would include "residential units, hostels, prisons, pubs, clubs, festivals and venues essential to the social and night-time economies".

The litany of concerns also slams the government for removing references to the harm caused by a drug - as opposed to its psychoactivity - from drug law. It means that suppliers of benign substances could be prosecuted, the council argues.

Legal highs like these would be banned if the government's Psychoactive Substances Bill comes into effect (Christopher Furlong/Getty Images)

Scientific and medical research would be impeded the bill will "criminalise and apply disproportionate penalties to many otherwise law abiding young people and adults", especially ethnic minorities. So-called high-street "headshops", currently selling legal highs would close, driving customers towards "illegal dealing networks", the letter adds.

The letter calls for Mrs May to redraft thebounded maximum degree. The algorithm is given query access to the adjacency list to such a graph. We then formalize the notion of *robust clustering oracle* for a noisy clusterable graph, and give an algorithm that builds such an oracle in sublinear time, which can be further used to support typical queries (e.g., IsOutlier($s$), SameCluster($s,t$)) regarding the cluster structure of the graph in sublinear time. All the answers are consistent with a partition of $G$ in which all but a small fraction of vertices belong to some good cluster. We also give a *local reconstructor* for a noisy clusterable graph that provides query access to a reconstructed graph that is guaranteed to be clusterable in sublinear time. All the query answers are consistent with a clusterable


be large and $\phi_{{\textrm{out}}}$ to be small. In particular, if $S=V$ and $\phi(G[V])=\phi(G)\geq \phi_{\textrm{in}}\geq \phi$ for some constant $\phi$, then we call the graph $G$ a *$\phi$-expander* which by itself is a good cluster and has been extensively studied in theoretical computer science (see e.g., [@HLW06:expander]). It is useful to note that $\phi_G(V)=0$. When $G$ is clear from the context, we omit the subscript $G$ from $\phi_G(S)$. A *$k$-partition* of a graph $G=(V,E)$ is a partition of $V$ into $k$ subsets, $V_1,\cdots, V_k$ such that $V_i\cap V_j=\emptyset$ for $i\ne j$ and $\cup_i V_i=V$. We have the following definition of clusterable graphs that characterize graphs with typical cluster structure (see e.g., [@OT14:partitioning]).

Given parameters $d, k,\phi_{\textrm{in}},\phi_{\textrm{out}}$, we call a $k$-partition $P_1,\cdots,P_k$ of a $d$-bounded graph $G$ a *$(k,\phi_{\textrm{in}},\phi_{\textrm{out}})$-clustering* if for each $i\leqbe partitioned into at most $k$ parts, each with relatively large inner conductance (i.e., $\Omega_k(\frac{\varepsilon\phi}{\log n})$), with no guarantee on outer conductance (as each set trivially has outer conductance at most $1$). (Such instances are exactly the object that was studied in [@CKKMP18:cluster] in the framework of property testing.) By sacrificing the inner conductance quality, we can also find a clustering of $G'$ with small outer conductance. That is, we can guarantee that $G'$ is also $(k,\Omega(\frac{\nu^k}{6^kk^4}\frac{\varepsilon\phi}{\log n}),\min\{k\nu, 1\})$-clusterable for any $\nu\in[0,1]$ (see Appendix \[sec:cluster\_outersmall\] for details). Item \[item:consistent\] implies that all query answers are consistent, that is, the vertex $u$ is output as a neighbor of $v$ in $G'$ if and only if $v$ is output as a neighbor of $u$. From the discussion below on the connections between our


(between $G_{\exp}$ and $G$) and has been used to repair expander graphs in [@KPS13:noise]. Then the answers is guaranteed to be consistent with a graph $G'$ such that its distance to the original graph $G$ is at most $d$ times the number of vertices that are reported as outliers, which has already been bounded to be small. In order to prove the claimed guarantee on cluster structure of $G'$, we introduce a definition of *weak* vertices that intuitively correspond to the noisy part of the graph. Such a definition has also been used in [@KPS13:noise], though ours is more subtle, depending on the size of noise. We can show that one can improve the cluster structure of the graph if we have repaired all the weak vertices in the\frac{\phi}{2} d\cdot \frac{1}{3}|B_i|=\frac{\phi}{6}d|B_i|$ edges, where the inequality follows from the fact that $|C_i-B_i|\geq \frac{1}{3}|B_i|$ which in turn is due to the fact that $|B_i|\leq \frac{3}{4}|C_i|$. Therefore, in order to make all $C_i$ have inner conductance at least $\phi$, we have to add at least $\sum_i \frac{\phi}{6}d|B_i|>\frac{\phi}{6}d\cdot \frac{6\varepsilon}{\phi} n=\varepsilon d n$ edges, which is a contradiction.

We note that since $\varepsilon\leq \frac{\phi}{60k^2}$, then it holds that at least one $D_i$ has size at least $\frac{(1-(6\varepsilon/\phi))n}{k} \geq \frac{9n}{10k}\geq 3\sqrt{\frac{1}{10k^2}}n\geq 3\sqrt{\frac{6\varepsilon}{\phi}}n=3\sqrt{\varepsilon'} n$. Now we apply Theorem \[thm:rw\_perturbed\] on $G$ with error parameter $\varepsilon'=\frac{6\varepsilon}{\phi}<\frac{{\ensuremath{\kappa}}^2}{100}$, ${\ensuremath{\gamma}}= \frac{{\ensuremath{\kappa}}}{2}$, sets $C_i=D_i\cup B_i$, $1\leq i\leq \overline{h}$ such that $\phi(G[D_i])\geq \frac{\phi}{2}$, to obtain that for each $D_i$ with $|D_i|\geq 3\sqrt{\varepsilon'}n$, there exists a subset $\widehat{D}_i\subseteq D_i$ such that $|\widehat{D}_i|\geq (1-4\sqrt{\varepsilon'})|D_i|$ and for any $v\in \widehat{D}_i$, and $t= \frac{960\log n}{{\ensuremath{\kappa}}\phi^2}$,


that for any $C_j$ with $j\neq i$, there can be at most $\kappa |C_j|$ vertices $u\in C_j$ with ${\ensuremath{\mathrm{rcp}}}_{\theta_0}(u,v)>\frac{1-5\sqrt{\kappa}}{|C_j|}$, this is true since the total probability mass on $C_j$ of the random walk distribution from $v$ is at most $\kappa$. This ensures that there will be a unique core corresponding to $v$. Let $\sigma:[h']\rightarrow[h']$ denote the corresponding bijection between $\{C_1,\cdots,C_{h'}\}$ and the cores $\{S_1,\cdots, S_{h'}\}$ found by the algorithm. By union bound, we have that with probability at least $1-\frac{1}{n}$, for each strong vertex $v\in S_i'$, the algorithm will answer the corresponding index $\sigma(i)$ to the query WhichCluster($v$).

#### Running time and query complexity.

Note that in the learning phase, we need to invoke the procedure EstimateRCP for $|S|\times |S|=O(\frac{k^4\ln^2 k \cdot \phi\log^2n}{\varepsilon})$ times, and each invocation takesthen add all the $G_{\exp}$-edges $(w,u)$ incident to $w$;

Otherwise, for each vertex $u$ that is a $G_{\exp}$-neighbor of $w$, run CheckCore($H,u$). If $u$ is reported as **Outlier**, then add edge $(w,x)$.

Output all neighbors added to $w$ and all $G$-neighbors of $w$.

\

Note that the algorithm should be implemented by first taking as input a random seed $s$, which is fixed once for all (and used for sampling vertices in the learning phase and performing random walks), and then on any query vertex $v$, *deterministically* outputting the neighborhood of $v$ in the graph $G'$. By construction, if an edge $(u,v)$ is added, then on query vertex $u$, $v$ will be output as a neighbor of $u$ and vice versa. Therefore, the algorithm is independent of the order of queries


case that $\varepsilon \in [\Omega(\frac{\phi}{{n}}),   \frac{\phi\kappa^2}{100}]$. In this case, the description of the local reconstruction algorithm, the number of added edges is $16$ times the number of vertices that are reported as outliers, and thus by Lemma \[lemma:reported\_outliers\], is at most $16\times 40k\sqrt{\frac{\varepsilon}{\phi}}n = 640k\sqrt{\frac{\varepsilon}{\phi}}n$. Now we analyze the cluster structure of the resulting graph.

#### Definition and property of weak vertices.

Let $\varepsilon':=\frac{6\varepsilon}{\phi}<\frac{{\ensuremath{\kappa}}^2}{100}$. We introduce the following definitions of weak vertex for the analysis, which was inspired by the corresponding definitions for noisy expander graphs in [@KPS13:noise]. The main difference here is that we carefully take the size of clusters into consideration.

We call a vertex $v$ *weak* vertex, if for any subset $A$ with $|A|\geq \frac{2\varepsilon'}{3} n$, it holds that ${\lVert{\textbf{b}}_v^{t}-{\ensuremath{\mathbf{\mathcal{U}}}}_{A}\rVert}_{{\textrm{TV}}} \geq 1/4.$

In order to analyze the cluster structure\frac{\rho(h)}{\lambda_{h+1}}.$

Note that by definition, $\rho(h)\leq \phi_{\textrm{out}}$. In addition, by Lemma \[lemma:spectral\_clusterable\], it holds that $\lambda_{h+1}\geq \frac{\phi_{\textrm{in}}^2}{2}$. Furthermore, since $\phi_{\textrm{out}}\leq a_{\ref{thm:PSZ_structure}}\phi_{\textrm{in}}^2/k^2\leq a_{\ref{thm:PSZ_structure}}\phi_{\textrm{in}}^2/{h^2}$, it holds that $\lambda_{h+1}/\rho(h)\geq \frac{\phi_{\textrm{in}}^2}{2\phi_{\textrm{out}}}=ch^2$ as $a_{\ref{thm:PSZ_structure}}$ is sufficiently small constant. This then implies that ${\lVert{\ensuremath\mathbfv}_i-\tilde{{\ensuremath\mathbfr}}_i\rVert}_2^2\leq 1.1 h\cdot \frac{\rho(h)}{\lambda_{h+1}}\leq c_{\ref{thm:PSZ_structure}}\cdot \frac{h\phi_{\textrm{out}}}{\phi_{\textrm{in}}^2}$ for some constant $c_{\ref{thm:PSZ_structure}}$.

Now we are ready to prove Theorem \[thm:rw\_clusterable\]. We first provide a high level idea. We will bound the $\ell_2$-norm distance of the random walk distribution ${\textbf{p}}_v^t$ and the uniform distribution ${\ensuremath{\mathbf{\mathcal{U}}}}_C$ over the cluster $C$ that contains $v$, i.e., ${\lVert{\textbf{p}}_v^t-{\ensuremath{\mathbf{\mathcal{U}}}}_C\rVert}_2$. In order to do so, we note that by Theorem \[thm:PSZ\_structure\], the vector ${\ensuremath{\mathbf{\mathcal{U}}}}_C$, which is a scale of the indicator vector of $C$, lies in a space that can be well approximated by the space of the first $h$ (where $h\leq k$ is the


$|\widehat{D}_j|\geq (1-3\sqrt{\varepsilon})|D_j|-3\varepsilon n \geq (1-4\sqrt{\varepsilon})|D_j|$. Thus, for any $s\in \widehat{D}_j$, both inequalities (\[eqn:gamma\]) and (\[eqn:mixing\]) hold.

Now let us consider an arbitrary $s\in \widehat{D}_j$. Let $\tau=\tau_s$ and $\sigma={\textbf{1}}_s$. By the precondition of the Theorem, we have that $t=\frac{120\log n}{{\ensuremath{\gamma}}\phi_{\textrm{in}}^2}=\frac{6\ell}{{\ensuremath{\gamma}}}$. We further recall that ${{\textbf{a}}}_s^t$ denotes the distribution of a uniform average walk of length $t$ with initial distribution $\sigma$ in the original chain ${\ensuremath{\mathcal{M}}}$. By applying Lemma \[lemma:averagewalk\] with $\sigma^{(t)}={{\textbf{a}}}_s^t$ and distribution $\tau$, we obtain that for any $U\subset V$, $$\begin{aligned}
        \sum_{i\in U}{{\textbf{a}}}_s^t(i) \leq \frac{1}{t}{\ensuremath{\mathcal{H}}}(\sigma,\tau) + \frac{1}{t}\sum_{i\in U}\sum_{m=0}^{t-1}\tau^m(i),
    \end{aligned}$$ where $\tau^m$ denotes the distribution of an $m$ step random walk on $G$ with initial distribution $\tau$, that is $\tau^m=\tau{\ensuremath\mathbfP}^m$. (Here we slightly abuse the notation $\tau$ and use it to denote the    \end{aligned}$$ This finishes the proof of the Claim.

This finishes the proof of Theorem \[thm:rw\_perturbed\].

Conclusions {#sec:conclusions}
===========

We gave the first robust clustering oracle and local filter for reconstructing the cluster structure of bounded degree graphs. Both algorithms run in sublinear times. To design and analyze our algorithms, we formalized and proved a new behavior of random walks in a noisy clusterable graph: a random walk of appropriately chosen length from a typical vertex in a large cluster of the clusterable part will mix well in the corresponding cluster, which might be of independent interest.

It will be an interesting open question to design a local reconstruction algorithm that outputs a clusterable graph with better cluster-quality guarantee, especially to remove the $\Theta(\log n)$ gap between the inner conductances of


do not have web feet?

I mis typed, sorry. webbed toes on the paws. Orginial Basenjis taken to England in the 1930's were said to have connected toe pads. I refered to them as webbed, but I understand that it not acturate. Sorry Again

As an Italian and salami eater....all my dogs feet smelt like salami even my new basenji pup Duna. And i dont mean the salami slices,,,but the whole thing on the outside!!!!
But i love the smell ( stink) ha-ha!!!

I totally noticed that paw thing the day we rescued Starla!! As for corn chips ...
Can anyone tell me if Basenjis can "spray," though? We've noticed that if Starla is doing something naughty or if she's nervous, she makes a skunky smell. ... I googled it and didn't pull280,000 (HA280K group), 500,000 (HA500K group), and 4,000,000 (HA4M group) molecular wt] or with a different concentrations of hyaluronan [(molecular wt 500,000); 0.01% (0.01% HA group), 0.05% (0.05% HA group), 0.1% (0.1% HA group), and 0.5% (0.5% HA group) hyaluronan]. The peritoneal fluid absorption rate (as assessed by the RISA elimination rate, KE) was significantly decreased in the HA500K and H4M groups as well as in all the different concentration groups (with molecular wt 500,000) as compared with the control group, resulting in significantly higher net fluid removal in these groups (except for the H4M group) as compared with the control group. In the 0.5% HA group (but not in the other hyaluronan groups), the direct lymphatic absorption (KEB) was also significantly decreased. The transcapillary ultrafiltration rate (Qu)


the overall lower FRs of neurons in rats with chronic pain compared with naive rats, indicates a deficit in the nociceptive response at the level of individual prefrontal neurons.

Previous *in vitro* findings suggest the decreased excitability of neurons in the PFC in chronic pain models ([@R11]; [@R15]; [@R28]; [@R39]). This hypoexcitability, however, has not been observed in free-moving animals. This hypoexcitability should manifest as decreased basal spontaneous FRs in our study. As expected, we found that chronic pain indeed decreased the spontaneous FRs of all of the recorded neurons ([Figure 2G](#F2){ref-type="fig"}), including neurons that specifically responded to acute pain ([Figure S2B](#SD1){ref-type="supplementary-material"}).

The PFC Can Function as a Cortical Gain Control Center for Pain {#S5}
---------------------------------------------------------------

Next, we analyzed the relation between basal and pain-evoked FRs in these prefrontal neurons. It isthe chamber associated with a painful stimulus, if that stimulus was coupled with enhanced prefrontal outputs ([Figures 4Q--4S](#F4){ref-type="fig"}). Taken together, these results suggest that low-frequency stimulation, by restoring basal activities, can scale up prefrontal control to relieve the aversive quality of chronic pain. We did not observe any rewarding effect of low-frequency stimulation in the absence of noxious stimulation, nor did prefrontal stimulation alter locomotion ([Figure S4](#SD1){ref-type="supplementary-material"}), suggesting that enhancing basal prefrontal activities did not significantly alter baseline sensory and motor behaviors.

To further verify the specificity of this gain control mechanism for pain in prefrontal neurons, we inactivated the outputs from PL-PFC in naive rats by expressing halorhodopsin in their pyramidal neurons ([Figure 5A](#F5){ref-type="fig"}). We then performed Hargreaves and CPA tests in the presence of PFC inactivation. We


the same or different PFC neurons may exhibit different spiking patterns and project to other brain regions to drive different sets of behaviors. When the optogenetic activation was coupled with a pain stimulus in our study, it was able to activate further those pain-responsive neurons to inhibit pain. Conversely, inhibition of these PFC neurons resulted in a lack of endogenous regulation and subsequently increased pain. Hence, our results provide a crucial physiological basis for previous data showing the ability of PFC stimulation to inhibit pain ([@R10]; [@R17]; [@R20]; [@R23]; [@R39]). In addition, our results demonstrate for the first time that chronic pain suppresses the prefrontal response to nociceptive inputs at the population level and the level of individual neurons.

The concept of gain control for nociceptive processing has beenwith controlled humidity, temperature, and 12-hr (6:30 AM--6:30 PM) light-dark cycle. Food and water were available ad libitum. Animals arrived at the animal facility weighing 250 to 300 g and were given on average 10 days to adjust to the new environment before the initiation of experiments.

CFA Administration {#S11}
------------------

To induce chronic inflammatory pain, 0.1 mL of CFA (*Mycobacterium tuberculosis*, Sigma-Aldrich) was suspended in an oil:saline (1:1) emulsion and injected subcutaneously into the plantar aspect of the hind paw opposite to the paw that was stimulated by PP. CFA always was administered into the paw that was ipsilateral to the recording electrodes. Control rats received an equal volume of saline injection.

Virus Construction and Packaging {#S12}
--------------------------------

Recombinant adeno-associated virus (AAV) vectors were serotyped with AAV1 coat proteins and packaged at the


secured to the skull screws with dental cement.

After animal sacrifice, brain sections (20 μm) were collected using a Microm HM525 cryostat machine (Thermo Fisher Scientific) and analyzed for viral expression and optic fiber localization with histological staining. Animals with improper fiber or electrode placements, low viral expression, or viral expression outside the PL-PFC were excluded from further analysis.

Chronic Optrode Implant and Intracranial Injections {#S15}
---------------------------------------------------

Tetrodes were constructed from four twisted 12.7 μm polyimide-coated microwires (Sandvik) and mounted in an eight-tetrode VersaDrive Optical (NeuraLynx). A 200 μm optic fiber held in 1.25 mm ferrules (Thorlabs) were mounted in the VersaDrive Optical such that the fiber was 0.5--1 mm above the mounted tetrodes. Electrode tips were plated with gold to reduce electrode impedances to 100--500 kΩ at 1 kHz. Rats werebefore stimulus onset and the peak pain-evoked firing rate to be the maximum value of the PSTH after stimulus onset (within 5 s from the stimulus). We also used a linear regression model to fit the baseline mean FRs versus the peak pain-evoked FRs.

To define a neuron that altered its firing rate in response to a peripheral stimulus, we used the method described by [@R40]. The baseline mean is the average of the PSTH bins before stimulus onset, and the standard deviation is the standard deviation of the PSTH bins before stimulus onset. To calculate the *Z* scored firing rate, we used the following equation: *Z* = (*FR* − mean of *FR~b~*)/standard deviation of *FR~b~*, where *FR* indicates the firing rate for each bin and *FR~b~* indicates the


Alcohol laws in Eagleton Village, Tennessee

This page contains information specific to Eagleton Village regarding whether liquor may be sold for on-premises consumption, but otherwise reflects the default hours of sale in Tennessee. The laws in effect in Eagleton Village may differ from what is shown here.

Hours of sale for liquor stores, gas stations, and supermarkets:

AM

PM

AM

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8

9

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12

1

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3

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5

6

7

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9

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Monday

Tuesday

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alcohol sales permitted

beer and wine

alcohol sales not permitted

In Eagleton Village, a census designated place in Blount County, Tennessee, the sale of packaged liquor is prohibited on Sunday. Packaged liquor may be sold between 8:00 a.m. and 11:00 p.m., Monday through Saturday (subject to variation by local ordinance).

The sale of packaged beer and wine is prohibited on Sunday. Packaged beer and wine may be sold between 6:00 a.m. and midnight, Monday through Saturday (subject towith enlargement of the A2 pulley and adjacent proximal sheath by incision and repair with an extensor retinacular graft. Results were analyzed statistically. Gliding resistance increased from an average of 0.44 N +/- 0.07 in the intact condition to an average of 1.51 N +/- 0.23 (a mean increase of 243%) when the tendons were cut and repaired. Enlarging the proximal sheath by sheath incision and graft repair reduced the gliding resistance from the repair condition to 1.04 N +/- 0.15 (a mean decrease of 31%). These changes are statistically significant. In vitro, repaired tendons had a greater resistance to gliding than that of the intact tendons through the proximal sheath when tested by the method of Uchiyama and colleagues. Enlargement and repair with an extensor retinacular graft


during the revascularization procedure.
Accordingly, a need exists for apparatus and a method of use to revascularize partially or totally occluded blood vessels, while positively assuring that any particles produced during the revascularization procedure are removed from the patient's body. In the case of partially or totally occluded coronary bypass grafts, a need exists for intravascular atherectomy apparatus and methods of use for effectively producing a lumen through the occlusion for the free flow of blood, without the risk that any debris produced during the lumen opening procedure will enter into the aorta or downstream of the occlusion once it has been crossed or opened.are we saying that WinDAM B by USDA is not a good application for your computer. This text only contains detailed info on how to remove WinDAM B supposing you decide this is what you want to do. The information above contains registry and disk entries that Advanced Uninstaller PRO discovered and classified as "leftovers" on other users' computers.


It's not just the iPhone that's beingcloned: now this black 8GB Nokia N95 clone has joined the party. With dual slider keypads, a two megapixel camera with flash, another small camera, media player, Bluetooth and microSD card slot, it's actually not all that bad. It doesn't have the 8GB, of course. But you've got to admire the brazen advertising: "STRAIGHT FROM THE CLONING GODS OF CHINA! WE BRING YOU THE ALL NEW N95 DUAL SLIDE VERSION!" It gets worse.

"A CLONE THAT IS TRULY WORTHY TO BE CALLED AN EXACT REPLICA! SAME DIMENSION, MARKINGS, FEEL .... OVER ALL CLOSEST TO THE REAL N95 BLACK 8 GIG."

Looks like a very professional piece of tech-copying, doesn't it? Detailed right down to the Nokia logo splashed on the front. Those naughty ChinesePoro-viscoelastic behavior of gelatin hydrogels under compression-implications for bioelasticity imaging.
Ultrasonic elasticity imaging enables visualization of soft tissue deformation for medical diagnosis. Our aim is to understand the role of flow-dependent and flow-independent viscoelastic mechanisms in the response of biphasic polymeric media, including biological tissues and hydrogels, to low-frequency forces. Combining the results of confined and unconfined compression experiments on gelatin hydrogels with finite element analysis (FEA) simulations of the experiments, we explore the role of polymer structure, loading, and boundary conditions in generating contrast for viscoelastic features. Feature estimation is based on comparisons between the biphasic poro-elastic and biphasic poro-viscoelastic (BPVE) material models, where the latter adds the viscoelastic response of the solid polymer matrix. The approach is to develop a consistent FEA material model (BPVE) from confined


/*
 * Copyright (c) 2000-2004 Anton Altaparmakov
 * Copyright (c) 2002-2006 Szabolcs Szakacsits
 *
 * Copyright (c) 2006-2007 Troeglazov Gerasim (3dEyes**)
 *
 * This program/include file is free software; you can redistribute it and/or
 * modify it under the terms of the GNU General Public License as published by
 * the Free Software Foundation; either version 2 of the License, or (at your
 * option) any later version.
 *
 * This program/include file is distributed in the hope that it will be useful,
 * but WITHOUT ANY WARRANTY; without even the implied warranty of
 * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU General
 * Public License for more details.
 *
 * You should have received a copy of the GNU General Public License alongwith
 * this program (in the main directory of the Linux-NTFS distribution in the
 * file COPYING); if not, write to the Free Software Foundation,Inc., 59 Temple
 * Place, Suite 330, Boston, MA 02111-1307 USA
 */

#include "fs_func.h"

#include <ctype.h>
#include <dirent.h>
#include <errno.h>
#include <fcntl.h>
#include <stdio.h>
#include <stdlib.h>
#include <string.h>
#include <sys/stat.h>
#include <time.h>
#include <unistd.h>

#include <disk_device_manager.h>
#include <driver_settings.h>
#include <KernelExport.h>

#include <kernel.h>

#include "attributes.h"
#include "fake_attributes.h"
#include "lock.h"
#include "ntfs.h"
#include "volume_util.h"

extern int	mkntfs_main(const char *devpath, const char *label);

typedef struct identify_cookie {
	NTFS_BOOT_SECTOR boot;
	char label[MAX_PATH];
} identify_cookie;

static bool
is_device_read_only(const char *device)
{
	bool isReadOnly = false;
	device_geometry geometry;
	int fd = open(device, O_RDONLY | O_NOCACHE);
	if (fd < 0)
		return false;

	if (ioctl(fd, B_GET_GEOMETRY, &geometry) == 0)
		isReadOnly = geometry.read_only;

	close(fd);
	return isReadOnly;
}

static status_t
get_node_type(ntfs_inode* ni, int* _type)
{
	ntfs_attr* na;

	if (ni->mrec->flags & MFT_RECORD_IS_DIRECTORY) {
		// Directory
		*_type = S_IFDIR;
		return B_OK;
	} else {
		// Regular or Interix (INTX) file
		*_type = S_IFREG;

		if (ni->flags & FILE_ATTR_SYSTEM) {
			na = ntfs_attr_open(ni, AT_DATA, NULL, 0);
			if (!na)
				return ENOENT;

			// Check whether


name == NULL ? "NULL" : name);

	if (ns == NULL || dir == NULL || name == NULL) {
		result = EINVAL;
		goto exit;
	}

	if (strcmp(name, ".") == 0 || strcmp(name, "..") == 0) {
		result = EPERM;
		goto exit;
	}

	ino = ntfs_inode_lookup(_vol, dir->vnid, name);
	if (ino == (u64)-1) {
		result = EINVAL;
		goto exit;
	}

	result = get_vnode(_vol, ino, (void**)&file);
	if (result != B_NO_ERROR)
		goto exit;

	ni = ntfs_inode_open(ns->ntvol, file->vnid);
	if (ni != NULL) {
		if (!(ni->mrec->flags & MFT_RECORD_IS_DIRECTORY)) {
			result = ENOTDIR;
			goto exit;
		}
		if (ntfs_check_empty_dir(ni)<0)	{
			result = ENOTEMPTY;
			goto exit;
		}
		ntfs_inode_close(ni);
	} else {
		result = EINVAL;
		goto exit;
	}

	result = ntfs_remove(_vol, dir->vnid, name);
	if(result != B_NO_ERROR) {
		goto exit;
	}

	notify_entry_removed(ns->id, dir->vnid, name, file->vnid);

	remove_vnode(_vol, file->vnid);

	put_vnode(_vol, ino);

	dir_ni = ntfs_inode_open(ns->ntvol, dir->vnid);
	if (dir_ni != NULL) {
		fs_ntfs_update_times(_vol, dir_ni, NTFS_UPDATE_MCTIME);
		ntfs_inode_close(dir_ni);
	}

	ntfs_mark_free_space_outdated(ns);

exit:
	if (ni != NULL)
		ntfs_inode_close(ni);

	TRACE("fs_rmdir - EXIT, result is %s\n", strerror(result));

	UNLOCK_VOL(ns);

	return result;
}

status_t
fs_unlink(fs_volume *_vol, fs_vnode *_dir, const char *name)
{
	nspace *ns = (nspace*)_vol->private_volume;
	vnode *dir = (vnode*)_dir->private_node;
	vnode *file = NULL;
	ntfs_inode *dir_ni = NULL;
	status_t result    CO           NO           NOX             O3

Another idea with list comprehension and f-strings:
df.columns = [f'{k}_{v}' for k, v in df.loc[1].items()]
print (df)
  sureste_1_CO sureste_2_NO sureste_3_NOX sureste_136_O3
1           CO           NO           NOX             O3


Activation in parietal operculum parallels motor recovery in stroke.
Motor recovery after stroke requires continuous interaction of motor and somatosensory systems. Integration of somatosensory feedback with motor programs is needed for the automatic adjustment of the speed, range, and strength of the movement. We recorded somatosensory evoked fields (SEFs) to tactile finger stimulation with whole-scalp magnetoencephalography in 23 acute stroke patients at 1 week, 1 month, and 3 months after stroke to investigate how deficits in the somatosensory cortical network affect motor recovery. SEFs were generated in the contralateral primary somatosensory cortex (SI) and in the bilateral parietal opercula (PO) in controls and patients. In the patients, SI amplitude or latency did not correlate with any of the functional outcome measures used. In contrast, the contralateral PO (cPO) amplitude          + (masking_key_ ? 4 : 0);
}

WSFrame::WSFrame(const bool fin, const OpCode opcode, const string & payload)
  : header_(fin, opcode, payload.length()), payload_(payload)
{}

WSFrame::WSFrame(const bool fin, const OpCode opcode, const string & payload,
                 const uint32_t masking_key)
  : header_(fin, opcode, payload.length(), masking_key), payload_(payload)
{}

WSFrame::WSFrame(const bool fin, const OpCode opcode, string && payload)
  : header_(fin, opcode, payload.length()), payload_(move(payload))
{}

WSFrame::WSFrame(const bool fin, const OpCode opcode, string && payload,
                 const uint32_t masking_key)
  : header_(fin, opcode, payload.length(), masking_key),
    payload_(move(payload))
{}

WSFrame::WSFrame(const Chunk & chunk)
  : header_(chunk),
    payload_(chunk(header_.header_length()).to_string())
{


if (payload_.length() != header_.payload_length()) {
    throw out_of_range("payload size doesn't match the size in the header");
  }

  if (header_.masking_key()) {
    const string mk = put_field(*header_.masking_key());

    for (size_t i = 0; i < payload_.length(); i++) {
      payload_[i] ^= mk[i % 4];
    }
  }
}

string WSFrame::to_string() const
{
  string output;
  uint8_t temp_byte;

  /* first byte */
  temp_byte = (header_.fin() << 7) + static_cast<uint8_t>(header_.opcode());
  output.push_back(temp_byte);

  /* second byte */
  temp_byte = header_.masking_key() ? 1 << 7 : 0;

  if (payload_.length() <= 125u) {
    temp_byte += static_cast<uint8_t>(payload_.length());
    output.push_back(temp_byte);
  }
  else if (payload_.length() < (1u << 16)) {
  production from explants were eliminated when the tnrRPE-CM was subjected to trypsin or heat treatment, indicating that the factor(s) responsible for promoting these cellular events was most likely proteinaceous. Growth factors, including basic fibroblast growth factor, were unable to generate long neurite outgrowth or progenitor cell production as observed in RPE-CM-supplemented explant cultures. We report that CM from cultures of primary and transformed neonatal rat RPE cells promoted ganglion cell-like neurites and the production of migrating retinal progenitor cells that primarily expressed photoreceptor-specific markers, from neonatal rat retinal explants. This evidence further confirms the important role of RPE in retinal development. The production of large numbers of progenitor cells by an RPE-secreted factor(s) may have important implications for possible therapeutic approaches to help correct retinal disease states by


Features Uni-Super Ink that helps prevent against check and document fraud

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All prices listed are delivered prices from Costco Business Delivery. Merchandise can only be delivered to businesses within the greater Puget Sound, San Francisco Bay, Las Vegas, Los Angeles, San Diego, Phoenix and Atlanta metropolitan areas. Product availability and pricing are subject to change without notice.

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13/08/2018 to 14/08/2018International Conference On Pain Management & Research: Pain Management is an inspired delight to welcome all of you member who belongs anywhere throughout the world to assemble the treasured International Conference on “Pain Management & Research” which is announced to be held on August 13-14, 2018 at Rome, Italy. This global congress incorporates a scientific program by the global expert to explore the future aspect of next generation.


as an “Essbase and Planning” access type until you either ran a planning refresh, executed the provisionusers utility or the user logged into the planning application.

The existing essbase user was provisioned for the PLANSAMP planning application. This would create a new record in the CSS_PROVISONING_INFO table and the SQL generated is similar to the one shown earlier.

The users information is instantly updated in EAS so it does prove that essbase is now talking directly with Shared Services.

There is no change in regards to the user information being written to the planning applications HSP_USERS table when a user is provisioned against a planning application, it still requires the user to log in or a refresh to be run to populate the table.

The only difference is the new style nativewill accept the proposition, which is
thus made to look quite probable. For instance,
if you want to make him admit that a boy must do everything
that his father tells him to do, ask him “whether
in all things we must obey or disobey our parents.”
Or, if a thing is said to occur “often,”
ask whether by “often” you are to understand
few or many cases; and he will say “many.”
It is as though you were to put grey next black, and
call it white; or next white, and call it black.


possible horizontally transferable genetic regions associated with bacteriophages and transposons at several loci on the chromosomes of strains 2336 and 129Pt ([@B31]). The MOMP genes of the two strains were not located in these regions and it is unknown whether other mobile genetic elements were present near the MOMP genes. Nonetheless, since *H. somni* is known to enter a competence state for DNA transformation ([@B32]), the MOMP gene may be able to transfer horizontally among strains, even if it is not located on or near a mobile genetic element. Of note, in *H. influenzae*, which can also enter a competence state, horizontal transfer of the porin gene has been suggested ([@B33]). Together, these findings suggest that the phylogenetic relationships among *H. somni* isolates should be interpreted carefully inet al. ([@B27]) reported that MOMP gene exchange between *H. somni* pneumonic strain 2336 (MOMP genetic clade: Ib) and preputial strain 129Pt (MOMP genetic clade: others) affected serum susceptibility. Moreover, using mutants expressing chimeric MOMP, the authors showed that the carboxy-terminal part of the protein containing loops L4-L8 was involved in the serum susceptibility of *H. somni* ([@B27]). However, further investigations using isolates grouped into MOMP genetic clade Ia are needed to elucidate the participation of MOMP of clade Ia in the survivability of *H. somni* in the bovine blood and the development of TEME in cattle.

Conclusions {#s4}
===========

Although *H. somni* strains show genetic diversity, our results indicates that a predominant group of strains with a specific genetic background (MOMP genetic clade Ia and PFGE cluster HS1) can cause


1. Field of the Disclosure
The disclosure relates to a telephone and a method of performing a conferencing function using the telephone, and more particularly to a telephone with a video function and a method of performing a video conference using the telephone.
2. Description of Related Art
With rapid progress in communication technologies, people nowadays can communicate with one another no matter how far away they are from each other. Particularly, with the popularity of high-bandwidth internet access, a video conference system capable of transmitting image and voice tends to become the mainstream in the development of remote communication methods.
Since a computer is characterized by high peripheral compatibility, the computer plays a leading role in the common videoconferencing system, and the computer may be connected with a video camera andPHED Bihar AE Recruitment 2018

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‘Do you get seasick?’

‘Ask me in five minutes,’ Ella said faintly, allowing him to help her into the boat and settling herself in the comfortable leather seat.

Nikos pulled up the anchor, started the engine and skilfully guided the boat into deeper water. Then he eased the throttle back and the boat picked up speed.\delta\sigma(a_1,\ldots a_n)=PT^\op(\hat a)(\sigma)$$ where $\hat a:X\to SFn$ is the adjoint transpose of $(a_1,\ldots a_n):n\to UPX$, with $F\dashv U:{\mathsf{BA}}\to{\mathsf{Set}}$ being the familiar adjunction.

It is worth noting that the elements in $PT^\op SFn$ are, by the Yoneda Lemma, in one-to-one correspondence with natural transformations ${\mathsf{Set}}(-,2^n)\to{\mathsf{Set}}(T-,2)$. The latter natural transformations are also known as [*predicate liftings*]{} [@Pattinson03]. Hence we see that the logic $\mathbf L$ coincides with the logic of all predicate liftings of [@Schroder05], with the difference that the functor $\mathbf L$ also incorporates a complete set of axioms. The axioms are important to us as otherwise the natural transformation $\beta$ mentioned in the introduction, see Equation , might not exist.

Of course, in concrete examples one is often able to obtain much more succinct presentations:

\[prop:mathbf L\] For $T$ the powerset functor, the functor $\mathbf


that is, it preserves the order on the homsets: $f\leq g$ implies $Tf\leq Tg$. A ${\mathsf{Pos}}$-natural transformation between locally monotone functors is just a natural transformation, the extra condition of enriched naturality being vacuous here. Consequently, a ${\mathsf{Pos}}$-adjunction between two ${\mathsf{Pos}}$-categories is just an ordinary adjunction between two locally monotone functors. The category of ${\mathsf{Pos}}$-enriched functors from $\K$ to $\mathscr L$ and natural transformations between them will be denoted by $[\K, \mathscr L]$. The [*opposite category*]{} $\K^\mathsf{op}$ of $\K$ has just the sense of morphisms reversed, the order on hom-posets remains unchanged. To avoid overloaded notation, we shall mostly employ the same notation for a ${\mathsf{Pos}}$-category $\K$ and its [*underlying ordinary category*]{}, unless it is necessary to emphasize the distinction between them. In such case, the ordinary categorywill be denoted by $\K_o$, and we proceed similarly for ${\mathsf{Pos}}$-functors.

Besides ${\mathsf{Pos}}$ itself, an example of a ${\mathsf{Pos}}$-enriched category is ${\mathsf{Set}}$, the category of sets and functions, considered discretely enriched. In the chain $$C\dashv D\dashv V:{\mathsf{Pos}}\rightarrow {\mathsf{Set}}$$ of adjunctions between the connected components functor, the discrete functor and the forgetful one, only the adjunction $C\dashv D:{\mathsf{Set}}\to{\mathsf{Pos}}$ is enriched; in particular the discrete functor $D:{\mathsf{Set}}\to {\mathsf{Pos}}$ is locally monotone, while the forgetful functor $V:{\mathsf{Pos}}\to {\mathsf{Set}}$ fails to be so.

Observe also that, due to the discrete enrichment, [*any*]{} functor ${\mathsf{Set}}\to {\mathsf{Set}}$ is automatically locally monotone.

Weighted (co)limits; coinserters; Kan-extensions {#sec:3.C}
------------------------------------------------

Recall from [@kelly:enriched] that the proper concepts of limits and colimits in enriched category theory are those of [*weighted*]{} (co)limits. Specifically, the [*colimit*]{} of a ${\mathsf{Pos}}$ functor $G:\mathscr D \to \K$ weighted by


equalities below hold: $$\label{commut}
    b_i \circ f_j = g_j \circ a_i \ (\ i,j=1,2\ ) \quad$$

These induce the arrows $c_1, c_2, h_1, h_2$ in an obvious way. Finally, let $h_3$ be the coinserter (assuming it exists in $\mathscr C$) of $h_1$ and $h_2$, and denote by $c_3:Y_3\to Z_3$ the induced unique mediating arrow. Then:

1.  The last column is also a coinserter.

2.  If additionally the first row and columns are reflexive coinserters, then the diagonal $$\xymatrix@C=35pt{X_1 \ar@<0.35ex>[r]^{b_1\circ f_1}  \ar@<-0.35ex>[r]_{b_2\circ f_2} & Y_2 \ar[r]^{h_3\circ b_3} & Z_3 }$$ is again a coinserter, which is reflexive if the second row (column) is again a reflexive coinserter.

3.  Reflexivity of the first two rows and columns imply reflexivity of the remaining third row and column.

To seeenriched analogue of a weak pullback.

\[def:exact\] An *exact square* in the category ${\mathsf{Pos}}$ of posets, or in the category ${\mathsf{Preord}}$ of preorders, is a diagram $$\label{exact-sq}
\vcenter{
\xymatrix{
E \ar[r]^{\alpha} \ar[d]_{\beta} \ar@{}[1,1]|{\swarrow}& X\ar[d]^f \\
Y\ar[r]_g & Z}
}$$ with $f\circ \alpha\leq g\circ \beta$, such that $$\label{exact}
\forall x\in X,y\in Y.\ f(x)\leq g(y)\ \Rightarrow \exists \ w\in E.\ (x\leq \alpha(w) \land \beta(w)\leq y)$$

That the above concept generalises weak pullbacks in sets is seen as follows. An exact square of [*discrete*]{} posets is precisely a weak pullback of their underlying sets. Equivalently, the discrete functor $D:{\mathsf{Set}}\to{\mathsf{Pos}}$ maps weak pullbacks to exact squares and reflects exact squares to weak pullbacks.

Given an endofunctor $T$ of ${\mathsf{Set}}$, we shall now connect the property of preserving weak pullbacks with the preservation of exact squares by the corresponding posetification $T'$. This


or *equations* of the presentation.

We see that the format of the equations (i.e., the elements of $\Gamma _n$) requires them to be pairs in $UF\hat\Sigma U Fn\times UF\hat\Sigma U Fn$, that is, every variable must be under exactly one modal operator. Such equations are called equations, or axioms, *of rank $1$*. For example, if we wanted to *extend* ${\mathsf{DL}}$ by negation (thinking of negation as a unary modal operator), then $\neg(a\wedge b)=\neg a\vee\neg b$ and $\neg 1 = 0$ are equations of rank $1$, but $a\wedge\neg a = 0$ is not. The importance of equations of rank $1$ is that they capture algebras for a *functor* (as opposed to general equations which correspond to algebras for a monad), see Theorem \[th:5.4\] below.

For proofs of the following proposition and theoremto say that $\mathscr A$ comes equipped with a forgetful functor $\mathscr A\to{\mathsf{Pos}}$ so that $\mathscr A\to{\mathsf{Pos}}$ is an ordered variety and $\mathscr A_o\to{\mathsf{Pos}}_o\to{\mathsf{Set}}$ is an ordinary variety. If $L$ has an ordered presentation then it preserves enriched sifted colimits, hence $L_o$ preserves ordinary sifted colimits, hence $L_o$ has a presentation.

We can now conclude what we shall need to know about functors on ${\mathsf{DL}}$.

\[thm:presentmonop\] For a locally monotone functor $L':{\mathsf{DL}}\to{\mathsf{DL}}$ the following are equivalent:

1.  $L'$ has a presentation by monotone operations and equations.

2.  $L'$ preserves ${\mathsf{Pos}}$-enriched sifted colimits.

3.  $L'$ is the ${\mathsf{Pos}}$-enriched left Kan extension of its restriction to discretely finitely generated free distributive lattices.

As in Proposition \[prop:mathbf L\], we now obtain that

\[cor:L’isboldL’\] If $T'$ is the the convex powerset functor, then the functor $L'$ of


the underlying ordinary categories ${\mathsf{Set}}_o$, ${\mathsf{DL}}_o$, ${\mathsf{BA}}_o$ are also locally finitely presentable, it follows from [@kelly:lfp] that the finitely presentable objects in all the above categories are precisely the same as in the ordinary case i.e., the ones for which the underlying sets are finite. Note that we have the following commuting diagram $$\label{eq:square_of_transformations}
\xymatrix{
S_f\dashv P_f \ar[0,2]^-{(D_f^\op,W_f)}
 \ar[1,0]_{(I^\op,J)} & & S'_f \dashv P'_f \ar[1,0]^{(I'^\op,J')} \\
 S\dashv P \ar[0,2]_-{(D^\op,W)} & & S'\dashv P'
 }$$ in the category of transformations of adjoints.

Define now $(\bar L,\bar{\delta})$ for $T$ as $$\bar L=\Lan_J(PT^\op S J) \qquad \mbox{ and } \qquad \bar{\delta}:\bar LP \to PT^{op}$$ as the adjoint transpose of $\bar L\to  PT^\op S$ arising from the universal property of the left Kan extension $\bar L$. By construction, $\bar L$ is finitary and is , (010,010) *+{\{0,1,\top\}} = "t"
   , (010,-20) *+{\emptyset} = "bb"
\POS "bb" \ar@{-} "b"
\POS "b" \ar@{-} "l"
\POS "b" \ar@{-} "r"
\POS "l" \ar@{-} "t"
\POS "r" \ar@{-} "t"
\endxy$$ Then it is easy to see that $\bar L'P'e: \bar L'P'X\to \bar L'P'D2$ fails to be surjective (since $\bar L'P'D2$ has four elements and $\bar L'P'X$ only two elements). Hence $\bar L'P'e$ is not the coinserter in ${\mathsf{DL}}$ of the parallel pair $\bar L'P'f$, $\bar L'P'g$.

Although the locally monotone functor $\bar L'=WK$ fails to preserve reflexive coinserters, it is however finitary, being a composite of such. Indeed, $W$ is left adjoint, while for $K$ notice the following: $K$ is a right adjoint functor between locally finitely presentable categories, whose left adjoint $W$ preserves finitely


inserters) and maps finite distributive lattices to finite posets; $T'^\op$ preserves coreflexive inserters of finite posets by hypothesis, and $P'$ sends them to reflexive coinserters, due to Proposition \[P’corefl eq\]. Our claim now follows from Theorem \[thm:DLffisdense\] and [@kelly:enriched Theorem 5.29].

As a result about modal logics, the theorem can be reformulated as follows.

\[cor:strong\] Let $T$ be an endofunctor on ${\mathsf{Set}}$ and $T'$ a ${\mathsf{Pos}}$-extension of $T$ which *preserves coreflexive inserters*. Then $(\bar L', \bar{\delta}')$ and $(\mathbf L', \boldsymbol \delta ')$ coincide. In particular, it follows from Proposition \[prop:canonical\_finitary\_fragment\] that $\mathbf L'$ is *the maximal positive fragment* of $\mathbf L$.

The next example shows what can go wrong in case that $T'$ does not preserve coreflexive inserters.

For $T={\mathsf{Id}}$, the corresponding finitary logics is $\mathbf L={\mathsf{Id}}$ on ${\mathsf{BA}}$, with trivial semantics $\boldsymbol \delta:LP\to PT^\op$. It(1998)

A. Balan and A. Kurz, Finitary functors: from [Set]{} to [Preord]{} and [Poset]{}. In: A. Corradini et al (eds.), , LNCS **6859**, [85–99]{}, Springer, Heidelberg (2011)

A. Balan, A. Kurz and J. Velebil, Positive fragments of coalgebraic logics. In: R. Heckel and S. Milius (eds.), , LNCS **8089**, [51–65]{}, Springer, Heidelberg (2013)

M. Barr, Relational algebras. In: S. MacLane et al (eds.), , LNM **137**, [39–55]{}, Springer, Heidelberg (1970)

N. Bezhanishvili and S. Ghilardi, The bounded proof property via step algebras and step frames. *Ann. Pure Appl. Logic* **165**:[1832–1863]{} (2014)

M. Bílková, A. Kurz, D. Petrişan and J. Velebil, Relation liftings on preorders. In: A. Corradini et al (eds.) , LNCS **6859**, [115–129]{}, Springer, Heidelberg (2011)

G. J. Bird, , PhD Thesis, Univ. of Sydney (1984)

G. Birkhoff, . Amer. Math. Soc. (1967)

P. Blackburn, M. de Rijke and Y. Venema, . Cambridge Tracts in Theor. Comput. Sci. **53**, Cambridge Univ. Press (2002)

S. L. Bloom, Varieties


pursued, having looked at what's out there right now -- are there possibilities of genuine crimes as opposed to really bad policies. And I think it's important-- one of the things we've got to figure out in our political culture generally is distinguishing betyween really dumb policies and policies that rise to the level of criminal activity. You know, I often get questions about impeachment at town hall meetings and I've said that is not something I think would be fruitful to pursue because I think that impeachment is something that should be reserved for exceptional circumstances. Now, if I found out that there were high officials who knowingly, consciously broke existing laws, engaged in coverups of those crimes with knowledge forefront, then I think a basic principlexDataTOM_subAxesType_intepolationAxes ) {
        if( interpolation == NULL ) {
            smr_setReportError2p( smr, xDataTOM_smrLibraryID, -1, "Interpolation must not be NULL for intepolationAxes" );
            return( 1 );
        }
        if( xDataTOM_interpolation_copy( smr, &(subAxes->interpolation), interpolation ) ) return( 1 ); }
    else {      /* Not used but fill in anyway. */
        xDataTOM_interpolation_set( smr, &(subAxes->interpolation), xDataTOM_interpolationFlag_linear, xDataTOM_interpolationFlag_linear,
            xDataTOM_interpolationQualifier_none );
    }


"""
        Setter for fuzzy matching mode
        :param is_fuzzy: boolean
        """
        self.config['main']['fuzzy_match'] = is_fuzzy
        self.completer.set_fuzzy_match(is_fuzzy)

    def get_fuzzy_match(self):
        """
        Getter for fuzzy matching mode
        :return: boolean
        """
        return self.config['main'].as_bool('fuzzy_match')

    def set_long_options(self, is_long):
        """
        Setter for long option names.
  data therefrom.
Generated by the buffer 13 from the external clock signal CK used as a trigger signal, the internal clock signal CLK inevitably has a skew with respect to the external clock signal CK. It is the internal clock CLK that controls the circuits 14 to 16. To transfer data between the memory 11 and the CPU 12, the circuits 14 to 16 must be controlled so as to compensate for the skew the signal CLK has with respect to the signal CK. This technique, however, results in a reduction of the data transfer speed.
Recently, various methods of minimizing or eliminating the skew have been developed. Two of these methods will be described below.
The first method is to use a PLL (Phase-Lock Loop) to detect the skew, and


the speaker is concerned primarily to make a metaphoric and ironic point, respectively, not a hyperbolic one. This means that hyperbole doesn't lend a substantive content to the mixture in the way metaphor does in ironic metaphor. Instead, the hyperbole modulates the working of the figure it mixes with, so that it intensifies its effects. Thus, we can think of the contribution made by hyperbole as an interpretive effect that infuses hyperbolic tinges into the figure it mixes with. 2 Hyperbolic figures It is very common for hyperbole to mix with other figures of speech within a single utterance. Carston and Wearing (2015: 81) list some examples: (2) That child is the devil incarnate. (hyperbole and metaphor) (3) They go about together like Siamese twins. (hyperbole and simile)people's thoughts and expectations. As Carston & Wearing note, a hyperbolic speaker is expressing that she finds the situation she is describing to "have (much) more of some property than she expected or wanted" (2015: 90). This is something that transpires in typical paraphrases of hyperboles along the lines that there is "more or less of [some property] F than the speaker expected (or wanted).[...] the paraphrase of what the speaker meant doesn't merely capture a quantity or degree which is more factually accurate than the encoded quantity; it also expresses an element of evaluation of the state of affairs described" (2015: 85). This is very much on the right line; however Carston and Wearing are not explicit about how this evaluation comes about. Walton (2017) provides precisely


the solution I'm looking for.
There might be something wrong with the binding.
I have looked at several other posts, read material and book chapters on Dependency Properties and binding and I can't find any obvious mistake. I have even used snoop but didn't get any additional information from that too.
Some of the things I've looked at are given below
BindingExpression path error: property not found on 'object'
System.Windows.Data Error: 40 : BindingExpression path error: property not found on object
WPF Error 40 BindingExpression path error: property not found on 'object'
http://wpftutorial.net/DependencyProperties.html
http://rachel53461.wordpress.com/2012/07/14/what-is-this-datacontext-you-speak-of/
Is there a way to determine where a WPF Binding is declared/created?
WPF slow performance - many DataItem=null binding warnings
Any ideas of what could be going wrong and how I can get rid of the error?

A:

WPF binding errors aren't always the easiest thing tofor his decadent lifestyle and had few followers, but he became a cult figure. The Vril Gesellschaft was the inner core of Thule during the 3rd Reich. However for a really strong esoteric understanding of Runes, it is also important to have a working knowledge of the themes behind Indo-European cultures in general, so you can see the overall cultural context of Runology and Rune Magick at least. " Ecclesiastes 12:12. com - "…Vril was known to these mystics as a natural and abundant energy, having disseminated it's divine wisdom world wide under many names. Unsavoury Products is the fifth full-length studio album by The Black Dog featuring Parisian spoken word artist Black Sifichi. Paul, Minn. 28 "Super voodoo" spells and rituals for love. From these humble beginnings


pure form, however, the shaman or magician is not in need of spirits and other entities. The Vril Societies. Short Wave Lies 19. Rating: 5 out of 5 stars (5/5) Vril Mastery: Harness the Force of the Gods. Occult Books. Historian Nicholas Goodrick-Clarke's 1985 book, The Occult Roots of Nazism, discussed the possibility of links between the ideas of the Occult and those of Nazism. Allegedly, these aliens had visited Earth and settled in Sumeria, and the word Vril was formed from the ancient Sumerian word "Vri. AW: Books on Vril and the Black Sun? Es geht um "Vril", um die geheimnisvolle Urkraft, Raumkraft und Lebensenergie. We agree with him. VRIL: The Power of the Coming Race. People who have studied about the Thule society say that itVril Force or Vril Energy was said to be derived from the Black Sun, a big ball of "Prima Materia" which supposedly exists in the center of the Earth, giving light to the Vril-ya and putting out radiation in the form of Vril. The Vril Society gave secret revelations, the coming of the New Age, the return of the spear of destiny, the return of the magic black-violet stone, and black iron dagger in the old. The association of Nazism with occultism occurs in a range of theories, speculation and research into the origins of Nazism and into Nazism's possible relationship with various occult traditions. Documentary explores the potential influences that formed the society. 30 "Super voodoo" love luck mojo bag. Originally known as "Ashtar. 14 where can


vril be found. uk, 26 February 2018 Page 2 of 10 Contents and train of thoughts Vril is the occult power behind the forces of matter and their common origin. It usually is used to refer to a sort of cosmic energy that was utilized by a race called the Hyperboreans to perform great spiritual feats and power very advanced technology. This intense interest in the occult and the arcane led to the significant expansion of a secret. Law of Reciprocity: You Will Receive In Like Measure According To The Spiritual Competence Of The Attunement Giver! Workshops Founded By Victor Glanckopf. Ultimately, I. The Vril Force or Vril Energy was said to be derived from the 'Black Sun', - represented as a Swastika made up of Sig runes- which supposedly exists in the center of the Earth, giving light to the Vril-ya and putting out radiation in the form of Vril. 4 the rise of the vril society. The Vril Society was also known as the Lodge of Light, and as the Luminous Lodge. It really begins with a story about acceptance. This is one of the earliest Giegling releases, the first release on Giegling's now defunct Staub Series, and also Vril's first release ever. and the Freemasons were banned and some of their members arrested. black magick, occult, vril, thule, satanic magick, military occultism, anti. Otti Votavova said that Hitler belonged to the legendary "FOCG" or "99 Lodge" of black magick, described in Frabato The Magician and Fire And Ice (see the bibliography). Magick


in Your Pocket: Magical Spells You Can Cast Anywhere, Even in Your Pocket! Author Charles Mage. Black Magick is the art that will not allow itself to be seen nor activated by the profane. " This law has a threefold nature: When a magician is in the process of working magick, he utilizes, concentrates, and builds up Astral Light in his mental sphere…. In its pure form, however, the shaman or magician is not in need of spirits and other entities. Historian Nicholas Goodrick-Clarke's 1985 book, The Occult Roots of Nazism, discussed the possibility of links between the ideas of the Occult and those of Nazism. The end of World War I had left Germany with its people poor and its morale low. Vril also made plans toworking magick, he utilizes, concentrates, and builds up Astral Light in his mental sphere (Above). When used especially well, this form of magick is particularly effective against Greyfaces, as they may not even know that they are being manipulated. My birth name is Thomas. According to Zee, the narrator's host, Vril can be changed into the mightiest agency over all types of matter, both animate and inanimate. One thing that every mystery religion, secret society, the New Age, the magickal craft, etc. Vril is the occult power of sound. Vril can be harnessed by use of the Vril staff or mental concentration. CCTV Nation. 4 the new age of vril. Occult Alliance Nazis Hitler Thule Tibettan Buddhism Vril nwo illuminati freemasons Item Preview remove-circle Share or Embed This


of spring when day and night are of equal length. Aleister Crowley, original name Edward Alexander Crowley, (born October 12, 1875, Royal Leamington Spa, England—died December 1, 1947, Hastings), British occultist, writer, and mountaineer, who was a practitioner of " magick" (as he spelled it) and called himself the Beast 666. Visionary Shamanism; The Secret History of Poltergeists and Haunted Houses; Power Crystals; Lords of the Left-Hand Path; Vampyre Magick. Magick can be categorized into 3 models: Mental model; Energy Model; Spirit Model; The key occult doctrine of Magick is the Hermetic Law: "As Above, So Below. We use cookies to offer you a better browsing experience and to analyze site traffic. Garver, 1894 (PDF 490 KB). The vril maidens are hot and into sex magick. Chaos Magicseems to relate to the aether (at least imo) and this may actually be what is being referred to. Face: An aspect of Discordian Magick; the category of magick Nature: The end-product of Discordian Magick Hodge: The pseudo-Zen force of Order in the world Podge: The pseudo-Zen force of Chaos in the world The Doctrine: things have a tendency to work out ok in the end Ju-Ju: The "aftershocks" of Discordian Magick; the long-term effects. [link to youtu. But energy is a good metaphor. The Aryan Solar God, and the Age of Aries Aries is a typical Indo-European (Aryan) god of war and equates to the Roman Mars, the Germanic Thor/Thunor/Donar, Tyr, the Celtic Teutates and the Vedic Indra. The kings of old (especially the Merovingian Kings) knew


The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper and its Supporting Information files.

Introduction {#s1}
============

Although the five-year survival for multiple myeloma (MM) patients has gradually increased over the last decades, especially with the use of high-dose chemotherapy and novel agents such as protease inhibitors and immunomodulatory drugs (IMiDs), MM is still considered incurable by conventional means. For the majority of patients the goal of therapy i.e. prolonged survival and preventing progression is related to the quality of response to initial therapy and depth of remissions reached [@pone.0101819-ChananKhan1], [@pone.0101819-Dingli1].

Renal impairment (RI) is a relatively common feature of MM both at diagnosis and in relapsed/refractory MM [@pone.0101819-Alexanian1]. With the use of conventional chemotherapy, it has been shown inon response to treatment, time to next treatment (TTNT) and most importantly survival in the era of novel agents (i.e. bortezomib, lenalidomide and thalidomide). In this retrospective study, we demonstrate that the use of novel drugs, especially bortezomib can effectively improve response, increase TTNT and enhance overall survival (OS) in multiple myeloma patients with renal impairment.

Materials and Methods {#s2}
=====================

Study population {#s2a}
----------------

Consecutive patients diagnosed with MM between January 2000 and June 2011 at 7 university clinics, 5 regional centers and 3 local hospitals in Sweden were included. All patients were identified from the Swedish Cancer Registry, which covers 96.3% of all individuals with malignant disease [@pone.0101819-Barlow1]. Patients were excluded if they had non-treatment demanding disease (watch and wait), plasma cell leukemia or solitary plasmacytoma. All data were collected from


[@pone.0101819-Blade1]. Time to next treatment was defined as the time between the start date of the current treatment line and the start date of the next treatment line, death or last follow-up. OS was calculated from the start of the treatment until death or last follow-up.

Renal response was assessed according to the criteria suggested by Ludwig et al and the International Myeloma Group as either a complete response (CRrenal) defined as an improvement of GFR from \<50 mL/min at baseline to ≥60 mL/min; a partial response (PRrenal) defined as an improvement of GFR from \<15 mL/min at baseline to 30--59 mL/min; a minimal response (MRrenal) defined as an improvement of GFR from \<15 mL/min at baseline to 15--29 mL/min or from 15--29 mL/min to 30--59 mL/min; or other,between the degree of RI and OS ([Fig. 2B](#pone-0101819-g002){ref-type="fig"}).

![Overall survival in symptomatic multiple myeloma patients.\
(A) Patients presenting with renal impairment compared to those with normal renal function. (B) Patients divided into five groups according to the chronic kidney disease classification.](pone.0101819.g002){#pone-0101819-g002}

In the non-HDT group the existence of renal failure correlated with impaired OS (25 versus 37 months, *P*\<0.001). Novel drugs in 1^st^ line significantly improved the median OS in this group ([Fig. 3A](#pone-0101819-g003){ref-type="fig"}). The difference was still highly significant (*P*\<0.001) after correction for age, calcium, hemoglobin and albumin in multivariate analysis. The same improvement was seen when analyzing only the bortezomib treated patients ([Fig. 3B](#pone-0101819-g003){ref-type="fig"}). Both the univariate and the multivariate analysis showed that bortezomib treatment was an independent factor affecting OS ([Tables S1](#pone.0101819.s001){ref-type="supplementary-material"} and [S2](#pone.0101819.s002){ref-type="supplementary-material"}). On the other


at local hospitals, it is also impossible to avoid some degree of selection bias in the choice of treatment. One weakness of this study is the lack of information about concomitant diseases, thus making it impossible to correct for comorbidity. However, the results were stratified according to age, sex, type of MM and important laboratory values at diagnosis in an attempt to cover the majority of possible differences between the groups.

Nevertheless, our results concur with earlier studies. A subgroup analysis of patients with RI enrolled in the VISTA study (bortezomib plus melphalan and prednisone versus melphalan and prednisone to previously untreated patients) reports a higher myeloma response rate as well as a longer time to progression and a better OS in the bortezomib plus melphalan and prednisone group  district   court’s

application of a 2-level sentencing enhancement for possession of

a dangerous weapon in connection with the offense to which he pled

guilty.   On January 20, 2002, Embree signed a plea agreement with

the Government in which he agreed to plead guilty to Count Two of

a multiple count indictment, which charged him with conspiracy to

possess with intent to distribute and distribute more than 500

grams of a mixture of methamphetamine in violation of 21 U.S.C. §§

846 and 841(b)(1)(A).        Embree was sentenced to 125 months in

prison.     The court entered an Amended Final Judgment Order on

September 19, 2006.       Embree timely appealed.    On appeal, Embree

contends that the Government breached


                           2
carried handguns and a concealed knife in “like a shoulder harness”

during drug transactions.     The investigation revealed that Embree

loaned money to Donna Richardson to finance her trips to California

to purchase methamphetamine. Embree and Richardson would then

distribute the methamphetamine that was purchased to friends and

co-workers.   After Embree became upset at a loss of money, he ended

his attempts to obtain methamphetamine in California and began

attempts to manufacture his own methamphetamine.

     On June 29, 2001, Embree was arrested by DEA agents at his

residence.    At the time of Embree’s arrest, a 6-8 inch   officer.    Based      on   the   available

information about the knife, gun holster and alleged firearms, the

probation officer recommended a 2-level enhancement for possession

of dangerous weapons in connection with the offense pursuant to

U.S.S.G. § 2D1.1(b)(1).      The PSR also included a 3-level deduction

for acceptance of responsibility pursuant to U.S.S.G. § 3E1.1(a).

Embree objected to the finding in the PSR regarding possession of

dangerous firearms and a knife in connection with the offense,

arguing that he never carried any guns on his person or in his

vehicle, and that the knife was used in his auto repair business.

The   United    States   objected    to    Embree


 He also testified that Embree stated that

he had manufactured methamphetamine on one occasion.                     Finally,

     1
      Embree’s initial counsel died after Embree signed the plea
agreement, but before he entered his plea of guilty. As a result
of the reassignment of counsel, at the time of his sentencing
hearing on May 29, 2002, Embree had not yet had the opportunity to
be debriefed by the Government.

                                     enhancement     at    sentencing.         The   Government

contends that the plea agreement contains no stipulations or

agreements relating to the application of the dangerous weapons

enhancement under U.S.S.G. § 2D1.1, and that, therefore, it is not

in breach of the agreement by arguing for the enhancement at

sentencing.

     Although       plea    agreements        between   the       Government    and a

defendant     are    unique         and   call    for      special


no longer bound by the terms of the

plea   agreement   because   Peglera      testified   that    he     personally

distributed only powder cocaine, and not the cocaine base for which

he pled guilty.    Id. at 412-13.    In Peglera, we held that while the

Government’s    argument     had    considerable      force        under   some

circumstances, it failed in this instance because the agreement

expressly reserved Peglera’s right to argue that the “Schedule II

narcotic    controlled   substance     for   which   (See People v. Bolinski (1968) 260 Cal.App.2d 705, 722.)

                                                 2
                                 REVIEW ON APPEAL
       The court granted defendant’s request to terminate PRCS on February 11, 2015,
but did not terminate his parole. As such, defendant remained on parole through
December 19, 2014. The court did


ages. The real interesting info in
this whole history is why it was ignored for so long, and who monetized it
later one (hint: i doubt it was the teenage kid)

------
woodchuck64
Why can't Russia give these incredibly talented teenagers something productive
to do like starting a company?

~~~
SpaceRaccoon
They are trying to. Check out the "Skolkovo innovation center". Hopefully some
day in the future you'll be buying smartphones and running software from my
country, and people will stop asking me if my parents are alcoholics and if I
want some raw potatoes.

But 'tis enough ranting, my borsch is getting cold.

~~~
ye
Ha.

Skolkovo is just another way to steal money from the taxpayers under the guise
of innovation. Which they already did: $3.72 billion dollars (125 bullion
rubles).

[http://www.themoscowtimes.com/news/article/skolkovo-
warned-o...](http://www.themoscowtimes.com/news/article/skolkovo-warned-over-
potential-4bln-in-misspending/488793.html)

~~~
SpaceRaccoon
Well corruption is a given, but at least there will be something to show for
it.

Thethis species within it was confirmed. However species within the genus Notoreas are currently regarded as being in need of revision. The holotype specimen is held at the Natural History Museum, London.

Description
Meyrick described the species as follows:
N. hexaleuca is similar in appearance to N. isoleuca and N. mechanitis. It can be distinguished from N. isoleuca as it has a less hairy thorax. N. hexaleuca also has visually different curved or straight lines on its forewings giving it a lighter appearance than N. isoleuca. N. hexaleuca can be distinguished from N. mechanitis as it is smaller in size and has longer pectinations on its antennae.

Distribution
This species is endemic to New Zealand. Other than the type locality of Ben Lomond, N. hexaleuca has also been found at Flagstaff hill


Article content continued

The touchdown dance said it all.

“I was definitely excited,” Michel said with a chuckle. “It’s one of those things where you just have to have fun with it and enjoy the game and try not to create such a big situation in your head.

“I just want to stay grounded and have fun.”

Yes, Michel’s touchdown helped give the Stampeders a 39-1 lead and arguably was a small part of a very lopsided score.

And, yes, the rest of the game was a complete train wreck for the Tiger-Cats.

But you’d be hard pressed to find any football player that doesn’t like to make plays, regardless of the situation on the line.

For his efforts, Michel earned the CFL’s player-of-the-week nod — the second straight week a Stampeder was given thefitting that Barbados is celebrating its golden jubilee during the DLP reign.

“In the 1961 manifesto to the DLP which brought Barrow to office, it was made very clear that the road to Barbados’ destiny was their own independence and from that ideal we should not retreat,” said Stuart. “There is an indissoluble connection between Barbados, Barrow and independence. That is why it is also very important that the party that Barrow formed and led should be in office at the time that the country is celebrating 50 years of independence.”

Stuart, who was sworn in as Barbados’ seventh Prime Minister in 2010 following the death of David Thompson, said the faith Barrow placed in Barbadians 50 years ago is justified.

“Independence has worked for us and we can look forward


likely to lead to catalyst deactivation as a result of Zn loss and regulatory barrier, due to toxicity of Cr. Other base metal catalysts have simply not been able to achieve acceptable levels of pollutant reduction.
Additionally, one area where such a catalyst would be extremely beneficial is with the treatment of exhaust from motorcycles. Motorcycles are more affordable alternatives to automobiles, and as such have become very popular. This is particularly true for some areas of the world, especially in parts of Asia where motorcycles have become extremely popular, and outnumber cars. Thus, there is still a need for an affordable, yet effective, catalyst. In particular, there is a need for such a catalyst for mobile source applications, especially for motorcycles.--------------------------------- -- ---------- ------- -- -------------

WBC: white blood cell count, Neu: neutrophil, Lym: lymphocyte, Mono: monocyte, Eos: eosinophil, Baso: basophil, RBC: red blood cell count, Hb: hemoglobin, Plt: platelet, TP: total protein, Alb: albumin, LDH: lactate delydrogenase, AST: aspartate aminotransferase, ALT: alanine aminotransferase, T-Bil: total bilirubin, BUN: blood urea nitrogen, Cre: creatinine, KL-6: Sialylated carbohydrate antigen Krebs von den Lungen-6, SP-D: surfactant protein-D, CRP: C reacting protein, ANA: anti-nuclear antibody, PR3-ANCA: proteinase3-anti-neutrophil cytoplasmic antibody, MPO-ANCA: myeloperoxidase-anti-neutrophil cytoplasmic antibody, C. pneumoniae: Chlamydophila pneumoniae

![Histology of transbronchial lung biopsy specimen: Alveolar tissue with macrophage aggregation and interstitial tissue with mild lymphocytic infiltration were recognized (Hematoxylin and Eosin staining, ×400).](1349-7235-58-3019-g002){#g002}

Although antibiotics and steroids were not administered, malaise, cough, hypoxemia and interstitial shadows gradually decreased up to Day 33. The patient was discharged


---
abstract: 'We explore the problem of stabilization of unstable periodic orbits in discrete nonlinear dynamical systems. This work proposes the generalization of predictive control method for resolving the stabilization problem. Our method embodies the development of control method proposed by B.T. Polyak. The control we propose uses a linear (convex) combination of iterated functions. With the proposed method auxiliary, the problem of robust cycle stabilization for various cases of its multipliers localization is solved. An algorithm for finding a given length cycle when its multipliers are known is described as a particular case of our method application. Also, we present numerical simulation results for some well-known mappings and the possibility of further generalization of this method.'
address:
- |
    Department of Applied Mathematics\
    Odessa$\prod\limits_{j=1}^Tf'\left(\eta_{T-j+1}\right)$ is called the Jacobi matrix of the cycle $\left\{\eta_1,\dots,\eta_T\right\}.$ Typically, a priori the cycles of the system are not known. Consequently, the spectrum $\left\{\mu_1,\dots,\mu_m\right\}$ of the matrix $\prod\limits_{j=1}^Tf'\left(\eta_{T-j+1}\right)$ is unknown as well. The spectrum elements are called cycle multipliers. Below, we assume that some estimates on the localization set $M$ for the cycle multipliers are known.

Let us consider the control system $$\label{2}
x_{n+1}=F\left(x_n\right),$$ where $F(x)=\sum\limits_{j=1}^N\theta_jf^{((j-1)T+1)}(x)$, $f^{(1)}(x)=f(x)$, $f^{(k)}(x)=f\left(f^{(k-1)}(x)\right)$, $k=2,\dots,T$. The numbers $\theta_1,\dots,\theta_N$ are real. It can be easily verified that at $\sum\limits_{j=1}^N\theta_j=1$ the system also includes the cycle $\left\{\eta_1,\dots,\eta_T\right\}$. We aim to choose such parameter $N$ and coefficients $\left\{\theta_1,\dots\theta_N\right\}$ so that the system cycle $\left\{\eta_1,\dots,\eta_T\right\}$ would be locally asymptotically stable. Naturally, when constructing these coefficients, there will be used information on set $M$ of multipliers localization. It is also


chaos to order: Methodologies, Perspectives and Application. World Scientific, Singapore (1999)

Davidchack R.L.,, Lai Y.-C., Klebanoff A., Bollt E.M., Towards complete detection of unstable periodic orbits in chaotic systems, Phys. Lett. A 287 (2001), 99–104.

Devaney R L. An Introduction to Chaotic Dynamical Systems. New York: Addison-Wesley Publ. Co., Second Edition., (1993)

Dmitrishin D., Hagelstein P., Khamitova A., and Stokolos A. Limitations of Robust Stability of a Linear Delayed Feedback Control, SIAM J. Control Optim. 56, (2018), 148-157.

Dmitrishin D. and Khamitova A. Methods of harmonic analysis in nonlinear dynamics, Comptes Rendus Mathematique, Volume 351, Issues 9-10, 367 - 370 (2013)

Dmitrishin D., Khamitova A. and Stokolos A. Fejér polynomials and chaos, Springer Proceedings in Mathematics and Statistics, 108 (2014), 49–75.

Dmitrishin D., Skrinnik I., Lesaja G., Stokolos A. A new method for findinga pan surface that is only close to boiling water temperature or something, and that's not high enough to cause significant Maillard browning in a reasonable amount of time.
The surface of the meat will gradually come up to boiling temperature, requiring a fairly large amount of energy.  That won't allow the pan surface temperature to recover significantly for a while.
Once the meat surface hits 212F/100C, the water in the surface meat needs to boil off.  It takes a huge amount of energy to evaporate water compared to the amount of energy it takes to raise the temperature.  While that's going on, the meat will get "stuck" at boiling temperatures for a while.  (This is quite visible, for example, when you crowd a


recent systematic review, conducted by our research group, suggested that quantitative research on this topic mostly addressed very specific variables (eg, self-disclosure at work being the only SMB) and produced only piecemeal insights or no asthma-specific evidence.[@R12] Qualitative approaches allow for a better understanding of the matter because of their open, flexible and interactive approach to data collection. To our knowledge, two qualitative studies have to date addressed asthma SMB in the workplace context. The first study, by Boot *et al*,[@R13] described different adaptation profiles among employees with asthma or chronic obstructive pulmonary disease (COPD). The authors referred to possible interactions between working conditions and asthma SMB--for example, a lack of staff replacement in case of sick leave related to a reluctance to take sick leave--but concrete examples wereIn case of discrepancy, decisions were discussed until consensus was achieved.

Patient involvement {#s2d}
-------------------

Patients were neither involved in the designing of our study nor involved in data analyses. The results were disseminated to all patients who agreed to receive such information.

Results {#s3}
=======

In total, 27 qualitative interviews were conducted and entered content analysis. One person did not return the background questionnaire. Participants were aged between 41 and 62 years, and more than half were women (n=15). Most participants worked full time. [Table 1](#T1){ref-type="table"} depicts further characteristics of our sample which was fairly heterogeneous, for example, concerning school degrees or job-related demands. The following examples for jobs with cognitive or psychosocial demands emerged: secretary, interpreter or kindergarten manager. Jobs with primarily physical demands included order picker, stockman or mail carrier. Examples of mixed


lack of instrumental support as demanding. This included lack of support either by colleagues (who, eg, would not take over a certain task; quote 11), line managers (who, eg, would not accept the colleagues taking over a certain task; quote 12) or the employer (who, eg, did not comply with certain modifications that may help to reduce exposure to triggers; quote 13).

> Quote 12: She said, for instance: "Now you have been at the counter all morning, now you can do this and that". Well, she didn't care if one does not feel well. She did not show consideration. The colleagues did, but the store manager did not.

A lot of participants also referred to the fact that low control over the types of tasks and when and how towell-being or offered assistance (quote 28). The physical display of asthma symptoms (eg, coughing or wheezing) or asthma SMB (eg, breathing techniques or using the rescue medication inhaler) was considered a stressor by some employees, especially among those working with clients (quote 29). Participants expressed the concern that any persistent coughing may be interpreted by colleagues or clients as a sign that they suffer from an acute and transmittable disease (quote 30). Generally, several participants described the need to be considered as functioning and healthy, and that they, therefore, concealed their asthma symptoms or SMBs (quote 31).

> Quote 31: Well, at work, I avoid making things public. Too many questions. Weakness? No idea. I want to be considered as healthy.

Acute symptom management: specific SMBs {#s3e}
---------------------------------------

The experience and severity of acute


asthma symptoms vary between patients. This results in a range of strategies to cope with them. When suffering from acute asthma symptoms, a lot of our participants subjectively benefited from taking deep breaths of fresh air, an SMB easily implemented by some (quote 32), but more troublesome for others who--in rare cases--had to violate safety rules at work to ensure the preferred ventilation in their rooms (quote 33). The inhalation of reliever medication was also an important SMB to the participants (quote 34), in single cases, such use was promoted by colleagues, for instance, by those coworkers who suffered from a chronic condition themselves (quote 35). Others benefited from an own office so that the rescue medication inhaler could be used in privacy (quote 36).

> Quote 35: When thereoffer them more understanding and support. However, not only the mere self-disclosure itself but also the addressee is of importance: in this respect, our observations confirmed another finding by Zhao *et al* [@R11] who stated that, generally, employees with asthma disclosed their condition more frequently to colleagues than to line managers. The reasons for limited self-disclosure ranged from feeling ashamed to fear of job loss. Some of our participants tended to hide their asthma symptoms and SMBs out of their need to appear functional and healthy. This is also in keeping with the evidence by Zhao *et al* [@R11] who found that limited privacy at the workplace impaired acute asthma symptom management at work, for example, medication use. The reasons were reported to be self-consciousness, embarrassment and inconvenience.[@R11] A link to


stunning achievement when compared to the standards of your average action MMO. This is easily one of the most ambitious online games ever - and setting aside some launch issues, one that lives up to its impossible promises.

Fighting in an open world feels strange - not as intimidating as you'd expect, but far more than just a gimmick. For the most part, standard first-person shooter rules apply. Shooting is skill-based rather than reliant on arbitrary levels. If you don't want to be shot, you get behind cover. Returning fire can be done from the hip, but you generally want to take advantage of iron sights and sniper scopes to deal out more accurate shots and hit distant enemies. It's a shooter. You've played shooters before. The twist hereis that, instead of existing as isolated maps, battlegrounds emerge organically as boundaries shift. Today, that bridge over a canyon is simply a handy route between outposts. Tomorrow, it might be a sea of tanks, with infantry crawling all over the scenery like ants.

Being in an open world, anyone who wants to take part can do exactly that. There are no lobbies, no queues, no arbitrary restrictions on numbers or how much you're allowed to bring into battle - not overt ones, anyway. An Instant Action button will spirit over anyone who requests a teleport, but you can just as easily spot something happening and head over under your own steam.

"The sheer scale of the battles is stunning - to the point that, while it makes sense for


up your in-game resource generation and guns with which to shoot people in the head for the crime of wearing the wrong colour armour. These are expensive, with new guns costing around £4 each (500-700 Sony funbucks) and each class having several slots to fill up with new weapons.

PlanetSide 2 lets you make female soldiers, who get exactly the same armour style as the men. Sony, you win a cookie. In fact, take two.

Your starting load-out is respectable though - and while I'm sure it's not deliberate, any temptation to spend a fortune in the store is swiftly dampened by most of its gear being bland variations on stock themes like 'assault rifle' and 'pistol'. There's nothing as iconic as the Tribes spinfusor, and nothing particularly sexy ifit's worth putting those fears on the back burner. There'll be time enough tomorrow to worry about the grand game and its future.

What matters today is that as a mix of shooter and MMO, PlanetSide 2 is nothing short of a triumph: not quite the best of both worlds, but certainly the best attempt anyone has ever made to fuse them together. Alone, it's worth checking out just to witness its epic scale for yourself - and with the right friends by your side, PlanetSide 2 is an unforgettable experience.


from his list of potential nominees, a document filled with down-the-line conservatives that would dramatically shift the balance of the court to the right. Collins said an “outside group” should not be dictating whom the Senate considers; Murkowski said Trump has already kept his commitment to the list by elevating Gorsuch to the Supreme Court and should extend his search beyond that list.

Senate Majority Leader Mitch McConnell (R-Ky.) met privately with Murkowski about the Supreme Court on Thursday afternoon, though she declined to comment on the nature of the conversation.

GOP leaders are already advising Trump to draft a justice who is restrained in rhetoric and that the president try to appeal to moderates. Senate Majority Whip John Cornyn (R-Texas) said a nominee who stated to senators that heCheck out our new site Makeup Addiction

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I don't listen to dubstep. I listen to POST-DUBSTEP


owner, for change. After
     receiving the change, the Complainant turned around and saw
     Appellant approximately [twenty] feet away.       The Appellant
     pulled a gun from his waistband and frantically pointed the gun
                                                          -
     Johnny immediately fled to the back of the store and Khalil
     followed, leavingevidence and how he was prejudiced in that regard.               The

adverse ruling on the motion in limine was sufficient to preserve his

objection to the admissibility of this evidence for appellate review.           The

unrelated to the motion in limine.      For all of the aforementioned reasons,

Appellant is not entitled to relief.

      Judgment of sentence affirmed.

                                       - 17 -
J-A21011-14

Judgment Entered.

Joseph D.


grew from February to November 2016 ([Fig 2D](#pone.0165085.g002){ref-type="fig"}). We performed Pearson Product-Moment Correlation analyses to examine temporal correlations between the accumulative volumes of Zika-related search queries and the cumulative numbers of reported cases. The result indicated that the data on Zika-related GTs had statistically significant and positive correlations with the cumulative numbers of confirmed cases (R = 0.968, *p\<0*.*001*), suspected cases (R = 0.980, *p\<0*.*001*) and total cases (R = 0.988, *p\<0*.*001*) of ZIKV.

![Time series plot of the daily GTs volumes from 12 February to 9 November 2016 (Yearly EPI Week 6 to 45).](pone.0165085.g001){#pone.0165085.g001}

![Time series plots of the number of reported ZIKV confirmed cases (A), suspected cases (B), total cases (C) and the accumulated Google search volumes (D) during the ZVD epidemic from 12 February to 9 Novemberhis albums is called ‘Jihad’.

However, the 35-year-old rapper, born in the Channel port of Le Havre, has offered his condolences to the families of those killed in the Paris attacks. He says he is against violence and the jihad he is referring to is an individual, internal struggle.


in villages and towns not served by rail carriers, and to bulk and service stations located outside of the corporate limits of villages, towns, and cities in this state, and the commission was directed to annul its former order and issue an amended order and certificate limited as above outlined.
In appeals to the district court under the Administrative Agencies, Uniform Practice *29 Act, Chapter 28-32, RCND 1943, the court shall try and hear the appeal without a jury upon the record filed with the court and "After such hearing, the court shall affirm the decision of the agency unless it shall find that such decision or determination is not in accordance with law, or that it is in violation of the constitutional rights of the appellant, or thatcarrier, the commission shall take into consideration four factors1, existing travel upon the route of the carrier; 2, the increased cost of maintaining the highway concerned; 3, the effect on other essential forms of transportation; 4, existing transportation facilities in the territory for which a certificate is sought. The same section further provides that: "In case it appears from the evidence that the service furnished or that could be furnished by existing transportation facilities is reasonably adequate, the commission shall not grant such certificate." Upon the former appeal of this case, N.D., 33 N.W.2d 615, we directed that the case be returned to the Public Service Commission for explicit findings upon the matters required to be considered by the commission under Section 49-1814, RCND 1943. These findings have


now been made, and they, together with the evidence that was before the commission, are now before us on this appeal.
The railroads challenge the sufficiency of the evidence to support the findings of the commission upon the ground, among others, that the showing made by the applicant establishes that the service which he proposes to render is for the convenience of the supplying oil companies and their bulk station operators, rather than the convenience of the public. The bulk station operators and others who said they needed and would use the applicant's transport service are a part of the public and their business is such that they in turn serve the public generally. The bulk station operators stress the fact that the demand for their major products fluctuatesService Commission may permit motor carriers to enter into unrestricted competition with existing transportation facilities. Swartwout v. Ditsworth, N.D., 48 N.W.2d 22. No amendment was made of Section 49-1814, RCND 1943 which prohibits the granting of a certificate "In case it appears from the evidence that the service furnished or that could be furnished by existing transportation facilities is reasonably adequate,".
The railroads argue that at the most the applicant is entitled to a certificate authorizing him to haul to specific points where necessity for transportation has been proved and where the evidence shows the present transportation to be inadequate. The application under consideration does not seek authority to transport to specific points, but for general authority to operate from or to a territory or zone under the provisions


Q:

Double data type calculator C#

Hello I am fairly new to C# programming and I need some help with my calculator. I'm try to use double data members and method, but when I use it nothing happens. Could someone explain what I am doing wrong?
static void Main(string[] args)
    {
        Double FirstOperand;
        Double SecondOperand;
        Double Result;

        FirstOperand = Convert.ToDouble(Console.ReadLine());
        Console.Write("What is your first number?");
        SecondOperand = Convert.ToDouble(Console.ReadLine());
        Console.Write("What is your second number?");
     gradient centrifugation procedures ([@B21]; [@B7]). Synaptosomes retain functional properties such as membrane potential and depolarization-induced neurotransmitter release, making them key model systems for fundamental synaptic biology ([@B46]). However, studies of synaptosomes in bulk are limited by the purity of the preparations, which contain a mixture of synapse types (e.g., glutamatergic, GABAergic, etc.) as well as contaminating neuronal and glial membranes. In principle, high-throughput purification and analysis of single synaptosomes is a powerful tool for addressing the incredible heterogeneity of the billions of synapses in mammalian brains.

Flow cytometry employs a pressurized fluidic system to pass suspensions of cells or particles through an optical flow cell, where scattered light and fluorescence measurements are collected for each particle. Analysis of submicron particles on conventional flow cytometers faces a variety of limitations


S1 supernatant was further centrifuged at 10,000 × *g* (Eppendorf 5424R) for 20 min to obtain the crude synaptosome pellet (P2). P2 pellets were cryopreserved by resuspension in 4 mM HEPES/0.32 M sucrose buffer + 5% DMSO and slowly frozen to --80°C using an isopropanol freezing container. Frozen synaptosomes were used within two months. This protocol, when combined with rapid thawing at 37°C on the day of the experiment, has been shown to preserve synaptosome function and morphology ([@B14]; [@B6]). After thawing, all experiments were conducted with either PBS (137 mM NaCl, 2.7 mM KCl, 8 mM Na~2~HPO~4~, and 2 mM KH~2~PO~4~) or sucrose/EDTA/tris (SET) buffer (320 mM sucrose, 5 mM Tris, and 1 mM EDTA).

Flow cytometry instrumentation and setup {#s3C}
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All flow cytometry data acquisition was conducted usingheterogeneous mixture of free mitochondria, myelin, and membranous debris, P2 samples are enriched with synaptosomes and have been widely employed in flow cytometry studies ([@B18]; [@B11]; [@B35]; [@B37]). As previously described by [@B3], FM4-64 is a styryl dye with favorable properties for fluorescence-triggered detection of synaptosomes. FM4-64 is minimally fluorescent in aqueous media but becomes intensely fluorescent on partitioning into membranes ([@B44]), and its far-red emission is efficiently excited by a 488nm laser, which is required for triggering on our cytometers. As shown in [Figure 1*C*,*D*](#F1){ref-type="fig"}, FM triggering enabled highly sensitive detection of P2 samples compared to FSC triggering, with more than half of particles in the P2 sample below the FSC noise threshold on both cytometers. These results are consistent with the work of [@B2]; his Results


below ∼1000 particles/µL. A previous study on the Influx ([@B23]) showed that the trigger pulse baseline becomes continuously elevated at high event rates where coincidence is prominent, so we used a digital oscilloscope on the Influx to confirm that the trigger pulse remained at baseline under these conditions (data not shown).

Development of a multicolor fluorescence assay for false colocalization {#s4C}
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Although FM triggering and dilution should help to reduce coincident particle detection, another reported source of "false double-positive" events in submicron flow cytometry is the physical aggregation of multiple particles ([@B9]). Multiple microscopy studies have noted the presence of aggregated synaptosomes ([@B15]; [@B5]; [@B6]), but conventional flow cytometry does not provide a means to verify whether events truly represent single particles. We sought to design a fluorescence-based flow cytometrybearing the other calcein dye. We confirmed this by sonicating a P2 sample truly double-labeled with both calcein dyes and adding an unlabeled P2 sample to the sonicated solution using the exact same experimental workflow. As shown in Extended Data [Figure 3-1*B*](#fig3-1){ref-type="supplementary-material"}, no calcein AM-positive or calcein red-positive events were detected. This demonstrates that even after complete membrane disruption to liberate the entire dye content of one sample, we do not observe measurable transfer to an unlabeled sample after washing and mixing.

Aggregation, but not coincidence, causes false double-positive events in P2 samples {#s4D}
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With our multicolor fluorescence assay in hand, we turned toward distinguishing between coincidence and aggregation. Similar to previous studies ([@B28]), we used mixtures of green- and red-fluorescent 500-nm PS beads to model coincidence. We repeated the


1, *F* = 8.00, *p* = 0.006), but not for triple-positive events (Df = 1, *F* = 1.91, *p* = 0.17). None of the buffer × FSC gate interactions were significant. Thus, although PBS-SET samples did display reduced aggregation, the effect was modest, especially for triple-positive events. Similar to the percentage of immunopositive events within each FSC gate, the frequency of false co-localization increases with FSC. To further illustrate this point, we calculated the percentage of immunopositive events for each antigen that were single-, double-, or triple-positive within each FSC gate (Extended Data [Fig. 7-2](#fig7-2){ref-type="supplementary-material"}). In the FSC noise region we found that ∼80% of VGAT+, ∼75% of VGLUT1+, and ∼63% of VMAT2+ events were single-positive. Strikingly, in the highest FSC gate, the single-positive percentage was only ∼12%preparations do not behave similarly to cells in these experiments. Determining the extent of single-particle detection in submicron flow cytometry experiments is a challenging task. Image cytometry, which combines confocal microscopy with the fluidics of a cytometer, is powerful in this regard since images of each event can be manually examined after acquisition. However, these instruments require extensive optimization and are not widely available to all labs. The fluorescent labeling and mixing assay we describe here can be implemented on most conventional flow cytometers and should be broadly useful to the microparticle flow cytometry community.

Distinguishing between coincidence and aggregation {#s5D}
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As we were unable to reduce the frequency of false double-positive events with extensive dilution and FM triggering of our P2 mixtures ([Fig. 4*C*,*D*](#F4){ref-type="fig"}), we began to suspect aggregation