but allowed him to make up a party of the
most experienced fishermen he could select. A lot of harpoons and
tridents were lowered into a boat, into which got Bichri and two
archers, carrying some lines to be attached to the harpoons to haul
up the fish that were hit. Jonah, ever on the alert when food was
in question, asked permission to join the party, and was allowed
to go under condition that he brought his trumpet and some torches
to attract the fish. It had been ascertained that Aminocles was a
skilful hand at this pursuit; and as soon as he was satisfied that
there was no fear of his encountering any of the monsters of which he
had heard so much, he was induced to accompany them.

"How was it," he said to Himilco, "thatI do not think he will let him go in a
hurry."

When we had finished our repast, some slaves appeared with torches to
attend us to our ships. We did not quit the palace the same way as
we had entered, but after descending the staircase to the next lower
floor of the tower, we passed through a door into the sloping gallery
of what is called a "curtain;" into this the quarters of the soldiers
opened, the chambers themselves being built in the thickness of the
outer wall; we then passed into a vaulted hall, whence a corridor
brought us to the gate of the palace adjacent to the Admiralty-basin.
A private barque was waiting to convey us to our ships, where we
found the sailors, who by my orders had not been allowed to leave
their posts,


basin of what serves equally for trade-harbour and
war-port, our trumpets were sounded, and we saluted the town with
three ringing cheers.

We had reached our goal, and were in Tarshish at last.

CHAPTER XIII.

THE SILVER MINES OF TARSHISH.

The town of Gades, though not large, is neat and trimly built, and
in the well-kept gardens in the environs, pomegranates, oranges, and
lemons, which have all been introduced by the Phœnicians, flourish
in great abundance. About the centre of the town, and in direct
communication with the harbour, is the market, the emporium not only
for the wedges of silver brought from the mines in the interior, but
for barrels of the salted murenæ that are caught on the neighbouring
shore; for Tarshish cats,[38] to be used in rabbit-hunting; for
iron, which is obtained in small quantities from the north; andthey demand most exorbitant wages for their
labour."

"Peaceable you call them, do you?" broke in Himilco; and pointing
to the empty socket of his eye, said, "Yes; perhaps if using their
lances to scoop out people's eyes is a proof of peaceableness, the
Iberians of Tarshish are supremely peaceable; but I confess I don't
quite see it."

Ziba smiled. Although she was a thorough woman of business, she had a
keen appreciation of a joke.

"Yes, pilot," she replied; "I very well recollect your misfortune
when you were here before; indeed, it was I myself who dressed your
wounds with oil and rosemary. But you may take my word for it that
the tribes on the Bœtis are far more anxious to take your goods
than to do you any bodily injury. In time, I have no doubt, they will
become


legs a bit!" he said, as he
saw the men loaded with their burdens.

"Now then, get on, you brutes!" Himilco screamed in Iberian; "and the
first rogue that shirks his work is a dead man!"

Placing the prisoners in the middle, we proceeded cautiously to
continue our ascent; and while we were prosecuting our toilsome
march, I asked Bichri to give me full particulars about the encounter
with Bodmilcar.

"As accurately as I can," he said, "I will. On leaving you we
advanced without obstruction some hundred paces into the wood, when
in a moment we found ourselves with a host of Iberians in our front,
and as many in our rear, pelting us with stones and darts. We ran
full speed to a spot where the trees were not so thick, and planting
our backs against a projecting rock,a trumpeter before he will give his daughter in marriage
to this chief. I am spared as well. We are to be sent off at once to
the northern chief. Keep up your spirits. We will soon escape. Beware
of Bodmilcar; he is laying an ambush. He means to cut you off from
the river.' There, my men, that's what he says. We will hope to see
him yet."

As I ceased to read, Chryseis threw herself into Abigail's arms,
and wept for joy; Gisgo flung his cap into the air; Himilco took
a liberal draught from his goat-skin; and Hannibal manifested his
emotion by sneezing seven times in succession. As for Bichri, he took
the monkey in his arms, and fairly hugged it, a piece of attention
which Gebal acknowledged by plucking out a handful of his hair.

"O,


dozing at the foot of the mast, when I was aroused by
Himilco's stentorian shout, "Breakers ahead!"

In an instant I was upon my feet, and at the helmsman's side.

"Backwater!" I shouted, "and signal the other ships."

All hastened to light the torches and lamps; but it was too late--a
long cry of distress made us aware that the _Dagon_ had already
stranded, and as I tacked about to effect a retreat, I witnessed the
heart-breaking spectacle of the _Cabiros_ completely heeled over, and
lying in the very midst of the breakers.

The _Ashtoreth_, although she was hitherto uninjured, was environed
by reefs which were level with the surface of the water. The current
was so strong that all my efforts to get back to the channel by
which we had entered were unavailing, and after an hour's struggle
Ishall either have to buy ourselves off by a ransom or invent some
ruse to escape."

The sailor who was with us, speaking now for the first time,
reminded us that there were several canoes moored to the causeway,
and Himilco recollected having noticed them. This set us speculating
whether we could devise any means of getting at the canoes, and using
them to facilitate our escape. Hannibal declared that we should still
be in the clutches of the savages, even if we got to land; but Bichri
and Chamai maintained that once free they could take good care of
themselves.

I interrupted them to inquire whether any one amongst them had a
knife, but it proved, as might have been expected, that the savages
had not left us anything of the sort.

"Then roll yourself over here, Bichri," I said,


as large as the
Egyptian Nile; its banks were covered with thick woods; numbers of
crocodiles and hippopotamuses were visible in the water by its shore;
and great birds, uttering shrill and piercing cries, whirled around
above our heads.

For four days we wandered about without finding any sign of human
being; we obtained, however, an abundance of wild fruit, and shot
several buffaloes and antelopes, of which a great portion of the
flesh was carried on board and salted. On returning from one of the
foraging excursions, Bichri came running to me, looking utterly
woe-begone; he was followed by Dionysos, weeping bitterly, and Jonah,
gesticulating vehemently, and apparently as much agitated as himself.

"What's the matter, Bichri?" I asked.

"Gebal has gone!" he exclaimed; "he has been carried off by
Bodmilcar's monkeys."

I burst out laughing. In his indignation he looked asfigs, raisins, and a double allowance of
wine were served out to the men; and we ourselves took our seats upon
brilliant carpets that had replaced the worn-out rags with which we
had been so long familiar, and for the first time for months, nay,
years, enjoyed the viands of Tyre and Sidon, and quaffed the wines of
Byblos and Arvad.

Our spirits rose to the occasion, and I should hesitate to say how
many times I filled and refilled my wine-cup before I began to
recount the adventures which Ethbaal was anxious to hear.

My story lasted far on into the night.

When I had finished, Ethbaal, who had never flagged for one moment in
his attention, raised his hands to the stars in the heavens above,
and swore by all the gods that my chronicle ought to be


by, that
the volley of missiles intended for our deck went splashing and
crashing down upon the water in our wake; and as we retraced our
course on the other side just as rapidly, I called out to Bodmilcar
that I meant to serve his ship as I had served the Egyptian galley at
Tanis. Himilco, too, did not spare him some cutting jokes upon his
dilemma.

Having returned to my own ship, I ordered the _Adonibal_ and the
_Cabiros_ to make a joint attack with me upon one of the two galleys,
and then to get right ahead of the other. We made the assault with
the very utmost of our strength; the galley made a desperate effort
to escape us, but it was too late; before she could move I had stove
in one of her sides, and  discovered in the foundation of Carthage, probably originated
    in the national symbol affixed to the Phœnician ships.

    The true Sidonian war-ship is the fifty-oared galley:

    ναῦν πεντηκόντορον Σιδόνιαν.
      EURIP. _Hel._ 1141.

    What was the tonnage of such a vessel, or how it could be
    worked by only fifty oars, or carry 400 men, are matters on
    which I give no opinion; it is not my province to enter upon
    any technical arguments.

    If an analogy be required, it may be suggested by the huge
    Chinese junks which were seen by the Arabian, Ibn Batuta,


ago.

For centuries, we had no idea what the far side of the moon looked like. But starting in 1959 — when the USSR's Luna 3 probe first photographed it — we learned that it has very few maria and tons of craters.

Scientists still aren't totally certain why this is the case. Some first proposed that Earth shields the close side of the moon, limiting the number of asteroid impacts. But if you were standing on the near side of the moon, scientists have calculated, Earth would only block out about 4 square degrees (out of 41,000 square degrees that make up the whole sky), which isn't nearly enough to account for the discrepancy in craters.

Other theories hold that the moon's far side has a thinner crust, which hasmeant fewer volcanic eruptions over time. These would have produced fewer maria and also covered up fewer craters.

Still, the moon's south pole has a very thin crust, but few maria, challenging this theory. The truth is that for all the exploring we've done of the moon, we still don't know a ton about its far side and have never sent a rover or lander to its surface.

That may change in 2020, when China tentatively plans to send the first rover to the far side. Doing so could teach us a lot about the moon's geology — and shed light on one of its biggest mysteries.

VIDEO: Solar and lunar eclipses, explained


i gave him my card with email and phone numbers... never thinking he would call me. long story short, he called we had lunch, that was all. but we got along, he move from here to los angeles, we kept in touch on line,, we met again in LA and spent two wonderful days and nights together. he just left my house yesterday after spending a week with me. No details, but i am still recovering. so just take a chance... say hello, hi, your cute, want to meet for a coffee.. etc... jerry

Ask him to join you for a drink after he gets off work--the worst thing he can do is reject you and that would be his loss!

Deleted Member

Deleted Member

Posted December 16, 2013

Thomas, I know howused here)? [I suspect the answer is yes, since there's a lot of Wikipedia data on there under the same license.]
How well does Amazon support a public data set that has updates every few months? What's the procedure for providing an update? Does the new data set replace the old one, or are multiple snapshots kept?

I'm willing to put in the work to make the data set available on AWS every time a new one is released. I asked the SE team about this and the response was basically "Interesting idea, ask on meta", so I'm now soliciting input.
My own situation is that I create a few things every time the data dump is released:

Stack Exchange stats
Stack Overflow ebooks
Unofficial Stack Overflow deleted question archive

The data dump is getting


fairly large, and takes a while to download (to this remote Pacific island with bandwidth limits and monthly data caps). I also might soon need more compute horsepower than what I've got available with my own hardware, since it now takes a few days to run through all the processing. I'd like to use EC2 to do the actual data crunching. I could of course just transfer it myself, but making it widely available seems like a good idea.

A:

We have applied to be a part of the Public Data Sets at Amazon.  We'll keep you updated as we learn more about how this process works.

{
    TRTI2(args, NULL, range_n, sa, sb, 0);
    return 0;
  }

  lda	 = args -> lda;
  a	 = (FLOAT *) args -> a;
  args -> ldb = lda;
  args -> ldc = lda;
  args -> alpha = NULL;

  start_j = 0;
  while (start_j < n) start_j += NB;
  start_j -= NB;

  for (j = start_j ; j >=0 ; j-= NB)
  {
	jb = n - j;
	if ( jb > NB ) jb = NB;

	args -> n = jb;
	args -> m = n-j-jb;

	args -> a = &a[(j+jb+(j+jb)*lda) * COMPSIZE];
	args -> b = &a[(j+jb+j*lda) * COMPSIZE];
	args -> beta = beta_plus;

        TRMM(args, NULL, NULL, sa, sb, 0);

	args ->


Thirty-three Alamo Wing members participated in Exercise Swift Response 2019, a six-week long event across Europe, which concluded in June.

The Army-led exercise is a coalition, joint, total-force training event with service members and support from the United States, Canada, France, Germany, Hungary, Italy, Netherlands, Spain and the United Kingdom.

The team from Joint Base San Antonio-Lackland consisted of Reserve Citizen Airmen from the 433rd Contingency Response Flight, the 433rd Logistics Readiness Squadron, as well as the 26th and 74th Aerial Port Squadrons.layer deposited on a substrate and the other plate may comprise a metallic membrane separated from the stationary layer by an air gap. As described herein in more detail, the position of one plate in relation to another can change the optical interference of light incident on the interferometric modulator. Such devices have a wide range of applications, and it would be beneficial in the art to utilize and/or modify the characteristics of these types of devices so that their features can be exploited in improving existing products and creating new products that have not yet been developed.


decided that it should begin to allow and encourage free public reference access and to concentrate particularly on Irish studies, politics and culture, both because it was already strong in these areas and so as not to compete with the expanded Central Reference Library. The move was a success. The number of subscribers began to increase and the library increased its role as a cultural centre, both facilitating research and fostering close links with the wider community.

It quickly became apparent that lack of space was holding back the library's revival. After spending ten years exploring various options before purchasing a 999-year lease on the upper floors of some neighbouring property in 1996. This was followed by an extensive fundraising campaign to pay for the development of this newthat alcohol use is not a problem. • “Client is resistant to treatment.” • In the past 12 months, the client has dropped out of 3 treatment programs prior to completion. (other possibilities?) • “Client is on probation because he is a bad alcoholic.” • Client has legal consequences because of alcohol-related behavior.

Terms • What Components Are Found in a Treatment Plan? • Problems identified during assessment • Goals reasonably achievable in the active treatment phase • The term objectives used in this training is defined as what the client does to meet the goals • The term intervention used in this training is defined as what the staff will do to assist the client

Prioritizing Problems Writing a Specific Goal • Recovery is not a specific goal •


so-called “troika” of lenders—the European Commission, the European Central Bank and the International Monetary Fund—on new reforms that are slated to go into effect in 2019.

The SYRIZA-led Greek government touted this agreement as a major success that signifies the end of austerity. According to the Greek government, austerity will be averted via the enactment of “equivalent measures” that will offset cuts. But even if this is the case, the agreement is contingent on Greece fulfilling harsh fiscal targets and austerity measures from now until 2019.

What does this agreement really mean for Greece? Is it the best solution for the country and its economy? Are these targets even realistic? To provide insight into these and other relevant questions, MintPress News recently spoke with Greek economist Dimitris Karousos, a memberalmost 87 billion euros, which could be used as foreign currency reserves in the immediate aftermath of the departure from the Eurozone. Therefore, it is easy to understand that there is no chance of there being any shortages in the marketplace and that Greece’s needs would be met for several years to come.

MPN: There is also the Greek public debt to contend with. Is this debt sustainable to begin with? What would you propose regarding dealing with the debt, and what does international law and international legal precedent have to say regarding what actions Greece could take regarding its debt?

DKThe Greek people have been purposefully led to believe that an “unsustainable” debt is one which is very difficult to repay, but which can, at some point and after


it is likely that countries whose national debt is in large part denominated in U.S. dollars, as is the case with Turkey, where 65 percent of its debt as a percentage of GDP is in dollars, as well as developing countries whose major public- and privately-owned industries have outstanding loans in U.S. dollars, will face increased difficulties from upward pressure on the dollar in international financial markets.

In addition to all of this, we need to take into consideration the ongoing trade battle between the United States and China and the efforts of the United States to achieve energy autonomy, especially the elimination of dependence on OPEC nations. This means the replacement of approximately three million barrels of oil per day that are currently imported. They’ll have to beLearn about older dog health issues & ways to help

It is important to be aware of older dog health issues, with good care and if your dog does not suffer any major illness or accident, they should live happily into middle to old age.

How long your dog lives also depends on the breed. Large and medium sized breeds live to about 11 to 14 years, small breeds like the Dachshund can live to 15 years or older.

My friend’s
dachshund has just turned 16 yrs and is very much full of life, but
mostly in short bursts with a sleep in between.

Signs of aging

General slowing down

Sleeping more and deeper sleep

Loss of interest in family activities

Less enthusiasm for long walks.

Some older dog health issues to be aware of :

Controlling weight

This issue is


issue as muscles become less
efficient. Many older dogs have a problem with little accidents which upsets both owner and dog.

A natural remedy to assist this problem is Better-Bladder Control Formula. This homeopathic formula has worked wonders for many dogs in this situation. The remedy helps restore bladder control and improves muscle strength in bladder and urethra.

Anal Glands

One of the main problems with anal glands (scent glands) is they don't empty fully and over time this builds up, which gives the dog discomfort.To learn more about this issue, visit our dachshund health problems page.

Behavioral changes

These changes can be similar to Alzheimer’s in people some
dogs develop a canine version, showing loss of interest and becoming
confused in familiar situations.

Some older dogs may show some aggression when teased or annoyed, which
is outin mRNA levels in GC-treated, treated and challenged chicken versus PBS-injected and non-challenged animals (panels A and D), PBS-injected and *C. jejuni* challenged chicken (panel B), or GC-treated and non-challenged chicken (panels C and E). Significant differences in ΔmRNA values were analyzed using log transformed data as described in Materials and Methods. Significant differences are indicated: \*\**P* \< 0.005; \**P* \< 0.05.

To more specifically determine the strong dampening effect of the GC treatment on the *C. jejuni*-induced tissue response, we compared gene transcript levels in the GC-treated, *C. jejuni* challenged animals (group 3) with those in the non-GC treated, *C. jejun*i-challenged chickens (group 4). This demonstrated that GC treatment reduced the *C. jejuni*-induced *IL-8* and *IL-6* response by \>150-fold at Day 1 post-challenge ([Fig. 4B](#f0004){ref-type="fig"}). On Day 4, the


cecal colonization (3.10^9^ CFU at Day-2 after challenge) simply results in a more rapid bacterial dissemination. Another is that GC treatment causes a general increased translocation of bacteria across the intestinal barrier. We considered these explanations as less likely as GC treatment has been reported to support rather than weaken intestinal barrier function.[@cit0034] We favored the scenario that the GC-induced dampening of the local innate immune response facilitates the bacterial spread to distant organs.

Analysis of the expression of inflammatory genes in the cecal tissue after challenge with *C. jejuni* revealed a strong increase *IL-6, IL-8* and *iNOS* transcripts. This pro-inflammatory signature in the non-GC treated animals indicates that *C. jejuni* is sensed by the chicken immune system and elicits a potent local immune response as previously noted.[@cit0007] The81116 (NTCT 11828)[@cit0047] was grown on Blood agar base II medium (Oxoid) containing 5% horse blood lysed with 0.5% saponin at 42°C under microaerophilic (5% O~2~, 10% CO~2~, 85% N~2~) conditions. S*almonella enterica* serovar Enteritidis (*S.* Enteritidis, nalidixic acid resistant) strain CVI-1 was grown on Luria-Bertani (LB) plates (Biotrading) at 37°C. Bacteria from cloacal swabs and serial dilutions of tissue homogenates were grown on *Campylobacter* selective blood-free agar plates with CCDA-selective (Oxoid SR0155E) supplement (*C. jejuni*) or on Brilliant Green Agar supplemented with 100 µg/ml of nalidixic acid (*S.* Enteritidis) to suppress growth of resident flora. For use in challenge experiments, *C. jejuni* and S. Enteritidis were grown in Heart Infusion broth and Brain Heart Infusion broth (Biotrading) with nalidixic acid (Sigma-Aldrich) respectively, collected by centrifugation (4,000 × *g*,


10 min), and resuspended in PBS. Bacterial suspensions (10^5^ CFU in 0.25 ml) were administered orally to the chicken using a 1 ml syringe that was carefully placed deeply into the mouth (7 cm).

Cell culture {#s0004-0002}
------------

The chicken macrophage HD11^49^ and MQ-NCSU[@cit0050] cell lines were propagated in 25 cm^2^ tissue culture flasks (Corning) containing 5 ml of Dulbecco\'s modified Eagle medium (Life Technologies) supplemented with 5% fetal bovine serum (FBS) at 37°C and 10% CO~2~. For use in cell stimulation assays, cells were seeded onto 12- or 24-well plates (10^5^ cells/well) in 1 ml of DMEM plus 5% FBS per well.

Chicken experiments {#s0004-0003}
-------------------

Fertilized SPF (*Campylobacter* and *Salmonella* free) chicken eggs (Ross 308) were kept at 38°C and 65--75% relative humidity in a forced air chicken egg incubator. After hatch, the chickens were divided into 6 groupswere sacrificed by cervical dislocation by professional staff to be able to determine the number of *C. jejuni* or *S.* Enteritidis in the cecal contents and liver, and to collect tissues for transcript analysis (see below). For bacterial enumeration, serial dilutions of 1 g of cecal content or 1 g of liver tissue homogenized in 3 ml of peptone water, were grown as described above. The number of colonies (CFU) was counted after 24--48 h of incubation. Collected tissues were snap-frozen in liquid nitrogen and stored at −80°C until further analysis. All chicken were cared for in accordance with accepted procedures of the Dutch law of animal welfare and all animal experiments were approved by the Ethics Committee of the Central Veterinary Institute of Wageningen University, Lelystad, the Netherlands.

A gamma generalized linear


indicated amounts of purified LPS, flagellin, or bacteria. After the indicated incubation periods (37°C, 10% CO~2~), cell culture supernatants were collected for measurement of nitric oxide (NO). The cells were treated with RNA-Bee™ (Bio-connect) to extract RNA for transcript analysis (see below). Purified LPS and *Salmonella* flagellin (FliC) were isolated as previously described.[@cit0014]

RNA isolation from tissue and cells {#s0004-0005}
-----------------------------------

RNA was isolated from the collected tissues by placing approximately 50 mg of tissue in a LYSING matrix tube (MP Biomedical GmbH) containing 1 ml of RNA-BEE™ on ice. Cells were disrupted in MagNA lyser instrument (Roche) (6,500 × g, 50 sec, 20°C). Total RNA was extracted from the lysate using the RNA-Bee™ isolation kit according to the instruction of the manufacturer. Contaminating DNA was removed by treatment of the RNA sampleswith DNase (1 U/µg of RNA, Fermentas). The quantity and purity of the isolated RNA was verified using a NanoDrop ND-1000 spectrophotometer. For isolation of RNA from cultured cells, 10^5^ cells were collected in 250 µl of RNA-Bee™ and directly subjected to the RNA-Bee extraction method described above. Purified RNA was stored in 25 µl of RNase-free water and stored at -80°C until further analysis.

Quantitative real-time RT-PCR analysis {#s0004-0006}
--------------------------------------

Quantitative real-time PCR on isolated RNA was routinely performed using the Reverse Transcriptase RT-qPCR Master Mix kit (Eurogentec). The reaction was performed in a Roche LightCycler®480 using 50 ng of DNase I-treated RNA samples as template and the primer sets and probes listed in [Table 1](#t0001){ref-type="table"}. Probes for *IL-8 (CXCL8-CXCLi2), IL-6, IL-1*β and *IFN*β were labeled with the fluorescent reporter dye 5-carboxyfluorescein (FAM) at the


treatment. Table 1.Primers and probes used in this study.chGAPDHForwardGCCGTCCTCTCTGGCAAAGReverseTGTAAACCATGTAGTTCAGATCGATGAprobe(FAM)-AGTGGTGGCCATCAATGATCC-(TAMRA)chIL-8 (CXCL8)ForwardGCCCTCCTCCGGTTTCAGReverseCGCAGCTCATTCCCCATCTprobe(FAM)-TGCTCTGTCGCAAGGTAGGACGCTG(TAMRA)chIL-1ßForwardGCTCTACATGTCGTGTGTGATGAGReverseTGTCGATGTCCCGCATGAprobe(FAM)-CCACACTGCAGCTGGAGGAAGCC-(TAMRA)chIFNβForwardACAACTTCCTACAGCACAACAACTAReverseGCCTGGAGGCGGGACATGprobe(FAM)-TCCCAGGTACAAGCACTG-(TAMRA)chIL-6Forward5′- GCT CGC CGG CTT CGAReverse5′-GGT AGG TCT GAA AGG CGA ACA GProbe5′-AGG AGA AAT ACC TGA CGA AGC TCT CCA-(TAMRA)chiNOSForwardGGCAGCAGCGTCTCTATGACTTGReverseGACTTTAGGCTGCCCAGGTTGchG6PDHForwardCGGGAACCAAATGCACTTCGTReverseCGCTGCCGTAGAGGTATGGGA

Statistical analysis on all RT-qPCR results was performed on log transformed data the GraphPad Prism 6 multiple *t* test corrected for multiple comparison using the Holm-Šidák method, with α = 5.000%

Nitric oxide assay {#s0004-0007}
------------------

For measurement of nitric oxide (NO) production, the Griess assay was employed. In brief, cell supernatants collected after 17 h of incubation with the bacterial TLR agonist (or controls) were incubated (10 min, 20°C, in dark) with an equal volume (50 µl) of Griess reagent 1 (1% sulfanilamide, Sigma-Aldrich). Then, an equal volume of Griess reagent 2 (0.1% N-naphthyl ethylene diamine dihydrochloride (Sigma-Aldrich) in 2.5% phosphoric acid) was added.necessary asymptotic behaviour as $$\frac{m_i^2}{Q_i^2} = \frac{m_i}{m+M} + {\cal O}(\beta^{1/2})~, \qquad
\frac{\Delta_{ij}}{Q_i^2} = {\cal O}(\beta^2)~.$$ The first dual propagator $G_D(q_1;\ell)$ is free of threshold singularities and thus leads to a real expansion independently of the sign of $\beta$. The expressions obtained for both $r_{12}$ and $r_{21}$ can be used both when approaching the threshold from below and from above because the infinitesimal imaginary component accompanying $\beta$ is fixed by the complex prescription of the dual propagators. While in the case below threshold no singularity appears in the propagator on the real axis, it does exist in the complex plane and approaches the path of integration as can be seen in figure \[fig:polposition\].

In all the kinematical regions studied, we have achieved their asymptotic expansions by conveniently selecting the expansion parameters


momentum itself, that is for the hard region one performs the replacements $$\{\ell^2, M^2\} \to \lambda^2 ~\{\ell^2, M^2\}~, \qquad p\cdot\ell \to \lambda ~ p\cdot \ell~,$$ and expands for $\lambda\to\infty$. The assumed relationship between the large loop momentum and both its square and its scalar products does not account for cancellations between the energy component and the spatial components which will take place when integrating over the unrestricted components of the loop momentum. The Taylor series with the prescriptions above and comparable ones for the soft region leads to the expanded integrands $$\mathcal{A}^{(1)}_\text{hard} &= \int_\ell \left( \frac{1}{\ell^2} + \frac{m^2}{(\ell^2)^2}+ \frac{m^4}{(\ell^2)^3} + \dots \right) \left( \frac{1}{\ell^2-M^2} +\frac{2p\cdot \ell - p^2}{(\ell ^2-M^2)^2}+\frac{4(p\cdot \ell)^2 + p^2}{(\ell ^2-M^2)^3} + \dots\right)~, \nonumber\\
    \mathcal{A}^{(1)}_\text{soft} &= \int_\ell \frac{1}{\ell^2-m^2} \left( - \frac{1}{M^2} - \frac{(p-\ell)^2}{M^4}$n\geq~3$. The asymptotic expansions in and display the same logarithmic dependence, although they differ in the rational coefficients accompanying the logs, which partially encode higher orders in the expansion. This is due to the fact that $\Delta_{12}$ includes subleading terms. The expression in also contains a logarithmic dependence on $\ln{M^2/p^2}$, which is formally one order higher than and cancels when more terms in the dual expansion are included.

             $G_D$ expansion     $\mathcal{O}(M^{-2})$   $\mathcal{O}(M^{-4})$                                   EbR
  ------- ---------------------


and automatization. The behaviour portrayed here has been seen as well in a modification of the scalar-two point function which has been rendered -finite by increasing the power of one of the propagators, with the only relevant difference being that the same order of both the soft and the hard integrand-level expansion had to be combined.

Asymptotic expansion of the scalar three-point function {#sec:scalar3pt}
=======================================================

[triangle]{}

(200,200)

As a benchmark application with more external legs, we consider the scalar three-point function at one-loop as shown in figure \[fig:triangle\] with all the internal masses equal $${\cal A}_3^{(1)} = \int_\ell G_F(q_1,q_2,q_3; M)~,$$ where $G_F(q_1,q_2,q_3; M) = \prod_{i=1}^3 G_F(q_i, M)$, with $q_1=\ell+p_1$, $q_2 = \ell+p_1+p_2$ and $q_3=\ell$. Applying LTD to this integral leads to $${\cal A}_3^{(1)} = - \int_\ell \left[ \td{q_1} G_D (q_1; q_2, q_3) +1,832,809, issued to Hudson; 1,898,242, issued to Chandler; 3,248,080, issued to Plasko; 3,257,094, issued to Vischer Jr.; and 3,387,784, issued to Brenchley. It has also been proposed to provide such remotely actuatable motor valves with means for indicating the condition of the valve element, as can be seen in U.S. Pat Nos. 2,347,523, issued to Suksdorf; 2,451,989, issued to Smith; and 2,560,897, issued to Schmohl. However, it has not been proposed to interpose a motor valve between an embalming machine and an injection needle, a motor valve having an indicating apparatus providing an output indication of the position of the valve in conjunction with a valve control unit located proximate to a working area, such as the foot control units shown in U.S. Pat. Nos. 497,144, issued to


screen is white i dont see pics in camera pls tell whats the issue of camera pls solution ? ...
Fuji FinePix S5000 Digital Camera

White Screen I take some pictures and the camera works fine. But this morning when i switched the cam to take photos i see only a white screen with the aperture and speed numbers.
Read like have a bright light in front of the lens. I took some photos but just took a white screen. The LCD of the camera work fine but i see other photos that i take.
The day before this begin, i have take pictures without light, in the night.
Can anyone have solution or recomendation to this?
I have exact

Hi,Normally there are two reasons for the given problem.1). Bad or defective CCD. and/or2). shutterthe contacts are clean. If necessary try another memory card.\015\012 ...
Sanyo VPC-T1060 Digital Camera

LCD screen I am using my sisters camera over the next two weeks and cant figure out how to get the lcd screen to work while i am taking a photo. It is fine to review the photo and takes photos fine but i can see what i am taking the photo of unless i look through the eye piece. I cant get hold of her for the next two weeks and i dont have the manual can anyone help? Is there a button or setting i have to put it on?

Canon PowerShot A480 won't take photo. Pressing on button camera on then pressing silver button to take photo when pressed down screen turns black


unlicensed cosmetology, unlicensed practice of geology, discharge into a storm drain, spitting on the sidewalk, barratry, champerty, maintenance, affray, seduction, or being a common scold—at any point today? Under the Eleventh Circuit’s rule (which some other circuits also use), police or officials can arrest and silence a Deyshia Hargrave when a politician wants to silence her—if, after the fact, some earnest lawyer can find a such a law, however obscure, that police at the time might have thought she was violating, even though they weren’t thinking about that.char *) digest, MD5_DIGEST_LEN);
  Curl_MD5_update(ctxt, (const unsigned char *) ":", 1);
  Curl_MD5_update(ctxt, (const unsigned char *) nonce,
                  curlx_uztoui(strlen(nonce)));
  Curl_MD5_update(ctxt, (const unsigned char *) ":", 1);
  Curl_MD5_update(ctxt, (const unsigned char *) cnonce,
                  curlx_uztoui(strlen(cnonce)));
  Curl_MD5_final(ctxt, digest);

  /* Convert calculated 16 octet hex into 32 bytes string */
  for(i = 0; i < MD5_DIGEST_LEN; i++)
    snprintf(&HA1_hex[2 * i], 3, "%02x", digest[i]);

  /* Generate our SPN */
  spn = Curl_auth_build_spn(service, realm, NULL);
  if(!spn)
    return CURLE_OUT_OF_MEMORY;

  /* Calculate H(A2) */
  ctxt


   [in]     - The session handle.
 * userp   [in]     - The user name.
 * passdwp [in]     - The user's password.
 * request [in]     - The HTTP request.
 * uripath [in]     - The path of the HTTP uri.
 * digest  [in/out] - The digest data struct being used and modified.
 * outptr  [in/out] - The address where a pointer to newly allocated memory
 *                    holding the result will be stored upon completion.
 * outlen  [out]    - The length of thedigest->nc = 1;

  if(!digest->cnonce) {
    unsigned int rnd[4];
    result = Curl_rand(data, &rnd[0], 4);
    if(result)
      return result;
    snprintf(cnoncebuf, sizeof(cnoncebuf), "%08x%08x%08x%08x",
             rnd[0], rnd[1], rnd[2], rnd[3]);

    result = Curl_base64_encode(data, cnoncebuf, strlen(cnoncebuf),
                                &cnonce, &cnonce_sz);
    if(result)
      return result;

    digest->cnonce = cnonce;
  }

  /*
    If the algorithm is "MD5" or unspecified (which then defaults


(Perhaps Rails uses a NOW() function for created_at as opposed to passing in a DateTime).
Which leads to my ultimate question:
How can I get ActiveRecord to preserve millisecond resolution on timestamp fields?

A:

ActiveRecord should preserve the full precision from the database, you're just not looking at it properly. Use strftime and the %N format to see the fractional seconds. For example, psql says this:
=> select created_at from models where id = 1;
         created_at
----------------------------
 2012-02-07 07:36:20.949641
(1 row)

and ActiveRecord says this:
> Model.find(1).created_at.strftime('%Y-%m-%d %H:%M:%S.%N')
 => "2012-02-07 07:36:20.949641000"

So everything is there, you just need to know how to see it.
Also note that ActiveRecord will probably give you ActiveSupport::TimeWithZone objects rather than DateTime objects but DateTime preservesthe result of [@Slepian1973] only applies to discrete random variables whereas here $Y_M$ is continuous. The variable $Y_M$ can however be quantized into a discrete random variable $Y_q$ such that $H(X|Y_q)$ approaches $H(X|Y_M)$ with arbitrary precision, and the Slepian-Wolf Theorem still holds.

Practical reconciliation algorithms will introduce an overhead $\epsilon_{rec}>0$ and require the transmission of $M_{rec}=nH(X|Y_M)(1+\epsilon_{rec})$ additional bits. The reconciliation can also be characterized by its efficiency $\beta$ which is defined as

$$\beta(\epsilon_{rec}) = 1-\epsilon_{rec}\frac{H(X|Y_M)}{I(X;Y_M)} \leq 1.$$

At the end of the reconciliation step, Alice an Bob share with high probability the common sequence $X^n$ whose entropy is $n_{rec}=nH(X)$. We will assume that $X^n$ is then compressed into a $n_{rec}$-bits binary sequence $S$. For our application to the Gaussian wiretap channel we use multilevel coding (at Alice) and multistage (MS) decoding (at


general still difficult, however conditioned on the typicality of the bit sequence [@Maurer2000] $R(S|Y_W^n=y_W^n)$ and $H(S|Y_W^n=y_W^n)$ become equal. Hence if $n$ is large enough, $nH(X|Y_W)-nH(X|Y_M)(1+\epsilon_{rec})-2s-2$ is a good lower bound of $R(S|E=e)$, and choosing $$k = n\beta I(X;Y_M) - nI(X;Y_W)-2s-2-r_0,$$ guarantees that Eve’s uncertainty on the key is greater than $k-2^{-r_0}/\ln 2$ with probability $1-2^{-s}$. For our protocol in this paper we do not develop anything new, and we use standard families of hash functions [@Carter1979; @Wegman1981].

**4. Secure communication**. The secret key generated $K=G(S)$ can finally be used to secure Alice’s message, using either a one-time pad for perfect secrecy or a standard secret key encryption algorithm and Eve’s uncertainty $H(K|G,E=e)$ about the key is as close to $k$ as we want as per (\[eq:uncertainty\_bound\]).

LDPC Constructions for Gaussian Reconciliation {#sec:reconciliation}
==============================================

In this\rangle}_{\mathcal{D}}}$$ bits of message per symbol. From section \[sec:reconciliation\], we know that reconciliation requires the transmission of ${{\langle H(X|Y_M)+(1-\beta) I(X;Y_M) \rangle}_{\mathcal{D}}}\approx{{\langle H(X)-\beta C_M \rangle}_{\mathcal{D}}}$ additional bits per symbols on average. The minimum size of a universal familiy of hash functions $\mathcal{G}:{\left\{0,1\right\}}^{n_rec}\rightarrow{\left\{0,1\right\}}^{k}$ is at least $2^{n_{rec}-k}$ [@Stinson1991] and privacy amplication therefore requires the transmission of $n_{rec}-k$ bits. No hashing scheme is known to achieve this bound for any $n_{rec}$, therefore we will consider the more realistic situation where privacy amplification requires the transmission of $n_{rec}$ bits. For instance, this can be achieved with the following family [@Wegman1981]: $$\mathcal{H}_{\mbox{GF}(2^{n_{rec}})\rightarrow\{0,1\}^{n_{key}}} = \left\{h_c: c\in\mbox{GF}(2^{n_{rec}})\right\},$$ where $h_c(x)$ is defined as $n_{key}$ distinct bits of the product $cx$ in a polynomial representation of $\mbox{GF}(2^{n_{rec}})$. Finally, since the maximum number of non-secure bits transmitted is at most the


capacity of the main channel, we obtain: $$\label{eq:commthroughput}
\overline{\mathcal{T}_c}(\eta) = {{\langle C_M \rangle}_{\overline{\mathcal{D}}}} - {{\langle H(X)-\beta C_M \rangle}_{\mathcal{D}}} -  {{\langle H(X) \rangle}_{\mathcal{D}}}-\eta^{-1} {{\langle \beta C_M-C_W \rangle}_{\mathcal{D}}}.$$ Notice that $\overline{\mathcal{T}_c}(\eta)$ may be negative when ${{\cal P}}(C_s\geq C_s^t)\gg {{\cal P}}(C_s < C_t^s)$. This situation corresponds to a regime where Alice and Bob generate keys faster than they use them, which can be avoided by adjusting the parameter $C_t$ so that $\overline{\mathcal{T}_c}(\eta)$ remains positive. In the remaining of the paper, we will be interested in the ultimate performance of the protocol, therefore according to section \[sec:reconciliation\] we will assume $H(X)\approx C_M+2$ but unless otherwise specified we will use $C_M^t=0$ and $\beta=1$.

The maximum average secure throughput for $\eta=1$ achievable by the opportunistic protocol is shown Fig. \[fig:throughput\_vs\_capacity\].

![Average secure throughput (thin lines) and average secrecythis slight increase in $\alpha$ suffices to ensure the secrecy of the keys generated. The mitigation is less effective when $\sigma^2=10$, and a further increase of $\alpha$ would be necessary to reduce the leaked throughput.

Conclusions and Future Work
===========================

In the second of this two-part paper on wireless information-theoretic security, we proposed a protocol based on one-way communications providing secure communication over quasi-static wireless channels. This scheme opportunistically exploits the fluctuations of the fading coefficients to exchange information-theoretially secure keys, which are then be used to encrypt messages. We analysed the security provided by the protocol in the idealized case where the channel state information of the wiretap channel is known, but also showed that secure communication is still achievable in the more realistic situation where only imperfect channel state


their current level of security.

[10]{} \[1\][\#1]{} url@rmstyle \[2\][\#2]{}

M. Bloch, A. Thangaraj, S. W. McLaughlin, and J.-M. Merolla, “L[DPC]{}-based secret key agreement over the gaussian wiretap channel,” in *Proc. IEEE International Symposium on Information Theory*, Seattle, USA, 2006.

M. Bloch, J. Barros, M. R. D. Rodrigues, and S. W. McLaughlin, “An opportunistic physical-layer approach to secure wireless communications,” in *Proc. 44th Allerton conference on Communication Control and Computing*, Allerton, USA, September 2006.

——, “L[DPC]{}-based secure wireless communication with imperfect knowledge of the eavesdropper’s channel,” in *Proc. IEEE Information Theory Workshop*, Chengdu, China, October 2006.

J. Forney, G.D. and G. Ungerboeck, “Modulation and coding for linear gaussian channels,” *IEEE Transactions on Information Theory*, vol. 44, no. 6, pp. 2384–2415, Oct. 1998.

E. Biglieri, J. Proakis, and S. Shamai, “Fading channels: information-theoretic and communications aspects,” *IEEE Transactions on Information Theory*, vol. 44, no. 6, pp. 2619–2692, Oct. 1998.

A. D. Wyner, “The [W]{}ire-[T]{}ap [C]{}hannel,”/*
 * Copyright (c) 2015-2017 Meltytech, LLC
 * Author: Dan Dennedy <dan@dennedy.org>
 *
 * This program is free software: you can redistribute it and/or modify
 * it under the terms of the GNU General Public License as published by
 * the Free Software Foundation, either version 3 of the License, or
 * (at your option) any later version.
 *
 * This program is distributed in the hope that it will be useful,
 * but WITHOUT ANY WARRANTY; without even the implied warranty of
 * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
 * GNU General Public License for more details.
 *
 * You should have received a copy of the GNU General Public License
 * along with this program.  If not, see <http://www.gnu.org/licenses/>.
 */

#ifndef AVFOUNDATIONPRODUCERWIDGET_H
#define


remember to add stamping in there somewhere!

Show
us how unique you can be, create anything your imagination cares to dream up! Share your
cards, journal pages, layouts, 3D assemblage or whatever else takes your
fancy. Your project can be any colour you want... as long as
you've stamped somewhere, then you're good to go!

We
have two prizes on offer, as always. The first is the Sponsor Prize,
and the winner of this will be randomly chosen from all the eligible
entries of the challenge. To make sure your project is eligible to win,
make sure you have followed our challenge guidelines. These can be found on our sidebar over here ---------->

and also in a tab under the banner at the top.PLEASE REMEMBER: We only want to see ONE project in each individual blog post entry!A setbetween viewing a small reward immediately (smaller-sooner reward, or SS) or a large reward after a variable delay (larger-later reward, or LL). We varied the decision characteristics across four experimental task conditions (see [Figure 1](#fig1){ref-type="fig"}). In the Willpower task, participants were required to actively resist choosing the SS, which was available throughout the delay period as they waited for the LL. In the Choice task, participants made an initial choice between SS and LL; if they chose LL, they passively waited for the LL during a delay period in which the SS was not available. In the Precommitment task, participants decided whether to remove their ability to choose the SS, thus committing to the LL. In the Opt-Out task, participants decided whether to make a nonbinding choice to wait


for the LL; during the delay period, the SS was still available, so they could reverse their choice at any time. All tasks were economically equivalent in terms of rewards, delays, motor responses, and trial durations, and participants were informed of the duration of the delay at the time of choice. Because all trials were equally long, to maximize reward in this paradigm, participants should always choose LL. We examined self-control (here defined as the proportion of LL choices) across our experimental conditions in a behavioral study (Study 1) and an fMRI study (Study 2).

Results {#sec2}
=======

Behavioral Task Validation {#sec2.1}
--------------------------

As a manipulation check, we first tested whether self-control decreased as a function of delay. As expected, across all task conditions, participants were more likely to choose LL at shortt~(19)~ = 0.64, p = 0.5294; [Figure 4](#fig4){ref-type="fig"}B). Directly contrasting BOLD responses from Precommitment trials in which subjects chose to precommit, against BOLD responses from Willpower trials in which subjects actively resisted temptations, revealed a significant cluster in right LFPC (40, 56, −12; t~(19)~ = 4.78, p = 0.039, whole-brain FWE corrected) and a trend-level significant cluster in left LFPC (−26, 52, −12; t~(19)~ = 5.11, p = 0.059, whole-brain FWE corrected).

Next, we examined the LFPC's involvement in the three tasks involving explicit decisions (Precommitment, Choice, and Opt-Out). We extracted parameter estimates from our ROI in LFPC based on a previous study (−34, 56, −8; [@bib6]) for LL decisions in the three decision tasks and conducted a repeated-measures ANOVA to compare LFPC activation across tasks ([Figure 4](#fig4){ref-type="fig"}C). This analysis demonstrated a significant main effect of task


selection, remaining so for the duration of the delay. The LL reward was not available for selection until the end of the delay phase. Participants could terminate the delay phase at any time by selecting the SS, at which point they entered the reward delivery phase, followed by the ITI. In order to select the LL reward, participants had to resist the temptation to choose the available SS for the duration of the delay until the LL reward became available.

In the Choice task ([Figure 1](#fig1){ref-type="fig"}B), participants initially made a simple choice between LL and SS during the decision phase. If SS was chosen, participants entered the reward delivery phase, followed by the ITI. If LL was chosen, participants entered the delay phase, followed by the reward delivery phase andstandard six-channel SENSE head coil and a T2^∗^ sensitive gradient echo (EPI) sequence (96 × 96 matrix, repetition time \[TR\] 2,000 ms, echo time \[TE\] 30 ms, flip angle \[FA\] 80°, 34 slices, 2.3 mm × 2.3 mm voxel size, 3-mm-thick transverse slices). Stimuli were presented using Eprime 1.2 software (Psychology Tools). The behavioral responses were collected by an fMRI-compatible four-button response box (Lumitouch).

All image preprocessing and analysis was carried out in SPM8 (Wellcome Department of Imaging Neuroscience). Images were realigned to the first scan of the first session, spatially normalized via segmentation of the T1 structural image into gray matter, white matter, and CSF using ICBM tissue probability maps, and spatially smoothed with a Gaussian kernel (8 mm, full-width at half-maximum).

We regressed fMRI time series onto a general linear model (GLM) with separate


Task Conditions\
Participants completed all four conditions, presented in random order. Each task consisted of a decision phase (4,000 ms), a delay phase (0--10,000 ms), and a reward phase (2,500 ms). Participants chose between smaller-sooner (SS) and larger-later (LL) visual rewards. Delay length was indicated above the LL option. Solid lines indicate reward available for selection, while dashed lines indicate reward that is unavailable for selection. Choice options were initially blue and turned orange upon selection.\
(A) In the Willpower task, participants had to actively resist choosing the available SS reward during the delay phase.\
(B) In the Choice task, participants simply chose the SS or LL reward during the decision phase. If LL was chosen, the SS was unavailable during the delay phase.\
(C) In the Precommitment task, participants decided whether or not toQ:

.show() doesn't show!

paragraph 1

show

clicking on link doesn't trigger .show() at all!
What am i doing wrong??
Update: i tried $(document).ready({...  it doesn't help!

A:

A few things to keep in mind, load the scripts only after the document has finished loading:
$(function(){
  /* Scripts here will run only
     after the document has loaded */
});

Also, be sure to prevent the default behavior of links when using them to trigger actions:
$(function(){
  $("#sh").click(function(e){
    e.preventDefault();
    $("#container").show();
  });
});

With these changes, the code works as expected: http://jsfiddle.net/apsje/


---
title: "Command - devspace delete"
sidebar_label: devspace delete
---

the "loft" plugin

## Synopsis

```
devspace delete [flags]
```

```
the "loft" plugin
```

## Flags

```
  -h, --help   help for delete
```

## Global & Inherited Flags

```
      --config string         The devspace config file to use
      --debug                 Prints the stack trace if an error occurs
      --kube-context string   The kubernetes context to use
  -n, --namespace string      The kubernetes namespace to use
      --no-warn               If truewhose results were published last month in The Journal of Neuroscience. "Alcohol diminishes our ability to hold on to pieces of information like your colleague's name, or the definition of a word, or where you parked your car this morning. But our subconscious is learning and remembering too, and alcohol may actually increase our capacity to learn, or 'conditionability,' at that level."

Morikawa's study, which found that repeated ethanol exposure enhances synaptic plasticity in a key area in the brain, is further evidence toward an emerging consensus in the neuroscience community that drug and alcohol addiction is fundamentally a learning and memory disorder.

When we drink alcohol (or shoot up heroin, or snort cocaine, or take methamphetamines), our subconscious is learning to consume more. But it doesn't stop there. We


2009 7DRL competition), but instead, took me about 60 days to complete.

I have a bloggy type thing here, where I post random stuff, short fiction and other random stuff:

http://iamagiantnerd.com

Thanks! Hi, my name is David, and among other things, I am a hobbyist game developer. I've been following the Forums for a while, and finally finished a game so I'm diving in and introducing myself.I have been playing games as long as I can remember. When I was 10 or 11, I saved up enough money to buy a Vic-20, and taught myself to program, first in basic, then Assembly. Back in those days, we bought magazines with the source code, typed them in and then ran them to play games, before I could afford a cassette(!) tape reader.EverThe objectives of this contract are as follows: 1) determine the prevalence of retrovirus seropositivity in first time blood donors; 20 determine the rate of retrovirus seroconversion in repeat blood donors as a measure of incidence of infection; 3) ascertain risk factors for antibody-positive donors; 4) characterize the blood donor population by geographic location, age, sex, race/ethnicity, and donation history to permit analysis of prevalence, incidence, and risk factors; 5) identify recipients of retrovirus-positive blood units and conduct clinical and laboratory follow-up of these recipients to determine the transmissibility of these agents via transfusion; and 6) establish blood specimen repositories for long-term storage of specimens from study donors and recipients for future testing.


behave like a fluid with equation of state $\omega=-1$ [@Brax:2004qh; @Brax:2004px]. In this way the chameleon is a natural explanation for dark energy.

The paper is organised as follows. Section \[homogeneous\] shows how photons mix with chameleon particles and gives the probability of a photon converting into a chameleon in a homogeneous magnetic field. Section \[varying\] discusses the probability of conversion as the particles pass through a magnetic field made up of many randomly oriented domains and section \[supernova\] explains how photons can be converted into chameleons in the interior of a supernova, resulting in a flux of chameleons at the surface. Then Section \[sec:brightening\] describes how this can account for the brightening of the image of the supernova. In Section \[CMB\] I show that chameleon-photon mixing is inreactions driving the explosion of the supernova and that the photons are emitted uniformly throughout the volume of the supernova. Peak luminosity occurs about 10 days after the start of the explosion.

The explosion of a supernova is homologous and so the magnetic field obeys $$\frac{B_{SN}(t)}{B_{WD}}=\left(\frac{R_{WD}}{R_{SN}(t)}\right)^2$$ where $B_{SN}(t)$ and $R_{SN}(t)$ are the magnetic field and radius of the supernova at time $t$ after the start of the explosion and $B_{WD}$ and $R_{WD}$ are the magnetic field and radius of the initial white dwarf. Models of the magnetic field of a white dwarf vary, but all predictions lie in the range $10^5\mbox{ G} \lesssim B_{WD} \lesssim
10^{11}\mbox{ G}$. The size of the mean free path of photons at peak luminosity of the supernova is also not well known but is expected


improving the search sensitivity by a factor of ten during the 1990s and by making surveys of promising bright candidates using the Very Large Array (VLA) and ATCA. Our observation of NGC4945 reported here was the third detection made in our ATCA survey for H92$\alpha$ emission. The other two detections from this survey (NGC3256 and the Circinus galaxy) were reported by [@roy05] and [@roy08]). NGC4945 has proven to be the strongest known extragalactic RRL emitter on the sky.

We give velocities in the heliocentric frame using the optical velocity definition throughout this paper.

Observations
============

We observed NGC4945 with the ATCA simultaneously in the lines H91$\alpha$ and H92$\alpha$ with two orthogonal linear polarizations. The observing parameters and results are summarized in Table 1.

Calibration and imaging were done using the AIPS software using![ Top: ATCA first-moment image of H91$\alpha$ + H92$\alpha$ emission showing rotation. Beamsize is $1.4'' \times 1.2''$. Middle: H91$\alpha$ + H92$\alpha$ rotation curve along the major axis of the line-emitting region (PA = $47^{\circ}$). Resolution is $1.3'' \times 36$kms$^{-1} $. Bottom: Rotation curve from the best-fit dynamical model described in Sec. 5. ](13926fig2c.eps "fig:"){width="7cm"}

The position-velocity diagram (Fig. 2) shows a well resolved symmetric structure indicating undisturbed rotation with a flat rotation curve extending in close to the nucleus. The rotation curve is modelled in Sec 5.

Modelling Line Formation in the Ionized Gas
===========================================

Two types of models have been considered for the RRL emission from the nuclei of external galaxies: one based on a uniform slab of ionized gas and the other based on a collection of compact H II regions.


on the high resolution 8.4GHz image. The IRAS $60\,\mu$m and $100\,\mu$m flux densities yield a far-infrared (FIR) star formation rate of 4.1$M_\odot$yr$^{-1}$. These estimates agree well with the star formation rate estimated from the RRL emission of 2$M_\odot$yr$^{-1}$ to 8$M_\odot$yr$^{-1}$. The H$\alpha$ and U-band-based star formation rates were not estimated due to the extreme absorption in the optical band. The supernova rate estimated by [@forbes98] from the 4.8GHz flux density is 0.23yr$^{-1}$, and from the \[Fe II\] flux is much lower at 0.005yr$^{-1}$. These can be converted into star-formation rates following [@fukugita03], yielding rates of 19$M_\odot$yr$^{-1}$ and 0.4$M_\odot$yr$^{-1}$. These bracket the range we estimated from the RRL emission.

Our RRL-based SFR estimate assumed no dust absorption between the OB stars and the HII regions producing the RRL emission. The
What’s the deal with AirPower? - bluedino
https://daringfireball.net/linked/2018/06/13/airpower-claim-chowder
======
LeoPanthera
It's tempting to speculate that they're having difficulty with the technology,
but "iMessage in the cloud" was also announced at WWDC 2017, and was released
just days before WWDC 2018, so it is (perhaps?) more likely that Apple is
having more systemic problems internally developing things.

~~~
akmarinov
Same thing with the HomePod, it was announced in June and then it was shipped
8 months later.

------
jonny_eh
Couldn't this post have just been a tweet?


Chromatographic resolution of the rod pigment from the four cone pigments of the chicken retina.
Chicken rod and cone pigments are chromatographically resolved using a combination of stepwise elution from a concanavalin A affinity column and a secondary ion exchange purification. The rod pigment rhodopsin and the cone pigment iodopsin are purified to homogeneity. There is a partial separation of three other cone pigments: chicken green, chicken blue, and chicken violet, making clear that this is at least a tetrachromatic cone system.and challenge to the concept of colour as race. And this was absolutely the case with Obama’s portrait. As I stood there, I thought: what does it mean that a woman who looks like me – with a nose, hair and features like mine – could exist in a space so populated with old white men? What does it mean that, up until Sherald unveiled the portrait of the first black First Lady of the United States, she had existed relatively under the radar? In what ways has Obama opened doors for Sherald and for other black women like me?

Here, Obama is pushing us to reckon with our own becomings – to realise our own story and to have the power to tell it

These questions lingered on my


up

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preferences at My ProfileMapping pseudouridines in RNA molecules.
Pseudouridine is present in ribosomal RNA, transfer RNA, tmRNA, and small nuclear and nucleolar RNAs. All are structured molecules. Pseudouridine is made by enzyme-catalyzed isomerization of specifically selected U residues after the polynucleotide chain is made. No energy input is required. Pseudouridine formation creates a hydrogen bond donor at the equivalent of uridine C-5. Therefore, a major role of pseudouridine may be to strengthen particular RNA conformations and/or RNA-RNA interactions because of this extra H-bond capability. Understanding the role of pseudouridine critically depends on knowledge of their location and number in RNA. The mapping method described here has greatly simplified this task and made it possible to survey many organisms. Procedures are described for mapping pseudouridines in large RNAs like ribosomal RNA and in


small RNAs like tRNA. The method involves carbodiimide adduct formation with U, G, and pseudouridine followed by mild alkali to remove the adduct from U and G but not from the N-3 of pseudouridine. This results in attenuation of primed reverse transcription resulting in a stop band one residue 3' to the pseudouridine on sequencing gels. Use of primers means that purified RNAs are not needed, only knowledge of its primary sequence, but limit the sequence scanned to 30-40 residues from the 3' end. A poly(A) tailing procedure is described that allows extension of the method to within a few nucleotides of the 3' terminus.and, surprise surprise, she plays a quicky, cute, likeable, girl-next-door. The show is about her character (Jess) as she moves in with three male roommates after she catches her boyfriend cheating on her within the first few minutes of the first episode.

Deschanel is funny and good in this role (of course, she's been playing this role for the past decade or so in movies) but the show would get stale and boring if it solely focused around her character. The reason the show works so well is because of her three roommates (well, really mainly two). Her roommates are Nick (Jake Johnson), Schmidt (Max Greenfield) and Winston (Lamorne Morris).

In the pilot episode, the black roommate was played by Damon Wayans Jr. who didn't continue with the show because


and -44/3.
1932
Find the common denominator of -71/4 and -53/40.
40
What is the smallest common multiple of 8 and 1317?
10536
Calculate the common denominator of -48/11 and 15/1169.
12859
Calculate the common denominator of 49/12 and 13/64.
192
What is the common denominator of 137/198 and -41/12?
396
Find the common denominator of 77/24 and 4/111.
888
Calculate the least common multiple of 126 and 99.
1386
What is the common denominator of -83/256 and 57/464?
7424
What is the lowest common multiple of 56 and 4816?
4816
Calculate the common denominator of 17/27 and -67/366.
3294
Calculate the common denominator of 29/210 and -1/84.
420
Calculate the common denominator of 4/143 and 155/1482.
16302
Calculate the common denominator of 4/7 and 73/544.
3808
What is the lowest common multiple of 4 and 4039?
16156
Calculate the smallest common multiple of 602 and 5719.
11438
What is the smallest common multiple of 30 and 18?
90
Calculate the lowestthat is defined by Unix. Root access and write protection are different.MoFo gives you root access but does not disable write protection. I don't need write protection disabled as long as I have free WiFi tether, TiBu and Adaway. There was one other app I wanted - one that lets you selectively control app permissions but I forget the name of it.Greenify is pretty nice from what I have read and I believe that on the DT they have it working, idk for sure, but you can read over there if you want to know more.


Introduction {#Sec1}
============

Primary liver cancer remains a major problem for all health care systems worldwide and is associated with a significant clinical, economic, and psychological burden. Hepatocellular carcinoma (HCC) accounts for \~90% of cases of non-metastatic tumors of the liver.^[@CR1]^ During the past decades, research has shed light on the epidemiology, risk factors, and molecular and genetic profiles of HCC‚ contributing to the evolution of strategies for prevention, surveillance, early diagnosis, and treatment.^[@CR2],[@CR3]^ Liver resection, ablation, and liver transplantation are potentially curative but require diagnosis at a sufficiently early stage. Unfortunately, a significant proportion of HCC patients present with intermediate and advanced stage disease often, despite diligent surveillance, and curative treatments are frequently not possible.^[@CR4]^ In these patients, systemic therapy remains essential and its pivotal role and potential havea clinically significant improvement in prognosis.^[@CR106]^ This is supported by the demonstration that the new liver reserve function biomarker, albumin-bilirubin grade (ALBI),^[@CR107]^ successfully identified regorafenib candidates and that in the selected cohort a median OS of 15.6 months was achieved compared with 6.8 months for non-candidates.^[@CR108]^ Even in patients not eligible for regorafenib, the ones with an ECOG-PS score of 0, the absence of MVI, and TTP (time to progression) ≥4 months could still have acceptable postprogression survival.^[@CR109]^ Long-term treatment with regorafenib has also been shown to reduce angiogenesis and improve portal hypertension (PHT) and acute administration ameliorates portal haemodynamics, suggesting that it may be especially suitable for patients with PHT and preserved liver function.^[@CR110]^

Cabozantinib {#Sec7}
------------

Cabozantinib is another small molecule inhibitor of the tyrosine kinases which are implicated


which may act as potential targets,^[@CR185]^ it is reasonable to believe that with an appropriate and well-designed trial protocol it should be possible to identify and validate specific biomarkers which will predict the response to specific targeted agents. Thus, we can prevent the use of treatments which can have no therapeutic effect, and may be associated with significant, avoidable toxicity.

Drug resistance of targeted therapy for HCC {#Sec12}
-------------------------------------------

Drug resistance remains the principle cause of treatment failure during the use of targeted therapies^[@CR200]^ and tumor heterogeneity and clonal evolution are the underlying mechanisms (Fig. [2](#Fig2){ref-type="fig"}), with the former mainly involved in primary resistance and the later acquired resistance.^[@CR201]^ HCC is a remarkably heterogeneous disease exhibiting inter-patient heterogeneity, intertumoral heterogeneity among multifocal tumors and intratumoral heterogeneity (ITH) within tumors. This heterogeneityundesirable as it confounds data collection at best and potentially exposes the responsible clinician to criticism especially where serious adverse events occur.

Conclusion {#Sec14}
==========

An iterative approach to targeted therapy has provided a wealth of data and encouraging results particularly in those patients where resistance to sorafenib develops. Although the understanding and management of HCC has changed dramatically due to the extensive basic and clinical research which has occurred over the last decade, HCC sadly remains a devastating disease which has a ubiquitous, enormous impact on health care systems across the world. The advances over this period however mean that patients can be comforted by the knowledge that there is a huge international effort underway from oncologists, hepatologists, and basic scientists to fully understand the mechanisms which are providing more


the group's claims as "invention" and "exaggeration".

He said Mr Rahman did not want to be elected as a result of fraudulent activity and had been anxious that electoral law was observed.

Mr Penny said: "He has consistently called for anyone with suspicion of malpractice to report them and has been a public proponent of reforms to the postal voting system."Residence Inn Provo

SpringHill Suites Provo

SpringHill Suites Provo

Provo

Provo sits on the banks of Utah Lake, surrounded by the stunning Wasatch Mountain range. The city is only 45 miles south of Salt Lake City and offers visitors the most stunning Utah attractions.Guests can start exploring the surrounding area by visitingProvoCanyon, famous for rock climbing and hiking. Here, you will find the 600-foot-tall Bridal Veil Falls, located in the southern end of the canyon. Families will enjoy the Provo Beach, a park with an indoor wave machine, to make visitors feel like they are really riding the waves. Those looking to discover Utah’s art and heritage have manythings to do in Provoas well. The Brigham Young University houses many museums and galleries, including the Museum of Peoples and Culture with anthropological,


 if (ret) {
            fprintf(stderr, "ERROR: Write failed!\n");
            return ret;
        }
    }

    /* Reset to factory defaults */
    if (want_bits & WANT_DEFAULTS) {
        ret = CopyDefaultsCalib();
        if (ret) {
            fprintf(stderr, "ERROR: Factory reset failed!\n");
            return ret;
        }
    }

    /* Read */
And I'm not saying don't be sad. But it's not unavoidable, it's not something that was bound to happen no matter what. Unlike the separation between the singer and Tuesday was unavoidable due to something specific about her nature.

This is a tactic that I've seen used very effectively lately on twitch, and I think I'm going to give it a try in the coming war. Simply put, it's a pretty standard gowiwi (although I bet gowipe would work), but once the troops hit the center and are getting attacked by the defenses opposite from the side the attack originated, 10-12 hogs are released to take out those defenses. If the defenses are already occupied by your main force, the hogs seem to be able to drop about 5


of them, which in turn preserves your main force. Anyway, I'm giving it a whirl this war, and I wanted to share it, and the clever name I came up with.

My father used to say that not playing to win is like sleeping with your sister. Sure she's a great piece of tail, with a blouse full of goodies, but... it's just illegal. Then you get into that whole inbred thing. Kids with no teeth who do nothing but play the banjo... eat apple sauce through a straw... pork farm animals.

Here's the thing. I don't think anyone could argue I'm not one of the people the most on the "focus on war" thing, and my thoughts on this kind of move are that we would need to considerQ:

C# - How to upload bigger files using FTP?

The code below works when i upload files around 12kb and below but for some reason anything above that size results in the program freezing and getting an error:
"The underlying connection was closed: An unexpected error occurred on a receive"
Is there something I am doing wrong?
using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Linq;
using System.Text;
using System.Threading.Tasks;
using System.Windows.Forms;
using System.IO;
using System.Net;

namespace FTP3
{
public partial class Form1 : Form
{
    public Form1()
    {
        InitializeComponent();
    }

    private void uploadFile(string filePath)
    {
        FtpWebRequest request = (FtpWebRequest)FtpWebRequest.Create("ftp://175.137.158.136" + "/" + Path.GetFileName(filePath));

        request.Method =


The dark Moon is in Scorpio this morning, and it will be the new moon by tomorrow afternoon. Meanwhile Mercury is moving more quickly into its conjunction with the Sun in Scorpio.

Yesterday we talked about the Mercury/Sun conjunction as an intimation of "sacred anxiety." Today let's talk about the word "security." Each fixed sign of the zodiac seems to value security, or stability, over all else. The form of security may vary from one sign to the next, but each fixed sign shares this common interest. For Scorpio the security has something to do with the physical, emotional, environmental, and instinctual levels of security. Do I feel an abiding sense of calm, trust, peace, depth, and safety in the environment, in my emotions and thoughts, in what's beingwe feel as though something has missed the mark (the same phrase underlying the word 'sin'). Whether that missing the mark is seen in small and daily events, or our idea of ourselves, or humanity or the cosmos itself, it seems that religious people are fundamentally trying to figure out how to deal with the loss, disappointment, or irritation of that gap...which appears to grow wider the more we focus upon it.

The ideas of conversion, salvation, redemption...to my mind each are similar to the word "sanctification." Each has at its roots the desire to "make holy" the world as it is, to forgive the world's inability to conform to some sense of mathematical perfection, or to embrace life on its own terms. When we live from this place


regulatory regions of genes has low correlation with their expression^[@CR4]^. Instead, it was argued that histone marks provide memory of recent transcriptional activity and that marks not coupled with active transcription are involved in transcriptional regulation processes (reviewed in^[@CR47]^).

Nonetheless, H3K4me3 marks are lineage-specific and are highly conserved in mammals, similar to the binding sites for transcription factors (which are determined by these marks) that are also organized in conserved domains^[@CR48],[@CR49]^. It is, thus, conceivable that in some cases histone marks could inform gene expression. To explore the correlation between histone marks and DEGs, we identified peaks overlapping DEGs. We found that 25 genes out of 377 DEGs were present in both datasets. These genes are associated with cell division (*Prim2, Rb1*), ATP binding and transcriptional regulation (*Nkx6-1, Zfp735*)For example, *Dmc1*, the gene important for meiotic DNA repair, is upregulated in CD-treated male progeny; the upregulation of *Dmc1* transcription was consistent with the increase in DMC1 foci in meiotic cells. We further suggest that changes identified in earlier cell types, both premeiotic and meiotic, could contribute to observed spermatozoa decline. It has been shown that exposure to CD causes decrease in epididymal sperm in rats without any changes in morphology of reproductive organs^[@CR60]^. It was suggested that any drug that affect spermatogonia could lead to defects in sperm maturation and spermatogenesis^[@CR61]^. We did not perform fertility tests, as studies have shown that even a 50--60% decline in sperm count will have no appreciable effect on fertility in mice (Schurmann *et al*., 2002; Zhang *et al*., 2006).

CD-mediated


from at least three cofounders from independent F0 pregnancies were used for most data points. Specifically, for RNA-seq analysis, germ cell and for meiosis analysis we used at least three independent biological replicates. For Chip-seq, we used two independent biological replicates from two treatment groups. For the analyses of F1 embryos (for ChIP), we pooled fetal testes from 5 gestated females to have one biological replicate for ChIP. Embryonic testes were pooled for ChIP- qPCR and RNA expression analysis. For the analyses of F1 adults, we used three independent treatments and the animals were randomized and used for ChIP and for RNA analysis. For RT-qPCR, we used 5 control and 5 F1 progeny males.

The mice were sacrificed via euthanasia using a CO~2~ gradient. The reproductive organs were dissectedQuantiTect Reverse Transcription (Qiagen) according protocol provided by manufacture.

RNA-seq library sequencing and data processing {#Sec25}
----------------------------------------------

A strand-specific library preparation protocol for RNA sequencing was performed using the sequencing technological platform at IGBMC, Strasbourg, France. We used three biological replicates for these experiments. The sequencing was performed in massive parallel sequencing paired-end mode, and the size of the sequencing tag was 50 bp.

Reads in FASTQ format were processed for quality control using the FastQC tool (<http://www.bioinformatics.babraham.ac.uk/projects/fastqc/>). To analyse differentially expressed genes, the quality-checked reads for each condition were processed using TopHat version 2.2.7^[@CR80]^. The reads were mapped to the reference genome \[*Mus musculus* Ensembl mm10 sequence\], and the alignment files were generated as BAM files. These files were used as the input for Cufflinks, a complementary method used to generate assembled


Q:

Server centered vs. client centered architecture

For a typical business application, should the focus be on client processing via AJAX i.e. pull the data from the server and process it on the client or would you suggest a more classic ASP.Net approach with the server being responsible for handling most of the UI events? I find it hard to come up with a good 'default architecture' from which to start. Maybe someone has an open source example application which they could recommend.

A:

It really depends on the application and the situation, but just keep in mind that every hit to the server is costly, both in adding load (perhaps minimally), but also in terms of UI responsiveness.  I am of the mind that doing things in JavaScript when possiblework on the Ontario, Simcoe and Huron railway, he was selected for five major Canadian railways including the Canadian Pacific Railway and the Intercolonial Railway (Hehner 9). The project of the CPR began and Fleming was appointed as Chief Surveyor of the CPR until he retired from the project in 1880 (Regehr 791). Fleming’s...

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...THOMAS (TOMMY) CLEMENT DOUGLAS
There are many significant Canadians that have done incredible things for Canada. But, in my opinion, the greatest of all is Thomas Douglas. He was born on October 20, in Falkirk, Scotland. Douglas is historically significant in Canada becauseThe most common calendar structure is the assembly of a plurality of pages which are stapled together along a center fold line. With the center fold line in a horizontal position, successive picture pages are positioned above the center line and successive calendar pages are positioned below the center line.
Conventionally, such calendars have a hole therethrough on the edge away from the center line. This hole permits hanging of the calendar on a suitable hanging projection, such as a nail or other similar projection. When supported in such a manner, the lower leaf can be raised and hung on the support, opening a new picture and new calendar month. Such a supporting structure is neither decorative nor secure. The calendar is unframed and thus presents an unfinished appearance.


There were, of course, persons who were
eager to detect impostors: and amongst them some of the most zealous
votaries of the occult arts--for example, Trittheim and the learned
Humanist, Conrad Muth or Mutianus, both of whom professed to have
regarded Faust as a fraud. But this did not imply any disbelief in the
possibility of the alleged pretensions. In the Faust-myth is embodied,
moreover, the opposition between the new learning on its physical side
and the old religious faith. The theory that the investigation of the
mysteries of nature had in it something sinister and diabolical which
had been latent throughout the Middle Ages was brought into especial
prominence by the new religious movements. The popular feeling that
the line between natural magic and the black art was somewhat doubtful,
that the one had a tendency to shade offasylum in Zürich. But they were fallen upon
on the way, and two were made prisoners, the rest, among them Joss,
escaping. Those of the conspirators who were taken prisoners behaved
heroically; not the most severe tortures could induce them to reveal
anything of importance. As a consequence, comparatively few of those
compromised fell victims to the vengeance of their noble and clerical
enemies. In Elsass they were not so fortunate as in Baden, many persons
being executed on suspicion. The Imperial Councillor Rudolph was
even sent into Switzerland to demand the surrender of the fugitives,
and two were given up by Schaffhausen. Joss's mistress was liberated
after three weeks, and she was suspected of having harboured him at
different times afterwards. The last distinct traces of him are to be
found in the Black Forest ten years later, during


but in this respect
narrow-minded Thomas Münzer, who in his open letter addressed to the
"Soft-living flesh of Wittenberg," scathingly denounces what he deems
his debauchery. It does not enter into our province here to discuss at
length the religious aspects of the Reformation; but it is interesting
to note in passing the more than modern liberality of Luther's
views with respect to the marriage question and the celibacy of the
clergy, contrasted with the strong mediæval flavour of his belief in
witchcraft and sorcery. In his _De Captivitate Babylonica Ecclesiæ_
(1519) he expresses the view that if, for any cause, husband or wife
are prevented from having sexual intercourse they are justified, the
woman equally with the man, in seeking it elsewhere. He was opposed to
divorce, though he did not forbid it, and recommended that a man should
ratherany attempt to overthrow the power of the
clergy and the monks, he had also an eminently political motive for
his action in what was, in some respects, the main object of his life,
_viz._, to rescue the "knighthood," or smaller nobility, from having
their independence crushed out by the growing powers of the princes
of the Empire. Probably more than one-third of the manors were held
by ecclesiastical dignitaries, so that anything which threatened
their possessions and privileges seemed to strike a blow at the very
foundations of the imperial system. Hutten hoped that the new doctrines
would set the princes by the ears all round; and that then, by allying
themselves with the reforming party, the knighthood might succeed in
retaining the privileges which still remained to them, but were rapidly
slipping away, and might even regain some


their consideration, the more
especially because it will afford us the opportunity for considering
other changes in that spirit of the age, partly diseased growths of
decaying mediævalism, and partly the beginnings of the modern critical
spirit, which also find expression in the literature of the Reformation
period.

FOOTNOTES:

[9] See Appendix B for this and an instance of a successful
imposture.

[10] _Sämmt. Werke_, xxxiii., 322-324.

[11] Quoted in Janssen, _Ein Zweites Wort an meine Kritiker_,
1883, p. 94.

[12] _Geschichte des Deutschen Volkes_, vol. ii., p. 115.

[13] Quoted in Janssen, bk. ii., 162.

CHAPTER III.

POPULAR LITERATURE OF THE REFORMATION.

In accordance with the conventional view we have assumed in the
preceding chapter that the Reichstag at Worms was a landmark in the
history of the Reformation. This is, however, only true as regards
the political side of the movement. The popular feeling wasthis pond, a great tempest
arises, which often devastates the whole neighbourhood. He also alleges
Prussia to be full of evil spirits.

Devilish changelings, Luther said, were often placed by Satan in the
cradles of human children. "Some maids he often plunges into the
water, and keeps them with him until they have borne a child." These
children are placed in the beds of mortals, and the true children are
taken out and hurried away. "But," he adds, "such changelings are
said not to live more than to the eighteenth or nineteenth year." As a
practical application of this, it may be mentioned that Luther advised
the drowning of a certain child of twelve years old, on the ground
of its being a devil's changeling. Somnambulism is, with Luther, the
result of diabolical agency. "Formerly," says he, "the <DW7>s, being
superstitious


To this summons Franz sent a characteristically
impudent reply,[21] and light-heartedly continued the campaign,
regardless of the warning which an astrologer had given him some time
previously, that the year 1522 or 1523 would probably be fatal to
him. It is evident that this campaign, begun so late in the year, was
regarded by Sickingen and the other leaders as merely a preliminary
canter to a larger and more widespread movement the following spring,
since on this occasion the Swabian and Franconian knighthood do not
appear to have been even invited to take part in it.

After an easy progress, during which several trifling places, the most
important being St. Wendel, were taken, Franz with his army arrived on
the 8th of September before the gates of Trier. He had hoped to capture
the town by surprise, and was indeedthe "great reformer"
will be seen later on when we find him pursuing a similar policy anent
the revolt of the peasants.

After the fall of the Landstuhl all Sickingen's castles and most of
those of his immediate allies and friends were of course taken, and
the greater part of them destroyed. The knighthood was now to all
intents and purposes politically helpless and economically at the door
of bankruptcy, owing to the suddenly changed conditions of which we
have spoken in the Introduction and elsewhere as supervening since the
beginning of the century: the unparalleled rise in prices, concurrently
with the growing extravagance, the decline of agriculture in many
places, and the increasing burdens put upon the knights by their feudal
superiors, and last, but not least, the increasing obstacles in the
way of the successful pursuit of the profession


intellectually. The modern idea of a town is that
of a mere local aggregate of individuals, each pursuing a trade or
calling with a view to the world-market at large. Their own locality
or town is no more to them economically than any other part of the
world-market, and very little more in any other respect. The mediæval
idea of a town, on the contrary, was that of an organisation of groups
into one organic whole. Just as the village community was a somewhat
extended family organisation, so was, _mutatis mutandis_, the larger
unit, the township or city. Each member of the town organisation owed
allegiance and distinct duties primarily to his guild, or immediate
social group, and through this to the larger social group which
constituted the civic society. Consequently, every townsman felt a kind
of _esprit de corps_with a number of our strategic partners to determine what ingredients in the rubber would cause discoloration—and those ingredients were eliminated.

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                                 3

2006, a portion of a building located at 65 rue de la Victoire,
in  which  Right  Management  leased  office  space,  collapsed,
seriously damaging part of the building as well as its under‐
ground garage. Right Management’s offices and furnishings
were not physically damaged, but they were rendered whol‐
ly  inaccessible  because  the  building  could  no  longer  be  oc‐
cupied by order of the Parisian Department of Public Safety.
Eventually,  Right  Management  relocated  its  business,  with‐
out having gained access to its old office space and the fur‐
nishings  therein;  it  therefore  incurred  replacement  costs
when it furnished and improved its new office space. In the
meantime,  Right  had  lost  income  and  incurred  expenses
from the interruption of its business operations. This dispute
arises from Manpower’s claims for insurance coverage for its
(Right’s) various losses.
    Two  insurance  policies  govern  the  coverage  dispute:  a
difference in conditions policy—the “master” policy—issued
by  ISOP  and  covering  Manpower’s  operations  worldwide,
and  a  local  policy  that  was  issued  by  AIG‐Europe,  ISOP’s
French  affiliate,  to  Right  Management  as  the  insured.  In
simple terms, the local policy provides the first line of cover‐
age, and the master policy fills in the gaps by providing ex‐
cess  coverage  over  the  local  policy’s  limits,  or  by  covering
specific  losses  that  are  not  insured  under  the  local  policy.
Therefore, coverage under the master policy is triggered on‐
ly when a given loss is not covered in full by the local policy,
and the insured must exhaust coverage under the local poli‐
cy before making any claim under the master policy. The lo‐
cal  policy  itself  comprises  “general  conditions,”  which  pro‐
vide                                       No. 12‐2688

use of the leased space. Manpower argued that any damage
to  these  features  that  caused  its  operations  to  stall  or  cease
triggered  the  coverage  under  the  master  policy’s  general
business  interruption  provision.  ISOP  conceded  that  there
was some damage to the common areas of the building, but
maintained  that  Right’s  offices  were  unharmed,  and  there‐
fore  could  have  been  used  but  for  the  order  of  the  civil  au‐
thorities that prohibited Right from occupying them.
    In its November 3, 2009, opinion, the district court sided
with Manpower. Parsing the expert testimony submitted by
both  sides,  the  district  court  concluded  that  “the  evidence
establishes  that  the  collapse  rendered  the  entire  [building]
unstable, at least for a period of eight to ten weeks following
the collapse,” during which temporary measures were taken
to  ensure  the  building’s  stability.  Therefore,  at  least  until
temporary repairs were completed, it was the collapse itself
that prevented Right from using its offices, and the order of
the Department of Public Safety “merely confirmed that the
collapse rendered the entire building unstable.” Accordingly,
the  district  court  held  that  the  $500,000  sublimit  on  losses
caused by lack of access by order of civil authorities did not
apply, and that “Manpower is entitled to reimbursement for
any business interruption losses it sustained between the col‐
lapse and the time the necessary repairs could have been, or
were,  completed,  up  to  $15  million.”  The  business‐
interruption  coverage  further  entitled  Manpower


court  declined  to
evaluate Sullivan’s calculation of non‐continuing expenses—
the  other  variable  in  the  equation  of  the  business  interrup‐
tion loss.
    Manpower moved for reconsideration of the decision, ar‐
guing  that  the  district  court  had  misunderstood  Sullivan’s
analysis in numerous ways. It further argued that the district
court misapplied Rule 702 and Daubert by taking out of the
jury’s  hands  the  questions  whether  Sullivan  reasonably  re‐
lied  on  the  testimony  of  Right  Management  executives  and
whether a growth rate derived from a five‐month period was
reasonable. In the alternative, Manpower requested that the
district  court  accept  a  supplement  to  Sullivan’s  report,  con‐
sisting  of  an  affidavit  in  which  Sullivan  further  explained
parts  of  his  expert  report.  For  example,  he  attested  that  he
“did more than simply select the 5‐month growth from one
No. 12‐2688                                                          11

year  to  the  next,”  citing  a  table  in merged  into  the  final  judgment  entered  on
June  20,  2012.  See  Kunik  v.  Racine  County,  106  F.3d  168,  172‐73  (7th  Cir.
1997). We find it unnecessary to separately discuss each decision, as the
district court’s rationale remained constant.
No. 12‐2688                                                           17

gues,  however,  that  the  district  court  abused  its  discretion
when it barred Sullivan from testifying. We agree that Sulli‐
van’s opinion—although not bulletproof—is sufficiently reli‐
able  to  present  to  a  jury  and  that  in  excluding  Sullivan’s
opinion, the district court exercised its gatekeeping role un‐
der Daubert with too much vigor.
   Rule 702, governing the admissibility of expert testimony,
provides:
          A  witness  who  is  qualified  as  an  expert  by
          knowledge,  skill,


S.L. "La Canastita" (Lucena del Puerto, Huelva, Spain). Plants and greenhouses were handled according to regular agricultural practices (Ramos-Solano et al., [@B42]). Plants were grown in Huelva (South Eastern Spain) from September 2014 to February 2015 under "winter cycle." Shortly, plants undergo an artificial cold period before transplant to greenhouses in order to start their regular cycle. Blackberry cycle has three stages: vegetative, flowering and flowering-fruiting; the duration of these stages is variable depending on the transplant moment, and each average one third of the plant\'s life. In this experiment, plants were transplanted at the end of September, flowering in November and fruiting in January when flowers, green, red and black fruits are present in the plants at the same time. Fruits were sampled in red stage. Leavesto the Hit Blast, and annotation selected from this GOs those with good statistical support). Annotation was made with an annotation cutoff of 55, and a GO weight of 5.

### Expression levels

Gene expression levels were calculated using Fragments Per Kilobase of transcript per million Mapped reads (FPKM) method. The formula used is FPKM= 10^9^ ^\*^ C/(N ^\*^ L), where C is the number of mappable reads that fell onto the gene\'s exons, N the total number of mappable reads in the experiment and L the number of base pairs in the exon. The log~2~ (fold-change) is the log-ratio of a gene\'s or a transcript\'s expression values in two different conditions. The log~2~ fold change is used to confirm the significance of the differential expression between the different samples


Total anthocyanins

Total anthocyanins were quantitatively determined through the pH differential method described by Giusti and Wrolstad ([@B21]). Extracts were diluted in pH 1 buffer (0.2 M KCl) and pH 4.5 (1M CH~3~COONa) in 1:15 proportion. After that, absorbance was measured at 520 and 720 nm respectively, in a UV-Visible spectrophotometer (Biomate 5). A cyanidin-3-glucoside calibration curve was made (*r* = 0.99). Results are expressed in cyanidin-3-glucoside equivalents per 100 g of fresh weigh (FW). All samples were measured in triplicate.

Results {#s3}
=======

Transcriptome sequencing and assembly
-------------------------------------

To construct a *de novo* transcriptome database, six mRNA libraries were generated by Illumina sequencing, three from leaves and three from red fruits of *Rubus* spp. cv. Loch Ness.

Table [2](#T2){ref-type="table"} summarizes mapping results. In addition to these, it also shows the total number of readsby colorimetry (Table [3](#T3){ref-type="table"}) and identified by HPLC-MS (Figure [10](#F10){ref-type="fig"}). Red fruits contained 560 mg gallic acid equivalents (total phenols), 34 mg catechin equivalents (total flavonols), and 108 mg cyanidin-3-glucoside equivalents (total anthocyanins). Leaves showed 1,876 mg gallic acid equivalents, 296 mg catechin equivalents and 55 mg of cyanidin-3-glucoside equivalents. All results are expressed per 100 g fresh weigh. In summary, contents in leaves as compared to fruits were as follows: total phenolics were three-fold in leaves, while total flavonoids were six-fold in leaves and anthocyanins were two-fold in fruits.

######

**Quantification of total phenolics, flavonols, and anthocyanins in blackberry fruits and leaves**.

  **Sample**   **Total phenols mg gallic acid equivalents/100 g fresh weigh**   **Total flavonols mg catechin acid equivalents/100 g fresh weigh**


        --      **--**

*Peaks corresponding to the aglycon moiety*.

*ND- non detected*.

Due to the lack of commercial standards, most peaks have not been identified and no information about these unknown compounds has been provided. However, MS fragmentation in source has helped us to establish a tentative identification for most of the significant peaks by comparison with bibliography. Thus, caffeoyl-*O*-hexosides (*Rt* = 1.0--3.3 min) with a \[M-H\]^−^ ion at *m/z* 340.9 and \[M+Na\]^+^ and \[M+K\]^+^ adducts at *m/z* 365.0 and *m/z* = 381.0 respectively were found. Many caffeic acid-O-dihexoside and other caffeic acid derivatives were also found mainly in leaves (*Rt* = 20--45 min) with \[M-H\]^−^ ion at *m/z* 503.1, and chlorogenic acid was identified only in fruits (Table(Figure [9](#F9){ref-type="fig"}).

The higher expression of the activating flavonol biosynthetic pathway transcription factor genes in fruit as compared to leaves (Figure [9](#F9){ref-type="fig"}; *RuMYB*1, *RuMYB*3, and *RuMYB*5) is consistent with the massive synthesis of anthocyanin precursors in fruits that is eventually going to take place during ripening. *RuMYB1, RuMYB3*, and *RuMYB5* are positive regulators of *RuDFR, RuANR*, and *RuLAR*, leading to increased catechin synthesis, precursors of proanthocyanidins, that are accumulating in fruits (Table [4](#T4){ref-type="table"}). *RuMYB1* encodes a homolog of *FaMYB10*, which plays a major role in the regulation of anthocyanin and phenylpropanoid metabolism during ripening of *Fragaria x ananassa* fruits (Kadomura-Ishikawa et al., [@B27]). *RuMYB5* is homologous to *AtMYB5* in *Arabidopsis*, and the *AtMYB5* protein interacts with *TTG1* and *TT2*, two important transcription factors regulating the proanthocyanidin biosynthetic pathway (Baudry