much more uncertain, with $<$E([\[N II\]]{})$>$ = 0.22$\pm$0.04 and $<$E(F502N)$>$ = 0.20$\pm$0.03. A smaller value of E(F502N, dark knots) as compared with E([\[N II\]]{}, bright gas) indicates that the dark knots do not expand as fast as the ionized gas in which they exist.

Two families of models are used to explain the origin of the dark knots found in PNe. The first [@dyson89] argues that the knots are condensations of dust and gas that originated in the extended atmosphere of the central star while it was still at the top of the Asymptotic Giant Branch. The similarity of the E values found today argue against this origin. It would be highly unlikely that knots sufficiently dense to survive the first phases of shell ejection would receive a radial acceleration thisNebula]{} can be obtained from an accurate knowledge of its dynamical properties. For homologous expansion, the relation that applies is D(pc) = (k$\rm _{1} \times {\ensuremath{\mathcal{R}}}\times cos\theta$)/(4.74 E), where k$\rm _{1}$ is the scale factor relating the spatial expansion velocity ([km s[$^{-1}$]{}]{}) to the true (not projected) distance to the central star (expressed as ), [$\mathcal{R}$]{} is the pattern velocity (the ratio of the ionization front velocity compared with the gas velocity), $\theta$ is the angle of the equatorial plane of the nebula to the sky (), and E is the expansion scale ratio. Adopting the values in O’Dell et al. (2007) of k$\rm _{1}$ = 0.65 ([km s[$^{-1}$]{}]{}/ ") and ${\ensuremath{\mathcal{R}}}= 1.34$, the relation becomes D(pc) = 179$\times$E$^{-1}$, where E is in [mas yr$^{-1}$/]{}. From this work we adopt the


[H$_{2}$]{} data taken with the LUCI1 instrument and to Zoltan Levay of the Space Telescope Science Institute for a fruitful discussion on this study. GJF acknowledges support by NSF (0908877; 1108928; and 1109061), NASA (10-ATP10-0053, 10-ADAP10-0073, and NNX12AH73G), JPL (RSA No 1430426), and STScI (HST-AR-12125.01, GO-12560, and HST-GO-12309). MP received partial support from CONACyT grant 129553. WJH acknowledges financial support from DGAPA–UNAM through project PAPIIT IN102012. CRO’s participation was supported in part by HST programs GO 12309 and GO 12543 .

[*Facilities:*]{}

Blöcker, T. 1995, , 299, 755 Capriotti, E. R. 1973, , 179, 745 Currie, D. G. et al. 1996, , 112, 1115 Dyson, J., E., Hartquist, T. W., Pettini, M., & Smith, L. J. 1989, , 241, 625 Garc[í]{}a-Segura, G., López, J. A., Steffen, W., Meaburn, J., & Manchado,them in Surat, to be taken to Agra. Surat was placed in the charge of Kalíj Khán. The emperor now advanced to Áhmedábád, where the mother of Changíz Khán came and demanded justice on Jhujhár Khán for having wantonly slain her son. As her complaint was just, the emperor ordered Jhujhár Khán to be thrown under the feet of an elephant. Muhammad Khán, son of Sher Khán Fauládi, who had fled to the Idar hills, now returned and took the city of Pátan, besieging the Mughal governor, Sayad Áhmed Khán Bárha, in the citadel. At this time Mírza Muhammad Husain was at Ranpur near Dhandhuka. When Sher Khán Fauládi, who had taken refuge in Sorath, heard of Muhammad Khán’s return to Pátan, he met Mírza Muhammad Husain, and


warnings from Mueller and Wray are influencing McConnell when it comes to legislation.

After Schumer tried to get consent to pass election security legislation, McConnell dinged Democrats for trying to slide “partisan” bills through the Senate on unanimous consent, meaning they would pass without a vote.

McConnell added that it’s “very important that we maintain the integrity and the security of our elections in this country” but that federal involvement has to be bipartisan and done with “extreme care.”

“[This is] just a highly partisan bill from the same folks who spent two years hyping up a conspiracy theory about President Trump and Russia and who continue to ignore this administration’s process at correcting the Obama administration’s failures on this subject,” McConnell said.

The Kentucky Republican has made it clear that heQ:

isolated scope two way binding is not working in angularjs

I am new to angularjs. I am working with isolated scope. The two way binding using isolated scope is not working. Please check my code. If i remove age : '=' then my code is working fine.
**HTML**

<div ng-controller="homeCtrl">
    <my-dir name="{{namee}}" age="{{age}}"></my-dir>
</div>

**JS**

var app = angular.module("home")
app.controller("homeCtrl",["$scope",function($scope){
   $scope.namee = "John";
   $scope.age= 30;
}]);

app.directive("myDir",function(){
    return{
        restrict :'E',
        scope: {
            name : '@',
            age :  '=',
        },


long-term weight loss was the most important issue. A meta-analysis published by Nguyen *et al.* showed that the mean %EWL in long-term observations (greater than 10 years) ranged from 33% to 60% \[[@cit0013]\]. The 5-year results of the present cohort were published in 2011. At that time, we reported successful outcomes (%EWL \> 50%) in 24.7% of patients after 1 year, in 31.5% after 2 years, and in 38.5% after 3 years. The increase in the number of patients who achieved %EWL greater than 50% was promising and we expected the trend to continue in subsequent years. However, the present analysis showed that only 25% of patients achieved a successful outcome in long-term observation. Previously reported success rates range from 20% to 40% among patients who maintain their24 slices each in three orthogonal orientations. The positions of the voxels were visually inspected and adjusted based on identifiable anatomical landmarks in reference to standard brain atlases. The voxel sizes were adjusted to the morphology of the anatomical target structures and were 10 × 35 × 10 mm^3^ for the hippocampus (see Fig. [1](#Fig1){ref-type="fig"}) and the middle third of the middle frontal gyrus, and 12 × 20 × 15 mm^3^ for the posterior frontomedian cortex.Fig. 1Magnetic resonance imaging (MRI) demonstrating the localization and well-adapted shape of the volume of interest (voxel size 10 × 35 × 10 mm^3^) placed in the *left* hippocampus (MR images in radiological convention) in **a** transversal, **b** coronal, and **c** sagittal orientation

All spectra were postprocessed by using the Siemens Medical Solutions spectroscopy software package on a Leonardo workstation. Following acquisition, low-frequency filtering for removal of the residual water signal


and correction for frequency shifts were performed. Data were zero-filled from 1.024 to 2.048 points. After apodization of the time domain signal by a Hanning function with 700 ms width, the data were Fourier transformed to the frequency domain. The spectra were baseline corrected with a sixth-order polynomial and first-order phase-corrected. Curve fitting to the metabolic peaks was applied using Gaussian or Lorentzian line shapes at known frequencies. Relative metabolite concentrations for N-acetyl groups (NAA), choline-containing compounds (Cho), creatine and phosphocreatine (Cre), and glutamate plus glutamine (Glu + Gln) were determined, and the metabolic ratios NAA/Cre, NAA/Cho, Cho/Cre, and (Glu + Gln)/Cre were calculated. A model MRS spectrum from one subject is presented in Fig. [2](#Fig2){ref-type="fig"}.Fig. 2Typical proton magnetic resonance spectroscopy spectrum (1H-MRS) from the *left* hippocampus

VLMT {#Sec6}
----

Cognitive performance was measured using the German versionval homozygotes (val/val). In order to address the effect of two met-alleles, met homozygotes (met/met) were compared with val homozygotes (val/val).

To make our results more comparable to other studies, we calculated the effect sizes for the results of the ANOVA (*f* values).

Results {#Sec9}
=======

The frequency of the BDNF val/val genotype in the overall sample was 65% in schizophrenia patients and 54% in patients with bipolar I disorder, and 57% in healthy subjects, which is in accordance with previously published data. Overall, the genotype frequencies were in the Hardy--Weinberg equilibrium (*P* = 0.93).

BDNF effects on hippocampal volumes {#Sec10}
-----------------------------------

The inter-rater reliability (intraclass correlation coefficient = ICC) and the intra-rater reliability for the volumetric hippocampal measurement was 0.93 and 0.99, respectively. Repeated measures MANCOVA did not reveal any significant effect of the BDNF val66met polymorphism on


structure, we were unable to replicate prior findings of a hippocampal volume reduction in carriers of the met-allele \[[@CR12], [@CR21], [@CR37]\] as we did not find any effect of BDNF genotype on hippocampal volume. Thus, this negative finding is more consistent with other recent studies which also did not observe BDNF genotype effects on structural volumes of the hippocampus \[[@CR33], [@CR41]\]. While our finding further excludes that the observed BDNF effects on MRS markers might have resulted from confounding differences in hippocampus volume (see \[[@CR41]\]), it is still possible that BDNF may also impact on hippocampal structure, but with lower effect size, which may not be observable in diagnostically heterogeneous samples. Furthermore, the results are compatible with the suggestion that neurochemical MRS markers may be more sensitive toa lesser extent, on verbal memory \[[@CR5], [@CR10], [@CR16]\]. As verbal memory tests like the California Verbal Learning Test (CVLT) and the Verbal Learning Memory Test (VLMT) may (in comparison to episodic memory tests) also impose considerable demands on prefrontal cortical functions, this may explain the lack of statistical significance for BDNF effects on the VLMT in the present study (for a similar discussion see Egan et al. 2003). Given the fact that BDNF is well-known to facilitate LTP, i.e., memory-related processes in the hippocampus \[[@CR1], [@CR5], [@CR8], [@CR10], [@CR12], [@CR21], [@CR22], [@CR36]--[@CR38]\], further studies are definitely required to clarify possible effects of BDNF genotype on hippocampus-dependent cognition. A possible bias of these results might be the effects of concomitant medication on cerebral neurochemistry. This phenomenon is being


       UPstream::msgType() = oldTag + 1;

        const AMIInterpolation& ami =
            interRegionAMI(nbrRegion, regionPatchi, nbrPatchi, flip);

        const fieldType& nbrField =
            nbrRegionMesh.lookupObject<fieldType>(fieldName);

        const fvPatchField<Type>& nbrFieldp =
            nbrField.boundaryField()[nbrPatchi];

        tmp<Field<Type>> tresult
        (
            ami.interpolateToSource(nbrFieldp.patchInternalField())
        );

             (
                    regionMesh().boundaryMesh()[regionPatchi]
                );
            mpb.reverseDistribute(regionField);
            return;
        }
    }

    FatalErrorInFunction
        << "Region patch ID " << regionPatchi << " not found in region mesh"
        << abort(FatalError);
}

template<class Type, class CombineOp>
void Foam::regionModels::regionModel::toPrimary
(
    const label regionPatchi,
    List<Type>& regionField,


  mpb.reverseDistribute(regionField, cop);
            return;
        }
    }

    FatalErrorInFunction
        << "Region patch ID " << regionPatchi << " not found in region mesh"
        << abort(FatalError);
}

template<class Type>
void Foam::regionModels::regionModel::toRegion
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    const label regionPatchi,
    List<Type>& primaryField
) const
{
    forAll(intCoupledPatchIDs_, i)
    {
        if (intCoupledPatchIDs_[i] == regionPatchi)
        {
            const mappedPatchBase& mpb =
         as to the liability or non-liability
of the public official concerned.

          It is the settled policy of this office not to write
on speculative or hypothetical questions, particularly where
no specific factual situation is presented. Accordingly, in
rendering this opinion, we are necessarily confined to giving
you a general statement of the law, without making any attempt
to cover all of the exceptions or to cover some specific
factual situation.  In this connection, we are not apprised
of whether the official, based upon the particular facts be-
fore him, is rendering a strictly ministerial decision or a


      '"Nodesignated agent of the department shall
      be liable for civil damages arising out of his
      failure to reflect liens or encumbrances on such
      motor vehicle unless such failure constitutes will-
      ful or wanton neqliqence."  (Emphasis added.) -

           In the absence of wanton or willful negligence,l

1.   Section 30, Article 1436-1, Texas Penal Code, 43 Am.Jur.
     91, Public Officers, Sec. 279, and cases cited.

                       the officer to act,6 but a contrary rule

2.   Dallas County Flood Control Dist. v. Fowler, 280 S.W.2d
     336 (Tex.Civ.App. 1955, error ref., n.r.e.); Harwell v.
     Ward County, 314 S.W.2d 868 (Tex.Civ.App. 1958, error ref.,
     n.r.e.): 43 Am.Jur. 86, Public Officers, Sec. 274, foot-
     note 13 and cases cited: Sec. 275, p. 88, footnote 3 and
     cases cited: Sec. 278, p. 90, footnote 15 and cases cited.

3.   43 Am.Jur. 88, Public Officers, Sec. 275, footnote 3 and
     cases cited.

4.   Harwell v. Ward County, supra.

5.   47 Tex.Jur.2d 167, Public Officers, Sec. 130, and cases


cited: Pridqen v. Giles, 267 S.W.2d 187 (Tex.Civ.App.
     1954, error ref., n.r.e.); Ross v. Gonzales, 29 S.W.2d
     437 (Tex.Civ.App. 1930, (error dism.); Dallas County Flood
     Control ~Dist. v. Fowler, supra; Harwell v. Ward County,
     supra; 43 Am.Jur. 85, Public Officers, Sec. 273 and cases
     cited. Set - 274, pp. 86 and 87, and cases cited; andlsee
     Am. Ry. Express v. Kentucky, 273 U.S. 269, 273 (1926).

6.   Pridqen v. Giles, supra.

                                -5480-
Hon.the record,
we agree that the district court’s grant of summary judgment was proper, and
therefore affirm. See 8th Cir. R. 47B.

      A true copy.

            Attest:

               CLERK, U. S. COURT OF APPEALS, EIGHTH CIRCUIT.

                                        -2-


working on rolling stock procurements and more construction packages coming”.

But all of this will cost a lot of money, and the government alone can't cover the estimated 3.6 trillion US dollars that will be needed by 2020 for infrastructure improvements.

Finance experts say the US has to catch up in the area of public-private sector partnerships in the infrastructure space, traditionally funded by public money.

However, the forum was not just about US needs. China's Belt and Road Initiative was mentioned many times as a way for American companies to take part in big infrastructure projects in Asia and Europe, but only if the US chooses to participate.###### Key questions

What is already known about this subject?
=========================================

-   Very little is known on the subject of quality of life (QOL) and coronary endothelial function.

-   No studies to our knowledge have specifically addressed the effects of diagnosis and treatment of coronary endothelial dysfunction on long-term QOL.

What does this study add?
=========================

-   In this manuscript we report the results of the impact of diagnosis and treatment of patients with coronary microvascular endothelial dysfunction and non-obstructive coronary artery disease (CAD) on long-term QOL.

-   These results demonstrate that among patients with chest pain and normal coronaries, the diagnosis and treatment of coronary microvascular endothelial dysfunction in those with angina pectoris and non-obstructive CAD are associated with better QOL compared with patients with normal endothelial


Although I don’t like sounding negative, it has been yet another quiet month for many bar bosses around Bangkok and from what I have seen myself and heard from my “ravers” things haven’t been much better in Pattaya either. To add fuel to the fire, there is more heat on the gogo bars from the MIB (Men In Brown), this is especially the case down in Sin City.

Where did all the big spenders go? This seems to be a question many bar owners are asking themselves. Do we sing Simply Red’s “Money’s Too Tight To Mention” as an appropriate phrase?! The clot plot thickens, as a number of folks find themselves with less and less disposable income.

When I ran Angelwitch GoGo Bar several years ago, we regularly hadpositive aspect of Bangkok’s nightlife.

The Castle Fetish Club in Pattaya opens a men only fetish club on July 1st. It is located next door and it is called Sodom. When you go there just make sure you go through the right door, or you might be in for a bit of surprise. Sounds like a good prank for a stag night to me 🙂

Mercury GoGo Bar (Middle Floor Nana Plaza) is undergoing renovations. It turns a shade of pink on July 1st, as it reopens as Mercury Ladyboy Bar.

FOR THE LATEST NEWS POSTS — CLICK HERE

My Email — davetheravebangkok@gmail.com

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Tags: Angelwitch, Bangkok Bargirls and GoGo Bars Guide, Bangkok fetish club, Dave The Rave, insanity nightclub,


 =1,
/* any depth, ? */
    CV_LOAD_IMAGE_ANYDEPTH   =2,
/* ?, any color */
    CV_LOAD_IMAGE_ANYCOLOR   =4,
/* ?, no rotate */
    CV_LOAD_IMAGE_IGNORE_ORIENTATION  =128
};

/* load image from file
  iscolor can be a combination of above flags where CV_LOAD_IMAGE_UNCHANGED
  overrides the other flags
  using CV_LOAD_IMAGE_ANYCOLOR alone is equivalent to CV_LOAD_IMAGE_UNCHANGED
  unless CV_LOAD_IMAGE_ANYDEPTH is specified images are converted to 8bit
*/
CVAPI(IplImage*) cvLoadImage( const char* filename, int iscolor CV_DEFAULT(CV_LOAD_IMAGE_COLOR));
CVAPI(CvMat*) cvLoadImageM( const char* filename, int iscolor CV_DEFAULT(CV_LOAD_IMAGE_COLOR));

enum
{
    CV_IMWRITE_JPEG_QUALITY =1,
    CV_IMWRITE_JPEG_PROGRESSIVE =2,
    CV_IMWRITE_JPEG_OPTIMIZE =3,
    CV_IMWRITE_JPEG_RST_INTERVAL =4,
    CV_IMWRITE_JPEG_LUMA_QUALITY =5,
    CV_IMWRITE_JPEG_CHROMA_QUALITY =6,
    CV_IMWRITE_PNG_COMPRESSION =16,
    CV_IMWRITE_PNG_STRATEGY =17,
  r \geq 1, 1 \leq i_1 \leq \cdots \leq i_r \}$, equipped with the sup-norm. (Note the exclusion of $e_0$. We think of 1 as $e_0$, as we will see in the definition of $\Upsilon$.) We may view $M_{\hat x}$ as a subspace of $\c S_{\hat x}$ by defining the map $\Upsilon: M_{\hat x} \rightarrow \c S_{\hat x}$ via $\Upsilon( e_i ) := e_i$ if $i \geq 1$, else $\Upsilon(e_0) := 1$. By (\[E: normalizeB\]), we may write $\Upsilon( \phi_{\hat x} e_0 ) = 1 + \eta(\hat x)$ for some $\eta(\hat x) \in \Upsilon(M_{\hat x}) \subset \c S_{\hat x}$ satisfying $|\eta(\hat x)| < 1$. Consequently, $(\Upsilon \circ \phi_{\hat x} e_0)^\kappa = \sum_{i=0}^\infty \binom{\kappa}{i} \eta(\hat x)^i \in \c S_{\hat x}$. Define the map $[ \phi_{\hat x} ]_\kappa: \c S_{\hat


$\xi \equiv 1$ mod($\pi$). Thus, the case $m = 0$ follows by writing $$1-\xi^p = (1 - \xi) (1 + \xi + \cdots + \xi^{p-1})$$ and observing that $1 + \xi + \cdots + \xi^{p-1} \equiv p$ mod($\pi$). The general case follows similarly by writing $$1 - \xi^{p^{m+1}} = (1 - \xi) \cdot \prod_{i = 0}^m (1 + \xi^{p^i} + ( \xi^{p^i} )^2 + \cdots + ( \xi^{p^i} )^{p-1}).$$

The second estimate we need is, $$| [\phi_{\hat x}]_\kappa e_{i_1} \cdots e_{i_r} | \leq | \pi^{r } |,$$ which follows quickly since $\phi_{\hat x} e_i \equiv 0$ mod($\pi$) for $i \geq 1$.

We may now prove the lemma. For $e_{i_1} \cdots e_{i_r} \in \c B$, suppose $r \leq k_m$, then $$\begin{aligned}
\left( [\phi_{\hat x}]_{\kappa; m} - [\phi_{\hat x}]_\kappa \right) e_{i_1} \cdots e_{i_r}do manage to securely hold a phone in place, but the device feels too much like a toy. It’s a hollow black plastic contraption with a glossy finish that scratches at the slightest provocation, and rough seams and pointy corners that poke me whenever I try to retrieve my device. The heads of the analog sticks feel loose, like they might break off. The Logitech PowerShell’s grippy rubberized surfaces feel far better at first, much more like a case than a controller, but it has its issues too. The power button toggle to wake the screen doesn’t work on an iPod touch. If you want to use headphones, you’ll need to carry around a special headphone adapter dongle — one issue that the Moga sidesteps by routing audio


Apple’s svelte devices. The batteries are really just there to keep your phone topped off so you can have a few hours of worry-free gaming. They do that fairly well, but don’t expect them to charge a phone that’s dead. You’ll need to plug the PowerShell into a Micro USB wall charger to get your device to charge, and the Moga actually stops charging a connected phone as soon as you plug it into the wall. Internal batteries can't justify the $100 pricetag If you keep them attached to your device, you’ll be carrying around a useless peripheral most of the time. Outside of the currently limited selection of compatible games, the gamepads do nothing at all. Even with the new iOS 7 APIs, you can’t use ato take matters into its own hands. It’s not easy to build a good game controller — Microsoft spent $100 million on the Xbox One gamepad merely to make minor improvements — and these first efforts from Logitech and Moga aren’t up to the task. While the accessory model might have worked to provide Apple with an ecosystem of cases, speaker docks, and styluses, none of those things required app developers to get involved. There’s a small sliver of Apple’s reputation at stake here if IOS game controllers fail.

Perhaps that’s why Apple never made a big deal about iOS 7 game-controller support, though. Like everything else in the accessory program, gamepads could simply be peripheral to the company’s interests, a bone to throw accessory manufacturers while it works


on things that are new and different. This summer, when games like XCOM, Deus Ex and Limbo proved that console games could be at home on mobile, game controllers — and a game console — seemed like the next logical step. But wouldn’t it be better for Apple if developers abandoned the idea of a game console, and focused on building apps for Apple’s portable touchscreen game systems instead? Game controllers are a link to the past and a way to play old games efficiently on new systems, but they reinforce the status quo. That’s not something for which Apple is generally known.

Is Apple serious about game controllers?

If I’m wrong and Apple’s serious about gamepads, the company may need to take matters into its own hands. It’s notMolecular geometry of OC···AgI determined by broadband rotational spectroscopy and ab initio calculations.
Pure rotational spectra of the ground vibrational states of six isotopologues of OC···AgI have been measured by chirped-pulse Fourier transform microwave spectroscopy. The spectra are assigned to determine the rotational constant, B(0), centrifugal distortion constant, D(J), and nuclear quadrupole coupling constant of the iodine atom, χ(aa)(I). The complex is linear. Isotopic substitutions at the silver, carbon, and oxygen atoms allow bond lengths to be established by the r(0), r(s), and r(m)((1)) methods of structure determination. The length of the C-O bond, r(CO), in the r(0) geometry for OC···AgI is 0.008 Å shorter than that found in the free CO molecule. The length of the Ag-I bond, r(AgI), is 0.013 Å shorter than in free AgI. χ(aa)(I)


new phenomenon in Uzbekistan. The Soviet system produced its own pattern of stratification and inequality. During this era, the main distinction was between the party elite and ordinary people. The Soviet elite was composed of individuals that were considered politically reliable by the center, and they were placed in the decision-making positions. In Uzbekistan, as elsewhere in the USSR, the elite consisted of the “partycrats,” the high echelons of the Communist party and leaders of Komsomol, the communist youth organization. Although the highest political positions were controlled by Moscow, the power to nominate lower-level elite was designated to the authorities in individual republics. Members of the Uzbek elite were Russified Uzbeks[1], many of whom were educated in Moscow, as well as Russians, and they were often successful inblack market, but ordinary Uzbeks interpreted this as yet another attempt by the customs officials and tax collectors to extort bribes.[21] The immediate effect of the policy was the closing down of the bazaars, and thus, the loss of income for most traders, drivers, porters, cooks and the like. The implementation of the policy was first postponed due to the protests, and then the amounts were reduced to 70 and 40 percent, respectively.

In October 2002, merchants were also obliged to have cash registers, another reason for outrage. The reasoning behind the introduction of cash registers was to track purchases and increase tax revenues. Given the level of corruption in the country, people believed it would be the relatives and clients of the President and high-ranking officials who would


have little access to information and hardly have any time to think about making changes as they struggle to make a daily living. The apathy, especially among the young people, and the exit strategy most people favor leads one to believe that the change might be slow to come. On the other hand, economic hardships and political repression provides a breeding ground for extremist Islamic movements. Yet, the current regime’s only remaining pillar is fear and repression, which may not be as strong as the Uzbek political elite think. Mere coercion can hardly keep a state intact. The question is who will be replacing them.

1. The most successful Central Asian intellectuals and politicians owed their success to their competency in Russian language and Soviet culture. No matter howtheir business, spend their money, where to buy goods and what kind to buy. They denounced the opening of some 20 markets on the borders with Kazakhstan, Kyrgyzstan, Tajikistan and Turkmenistan, where low cost goods could be bought. Deputy interior minister condemned Uzbeks traveling to neighboring states to make purchases as ‘naïve children’. [return to text]

30. See for instance Humphrey 1999, on the way collective farms worked. [return to text]

31. Uzbekistan was among the first countries to offer a base for the coalition forces. [return to text]

32. Based on official anti-Islamic materials and in the absence of fieldwork, several Western authors predicted that all Soviet Muslims would incline toward a strong Islamic identity. Moreover, incidents of ethnic strife in Central Asia in the late Soviet era led scholars


£115m in 2011, so over the past three years alone this has more than offset the cost of Red Bull's investment in F1.

But Red Bull has not been so successful across the Pond. Its Nascar stock-car racing team has struggled since joining the series in 2007 and in June it was reported that Red Bull will pull out at the end of this year. Mr Mateschitz says "this decision is not yet final but we had numerous reasons to re-analyse our involvement".

He also dashes rumours that Red Bull will sponsor the United States Grand Prix when it returns to F1's calendar next year. "As a matter of principle we are not in F1 as sponsors but are represented with our two teams."host nations and the refugees themselves, who insisted that "reintegration" was no alternative to returning to the land that now constituted the State of Israel. The dream of deferred repatriation was thus kept alive by a vast bureaucracy of dependence that has, over time, metamorphosed into a sort of mini-state unto itself and superimposed across four separate countries, including Palestine itself.

UNRWA employs 30,000 people and receives an annual operating budget of $500 million, 17 percent of which comes directly from the United States. It maintains its own schools, health clinics and welfare/social services departments and microfinance and microenterprise assistance. Although more than half of UNRWA's funding goes toward the maintenance of its Education Programme, there is every reason to believe that a self-perpetuating economy has sprung up in


 \arrow[rr, "F(g)"{name=3,description,plane={(1,0) and (0,0.7)}},bend left=30]
    \arrow[rd, "\phi_{A}"'{name=1},start anchor={[xshift=+0.5em]}]
    \&
    \&
    {\hspace{-1.25em}\usebox{\BoxNodeTwo}}
    \arrow[ld, "\phi_{B}",start anchor={[xshift=-0.5em]}]
    \\
    \&
    X
    \&
    % 2-Arrows
    \arrow[from=1,to=1-3,"\theta_{g}"{description,yshift=+0.15em},shorten=1.5em,Rightarrow,bend left=15,xshift=+0.25em,yshift=0.5em]
\end{tikzcd}
\end{document}

A:

The main idea is to combine text along path of library decorations.text with canvas is plane of library 3d. In my last answer, I have shown how to place node on specified plane by set x unit vector and y unit vector. Decoration text along path put every character in a \qboxsynced, which means  before inserting the text, the current coordinate transformation matrix is applied to the current canvas transformation matrix.
I definemade for my business. Just ONE idea from that Mastermind Group turned into a 6 figure business idea that still continue to earn money from to this day. Well worth the $3,600 ($300 X 12) investment.

I can't promise you'll have the same results. You will have to do some work. It will not be handed to you.

But I CAN Promise you this:

You will gain insights into your present business you've never had before. Opportunities you've never seen will be developed. You will enjoy working with and supporting others all with the mutual goal of growing and supporting each others businesses.

This experience isn't for everybody and those who have a limited vision of the success they can achieve may believe this is too much of a stretch.

But I know


desired outcomes from a high level mastermind group like this?

Are you currently in any other mastermind groups, or have you belonged to others in the past? If so, please tell us what you liked, or didn't like about them.

Enter Word Verification in box below *

Please complete the application and submit this form as soon as possible. You may print and fax your application securely to my inbox to: 815-550-1212.

We're looking forward to making this one of the most valuable learning and business building experiences you've ever had!Bancroft gears up for Gemboree weekend

July 31, 2018

July 31. 2018

By Nate Smelle

For more than five decades “rockhounds” and mineral collectors from around the world have been coming to Bancroft on the August long weekend for the annual Rockhound Gemboree.
Each year more than 100 vendors set up shop in Bancroft, bringing with them their collections of gems, crystals, rocks, fossils, minerals, jewelry, art and collectables.
Bancroft and District Chamber of Commerce’s general manager Greg Webb is looking forward to another exciting Gemboree weekend. He said that one of the things that makes the event such a success year after year is the eclectic mix of vendors who come to town to display and sell artifacts from their collections.
“The Bancroft Rockhound Gemboree is the largest gem and mineral show in Canada,”


each year, he said the event has become an important part of the community’s economy over the years as well.
“Visitors to Bancroft over the Gemboree period, spend over $1 million, mostly on accommodation, food and events,” said Webb.
“Merchants hire extra staff, and some stay open longer hours. Income from this time helps merchants get through the slower winter months. The Gemboree shows people why we are the ‘Mineral Capital of Canada’ and it highlights the beauty that is just beneath our feet”
The 55th annual Rockhound Gemboree will take place from Thursday, Aug. 2 through Sunday, Aug. 5 at two venues – the Bancroft Curling Club (63 Newkirk Blvd), and the North Hastings Community Centre (103 Newkirk Blvd). The four-day event will kick off with an opening ceremony toin Fig. \[fig:F\_allinone\] (a) and (b) for $\tilde{g}_+T_+/2\pi=\tilde{g}_-T_-/2\pi = 4.9\cdot10^{-3}$ feature a clear deterioration of the fidelity as $n_0$ increases, for both steps **(1)** and **(2)**. Indeed, a larger initial thermal population of phonons implies a less pure ground state, an error that propagates to the mechanical state obtained after teleportation. The counterpart of this degraded mechanical state is that the probability to obtain coincidences events after the blue pulse ($p_+$) and to obtain a photon after the red pulse ($p_-$) also increase, equally drastically. In other words the probability of the protocol to be completed is increased, but at the expense of its fidelity. The increase of $p_+$ can be understood by an approximate analytical treatment (see Appendix \[app:calcul\]), while a larger $n_0$ also implies that a


q_1\tanh q_2 F(0,1,1,1)F^*(1,0,2,0)\ket{01}\bra{10}\nonumber&\\
~\nonumber\\
+ 2|F(2,0,2,0)|^2|\beta|^2\tanh^2q_1 \ket{20}\bra{20} \nonumber\\
+ |F(1,1,1,1)|^2|\alpha|^2\tanh^2q_2 \ket{11}\bra{11} \nonumber\\
- \sqrt{2}\beta\alpha^* \tanh q_1\tanh q_2  F(2,0,2,0)F^*(1,1,1,1)\ket{20}\bra{11} \nonumber\\
- \sqrt{2}\beta^*\alpha \tanh q_1\tanh q_2  F(1,1,1,1)F^*(2,0,2,0)\ket{11}\bra{20} \nonumber\end{aligned}$$

where multiphoton states are present that degrade the computed fidelity. A parasitic term proportional to $|\alpha|^2$ induces a finite matrix element $\ket{10}\bra{10}$ even if $\beta=0$. This makes the fidelity state-dependent as discussed in App. \[app:diffreson\].\

### Realistic projectors

The above calculation is simplified since we considered ideal photon-number resolving detectors, allowing us to express $\hat{K}$ with only two-photon states. The numerical simulations presented in the main text apply instead a 50:50 beamsplitter interaction before conditioning on coincidence events in the four output modes of the Bell state measurement beamsplitter (2 polarization modes $H/V \times$ 2 spatial modes $L/R$) with the following projector, which acts after the beamsplitter:

$$\begin{aligned}
 required, which prevents from arbitrarily increasing $T_\pm$. This is shown by an analysis of the noise-equivalent phonon number $n_{NEP}$, a figure already introduced in past work [@Meenehan15]: $$n_{NEP} = \frac{\Gamma_{dark}+ \Gamma_{pump}}{\Gamma_{SB}} = \frac{\kappa^2\Gamma_{dark}}{4 \kappa_e \eta g_0^2 n_c} + A\left(\frac{\kappa\Omega_m}{2\kappa_e g_0}\right)^2$$ with $\Gamma_{dark}$ the dark-count rate of the photodetectors, $\Gamma_{pump}$ the arrival rate of pump photons that are not properly filtered and leak to the detection, $\Gamma_{SB}$ the sideband photon rate, $A$ the attenuation factor from the filter and $\eta$ the total measurement efficiency, including optical losses from the resonator to the detectors and detector efficiency. In Fig. \[fig:nNEP\], we plot $n_{NEP}$ as a function of $n_c$ and $\eta$ for the parameters of section \[section:expfeas\], but for the optical coupling, which we assume to be critical $\kappa=2\kappa_e$. We consider $A=-100$$dB$


state to teleport sits on the pole ($\alpha=1, \beta=0$ for instance), the two resonators must be placed in the phononic state $\ket{01}$. There should be zero horizontal component in the polarization of the output photon after the red pulse, which is not possible since the true phononic occupancy of $\text{OM}_1$ is always larger than 0. In contrast, teleporting an equatorial state $|\alpha| = |\beta|$ is easier because the photon we expect has equal horizontal and vertical polarization components, which is naturally achieved in our balanced Mach-Zehnder configuration. This subtle effect is larger as the mean initial phonon occupancy of the disks grows, and the states that are easier to read-out shift away from the equator as we introduce an imbalance in the initial occupancy of the two disksthe primitive structure of the carbon filler. However, the most relevant aspect of this work concerns the achievement by the previously mentioned catalytic system, of polymers with a pyrene as a chain terminal. These terminals can provide interaction with the carbon fillers and facilitate the dispersion of the latter in the polymer matrix. The employment of the non-oxidized filler may allow all of the previously mentioned interesting carbonaceous material applications \[[@B2-polymers-11-01261],[@B3-polymers-11-01261],[@B4-polymers-11-01261],[@B5-polymers-11-01261],[@B6-polymers-11-01261],[@B7-polymers-11-01261],[@B8-polymers-11-01261],[@B9-polymers-11-01261],[@B10-polymers-11-01261],[@B11-polymers-11-01261],[@B12-polymers-11-01261],[@B13-polymers-11-01261],[@B14-polymers-11-01261],[@B15-polymers-11-01261],[@B16-polymers-11-01261],[@B17-polymers-11-01261],[@B18-polymers-11-01261],[@B19-polymers-11-01261],[@B20-polymers-11-01261],[@B21-polymers-11-01261],[@B22-polymers-11-01261],[@B23-polymers-11-01261]\].

2. Materials and Methods {#sec2-polymers-11-01261}
========================

2.1. Materials {#sec2dot1-polymers-11-01261}
--------------

All the reactions were carried out in nitrogen atmosphere using standard Schlenk or glovebox techniques. All the reagents used in this study were of reagent grade quality and sourced from Sigma-Aldrich s.r.l. (Milan, Italy). These reagents were used as received. The solvents were dried and distilled before use. Deuterated solvents were degassed


mixture was stirred for 2 h at room temperature, then it was filtered and washed with dry CH~2~Cl~2~ (40 mL). The product was recovered and dried in vacuo overnight. Yields 1.09 g.

### 2.3.5. Evaluation of the Amount of Ru-Based Catalyst Supported on Graphite {#sec2dot3dot5-polymers-11-01261}

The amount of Ru linked to graphite was evaluated by (TGA). The analysis was performed in air flow to allow the Ru to oxidize in the form of ruthenium oxide (RuO~2~). From the residue at 1000 °C, it was possible to calculate the amount of supported catalyst: 6.01 × 10^−8^ mol/mg.

### 2.3.6. ROMP of the 2-Norbornene and 1,5-Cyclooctadiene {#sec2dot3dot6-polymers-11-01261}

In a typical experiment, a solution of initiator (HG2~pyrene~ or HG2) or suspension of graphite-HG2~pyrene~ (see [Table 1](#polymers-11-01261-t001){ref-type="table"}) in tetrahydrofuran (1 mL) was mixed with a stirredTPMS sensor checks the difference between set pressure and the actual pressure. 30 or 34 does not show anything. Inflate the tires again to correct pressure and reset the TPMS when car is stationary and then drive until TPMS is set. If it doesn't set, visit your dealer.


Welcome to the 2nd Blockstack Berlin Meetup. Last time, Blockstack partnered with IPFS and this time we're partnering with IPDB for a joint meetup in Berlin!

Some of the Blockstack developers are in town for the Tech Open Air festival and in the spirit of TOA we'll have a technical discussion on blockchains followed by drinks.

This event is for anyone interested in decentralized Web, ownership of your data, building user-controlled applications, Internet security, scaling decentralized databases, and of course blockchains like Bitcoin and Ethereum.

Schedule (tentative):

(a) An introduction to Blockstack (http://blockstack.org/), the blockchain application stack with services for naming, identity, authentication, and storage.

(b) Overview of IPDB (http://ipdb.foundation), a planetary-scale blockchain database and how caretaker nodes work.

(c) Discussion of the recent DAO attack on Ethereum and difference between simple contracts andsimple but effective method is described not only to improve the moisture content of the ground meat product, cooked or uncooked, but to provide an improved ground meat product having exceptionally eating qualities. In co-pending patent applications, commonly assigned, as the present application, U.S. Ser. No. 704,500, filed May 23, 1991, now U.S. Pat. No. 5,149,551, and U.S. Ser. No. 811,192 filed Dec. 21, 1991 a finely divided special type of calcium citrate is described as an anticaking agent for dry fructose-containing beverages in the first mentioned patent application and this special type of calcium citrate is also described in the second mentioned patent application as useful for opacifying and whitening aqueous food compositions. It has been discovered that this special calcium citrate added to ground meats provided


heavens declare the glory of God

The sky displays what his hands have made

One day tells a story to the next

One night shares knowledge with the next

Without talking, without words

Without their voices being heard

Yet, their sound has gone out into the entire world

Their message to the ends of the earth

– Psalm 19:1-4, God's Word Versionwere raised in urban settings with little access and exposure to nature. At the same time, they've faced a lot of traumatic circumstances—broken homes, incarceration—and they need different forms of therapy," Jones, a longtime teacher and health counselor, tells mbg. "Outside standard counseling, nature can act as an informal but very effective method of therapy. Without realizing it, it helps them heal from a lot of the trauma they've experienced. Outside, kids are able to have a refuge of peace—away from a lot of the things they may be facing at home."

Article continues below

How to raise a nature-hungry kid.

If you're a parent or educator looking to give your kids more access to nature's medicinal benefits, even in a dense city, Milligan-Toffler has some tips:

"Adopt" a place close to


unclear. We should try to stay with the
original language (or, perhaps, limit expansion of the termination right to
circumstances when a "required" approval is revoked.) While the broadened
termination right proposed by Peoples is available to either party, I
wouldn't think it likely that MEH would wish to terminate as a result of a
modified regualtory decision not required for continuation of the agency
arrangement.
2. Sects. 1.6, 7.1. 2.2, 2.10 (comments re cumulative net revenue
definition) As modified, MEH is charged with the duty to market Hub
Serivces, which includes Extended Hub Serivces (Def'n. 1.17). However, the
proposed Adminisatrative Service Fee (7.1) is only payable during the term
of the Agreement. MEH, therefore, is required by the Agreement to market
extended Hub Services, but receives no compensation (after termination of
the Agreement) for doing so. Also, Peoples proposes topoint for displacement delivery. Northern Illinois Gas Co. did
agree to these provision in the contract with its Hub Agent. I do not know
the value of these commitments to MEH from a business standpoint.
                         4. Sect. 1.13. Peoples proposes that the GTC be
defined to included changes made by Peoples in its sole discretion.
Peoples, however, is not free to change the GTC as it sees fit. FERC may
elect to allow changes proposed by Peoples to become effective, but Peoples
can, at most, "propose" changes in its sole discretion. How about: "the
effective general Terms and Conditions of the Operating Statament as may be
modified from time to time." Sect.


with much throughout its history. Many of those qualities came and went. But one remains. The great scholar Ibn 'Aqil once said: "If you want to assess the value of Islam in the hearts of the people of the times, do not look to their crowding of the entrances of mosques or their shouting to answer the call to Hajj. Rather, look to their confronting the enemies of the Shari'ah."

The Muslims being gassed, shot, and burned to death by secularists today in the streets and mosques of Cairo, Alexandria, and elsewhere are being targeted for just one reason: Islam. And what is happening is not but the latest in a series of events stretching far back into Egyptian history, which is replete with the stories of men andunder the khilafah of 'Umar. The jizyah was paid, and the very first mosque on the African mainland was built near Cairo, at the apex of the triangle formed by the Nile Delta. Egypt soon became one of the strongest centers of Islamic knowledge - a hub for scholars and worshippers. 'Uqbah bin 'Amir was the Companion who had the most influence on Egypt in terms of knowledge, and Egyptians loved him and learned much of the Sunnah from him. It also became one of the most favored bases for the Mujahidin of the Salaf. The great Imam al-A'raj (the close companion of Abu Hurayrah) said: "The best coastline at which to perform Ribat is that of Alexandria," and Sufyan bin 'Uyaynah once said regarding Alexandria: "It is


of Syria. Look, for example, at how Genghis Khan entered the city of Marw (Merv, Turkmenistan): "The Mongols then headed for Marw with Genghis Khan. Nearly 200,000 fighters consisting of Arabs and others were camped around it to defend it. They fought fiercely until the Muslims were beaten." They then "laid siege to the city for five days, and gave its governor a false promise of safety. When he came out, they betrayed him and the people of the city. They killed them, plundered them, enslaved them, and subjected them to various forms of torture. All in all, they killed 700,000 human beings in a single day."

He described that "people were utterly terrified of them, to the point that if just one of them entered a part ofhe was eventually captured by the French and taken to a prison in Cairo. A ransom was demanded for him that was so high that it was impossible to pay. Napoleon then had him executed.

* While occupying Egypt, Napoleon had built a prison: the notorious Liman Turah. A little over a century and a half later, a frail, middle-aged man found himself in the depths of this prison. His body still scarred from the abuse by his torturers, the man sat up in his cell and began to write. The words which flowed from his pen over the following decade sitting in that prison changed the world outside its concrete walls, continued to do so through the following decades, and still do so today. That man was Sayyid


how she learned that he had been killed: "My friend's son - who was also the friend of 'Abd ar-Rahman - was killed there. So, I posted the news on Facebook. Suddenly, people began posting responses informing me that my son had also been killed.""

The article then shifts to another: "With her simple black village clothes, she frantically searched the bodies laid out on the floor of the mosque, while repeating in her village accent: "Where are you, 'Imad? Where did you go, my son? Where did you go and leave me all alone?" She is the mother of the 15-year-old child 'Imad Hamdi, from the province of Fayyum (southwest of Cairo). She was unable to identify which body was her son's due to the dozens of bodieswooden flooring, a dining table, a stunning armoire, personal bar, satellite TV, tea and coffee maker, high-speed Internet connection and 24-hours in-room dining along with a large balcony.

Theme evenings are a memorable way to entertain and reward your clients or colleagues. For example, Bedouin night will take you and your guests by camel to dinner at a desert encampment by the pyramids followed by a display of exotic dancing. One of those nights to remember…

Fitness & other sports

Outdoor swimming pool

Fitness Centre

Outdoor tennis courts

Jogging track

Horse riding

Golf (see www.egyptgolftours.com)There is a historical 9-hole golf course right on the doorstep, with distracting views of the pyramids.


the fur coat if it is more than confident when getting sized for a dress became intimately and can find the ones she pens down on state property of mink oil for leather was used for clothing when there are still remains open for debate.

Then, in 1998, HBO introduced in 1929, and became a popular attires that occupy place in wardrobe of almost every brand of shoe maker has never gone out of style with them, but these days nutria, which is worn too forward young men and women. Hippies were born and collections in terms of stylish caps like IDA, People for the attention to womens clothing items. For example a synthetic material which you Best KITPIL31020SMD75571 – Value Kit – Smead File Jacket With 2-Ply Taband distinct control box should be avoided. Additionally, in the event the separate control box fails, the entire energy storage system is unable to function.
Thus, there is a need for improvement in this field.


1999                 Decided:   January 19, 1999

Before WIDENER, MURNAGHAN, and ERVIN, Circuit Judges.

Dismissed by unpublished per curiam opinion.

James Terry Little, Appellant Pro Se. Benjamin H. White, Jr., As-
sistant United States Attorney, Greensboro, North Carolina, for
Appellee.

Unpublished opinions are not binding precedent in this circuit.
See Local Rule 36(c).
PER CURIAM:

     James Terry Little appeals the district court’s order denying

his motion filed under 28 U.S.C.A. § 2255 (West 1994 & Supp. 1998).

Little’s case was referred to a magistrate judge pursuant to 28

U.S.C. § 636(b)(1)(B) (1994).     The magistrate judge recommended

that relief be denied and advised Little that the failure to file

timely objections to this recommendation could waive appellate

review ofAir Meds, L.L.C. v. Cutter Aviation, Inc., 198 Ariz. 10, 15, ¶ 27, 6 P.3d 315, 320 (App. 2000), "[t]he existence of a contract that merely puts the parties within tortious striking range of each other does not convert ensuing torts into contract claims." Put differently, "[w]hen the duty breached is one implied by law based on the relationship of the parties, that claim sounds fundamentally in tort, not contract." Id. at 15, ¶ 27, 6 P.3d at 320.
¶ 12 On the other hand, when "the duty breached is not imposed by law, but is a duty created by the contractual relationship, and would not exist `but for' the contract, then breach of either express covenants or those necessarily implied from them sounds in contract." Barmat, 155 Ariz.


held by only the plaintiffs and defendants, they operated more as partners than in strict compliance with the corporate form. In such circumstances, the plaintiffs had standing, both derivatively and directly, to sue . . . for an accounting.
Id. at 412, 621 P.2d at 918, overruled on other grounds by Turley v. Ethington, 213 Ariz. 640, 647, ¶ 27, 146 P.3d 1282, 1289 (App.2006). While Arizona created the statutory close corporation in 1976, A.R.S. §§ 10-1801 through -1818 (added as § 10-201 et seq. by 1976 Ariz. Sess. Laws, ch. 62, § 1 (2nd Reg. Sess.); renumbered as §§ 10-1801 through -1818 by 1994 Ariz. Sess. Laws, ch. 233, §§ 8, 17 (2nd Reg. Sess.)), the statutes did not displace the common-law doctrines applicable to closely-held corporations. Seerabbit serum from Agro Bio as a control and the following antibodies: anti-MYH9 (Covance, 1/250), anti-CD11c (HL3 clone, 1/100) and anti-I-Aβ^b^ (AF6-120.1 clone, 1/100). For lentivirus production, HEK cells were transfected using GeneJuice (Novagen).

DC imaging on epidermal ear sheets
----------------------------------

Epidermal ear sheets were removed from the ear ventral part, as previously described[@b44]. They were stained by adding anti-LYVE-1 in the culture medium for 1 h at room temperature. In the meantime, *WT* and *myosin IIA*^*−/−*^ DCs were stained with CFSE 5 μM and CMTMR 5 μM at 10 millions per ml in PBS for 20 min at 37 °C, incubated for 5 min at 37 °C in serum and washed twice in the culture medium. Overall, 20,000 cells of each cell type were mixed and loaded on the stained epidermal sheet. After 4 h at 37 °C, epidermal


the first 15 min, medium alone was loaded into the tank tips filling the microfluidic chambers. It was then removed and replaced by medium alone on one chamber and drug-containing medium on the opposite chamber. This resulted in the formation of a gradient in the microchannels that connect the two fluidic chambers. Cells were recorded during 40 min post loading. Clogging of microchannels by one cell impaired gradient formation but resulted in the selective delivery of the drug to one cell side. Migrating cells were imaged using a wide field video-microscope Nikon TiE microscope equipped with a cooled CCD camera (HQ2, Photometrics) with a × 10 Ph 0.3 NA. Cell instantaneous velocities were calculated for each cell before and after drug delivery. To avoid artefacts induced by flow, the firstto the one used in macropinocytosis assays. In all, 10^5^ cells per well were loaded and left overnight to allow their spontaneous entry into microchannels. Just before image acquisition, OVA coupled to AlexaFluor-488 and CypHer5E was added, and cells were immediately imaged using an epifluorescence video-microscope Nikon TiE microscope equipped with a cooled CCD camera (HQ2, Photometrics) with a × 10 or × 20 objective during 90 min. Movies were quantified using either Imaris 7.2.3 or the Integrated Morphometry Analysis tool of Metamorph (Molecular Devices). The CypHer5E signal was used as a mask and applied on the AF488-OVA signal at different time points. The amount of OVA accumulated in endolysosomes was normalized by the amount of OVA taken up at the cell front. To address the impact of macropinocytosis


To take only into account myosin IIA enrichment above background, myosin IIA patches were considered as clusters bigger than 10 pixels above the mean GFP intensity of the cell front GFP cytoplasmic signal.

Flow cytometry analysis
-----------------------

Cells were resuspended in staining buffer (see above). After Fc blocking with 24G2 monoclonal Ab, the cell suspension was stained for 20 min at 4 °C with the indicated antibodies. Cells were then washed three times and were resuspended in staining buffer. For intracellular staining, cells were first surface-stained as described above, and then permeabilized, fixed and stained with anti-Myh9 or rabbit serum using the Cytofix/Cytoperm kit from BD Bioscience as recommended by the manufacturer.

Lentivirus production and infection
-----------------------------------

For short hairpin RNA (shRNA) experiments, purified pLKO.1 lentiviral plasmids carrying shRNA sequences for Ii (NM_010545.2-718s1c1-CCGGGCGTCCAATGTCCATGGATAACTCGAGTTATCCATGGACATTGGACGCTTTTTG for ShIi1 andwashes in PBS, PDMS was gently removed and cells were permeabilized in PBS 1 × +0.2 %+BSA+0.05 % saponin for 10 min and stained with antibodies. All washes and antibody dilutions were performed in the permeabilization buffer. Slides were washed, mounted and visualized on an inverted Spinning Disk Confocal Roper/Nikon microscope with a × 63 1.4 NA or a × 100 1.4 NA oil immersion objective.

Duo-Link *in situ* detection of protein complexes
-------------------------------------------------

The Duo-Link *in situ* experiment was performed according to the manufacturer\'s recommendations (Olink Bioscience). Briefly, immature DCs were loaded in microchannels, fixed and permeabilized as described in the *Immunofluorescence* section. DCs were stained with primary antibodies in permeabilization buffer overnight at 4 °C, washed once with the permeabilization buffer, stained with AlexaFluor488-Phalloidin for 30 min and washed again before the


of Health, Bethesda, MD, USA, <http://imagej.nih.gov/ij/>, 1997-2012) and UnwarpJ plugin[@b46]. Co-localized pixels were detected using the RG2B co-localization plug in of Image J.

Immunoblotting
--------------

DCs were lysed for 10 min in 100 mM Tris, 150 mM NaCl, 0.5% NP-40, a protease inhibitor cocktail (Roche) and a phosphatase inhibitor cocktail (Sigma). Soluble extracts (50 μg) were loaded on a 4--20% TGX gradient gel (Bio-Rad) and were transferred on a Trans-Blot Turbo PVDF/Nitrocellulose membrane (Bio-Rad). Membranes were blocked with TBS−0.05% Tween-20+5% BSA, incubated with primary antibodies (1/1,000 anti-phosho-MLC and 1/5,000 anti-α-tubulin), washed and incubated with secondary antibodies (1/5,000 horseradish peroxidase (HRP)-conjugated antibodies). Signals were revealed with the SuperSignal West Dura substrate (Thermo Scientific).

Myosin IIA-GFP pull-down
------------------------

For each condition, 5 × 10^6^ BMDCs transfected at day 6 were lysed 8 h post transfection at 4 °C in 25 mM Tris pHPICT IBiSA Nikon imaging centre (CNRS UMR144, Institut Curie), the Curie animal facility, O. Malbec and F.X. Gobert for technical support, A. Chaillet for his help with image analysis, H. Ploegh and O. Bakke for providing *I-A*^*b*^*β-GFP* mice and human Ii constructs, respectively. M.C. and M.L.H. were supported by fellowships from the Fondation pour la Recherche Médicale and the Association pour la Recherche contre le Cancer, respectively. This work was funded by grants from the City of Paris and the European Research Council to A.-M.L.-D. (Strapacemi 243103), the Association Nationale pour la Recherche (ANR-09-PIRI-0027-PCVI) and the InnaBiosanté foundation (Micemico) to A.-M.L.-D., M.P. and R.V., and the DCBIOL Labex from the French Government (ANR-10-IDEX-0001-02-PSL\* and ANR-11-LABX-0043). The super-resolution SIM microscope was funded through an ERC Advanced Investigator Grant (250367)


intensity of the fluorescent OVA signal measured at the cell front. Data were obtained from 23 cells showing at least one event of myosin IIA-GFP at their front (four independent experiments).](ncomms8526-f6){#f6}

![Regulation of macropinosome dynamics by myosin IIA facilitates antigen transport to endolysosomes.\
(**a**) Experimental design to monitor antigen transport to endolysosomes using OVA coupled to both AF488 (green) and CypHer5E (red). Arrows indicate the direction of migration. (**b**) Sequential wide field microscopy images (× 20, one image every 2 min) of WT, myosin IIA^*−/−*^, Ii^*−/−*^ and CatS^*−/−*^ immature DCs migrating along microchannels filled with AF488-OVA-CypHer5E. Scale bars, 10 μm. (**c**) OVA accumulation into endolysosomes in migrating myosin IIA^*−/−*^ versus WT DCs (left), Ii^*−/−*^ versus WT DCs (middle) and CatS^*−/−*^ versus WT DCs (right) immature DCs, quantified as AF488-OVA sum intensity accumulatedmaladministration and weak
government. (fn. 23) Under the rule of Abbot Henry
de Munden, the prior, William de Haswell,
had exercised, or perhaps usurped, great power,
and it is likely that he held the office of treasurer.
At the visitation he was accused of being a
drunkard, to the damage of the house and the
scandal of many. He was negligent and remiss
in spiritual and temporal matters, being himself
a man of evil life. Discipline was relaxed, and
he was charged with having spent a great part of
the substance of the house on his kinsfolk; with
alienating the silver vessels and ornaments of the
church; with pledging the credit of the house
for debts of other persons. The bishop was told
that owing to his conduct the monastery was so
seriously embarrassed that the most discreet abbot
would find difficulty in redeeming its


understanding that Adam de Brokenborough
was 'a discreet man, esteemed for his learning
and virtuous habits and actions . . . and circumspect in spiritual and temporal matters,' he
collated him to the office of abbot. (fn. 32) The penalty
for disregard of the statute of mortmain was
heavy, and in 1313 the abbot and convent were
compelled to pay a fine of £200 for the royal
pardon because they had received a number of
parcels of lands, tenements, and shops in Cirencester without the late king's leave to acquire
them in mortmain. (fn. 33) In 1314 they paid another
fine of £20 for obtaining the appropriation of
Ampney St. Mary from Bishop Giffard without
licence, (fn. 34) and £5 for acquiring lands in Minety in
mortmain in the reign of Edward I. (fn. 35) Heavy
law costs were incurred in defendingof round and join yarn in 12th dc.

**Little finger** 1ch, 1dc in same dc as join, 1dc in each of next 8dc, 2ch, ss in first dc. Complete little finger as left glove, then work remaining fingers to match.
Granny Square Hat

Whip up six granny squares and join them together to make this fun hat. If you have lots of yarn to choose from, you can work out a planned colour scheme; or with leftover scrap yarns enjoy combining the colours freestyle.

**ESTIMATED TIME TO COMPLETE**

5 hours.

**ABOUT THIS YARN**

Use pure wool or wool rich mix DK yarns in any colours you like. Just make sure that the yarns can all be washed the same way.

**SIZE**

**Circumference** 56cm (22in)

**YOU WILL NEED**

  Approximately 70g of pure wool or wool mix DK yarn


in 3rd ch. 66 sts.

Changing colours as desired, work 3 rounds dc, then cont in A.

**Round 11** 3ch, 1tr in each of next 3dc, 3trtog, [1tr in each of next 8dc, 3trtog] 5 times, 1tr in each of last 4dc, ss in 3rd ch. 54 sts.

**Round 12** 3ch, [1tr in each tr] to end, ss in 3rd ch.

**Round 13** 3ch, 1tr in each of next 2tr, 3trtog, [1tr in each of next 6tr, 3trtog] 5 times, 1tr in each of last 3tr, ss in 3rd ch. 42 sts.

Changing colours as desired, work 3 rounds dc, then cont in A.

**Round 17** 3ch, 1tr in next dc, 3trtog, [1tr in each of next 4dc, 3trtog] 5 times, 1tr in each of last 2dc, ss in 3rd ch. 30 sts.

**Round 18**As a result, a broad range of physiological, behavioral, and morphological features have been shown to affect predator--prey interactions (Lagrue, Besson, & Lecerf, [2015](#ece36332-bib-0045){ref-type="ref"}; Portalier, Fussmann, Loreau, & Cherif, [2019](#ece36332-bib-0060){ref-type="ref"}). Furthermore, predation outcomes are often dependent on the combination of certain traits of the species involved (Barrios‐O\'Neill et al., [2016](#ece36332-bib-0005){ref-type="ref"}; Barrios‐O\'Neill, Kelly, & Emmerson, [2019](#ece36332-bib-0006){ref-type="ref"}; Christensen, [1996](#ece36332-bib-0013){ref-type="ref"}; Einfalt, Parkos, & Wahl, [2015](#ece36332-bib-0026){ref-type="ref"}; Kolář, Boukal, & Sentis, [2019](#ece36332-bib-0044){ref-type="ref"}; Uma & Weiss, [2012](#ece36332-bib-0084){ref-type="ref"}).

Body size is an important trait that is strongly linked to foraging outcomes. For instance, in fish, bigger predators often have greater prey capture success owing to enhanced swimming abilities, improved visual acuity, and changes to morphology such as increased gape (Christensen, [1996](#ece36332-bib-0013){ref-type="ref"}; Graeb, Mangan, Jolley, Wahl, & Dettmers, [2006](#ece36332-bib-0032){ref-type="ref"}; Miller, Crowder, & Rice, [1993](#ece36332-bib-0051){ref-type="ref"}). Similarly, larger prey size permits greater reaction distances, faster escape speeds, and often provides


by handling times (Jeschke, Kopp, & Tollrian, [2004](#ece36332-bib-0041){ref-type="ref"}); type II functional responses are hyperbolic, whereby most, if not all, resources are consumed at low densities and consumption rates are restricted at high densities by handling time; sigmoid type III functional responses allow for refuge at low densities as attack rate increases with prey density, before feeding rates again saturate at high densities. While the type II functional response is thought to be more destabilizing for prey populations and may lead to local extinctions, type III curves may stabilize resources (Juliano, [2001](#ece36332-bib-0042){ref-type="ref"}).

The aims of this study were to investigate intra‐ and interspecific resource use variations as a function of the relative predator body size of bluegill and largemouth bass toward a common fish prey species. Using functional responses, we quantified predator--prey          0.018 ± 0.001, 11.05 ± 0.05   0.035 ± 0.002, 14.65 ± 0.19   0.075 ± 0.004, 18.50 ± 0.14
  Cage dimensions (cm, L)   24.5 × 23.0 × 23, 12.9        27.0 × 26.8 × 26.8, 19.4      29.5 × 29.5 × 29.5, 25.6

Cage dimensions (height × breadth × width cm) and volume (L), scaled for length of predator, are also presented.

John Wiley & Sons, Ltd

Bluegill and largemouth bass of each size class (Table [1](#ece36332-tbl-0001){ref-type="table"}) were starved for 72 hr, before being randomly selected from their holding tanks and transferred to the appropriate size‐scaled cage (see above) 1 hr prior to a trial. Pilot observations indicated that this was sufficient time for fish to settle in cages before consuming prey. Individual fish were then presented with one of three sizes of tilapia prey (Table [1](#ece36332-tbl-0001){ref-type="table"}) at


invasive fish toward their prey. Furthermore, they show that body size scalings can interact and manifest differently between predator species and potentially drive differential invader impacts.

We found that all size classes of both bluegill and largemouth bass exhibited a saturating type II functional response toward each size class of tilapia prey. However, there were marked differences in predation rates between the species, and predator--prey interactions differed within intraspecific body size ratios. Predation by largemouth bass was generally greater than in bluegill across all body size ratios examined here which was expected given the reported voracity of bass (e.g., Alexander et al., [2014](#ece36332-bib-0001){ref-type="ref"}). However, the higher predation of largemouth bass was most pronounced at small and intermediate predator sizes, and became less important where large individuals of both predator fish speciestypes simultaneously is required to elucidate selectivity or switching processes which may stabilize trophic interactions (e.g., Cuthbert, Dickey, McMorrow, Laverty, & Dick, [2018](#ece36332-bib-0018){ref-type="ref"}), given that prey types were provided singularly in the present study.

The application of functional responses offers useful insights into the density dependencies of interaction strengths comparatively (Jeschke, Kopp, & Tollrian, [2002](#ece36332-bib-0040){ref-type="ref"}; Wasserman, Alexander, Weyl, et al., [2016](#ece36332-bib-0089){ref-type="ref"}). While such comparisons can be difficult to parallel with empirical community dynamics (Vonesh, McCoy, Altwegg, Landi, & Measey, [2017a](#ece36332-bib-0086){ref-type="ref"}, [2017b](#ece36332-bib-0087){ref-type="ref"}), functional responses offer comparative insights into the influence of context dependencies on predatory impacts (Sentis & Boukal, [2018](#ece36332-bib-0076){ref-type="ref"}; Sheath et al., [2018](#ece36332-bib-0078){ref-type="ref"}; Wasserman, Alexander, Dalu, et al., [2016](#ece36332-bib-0088){ref-type="ref"}). Our findings demonstrate effects of body size ratios on the predatory interaction strengths between piscivorous fishes and their prey. Moreover, we show clear consumptive differences between


two key invaders which may relate to differential impacts on prey across their ontogeny. While traits other than body size can influence interaction strengths (e.g., temperature: Cuthbert, Dick, Callaghan, & Dickey, [2018](#ece36332-bib-0016){ref-type="ref"}; Englund, Öhlund, Hein, & Diehl, [2011](#ece36332-bib-0028){ref-type="ref"}; Sentis, Hemptinne, & Brodeur, [2013](#ece36332-bib-0077){ref-type="ref"}), effects of body size have been shown to be particularly pervasive across trophic and taxonomic groups (Barrios‐O\'Neill et al., [2016](#ece36332-bib-0005){ref-type="ref"}; Brose et al., [2019](#ece36332-bib-0011){ref-type="ref"}). The present study furthers these findings, highlighting the importance of both inter‐ and intraspecific differences in predator--prey body size ratios for trophic interactions. Therefore, asynchronous ontogenic development between predators and prey likely affect community outcomes with respect to population stabilities. We thus propose that considerations for the intra‐ and interspecific scaling of body size in consumer--resource systems can greatly enhance our predictive capacity for community interactions, invasive species1. They are unknown in the most popular community for designers, Dribbble:

Cosmin Capitanu – “I’m a freelance graphic designer, an architect, and an urban planner.”

Ionut Zamfir – Product Designer at Zomato

Virgil Pana – “Freelance designer specialized in UI and interaction design.

Paul Flavius Nechita – “Lazy designer & shop keeper @ creativemarket.com/TheUIShop”

2.They don’t even know how to create useful themes to sell them on popular marketplaces:

Themeisle – Discover 30+ Free & Premium WordPress Themes & Templates

Pixel Grade – “We build smart themes for productive people”

Get Bowtied – The team of choice for reliable WordPress themes.

3.They create only crappy art. See for yourself:

Aitch – “I create colorful watercolor artworks on paper, characters cut out of wood, painted murals and intricate patterns and illustrations for clients all over the world.”

Madalina Andronic


– Since 2010, Madalina’s freelance work includes projects for clients all around the world and 4 published books in Romania and UK.

Octavian Belintan – Colorblind is a multidisciplinary design studio located in Bucharest / Romania. I collaborated with numerous companies (big and small) and agencies.

4.They are so limited that they don’t even do research before starting their work:

Great article written by Alexandru Paduraru.

5.They work in dreary offices:

Ezzo Design Office

E-spres-oh Office

Impact Hub Office

Fortech

Betfair

Steelcase

6.They turn ideas into products that nobody uses or wants:

With a worldwide network of 500 million machines, Bitdefender has the largest security delivery infrastructure on the globe. Performing 11 billion security queries per day, Bitdefender detects, anticipates and takes action to neutralize even the newest dangers anywhere in the world in as little as 3 seconds.

Avangate powersof things we actually need and would personally use inside our web projects. They power businesses and individuals to create better-looking web projects around the world.

Increase Media – A creative digital media agency working for amazing business and brands worldwide

Increase Media is the perfect sweet spot between utterly creative and strongly analytical. They offer well executed digital strategy that creates both sales and happiness.

8.They are expensive as f***:

Romania is the cheapest technology hub.

Coders get less than $20 / hour

9.The world’s greatest companies just hate them:

10.They don’t know how to make a Indiegogo campaign:

Sound Heroes: Bluetooth Speaker of the Future

Raised over $450k on Indiegogo

This article is obviously written in an ironic manner, we are really proud of our Romanian colleagues! And we strongly recommend working with our fellow Romanian


Laguna de Tacarigua National Park

The Laguna de Tacarigua National Park () Also Tacarigua Lagoon National Park Is a protected area with the status of a national park located east of Miranda State, in the South American country of Venezuela. It comprises a permanent coastal lagoon of 7800 ha and 1.2 m of average depth, separated from the sea by a restinga or coastal barrier of 28.8 km long and 300–1000 m wide that was formed by the action of the sea current Which runs along the coast in an East-West direction.

To the south of the lagoon extends an area dominated by dry forests and to the north, a marine area of 20,700 ha. In total the park covers 39,100 ha. Approximately 4,000 ha of the park are covered byWe arrived late at night in Huimin. Our goal was the Jingmai ancient tea growing area, but it was too dark and late by the time we arrived. We got an early start and made our first focus on breakfast. Breakfast in small Chinese villages is largely hit or miss, with the hits generally being noodles. I'm not a big fan of noodles in the morning, but the practice is growing on me. My idea of the perfect breakfast is some fresh brewed shou puerh with a side of peanut butter toast. Finding decent bread, let alone peanut butter is an impossible task outside of the larger cities in China. For situations like this I allow my wife's expertise to take over. She has a native ability to


the tea tree leaves brought a cool breeze announcing Spring with a sweet aroma. The suns rays piercing the upper forest canopy with the slowly swaying branches performed a shadow puppet show on the forest floor to entertain us. It was a singular moment that I won't soon forget.

A few of these trees were over a thousand year old and were as large as the apple trees of Eastern Washington I used to climb as a kid. The first Spring rains had yet to provide a drink to this thirsty mountain. Thus it was just a bit too early in the year for the harvest of these ancient tea trees. A few trees presented us with their first buds and Tang encouraged us to pluck them to eat.I was once told not too look at nora's castle welp he's gonna kill me anyways

I do love the color scheme you went very Nora (Norish? Noraien? ) and I like how the crown is made of electricity ( wouldn't it mean she would always be strong since SHE'S QUEEN OF THE CASTLE!) her expression reminds me of a random girl who just got told she was queen of a castle and placed a crown on her (which is pretty good, since i like that kind of plot and stuff (づ｡◕‿‿◕｡)づ) and as Alex said yeah the body looks different like I think the back could be more smoother but I understand that it's kinda difficult to do that ( me myself I've tried and it looked like


Warszawa Zachodnia-Katowice railway line

Railway line 1 is a double-track, electrified railway line running across the Masovian, Łódź and Silesian Voivodeship, and as such serving as the main railway artery between Warsaw and Katowice.

Route plan

References

Category:Railway lines in Poland11 exons and 10 introns, updated on 30 November 2014) \[[@B20]\]. Seven different sirtuin (SIRT) proteins in humans (SIRT1-7) are known to possess cardioprotective properties, including the regulation of vascular endothelial homeostasis, angiogenesis, endothelial senescence, and endothelial function through the modulation of endothelial nitric oxide synthase activity \[[@B20]--[@B23]\]. The resistance of myoblasts to oxidative stress is mediated by SIRT1 by enhancing the activity mangan superoxide dismutase (MnSOD) \[[@B24]\], whereas overexpression of SIRT1 protein diminishes oxidative stress by activation of FoxO1-dependent pathway \[[@B25]\], latter resulting in reduced cardiac infarct volume and improved functional recovery after ischemia/reperfusion in mice \[[@B26]\].

The purpose of this study was to investigate the association between *SIRT1* single-nucleotide polymorphisms (rs7895833 A \> G in the promoter region, rs7069102 C \> G in intron 4, and rs2273773 C \> T in exon 5 silent mutation)


of tissue hypoxia during/after surgery \[[@B43]\].

In one study, SIRT 1 protected the aging heart from contractile dysfunction, mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific sirtuin 1 knockout mouse model \[[@B44]\]. These two results indicate that SIRT 1 acts as a protective protein in different cardiac pathologies, in terms of either counteracting oxidative stress or cardiac dysfunction, developing after myocardial infarction.

5. Conclusion {#sec5}
=============

In conclusion, carrying the CC or CG genotypes, additionally the wild-type C allele of the rs7069102 single-nucleotide polymorphism, was associated with an increased risk of premature myocardial infarction, latter affecting SIRT1 and endothelial nitric oxide synthase protein expressions, irrespective of the underlying *SIRT1* genotype.

5.1. Study Limitations {#sec5.1}
----------------------

The patient number has to be enhanced to determine a clear association between disease phenotype, outcome, and  22 (20.4)
  Localisation of MI (anterior/inferior/other) (%)   56 (51.9)/21 (19.4)/31 (28.7)
  IRA (LAD/Cx/RCA/others) (%)                        56 (51.9)/19 (17.6)/32 (29.6)/1 (0.9)
  SYNTAX score                                       13.6 ± 7.3
  Thrombus aspiration without stenting               3 (2.8)
  Elective or emergent CABG after MI


Crystallographically observed folded topology of an unsubstituted γ-aminobutyric acid incorporated in a model peptide: importance of a C--H···O interaction.
To validate the existing hypothesis put forward by Navarro et al., we performed single crystal X-ray diffraction structural analysis of a designed model peptide incorporating an unsubstituted achiral γ-aminobutyric acid: Boc-Pro-γ-Abu-OH (1) lacking C-terminal amide group. The analysis established existence of an overall unusual tightly folded topology stabilized by a conventional N(i)···H--N(i + 1) and an unconventional C(i)--H···O(i) type intramolecular hydrogen bonding interactions, encompassing a five-membered and a six-membered ring motifs, respectively. Moreover, in conjunction with Fourier transform infrared (FT-IR) absorption study in solid KBr, the results provided evidence that two conventional and one unconventional noncovalent intermolecular interaction stabilize a right-handed helical architecture generated via molecular self-assembly by translating thein blood follows a two compartment model. The alpha half-life (due to distribution and elimination) is 2.9 min. while the beta half-life (due to elimination only) is 23 min. There was no statistical difference (T-test) between these results and those of HPLC analyses using radiotracers. As an indication of the sensitivity of the technique, after one hour, the tris concentration in the blood is approximately 20 micromolar. The signal-to-noise ratio of the MS/MS signal at this time was greater than 10:1.


understood by all cultures and people is a pretty amazing thing," and their "symbols and the objects or ideas they represent are works of art worth celebrating." And, like Design.org, they also "get excited about things like scale, proportion, and shape... and are committed to design and quality" in everything they do.

Ward Andrews

Hi, I'm Ward Andrews. I started Design.org in 2009, you can read about why here. Thanks for participating in the Design.org Community. I also run an interactive agency called Drawbackwards. I love basketball, electronic music and creating experiences that improve daily life. You can follow me on Twitter @wardandrews.epithelial cells and membrane vesicles, are sodium dependent and that this Na.sup.+ -dependent transport system is regulated through a Na.sup.+ -dependent P.sub.i cotransporter. B. Ni, et al,, Proceedings of the National Academy of Sciences (U.S.A.), 91:5607-5611 (1994).
The present invention describes the cloning and characterization of a human brain Na.sup.+ -dependent P.sub.i cotransporter which is selectively expressed in discrete populations of neurons and glia. Fluorescent in situ hybridization (FISH) analysis demonstrates that this Na.sup.+ -dependent P.sub.i cotransporter is located in chromosome 19 (19q13.3) which has been linked to susceptible gene(s) for late onset Alzheimer's disease. M. Mullan and F. Crawford, Trends in Neurological Sciences, 16, 398-403 (1993). The characterization and treatment of physiological disorders ms hereby furthered.


hopes her work will yield results that will convince companies to adopt her process. “I cannot convince them unless I have some statistics and values and unless it is cost-effective,” Al Beloushi said.

The other three winners, who are all assistant professors at universities are Dr Maha Al Asmakh from Qatar University; Shimaa Hassan Eisa from the College of Science and General Studies in Riyadh; and Lila Habib from Kuwait University.

Nearly 2,250 women in over 110 countries have been recipients of the Fellowship over the past 18 years. With Unesco, the Foundation has honoured almost 100 award laureates for their research achievements — two of whom have gone on to win a Nobel Prize.

Thierry Houssin, managing director, L’Oréal Middle East, said the fellowship “continues to build on our firmGet your spandex and handcuffs out -- it's about to get real slippery in here.

There's been plenty of coverage about the morning-sex-inducing, bacon-flavored lube. But what about all the other greasy love products out there?

Today, a major rival will have its say in what could be the sexiest debate since Lincoln vs. Douglas in 1858. We're talking, of course, about Baconlube vs. Honey Lube.

Yes, the founders of each sexual condiment has decided to lube up and smack down to convince you, the reader, to take their product into the bedroom.

In one corner, there's Baconlube by J & D's Foods -- the result of an April Fool's joke gone viral. Co-founder Dave Lefkow said his product smells as wonderful as the morning waft of sizzling pork in the bedroom.

In


petition on his behalf. The IJ denied the request and entered an order of removal. Ramchandani timely appealed to the Board of Immigration Appeals ("BIA").

4
While the case was pending on appeal, Ramchandani filed a motion to reopen the removal proceedings. He attached an application to adjust status to his motion to reopen, which was based on an unapproved visa petition that his wife had filed subsequent to the IJ's order of removal. Ramchandani's motion admitted, and a marriage certificate he attached as evidence showed, that he had actually married O'Hanlon after the IJ's order of removal, on July 8, 2003. The BIA affirmed the IJ's denial of a continuance and denied Ramchandani's motion to reopen. Ramchandani appeals these two rulings.

II. Discussion

A. DENIAL OF CONTINUANCE

5
The BIA affirmed the IJ'sand ... was not entered into for the purpose of procuring the alien's admission as an immigrant...." 8 U.S.C. § 1255(e). We cannot conclude that Ramchandani's bare testimony that he married a U.S. citizen a few days before his hearing — unsupported by a visa petition, an adjustment application, or by any evidence indicating he had married in good faith — amounted to a showing of good cause so as to warrant a continuance.

B. DENIAL OF MOTION TO REOPEN

14
Lastly, Ramchandani argues that the BIA erred in denying his motion to reopen. We review the denial of a motion to reopen "under a highly deferential abuse-of-discretion standard." Zhao v. Gonzales, 404 F.3d 295, 304 (5th Cir.2005).6

15
Ramchandani sought reopening to apply for adjustment of status through a concurrently filed visa


n. 26 (5th Cir.1999).

2
 Even if Ramchandani had produced evidence that an application for labor certification was timely filed, it is far from clear that the denial of a continuance would have been an abuse of discretion. InZafar v. U.S. Attorney General, the Eleventh Circuit held that the denial of a continuance to await decisions on aliens' pending labor certificate applications was not an abuse of discretion. 426 F.3d 1330, 1335 (11th Cir.2005). The "speculative possibility that at some point in the future they may receive ... labor certification" was not sufficient for a showing of good cause. Id. (internal quotation marks omitted, emphasis in original).

3
 The BIA affirmed the IJ's denial of a continuance on abuse of discretion, rather thande novo, review. We assume without deciding thatwere some interesting cars out of his Havertown,PA shop.

If you go to the FB site there are pics of the cars Dick has raced; hotrod Fords, Healey/Chev, Ferrari, Lister, F5000, Cobra, and TR4 besides the alloy Mk.IV.
In the '70s he had an IMSA sedan that also got wrinkled. Dick is still involved with the Kyle Disque GTL Toyota effort.


T4216C mutation in NADH dehydrogenase I gene is associated with recurrent pregnancy loss.
Several genetic factors are involved with recurrent pregnancy loss (RPL). However, few attempts have been made to associate mitochondrial DNA (mtDNA) variations with RPL. Therefore, we investigated the possible effect of the T4216C mutation in the mitochondrial NADH dehydrogenase I (ND1) gene of 33 women with RPL and 100 controls, using polymerase chain reaction amplification and DNA sequence analysis. Our results showed a statistically significant association of the T4216C mutation (p < 0.05) between patients and controls, which are 30% and 11%, respectively. In conclusion, more research is essentially needed to understand the effect and role of the T4216C mutation in the progress of RPL, which may vary among individuals and different ethnic groups.Q:

Data migration from MongoDB to Teradata

We are working towards migrating data from MongoDB to Teradata (DW).
We feel that transformations on the data will be necessary.
Could you please help me answer the below questions which will guide us on developing a solution for migration :

Which would be the best and efficient format to export data from MongoDB to load into Teradata(DW) considering transformations involved ? (CSV/JSON/Others)

Transformations could include omission of line(s) from the exported file, omission of fields, aggregation(sum/count) across fields etc.

If developing a framework for ETL, will Java be a good choice ?
We noticed that ‘\n’ [newline character] is also part of some records. Hence, in the csv we are seeing some blank lines in between.

Do we need to be concerned of the right line delimiter ? Or


this question. And thank you for hanging out and listening to the show today. If you liked it, please leave me a review in iTunes. Your review will help others find this podcast and it will let me know that you like what you heard.

For more information and inspiration on getting and growing your job making video games, visit me at gameindustrycareerguide.com. I am Jason W. Bay and I’ll see you next time, right here on the Game Industry Career Guide podcast.book examines American democracy from the vantage point(s) of those who are living in or near poverty, (disproportionately) Black or Latino, and reliant on a federated government for vital resources.

Investigates how Medicaid affects political participation and democratic citizenship

Shows how federalism works in everyday life - as it intersects with poverty and race - to clarify the stakes of policy choices

Sheds light on previously unconsidered mechanisms of political inequality

Puts the voices and experiences of Medicaid beneficiaries front and center

Reviews & endorsements

‘I have not read a book in a better part of a decade where I learned as much or where my ideas of American federalism were so usefully challenged. With incredibly keen insight and breathtaking analysis, Jamila Michener unearths the dire ramifications of how people-based policies intersect with place-based


cells either by direct injection into the "naked" ECM or transfusion through spared vascular channels \[[@CR39]\]. The latter approach appears better suited to reestablish a homogenous musculature in the heart but would require that cells migrate into the heart's ECM and form a continuous functional syncytium. Future studies will have to provide evidence that this can indeed be achieved and that the resulting hearts can be transplanted and perform as desired in vivo. To this end, first short-term data from a heterotopic heart transplantation model are encouraging \[[@CR39]\].

Limitations {#Sec3}
===========

Myocardial tissue engineering still has to go a long way in order to be translated into a clinically exploitable treatment modality, and it is difficult to predict when or even whether it will ever reach its proposed potential. Yet, importantare not readily available. Adult stem cells from the blood or bone marrow would be logistically ideal but do not have the intrinsic capacity to give rise to cardiomyocytes of sufficient quality and quantity \[[@CR2]\]. In contrast, embryonic stem cells can give rise to *bona fide* cardiomyocytes \[[@CR8], [@CR20], [@CR54]\], which would, however, elicit an immune response in an allogenic recipient \[[@CR25]\]. Alternatively, induced pluripotent \[[@CR49]\], spermatogonial \[[@CR16]\], and parthenogenetic \[[@CR51]\] stem cells could be applied autologously. These cell types appear to have the most characteristics of embryonic stem cells, including the capacity to give rise to cardiomyocytes. This makes them an attractive source for cardiac-muscle-engineering and other tissue-engineering applications. Finally, the necessity for an autologous application needs to be carefully considered, given the time needed to generate


catch(PDOException $e)
 {
      echo "Connection failed: " . $e->getMessage();
 }

 if (isset($_POST['Name']) && isset($_POST['Email']) &&
 isset($_POST['Password'])){
//Insert new contact into database
$query = $conn->prepare('INSERT INTO contact_info (contact_name,
contact_email, contact_password) VALUES (:name, :email, :password)');
$query->execute([
    ':name' => $_POST['Name'],
    ':email' => $_POST['Email'],
    ':password' => $_POST['Password']
]);
echo"done";
}
?>

The connection to the database is working fine as I get "connected succesfully" but nothing is added to the database. I don't know where the problem is coming from.
Hope you can help,
Thanks for your help.
EDIT:
I'm now using Ravi's code:` String urlParameters  = "Name="+name+"&Email="+email+"&Password"+password;
        byte[] postData       = urlParameters.getBytes( StandardCharsets.UTF_8 );
                                                                                at com.android.internal.os.ZygoteInit.main(ZygoteInit.java:1408)

I am really stuck,, pleasse hellpp...

A:

If var_dump($POST) prints null, which means, you have issue when your request is getting constructed.
Also, I noticed, you haven't specify the request type in your code. So, probably just specify
conn.setRequestMethod( "POST" );

If still doesn't work, Then, use below


Q:

How to update a record directly referenced in VF Page?

I'm using Custom Object and displaying the fields to be editable on the vf page. Can I update it directly on Controller class? My code is provided below:
Apex Class:
public class MyController{
     public Object items{get;set;}
     public void getValues(){
        items = [Select Id, Name, Data1 from Object where Id=:ApexPages.currentpage().getparameters().get('Id')];
     }
     public void updateValues(){
        //Do I need to query the object again???
        items = [Select Id, Name, Data1 from Object where Id=:ApexPages.currentpage().getparameters().get('Id')];
        update items;
    page at https://www.facebook.com/pinkdollarinc or follow them on Twitter@pinkdollarinc to stay tuned for their latest news and the launch date. There will be a launch party, and if you ‘like’ their Facebook Page, you’ll be on the invitation list!I think we all just want to enjoy our lives without any hassle for being what we are, so if what Pink Dollar promises is true, we at least won’t have to worry about where to go to shop. We may not need an application to provide us a safe zone, but the world, even in Hong Kong, can be very ignorant in the way it acts towards gay people, and we shall soon have Pink Dollar to help us find a comfortable way around in it.Article from Fridae


inability to use, or results of the use of our site, any websites linked to it and any materials posted on it, including, without limitation any liability for:

7.2.1loss of income or revenue; 7.2.2 loss of business; 7.2.3 loss of profits or contracts; 7.2.4 loss of anticipated savings; 7.2.5 loss of data; 7.2.6 loss of goodwill; 7.2.7 wasted management or office time; and 7.2.8 for any other loss or damage of any kind, however arising and whether caused by tort (including negligence), breach of contract or otherwise, even if foreseeable, provided that this condition shall not prevent claims for loss of or damage to your tangible property or any other claims for direct financial loss that are not excluded by any of the categories set out above.

7.3This does notthe study directed interested members to the study\'s website, where additional information was available. The study\'s ICF was also accessible on the website, where it could be signed electronically. Upon signing the ICF, members were randomly assigned to receive the ECG patch either immediately (immediate monitoring group) or 4 months later (delayed monitoring group).

2.4. Email recruitment {#sec2.4}
----------------------

The email recruitment process was designed to be iterative ([Fig. 1](#fig1){ref-type="fig"}). Each week, batches of 2000--10,000 invitations were sent and the response rates measured (percent of emails received, opened, and clicked through, and participants enrolled). The findings were then used to inform each subsequent version of the invitations. The first invitations for participation were sent in November and December 2015, as two email batches targeting a total of 2500 members. All emails


email bodies in these tests used the same subject line, contained the same introductory paragraph describing the study, displayed one of the three specific appeals in bold, included the same single, large call-to-action button ("Learn More"), and included disclosure statements at the bottom (see [Supplementary Material](#appsec1){ref-type="sec"}). The control email body was the original email invitation that included references to all three appeals and had no call-to-action button.

A final, multiple-reminder email campaign was launched in the last month of recruitment targeting 26,000 eligible members who had not enrolled in response to previous original or reminder emails. The campaign involved three emails, each with a different appeal, sent two weeks apart.

Data tracked and collected by Aetna for each batch of emails included the number of emails sent (i.e., the numberthe same language as the original email body, instructions to type in the website address or to use a search engine to find the link, and the study telephone number (see [Supplementary Material](#appsec1){ref-type="sec"}). Data to assess the effectiveness of the regular mail campaign were limited to the number enrolled.

2.7. Optimized campaign {#sec2.7}
-----------------------

Following the email and regular-mail campaigns, another 8053 members were targeted in a multifaceted campaign conducted over 3 weeks, including three emails sent 1 week apart and two redesigned mailers sent at the beginning and end of the campaign. Content was based on the best-performing subject lines and email bodies identified in the previous campaigns, which included personalization and an emphasis on the technology, with images consistent with the study website (see [Supplementary Material](#appsec1){ref-type="sec"}). Effectiveness of the


patient-reported understanding \[[@bib10]\]. And in a recent worldwide online survey (*N* = 12,427), 60% of respondents reported the use of some form of technology in their clinical studies, most commonly taking the form of text messaging (18%), use of a tablet for informed consent (17%), use of a smartphone app (10%), and use of wearable devices (8%) \[[@bib11]\]. Given that 23% of the respondents in this survey also listed "location of the study" as one of the least-liked aspects of research participation, the use of remote technologies can offer convenience and flexibility to an expanding pool of candidate subjects.

Our findings from the mSToPS study show the feasibility of remote clinical-trial recruitment. In addition, an iterative, dynamic approach to recruitment that isolates individual motivators can help researchers understand which aspects ofor suppression of several cellular signalling pathways that determine the subsequent cellular fate. Accidental MeHg poisonings involving humans have been recorded, including in Japan[@b7], Iraq[@b8], and the USA[@b9]. MeHg toxicity currently continues to be an environmental risk to human health, especially in susceptible populations who frequently eat substantial amounts of fish or fish predators. The critical role of oxidative stress in the pathogenesis of MeHg toxicity has been demonstrated both *in vitro*[@b10][@b11][@b12][@b13][@b14][@b15][@b16] and *in vivo*[@b17][@b18][@b19]. Failure to protect cells against MeHg-induced early oxidative stress triggers subsequent ER stress and apoptosis, suggesting that protective factors against ER stress may be important in combating MeHg cytotoxicity, especially in its later stages[@b14]. Furthermore it has been reported that the overexpression of the ubiquitin-conjugating enzyme cdc34 protects cells against MeHg cytotoxicity[@b20][@b21], suggesting


pathway. The upregulation of Atf4 protein by ER stress preconditioning appears to be mainly mediated by phospho-Eif2α-induced facilitation of the bypass of inhibitory uORF. The induction of ISR led to the upregulation of Grp78, which is critical to protect cells against MeHg cytotoxicity. The results indicate that ER stress plays an important role in MeHg cytotoxicity and that the modulation of ER stress has therapeutic potential to attenuate MeHg-induced cell injury. Atf4 and Grp78 are the major targets in ER stress-induced protection against MeHg toxicity.

Methods
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Chemicals and reagents
----------------------

We purchased TPG, Trolox, and dithiothreitol (DTT) from Sigma-Aldrich, a Cell Counting Kit from DOJINDO, nitrocellulose membranes from Bio-Rad, SAPK/JNK and p44/42 MAPK Assay Kits from Cell Signaling Technology, a SYBR Green Master Mix from Roche, Lipofectamine RNAiMAX and 5-(and 6-)chloromethyl-2′,7′-dichlorodihydrofluorescin diacetate,is that the guarantees are going to be reviewed and the Cabinet has the next two weeks to go through them.

“Remember, the government had given support for the 2015 tournament and what is left now is for government to qualify what those guarantees mean,” said Mbebe.

He said hosting the event would cost each host city about R22 million and also acknowledged receipt of a letter from the Mangaung Municipality raising concerns about the HCA.

The Polokwane Municipality said the HCA terms were not favourable to them and they were not happy with centralised procurement. Community Development Director Ndavhe Ramakuela said they had not signed the HCA.

Grant Pascoe of the City of Cape Town said they too had not signed the agreement. He said they were still engaged in talks


with their technical team and the LOC.

He said they estimated about R27 million to host a number of games but “there are some other costs that the city will have to cover”.

CAF vice-president Suketu Patel said the organisation – which has cellular network company Orange, Standard Bank, Pepsi and Adidas as sponsors for the event as well as French company Sports Five as a broadcast partner – will commit $6 or $7 million (about R50 million) to the host federation.

CAF is also responsible for prize money of about R76 million.

“This might not be enough, hence the host country must meet certain requirements and guarantees. CAF asks for federations to bid and those that bid know what is expected,” he said.

While the HCA states that “cities are encouraged to   self.assertEqual(("D" + str(i)).encode(), sess.run(get_next))
                # Save current offset which is 2
                saver.save(sess, model_file, global_step=3)

            checkpoint_file = "/tmp/test-kafka-model-3"
            with self.cached_session() as sess:
                saver.restore(sess, checkpoint_file)
                # Restore current offset to 2