The genes *six1/2* and *VEGF* were excluded from the linear regression as their temporal expression profiles indicate changes in their regulation.](pgen.1005435.g004){#pgen.1005435.g004}

### Temporal scaling and level normalization of *Pl* and *Sp* expression profiles reveals strong interspecies conservation of relative dynamics {#sec012}

The measured expression profiles in both species are highly dynamic


circuits or due to the structure of regulatory circuits that buffers genetic and environmental changes? We tend to support the second option and the ability of the regulatory system to overcome expression noise. This could be achieved by noise filtration mechanisms, *e*.*g*., the threshold activation suggested above, or by the use of network motifs that define different levels of sensitivity to upstream variation. For example, computational studies show that positive feedback circuitry is more efficient than other architectures in buffering noise in the inducing signal while keeping high responsivity to the level of the signal \[[@pgen.1005435.ref064],[@pgen.1005435.ref065]\]. On the other hand, incoherent feedforward motifs can generate consistent response to activating input that depends mostly on fold changes in input and not on noisy absolute protein levels \[[@pgen.1005435.ref064],[@pgen.1005435.ref066]--[@pgen.1005435.ref068]\]. Apparently, thisAnti-Brexit campaigners have brought traffic to a crawl on the main road between Northern Ireland and the Republic of Ireland.

A convoy of protesters staged a noisy motorway go-slow near Dundalk, Co Louth, on Saturday, using lorries and tractors to highlight the impact of predicted customs checks on the local economy.

As fears grow of a hard Brexit, the Irish government has begun contingency work to identify possible locations for checkpoints along the border with Northern Ireland.

The border in the island of Ireland has long been recognised as one of most problematic Brexit issues, with the potential to revive the tensions of the past.

During the Troubles there were only 20 crossings, but there are now thought to be as many as 250 after the peace settlement brought the reopening of


huge numbers of roads.

Since the end of the conflict traffic has passed largely unimpeded between the neighbours on what would be the UK’s only land border with Europe.

To highlight fears that a hard Brexit may stop such easy border crossings, a trailer-load of sheep going to market and passport-toting residents took part in a theatrical “checkpoint” staged to highlight the detrimental impact if new customs barriers were imposed.

A rusty Second World War-era bicycle placed alongside a mock customs hut reinforced the message that a hard border was a return to the past which Prime Minister Theresa May has been adamant she wants to avoid.

Traffic was brought to a near-standstill by the protest (Niall Carson/PA Wire ) (Niall Carson/PA Wire)

Local residents on the frontier between north and south saidthey were caught in the eye of a storm which could have a devastating impact on cross-border relations.

Kitchen maker and demonstration organiser for Border Communities Against Brexit, Declan Fearon, said: “We are really in the eye of the storm of Brexit and we intend to make sure that this does not happen.

“We never want to see this community going back to what it was before.”

Mock border officers from the UK and Ireland wearing traditional greatcoats waved down traffic in front of a stage customs hut.

Horns blared, truck drivers in the queue pretended to pull their hair out and waved pieces of paper supposed to be travel documents.

Lines of people with placards had gathered.

Vintage signs proclaimed “Stop: Customs”.

(Niall Carson/PA Wire ) (pictures by Niall Carson/PA)

Mr Fearon added: “The people


Construction of a controllable β-carotene biosynthetic pathway by decentralized assembly strategy in Saccharomyces cerevisiae.
Saccharomyces cerevisiae is an important platform organism for the synthesis of a great number of natural products. However, the assembly of controllable and genetically stable heterogeneous biosynthetic pathways in S. cerevisiae still remains a significant challenge. Here, we present a strategy for reconstructing controllable multi-gene pathways by employing the GAL regulatory system. A set of marker recyclable integrative plasmids (pMRI) was designed for decentralized assembly of pathways. As proof-of-principle, a controllable β-carotene biosynthesis pathway (∼16 kb) was reconstructed and optimized by repeatedly using GAL10-GAL1 bidirectional promoters with high efficiency (80-100%). By controling the switch time of the pathway, production of 11 mg/g DCW of total carotenoids (72.57 mg/L) and 7.41 mg/g DCW of β-carotene wasnipple so that the air will bubble upwardly through the liquid in the semi-inverted container. Alternatively, some infant bottles place the liquid in a flexible inner pouch which can contract in volume as the fluid is removed, so that no air need be introduced into the pouch as the fluid is removed. In either case the goal is the same; to provide means by which feeding can occur while the nipple is kept continuously full of fluid.
Thus it will be appreciated that, inasmuch as an air gap would always be presented at the open mouth of a container such as that taught in U.S. Pat. No. 388,677, such a container is not applicable for use in a bottle feeding context.
Still other fluid level indicators for containers are shown


would be long remembered.

"There has been one common refrain: that shiver of excitement when Australia's fast bowlers get going.

"Misty-eyed veterans talk of Lillee and Thomson, or Lindwall and Miller.

"Since the original whitewash, in 1920-21, the summer of Jack Gregory and Ted McDonald, the dangerous thrill of very fast bowling has been the animating spirit of Australian cricket."

HARD ROAD

The triumph moved Australia up to third from fifth in the test rankings and captain Clarke said he thought they had the talent to fulfil his long-stated ambition of returning to the summit, even it would be a hard road.

That road starts at the end of the month when they head to South Africa to take on the current world number one team in a three test series.

"There is no easyThere are numerous diverse forms of ninja blenders. Most of them are what is actually regarded as a kitchen area method exactly where they have bundled the regular blender with a foodstuff processor. nnThe Ninja Learn Prep is an incredibly perfectly-favored product with most at household cooks. This blender can choose the put of 2 house appliances on the kitchen area counter. It will complete the operate of the two your blender as nicely as your foodstuff processor. It will pulverize ice into a delectable smoothie or consume or it will dice foods to make delectable soups as properly as stews. nnThe massive 48 ounce pitcher arrives with an effortless pour spout. The base is created of material making it non-slip. It will make numerous drinks at at


the time.The food stuff processor component of the blender will dice, chop, puree, blend as properly as mince. nnIt has a four hundred watt motor to acquire care of just about any endeavor you will have. Both of those the processor with each other with the processing bowl has obtained 4 distinct ninja blades. Also integrated are storage tops. And elements are dishwasher resistant, anything all people requirements in this period. In addition to creating smoothies, you can even make milkshakes, margaritas, and even frozen goodies in the blender. In the foods processor component you can also make salsa and dips and great soups! nnAnother possibility is the Learn Prep Pro Method that features a heavier motor, a 9 velocity hand blender, and added containers. It has uniquely            Honorable Dick Alcala, Judge Presiding

       BEFORE JUSTICE ALVAREZ, JUSTICE CHAPA, AND JUSTICE PULLIAM

     In accordance with this court’s opinion of this date, the trial court’s judgment is
AFFIRMED. Costs are assessed against the party who incurred them.

      SIGNED June 17, 2015.

                                             _____________________________


Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging.
Serotonin-gated ionotropic 5-HT3 receptors are the major pharmacological targets for antiemetic compounds. Furthermore, they have become a focus for the treatment of irritable bowel syndrome (IBS) and there is some evidence that pharmacological modulation of 5-HT3 receptors might alleviate symptoms of other neurological disorders. Highly selective, high-affinity antagonists, such as granisetron (Kytril) and palonosetron (Aloxi), belong to a family of drugs (the "setrons") that are well established for clinical use. To enable us to better understand the actions of these drugs in vivo, we report the synthesis of 8-fluoropalonosetron (15) that has a binding affinity (Ki = 0.26 ± 0.05 nM) similar to the parent drug (Ki = 0.21 ± 0.03 nM). We radiolabeledaccess to clean water, and some 312,050 urban residents will enjoy improved sanitation.

“With this, achievements under the original project will be further consolidated and sustained, and more people in Binh Duong, in southern Vietnam, will enjoy better wastewater and drainage services,” said Achim Fock, the World Bank’s Acting Country Director for Vietnam.


the din and the shouting and the petty annoyances drive you mad? But of course you put up with it all because it’s an unforgettable spectacle.”

What we all want from travel is essentially the same, a vivid and memorable experience. So when I’m lined up on the sands of the Jersey Shore this weekend, and I see the first megayacht gliding across the horizon toward St. Barts, I will smile and ask myself: how much fun can that really be?

But I’ll try not to get too self-satisfied. We travelers should all remember that, even with increasingly affordable air travel, tourism is very much a first-world pursuit, and only a small percentage of the world’s population travels for pleasure in any capacity. (Statistics are few, but the United Nations’{
				curr_cos += ECORE_E3B0_PORT1_COS_OFFSET;
				new_cos += ECORE_E3B0_PORT1_COS_OFFSET;
			}
		}

		/* change queue mapping for each VNIC */
		for (vnic = 0; vnic < num_vnics; vnic++) {
			uint32_t pf_q_num =
				ECORE_PF_Q_NUM(q_num, SC_PORT(sc), vnic);
			uint32_t q_bit_map = 1 << (pf_q_num & 0x1f);

			/* overwrite queue->VOQ mapping */
			REG_WR(sc, ECORE_Q_VOQ_REG_ADDR(pf_q_num), new_cos);

			/* clear queue bit from current COS bit map */
			reg_addr = ECORE_VOQ_Q_REG_ADDR(curr_cos, pf_q_num);
			reg_bit_map = REG_RD(sc, reg_addr);
			REG_WR(sc, reg_addr, reg_bit_map & (~q_bit_map));

			/* set queue bit in new COS bit map */
			reg_addr = ECORE_VOQ_Q_REG_ADDR(new_cos, pf_q_num);
			reg_bit_map = REG_RD(sc, reg_addr);
			REG_WR(sc, reg_addr, reg_bit_map | q_bit_map);

			/* set/clear queue bit in command-queue bit map
			(E2/E3A0 only, valid COS values are 0/1) */
			if (!(INIT_MODE_FLAGS(sc) & MODE_E3_B0)) {
				reg_addr = ECORE_Q_CMDQ_REG_ADDR(pf_q_num);
				reg_bit_map = REG_RD(sc, reg_addr);
				q_bit_map = 1 << (2 * (pf_q_num & 0xf));
				reg_bit_map = new_cos ?
					      (reg_bit_map | q_bit_map) :
					      (reg_bit_map & (~q_bit_map));
				REG_WR(sc, reg_addr, reg_bit_map);
			}
		}
	}
}

/*


ECORE_PORT2_MODE_NUM_VNICS; vnic++)
		vnicWeightSum += input_data->vnic_min_rate[vnic];

	/* global vnic counter */
	if (vnicWeightSum > 0) {
		/* fairness per-vnic variables */
		for (vnic = 0; vnic < ECORE_PORT2_MODE_NUM_VNICS; vnic++) {
			/*
			 *  this is the credit for each period of the fairness
			 *  algorithm - number of bytes in T_FAIR (this vnic
			 *  share of the port rate)
			 */
			vdata->vnic_min_rate[vnic].vn_credit_delta =
				((uint32_t)(input_data->vnic_min_rate[vnic]) * 100 *
				(T_FAIR_COEF / (8 * 100 * vnicWeightSum)));
			if (vdata->vnic_min_rate[vnic].vn_credit_delta <
			    pdata->fair_vars.fair_threshold +
			    MIN_ABOVE_THRESH) {
				vdata->vnic_min_rate[vnic].vn_credit_delta =
					pdata->fair_vars.fair_threshold +
					MIN_ABOVE_THRESH;
			}
		}
	}
}

static inline void ecore_init_fw_wrr(const struct cmng_init_input *input_data,
				     uint32_t r_param __rte_unused,
				     struct cmng_init *ram_data)
{
	uint32_t vnic, cos;
	uint32_t cosWeightSum = 0;
	struct cmng_vnic *vdata = &ram_data->vnic;
	struct cmng_struct_per_port *pdata = &ram_data->port;

	for (cos = 0; cos < MAX_COS_NUMBER; cos++)
		cosWeightSum += input_data->cos_min_rate[cos];

	if (cosWeightSum > 0) {

		for (vnic = 0;Clear the parity error status registers.
 */
static inline void ecore_clear_blocks_parity(struct bnx2x_softc *sc)
{
	unsigned int i;
	uint32_t reg_val, mcp_aeu_bits =
		AEU_INPUTS_ATTN_BITS_MCP_LATCHED_ROM_PARITY |
		AEU_INPUTS_ATTN_BITS_MCP_LATCHED_SCPAD_PARITY |
		AEU_INPUTS_ATTN_BITS_MCP_LATCHED_UMP_RX_PARITY |
		AEU_INPUTS_ATTN_BITS_MCP_LATCHED_UMP_TX_PARITY;

	/* Clear SEM_FAST parities */
	REG_WR(sc, XSEM_REG_FAST_MEMORY + SEM_FAST_REG_PARITY_RST, 0x1);
	REG_WR(sc, TSEM_REG_FAST_MEMORY + SEM_FAST_REG_PARITY_RST, 0x1);
	REG_WR(sc, USEM_REG_FAST_MEMORY + SEM_FAST_REG_PARITY_RST, 0x1);
	REG_WR(sc, CSEM_REG_FAST_MEMORY + SEM_FAST_REG_PARITY_RST, 0x1);

	for (i = 0; i < ARRAY_SIZE(ecore_blocks_parity_data); i++) {
		uint32_t reg_mask = ecore_parity_reg_mask(sc, i);

		if (reg_mask) {
			reg_val = REG_RD(sc, ecore_blocks_parity_data[i].
					 sts_clr_addr);
			if (reg_val & reg_mask)
				ECORE_MSG(sc, "Parity errors in %s: 0x%x",
					   ecore_blocks_parity_data[i].name,
					   reg_val & reg_mask);
		}
	}

	/* Check if there were parity attentions in MCP */
	reg_val = REG_RD(sc, MISC_REG_AEU_AFTER_INVERT_4_MCP);
	if (reg_val & mcp_aeu_bits)
		ECORE_MSG(sc, "Parity error in MCP: 0x%x",
			   reg_val & mcp_aeu_bits);

	/* Clear parity attentions in MCP:
	 * [7]  clears Latched rom_parity
	 * [8]  clears Latched ump_rx_parity
	 * [9]  clears Latched ump_tx_parity
	 * [10] clears Latched scpad_parity (both


dati visibili in CSV',
          exporterSelectedAsCsv: 'Esporta i dati selezionati in CSV',
          exporterAllAsPdf: 'Esporta tutti i dati in PDF',
          exporterVisibleAsPdf: 'Esporta i dati visibili in PDF',
          exporterSelectedAsPdf: 'Esporta i dati selezionati in PDF',
          exporterAllAsExcel: 'Esporta tutti i dati in excel',
          exporterVisibleAsExcel: 'Esporta i dati visibili in excel',
          exporterSelectedAsExcel: 'Esporta i dati selezionati in excel',
          clearAllFilters: 'Pulire tutti },
        pagination: {
          aria: {
            pageToFirst: 'Prima',
            pageBack: 'Indietro',
            pageSelected: 'Pagina selezionata',
            pageForward: 'Avanti',
            pageToLast: 'Ultima'
          },
          sizes: 'elementi per pagina',
          totalItems: 'elementi',


Q:

Solving for DH Parameters

Given three sets of joint angles in which the end effector is in the same position, is it possible to find the DH parameters?
If the robot has 2 DOF in shoulder, 2 DOF in elbow, and 1 dof in wrist, with DH parameters as upper arm length, elbow offset in 1 axis, lower arm length, can this be solved, if so how?
I tried iterating through DH parameters to minimize position of end effector with forward kinematics, but this doesnt seem to work as DH parameters of 0 for everything makes 0 minimal distance.
Reason for this; given a physical robot, no DH parameters are known, and measuring by hand is not accurate.

A:

For a 5-DOF manipulator you will have 15 DH parameters. Three sets of joint anglescannot control shipping mishaps, unfortunately neither can you. If you receive an obviously damaged item due to shipping it will be your responsibility
to contact the shipping company and file the necessary claim(s) for a
potential reimbursement or replacement case. In the case of damaged
items/products claim we will be glad to provide any shipping/purchase
paper work to you at no additional cost via U.S Mail. As
of 12/16 we cannot and will not promise delivery by Christmas. Do not
purchase an item assuming it will be to you by Christmas because chances
are after 12/16 it will not.


to EE induced an anxiety-like effect in mice.

![Experiment 2.\
(A) Ethanol consumption for 2 h/day during 15 days of acquisition phase. (B-D) Elevated plus maze test: (B) percent time on open arms, (C) number of open arm entries, and (D) total number of arm entries. (E) Ethanol intake during 2 h access to two-bottle choice once per week. Ethanol intake calculations followed the same criteria as described for the first experiment. (F) Ethanol intake (g/kg) during 24 h of access to two-bottle choice on weeks 3 and 4. (G) Water intake during 2 h access to two-bottle choice. Water intake calculations followed the same criteria as described for the first experiment. (H) Water intake (ml) during 24h. Gray bars represent the measures of intake after exposure to the restraintis a normal part of aging, but, some health experts argue that it should not be. There’s a saying, “Men do not stop playing because they grow old, but they’ve grown old because they stopped playing.” Put more simply, if you stop living an active life chances are your muscles will also stop growing. So, part of the reason why people lose muscle mass is that physical activity also tends to decrease as age increases. But, many experts argue that muscle loss in aging can be prevented through exercise.

When Muscle Loss Accompanies Aging

Muscle loss is also medically referred to as sarcopenia. This refers to the process of losing muscle mass in the elderly and in people diagnosed with certain chronic diseases. After the age of 30, people start


The River Blog

Protect Our Rivers

header blog

Good news on the Kinnickinnic

It was recently announced by the EPA that dredging of toxic sediments is complete and the Kinnickinnic River is now on the path to restoration. This is great news and a great success!

American Rivers listed the Kinnickinnic River as one of our 2007 Most Endangered Rivers. The Kinnickinnic was threatened by toxic sediments with the presence of more than 170,000 cubic yards of toxic sediments laced with PCBs and polycyclic aromatic hydrocarbons (PAHs).

Fortunately, thanks to the Great Lakes Legacy Act and matching funds from the state of Wisconsin, dredging of toxic sediments started in June 2009 and is now complete.

I encourage everyone in the Milwaukee area to plan a visit to the river; to help celebrate all the greatvery least, a couple of times each week. For this post though, we’re talking only about your budget categories.

Family Budget: How Often Should You Update Your Budget?

Budgets are easy to forget about honestly. We get busy with life, stress happens, we add new expenses and we end old ones but we often forget to update those things in our budget. I call that budget blindness. Basically budget blindness happens when we’re “blind” to new expenses (aka we forgot to add something to our budget) or when we continue to budget for an expense that we no longer need or have.

The reason that is an issue should be obvious. No matter which one you forgot to do, it will cost you money and sometimes that cost can be quite


to become a six figure family and I would love if you came along with me! We'll kick off our shoes, sip sweet tea, eat loads of goodies, save some money and maybe even learn a thing or two along the way!OCI sticker from expired US passport to new US passport.
NOTE: Several relatives who tried taking their expired US passport with OCI sticker along with new US passport without sticker had difficulty entering India, even though they have OCI lifetime membership (again, India is entirely different system, hence I am posting here)

A:

To make this an actual answer:
It is no longer necessary to have any OCI sticker, and immigration officials will not require it. Instead, you can present your OCI card (booklet) in its place, in addition to your passport for your other nationality.
The official web site does say this, but in much less clear language. You may also read a contemporary news report which explains the new procedure: It is necessary only to present your passport and OCI card


Charlie Hebdo Paris Shooting: Canadian politicians react

As Canada awoke to news of the mass shooting targeting Parisian satirical magazine Charlie Hebdo that has reportedly left as many as 12 dead and 10 injured, politicians from across the partisan spectrum took to Twitter to express their shock and sadness at the events. Kady O'Malley has more.

Social Sharing

Prime Minister Stephen Harper 'horrified' by 'barbaric attacks'/*
 *     Generated by class-dump 3.3.4 (64 bit).
 *
 *     class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2011 by Steve Nygard.
 */

#import "NSComboBox.h"

@interface PBXExtendedComboBox : NSComboBox
{
}

- (BOOL)becomeFirstResponder;

@end


in order to find the characteristics.

Main results
============

Consider the difference equation (\[un2\]). Imposing the symmetry condition (\[LSC\]) we get $$\label{a1}
 Q(n+2,{u_{n+2}})-\frac{a  {u_n}^{2} }{{\left(b {u_n} {u_{n+1}} + 1\right)}^{2}}Q\left(n+1,{u_{n+1}}\right) + {\frac{a }{{\left(b {u_n} {u_{n+1}} + 1\right)}^{2}} } Q\left({n, u_n}\right).$$ The latter is an equation containing a function, $Q$, with different arguments making it difficult to solve. To overcome this, we shall assume that $u_{n+1}$ is a function of $n$, $u_n$ and $\omega$. We then proceed by differentiating (\[a1\]) with respect to $u_n$ (keeping $\omega$ fixed). This leads to $$\begin{aligned}
\label{a2}
\begin{split}
-Q'\left(n+1,{u_{n+1}}\right)+ Q'\left(n,{u_{n}}\right) - \frac{2}{u_n}Q\left(n,{u_{n}}\right)=0.
\end{split}\end{aligned}$$ By differentiating (\[a2\]) with respect to $u_{n}$ (keeping $u_{n+1}$ fixed) we obtain $$\begin{aligned}
\label{a5}
\begin{split}
 Q''\left(n,{u_{n}}\right) - \frac{2}{u_n}Q'\left(n,{u_{n}}\right) + \frac{2 }{{u_n}^{2}}Q\left(n,{u_{n}}\right)=0
\end{split}\end{aligned}$$ whose solution is given by $$\begin{aligned}
\label{a6}
\begin{split}
Q\left(n,{u_{n}}\right) = \alpha (n) {u_n}^2 +\beta (n) {u_n}
\end{split}\end{aligned}$$ for some functions $\alpha$ and $\beta$experience. For example, annual salaries ranged from $25-30,000 for 2-5 years of experience to $50-60,000 for > 20 years of experience. Median annual salaries were substantially higher for pharmaceutical and chemical/pesticide/petroleum companies ($50-60,000) compared to contract research laboratories ($35-40,000). Salaries for consultants were highly variable, ranging from under $15,000 per year to > $100,000 per year.


the Soviet-led occupation of Czechoslovakia in 1968, and the Soviet invasion of Afghanistan in 1979.

David’s sister, Maria Vulpe, told RFE/RL’s Moldovan Service that David’s time in the hospital had a devastating impact on her brother.

“They destroyed him with their drugs, with beatings, with God knows what he had to endure [in the hospital],” she said.

Ghimpu -- whose Liberal Party was in the pro-Western coalition government that collapsed last month -- indicated that he was outraged by the revelations about Timofti.

"The president sent a young man to a madhouse because that man spoke the truth!" Ghimpu said. "That man was not sick when he spoke the truth. The president should resign.”

Appeal For Forgiveness

Timofti was elected president in March 2012, ending a period of political deadlock in parliament that hadonly to the topology, we present a condition that considers also the values proposed by correct nodes. To understand the interest of our approach, let us consider the following example. One correct node $p_{i}$ proposes an initial value $v_{a}$ while all the other correct nodes propose an initial value $v_{b}$. In this particular scenario, if the node $p_{i}$ can receive values from a sufficient number of correct neighbors, approximate consensus can be reached even if all the other nodes are isolated and receive no message. This example suggests that the location of values is just as important as the network topology. In [@ex7; @ex15], constraints on the topology ensure that each node has enough neighbors. These constraints are “universal” because they affect all nodes in the network. In a


sequentially the [*reducing*]{} procedure (line 13) and the [*average*]{} procedure (line 14). Reducing operation has been introduced in [@ex1]. To ensure the validity property, a few values have to be removed from the multi-set $Neb_{i}(r)$. The strategy used in this paper leads to suppress between $f$ and $2f$ values while the strategy used in [@ex1] leads to always ignore exactly $2f$ values. To choose the removed values, $p_{i}$ compare the received ones with its own current value $v_{i}$. Within the set of values $Neb_{i}(r)$, $B$ is defined as the subset that contains the $f$ largest values (line 28) while $S$ is defined as the subset that contains all the $f$ smallest values (line 29). Due to the fact that the test of line 12 is satisfied, either at least $f$proposed condition.

The *convergence* property is satisfied by the proposed protocol if the following sufficient condition always holds:\
$\forall r \in S^{c}$ such that $v_{max}(r) - v_{min}(r) \geq \epsilon$,\
$\exists p_{i} \in C_n$ such that $p_{i} \in CMax(r) \cup CMin(r)$,\
$\exists r'$ such that $r \leq r'< r+R_{c}$,\
$\exists V_{q} \in V$ such that $V_{q} \subseteq JN_{i}^{r'}$,\
$\mid V_{q} \mid \geq f+1$ and $\forall p_{j}\in V_{q}$, $v_{j}(r')$ is a proper value.

As long as the convergence test is not satisfied, for each phase (characterized by its associated common new starting round $r$), at least one correct node $p_{i}$ among those which are members of the groups $CMin(r)$ or $CMax(r)$ must, at least once during the phase ([*i.e.*]{} during a round $r'$), compute a new value using $f+1$ (quantity constraint) proper values (quality constraint) received during


previous formula, we conclude that:\
$d-d' > v_{min}(r') + \frac{\delta}{n} - v_{min}(r')$

We have proved the existence of a particular positive value of $\Delta$ (during round $r'$) that is small enough to imply that the value of $\Delta$ can be negative during the next round. If during round $r'$, the value of $\Delta$ (which is equal to $d - \mu$) is strictly less than $\frac{\delta}{n}$, then the value of $\Delta$ can be negative during round $r'+1$. This contradict the fact that $\mu$ is a limit for $v_{max}-v_{min}$ which is never violated.

At this stage, we have just demonstrated that $\mu$ is not a limit. We now show that after some time, this limit will be breached permanently. To understand why a violation of the limit $\mu$ is sometimes transient, let uswho is actively resisting verbal commands is a threat to officer safety," sniveled the union. "When a suspect fails to comply with verbal commands, it means the situation is rapidly escalating and some form of force will be required to gain compliance. Non-lethal force is the safest and best way to obtain the needed compliance. Non-lethal force instruments are designed to avoid injury to both officers and suspects by swiftly incapacitating the suspect."

Two problems thrust themselves upon us. The first is posed by the fact that the Taser is not a "non-lethal" weapon; it is a frequently lethal one.

The second problem is best stated as a question: What about those increasingly common incidents in which innocent individuals are faced with unwarranted and improper police demands for "compliance"? Why


striatum at days 3--56. The numbers were 60 ± 8 at day 3 (*n* = 5), 54 ± 12 at day 7 (*n* = 7), 70 ± 15 at day 28 (*n* = 6), 68 ± 4 at day 56 (*n* = 7) in dorsolateral striatum and 67 ± 15, 59 ± 16, 69 ± 8, and 66 ± 10 in central striatum while the numbers of normal neurons in sham rats (*n* = 4) were 104 ± 13 in dorsolateral striatum and 94 ± 5 in central striatum. The ischemia reduced the number of normal neurons in striatum (see [Figure 1](#fig1){ref-type="fig"}, mean ± S.D., ANOVA, *p* ≤ .01). Moderate-to-severe "spongy" changes (defined as empty spaces in histological sections) in striatum were present at day 56 in 5total number of NeuN-positive neurons in the dorsal portion of the SN, including SNC and SNL, was 212 ± 42 versus 270 ± 42 (ischemic rats, *n* = 6 versus sham rats, *n* = 3; *p* \> .05) at day 56.

Many eosinophilic and shrunken neurons (indicating apoptosis) were seen in midbrain including substantia nigra (SN) at day 56 (Figures [2(a)](#fig2){ref-type="fig"}--[2(c)](#fig2){ref-type="fig"}). Six of 7 ischemic rats displayed apoptotic neurons in SN. Some apoptotic neurons were noticed in the perivascular regions ([Figure 2(c)](#fig2){ref-type="fig"}). The numbers of apoptotic neurons in the SN at day 56 are 20 ± 13 (ischemia, *n* = 7) versus 4 ± 3 (sham, *n* = 4, *p* \< .05, ANOVA). In the midbrain beyond the SN, 81 ± 70 versus 16 ± 10 were detected (*p*


5) were also tested.

After training, the preischemia traversing beam score was 6 for all 30 rats. The traversing score of sham rats reached 6 point (no faults) at 48 hours after surgery while ischemic rats did not reach 6 until day 56. Compared to sham rats, the ischemia rats had significantly lower scores at days 1, 2, and 7 after the insult (see [Figure 9(a)](#fig9){ref-type="fig"}). At day 56, the score of ischemia group reached 6; however, the ischemic rats traversed slower than sham rats, and the mean time for traverse was 11.8 ± 5.4 (ischemia, *n* = 7) versus 5.6 ± 1.2 seconds (sham, *n* = 5) ([Figure 9(b)](#fig9){ref-type="fig"}). Compared to preischemia the rats walked significantly slower at day 56: the traverse time was 4.88 ± 0.92 versus30%--40% of normal-neurons loss in dorsal striatum produced by ischemia, impaired motor control may be a direct consequence of the degeneration of GABA systems in the SN. Behavioral impairment could be related to the damage of the other brain regions critical for motor (primary motor cortex). However, there was no paralysis in the experimental rats; thus, the pyramidal system function seemed intact. The animals slowness on beam traverse implies that postischemic animals might be hampered by the disturbance of coordination, that is, bradykinesia, due to significant GABA system degeneration in the SN and neuronal loss in striatum after transient global ischemia. It should be noted that Huntington\'s disease (HD) is associated with excitotoxic neurodegeneration of medium spiny neurons (MSNs) in the striatum. These neurons are also acutely vulnerable


ischemia in rats (H&E staining). Eosinophilic and shrunken neurons (arrows) are present in SN ((a)--(c)). (b) is a magnified view of the boxed area in (a). Eosinophilic and shrunken neurons are adjacent to injured blood vessels (c). Striata show severe or moderate spongy changes ((d), (e)) which are proximate to abnormal perivascular area (e). The active astrocytes were detected by anti-GFAP in SN of sham rat (f) and in ischemia rat at day 56 (g). No astrogliosis was observed in both groups.](CPN2010-506952.002){#fig2}

![Illustration of GAD67, VGAT, and CR immunostaining in substantia nigra (SN) and the surrounding regions in sham rat on coronal midbrain sections. Immunoreactivity (ir) of GAD and VGAT is high in substantia nigra par reticulata (SNR). The strong CR-ir displays in pars compacta (SNC) and lateralis (SNL)... the FIRST GENERATION MONTE CARLO CLUB! Dues paying FGMCC members who participate in this event for more than 100 miles will each receive a $25 gas card. In addition, the FGMCC will sponsor food for everyone at one stop in IL, up to $100.

If you have suggestions of a company(s) or group(s) that might consider such a contribution to this event, please advise me.

**** THE PEOPLE ****

This is for ALL ages and levels of interest in Route 66. The FOCUS is OLDER cars, but newer cars are welcome, too! If you'd like to participate and want to ride with someone, please advise. We'll see what we can do to assist in making such arrangements.

I'm posting this to various groups/clubs:

ValveReplacement

ACHAheart.org

IL Monte Carlo Owners Group

MI MC Group

NY MC Club

MC


we drive....

... I've started contacting Route 66 businesses and Associations to discuss possibilities/details and have received wonderful responses. I look forward to further replies and information. "Highlights" and websites related to these conversations include:

...and a tour of the California Route 66 Museum (Victorville), right before the ending dinner (which will push the dinner back to about 5:30p or 6p, instead of starting at the current itinerary time of 4:30p)....

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Changes to the CURRENT ITINERARY (posted in early March) are taking place.

In the NEXT UPDATE (a month or so from now), I will post a REVISED ITINERARY which will incorporate the links and list of places to visit I have noted in the last update and below in this update. I also hopeto have a few more details ironed out/in process.

In the meantime, more notes....

1 ... Even if you are just THINKING about joining us for any part of this, PLEASE ADVISE ME...NOW! I am hoping to secure more sponsors and, perhaps, some blocks of rooms and restaurant reservations along the way.

2 ... I've continued to contact Route 66 businesses and associations to discuss possibilities/details and have received welcoming replies thus far. I look forward to more feedback and plans being made as I continue to make contacts in the next month or so....

3 ... To continue the list of visits to places, etc., that I started in the last update, "highlights" for additional contacts I've made thus far since that last update include:

4 ... I still have many plans


you a map of Chicago.No matter how hard you tried or how positive you remained, trying to find my house would still end in frustration.Effort and attitude are really important, but only if you have the correct map.Does connecting with your teen or your spouse feel this way sometimes?Are you making the effort and trying to stay hopeful, but still getting the wrong outcome? Maybe it is time to challenge the accuracy of the map.

Each of us has many maps in our heads, which can be divided into two main categories:Maps that are Real and maps that are Imagined.But our brains can’t tell the difference between Real & Imagined – So we fill in the gap and believe all of it is real.We interpret everything we experience throughBuilding One’s House With Straw, which has been translated into several languages. Jean-Baptiste is also the co-founder of the Approche Paille association, which has trained some 1,000 people in the GREB technique… thanks to this work, today there are almost 400 such houses in France and others in Belgium, Italy, Spain, Rumania, Ukraine, but also in Chile, Argentina and even in Morocco!

But why is this technique not more developed when it appears to be so efficient? Patrick gives his opinion on that: “The current house is a mirror of our society: it has to confer a certain social status to the owner, just like the car. In this consumption world, a straw house does not quite fit in with the trend of the day…” In the collective subconscious


technique through Quebec, and to build bridges between the territories to push legislations forward everywhere!” says Pierre.

Ecovillage on winter

Heating

For the inhabitants of the eco-village, the ecological house means much more than just the walls. Each house must meet certain characteristics which have been registered with the town-hall in the local town planning scheme. Especially as regards the south façade with large bay windows to enable the heat and the sun rays to enter. As for heating, the inhabitants chose masonry heaters, which, together with the GREB mortar, add significant thermal inertia. This choice does enable the house to store the heat emitted and spread it uniformly for several hours. Another advantage of such heaters is the complete combustion of the wood, i.e. the gases are also burnt insteadof being rejected in the environment as is the case with the traditional open fires.

To get even further benefits from the energy produced, pipes run through the masonry heaters to heat the water of the house in winter. When spring comes around, solar panels take over. Patrick’s idea was to fit photovoltaic panels (converting light into electricity) rather than thermal panels (converting heat into electricity): “This is a completely heretic idea in the scientific community and it is certainly true that in the hot countries, thermal panels are more efficient to heat the water. But in Quebec, because of the cold and freezing temperatures, they are far less efficient. Working on simulations, I noticed that using photovoltaic panels in our latitudes would be 3 and 5 times cheaper


than thermal sensors. Together with the lower cost of photovoltaic panels, the idea to connect such panels directly onto the boiler brought the return on investment down from 75 years to 20. That is true for the south of Quebec which enjoys very cheap electricity thanks to hydroelectricity. But if we consider the northern parts where they get their electricity from oil power stations, we are on investment returns between 3 and 4 years!”

Towards resilience

Beyond the houses, the inhabitants of the eco-village and all the people working on it are actually focusing on another project. Benoît Thévenard, Jean-Baptiste’s brother, also understood something when he went through the GREB. “At the beginning of my career as an engineer in aeronautics, I did not quite understand what was at stakeSymantec products, Symantec Security Response, and secure@symantec.com are registered trademarks of Symantec Corp. and/or affiliated companies in the United States and other countries. All other registered and unregistered trademarks represented in this document are the sole property of their respective companies/owners.


ongoing trend with my dressmaking, but I suspect sooner than later I will start understanding what my true size is.

If it wasn't for the alterations, this would have taken no more than a few hours from start to finish. It is simple and uncomplicated and for any new sewers out there, give it a go!! I am definitely going to make another one, in fact it would seem a shame not to!

So whilst I was packing and tidying, I spotted a pattern for a sunglasses case (again part of this month's Love Sewing Magazine) and needless to say I just somehow had to make one...

Fortunately it was really quick sew that I just about managed to squeeze in and I must say I'm very impressed with yet anotherhave a super busy week planned, I will do what I know works best, good food, yoga and a little down time. I am still incredibly strict with my routine and diet and I am feeling all the much better for it. There is one word the keeps coming back to me over and over, if you are DISCIPLINED, you can achieve so much in life!

Leaving you with this sweet little sign, that pretty much sums up how I feel!

Sunday, 3 August 2014

Helloooo. Well its a good thing I've got this monthly mandalong thingy going on as otherwise I would never get to blogland. Honestly I don't know where the time goes or what I do with it (well I do to some extend), but I never seem


# Be sure to restart your server when you modify this file

# Specifies gem version of Rails to use when vendor/rails is not present
RAILS_GEM_VERSION = '2.3.18' unless defined? RAILS_GEM_VERSION

# Bootstrap the Rails environment, frameworks, and default configuration
require File.join(File.dirname(__FILE__), 'boot')

# Hot patch since Gem.source_index was deprecated in later rubygems
unless Gem.method_defined?(:source_index)
  module Gem
    def self.source_index
      sources
    end

    def self.cache
      sources
    end

    SourceIndex = Specification

    class SourceList
      # If you want vendor gems, this is where to start writing code.
      def search( *args ); []; end
( c ( cons 4 a ) ) ) ... )

Here you have two lists (4 3 2 1) which share a common tail. If both lists are live at the moment of GC, we don't want to copy this tail twice, because that would result in it being split into two distinct objects. Then, a set-car! on a might only be reflected in b but not c , for example. The forwarding pointers prevent this from happening by simply adjusting a copied object's constituent objects to point to their new locations. Finally, after all data has been copied, all the newly copied objects are checked again for references to objects which may have been relocated after the object was copied.

The precise algorithm that performs this operation is


to find so many references to it, which all lead to a a paywall on the ACM website.

I think it's absurd that the ACM charges $15 for a paper which is over forty years old, and only two measly pages long. What sane person would plunk down 15 bucks to read 2 pages, especially if it is possibly outdated, or not even the information they're looking for?

The ACM's motto is "Advancing Computing as a Science & Profession", but I don't see how putting essential papers behind a paywall is advancing the profession, especially considering how many innovations now happen as unpaid efforts in the open source/free software corner of the world. Putting such papers behind a paywall robs the industry from a sorely-needed historical perspective, and it stiflesby default. You can enable the build of your MVC views in Visual Studio like that:

Right click on your project in Visual Studio
Unload project
Edit project
Change the value for MvcBuildViews from false to true<?xml version="1.0" encoding="utf-8"?>
<Project ToolsVersion="4.0" DefaultTargets="Build" xmlns="http://schemas.microsoft.com/developer/msbuild/2003">
...
<MvcBuildViews>true</MvcBuildViews>
...
Reload project

Next time you compile and there are errors in your MVC views, it will not compile.
The downside is, the compilation process will take longer.
Update
Here is an answer on SO, explaining how to avoid the error:

It is an error to use a section registered as allowDefinition='MachineToApplication' beyond application level. This error can be caused by a virtual directory not being configured as an application in IIS