hip replacement surgery. Upon her admission, a physician discovered that Ms. Mack's blood pressure was extremely elevated and ordered that her blood pressure be monitored every four hours. Ms. Mack's medical records, however, indicate that such readings were not recorded on her chart and that the Hospital failed to check her blood pressure as part of her pre-operative anesthesia evaluation. Ms. Mack's doctors, therefore, were unaware of her high blood pressure at the time of surgery. An expert hired by Ms. Mack-Evans to review these records opined that Ms. Mack's blood pressure was so high at the time of her surgery that the procedure should have been postponed. Neither Ms. Mack nor her family was informed of her elevated blood pressure, however, and the surgery proceeded as scheduledexist as to whether Ms. Mack-Evans knew or should have known of the facts linking the Hospital to her mother's death as of the date her mother died. Indeed, the record indicates that, until her mother's medical records were obtained, Ms. Mack-Evans believed that the Hospital's only potential error was in re-sedating her mother following surgery. Ms. Mack-Evans had no knowledge of the Hospital's alleged failure to track Ms. Mack's blood pressure prior to surgery, nor did she know that a drop in blood pressure following surgery likely caused Ms. Mack to suffer from a stroke or other brain damage.
Moreover, several medical entities besides the Hospital treated Ms. Mack between the date of the surgery and the date of her death. Indeed, by the time Ms. Mack died


filed a complaint against Hilltop and nine other nursing home facilities. The complaint against the nursing home defendants also alleged personal injury and wrongful death theories of liability. On December 3, 2007, the separate actions against the nursing homes and the Hospital were consolidated. The record indicates that Ms. Evans was able to resolve the claims against the nursing homes and those defendants were dismissed from the case. The nursing home defendants are not involved in this appeal.
[7]  The personal injury claim was filed pursuant to W. Va.Code § 55-7-8a (1959) (Repl.Vol.2008). Under this statute, a personal injury claim may be filed by a decedent's representative if the injury alleged did not result in the death of the decedent. That is, under this statute, a personal injury-0.38 and 32749154469.
32749154468.62
What is -61.5327673572 plus 0.05?
-61.4827673572
Add together 0.5 and -6672779260.6693.
-6672779260.1693
38.8+42669081.36
42669120.16
Work out 835156586101 - 0.42.
835156586100.58
Add together 21.05 and 3.786571.
24.836571
What is -1.31 + -6478678826?
-6478678827.31
Subtract -5 from 60676988549.
60676988554
What is -56140711504 minus -37.29?
-56140711466.71
What is 0.3 - -0.03583350317641?
0.33583350317641
What is 1343181330 minus 0.0851?
1343181329.9149
7127091878 + 96
7127091974
What is 14653487261052 less than -92?
-14653487261144
Add together 2704 and -121388946.
-121386242
Work out 390150.79 + -88267.
301883.79
Calculate 547025024602 + -0.701.
547025024601.299
Calculate -95602 - 3805899294.
-3805994896
Total of -31 and -1052815141296.
-1052815141327
-2.733 - 750790.9415
-750793.6745
What is 0.83753 take away -354898.7?
354899.53753
-1882058731790 + 0.067
-1882058731789.933
What is the distance between -30145003062.6 and -7.53?
30145003055.07
Calculate -0.1906 - 1943769907.46.
-1943769907.6506
Calculate -19.07745 - 60310.94.
-60330.01745
823326 + 0.102354
823326.102354
What is -0.05 - -103645268597?
103645268596.95
Subtract -2.78557407 from 355286.
355288.78557407
What is 374715.2757631 plus 0.08?
374715.3557631
What is 2.3 minus -0.070703202452?
2.370703202452
Work out -36 + -5086331409.
-5086331445
Calculate 0.08 + -4248330814023.
-4248330814022.92
What is 196092270 plus -3062?
196089208
Sum -0.20205 and -3419844.
-3419844.20205
Calculate 3.53835622 + -151.
-147.46164378
What is -4927384517 take away -12445?
-4927372072
Sum 103809 and 29808642.81.
29912451.81
-0.44+378622.92747
378622.48747
What is


Non-peptidic α-helical mimetics as protein-protein interaction inhibitors.
Protein-protein interactions play a major role in almost all biological pathways and thus, these interactions have a profound impact on the pathogenesis of diseases. The ability to modulate protein-protein interactions with small molecules is an important and rapidly growing area in the field of medicinal chemistry. One of the most common secondary protein structures that are involved in protein-protein interactions are α-helices. Thus, a common approach towards developing inhibitors of protein-protein interactions is to design non-peptidic small molecules that mimic the spatial orientations of the side chains of an α-helix. In this review, we will discuss a variety of small molecules including terephenyls, terephthalamides, benzamides, enaminones, benzoylureas, pyridines, imidazoles, thiazoles, pyridazines, piperazines, oxopiperazines and diphenylindanes that have been published from 2005-2010 asis giving carriers some sway in the development of its smartphones, but given the latest leak, it seems that some of the more egregious customizations and bloat might stay on the sidelines. As for the back of the device, with a label that reads "XFON," well, we'll leave that to your interpretation.


opinion states that it came to the 40-year line not on its own, but by interpreting the legislative intent from a 2016 law that determined the mandatory minimum sentence for a subset of juvenile offenders who commit murders of police officers, among other heinous crimes. “This specific number does not originate in court decisions, legal literature, or statistical data. It is not drawn from a hat,” Neville wrote in the opinion. “Rather, this number finds its origin in the entity best suited to make such a determination—the legislature.”

The ruling could have wide implications across the state. Before the legislature in 2016 amended the law, giving judges discretion to ignore previously mandatory firearm sentencing terms, juvenile offenders who committed murder with a firearm faced a mandatory minimum prison termof 45 years. Now, many of those offenders will be eligible for resentencing because the court did not have the discretion to adequately consider their youth.

Shobha Mahadev, an attorney with Northwestern University’s Children and Family Justice Center, said it is difficult to say exactly how many individuals the ruling will affect, especially because questions remain regarding what qualifies as adequate consideration of youth.

“For sentences that proceeded everything we know about kids and development, anything sort of before the past decade, I would be skeptical as to whether those sentences really took youth into account,” Mahadev said.

Last May, Injustice Watch reported on the more than 160 juvenile offenders set to serve more than 50 years in prison, including roughly 40 inmates with life terms. At that time, about 60


Q:

Why does Code::Blocks keep crashing when I try to run this code?

Code::Blocks keeps crashing when I enter the first score in this simple code. It is a perfectly type code to my understanding now I'm confused.
#include <stdio.h>
#include <stdlib.h>

int main() {
    float grade = 0;
    float scoreEntered = 0;
    float numtest = 0;
    float average = 0;

    printf("Press 0 when complete. \n\n");
    do {
        printf("Test: %.0f   Average: %.2f \n", numtest, average);
        printf("\nEnter test score ");
        scanf("%f", scoreEntered);
        grade += scoreEntered;
  result)
			result = readTagLine (file);  /* read complete line */
	}
	return result;
}

static int nameComparison (tagFile *const file)
{
	int result;
	if (file->search.ignorecase)
	{
		if (file->search.partial)
			result = tagnuppercmp (file->search.name, file->name.buffer,
					file->search.nameLength);
		else
			result = taguppercmp (file->search.name, file->name.buffer);
	}
	else
	{
		if (file->search.partial)
			result = tagncmp (file->search.name, file->name.buffer,
					file->search.nameLength);
		else
			result = tagcmp (file->search.name, file->name.buffer);
	}
	return result;
}

static void findFirstNonMatchBefore (tagFile *const file)
{
#define JUMP_BACK 512
	int more_lines;
	int comp;
	off_t start = file->pos;
	off_t pos = start;
	do
	{
		if (pos < (off_t) JUMP_BACK)
			pos = 0;
		else
			pos = pos - JUMP_BACK;
		more_lines = readTagLineSeek (file, pos);
		comp = nameComparison (file);
	} while (more_lines  &&  comp == 0  &&  pos > 0  &&  pos < start);
}

static tagResult findFirstMatchBefore (tagFile *const file)
{
	tagResult result = TagFailure;
	int more_lines;
	off_t start = file->pos;
	findFirstNonMatchBefore (file);
	do
	{
		more_lines = readTagLine (file);
		if (nameComparison (file) == 0)
			result = TagSuccess;
	} while (more_lines  &&  result != TagSuccess  &&  file->pos < start);
	return result;
}

static tagResult


by the induction of the electroneutral 2H+/Me2+ exchange after starvation. The disproportion in the amounts of linoleic and docosahexaenoic acids in mitochondrial phospholipids after starvation is considered to be the possible cause of the changes in the structure and permeability of the mitochondrial membrane.and 52 (90%) in the placebo group completed the study.

The trial’s primary objective was to assess reductions in patients’ disease activity through the ankylosing spondylitis disease activity score (ASDAS), a validated measure of disease activity based on the scores of five domains: back pain, joint pain and/or swelling, morning stiffness, global assessment of disease activity, and levels of C-reactive protein (a blood marker of inflammation).

Secondary goals included determining the proportion of patients who achieved at least a 20% (ASAS20) or 40% (ASAS40) improvement in at least three of the four main domains of Assessment of Spondyloarthritis international Society (ASAS) — physical function, pain, patient global assessment, and inflammation — and patients’ quality of life – assessed through Ankylosing Spondylitis Quality of Life questionnaire (ASQoL).

Results showed that reductions in


and then handed it to the other crew member, who also drank from the same can.”

“The beer was laced with a drug, and after that point, the rest of the night became a blur for Doe # 1, Doe # 2 and the other crew member,” the complaint alleges. At some point, the two pilots and the three crew members allegedly went to a hotel, the complaint alleges.

“Plaintiff, in a haze from being drugged, next became aware that she was in bed with [Defendant #1] and her fellow crew member,” the complaint alleges. “The Defendant was on top of Plaintiff raping her.”

“The Plaintiff felt the influence of the drug that the defendant laced the beer with,” the complaint alleges, “and Plaintiff was unable to react to the situation,Q:

SpriteKitでのphysicsBodyを用いた当たり判定の流れ知りたい

私は殆ど、参考になりそうなウェブサイトを頼りに書き写したりして作業をしているのですが、PhysicsBodyでの当たり判定についてはそれだけではロジックの理解に繋がりませんでした。すごく単純な話ではありますが、こちらで質問させてください。

まず、physicsBody.contactTestBitMaskについてなのですが
この値が一体何をしているのかがわかりません。
使い方は
foo, barいずれもphysicsBodyを持った状態で、一度
foo.physicsBody.contactTestBitMask = bar.physicsBody.categoryBitMask

としておくだけで、fooの剛体がbarの持つカテゴリの世界線において何らか（スプライトノードなど）と衝突あるいは重なっている状態であれば
SKPhysicsContactDelegate下の
didBegin(_ contact: SKPhysicsContact)関数内の処理が呼び出されるという認識で間違い無いのでしょうか。
であれば一体前述した1行のコードで何が行われているのでしょうか、何もトグル（発火）しているようには見えません。ただの代入なのでしょうか。

このような質問をするのは他でもなく、私はこの当たり判定の実装に成功できていないからなのですが、どのような仕組みなのかを理解するだけでも解決につながるかもしれないので、この場をお借りしました。
ご回答のほどよろしくお願いいたします。

A:

使い方は foo, barいずれもphysicsBodyを持った状態で、一度
foo.physicsBody.contactTestBitMask = bar.physicsBody.categoryBitMask

としておくだけで、fooの剛体がbarの持つカテゴリの世界線において何らか（スプライトノードなど）と衝突あるいは重なっている状態であれば
  SKPhysicsContactDelegate下の　 didBegin(_ contact:
  SKPhysicsContact)関数内の処理が呼び出されるという認識で間違い無いのでしょうか。

いいえ。そのようなコードで当たり判定(接触検出)が出来るのは極めて限定的な場合だけです。
(そんなコードだけを十分な解説も無しに載せているサイトを「参考になりそうなウェブサイト」として頼りにするのはやめた方が良いでしょう。）

BitMaskの働きを完全に理解するにはある程度2進法についての理解が必要です。基本は以下のような感じ。
class GameScene: SKScene, SKPhysicsContactDelegate {

    private var player: PlayerNode?
    private var enemy1: EnemyNode?
    private var wall: SKShapeNode?

    override func didMove(to view: SKView) {
        physicsWorld.contactDelegate = self

        //適切な`SKPhysicsBody`をもったノードが存在するものとする
        player = PlayerNode(imageNamed: "player")
        player!.physicsBody = SKPhysicsBody(circleOfRadius: 12)
        enemy1 = EnemyNode(imageNamed: "enemy1")
        enemy1!.physicsBody = SKPhysicsBody(circleOfRadius: 12)
        wall = SKShapeNode(rect: CGRect(x: 0, y: 0, width: 384,


height: 12))
        wall!.physicsBody = SKPhysicsBody(rectangleOf: CGSize(width: 384, height: 12))
        //...
        //ノードのカテゴリー(分類)ごとに`categoryBitMask`を設定する
        player!.physicsBody!.categoryBitMask = 0b00000000_00000000_00000000_00000001
        enemy1!.physicsBody!.categoryBitMask = 0b00000000_00000000_00000000_00000010
        wall!.physicsBody!.categoryBitMask   = 0b00000000_00000000_00000000_00000100
        //接触判定をしたい相手の`categoryBitMask`を自分の`contactTestBitMask`に設定する
        player!.physicsBody!.contactTestBitMask = 0b00000000_00000000_00000000_00000110
        enemy1!.physicsBody!.contactTestBitMask = 0b00000000_00000000_00000000_00000111
        wall!.physicsBody!.contactTestBitMask   = 0b00000000_00000000_00000000_00000011
        //各ノードをシーン内に置いたり、初期速度を与えたり…
        //...
    }

    funcI thought I should ask the community.
EDIT: The object is a binary tree, and used as a decision tree. The code is basically an API that is required to quickly return an answer from the tree. This all needs to perform at an ever increasing rate so I am trying to maximize the performance wherever possible.

A:

As far as I'm aware, it's not possible to cache objects in PHP without serializing.  In general, however, caching mechanisms (APC, Memcache, etc) are really trying to remove the db connection(s) more than improve performance (and thereby decrease the overall DB strain). This is definitely how memcache, et al are employed with regards to Drupal. In other words, the caching mechanisms should allow you to scale, though they may not


traditional DBMS such as Oracle. Other than among those, Couchbase doesn’t compete much yet with Oracle et al.

Pure CouchDB isn’t all that much of a business, at least relative to community size, as CouchDB is a single-server product commonly used by people who are content not to pay for support.

Membase sales are concentrated in five kinds of internet-centric companies, which in declining order are: Read more

It makes little sense to talk of Facebook’s use of “MySQL.” Better to talk of Facebook’s use of “MySQL + memcached + non-transparent sharding.” That said:

It’s hard to see why somebody today would use MySQL + memcached + non-transparent sharding for a new project. At least one of Couchbase or transparently-sharded MySQL is very likely a superior alternative. Other alternatives might be betterIn refrigerating storehouses, inner walls are covered with frost, which is formed from moisture contained in air and objects stored in the storehouses. If such frost is left unremoved, the walls are gradually covered with ice, resulting in a considerable drop in thermal efficiency of the refrigerating storehouses. Therefore, frost and ice must be removed periodically. In order to remove frost and ice, objects in a refrigerating storehouse must firstly be moved to the outside while refrigeration is temporarily stopped, and the defrosting operation is performed manually.
In order to solve the above problems, there have heretofore been proposed chemical compositions for preventing icing; for example, a thickening organic composition formed from water-miscible organic liquid with alumina (Patent Document 1). However, such an organic composition is not suited for


: left;

      for (right_x = left_lim; right_x < right_lim; right_x++) {
	ptr_left = left_corner;
	ptr_right = right_corner;

	if ((y == top) && (right_x == left_lim)) { /* If top left hand corner */
	  for (i = 0; i < y_window_size; i++) {
	    for (j = 0; j < x_window_size; j++) {
	      left_pix = (unsigned int) *ptr_left;
	      right_pix = (unsigned int) *ptr_right;

	      sum +=  (right_pix - left_pix) * (right_pix - left_pix);

	      ptr_left++;
	      ptr_right++;
	    } /* for j */

	    ptr_left += incr;
	    ptr_right += incr;
	  } /* for (i = 0; i < x_window_size; i++) {
	    left_pix = (unsigned int) *(ptr_left);
	    right_pix = (unsigned int) *(ptr_right);

	    sum += (right_pix - left_pix) * (right_pix - left_pix);

	    ptr_left ++;
	    ptr_right ++;
	  } /* for i */

	  prev_sum = sum;

	} else {
	  ptr_left--; ptr_right--;

	  for (i = 0; i < y_window_size; i++) {
	    left_pix = (unsigned int) *(ptr_left);
	    right_pix = (unsigned int) *(ptr_right);

	    /* subtract first column of previous window */
	    sum -= (right_pix - left_pix) * (right_pix - left_pix);

	    ptr_left += x_window_size;
	    ptr_right


in fiscal 2017 is to get back the sales it lost in fiscal 2016. Beyond that, Argir said, the aim “is to get back to a growth rate, because if you remember, [e-commerce] in our business had been declining for several years.” Argir said he expects sales at BN.com to start to improve in the second half of fiscal 2017.

Barnes & Noble Inc. Fiscal 2015–2016 Segment Results

($ in millions)

Sales Year Ended Year Ended Segment May 2, 2015 Apr. 30, 2016 Change Retail $4,108.2 $4,028.6 -1.9% Nook $263.8 $191.5 -27.4% Intercompany Elimination ($74.9) ($56.3) — Total $4,297.1 $4,163.8 -3.1% EBITDA Year Ended Year Ended Segment May 2, 2015 apr. 30, 2016 Change Retail $317.7 $215.5 -32.2% Nook ($83.9) ($64.7) — Total $233.8 $150.5 -35.9%

Source: Barnes & Noble

Barnes & Noble,the OpenStack trademark and in fact not delivering OpenStack functionality or characteristic. The OpenStack Foundation is forming a committee with the purpose of
defending the OpenStack trademark for commercial product claiming to be
powered by OpenStack by defining - DefCore.

What is DefCore?
DefCore establishes the required minimum feature set for OpenStack products. As mentioned in the above paragraph, this applies to commercial products only. According to Rob Hirschfeld(@zehicle) a member of the OpenStack Foundation, DefCore is a process that defines:

capabilities

designated sections of code

must-pass tests

These definitions use community resources and involvement to drive interoperability by creating the minimum standards of products labeled as - OpenStack™

DefCore Guiding Principles
While this is still in working process by the OpenStack Foundation DefCore committee, currently there are a list of "guiding principle" listed in GitHub:

Implementations that are


Core can use OpenStack trademark (OpenStack™)

Core is a subset of the whole project

Core definition can be applied equally to all usage models

Claiming OpenStack requiring use of designated upstream code

Projects must have an open reference implementation

Vendors may substitute alternate implementations

Tests can be remotely or self-administered

A subset of tests are chosen by the Foundation as "must-pass"

The OpenStack board owns the responsibility to define 'core' – to approve 'musts'

At the OpenStack Vancouver summit, Jonathan Bryce at the keynote announced 16 companies has passed this test and is certified to bare the OpenStack label in their product. These are the 16 companies that are certified:process, a large number of installation parts are coupled together by means of the steel slab or steel strip. An interruption at one of the installation parts means that the entire device, or a large part of the device, has to be shut down. This interruption may be unplanned or planned, for example in order to change rollers. In order to be able to cope with interruptions of whatever type, a further design of the process according to the invention is characterized in that the furnace device is used as a buffer space for the temporary storage of slabs in the event of interruption to one of the parts of the installation for processing slabs which have been welded together. The furnace device can act as a buffer


an amazing job at capturing the on screen character in a tidy poseable package.

In fact the whole thing is so tidy he comes with barely any accessories. Granted there really isn't a whole lot Shellhead the First needs other than a pair of hands, but you do get a Revocontainer, a name badge, a display base, and a flame effect part to round out the toy.

Of course the real draw of this figure isn't the number of bits in the box, but the amount of detail etched into its surface. This all PVC plastic toy has a terrific worn metallic sheen to its surface complete with tampographed lettering that emulates the look of the movie suit.

Tiny wires and hydraulic lines go in and out of crevasses all aroundchose to depict.

The hips in particular utilize a traditional universal joint rather than any Revoltech pieces that work in conjunction with a thigh swivel to give Tony the ability to sit. Kaiyodo advertised this pose on the back of the box as a good indication of what this toy can do.

The Mark 1 also features a pair of moving side skirts that hinge out of the way of the legs while still allowing the whole thing to look attached. Note that the codpiece is made out of soft PVC and may need to be moved out of the way to return the skirt pieces to their default position.

For an extra ab crunch, the Mark 1 has this large hinged block topped off with a big Revoltech joint hidden


and perfectly captures the spirit of the makeshift weapon Tony cobbled together back in Tales of Suspense #39. I was delighted to see something that was both so old-fashioned in aesthetics lovingly realized in a believable way. This is the armor fans and hobbyists have been making for decades and the people behind the film paid a fittingly heavy metal tribute to it.

Running as fast as they can...

IRON MAN LIVES AGAIN!

The Revoltech Iron Man Mark 1 is an amazing figure. It's the kind of toy that tells all the other six-inch Iron Mans to pack up and go home if they can't measure up to its scrap metal majesty. It has all the strengths of a Revoltech with almost none of their weaknesses. My only major issue withair fails to operate at its maximum performance, thereby deteriorating the durability of parts.
Cooling fans often become contaminated with dust over time, reducing their performance and deteriorating the performance of the vehicles. Further, in order to repair them, battery modules are withdrawn and fans are replaced and remounted.
The items described as the background art are included only to help understanding of the background of the prevent invention, and should not be construed to admit that it corresponds to the conventional technology known to those skilled in the art.


Cheryl,

They were changed when I sent you the e-mail.

Thanks

	Enron North America Corp.

	From:  Cheryl Luster                           02/08/2001 01:45 PM

To: Errol McLaughlin/Corp/Enron@ENRON
cc:

Subject: Re: EOL deals for Utilicorp

Kim Theriot asked me to make sure that these EOL deals are changed in TAGG.
(Deals listed below.)
Please let me know when they are completed.

Thanks.
Cheryl
x. 54774

Errol McLaughlin
02/07/2001 10:22 AM
To: Cheryl Luster/NA/Enron@ENRON
cc: Rebecca Ford/HOU/ECT@ECT

Subject: Re: EOL deals for Utilicorp

The ordeal is finally over!  These deals are to be settled as NYMEX swaps.

Thanks,

Errol

	Enron North America Corp.

	From:  Cheryl Luster that haplotype analysis with mixed population be avoided.

Using a mixed ethnic sample may also induce population stratification. This can cause false associations since the pattern of genetic variations as well as pain rating is not uniform between ethnic populations \[[@B7]\], requiring use of homogenous population in genetic association studies \[[@B8]\]. Considering significant differences of allele frequencies and pain sensitivities among ethnic populations, it would be more informative to analyze single ethnic origin population only compared to the total mixed sample to determine if the apparent association is due to population stratification.

Another possible reason of inconsistency is the pain phenotype. Because responses to different types of painful stimuli are genetically dissociable \[[@B9]\], *GCH1*genetic variation may affect the responses to a specific type of painful stimulus, while not influencing other


Sure we’ve heard about you before, but we think it’s time for Tone Deaf to get to know you a little better. Slip in to something comfortable while we put on some music, pour us a couple of drinks and turn the lights down low.

Who are you and what do you do in your act?

My name is Adam and I do everything in CROPS. Singing, playing, production.

‘Fess up. What records have you stolen from your parents’ record collection and why?

My parents had a lot of Beatles and Bowie, Pink Floyd I think too, and Jimi Hendrix. Lots of good stuff. I seem to remember I spent a lot more time staring at the LP covers than playing them though.

What’s on heavy rotation on your iPod right now?

I’ve beenand secondly they had to care enough to bother to make one. At the time it was also more a labour of love to create a physical thing and treasure it, or if you bought the record you would have all the cover art etc. and treasure that. These days an mp3 is an mp3 with very little emotional investment in the format no matter where it came from.

You must answer this question honestly or we steal your rider. What was the first gig you went to.?Where was it and what was the venue?

I’m pretty sure it was Terrorvision somewhere in Bedforshire…. Whales and dolphins, man.

What’s your favourite site to download music from and do you ever pay for it? Can we find any of your releases there?

I’ve


the season we are going to be in trouble.’

The United boss also had pop at the American match officials conceded two penalties against Liverpool. ‘The referee was called in by mistake,’ he added. ‘They must have been called in by the baseball federation because they didn’t have soccer in their heads. It was fun.’short-circuit

1[intransitive,transitive]short-circuit (something)to have a short circuit; to make something have a short circuitThe wires had short-circuited and burned out.

2[transitive]short-circuit somethingto succeed in doing something more quickly than usual, without going through all the usual processesThe process of becoming a politician can be short-circuited if you are already a well-known public figure.


import { TimelineGridWrapper } from './TimelineGridWrapper'
import { getBoundingRect } from 'fullcalendar-tests/lib/dom-geom'
import { findElements } from '@fullcalendar/core'
import { getRectCenter, addPoints } from 'fullcalendar-tests/lib/geom'
import { CalendarWrapper } from 'fullcalendar-tests/lib/wrappers/CalendarWrapper'

export class ResourceTimelineGridWrapper {

  base: TimelineGridWrapper

  constructor(public el: HTMLElement) {
    this.base = new TimelineGridWrapper(el)
  }

  getRootEl() {
    return this.base.el
  }

  click(resourceId: string, date) { // not JUST a date. a resource too
    let point = this.getPoint(resourceId, date)

    if ($(this.el).css('direction') === 'ltr') {
      point.left += 1
    } else {
      point.left -= 1
    }

    return new Promise((resolve) => {
      $.simulateByPoint('drag', {
 nothing more than speculation to support plaintiffs' claim of alleged competitive advantages of California competitors; and that there is no evidence to prove either price discrimination or a conspiracy to monopolize trade on Standard's part. California repeatedly argues that the allegations of lower Texas prices for the purpose of tempting Ingram's Clovis customers are insufficient to support plaintiffs' claims.
Gulf contends that the western Texas and eastern New Mexico regions involved herein are separate market areas, and that therefore Gulf operators in Texas cannot be deemed competitors of Ingram. Gulf also argues that Ingram has suffered no harm and has failed to discover any evidence beyond mere speculation of conspiracy to monopolize in restraint of trade.
Phillips relies primarily upon the joint memorandum filed by all six defendants, but urges


(1954). However, such behavior may, even without previous agreement, be found to violate the anti-trust laws. See Bigelow v. RKO Radio Pictures, 327 U.S. 251, 66 S.Ct. 574, 90 L.Ed. 652 (1946). Nor need there be simultaneous action or agreement *679 to constitute an unlawful conspiracy. See William Goldman Theatres v. Loew's Inc., 3rd Cir. 1945, 150 F.2d 738. There need be no express agreement, written or otherwise, and intent to conspire is not necessary if unlawful restraint of trade results from improper conduct. See Esco Corp. v. United States, 9th Cir. 1965, 340 F.2d 1000; Spears Free Clinic and Hospital for Poor Children v. Cleere, 10th Cir. 1952, 197 F. 2d 125. In light of the liberality allowed in the proof of a claim of conspiracy underthe anti-trust laws, in view of the fact that such proof is invariably difficult to uncover by a private litigant, the award of summary judgment on the conspiracy count in this case must be denied. A trial will afford to plaintiffs a better opportunity to establish the contention that the defendants' conduct is a part of a conspiracy on their part.
Assuming, arguendo, that the New Mexico statutes involved apply only to intra-state commerce, D. L. Ingram's affidavit accompanying plaintiffs' opposition to the motions to dismiss avers that plaintiffs complain of unfair competition within New Mexico as well as between New Mexico and Texas distributors. As pointed out above, the mere fact that Ingram's volume has increased does not negate the possibility of actual harm. Thus, the motions to


and Georgia Institute of Technology (GA Tech) to form the Atlanta Clinical and Translational Science Institute (Atlanta-CTSI). This strategic multi-institutional alliance offered compelling and unique advantages. Emory is one of the nation's leading healthcare and academic research institutions, ranking 19th nationally in NIH funded research;GA Tech is a national leader in biomedical engineering and the application of innovative systems engineering to health care solutions;and MSM is a historically black medical school recognized as a national leader in expanding the ethnic diversity of biomedical research, dedicated to community engagement in efforts to eliminate health disparities and serving as a pipeline for training minority investigators. The established partnerships and diverse faculty enable the Atlanta-CTSI to combine strong clinical, translational, training and basic discovery programs at Emory with the health disparities,Q:

Is there a utility to take an oracle dump into Google BigQuery?

Hello all :) I'm having problems moving data to Google's BigQuery from an Oracle 10g server.
Is there a program or library that takes an Orale dump and mounts it on BigQuery?
I have searched extensively and have encountered no solution so far. I'm posting here with the BigQuery tag in the hope that someone has done it but didn't document it on the internet.
Best regards

A:

I haven't used it, but would OraDump-to-CSV work for you?
http://www.convert-in.com/ord2csv.htm
Once you have a CSV, you can easily import it in into BigQuery.


 What is the third derivative of d(l) wrt l?
18
Let y(l) = -l - 1. Let v(j) = -j**2 + 6*j + 10. Let t(u) = -v(u) - 3*y(u). Let s be t(5). Find the second derivative of -4*m**3 - 2*m**4 + 4*m**s + m wrt m.
-24*m**2
Let o(m) = m**3. Let r(w) = 21*w**3 - 19. Let h(u) = 6*o(u) + r(u). What is the first derivative of h(i) wrt i?
81*i**2
What is the third derivative of 7707*v**2 - 9*v**6 + 2*v**6 - 7712*v**2 wrt v?
-840*v**3
Let o(w) be the third derivative of w**9/15120 + w**7/5040 - w**5/15 - w**2. Let p(n) be the third derivative of o(n). Find the second derivative of p(a) wrt a.
24*a
Let t(o) = 27*o**3 + 25*o**2 + 6. Let z(l) = l**3 - 1. Let  <xsl:for-each select="day-model">
            <xsl:variable name="day-model-properties">
                <day-model-deleted>
                    <xsl:value-of select="deleted"/>
                </day-model-deleted>
                <day-model-color>
                    <xsl:value-of select="color"/>
                </day-model-color>


Fine-grained auditory discrimination and performance on tests of receptive vocabulary and receptive language.
This research investigated the relation between children's performance on two measures of receptive language and children's auditory discrimination of consonant-vowel sounds having frequency and temporal acoustic differences. The measures of fine-grained auditory discrimination produced significant multiple regression coefficients against both receptive vocabulary (Peabody Picture Vocabulary Test-Revised) and receptive language (Token Test for Children) scores. Validation analyses conducted by predicting receptive vocabulary and language scores for a new sample of children and relating them to the actual scores led to significant outcomes. It was concluded that fine-grained auditory discrimination is particularly important in the relatively early stages of language learning.“Some People Call Me Obsessive Or Driven Or Lucky Or Whatever. I’m All Of Those Things. Shouldn’t We All Be?” – Kelly Slater

In positive psychology, flow, also known as zone, is the mental state of operation in which a person performing an activity is fully immersed in a feeling of energized focus, full involvement, and enjoyment in the process of the activity.

In essence, flow is characterized by complete absorption in what one does.

About Kelly Slater

Robert Kelly Slater (born February 11, 1972) is an American professional surfer known for his competitive prowess and style. He has been crowned World Surf League Champion a record 11 times, including 5 consecutive titles in 1994–98. He is the youngest (at age 20) and the oldest (at age 39) to win the title.

Upon


-> Option(System.getProperty(name))
    }

    System.setProperty(Context.INITIAL_CONTEXT_FACTORY, "org.apache.naming.java.javaURLContextFactory")
    System.setProperty(Context.URL_PKG_PREFIXES,        "org.apache.naming")

    def createSubcontextIgnoreIfBound(ic: InitialContext, name: String) =
      try {
        ic.createSubcontext(name)
      } catch {
        case _: NameAlreadyBoundException => // ignore
      }

    new InitialContext                                         |!>
      (createSubcontextIgnoreIfBound(_, "java:" Q:

How to add conditional transitions?

This question is about transitions with d3.js, e.g. the change of the x attribute of a rectangle.
If you want the change to occur immediately you may set delay = duration = 0 as in
svg.selectAll("rect")
   .transition()
   .delay(delay)
   .duration(duration)
   .attr("x", 0)

but this may be too expensive (assuming that transitions are more CPU consumpting than immediate changes). So how can I add the transition conditionally, behaving like
if (delay == 0 && duration == 0) {
    svg.selectAll("rect")
        .attr("x", 0)
} else {
    svg.selectAll("rect")
        .transition()
        .delay(delay)
        .duration(duration)


that regular selections and transition selections have different methods with the same name, like selection.on() and transition.on().
Here is the first demo. All the rects are in x = 10. The selection is turned into a transition selection:

d3.selection.prototype.conditionalTransition =
  function(cond1, cond2) {
    return cond1 && cond2 ? this.transition().duration(duration).delay(delay) : this;
  };

const rect = d3.selectAll("rect");

const delay = 100,
  duration = 1000;

rect.conditionalTransition(delay, duration)
  .attr("x", 200)

function transitioning(sel) {
  return sel.transition()
    .delay(delay)
    .duration(duration);
}
<script src="https://cdnjs.cloudflare.com/ajax/libs/d3/5.7.0/d3.min.js"></script>
<svg>
 <rect x="10" y="10" width="50" height="20" fill="teal"></rect>
 <rect x="10" y="40" width="50" height="20" fill="teal"></rect>
 <rect x="10" y="70" width="50" height="20" fill="teal"></rect>
 <rect x="10" y="100" width="50" height="20" fill="teal"></rect>
</svg>

And here is the same code, with both delay and duration equal to zero. As you can see the rectangles are alreadydoes not exceed in absolute value $({2e \over c})^d$.For each $\rho \geq 0$ put $V_\rho(P) =
\{z\in {\mathbb C}, \ \vert P(z) \vert \leq \rho\}.$ Since by assumptions $\vert P(x) \vert \leq 1$ on $Z$ we have $Z\subset V_{1}(P).$ By the definition of $c_d(Z)$ we conclude that for every covering of $V_{1}(P)$ by $d$ disks $D_1,\dots,D_d$ of the radii $r_1,\dots,r_d$ (which is also a covering of $Z$) we have $\sum_{i=1}^d r_i \geq c_d(Z)$. Denoting the absolute value of the leading coefficient of $P(x)$ by $A$ we have by the Cartan lemma that for a certain covering as above $c=c_d(Z)\leq \sum_{i=1}^d r_i \leq 2e({1\over A})^{1\over d}.$ We conclude that $A\leq ({2e \over c})^d$. $\square$

Now we write $P(x)=A\prod_{j=1}^d (x-x_j), \ x_j \in {\mathbb C},$ and consider separately two cases:

1\. $\vert x_j


finite and infinite values. These singularities appear at zeroes of $s_d(x)$ and at zeroes of the discriminant $\Delta(x)$ of the equation (5.1). Consequently, their number does not exceed $r=r(d)=d+d(2d-1)=2d^2$. Let us denote the singular points of $h(x)$ by $\Sigma=\{x_1,\dots,x_r\}$.

Equivalently, we can consider an algebraic curve $Y\subset {\mathbb C}^2$ defined by the equation $Q(x,y)=0,$ and its projection $\pi_1$ to the $x$-axis in ${\mathbb C}^2$. The algebraic function $y=h(x)$ is then a (multivalued) inversion of $\pi_1$.

For a complex polynomial $P(x,y)$ of degree $d_1$ consider $g(x)=P(x,h(x))$. $g(x)$ is once more an algebraic function. Its singularities are the same as for $h(x)$. Fix a certain non-singular point $x_0$ and denote $R$ the distance of $x_0$ to the nearest singularity $x_i$. Now let us fix a regular branch $\tilde g(x)$ of $g(x)$ atC}\setminus \Sigma$, which we fix. Consider now all the branches of the algebraic function $y=h(x)$ as above. We fix a certain (regular and univalued) branch $\hat h(x)$ of $h$ over $D$. Now let us fix a point $x_0\in {\mathbb C}\setminus \Sigma$ and one of the branches $\bar h(x)$ of $h$ over a neighborhood of $x_0$.

The definition of the constant $K(S)$ below depends only on the geometry of $\Sigma$, on the position of $x_0$ and $Z$ in ${\mathbb C}\setminus \Sigma$, and on the “combinatorial" data: the degrees $d, \ d_1$, the monodromy group $G$ of $h$, and on the choice of the branches $\hat h, \bar h$ of the algebraic function $h$. Accordingly, we shall consider “configurations" $S=\{d,d_1,\Sigma, Z, x_0, G, \hat h, \bar h \}$ and notice that


Puthukulam
 Paithakulam.

Education
1) Infant Jesus High School for girls, Mulagumoodu.

2) Infant Jesus Teacher Training Institute for women, Mulagumoodu.

3) St.Joseph's Hr.Sec.School, Mulagumoodu.

4) St.Joseph's Matriculation Hr.Sec.School, Mulagumoodu.

5) Pope John Paul II College of Education, Mulagumoodu.

6} Fr.victor Library, Mulagumoodu.

7) St. Aloysius Library, Mulagumoodu.

8) Infant Jesus Arts and Science College for women, Mulagumoodu

Religious
Mulagumoodu Includes many Religious worship centres,Churches and Temples.
St.Mary Church
HMS Church Pandarakonam
The Salvation Army Church Kurumankuzhy
St.Paul CSI Church
Pentecostal Church

References

Category:Cities and towns in Kanyakumari districtrecommended that she bring it to experts to be evaluated. The painting hadn't attracted much attention from the woman, who is in her 90s, or her family, who thought it was an old icon from Russia, according to The Guardian.

Acteon Auction House, which sold the masterpiece to the anonymous buyer, said the woman will receive "the majority" of the sale money.

Dominique Le Coent of Acteon Auction House said the sale represented a "world record for a primitive, or a pre-1500 work."

"It's a painting that was unique, splendid and monumental. Cimabue was the father of the Renaissance, but this sale goes beyond all our dreams," Le Coent said.

DA VINCI MYSTERY: 'ABANDONED' ANGEL AND CHRIST DISCOVERED BENEATH MASTERPIECE

Art experts said the painting likely was part of a larger diptych that


public funds. What Ford rarely says is that his father was a millionaire businessman who sat in the Ontario legislature between 1995 and 1999 as part of the province’s Progressive Conservative Party, during a period of privatization, tax cuts and brutal cuts to social programs.

Ford has succeeded in Toronto's working-class neighborhoods by campaigning on issues that appeal to their needs (most notably his plan to extend the city’s subway to the far-flung suburbs). And the rest of Ford Nation, as Ford calls his supporters, is united in the almost fundamentalist belief that he will save them tax money.

Advertisement:

Part of Ford’s costume as an average guy is a readiness to admit that he likes to party — a cheery euphemism for his substance abuse problems. He likes to partytime already hired a former drug enforcer with a history of violent crimes to coach the team.

Advertisement:

Perhaps most famously, Ford used official City Council letterhead to solicit donations to his football charity from lobbyists registered with the city. Despite having been warned by the speaker that he was in a potential conflict of interest, he then voted against a city council motion to force him to pay back the money he received. In the court case that followed, Ford claimed he did not understand the meaning of “conflict of interest,” maintaining that he had never read the Municipal Conflict of Interest Act or the City of Toronto councillor orientation handbook, which described potential conflict-of-interest situations, and had never attended the City Council training sessions in which conflicts of


Q:

Extract indices of sublists found within a list

Given list_a and list_b. I want to run list_b through a function that gives all possible sublist of list_b (this part of the code works). I then want to take every sublist of list_b, and see if that sublist is also a sublist of list_a. If it is I should get a list of all the indexes, or splices where that sublist appears in list_a.
I'm able to get the code to work for sublist of length one, but cannot get it to work for longer lists.
Here's my current code to solve this problem:
import numpy as np

a = [0,1,2,3,0,2,3]
b = [0,2,3]

sublists = []
def all_sublists(my_list):
    """ make a list containg every sublist of a my_list"""
is because organic, non-paid advertising is possible if you have incredible content, which you should. People should be liking, sharing and commenting on your videos. In other words, your audience should be doing your job for you.

A large organic engagement rate can serve as the spark for the wildfire of subsequent ads, as you might want to boost the high-performers. However, your content should be good enough that you shouldn’t have to boost it.

When something goes viral, it’s not because somebody paid for it to do so. It’s because a large number of people positively reacted to it. That’s what you want to happen to your videos.

Facebook Live Is a Rising Star in Marketing

On Facebook, the only thing better than video is live video. Live video can bring


Q:

animation with matplotlib 'format "rgba" is not supported'

I'm trying to make an animation with matplotlib, using the examples from here.  At first the problem was ffmpeg wasn't installed, so I installed that from macports - but not it's saying that 'rgba' is not supported.  The error message:
File "Plot_shocktube1D.py", line 85, in <module>
    animDensity.save(densityAnimationName, extra_args=['-vcodec', 'libx264']) #, writer=movWriter)
  File "/opt/local/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages/matplotlib/animation.py", line 615, in save
    writer.grab_frame()
  File "/opt/local/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages/matplotlib/animation.py", line 199, in grab_frame
    dpi=self.dpi)
  File "/opt/local/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages/matplotlib/figure.py", line 1363, in savefig
    self.canvas.print_figure(*args, **kwargs)
  File "/opt/local/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages/matplotlib/backend_bases.py", line 2012, in print_figure
    print_method = self._get_print_method(format)
  File "/opt/local/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/site-packages/matplotlib/backend_bases.py", line 1953, in _get_print_method
    '%s.' % (format, ', '.join(formats)))
ValueError: Format "rgba" is nota usable m4v file:
import matplotlib.animation as animation
fig2 = plt.figure()

x = np.arange(-9, 10)
y = np.arange(-9, 10).reshape(-1, 1)
base = np.hypot(x, y)
ims = []
for add in np.arange(15):
    ims.append((plt.pcolor(x, y, base + add, norm=plt.Normalize(0, 30)),))

im_ani = animation.ArtistAnimation(fig2, ims, interval=50, repeat_delay=3000, blit=True)
im_ani.save('im.m4v', writer=animation.FFMpegFileWriter(), metadata={'artist':'Guido'})


Reperfusion reduces left ventricular dilatation by preventing infarct expansion in the acute and chronic phases of myocardial infarction.
Reperfusion reduces left ventricular dilatation in patients with acute myocardial infarction, but it is unclear to what extent this is a primary effect or only a consequence of the limiting effect of reperfusion on infarct size. To address this issue, 56 consecutive patients were examined by means of two-dimensional echocardiography on day 1, on day 3, before discharge, and at 6 months after an acute myocardial infarction. From this population two groups of 12 patients each, perfectly matched for site of myocardial infarction, extent of ventricular asynergy at two-dimensional echocardiography (akinesis + dyskinesis), and clinical characteristics were identified according to the creatine kinase (CK) time to peak, which was regarded asThe topic of OTA software updates for embedded devices is gaining attention as embedded systems are increasingly being connected. Highly publicized breaches continue to demonstrate the lack of security in the design of embedded systems. The software update process itself is intricate with many security considerations and it plays an urgent role in the security of the Internet of Things.

A good example is the Jeep Cherokee hack in July 2015. A couple components that allowed two security researchers to hack into the vehicle remotely were due to not having a secure over-the-air (OTA) solution. One of the first steps enabling this breach was a software vulnerability that was left unpatched in the multimedia system, which ran a Linux-based operating system. They exploited that vulnerability, which lead the security


Enhancement of transdermal drug delivery: chemical and physical approaches.
Transdermal drug delivery has been intensively studied over the last two decades because of the many advantages offered by this route of administration. However, the number of drugs used in transdermal drug delivery systems has been somewhat limited, in part resulting from the formidable barrier to drug permeation presented by the upper layer of the skin, the stratum corneum. In order to overcome this, different strategies have been implemented to render the skin more permeable to drugs. These strategies include both chemical and physical approaches. In this review, we outline the enhancing activities and mechanisms of action of some of the more extensively studied chemical penetration enhancers (oxazolidinones, propylene glycol, and epidermal enzymes). In addition, we discuss novel physical strategies,is CBP and the guest material is iridium bis[2-(2′-benzo[4,5-a]thienyl)pyridinate-N,C. sup.3′]acetylacetonate (Btp2Ir(acac)).
Kwong, in the periodical “Appl. Phys. Lett.” (Vol. 81, No. 1, 1 Jul. 2002, pp.162-164) discloses a phosphorescent organic light-emitting device having a hole-blocker layer, wherein, in the light-emission layer, the host material is CBP and the guest material is Ir(ppy)3.
In 1999, Forrest discloses in Appl. Phys. Lett. 74, 442 (1999), an organic phosphorescent material, “PtOEP”, doped in CBP by evaporation. In 2001, Forrest further discloses in Appl. Phys. Lett. 78, 1622 (2001), a red phosphorescent material containing iridium, “Btp2Ir(acac)”, doped in CBP.


Usefulness of albuminuria as a prognostic indicator in patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
Albuminuria is an established risk factor for mortality and cardiovascular events in the general population. Albuminuria might be a marker of the various pathophysiologic changes, such as diffuse vascular injury and systemic inflammation, that arise in patients with chronic heart failure (CHF). However, the relation between albuminuria and CHF has not yet been fully elucidated. Therefore, the purpose of the present study was to assess the prevalence and prognostic significance of albuminuria in patients with CHF secondary to ischemic or idiopathic dilated cardiomyopathy. Of the 712 patients with CHF, 311 had normoalbuminuria, 304 had microalbuminuria, and 97 had macroalbuminuria. The patients with albuminuria had more cardiovascular co-morbidity and worseLamaze Play & Grow Sophie the Princess now £5.97 del @ Amazon

rrp £10.99, excellent reviews across the net, Amazon have just price matched Tesco's offer on this baby toy, as usual amazons price inc home del whereas Tesco's is del to store (will pop link to there in 1st post). My girls had this lamaze toy & as with all lamaze baby toys it was fab quality & they loved it.Princess Sophie is plush and gorgeousHelps with visual stimulation and developmentClacking beads and crinkly skirtBold colours and contrast prints help with visual stimulation and developmentPerfect for baby's first dollRoyalty never looked (or felt) so good! Princess Sophie holds her jewels (clacking beads) in her hands for baby to play with and her skirt crinkles to keep baby's interest.


Uromyces ciceris-arietini, the Cause of Chickpea Rust: New Hosts in the Trifolieae, Fabaceae.
Uromyces ciceris-arietini has been reported on Cicer arietinum (chickpea) and Medicago polyceratia. Plants of Medicago polymorpha in Riverside and San Diego, CA were collected with severe rust caused by U. ciceris-arietini. To confirm the identification and potential new host range, a monouredinial isolate of U. ciceris-arietini from M. polymorpha was inoculated on eight accessions each of C. arietinum and M. polyceratia. All plants showed symptoms of the disease. Consequently, a range of fabaceous hosts were evaluated for their reaction to U. ciceris-arietini. New hosts for U. ciceris-arietini included 29 species of Medicago, specifically M. arabica, M. blancheana, M. ciliaris, M. constricta, M. coronata, M. doliata, M. granadensis, M. intertexta, M. italica, M. laciniata, M. lanigera, M.     // Helmholtz-PML options [also uses Fox-Li omega]
        const El::Int mx =
          El::Input("--mx","number of x points for HelmholtzPML",30);
        const El::Int my =
          El::Input("--my","number of y points for HelmholtzPML",30);
        const El::Int numPmlPoints =
          El::Input("--numPml","num PML points for Helm",5);
        const Real sigma = El::Input("--sigma","PML amplitude",Real(1.5));
        const Real pmlExp =
          El::Input("--pmlExp","PML takeoff exponent",Real(3));


             ( ACpx, mx, my, Scalar(omega), numPmlPoints, sigma, pmlExp );
                isReal = false;
                break;
        case 7: matName="TrefethenEmbree";
                El::TrefethenEmbree( ACpx, n );
                isReal = false;
                break;
        case 8:us for sure for two years and hopefully a little longer.

Sky F1's Simon Lazenby is put through his paces in the gym by Force India driver Esteban Ocon to see exactly how fit you need to be to drive a 2017 F1 car Sky F1's Simon Lazenby is put through his paces in the gym by Force India driver Esteban Ocon to see exactly how fit you need to be to drive a 2017 F1 car

"We were very fortunate to be able to have a look at him early on in his career. At that time he dealt very well with the engineers, showed his promise on track and we were very optimistic that we could get him later.

"He's fitted in exceptionally well. It's always very difficult for


wildlife than lawns:

https://butterfly-conservation.org/files/habitat-bracken-for-butterflies.pdf.

Fonseca's seed-fly, thought endemic to Sutherland dunes, requires 'weeds'. Claims about environmental net gain from moving fragile habitats & species, controlling Scots pine, rare & native at Coul, & cessation of duck shooting are ludicrous.

Threatened habitats outside the SSSI, in a golf 'remediation' area, are of comparable biodiversity, including Fonseca's seed-fly, rough horsetail, moonwort, skullcap, butterwort, fragrant, frog & creeping lady's-tresses orchids, small blue butterfly & plants at their northern UK limits, like restharrow & abundant rock-rose, the food-plant of dependent scarce northern brown argus butterfly.

The developers talk of 'sensitivity', 'minimalism', ‘naturalness’, 'utmost care' & the high repute of its designers, but experience in Oregon paints a different picture:

http://www.notcoul.com/developers.html

Leading dune ecologist Dr Tom Dargie describes the developer’s surveys & Environmental Statement as ‘unfit for purpose’. He        optInd++;
         seconds = argv[optInd];
      }
    } else if(strcmp(arg, "-R") == 0) {
      if ( optInd + 1 < argc ) {
         optInd++;
         millis = argv[optInd];
      }
    } else if(strcmp(arg, "-P") == 0) {
      if ( optInd + 1 < argc ) {
         optInd++;
         parse = argv[optInd];
      }


class="nav-group-task">
                Array

                CGSize

                UIView

                NodeDescriptionProps

                NodeDescriptionState

                NodeDescriptionWithChildren


above common genetic variants on amygdala volume, as determined using manual and automated (Freesurfer) parcellation protocols. The use of automated software packages to quantify amygdala volume is increasing with the availability of large databases of high-resolution magnetic resonance images (MRIs), and because of collaborative efforts such as the ENIGMA consortium (<http://enigma.loni.ucla.edu/>). Although direct comparisons between manual tracing and automated segmentation protocols show high overlap and significant positive correlation,^[@bib48]^ it is unclear whether manual and automated methods are equally sensitive to the small effect sizes of genetic influences on amygdala volume.

We hypothesized that amygdala volume would be increased in s allele carriers of the 5-HTTLPR polymorphism based upon previous findings of increased risk for mental illness and increased amygdala function and volume in s allele carriers. We predicted thatstructures such as the hippocampus. Appearing initially as gray matter above the temporal horn, the amygdala was bounded by a thin strip of white matter at its superior-lateral edge, separating it from the claustrum and the tail of the caudate; the angular bundle and entorhinal cortex bounded the amygdala medially; the semilunar gyrus defined the superior-medial boundary; and the hippocampus and the temporal white matter defined the inferior and inferior-lateral boundaries, respectively. The anterior boundary of the amygdala, which can be difficult to observe in MRI images, was defined as either the slice posterior to the appearance of the optic chiasm, or where the lateral sulcus closes to form the entorhinal sulcus, whichever was more posterior. Volumetric estimates were obtained by summing all voxels within the left and


right amygdalae within all traced slices.

To contrast against the results from the manual tracing protocol, we also computed amygdala volumes with the fully automated subcortical segmentation component of Freesurfer\'s (<http://surfer.nmr.mgh.harvard.edu/>) cortical reconstruction process, which has been shown to be more highly correlated with hand tracing than other automated protocols.^[@bib48]^ This also provided a measure of intracranial volume, which was used as a covariate in all analyses, because of the influence of intracranial volume on amygdala volumetric measurements.^[@bib55]^

Genotyping
----------

DNA was isolated from 2 ml saliva collected using Oragene self-collection kits (DNA Genotek, Kanata, Ontario, Canada). Primers for PCR amplification were designed using Primer3,^[@bib56]^ and are contained in [Table 1](#tbl1){ref-type="table"}. DNA was amplified using standardized procedures: PCR for rs22531 and STin2, and touchdown PCR for 5-HTTLPR and rs53576. PCR product was digestednetworking. A hypervisor owns those x86 servers and runs virtual machines (VMs) as their primary workload. The local storage in the servers is combined into a storage cluster that hosts the VMs. The storage cluster is software-defined. The storage cluster software might be part of the hypervisor, or it might run in a virtual storage appliance (VSA), which is a VM. An important part of being an HCI product is that the management of all these parts needs to be integrated: The magic happens in the software.

If you already have hardware, or if you want specific hardware, then hyper-converged software leaves the hardware choice to you. Some software-only HCI options are also available with your choice of hardware. If you always buy x86 servers from one vendor, you


variety of compounds, including peptide aldehydes,[@BIB13], [@BIB14], [@BIB15]peptide fluoromethyl ketones,[@BIB16]β-lactams,[@BIB17]isatins,[@BIB18]homophthalimides,[@BIB19]vinylogous esters and sulfones,[@BIB12], [@BIB20], [@BIB21]and halomethyl carbonyl compounds.[@BIB22], [@BIB23]Some of these compounds do show in vitro antiviral activity in cell culture,[@BIB12], [@BIB15], [@BIB16], [@BIB18], [@BIB19], [@BIB20], [@BIB21]but toxicity can be a problem for substances that are generally reactive with thiols.[@BIB18]

In the present study we examine a number of sulfur-containing azaglutamine derivatives as potential inhibitors of HAV 3C proteinase. Incorporation of hydrazino functionality into peptide backbones (azapeptides) is well-established for generation of proteinase inhibitors,[@BIB24], [@BIB25]including cysteine proteinases.[@BIB26]Recently such analogues have been shown to act as active site titrants for cysteine proteinase,[@BIB27]and certain symmetrical bis-hydrazides are extremely potent nanomolar inhibitors of cathepsin K, a cysteine proteinase involved in bone-remodeling.[@BIB28], [@BIB29]In one study on HRV 3C proteinase, an *N*-bromoacetyl azaglutamine dipeptide490.2001.

### 3.1.7. (3*S*)-{*N*^1^-\[3′-(*N,N*-Dimethylamino)-3′-oxopropyl\]-*N*^1^-(methyl-sulfonyl)}-1,3-diaminobutan-2-one hydrochloride (9)

To a solution of *N*-Cbz sulfonamide **7** (0.580 g, 1.40 mmol) in methanol-HCl (40 mL) under argon was added 10% palladium on charcoal catalyst (58 mg). The mixture was stirred under an atmosphere of hydrogen until gas absorption ceased. The catalyst was removed by filtration through a column of Celite, and the filtrate was concentrated in vacuo to give deprotected sulfonamide **9** (0.443 g, quantitative) as a glassy solid: IR (MeOH cast) 3440, 2921, 1737, 1619, 1325, 1145 cm^−1^; ^1^H NMR (300 MHz, CD~3~OD) δ 4.55 (d, 1H, *J*=19.3 Hz, CHH~A~), 4.41 (d, 1H, *J*=19.3 Hz, CH~B~H), 4.25 (q, 1H, *J*=7.2 Hz, CH), 3.53 (t, 2H, *J*=6.4 Hz, CH~2~), 3.01 (s, 3H, SO~2~CH~3~), 2.94 (s, 3H, NCH~3~), 2.87 (s, 3H, NCH~3~), 2.74 (d, 3H, *J*=6.4 Hz, COCH~2~), 1.53 (d, 3H, *J*=7.2 Hz, CH~3~); ^13^C NMR (75 MHz, CD~3~OD)


*J*=7.0 Hz, NCH~2~), 2.98 (s, 3H, NCH~3~), 2.89 (s, 3H, NCH~3~), 2.60 (t, 2H, *J*=7.0 Hz, COCH~2~), 1.42 (s, 9 H, (CH~3~)~3~C); ^13^C NMR (75 MHz, CDCl~3~) δ 170.54, 155.80, 79.62, 46.20, 36.60, 34.49, 30.99, 27.73; HRMS calcd for C~10~H~21~N~3~O~3~ 231.1583, found 231.1582.

### 3.1.15. 3-\[*N*^1^-(*tert*-Butyloxycarbonyl)-*N*^2^-(benzyloxycarbonyl)hydrazino\]-*N,N*-(dimethyl)propanamide (18)

To a suspension of Boc-propanamide **17** (2.31 g, 10 mmol) and anhydrous potassium carbonate (6.91 g, 50 mmol) in dry THF (20 mL), was added benzyl chloroformate (1.88 g, 11 mmol) with vigorous stirring. The mixture was heated to 40--50 °C for 2 h. The precipitate of KHCO~3~ and K~2~CO~3~ was removed by filtration. The filtrate was concentrated in vacuo. The residue was dissolved in ethyl acetate (100 mL), washed with 1 N NaHCO~3~ (20 mL), water (20 mL) and brine (20 mL), dried (Na~2~SO~4~) and concentrated in vacuo to give an oil. Purification by flash chromatography (ethyl acetate)gave **18** (3.2 g, 87%) as a colorless oil: IR (CH~2~Cl~2~ cast) 3251, 2976, 2934, 1741, 1709, 1632, 1497, 1400, 1366, 1257, 1209, 1159 cm^−1^; ^1^H NMR (360 MHz, CD~2~Cl~2~) δ 7.38--7.30 (m, 5H, ArH), 7.22--7.05 (brs, 1H, CONH), 5.14 (s, 2H, CH~2~O), 3.70 (t, 2H, *J*=6.7 Hz, NCH~2~), 2.96 (s, 3H, NCH~3~), 2.87 (s, 3H, NCH~3~), 2.61 (t, 2H, *J*=6.7 Hz, CH~2~CO), 1.40 (s, 9 H, C(CH~3~)~3~); ^13^C NMR (75 MHz, CD~2~Cl~2~) δ 171.33, 156.54, 155.11, 136.65, 128.84, 128.53, 128.38, 81.50, 67.60, 47.62, 37.36, 35.30, 31.99,28.27; MS (FAB) 366.0 (28) (MH^+^).

### 3.1.16. 3-\[*N*^1^-(Acetyl-[d]{.smallcaps}-alanyl)-*N*^2^-(benzyloxycarbonyl)hydrazino\]-*N,N*-(dimethyl)propanamide (19)

To a stirred solution of Boc derivative **18** (1.10 g, 3 mmol) in dry CH~2~Cl~2~ (10 mL) under argon, was added trifluoroacetic acid (10 mL). The solution was stirred at room temperature for 2 h and was then concentrated in vacuo. Toluene (10 mL) was added,


COUNTY EXECUTIVE DAY VETOES AMENDED 2019 BUDGET

PRESS RELEASE FROM OFFICE OF COUNTY EXECUTIVE – County Executive Ed Day used his line-item veto power to veto 95 of the Legislative Majority’s ill-advised amendments to the 2019 County Budget. As seen in the attached document, Veto Schedule 2019.

“The Majority’s amended budget would have been a return to the days of speculative revenue, over-estimating sales tax revenue and a refusal to modernize county government,” said County Executive Day. “In short, a budget like theirs could lead us back down the path of deficits and double-digit tax increases; a return to the sins of the past.”

The vetoes include Legislative amendments that:

Included $3.5 million in speculative revenue and appropriations to ostensibly fund employee contract settlements

County Executive Day proposed a $709 million spending plan    Outcome outcome;

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    "COL115" VARCHAR2(4000),
    "COL116" VARCHAR2(4000),
    "COL117" VARCHAR2(4000),
    "COL118" VARCHAR2(4000),
    "COL119" VARCHAR2(4000),
    "COL120" VARCHAR2(4000)
   );

Table has around 200 rows and all columns are having values up to 4000 chars.
Query Format:
select "COL1","COL2","COL3" ......."COL120" from SRC."TEST_SO_MANY_COLUMNS"

Code snippet:
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 res.setFetchSize(10000);
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Not getting any error while fetching the resultSet. The problem occurs while iterating over the result set:
int count = 0;
if (resultSet.next()) {
    count++ ;
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The above iteration works fine for first 10 rows but gives the below exception afterto an international crisis.

I have seen things you people would not believe: NATO bases on fire off the coast of Izmir...pic.twitter.com/jamX73nFt3 — Robin Monotti (@robinmonotti) July 24, 2016

Under the NATO nuclear weapons sharing program, Washington maintains its largest overseas nuclear arsenal in Turkey, consisting of up to 50 nuclear weapons, according to some estimates. The nukes however are stored at the base at Incirlik, and none are reportedly stored in Izmir.

İzmir buca'da saat 8 deki durum bu pic.twitter.com/csLIBNWxqX — Okan Parimli (@OkanParimli) July 24, 2016

It took more than seven hours of battling the flames using helicopters and an airplane to contain the blaze. However, it has not yet been fully subdued, several local papers announced.


sweet. So I reduced the amount of sugar in the cake by 1/2 cup (ie, 3/4 cups instead of 1 1/4 cups). Instead of 1/2 tsp kosher salt, I added 1/4 tsp regular salt and 1/4 tsp vanilla extract. The rest of the recipe was followed exactly like it was mentioned. I baked the cake in a deep 8" round pan for about 47 minutes. During baking the cake seemed to rise beautifully, but it was not forming a dome like the other cakes. I thought it might be beacuse of the caramel syrup in the cake batter. After cooling the cake appeared flat-topped and dense, so I knew what some of the other DBers talked about having a dense moist cake. Since it was hectic for meand couldnt redo the cake, I decided to stick with what I had.

I made the frosting exactly as specified in the recipe except for the amount of caramel syrup was reduced to 1 1/2 tbsp and heavy cream was about 4 tbsp. I found the frosting to be really deeelicious and to my taste!! I pretty much went simple with the decorations on the cake, with just some star flowers along the bottom border and rosettes along the top border. A few star flowers were piped on the top surface and dark chocolate chips were placed on the rosettes. My lil one was truly excited to see the entire frosting done before her eyes and when I declared that it was made specially for her, she was ecstatic!!


EC and Trupti

Thanks Trupti and Sireesha

Thanks Trupti and Sireesha!

Thanks Su and Ramya

Thanks Ramya

Thanks Ivy!

Humble beginnings!

I became a fan of cooking blogs when I came to the US because I suddenly found myself to be a home-maker with little knowledge of cooking and a lot of free time on my hands. After a couple of years and experimenting with a lot of food, I started thinking about my own blog!!! But doubting my writing skills, I have been pushing it back for some time. But with a bit of encouragement from one of my close friends and a boosting jolt from my husband, I decided not to wait any further. I hope that everybody will enjoy going through and trying out the recipes.

When I first started depending on theDocument Translation Services - Delhi

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  //   params  struct of optional parameters
      // Outputs:
      //   VV  #VV by 3 list of vertex positions
      //   FF  #FF by 3 list of triangle indices into VV
      //   IF  #intersecting face pairs by 2  list of intersecting face pairs,
      //     indexing F
      //   J  #FF list of indices into F denoting birth triangle
      //   IM  #VV list of indices into VV of unique vertices.
   In Undo the End, it's your mission to save the world. You have a device that allows you to visit the past, but only for a few seconds. Switch between the past and present to overcome the perils of a post-apocalyptic world. Reach the end of the game so that you can undo the end of the world!


the existence of a unique diverging length at the depinning threshold with an exponent $\nu= 1.04 \pm 0.04$, which controls the critical force distribution, the finite-size crossover force distribution and the intrinsic correlation length. Finally, a scaling relation is found between velocity and temperature with the $\beta$ and $\delta$ critical exponents both independent with regard to pinning strength and disorder realizations.'
address:
- '$^1$ GREMAN, UMR 7347, Université F. Rabelais, Parc de Grandmont, 37200 Tours, France'
- '$^2$ Department of Physics, Syracuse University, Syracuse, New York 13244, USA'
author:
- 'N Di Scala$^1$, E Olive$^1$, Y Lansac$^1$, Y Fily$^2$ and JC Soret$^1$'
title: Elastic depinning transition of vortex lattices in two dimensions
---

Introduction {#intro}
============

The physics of disordered elastic systems is relevant for numerous systems, [*e.g.*]{} interfaces like magnetic [@Lemerle1998] or ferroelectric [@Paruch2005] domain walls, contactacting on ${\bf r}_i$. ${\bf F}^L=F{\bf \hat x}$ is the Lorentz driving force in the $x$ direction induced by an applied current, and $\eta$ is the viscosity coefficient. The Langevin force ${\bf F}_i^{\text{th}}$ describes the coupling with a heat bath and can be expressed by a thermal gaussian white noise with zero mean and variance $$\langle F_{i,\lambda}^{\text{th}}(t) F_{j,\mu}^{\text{th}}(t') \rangle=2 \eta k_B T \delta_{ij} \delta_{\lambda \mu} \delta (t-t')$$ where $\lambda, \mu=x,y$ are the cartesian components of ${\bf F}_i^{\text{th}}$ and $k_B$ is the Boltzmann constant. The vortex-vortex pairwise repulsive interaction is given by a modified Bessel function $$U^{vv}(r_{ij})=\alpha_v K_0(r_{ij}/\lambda_L)$$ and the attractive pinning potential is given by $$U^{vp}(r_{ip})=-{\alpha_p} e^{-(r_{ip}/R_p)^2}$$ where $R_p$ the radius of the pins, and $\alpha_v$ and $\alpha_p$ are tunable parameters. We fix the strength of the vortex-vortex


critical depinning force indicates a crossover from elastic dynamics dominated by elasticity to plastic dynamics dominated by disorder: such a sharp increase was for example found in a previous work on a similar system [@Reichhardt2002]. In Fig. \[Fig1\]b the typical trajectories of the vortices at the elastic depinning threshold are displayed for $\alpha_p/\alpha_v \approx 5.10^{-3}$. The vortices flow in elastically coupled rough static channels and the structure is topologically ordered: all vortices depin together with the same mean velocity, which means that all vortices keep the same neighbors as they move. The dynamics is jerky and the velocity of the center of mass is periodic in time where the period corresponds to the time for each vortex to replace its preceding neighbor in the same channel.\

Velocity-force response {#v-f}
-----------------------

For eachvelocity-force response a) versus $L_y$ for $L_x=100\lambda_L$. Averages are computed over $N=(9, 7, 4, 21, 4)$ samples for respectively $L_y=(2, 7, 18, 50, 120) \sqrt3/2 \lambda_L$ b) versus $L_x$ for various transverse sizes from $L_y=18 \sqrt3/2\lambda_L$ to $L_y=120 \sqrt3/2\lambda_L$. Averages are computed over $N=(44, 47, 39, 12, 27)$ samples for respectively $L_x=(15, 40, 100, 200, 400)\lambda_L$. The error bars correspond to the standard error associated to the value of $\beta$ extracted from the fit.[]{data-label="Fig3"}](Fig3a "fig:"){width="40.00000%"} ![\[Fig3\] Depinning exponent $\beta$ extracted from a power law fit in region II of the disorder averaged velocity-force response a) versus $L_y$ for $L_x=100\lambda_L$. Averages are computed over $N=(9, 7, 4, 21, 4)$ samples for respectively $L_y=(2, 7, 18, 50, 120) \sqrt3/2 \lambda_L$ b) versus $L_x$ for various transverse sizes from $L_y=18 \sqrt3/2\lambda_L$


the functional form $<v_x(0)v_x(x)> \sim C_0 x^{-\kappa} e^{-x/\xi}$ (see [@Duemmer2005]). We find that both fit parameters $C_0$ and $\kappa$ are almost constant when $F-F_c^{\infty}$ varies. For a given disorder realization and $(L_x,L_y)=(100, 18 \sqrt3/2) \lambda_L$, Fig. \[Fig6\] shows the evolution of $\xi$ as a function of $F-F_c^{\infty}$.

![\[Fig6\] Plot of $\xi$ versus $F-F_c^{\infty}$ for a given disorder realization and for a system size $(L_x,L_y)=(100, 18 \sqrt3/2) \lambda_L$ at $\alpha_p/\alpha_v \approx 5.10^{-3}$. The error bars indicate the standard error associated to the value of $\xi$ extracted from the fit $<v_x(0)v_x(x)> \sim C_0 x^{-\kappa} e^{-x/\xi}$. The black arrow indicates the value of $F_{\text{cross}} - F_c^{\infty}$.[]{data-label="Fig6"}](Fig6){width="47.00000%"}

As expected, when $F \rightarrow F_{\text{cross}}^+$ finite size effects actually appear when $\xi \sim L_x$ with $L_x=100\lambda_L$. Furthermore the correlation length $\xi$ diverges as $\xi \sim (F-F_c^{\infty})^{-\nu}$ forand $T_0$ are not universal and their value varies for each sample, but the scaling functions $S_{\pm}$ remain unchanged. We verified that averaging over disorder as previously defined, we obtain the same scaling functions.\
The collapse of our data implies that a true critical regime is observed with power law responses for the velocity with respect to the driving force and to the temperature. Moreover the critical depinning exponent $\beta$ and the thermal exponent $\delta^{-1}$ do not depend on the strength and the positions of the pins. Theses results suggest some degree of universality of our model for the elastic depinning of vortices.

Discussion {#discuss}
==========

In our study we find a continuous elastic depinning transition for weak pinning strength. Both the depinning exponent $\beta$ and the thermal exponent $\delta$, and the


---
abstract: 'Double-lined spectroscopic binaries (SB2s) are one of the main sources of stellar masses, as additional observations are only needed to give the inclinations of the orbital planes in order to obtain the individual masses of the components. For this reason, we are observing a selection of SB2s using the SOPHIE spectrograph at the Haute-Provence observatory in order to precisely determine their orbital elements. Our objective is to finally obtain masses with an accuracy of the order of one percent by combining our radial velocity (RV) measurements and the astrometric measurements that will come from the [*Gaia*]{} satellite. We present here the RVs and the re-determined orbits of 10 SB2s. In order to verify the masses we will derive from [*Gaia*]{}, we obtained interferometric measurements of the ESO[e.g. @Lebreton05].

It is only possible to obtain a mass for a few very specific stars, but these are the basis of calibration relationships that allow the masses of other stars to be estimated from more accessible data, such as spectral type, color indices or absolute luminosity [e.g. @Eker15; @Moya18; @Mann19]. These calibrations paved the way for population synthesis models, ultimately allowing to estimate the stellar mass-to-light ratios of galaxies from their observed colours or spectral energy distributions [e.g. @Bell01], which are central to the estimate of their dark matter content [e.g. @Lelli16].

There are only a limited number of direct methods for measuring the mass of a star, and they all apply to components of double stars. Most (but not all) use the double-lined spectroscopic binaries (SB2s), for which


in Section \[sect:interfero\], where we briefly discuss the evolutionary state of these stars and their positions in the HR diagram. Section \[sect:conclusion\] is the conclusion.

Observations {#sect:observations}
============

Spectroscopic observations {#sect:observationsSpectro}
--------------------------

As before, the observations were performed at the T193 telescope of the Haute-Provence Observatory, with the SOPHIE spectrograph. From 2010 to 2016, they were carried out in visitor mode by assigning priorities to the stars based on ephemerides. Since semester 2014B, we have regularly obtained observations in service mode that we request for selected dates in order to complete phase coverage while avoiding blends that would give unusable RV measurements. Exceptions to this rule are generally stars for which the preliminary orbit was inaccurate, or stars suspected for a time of being multiple systems.

The list of stars treated in this article is givenby interferometry {#sect:interfero}
==============================================================

Calculation method {#sect:correctionBV}
------------------

Of the ten SB2s, five were sufficiently observed by interferometry to calculate a combined orbit giving the masses of the components and the trigonometric parallax of the system. However, before combining RVs and interferometric measurements, uncertainties must first be corrected. This has been done for the RVs in Section \[sect:SB2orbits\], but remains to be done for interferometric measurements. The method is similar to that applied to RV uncertainties in Section \[sect:SB2orbits\]: The visual orbit is calculated and the $\chi^2$ is considered. From this we deduce the corrective coefficient that must be applied to the uncertainties for $F_2=0$. After this correction, the combined spectroscopic and interferometric orbit is derived from the RVs and from the relative positions. The solutions terms are $P$, $T_0$, $e$, $V_0$, $\omega_1$, and


they are more reliable, due to the better quality and homogeneity of the RVs.

The parallax is 3.7 $\sigma$ larger than that found in the [*Gaia*]{} DR2, which is $(8.215 \pm 0.044)$ mas.

Hertzsprung-Russell diagram and mass-luminosity relation {#sect:diagHR-ML}
--------------------------------------------------------

Figure \[fig:diagHR\] shows the location in the Hertzsprung-Russell (hereafter HR) diagram of the ten stars in the five SB2 systems for which we have inferred the individual masses, while Figure \[fig:ML\] shows their position in the mass-luminosity plane.

To draw these figures, we started from the effective temperatures, metallicities, and surface gravities given in Table \[tab:stellpar\]. We corrected the metallicity by adding $+0.12$ to each \[Fe/H\]-value to account for the fact that in our study the solar spectrum is adjusted with $\mathrm{[Fe/H]}_\odot = -0.12$ (as specified in the table caption). Following the conservative guidelines given in theis smaller by more than 600 K than the value derived by @Casagrande11 by photometric calibration ($T_\mathrm{eff, A}$ = 6853 $\pm$ 80 K), while @Casagrande11’s metallicity (\[Fe/H\]= $0.11\pm 0.10$) is higher than our corrected value, although still within the error bars. If we take @Casagrande11’s metallicity as a robust value and optimize again, we get $T_\text{eff,A}$=7200$\pm$30K, $T_\text{eff,B}$=7150$\pm$70K, $\log g_A$=3.8$\pm$0.2, $\log g_B$=4.1$\pm$0.2. In the following, we adopt these latter sets of parameters for the two couples.

To derive the individual luminosities, we proceeded in two steps. We first derived the individual apparent magnitudes from the magnitude difference between the components of HIP 20601, HIP 96656, HIP 104987, and HIP 117186 measured in the $H$-band by PIONIER. For HIP 77725, we used the magnitude difference in infrared measured by @Horch17 with the


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As described in the official site, SEBE (Solar Energy on Building Envelopes):

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my mind, it was great,” he says. “It was like a feeling I’ve never felt, and it was almost like, ‘I’m home.’”

Sean spent the next 12 years chasing that feeling, cycling between using, jail, and attempts at recovery. He got clean during a five-year stint in prison, but when he was released in 2015, he found the old cravings coming back.

“The mental is constantly there,” he says. “Just knowing that heroin is within a mile radius anywhere I go in Philadelphia.”

Shortly after a major relapse, Sean remembered something he’d heard a few years before — about an herbal supplement called kratom that was supposed to ease withdrawal symptoms and tamp down cravings. After doing some research online, he decided it was worth a try, and picked some upof groups dedicated to the supplement, some with memberships exceeding 13,000. Reddit’s official kratom group has more than 43,000 members.

As the number of kratom users has grown, so have the claims about its therapeutic potential. Converts tout it as an effective alternative treatment for chronic pain and opioid withdrawal.

Darshan Singh, a researcher at the University of Science Malaysia’s Centre for Drug Research, has studied kratom for nearly 10 years, and says his work has convinced him of its potential.

“This is the cure for opioids,” he says. “If a scientist can actually prove that it’s a safer alternative, let me tell you, all the big pharmaceutical companies will be shutting down, because we could sell it 80 times cheaper than classical opioids, with far less detrimental effects.”

The federal government


says the group is working on a plan to establish safety standards governing quality and purity, along with a tracking system to help consumers trace any bad kratom batches back to their source.

“We’re not opposed to regulation,” he says. “We’re opposed to this demonization that wants to ban a product that doesn’t deserve to be banned.”

Scientists have also lobbied against the ban — both for the sake of research, and for users.

“Once that is done, we are putting a research kind of on the back burner because it limits access for research,” pharmacologist Oliver Grundmann says. “And I fear, together with a number of other scientists, that that will drive those who are currently using kratom back to opioids.”brush of intolerance as indelibly as Africa is with that of ethnic warfare.

Those countries that receive rebukes from the UN over human rights – as you can see from the list of those warned before the US – don’t tend to be ones that developed problems overnight. What the Trump era is graphically exposing is that America’s very public meltdown is an unravelling of issues that were suppressed, deflected or denied for many years. This didn’t all happen in the eight months since Trump became president. The pertinent fact here is that it took only eight months.

It took only eight months to go from a nation that voted for a black president two terms in a row to one that is suffering from race riots and killings, with


     3D Slicing                     [@pone.0051925-Henderson1], [@pone.0051925-Brochu1]

Note that just 77 dinosaur species were identified in the literature with combined femur length and body mass estimates. Maximum femur lengths from a total of 329 species were used in the exploration of dinosaur body size distributions and these data are available on request from the authors.

Note that *Anatosaurus copei* is now identified as *Edmontosaurus annectens* and *Brachiosaurus brancai* is now known as *Giraffatitan brancai*. In this table, we report the species names as listed in the original referenced publication for ease of cross referencing. This includes a number of dinosaur genera that do not contain species names inthe original paper.

All bird data were extracted from Dunning's 2008 handbook of avian body masses [@pone.0051925-Dunning1]. We chose to take the maximum body mass listed for each species, irrespective of the sex of the bird. These measurements constitute 9,381 out of approximately 10,000 bird species (94% completeness).

Reptile data were collated from a number of sources. Snout-vent lengths (SVL) for 4,874 lizard species were taken from Shai Meiri's dataset [@pone.0051925-Meiri1]. Here, maximum SVL is seen as a good measure of the size potential in a population and is tightly correlated with mean adult SVL and SVL at sexual maturity [@pone.0051925-Meiri1], [@pone.0051925-Greer1]. Lizard body masses were obtained using the SVL-mass allometries listed in [Table 2](#pone-0051925-t002){ref-type="table"} of Meiri's 2010 publication [@pone.0051925-Meiri2]. Body mass data for a further 1,330 reptile species were


all chiropterans, cetaceans, sirenians and pinnipeds were excluded from this dataset.

Frequency distributions of maximum species body size were plotted from these data for each group, with size bins of 0.2 width on a log~10~ scale. A combination of kernel density estimation and smoothed bootstrap resampling (based on 1000 randomisations) was used to examine the modality of these body size distributions. This procedure (described in detail in [@pone.0051925-Manly1], [@pone.0051925-Silverman1]) tests whether a distribution with *k+1* modes fits significantly better than a distribution with *k* modes, thus determining the optimum modality of the data. Other arbitrary techniques (e.g. [@pone.0051925-Holling1]) typically overestimate the number of modes and gaps in body size distributions [@pone.0051925-Manly1], [@pone.0051925-Siemann1]. The location of each mode was recorded relative to the *x*-axis. A measure of skewness was alsovertebrate groups. The body size distribution of extant and Cenozoic mammals were also compared using the Kolmogorov-Smirnov test.

To evaluate the consistency of observed patterns in the body size distribution of dinosaurs, the data were reanalysed after sub-dividing by clades, time periods and formations. Three major clades were employed in this analysis: Ornithischia, Sauropodomorpha and Theropoda, with 143, 86 and 100 data points, respectively. Six time periods were used: Late Triassic, Early, Middle and Late Jurassic, and Early and Late Cretaceous which used 23, 21, 31, 58, 61 and 135 data points, respectively. Finally, two major rock formations also had a sufficient number of species to be utilised: the Late Jurassic Morrison Formation in the western United States of America and the Late Cretaceous Dinosaur Park Formation in Alberta,


to match that of the extinct mammals, we would have to be missing around 90% of the non-avian dinosaurian diversity and all of it small (i.e. under 60 kg). To get our dinosaur distribution to match that of the extant mammals or birds, we would have to be missing 99.99% of diversity. Thus, we consider it implausible that taphonomic bias can be the sole force driving these results. Moreover, the pterosaurs (sister-taxon to the dinosauromorphs, living alongside them in the same environment and subject to similar conditions and taphonomic biases) display a more 'typical' vertebrate distribution in their body size (see [Fig. 2*g*](#pone-0051925-g002){ref-type="fig"}), suggesting the dinosaurian signal is genuinely unique.

If the evolution of large body size was a product of long exposure to a stable environment, we wouldthe smaller sauropodomorphs in size. Burness *et al*. [@pone.0051925-Burness1] showed that the body masses of the largest sauropods and theropods exceeded that predicted by the area of the land they occupied, yet no ornithischians were analysed as part of this work and at least some of these would similarly exceed the expected values. Thus, while Sander *et al*. [@pone.0051925-Sander1] make a convincing case for the uniqueness of the sauropods with respect to their great size, a number of their supposedly unique features were also present in the ornithischians and may have similarly affected this clade. Both include species that grew through five orders of magnitude, from a few kilos to over ten tons. Sauropodomorphs and ornithischians also had similar reproductive strategies, with both capable of laying 20 or


on the basis of the proportionate total assets of the company by the use of a so-called "allocation formula," which we will attempt to thus briefly describe: The department determined from the records of the corporation the total assets of the corporation to be $1,775,026,769.03. From these total assets there was deducted the "total amount of all liabilities except capital," as shown by the records of the company, to produce a capital figure of $182,376,634.27; this total capital figure was divided into two parts, the physical property used in the business amounting to $13,310,454.51 and the "other capital" amounting to $169,066,179.76; the physical property used in the business was allocated to Alabama upon a so-called situs basis, producing for the state $1050.68; Alabama's part of the "other capital"on the corporation on account of its property within a state, and may take the form of a tax for the privilege of exercising its franchises within the state, if the ascertainment of the amount is made dependent in fact on the value of its property situated within the state, the exaction, therefor, not being susceptible of exceeding the sum which might be leviable thereon, and if payment be not made a condition precedent to the right to carry on the business, but its enforcement left to the ordinary means devised for the collection of taxes." Postal Telegraph Co. Cable v. Adams, supra.
We think it manifest the italicized portions evinced the opinion of our court as then constituted that the actual amount of capital employed in the state


disease. In this review, we consider the association of PT activity with three different (but possibly related) aspects of pertussis disease: Severe disease in young infants; immune and inflammatory responses; and paroxysmal cough.

2. Role of PT in Severe Infant Pertussis {#sec2-toxins-11-00373}
========================================

In 1984, the contribution of PT to *B. pertussis*-induced lethality was first described \[[@B3-toxins-11-00373]\]. Using an infant mouse pertussis model, it was found that a mutant strain of *B. pertussis,* deficient in PT secretion, had a significantly higher LD~50~ than the parental wild type strain \[[@B3-toxins-11-00373]\]. This result was later confirmed, with that same mutant requiring a higher challenge dose to achieve 100% lethality \[[@B4-toxins-11-00373]\], without displaying impaired colonization \[[@B5-toxins-11-00373]\]. However, the mechanism by which PT promoted lethality in these studies was not examined.

In humans, the most severeor candidate attenuated vaccine \[[@B97-toxins-11-00373]\] strains, with no cough symptoms elicited. Since we cannot experimentally infect humans with isogenic wild type and PT-deficient *B. pertussis* strains to assess cough symptomology, evidence from humans indicating a role for PT in pertussis cough is more indirect. For example, an association between naturally occurring PT-deficient *B. pertussis* strains and reduced severity of cough symptoms in human pertussis cases would support a role for PT, but such strains are extremely rare and have only been reported in the published literature twice \[[@B32-toxins-11-00373],[@B33-toxins-11-00373]\], as mentioned in [Section 2](#sec2-toxins-11-00373){ref-type="sec"}. However, in neither case were the characteristics of cough reported. In addition, serology was not performed to assess the presence of anti-PT antibodies in the infected individuals and so it is impossible to know whether


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     nail polish that just needs more storage!

I have one 3-drawer container that holds most of my makeup. Top drawer is eye stuff: pigments, glitters, quads, and some single eyeshadows that I haven’t depotted. Middle drawer is all my lip stuff. Bottom drawer is face stuff. Sitting on top of that container I have a case that holds all my eyeshadow palettes. Then I have two boxes: one for cream shadows and color bases and gel liners and such, and the other for eyeliner pencils and mascaras and brow stuff.

I have 2 single carts and 2 double carts that hold all my non used products. Each drawer has plastic containers that hold each type of beauty product (lips, eyes, face etc). I sub-group from there (ie lip: gloss, liner,


with decorative beans from a craft store and a cd holder to arrange palletes. Sounds weird, looks nice, works really well!

i have 2 ikea alex 6 drawer units. one of them is filled with makeup.
i group them into categories : single eyeshadows\pigments, small palettes of shadows, cheeks\blush\bronzer\highlighter, foundation\concealer\powder, lipsticks\lipgloss, nails
i like this idea because it makes me see my entire stash and not only using the newest products.
also, i think it saves me money to be able to see everything and knowing what i have.
the lipsticks drawer i’m trying to find a way of making them stand in order for me to see the labels clearly
and i also use empty lip palettes and put about a third of all my lipsticks into it. (japonesque lip \ foundation palette)
ia good predictor of falls \[[@pone.0201035.ref014]\]. To the best of our knowledge, no previous studies have use this test in CKD populations.

Finally, the TUG test is a simple and valid method for assessing patients' levels of functional mobility \[[@pone.0201035.ref015]\]; it measures the time taken for an individual to stand up from a chair, walk three meters, turn, walk back, and sit back down. The TUG test has been used for different chronic diseases such as Alzheimer, chronic heart failure, or chronic obstructive pulmonary disease \[[@pone.0201035.ref016]--[@pone.0201035.ref018]\]. It has also been used in CKD patients undergoing HD \[[@pone.0201035.ref019]--[@pone.0201035.ref022]\] but neither its relative and absolute reliability nor its MDC have been previously calculated.

Aims and hypothesis {#sec002}
-------------------

The aim of this study was to calculate the test--retest reliability of the SPPB, OLST, and


allowed to wear their regular footwear and to use a walking aid if needed. A stopwatch was started on the word "go" and stopped when the subject was fully seated with their back against the backrest. The time to complete the test was recorded in three consecutive trials, using the first one to familiarize the subjects with the test. The best time from the three trials was analyzed \[[@pone.0201035.ref025],[@pone.0201035.ref028],[@pone.0201035.ref029]\].

### Human activity profile {#sec010}

To evaluate the physical activity level, the participants were asked to complete the Human Activity Profile (HAP) that has been validated in the population with renal disease \[[@pone.0201035.ref030]\]. The HAP questionnaire consists of a list of 94 items, which assesses activities ranked in ascending order of level of energy. The participants had three possibilities to answer:(1) still doing this activity, (2) have stopped doing this activity, or (3) never did this activity. The HAP assesses the Maximal activity score level of activity (MAS) (the highest level of activity) and the adjusted activity score (ASS). The MAS is calculated as the activity with the highest oxygen consumption requirement that the subject still performs, while the ASS = MAS---number of less demanding activities the subject has stopped performing. The ASS gives us a better estimate of the range activities performed and of the presence of impairment. Depending on the AAS, subjects can be classified as impaired activity (AAS less than 53), moderately active (AAS 53--74) or active (AAS greater than 74) \[[@pone.0201035.ref031]\]. This questionnaire has been shown to be test-retest reliability in this population, being


assess the effectiveness of interventions to maintain or improve the physical performance of patients receiving HD treatment.

Supporting information {#sec018}
======================

###### Original data from SPPB.

(XLSX)

######

Click here for additional data file.

###### Original data from OLST.

(XLSX)

######

Click here for additional data file.

###### Original data from TUG.

(XLSX)

######

Click here for additional data file.

The authors would like to acknowledge and thank all the individuals who contributed to this study, especially the participants, doctors, and nursing staff at the HD units where data were collected. We would also like to thank Alejandro Sendín and Vicent Benavent for their assistance in the data collection, as well as the Department of Physiotherapy at the Universidad CEU Cardenal Herrera, who provided us with considerable support and valuable contributions to this manuscript.

[^1]: **Competing Interests:**The authors have declared thatimportant to take the time that is needed. There could be action and a lot of adventure in the second act, but do not over do it. The second act is not about dazzling the audience right and left, it’s about a journey inside the human soul. The second act is preparing both the protagonist and the audience for the climax of the picture.

The transition between the second and third act usually comes on a low note rather then a high one. It is the calm before the storm. Do not clutter the end of your movie with too much action. Let your audience experience a low so the high is more impacting. Give the climax room to breath. The third act is where the main character either