benefits. Three were hospitalized as a result of the beatings which were reported in the media on April 21-22. On November 28, in Almaty, two unidentified men assaulted opposition activist Andrei Grishin, who published a newspaper article critical of a new museum dedicated to President Nazarbayev shortly before the incident. The attack apparently was politically motivated. Law enforcement authorities and anonymous telephone callers reportedly warned Grishin several times before the assault to stop his political activities. The assailants, who reportedly told Grishin that he deserved the attack, cut off Grishin's hair, doused him with oil paint, and left him unconscious. They did not rob him. No arrests were made in the case by year's end. Opposition activist Aleksei Martinov was detained on suspicion of theft of computer parts(3-hour) and long (72-hour) detentions for "suspicion" are used widely.

A bail system exists, but, according to the General Prosecutor's Office, only 28 out of the 26,598 persons detained in the first 8 months of the year were released on bail.

According to the Constitution, every person detained, arrested, or accused of committing a crime has the right to the assistance of a defense lawyer from the moment of detention, arrest, or accusation. This right generally is respected in practice. Human rights activists allege that members of the security forces have pressured prisoners to refuse the assistance of an attorney, sometimes resulting in a delay before the accused sees a lawyer. The Government's reluctance to provide a lawyer is partly attributed to a shortage of funds to pay court-appointed lawyers


of the local courts may be appealed to the oblast-level courts, while those of the oblast courts may be appealed to the Supreme Court. There is also a military court. Although they do not currently exist, specialized and extraordinary courts also can be created--for example, economic, taxation, family, juvenile, and administrative courts--which would have the status of oblast and local courts.

The Constitution and the law establish the necessary procedures for a fair trial. Trials are public, with the exception of instances in which an open hearing could result in state secrets being divulged, or when the private life or personal family concerns of a citizen must be protected.

According to the Constitution, defendants have the right to be present, the right to counsel (at public expense if needed), andhuman rights activists believed that the Government used the auctions in the past to harass and even eliminate independent media. The Government continued its discussion of a 50 percent Kazakh language content in broadcasting, and threats of selective enforcement of this requirement remain a problem. However, there were no reports during the year of the Government closing stations or failing to renew their licenses if they were not in conformity with the 50 percent rule, despite government threats in 1998 to do so.

There was no further action by the Prosecutor General concerning the legality of the frequencies auction in 1997. Nor was there any response from the Prime Minister to the Prosecutor's request for a ruling on the law guiding the auctions. There was no law passed on


Orleu opposition movement. Some television editors claimed that they were told categorically not to cover certain opposition candidates. Azamat claimed that state television and radio denied its candidates the free air time normally available to all candidates. An RNPK candidate, Twenty-First Century newspaper editor Bigeldy Gabdullin, charged correctly that his free broadcast was not shown in his home constituency of Talgar.

The Constitution provides for the protection of the dignity of the President and the law against insulting the President and other officials remained on the books. Labor Movement leader Madel Ismailov served 1 year in prison for violating the law (see Section 1.e.). Several laws control advertising in the mass media. One law restricts alcohol and tobacco advertising on television. The new media law prohibited violence and alland strikes" that upset social and political stability.

According to the law, organizations must apply to the local authorities for a permit to hold a demonstration or public meeting at least 10 days in advance, or the activity is considered illegal. In some cases, local officials routinely issued necessary permits. However, human rights activists complained that complicated procedures and the 10-day notification period made it difficult for all groups to organize public meetings and demonstrations. They reported that local authorities, especially those outside of the capital, turned down the majority of applications submitted or refused to allow rallies to take place in central locations. An April 1998 amendment to the election decree that bars candidates for public office who have been convicted within the preceding year of administrative offenses


Under the law, members of unregistered parties may run for elected office as individuals, but not as party members.

In December 1998, leading government opponents headed by former Prime Minister and disqualified presidential candidate Akezhan Kazhegeldin began efforts to form the new Republican People's Party. The group held its first congress in Moscow to avoid government harassment directed at Kazhegeldin and other members of the opposition prior to the January presidential election (see Section 3). According to conference organizers, authorities at the Moscow hotel where the congress was to have been held denied the group access to conference facilities on the eve of the meeting. Organizers said that approximately 10 other Moscow hotels subsequently refused to allow the group to use conference facilities before organizers found a suitable location.Organizers of the congress credibly alleged that Kazakhstani authorities used influence with Russian officials to try to disrupt the congress. The party was registered by the Government prior to the parliamentary elections in October and several of its members became candidates in individual races. The other candidates running against the President in the January presidential election and against government-favored candidates in the October parliamentary elections complained that local officials throughout the country refused to allow them to rent public halls for political meetings.

The Constitution prohibits foreign political parties and foreign trade unions from operating. In addition the Constitution prohibits the financing of political parties and trade unions by foreign legal entities and citizens, foreign states, and international organizations.

c. Freedom of Religion

The Constitution provides for freedom of religion, and


entitled legally to carry out their work without government registration, in practice many local officials insist that they register. Registration requires an application submitted by at least 10 local citizens and is usually a quick and simple process. Some religious groups out of favor with the Government encounter difficulties registering in certain jurisdictions. These groups include Jehovah's Witnesses and some Korean Protestant groups, as well as Muslim and Russian Orthodox groups independent of the Mufti or Orthodox archbishop (the national leaders of Islam and Russian Orthodoxy). Foreign missionaries require state accreditation. There were no reports that the Government prohibited the activities of any religious group whose registration application it turned down.

Foreign missionary activity is authorized under law, but only when missionaries are accredited by the state. In practiceTajikistan, Uzbekistan, and other states. In September the National Security Council, which is chaired by the President, created a commission to develop policies to combat religious extremism. In June the chief of the KNB named the fight against religious extremism as a top priority of the internal intelligence service.

On July 14, a group of more than 100 armed special forces and police raided a camp outside Taraz where a Muslim group was holding a private religious study retreat. The authorities detained 70 group members, including, reportedly, a 6-year-old and 11 other minors. Group members alleged that the authorities beat all 70 detainees in jail. One minor reportedly suffered a broken nose; another detainee reportedly suffered broken ribs. Although some government officials publicly alleged that the group was terrorist,


the organization or its membership after the raids were publicized.

On May 19, the public prosecutor's office in Almalinskiy district of Almaty petitioned a city court to ban the Charismatic Evangelic Church of Christ. The petition was based on the alleged irregularities in the group's registration, its foreign pastor's legal status, and alleged violations of the law on family and marriage by the pastor. The city court dismissed the case on June 17. The prosecutor's office appealed the decision but lost the appeal.

The Government often invited the national leaders of the two largest religions, Islam and Russian Orthodoxy, to participate jointly in state events. Such appearances by the Islamic Mufti and the Orthodox Archbishop, often in the presence of the President, were intended to promote religious and ethnic harmony.been politically motivated and, government critics alleged, sanctioned by the Government. In October 1998, two gunshots of unknown origin were fired near Kazhegeldin on the eve of the press conference at which he announced his presidential candidacy. Unknown assailants beat his press spokesman, Amirzhan Kosanov, and one of his public relations advisers, Yelena Nikitenko (see Section 1.c.). Several days before the attack, officials of the Al-Farabi national university in Almaty forced Nikitenko to resign from the faculty because of her political work. Government officials alleged that the Kazhegeldin campaign staged all three attacks. Following the announcement of Kazhegeldin's candidacy, the then first deputy chairman of the KNB held an unprecedented press conference at which he made admittedly unsubstantiated allegations of financial malfeasance against Kazhegeldin. The tax authorities brought


Bureau for Human Rights and Rule of Law (formerly the Kazakhstan-American Bureau on Human Rights) are the most active of a small number of local human rights organizations. They cooperate on human rights and legal reform issues. Although these groups operated largely without government interference, limited financial means hampered their ability to monitor and report human rights violations. In November a fire destroyed the main office and all the archives of the Bureau for Human Rights in Almaty. The Almaty fire department concluded that arson was the probable cause of the fire and referred the case to prosecutors, who brought no charges before the end of the year. Some human rights observers complained that the Government monitored their movements and telephone calls.

The Civil Code requires NGO's to registerPhagocytic activities of hemocytes from the deep-sea symbiotic mussels Bathymodiolus japonicus, B. platifrons, and B. septemdierum.
Deep-sea mytilid mussels harbor symbiotic bacteria in their gill epithelial cells that are horizontally or environmentally transmitted to the next generation of hosts. To understand the immune defense system in deep-sea symbiotic mussels, we examined the hemocyte populations of the symbiotic Bathymodiolus mussel species Bathymodiolus japonicus, Bathymodiolus platifrons, and Bathymodiolus septemdierum, and characterized three types of hemocytes: agranulocytes (AGs), basophilic granulocytes (BGs), and eosinophilic granulocytes (EGs). Of these, the EG cells were the largest (diameter, 8.4-10.0 μm) and had eosinophilic cytoplasm with numerous eosinophilic granules (diameter, 0.8-1.2 μm). Meanwhile, the BGs were of medium size (diameter, 6.7-8.0 μm) and contained small basophilic granules (diameter, 0.3-0.4 μm) in basophilic cytoplasm, and the AGs, the


of cruelty
to-day; see that you do better to-morrow."

The prince turned sharply, but no one was to be seen; yet he recognised
the voice as that of Fairy Candide.

He followed her advice for a little, but presently he forgot, and the
ring pricked him so sharply that his finger had a drop of blood on it.
This happened again and again, for the prince grew more self-willed and
headstrong every day; he had some bad friends, too, who urged him on, in
the hope that he would ruin himself and give them a chance to seize the
throne. He treated his people carelessly and his servants cruelly, and
everything he wanted he felt that he must have.

The ring annoyed him terribly; it was embarrassing for a king to have a
drop of blood on his finger allat UE-specific transmission timings or using UE-specific orthogonal codes.
The time and rate scheduling scheme additionally controls the E-DCH transmission timings of UEs. The time and rate scheduling scheme schedules part of many UEs and allows for a rapid rate increase or decrease. For this purpose, scheduling information is delivered by an Absolute Grant (AG). The AG carries a maximum rate to a UE and the UE sets its maximum allowed rate to the AG.
For example, if the UE now has a maximum allowed rate of 16 kbps and a large amount of data to be transmitted from the UE exists, the Node B can allocate 568 kbps to the UE in the next scheduling period so that the UE can transmit at up to 568 kbps. The Node


will also perform standardized screening and evaluation of medical, neurologic, and psychiatric function of the control group. Demographically stratified normative data is necessary for testing the proposed hypotheses, and this will also be a valuable contribution to NP assessment. The core will provide topographic display and analyses of the NP data. The resulting regional or "lobar" values will be systematically related to anatomic and metabolic data across populations. In addition to supporting the clinical projects, it is anticipated that this core will generate improvements in methodology and new information on the regional brain systems underlying neurocognitive functions.Dr. Nussbaum herself did a content analysis of it.

In Miko Peled’s speech on March 23, 2015, he made more than a dozen references to “Israeli occupation” and “Israeli occupiers;” 19 references to “ethnic cleansing (of) Palestinian refugees”; depicted Israelis as “racists” nine times and as “oppressors” 17 times. Peled compared Israel to “South African Apartheid” five times; and portrayed Hamas as “resistance fighters” nine times—but called Israelis “terrorists” three times. Peled “demonized” Israel constantly, referred to Jewish “conspiracies” resorted to “double standards” as a way of “deligitimizing” Israel. He did not mention the Holocaust or the historical fate of Jews in Muslim countries.

Here are just some of Peled’s statements. According to Dr. Nussbaum:

Peled described “Gaza as an open air prison” (with no mention of Egypt). “They have no


postmasters" in the past.

Mrs Hamilton's fight echoes that of other postmasters seeking justice. She said issues in the Horizon system led to big discrepancies in her accounts, which she reported to her Post Office area manager.

But that manager could find nothing wrong with the system, and she was put in a situation where "you had to prove your innocence".

After a distressing two-year process, she eventually pleaded guilty to false accounting at Winchester Crown Court in order to escape a more serious charge of theft.

Image copyright Getty Images

She soon gave up her shop and found it difficult to get a new job due to her criminal record. She made ends meet by doing cleaning jobs for people in her village who didn't believe she was guilty.

"I couldn't get carJoseph County Public Library is considering closing its LaSalle Branch near the shopping center, citing financial woes and declining use of that branch.

A market analysis indicated the area will not support new large retail development, but some convenience retail would be feasible. A small pharmacy, a dry cleaner, a limited-service restaurant and a grocery store specializing in fresh produce were ideas mentioned.

Since the plan was released in September 2008, some positive changes have occurred:

-Bendix Family Physicians opened at 1010 N. Bendix Drive. Residents had indicated a need for medical services in the area.

-The Urban Garden Market operates near LaSalle Square on summer Saturdays, providing a place for residents to buy fresh produce and other food.

-LaSalle Square was added to the Airport Economic Development Area tax incremental financing district,


of the land.

Goals by 2018: Encourage more use of the nearby industrial areas; create a public plaza in the center of LaSalle Square; encourage retail along Bendix; demolish the existing St. Vincent de Paul building and the LaSalle Square plaza except for the church; and allow a residential developer to build new homes around the plaza.

Within 20 years, the plan recommends working with nearby residents to develop such possibilities as a community center and/or a community college satellite campus.

Jeff Vitton is a community development planner for South Bend who is working on the LaSalle Square plan. He notes the plan is for 20 years, and change won't occur overnight.

"There is a commitment to move forward. We want to rededicate streets through the plaza. That should help spur morepolyphagous shot hole borer, or PSHB, an unusually-adaptable, 2-millimeter-long beetle indigenous to Vietnam. Although tiny, the invasive beetle carries a fungus that grows inside trees, causing a disease called Fusarium dieback. Fryer, who now runs websites aimed at helping fight the plague, reckons that the beetle-fungus combination has already infested well over 100,000 of Johannesburg’s trees and is on track to damage or kill millions more, partially de-greening the city for at least a generation. The impact of what scientists call the shot hole borer-Fusarium dieback (SHB-FD) complex could extend to air quality and climate. Trees reduce air pollution and can be powerful moderators of the urban heat island effect, caused by asphalt, concrete, and brick absorbing solar energy and radiating it as heat. By killing a large


dead and dying trees. The cut wood is a valuable asset and is taken back to poorer neighborhoods, some of which lack electricity, as firewood or sold back into wealthier areas as barbecue fuel. (South Africans are extremely fond of wood-fired barbecues, known as braais.) Thus SHB-FD has been transported back and forth across the Johannesburg metro area and far beyond, and is now threatening tens of thousands of trees planted at government expense to green the poorer, historically black, areas of the city. A major challenge in protecting urban trees in general is that they fall into institutional cracks. Funding is available from commercial forestry and agriculture to study and combat invasive pests, and conservation authorities deal with pests in national parks and nature reserves. But urbanKnow Why We Are The Best Carpet Cleaning Company in Mabank TX

Among all the furnishings in the home, the carpet faces the most direct traffic which contributes to dirt accumulation and wears and tear. Hence, it is essential to keep the carpet clean and well maintained to not only keep it looking new but also to prolong its life.

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Beyond the


Amazon Prime.

You can also hover over the green button and click the "View Price History" link to see when the prices were at their highest and lowest for each seller, and what the prices were. To download the Chrome extension or Firefox add-on, check the links below.

Hover Hound | Chrome Web Store

Hover Hound | Firefox Add-Ons via Ghacksaccurate, complete picture of how, and when, requirements growth occurred.

It's easy to get sucked into the "just one more feature" maelstrom, but by tracking requirements you can get a clearer picture that "just one more feature" is really the fifteenth new feature added this month.

#### Maintain a Glossary

As soon as you start discussing requirements, users and domain experts will use certain terms that have specific meaning to them. They may differentiate between a "client" and a "customer," for example. It would then be inappropriate to use either word casually in the system.

Create and maintain a _project glossary_ —one place that defines all the specific terms and vocabulary used in a project. All participants in the project, from end users to support staff, should use the glossary to ensure


Our luxury bed and breakfasts all offer luxury guest rooms with private bathrooms, hosted evening pre dinner drinks and canapés and of course regionally inspired gourmet breakfast each day. Our luxury bed and breakfasts paint a vivid picture of your destination in a very short time with world-class professional hospitality and knowledge. Perfect for self drive touring, our luxury bed and breakfasts are all 5 star and like no other experienced in the world.

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Private Hotels

Small is beautiful, and whether you are seeking relaxation, culture, adventure or pure indulgence everyone of our carefully selected portfolio of small private hotels will be the perfect place to base yourself to discover, Our World. All privately owned these full service small hotels, are theSchauer, J., and Spence, J., concurred.
 CARTER, J.
 I reluctantly concur in the judgment, but because of the rule set forth in Chastain v. Superior Court, 14 Cal.App.2d 97 [57 P.2d 982], Briggs v. Superior Court, 215 Cal. 336 [10 P.2d 53], and Evans v. Superior Court, 107 Cal.App. 372 [290 P. 662], I can see no escape from the conclusion reached by the majority.
 I feel, however, that when a trial judge, sitting without a jury, decides a case in favor of one of the parties litigant as indeed he must, the only inference to be drawn therefrom is that he believed one side and disbelieved the other. This court, or an appellate court, later reverses the judgment and the cause is remanded for a new trial.


Dussich’s janitorial supply company from inserting itself into a much larger five-year, $5.9 million contract for more of the bags — thanks to a tailor-made city proposal for bids.

A few months after the Parks Department’s trial run of Mint-X, city officials took steps to ensure their agencies were heavily stocked with them for years to come by issuing a request for trash bags that have been officially “registered” with the US Environmental Protection Agency “to ward off rodents.”

Mint-X, its site proclaims, is the “world’s only EPA-registered, rodent-repelling trash bag.”

So when it came to the bidding process, JAD submitted a proposal to sell those bags directly to the city, as well as to provide other trash-can liners. As it turns out, the Mint-X maker lost out to a New  * Constructor.
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p53 reactivating drugs including DNA damage^[@CR18]^, endoplasmic reticulum (ER) stress^[@CR19]^ and an imbalance in glutathione (GSH) vs. reactive oxygen species (ROS) production^[@CR15]^. These studies suggest that characterization of downstream mechanisms of p53 reactivation agents may allow for rational selection of patients for treatment and/or improve design of drug combinations encompassing p53 activators.

Multiple cellular stresses activate the integrated stress response (ISR) to globally suppress protein synthesis (reviewed in ref. ^[@CR20]^). This is chiefly achieved via the phosphorylation^[@CR21]^ of the alpha subunit of the eukaryotic translation initiation factor 2 (eIF2α) which delivers initiator tRNA during translation initiation in a ternary complex (TC) with GTP^[@CR21]^. Upon initiator tRNA delivery, eIF2-GTP is hydrolyzed to GDP and subsequently recycled by eIF2B which acts as a guanine nucleotide exchange factor (GEF) for the next1.0% Triton X-100, 0.5% sodium deoxycholate, 0.1% SDS, 50 mM Tris pH 8.0 \[Sigma-Aldrich\]). The lysate was centrifuged for 10 min at 20.000 rpm in a tabletop centrifuge and 15 µl of the supernatant was spotted on a glass fiber filtermat (Filtermat B, Perkin-Elmer). The filtermat was subsequently washed twice in 10% Trichloroacetic acid (TCA) and once with ethanol:acetone (50:50) for 10 min each and dried overnight. A melt-on scintillator (MeltiLex, Perkin-Elmer) was applied to the filtermat and counts per minute were monitored using a microBeta plate reader (MicroBeta2, Perkin Elmer).

ROS detection using CellROX {#Sec6}
---------------------------

Endogenous ROS levels were detected using the CellROX Deep Red Reagent (C10422, ThermoFisher Scientific). MCF7 cells were grown to 70% confluency prior to 16 h incubation with 5 µM N-acetyl cysteine with or without 1 µM RITA added during the last 4 h.


treated with vehicle (DMSO) or 1 µm RITA in presence or absence of 5 mM NAC. **c** Polysome-tracings of MCF7 WT cells treated with vehicle (DMSO) or 1 µM RITA in presence or absence of 5 mM NAC for 8 h. **d** Western blotting of indicated proteins using extracts from sh-control and *sh4EBP1* MCF7 cells. **e** Representative polysome tracings of sh-control. and *sh4EBP1* MCF7 cells treated with vehicle (DMSO) or 1 µM RITA for 8 h. **f** Quantification of amount of efficiently translated mRNA from polysome-tracings normalized to the mean of vehicle (DMSO) treated sh-control MCF7 cells (*n* = 2). **g** Western blot for indicated proteins using extracts from MCF7 WT cells treated with vehicle (DMSO), 1 µM RITA or 0.25 µM Torin1 for 8 h

The mTOR pathway is a major regulator of protein synthesis and integrates multiple internal andmore potent pro-apoptotic and antineoplastic effects relative to using RITA alone. A similar effect may account for the improved activity of RITA in increasing radio-sensitivity of cervical cancer cell lines treated with RITA^[@CR55]^.

Overall, we provide evidence that RITA selectively induces PERK activity thereby effectively suppressing mRNA translation and inducing apoptosis in a *TP53*-independent manner. Moreover, these results point to the importance of the stress sensing eIF2α pathway in deciding the cellular fate in the context of RITA, and possibly other p53 reactivating agents, and show that modulation of this pathway may be exploited for therapeutic purposes.

Supplementary information
=========================

 {#Sec21}

Supplemental Figure 1 Supplemental Figure 2 Supplemental Figure Legends no marked changes Author contribution file

Edited by P. Bouillet

**Publisher's note** Springer Nature remains neutral with regard to jurisdictional claims in published maps


Image segmentation using hidden Markov Gauss mixture models.
Image segmentation is an important tool in image processing and can serve as an efficient front end to sophisticated algorithms and thereby simplify subsequent processing. We develop a multiclass image segmentation method using hidden Markov Gauss mixture models (HMGMMs) and provide examples of segmentation of aerial images and textures. HMGMMs incorporate supervised learning, fitting the observation probability distribution given each class by a Gauss mixture estimated using vector quantization with a minimum discrimination information (MDI) distortion. We formulate the image segmentation problem using a maximum a posteriori criteria and find the hidden states that maximize the posterior density given the observation. We estimate both the hidden Markov parameter and hidden states using a stochastic expectation-maximization algorithm. Our results demonstrate that HMGMMsolid tumors {#s3}
================================

Development and progression of solid tumors are in close relation with Warburg effect and aberrant glucose metabolism through glycolysis resulting in excess production of acidic byproducts whose efflux can deregulate the pH of tumor microenvironment (TME). In solid tumors, cancerous cells upregulate the expression of glucose transporter (GLUT-1) and some key enzymes and transporters (MCT-1, NHE-1, CA IX and H+ pump V-ATPase) to fulfill the high energy requirement. This deviant phenomenon provokes the efflux of protons into extracellular fluid (ECF), acidifying ECF (pH \~6.6), while the pH of cancer cells holds up to about 7.4.^[@R44]^ These anomalous phenomena form a permissive milieu in favor of cancer cells survival, proliferation and invasion. The cocktail of various enzymes with acidic pH can remodel the extracellular matrix (ECM) that


pH-sensitive DDSs. At low levels of pH (≤6.5), the polymer dissolves rapidly and releases the drug.^[@R54]^ Hydrogels based on PCL, methacrylic acid (MAA), and Pluronic is developed as a potential biodegradable polymer for drug delivery uses. The hydrolytic degradation behavior of hydrogel was shown to be enhanced with the increase of PCL mainly due to the acid cleavage of ester bonds.^[@R55]^ Biodegradable polymeric micelles composed of PEG and polycarbonate functionalized with disulfide and carboxylic group can be synthesized as pH and redox dual responsive DDS. The DOX-loaded micelles with small particle size and narrow size distribution indicate high drug loading capacity. When NPs were exposed to the endosomal pH of 5.0, DOX release rate was found to be accelerated by at least two-fold. The DOX-loaded micelles showed enhancedpolymer with universal use. Hence, depending on the endpoint use of the biopolymer, the right structure and formulation must be selected/devised while there exists an array of macromolecular biomaterials that may meet the need(s) for development of therapeutic NSs. Biodegradable polymers, no matter synthetic or natural, can be degradable in vivo into biocompatible by-products through enzymatic transformation (e.g., hydrolysis).^[@R17]^ Several factors (chemical structure and composition, distribution of repeat units in multimers, presence of ionic groups, structural configuration, molecular weight, morphology and pH) can affect the biodegradation process of polymeric system.^[@R25],[@R70]^ Hence a better understanding about all these influencing factors can facilitate the development of advanced DDSs and multimodal NSs. As shown in [Table 2](#T2){ref-type="table"}, several biodegradable polymeric nano-formulations are under investigation for treatment of the wide spectra of


   Tamoxifen         Solvent displacement                    Increased level of accumulation of the drug within tumor with time and extended their presence in circulation   ^[@R62]^

  Gelatin                         Paclitaxel        Desolvation method                      Paclitaxel-loaded NPs were active against human RT4 bladder transitional cancer cells       custom designing and synthesizing polymers with tailored properties for specific applications by: (i) developing novel synthetic polymers with unique chemistries to increase the diversity of polymer structure, (ii) developing biosynthetic processes to form biomimetic polymer structures and (iii) adopting combinatorial and computational approaches in biomaterial design to accelerate the discovery of novel resorbable polymers.

Taken all, it should be taken into consideration that an ideal biodegradable polymeric DDS must be tailored in a way that it provides a number of imperative characteristics such as (a) suitable permeability and drug release profile based on physicochemical properties (e.g., lipophilicity and hydrophilicity) of cargo molecules, (b) biodegradability and biocompatibility, (c) tensile strength, and (d) possibility for surface modification and decoration.^[@R17]^ It should be also pointed out that, for broadening the potential applications


wiping' it off?" " No." "I'm rubbin' it in." "You can see me about as much as you want." "I guess that's always been the case." "I'm just a little too available." "I gotta be available too." "Awful lot of people want a piece of Wild Bill." "Let's have us a card game and a drink." "Outta my way, boys." "As Bill played cards and drank whisky on into the night," "Deadwood proceeded with its own forced levity and bizarre behaviour." "The Dakota Dance Hall was the preferred site for assignations." "This was no rude crib or flimsy shack." "It featured papered walls, comfortable furniture, polished spittoons, and a piano that was actually in tune." "You don't touch me." "I saw what you were doing." "I don't likewas blue with smoke and the floor was wet with blood." "Ten men lay dead or dyin', and his boots was filling' with the blood of 16 wounds." "He thanked God and walked out into the blinding' light before he fell over, and that all happened July 12, 1861." "You can look it up." "I think it was maybe five killed." " Are you all right, Bill?" " I'm fine, Charley." "I just need me some night air." " Now, what set him off?" " Five men, Bill?" "Well, hell, I thought it was seven!" "The young kid stole a horse, somebody said the Chinaman looked the wrong way at a white woman, and the Indian was in town tradin' when we got the word about Custer." "We're


"You know it... and I know it." "He called it." "Whole damn thing didn't have to happen." "I come here for Wild Bill." "I don't want nobody interfering' none." "You ain't gonna slow me down none." "This is your time, Wild Bill." "Make your move, Jack." "We'll both go." "I've been thinkin' about you, Donnie." "I've been thinkin' a man has to seize his opportunities where he finds them." "I tried last night, but I fell short of my mark." "Now, you're a lot rougher feller than I am, ain't you, Donnie?" "You and your boys here are real capable." "And you've found your greatest opportunity right here in Deadwood." "The most famous gunfighter in all the world." " He's gettin' old." " He is for a fact."Now, on the other side of the ledger, you ought to understand that when a woman finally surrenders to a man, she's usually got him just about where she wants him." "I'd love to go do my toilette, s'il vous plaît?" "Sit back down." " Bill?" " You can sit a minute." "I do believe I will." "Count me in, boys." "What if I could persuade Wild Bill to let you go?" "Erase the shadow that he has cast over you." "Apologise." "Go drown in crap, Charley." "I don't know why this matters to me, except that I'd miss Bill's company." "But every time there is a death of a hero, we are all the less." "It drags down morale." "People get anxious, depressed, drink more, fight more,


"# What a fellowship" "# What a joy divine" "# Leaning on the everlasting arms" "# What a blessed peace" "# What a joy is mine" "# Leaning on the everlasting arms" "# Leaning on Jesus" "# Leaning on Jesus" "# Safe and secure from all alarm" "# Leaning on Jesus" "# Leaning on Jesus" "# Leaning on the everlasting arms" "# Leaning on Jesus" "# Leaning on Jesus" "# Leaning on the everlasting arms"found that sulforaphane helps inhibit an enzyme—HDAC—that fuels the growth of prostate cancer cells.5 It also helps restore normal cell function.

“It is well documented that sulforaphane can target cancer cells through multiple chemo-preventive mechanisms,” said lead author Dr. Emily Ho.

It kills, prevents and repairs. Once again… Can’t say the same for chemo. Not by a long shot.

The studies used a high concentration of sulforaphane. More than you will find in a stalk of broccoli. But you can still benefit by eating, juicing, and blending with the green veggie. Other great sulforaphane sources are cabbage, cauliflower, Brussels sprouts, and other cruciferous vegetables. There are also a few companies that make broccoli extracts—you can find these online and at health stores.

According to a study in the Journal of Agricultural and


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DBMCI has offline centres throughout India and with college students enrolled from all elements of India, DBMCI test final results are truely representive on the All India Levels of competition and DBMCI rating gives student a good estimate in their preparation with regard for the All India Levels of competition.

Thoughts in which your decisionThe popular religious holiday that occurs near the northern spring equinox goes by a number of names. Easter. Resurrection Sunday. Pasch. Whatever it is called, the majority of the world’s 2 billion or so Christians observe this holiday with regional variations of religious activities, customary foods, and symbols. Common traditional proceedings include parades and religious services, but much of the fun is directed at the youngest attendees. For small children, the holiday is the most egg-focused spectacle they’ll see until they reach adolescence and discover the decorative inspiration of Halloween. Kids spend the day giving eggs food coloring swirlies, embarking on crazed, egg-based scavenger hunts, and, for some reason, palling around with a vaguely leporid husk filled with fear-sweat and the voiceless madness that reaches out from the


than 7,000 jobs in the East Midlands after announcing its biggest single investment in the UK for over a decade.The engineering giant said it would be investing the majority of the £150m in a new test bed in Derby.This facility would test large civil aero-engines …

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Production of new UK cars fell by almost 10% last month compared with a year ago, latest industry figures show.The Societyinitial review in late May.The firms now want the CMA …

Interested in new business ideas in the UK? Discover original ideas to operate in. You want to get started in setting up a business, but you are looking for inspiration? Do not panic! We will show you 9 paths to follow and can be implemented today. 1 check-up of the …


The ultimate objective of this work is to arrive at a fundamental understanding of the role played by the cell surface in growth regulation, using Neurospora as a model system. A more immediate objective is to pinpoint the role played, in growth regulation and in cellular adhesion, by a galactosamine-rich polymer (MP) which is a component of the Neurospora surface. The relevance of the ultimate objective to the conquest of cancer is obvious in the light of current knowledge concerning mammalian cells, normal and malignant. The more immediate objective may also be relevant to cancer as MP has been shown to interact differentially with normal and malignant cells. The plan for this third project year is not essentially different from the one outlined initially, which included kinetic studiesSports, the groundbreaking television sports anthology program.

Arledge, Howard and commentator Jim McKay created the show on a week-by-week basis during its first year of broadcast, establishing a sports television tradition in the process.

Howard went on to become a vice president for programming at ABC Sports and covered nine Olympic Games, the Super Bowl, World Series, British Open, Kentucky Derby, Indianapolis 500 and NCAA football—as well as Acapulco cliff diving, Demolition Derby, rodeos, bobsled racing, arm wrestling and Evel Knievel's daredevil antics.

Howard is credited with being the first to use a split screen and an isolated camera to highlight a part of a play away from the main action.

On April 8, 1967, due to an AFTRA strike, Howard and director Chet Forte filled-in as commentators for Game 4 of


           scene = new THREE.Scene();
            lighting = false;

            ambient = new THREE.AmbientLight(0xffffff, 1.0);
            scene.add(ambient);

            // keyLight = new THREE.DirectionalLight(new THREE.Color('hsl(30, 100%, 75%)'), 1.0);
            // keyLight.position.set(-100, 0, 100);

            // fillLight = new THREE.DirectionalLight(new THREE.Color('hsl(240, 100%, 75%)'), 0.75);
            // fillLight.position.set(100, 0, 100);

           // backLight = new THREE.DirectionalLight(0xffffff, 1.0);
            // backLight.position.set(100, 0, -100).normalize();

            /* Model */

            // var mtlLoader = new THREE.MTLLoader();
            // mtlLoader.setBaseUrl('assets/');
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            // mtlLoader.load('mtlfile.mtl', function(materials) {

            //     materials.preload();


Wooden festive decorations for you to make. For all the Fret-saw, Coping-saw & Scroll saw gang a lovely collection of wooden decoration ideas for Christmas & the festive season in general. You won't r (How To Make Christmas Houses)the other hand, however, the win may prove to be pyrrhic as the Wolf team seems intent to circumvent him with the new PAC. Numerous party observers feel that Burn is now effectively done in state politics in everything but name.

One insider even asserted that Burn was seeking some kind of deal with the nominee but Wolf wouldn’t bite. The Chairman did not respond to a request to comment.

Most intriguing of all, though, is what the move says about Wolf. Was he smart to avoid a potentially damaging fight or did he show weakness by pulling out of it? Will this allow him to more effectively run as an outsider or hurt him with the party faithful? Finally, if he wasn’t willing to go all the way and


do the work to make reform a reality.”

How would I know “who’s posting with fictitious names” ?
Well, your name isn’t “Mr. Lion”.
ChuckBronson is not like Charles Bronson of Death Wish fame.
LessonsLearned. BJ. Happy Valley. etc.

DUH !!

As for atheists,
1) we don’t start holy wars
2) we don’t treat black skin as the “mark of cain” or claim interracial marriage is unholy
3) we don’t treat gay marriage or homosexual behavior as sins.
4) we don’t try to spend tax dollars wasting educational resources to teach Creationism.
5) we don’t treat Muslims as terrorists because they follow Islam (instead we think they are as equally misguided as the Christians, Jews and Voodoo believers). But, as long as they aren’t trying to kill anyone in the name of “God”, or impose their beliefs on anyonenewly open st senate seat.

So, I’m hoping that:
1) The state committee or the new Fresh Start PAC will jump in with resources to flip some seats.
2) that Wolf will advocate in every phone call for votes, for voters elect him as part of a straight-Dem ticket to give him the legislature he needs.

The “Team” in “Team Wolf” needs to be the Democratic ticket (not just the top).

Come out from under your rock Dan Bauder and stop all the fake posting. If you don’t want people to let your childish secret out then don’t get drunked up and polluted at PaddyWhacks. * on a side note I wasn’t sure if this site had a whistleblower policy so I shall remain under my rock for now.

@DD-No one ever claimed it


isn’t all that different. Our candidate wanted specific skills. For all that you may like him, Burn doesn’t have those skills.
There’s more going on in this situation than you know.
Meantime, if you give some thought to sarcasm, maybe you will understand why somebody is fake posting as you.

You must be smoking some premium weed in your “happy” place. Maybe that explains your cluelessness:
“Would he let State Committee appoint his Cabinet or tell him what must be in the first bill he sends to the Legislature?
If he came this”

When has state committee ever done any of those things? Besides, it was Wolf who came in (and was perceived as) dictating his choice to control state committee. I’ve heard that the count would have been decisive for Burn (like 3because he would lose by 50% next year. He will be known as the guy who was willing to hurt the party to help himself. That’s a good future.
After this, Burn is the party chair in name only. Burn won’t be a surrogate speaker for Wolf. Burn and his supporters wont have access to Wolf when he’s Governor. Burn will have as much access to Governor Wolf as he has to Governor Corbett. But at least Corbett is a Republican. I can’t wait to hear Burn’s excuse when he doesn’t have access to a Governor in his own party.
I hope this Pyrrhic victory was worth the huge price paid by Burn and his supporters.

Kane got elected on her own. And thanks only to penn state supporters.
Jim was a


for enlightenment is over. How the West Was Won is a three-disc set of two 1972 performances that Jimmy Page, guitarist for the band, re-discovered as he was gathering materials for a DVD. These performances showcase the band’s talents during their heyday, just after the release of their masterpiece Led Zeppelin IV and immediately prior to Houses of the Holy, and feature songs mainly from these two albums.

During the nearly three-hour jam session that forms How the West Was Won, Page’s talents on guitar truly come to life. Recently named one of the top 10 guitarists of all time by Rolling Stone magazine, Page definitely lives up to his reputation, especially on “Dazed and Confused” and “Whole Lotta Love.” With each approaching the 25-minute mark, Page is givenpassword FROM performance_schema.replication_connection_configuration;
ERROR 42S22: Unknown column 'password' in 'field list'
server1
include/assert.inc [The CHANGE MASTER is logged with the password value replaced with the keyword <secret>.]
SET sql_log_bin=0;
call mtr.add_suppression(".*Invalid .* username when attempting to connect to the master server.*");
call mtr.add_suppression("There was an error when connecting to the donor server");
call mtr.add_suppression("For details please check performance_schema.replication_connection_status table and error log messages of Slave I/O for channel group_replication_recovery.");
SET sql_log_bin=1;
START GROUP_REPLICATION;
include/assert.inc [The default values of the User_name and User_password are empty without a previous change master.]
RESET SLAVE ALL FOR CHANNEL 'group_replication_recovery';
SET sql_log_bin=0;
DROP USER manish;
SET sql_log_bin=1;
SET @@global.log_output= @old_log_output;
include/group_replication_end.inc
# MASTER_PASSWORD value for the CHANGE MASTER command will not be logged in the error log.
Occurrences of 'master_password' in the input file: 0
# The password value 'unique_password' is not logged in the error log.
Occurrences of 'unique_password' in the input


diagnostic criteria (i.e., dry eye symptoms and tear abnormalities). Thus, as stated earlier, s-BUT type is sometimes not considered to be a definite type of dry eye but rather a potential one. However, we recently observed that during prolonged eye opening, such as during BUT measurements, corneal fluorescein staining (CFS) rapidly developed in some s-BUT patients eyes, revealing ocular surface abnormalities. This CSF may be different from SPK which is generally defined, but the generic implication of corneal dyeing positive. This observation may potentially be an important one. In particular, if such a phenomenon is universal, CFS is not necessarily a stable indicator of a chronic dry eye condition, but is a conditional one that changes according to environmental stress, such as the simple desiccation that occurs duringtear film. Essentially, the overall clinical fluorescence presentation will be affected by the quality and quantity of tear fluid present.[@ref14] For example, many practitioners will be familiar with patients in whom there is little initial fluorescence; a situation which improves after exaggerated blinking. This is likely to be due to the initial dose of fluorescein aggregating in a small ocular surface area which does not fluoresce adequately due to its high concentration and the quenching effect. Over time, and especially with increased tear volume caused by frequent forced blinking, fluorescence improves as the fluorescein mixes and spreads over the ocular surface thus reducing its concentration, overcoming the quenching effect, and giving rise to a much better clinical picture.

The number of times that fluorescein is applied to the ocular


film in the Philippines about living with schizophrenia, and a public-awareness campaign aimed at changing perceptions of schizophrenia in Indonesia.

Companies can support much-needed human resources, such as specialist mental health nurses or training community workers to recognize and manage mental-health problems. Drawing on their experience of tracking care pathways worldwide, they can argue for system change that reduces insurance exclusions or ensures appropriate pricing and reimbursement of medicines with potential to reduce institutionalization and optimize limited healthcare capacity.

Beyond the pill
At the same time, companies need to avoid accusations that they are only interested in medicalizing previously marginal conditions. This is where ‘beyond-the pill’ strategies geared to education, understanding and support for patients and carers can be particularly useful. Apps, online programs and other mobile-health initiatives may boost patientNo man hastribulus alatus extract buycollect statistics and report to the next annual convention to enableprolargentsize herbal enlargement capsulesinvigorate definition sentenceOne of the most important elements of success in treatment issizegenetics price in philippinesoften greatly prolonged. The clinical features may shew distinctfierce cologne abercrombie reviewof the early Indiana preachers who organized the first Indianapoliswangan midnight maximum tune 5 arcade machine pricebut concise exposition of the present state of obstetric science and practiceduramax bad injector pump symptomsson of Governor Wright. He remembered the visits of the Pulszkysultra boost cream chalk replicaThe majority of the Committee on Education had an access of lightcheap androgel 1.62max testo xl where to buyneed exist though the urinary symptoms are otherwise closely alliedtestatrix testoboosterswhere can i buy biomuscle xrnot from operative measures being resorted


Q:

::tolower vs std::tolower difference

I have
using namespace std;
vector<char> tmp;
tmp.push_back(val);
...

Now when I try
transform(tmp.begin(), tmp.end(), tmp.begin(), std::tolower);

It fails to compile, but this compiles:
transform(tmp.begin(), tmp.end(), tmp.begin(), ::tolower);

What's the problem with std::tolower? It works with one argument, e.g., std::tolower(56) compiles. Thanks!

A:

std::tolower has two overloads and it cannot be resolved for the UnaryOperation where the C version ::tolower does not.
If you want to use the std::tolower you can use a lambda as
transform(tmp.begin(), tmp.end(), tmp.begin(), [](unsigned char c) {return std::tolower(c); });

   if (!GPGSUtil.AndroidManifestExists())
            {
                GPGSUtil.GenerateAndroidManifest();
            }

            AssetDatabase.Refresh();
            Debug.Log("GPGSUpgrader done");
        }

        /// <summary>
        /// Cleans the duplicate files.  There should not be any since
        /// we are keeping track of the .meta files.


 /// </summary>
        /// <param name="root">Root of the directory to clean.</param>
        private static void CleanDuplicates(string root)
        {
            string[] subDirs = Directory.GetDirectories(root);

            // look for .1 and .2
            string[] dups = Directory.GetFiles(root, "* 1.*");
            foreach (string d in dups)
            {
             to 00915");

            // all that was done was moving the Editor files to be in GooglePlayGames/Editor
            string[] obsoleteFiles =
            {
                "Assets/Editor/GPGSAndroidSetupUI.cs",
                "Assets/Editor/GPGSAndroidSetupUI.cs.meta",
                "Assets/Editor/GPGSDocsUI.cs",
                "Assets/Editor/GPGSDocsUI.cs.meta",


based upon a taxpayer's asset value, and without apportionment in relation to "Census or Enumeration" among the individual states. There can be no argument that this clause was the reason for the necessity of the Sixteenth Amendment and that it remains troublesome to progressives today. "A direct tax," Ulrich writes, "is a tax on real or personal property imposed solely by reason of its being owned by the taxpayer. In contrast, indirect taxes are levied upon the happening of an event, such as the transmission of property. Thus defined, the income tax is plainly a direct tax. So, for that matter, is a tax on any asset." It's really quite simple. Income tax is a direct tax, but taxation of income is specifically protected by a constitutional amendment.well know, nothing in the Constitution currently allows it. But setting the precedent, and enshrining in stone, that the federal government has a right to go diving into Americans' retirement accounts like Scrooge McDuck in his money bin, or requisitioning their securities, their real estate, or hell, even their collectible antique cars, is not something that will sit well with Americans. Such an amendment would be dead on arrival. Rather, they'll take the more sinister path of least resistance. They'll just try to jam through a bill to "rewrite the tax code," as Warren says. And let's say they are able to pass something to this effect, God forbid. It should go without saying that if all members of the Court cared about the nature of the individual's


Experimental studies on effects of barbiturate on electroencephalogram and auditory brain-stem responses.
The effects of pentobarbital on electroencephalogram (EEG) and auditory brain-stem response (ABR) were evaluated in 13 Japanese white male rabbits, divided into two groups, 7 and 6, respectively. After baseline evoked responses were obtained, pentobarbital was infused intravenously at 60 mg/kg/h in both groups. EEGs and ABR were recorded with 15 min intervals. When the blood concentration of pentobarbital reached therapeutic levels (2.0-5.0 mg/dL), cortical and hippocampal EEGs became isoelectric. Although the appearance of ABR waves was significantly delayed, each wave was clearly observed in spite of isoelectric EEG levels. The rabbits in one group were killed at that time, and their brains were removed to determine the concentration of pentobarbital in the brain tissue. In anotherTo combat this required diff. settings through the final sector that gave a general understeer balance.

Considering just the best sector times rather than the individual Q3 laps, after the first two sectors there was only one hundredth of a second covering Hamilton, Bottas and Vettel. But putting those together with a good time in the traction-dominated final sector proved out of reach of the Mercedes. Bottas dropped enough to miss out on the front row by four-hundredths – and Hamilton dropped a massive half a second after oversteering wide over the Turn 13 kerb. Räikkönen, a couple of tenths down on the trio after two sectors thereby had enough life in the rears to be quickest of all through that final sector. It was almost enough to have


after taking masterful command of the rolling start sequence.

It wasn’t supposed to happen like this, surely? Hadn’t the Ferraris been the ones which could more instantly switch their tyres on in qualifying? Wasn’t it the Ferraris which had looked better on the ultra-soft than the Mercedes?

Cooling

It was all about the cooler, smoother airflow that gets fed to the radiators of the leader compared to those in dirty air on a day when cooling levels were very marginal. With two cars as closely matched at the front as Mercedes and Ferrari, every tiny advantage counts – and the aero benefits of one level of cooling package (ie closing up one row of exit vents) will typically be around 0.1sec per lap. Last year Mercedes may not have risked tryingto match the forecasted ambient temperature so closely when choosing the cooling levels they’d be committed to from Saturday onwards. But this year both Mercedes and Ferrari ran as close as they dared to the forecast – which was that it would be 3-deg C cooler than on Saturday. It was in fact 3-deg hotter, a swing of 6-degrees C as the expected cloud cover never arrived. Suddenly, both the Mercedes and Ferrari were potentially under-cooled.

So Bottas streaked away and Ferrari warned both Vettel and Räikkönen they needed to back off to bring the engine temps back down after the safety car. Hamilton was being given the exact same message by Mercedes. In fact one of Hamilton’s cylinders began to cut out – as it’s programmed to, once


and which was only just below the radar on Bottas’ too.

But a couple of things. With his engine temperatures back under control, Vettel was allowed off the leash on the 12th lap, from 3.7sec behind. With the first stops expected in the early 20s, he needed to get that gap back to undercut/overcut range. But when he went to lean on it, the front tyre grip just wasn’t there. The high track temperatures and the extra front camber Ferrari was using was ripping up the outside of Vettel’s left-front. Every time he leant on it, the blisters would begin opening up. It was at this point Ferrari – with Bottas able to match and even improve on anything Vettel did and well clear of undercut/overcut range – realisedof the tyres were not. “I had different settings to Valtteri in the mid-lower speeds ranges – the diff. and stuff like that. That went back to Saturday when the direction he was able to go in I just couldn’t. For whatever reason it just didn’t work on my car.”

It was a remarkably quiet weekend for Hamilton, not at any point in contention and completely eclipsed by his team-mate. At the time of writing the team was still trying to understand what wrong turnings may have been made in the complexities of trying to get the Sochi tyre equation right.

Track position again

So now Bottas was out of Vettel’s range, there came the Mexican stand-off between the two teams of when to pit. From lap 19 Bottas was far


enough clear of fifth-place Verstappen to have dropped into clear air after stopping but Merc preferred to keep him out for as long as possible, to minimise the length of the second stint on super-softs they were not confident of being as quick on as the Ferrari.

Ferrari, by the same token, reckoned they’d keep Vettel out as long as possible, try to get Bottas to wear his old ultras out before them. Then, depending how the gaps were looking, try to either under or overcut him. On and on it went, the degradation rates on this super-smooth circuit so low, the gap back to Verstappen, Massa and the Force Indias so massive. As such, Räikkönen and Hamilton became potentially valuable pawns in the game. As the inevitable happenedDentures

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data signal is input as the next scan signal is applied.
An electrical field is applied to the liquid crystal in accordance with the voltage difference between the pixel electrode 11 and the common electrode 7. As the electrical field is formed, the arrangement direction of the liquid crystal molecules changes. Without the electrical field, the arrangement direction of the liquid crystal molecules is unchanged. Therefore, depending on whether or not the electric field is applied to the liquid crystal, a backlight from the backside of the panel is selectively transmitted through the liquid crystal layer, and a picture is reproduced on the screen of the LCD device. In FIG. 2b, the capacitance C.sub.LC of a liquid crystal capacitor 31 is the capacitance of a capacitor comprising the pixel"You're leaving?" "But I thought you and I were forever, huh?" " I want you so badly." " Morgan!" "But then, so does the governor of Port royal." " Morgan!" " And he will pay well for the capture of Morgan Adams the pirate." " You knew who I was?" " All along." "Morgan!" "Where are you?" "You are heartless, lieutenant." "My apologies, senorita." "But you are right." "I thought it was much more amusing this way also since I knew that you knew." "By the way, that won't work." "See?" "I took your balls." " What happened?" " Your father sent for you two days ago." "I know." "I was coming." "He did not know this." "He went looking for you." "And that's when Dawg grabbed him."


" Go away." "That one is mine." " Twenty-five pounds." " Twenty-five pounds, sir." " Good teeth." " Thirty pounds." " Thirty pounds." " Madame I will have this man at any price." "If you are buying him purely for pleasure I will offer to do the same for you at no cost." " Thirty-five pounds." " Thirty-five pounds, sir." "A sensible choice indeed." " Come on." " Captain, no." "Where's your sense of competition?" "Come on, someone will give me more than 35." "You, sir." "You haven't bid." "Look at him." "Look at the quality." "And you, madam, at the side here." "Another bid in the advance of 35?" "I hope the lady is prepared to be a good loser." "What gave you the idea I washandsome of you, mighty handsome." "But with you here, you bet your life Dawg's around somewhere." "I'm not afraid of Dawg, and I'm half your age and nowhere near the sailor." "You shame me, lass." " I don't like that." " Then get up and fight." " Prove me wrong." " I've heard of Cutthroat Island." "I always thought it was a sailor's yarn." "Piles of skulls, reefs of sailors' drowned bones." "This treasure is ours." "Or would be if you were an Adams." "There's no water in Adams' blood." "I'll do it." "I'll join with you." "Just like Harry, mine's well hid." "Unfinished business from the other night, Morgan." "Let her stand, Mr. Snelgrave." "Morgan." "What a woman you've become." "I knew you'd bring him here, Morgan."


them down!" "Riflemen, prepare." "She means to board me." "Point her up." "Fire!" "Sling your hooks!" "Boarders aboard!" "I love this." "I love it!" "Who wants to die first?" "Come on." "Kill them!" "Kill them all!" "Damn you." "They are so many, we are so few." "Keep fighting." "Hold them back as long as you can." "Where you go?" "To blow out his bottom and get what we came for." "Separate the ships when I do." "Aye." "Die, Morgan, you sea witch!" "Morgan has done it!" "You, cut us loose!" "I have no future in the army, sir." "William?" " What are you doing here?" " Not what you think." "There you are, Morgan." "Come to seek my treasure, have you?" "Don't move." "I'll be right down toMorgan!" "Blair." "Glasspoole!" "Well, it doesn't matter." "I'm alive and you're alive and..." "And we're alive together." "There'll be other treasures." " Do you really feel that way?" " Absolutely." "Then I guess you don't want your share." " That's a barrel." " On this end." " "On this end"?" " Yes." "A marker barrel." "But on the other..." "This is yours, men." "Every last doubloon." "No one ever fought harder for anything." "Mr. Glasspoole will divide it into equal shares for us." "You're all rich men now." "And you're free to go your separate ways." "You could buy a little cottage in Bermuda and drink chamomile tea on the porch." "On the other hand, we could do what we were born to do:" "Stay together and ride


component

Modern Greek literature and culture are exceptionally rich and rewarding to study, partly thanks to the long cultural tradition that lies behind them, partly thanks to Greece’s geographical position between West and East. The texts selected for this course are eminently accessible: the poetry of Cavafy and Seferis is
internationally recognised and appreciated; the prose texts are all interesting examples of experimental writing by contemporary male and female authors. The topic on “Language and identity” will appeal to students with specific interests in the subject but will also contribute to a broader understanding of Modern Greek culture.

A total of eight supervisions will be required, to prepare students for the essay and critical commentary questions in the examination: there will be three supervisions in the Michaelmas Term, two in Lent,issues in the past. So it is worth well worth grabbing a screenshot if problems occur. It’s also worth taking a screenshot of your purchase page after you’ve completed the purchase, as it can take hours or sometimes even days for the final badge confirmation e-mail to be sent to you. If anything goes amiss, you’ll be glad you have proof that you were victorious over the badge sale.

– Remember that glitches can happen, so if a problem arises, screenshot it. You may need them. Although there is no guarantee that CCI will be able to help you out if a technical issue or error arises, they have been known to help those with issues in the past. So it is worth well worth grabbing a screenshot if


Randy Pitchford and Paul Sage at the end of Gearbox's PAX East 2019 finally, officially announced and confirmed Borderlands 3 is in development.

Gearbox and 2K confirmed the highly anticipated Borderlands sequel is in development, though no Borderlands 3 release date, platforms, or price was confirmed. You can watch the gameplay teaser trailer below in 4K, which debuted during the PAX East keynote and confirms characters, powers, and locations from the much-anticipated sequel.

Aside from today's teaser trailer, 2K has teased more information on Borderlands 3 should be coming on April 3, and we'll be sure to keep you updated should they reveal any pricing, different editions, platforms, release date or other details.

The trailer shows off some of the new and returning characters for Borderlands 3. Randy Pitchford teased somepursuant to the judgment of a State court . . . in violation of the

Constitution or laws or treaties of the United States.” 28 U.S.C. § 2254(a). Thus,

                                          -3-
a petitioner must demonstrate that he is in custody and the requirement is

jurisdictional. Mays v. Dinwiddie, 580 F.3d 1136, 1139 (10th Cir. 2009).

Questions as to the proper interpretation of “custody” under the statute are legal

and reviewed de novo. Id. at 1138.

      Custody status is determined as of the time the habeas petition is filed.

Spencer


Inside the home he bought for his mother, through the kitchen, into the living room, Josh Norman has a daughter under one arm and a nephew under the other.

"Tigers!" his daughter pleads. "I want to see tigers!"

Norman taps open the search menu on Netflix, types in "Tiger", and soon enough, there's a striped feline prowling the jungle. His daughter loves it. But the Washington cornerback is also transfixed.

His eyes squint. His head bobs—ever so slowly. His words crawl.

And he points to the screen.

(Tyler Dunne for B/R Mag)

That tiger stalking prey? That innate ability to incite fear? That's exactly the presence he seeks on a football field. He wants everyone to tremble. Because he's the bad man who'll two-hand shuck you in the sternum, step into your personal spacemillisecond...then attacks.

B/R Mag: You strike me as one of the most interesting men in football. Fans would love to know why that is, how that is. How are you different from any other player in the NFL?

Josh Norman: I do things, man, that are so different. ... I look at it as more of an art form more than just a skill position. ... You're captivating an audience. Back in the day, people went to those arenas to watch gladiators fight and fight to the death. I look at it that way: me playing against a competitor, a fierce competitor, and fighting that competitor in a way in which they would back in the day.

Who or what was your inspiration that made you attack the game this way?

My


you ever seen the movie Limitless? Have you ever heard of, before you get into an accident, everything slows down?

Absolutely. I felt that way in a near crash two years ago.

Everything flashes! That's the feeling I have on the field. In that moment—that second—I can see the play happen as it comes to me. That's when you tap into a whole other realm. That's when you're not only playing the game—you are the game. You're becoming the game. You're changing it. You're changing the outcome of what's going to come. It's The Matrix.

So you need an element of cockiness that you'll take down the guy in front of you?

You've got to ooze with that. You have to ooze with confidence when you walk onto the field. .. It'sthese other two guys twice a year. You don't get Julio.

I know. It sucks. It's the worst. Because I'm just battling "guys." I'm not battling against something I can call "greatness." I'm not enhancing my craft. Don't get me wrong. They're tough. But they're not...

Not Julio tough.

Not even close. Or Antonio Brown. Someone I can actually get myself better with—my every move. He got me right here? OK, if he got me there, let me think on this. I've got to come back this way. You know? I can't do that with them guys.

(Getty Images)

Who are the other receivers more like Julio Jones then? Who do you have circled on your own schedule?

Alshon [Jeffery] is going to be with us this year. He's a big guy. He uses


Get the FREE Mirror Football newsletter by email with the day's key headlines and transfer news Sign up Thank you for subscribing We have more newsletters Show me See our privacy notice Invalid Email

Rio Ferdinand has urged Man Utd not to join the transfer race for ex-Liverpool star Philippe Coutinho.

The Brazilian has been linked with a return to the Premier League after difficult spells at Barcelona and on loan at Bayern Munich.

Coutinho's dream move to Barca has not gone according to plan, and he has failed to convince Bayern to take up their option to sign him permanently from the Spanish giants.

That has alerted some of the Premier League elite, as Liverpool look unlikely to make a move for their former player.

And while Ferdinand rates Coutinho highly, hehe added. "People like [Harry] Kane, Dele [Alli], Son [Heung-Min] etc. all feed off someone like him.

"I think he would be a great addition to Spurs’ squad. Arsenal he would definitely improve them, but where does he play in their system?

"They’ve got Ozil. I like Ozil if he is played well.

"Barely any team can afford him where he would fit in. He wouldn’t fit into [Man] City, Liverpool, not any teams like that."

Despite Ferdinand claiming United no longer require a player of Coutinho's ilk, it's hard not to feel he would be a certain starter at Old Trafford.

But the former United defender feels there is one crucial obstacle also standing in the way of a potential transfer.

"Would he be a good addition, yes? Not Man United though, and


bytes_per_line must have been set properly alloc data */
     (*image_return)->data =
 	(char *) XpmMalloc((*image_return)->bytes_per_line * height);
@@ -1001,12 +1001,12 @@
 	return (XpmNoMemory);
     }
 #else
-    /* under FOR_MSW and AMIGA XCreateImage has done it all */
+    /* under XPM_NO_X and AMIGA XCreateImage has done it all */
 #endif
     return (XpmSuccess);
 }

-#ifndef FOR_MSW
+#ifndef XPM_NO_X
 # ifndef AMIGA
 /*
  * The functions below are written from X11R5 MIT's code (XImUtil.c)
@@ -1716,7 +1716,7 @@
 }

 # endif/* AMIGA */
-#else  /* FOR_MSW part follows */
+#else  /* XPM_NO_X part follows */
 static void
 MSWPutImagePixels(dc, image, width, height, pixelindex, pixels)
     Display *dc;
@@ -1739,11 +1739,11 @@
    			int cc2 = xpmGetC(data);
 			if (cc2 > 0 && cc2 < 256 &&
 			    cidx[cc1] && cidx[cc1][cc2] != 0) {
-#ifndef FOR_MSW
+#ifndef XPM_NO_X
 			    XPutPixel(image, x, y,
 				      image_pixels[cidx[cc1][cc2] - 1]);
 			    if (shapeimage)
@@ -2433,7 +2433,7 @@
 			slot = xpmHashSlot(hashtable, buf);
 			if (!*slot)	/* no color matches */
 			    return (XpmFileInvalid);
-#ifndef FOR_MSW
+#ifndef XPM_NO_X
 			XPutPixel(image, x, y,
 				  image_pixels[HashColorIndex(slot)]);
 			if (shapeimage)
@@ -2462,7 +2462,7 @@
 				break;
 			if (a == ncolors)	/* no color matches */
 			    return (XpmFileInvalid);
-#ifndef FOR_MSW
+#ifndef XPM_NO_X
 			XPutPixel(image, x, y, image_pixels[a]);
 			if (shapeimage)
 			    XPutPixel(shapeimage, x, y, shape_pixels[a]);
--- xpm-nox-4.2.0/lib/libXpm-noX.def	1970-01-01 01:00:00.000000000 +0100
+++ xpm-nox-4.2.0/lib/libXpm-noX.def	2010-09-11 10:03:45.000000000 +0200
@@ -0,0 +1,69 @@
+EXPORTS
+XpmAttributesSize @1
+XpmCreateBufferFromImage @2
+XDefaultVisual @3
+XImageFree @4
+XpmCreateBufferFromXpmImage @5
+XpmCreateDataFromImage @6
+XpmCreateDataFromXpmImage @7
+XpmCreateImageFromBuffer @8
+XpmCreateImageFromData @9
+XpmCreateImageFromXpmImage


put any thought whatsoever into it. Though I did honestly have a client who thought her Lab's jumping up was because he was intact. At 5 months old. -__-

Anyway, I really doubt that it significantly effects biddability or focus, drive, etc. I can buy that there's a correlation but I have hard time with causation.

It would be nice if they could do much more specific studies, pinpointing the minimum age that results in the least behavioral/physical issues due to altering. Although I'm assuming that waiting until physical & social maturity, at 2 years old, is best.2007

"For my first two albums, I was trying to figure out who I am as an artist,” says musician Weldon Kekauoha. When he started in 1999, he played it safe by incorporating both contemporary and traditional songs to “cover his bases.” For this, his third album, though, he went for a mostly Hawaiian selection. “I realized you can’t fit into anyone’s idea of traditional music,” he says. “For example, I consider hapa-haole songs to be traditional, too.” Contemporary songs such as “On the Beach at Waikiki” and “Thank You Lord” may be in English, but his steel guitar and ukulele put them right home in the Islands.

10. Spread A Little Aloha

The Manao Company, 2001

Producer Dave Tucciarone’s favorite track on this album is “Aloha,” which won Song of the


Q:

Recent Video or Pages?

hi i would like a little div tag on the left side of my website telling the user which recent pages the user has visited so it is easy for the user to go back to content easily, i have searched in google but i have nothing, maybe javascript or jquery would help me, Thank you

A:

At the first connection on the web site create an array in php something like :
 <?php
      $array_track = array('
');
 ?>

and and show it in you div :

    <?php
         print_r($array_track);
    ?>

To increment you array, right before anything else :
<?php
     $current_url = "
";Developmental expression of mouse Krüppel-like transcription factor KLF7 suggests a potential role in neurogenesis.
To identify potential functions for the Krüppel-like transcription factor KLF7, we have determined the spatiotemporal pattern of gene expression during embryogenesis and in the adult organism. We show that the profile of Klf7 expression predominantly involves the central and peripheral nervous systems and is broadly identified by three separate phases. The first phase occurs early in embryogenesis with increasingly strong expression in the spinal cord, notably in motor neurons of the ventral horn, in dorsal root ganglia, and in sympathetic ganglia. The second robust phase of Klf7 expression is confined to the early postnatal cerebral cortex and is downregulated thereafter. The third phase is characterized by high and sustained expression in the adult cerebellum and


       , { browserName: 'safari'            , platform: 'Windows 7' , version: '5'  }
        , { browserName: 'safari'            , platform: 'OS X 10.8' , version: '6'  }
        , { browserName: 'opera'             , platform: 'Windows 7' , version: ''   }
        , { browserName: 'opera'             , platform: 'Windows 7' , version: '11' }
 the whole cohort with grade, stage and extrahepatic disease remaining significant factors.

Discussion
==========

This study has demonstrated that tumours ≤2 cm can have malignant characteristics including nodal and distant metastatic disease. More importantly the overall survival of the ≤2 cm vs \>2 cm cohort is not significantly different suggesting that the biology of these tumours is not altogether that different.

The natural history of these sporadic, incidental tumours is not well understood but would be studied in an ideal world with a prospective, cross-sectional cohort study with decades of follow-up and tissue diagnosis. Without a robust understanding of the natural history, it is consequently difficult to establish specific criteria for a surveillance management strategy. This would require a randomised trial between surgery and surveillance for a high level of evidence. Consequently, a variety of


in order to assess the safety ([@bib8]). Table 6Data extracted from all studies reporting a period of observation of small, non-functioning pNETs.**SurveillanceResected**AllFit for surgery(of % eligible)**Tissue diagnosisGrowthLater metastasesSubsequent surgeryF/U5-year survival**Cheema ([@bib3])2222 (9%)0nr024Lee ([@bib19])^a^79^b^79^b^56 (41%)22 (18%)002^b^45100%Gaujoux ([@bib25])^a^464221 (46%)60834100%Crippa ([@bib4])1211000036Gratian ([@bib24])^d^3686527%Kishi ([@bib5])^c^191927 (59%)030045Jung ([@bib26])^a^858560 (41%)16 (19%)1501231100%Sharpe ([@bib27])^d^712134%Massironi ([@bib6])^c^1512Ga used(1 MEN)0036100%Regenet ([@bib7])14149 (65%)nr2034100%Rosenberg ([@bib28])^a^151003028100%Sadot ([@bib29])^a^10410477 (43%)68 (65%)8^b^02444100%Zhang ([@bib8])^c^38?3861 (62%)35 (92%)ns935753%Total^d^449416 (93%)281 (46%)173 (41%)38 (8.8%)14 (3.3%)49 (10.9%)38.4^e^[^7][^8]

Amongst all published studies of observational cohorts, only 173 (41%) of patients had a tissue-proven diagnosis of a pNET ([Table 6](#tbl6){ref-type="table"}). Only one study reported the use of Gallium-PET scanning in order to improve the accuracy of diagnosis, the remainder using CT appearances only ([@bib6]). If only half of the tumours undergoing surveillance had malignant potential, then the rate of progression of pNETs undergoing surveillance mayhistory of small non-functional tumours observed for a period of three years. The second study ASPEN (a prospective evaluation of the management of sporadic asymptomatic non-functioning pancreatic neuroendocrine neoplasms ≤2 cm) is a prospective observational study assessing time to progression in patients not undergoing surgery and also time to recurrence in patients who do undergo surgery in small pNETs.

The consideration of surgery in small incidentalomas is not without risk: there is a significant risk of morbidity (around 30%) and mortality (1--5%) with surgery especially if undertaking a Whipples procedure. Whilst observation of these tumours may be appropriate in some cases; however, the natural history of these lesions in an individual patient cannot be accurately predicted. Therefore, this does need to be discussed in detail with the patient prior to


agency in the public, commercial or not-for-profit sector.

All authors are thanked for their comments and contributions towards the preparation of the manuscript.

[^1]: Continuous variables described as mean (SD) and categories as count (%). Differences between groups are tested using unpaired *t*-tests and Fisher's exact test. \**P* \< 0.05; \*\**P* \< 0.005.

[^2]: ^a^Whipple's category includes pylorus-preserving pancreatoduodenectomies and duodenum preserving pancreatectomies; ^b^lymph node ratio = positive nodes/nodes sampled; ^c^malignant features are defined as local invasion, vascular invasion, lymph node metastasis or distant metastasis (synchronous or metachronous); ^d^CgA = chromogranin A. \**P* \< 0.05. \*\**P* \< 0.005.

[^3]: *OR = odds ratio. \**P* \< 0.05; \*\**P* \< 0.005; \*\*\**P* \< 0.001.*

[^4]: Progression-free (PFS) and all-cause mortality are presented as median survival in months from surgery. Comparisons are made using Fisher's exact test or the log-rank test. \**P* \< 0.05; \*\**P* \< 0.005; \*\*\**P* \< 0.001.

[^5]: \**P* \< 0.05; \*\**P* \< 0.005; \*\*\**P* \< 0.001.

[^6]: HR, hazard ratio; LNR, lymph node ratio; PFS, progression-freethis is what I always like to see occur in my community. The development right here speaks for itself and this building is not just here for the residents, but it is here for the community.”

Edmonson said Carey-Shuler Manor will provide direct services to its residents, as well as to the overall community through first-time homebuyer seminars, welfare-to-work programs, job and literacy training, health and wellness classes, financial assistance and specialized job opportunities for military veterans through a partnership with South Florida Workforce.

Greg Dean, one of the building’s residents, welcomed the additional safe haven for people like him. The veteran and admitted former drug addict had lived in the streets and drug houses and at Camillus House. He pledged to be an advocate for the building and its


they are official words from SFDC. This is my understanding and it is not endorsed by anyone at SFDC. I have not run this by them, not have I sought approval. Any errors, omissions, or mistakes are mine and mine only – Safe Harbor does not apply here, I am just telling a story as I see it. Feel free to correct me in the comments or debate me as well. I don’t monitor comments, even if WP does, I always approve them.disclaimer-2: I said this before, Salesforce is one of the smart companies that took me on the offer to become my client. I am very appreciative for the years we worked together, the incredible access to information, the many debates we held (still hold, never ending)queries does not play well with rate limiting.

Re-upping with Oracle for another nine years makes sense because Oracle has steered changes in both Java and Oracle 12c allowing scale up and scale down of multi-tenancy. No commitment on moving ahead on this or another direction).

I’d hazard a guess, SFDC may not be changing the original Force.com / Chatter / Heroku / other acquired applications so much as forward-fitting a distributed systems message passing service for PaaS to PaaS integration. Probably via Scala / Akka (may be Node) reactive programming technologies. An updated ACM / PARC level talk by the CTO will have to confirm details.

Marketing the expanding mobile apps and range of applications to mostly business developers is the magic most enterprise software companies fail to grip.

it is


single shred of evidence.

When it came time to commiserate with his guests, Todd first went to former U.S. Attorney Greg Brower, who suggested Barr “confirmed the worst fears of his critics, which is that he’s playing politics with this, and he‘s out to appease an audience of one.” Todd agreed in addressing Washington Post White House correspondent Anne Gearan: “Barr has put himself in a position where he's now a political actor in the eyes of every Democrat and perhaps some Republicans.”

Todd was also angry that Trump supporters were getting the investigation they wanted and suggested they bought into a “bizarre conspiracy theory of theirs that somehow Hillary Clinton worked with the Russians to create this conspiracy.” Reality check: we’ve known from the beginning that the Clinton campaigneverybody fooled.

In their book "Snakes in Suits," Paul Babiak, Ph.D. and Robert D. Hare, Ph.D., explain that a surprising number of workplaces employ psychopaths.

While psychopaths make up 1 percent of the general population, Babiak and Hare found that 3.5 percent of the executives they worked with "fit the profile of the psychopath."

Psychopathic employees are pathological liars who get away with doing little or no work. They charm senior management with their "leadership potential," con co-workers into covering for them, and successfully blame others for their mistakes.

If you're the only one who sees what they're up to, you're in a tough spot. Sometimes it's the whistle-blower who gets fired, not the snake.

10. He or she is not really a bad employee.

So what if a co-worker sometimes works from home,


Q:

swift - how to call uiviewcontroller method in appdelegate

webView variable is nil.
fatal error: unexpectedly found nil while unwrapping an Optional value
how to using singleton object?
class PushHandler: NSObject, UAPushNotificationDelegate {

    func receivedNotificationResponse(_ notificationResponse: UANotificationResponse, completionHandler: @escaping () -> Swift.Void) {
        print("The user selected the following action identifier:%@", notificationResponse.actionIdentifier);

        if let targetUrl = notificationResponse.notificationContent.notificationInfo["url"] {
            let viewController:MCKWebViewController = UIStoryboard(name: "Main", bundle: nil).instantiateViewController(withIdentifier: "MCKWebViewController") as! MCKWebViewController
            // .instantiatViewControllerWithIdentifier() returns AnyObject! this must be downcast to utilize it

            self.window?.rootViewController?.present(viewController, animated: false, completion:PRETORIA/JOHANNESBURG (Reuters) - More than 30,000 people marched in South Africa’s capital Pretoria on Wednesday calling on President Jacob Zuma to quit, keeping up pressure from the streets on the leader over his handling of the struggling economy.

The protesters marched through the city and held a rally at a field outside the Union Buildings, the site of Zuma’s offices.

Zuma, who turned 75 on Wednesday, has survived previous protests. But the main opposition party Democratic Alliance (DA) and other parties behind the protest believe they can drum up support to force Zuma out of office following his dismissal of respected Finance Minister Pravin Gordhan in a cabinet reshuffle.

South Africa’s economy has grown lethargically over the last six years and the jobless rate stands near record levels. Analysts say the


in one cable, or trunking between two switches.
Untag - What ports that will be a part of that vlan

Here is an example. I have one router, a switch, and 20 computers. I connect a cable to the router to the switch (backbone) on port 1. I then connect my computers on the switch from port 2-21.
Now i create the diffrent vlans, i create one that is named guestnet and one called companynet. I then untag the backbone (port 1) with both guestnet and companynet (if you dont want access to the internet on one of those vlans you dont untag the backbone with that vlan, then its just LAN only.)
Now i can untag the ports that the computers will connect to. I tag port 2-11 with guestnet andQ:

Every java program I try to start shows error

SOLVED, Program was in location with national symbol in it's path.
I just started studying java, but every program i try to start (even example ones from my course) shows an error.
Error: Could not find or load main class "Any class name of program I try start"
C:\Users\Mine\AppData\Local\NetBeans\Cache\8.1\executor-snippets\run.xml:53:           Java returned: 1
BUILD FAILED (total time: 0 seconds)

edit:
example of code, but happens to any code.
public class Hello {

    static void hello(){
        System.out.println("Hello, World!");

    }

    public static void main(String[] args) {
        hello();

    }
}

A:

This error means


that when Netbeans is invoking the JVM, the JVM cannot find the class file for the class Netbeans is telling it to run.  When you create a project in Netbeans, the classpath will be configured for you by the IDE, so you shouldn't normally see this error unless you have deleted the auto-generated main class and made a new one from scratch in the wrong place.
So the first thing to do is check what class Netbeans is using as the main class:
Right-click on the project name in the Projects tab and click on "Properties"

Then click on "Run" and check the name of the class in "Main Class":

Note in my example the class is called "tests.Test".  This means the class Test in the package "tests".  IntheBalm Balmshelter Tinted Moisturiser SPF18 - Light

Beskrivning

Perfect the look of your complexion with theBalm's BalmShelter Tinted MoisturiserSPF 18 in 'Light', a lightweight formula developed to even and smoothen the appearance of your skin.

Delivering a weightless veil of silky-smooth protection, the tinted moisturiser blends seamlessly to even out skin tone and improve texture, whilst shielding from damaging UV rays and hydrating the complexion. Expect a smoother, more refined looking canvas.


 },

  {
    question: "What rotates but still remains in the same place?",
    choices: ["Bottle (spin the bottle game)", "Clock", "Stairs"],
    correctAnswer: 2
  },

  {
    question: "How can you lift an elephant with one hand?",
    choices: ["Truck", "Use both hands!", "Use a lever", "There is no such thing"],
    correctAnswer: 3
  }
];
var currentquestion = 0;
var correctAnswers = 0;

function setupOptions() {
  $('#question').html(parseInt(currentquestion) + 1 + ". " + allQuestions[currentquestion].question);
  var options = allQuestions[currentquestion].choices;
  var formHtml = '';
  for (var i = 0; i < options.length; i++) {
    formHtml += '<div><input type="radio" name="option" value="' + i + '" id="option' + i +when I'm on the road alone, at night.
I could get off and press the pedestrian crossing button; but instead I stop (completely), wait until it's safe (no cars within 100m), and then cycle across against the light.
This type of traffic light happens where a minor residential street crosses a main road. I don't see how that intersection could be redesigned: without a traffic light, in daytime where there's nearly continuous traffic on the main road, the occasional cars on the smaller road  would never be able to cross the main road. And it wouldn't be worth putting roundabouts there IMO.

A:

Redesign road intersections instead of making new laws
In most situations where the discussion centres around "there are some examples where cyclists can safely jump a red light" rather


China is challenging India's long-held position as the dominant outside power in Nepal (Representational)

Highlights China and Nepal finalised a protocol during a meeting in Kathmandu

Nepal depends heavily on India for the supply of essential goods

China is making fast inroads into Nepal with aid and investment

China will allow Nepal the use of four of its ports, the Nepalese government said on Friday, as the landlocked Himalayan nation seeks to end India's monopoly over its trading routes by increasing connections with Beijing.

Wedged between China and India, Nepal depends heavily on India for the supply of essential goods including fuel and the use of its ports for trade with other countries.

But Kathmandu has sought access to Chinese ports to reduce dependence on India since a prolonged blockade of its border crossingsyour baby along on your runs? You might look for a jogging stroller, too.

Accessories.

Do you want your baby's stroller to have certain features or accessories, such as a storage basket, rain cover, blanket, sun shade or cup holder? Often, accessories are sold separately. Some strollers aren't compatible with certain accessories.

What type of stroller is safe for a newborn?

If you plan to use a stroller while your baby is a newborn, you'll need to make sure that the stroller reclines - since newborns can't sit up or hold up their heads.

Some strollers fully recline or can be used with a bassinet attachment or an infant-only car seat. However, most umbrella strollers typically don't provide adequate head and back support for young babies.

Also, most jogging strollers aren't designed to recline.


you'll be notified in case of a recall. If you're considering a used stroller for your baby, make sure the stroller hasn't been recalled.

Whether you're using it on a daily basis, for occasional errands or weekly jogs, a stroller can be a parenting must have. By consistently following safety rules, you can help ensure an enjoyable ride.

1998-2014 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Terms of Use.

Image: Getty Images

Stroller Safety: Tips for Parents

With so many types of strollers how do you choose? Learn how to pick the best stroller for your baby and important stroller safety tips.

It’s baby’s first big move to becoming an independent little person: her first steps! Here are the five gross motor milestones that precede baby’s ability to walk.

It’s whatend up walking even earlier.

Standing

Though babies don’t start standing until about 7 months at the earliest, most begin building the muscles they need to stand by extending their legs and bouncing on your lap. Your baby will start to pull herself up by holding onto your leg or a piece of furniture. In the early months, she may get stuck in the standing position — a situation which can quickly become frustrating, especially if it results in a lot of falling down. You can help by gently lowering your baby into a sitting position until sitting becomes more natural. Most babies get the hang of standing (and sitting back down) by 14 months.

Walking

Break out your phone — the moment has finally arrived: Baby’s first steps! Learning to walk


name of "anti-terrorism".

~~~
jamesrcole
> _If you raise children in fear, they 're easy to manipulate into fear as
> adults._

An implicit claim in the quoted text is that one of the reasons people want to
implement such drills is to produce adults that will be easier to manipulate.
I think a claim like that requires some attempt at justification.

(And before anyone jumps to conclusions, the point I'm making is completely
independent of whether I think the drills are a good or bad thing).

~~~
AstralStorm
The justification is hard - you would have to run serious longitudinal
studies. By that point the damage (or not) is done. In fact this could be
considered an unsanctioned social experiment, doubly unethical because it is
ran on children and bypasses parental oversight.

Just consider what happens in quite heavily militarized countries such as
South[Dermal Clues to Systemic Diseases].
Many systemic diseases go along with dermal involvement. Only a few of systemic diseases show characteristic skin derangements directly leading to the diagnosis of the underlying disease. Ten of these entities are described within this article. Some of these are autoimmune diseases, such as systemic lupus erythematodes, dermatomyositis or the anti-synthetase-syndrome. Others are genetic diseases with benign or malignant neoplasias (Peutz-Jeghers-syndrome, neurofibromatosis, tuberous sclerosis, Birt-Hogg-Dubé-syndrome, Cowden-syndrome). Other genetically based diseases with typical skin manifestations are characterised by vascular malformations (Pseudoxanthoma elasticum and Osler-Weber-Rendu syndrome) or metabolic and structural organ defects (Morbus Fabry, cystic fibrosis). Being familiar with the typical skin-appearance of these diseases will allow physicians and general practitioners to make a timely diagnosis.


Not long after a massive earthquake and tsunami devastated Japan in 2011, washing whole towns out to sea, concerns grew that huge amounts of debris could wash up on California’s coast.

But as an estimated 70,000 Californians prepare to participate Saturday in the state’s annual coastal cleanup, the question remains: Where is it?

Very little tsunami trash has reached California, or other Pacific coastal states, even though the disaster happened 2 1/2 years ago.

Federal officials have confirmed only 35 objects from the tsunami that have come ashore in the United States and British Columbia, ranging from two large chunks of docks that washed up in Oregon and Washington state last year to a soccer ball found off an Alaskan island and traced back to a Japanese schoolboy.

The only verified tsunami+ 67. List the prime factors of y.
37
Let i(q) = -q**2 + 6*q. Let h be i(5). Let b = h - 4. What are the prime factors of 1 - (-9 - (0 - b))?
3
Let h(p) = -p**2 + 14*p - 11. Let j be -3 - -1 - 7*-2. List the prime factors of h(j).
13
Suppose 6*b + 4*g = 2*b + 20, -3*g = 4*b - 15. Suppose b = 4*c + 61 - 13. Let z = 3 - c. List the prime factors of z.
3, 5
Suppose -4 = -a, 5*d = -7*a + 3*a + 51. Let y = -4 - -7. Suppose -11 = -y*u + d. List the prime factors of u.
2, 3
Let b = 66 + -34. Let r = b