monsoon, Delhi receives the air mass from the Arabian sea as well as from the east part of IGP. For Mumbai, most of the air masses originate from the nearby Arabian sea during monsoon, post-monsoon, and summer season. The contribution from the central Indian region during winter (55%) and post-monsoon (47%) are significant. Mumbai also gets transboundary air pollutants during winter and summer from countries located in the Middle-East region. For Kolkata, the IGP region is the major source of air masses during winter (81%) and post-monsoon (39%), and during the summer air masses originated from the land (IGP and central India) as well as from the Bay of Bengal. Moreover, during monsoon season the trajectory follows south-west monsoon wind pattern therefore the air masses originate from thethe traffic exposure ([@bb0580]) in urban areas.

We propose that the reduction in PM~2.5~ levels across the cities is due to the recent measures taken to reduce the ambient pollution levels in India. The major recent initiatives that might have helped in the reduction include the launch of the National Air Quality Index (AQI) for public awareness, the formation of Environment pollution (prevention and control) authority, implementation of a Graded Response Action Plan (GRAP) and Comprehensive Action Plan (CAP) for prevention, control and mitigation of air pollution in Delhi and NCR. National Clean Air Program (NCAP) was launched in January 2019 with comprehensive mitigative actions along with augmentation of the air quality monitoring network across the country. A tentative national target of 20--30% reduction of PM~2.5~ and PM~10~ concentration


from April 2017 and BS-VI was scheduled from April 2020. The old fleet scrappage program was launched, and electric vehicles are being promoted. Apart from this, shifting to alternate cleaner fuels like CNG, ethanol blending in petrol are some of the steps taken for the cleaner transport sector. Moreover, the use of a modern public transport system was promoted in recent years to reduce traffic emissions. While these measures reduce the exhaust emissions, the maximum reduction is expected in road dust resuspension emission ([@bb0575], [@bb0580]) by regular road dust cleaning by mechanized vacuum dust cleaners ([@bb0190]; [@bb0195]). Other measures include dust control from the building and road construction activities. The stringent measures to limit the crop residue burning. ([@bb0355]; [@bb0500]; [@bb0055]) and revised standards for coal-based thermal powerblurring). In logistic regression analysis, syncope was significantly associated with Tumarkin attacks (odds ratio 3.2), migraines (odds ratio 2.3) and nausea (odds ratio 1.3). The attack of syncope was experienced as frightening, and general health related quality of life (HRQoL) was significantly worsened. Also, the patients suffered more from fatigue. The current study indicates that patients with MD who suffer from Tumarkin attacks can suffer from syncope. It confirms the role of the otolith organ in controlling the circulatory homeostasis of the body. The actions are mediated through the vestibular sympathetic reflex.


improved from baseline for dogs fed the test food. Results suggested that feeding overweight dogs the test food caused weight loss and improvements in body condition during the weight-maintenance phase, possibly because the food composition improved energy metabolism.will begin soon after the entry period concludes and will last for one week. Voters will choose their favorite photo from each category (one vote per category).

The Coaster101 team will select 10 photos entered in the “Instagram” category to be posted on our Instagram page, where additional votes can be earned for each “like” the photo receives. Instagram entries can also earn votes on the website.

UPDATE: Voting is now open and will run through Saturday, July 29, 2017.

Winners

There will be two winners for the original and edited categories: one determined by readers’ votes and the other selected by the Coaster101 team. The Instagram category will have one winner as voted on by readers.

Winners will receive a Coaster101 prize pack including prizes from parks across the country, a print


Why we need epidemiologic studies of polycystic ovary syndrome in Africa.
The primary objective of the Ghana Polycystic Ovary Syndrome Epidemiology and Phenotype (Ghana-PEP) study will be to assess the relevance and phenotypic distribution of polycystic ovarian syndrome (PCOS) in a medically unbiased population of reproductive-aged women. In addition, the study will also attempt to identify sociodemographic, environmental, and psychological factors that may play a role in the development of PCOS phenotype. The study aims to recruit 990 randomly selected women aged 18-45 years living in Nsawam, the district capital of the Nsawam-Adoagyiri Municipality, in the Eastern region of Ghana. Participants will complete a questionnaire with the aid of trained personnel, undergo a physical examination, and undergo ultrasonography and biochemical evaluations relevant to PCOS. It is anticipated that themany voices and perspectives. It’s not unlike making a new craft, something that draws upon your skills and takes them to the next level. When I mastered a cabled sweater, I was jazzed. When I used a torch to fuse silver, I felt a thrill down my spine. And when I write something that resonates with me, I am creatively sated…at least for the moment.

But there’s a lot of bad writing and bad crafting in my world. It got me to thinking about the crafty stuff that I want to punch in the face, the things that send me over the edge…at least for the moment.

Here are my top ten craft things I want to punch in the face. I hope you’ll add to the list.

10. Lack of


last seam before I run out of thread in the bobbin. I am always wrong.

4. Beads that aren’t drilled properly. I’ve learned my lesson, but I have bought a lot of semiprecious gems that weren’t drilled through or drilled straight. I couldn’t get cord or silver wire through the hole. These days, I always try to feed SoftFlex or 26-gauge wire through before buying.3. Disappearing tools. I’ve loaned out a torch or pliers or a Dremel tool for a friend’s project, never see it again.

2. Multiplying materials. On the flip side, I often duplicate tools and materials when I’m out and about. I forget what size knitting needles I have at home when gathering materials for a new project at the yarn shop. I buy beads I’m prettyand ask,
"Do you sell your work?"
It's that or some attempt to convince you that you're work quality is marketable. I've never been able to find a dodge for that question, and my diplomatic answer, "Sometimes" just doesn't placate their type.
I feel like asking them what they'd charge per hour, for a project of this length. Let them alone to figure it out for a while. When their expression changes to one of enlightened shock, see if they're open to changing the conversation topic!
Posted: 2:23 pm on June 15th

DamarisA writes: When you get people who think that the price that you give them for a certain project that they want you to make is too pricey. Then they go and buy it from another person triple the price. Those


can come up with
Posted: 7:20 pm on April 6th

ksun writes: I want to punch lack of storage space in the face, and also items with multiple uses...what category should I store it in? ore worse: what category did I store it in.

I will invest in a great sewing machine so I dont have to punch tension in the face, but not proper shelving! go figure.

And to dgoddess about your mural: The jokes on your friends sister, who obviously doesn't have the class to know what she's missing. Every time you walk into your nursery you can say "this is awesome, and I have the good sense to know it!".

I try not to forget that we do these things for ourselves not for approval from others.

Happy crafting!
Posted: 6:25 pm(like cardboard or aluminum foil) and the worst thing yet.... people telling me that they can buy the same thing at Wal-Mart or Target and not have to "mess with doing it themselves". ARE YOU KIDDING ME?!?! See if they get a HAND quilted baby blanket or HAND crocheted sweater from me ever again!!!!

Posted: 5:53 pm on March 28th

QittCatt writes: Things about crafting that I want to punch in the face:
-Needle threaders that just don't work.
-Fabric that frays, even when you think it won't.
-When your sewing machine decides the fabic is too thick and refuses to sew.
-Having too many ideas and not enough time!
-And definately when people ask you to make things so they can buy them and then when you do, they don't..... argh!
Posted: 4:41 pm on


make projects that rely heavily on proper gauge or have complicated co-dependent pattern repeats, because I will inevitably mess it up, and despise going back. Many a project I have left as is, and convinced myself that they're reminders of 'Don't Do This Again' on the other sock or glove or somesuch.

I'm also with dgoddess on the wall muraling. I'm an artist, so I constantly get request from friends of 'well can you paint this on my wall?' Because they definitely don't understand how much time and work and money it takes to paint a mural.
Posted: 2:33 pm on March 25th

MizzKodak writes: The thing I hate the most is lack of space and ungrateful people. I spend a lot of time making things they asked me to andboth connected to a digital type electronic device.
As a practically useful method for inhibiting a radiant noise in an electric cable, it has been suggested that the electric cable be inserted into and through an elongated tubular magnetic member, or alternatively, an electric cable be passed through several ring-shaped core type magnetic members. With the use of the above methods, a common mode noise will be induced in an electric cable. The magnetic member causes an inductance in the electric cable. The inductance and a frequency component of the common mode noise generate an impedance. The impedance can inhibit the above described radiant noise.
FIG. 12 is a perspective view schematically illustrating an arrangement for inhibiting a radiant noise in an electric cable, which has been disclosed in Japanese


the two half case pieces are closed together, two longitudinal edge portions of the two-layer sheet-like magnetic structure covering the flat cable are firmly pressed by the two half case pieces of the flat case, thereby forming a closed magnetic circuit around the flat cable.
Moreover, the radiant noise inhibiting assembly of preferred embodiments of the present invention may be such that the flexible magnetic structure is made of a magnetic rubber obtained by mixing and kneading a desired amount of magnetic particles into a rubber.
Further, the radiant noise inhibiting assembly of preferred embodiments of the present invention may be such that the substantially cylindrical case is preferably made of a metal so that the substantially cylindrical case itself can serve as an electrically conductive structure, or the substantiallytwo-year stint during a “historically difficult” time in relations between the two countries.

It comes after reports that Trump and Putin discussed the need for a new US ambassador in Russia while speaking on the phone last week.


where people from designated countries, designated by the authorities, are not allowed to come freely? The Latin American Studies Association years ago began to have conferences elsewhere because of the restrictions against Cuban scholars. I think those are all things to be thought about. Now the BDS movement is a different matter. First of all, we have to make a distinction between the BDS tactics and the BDS movement. They happen to be quite different things. So, BDS tactics in the Israel Palestine case, were actually initiated in 1997 by an Israeli group, Gush Shalom, Uri Avnery’s group, a strongly anti-occupation, militantly anti-occupation group played a very significant role, still do. They proposed boycott of the settlements and divestment from anything involving the settlements. And I myself haveDeath of Molly Bish

Molly Anne Bish (August 2, 1983 – June 27, 2000) was a sixteen-year-old American girl from rural Worcester County, Massachusetts, who disappeared while working as a lifeguard in her hometown of Warren, Massachusetts. Her remains were found three years later in neighboring Hampden County after what became the largest search in the state's history.

Disappearance
In the summer of 2000, 16-year-old Molly Bish began working as a lifeguard at Comins Pond in Warren, Massachusetts.  On June 26, the day before Molly's disappearance, her mother, Magi, saw a mustached man in a white car parked in the lot of the beach where Molly's lifeguard post was located. Although he seemed suspicious at the time, she afforded him no further thought until after Molly's disappearance. On June 27,


Magi drove Molly to Comins Pond and dropped her off near the lifeguard station. Magi reportedly saw no sign of the stranger from the previous day or his white sedan. However, another witness reported that he saw a man matching the stranger's description in the pond's parking lot just minutes before Molly arrived. A local worker also reported that he saw a similar car parked at a cemetery connected to the pond by a path. Magi Bish was the last known person to see Molly before her disappearance. Several hours later, police contacted Molly's parents, informing them that no lifeguard had been on duty all day and that Molly's belongings had been left unattended at her station.

Body discovery
An extensive search was immediately launched. It was to become theQ:

Creating index on schema binding view in SQL Server

I am trying to create index for schema binding view. This view contains union all operator and some joins also. How can I create an index for this view? Because I am using the type of views in my procedure using left join. So I have to improve performance.
For example
create table a
(
     prodid int,
     prodname varchar(100)
)

insert into a values(1,'ramesh')

create table b
(
     prodid int,
     prodname varchar(100)
)

insert into b values(2,'kumar')

create view v1
with schemabinding
as
     select tb1.prodid, tb1.prodname
     from dbo.a tb1
     union all
     select tb2.prodid, tb2.prodname


isn’t their fault that people use them for so long. But I want to highlight the dangers that can arise,” his father, David, was quoted as saying.

In a statement, Microsoft, who manufacture the Xbox console, said, “We have always encouraged responsible game play through our education campaigns. We recommend that gamers take periodic breaks to exercise and do other things”Saudi coalition statement

"We take this report very seriously and it will be fully investigated as all reports of this nature are," a spokesman for the Saudi-led coalition told Reuters.

Al-Masirah, the Houthi-controlled TV station, said on its Twitter account that 33 people had been killed and 55 wounded.

Saudi Arabia and its allies have been accused of multiple war crimes by rights groups since entering the war in Yemen in 2015.

Its bombs have killed hundreds of civilians at hospitals, schools and markets.

The Saudi military conducts internal investigations and has regularly cleared itself of wrongdoing.

The Western-backed alliance has been fighting a war for three years against the armed Houthi movement which controls the area and much of northern Yemen.

It has launched thousands of air strikes in a campaign to restore the


               params.page
            }
        }
    }
</script>

A:

how to know when dynamic component has fully loaded ?

You can use @hook:mounted for every component dynamic or not to indicate that the component is loaded.
e.g.
<component :is="current_page" @hook:mounted="doSomething"></component>

Check codesandbox example

sales impact Lockheed's bottom line.

It'll be Navy over Army.

The Navy has not been as nearly as essential over the last dozen years of war as the other services, but that is changing. As China's first aircraft carrier weighs anchor just as that country flexes its muscle in the South China Sea, look to see the U.S. Navy become more of a funding priority. Even the troubled and expensive Littoral Combat Ship (LCS) by Lockheed Martin may stay afloat. The first LCS has been on its maiden voyage in the South Pacific, and the Navy hopes to buy 52 in all. Despite satellites and drones and long-range aircraft, most of the world's trade goes by water, and whoever rules the waves rules the world.

This is my riskiest prediction. NASA


Firefighting course deal signed for Oman

The International College of Engineering & Management (ICEM) has signed a memorandum of understanding with CAA International (CAAi), the state-to-state advisory arm of the UK Civil Aviation Authority (UK CAA) for new training in Oman

Signed by Affan Khalfan Al Akhzami, ICEM Managing Director and CEO, Maria Rueda, CAAi Managing Director and witnessed by Paul Gregorowitsch, CEO of Oman Air, the MoU supports the extension of ICEM's CAAi accredited airport rescue and fire fighting training, into new geographic locations.
Under the existing agreement, ICEM is an accredited CAAi training provider and authorised by the UK CAA to provide training in Oman on the structured learning programme for rescue fire fighting personnel in accordance with UK CAA CAP 699 - Standards for the Competence of Rescueand Fire Fighting Service (RFFS) Personnel.
Under the MoU, CAAi has also offered to provide training consultancy services in Oman, through a blend of theoretical and on-the-job training programmes.
Since gaining full CAAi accreditation in 2013, ICEM has trained hundreds of airport fire fighting professionals to UK CAA CAP 699 standards.
After the signing ceremony, Akhzami said, "I believe that the combination of ICEM's reputation for training and education coupled with CAAi's international brand will form a formidable partnership, not only in Oman but also across the region. We at ICEM are proud to work with internationally recognised bodies who can strengthen Oman's organisational capability and help to develop and nurture local Omani human capital. I look forward to a long, strong and prosperous relationship".

The Abu Dhabi Aviation Group (ADA), the


to work.”

“I’m sorry, too,” Berklee said quietly, standing over the sink. Her hair obscured her face.

As Doyle pulled on his coveralls, he fought the overpowering sense of helplessness. His wife, whom he dearly loved, had been spiraling downward since he’d known her, but he always thought his steady affection could somehow forestall it. Now, though, as anything does in a whirlpool, she was moving faster as she neared the center. If something didn’t change, and change soon, she would be lost to him down that great cosmic drain that swallowed wayward souls like hers.

In the distance, a coyote howled its final cry before sliding into its burrow for the day.

And something howled back.

High in the mountains that overlooked Needsville, Bliss Overbay stood on her deck and looked downfor now, he sat on the fender and began to play, sad minor chords that sounded like thin tendrils of the agony inside him.

After a few moments, his fingers froze in mid-chord. He definitely felt watched.

He saw no sign of people, and mentally ran through the list of large animals in his guidebook. Neither coyote nor deer would attack an adult, even a solitary one, it promised. But a bear, now that was a scary thought. Had his car stalled near a hidden den with a cub? Was he about to be slashed open and devoured by five hundred pounds of black-furred maternal fury? Careful to make no sudden moves, he placed his guitar back in its case and slowly closed the trunk.

Then he spotted his watcher.

A boy


on the dotted line in Nashville or L.A., you might not remember. I’ve seen it happen. There’s a song on the radio I know for a fact a fella who lives over on the highway toward Bristol wrote, but you don’t see his name on it. And ain’t no checks in his mailbox.”

The mechanic resumed work, and Rob tried to think of some way to convince him he meant no harm. But he wasn’t sure that was the truth. If the sequined man’s ludicrous story turned out to be right, what Rob sought here needed to be shared with the world. What would he do if he did find it, if it actually worked, and if he could, in fact, take it for his own?

Doyle dropped the ratchet              events = [events]

        except Exception as e: # pylint: disable=invalid-name
            print("Error parsing json file: {0}".format(e))
            return 0

        bad_key = TestExtensionTelemetryHandler.BAD_EVENT_KEY
        return len([e for e in events if bad_key not in e or not e[bad_key]])

    @staticmethod
    def _create_random_extension_events_dir_with_events(no_of_extensions, events_path, no_of_chars=10):
        if os.path.isdir(events_path):
            # If its a directory, get


re.search(regex_pattern, event.childNodes[0].nodeValue)
                if regex is None:
                    continue
                param_values.append(regex.group('value'))

        return param_values

    @contextlib.contextmanager
    def _create_extension_telemetry_processor(self):

        def http_post_handler(url, body, **__):
            if self.is_telemetry_request(url):
                extension_telemetry_processor.event_body.append(body)
                        extension_telemetry_processor.run()

                    telemetry_events = self._get_handlers_with_version_from_event_body(extension_telemetry_processor.event_body)
                    self._assert_handler_data_in_event_body(telemetry_events, ext_names_with_count, expected_count=max_events)

                pattern = r'Reached max count for the extension:\s*(?P<name>.+?);\s*.+'
                self._assert_event_reported(mock_event, ext_names_with_count, pattern)

    def test_it_should_send_the_latest_events(self):
        max_events = 5
        no_of_extension = 2


in expected_mapping:
                extension_event_key = expected_mapping[telemetry_key]
                telemetry_data = telemetry_event_map[telemetry_key]

                # EventName = "HandlerName-Version" from Extensions
                extension_data = ["{0}-{1}".format(handler_name, v) for v in extension_event_map[
                    extension_event_key]] if telemetry_key == GuestAgentGenericLogsSchema.EventName else \
                extension_event_map[extension_event_key]

    as described in Refs. [@caloz2005book; @Lai2004Caloz; @caloz2004novel]. Each capacitor $C_l$ will have a stray series inductance $L_r$ giving it a self-resonance frequency $\omega_C = 1/\sqrt{L_r C_l}$. Similarly, each inductor $L_l$ will have a stray shunt capacitance $C_r$ resulting in another self-resonance frequency $\omega_L = 1/\sqrt{L_l C_r}$. Figure \[fig:meta-schem\](b) shows a schematic of a composite LHTL including these stray reactances. As first described in Ref. [@caloz2005book], a Bloch-Floquet analysis can be applied to such a composite LHTL to obtain the dispersion relation between wavenumber $k$ and frequency $\omega$. We include our own derivation in Appendix \[appendix:Derivation of dispersion relation\] and obtain the following expression [@Lai2004Caloz; @caloz2004novel]: $$\begin{split}
k(\omega)=&\frac{1}{\Delta x}\times\\
&\cos^{-1}\left[1-\frac{1}{2}\left(\omega L_r-\frac{1}{\omega C_l}\right)\left(\omega C_r-\frac{1}{\omega L_l}\right) \right].
\end{split}\label{eq:Caloz-CRLH-disp}$$ Figure \[fig:meta-schem\](c) includes a plot of $\omega(k)$ obtained by inverting Eq. (\[eq:Caloz-CRLH-disp\]). Similar to the corresponding curve from Eq. (\[eq:ideal-LHL-disp\]), the band becomes flat


simultaneously \[Fig. \[fig:LSMS21\](b)\]. In Fig. \[fig:LSMS21\](d), the density plot of $\mathscr{R}(x, y_0, f)$, where $y_0$ indicates the location of the line scan, again shows the sharp features at the resonant frequencies, but also exhibits fine structure along the scan direction. Thus, it is clear that the LSM imaging of the device can be used to investigate resonances in the metamaterial and their corresponding standing-wave patterns.

![(LSM photoresponse compared with Sonnet current and charge density simulation: (a) Reflectivity map from LSM showing details of metamaterial layout in the imaged area. (b) 2D distribution of LSM photoresponse $\mathscr{R}(x,y, 3.44\,{\rm GHz})$ for the $n=40$ mode. Bright (dark) regions correspond to large (small) PR signal. Sonnet simulations of the $n=40$ mode (c) charge density and (d) current density. \[fig:ZoomedIn\]](LSM-ZoomedIn){width="3.35in"}

![image](LSM-array){width="7in"}

We then perform 2D scans of $\mathscr{R}(x,y,f)$ while exciting one ofthe metamaterial modes. In Fig. \[fig:ZoomedIn\](b), we present such a 2D scan for the $n=40$ mode at 3.34 GHz, which is the next-to-lowest resonant frequency in the device. The LSM image exhibits a clear standing-wave pattern with two antinodes along the length of the transmission line. We perform numerical electromagnetic simulations of our metamaterial layout using Sonnet, as aredescribed in detail in Sec. \[sec:Sonnet\]. Figures \[fig:ZoomedIn\](c, d) contain plots of the simulated charge density and current density in the metamaterial, also excited on the $n=40$ mode. With the application of LSM imaging to superconducting structures, the interaction of the laser spot with the superconductor can produce a bolometric response, with both inductive and resistive components, due to local heating of the superconductor by the locally absorbed laser power. In addition, there can


the experimentally measured spectrum, although there are notable deviations, particularly at the lowest frequency modes. Both the Sonnet and experimental spectra exhibit the highest density of modes around 6 GHz, in contrast to the prediction from Eq. (\[eq:Caloz-CRLH-disp\]) that the mode density should be highest just above $\omega_{IR}$ where the band for the ideal circuit is flat. We also observe good agreement between the resonance frequencies from the simulated spectrum, theoretical dispersion relation from Eq. (\[eq:Caloz-CRLH-disp\]), and the experimentally measured values from both the ADR and LSM over much of the frequency range of our measurements (Fig. \[fig:Freq-mode-all\]). However, there are discrepancies between these various methods for the modes near the low-frequency end of the spectrum.

![(a) $|S_{21}(f)|$ from Sonnet simulation (red) offset by 60 dB compared with measured LHTL spectrum from ADR atreasonably well with Eq. (\[eq:QcLHL1\]) for lower values of $n$, but begin to deviate significantly for higher $n$ modes starting around $n \sim 30$. From fits to extract $Q_c$ from the resonances in our Sonnet simulations, the $Q_c^{-1}$ values for the nonstaggered inductor configuration follow the dependence of Eq. (\[eq:QcLHL1\]) rather closely. However, the values from the Sonnet simulations of the same staggered-inductor layout as with our experimental device also follow the trend of excess coupling loss for the highest $n$ modes. This effect is likely a consequence of the short wavelengths for these high-$n$ modes, which are strongly influenced by the layout of the inductors, as well as the integrity of the ground plane across the chip (Appendix \[appendix:ImpGround\]).

Conclusions {#sec:conclusions}
===========

In conclusion, we demonstrate superconducting thin-film metamaterial resonators that produce dense


in the previous appendices to investigate the coupling loss for a discrete transmission line resonator. For a resonator formed from a continuous transmission line with characteristic impedance $Z_0$ equal to the load impedance, when $\omega_n C_c Z_0 \ll 1$, the coupling loss is given by [@schuster2007circuit] $$\frac{1}{Q_c}=\frac{4Z_0^2C_c^2{\omega_n}^2}{n\pi}=\frac{4nZ_0^2C_c^2{\omega_0}^2}{\pi}\label{eq:QcTrans},$$ where we make use of the fact that such a transmission line will have a linear dispersion, resulting in harmonic resonances $\omega_n = n \omega_0$. In contrast, we use AWR Microwave Office to simulate a discrete transmission line resonator and extracted $Q_c$ for all of the resonance modes. As plotted in Fig. \[fig:Qc-1VSn\], there are dramatic differences in the variation of $1/Q_c$ with $n$ for all but the lowest $n$ modes.

![Solid line is $1/Q_c$ expression of a continuous transmission line resonator, as describedeach mode of a discrete transmission line resonator then mapping this onto the expression for $Q_c$ for the simple LC circuit. We do this below – first for an RHTL resonator, then for a resonator based on an LHTL.

For a basic LC circuit with symmetric input and output coupling capacitors $C_c$ to load and source resistors $R_0$ and resonance frequency $\omega_0^{LC}$, when $\omega_0^{LC} C_c R_0 \ll 1$, then $Q_c$ is given by [@Goppl08; @Oconnell08]

$$Q_c=\frac{\tilde{C}}{2\omega_0^{LC} C_c^2R_0}\label{eq:ExternalQ},$$

where $\tilde{C}$ is the capacitance of the LC circuit. For a discrete RHTL or LHTL resonator, if we replace $\omega_0^{LC}$ with $\omega_n$ for mode $n$ and determine $\tilde{C}$ corresponding to mode $n$, we can then use this expression to compute $Q_c$.

For an ideal RHTL, we first compute the total electric field energy stored in the


and charge density distributions and these are consistent with Sonnet simulations (Fig. \[fig:ZoomedIn\]). In contrast to standing waves on a continuous transmission line resonator, where the antinodes in the current will always match the nodes in the voltage and vice versa, for our images of the $n=40$ mode for our metamaterial resonator, we observe the current density and charge density distributions to be spatially in phase. In this Appendix, we show that this behavior is expected for a discrete transmission line resonator when exciting a high-$n$ mode; while for a low-$n$ mode, the two distributions are spatially out of phase, as with a conventional continuous resonator. We begin by revisiting the treatment in Appendix \[sec:Impedance of general terminated discrete transmission line\], where Eqs. (\[eq:VmwithGamma\]) and (\[eq:ImwithGamma\]) give the voltage and currentare spatially out of phase, as one would expect for a continuous transmission line resonator. However, if we examine the large-$n$ limit, for mode $n=N-1$, we obtain $$\begin{aligned}
\left|v_{m}^{C_l}(N-1)\right|&\approx 4 V_0^+\left|\sin\left[\left(\frac{N-1}{N}\right)\left(m-1\right)\pi\right]\right|\label{eq:E5}\\
\left|i_{m}^{L_l}(N-1)\right|&\approx 4 I_0^+\left|\sin\left[\left(\frac{N-1}{N}\right)\left(m-1\right)\pi\right]\right|\label{eq:E6},\end{aligned}$$ thus, the voltage and current standing wave patterns are now in phase spatially. This behavior is also reflected in our Sonnet simulations. In Fig. \[fig:volcurPattern\], we compare the standing wave patterns for mode $n=3$ and 39, computed from the magnitude of Eqs. (\[eq:V\_Clm\])-(\[eq:I\_Llm\]) with the corresponding Sonnet simulations of the charge density and current density. In addition to the Sonnet simulations and Eqs. (\[eq:E5\])-(\[eq:E6\]), we can also observe this behavior in the relative positions of the standing-wave antinodes in the LSM images, as mentioned earlier for Fig. \[fig:ZoomedIn\]. In Fig \[fig:LSMPhasePattern\], we present high-resolution LSM images using a smaller laser spot


so that the unit cell size increased by $6\,\mu{\rm m}$. Thus, the total length of the non-staggered metamaterial resonator must increase by 252 $\mu$m beyond that of our measured device.

![Sonnet simulations of $S_{21}(f)$ for non-staggered (orange, with -40 dB offset for clarity) and staggered (blue) inductor layouts. Note that the blue curve is the same as in Fig. \[fig:sonnet\]. \[fig:staggerspectrum\]](42cellOneSideSpectrum){width="3.35in"}

In Fig. \[fig:staggerspectrum\] we compare the simulated $S_{21}(f)$ spectra for the original staggered and non-staggered inductor configurations. Although both spectra follow the overall pattern expected for an LHRH resonator, as presented earlier, there are clear differences between the spectra for the two inductor layouts. In the case of the non-staggered inductor configuration, the infrared cut-off frequency is about 2 GHz higher than that for the staggered inductor layout used in our experiments.JAR file?
Thanks,

A:

Where can I find a copy of android.net as either source or JAR file?

There is no JAR file, strictly speaking, except as part of a firmware build.
The Android source code is available online, including the Java classes that are part of the android.net package.
However, getting this code to work on standard Java may be painful. I would recommend finding existing ordinary Java code.


   public static class ParamsTest
    {
        [SqlProcedure]
        public static void Test(out int p)
        {
            p = 5;
        }
    }
}

SQL:
CREATE PROCEDURE dbo.Test(@p int OUTPUT)
    AS EXTERNAL NAME [CLRTest].[CLRTest.ParamsTest].[Test];
GO

DECLARE @x int;

EXEC dbo.Test @p = @x OUTPUT;

SELECT @x;

Returns 5 as expected.

Now, if you're trying to return an array in an output parameter, I don't think that's supported, save for the exceptions noted here. If that's what you're looking to do, use a table-valued function or stored procedure to return a resultit has the appearance of a coordinated effort, with Britain
delivering the ultimatum.

MR. FLEISCHER: I'm not the spokesman for the Prime Minister. The United States
welcomes the comments.

Q Did he see the speech, the President?

Q What kind of coordination was there between the United States and Great
Britain about the Prime Minister's remarks? Because there were reports yesterday
that he was going to go so far as saying time has run out on the Taliban, and
that they now will face military strikes.

MR. FLEISCHER: I think the Prime Minister's remarks speak for themselves, and
the Prime Minister speaks for himself and for his nation. His remarks are
welcome.

Q -- agree with those remarks?

Q Was there consultation --

MR. FLEISCHER: What's that?

Q Was there any coordination between the U.S.? Did the U.S. have an advanced
indication of exactly


how we get information.

MR. FLEISCHER: -- in which that information is brought in, includes sources and
methods of how the United States gets that information. So it's a quandary of
how to share that information with the public, with the press, yet not let it be
available to terrorists who would benefit from that knowledge.

Q So the administration believes that it's enough to convince governments --

MR. FLEISCHER: -- but again, the United States is very satisfied that the
conversations it's been having around the world with our allies and with friends
in the Middle East and others, is leading to sufficient action that these
nations are joining with us. And I think that speaks volumes for itself.

Q Can I just go back to the Taliban Ambassador to Pakistan's comments today,
saying that they'd be opendo
everything possible, working through relief organizations and others, to get
food to the people of Afghanistan in the future.

Q The other question was about Rumsfeld. Apparently the Pentagon has announced
that he is headed to the Middle East. Can you tell us why, and what the
President has asked him to do?

MR. FLEISCHER: DOD is briefing as we speak, so you're free to leave here and
listen to the DOD briefing. He's going to several nations in the Middle East,
and they'll be able to give you the precise nations.

Q Why him, not Powell?

Q Has the President asked him to do something in particular, or is this solely
related to his own duties within the Defense Department?

MR. FLEISCHER: No, he's going over there for information-sharing and for
consultation with friends.

Q To share information along the


comments
coming from some quarters that the reason that we're doing this now is because
we need to do something to reach out to Arab countries for this coalition? And
could you also address the question of whether the President still feels, as he
has said in the past, that Yasser Arafat needs to do more to control violence?

MR. FLEISCHER: On the second point, the President does feel that, yes. And
that's why the President is calling all parties to make 100 percent effort, so
that we can begin the process that leads to the implementation of the Mitchell
Accords, which can have a conclusion at the end of a negotiated dialogue, which
is something, frankly, that Prime Minister Sharon said as recently as September
24th, that -- let me put it in Prime Minister Sharon's wordsworkers, on the budget with the appropriation bills that are now
overdue, that are pending action, probably this month.

So it was a collection of ideas from the leadership, an attempt to arrive at
principles then that those leaders can take back to the Hill so that the various
members of the Hill can weigh in now and move it along.

Q -- going to meet again this week?

MR. FLEISCHER: This is four follow-ups.

Q Who's counting? (Laughter.) Are they going to meet again this week?

MR. FLEISCHER: There's nothing on the schedule at this time.

Q Ari, it's been a little more than a week since the President turned out his
request for freezing of assets around the world. When the Treasury provided us
with a list yesterday of the countries that have acted on that request,


ideas on how to filter an Observable that returns an array and the passed in function in the filter returns an Observable of true or false based on a value on an object in the array?
Thanks

A:

Looks like you're using RxJS 5.0 in your snippets, but here's a possible solution with RxJS 6.0.
You should be able to retrofit this.
Aspects to point out:

switchMap() accepts the most recent collection of users returned
Having to invoke isUserAdministratorForModule for each user means you end up with Observable<boolean>[]
Using of(user) with forkJoin() associates each user with their isUserAdministratorForModule result
The merge() then collects each user-result value observable back into a single stream
Finally, the combination of filter() and map() weeds out the users of interest

const { forkJoin, merge, of } = rxjs;
const { filter, map, switchMap= p(z_{1}, -\det)$.

\[cor-uptoscalars\] Let $n, X, V$ and $p$ be as in Proposition \[prop-generalization\], and suppose $p(s, t) = (-t^{k})u(s, t)$ and instead that the basis of $V$ is permuted up to scalars, that is $g(v_{x}) = (\det(g))^{k}v_{g(x)}$. Then $(X, u(s,t), I_{2}(n))$ exhibits dihedral sieving.

Proposition \[prop-generalization\] shows that $V = p(z_{1}, -\det)$ in $\operatorname{Rep}(I_{2}(n))$. Proposition \[prop-uptoscalars\] then implies that $(X, u, I_{2}(n))$ exhibits dihedral sieving since $\det^{k} = (-t)^{k}|_{t=-\det}$.

Instead of writing a symmetric polynomial in $a$ and $b$ as a polynomial in $a + b$ and $ab$, we can equivalently make the substitution $a = \frac{s + \sqrt{s^{2} + 4t}}{2}$ and $b = \frac{s - \sqrt{s^{2} + 4t}}{2}$, as in Proposition \[prop:fibonomial-thm\], which satisfies $a + b = s$ and $-ab = t$. In particular, we have $\{n\}_{s=a+b,t=-ab}


be the set of dissections of a regular $(n+2)$-gon using $k$ noncrossing diagonals, the triple $$\left(X,(-r)^{f(n,k)}p_n(s,-r),I_2(n)\right)$$ exhibits dihedral sieving, where $p_n(s,r)=\tilde{S}_{n,n-1-k}(q,t)$ is the little $q,t$-Schröder number written using the basis $s=q+t,-r=qt$ and $f(n,k)$ is a function of $n$ and $k$.

Further Questions
=================

The case of even n
------------------

Each of our proofs of instances of $I_2(n)$-sieving specifically relied on $n$ being odd. In the case of $n$ even, empirical evidence seems to suggest any possible instances of dihedral sieving for $k$-subsets, $k$-multisubsets, or noncrossing partitions will not be given by taking an obvious $(s,t)$-analogue polynomial when specializing to generators of the representation ring of $I_2(n)$. This is especially true since the representation ring is different for $n$ odd and even. Nonetheless, the character values for each of these group actions can beanalogues related to Lucas sequences. [*Integers*]{} [**10**]{} (2010). 697–703.

J. Haglund, The $q,t$-Catalan numbers and the space of diagonal harmonics. University Lecture Series **41**, American Mathematical Society, Providence, RI, 2008.


your blog/website out there in front of millions of people,,, increasing your visibility ten notches & getting you more branding.
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Backlinks are fromthe undead, blood and gore. One crucial gameplay element in many of these games is the low quantity of ammunition, or number of breakable melee weapons. Notable examples include Silent Hill and Resident Evil.

Nostromo was the first survival horror game, developed by Akira Takiguchi, a Tokyo University student and Taito contractor, for the PET 2001. It was ported to the PC-6001 by Masakuni Mitsuhashi (also known as Hiromi Ohba, later joined Game Arts), and published by ASCII in 1981, exclusively for Japan.

Metroidvania
Metroidvania games are a subgenre of Platformer (named after its two first well-known franchises, Metroid and Castlevania) that feature large interconnected world maps the player can explore, but access to parts of the world is limited by doors or other obstacles that can only be opened


UK Prime Minister Boris Johnson fended off a party revolt on Tuesday over Britain's decision to allow China's Huawei to build parts of its 5G infrastructure.

A group of Conservative party rebels tried to pass a bill which would rip Huawei out of Britain's telecoms by the end of 2022. The government won the vote by a narrow margin of 24 votes.

Digital minister Oliver Dowden said that ideally Britain would exclude all "high-risk vendors" such as Huawei, but that was impossible given its dominant market position.

Visit Business Insider's homepage for more stories.

British Prime Minister Boris Johnson defeated his first party rebellion on Tuesday over a government decision to allow China's Huawei to have a role in building Britain's 5G phone network.

The UK decided in January it would allow Huaweitransparent line image. This causes deterioration of the super-imposed letter image quality.
In order to solve the above-described problem, systems using a hydrazine derivative have been proposed as disclosed in JP-A-62-80640, JP-A-62-235938, JP-A-235939, JP-A-63-104046, JP-A-103235, JP-A-63-296031, JP-A-63-314541, and JP-A-64-13545, but sufficient effects have not yet been obtained, leaving a need for further improvements.


the 3- and 8-year follow-ups. At 3 years, the additional treatment group perceived their drinking problem as being more serious than did the untreated group and was more likely to have drinking-related problems; by 8 years, individuals who had obtained additional treatment were more likely to be abstinent, but still perceived their drinking problems as being more serious. Compared to individuals who completed treatment in Years 1-3, additional treatment group members had more severe drinking and functioning problems at 3 and 8 years. More involvement with formal outpatient treatment or AA was associated with more improvement on drinking indices. Persons with alcohol use disorders who elect to enter formal treatment or AA relatively soon after acknowledging their drinking problems experience better drinking-related outcomes than do those who receivetook issue with the Trump administration’s handling of its ongoing trade war with China, saying that while “tak[ing] on China” was necessary, “to take on China there has to be a multilateral approach … one country can’t take on China.”

Wallace also questioned Trumka on the level of rank-and-file support for Trump, who has frequently claimed only union leadership oppose his policies.

“He came to our members and said ‘I’m going to change the rules of the economy and they believed him,’ ” Trumka said, adding that in the meantime, Trump has “opposed every increase in the minimum wage” and proposed cuts to Social Security and Medicare.

“I’ve tried to call balls and strikes with him and I have to say unfortunately while he may not even know what his administration


is doing, they’ve done more to hurt workers than they’ve done to help them,” Trumka said.

“Our members are still waiting for the supposed greatness of this economy to reach their kitchen tables,” he added.//
//  ViewController.swift
//  SwiftSpace
//
//  Created by Simon Gladman on 20/08/2015.
//  Copyright © 2015 Simon Gladman. All rights reserved.
//

import UIKit
import SceneKit
import CoreMotion

class ViewController: UIViewController
{

    let buttonBar = UIToolbar()

    let cameraDistance: Float = 2

    let sceneKitView = SCNView()
    let cameraNode = SCNNode()

    var initialAttitude: (roll: Double, pitch:Double)?
    let motionManager = CMMotionManager()

    let currentDrawingLayerSize = 512

    var currentDrawingNode: SCNNode?
    var currentDrawingLayer: CAShapeLayer?

    let hermitePath = UIBezierPath()


            self.cameraNode.eulerAngles.y = Float(self.initialAttitude!.roll - deviceMotionData.attitude.roll)
                self.cameraNode.eulerAngles.x = Float(self.initialAttitude!.pitch - deviceMotionData.attitude.pitch)
            }
        }

    }

    override func touchesBegan(touches: Set<UITouch>, withEvent event: UIEvent?)
    {
        super.touchesBegan(touches, withEvent: event)

        currentDrawingNode = SCNNode(geometry: SCNBox(width: 1, height: 1, length: 0, chamferRadius: 0))
     the BIA are biased against the State and favor the Tribe because Mr. Hawkins is a tribal member and former elected Tribal Chairman [-] hold[] no validity whatsoever." (A.R. 3772, 4987, 2576, 1105, with bracketed material added to aid proper reading). It makes no sense to read the sentence as urged by Plaintiffs to suggest that Hawkins called the State biased. Read as Plaintiffs urge, the sentence would be the following nonsense: "The State's comments ... are biased against the State and favor the Tribe," and, the final clause of "holds no validity whatsoever" likewise would be rendered surplusage.
Plaintiffs also argue that Superintendent Hawkins' exhibited bias by failing to address the same Due Process Clause argument Plaintiffs now raise in this Court. However, in response to Plaintiffs' assertion


813, 106 S.Ct. 1580, 89 L.Ed.2d 823 (1986) (violation of due process for an Alabama Supreme Court justice to participate in an action seeking punitive damages from an insurance company when the justice was a plaintiff in a very similar case pending below)); Gibson v. Berryhill, 411 U.S. 564, 93 S.Ct. 1689, 36 L.Ed.2d 488 (1973) (an administrative board composed of private optometrists had a pecuniary interest of such "sufficient substance" that due process precluded it from presiding over a hearing against competing corporate optometrists); Ward v. Vill. of Monroeville, Ohio, 409 U.S. 57, 93 S.Ct. 80, 34 L.Ed.2d 267 (1972) (mayor's position of traffic court judge violated due process where mayor was responsible for producing revenue for the city, and the fines imposed by his court amountedwill ... be confined to rare instances."); see also Bracy v. Gramley, 520 U.S. 899, 904, 117 S.Ct. 1793, 138 L.Ed.2d 97 (1997) ("[M]ost questions concerning a judge's qualifications to hear a case are not constitutional ones, because the Due Process Clause ... establishes a constitutional floor, not a uniform standard.") (citations omitted). Here, Superintendent Hawkins was not involved in the Tribal Council's decision to submit trust applications for the four parcels at issue to the Secretary. In fact, Hawkins' service as Tribal Chairman ended nearly six years before he became Superintendent. (Doc. 12, 15). Superintendent Hawkins received his salary regardless of whether he took the four parcels of land into trust. Any general benefit that Superintendent Hawkins might receive as a tribal member from the Department of


on the German parcel, $1,300.86 on the Gardner parcel, and $1,474,80 on the Smith parcel. (A.R. 2073, 4496, 3259, 610). The RD then compared these figures to the $2,789,388 that the County collects in property taxes each year and found that, in each case, the County's loss would be insignificant. Id. In her review of the Peters, German, and Gardner Parcel, the RD also considered the impact that accepting the land into trust would have on the Wilmont and Sisseton School Districts. (A.R. 2073, 4496, 3258). The RD further noted that she had received no documents showing that "the loss of taxes will impose economic distress on the State and other local governments." (A.R. 2073, 4495, 3259, 610). Plaintiffs contend that this analysis was insufficient, however, because theof oppression and paternalism." Mescalero Apache Tribe v. Jones, 411 U.S. 145, 152, 93 S.Ct. 1267, 1272, 36 L.Ed.2d 114 (1973) (quoting H.R.Rep. No. 1804, 73d Cong., 2d Sess., 6 (1934)). In order to stem the staggering flow of land from Indian to non-Indian hands, the IRA set forth that "no land of any Indian reservation . . . shall be allotted in severality to any Indian." 25 U.S.C. § 461. Congress also tried to replenish Indian lands by permitting the Secretary of the Interior to acquire land in trust for Indians, noting that land held in trust is exempt from local and state taxation. 25 U.S.C. § 465.
South Dakota I, 314 F.Supp.2d at 950-51. Plaintiffs now argue that accepting the land into trust has "not been shown


Difference in Physician- and Patient-Dependent Factors Contributing to Adenoma Detection Rate and Serrated Polyp Detection Rate.
Adenoma detection rate (ADR) is correlated with the risk of interval colorectal cancer and is considered as a quality benchmark for colonoscopy. Serrated polyp detection rate (SPDR) might be a more stringent indicator of quality in polyp detection. To evaluate in a 2-year monocentric observational study patient-dependent and endoscopist-dependent factors influencing ADR and SPDR in daily practice. We determined ADR and SPDR. We collected patient-dependent factors and endoscopist-dependent factors. Links between these data and detection rates were assessed by uni- and multivariate analysis. A total of 11682 colonoscopies were performed (female: 54.3%; male: 45.7%; median age 58) by 30 endoscopists (female: 9; male: 21). ADR and SPDR were 29.2% and 8%, respectively. Inhandling of twenty-two known small exceptions to Conjecture H when $n \equiv 1 \text{ or } 2 \pmod{4}$:
$$ 5,10,13,34,37,58,61,85,130,214,226,370,526,706,730,829,1414,1549,1906,2986,7549,9634 $$
which they say are "probably all the exceptions."  While most of these are already sums of two squares, I found three which are not so: $214,526,1414$.


Q:

How can I determine the turning profile of an articulated vehicle?

I'm working on a project that requires me to design an overload control centre where overloaded trucks are allowed to redistribute or shed some of it's cargo in order to continue to travel on the highway.
As we are pressed for space I would like to make the design as economical as possible and maybe force the vehicles in a certain flow direction in order to ensure the longevity of the driving surface. But before I can do this I need to understand what kind of maneuvers are possible for the vehicles.
I am aware of sources that that has done that, e.g. AASHTO. There are also various plugins that exist for different CAD applications, some of which are freeafter the fact accurate 3D CAD models of car and motorcycle layouts for custom parts. They would be invaluable for modeling a truck 3D steering geometry.  Generally I use Solidworks for the CAD modeling.
Tell the manager what you want to do, ask permission.  It really HELPS to bring along a dozen donuts and coffee before you arrive.
You can easily measure most geometry on a stationary truck (engine off) and recalculate everything you will need to know.  The only thing that might be tough is to figure out maximum steering motion.  On many trucks you can figure that out from grease tracks & wear marks, but not always.  Often the steering on large trucks has physical stops that mark the ends of steering


and a tie in Ohio.

The Quinnipiac polls have generally shown Clinton doing somewhat worse than other surveys, so what’s most significant is the downward trend for her, which matches that found by Marist and Marquette.

David.Lauter@latimes.com

For more on Politics and Policy, follow me @DavidLauter

ALSO

Clinton campaigns with a veepstakes favorite in Virginia

Hillary Clinton calls on Americans to reject ‘divisive’ Trump candidacy

Justice Ruth Bader Ginsburg apologizes for ‘ill-advised’ criticism of Donald Trumptotal number of seats available within the region grew to 7.02 million from 6.31 million.

“Much of the growth in the Middle East is spurred by increased flights in the region to a number of Asian and European destinations. Dubai International Airport is home to a growing airline, which is supported by a government interested in opening international markets, catapulting the airport into the position of being a leading international airport,” said Peter von Moltke, Chief Executive Officer, UBM Aviation. For the first time Dubai’s capacity has surpassed the capacity constrained New York’s JFK.

Within Central and South America*, seat capacity increased 10%, to a total of 21.4 million, and flights increased 11% to a total of 207,277. Capacity (8%) and frequency (6%) increased to and from the region as


yet ears and nose like her father. Cotton Tail is her name, and she somewhat takes after her father. She's a bit pushy and bratty and always wants her way. She's assertive and never backs down. She sometimes takes advantage of her mother's kindness and naivety to her own daughter's misbehaving, and generally causes trouble at school between her classmates. She can be kind however, and does truly care about her friends and family. He special talent is making stuffed animals. She gets along great with Zephyr, and Zephyr treats her like his own.Angel and Zephyr butt heads a lot, considering they share one mare and both are quite pushy and impatient. They do love Fluttershy alot, so they try to keep their heads.Rose and Cotton are goodShare this story

Vatican City, 1 June 2013 (VIS) – At 8:00 yesterday evening, Pope Francis participated in the praying of the Rosary held in St. Peter’s Square concluding the Marian month of May. The celebration was presided by Cardinal Angelo Comastri, vicar general of His Holiness for Vatican City and archpriest of the Vatican Basilica. At the conclusion of the prayer and before imparting the Apostolic Blessing to the many faithful present, the Holy Father recalled the feast of the Visitation of the Blessed Virgin Mary to Elizabeth and offered a meditation dedicated to the mystery that shows how Mary faces life’s journey with great sensibility, humanity, and care.

“Three words sum up Mary’s attitude: listening, decision, and action. They are words that also show us the path before


cell, the shock is substantial. The damage which occurs to the load cell due to the shock of loading can be extensive. In addition the rigid fastening of the load cell to the steel in the stand below the load cell results in a second shock when the shock rebounds from the rigid stand.update. We’ll email Microsoft about this for comment. Oh, by the way, before we forget: we’re on […]

Microsoft has announced that its Facebook, Twitter, and Last.Fm update for Xbox Live will launch November 17 in the UK. This was spotted on the UK Xbox website. The public Beta is still slated for gold members during the middle of October. No word on if the US is getting the services the same day […]

Joystiq has posted a video demoing Twitter, Facebook, and Last.Fm for Xbox Live. The vid was taken during the Microsoft Open House event yesterday, where the fall Xbox Dashboard Update was previewed. Go on and watch past the break.

Twitter Latest

As if you need any reminding, Microsoft has released a press release which details the big dashboard


few hours when you sign in to Xbox LIVE you’ll receive a prompt to accept this mandatory update,” said the exec. “If you are signed into LIVE already, you […]

As reported by TheBBPS, Uncharted 2 features a host of Twitter integration options, allowing the game to automatically tweet when you earn Trophies, reach level milestones, and so on. There’s a bunch of pictures of it all working over there. Pretty cool. The game’s out on October 15 in North America, with a UK date […]

Bizarre Creations has announced Twitter support for its racer Blur. The news was confirmed during PAX today by Joystiq. No word on whether Twitter in the game will be integrated with Twitter on 360 this fall, but we sent a mail to see ifwe can find out more. Hit the link for the rest.

Microsoft’s cleared up yesterday’s tooing-and-froing on whether or not Facebook and Twitter will only be available to Gold Live members. In short, Silver member will get the soc media networks, but only for a “trial period”. The platform holder told VG247 in a statement this morning: Facebook and Twitter on Xbox LIVE will be free […]

Microsoft has stated that its earlier announcement regarding Facebook and Twitter on Xbox Live being for Gold Members only was “incorrect”. According to a MS spokesperson speaking with MCV, the company is still “formulating its plans” for the services. Granted, it stated: “Xbox Live Gold Membership will be required for Twitter and Facebook when they […]

In probably the most obvious announcement of the


news is not so good. Here’s the tweet: “Got a back-catalog announcement on Monday. It’s not X-Wing! I’m heading THAT rumor off at the pass!” Guess we’ll just have […]

Microsoft told EG today that 360 will have Twitter and Facebook functionality before the end of the year. “It will be before Christmas,” said marketing chap James Halton. “A lot of the background work’s been done for a lot of applications that are coming.” So there you go. Follow us on other electronic devices in […]

Naughty Dog co-president Evan Wells has tweeted that Uncharted 2 is going under a “difficulty tuning” as the game prepares for an autumn release. “We’re doing a playtest of the entire game of Uncharted 2 this weekend to begin our difficulty tuning,” said Wells.been shown to be effective, but are not without side effects. For example, the facial flushing induced by niacin is a major limitation in its use; fibrates cause liver dysfunction and skin rash; and statins are increasingly associated with myopathy. Thus, therapeutic options that are effective, easy to maintain, and have minimal side-effects are desirable to properly address this epidemic of cardiovascular metabolic abnormality. Moreover, current treatment modalities focus on each of these risk factors independently. In order to minimize adverse interactions between treatment modalities and simplify treatment regimens to encourage patient compliance, it is desirable for one treatment to address multiple facets of cardiovascular health.
More specific aspects of current treatments also have room for improvement. Triglyceride metabolism is believed to involve multiple tissues within the body and


clearance of TG's by simulating LPL. Both ApoCII and ApoCIII concentrations and synthetic rates have been closely tied to plasma TG concentrations in healthy patients and those with hyperlipidemia.
Several of these sites of regulation have been targeted by different drugs. Several drugs are currently used to block the initial absorption of TG and cholesterol via the gut, such as eztembamide. Nicotinic acid, or niacin, is believed to work via binding to HM74 receptors in adipose tissue, and via cAMP causes a reduced association of hormone sensitive lipase (HSL) with lipid droplets in adipose tissue, thus causing a decrease in FFA release from adipose tissue. Other drugs, such as the PPAR agonist fibrates, are thought to increase the oxidation of fats within mitochondria and peroxisomes, and thus decrease thegoal of a nutritional supplement is to achieve comparable or better results without negative side effects.
Fibrate treatments including fenofibrate (a prescription drug) commonly induce the undesirable side effect of liver toxicity. It is therefore desirable to achieve similar or improved efficacy of fibrates without such side effects. The effects of a composition of essential amino acids (EAAs) (i.e., those that cannot be synthesized by the body) and arginine was compared to the effect of fenofibrate in a similar population of elderly. In contrast to the EAA+arginine, fenofibrate treatment for 60 days had no significant effect on liver triglyceride. Plasma triglyceride concentration fell approximately 33%, as compared to the 20% reduction in those receiving EAAs+arginine. These results are shown in FIG. 2. Due to these positive effects in the


TG decreased after either a high fat or a high protein diet, as compared to a high carbohydrate diet. This substitution of substrate source is not restricted to dietary substitution: peritoneal dialysis patients receiving a 1.1% solution of amino acids instead of all glucose were shown to experience a 13% decrease in plasma TGs within 1 month of the solution change. Other studies have found similar results over 3 years of treatment.
Because carbohydrate intake is thus believed to induce increases in blood lipids in individuals with preexistent elevations, it is desirable for a composition for improving cardiovascular health to have minimal carbohydrates. This is especially desirable for elderly individuals who are often insulin resistant and cannot obtain nutrition from carbohydrates. Medium chain triglycerides are believed to be particularlyplay a role in the appearance of increased TG following a high carbohydrate diet. Diets high in carbohydrate are believed to increase the proportion of bile cholesterol, and disrupt the balance between bile acids and cholesterol.
Increasing the proportion of plant sterols in the diet also has been associated with decreased cardiovascular disease. Plant sterols, or phytosterols, are found in cellular membranes of numerous plants, and include steroids with a hydroxyl group in the three-position of the A-ring. Sterols are long chain fatty acid esters and are believed to bind cholesterol in the gut effectively in the gut and prevent its absorption. The three sterols believed to be the most effective in lowering plasma cholesterol are B-sitosterol, campesterol, and stigmasterol. A meta-analysis of multiple studies with plant sterols found


syndrome and Gorlin syndrome^\[^[@B20]^\]^. Neurofibromatosis type 1 is also prevalent in RMS cohorts, especially embryonal RMS (ERMS) and GURMS^\[^[@B21]^\]^.

Histology/pathology
-------------------

RMS is one of the small round blue cell tumours of childhood. It is a fast-growing, high-grade, primitive malignant mesenchymal tumour containing certain elements that are found in skeletal muscle. The following are essential for diagnosis: myofibrils, cross striations and positive immunohistochemistry staining for markers of muscle differentiation, e.g. desmin and myoD1.

There are 3 main histological variants: embryonal (80%), alveolar (15--20%) and pleomorphic (not typically found in the genitourinary tract of children). Botryoid and spindle cell are variants of ERMS. Botryoid RMS is associated with a younger age group and a genitourinary site. It has a predilection for hollow organs such as the bladder and vagina. Spindle cell RMS isabdominal pain or an abdominal or pelvic mass^\[^[@B58]^\]^. Children with peritoneal deposits (usually immature teratoma) may present with abdominal distension and ascites. Up to one-third present with an acute surgical abdomen^\[^[@B59]^\]^, often related to torsion or rupture. Other presentations include fever and constipation. More unusual presentations may be due to secondary hormonal effects or paraneoplastic syndromes, e.g. hypercalcaemia in ovarian dysgerminoma^\[^[@B60]^\]^.

GCT of the ovary
----------------

GCTs originate from the primordial germ cells of the urogenital ridge and can arise either in the gonads or along normal or aberrant migrational pathways. GCTs comprise two-thirds of paediatric ovarian tumours^\[^[@B57]^\]^. Approximately 25% of these are malignant^\[^[@B56]^\]^. The peak incidence is around 12 years^\[^[@B61]^\]^ and they are rare under 5 years of age. In decreasing order of frequency, the ovarian GCTs seen in childhood


evaluation of any testicular lesion. US can define the cystic or solid nature of a mass and its relationship to the testis. The distinction between intra- and extra-testicular masses is important because most intra-testicular lesions are malignant, whereas most extra-testicular lesions are benign (with the exception of paratesticular rhabdomyosarcoma). At US, CT and MRI, testicular tumours usually appear as discrete solid masses. They may contain calcification or hypoechoic areas due to the presence of haemorrhage or necrosis. Imaging of the chest, abdomen and pelvis are routinely performed to search for metastases. The abdomen and pelvis can be further evaluated by CT or MR. CT is, of course, necessary to evaluate for lung metastases.

Staging
-------

The COG have developed a staging system that accounts for the tumour marker status and surgicalof CPI International Holding Corp. and CPI International, Inc. CPI develops, manufactures and globally distributes components and subsystems used in the generation, amplification, transmission and reception of microwave signals for a wide variety of systems including radar, electronic warfare and communications (satellite and point-to-point) systems for military and commercial applications, specialty products for medical diagnostic imaging and the treatment of cancer, as well as microwave and RF energy generating products for various industrial and scientific pursuits.

Predator and Reaper are registered trademarks of General Atomics Aeronautical Systems, Inc.

Certain statements included above constitute "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements provide our current expectations, beliefs or forecasts


DNA replication and subsequent cell division in human embryogenesis and homeostasis, as well as in cancer development. In particular, CDK4/6 functions as a critical activator of G1 phase progression. The aim of therapeutic CDK4/6 targeting in cancer cells is to stop cell proliferation and restore cell cycle arrest in G1 phase, while minimizing or avoiding adverse side effects for cancer patients.

In this context, we designed and synthesized a series of novel hybrid compounds, including two essential pharmacophoric elements for HDAC and CDK, to identify combination solutions and augment response of HDACis in solid tumours [@B32]. As indicated by the suppression of HDAC and CDK, the hybrid molecule Roxyl-zhc-84 exhibits remarkable antitumour activity both *in vitro* and *in vivo* (**Figure [S1](#SM0){ref-type="supplementary-material"}**). Insight into the mechanism of this novel hybridwas performed using GraphPad Prism 5 software (GraphPad Software, Inc., La Jolla, CA). Unpaired Student\'s *t-*test was used for comparisons between two different groups. p\<0.05 was considered as significant. \* represents p\<0.05; \*\* represents p\<0.005; \*\*\* represents p\<0.001.

Results
=======

Roxyl-zhc-84 is the most potent antitumour compound among the derivatives
-------------------------------------------------------------------------

Based on the synergistic experimental results with mean CI \< 1 across relevant concentrations of both vorinostat and abemaciclib *in vitro* and *in vivo* (**Figure [S1](#SM0){ref-type="supplementary-material"}**), in our hybrid strategy, we merged two different pharmacophores to link two inhibitors together with neither a long chain nor high molecular weight. Vorinostat has been reported to bind strongly to the zinc cation or monodentate group, which plays a critical role in chelation to zinc ions for HDAC inhibitors. Analysing the X-ray co-crystal structure of


and a clearance of 1.027 L/h/kg. Its half-life (t~1/2~ = 8.361 h) and clearance rate (CL = 1.027 L/h/kg) in pharmacokinetic studies indicated that Roxyl-zhc-84 displays good stability *in vivo*. Together, these results indicate that Roxyl-zhc-84 presents favourable pharmacokinetic properties and is a promising candidate for tumour treatment. Furthermore, Roxyl-zhc-84 exhibited low toxicity, as evidenced by hemogram results in mouse experiments. Primary organs, including heart, liver, spleen, lung, kidney and brain, were barely affected, indicating that the Roxyl-zhc-84 exhibits only slight toxicity to the circulatory system and normal tissues (**Table [3](#T3){ref-type="table"}** and**Figure [S5](#SM0){ref-type="supplementary-material"}**).

Roxyl-zhc-84 induces apoptosis in both breast and ovarian cancer cell lines
---------------------------------------------------------------------------

Inhibition of HDAC induces programmed cell death. To understand the mechanism by which Roxyl-zhc-84 treatment inhibits cellular proliferation, we first tested its effect on apoptosis byinvestigate the function of Roxyl-zhc-84 in JAK1-STAT3-mediated drug resistance, we further assessed IC~50~ values of Roxyl-zhc-84 on JAK1 in an *in vitro* kinase assay. Roxyl-zhc-84 (0.1-1000 nM) inhibited the activity of recombinant human JAK1 dose-dependently and exerted additional JAK1 inhibitory activity at nanomolar concentrations (**Figure [5](#F5){ref-type="fig"}E**). Moreover, we predicted the binding model of Roxyl-zhc-84 in the ATP pocket of JAK1 by docking analysis (**Figure [5](#F5){ref-type="fig"}F**). Roxyl-zhc-84 tightly binds to the ATP-binding site of JAK1 in a binding mode similar to that of filgotinib. The fluorine atom of benzimidazole at proper locations forms a hydrogen bonding interaction with the LEU959 amide NH. Hydrogen bonds were also formed between the hydroxamic acid and the backbone residue of ASP1039 and 1042 carbonyl oxygen. This deep and close binding of Roxyl-zhc-84 to


may be responsible for well-tolerated observation during *in vivo* test and no significant loss of body weight, indicating that its toxicity is low. Roxyl-zhc-84 displayed prominent cytotoxic activity in various cancer cell lines with IC~50~ values in the 10-40 nM range, 30 times lower than that for the reference drug vorinostat.

To understand the mechanism of action of Roxyl-zhc-84 on cellular proliferation and HDAC targeting, we identified important mediators related to the HDAC pathway, such as the cell cycle and apoptosis. Roxyl-zhc-84 increased the level of acetylated histone H3, consistent with HDAC inhibition. We demonstrated that Roxyl-zhc-84 induced apoptosis in solid tumour cells, which reduced expression of the antiapoptotic protein BCL-2 and enhanced expression of cleavage of Ccleaved caspase-3. Additionally, as a target of HDAC, expression of p21 protein,vorinostat and abemaciclib are shown as positive controls. **(E-H)** Immunoblot of CDK4, CDK6, cyclin D1 expression and Rb phosphorylation in cell lysates. Cells were treated with Roxyl-zhc-84, vorinostat or abemaciclib. Data are shown as the mean ± s.d. \*p\<0.05, \*\*p\<0.01, \*\*\*p\<0.001.](thnov08p4995g006){#F3}

![**Roxyl-zhc-84 significantly inhibits growth of breast cancer in homograft and xenograft mouse models. (A)** Body weight curves of BALB/c mice in each group 1-32 days after injection (5 mice/group). Values were analysed using Igor Pro software. **(B)** Bioluminescence images of tumour-bearing mice. The 4T1-Fluc allograft model was treated with Roxyl-zhc-84, vorinostat (60 mg/kg) and abemaciclib (60 mg/kg) daily from tumour formation. **(C)** Histogram of firefly luciferase bioluminescence imaging in (B). **(D)** Tumour growth curve of 4T1-Fluc tumour-bearing mice in response to different treatments. **(E)** Survival curve of mice


lines. Data were acquired on GEO database (GSE53603, GSE27226). **(D)** Heatmap showing upregulated genes in the JAK-STAT3 pathway based on data from GSE53603. **(E)** Dose-response curve showing that Roxyl-zhc-84 (0.1 nM-1 µM) inhibits the activity of recombinant human JAK1 dose-dependently by *in vitro* kinase assay. **(F)** Representation of predicted binding modes of Roxyl-zhc-84 (purple) and filgotinib (green) in the ATP pocket of JAK1. Dash lines indicate H-bond interactions between compounds and JAK1. **(G)** Immunoblot of JAK-1 phosphorylation in MDA-MB-231 and MDA-MB-468 cell lysates. Cells were treated with Roxyl-zhc-84 at different concentrations. Vorinostat is shown as a negative control.](thnov08p4995g008){#F5}

![**Roxyl-zhc-84 significantly sensitizes tumours to treatment compared to synergy between HDACi and JAKi. (A)** Immunoblot of BCL-2 expression, Histone H3 acetylation and STAT3 phosphorylation in cell lysates. Cells were treated withbeating before pH drop (waveform freeze), and 2) flagellar quiescence in a cane-shaped form resembling those characteristic of Ca-induced quiescence (cane-shaped quiescence). The flagellum again began beating if the pH was raised to normal but eventually was disintegrated by tubule sliding if the pH was left lowered. Field-by-field analysis of the transient movement of flagella becoming quiescent upon pH drop demonstrated that the proximal bend of the cane-shaped form corresponded to the principal bend of the steady-state beating in some flagella, but in others, to the reverse bend. These observations indicate that low pHs affect flagellar beating by interfering with sliding-bending conversion by a mechanism different from that previously reported.


     }}
            ")}
        }}

        protected override bool CopyToFast(KeyValuePair<string, StringValues>[] array, int arrayIndex)
        {{
            if (arrayIndex < 0)
            {{
                return false;
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            {Each(loop.Headers.Where(header => header.Identifier != "ContentLength"), header => $@"
     return true;
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        {(loop.ClassName == "HttpResponseHeaders" ? $@"
        internal void CopyToFast(ref BufferWriter<PipeWriter> output)
        {{
            var tempBits = _bits | (_contentLength.HasValue ? {1L << 63}L : 0);
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                if ({header.TestTempBit()})
                {{ {(header.EnhancedSetter == false ? "" : $@"


            }}
                    tempBits &= ~{1L << header.Index}L;
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                {{
                    output.Write(new ReadOnlySpan<byte>(_headerBytes, {loop.Headers.First(x => x.Identifier == "ContentLength").BytesOffset}, {loop.Headers.First(x => x.Identifier == "ContentLength").BytesCount}));
     private unsafe void AppendNonPrimaryHeaders(byte* pKeyBytes, int keyLength, string value)
        {{
                var pUB = pKeyBytes;
                {AppendSwitch(loop.Headers.Where(h => !h.PrimaryHeader).GroupBy(x => x.Name.Length), loop.ClassName)}

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            public StringValues _"


Settlers from four major powers of the world have discovered new lands, with new resources and opportunities. Romans, Barbarians, Egyptians and Japanese all at once move there to expand the boundaries of their empires. They build new buildings to strengthen their economy, they found mines and fields to gather resources, and they build barracks and training grounds to train soldiers. Soon after they discover that this land is far too small for everybody, then the war begins...

Imperial Settlers is a card game that lets players lead one of the four factions and build empires by placing buildings, then sending workers to those buildings to acquire new resources and abilities. The game is played over five rounds during which players take various actions in order to explore new lands,The combination lock and valve herein illustrated is designed to enable the operator to determine the correct positioning of the valve actuator to effect opening and closing once the combination is known by the audible clicking of detents provided for this purpose, which detents also determine the open and closed positions of the valve parts, to stymie manipulation by an unauthorized operator to open the valve in the absence of knowing the proper combination and to simplify manufacture and installation. The audible clicking provides the advantage that the device may be manipulated without having to match indicia on a pointer or dial and so can be manipulated in uncertain light or darkness without the aid of a flashlight.


Duffy Dyer

Donald Robert "Duffy" Dyer (born August 15, 1945) is an American former professional baseball player who is currently the manager of the Kenosha Kingfish of the Northwoods League collegiate summer baseball league. He played in Major League Baseball as a catcher for the New York Mets (1968–1974), Pittsburgh Pirates (1975–1978), Montreal Expos (1979), and Detroit Tigers (1980–1981).

Playing career
Dyer was born in Dayton, Ohio. He was a three-sport athlete at Cortez High School in Phoenix, Arizona, and played collegiately at Arizona State University. Dyer played alongside Sal Bando and Rick Monday as a member of the Arizona State Sun Devils baseball team that won the 1965 College World Series. He was drafted by the Mets in the 1966 Major League Baseball draft and backed up Jerry Grote asQ:

What are the options for setting up a UNIX environment to learn C using Kernighan and Richie's The C Programming Language?

I'm a novice programmer and have been experimenting with Javascript, jQuery and PHP but felt I wasn't getting a real depth of understanding of what I was doing. So, after reading Joel Spolsky's response to a question on this site (which I can't find now!), I took it back to basics and read Charles Petzold's 'Code' and am about to move onto Kernighan and Richie's The C Programming Language. I want to learn this in a UNIX environment but only have access to a Windows system. I have Ubuntu 12.04 running on a virtualised machine via VMWare Player, and done some coding in the terminal.
Is using a


v. Dancing Bear Entertainment, Inc., 948 S.W.2d 185, 190-91[3] (Mo.App.1997). Always, "[t]he key to summary judgment is the undisputed right to judgment as a matter of law; not simply the absence of a fact question." ITT Commercial Fin. Corp. v. Mid-America Marine Supply Corp., 854 S.W.2d 371, 380[12] (Mo.banc 1993).
Review of an order granting summary judgment is essentially de novo. Id. at 376[4]. In reviewing summary judgments, appellate courts examine the record in the light most favorable to the party against whom judgment was entered. Id. at 376[1].
Point I:
Defendant's first point has multiple parts. Initially, Defendant argues that the trial court erred when it entered a summary judgment for Plaintiff and denied Defendant's motion for summary judgment "[b]ecause plaintiff was granted the Branson/Springfield Gray Line membership, as requireda condition precedent, because the condition was not impossible, but merely required the action of a third party to approve her membership."
To support its argument, Defendant relies heavily upon Juengel Constr. Co., Inc. v. Mt. Etna, Inc., 622 S.W.2d 510 (Mo.App.1981). Juengel discusses contract conditions that render a contract enforceable and those that make a contract unenforceable.

*866 "A condition precedent is an act or event that must be performed or occur, after the contract has been formed, before the contract becomes effective. Conditions precedent are disfavored, and contract provisions are construed as such only if unambiguous language so requires or they arise by necessary implication. The requirement in a contract of a third party's acquiescence or the performance of some act by him may or may not be


I have noted over the years wedding photos here featuring model Ts and always love to see them. Now that I have been invited to have my car involved in a wedding (friends daughter) I would love to see as many any wedding model T photos you have and hear of any ideas you may have seen or heard of.

I know Danial. My shoes are size 12. My Dad always told me my mouth was what was gonna keep me in trouble. And it seems like most of my life I've proved him right. But doggone it she's a good looking lady.

We were watching reruns of a great TV show last night called "Jerico". The Gerald McRaney character had a great line: "...son, I've been mayor of thistaken them to a special area where the groom wanted to have some pictures taken and then to the reception after we thought all the guest would be there. When you take the pictures that include the car some should be taken that give a good view of the entire car, just for future viewers that would like to know what the car looked like. Often the bride or the groom has chosen your car because they liked the car. They may like pictures of it with the newlyweds standing, or sitting, so they can be seen as well as most of the car.

We've used our Model T, Model A, and '42 Tudor as wedding cars for family and friends. Most wanted the cars in front of the


I use my 12 tourabout so weddings take a lot of brass polishing. If I know the kids getting married I usually do them for free. If I do I tell the groom that if he wants me to haul them at the wedding they will have to polish the brass and there is a lot of brass to polish on a 12. I also make if a practice to always tell them they must have a follow up car behind in case of car trouble.

Well, well... I usually leave very few electronic tracks on the internet, but this picture apparently "floats" around... It was a great day, as most weddings are. We even made a silent movie in black and white. I will try to upload it"Blake learned he'd been in custody of the North Koreans all that time, exposed to torture so intense, so prolonged that his conscious mind blacked it out." "The invasive nature of the surgery left him with permanent brain damage." "You should know, Sydney, that the National Security Council considers Blake a successful test case for neurostimulation therapy." "I'd consider death as an option before this procedure." "[Gunshots]" "[Sirens wailing]" "[Shouting in Spanish]" "You have been a busy man, Javier Parez." "Epidemiology lab in Cannes." "Disease-control ministry in Spain." "Genetic-engineering facility in Cuba." "Do I turn you over to Cuba, to Spain, to France?" "To me, there is no difference." "For you, there is at least one significant difference." "France and Spain do not believe in the death penalty."


success: function(result){
                    console.log(result);
                    }
                });
        }

To post the contents of a form to a php-page. But for some reason it doesn't seem to send this as a post. And it especially doesn't send it to the correct page.
What I end up with is this in the address bar:
orderlist.php?ID=36&SupStatus=2&OrderOther=Ska+binda+Telia+Liten+18+m%E5n.&Submit36=Spara
That's the name of the file where my AJAX-script is in. What it seems to be doing (to me) is that                         <option value='05'>Slutförd</option>
                            <option value='06'>Nekad</option>
                        </select>
                    ".$row['SupRealName']."
                    ".$row['Date']."


Relativity Space has confirmed that it has closed a $140 million Series C funding round. The company hopes to be the first to create an autonomous rocket factory capable of producing entirely 3D printed launch vehicles.

In an October 1 press release, Relativity Space confirmed the $140 million Series C funding round had been led by two new investors, Bond and Tribe Capital. In addition to a number of other traditional investors, the round also included funding from 30 Seconds to Mars vocalist turned movie star, Jardo Leto.

With this latest round of funding complete, the Los Angeles-based startup has raised $185 million. According to the company, the amount will be sufficient to complete the development of the Terran 1 launch vehicle and begin commercial operations by 2021.

“With the closeof our Series C funding, we are now one step closer to that vision by being fully funded to launch Terran 1 to orbit as the world’s first entirely 3D printed rocket,” said Cofounder and CEO of Relativity Space, Tim Ellis.

The Terran 1 vehicle is a 28-meter two-stage rocket capable of launching a 1,250-kilogram payload to low Earth orbit at a cost of around $10 million. The rocket is expected to be almost, if not entirely created from 3D-printed components. The components are printed using the company’s proprietary Stargate 3D printers. According to Relatively Space, with this technology, it will be able to go from raw materials to a completed Terran 1 launch vehicle within 60 days.

Relatively Space has already secured a deep reserve of launch contracts for


Resolution of transcription factors from a transcriptionally active whole-cell extract from yeast: purification of TFIIB, TBP, and RNA polymerase IIa.
We describe techniques for production and chromatographic fractionation of a transcriptionally active whole-cell extract from Saccharomyces cerevisiae. The procedure is suitable for large-scale isolation of the factors involved in mRNA synthesis. Both yeast transcription factor IIB and TATA-binding protein were purified from the extract as single species using an immunoblot assay. In addition, the three previously described isoforms of yeast RNA polymerase II were resolved and form IIa, the intact, unphosphorylated isoform proposed to be involved in initiation, was purified to apparent homogeneity.than $4 billion each year from purchases that are not made because customers found web sites too slow.”
The difficulty in maintaining an acceptable website response time is exacerbated during periods of unpredictable and dramatically changing traffic levels. In some cases, unusually high traffic levels can lead to outright website failure. This can be a financial disaster when the increase in traffic was the result of a successful and expensive advertising or promotional campaign undertaken by the e-business itself. For a brick and mortar business, an increased number of interested customers simply increases the length of cash-register lines. Eager customers seeing the long lines realize that the business is booming, and often decide to return later even if they are not interested enough to wait in line at that


afforded by the new lamps, we were able to do these much slimmer pixel LEDs," he explained.

"It basically has the effect of making the bonnet look longer, because your eye doesn't read a lamp going up the fender. And it also allows you to visually widen the car, and when the car comes towards you, you see the lights flow down and they pull your eye right out to the edges of the car. It's very, very important for a sports car particularly that it looks very, very planted and low at the front. So that's really what we're trying to do with that vehicle," Thomson said.

Those advances in lighting might be one of the most important technological changes affecting the way cars look these days. "When Ias ICU and CCU patients, and those discharging themselves against medical advice (if willing). However, relatives of deceased patients were excluded.

Provision was made for patients who might require reading assistance from other patients or "watchers" defined as relatives or domestic helpers. If the patient was a child, the responder was a parent or a "watcher".

To enhance anonymity, tracking of responders was discouraged. Thus patient\'s name and medical record number were omitted from the questionnaire. The survey began on 1st May 1993 and was closed on April 5, 1994.

Patients graded their satisfaction on a 4-point scale: poor=1; fair=2; good=3; and excellent=4 (Appendix). We considered ratings of poor and fair together as "dissatisfied". The results were analysed by SPSS PC+ statistical package.

We compared the numbers of dissatisfied patients between genders


training database constructed by deleting *Q* from the reference. The four reference databases used for CVI testing (BLAST16S/10, BLAST16S/10-V4, BLAST16S/10-V35 and WITS) contain a total of 136,178 sequences and L1O testing therefore naively requires executing a method on ∼10^5^ distinct test/training pairs, which is impractical for most methods with the computational resources available to a typical investigator. Storing the test/training data in FASTA format would require ∼1Tb, and while this data could be constructed on the fly, some methods require minutes or hours for training on a new database plus generating a prediction for one query, and the total execution time would be prohibitive. I therefore re-implemented RDP, Q1 and Q2_VS in USEARCH with optimizations enabling L1O in a single pass through the reference by masking out thethreshold used in the L1O testing reported in [@ref-51] and [@ref-12]. The same thresholds were used for SINTAX for comparison. GAST, MEGAN, PROTAX, 16Sclassifier, RaxML and pplacer were not tested due to implementation issues ([Supplemental Information 1](#supp-1){ref-type="supplementary-material"}).

10.7717/peerj.4652/table-2

###### Tested taxonomy prediction methods.

![](peerj-06-4652-g008)

  Method       Software            Algorithm reference
  ------------ ------------------- ---------------------
  BLCA         blca May 11, 2017   [@ref-58]
  BTOP         blastn v2.2.31+     [@ref-59]
  CT1          usearch v11.0       Re-implements Q1
  CT2


  --       --      --

**Notes:**

See main text for explanation of missing values.

Estimated numbers of novel OTUs from in vivo datasets
-----------------------------------------------------

The numbers of OTUs estimated to belong to novel taxa are shown in [Table 8](#table-8){ref-type="table"}. Similar results are obtained using BLAST16S/10, which has reduced sampling bias, and the RDP 16S training set, which has strong sampling bias similar to BLAST16S. These results suggest that reference set bias does not have a large effect on this task.

10.7717/peerj.4652/table-8

###### Numbers of OTUs estimated to belong to novel taxa.

![](peerj-06-4652-g014)

  Set                       Tag   Species
  Gut                       16S   --             222 (59.8%)    165 (44.5%)    49 (13.2%)     7 (1.9%)      0
  Mat                       16S   --             525 (78.6%)    454 (68.0%)    207 (31.0%)


with a named isolate because the isolate sequence will probably be present in the full Greengenes database but will be absent from the GG97 subset unless it is the chosen representative for a cluster. More generally, for sequences belonging to well-known genera, identity with GG97 will usually be lower than an unclustered authoritative reference which would enable more accurate predictions, noting e.g., that *Acc*~genus~ for the better methods on V4 falls from ∼100% to ∼50% as identity falls from 100% to 97%.

Toward realistic estimation of prediction accuracy
--------------------------------------------------

The TAXXI benchmark makes progress toward more realistic measurement of taxonomy prediction accuracy, while also demonstrating that a single metric cannot reliably predict performance on an arbitrary query set because identity distributions vary, and prediction performance varies with identity. Further development offor each value of *d* are needed for a robust measurement of variation). Second, calculating *P*-values from randomization alone would give a misleading impression of statistical power because I would expect changing the taxonomic bias of the reference database to change metric values at least as much as randomization. This could be verified by measuring variations by randomization and also with different biases, e.g., by comparing results between BLAST16S and BLAST16S/10, though ideally more than two cases would be tested. This is a challenging project which I deferred to future work. These issues underscore that while performance metrics obtained by the current implementation of TAXII are more realistic than previous benchmarks, they should be interpreted only as rough guides to performance in practice, and TAXII therefore cannot provide


began renovating certain hospitals in the country, including this hospital.

See also
 List of hospitals in Uganda

References

External links
Website of Uganda Ministry of Health
 Bundibugyo Hospital Cleaners lay down their tools for non-payment of wages

Category:Hospitals in Uganda
Category:Hospitals established in 1969
Category:1969 establishments in Uganda
Category:Bundibugyo District
Category:Western Region, Ugandaoverride {
    const uint32_t hash = HashSlice(key);
    return shard_[Shard(hash)].Lookup(key, hash);
  }
  void Release(Handle* handle) override {
    LRUHandle* h = reinterpret_cast<LRUHandle*>(handle);
    shard_[Shard(h->hash)].Release(handle);
  }
  void Erase(const Slice& key) override {
    const uint32_t hash = HashSlice(key);
    shard_[Shard(hash)].Erase(key, hash);
  }
  void* Value(Handle* handle) override {
    return reinterpret_cast<LRUHandle*>(handle)->value;
  }
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    mutex_lock l(id_mutex_);
    return ++(last_id_);
  }
  void Prune() override {
    for (int s = 0; s < kNumShards; s++) {
      shard_[s].Prune();
    }
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  size_t TotalCharge() const override {


were notified earlier [of the trial setting] at

the time it was reset.‖ He did not indicate that he had informed Mother and

Father of the trial setting. He said that he ―[had] not been able to have contact

with them [Mother and Father] in recent weeks‖ but that the ―last contact I had

with them was that they were still very much interested in defending their rights

and trying to at least maintain the best possible relationship with their children

and that their rights not be terminated.‖ When questioned by the trial court, the

Department indicated that it was in regular contact with Mother and Father during

their visitation with C.M.D. and H.M.A. and said that Mother and Father were

aware ―of this hearing today.‖ In fact, Mother and Father had visited the children

the Wednesday priorto trial.

                                         3
      The trial court granted Mother and Father’s attorney’s motion to withdraw

but denied the motion for continuance. The Department called three witnesses

whose combined testimony—including additional examination by the children’s

attorney ad litem—spans a mere thirty-six pages in the reporter’s record. The

trial court then granted the Department’s petition to terminate Mother’s and

Father’s parental rights and found that it was in the children’s best interest to do

so. The trial court signed a May 23, 2012 termination judgment immediately after

the Department presented its evidence.


further

deny all the allegations supporting the Department’s grounds for termination.

      3
        Counsel for the parties agreed and stipulated on the record at the motion
for new trial hearing that Mother’s and Father’s affidavits would be treated as if
they were attached to Mother and Father’s timely filed letter requesting a new
trial ―so that the Court of Appeals could consider the affidavits‖ and that the
affidavits would be treated as ―stipulated testimony for purposes of their Original
Motion for New Trial.‖

                                           We appreciate the policy concerns the Department identifies. It, the
      parent, and the child share an interest in a quick and final decision.
      In the Interest of M.S., 115 S.W.3d 534, 548 (Tex. 2003). But finality
      cannot trump a parent’s constitutional right to be heard. Stanley v.
      Illinois, 405 U.S. 645, 646, 92 S. Ct. 1208, 31 L.Ed.2d 551 (1972)
      (noting that ―the Constitution recognizes higher values than speed
      and efficiency‖). We have twice held that Family Code provisions
      that expedite termination proceedings must yield to due


  process. See In the Interest of B.G., 317 S.W.3d 250, 258 (Tex.
      2010) (holding that failure to file requisite statement of appellate
      points could not, consistent with due process, form a basis for
      denying parent an appellate record and that Family Code section
      263.405 was unconstitutional as applied to parent); In the Interest of
      J.O.A., 283 S.W.3d 336, 339, 347 (Tex. 2009) (holding that despite
      parents’ failure to file timely statement of appellate points, due
      process required that they be allowed to appeal complaining of
      ineffectiveRare times in local KT. Place your mouse over times and items for time conversions and info.

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I see what you mean, but I am not in that situation. But, someone might not be