adopted for the marketing was a ten-ounce bottle of unusual shape differing materially from the tall twelve-ounce bottle used for the marketing of beer. The Bevo cases were built to accommodate the shorter bottles.
"23. Sales of Bevo suffered drastic declines after 1918. From a volume of 10,449,152 dozen bottles in 1918, sales fell to 3,904,316 dozen bottles in 1919. Sales fell again from 3,044,006 dozen bottles in 1920 to 794,378 dozen bottles in 1921.
"24. The immediate cause of the decline of sales of Bevo after 1918 was a change, the effect of which was then being experienced, in governmental regulations under which breweries were thenceforth permitted to produce near-beer by the manufacture of alcoholic beer and its subsequent de-alcoholization, and to market such near-beer in ordinary twelve-ounce beerof the introduction of Ginger Ale, Grape Bouquet, Grape Concentrate and Carcho, there was no way in which the volume of production thereof, and the requirements of cases and bottles therefor, could be anticipated.
"31. Until the end of 1923, because of the reservation of the equipment for the marketing of other products, no effort was made by the management to sell supplies of empty cases and bottles excepting at prices comparing favorably with their costs or in instances where there were supplies of bottles without cases, the cases having been converted into beer cases.
"32. In 1923, Anheuser-Busch, Incorporated, was forced by competition to give *408 up using Bevo bottles for the purposes of marketing Ginger Ale and was compelled to adopt a different bottle for that purpose.
"33. In


matters fairly reflected their actual costs.
"44. The junk values assigned in the write-offs to said cases and bottles fairly represented their realizable values at the respective dates of the write-offs and were adequate.
"45. No physical deterioration can be attributed to glass bottles in storage and undisturbed, through aging or exposure for a period of not exceeding four years. Annual allowances for shrinkage in stocks of bottles are properly based upon breakage, abrasion and loss in the process of manufacture and in the hands of the trade, and *409 have no relation to bottles in storage. Therefore, it was proper, in making said write-offs, not to reduce the cost of the bottles by a depreciation or deterioration factor.
"46. Wooden boxes are subject to depreciation through aging and exposure, butbottles after said years and until they were ultimately sold, discarded, destroyed by fire, or otherwise disposed of. The schedule hereto attached contains a correct summary of the various lots of bottles and the character of the locations in which they were stored. (Schedule 4.)"
"XV. The evidence fails to disclose the depreciation and obsolescence sustained during previous years, the amounts charged off, or the amounts allowed by the Commissioner upon the particular equipment in controversy, but the evidence shows that depreciation was written off on all ten ounce cases and bottles: for the years 1916 and 1917, no depreciation; for the years 1918 and 1919 and the first seven months of 1920, 3.4¢ per case and 1¢ per dozen bottles shipped; and for the last five months of


$98,586.16 on account of obsolescence of the Bevo bottles which were the subject matter of the December 31, 1925, write-off. Such loss occurred in the year 1925, when the bottles became obsolete, and Anheuser-Busch, Incorporated, was entitled under Subsection (a) (7) of Section 234 of the Revenue Act of 1924, to deduct the amount of such loss from its taxable income for 1925.
"5. Under the facts and circumstances presented by the evidence, Anheuser-Busch, Incorporated, sustained a loss in the amount of $98,586.16 on account of loss of useful value of the Bevo bottles which were the subject matter of the December 31, 1925 write-off. Such loss occurred in the year 1925, when the bottles lost their useful value, and Anheuser-Busch, Incorporated, was entitled under the provisions of Subsection166 is set forth and applied in Real Estate Title Company v. United States, supra. Such regulations generally have the force of law, and when as here the statute does not descend to minutiae, but has been reenacted in view of the regulations, the interpretation by officials charged with administration may not be disturbed except for weighty reasons, and we perceive none as to these regulations. Brewster v. Gage, 280 U.S. 327, 336, 50 S.Ct. 115, 74 L.Ed. 457; Helvering v. Wilshire Oil Co., 308 U.S. 90, 60 S.Ct. 18, 84 L.Ed. 101; Helvering v. Reynolds Co., 306 U.S. 110, 115, 59 S.Ct. 423, 83 L.Ed. 536; Helvering v. Winmill, 305 U.S. 79, 83, 59 S.Ct. 45, 83 L.Ed. 52; Hadley Falls Trust Company v. United States, 1


in 1920 and 1921, from which time the sales fluctuated little until the end of 1925. The court found contributing causes of the decline in regulations that were established in 1916, two years before the mass of the equipment was acquired; in rising competition; in failure of prohibition enforcement; and finally the Bevo business was discontinued upon the repeal of prohibition. All of these were gradually operating factors except the last, and none of them operated to effect any great or definable obsolescence in the particular tax years in question. But the amount charged off in 1924, and claimed to be deductible, equalled at least 83 1/3 per cent of the cost of the equipment, and the element of depreciation considered in the charge off was only $74,987.70,as a result of the consolidation. *415 While it was known that two title plants would be acquired on the consolidation, there was at that time no definite plan for their disposition. But an immediate investigation was made and it was decided to store one of the plants in order to effect economies of operation. That was done substantially simultaneously with the consummation of the consolidation. About two months thereafter it was decided that the plant retained in use was adequate and that the one in storage would not be needed. Although for a brief period some slight use appears to have been made of the stored plant,[2] it was not kept up to date by the addition of current recordings. As a result it had only a


The selectivity of tyrosine 280 of human 11beta-hydroxysteroid dehydrogenase type 1 in inhibitor binding.
11beta-Hydroxysteroid dehydrogenase type 1 is a homodimer where the carboxyl terminus of one subunit covers the active site of the dimer partner. Based on the crystal structure with CHAPS, the carboxyl terminal tyrosine 280 (Y280) has been postulated to interact with the substrate/inhibitor at the binding pocket of the dimer partner. However, the co-crystal structure with carbenoxolone argues against this role. To clarify and reconcile these findings, here we report our mutagenesis data and demonstrate that Y280 is not involved in substrate binding but rather plays a selective role in inhibitor binding. The involvement of Y280 in inhibitor binding depends on the inhibitor chemical structure. While Y280 is not involved in the binding of carbenoxolone,criterion) and OS
--------------------------------------------------------

At the time of reporting the median follow-up was 9.7 months (range 3--19). Responders (CR/PR/SD *vs* PD) defined by any criterion had superior OS (by log rank testing); irRC *P*\<0.0001, RECIST *P*=0.0003, CHOI *P*=0.008 and mCHOI *P*=0.018, respectively.

Using irRC, the 6-month survival for responders *vs* non-responders was 100% *vs* 64% (95% CI 0.3--0.85) and 1-year survival was 85% (95% CI 0.48--0.97) *vs* 36% (95% CI 0.11--0.63), respectively. By RECIST 1.1, 6-month and 1-year OS for responders *vs* non-responders were 100% *vs* 78% (95% CI 0.51--0.91) and 100% *vs* 41% (95% CI 0.14--0.67), respectively. Using CHOI, the 6-month and 1-year OS were 95% (95% CI 71--99) *vs* 77% (95% CI 0.44--0.92) and 79% (95% CI 0.44--0.94) *vs* 52% (95% CI 0.22--0.75), respectively. Under mCHOI, 6-month and 1-year


survival were 100% *vs* 82% (95% CI 0.59--0.93) and 86% (95% CI 0.33--0.98) *vs* 63% (95% CI 0.39--0.8), respectively. Thus, response by each response criterion assessed here had independent prognostic value.

Discussion
==========

We performed a comparison of four radiological criteria in the assessment of response patterns in metastatic melanoma patients treated with pembrolizumab. There were differences in response according to location of metastatic disease and size of metastases. The majority of lesions showed stability over time with treatment rather than CR or PR. Nevertheless, there was a significant association with OS in all responders or benefiters from treatment (SD, PR and CR), by any response criterion, indicating a positive effect on overall disease control regardless of magnitude of tumour shrinkage. Responses tended to be early but 5% had a delayedfrom the private keys of the server. Should I be using this to generate some key for myself or?
I would ask the system admin directly but don't want to appear an idiot and waste everybody in-between us' time. Should I just ignore the key he sent me and ask them to put my public key inside their authorized folder?

A:

In my mind now what would happen is I would send them my public key which could be placed inside their authorized keys folder.

What's "in your mind" as what should now happen is correct.
Email is not a secure channel of communication, so from a standpoint of proper security, you (and they) should consider that private key compromised.
Depending on your technical skill and how diplomatic you want to be, you could


1. Field of the Invention
The present invention generally relates to a semiconductor device and more particularly, to a semiconductor device including an increase voltage generation circuit which generates an increased voltage greater than an externally-supplied power-supply voltage.
2. Description of the Related Art
Recently, in semiconductor devices, to reduce power consumption and to improve device reliability, a power-supply voltage has a tendency to decrease. Therefore, for example, in a semiconductor memory, a voltage difference between voltages for data 1 and 0 also decreases.
Now, for example, in a dynamic random access memory (referred to as DRAM, hereinafter) which is a kind of semiconductor memory, for a transistor for transmitting a memory cell (transmission transistor), an nMOS transistor is commonly used.
In such a DRAM, when logic information "1" is written into theto rats with unattached subcutaneous pumps. No analgesia was observed on tests of spontaneous pain or pressure hyperalgesia (p > 0.1). Conclusions. Intrathecally pumped saline and artificial CSF have analgesic effects on some neuropathic and normal, nociceptive pain signs in CCI rats.


friend of Bement's notified a municipal court employee of the comments the next day.

Today, he appeared before Cuyahoga County Common Pleas Judge Shirley Strickland Saffold having pleaded guilty to one count of attempted retaliation. Bement told Saffold that he was just venting and never intended for anybody to feel threatened.

"I was doing it for a shock factor," he said.

Assistant County Prosecutor Jim Hofelich said someone else could have read Bement's posting and acted on it.

Besides sentencing Bement to prison, Saffold also ordered him to receive anger- management and mental-health counseling.STOP. Before continuing, click here for important Internet security information about browsing this site.

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News & analysis from Proletarian Internationalist Notes—news, reviews and analysis from a global perspective

U.S. image and leader favorability in surveys: some underlying economic realities

According to the Pew Research Center, 83% of Swedish respondents in spring 2016 expressed either “a lot of confidence” or “some confidence” in “U.S. presidential candidate Hillary Clinton” “to do the right thing regarding world affairs.”(1) 0% of the Swedes expressed “a lot of confidence” for


who may be betting on people they don’t want to win as happens all the time in sports betting. Bets already reflect some consideration of the potential “silent majority” and social desirability bias issues being discussed in the media lately. With Clinton favored to win the presidency, it is necessary for anti-Amerikans everywhere to attack Clinton strongly regardless of Trump’s drawbacks perceived and real. If that is not true in terms of what WikiLeaks is doing now for example, it would be because anti-elite exposés have or acquire an undesirable populist character in the united $tates and Amerikans generally react in a bad way to such revelations because of their positions as oppressors or exploiters in the united $tates.

U.$. minorities and Amerikanism

In 2016, 83% of Pew Research CenterPrognostic Value of Lactate Dehydrogenase Expression in Different Cancers: A Meta-Analysis.
This meta-analysis was performed to elucidate the association between the expression of lactate dehydrogenase (LDH) and the prognosis of various malignant neoplasms. Qualified studies were systematically identified from relevant databases, including PubMed, Cochrane Library, Embase, WanFang, and HowNet. A total of 17 eligible studies with 4,176 patients that complied with the inclusion criteria were enrolled in this meta-analysis. The 17 articles were published from 2011 to 2018. The hazard ratio (HR) and 95% confidence interval (95%CI) were obtained from the selected studies. The analysis that included all LDH-related studies showed a significant association with the overall survival (OS) outcome (HR = 1.74, P = 0.001) but exhibited an insignificant association with the disease-free survival (DFS) or recurrence-free survival


"Maybe I'm not being clear enough." "Maybe I need to be honest with you and tell you what I want." "CHERYL:" "What is it that you want?" "I want your soul to open up for me." "Frustration or unhappiness are caused by the unrealized potential in a person." "Cyrenaic hedonism supported immediate gratification." "Even fleeting desires were encouraged regardless of the pain or expense to others." "QUAID:" "Can I bum a cigarette?" "Yeah." "I don't see you in any of the other philosophy lectures." "Ethics fulfills one of my requirements." "I'm actually a filmmaker." "Are you the real deal or someone who thinks he's the next Scorsese because he spent his Friday nights at the multiplex instead of getting laid?" "(CHUCKLES)" "I'm definitely not the next Scorsese, andI wasn't getting laid on Friday nights for reasons far more humiliating than being at the movies." "Quaid." "Stephen Grace." "Hey." "Hey." "(CAWING)" "QUAID:" "The philosophy major here is shit anyways." "What we should be doing is flirting with the subject of any worthwhile philosophy." "You know, the things we don't understand, the things we fear, because if we don't, then we risk..." "Doesn't matter." "We risk what?" "If you don't go out and find the beast, sooner or later, the beast will come and find you." "Well, I really don't think I have fears that justify a two-hour lecture." "No?" "What's the worst thing that's ever happened to you?" "My brother, my older brother, he died when I was 15." "How did he, uh..." "How did he


was 10." "On that day, I vowed to never have kids." "Can we stop?" "It turned out there was a worm, and it had crawled up there when I was swimming in the lake by my grandparents' house." "And my pubes, they started to grow this cheese." "(WATCH BEEPING)" "I think we have everything we need." "You know we've had five classes together." "Five." "And this is the first meal we've ever shared." "Well, it's not really a meal." "That's more like a botanical garden." "I'm sorry if I offend you with my roughage, Mr. Triple Bypass." "Mmm." "So good." "I just don't like meat." "Mmm, mmm..." "Mmm?" "Your burger..." "You want?" "...makes me want to vomit." "(LAUGHS) Gross." "That's lovely." "First meal." "Two years." "Yeah." "To besmall town in upstate New York." "My mom worked at the local supermarket, and my dad..." "And my dad worked at the..." "At a meat-packing plant about 20 miles outside of town." "They'd slaughter cattle there and supply our markets with corn-fed organic beef." "And he'd work late." "And by the time he'd get home, my mom would always be asleep." "I'd lay there on my pillow" "and listen to the sound of his boots walk to my bedroom door." "I don't know if my mother just pretended not to know what the fuck was going on or if she was just too weak." "You don't..." "You don't need to do this." "But, um..." "What I remember the most about it was the way..." "The way his flesh


deaf for three years." "So, I went from being, you know, a normal kid to being completely cut off from the world." "When it got really bad, I had a prayer." "My mom taught it to me." "It's, "Gentle Jesus..."" "Something..." ""Look upon this little child and..."" "(STAMMERING) You know, it was..." "It was that sort of thing, you know." "I can't remember it anymore." "Haven't needed it in a while." "(STAMMERING) Then one day, my hearing came back." "I mean, you know, I..." "Still, you know," "I hear any volume of sound, and the ringing comes back, and..." "Even talking about it, you know, it brings back" "a feeling of dread." "I mean, I suppose that is the worst part of it all." "You live with thealways ended up cursing me out whenever she had a confrontation with the meat." "Go to hell, fuckhead!" "Quaid!" "What are you doing?" "Why are you doing this?" "I'm not gonna do it." "I'm not gonna give you what you want." "I'm not even hungry anymore." "I'd rather die than eat your fucking meat." "About now she began to hallucinate." "Little mental ticks." "She'd think that she'd felt something in her hair or something on the back of her neck." "God, the meat looks..." "Ripe?" "It's warm in her little room." "And there's a few flies in there with her." "They found the meat and laid their eggs." "Was that a part of your plan, too?" "Yes." "Well, that's the crux of her dilemma, isn't it?" "The longer


   }

    ISpStartup();

    /* Get all the joysticks */
    numJoysticks = 0;
    for ( i=0; classes[i]; ++i ) {
        count = 0;
        err = ISpDevices_ExtractByClass(
            classes[i],
            MAX_JOYSTICKS-numJoysticks,
            &count,
            &SYS_Joysticks[numJoysticks]);
        numJoysticks += count;
    }

    for(i = 0; i < numJoysticks; i++)
               break;
            case kISpPadDownLeft:
                pos = SDL_HAT_LEFTDOWN;
                break;
        }
        if ( pos != joystick->hats[i] ) {
            SDL_PrivateJoystickHat(joystick, i, pos);
        }
    }

    for(i = 0; i < joystick->nballs; i++, j++)
    {


described above and which further has a polarity designating the desired mode of operation. The output of the integrator is essentially a ramp function which is applied to two comparator circuits which sense, respectively, positive and negative going ramp signals. When the ramp signal reaches a predetermined magnitude as determined by the comparator circuit, there is provided as an output signal a timing pulse which first serves to reset the integrator and which also serves, depending upon whether the timing pulse is from the positive or negative side of the system, to set a direction flip-flop the output of which provides the direction signal to a recirculating shift register. After a short delay to allow the direction flip-flop to set and apply direction signal to the recirculating shift2020-01-19T14:35:31+00:00

2020-01-19T14:35:31+00:00

2020-01-19T14:38:34+00:00.

Barcelona got a scare down the stretch but remained safe.

By Eurohoops Team/ info@eurohoops.net

Alex Abrines scored a season-high 18 points on 4/7 3-pointers in 21 minutes off the bench as Barcelona defeated Fuenlabrada 90 – 94 on the road to return to wins in the Spanish ACB League.

Fuenlabrada had fallen behind by 71 – 84 following a triple by Abrines three minutes into the fourth period until Marc Garcia scored 11 points out of his game-high 28 points in a row to cut the deficit to 86 – 88 and then 88 – 91 with 31 seconds left to play. Nikola Mirotic hit a key pair of free throws with the score 90 – 92 to secure the win of Barcelona.

Mirotic finished with 17 points plus seven rebounds while


completely different than the first. In fact, it'll be "focusing more on old English, equestrian and more sophisticated looks" than the flea-market-inspired first trip out the gate. Richie's shoe and accessory lines, meanwhile, will be ready for Spring 2010. [People]

The New Yorker sure knows how to give a bad restaurant review. Taking in the "sterile" and "unexuberant" fare at Armani's restaurant-within-a-store on Fifth Avenue, Lauren Collins writes: "At the bar, a manager and a bartender argued, loudly. The dispute seemed to be about a pen. Their passion did not extend to a pair of women who were waiting for a table, or, once the women were seated, to their full glasses of wine, paid for and awaiting transferral." [NYr]

A historic Christian Science church on Park Avenue took aHangman Books

Hangman Books is a British independent small press founded in 1981 by Billy Childish, who remains its owner and editor. It publishes poetry and some fiction. Associated projects are Hangman Films and Hangman Records.

Hangman Books has published poetry books and pamphlets by Billy Childish, Tracey Emin, Bill Lewis, Vic Templer, Joe Corkwell, Sexton Ming, Philip Absolon, Chris Broderick, Mark Lowe, Neil Sparks,  Louis-Ferdinand Celine, Dan Melchior, Dan Belton, Alfie Howard, Simon Robson, Steve Prince, Joe Machine, Wolf Howard and Amanda Collier, among others.

1982–87  the daily running of the press was carried out by Traci Emin (later Tracey Emin).  1988–99 it was managed by Kyra De Coninck (one of Thee Headcoatees band. Since 2000 Julie Hamper, Childish's wife,  has been overseeing it.

From 1986


This event is all ages

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This event is part of the 2017 HSL Properties Tucson Jazz Festival, January 12-22. For more information, visit tucsonjazzfestival.org.

“You could make the argument that if jazz is on the cusp of a renaissance, Kamasi Washington is its leader.” – Esquire Magazine

A concert with saxophonist Kamasi Washington offers serious jazz chops and a party spirit – see his latest Coachella outing or set at London’s Boiler Room as examples. The Los Angeles native bends sounds and genres while defying constraints and breaking boundaries.

Having collaborated with the contemporary likes of Kendrick Lamar, Flying Lotus and Ryan Adams, Washington blurs the boundaries between the generational divides of jazz, welcoming new and old purveyors alike while paying homage to the artists who paved the way.s(j) = -2*j + 10. Let v(t) = 5*p(t) - 6*s(t). Let r(g) = -3505*g**2. Calculate r(v(o)).
-14020*o**2
Let m(c) = 275*c**2. Let b(d) = 20389*d - 7*d**2 - 20389*d. Determine b(m(l)).
-529375*l**4
Let j(a) = 14*a. Let u = -190 - -192. Let g(t) = -9*t**2 + 5 + 3*t**u - 5. What is g(j(i))?
-1176*i**2
Let y(i) = 90*i**2. Let b(h) = 7 + 260*h - 7 - 140*h - 134*h. Calculate y(b(l)).
17640*l**2
Let y(z) = 5*z - 1. Let b(i) = 95*i**2 - 13*i - 3. Let r(p) = 729*p**2 - 104*p - 23. Let a(s) = 23*b(s) - 3*r(s). Calculate y(a(x)).
-10*x**2 + 65*x - 1
Let q(d) be the third derivative of 95 - 4/15*d**5 + 0*d + 0*d**3 + 0*d**4 + 2*d**2. Let u(r) = -14*r**2. Give u(q(g)).
-3584*g**4
Let g(m) = 4276*m.


was then placed in a cage with wooden chips and recorded for 1 h using a digital video camera. Afterwards, AniTracker® v1.2 was used to score the videos for the duration and frequency of grooming and scratching behavior. A scratching episode was defined as a bout of scratching by either hind paw; from the time point it was lifted until placed back on the ground. The videos were scored by observers blinded to the genotype and treatment given. The results for each group are expressed as the mean frequency of scratching episodes/60 min, the mean duration of scratching episodes/60 min, and, where relevant, as the mean length of scratching episodes (total duration/total frequency) and as the mean frequency of scratching episodes per each 10 min interval. Results are presented as mean ±lack of these two proteases, or if mMCP5-deficiency also played a role. mMCP5 is a mast cell elastase which has not been extensively studied and no connection to itch has been reported, but it has been shown to have a role in mediating epidermal burn injuries in mice \[[@CR56]\]. Since *Mcpt4*^*-/-*^*Mcpt6*^*-/-*^*Cpa3*^*-/-*^ mice lack CPA3, they also lose the ability to store the elastase mMCP5. To investigate the potential properties of mMCP5, the ET-1 test was also performed on *Cpa3*^*-/-*^ mice (that lack both CPA3 and mMCP5), to see if their scratching behavior would follow a similar pattern and magnitude as seen in *Cpa3*^*Y356L,E378A*^ mice (that possess mMCP5 but enzymatically non-functional CPA3) or *Mcpt4*^*-/-*^*Mcpt6*^*-/-*^*Cpa3*^*-/-*^ mice. However, the results from the *Cpa3*^*-/-*^ mice did not resemble the greatly enhanced scratching


Like any marriage, the $20 billion merger of MCI Communications Corp and British Telecommunications Plc may be smoothed by the experiences of a two-year courtship that preceded it.
"I may be an incurable romantic, but I think this is going to be a lot easier than people think," said one BT insider.
Concert, the name of the planned merged entity, was also the original name for a global communications offspring conceived by the two companies in July 1994 to provide one-stop shopping for multinational corporations.
While the executives atop the planned merged company have a clear vision of where they are going, insiders and industry sources say the acid test will be how the engine rooms of networks, billing, support and customer service are melded.
The initial partnership, now called Concert Communicationsaid.
Still, sources inside both companies believe the tough decisions have already been made, and a unified management can more easily resolve the remaining issues precisely because of the experience they already have in working together in Concert.
"Those debates by and large are behind us," said MCI Chief Engineering Officer Fred Briggs. "A unified management always shortens the decision-making process some," he added.
"It may sound weird, but you take out the need for cooperation. You can choose the best and discard the rest," TeleChoice's Briere said.
Concert Communications is already producing evidence of such a shift. The venture has $1.5 billion of revenue under contract and networks active in 800 cities in 50 countries. It has a head start over rival alliances Global One and Unisource, backed by Sprint Corp


to be identified.
But BT has never had to administer calling plans of the complexity of MCI's Friends and Family, which generates a high level of customer-service queries.
The two companies also plan to use Britain as a conduit to grab international business calling from continental Europe and route it through London to the United States.
Another major issue is what type of technology to use to bring Internet and multimedia applications to U.S. homes. BT is expected to be closely involved as a pioneer in so-called broadband technologies.
"That is going to be a major decision," MCI's Briggs said.     -- New York Newsroom 212 859 1610
challenges of infant care, little has been researched about the evolution of mother-infant sleep (both nighttime and daytime) and the progression from the early postpartum period to the later months, as infants\' sleep and metabolic circadian rhythms develop. The present study examines change in mother-infant sleep at six months as compared with two months postpartum.

It is well known that postpartum major depression is a serious illness, occurring in approximately 13% of mothers, that negatively affects both mother and child psychological adjustment in the long term \[[@B5]\]. Meta-analyses by Beck and Perkins \[[@B6]\] and by O\'Hara and Swain \[[@B5]\] examined multiple factors predicting postpartum depression. However, neither investigation reported any sleep-related variables. Similarly, Martini et al. \[[@B7]\] did not include sleep variables when examining depression and anxiety in peripartum


number of years they lived in Canada was 16.75 (SD = 13.64).

68% of the infants were male. Infants\' mean gestational age was 39.28 weeks (SD = 1.75). 84% of infants were breastfed a two months; 50% were still being breastfed at 6 months. 78% of infants were sleeping in the same room as the mother at two months; 41% of infants were still in mother\'s bedroom at six months.

3.2. Measures {#sec3.2}
-------------

### 3.2.1. Sleep Symptom Checklist (SSC) \[[@B11]\] {#sec3.2.1}

The SSC is a 21-item survey of a broad range of symptoms that are both directly and indirectly related to sleep disorders. Respondents rate each symptom, including poor sleep onset, poor sleep maintenance, waking too early, nonrefreshing sleep, and poor sleep quality, for its severity from 0 (not at all) toat two months and six months. No objective sleep data are reported. In addition, from the point of view of interpreting sleep problems and variations in anxiety and depression in these new mothers, it would have been useful to have examined prior habitual sleep and psychological adjustment.

One might hypothesize that the elevated scores in insomnia-related variables for a small segment of our sample reflect an intrinsic insomnia risk factor, which is triggered by the stresses of first-time motherhood. This hypothesis is supported by a recent qualitative study which evaluated sleep quality in a high risk for poor postpartum sleep sample, low income African American mothers \[[@B27]\]. To evaluate this hypothesis, one would need to carry out a prospective study, where a large sample of women are evaluated on


Bahadur Garh

Bahadur Garh is a town and union council of Dera Ghazi Khan District in the Punjab province of Pakistan. It is located at 30°13'30N 70°39'5E and has an altitude of 116 metres (383 feet).

References

Category:Populated places in Dera Ghazi Khan District
Category:Union councils of Dera Ghazi Khan Districtaxons by spatially loading Magic Red cathepsin B or L fluorogenic substrates (1:4,000 for 30 min) in the axon chamber ([Figure 5A](#F5){ref-type="fig"}). These substrates become fluorescent upon proteolytic cleavage by cathepsin B or L, respectively, within acidic lysosomes ([@R13]; [Figures S1C](#SD1){ref-type="supplementary-material"} and [S1D](#SD1){ref-type="supplementary-material"}). Live imaging revealed the presence of vesicular structures containing cleaved cathepsin B or L substrates along distal axons ([Figures 5A](#F5){ref-type="fig"} and [5C](#F5){ref-type="fig"}). To test whether cathepsin B- or L-mediated cleavage is dependent on acidic lysosomes, we monitored substrate degradation after blocking lysosomal acidification by using bafilomycin A (50 nM, 60 min), a vacuolar H^+^-pump (V-ATPase) inhibitor. Remarkably, bafilomycin A treatment largely suppressed cathepsin B- or L-mediated degradation along distal axons ([Figures 5A](#F5){ref-type="fig"}--[5D](#F5){ref-type="fig"}; [Videos S5](#SD6){ref-type="supplementary-material"}, [S6](#SD7){ref-type="supplementary-material"}, [S7](#SD8){ref-type="supplementary-material"}, and [S8](#SD9){ref-type="supplementary-material"}), indicating that lysosomal acidification is required for


cargos must travel from remote sites to the soma where mature lysosomes are relatively enriched ([@R16]; [@R29]). Axonal dystrophy and autophagic stress, indicators of impaired axonal transport or degradation capacity, are two hallmarks of major neurodegenerative diseases and LSDs ([@R75]; [@R44]; [@R69]; [@R76]; [@R64]; [@R78]; [@R5]; [@R23]). Thus, it is critical to assess the distribution, transport, and degradative capacity of lysosomes in distal axons. Here, we characterized enzymatically active lysosomes by using activity-based fluorescent probes that directly label active hydrolases, instead of using nonspecific endo-lysosomal markers, such as LAMP1/2 and lysotracker ([@R11]). Using the microfluidic culture system, our study provides direct evidence showing continuous delivery of soma-derived enzymatically active degradative lysosomes to distal axons, where they dynamically survey the axonal cytoplasm for degradation cargos to maintain axonal homeostasis.in distal axons rapidly mature into degradative autolysosomes that contain active lysosomal enzymes and degraded cargos, thus supporting the new concept that local degradation of autophagic cargos could occur before they are transported to the soma. It is likely that axonal autophagosomes can be removed by two pathways: either through their retrograde transport toward the soma ([@R39]; [@R10]) or through local degradation within degradative lysosomes in distal axons. As α-synuclein is a presynaptic axonal protein prone to aggregation, revealing that α-synuclein is targeted for axonal degradation within degradative lysosomes is especially important for advancing our understanding of the pathogenesis of Parkinson disease and other synucleinopathies.

Acidification of endocytic axonal organelles during their retrograde transport was previously reported using probes that were loaded to endosomes by endocytosis ([@R48]), a process


likely resulting in labeling of a variety of endocytic organelles from early and late endosomes to lysosomes, and thus, the observed increase in acidification likely reflects the transition from earlier endocytic organelles to acidic lysosomes. In the current study, we instead used activity-based probes that selectively label degradative lysosomes that can be delivered to and positioned along distal axons. It is technically challenging to assess local lysosome biogenesis by blocking lysosomal bidirectional transport, which would potentially impair local maturation of the endo-lysosomal system, and thus, we cannot exclude distal lysosome biogenesis. In light of the well-established contribution of retrograde transport of endo-lysosomes to the clearance of axonal cargos, both anterograde delivery of degradative lysosomes from the soma to distal axons, as well as the retrograde trafficking of endocytic-autophagicplating medium were added into the soma well of a microfluidic device and 20 μl plating medium was added into the axon well. After cells were attached to the main channel (10 min), wells were filled with plating medium (\~400 μl in total), such that axon wells contained more medium than soma wells to inhibit cells from crossing from the soma to axon compartment. Half of the medium was replaced with the same volume of NFM after 24 hours and at DIV4. Microfluidic devices were attached immediately before plating to dry 35-mm glass coverslips pre-coated with poly-ornithine (Sigma; 1:4 in PBS) and laminin (Roche; diluted 1:500 in PBS). For synaptic connected neuronal culture, cortical neurons were plated onto 12-mm coverslips coated with poly-orthinine (Sigma; 1:4 in PBS). After


GCase probe MDW941 (5 nM, 1 h) at DIV7-8, followed by 5-min time-lapse imaging with 1.3-s intervals to capture lysosome flux through axon bundles along the microgrooves (red box). The first frame and kymograph depicting the 5-min live imaging period are shown, where anterograde moving lysosomes are represented by slanted lines with a negative slope, retrograde moving ones by slanted lines with a positive slope, and stationary organelles by vertical lines.\
(B) A histogram of anterograde velocities of soma-labeled degradative lysosomes in distal axons. Data were collected from a total of 337 degradative lysosomes from 30 axon bundles in 3 independent experiments. The mean anterograde velocity (1.9 ± 0.04 μm/s) was measured from active GCase-labeled motile lysosomes with net displacement ≥ 10 μM.\
(C and D) Representative images (C) andagainst Arl8a/b or scrambled control (ctrl). Neurons were then incubated with MDW941 (100 nM) for 30 min priorto live-imaging at DIV3-4. Note that depleting Arl8 with either siRNA\#1 or siRNA\#2 consistently reduced the axonal density of degradative lysosomes (p \< 0.001), resulting in an increase in AV density in distal axons (p \< 0.001) under non-starvation conditions.\
(I and J) Axonal accumulation of mutant α-synuclein A53T caused by inhibiting the axonal delivery of degradative lysosomes. DRG neurons were co-nucleofected with α-synuclein-A53T-RFP and Arl8a/b-siRNA\#1 or scrambled control (ctrl-siRNA) at DIV0. Neurons were then incubated with BODIPY-FL-pepstatin A(1 μM) for 30 min prior to live-imaging at DIV3. Note that disrupting the axonal delivery of degradative lysosomes induces axonal accumulation of mutant α-synuclein.\
(K) Characterization of siRNA-resistant Arl8b mutant (R-Arl8b). R-Arl8b was generated


like experimental data and numerical simulations, so it is an equation-free algorithm. Its popularity is also due to the fact that it does not make any assumptions about the underlying system. See (Kutz et al. 2016) for a comprehensive overview of the algorithm and its connections to the Koopman-operator analysis, initiated in (Koopman 1931), along with examples in computational fluid dynamics.

In the last years many variants arose, such as multiresolution DMD, compressed DMD, forward backward DMD, and higher order DMD among others, in order to deal with noisy data, big dataset, or spurius data for example.

In the PyDMD package (“PyDMD: Python Dynamic Mode Decomposition. Available at: https://github.com/mathLab/PyDMD” n.d.) we implemented in Python the majority of thedynamical system. You can observe the sensible reduction of the noise.

Reconstruction

Acknowledgements

This work was partially supported by European Union Funding for Research and Innovation — Horizon 2020 Program — in the framework of European Research Council Executive Agency: H2020 ERC CoG 2015 AROMA-CFD project 681447 “Advanced Reduced Order Methods with Applications in Computational Fluid Dynamics” P.I. Gianluigi Rozza.

References

Koopman, Bernard O. 1931. “Hamiltonian Systems and Transformation in Hilbert Space.” Proceedings of the National Academy of Sciences 17 (5). National Acad Sciences:315–18.

Kutz, J Nathan, Steven L Brunton, Bingni W Brunton, and Joshua L Proctor. 2016. Dynamic Mode


Q:

React redux is not updating components

React app doesn't update components after reducing new state. After first render, no matter what actions i do, there is no updates in react components.
I tried to find some state mutation in reducers, but there are none. I have no idea what is a problem.
Here is repo: https://github.com/ithrasil/rainbeat/tree/bug
I would appreciate any help
one of reducers:
export default function(
state={
    received: false,
    status: false,
  primaryList: [],
  secondaryList: [],
  query: ""
},
action) {

switch(action.type) {

case "RECEIVE_STATUS":
  state.received = action.payload;
  break;

    case "SEARCH_STATUS":
        state.status = action.payload;
        break;

    case "PRIMARY_LIST_UPDATE":
     was to exercise “ordinary care in

maintaining the premises in a reasonably safe condition and has the duty to warn its

invitees of latent or hidden dangers.” Carlo v. Kohl’s Dept. Stores, Inc., 8th Dist.
Cuyahoga No. 105725, 2017-Ohio-8173, ¶ 8, citing Paschal v. Rite Aid Pharmacy, Inc.,

18 Ohio St.3d 203, 480 N.E.2d 474 (1985).

      {¶13}   “A premises owner is obligated to warn invitees of latent or concealed

dangers if the owner knows, or has reason to know, of hidden dangers.”       Id., citing

Rogers v. Sears, Roebuck & Co., 1st Dist. Hamilton No. C-010717, 2002-Ohio-3304.

Summary judgment may be granted “[w]here a hazard is not hidden from view or

concealed and is discoverable by ordinary inspection.” Id., citing Parsons v. Lawson

Co., 57


procedure

and could not be repaired with asphalt cold patch. Aspen also repaired several other small

potholes observed during the visit.

         {¶20}     Takacs explained that potholes can form and expand quickly due to

inclement weather including heavy rain and water accumulation. Potholes

also form or are impacted by temperature changes, traffic, landscaping operations, and

snow plows.

         {¶21}      Mitchell, a resident owner in the complex for about three years, met

Lacey while both were walking their dogs. On the day of the incident, Mitchell drove past

Lacey who was walking her dogs near the complex mailbox banks located shortly beyond

the community center.       Mitchell parked, exitedOhio Condominium Act.          In fact, a review of premises liability

cases against a condominium association and its managing agent involving business

invitees and the open-and-obvious defense reveals application of the doctrine to both

parties without a discussion of legal status.

       {¶43} Examples of such cases include:          Brandimarte v. Packard, 8th Dist.

Cuyahoga No. 67872, 1995 Ohio App. LEXIS 2095, 1 (May 18, 1995), finding that a

condominium association, its managing company, and cleaning company were entitled to

the protection of the open-and-obvious doctrine against a business invitee.        Hurst v.

Carriage House W. Condominium Owners Assn., 2017-Ohio-9236, 102 N.E.3d 1071 (6th

Dist.), finding that the condominium


thing for me and I haven’t been in far too long. I have some stuff I need to work through and I can’t fix all my problems via journaling.

Create a real manifestation board. I had one of these set up on my vanity mirror for a while, but had to take it down when we were showing the place to people. I’m going to set up one that can be moved from place to place and isn’t dependent on furniture.

Do another Good Things Jar for 2014. I did this in 2013 and it kept me going to see it full of pieces of paper, just covered in all the good things that had happened (even if they were as simple as “Still breathing”). I’m doing it again, andConvert.ChangeType(item.original, dt.Columns[item.columnName.Substring(item.tableName.Length + 1)].DataType);

shouldn't that be
DateTime.ParseExact(item.original, "dd/MM/yyyy HH:mm:ss:fff", null);

instead of
DateTime.ParseExact(item.original, "dd/MM/yyyy HH:mm:ss:FFF", null);

?

A:

In case anyone is wondering, the "solution" for this problem was to instantiate a DateTime object by deconstructing the string and assigning it on the DateTime constructor like this:
string[] date = item.original.Split(' ');
string[] datePart = date[0].Split('/');
string[] hourPart = date[1].Split(':');

DateTime newDateValue = DateTime.MinValue;

if (hourPart.Length == 3)
{
    newDateValue = new DateTime(Convert.ToInt32(datePart[2]), Convert.ToInt32(datePart[1]), Convert.ToInt32(datePart[0]), Convert.ToInt32(hourPart[0]), Convert.ToInt32(hourPart[1]), Convert.ToInt32(hourPart[2]));
}
if (hourPart.Length == 4)
{
    newDateValue = new DateTime(Convert.ToInt32(datePart[2]), Convert.ToInt32(datePart[1]), Convert.ToInt32(datePart[0]), Convert.ToInt32(hourPart[0]), Convert.ToInt32(hourPart[1]), Convert.ToInt32(hourPart[2]), Convert.ToInt32(hourPart[3]));
}

I say "solution" with quotes because I think that's a bad solution and there's probably a better way around it because this operation is relatively heavy but at least it works


something by date.” Here’s an example: “Individuals will be able to order books via our website by March 15th.” By distilling the intent down to its absolute simplest definition, we’ve obtained a statement short enough that everyone can keep it in mind throughout the next phase of development.

This statement is a context – not a commitment. A dozen words is clearly not enough to specify a product – but as you work through your list of ideas a mission statement can help solidify the line between what’s in this release and what’s out until future releases. It’s a very simple tool to help keep everyone on the same page and provide a context for the trade-offs every project needs to make at some point.

“But my project is more"unconventional war" led by opposition groups working in concert with criminal gangs. He said opposition claims government forces were responsible for launching tear gas at the maternity hospital were another attempt to demoralize a people who have "decided to break ties with the bourgeoisie forever."

Opposition members said they have no intention of easing up on protests.

"Twenty days of resistance and we feel newly born," opposition lawmaker Freddy Guevara said at an outdoor news conference Thursday as residents looking out from balconies in a
neighbourhood
at the heart of the protest movement cheered loudly in support.

The next planned protest is Saturday, when opponents are being asked to dress in white and march silently to commemorate the victims of the demonstration. Sit-ins to block major highways are planned for Monday.

General Motors announced


Maduro's removal before elections scheduled for late next year.

But the government hasn't backed down.

Already drawing criticism for the GM seizure, Maduro announced late Thursday that he wanted an investigation into cellphone operator Movistar for allegedly being part of the "coup-minded march" organized by his adversaries Wednesday. That march was the largest and most dramatic the country has seen in years. He said the subsidiary of Spain's Telefonica "sent millions of messages to users every two hours" in support of Wednesday's protests.

As tensions mount, the government is using its almost-complete control of Venezuela's institutions to pursue its opponents. On Wednesday alone, 565 protesters were arrested nationwide, according to Penal Forum, a local group that provides legal assistance to detainees. It said 334 remained in jail Thursday.I started getting same error for eclipse after installing QTP on my laptop.

when I tried to run a simple java hello world program from command prompt , I got below error :

c:\Java\test>javac MyFirstApp.java
Picked up JAVA_TOOL_OPTIONS: -agentlib:jvmhook
Picked up _JAVA_OPTIONS: -Xrunjvmhook -Xbootclasspath/a:C:\PROGRA~2\HP\QUICKT~1\bin\JAVA_S~1\classes;C:\PROGRA~2\HP\QUICKT~1\bin\JAVA_S~1\classes\jasmine.jar;C:\Users\vivekrs\Documents\Raj\sev2\Tools\
QTP11\QuickTest\MSI\bin\java_shared\bin
Error occurred during initialization of VM
Could not find agent library jvmhook on the library path, with error: %1 is not a valid Win32 application

Then I removed JAVA_TOOL_OPTIONS and _JAVA_OPTIONS variables from Environments and java and Eclipse both started working fine.

you can try type javac in cmd prompt and see what error you are getting, and try to resolve that error, elipse will start working.

First of all: I've just tried it with - well - almost the configuration you have (Win8-64bit), but with already a newer java and the SR2


Surfactant catabolism.
Alveolar pulmonary surfactant is a complex of macromolecular aggregates composed of phospholipids and surfactant proteins (SP) that is essential for maintenance of normal lung function. The importance of surfactant homeostasis is recognized in the patients and the animal models with pulmonary disease, although the mechanisms of surfactant homeostasis are not fully understood. In this review the author will discuss: (i) the mechanisms of the surfactant catabolism by macrophage and type II cells; and (ii) the important role of SP-D on ultrastructure of surfactant that affects uptake by type II cells.although I had the fire going, I killed it trying to get some briquets going as well and Jennifer had to salvage it. My manhood was also thrown in the fire, charred and left useless. We did however eat and it was all going so well…

Until out of the corner of my eye I see what looks like a cat but it’s a giant, and I mean, GIANT, raccoon! And it’s about 5 feet away, eye-balling the picnic table and our food. I chased him off and figured that would be the end of our friend but just minutes later he was back and even closer and after shushing him off, I turned around and the latern light fell on two of his buddies who were sneaking up


       for temp_arg in temp_args:

    ~/spark-2.3.1-bin-hadoop2.7/python/pyspark/sql/utils.py in deco(*a, **kw)
         61     def deco(*a, **kw):
         62         try:
    ---> 63             return f(*a, **kw)
         64         except py4j.protocol.Py4JJavaError as e:
         65             s = e.java_exception.toString()

    ~/spark-2.3.1-bin-hadoop2.7/python/lib/py4j-0.10.7-src.zip/py4j/protocol.py in get_return_value(answer, gateway_client, target_id, name)
  death penalty, had been prosecuted by the DA's office, had family members who had criminal records, or had previously sat on a jury that had returned a not guilty verdict in a felony case. These are all valid race-neutral reasons that are adequate to *682 justify a peremptory strike.[21] Barnes points to a white juror who was not struck and had a son who had been previously prosecuted by the DA's office, but this juror was not similarly situated with the African-American jurors who were struck. Five years before Barnes' trial, the white juror's son pled guilty as a first offender to criminal trespass and received twelve months probation. The African-American jurors who were struck due to criminal records had either been themselves prosecuted by the DA's office,


trial. We find no error.
8. Barnes claims that two prospective jurors, a corrections officer who was a former deputy and a fireman who was married to a police officer, should have been excused for cause due to their ties to law enforcement. Neither juror, however, was a sworn law officer with arrest power. Therefore, they were not subject to an excusal for cause on this basis.[28] We find no error.
*683 9. The trial court did not err by excusing a juror for cause due to her inability to fairly consider a death sentence.[29] "The proper standard for determining the disqualification of a prospective juror based upon his views on capital punishment `is whether the juror's views would prevent or substantially impair the performance of his duties as ato be brief but as complete as possible.
12. Barnes asserts that the state improperly commented on his pre-arrest silence in violation of Mallory v. State.[34] Specifically, Barnes complains that the prosecutor cross-examined Barnes about his failure to seek help after Barnes allegedly killed Wells in self-defense. The prosecutor inquired of Barnes why he had not flagged down a passing motorist or gone to the police. The state also argued this omission by Barnes in his closing argument.
In Mallory, the defendant was convicted of murder. The state introduced a portion of the defendant's statement that included a question about why the defendant, upon learning that he was under investigation by the police for the murder, had not come forward to explain his innocence.[35] We held on appeal that Georgia


that the admission of Brown's guilty plea was so prejudicial under the facts of this case that it amounted to errorsince Barnes was the admitted "triggerman" it was tantamount to endorsing a guilty verdict for Barnes. Barnes further complains that the state used the evidence of Brown's life sentence in the sentencing phase to argue that the jury should compare the sentences of the two men and find that the more culpable Barnes should receive death. At the start of the trial, the trial court denied Barnes' motion in limine to keep out any evidence of Brown's plea and sentence.
Under OCGA § 24-3-52, a non-testifying co-indictee's guilty plea is inadmissible at trial under the theory that it is not competent *685 proof of the defendant's guilt.[42] OCGA §"`should exercise broad discretion in allowing any evidence reasonably tending toward mitigation.'"[68] In fact, this Court has held that evidentiary rules may be trumped by a defendant's need to introduce mitigation evidence.[69]
In Georgia, mitigation evidence that relates to the individual defendant and not to the death penalty in general is admissible.[70] For example, evidence that concerns the defendant's guilt or innocence cannot be excluded by the trial court, even though a guilty verdict has already been rendered in the guilt/innocence phase.[71] The defendant's impaired "capacity to understand the cruelty of his acts" due to depression, poor impulse control, a troubled youth, and drug abuse is relevant at the sentencing phase.[72] It is reversible error to prevent a friend or relative of the defendant from taking the stand and


serious injuries, including brain damage and a loss of sight in her left eye.
The Court of Appeals in Vigue v. Noyes, 24 Ariz. App. 144, 536 P.2d 713 (1975) affirmed the trial court's entry of judgment N.O.V. as to the Gibsons, concluding that there was no evidence that the stable owners were negligent or were harboring a dangerous animal or knew of any dangerous propensities. The judgment in favor of Noyes, however, was set aside as the Court found there was a jury question as to whether he was negligent in leaving Whiskey unattended while he searched for his hackamore.
The possessor of a domestic animal other than a dog may be subject to liability under either a strict liability or negligence theory for harm caused by it tostiff front legs) causing his owner to slide off and allegedly acted "funny" on the day of the accident in no way tends to establish that Whiskey was vicious.
The question thus becomes whether Noyes may be subjected to liability on a negligence theory. Restatement of Torts § 518 states in part:
"LIABILITY FOR HARM DONE BY DOMESTIC ANIMALS WHICH ARE NOT ABNORMALLY DANGEROUS
"* * * [O]ne who possesses or harbors a domestic animal, which he does not have reason to know to be abnormally dangerous but which is likely to do harm unless controlled, is subject to liability for harm done by such animal if, but only if,
"(a) he fails to exercise reasonable care to confine or otherwise control it, and
"(b) the harm is of a sort which it


Winter 2016 Megamix

Detaljer

WINTER 2016 MEGAMIX

Curtain call for 2015 and introducing 2016 with the best of the best chart-hit-mixes assembled in a 72 minute mega-mix. 48 sizzling tunes from Adele, Calvin Harris, Major Lazer, Justin Bieber, Ellie Goulding, Martin Solveig, Robin Schulz, Macklemore and lots more …Uni-Vs-Al (Universal)
2003: Pushing It Hard
2005: The Funk Rocker
2006: Pushing It Harder: The Lost Tapes

DJ mixed compilations
2002: Club Mix USA (Tycoon Records/Sony Music Canada)
2004: Virgin Records Dance Hits (Virgin Records)
2007: High School Musical 2: Non-Stop Dance Party (Disney Records) [Remixed entire album & DJ mixed]
2008: Dance Anthems 2 (Thrive Records)
2009: Ultra.Dance, Vol. 10 (Ultra Music)
2009: Ultra Weekend 5 (Ultra Music)
2010: Jersey Shore Soundtrack (Universal Republic)

References

External links

αCharts.us entry

Category:1972 births
Category:Living people
Category:Remixers
Category:Record producers from California


in SNR and BER is due to the fact that, unlike classical IN mitigation methods, ANDL is implemented in the analog domain where the outliers are still broadband and distinguishable. Disproportional effect of the ANDL on the signal of interest and IN increases the SNR in the desired bandwidth by reducing the spectral density of the IN without significantly affecting the desired signal. The theoretical performance of the ANDL is validated via simulation of an OFDM-based system in IN environments. Moreover, we highlight the superiority of our approach over conventional techniques such as blanking, clipping, and linear filtering.

The remainder of this paper is organized as follows. Section \[sec:System Model\] describes the system and noise models. Section III presents the fundamentals of the ANDL along with matched filter modificationfilter. According to the basic concept of the proposed ANDL [@Alexi-Dale; @Khodam_Latincom], the time parameter $\tau(t)$ varies proportionally with the magnitude of the difference between input and output of the filter. Therefore, we have $$\label{eq:1st order CDL}
  \chi(t) = x(t) - \tau(|x(t)-\chi(t)|)\, \dot{\chi}(t)\,,$$ where $x(t)$ and $\chi(t)$ are the input and output of the filter, respectively, and $\dot{\chi}(t)$ denotes the first time derivative of $\chi(t)$. As shown in Fig. \[fig:Tau\_Orginal\], the time parameter ${\tau(t)= \tau(|x(t)-\chi(t)|)}$ is given by $$\label{eq:CDL tau}
  \tau(|x(t)-\chi(t)|)  = \tau_0 \times \left\{
  \begin{array}{cc}
    \!\! 1 &|x(t)-\chi(t)| \le \alpha(t)\\
    \!\!\frac{|x(t)-\chi(t)|}{\alpha(t)} & \mbox{otherwise}
  \end{array}\right.,$$ where $\tau_0$ is a fixed time constant and $\alpha(t)$ is the resolution parameter of the filter. The value of $\alpha(t)$ should be determined properly


13, what is 2c0 + 7?
2c7
In base 9, what is -1 - 446?
-447
In base 9, what is -508 + 1?
-507
In base 8, what is 65 - -11?
76
In base 2, what is 10 - 1101?
-1011
In base 13, what is 12c9 + -1?
12c8
In base 11, what is 0 - 309?
-309
In base 4, what is 1 - 220223?
-220222
In base 14, what is -2a5 + 3?
-2a2
In base 14, what is 55 + 4?
59
In base 16, what is -3 - 35f?
-362
In base 3, what is 220 - 10102?
-2112
In base 3, what is 2020 - -21?
2111
In base 13, what is 0 + -11?
-11
In base 6, what is -154 - -2?
-152
In base 10, what is 2 + 1234?
1236
In base 16, what is 5c + -9?
53
In base 4, what is -10 + 33322?
33312
In base 7, what// Jest Snapshot v1, https://goo.gl/fbAQLP

exports[`javascript classes invalid-class-declaration.src 1`] = `
Object {
  "body": Array [
    Object {
      "body": Object {
        "body": Array [],
        "loc": Object {
          "end": Object {
            "column": 8,
            "line": 1,
          },
          "start": Object {
            "column": 6,


       "column": 0,
          "line": 1,
        },
      },
      "range": Array [
        0,
        5,
      ],
      "type": "Keyword",
      "value": "class",
    },
    Object {
      "loc": Object {
        "end": Object {
          "column": 7,
          "line": 1,
       },
        "start": Object {
          "column": 6,
          "line": 1,
        },
      },
      "range": Array [
        6,
        7,
      ],
      "type": "Punctuator",
      "value": "{",
    },
    Object {
      "loc": Object {
        "end": Object {


  "loc": Object {
        "end": Object {
          "column": 9,
          "line": 1,
        },
        "start": Object {
          "column": 8,
          "line": 1,
        },
      },
      "range": Array [
        8,
        9,
      ],
      "type": "Punctuator",
effect) and regular versus non-regular post-intervention GE data (meditation effect). We constructed classifiers to distinguish between the baseline and post-intervention states ([Supplementary Methods](#sup1){ref-type="supplementary-material"}) and achieved prediction accuracies of 96% for the vacation effect (area under the receiver operating characteristic curve, or AUROC, equal to 0.98) and 85% for the meditation effect (AUROC=0.93; [Supplementary Figure S1](#sup1){ref-type="supplementary-material"}), supporting the potential for blood-based wellness biomarkers.

The molecular architecture of response to resort and meditation interventions
-----------------------------------------------------------------------------

To understand the molecular architecture of the relaxation and meditation GE signatures, we employed an integrative analysis strategy. GE traits from our study were used to construct a weighted coexpression network from which coherent modules of interconnected genes were identified ([Supplementary Table S4](#sup1){ref-type="supplementary-material"}). A broad range of biological processes, molecular functions, cell cycle pathways ([Supplementary Table S5](#sup1){ref-type="supplementary-material"}) and


for genes associated with AD processes. For example, the gene *MME* (a membrane metallo-endopeptoidase) was downregulated in the post-intervention time point relative to baseline. In the vacation subnetwork MME is linked to *NFIL3*, a gene found on activated T cells, natural killer cells and mast cells. Another interesting local network structure is centered around *CLU*, a gene shown to be involved in AD based on genome-wide association studies, with genes in the integrin family, involved in cell adhesion, clustered around CLU.

Similarly, of the 669 genes in the black, blue, salmon and tan modules that map to the Bayesian network, 508 are in the 836-gene meditation subnetwork, a 7.3-fold enrichment over what would be expected by chance (Fisher exact test *P*\<1e−300). For the meditation subnetwork ([Figure 3b](#fig3){ref-type="fig"}), the genescell senescence.

Biomarker results
-----------------

We scored several blood-based biomarkers to provide an integrated overview of biological aging as a short-term surrogate of the impacts vacation and meditation can have on wellness. Biomarkers such as telomerase activity and Aβ levels reflect cellular health, aging and stress.

### Telomerase activity

Baseline telomerase was lower in the regular meditators. The analysis of variance of group differences in change scores was marginally significant (*P*\<0.08; [Supplementary Table S9](#sup1){ref-type="supplementary-material"}). Day-5 follow-up *t*-tests showed a significant increase in telomerase activity only in the regular meditation group (*P*=0.004; [Supplementary Figure S3](#sup1){ref-type="supplementary-material"}).

### Aβ peptide levels

An analysis of variance of group differences in pre- to post-intervention changes in plasma Aβ40 levels was significant (*P*\<0.05; [Supplementary Table S9](#sup1){ref-type="supplementary-material"}). There were significant reductions in plasma Aβ40 levels in the vacation and novice meditator groups,


increase in the Aβ42/Aβ40 ratio. A growing number of human studies suggest that a low plasma Aβ42/Aβ40 ratio is a risk factor for major depression,^[@bib45],\ [@bib46]^ dementia^[@bib47]^ and higher mortality.^[@bib48]^ The Framingham Study also showed that increased plasma Aβ42:Aβ40 ratios are associated with decreased risk of AD and dementia.^[@bib13]^ Thus, the higher Aβ42/Aβ40 ratio observed in regular meditators at baseline and the increase in this ratio from pre- to post intervention in the novice meditator and vacation groups may be salutary to brain health.

The increase in the Aβ42/Aβ40 ratio (driven by a decrease in plasma Aβ40 levels) could also be related to the observed decrease in expression of *CLU* as part of the relaxation effect (*P=*0.00045). *CLU* is a confirmed AD gene from genome-wide association study, and encodesSetareh Moghadam and Louise Monte from UCSD and Lisa Pham from Capella Biosciences.

**Disclaimer**

The funders (Chopra Foundation, Benioff Foundation) had no role in data collection, analysis, decision to publish, or preparation of the manuscript

[Supplementary Information](#sup1){ref-type="supplementary-material"} accompanies the paper on the Translational Psychiatry website (http://www.nature.com/tp)

JL is a minor shareholder (\<\$10 K) in Telomere Diagnostics, a telomere measurement company that had no role in the current research. PYL is an employee of Capella Biosciences (a computational pharmaceutical company). ESE, EES and RET were past awardees of the Chopra Foundation\'s Rustrum Roy Award. The remaining authors declare no conflict of interest.

Supplementary Material {#sup1}
======================

######

Click here for additional data file.

######

Click here for additional data file.

######

Click here for additional data file.

######

Click here for additional data file.

######

Click here for additional data file.

![Study


Dollar General’s motion to
dismiss, citing Stokes’s claims as time-barred, and dismissed the case with
prejudice. The district court did not address or rule on Stokes’s motion to
amend. Stokes timely filed this appeal.
                                      II. ANALYSIS
       A.     Motion to Dismiss
       Dollar General filed a motion to dismiss or, in the alternative, a motion for
summary judgment. Stokes argues that the district court improperly granted
the motion.
       1. Standard of Review
                                      No. 09-60303

nonmovant’s favor.” Riverwood Int’l Corp. v. Employers Ins. of Wausau, 420 F.3d
378, 382 (5th Cir. 2005) (citation omitted).
       2. Title VII 90-Day Filing Period
       Title VII claims must be filed within 90 days of a plaintiff’s receipt of the
notice of right to sue or the action will be dismissed. 42 U.S.C. § 2000e-5(f)(1);
Taylor v. Books A Million, Inc., 296 F.3d 376, 379 (5th Cir. 2002), cert. denied,
537 U.S. 1200 (2003). The 90-day statutory period is strictly construed. Id.
Further, the 90-day period


    We disagree. As the district court correctly noted, the plain language of
the Determination states that Stokes “may only pursue the no cause issue by
filing suit . . . within 90 days of receipt . . . Otherwise, [her] right to sue will be
lost.” Stokes, therefore, was on notice that the 90-day period commenced upon
her receipt of the Determination. See St. Louis v. Tex. Worker’s Comp. Comm’n,
65 F.3d 43, 47 (5th Cir. 1995) (noting that one criteria to consider regarding
equitable tolling is whether the EEOC provided adequate notice of the
complainant’s right to sue) (citing Baldwin County Welcome Ctr. v. Brown, 466
U.S. 147, 151 (1984)). Moreover, her unsworn affidavit provides no information
regarding the details of her conversation with the EEOC investigator or whether
Stokes questioned the investigatorin 26.1 to 78.6% of the cases studied. Tobacco use and alcohol consumption were the main risk factors in young patients. Regarding tumor-node-metastasis stage, most studies found a predominance of cases diagnosed in early stages (I and II). The studies varied widely in terms of histologic grade of malignancy and locoregional recurrences. Regional lymph node metastases had a negative impact on overall and specific survival rates. Our findings suggest a lack of solid evidence of differences in the prognosis of oral squamous cell carcinoma between young and older patients. This may reflect variations in the samples studied, including the prevalence of risk factors, access to health care services, and time since diagnosis.


[Irradiation in radiodiagnosis: recent possibilities of decreasing the doses (author's transl)].
Depending on the film used, the new super-fast re-enforcing screens enable a four to six fold reduction in diagnosis cutaneous irradiation. This diagnosis irradiation which remains rather considerable under classical techniques, is frequently injustly neglected: the distribution of this new type of material seems desireable. On the contrary, the use of xeroradiography leads to an irradiation which is three times greater than in conventional techniques and fifteen times greater than in these new techniques: xeroradiography must therefore be reserved for very specific problems.succeed, it promises happiness to millions of living and millions of unborn people,” wrote Philip Beaver, a leader of the expedition.

Instead, as Billy G. Smith recounts, the pioneers fueled one of the most devastating plagues in Western history. The colonists toted water to their ship from streams on the African mainland, not knowing that the mosquitoes that bred in the water carried yellow fever.

When the cargo ship sailed off on further ventures, crisscrossing the Atlantic for six months, it brought yellow fever to dozens of ports in the West Indies, North America and Europe. Other ships had carried yellow fever, but not with such lethality: “Until the Hankey’s voyage in 1793, the concatenation of conditions that was to detonate the yellow fever bomb had never been present in


Over the past three years, there have also been reports of the Aedes albopictus, also known as the Asian tiger mosquito, in Los Angeles County. Public health officials are concerned that they could spread to other parts of the state.Earlier this year, the Daily Democratreported that experts in the west Sacramento area in California were evaluating a potential threat of West Nile Virus. Many dead birds were found and 18 tested positive for West Nile Virus. Additionally, 58 mosquito tests have also been positive for the disease. Though more intense in Sacramento County, West Nile Virus was also presenting in other areas. Yolo County had six dead birds and 19 mosquito samples that were infected. There was one human case that has been confirmed by the California Departmentto carry out secret work on to identify voices calling foreign embassies in Moscow.

‘Our Center was founded in 1990’, Koval explained to us. ‘Before that all of our employees worked in the applied acoustics unit — a department that was run by the KGB, but formally attached to the scientific development centre of the Ministry for Communications. Many of the people in the organisation were KGB employees – but I only worked freelance – and the State Security Committee paid 15% of the salaries. Of course it was strictly confidential work and we were not allowed to talk about what we were doing. The ‘Sharashka’, where Solzhenitsyn worked, was transferred from Moscow to St. Petersburg. The people described in his novel continued to work in the St. Petersburg


method in general provides a systematic formalism for describing the dynamics of observable, physical degrees of freedom in a theory with large $N$ symmetry. In gauge or matrix theory the physical observables are given by loops or traces of matrix products (words). The method then provides a direct change of variables to the invariant observables. The resulting effective or collective Hamiltonian describes the full dynamics of these invariants. The essential two terms that define the effective hamiltonian are the interaction terms containing joining and splitting of the loops. In ${\cal N}$=4 SUSY Yang-Mills gauge theory we follow the degrees of freedom consisting of the Higgs fields: $\phi_1 \phi_2 \cdot\cdot\cdot\,\phi_5, \phi_6$. In the proposal of Berenstein, Maldacena and Nastase two of the Higgs matrices $(\phi_5,\phi_6 )\,\,$ are chosen to\sum \, E_i A^{\dagger} (\{ l_i\} ) \, A ( \{l_i \} ).$$

The nonlinear transformation

$$\eqalign{A^{\dagger} ( \{ l_i \} ) &= \Phi^{\dagger} (\{ l_i \} ) + {1\over 4N}
\bar{C}
(\{ l_i \} , \{ l_j\}\{ l_k\} )
\Phi^{\dagger} (\{ l_j \} ) \, \Phi^{\dagger} (\{ l_k \} )\cr
&+ {1\over 2N} \, C (\{ l_j \} , \{ l_i \} \{ l_k \} ) \,
\Phi (\{ l_k\} ) \Phi^{\dagger} (\{ l_j\} )}$$

from coherent state fields $\, A (\{ l\} )\,$ to the physical collective fields relates the two representations. The coherent state picture will in the next section provide the simplest framework for incorporating the effect of Yang-Mills interactions.

We will start by considering the $g_{YM}^2$ effects of the dimensionally reduced Yang-Mills system and discuss simple, illustrative examples of corrections that this


non-triviality of the above comes from $Q_2$. We would expect the same to happen with the second string variables after seen in the third string in the case of $|V_{3}^{0}\rangle$. In this case we observe the necessity of the insertion $b^{(2)\dagger}_{J_1}$. Another factor comes from $b^{\dagger}$ which gives an insertion $b^{(3)\dagger}_{J_1-1}$. From we can easily read off the appropriate state for this term to be,

$$b^{(2) \dagger}_{J_1} b^{(3) \dagger}_{J_1-1}|V^3_0\rangle .$$

In exactly the same way we can argue for the following identifications

$$\eqalign{\Tr (P_1 A^{\dagger} b^{\dagger} Q_2) \longrightarrow  b^{(2)
\dagger}_{J_1} b^{(3) \dagger}_{J_1}|V^3_0\rangle  .}$$

The remaining terms follow

$$\eqalign{
\Tr (P_2b^{\dagger} A^{\dagger} Q_1)=\Tr (Q_1 P_2 b^{\dagger} A^{\dagger})
\longrightarrow & \,\,b^{(1) \dagger}_{0} b^{(3)
\dagger}_{J_1+J_2-1}|V^3_0\rangle \cr \Tr (P_2 A^{\dagger}b^{\dagger} Q_1)=\Tr
(b^{\dagger}Q_1 P_2 A^{\dagger}) \longrightarrow &
\,\, b^{(1) \dagger}_{0} b^{(3) \dagger}_{0}|V^3_0\rangle .}$$

Next we have the four remaining contributions. Consider

$$\eqalign{\Tr (b^{\dagger} A^{\dagger}Kernel" or "Reference Monitor." The use of such a mechanism was first described in "Computer Security Technology Planning Study," J. P. Anderson, ESD-TR-73-51, Vol. 1, AD-758 206, ESD/AFSC, Hanscom AFB, Bedford, Mass., October 1972. The security kernel approach is a method of building an operating system (the software that controls the execution of a computer) which is capable of enforcing DOD mandated controls on people's access to data. This approach has become to be accepted as one of the best techniques for providing computer security within a computing system.
In the reference entitled Building a Secure Computer System, M. Gassser, Van Nostrand Reinhold Company, New York, 1988, the security kernel is generally described as follows at pages 35-36:
The security kernel approach to building a system is based on the


from seeing information that it is not cleared for. The second rule prevents a subject from giving information that it is cleared for to another subject who is not cleared for it.
While security kernels dramatically improve the security of a computer system they do so at some performance cost. That is, consulting the access control database introduces extra computational steps for each operation. The performance degradation has generally been around 25%. That is, a trusted computer system with a security kernel is in general 25% slower than a comparable computer system without a security kernel. For many classified processing applications this degradation has been acceptable when compared with the damage to the national security from disclosure of the sensitive information. However, many applications require both computer security controlssustainable travel

You might think that healing and traveling are two separate activities that don’t naturally connect. However, these seemingly disparate things come together perfectly. Through travel, people not only have the opportunity to heal themselves, but the world as well. Travel can heal people personally through liberation and discovery. But it can also heal the world socially through cultural preservation, economic…

In October 2017, Travel+Social Good published a white paper enumerating the trends and tactics for bringing sustainable travel to the mainstream. TSG is a community of travel professionals committed to improving the world through tourism. Among the changemakers listed is Visit.org — a leader in technological innovation highlighting social issues through storytelling. Visit.org’s roster of professional ambassadors film, photograph, and write in-depth…

There are 370 million indigenous peoples living


  into_type(values & v)
        : into_type<row>(v.get_row()), v_(v)
    {}

    into_type(values & v, indicator & ind)
        : into_type<row>(v.get_row(), ind), v_(v)
    {}

    void clean_up() SOCI_OVERRIDE
    {
        v_.clean_up();
    }

private:
    values & v_;

    SOCI_NOT_COPYABLE(into_type)
};

// this is not supposed to be used - no support for bulk ORM
template <>
class into_type<std::vector<values> >
{
private:
    into_type();
};

} // namespace details

} // namespace soci

#endif // SOCI_VALUES_EXCHANGE_H_INCLUDED
In remote Uyghur province, Uighurs are under siege

Veiled women pass a statue of Chairman Mao in Kashgar, Xinjiang Province, China the day after the July 30 stabbing death of the ancient Silk Road city’s chief imam.

Ahmet raises a trembling hand to his face, taking off his glasses and wiping away tears. His voice quivers as he speaks, but not in sadness. He is afraid. Five days earlier, he was at his nephew’s house when security forces suddenly descended. The nephew had grown a beard. And in Xinjiang, the sprawling region that dominates China’s western flank and the locus of persistent civil strife, that’s often enough to put a man behind bars.

The nephew was taken away, as were his wife and their daughter, not yet a year old. When


mosques, airports, hospitals, schools and train stations across the region.

“I feel like I’m in a battlefield in Iraq,” says Fa Te, a 21-year-old Uighur resident of Urumqi. Soldiers are “everywhere.”

Some Muslims, like many of Xinjiang’s ethnic Chinese residents, support the crackdown. They argue that an iron fist is necessary to maintain safety.

But the extent of the repression and violence being employed raises troubling questions about whether the real goal is to contain “extremists” or simply to crush the Uighurs, a minority that fits uncomfortably into Beijing’s vision of a singular “Chinese dream.”

The government’s conduct in Xinjiang also poses new questions for an international community that has largely muted its criticism of China’s contentious human-rights practices in exchange for a smoother path to lucrative trade.

Are other nations, in theDARREN Osbourne is out of prison and back in Hollyoaks, and he’s a changed man, all quiet and humble. But things don’t go well when a shift at the Dog ends badly, then he gets a job at MOBS and is mugged of the takings on the way home. Steph is convinced he made off with the money himself.

Mercedes and Malachy are evicted, Warren has an admirer in Sasha and Steph tries to open her dance school.

Also, Nige makes a surprise appearance, Ste impresses a food critic dining at Il Gnosh and Spencer makes Warren sweat as he opens up to Calvin.


a composite number?
False
Is 10711501 composite?
False
Is 163514317 a composite number?
False
Is 289937 prime?
True
Is 4278797 a composite number?
True
Is 6594377 a composite number?
False
Is 9071633 a composite number?
False
Is 5090003 a composite number?
False
Is 76970087 a composite number?
False
Is 3582902 prime?
False
Is 412055447 composite?
False
Is 6838262 a composite number?
True
Is 648558733 composite?
False
Is 24649447 prime?
True
Is 222839057 a prime number?
False
Is 29961961 a prime number?
True
Is 25430813 prime?
True
Is 12033907 composite?
False
Is 21794827 a composite number?
False
Is 47303999 a composite number?
True
Is 29429063 composite?
True
Is 250235267 a composite number?
True
Is 33847349 a composite number?
False
Is 100558057 a prime number?
False
Is 13848859 prime?
True
Is 12520801 composite?
True
Is 57603281 a prime number?
True
Is 12708541 composite?
True
Is 6924401 prime?
False
Is 1050031 composite?
False
Is 55721507 composite?
True
Is 275263 prime?
True
Is 3798139 a prime number?
False
Is 10395613 composite?
False
Is 233871481 a composite number?
False
Is 65407106 a prime number?
False
Is 62732599 a composite number?
False
Is 1332553 a prime number?
True
Is 99185617 prime?
True
Is 382457 composite?
False
Is 144867007 a composite number?
True
Is 101137423 a primefrom the QRS complex by the use of some kind of filter when A-V block dose not exist, most of the Ta wave could be visualized. This, along with high fidelity recording techniques, may help detect atrial abnormalities in patients without A-V block. Future development of this equipment as a clinical tool is hoped for.


goal-to-game ratio.

Nicknamed "Bomber der Nation" ("the nation's Bomber") or simply "Der Bomber", Müller was named European Footballer of the Year in 1970. After a successful season at Bayern Munich, he scored ten goals at the 1970 FIFA World Cup for West Germany where he received the Golden Boot as top goalscorer. He scored four goals in the 1974 World Cup, including the winning goal in the final. Müller held the all-time goal-scoring record in the World Cup with 14 goals for 32 years. In 1999, Müller was ranked ninth in the European player of the Century election held by the International Federation of Football History & Statistics (IFFHS), and he was voted 13th in the IFFHS' World Player of the Century election. In 2004, Pelé named Müller incan censure her for leaving her baby. She could only have done as Mrs. Murphy did, give it the plain, coarse gruel, and watch it die, day by day, upon her lap.

Up to this time, but little has been said of Patrick Breen. He was an invalid during the winter of 1846 and ’47. A man of more than ordinary intelligence, a devout Catholic, a faithful and devoted father, his life furnishes a rare type of the pioneer Californian. To Mr. Breen we are indebted for the most faithful and authentic record of the days spent at the cabins. This record is in the form of a diary, in which the events of the day were briefly noted in the order of their occurrence. Lewis Keseberg kept a


with a knife or hatchet. The tripe, however, she cleaned carefully and hung on the outside of the cabin, on the end of a log, close to the ground. She knew that the snow would soon conceal this from view. She also laid away secretly, one teacupful of white beans, about half that quantity of rice, the same measure of dried apples, and a piece of bacon two inches square. She knew that if Christmas found them alive, they would be in a terribly destitute condition. She therefore resolved to lay these articles away, and give them to her starving children for a Christmas dinner. This was done. The joy and gladness of these poor little children knew no bounds when they saw the treasures unearthed and cookingPurington Shale

The Purington Shale is a geologic formation in Illinois. It preserves fossils dating back to the Carboniferous period.

See also

 List of fossiliferous stratigraphic units in Illinois

References

Category:Carboniferous Illinois
Category:Carboniferous southern paleotropical deposits


[sic] and immunities of citizens in the several States."

The second point is, that the U. S. constitution protects slavery, as property, in all the U. S. territories, and that neither congress, nor the people of the territories, nor any other power, can prohibit it, at any time prior to the formation of State constitutions.

This point is made, in order that the territories may safely be filled up with slaves, before the formation of State constitutions, and thereby to embarrass the free state (sentiment, and enhance the chances of slave constitutions being adopted.)

(The third point decided is that the voluntary bringing of Dred Scott into Illinois by his master, and holding him here a long time as a slave, did not operate his emancipation -- did not make himantigen-presenting cells and T cells, or be a source of specific armed cells able to fight early infection. Although maternally derived antibodies are generally considered to impair neonatal responsiveness to active vaccination, at least at the B-cell level, their potential positive effects on the generation of specific T-cell responses requires further detailed investigation ([@bib7]).

The rational design of the most appropriate maternal vaccination programmes and strategies is linked to a better understanding of the different mechanisms by which maternal immunity confers protection to the newborn. Veterinary models could help to address these fundamental questions for the benefit of human vaccination.


   width: calc(100% - 32px);
        }

        paper-tabs {
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            ></marked-element>
            </div>
          </div>
        </section>
      </iron-pages>
    `;
  }
  __selectedChanged(e) {
    this.selected = e.detail.value;
  }
  __contentChanged(e) {
    this.content = e.detail.value;
  }
  constructor() {
    super();
    this.selected = "0";
    this.layout = "0";
    this.content = "";
    this.cookies = true;
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  static


indicate what array we are operating on, we also write $A(i)=d$.

$D$ may an arbitrarily complex domain including composite data types and, recursively, arrays. It also stands for the basic building blocks such as integers, floats, and strings.

The matrix $M=\left( \begin{array}{cc}
    a & b \\
    c & d \end{array} \right)$ could be represented as a two-dimensional array as follows: $I=\{(0,0),(0,1),(1,0),(1,1)\}$, $A:\{(0,0)\to a,(0,1)\to b,(1,0)\to c,(1,1)\to d\}$, and $D=\{ a,b,c,d \}$. For individual elements, we also write $M(1,1)=d$.

The space of all arrays is denoted $\mathbb{A}$, the space of all indices is $\mathbb{I}$, and the space of all domains $\mathbb{D}$.

Using these definitions, an array database could be seen as:$$\mathrm{db}\subseteq\mathbb{A}$$

Using these ideas, we proceed to the definition of useful functions to work with arrays.

Functions {#sub:functions}
---------

We now definethe data item associated with an index entry is particularly large. In this case, the data item can be split up into two parts by duplicating the index and associating a part of the entry with every copy of the index. The separated items can be joined together using equi-joins which, due to the uniqueness of the index, are particularly cheap to execute.

Conclusion {#sec:conclusion}
==========

This paper presents an algebra for distributing and querying arrays. Since array operations tend to be complex and done in an external general purpose programming language, the algebra aims to take after the design principles of the relational algebra. We presented translations of relational concepts into the array world. Future work includes the implementation and evaluation of the concepts.

Acknowledgements {#sec:acknowledgements}
================

The author would like to thank


Hepatitis B is an infectious inflammatory illness of the liver caused by HBV. The disease has caused epidemics in parts of Asia and Africa, and hepatitis B is highly endemic in China. About a third of the world population has been infected with HBV at one point in their lives, and approximately 300 million people worldwide are chronically infected with HBV. Hepatitis B is a major global health problem and the most serious type of viral hepatitis as it puts people at high risk of death from cirrhosis of the liver and hepatocellular carcinoma.
A vaccine against hepatitis B has been available since 1982. The hepatitis B vaccine, which is made from inactivated HBV, is about 95% effective in preventing infection and its chronic consequences. Once infected with HBV,Pages

Monday, July 8, 2013

As the school year ended I had more than one parent ask me for some apps to add to their iPads to keep students learning this summer. I thought I would share some of the apps I came up with here. This is a mix of apps for students from grades 1 to 6.

If your child likes comic books there are a lot of them on the itunes store. Some are in French others aren't. Just look on the side of the page and look at languages. This will help you find out what language apps are listed in.

Another app to check out Educreation. It is free. Kids can watch lessons other teachers and students have created. They can also createthere own lessons on something


Welcome to the #6 of Nebulas Weekly Report, delivering developments in Nebulas projects.

Nebulas Weekly Report is maintained by Nebulas Developer Team.

Please send feedback to contact@nebulas.io, or @nebulasio on Twitter.

LAST WEEK’S News and Reports

Nov 25, Initiation of “NAS Token Bonus Program”

We are initiating the NAS Token Exchange Program with Bonus, for which a further 5 Million NAS tokens will be distributed to existing NAS token holders. To date there are 5 Million NAS tokens in circulation, fully distributed to accredited investors. These tokens make up 5% of the total amount of NAS tokens. Read project details.

After attending the Singapore Fintech Festival, the Nebulas Team returned to China with more programmes lined up. Nebulas Founder, Hitters Xu, subsequently spoke at a Beijing meetup and a lecture in Shanghai.

Nov 23, Beijing:like the way many of us host visiting friends. She recounts how she brought a group of colleagues for a walk on Manhattan’s High Line elevated park, with a break for wine in a friend’s garden apartment, followed by an intimate dinner at a small, favorite SoHo restaurant. She colored the walkabout with her own tips, anecdotes, and insights, inspiring them with an insider’s take on the Big Apple.

In effect, she’d taken them on her first Local Expeditions outing. An avid traveler herself, Blaine decided to venture into the tourism realm with a new kind of company that leads “anti-tours.” That is, she want- ed local residents to curate and steer their own expeditions based entirely on their own interests, passions, and unique expertise.

She came up with a


gardens (plus one dog park) she’s designed at sever- al boutique hotels in the neighborhood.

“To me that’s the best of Local Expeditions, when somebody can say, ‘I do this thing, and now am going to show you what it’s all about,’” explains Blaine. “And [Cole] is a really successful designer. She’s not talking about history; she’s not talking about anything except the work that she does. So I wouldn’t call hers a typical tour—it’s an expedition.”

New York, like many cities, requires a tour-guide license for indus- try professionals. Blaine says about 95 percent are her guides are licensed. However, she does not recruit guides, and encourages ama- teurs to join the Local Expeditions team and share their one-of-a-kind perspectives. If they’re not licensed, she’ll often help get themthe other side of the neighborhood or the other side of the globe. In a poetic turn, the company goal now applies to its founder.

“I think the biggest surprise for me is that the entire way I look at the city has changed,” she says. “It’s really quite remarkable, especially for somebody who’s been here 30 years. But I look at these buildings, and notice in photographs [that we use for social-media promotion] certain things I haven’t noticed—ever. I’ve always believed that the more you learn the history of something, the more you love it.

“[Through expeditions] I see things all the time that always existed, but are completely new to me. It opens my eyes even more to a great city with a huge past,” she says. “It’s


You are here

The European Southern Observatory announced that a two-year study of ten stars in the constellation Vela has resulted in the discovery of a treasure trove: more than 50 new exoplanets, 16 of which are super-Earths. One of them is believed to be in the "Goldilocks Zone" and could possibly sustain life.

The search for extraterrestrial life, especially sentient beings, gets a big boost every time astronomers find new planets. The more planets found, the more chances of finding an extraterrestrial "footprint," or signs that the planet may be inhabited. With telescopes like Kepler scanning the skies from space and the additional range and power afforded scientists through interferometry (the linking of radio telescopes to form one large telescope), the number of planets that scientists can study hasthat Mum would always have a ready supply of vests, pants and pyjamas in the spare room chest of drawers for her grandson and two younger granddaughters, just in case. I smile to myself when I stay over and find that these bedside drawers are still full of stickers, coloured pens and pencils, notebooks, hair slides and Molly Brett and other children’s books, even though her grandchildren are now well into their late teens and 20s. In Mum’s ailing mind, they are still children. I secretly love riffling about in the drawers and pinching the odd pack of unused crayons. There are three books that belonged to Mum as a child that I have my eye on – one about two penguins called Pen and Gwen. I feel


how will Mum and Dad deal with this latest news? The cost of more pretence, for the sake of those blessed ‘appearances’, will be increased isolation and zero offers of genuine support from those around them, as the truth becomes impossible to hide. Their instinct will be to resist and kindly refuse any support from professional care providers. And there is absolutely no way on this earth that either of them will consider going to anything like a memory café or support group – at least at this early ‘manageable’ stage. They are too proud (for that, read ‘ashamed’). Rescuers don’t have ‘needs’, remember. They learn, very early on in life, to lock them away – that others seem to matter and mean more.

Six days after Mum’s diagnosis,I’m already wondering whom they will tell, now that it’s formal. Now that the memory problem caterpillar has begun its slow but sure emergence into the Alzheimer’s butterfly. This is a form of butterfly unlike any other. It has none of the colour, grace or beauty of the aristocrat butterflies – the Peacock, the Red Admiral or the Painted Lady. Its wings are more akin to the raggedness of the comma, its texture more moth-rough. Yet in its uniqueness lies its tragedy. The life span of the Alzheimer’s butterfly is infinitely longer than most butterflies. Many seasons, rather than two or three. More autumnal decline and winter dormancy than spring birth, pupation and summer growth. That its population is also growing isn’t all good news.

Unfeigned joy was the


This request has been pending your approval for  56 days.  Please click http://itcapps.corp.enron.com/srrs/auth/emailLink.asp?ID=000000000057285&Page=Approval to review and act upon this request.

Request ID          : 000000000057285
Request Create Date : 8/30/01 5:59:30 PM
Requested For       : erik.simpson@enron.com
Resource Name       : Market Data Kobra NatGas
Resource Type       : Applicationsto one arena, the real point is something else entirely. Take for instance the scandal in the church, one minute it's about little boys and the next it's about tearing down the walls of power. Do you really think that this 'change of regimes' wasn't the whole point of this exercise in hysteria?

The argument that this is "abuse of power" is the same argument that justifies the claim that white people can't possibly be the target of hate crimes and that sexual harassment exists in the eyes of the beholder. A system of law that professes equal standing before the law can not accommodate such nonsense. Why change the Church? Why not, in the case of sexual misconduct, simply bypass it?

Think about it. The simplest solution to this


implicit faith that our small kindnesses matter. There may be places in the heart where my friend stands as an enemy before me but I have no wish to visit there prematurely. We must live faithfully in the aftermath of a brilliant September morning. We must continue in the belief that how we treat each other matters. Most especially, we must preach and practice the Word of God.

Friday, July 12, 2002

Yesterday, I outdid myself with the posting on Maria Goretti, so today I'll keep it fairly short...

Lately, I've been thinking a lot about what it means to live in a post-Christian world. I try to imagine a world in which the Incarnation never took place. Everything that we know, - the entire modern age, - is in somein classical crowdsourcing. This is already leading to early experiments such as expert-based crowdsourcing or solutions for task-injection across distributed social platforms. On the other hand, the design of such socially distributed computing structures relates the fields of crowdsourcing and human computation to the lessons from a broader class of collective intelligence platforms and applications.

The need to interrelate these fields is reflected in questions such as:

How can we design effective incentive systems for large-scale participation of human users in structured collective intelligence systems?

How do we design tasks at different levels of complexity that can be solved reliably through a composition of individual contributions?

How can we use intricate webs of social relationships of existing social platforms for new models of coordination in distributed task-solving?

How can distributed social media enable


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Life is complex. We all need help to navigate the challenges and major decisions of our lives. We all have blind spots and have made choices that have hindered our personal and professional effectiveness.and in a broader sense signal A/D multiplexing, switching, routing, grooming, wavelength conversion as discussed, for example, in the book entitled, “Optical Networks” by Rajiv Ramaswami and Kumar N. Sivarajan, Second Edition, Morgan Kaufmann Publishers, 2002.
SMF—Single Mode Fiber.
SML—Semiconductor Modulator/Laser.
SOA—Semiconductor Optical Amplifier.
SONET—Synchronous Optical Network.
SSC—Spot Size Converter, sometimes referred to as a mode adapter.
TDM—Time Division Multiplexing.
TEC—Thermo Electric Cooler.
TRxPIC—Monolithic Transceiver Photonic Integrated Circuit.
Tx—Transmitter, here in reference to optical channel transmitters.
TxPIC—Transmitter Photonic Integrated Circuit.
VOA—Variable Optical Attenuator.
WDM—Wavelength Division Multiplexing. As used herein, WDM includes Dense Wavelength Division Multiplexing (DWDM).
DWDM optical networks are deployed for transporting data in long haul networks, metropolitan area networks, and other optical communication applications. In a DWDM system, a plurality of different light wavelengths, representing signal channels, are transported or propagated along fiber links or along one more optical