Peer Influence on Eating Behavior in Overweight and Normal Weight Youths. Although most eating occurs in a social context, the effects of peer influence on child eating have not been the object of systematic experimental study. The proposed experiment assesses the effects of peers on food intake and food choices in overweight and normal weight youths. A mixed design with weight status, gender and peer's weight status as between factors and the social context (alone versus dyad) as within factor will be used to compare youths' food consumption when alone and when in the presence of a peer. The prediction is that both the social condition and the peer weight status will have an impact on overweight participants' food selection and food consumption. More specifically, overweight participants willNeuronal defects in genotyped dominant megacolon (Dom) mouse embryos, a model for Hirschsprung disease.
Dominant megacolon (Dom) is one of four mutations in the mouse which can produce a phenotype similar to Hirschsprung disease in man. Here, we report that it is possible to take advantage of two microsatellite markers to genotype Dom embryos and to study enteric neuronal development in Dom embryos using whole-mount immunohistochemistry. Dom embryos present a variable defect in the ileo-caecal region, as do embryos of other murine models of Hirschsprung disease.


Dosimetric audits of photon beams in radiation therapy centres in Rio de Janeiro, Brazil.
Data related to 11 y of high-energy photon radiotherapy beam dosimetry are presented and analysed. Dosimetric evaluations were carried out using water phantoms and thimble ionisation chambers and are part of the radiation protection regulatory licensing process for medicine facilities of Brazilian government. Measurements were done at reference conditions for a standard absorbed dose of 100 cGy [cGy (=1 rad)]. The absolute per cent deviation between the measured and presumed delivered doses should not exceed the tolerance level of +/-3%. The first dosimetry survey from 1996 to 1998 showed a situation that was an object of concern. Deviations of 22 and 18.7% could be measured, although small deviations were also obtained. After 1998, the improvementRed Bull team principal Christian Horner is against Michelin's plans to introduce 18-inch rims and more durable tyres in Formula One.

Michelin and current tyre supplier Pirelli are both in the running to be F1's sole supplier from 2017 to 2019 and are due to start commercial negotiations with Bernie Ecclestone before a final decision is confirmed by the FIA. Michelin's bid is dependent on being allowed to supply tyres on its own terms, but Horner doubts its plans would add anything to F1.

"An 18 inch rim and a one stop is going to do nothing for the spectacle of a grand prix," he said. "I think actually we need to be looking at doing the opposite: getting two- to three-stop races, controlled degradation, maybe more choice for the


Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness.
A mysterious respiratory illness with high mortality was recently reported in the southwestern United States. Serologic studies implicated the hantaviruses, rodent-borne RNA viruses usually associated elsewhere in the world with hemorrhagic fever with renal syndrome. A genetic detection assay amplified hantavirus-specific DNA fragments from RNA extracted from the tissues of patients and deer mice (Peromyscus maniculatus) caught at or near patient residences. Nucleotide sequence analysis revealed the associated virus to be a new hantavirus and provided a direct genetic link between infection in patients and rodents.justified! Parmita, bangalore, 2013-01-04 18:10:22.0

Why should beating 'anyone' be justified? Forget the law, beating wives, husbands, kids, servants or anyone in the household for that matter - what does it achieve? It achieves nothing other than releasing your own anger. The idea of controlling a woman with a cane is such a misled one! Back..

Why should beating 'anyone' be justified? Forget the law, beating wives, husbands, kids, servants or anyone in the household for that matter - what does it achieve? It achieves nothing other than releasing your own anger. The idea of controlling a woman with a cane is such a misled one! Sameer Paradia, mumbai, 2013-01-04 18:02:05.0

Not under any circumstances. Its against all the rules of humanity and culture. I feel it has to be dealt


672 F.3d 1209 (2012)
UNITED STATES of America, Plaintiff-Appellee,
v.
Jose ANTONIO-AGUSTA, also known as Ricardo Jose Artiaga, Defendant-Appellant.
No. 11-1008.
United States Court of Appeals, Tenth Circuit.
March 7, 2012.
*1210 Howard A. Pincus, Assistant Federal Public Defender (Raymond P. Moore, Federal Public Defender, with him on the briefs), Denver, CO, for Defendant-Appellant.
Ryan T. Bergsieker, Assistant United States Attorney (John F. Walsh, United States Attorney, with him on the brief), Denver, CO, for Plaintiff-Appellee.
Before MURPHY, HARTZ, and TYMKOVICH, Circuit Judges.
*1211 MURPHY, Circuit Judge.

I. Introduction
Jose Antonio-Agusta appeals the district court's application of U.S.S.G. § 2L1.2(b)(1)(A)(ii)'s sixteen-level sentence enhancement in calculating his advisory Guidelines range.[1] He argues the district court erred in relying on the indictment underlying his prior Arizona convictions to conclude those convictions constitute felony crimes of violence, warranting the enhancement. The district courtcharge the offense to which the defendant pleads, without the filing of any additional pleading." Finally, the judgment states Antonio-Agusta is guilty of:
OFFENSE: Counts 1, 2, and 3 Amended Aggravated Assault Class 3 felonies. A.R.S. [§] § 13-1203, 1204, 701, 702, 702.01, 801
Date of Offense: 06/07/2006
Non DangerousNon Repetitive

III. Discussion
This court reviews de novo a district court's interpretation of the Guidelines and its determination that a prior conviction is a crime of violence. United States v. Perez-Vargas, 414 F.3d 1282, 1284 (10th Cir.2005).[3]
U.S.S.G. § 2L1.2(b)(1)(A)(ii) requires the sentencing court to add sixteen levels to a defendant's offense level if the defendant was previously removed following a conviction for a felony that is a crime of violence. A crime of violence includes an "aggravated assault" and "any other offense under


law that has as an element the use, attempted use, or threatened use of physical force against the person of another." U.S.S.G. § 2L1.2, app. n.1 (B)(iii). Thus, the court applied the sixteen-level sentence enhancement for a crime of violence under U.S.S.G. § 2L1.2(b)(1)(A)(ii).
Antonio-Agusta does not dispute the indictment underlying his prior convictions reveals he was charged with three offenses that qualify as crimes of violence. Instead, he argues the district court erred by relying on the indictment to reach its conclusion because Arizona law makes clear the indictment is not reliable evidence of the elements of his prior convictions. In particular, he argues the indictment was not incorporated by reference in the judgment. He further argues the plea agreement and judgment amended the indictment, making it unclearit is unclear whether he pleaded guilty to the offenses as originally charged in the indictment and, therefore, the indictment is not reliable evidence of the elements of his prior convictions.
The first paragraph of each of the counts sets forth the offense with which Antonio-Agusta was charged. The second paragraph alleges the offense was committed in a dangerous manner, which would serve to enhance Antonio-Agusta's sentence under Ariz.Rev.Stat. Ann. § 13-604(P). See Montero v. Foreman, 204 Ariz. 378, 64 P.3d 206, 209 (App.2003). The enhancement set forth in § 13-604(P) is commonly referred to as an allegation of dangerousness. State v. Joyner, 215 Ariz. 134, 158 P.3d 263, 272 n. 10 (App.2007); Montero, 64 P.3d at 209.
*1215 In Montero, the Arizona Court of Appeals held that a plea


discovery that threatened to abolish love affairs…”

And love affairs weren’t offering much solace either, since they were greeted with such taboo when discovered.

But Fourier’s deep contribution wasn’t his critique, it was his obsessively detailed solution.He envisioned a world, a universe, even, centering on pleasure.It was a world that was half-born, waiting for us to both discover its presence and to make it real.In his vision, the planets are bisexual and make love to each other.All the animals have a pleasurable purpose in the grand scheme of things.The oceans taste like lemonade.

The rhythmic crash of lemonade waves is what anyone knows of Fourier these days, if they know him at all.It’s a point of absurdity used to dismiss him.Oceans of lemonade? Ridiculous! But of course, ridiculous, grand ambition iswere capable of was good.

Of particular interest, and why not?, was sexual pleasure.There were other pleasures, to be sure, but they were all eroticized, as were whatever duties we had.Work, for instance, would be communal, relational, and deeply sensual.Is your job drudgery?Well, make it pleasurable! Sexualize your strain and effort, and engage in it erotically with your co-workers!This might sound like a capitalism gone wild, but remember that Fourier’s work was to envision the entire world: if pleasure led to more pleasure, and everyone and every aspect of life were included, we’re engaging with a vision far too vast to be compared with simplistic promises of “love what you do” capitalism.

Sexual pleasure was everywhere, and Fourier wanted us to discover it.And not just one kind of sex.He supported


access to healthy and consensual sexual experiences is a human right.To this end, Charles Fourier wrote about a “sexual minimum.”Everyone should be assured sexual satisfaction in their lives to avoid corruption of everyday life and relationships.Since so many people are afraid of not getting laid, so much time and so many words are spent seeking sex.A culture that worked to guarantee a sexual minimum would remove many of the problems that arise in desperate pursuit.Relationships would be purified and clear.Countries wouldn’t go to war in a state of frustrated tension.Fourier suggested that the beautiful would have sex with the less beautiful, and that the less beautiful would be sexually honored for their beautiful features and traits.

If this sounds alarming, and your thoughts turn to sexual slavery or decadentthe 2 base region at the 3\' end of an intron and might lead to splicing changes; two genes, *RACGAP1* and *SPEG* on chromosome 7 contained a splice donor variant, a splice variant that changes the 2 base region at the 5\' end of an intron and can lead to splicing changes, as well. Furthermore, seventeen genes contained missense and according to SIFT prediction deleterious SNVs that might create partially or completely non-functional proteins. More specifically, *C16orf96* gene on chromosome 14, C4, *BFIV21, B-BTN2, TAP2* and *IL4I1* on chromosome 16*, IFIH1, LY75, SLC11A1, SLC38A11, SPEG, ZNF142, CCDC108, TTC21B, OBSL1, PTPRN, GLB1L* on chromosome 7 had missense deleterious SNVs. Several other genes contained SNVs with moderate impact. Details of genes containing splicing, 5′ UTR, both missense and UTR SNVs


data based on a large-scale causal network derived from the Ingenuity Knowledge Base. Then, IPA infers the most suitable pathways and networks based on their statistical significance, thus a threshold above which the pathways are significant is derived.

### Gene expression analysis {#Sec30}

Genes whose expression was studied included *CXCLi1* and *CXCLi2*. Total RNA from a caecal tonsil was isolated from four replicate control birds and eight replicate infected birds per line (6~1~ and N) using the RNeasy Mini Kit (Qiagen West Sussex, United Kingdom) following the manufacturer's instructions. For each gene, mRNA levels were quantified using TaqMan quantitative RT-PCR. Primers and probes for the 28S rRNA, *CXCLi1* and *CXCLi2* genes were as described previously \[[@CR78], [@CR79]\]. TaqMan assays were performed as described by Sutton et al. \[[@CR80]\]. Data waslength of the coding region of the gene

*EPHA5*

:   ephrin receptor A5

*GLB1L*

:   galactosidase, beta 1-like

GWAS

:   genome-wide association study

IBDV

:   infectious bursal disease virus

IBV

:   infectious bronchitis virus

*IFIH1*

:   interferon-induced helicase C domain-containing protein 1

*IL4I1*

:   interleukin 4 Induced 1

LD

:   linkage disequilibrium

*LY75*

:   lymphocyte antigen 75 precursor

MAF

:   minor allele frequency

MDV

:   Marek's disease virus

MHC

:   major histocompatibility complex

MSA

:   multidimensional scaling analysis

*NAT15*

:   N-acetyltransferase 15

*NRAMP1 (SLC11A1)*

:   natural resistance-associated macrophage protein 1

*OBSL1*

:   Obscurin-like 1

*PTPRN*

:   protein tyrosine phosphatase, receptor type, N

QTL

:   quantitative trait loci

*RACGAP1*

:   Rac GTPase-activating protein 1

*SLC38A11*

:   solute carrier family 38, member 11

SNP

:   single nucleotide polymorphism

SNV

:


Ted Cruz, Beto O'Rourke share how they're battling for Texas seat in US Senate Stakes couldn’t be higher in the fierce Texas battle between Cruz and O'Rourke.

In what is certainly one of the most closely watched midterm races in the country, the fierce Texas battle between incumbent Republican Sen. Ted Cruz and rising Democratic star Rep. Beto O’Rourke is consequential and surprisingly close.

The competition is so tight, the president stepped in on behalf of the senator he fought viciously against during the 2016 election. He called the man he once dubbed “Lyin’ Ted” a “friend” at a Houston rally Monday night. Trump added that “nobody has helped me more” in the Senate.

“Texas is a deeply red state, but it is changing and changing fast,” ABC News’ political directorfocused on being deeply Texas, even campaigning from inside a cattle stockyard to appeal to voters.

One voter, Maggie Wright, has been behind Cruz for years and even moved to Iowa during his 2016 presidential bid. In years past, she had her car wrapped in images of the senator and even got a billboard to support the senator.

“I love him because of his record,” Wright said. “He fought for our religious liberty, our Second Amendment right.”

Wright throws her support behind Cruz so strongly that, she said, when her husband asked her what she wanted for their 50th wedding anniversary, she told him: “I want Ted Cruz for president.”

And now, to the surprise of many, Cruz is aligning himself with Trump and appears to have let go of the bad


of final (except maybe the inner loop of case 2), but your cost estimates are way off.  We shouldn't expect a big effect anywhere because mt19937 is just plain slow and all 3 versions spend most of their time in it.

The only thing that's not lost / buried in noise / overhead is the effect of inlining int run_once() override final into the inner loop in FooPlus::run_multiple, which both Case 2 and Case 3 run.
But Case 1 can't inline Foo::run_once() into Foo::run_multiple(), so there's function-call overhead inside the inner loop, unlike the other 2 cases.
Case 2 has to call run_multiple repeatedly, but that's only once per 100 runs of run_once and has no measurable effect.

For all 3 cases, most of the time is spent dist(rng);, because std::mt19937%r15,%rsi
       mov    %r13,%rdx           # copy args from call-preserved regs
       callq  404d60              # mt PRNG for unsigned long
47.27% add    %eax,%ebp           # sum += run_once()
       add    $0xffffffff,%ebx    # --inner
       jne    .Linner            # }while(inner);
       mov    %ebp,0x4(%rsp)


Q:

Random samples from each column of a data.frame containing NAs

This is a follow up of this question. I want to draw random sample from each row of a data.frame independently from other rows. The data.frame may contains NAs as given in the given data.frame df.
set.seed(12345)
df1 <- c(rnorm(n=4, mean=0, sd=1), NA)
df2 <- rnorm(n=5, mean=10, sd=1)
df <- rbind(df1, df2)

t(apply(df, 1, sample, replace=TRUE))

         [,1]     [,2]       [,3]     [,4]    [,5]
df1 0.5855288       NA -0.1093033 0.709466      NA
df2 9.7238159 9.723816  8.1820440 9.723816 10.6301

From the first row I want to select four observations (non-empty columns) with replacement and from secondbut simply to say that this is something that I'm already putting a great deal of effort into. I think the large majority of the images posted are not objectionable individually. There may be a small number of seriously objectionable posts that I miss. This is inevitable; I can't spend several minutes on each image dissecting it, and even if I could, there would always be a small miss-click rate. This small number might still create an impression on the regulars; if it's only 2% of all images, that still comes out to 3 or 4 images per week at the current rate, which a user might see as a much more statistically significant trend than it actually is.
Beyond that, there are images that some users have complained


community that a stream of images of feminine characters creates. No individual image is objectifying in this way, as none of them are able to depict characteristics or story and exist only to be consumed. In the standard sense, this is really weird terminology which would seem to have us objectifying a character from an anime or illustration which is literally already an object to be consumed by us; it's hard to see how that is an issue if you don't look deeper.
But having many of these images together without any others may still have some effect on the perception of our community. Specifically, it may have the effect of associating us with the idea of objectifying women and leading to the inference that we are fans ofusers who don't know or care about anime will not have any interest in. Chat being the deepest level of the site, it should be the most biased in that way towards keeping the expert interested users around and active.
I don't think anyone will question that there's a definite correlation between people who appreciate the bot's output and people who have a strong interest in anime. So, in some sense, the bot is really doing a good thing here.
But that's only at a very surface level. While interest in the bot does correlate with anime expertise, it also correlates with all sorts of other spurious things that we don't really need. Female anime fans are probably less interested than male ones, and fans of genres like action or


(heterosexual) romance may feel left-out too.
I don't know whether the overall positive effect is bigger or smaller than the overall negative effect, or even if they're comparable. But we can keep most of the positive effects and get rid of the negative effects. These are real issues that we should try to solve and can make some progress with here, unlike the huge goal of ending objectification of women (which we're simply in no position to deal with on any real scale).
-
Getting rid of the bot isn't going to fix sexism in the world, or even in our chatroom. It isn't going to change our culture. Nor is it going to make more women interested in anime and manga as a whole.
And this isn't the headquarters ofmore this time than past primaries and past general elections,” said Bob Stein, a political science professor at Rice University.

“This is still a Republican state,” said Richard Longoria, a political science professor at the University of Texas Rio Grande Valley. “If he plans on winning, it is essential that he drives up vote totals in the Democratic parts of the state.”

In achieving that, O’Rourke acknowledged a bit of a different approach in the Valley,

“We’re very open,” O’Rourke said of his Valley strategy. “But I want the people of the Valley to drive the way that we campaign.”

O’Rourke didn’t have a strong South Texas performance in the March primary, so a bit of an adjustment is what political observers are watching for here. He captured just 51 percent of


Movie Review: Superman Returns

Outside the Dallas theater where my daughter and I were about to see a screening of the new Superman Returns, there was a stack of glossy tracts, posing the question, 'Who is the real Superman?' I think you can probably guess the answer to that. My daughter found the tract a bit silly, especially the ending where the reader is invited to check mark an acceptance of Jesus box and mail it in to receive 'free stuff.' Well, after sitting through the 150-minute film, I couldn't help but feel that I'd just witnessed an extended tract for a Jesus designed to appeal to a certain strain of contemporary culture.

And that's only one of the many problems with the new Superman film, directed by Bryan SingerUSA TODAY Sports

Ken Starr is no longer the Baylor president, but he is still defending the school and former football coach Art Briles for their handling of the sexual assault scandal that cost both Starr and Briles their jobs.

Speaking at the Texas Tribune Festival, Starr offered support for Briles, who was removed as coach in May after an investigation by the Pepper Hamilton law firm found the football program failed to adequately deal with student complaints accusing players of sexual assault.

“A grave injustice was done to Art Briles,” Starr said. “Coach Briles has been calumnied ... it’s completely unfair.”

Starr denied there was a larger issue for the university after two football players were found guilty of assaulting two students and another former player is indicted on a similar


void mousePressed(MouseEvent e) {
    // TODO Auto-generated method stub

}

@Override
public void mouseReleased(MouseEvent e) {
    // TODO Auto-generated method stub

}
         }

How will I make the ball stop moving when no buttons are being pressed?

A:

Under your keyReleased method, you should be able to do the opposite of your keyPressed method.  That is, if you press the right arrow key, add 1 to x_speed, and when you release it, subtract 1 from x_speed, using similar logic for the other keys.

close to the zipper foot as possible.✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄

Step 4: Iron the zipper teeth away from the fabrics and layer the fabrics again. ✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄

Step 5: Main fabric facing up, zipper (with the first piece sewn on) facing down and the lining facing down. Sew along the zipper, as close to the zipper foot as possible.

Iron the fabrics away from the teeth of the zipper and topstitch main fabric panels. Optional: If you are using trims add them now. We added ribbon 1.5" from the bottom of the purse. This is you can get creative!

✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄✄

Step 6: Open the zipper, place the two main fabric panels together and pin. (Optional: Iron the 2"X2" loop in half and then iron the raw edges toward the creased center line and fold again and press


basically “The Customer is King” and is the most important part of the production system. Without a consumer, there is no reason to produce. Therefore the question that the organization must ask itself is ‘what does the customer want or what does the customer thinks he needs or wants?’ To Deming, the only meaningful definition of quality is that which the consumer specifies. A product can be technically sound and cheap but if it is the wrong product, then it is worthless to the consumer. It is important to anticipate the consumer’s future needs as well as those of the present in order to continue to meet the consumer’s definition of quality and sustain a competitive advantage.

Deming looks at quality from a systems and leadership perspective. He hasGenetics of virulence of enteropathogenic E. coli.
Enteropathogenic E. coli (EPEC) are a major cause of diarrhea in infants throughout the world. Although this pathogen was described 50 years ago, it is only recently that the pathogenic mechanisms employed by this organism have been elucidated. The characteristic histopathology induced by this organism, called "attaching and effacing", consists of intimate adherence of the bacterium to the epithelial cell with marked cytoskeletal changes including effacement of microvilli. A 35 kb region of chromosomal DNA, called the LEE for locus of enterocyte effacement has recently been described which contains all known genes necessary for production of this characteristic histopathology. Within this region is the eae gene encoding intimin, a 94 kDa OMP involved in intimate adherence. Also within this region are genes


animal populations, shelters, and the developing world, access to vaccines is unreliable. Trying to fit all animals on the same kind of vaccine schedule can be unrealistic. It would be convenient if animals could be given all of their vaccines in one shot that would release the vaccines at predetermined times.

Engineers created a microparticle that resembled a cup and could be filled with specific doses of vaccine or medicine. The cups would biodegrade at predetermined rates, releasing their content into the bloodstream based on a schedule.The compound 2′,7′-dichlorofluorescin diacetate (H2DCF) was purchased from Calbiochem (La Jolla, CA, United States) and used as an H~2~O~2~-specific fluorescent probe at 50 mM (dissolved in 20 mM CaCl~2~).

Preparation of Rice Aleurone Layers
-----------------------------------

Aleurone layers were prepared from de-embryonated rice (*Oryza sativa* L.) grains as described previously ([@B61]). Firstly, the embryo and distal end were removed from the rice grains, and the embryoless half-grains were sterilized in 0.1% potassium solution for 10 min, and then rinsed with sterile water several times. Finally, the embryoless half-grains were imbibed in Petri dishes with double filter paper containing distilled water, and the dishes were placed into a 25°C constant temperature incubator for 48 h. Aleurone layers were isolated from the cultured grains by removing the starch endosperm. Thereafter, the isolated layers were


with 4 μL 5× PrimeScript Buffer 2, 1 μL RT Primer Mix, and 1 μL PrimeScript RT Enzyme Mix. qRT-PCR was performed using the SYBR Green real-time PCR Master Mix (TianGen, Beijing, China), following the manufacturer's instructions. The PCR Master Mix per reaction contained 9 μL of 20 × SYBR Green (containing 2.5 × Real Master Mix), 4 μL of cDNA, and 0.5 μL of each oligonucleotide primer. The PCR amplification was performed using the following primers: for EF-1α (GenBank Accession Number: [AA753281](AA753281)), forward 5′-ACGGCAAAACGACCAAGAAG-3′ and reverse 5′-CAAGAACGGTGATGTGGTATGG-3′, amplifying a 134-bp fragment; for HO-1 (GenBank Accession Number: [CA753857](CA753857)), forward 5′-TCAAGGAACAGGGTCACACAA-3′ and reverse 5′-CCTCCAGCCGTATGAGCAA-3′, amplifying a 142-bp fragment. The relative expression levels of HO-1 were presented as values relative to the corresponding control samples at 0 h, after normalizingdifferent to the Con treatment at *P* \< 0.05 according to Duncan's multiple test.](fpls-09-00084-g002){#F2}

To further determine whether endogenous H~2~O~2~ affects *HO-1* transcript expression of aleurone layers in response to drought stress, the cytosolic H~2~O~2~ levels were assessed. In this study, the aleurone layers treated for 24 h were labeled with the H~2~O~2~ fluorescence probe H2DCF-DA, and the fluorescence intensity of H~2~O~2~ was subsequently observed under LSCM (**Figures [2B](#F2){ref-type="fig"}--[O](#F2){ref-type="fig"}**). The H~2~O~2~ fluorescence intensity of the aleurone cells treated with PEG alone was significantly higher than those treated with distilled water (**Figures [2B,C](#F2){ref-type="fig"}**), indicating that drought stress significantly promoted the H~2~O~2~ production in aleurone cells. Surprisingly, the H~2~O~2~ fluorescence intensity of the aleurone cells treated with PEG + H~2~O~2~ was 25% lower than those treated with PEG alone (**Figures [2C,D](#F2){ref-type="fig"}**),


is a key signaling molecule involved in various physiological activities in plants, particularly protecting plant cells against abiotic stresses ([@B25]; [@B2]; [@B27]). Interestingly, due to the application of exogenous H~2~O~2~, the tolerance to abiotic stress including drought, salinity, and heavy metal salt, all of which caused elevated H~2~O~2~ levels, was enhanced in plants ([@B10]; [@B26]; [@B29]). In most cases, the involvement of exogeous H~2~O~2~ could increase the activities of the antioxidant enzymes CAT, SOD, APX, GPOX, DHAR, GR, and the levels of the antioxidants AsA and GSH, resulting in decreased levels of endogenous H~2~O~2~ in plants under drought stress ([@B32]; [@B40]; [@B29]). Furthermore, the investigations of [@B36] and [@B61] showed the beneficial role of HO-1 in soybean and rice subjected to drought stress. Importantly, the synergistic effects of[6](#F6){ref-type="fig"}**). This beneficial H~2~O~2~ effect was also observed by [@B48], who suggested that the exogenous addition of H~2~O~2~ reduces cellular damage caused by low temperatures, thereby increasing the survival rate. Therefore, it is crucial that the balance between the production and scavenging of H~2~O~2~ is precisely regulated by cell antioxidant machinery, which determines whether H~2~O~2~ acts as a signaling molecule delaying PCD, or as a toxic oxidative molecule promoting PCD.

As an endogenous secondary messenger, cyclic guanosine monophosphate (cGMP) is formed through guanylate cyclase (GC) catalysis and guanosine monophosphate (GTP) hydrolysis. H~2~O~2~ and NO contribute toward the increase in GC activity in plants ([@B17]; [@B47]). H~2~O~2~ plus the cGMP analog 8-Br-cGMP was found to delay PCD of the layers in response to drought stress, and the effect of cGMP-delayed


regulated flow rate is obtained from the vacuum source, as well as specialized knowledge as to how such rates optimize the particular mode of media being employed. The operation of conventional fluid sampling devices when applied to a conventional vacuum chamber to obtain a gas bag media sample also requires specialized knowledge as to how the fluid stream is properly directed to aspirate the gas bag media by differential pressure at a regulated rate according to standard operating procedures promulgated by governmental environmental regulatory bodies. Lastly, conventional fluid sampling methods often require a constituent sample media that has been employed for sampling to be returned to the laboratory for subsequent analysis. Often times the laboratory is at a great distance from the sampled source and postal shipping isDear Family, Friends, and Everyone Who Cares About Me,

I expect you are shocked to find me like this. Good! It is about time you have been shocked! It takes so much these days to rouse the bourgeoisie from its dolor. But rather than accept the universe is meaningless and things happen without reason, I expect you are looking deep inside yourselves for an answer. So let me oblige you by explaining myself.

I picked up my dry cleaning the other day. The bastards burned a hole right through my favorite shirt. On top of that, one of my pocket squares came back slightly discolored. Despondent, I tried to drown my sorrows in food, but my favorite restaurant overcooked my halibut. What kind of creature is your God, who allows


Q:

Searching for JS based (Highcharts, AnyChart, etc) thermometer or vertical linear gauge with multiple pointers

Despite combing the web, I have been unable to find an example to work from as a starting point. I am looking to recreate the thermometer gauge in the attached image using Highcharts, AnyChart, or similar JS based charting library. Any leads to examples would be much appreciated.
As you can see, the idea is to display multiple data values on a single thermometer or gauge in an intuitive and uncluttered way.

Thanks,
Baobab

A:

You can create that type of chart by using Highcharts. Use for example column series type and each segment can be a visible part of the column. To add the gradient colors easily, use color axis with stops. And finally, to add the pointers,[Research advancement in related genes of Ménière's disease].
Starting from rational bases for a genetic approach to Ménière's disease (MD), we explored the numerous reports published in literature and summarized the recent advances in understanding of the genetic fundaments of the disease. The research advances related to the genetic fundaments of MD were reviewed. The incidence of MD presents as familial clustering and hasdifference in geographical and racial, no certain gene associated with MD was found. At present, studies concentrate on those genes, such as human leukocyte antigen (HLA), DFNA9, chromosome 12, macrophage migration inhibitory factor(MIF), KCNE, and heat shock protein (HSP). However, there have much arguments in diagnose, classify and pathophysiology of MD, resulting in different conclusion and prospect. The characteristics of MD strongly suggest a certain role


reach for the package, the glinting point of his sword still leveled at her.

A different and even more desperate tack, then. She strove to keep the panic out of her voice. "Look, take the money, I wish you joy of it." Carcolf did not, in fact, wish him joy, she wished him rotten in his grave. "But we will both be far better off if you leave that package!"

His hand hovered. "Why, what's in it?"

"I don't know. I'm under orders not to open it!"

"Orders from who?"

Carcolf winced. "I don't know that either, but—"

Kurtis took the packet. Of course he did. He was an idiot, but not so much of an idiot as that. He snatched up the packet and ran. Of course he ran. When didn't he?

He torefleshy woman with dark curls spilling from beneath a purple cap, small eyeglasses that made her eyes seem large, and a smell about her of lamp oil. She haunted the anteroom before the Quarryman's office at a low desk stacked with ledgers. On Friendly's first day, she had gestured toward the ornate door behind her and said, "I am the Quarryman's right hand. He is never to be disturbed. _Never_. You speak to me."

Friendly, of course, knew as soon as he saw her mastery of the numbers in those books that there was no one in the office and that Borfero _was_ the Quarryman, but she seemed so pleased with the deception that he was happy to play along. Friendly had never liked to rock boats unnecessarily. That's


creaks all night long," she said. "I mean, it almost moans. It shouldn't. Everything inside is new. Miles's door slams at strange times. And he... he's getting worse. It's like something has settled on him. A darkness he carries on his back. Like an insect shell. He scuttles. Like a beetle. I'd move, that's how scared I am, I'd move, but we don't have the money. Anymore. We spent so much on this house, and then almost that much renovating, and... my husband won't let me anyway. He says Miles is just going through growing pains. And that I'm a nervous, silly woman."

"I can help you," I said.

"Let me give you the whole tour," she replied.

We walked down the long, narrow hall. The house was naturally dark. Youthe Elephant for the gorgeous artificer. And for you, Your Grace, a Peril on the Sea and a Rise and Fall of Empires."

Amarelle hefted the latter, a thick glass containing nine horizontal layers of rose-tinted liquors, each layer inhabited by a moving landscape. These varied from fallow hills and fields at the bottom to great cities in the middle layers to a ruin-dotted waste on high, topped by clouds of foam.

"Anyone heard from Jade?" she said.

"Same as always," said Shraplin. "Regards, and don't wait up."

"Regards and don't wait up," muttered Amarelle. She looked around the table, saw mismatched eyes and shaded eyes and cold black stones fixed on her in expectation. As always. So be it. She raised her glass, and they did likewise.

"Here's a toast," she said.


a set of footsteps stopped long enough for an eyeball to appear in the small window that served as a peephole.

The door didn't open. "Who's there?"

He assumed his most polite pose, hands folded in front of himself, slight stoop to minimize his prodigious height. "Pardon me, ma'am—but I'm looking for Ammaw Pete. Would that be you?"

"What's it to you?"

"I'm Kilgore Jones. We spoke on the phone this morning," he told her.

"That's right, I recall. You're a big son of a bitch, aren't you?"

"That's what they tell me."

"What is it you do again? You're not with the po-po, I remember that much."

"I'm a machine-shop worker from Chattanooga."

The eyeball narrowed. "And investigator of the occasional drowning...?"

"Not the drowning, ma'am. The thing what caused it."

He heard a click, the twist ofBut he was clearly lying. Shortly afterwards I had the pleasure of receiving a surprise visit at my office from His Grace the Earl Marischal, the Duke of Norfolk, on official business as officer of arms at the College of Heralds. He told me that a thousand guineas had gone missing from the College's account at Cuits."

He had taken exactly the right amount of money. Hamilton felt perversely annoyed at the association between the boy's amateurishness and himself. "Did Precious do that for him?" The Herald hadn't seemed capable of such foolishness. Was his younger self really that alluring? It was too tempting a thought to be true.

"Perhaps it was done with information from her, but without her knowledge," said Turpin. "His Grace also informed me that the


stopped making them, so you don't see these very often."

"Are they valuable?"

He snorted. "No more valuable than any other shekel of the same weight. If anything, less valuable. Who wants a Melkart with no nose in his coin purse?"

While he continued to fondle the coins, doting over them like a boy with toy soldiers, I took a closer look at the so-called Books of Secret Wisdom. I chanced to pull out a scroll that gave instructions for changing men into women, and vice versa. This was a subject with which I had some acquaintance, having witnessed such an alleged transformation at the sacred spring of Salmacis in Halicarnassus. I was scanning the text to see if it mentioned Salmacis, when I realized that Kerynis had leaned forward, bringingof the grave—it was the only way." She spoke with simple conviction, but it was like hearing a hymn of praise to some ancient and long-forgotten god. I had found the notes in her sketchbook peculiar enough, but I was struck now even more forcibly by the distance between her way of thinking and my own. We might have belonged to two different races, indoctrinated into different belief systems. It seemed to me there was something almost inhuman about her.

It left me speechless, but Jesperson's face was alight with curiosity as he asked, "Weren't you frightened?"

"Oh, yes! Certainly! Terrified!" She gave a nervous laugh and no longer looked like anything but a pretty, modern, ordinary girl. "Never so frightened in all my... But then that was part of


the candle in front of her at eye level. _Everything is off here_ , thought the Marquis, and he realized he should have been listening to her from the beginning. _Everything is wrong_. He said, "Who are your people, Knibbs? Where do you come from?"

"Somewhere you ain't welcome anymore," said the girl. "I was born and bred to give my fealty and loyalty to the Elephant and the Castle."

Something hard struck him on the back of the head then, hit him like a hammerblow, and lightning pulsed in the darkness of his mind as he crumpled to the floor.

* * *

The Marquis de Carabas could not move his arms. They were, he realized, tied behind him. He was lying on his side.

He had been unconscious. If the peoplethe Marquis aloud, wondering how he could have missed knowing something so obvious, so basic. There was a tiny part of him, somewhere distant, that wondered what that actually meant.

They reached the place they were going, and it was good to be among friends.

Time passed strangely in that place, but soon enough the Marquis and his friend with the grey-green face and the long nose were given a job to do, a real job, and it was this: they disposed of those members of the flock who could no longer move or serve, once anything that might be of use had been removed and reused. They removed the last of what was left, hair and tallow fat and all, then they dragged it to the pit, and dropped


and recalled to court Ser Otto Hightower, the queen's father, who had filled the office before for both Viserys and the Old King.

Yet hardly had Ser Otto arrived at the Red Keep to take up the Handship than word reached court that Princess Rhaenyra had remarried, taking to husband her uncle, Daemon Targaryen. The princess was twenty-three, Prince Daemon thirty-nine.

King, court, and commons were all outraged by the news. Neither Daemon's wife nor Rhaenyra's husband had been dead even half a year; to wed again so soon was an insult to their memory, His Grace declared angrily. The marriage had been performed on Dragonstone, suddenly and secretly. Septon Eustace claims that Rhaenyra knew that her father would never approve of the match, so she wed in haste to200 Logstash patterns for filtering items such as words, numbers, and dates in AWS, Bacula, Bro, Linux-Syslog and more. If you cannot find the pattern you need, you can write your own custom pattern. There are also options for multiple match patterns, which simplifies the writing of expressions to capture log data.

Here is the basic syntax format for a Logstash grok filter:

%{SYNTAX:SEMANTIC}

The SYNTAX will designate the pattern in the text of each log. The SEMANTIC will be the identifying mark that you actually give that syntax in your parsed logs. In other words:

%{PATTERN:FieldName}

This will match the predefined pattern and map it to a specific identifying field.

For example, a pattern like 127.0.0.1 will match the Grok IP pattern, usually an IPv4 pattern.

Grok has separate IPv4 and IPv6 patterns, but


members of the Church approve women bishops. Strikingly, the house of bishops voted 44-3 in favor (with 2 abstentions.) According to the Guardian[2], the house of bishops will convene an emergency session to consider ways to rescue the measure.

Arguably, the proposal was flawed. In an attempt to foster passage, a compromise clause was added that would allow parishes who did not wish to be led by a woman bishop to be answerable to a male bishop instead. The Church has ordained women priests since 1994, but traditionalists have been able to basically ignore them, finding more congenial parishes in which to worship, and the "opt-out" provision would allow them to continue to avoid female leadership.The tradionalists' concerns include these:Consecrating (if that is the correct term in that church)List of best-selling albums of the 1980s (Japan)

The following list indicates the best-selling albums from 1980 to 1989 on the Japanese Oricon chart. It is based on cumulative sales figures of three formats (on vinyl, audio cassette, and compact discs).

Albums

References

Japan
Category:1980s in Japanese music


Differential characteristics, stroke recurrence, and predictors of covert atrial fibrillation of embolic strokes of undetermined source.
Background and purpose Identifying embolic strokes of undetermined source (ESUS) patients likely to harbor atrial fibrillation may have diagnostic and therapeutic implications. Our aim was to examine differences between ESUS and cardioembolic strokes, to evaluate stroke recurrence rate among ESUS and to identify baseline characteristics of ESUS patients who were later diagnosed with atrial fibrillation. Materials and methods We assessed all ischemic stroke patients admitted between June 2012 and November 2013. ESUS were compared to cardioembolic strokes at discharge. After at least 12-month follow-up, ESUS patients diagnosed with atrial fibrillation were compared to those who remained as ESUS. Results There were 236 ischemic strokes, 32.6% were ESUS. Compared to cardioembolic strokes, ESUS werethe circumstances and possible consequences," she said.

Website proprietor Ross MacKenzie told the Waikato Times that he had been authorised to confirm the transaction, but was committed to protecting the student's identity.

Comments

Berny - 2010-02-03 07:38

huh what i cant believe what i just read now its really a disgrace.For a young girl to sell herself to pay for school fees where is he parents or family members.this girl was brave to do this they could have kill her after taking her viginity what an article

GTG - 2010-02-03 07:58

you go girl, its better than giving to some guy who will forget about you afterwards. get your education!

I don't think it was the only option for her to raise money for the varsity fees. as ladies we must respect our bodies. all


privileges, what more can the human race expect from stupidity.

Jac7 - 2010-02-03 08:19

Dear lord,everything is a joke now-a-days. University is overrated girl, you could make it on your own. Well, guess she kinda is. Well, it would be an interesting story to tell the kids...

PRESHEN GOVENDER - 2010-02-03 08:23

Virginity is not an act of dignity it is a lack of opportunity

Paul - 2010-02-03 08:26

It's sad that she had to sell/sacrifice herself this way, but we all do things sometimes that we thought we wouldn't, especially when times are truly tough. Well done in your strength to see this through.

Bigfoot - 2010-02-03 08:26

Well done girl. I hope you are studying commerce and marketing because htis is a great way to make the money you need by selling soemthing rare.

Leonpermission.
//
// THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
// AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
// IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
// ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE
// LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
// CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
// SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
// INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
// CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
// ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
// POSSIBILITY OF SUCH DAMAGE.
//
// Author: keir@google.com (Keir Mierle)
//
// A convenience class for cost functions which


these early works, it was concluded that most of the genomic diversity is contained in the global virome and that most of this diversity remains uncharacterized. This view was supported by individual genomic sequencing project, particularly the mycobacterium phage.

Methods of study

In order to study the virome, virus-like particles are separated from cellular components, usually using a combination of filtration, density centrifugation, and enzymatic treatments to get rid of free nucleic acids. The nucleic acids are then sequenced and analyzed using metagenomic methods. Alternatively, there are recent computational methods that use directly metagenomic assembled sequences to discover viruses.

The Global Ocean Viromes (GOV) is a dataset consisting of deep sequencing from over 150 samples collected across the world's oceans in two survey periods by an international team.

Virus hosts

Viruses are themost abundant biological entities on Earth, but challenges in detecting, isolating, and classifying unknown viruses have prevented exhaustive surveys of the global virome.  Over 5 Tb of metagenomic sequence data were used from 3,042 geographically diverse samples to assess the global distribution, phylogenetic diversity, and host specificity of viruses.

In August 2016, over 125,000 partial DNA viral genomes, including the largest phage yet identified, increased the number of known viral genes by 16-fold.  A suite of computational methods was used to identify putative host virus connections.  The isolate viral host information was projected  onto a group, resulting in host assignments for 2.4% of viral groups.

Then the CRISPR–Cas prokaryotic immune system which holds a "library" of genome fragments from phages (proto-spacers) that have previously infected the


Interesting clues because the dude who played Thurston Howell III (Jim Backus) only appeared in Sabattini Death. Soooo.... That's not included in the correct episode choices Chibbi mentioned... I'm staying out of this one!!!The Cryptocurrency market and its flaws Do you regret not having invested in Bitcoin some 9 years ago? Nobody could have ever predicted the incredible growth of Bitcoin. Cryptocurrencies are not supported by Governments, yet the total market capitalisation of...


Level 4 autonomous vehicles for sale, though automakers and headlines continue to insinuate or outright declare they'll be here in three years' time, by 2020:

But although the cars are improving, none of the experts with whom we spoke believe Level 3 autonomy is safe—and that the issue has largely to do with people. A self-driving car operating in autonomous mode can create in drivers a false sense of security and a susceptibility to distraction, making an emergency disengagement more dangerous because the point at which the driver needs to retake control of the vehicle is also a point at which he is poorly equipped to do so. The specification says, in effect, "Your car will drive for you, but you need to watch it while it does, justlighting issue," he says, referring to the loss of image quality that occurs in situations like direct sunlight, poor or extreme contrast, or fog.

A vehicle's ability to "see" and translate its surroundings comes from onboard sensors. The three major sensor systems in use, alone or in combination, by vehicles currently on the road are: 1.) cameras; 2.) radar; and 3.) Light Detection and Ranging (LIDAR), currently a very expensive system that measures range via pulsed laser, and can be found atop Google’s latest self-driving minivan and Uber’smodified self-driving Volvo XC90s , among others. Google's 64-channel LIDAR system is good to 120 meters, creates a 360-degree image, has a 26.9-degree field-of-view, and can take more than two million readings per second.

An eager marketplace tends to trample or dismiss such


a plane's autopilot flies under the constant supervision of at least one pilot ready to intervene immediately, and at no time to do cockpit personnel watch movies or go to sleep on the flight deck. Knowing all of that, the name "Autopilot” makes sense (although it should also be noted that studies by NASA and others show that pilots also have a hard time paying attention to their autopilots ).

"Given the claim that consumers could confuse the autonomous driving capability of the F015 concept car with the driver assistance systems of our new E-Class in our ad 'The Future,' Mercedes-Benz USA has decided to take this ad out of the E-Class campaign rotation,” the company said. A version of “The Future” uploaded to the Mercedes-Benz USA YouTube channelhave suggested how the NHTSA might handle regulating an industry suddenly filled with new and niche players working beyond traditional vetting and recall procedures originally designed for major automotive manufacturers. Among his numerous publications, Walker Smith wrote a 100-page paper titled "Lawyers and Engineers Should Speak the Same Robot Language" that addressed this very issue. When asked about potential pitfalls in this early development phase, Smith said that "one of the questions we’ll really struggle with is how to deal with a less top-down industry, because "major automakers, suppliers, Silicon Valley companies that do this research will have strong reputational [and] financial interests to act deliberately." "There will be some smaller startups that may or may not have those same interests," Smith says. "And that could be concerning


media regulation since Theresa May became Prime Minister.

The FT looks back to Mr Murdoch's failed bid five years ago - when Mr Murdoch's Fox company was part of the News Corp group - and notes that the then-Culture Secretary Jeremy Hunt sought assurances of editorial independence from the bidder.

The newspaper says it's unclear whether the renewed attempt - with Fox now separated from News Corp's papers - will face similar scrutiny.

The Guardian quotes company insiders expressing confidence the deal will clear regulatory hurdles, because Fox has now separated from News Corp.

It also speculates that the European Commission is likely to take an interest, following Sky's acquisition of Sky-branded services in Germany, Austria and Italy in 2014.

'Secret showdown'

image copyright Getty Images image caption Sources told the Sun that the- warning of a "very worrying" rise in Turkish officers deployed to Nato who, the email says, have a "radical mindset" and "hate western organisations".

In its leader, the Times urges Nato to reapply for its job as Turkey's natural home, warning that the country's dependability as an ally is becoming open to question.

image copyright AP image caption The new 'fiver' is up for an award

The Bank of England's new plastic five pound note has had a difficult start to life. It's attracted the ire of vegans and has been banned from some Hindu temples, because it contains traces of beef fat.

But - as the i reports - that has not prevented it from being nominated for new banknote of the year, by the International Bank Note Society.

It will


The steady state intermediate of scallop smooth muscle myosin ATPase and effect of light chain phosphorylation. A molecular mechanism for catch contraction.
The ATP-induced difference UV-absorption spectrum of myosin isolated from the opaque portion of scallop smooth muscle (opaque myosin) was Ca2+-sensitive at 40 mM KCl and 1.5 M sucrose. On adding sucrose to 1.5 M, the turbidity of myosin decreased to 24% and the characteristic two forms of the difference spectrum, the ATP-form and ADP-form (Morita, F. (1967) J. Biol. Chem. 242, 4501-4506), were distinguishable. In the presence of Ca2+, the difference spectrum was the ATP-form first and then decayed into the ADP-form with the depletion of ATP. In the absence of Ca2+, however, only the ADP-form was observed. The ADP-form observed in the absence of Ca2+ returned  // root so the IDE can find the files.
    String from = "/proc/self/cwd";
    String to = workspaceRootDirectory.getPath();
    String subPathCommand = String.format("set substitute-path %s %s", from, to);

    return ImmutableList.of(subPathCommand);
  }

  private boolean useTestUi() {
    return BlazeCommandName.TEST.equals(handlerState.getCommandState().getCommand());
  }

  private final class GoogleTestConsoleBuilder extends CidrConsoleBuilder {
    @Nullable private final BlazeTestUiSession testUiSession;

    private GoogleTestConsoleBuilder(Project project, @Nullable BlazeTestUiSession testUiSession) {
      super(project, /* CidrToolEnvironment */ null, /* baseDir */ (File) null);
      this.testUiSession = testUiSession;
      addFilter(new BlazeCidrTestOutputFilter(project));
    }

    @Override
    protected ConsoleView createConsole() {


difficulty in food intake and sleep on 13^th^ day. 90% of the lesions healed within 20 days. Generalized itching reduced by 22^nd^ day of treatment. There was reduction in raised total WBC count, ESR and Eosinophils \[[Table 3](#T3){ref-type="table"}\]. Biochemical markers were within normal limits before discharge \[[Table 4](#T4){ref-type="table"}\]. On the day of discharge (30^th^ day), all skin lesions were healed and similar ongoing treatment was prescribed on the day of discharge. This showed good results \[[Figure 1](#F1){ref-type="fig"}\]. There was no fever and any medical or surgical emergency during hospital stay. *Pañcatikta Ghṛta* (20 ml with milk once in morning) was prescribed for 6 months and *Ārogyavardhinī rasa, Gandhaka rasāyana* and combination of *Guḍūcī, Khādira* and *Vasā* were continued for one year in the follow-up period. During follow upof the medicines used in this case \[[Table 5](#T5){ref-type="table"}\]. Among the medicines, *Khādira, Vasā, Pañcatikta ghṛta* and *Pañcavalkala Kvātha* may have caused anti inflammatory effect, while *Guḍūcī* and *Pañcatikta ghṛta* the immuno-modulatory effect. Wound healing properties of topical formulation helped in healing of wound created by blisters. Anti microbial, Anti fungal, analgesic and hepato-protective actions prevent associated symptoms of the disease.

######

Proven pharmacological actions of the prescribed formulations

![](ASL-36-229-g006)

Conclusion {#sec1-4}
==========

The presented combination and management by Ayurvedic medicament is found to be a good alternative therapy in autoimmune bullous disorder. Long-term prospective studies are required to substantiate the data.

Declaration of patient consent {#sec2-1}
------------------------------

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his images and other clinical information


Fibonacci Numbers

What are Fibonacci Numbers?

Fibonacci Numbers are the numbers found in an integer sequence referred to as the Fibonacci sequence. The sequence is a series of numbers characterized by the fact that every number is the sum of the two numbers preceding it. The initial two numbers in the sequence are either 1 and 1, or 0 and 1, and each successive number is a sum of the previous two as shown below:

Fibonacci numbers are named after Italian mathematician Leonardo Fibonacci, also known as Leonardo Pisano. In his 1202 book, Liber Abaci, Fibonacci introduced the sequence to European mathematicians, even though the sequence was already known to Indian mathematicians. Since Fibonacci’s father was a merchant, he traveled widely, allowing him to learn the Hindu-Arabic arithmetic system while growingTuesday, March 30, 2010

After Sunday's accidental overdistance, I was going to be running much less- just six miles after work. I tried running with the Lululemon running club in Logan Circle. It was alright- we had to deal with traffic lights heading down to the Mall, so that was a pain. There were also two fellows who insisted on racing each other every block, but stopping at the intersections regardless of whether they had the right of way from the light, on the way back. I surged once and got ahead of them with ease and I think that cooled them down a little bit. My legs were a little sore, expecially my right upper quad, so hopefully the easy six was light enough to get them ready


on the property are believed to have been brought from Japan by Commodore Matthew Perry as a result of his historic visit in 1854. General William H.R. "Rooney" Lee, son of Gen. Robert E. Lee, was captured by Union soldiers on the property but his younger brother escaped capture by hiding in the plantation's famous box hedges. The property is the largest still in the hands of one family in Virginia. The main house of this plantation includes an 1857 wing and an 1875 front section built to replace an 1827 section that burned.I left the Herald-Progress in July 2005, to work at the Richmond Times-Dispatch. I feel like I gave up a little bit, because I knew nobody would put in the kind of work I oncebe scooped up by the sweeping car. I made it.For 26 minutes as I ran along Old Ridge Road, I saw nobody- no walkers, no dogs, no cars. It was eerie, but great, because I could run down the middle of the roads.Afterward I grabbed a copy of the current Herald-Progress. I was unimpressed.

Saturday, March 27, 2010

I didn't run a great race- I was shooting for 5:20 or below for my pacing and averaged 5:23 to finish in 33:27, running a full minute slower than my 10k PR. I did, however, relish being in Richmond. I have a pronounced tenderness in my heart for Pittsburgh. I like living around Washington. I love Richmond.

The train ride was about three hours, twice as long as it should have been, and


I was suffering with serious congestion and a miserable sore throat. The only enjoyable part was a few minutes when I fell asleep sitting up, listening to my Genghis Kahn biography on my mp3 player. I got in Friday afternoon and my Spider teammate Emily Ward picked me up at the train station. I smiled widely when I looked around downtown Richmond. What a place!

I decompressed in her guest room and we joined her neighbors and friends for dinner at Joe's Inn, where I promptly ate too much chicken parm, but it was delicious. We sat in the bar, which inexplicably still allowed smoking, so I had to take a few breaks outdoors to get fresh air. We watched some of Risky Business and I went to bedhands on my knees, trying to stop the ground from moving. I was too far out to make going back any easier, so I trudged on. Eventually I hit a mile-long downhill that lifted my spirits, but in the end I mustered maybe three miles of tempo effort.

Sunday's long run marked several points- my adjustment to the hills, a stunning recovery from eating a lot of steak and drinking a lot of bourbon at Matt's party the night before, and the welcomed improvement in sleep when I eskewed the mouthpiece. I met up with Shafer, Jo, Brandon G,Greg Brynes and Steve Garand to have them test out the 18-mile permutation of my Wild Wild West End loop, which I am constantly refining. Jo was only planning for 17


very least I could run 28:20.

Realistic- since I ran those miles alone, in the dark and in trainers, I should at least run 5:30s for 27:30.

Optimistic- I felt my reasonable limit was 5:15 pace for 26:15. Perhaps 5:20s for 26:30 would have been good.

I wound up 18th in 27:23, and I needed a strong kick to make that happen.

It was pouring in Falls Church, but only drizzling lightly in DC.

I held back at the start, wary of getting out with the Africans and Dirk. I still pushed at the beginning, and I can tell I was pushing too hard. 5:25 would have been a great first split, but I hit 5:18. Despite how fast it was,I felt good. The course, though pretty flat, was questionably designed, with fourperson exerts too much influence in the competition division, but I digress.

The rank-and-file members of the club are quick to volunteer to help hold a race, Janice Boyko does a great job organizing and Dave Sobal puts together safe and high quality courses.

Sadly, I was only able to make it to one of the three races in the summer cross country series because of conflicting road races. Each meet offered three different races:

2k- out and back on the Tranquil Trail4k- out on the Traquil Trail, along the lawn bowling courts on Reynolds, right on the Horseshoe Trail, right on the Kensington Trail, left on the Homewood Trail and back on the Tranquil Trail.

8k- The 4k course, then up the Falls Ravine Trail, around the exercise circuit twice and


I had been wearing to my old adiZeros, the shoes that had run 14:57 their first time out of the box. They instantly felt a lot better and I was glad I switched back. We started out slowly on the first one, 78, but recovered with a 7 and two 76s for 6:27. Not bad. Then we got a little out of hand the next one, splitting 5:05 for the mile and 6:21 for 2k, but I still felt strong and able to keep doing it.The third one went smoothly in 6:26, and the fourth one was the same, but the middle was filled with a struggle over self doubt and insecurity.Was I actually in shape to finish this workout? There were some stretches where my breathing seemedseconds from the last, I kept in mind that I could just barely feel my legs, so to be able to run close on muscle memory was pretty good. I slowed a bit the next three laps and averaged 5:43 for 22:52. By the end, the t-shirt I was wearing over a long-sleeved shirt was soaked and pretty heavy.Overall, I was pretty happy with the workout. Considering I ran 5:40 pace for 2x3 miles on the track two weeks ago, running 2x4 miles on the roads averaging that pace is pretty good. That I only looked at my watch at the mile marks made me pretty confident that 5:40 just became a natural pace. Now, to speed it up...

Monday, March 1, 2010

My morning run plan failed again, so


Once you've gone through a list of careers such as the one in your book or in the Occ. Outlook handbook, what do you recommend for narrowing down the list? Like you said, there could be many careers that seem interesting...I agree with your overall approach, btw...seems much more effective in theory at least than taking career tests/skill inventories and such.

Google the name of the career and the word "careers"--for example, "geologist careers." That should generate articles on the subject. If it still appeals, insert that same search term in Amazon to find a book on the subject. The best books consist of separate chapters written by different people in the career. Next step is one or more informational interviews and/or job shadows. Do that and chances areThe Civil Rights Act Passes the HOUSE OF REPRESENTATIVES

My history – and a civil rights timeline. I was a senior at Ponderosa High School in Shingle Springs, CA, when the HOUSE OF REPRESENTATIVES passed a final version of the Civil Rights Act on February 10, 1964… The Civil Rights Act of 1964 prohibits discrimination on the basis of race, color, religion, sex or national origin. Passage of the Act ended the application of “Jim Crow” laws, which had been upheld by the Supreme Court in the 1896 case Plessy v. Ferguson, in which the Court held that racial segregation purported to be “separate but equal” was constitutional.”


fell 8 percent in the same period, according to SEC filings. Of course, as my colleague Josh Harkinson has reported, some of America’s most successful CEOs have always gotten rich by squeezing workers. But defense contractors rarely get the same scrutiny as bank, insurance, and retail executives.

Could a lengthy strike further delay the F-35? Maybe; Lockheed reports no effects on its assembly line so far, though it has notified the military services that there could be problems delivering the jets on time. But with conservatives on a renewed hunt for communists and the House Armed Services Committee meeting this week to discuss the annual defense budget, expect Republicans to defend their No. 1 private contractor while tossing a couple of barbs at those “unpatriotic” union workers down inor equal to 1?
True
Suppose -6*c + 26 = -10. Let b be 30/(-48)*4*c/5. Is b at most -2?
True
Let u(x) = 3*x**2 - 30*x - 13. Let h be u(14). Which is bigger: 154 or h?
h
Let x(f) = f - 3. Let r be x(4). Let j be -228*4/(-680) + -2. Let c = j + 3/5. Is c at least as big as r?
False
Let t(p) = -p**2 - 7*p. Let a be t(-6). Let m be (-2)/(-7) + (-33)/(-7). Are m and a unequal?
True
Let u = 38 + -37. Let o = 341 - 235. Is o smaller than u?
False
Suppose 15 = 5*l - 0*l. Let a(p) = -p**2 + 4*p - 1. Let o be a(l). Suppose -o*g + 3*g = -2. Is -2 at most as


remedy at law against the state, which is not true where a city is involved. The distinction between the two situations is recognized in the Richfield case.
2. Where the city abandons the condemnation of land included in a condemnation proceeding, is the landowner entitled to recover expenses, including attorney's fees, incurred in protecting his rights in the condemnation proceeding?
*36 Minneapolis City Charter and Ordinances (Perm. ed.) c. 10, § 6, provides in part:
"* * * Said Court [on appeal] shall allow a reasonable compensation to such Commissioners for their services, and make such award of costs on such appeal, including compensation of such Commissioners as it shall deem just in the premises.
"In case the Court shall be of the opinion that such appeal was frivolous or vexatious, it
# batch

  Simple async batch with concurrency control and progress reporting.

## Installation

```
$ npm install batch
```

## API

```js
var Batch = require('batch')
  , batch = new Batch;

batch.concurrency(4);

ids.forEach(function(id){
  batch.push(function(done){
    User.get(id, done);
  });
});

batch.on('progress', function(e){

});

batch.end(function(err, users){

});
```

### Progress events

  Contain the "job" index, response value, duration information, and completion data.

```js
{ index: 1,
  value: 'bar',
  pending: 2,
  total: 3,
  complete: 2,
  percent: 66,
  start: Thu Oct 04 2012 12:25:53 GMT-0700 (PDT),
  end: Thu Oct 04 2012 12:25:53 GMT-0700 (PDT),
  duration: 0 }
```

## License

(The MIT License)

Copyright (c) 2013 TJ Holowaychuk <tj@vision-media.ca>

Permission is hereby granted, free of charge, to any person obtaining
a copy of this software and associated documentation files (the
'Software'), to deal in the Software without restriction, including
without limitation the rights


Retrograde left ventricular catheterization in patients with an aortic valve prosthesis.
Twenty-seven consecutive patients with an aortic valve prosthesis were evaluated with retrograde left ventricular catheterization. The prosthesis was successfully crossed, permitting hemodynamic and angiographic evaluation of function of the prosthetic valve, left ventricle and mitral valve in all 27 cases. No complications were encountered. In patients with active endocarditis or recent embolization, the retrograde technique was avoided when possible, and attempts were made to utilize other techniques for study. However, three such patients were evaluated with the retrograde technique without complication. Examination of pressure tracings and cineangiographic films suggested only minor interference with valve poppet movement induced by the catheter transversing the valve. In three cases, hemodynamic data were recorded with the catheter crossing the prosthesis at oneester is cleared by the liver, and the remainder is cleared by peripheral tissues.\[[@pone.0205747.ref008]\] Once in the blood, retinol forms a complex with retinol binding protein 4 (RBP4), and inside the cell it is metabolized and converted to retinoic acid by various enzymes via a two-step oxidation process ([Fig 1](#pone.0205747.g001){ref-type="fig"}).\[[@pone.0205747.ref008]\] All-*trans* retinoic acid is the main endogenous active retinoic acid metabolite. It regulates specific nuclear receptors (retinoic acid receptors, RAR, and retinoid X receptors, RXR) which in turn influence the expression of several genes that play a role in cell growth, differentiation, development, and homeostasis.\[[@pone.0205747.ref009],[@pone.0205747.ref010]\]

![Intracellular metabolism of retinol (vitamin A) in the liver.\
Retinol is provided by our diet and transported via chylomicrons into the liver, where it is bound to retinol binding protein (RBP). Retinol is converted to


        15   54.5 ± 5.0[^A^](#t001fn003){ref-type="table-fn"}^,^[^B^](#t001fn003){ref-type="table-fn"}

  **ALT (U/L)**                                              22   19.5 ± 11.4               17   51.1 ± 18.5 [^A^](#t001fn003){ref-type="table-fn"}   15   85.1 ± 40.2[^A^](#t001fn003){ref-type="table-fn"}^,^[^B^](#t001fn003){ref-type="table-fn"}

  **ALP (U/L)**                            differentiation, and consequently carcinogenesis and patients with NASH have increased risk for HCC. Until this report, no studies have assessed the expression of genes related to retinoid-metabolism and their association with plasma retinol in NAFLD patients.

Upregulation of *AKR1B10* in NAFLD could be due to the presence of oxidative stress,\[[@pone.0205747.ref037],[@pone.0205747.ref038]\] particularly in NASH. \[[@pone.0205747.ref039]\] Aldehydes such as 4-hydroxynon-2-enal, 4-oxonon-2-enal, malondialdehyde and others oxidative stress-related compounds may induce *AKR1B10* as part of the cellular defense response against oxidative stress. \[[@pone.0205747.ref013],[@pone.0205747.ref018],[@pone.0205747.ref037]\] A pro-oxidant state is well documented in NAFLD patients compared to control subjects as evidenced by e.g., a higher content of protein carbonyls, GSH depletion, low catalase activity, an increment of both 3-nitrotyrosine immunoreactivity and production of O2•− and malondialdehyde by Kupffer cells.\[[@pone.0205747.ref039]\] However, in a previous study, done by


2-week period; the training program was based on endpoints of the EBC-Psy intervention. The psychological measurement was administered by an experienced psychologist. Both psychologists were blinded as to the aim of the study. The scoring of the testing protocol was conducted by external blind judges. All EBC-Psy intervention sessions were recorded by digital camera; seven random sessions were used for internal quality control review and clinical supervision by a clinical team.

Medical staff members were involved in the enrolment of the sample and were in charge of managing the clinical path and check-up.

Psychological Testing
---------------------

The psychological measurement was conducted by self-reported testing to evaluate four emotional variables: anxiety, angry, psychological distress, and depression.

The following psychological tests were used: the State-Trait Anger Expression Inventory (STAXI) to measure the anger state, theThe EBC-Psy is a brief treatment based on emerging scientific findings about a new pattern of psychological needs from a population involved in intensive medical settings. Preliminary data demonstrated encouraging outcomes in this vulnerable population, highlighting the positive impact of the EBC-Psy. However, the study is still ongoing with a larger number of participants to finalize the results. At the same time, the participants who adhered to the clinical protocols have reduced their distress and depression in their daily activities. The keys of the EBC-Psy intervention on emerging psychological needs for new BC targets (younger patients) are the screening of psychological distress, well-timed intervention after diagnosis, and the shaping of coping strategies. The main goals of the intervention were to reduce distress and enhance treatment benefits. The positive


The invention relates to a novel process for preparing N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides, which are known as intermediates in the preparation of herbicides, to novel N-(2-cyano-4,5-difluoro-phenyl)-sulphonamides and N-(2-cyano-4,5-difluoro-phenyl)-sulphonimides as intermediates for this process and to processes for their preparation.
It is known that certain N-(5-amino-2-cyano-4-fluoro-phenyl)-alkanesulphonamides, such as, for example, N-(5-amino-2-cyano-4-fluoro-phenyl)-methanesulphonamide, are obtained when corresponding halogenated benzene derivatives, such as, for example, 1-amino-4-cyano-2,5-difluoro-benzene, are heated with alkanesulphonamides, such as, for example, methanesulphonamide, in the presence of an acid binder, such as, for example, potassium carbonate, and in the presence of a diluent, such as, for example, N-methyl-pyrrolidone (see EP-A-648772). However, this process affords the desired products in unsatisfactory yields. Accordingly, there is a need for a more favourable preparation process for N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides.
It has now been found that N-(5-amino-2-cyano-4-fluoro-phenyl)-sulphonamides of the general formula (I)of the general formula (I) can be obtained by the process according to the invention in a relatively simple manner in high yields and in very good quality, and a pure end product can be prepared via a mixture of intermediates. The intermediates of the formulae (IV) and (V) can be obtained as mixtures in virtually quantitative yield. The main advantage of the process according to the invention is the fact that the use of relatively expensive 2,4,5-trifluoro-benzonitrile can be dispensed with, and the problematic exchange of a fluorine substituent for a sulphonylamino group is not necessary.
The compound 2-amino-4,5-difluoro-benzonitrile of the formula (II) to be used as starting material has not yet been disclosed in the literature; as a novel substance, it also forms part of the subject-matter


(the HI level).
In the period d, the branch target instruction MOV D2, A0 is fetched in the IFB 2 in accordance with the BRTKN 9. Although the AND D0, D1, which has been fetched based on the prediction that the branch would not be taken, is decoded in the DECB 3, the BEQ disp8 is executed in the EXB 4. That is, the decoding of the MOV D2, A0 in the DECB 3 is cancelled in accordance with the BRTKN 9.
In the period e, the branch target instruction MOV D2, A0 is decoded in the DECB 3 and no operation is performed in the EXB 4 because the decoding of the AND D0, D1 has been canceled.
In the period f, the branch target instruction MOV D2, A0 isbut in this case it’s a simple Dramatic Reveal (spoiler alert): Katherine (who, to be fair, admitted up-front that “Katherine Plumber” was a nom de plume) is actually the daughter of Joseph Pulitzer, the newspaper magnate against whom Jack is striking. There is a temporary rift between them, but Katherine follows Jack to his rooftop refuge and tells him her true feelings:

After that, they are united against the greater enemy until the end, at which point it becomes clear that they’re going to be Together Forever. Like I said, pretty standard as such things go. Still, I couldn’t help but think as I watched: they’re from vastly different social classes and backgrounds. She’s well-educated, while he spent his youth trying not to starve. He’s working for her father


of any love affair. Still, I couldn’t help but think, as I was watching them up on Jack’s rooftop:

I wanted to say to them: “Katherine? Honey? Just hike up that skirt and bend over that railing. You know that’s what you both really want.”

Some would respond that people – especially girls of Katherine’s social class – didn’t do that back then. Of course, they did. People, even girls of Katherine’s social class, have always done that. For about the first 190,000 years of the 200,000-year existence of our species, “Hey, you’re cute/I like you, do you want to have sex?” was a pretty uncontroversial thing to say. It was only when we figured out where babies come from that people started caring who had sex with who.

The differencetested and recommended by the studios responsible for those blockbuster games, so you can be sure you’ll be getting the best from the best. What’s more, there will be other Elite Mappings coming for other blockbuster titles such as Call of Duty: Black Ops III and Star Wars Battlefront.

The Xbox Elite Wireless controller gives you so many ways to customize your controller right out of the box with the included thumbsticks (6), paddles, (4) and D-pads (2). But if you want to add even more to your new controller this holiday, you are in luck. Last week we announced an exclusive partnership with Scuf Gaming to create add-ons for the Elite Controller. While we work with Scuf Gaming to develop those designs, we are pleased to announce a


that one! ! In the Renaissance faith and acquisition were get downing to be thought of as separate and Machiavelli was a adult male of his clip. His book was wholly didactic and did non hold a hint of faith. He spoke of inhuman treatment and fraudulence in prosaic tones and maintain his book purely a manual. with no opinions. In our modern clip. we have to spot his book in the same mode that he wrote it. If we do non. we will non understand what he was composing.же нужной энергией обладают $10^{-12}$ молекул (если $e^{-\lambda}=10^{-12}$, то $\lambda\sim 30$ то реакция проходит за время порядка 1000 секунд. В этом случае легко показать, что пр и увеличении средней энергии на $0.3\%$ количество частиц с нужной энергией возрастет весьма значительно, примерно на $10\%$.

[**5.**]{} По ходу дела могут обсуждаться случайные блуждания, оцениваться длина пробега в зависимости от диффузии и т.д. В зависимости от времени и силы школьников.

[199]{}

, [*Проблемы одаренности и стадийность математического обучения*]{}, Математическое образование, 3:1, Январь-Март (2010), 2–5, Engl. transl. [*A.Kanel-Belov, R. Yavich*]{} (2012) [*Staging of Mathematical Education*]{},// Athens Institute for Education and Research// ATINER’s Conference Paper Series MAT2012-0176// Athens, Greece, June 2012, pp 5–9 // ISSN 2241–2891, http://www.atiner.gr/papers/MAT2012-0176.pd

(Рук. Белов А. Я.) [*Распределение Максвелла.*]{} Поиск – 93, материалы конференции, физика, математика, астрономия, экология, 1993, Москва, ДНТТМ, стр. 23–29

Математика в


школе. – N1, 1996, стр. 14–20.

Некоторые актуальные проблемы современной математики и математического образования. – СПб.: БАН, 2005, с.152–-158.

РГПУ им. Герцена, некоторые актуальные проблемы современной математики и матем. образования, Матер. научн. конф. Герценовск. чтения, $LIX$ 16–21 апреля 2007, СПБ 2007, стр. 239–245

РГПУ им. Герцена, некоторые актуальные проблемы современной математики и матем. образования, Матер. научн. конф. Герценовск. чтения,$LX$ 17–22 апреля 2007, СПБ 2006, стр. 168–172

РГПУ им. Герцена, некоторые актуальные проблемы современной математики и матем. образования, Матер. научн. конф. Герценовск. чтения, $LXII$ 13–18 апреля 2009, СПБ 2009, стр. 196–199
pRefcount = this->mRefcount;
			pointer ptr = mPtr;

			//to avoid unexpected dead recursion, first clear the data
			this->mRefcount = NULL;
			this->mPtr = NULL;

			BLADE_DELETE pRefcount;
			BLADE_DELETE ptr;
		}

		pointer		mPtr;
		RefCount*	mRefcount;
	private:
		mutable Lock		mLock;
	public:
		static const Handle	EMPTY;
	};

	template <typename T>
	const Handle<T> Handle<T>::EMPTY;

	class BLADE_BASE_API ALock : public Lock, public Allocatable {};
	typedef Handle<ALock> SHARED_LOCK;

}//namespace Blade

#endif // __Blade_Handle_h__


brightly as the object and the formula $\exp(i\,k\,R)/(1+ (i R/R_0))$ means that, in the farfield, each scatterer contributes a power proportional to $1/R^2$ to the pixel. So far so good: it seems the sensitivity of the instrument to out-of-focus information drops off very swiftly with distance from focus. Not swiftly enough, for we must sum up the noise contribution from the whole out of focus volume. If we assume scatterers (noise objects) are roughly equally responsive and are uniformly distributed in the large, then we can do this summation in spherical shells as shown. So each scatterer in the spherical shell a distance $R$ from the focus contributes noise power proportional to $1/R^2$ but each spherical shell volume varies like $R^2$ so that roughly each spherical shell ofQ:

Uncaught SyntaxError: Unexpected token e

I am getting Uncaught Syntax Error newly, the only addition is sending/retrieve json data from server to client. How to investigate what it is? Below is the screen shot
Sometimes i get the following error in google chrome.

Below have the details which i lately updated to my code before we get this error.
Java Script
// Post the topic in the post section
     function  updatePost(xhr, status,jsonData){
                    var args = $.parseJSON(jsonData);

Data printed from the server log before sending to client
10:20:15,101 INFO  [stdout] (http--127.0.0.1-8080-14)  Printing json data  {

10:20:15,102 INFO  [stdout] (http--127.0.0.1-8080-14)   "topic_username" : "srikanth marni",

10:20:15,102 INFO


my blog if I left out the sheep.

Not a good photo really but I was standing on a bridge and they were underneath ,just thought their colouring was a little different.

I took a photo of the inscriptions of the history of Corfe but won't bore you with the whole thing just to show you a taster if you like.

Pesky sheep get in all the pics , While we were in Corfe we just had to pop in to the Old fashioned sweet shop, be warned the jars were not about to tumble off the shelf, blame the photographer ,(I do not do straight\).

I think everything has a list to the left lol. We also wanted to visit here but alas it was closed.

Enid Blyton spent a lot of       public void onClick(View v) {

                final String user_name = setupName.getText().toString();
                Log.d("LogInformation", user_name);
                if (!TextUtils.isEmpty(user_name) && mainImageURI != null) {

                    setupProgress.setVisibility(View.VISIBLE);
                    if (isChanged) {


   }

        Map<String, String> userMap = new HashMap<>();
        userMap.put("name", user_name);
        userMap.put("image", download_uri.toString());

        firebaseFirestore.collection("Users").document(user_id).set(userMap).addOnCompleteListener(new OnCompleteListener<Void>() {
            @Override
            public void onComplete(@NonNull Task<Void> task) {

                if(task.isSuccessful()){

                    Toast.makeText(SetupActivity.this, "The user Settings are updated.", Toast.LENGTH_LONG).show();
            “A more likely outcome, HMG (Her Majesty’s Government) assesses, is a situation similar to medieval Italy, where different actors control and secure small pockets around the country,” the cables report.

Another cable, recording an experts meeting in Berlin in November 2009, acknowledged that “the participants expressed frustration with the TFG”. Sweden, in particular, commented that the ministers “were not performing and the TFG has no strategy whatsoever”.

The TFG was also criticised by neighbouring Djibouti and Uganda. In a meeting between the US Deputy Assistant Secretary and the Djibouti Foreign Minister in December 2009, the latter is reported to have said that the government is weak and that Djibouti is privatively pressuring the TFG to be more proactive and deliver basic services in order to gain more credibility amongst the


population. Similarly, the Uganda representative affirmed that the TFG should be more concerned with obtaining the support of its population than the international community: “The TFG should focus on fostering patriotism not seeking helicopters.”

In a cable detailing a January 2010 meeting between Condoleeza Rice and the former UN Special Representative for Somalia (2007-2010) Ahmedou Ould-Abdallah , the latter questioned the government’s efficiency after it failed to ratify a constitution after more than 5 years. The constitution draft was finally completed on June 10, 2010. However, this is considered only a draft to “stimulate public debate”, and not the final version which the population could vote on.

It is perhaps not surprising that international governments have been reluctant to be outwardly critical of the weak and troubled TFG, but the2068 (4.4%) were with vancomycin. Those 2068 patients were matched to 8069 patients in the metronidazole group for a total of 10 137 included patients. Subcohorts were constructed that comprised 5452 patients with mild to moderate disease and 3130 patients with severe disease. There were no differences in the risk of recurrence between patients treated with vancomycin vs those treated with metronidazole in any of the disease severity cohorts. Among patients in the any severity cohort, those who were treated with vancomycin were less likely to die (adjusted relative risk, 0.86; 95% CI, 0.74 to 0.98; adjusted risk difference, -0.02; 95% CI, -0.03 to -0.01). No significant difference was found in the risk of mortality between treatment groups among patients with mild to moderate CDI, but vancomycin significantly


for memberships signed by the respondent's employees is immaterial. We conclude that under the circumstances the refusal of the Trial Examiner to grant the subpoenas requested did not prejudice the respondent.
The next three points raised by the Ferry Company have one fundamental question in common, namely, the propriety of the designation of the bargaining unit by the Board for the purposes of collective bargaining. The respondent takes the position that the determination by the Board of the bargaining unit was contrary to the *135 provisions of Sections 9(b) and (c), 29 U. S.C.A. § 159(b) and (c), and to those of the Board's own regulations (Sections 1, 3 and 10 of Article III, Rules and Regulations, Series 2 as amended.) To sum up this contention of the respondentthe respondent only two, so far as the record shows, objected to being represented by Local No. 333 and none objected because of the inclusion of licensed and unlicensed personnel in the same unit.
[4]  In re Panama R. R. Co., 2 N.L.R.B. 290, 294-295 (1936); In re Black Diamond S. S. Corp., 2 N.L.R.B. 241, 244-245 (1936); In re International Mercantile Marine Co., 1 N.L.R.B. 384, 388-390 (1936); In re Delaware-New Jersey Ferry Co., 1 N.L.R.B. 85, 93-94 (1935). The same principle has been constantly applied, without comment, in the following cases: In re Petroleum Navigation Co., 10 N.L.R.B. 1348, 3151 (1939); In re Cities Service Oil Co., 10 N.L.R.B. 954, 956-957 (1939); In re Tide Water Associated Oil Co., 9 N.L. R.B. 823, 827-828 (1938); In


for delay percentiles. In \[[@B18-sensors-18-03966]\], capacity development for packet-based radio access technologies through multiplexing gain is investigated. The authors conclude that multiplexing gain is achievable for traffic with variable bit rate but not for traffic with constant bit rate. A Software Defined Network (SDN)-based approach to packet aggregation and then disaggregation after transmission is presented in \[[@B19-sensors-18-03966]\].

The Asynchronous Transfer Mode (ATM) Adaptation Layer 2 (AAL2) represents a technique for multiplexing of packets in networks such as 3G. In this technique, several small packets are fitted into large ATM cells. In \[[@B20-sensors-18-03966]\], the authors present a probabilistic model of AAL2 for the 3G core network. In \[[@B21-sensors-18-03966]\], a queuing model for the evaluation of AAL2 packet multiplexer performance modelled as batch Markovian arrivals having timer mechanism is presented. Extensionadditional packets would result in improvement of multiplexing gain. Once the packet waiting duration reaches the timer expiration threshold $T_{max}$, the course of packet multiplexing is triggered. The large multiplexed packet is then transmitted to the BS. $N_{max}$ is the maximum number of resource blocks available for RN to use in a single Transmission Time Interval (TTI). If some or all of the $N_{max}$ radio resource block are not needed in a TTI for RN traffic, the unallocated blocks are made available for regular mobile users waiting for radio resources from the BS. Alternately, if the timer expiry time $T_{max}$ has not been reached, but the total size of small packets arrived at the multiplexing buffer reaches the size of $n_{max} - overhead$; the large multiplexed packet is


of $x^{th}$ packet is Erlangian \[[@B24-sensors-18-03966]\]. Therefore, the probability of subsequent arrival of packet prior to multiplexing with $x$ packets already in the buffer is denoted as $a_{x}$ and given as:$$a_{x} = \left\{ \begin{array}{lr}
{1,} & {x = 0} \\
{1 - \left( {\sum\limits_{i = 0}^{x - 1}\frac{e^{- \lambda T_{max}}\left( {\lambda T_{max}} \right)^{i}}{i!}} \right),} & {1 \leq x < r} \\
{0,} & {x \geq r} \\
\end{array} \right.$$

The probability of initiating the multiplexing after $x$ arrivals is $b_{x}$ where $b_{x} = 1 - a_{x}$. This multiplexer now emulates an r-stage Coxian process ([Figure 4](#sensors-18-03966-f004){ref-type="fig"}). The probability of an arrival with empty buffer, $a_{0}$ is 1 as the packet multiplexing starting without a single packet in the buffer is not possible. For triggering the multiplexing process, a single packet must arrive at= \sum\limits_{x = 1}^{r}N_{x,M} \times P\left\lbrack {X = x} \right\rbrack$$

The mean number of resource blocks consumed by a single multiplexed large packet, $k$ is dissimilar from the parameter, mean number of blocks utilized per TTI. The mean number of resource blocks per TTI are considerably decreased by employing the multiplexing scheme along with the timer. However, $k$ increases with usage of packet multiplexing scheme. The greater the value of $k$, the better the resource utilization. The multiplexing of packets happens if a duration $T_{max}$ has elapsed. If the packet aggregation scheme is not used at the RN and packets are sent to BS without multiplexing, then the arriving packets would be sent to BS immediately at the beginning of the next TTI, instead of waiting for the timer


(cells) are generated using models in \[[@B34-sensors-18-03966]\] and traces of these maps are fed into our OPNET simulation model. Noise and noise figure are modelled as per 3GPP specifications. Interference is modelled with in such a way that signals arriving from neighboring cells after reduction of power due to path loss, slow fading, and fast fading cause interference.

The RN OPNET model for relaying node is implemented to feature two radio interfaces, the Uu and the Un interfaces ([Figure 6](#sensors-18-03966-f006){ref-type="fig"}). The corresponding protocol stacks are implemented as per 3GPP end-user protocols. The relaying scheduler is implemented in the MAC layer of RN Uu interface. The proposed packet aggregation and multiplexing scheme is implemented at the Packet Data Convergence Protocol (PDCP) layer of RN Uu interface. The GPRS (General PacketThe report had hidden dots embedded in it. Soon after the report was published, the Department of Justice (DOJ) said that the Federal Bureau of Investigation (FBI) had detained an alleged leaker. Reality Leigh Winner, the 25-year-old NSA contractor, was accused “with removing classified material from a government facility and mailing it to a news outlet.”

The DOJ published an affirmation document in which an FBI agent briefed on how Winner had been traced. The agent said that the scanned copy of the report, provided by The Intercept to the government to ensure its legitimacy, seemed to be folded and creased, hinting that they had been printed and then hand-carried from a secured space.

Soon there was a buzz among researchers who claimed that the tracking dots embedded in the


his or her tracks more carefully, or where the leaked documents had been reproduced by more than six people or perhaps printed on a non-government printer, the dots certainly could be a significant player.

The history of the embedded codes can be traced back to more than 30 years, yet the technology has been kept hidden for so long.

Peter Crean, a senior research fellow at Xerox in 2004, provided the information for the article in PCWorld at that time. Crean, in his first public interview about the practice to Quartz, since talking to the magazine 13 years ago, revealed that Xerox had not done enough to share information about the dot’s presence.

Crean added that the buyers were not informed about it even if they asked. Similarly, the salespersons wereProgress was measured weekly via clinically validated outcome measures delivered online and personal communication with the patient in text messages within the platform.

Implementation process {#Sec7}
----------------------

An implementation strategy was developed to prepare the clinics and support the implementation process. The strategy comprised activities such as meetings, technical administration, training and technical support. At each pilot clinic, two to three therapists and the unit manager were involved. Generally, they participated in two preparatory meetings. The meetings aimed to describe ICBT in general and ICBT-i in particular, and to prepare processes such as customising the care routines and incident reporting to each clinic. There were also technical and administrative preparations, such as connecting the clinics to the online platform and distributing access levels. The ICBT-i programme and implementation plan were presented


for the whole staff at each clinic, to facilitate their involvement in recruiting patients. Therapists were provided with one full day of training on the programme, the technical platform and ICBT skills. Managers were trained in the technical administration. The implementation activities took place during a period of 2--6 months at each clinic, after which the therapists started their first treatments. Therapists were supervised and supported in clinical and technical issues by an experienced ICBT therapist, initially every second week, and later once per month.

The implementation process was led by a project group consisting of three psychologists, all with prior experience from ICBT. One of them, the first author, had the role of project manager.

Data collection {#Sec8}
---------------

Semi-structured interviews were conducted to gather information about the experiences during implementation ofICBT. Another experienced benefit of the technology was the continuous updates about patient progress and setbacks. This feature helped both the therapist and the patient focus on the agreed issues in their communications and overall treatment. Taken together, these aspects contributed to clarity and treatment structure, which facilitated implementation through favourable experience of the ICBT-i programme. The automatic notifications generated when patients scored high on the weekly question about suicidal thoughts were described as time-consuming rather than helpful, as they often required further suicide risk assessment that was not perceived as necessary.

The value proposition {#Sec16}
---------------------

### Desirability {#Sec17}

Most participants experienced the time and cost effectiveness of using ICBT-i as a great advantage. Compared to face-to-face therapy, one therapist can treat more patients in less time, providing a clear demand-side


wider system.

Embedding and adaptation over time {#Sec33}
----------------------------------

### Challenge to scale up {#Sec34}

Some concern was raised about the long-term implications of implementing ICBT-i in psychiatric health care, such as concern that ICBT-i would replace other treatments.

"*"If you have been in public health care for a while, you know that money plays a big part. You introduce something as an alternative, and say that this is not going to replace anything. Then you implement it and two years later you remove what you had before." (manager)*"

Participants believed that successful, sustained implementation of ICBT-i in psychiatric health care could be a challenge. Managers pointed out scepticism and lack of knowledge and interest among staff as important barriers to a scale-up. A successful result of this pilot implementation was seen as crucial,the interviews, and led the analysis. Her knowledge of the project and relation to the participants might have affected the interviews, analysis, and interpretation of the results. On the other hand, familiarity with the context can be a valuable asset and contribute to deeper discussions in the interviews, as well as a more complete understanding in the complexity analysis.

Implications for practice and research {#Sec38}
--------------------------------------

The identified implementation determinants, as well as complexity levels of different domains of the technological innovation, provide valuable insights for policy makers, managers, and health care providers and can help guide implementation and scale-up. The barriers and facilitators experienced by therapists and managers in this ICBT-i pilot implementation must be met for a successful implementation. Our findings highlight the importance of providing training, support, and