left with enough?” But there’s no problem. There’s no problem at all.

J.C., why do you feel you need full-time legal representation?

SCHENCK: That goes under attorney-client, but I wouldn’t say I am full-time.

J.C.: I wish quite frankly I never had him. I have been so used and exploited. The only thing that matters is one thing: That is him [Stan] being okay, and happy… All that mattered was my mother, until she passed. That is all in my life that matters. And these mothers… [She starts crying]... They hate me, and they don’t feel that I deserve it, or that I’ve earned it…

Who is “they?”

J.C.: We’ve got a few of them. Four of them. But, they’re not going away. When this guy Brad [Brad Herman, Stan’s former business manager]Happy that I took the right path.

J.C.: You always do, pop. It was just the people around you. It was never you. You were always the good guy, and there were just creeps around you, and it was this town. Never you.

STAN: I learned later on in life, you need advisors if you’re making any money at all. I did everything myself. The first years of my career when I wrote Super Rabbit [an early cartoon character he created], and when I wrote all those characters, and I wrote the Hulk—I handled everything. I paid all the bills, I did all the bookkeeping, I handled everything. But then, a little money started coming in, and I realized I needed help. And I needed people I could trust. And


one instruction to subsequent instructions through registers. To ensure program correctness, registers are renamed and instructions wait in reservation stations until their input operands are generated, at which time they are issued to the appropriate functional units for execution. The register renamer, reservation stations, and related mechanisms link instructions having dependencies together so that a dependent instruction is not executed before the instruction on which it depends. Accordingly, such processors are limited by in-order fetch and decode.
When the instruction from the instruction cache misses or a branch is mis-predicted, the processors have either to wait until the instruction block is fetched from the higher level cache or memory, or until the mis-predicted branch is resolved, and the execution of the false path is reset.
The result of such behaviori.e., the “basic defect,” in both CB and CF is the failure to clear mucus from airway surfaces. The failure to clear mucus reflects an imbalance between the amount of liquid and mucin on airway surfaces. This “airway surface liquid” (ASL) is primarily composed of salt and water in proportions similar to plasma (i.e., isotonic). Mucin macromolecules organize into a well defined “mucus layer” which normally traps inhaled bacteria and is transported out of the lung via the actions of cilia which beat in a watery, low viscosity solution termed the “periciliary liquid” (PCL). In the disease state, there is an imbalance in the quantities of mucus as ASL on airway surfaces. This results in a relative reduction in ASL which leads to mucus concentration, reduction in the


in the placebo or ertugliflozin groups (Pearson correlation coefficient p values \> 0.05; Fig. [4](#Fig4){ref-type="fig"}a). Across all treatment groups, there was a significant correlation between the change from baseline in SBP and body weight at Week 26 (Pearson correlation coefficient p values \< 0.05; Fig. [4](#Fig4){ref-type="fig"}b).Fig. 4Correlation between systolic blood pressure (SBP) and glycated hemoglobin (HbA1c) and body weight. Change from baseline in SBP at Week 26 versus change from baseline in HbA1c at Week 26 (**a**) and change from baseline in body weight at Week 26 (**b**). *HbA1c* glycated hemoglobin

Both ertugliflozin 5 mg and 15 mg resulted in a greater reduction from baseline in DBP and pulse rate compared with placebo at Week 26 (Fig. [5](#Fig5){ref-type="fig"}a, b).Fig. 5Change from baseline in sitting diastolic blood pressure (DBP) and pulse rate at Week 26. Change from baseline in sitting DBP at\[[@CR11]--[@CR13], [@CR37]\]. Alternative pathways may account for the BP-lowering effects reported with ertugliflozin and other SGLT2 inhibitors, such as reductions in arterial stiffness and weight loss \[[@CR10], [@CR38]\]. In keeping with this, changes from baseline in SBP did correlate with changes from baseline in body weight in both placebo and ertugliflozin groups in this analysis. Other studies have also shown that reductions in body weight were associated with reductions in arterial stiffness and BP \[[@CR38]\]. Treatment with SGLT2 inhibitors can alter body composition by reducing total body fat with minimal changes to lean muscle; reduction in body fat has been suggested as an additional mechanism by which SGLT2 inhibitors lower BP \[[@CR36]\]. However, a rodent model of an SGLT2 inhibitor (empagliflozin) reported that reductions in arterial stiffness were


system is disclosed in DE-PS No. 32 27 776.
One known valve device is configured as four-part valve with three user connections, which should be fed pressure medium in a special way from a pressure medium source. With the known valve device, an arrester valve closing in the direction of the reservoir port is connected to a passage connecting the pressure port and the reservoir port. One of the users is attached in the passage connecting the pressure port with the arrester valve. An additional arrester valve, opening in the direction of the user, is arranged in this passage before this user. Such system is disclosed in DE-OS No. 29 35 949.Locus of control, machiavellianism, and managerial job performance.
In this study, we examined the moderating effect of locus of control on the relationship between Machiavellianism and job performance of store managers in a retail setting. Our results indicated a significant moderating effect for managers who perceive that they have an external control orientation but not for managers with an internal control orientation.


may decrease the biotransformation of GTN to GDNs and nitric oxide, thereby resulting in less dilation of blood vessels. Furthermore, the males in the hypothermic CPB group had significantly greater urinary concentrations of 1,3-GDN and 1,2-GDN than the females (P < 0.05), and the normothermic CPB males had a significantly greater urinary concentration of 1,2-GDN than the females in that group. The normothermic CPB males also had significantly higher plasma concentration of GTN at two time points, and 1,3-GDN at one time point, than the females. These data suggest that there may be a gender difference in GTN biotransformation.quantum computational techniques.

Grover’s famous quantum algorithm [@grover96] for fast unstructured search can be applied to the naïve classical algorithm to achieve a runtime of $O(\sqrt{n!})$, up to polynomial terms in $n$. However, the best classical algorithms are already substantially faster than this. For many years, the algorithm with the best proven worst-case bounds for the general TSP was the Held-Karp algorithm [@held1962], which runs in $O(n^22^n)$ time and uses $O(n2^n)$ space. This algorithm uses the fact that for any shortest path, any subpath visiting a subset of vertices on that path must be the shortest path for visiting those vertices. Held and Karp used this to solve the TSP by computing the length of the optimal route for starting at vertex $1$, visiting every vertex in a set $S \subseteq


general simulated or quantum annealing, but quantum annealing could outperform simulated annealing alone. However, they noted that simulated annealing could perform better than in their analysis if combined with local search heuristics [@martin1996].

Chen et al. [@chen11] experimentally demonstrated a quantum annealing algorithm for the TSP. Their demonstration used a nuclear-magnetic-resonance quantum simulator to solve the problem for a graph with 4 vertices.

Organisation
------------

We start by introducing the main technique we use, backtracking, and comparing it with amplitude amplification. Then, in Section \[sec:bd\], we describe how this technique can be used to accelerate classical algorithms of Xiao and Nagamochi for graphs of degree at most 4 [@xiao2016degree3; @xiao2016degree4]. In Section \[sec:higher-bound\], we extend this approach to graphs of degree at most 6.

Backtracking algorithms for the TSP {#sec:backtrack}
===================================

Many of the most efficient classical algorithmspartial assignments, backtracking algorithms have two components. The first is a predicate, $P:\mathcal{D} \rightarrow \{\text{true}, \text{false}, \text{indeterminate}\}$, which takes a partial assignment and returns true if this assignment will definitely result in the constraints being satisfied regardless of how everything else is assigned, false if the assignment will definitely result in the constraints being unsatisfied, and indeterminate if we do not yet know. The second is a heuristic, $h:\mathcal{D} \rightarrow \{1,\dots,v\}$, which takes a partial assignment and returns the next variable to assign.

The following simple recursive classical algorithm takes advantage of $P$ and $h$ to solve a constraint satisfaction problem. We take as input a partial assignment (initially, the empty assignment). We run $P$ on this partial assignment; if the result is true then we return the partial


searching for the solution via amplitude amplification could require up to $O^*(2^{n/4})$ time in the worst case. To yield a better runtime, we must take more of an advantage of the structure of our search space to avoid instances which will definitely not succeed.

The same issue with amplitude amplification applies to other classical algorithms for the TSP which are based on backtracking [@xiao2016degree3; @xiao2016degree4]. In the case of the Xiao-Nagamochi algorithm for degree-3 graphs, although the overall runtime bound proven for the problem means that the number of vertices in the tree is $O(2^{3n/10})$, several of the branching vectors used in their analysis have branches that reduce the problem size by less than $10/3$, leading to a branch in the tree that could be more than $3n/10$ levels deep.

=\[draw,shape=circle,innerof degree $5$ into one vertex of degree $3$ and another of degree $4$ connected by a forced edge. These ten ways of splitting the vertex are shown in Fig. \[fig:degree-5\] for a vertex incident to edges $a,b,c,d,e$. Without loss of generality, let $a$ and $b$ be the two edges which are part of the Hamiltonian cycle. In order for $a$ and $b$ to also be part of the Hamiltonian cycle in the degree-4 graph produced, $a$ and $b$ cannot be adjacent to one another. Looking at Fig. \[fig:degree-5\], the split is successful in six of the ten ways of splitting the vertex.

If there are $f$ vertices of degree $5$, then there are $10^f$ possible ways of splitting all such vertices, of which $6^f$ will give the correct solution to


the TRANSFAC library of positional weight matrices (PWMs). Relatively few matches between the motifs and the TF matrices were found. Out of 12000 motifs reported at the previous step as being overrepresented in CNS versus the three different backgrounds, we have identified just 20 motifs that match TF matrices with E-values lower than 0.001 and satisfy factor class-specific cut-offs (Table [4](#T4){ref-type="table"}). The majority of these matches involved matrices for the factors of \"Forkhead DNA-binding domain\", especially of the FOX family, which were repeatedly found over two rather different backgrounds: of non-CNSs and randomized sequences. Among the motifs found over the background of near-promoter sequences, there was only one that matched a PWM.

######

Motifs found matching transcription factor PWMs from TRANSFAC

  **Accession**      positions. Equation (3) is a symmetrized relative entropy or Kullback-Leibler (KL) divergence. Relative entropy was used previously in applications for classification of protein as well as nucleotide patterns \[[@B36],[@B37]\]. The m2transfac scoring system combines the advantages of both measures. The KL divergence directly assesses the difference of two distributions and therefore increases specificity for similar distributions, but makes no distinction on the basis of their conservation, which is however a property of the column score.

The m2transfac output provides E-values, the number of alignments with greater or equal score expected from searching a database with 1000 matrices. These are derived for each TRANSFAC PWM from score distribution estimates based on large-scale searches of a random matrix library. Furthermore, we apply the transcription factor classification that was developed in our


group \[[@B38],[@B39]\] to gather matrices according to DNA-binding domain classes of their binding factors and derive factor class-specific score thresholds. We define 57 matrix groups, 15 of which comprise matrices which cannot be associated with a particular factor class, e.g. the barbiturate-inducible element, or whose binding factors are so far not assigned to a protein-structural class. Some matrices occur in more than one class if TFs of different classes are annotated as binding factors, or binding factors possess multiple DNA-binding domain types. For each PWM, score thresholds are defined at three levels of stringency above the score of the first observed false positive in a search of the TRANSFAC database.

Authors\' contributions
=======================

SM designed and carried out the computational experiments; PS developed the program and analyzed TRANSFAC PWMs, A KelValidation of a rapid, automated method for the measurement of ethylene glycol in human plasma.
Background Ethylene glycol is a highly toxic compound found in various household products. Cases of poisoning are rare but may be fatal unless diagnosed and treated promptly. Early recognition of poisoning is critical for the management and recovery of patients. Indirect testing is not specific for the presence of ethylene glycol. Therefore, urgent and accurate measurement should be sought if ingestion is suspected in order to determine the need for treatment with an antidote. Here, we present the validation of an automated assay for measurement of ethylene glycol on an Abbott Architect using a commercially available kit (Catachem). Methods Analytical parameters of imprecision, linearity, stability and bias were determined using spiked human plasma samples


on average 25, 28, 30, and 38 amide protons, respectively. After prolonged incubation with D2O for 24 hours, bovine and porcine insulins exchanged 31 protons, whereas r-Human and LysPro insulins exchanged 34 and 43 amide protons, respectively. The differences in H/D exchange are protein signatures that relate to differences in conformation and folding. Extent of exchange distinguishes among the insulin types and assures the consistency of batch preparations for a given insulin.certain there are plenty of substitutes for everything I have described here. Nor do I consider this a one-size-fits all answer either. But there is something unique about the gaming experience that is immeasurably helpful to the issues at hand. Its immersion is most pertinent. And for better or worse, it keeps me sane.

Above else, it requires clearing your head through whatever means that takes. I would suggest eating well, exercising regularly and switching off your phone every once in a while. But it's not my place to say how one should combat these things. To this day, I still struggle with my anxiety and underlying depression when it strikes. All we can really do is open a discussion and appease the moments we falter. However, note that


    description
       " This module contains a collection of YANG definitions for
         monitoring memory usage of processes in a Network Element.";

    reference "TODO";

    revision 2015-04-09 {
        description "Proposed";
    }

    container cfm-statistics {
        config false;
        description
          "Data nodes for CFM Statistics.";

        list mep {
            key "domain-nameKonami recently announced that they’re working on the latest of the sniper arcade series, with Silent Scope: Bone Eater. They also just shared a look at the game’s opening video featuring its new anime-style protagonists.

While the game is similar to the ’90s shooter with zoom-in sniping features, it also has a networking feature that lets four machines link up. Also, the soundtrack definitely has some sort of Metal Gear Solid vibe going for it. Well, except that it’s more upbeat.

Silent Scope: Bone Eater is currently in development for arcades.


Obama Said to Choose Raskin for Deputy Treasury Secretary

Federal Reserve Governor Sarah Bloom Raskin was nominated to the Fed in March of 2010. Photographer: Andrew Harrer/Bloomberg

July 31 (Bloomberg) -- President Barack Obama plans to name
Federal Reserve Governor Sarah Bloom Raskin as deputy Treasury
Secretary, making her the highest-ranking woman in the history
of the Treasury department, according to two people familiar
with the matter.

Raskin, 52, has been vetted for the position and Obama
plans to nominate her in the coming weeks, according to the
people, who asked for anonymity to discuss the personnel
decision before an announcement. Treasury Secretary Jacob J. Lew
has been told of the choice, according to one of the people.

Prior to serving as Maryland’s top financial regulator from
2007 to 2010, Raskin was a managing director at Promontory
Financial Group, which advises banks.Analysis of 29 cases of pancreatic pseudocyst treated surgically.
Twenty-nine cases of pancreatic pseudocyst requiring operative management were reviewed to determine the method of diagnosis and to analyse the results of internal and external drainage. Pain and the presence of an intra-abdominal mass were the two most common clinical features in the 29 patients. Serum amylase values were elevated in 50%. Diagnosis was confirmed by barium contrast roentgenography and abdominal ultrasonography in 60% of cases. Endoscopic retrograde cholangiopancreatography was a valuable diagnotic technique in four problem cases. The most common form of surgical treatment was internal drainage of the pseudocyst (18 patients). Th mortality resulting from internal drainage was 6% and there was an overall complication rate of 44%. External drainage was carried out in seven patients (six required


surprising that in Fig. \[fig5\] the theoretical curve at small wave-vectors is above the experimental one.

In the inset of Fig. \[fig6\] we show the compressibility of our system as calculated from Eq. (\[eq4\]). We see that also this quantity has a maximum at a temperature which corresponds to the location of the density anomaly of the system, i.e. for this model at around 4700 K. No experimental data for $\kappa_T$ in this temperature range are known to us. However, Fraser [@fraser68] reports for $T=1673$ K a compressibility around $2.7\cdot 10^{-5}$ GPa$^{-1}$. If we extrapolate the (equilibrium) compressibility data in Fig. \[fig6\] to $T=1673$ K, we obtain a $\kappa_T$ at around $1.35\cdot 10^{-5}$ GPa$^{-1}$ which is a factor of two smaller than the one given by Fraser. Thus we have evidence that the BKS model is a bit too stiff.we see that for temperatures around 2800 K such an extrapolation underestimates the viscosity of real silica, as measured by Urbain [*et al.*]{} [@urbain82] (open circles), by about a factor of 10. Thus we find that the BKS model underestimates the viscosity of real silica but that the error lies in the prefactor and not in the activation energy. (We also mention that there seems to be an uncertainty of the experimental value of the prefactor of about a factor of two [@mazurin83], thus it might be that the actual discrepancy between our simulation and reality is less than just stated.) We also mention that if the Arrhenius law found for our low temperature data is used for estimating the temperature at which the viscosity of our system reaches the value


behavior of the system crosses over from one similar to an activated process to one which is, potentially, described well by the ideal version of MCT. On the other hand, the ideal version of the theory predicts a power-law divergence to infinity of $D$ and $\eta$ at $T_c$, which in our case is at 3330 K, while Figs. \[fig8\] and \[fig10\] show that this is not the case. Thus the need for the extended version of MCT is evident. Further support for a change of the transport mechanisms is obtained by investigating the temperature dependence of the life time of a bond between a silicon and an oxygen atom. From Fig. \[fig2\]b we see that even at the highest temperature there is a well defined minimum between the first and secondlong enough to allow to observe the diffusive regime in the mean squared displacement and in Refs. [@horbach98a; @horbach99] we show that also the structural correlation functions, such as the intermediate scattering functions $F_s(q,t)$ and $F(q,t)$ at the FSDP [@boon_yip80], decay to zero within the time span of our simulation. Hence we conclude that in order to become diffusive, or for the decay of the mentioned structural correlation functions, it is not necessary that all of the bonds between silicon and oxygen break[^2].

From the figure one also sees that the shape of the curves does not seem to depend on temperature. This can be checked by plotting $P_B(t)$ versus $t/\tau_B$, where the “life time”$\tau_B(T)$ is defined by requiring that $P_B(\tau_B)=e^{-1}$. In the inset of Fig. \[fig11\] we show this type of


that the correlation hole that is observed at time zero is filled up not only by a continuous influx from other oxygen atoms but to some extent also by particles which hop directly into the position of the oxygen atom which was there at time zero. This type of dynamics is not observed in simple liquids at high temperatures [@ss_sim; @roux89; @kob_lj] and is thus probably attributable to the fact that silica forms a well defined network even at high temperatures thus making the correlation hole relatively stable and hence permitting that a new oxygen atom can jump into it. We emphasize, however, that at these high temperatures this jump mechanism is not the dominant transport mechanism, since the self part of the van Hove function does not showand B. Farago, Z. Phys. B [**83**]{}, 175 (1991); M. Kiebel, E. Bartsch, O. Debus, F. Fujara, W. Petry, and H. Sillescu, Phys. Rev. B [**45**]{}, 10301 (1992); A. Tölle, H. Schober, J. Wuttke, and F. Fujara, Phys. Rev. E [**56**]{}, 809 (1997); H. Z. Cummins, G. Li, W. Du, Y. H. Hwang, and G. Q. Shen, Prog. Theor. Phys. Suppl. [**126**]{}, 21 (1997); A. Tölle, J. Wuttke, H. Schober, O. G. Randl, and F. Fujara, Eur. Phys. J. B [**5**]{}, 231 (1998).

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Eds.: K. L. Ngai and G. B. Wright (US Dept. Commerce, Springfield, 1985).

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A. Wischnewski, U. Buchenau, A. J. Dianoux, W. A. Kamitakahara, and J. L. Zarestky, Phys. Rev. B [**57**]{}, 2663 (1998).

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B. Bernu, J.-P. Hansen, Y. Hiwatari, and G. Pastore, Phys. Rev. A [**36**]{}, 4891 (1987); H. Miyagawa, Y. Hiwatari, B. Bernu, and J.-P. Hansen, J. Chem. Phys. [**88**]{}, 3879 (1988); J.-L. Barrat, J.-N. Roux, and J.-P. Hansen, Chem. Phys. [**149**]{}, 197 (1990); H. Miyagawa and Y. Hiwatari, Phys. Rev. A [**44**]{}, 8278 (1991).

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P. Gallo, F. Sciortino, P. Tartaglia and S.-H. Chen, Phys. Rev. Lett. [**76**]{}, 2730 (1996); S.-H. Chen, P. Gallo, F. Sciortino, and P. Tartaglia, Phys. Rev. E [**56**]{}, 4231 (1997); F. Sciortino, L. Fabbian, S.-H. Chen, and P. Tartaglia, Phys. Rev. E [**56**]{}, 5397 (1997).

M. Hemmati and C. A. Angell, in [*Physics meets Geology*]{}, Eds.: H. Aoki and R. Hemley (Cambridge Univ. Press, Cambridge, 1998).

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K. Vollmayr and


published.

S. P. Das and G. F. Mazenko, Phys. Rev. A [**34**]{}, 2265 (1986); W. Götze and L. Sjögren, Z. Phys. B [**65**]{}, 415 (1987); M. Fuchs, W. Götze, S. Hildebrand, and A. Latz, J. Phys.: Condens. Matter [**4**]{}, 7709 (1992).

T. Gleim, W. Kob, and K. Binder, (unpublished).

J.-L. Barrat, J. Badro, and P. Gillet, Mol. Sim. [**20**]{}, 17 (1997).

J.P. Boon and S. Yip, [*Molecular Hydrodynamics*]{} (Dover, New York, 1980).

M. P. Allen, D. Brown, and A. J. Masters, Phys. Rev. E [**49**]{}, 2488 (1994);

M. P. Allen, [*ibid.*]{} [**50**]{}, 3277 (1994).

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O. V. Mazurin, M. V. Streltsina, and T. P. Shvaiko-Shvaikovskaya, [*Handbook of Glass Data, Part A: Silica GlassCarotid Plaque Vulnerability Assessment Using Ultrasound Elastography and Echogenicity Analysis.
The purpose of this study was to evaluate ultrasound elastography and echogenicity analysis to discriminate between carotid plaques in patients with symptomatic internal carotid artery (ICA) stenosis versus patients with asymptomatic stenosis. Patients with symptomatic and asymptomatic ICA stenosis of more than 50% were recruited for the study. After both carotid arteries were scanned, plaque translation and elastography and echogenicity features were assessed. Parameters of index stenosis (i.e., symptomatic or more severe stenosis) were compared between populations. For further validation, parameters of index stenosis were also compared with those of the contralateral artery for segments with plaque. Segments without plaque on the index side were also evaluated between populations. ROC curve analyses were performed using a cross-validation method with


analysis of variance and Tukey's honest significant difference test. Results: (1) The levels of serum ALT, AST, CG, CK, CK-MB, BUN, and creatinine, pulmonary W/D ratio, as well as MPO activity of rats in sepsis group were significantly higher than those in sham injury group and VNS group (P<0.01) and were significantly lower than those in VGX group (P<0.01). (2) The proliferative activity of CD4(+) T lymphocytes of rats in sepsis group was 0.93±0.03, which was significantly lower than 1.54±0.07 of rats in sham injury group (P<0.01). The proliferative activity of CD4(+) T lymphocytes of rats in VNS group was 1.15±0.15, which was significantly higher than that of rats in sepsis group (P<0.01). The proliferative activity of CD4(+) T lymphocytes of rats in VGX group was 0.75±0.06, whichHey Everyone! I am here to announce a giveaway I am having on Friday March 31st. I will be giving away an Overwatch Funko Pop. It will be a Widowmaker figure, and if I hit over 50 followers by then I will also be giving away a Green ECCC Exclusive Pharah Funko Pop. Shipping is Free worldwide, you must be in my channel and in the chat around 5-6 PM Eastern Time to qualify for the giveaway!

Hey Everyone! I am here to announce a giveaway I am having on Friday March 31st. I will be giving away an Overwatch Funko Pop. It will be a Widowmaker figure, and if I hit over 50 followers by then I will also be giving away a Green ECCC Exclusive Pharah Funko


                             (N.D. of Okla.)
 EDWARD EVANS,                                    (D.C. No. CV-95-940-JHP)

              Respondent-Appellee.

           ORDER DENYING CERTIFICATE OF APPEALABILITY *

Before TACHA, TYMKOVICH, and GORSUCH, Circuit Judges. **

      Harold D. Hornsby, a state prisoner proceeding pro se, 1 has spent the last

thirteen-and-a-halfyears in federal court attempting to invalidate his state-law

convictions for larceny from a person, larceny of merchandise, robbery by fear,

and robbery by firearms. After several years of litigation, the district court

      *
         This order is not binding precedent except under the doctrines of law of
the case, res judicata and collateral estoppel. It may be cited, however, for its
persuasive value consistent with Fed. R. App. P. 32.1 and 10th Cir. R. 32.1.
      **
         After examining the briefs and the appellate record, this three-judge
panel has determined unanimously that oral argument would not be of material
assistance in the determination of this appeal. See Fed. R.


Hat Ambassador: Blossom or Pharrell?

No question. Duh.

Which Celebrity Gave the Best Dream Advice: ALF or Hugh Hefner?

YouTube

Where Have You Been, Jenna Von Oÿ?

Seriously though, where?

And Why Wasn't Ted Wass Invited?!

As a director he's done more work than all of these folks combined. AND he was Blossom's dad! You never leave out dad.directory entry
 * @adding: indicates caller is adding a key to the TNC
 *
 * This is a "fallible" version of the 'resolve_collision()' function which
 * does not panic if one of the nodes referred to by TNC does not exist on the
 * media. This may happen when replaying the journal if a deleted node was
 * Garbage-collected and the commit was not done. A branch that refers to a node
 * that is not present is called a dangling branch. The following are the return
 * codes for this function:
 *  o if @nm was found, %1 is returned and @zn and @n are set to the found
 *    branch;
 *  o if we are @adding and @nm was not found,


found, we will assume it is obsolete and may overwrite
	 * it. Then if there is an unclean unmount, we will start using the
	 * old index which will be broken.
	 *
	 * So we first mark znodes that have insertions at slot zero, and then
	 * if they are split we add their lnum/offs to the old_idx tree.
	 */
	if (n == 0)
		znode->alt = 1;
}

/**
 * tnc_insert - insert a node into TNC.
 * @c: UBIFS file-system description object
 * @znode: znode to insert into
 * @zbr: branch to insert
 * @n: slot number to insert new zbranch to
 *
 * This function inserts a new node described by @zbr into znode @znode. If
 * znode does not have a free slot for new zbranch, it is split.- add a node to TNC.
 * @c: UBIFS file-system description object
 * @key: key to add
 * @lnum: LEB number of node
 * @offs: node offset
 * @len: node length
 *
 * This function adds a node with key @key to TNC. The node may be new or it may
 * obsolete some existing one. Returns %0 on success or negative error code on
 * failure.
 */
int ubifs_tnc_add(struct ubifs_info *c, const union ubifs_key *key, int lnum,
		  int offs, int len)
{
	int found, n, err = 0;
	struct ubifs_znode *znode;

	mutex_lock(&c->tnc_mutex);
	dbg_tnck(key, "%d:%d, len %d, key ", lnum, offs, len);
	found = lookup_level0_dirty(c, key, &znode, &n);
	if (!found) {
		struct ubifs_zbranch zbr;

		zbr.znode = NULL;
		zbr.lnum = lnum;
		zbr.offs = offs;
		zbr.len = len;
		key_copy(c, key, &zbr.key);
		err = tnc_insert(c, znode, &zbr, n + 1);
	} else if (found == 1)


znode);
					if (IS_ERR(znode)) {
						err = PTR_ERR(znode);
						goto out_unlock;
					}
				}
				zbr = &znode->zbranch[n];
				lnc_free(zbr);
				err = ubifs_add_dirt(c, zbr->lnum,
						     zbr->len);
				if (err)
					goto out_unlock;
				zbr->lnum = lnum;
				zbr->offs = offs;
				zbr->len = len;
			}
		}
	}

	if (!found)
		err = ubifs_add_dirt(c, lnum, len);

	if (!err)
		err = dbg_check_tnc(c, 0);

out_unlock:
	mutex_unlock(&c->tnc_mutex);
	return err;
}

/**
 * ubifs_tnc_add_nm - add a "hashed" node to TNC.
 * @c: UBIFS file-system description object
 * @key: key to add
 * @lnum: LEB number of node
 * @offs: node offset
 * @len: node length
 * @nm: node name
 *
 * This is the same as 'ubifs_tnc_add()' but it should be used with keys which
 * may have collisions, like directory entry keys.
 */
int ubifs_tnc_add_nm(struct ubifs_info *c, const union ubifs_key *key,
		     int lnum, int offs, int len, const struct qstr *nm)
{
	int found, n, err = 0;
	struct ubifs_znode *znode;

	mutex_lock(&c->tnc_mutex);
	dbg_tnck(key, "LEB %d:%d, name.name = NULL };

	dbg_tnc("ino %lu", (unsigned long)inum);

	/*
	 * Walk all extended attribute entries and remove them together with
	 * corresponding extended attribute inodes.
	 */
	lowest_xent_key(c, &key1, inum);
	while (1) {
		ino_t xattr_inum;
		int err;

		xent = ubifs_tnc_next_ent(c, &key1, &nm);
		if (IS_ERR(xent)) {
			err = PTR_ERR(xent);
			if (err == -ENOENT)
				break;
			return err;
		}

		xattr_inum = le64_to_cpu(xent->inum);
		dbg_tnc("xent '%s', ino %lu", xent->name,
			(unsigned long)xattr_inum);

		nm.name = xent->name;
		nm.len = le16_to_cpu(xent->nlen);
		err = ubifs_tnc_remove_nm(c, &key1, &nm);
		if (err) {
			kfree(xent);
			return err;
		}

		lowest_ino_key(c, &key1, xattr_inum);
		highest_ino_key(c, &key2, xattr_inum);
		err = ubifs_tnc_remove_range(c, &key1, &key2);
		if (err) {
			kfree(xent);
			return err;
		}

		kfree(pxent);
		pxent = xent;
		key_read(c, &xent->key, &key1);
	}

	kfree(pxent);
	lowest_ino_key(c, &key1, inum);
	highest_ino_key(c, &key2, inum);

	return ubifs_tnc_remove_range(c, &key1, &key2);
}

/**
 * ubifs_tnc_next_ent - walk directory or extended attribute entries.
 * @c: UBIFS file-system description object
 * @key: key of last entry
 * @nm: name of last entry found or %NULL
 *
 * This function finds and reads the next directory or extended attribute entry
 * after


- 1;

		/* Go up until we can go left */
		znode = znode->parent;
		if (!znode)
			return NULL;
		if (n >= 0) {
			/* Now go down the rightmost branch to 'level' */
			znode = get_znode(c, znode, n);
			if (IS_ERR(znode))
				return znode;
			while (znode->level != level) {
				n = znode->child_cnt - 1;
				znode = get_znode(c, znode, n);
				if (IS_ERR(znode))
					return znode;
			}
			break;
		}
	}
	return znode;
}

/**
 * right_znode - get the znode to the right.
 * @c: UBIFS file-system description object
 * @znode: znode
 *
 * This function returns a pointer to the znode to the right of @znode or NULL
 * if there is not one. A negative error code is returned on failure.
 */
static struct ubifs_znode *right_znode(struct ubifs_info *c,
				       struct ubifs_znode *znode)
{
	int level = znode->level;

	while (1) {
		int n = znode->iip + 1;

		/* Go up until we can gois correct and it does
 * not have any pages beyond @size. Returns zero if the inode is OK, %-EINVAL
 * if it has a data page beyond @size, and other negative error code in case of
 * other errors.
 */
int dbg_check_inode_size(struct ubifs_info *c, const struct inode *inode,
			 loff_t size)
{
	int err, n;
	union ubifs_key from_key, to_key, *key;
	struct ubifs_znode *znode;
	unsigned int block;

	if (!S_ISREG(inode->i_mode))
		return 0;
	if (!dbg_is_chk_gen(c))
		return 0;

	block = (size + UBIFS_BLOCK_SIZE - 1) >> UBIFS_BLOCK_SHIFT;
	data_key_init(c, &from_key, inode->i_ino, block);
	highest_data_key(c, &to_key, inode->i_ino);

	mutex_lock(&c->tnc_mutex);
	err = ubifs_lookup_level0(c, &from_key, &znode, &n);
	if (err < 0)
		goto out_unlock;

	if (err) {
		key = &from_key;
		goto out_dump;
	}

	err = tnc_next(c, &znode, &n);
	if (err == -ENOENT) {
		err = 0;
		goto out_unlock;
	}
	if (err < 0)
		goto out_unlock;

	ubifs_assert(err == 0);
	key = &znode->zbranch[n].key;
	if (!key_in_range(c, key, &from_key, &to_key))
		goto out_unlock;

out_dump:
	block = key_block(c, key);
	ubifs_err(c, "inode %lu has size %lld, but there are data at


Hughes PW, Soppe WJJ, Albani MC. Seed traits are pleiotropically regulated by the flowering time gene *PERPETUAL FLOWERING 1* (*PEP1*) in the perennial *Arabis alpina*. Mol Ecol. 2019;28:1183--1201. 10.1111/mec.15034 30712274

1. INTRODUCTION {#mec15034-sec-0001}
===============

Plant life cycles are characterized by discrete phase transitions, such as the initiation of reproduction and the germination of seeds. The timing of age‐dependent transitions and their coordination with environmental cues strongly determines fitness (Bradford, [2005](#mec15034-bib-0011){ref-type="ref"}; Pianka & Parker, [1975](#mec15034-bib-0058){ref-type="ref"}; Takada, [1995](#mec15034-bib-0071){ref-type="ref"}). Both the timing of seed germination and flowering have evolved in response to predictable cues, such as seasonal thresholds of day length and temperature (Fenner, [1998](#mec15034-bib-0023){ref-type="ref"}; Imaizumi & Kay, [2006](#mec15034-bib-0036){ref-type="ref"}; Roff, [1996](#mec15034-bib-0061){ref-type="ref"}). The identification of genes regulating phenology is an important ongoing task in plant biology. However, the roles that genetic elements play in regulatingfour technical replicates for each time point tested. For each assay, a sample of 30--80 sterilized seeds was placed on moistened filter paper in 5cm Petri plates and germinated without stratification in a climate chamber programmed for a 25°C:20°C day:night temperature regime with a 12 hr:12 hr day:night photoperiod cycle. Photographs of the plate were taken seven days after the start of germination, and seed counts were performed in triplicate from these photos. The number of days of dry storage (i.e., after‐ripening) required for 50% germination (DSDS50) was computed by modelling time to germination using a GLM with a logit link (see: Hurtado et al., [2012](#mec15034-bib-0035){ref-type="ref"}), and the DSDS50 was the interpolated point at which the germination rate of the seed sample was 50% (He et al., [2014](#mec15034-bib-0027){ref-type="ref"}; Hurtado et al.,


accessions tested, using a method previously described (Nagel et al., [2016](#mec15034-bib-0053){ref-type="ref"}). All assays were performed using four to six independent biological replicates for each accession; six independent biological replicates were used for Paj and the *pep1‐1* mutant, and four for all other accessions. Each biological replicate was assayed by four technical replicates at each time point.

To assess differences in seed sensitivity to exogenous plant hormones, we conducted a series of seed hormone sensitivity trials for assessing seeds from all genotypes and experimental conditions. We conducted a hormone sensitivity trial on seeds collected just after harvest for gibberellic acid (GA4+7), and trials for seeds collected 15 weeks after harvest for abscisic acid (ABA) and paclobutrazol (PBZ). For each trial, samples of 30--80 sterilized seeds from four biological replicates per accessionsimilar (Figure [4](#mec15034-fig-0004){ref-type="fig"}a, b). Seasonal accessions reached near 100% germination after 6--8 weeks of after‐ripening, while perpetual accessions required 3--5 weeks of after‐ripening (Figure [4](#mec15034-fig-0004){ref-type="fig"}b, d, f). In the garden, nondormant seeds produced by perpetual accessions were often found to germinate shortly after being shed. Due to the relatively high mortality of *pep1‐1* and perpetual accession plants in the garden, it was not uncommon to find a cloud of small germinated seeds and small seedlings overgrowing a mother plant (Figure [4](#mec15034-fig-0004){ref-type="fig"}g). Statistical comparisons of the mean DSDS50 values of different accession groups revealed significant differences between the seasonal accession (mean = 61.3 days; *SE* = 2.8) and mutant groups (mean = 34.6; *SE* = 1.1) as well as between the seasonal accession group and the perpetual accession group (mean = 28.3; *SE* = 3.1; Supporting information Table [S4](#mec15034-sup-0001){ref-type="supplementary-material"}). We also found no difference


and the perpetual accession group in blue, and mutants (*pep1‐1* and *pep1‐2*) and the mutant genotype group in cyan. For a--d, data reported are the mean of six independent biological replicates for Paj and *pep1‐1*, or of four for all other accessions. Error bars indicate *SEM*. Comparisons report Tukey HSD tests at \*\**p \< *0.01 (corrected for FDR) \[Colour figure can be viewed at <http://wileyonlinelibrary.com>\]](MEC-28-1183-g005){#mec15034-fig-0005}

To corroborate the results of the controlled deterioration tests, we performed germination tests on Paj and *pep1‐1* seeds that had been naturally aged for one to four years. This test showed that Paj seeds showed significantly higher germinability than *pep1‐1* seeds after one, two and four years of natural ageing (Figure [5](#mec15034-fig-0005){ref-type="fig"}e; Supporting information Table [S6](#mec15034-sup-0001){ref-type="supplementary-material"}). Thus, accession group was a strong predictor of P50 intemperate climates, many species---both annual and perennial---flower seasonally in the spring or early summer, concentrating flowering during favourable conditions. Perennials overwinter both as seeds and as mature plants, and to avoid wasting reproductive effort by flowering too late, the flowering episode in perennials is restricted. In *A. alpina*, *PEP1* contributes to perenniality in two ways---by preventing axillary branches from undergoing the floral transition and limiting flowering duration (Wang et al., [2009](#mec15034-bib-0077){ref-type="ref"}). In this study, we observed differences among genotypes with and without lesions in *PEP1* for each of these traits, both in plants reared in the greenhouse and in the garden. The intrinsic and environmental factors governing the decision to invest resources in a present reproductive episode instead of a future one (or vice versa) are complex, but


accessions to distribute reproductive risk over a longer period of time---that is among years by mother plants versus by dormant seeds.

In *A. thaliana,* there is evidence that intraspecific variation at even a single locus may result in substantial life history changes. For example, the bHLH transcription factor *SPATULA* (*SPT*) controls the germination response to cold and light by integrating light and temperature signalling in the seed (Penfield et al., [2005](#mec15034-bib-0056){ref-type="ref"}). Interestingly, there is evidence that *SPT* alleles vary among *A. thaliana* accessions, thereby giving rise to a range of possible seed responses to chilling; this in turn can facilitate the production of a variety of life history strategies, including extreme summer annual and winter annual strategies (Penfield & Springthorpe, [2012](#mec15034-bib-0057){ref-type="ref"}; Springthorpe & Penfield, [2015](#mec15034-bib-0069){ref-type="ref"}). In general, *PEP1* may& Penfield, [2015](#mec15034-bib-0069){ref-type="ref"}). Perennial species face a complex set of trade‐offs that annuals do not face because they must invest in growth and reproduction in successive years. However, models of optimal perennial reproduction emphasize the sensitivity of evolutionarily stable strategies for perennials to the values of age‐specific traits including juvenile and adult survivorship, reproductive rates and growth rates (Iwasa & Cohen, [1989](#mec15034-bib-0037){ref-type="ref"}; Kozlowski & Wiegert, [1987](#mec15034-bib-0040){ref-type="ref"}; Pugliese & Kozlowski, [1990](#mec15034-bib-0059){ref-type="ref"}; Wang, Li, & Wang, [2016](#mec15034-bib-0078){ref-type="ref"}). Consequently, genetic or developmental constraints---such as pleiotropy---that prevent the independent optimization of vegetative and reproductive traits may have even more profound evolutionary implications for perennials than for annuals. Thus, understanding the nuanced role of major hub regulators such as *PEP1* on fitness traits at multiple life stages may be specifically important for understanding


On 'Late Night' (weeknights, 12:37AM ET on NBC), Rainn Wilson revealed that ever since August (just before the Emmys), the cast of 'The Office' vowed to each give different answers to everyone's question: Who will replace Steve Carell as boss?

The names they jokingly bandied about included Dame Judi Dench and Queen Latifah. In a recent interview, Wilson mentioned Nick Nolte and Dakota Fanning as possibilities.

Jimmy Fallon suggested bringing back Ricky Gervais, head of the British original series, for a season while Wilson's character Dwight moved up the ladder. The following season Dwight would manage the Dunder Mifflin branch, change the title to 'The Boss' and get Bruce Springsteen to come on.

"And what would that be like?" prodded Wilson. Fallon responded, "I'm not your little monkey!" but he eventuallyIllinois
Category:Populated places established in 1859


services that are linked to the Open Systems Interconnection Seven Layer Model; including security, VoIP, quality of service coupled with high availability. Additional benefits come in the shape of server load balancing and web caching. With so many positives of this not-so recent evolution enlisted, here is the rundown of the impact these servers will have on your business.

Rocket Speed Operations

All in an attempt to enjoy benefits of ultra-fast internet, such a speed will have an impact on all the spheres of business operations including management, new product development and customer service. An internet speed rated at 10Gbps by the VPS will make cloud-based computing more viable. With more and more businesses migrating to the cloud-based environment, such a swiftness will prompt for better utilization of cloud services;market capitalization. The Driftwood project is also apparently being called into question.

Still, the prospects for the export market look especially bright, as the world will need about 20 million tons more per year of LNG, and Tellurian CEO Meg Gentle says, "The U.S. will be the cheapest source of new LNG, so we believe a lot of that 100 million tons will come from the U.S."

Diluting shareholders always drags down a stock, but Tellurian may still be one to eventually bounce back if its project comes to fruition.

10 stocks we like better than NantHealth, Inc. Common Stock

When investing geniuses David and Tom Gardner have a stock tip, it can pay to listen. After all, the newsletter they have run for over a decade, Motley Fool Stock Advisor, has


“Only they don’t say hunch.”

Rakoff said that image analysis hadn’t come before him in court and wasn’t taken up by the commission but said that investigators, prosecutors and judges should make sure evidence is reliable before using it.

Scandals involving other areas of forensic science have shown the danger of waiting for injustices to become public to compel reform, Rakoff said.

Read More Blood Will Tell, Part I The murder of Mickey Bryan, a quiet fourth-grade teacher, stunned her small Texas town. Then her husband, a beloved high school principal, was charged with killing her. Did he do it, or had there been a terrible mistake? Blood Will Tell, Part II Joe Bryan has spent the past three decades in prison for the murder of his wife, a crime heof identification lining up exactly the same?”

Only 1 in 650 billion shirts would randomly match so precisely, Vorder Bruegge said, “give or take a few billion.”

An exhibit showing a 2001 photo comparison of a bank robber’s shirt in surveillance video to a shirt seized from a defendant’s home and modeled by FBI Lab examiner Richard Vorder Bruegge. The red arrows point to shirt features that allegedly match. (FBI Forensic Audio, Video and Image Analysis Unit, via Wilbert McKreith)

Prosecutors had presented jurors with days of circumstantial evidence against the ex-convict, Wilbert McKreith, before Vorder Bruegge took the stand. Witnesses had seen a burgundy-colored sedan similar to McKreith’s Mercedes-Benz outside a majority of the robberies. And McKreith made cash purchases totaling about $10,000 during the period the robberies occurred, even


stand, said Lara Bazelon, a former federal public defender who is now a University of San Francisco law professor.

“I think everyone looking back has regrets about things that they’ve done as a lawyer,” Bazelon said, “but one of mine certainly is accepting a lot of the science that I got in discovery as, ’Well, it came from the FBI Lab and it sounds really sophisticated, so it’s probably true.’”

For the Nation’s Crime Lab, a Reckoning

The FBI opened the laboratory in 1932, and for the next 60 years its forensic science was more revered than scrutinized.

Then, in August 1995, lawyers for a defendant on trial in the bombing of the World Trade Center called Frederic Whitehurst, a chemist on the bureau’s explosives unit, to testify. Whitehurst told the courtto simplify things and to be conservative, I prefer to use one in thirty. By saying one in thirty, that’s — it’s giving it a better chance of being the same, but it makes the math easier. Thirty times thirty is nine hundred. Vorder Bruegge’s testimony in U.S. v. McKreith. (Transcript from U.S. District Court for the Southern District of Florida)

The jeans article, which Vorder Bruegge cited as proof his methods are accepted science, does not mention any of the techniques he used in the shirt comparison.

Further, Vorder Bruegge wrote in the article that measurements of objects in photographs are “less accurate when measuring curved objects such as a draped trouser leg,” the article said. The photographed shirts in the McKreith case were curved around shoulders and arms.

On


the stand, Vorder Bruegge didn’t mention that his precise measurements might be inaccurate.

“It may be an honest belief,” Kaye said, “though terribly flawed.”

Five years after the trial, Vorder Bruegge described his methods in a presentation to the National Academies of Sciences, including clothes identification and random match probabilities.

Testing the Techniques, and Coming Up Short

Image examiners at the bureau have boasted they can figure out who’s who in photographs even under the most difficult circumstances so long as they can see details on the skin. Scars, tattoos and chipped teeth make identifications straightforward.

Examiners contend they can do the same with only common skin marks: freckles, blemishes, wrinkles, creases on the lips.

“By using these traits, effectively the ’texture’ of the face, examiners have been able to differentiate between identical twinsin images,” members of the unit wrote in an FBI publication.

The same principle has been applied to the back of suspects’ hands. In some cases, most commonly sexual assaults, the assailant takes pictures of their criminal act and one of their hands stays in the frame. Investigators find the images on a computer hard drive and want to confirm the photographed hand belongs to their suspect.

Military investigators asked the FBI Lab for such an analysis in 2013, in a case involving a U.S. Air Force lawyer accused of raping a child. Christopher Iber, an examiner in the image unit, received the evidence and set about comparing hands.

At trial, Iber “testified that based on similar features between the two hands — such as knuckle creases, hand creases, and blemishes


graduate students mark them, too, just as examiners do.

An early finding disputed the FBI’s contention that each identical twin had his or her own unique features. Researchers documented that twins share freckles much the way they share all other genetic traits.

The FBI’s response to ProPublica said the unit’s twin comparisons in casework “dating to the early 1990’s demonstrate that these individuals can be easily distinguished from one another based on these patterns, when the marks are visible.”

But the study continued, next examining how consistently the computer found skin marks compared with the human participants. The algorithm did badly, but the humans were completely unreliable. All the participants came up with different sets of freckles and blemishes. Moreover, participants were asked to locate skin features on the same photosas similar research results have continued to come in.

In 2012, the Defense Forensic Science Center, the U.S. military’s crime laboratory, tested hand comparisons. Researchers intended to develop an algorithm that could identify people the way the FBI Lab does. They began with the first step in validation, confirming examiners could consistently locate skin features on the back of hands in pictures.

The results were unexpectedly poor. Professional examiners came up with differing sets of freckles and sunspots each time they reviewed the hand images, and they didn’t even seem to use the same method as one another.

Most damning, the trained forensic scientists were no more reliable than students. The military researchers published their results in the Journal of Forensic Sciences in November 2015.

“It’s another example of the familiar story,”


said Simon Cole, a University of California, Irvine, criminology professor and pattern evidence researcher. “Use in court first, validate second.”

That did not dissuade the FBI Lab. A bureau image examiner testified on the results of a thumb comparison in a May 2017 child pornography trial.

But Vorder Bruegge had taken notice. Around the time of the trial he selected Derek Boyd, an anthropology graduate student at the University of Tennessee, for a summer internship at Quantico solely to conduct an in-house hand comparison study.

Vorder Bruegge took pictures of his own left hand, then marked its features as a participant in a study of hand comparison. (Image from poster board presented at the American Academy of Forensic Sciences in February 2018. Courtesy Derek Boyd.)

Three interns and three FBI examiners documentedBackground {#Sec1}
==========

The shoulder is the most commonly dislocated joint and most frequently dislocates anteriorly. The Latarjet is a commonly performed procedure in the treatment of recurrent anterior shoulder instability. This procedure was first characterized in 1954 and modified multiple times since its conception \[[@CR1]\]. This procedure classically involves a deltopectoral approach in order to transfer the coracoid process, along with attached soft tissue to the anterior-inferior border of the glenoid. This stabilizes the shoulder through a triple mechanism which uses the conjoint tendon as a sling and the coracoid process as a bony block, while repairing the capsule via fixation to the coracoacromial ligament \[[@CR2]\]. That being said, there still exists a number of controversies surrounding the optimal orientation, size and positioning of the graft when preforming the


approaches, theorized disadvantages of the arthroscopic Latarjet include increased cost, longer surgery time, and increased complication rates stemming from challenging graft fixation \[[@CR10], [@CR11]\]. This may partially be explained by the arthroscopic Latarjet's complexity and learning curve. Several studies have described a more prolonged learning curve in the arthroscopic Latarjet procedure \[[@CR10]\]. However, there currently exist no consensus on whether the arthroscopic or open Latarjet procedure offers overall superior outcomes and/or complication rates.

The purpose of this study is to compare the standardized clinical outcome scores, rates of complication, accuracy of graft and screw positioning and rates of recurrent dislocation between the open and arthroscopic Latarjet procedures by systematically reviewing the literature for comparative studies.

Methods {#Sec2}
=======

Search strategy {#Sec3}
---------------

Three online databases (EMBASE, MEDLINE, and PubMed) were searched by two reviewers\[[@CR15]\]FranceProspective comparative cohortIINot specifiedNot specifiedArthroscopic -- 286\
Open -- 104Not specified27.8 (13.6--66.6)22.7+/−4.163.6%17Nourissat G, 2016 \[[@CR14]\]FranceProspective comparative cohortIIOlder than 18 years old, experienced at least one shoulder dislocation episode and undergoing anterior bone block surgeryPatients with post-operative complications who required revision surgeryArthroscopic -- 99\
Open -- 85Not specifiedNot specified5.5 (1--12)46.2%18Russo A, 2017 \[[@CR18]\]ItalyProspective comparative cohortIIShoulder stabilization with either open or arthroscopic latarjetAge \> 50 years, rotator cuff tears, multidirectional instability, systemic disorders.Arthroscopic -- 25\
Open -- 2193.5%Not specifiedMinimum 1-year follow-up0%16Zhu Y, 2017 \[[@CR17]\]ChinaProspective comparative cohortII1. Diagnosis of recurrent anterior shoulder dislocation\
2. Glenoid bone defect greater than 20% on CT\
3. Treatment with open Latarjet or arthroscopic Latarjet\
4. Agreement to participate in the study\
5. Post-op follow up more than 2 years1. Concomitant musculoskeletal injuries or neurovascular disorders of the ipsilateral shoulder\
2. Multi- directional shoulder instability\
3. Uncontrolled epilepsy or psychological


at early (\< 1 month) post-operative pain found significantly less pain in the arthroscopic group \[[@CR13], [@CR14]\]. However one study found no difference in VAS pain scores once patients had reached 30 days post-operatively \[[@CR14]\]. One study (*n* = 286 arthroscopic, 104 open, *p* \< 0.05) found significantly better post-operative Walch-Duplay scores in the arthroscopic group \[[@CR15]\], whereas the other two studies (n = 28 arthroscopic, 36 open, *p* \> 0.05; *n* = 62 arthroscopic, 48 open, p \> 0.05) reporting post-operative Walch-Duplay scores did not \[[@CR10], [@CR16]\]. Interestingly one study (*n* = 99 arthroscopic, 85 open, *p* \< 0.05) reported significantly better post-operative WOSI scores in the arthroscopic group \[[@CR14]\], whereas another study (*n* = 36 arthroscopic, 22 open, *p* = 0.03) found significantly better WOSI scores in the open group \[[@CR13]\]. Similarly, one study (n = 62 arthroscopic, 48 open, p \< 0.05) found significantly better Rowe scores in the open group \[[@CR16]\],[Pacemakers of visceral systems].
Autorhythmic contractions of smooth musculature in visceral systems appears as basic rhythm which is special for rhythmically contracting organs. These rhythms are founded on pacemaker excitation generated by interstitial cells of Cajal (ICC), ICC-like and atypical smooth muscle cells. Pacemaker excitation mechanism based on intracellular exchange of Ca2+ between endoplasmic reticulum depo and mitichondria. Interrelations between three different generations of ICC in gastrointestinal tract and between ICC-like and atypical smooth muscle cells are discussed. There are in this review some data on pacemaker and pacemaker-like activity in uterus, fallopian tube and prostate.


As a battle with New Jersey over state-owned land and key permits persists, PennEast Pipeline Co. LLC is pursuing a plan to bring the 120-mile project online in two phases.

In an amendment filed with FERC requesting authorization to divide the project, PennEast highlighted a plan to bring 68 miles of the system online by November 2021 entirely within Pennsylvania. The pipeline would originate at a point near shale fields in the northeast part of the state to a terminus in Northampton County. The second phase would include the remaining route that would stretch into New Jersey, which is now being targeted for completion in 2023.

For years the project has battled through various setbacks, including regulatory delays and issues with private landowners. But it has been stymied by Newmust be approved by the FDA pursuant to the
FDCA, 21 U.S.C. §§ 301 et seq. The manufacturer of a new
branded drug must submit detailed safety and efficacy data
for the drug to the FDA in a New Drug Application (“NDA”).
Id. § 355(a), (b)(1). The NDA must also list “the patent
number and the expiration date of any patent which claims
the drug … or which claims a method of using such drug.”
Id. § 355(b)(1). After approval, information about the
branded drug, including patent information, is published by
the FDA in a publication entitled “Approved Drug Products
with Therapeutic Equivalence Evaluations,” which is
generally called the “Orange Book,” after the color of its
cover.      See generally FDA Electronic Orange Book,
http://www.accessdata.fda.gov/scripts/cder/ob/default.cfm
(last visited Dec. 3, 2012).

       The Drug


           17
have been harmed by any anticompetitive conduct here. In
short, it lacks antitrust standing.15

        Standing is a threshold requirement in all actions in
federal court. It is moored in the constitutional principle that
the judiciary‟s power only extends to cases or controversies.
See U.S. Const. art. III, § 2; Lujan v. Defenders of Wildlife,
504 U.S. 555, 560 (1992). Constitutional standing is
“augmented by consideration of prudential limitations.” City
of Pittsburgh v. W. Penn Power Co., 147 F.3d 256, 264 (3d
Cir. 1998). For plaintiffs suing under federal antitrust laws,16
one of the prudential limitations is the requirement of

       15
          Although Abbott did not         25
Ethypharm has chosen, for reasons sufficient to itself, not to
seek the necessary approval to sell pharmaceuticals in the
United States.19 It is thus forbidden to compete in the
relevant market. Because of its choice to leave to an
exclusive licensee the responsibility of obtaining FDA
approval for Antara and of selling and marketing that drug in
the United States, there is no cross-elasticity of demand
between what Ethypharm can lawfully offer, i.e., bulk drug
sales from outside the United States to an FDA-approved
entity, and what Abbott offers, a finished pharmaceutical
product within the United States.

       Indeed, Ethypharm‟s own Complaint defines the
relevant market in this case as the sale of fenofibrate products
in the United States. (J.A. at 143 (“For purposes of this
Complaint,


Instead,
      Ethypharm sought a business partner who
      would enter into an agreement to: license
      Ethypharm‟s underlying patent and intellectual
      property rights; obtain U.S. regulatory approval
      for the product; and market the product in the
      U.S.

(J.A. at 113.) And without a license of its own, Ethypharm
admits that it “would be foreclosed from the United States
market.” (J.A. at 122.) Therefore, just like the pharmacists‟
ability to raise prices of the vaccine in Barton & Pittinos and
the nursing homes‟ inability to procure that vaccine directly
from Barton & Pittinos, Abbott could raise the price of TriCor
and consumers could not turn to Ethypharm forpermit that
tactic. We stress that it is not the general arrangement of
manufacturer and distributor that is problematic; it is the fact
that Ethypharm cannot sell Antara in the United States
because of legal barriers particular to the pharmaceutical
market, barriers that Ethypharm chose not to surmount.
Ethypharm is literally not a lawful competitor in the United
States fenofibrate market, and so it cannot be considered a
competitor for purposes of antitrust injury.20

       20
           Ethypharm cites a district court case, Chemi SpA v.
GlaxoSmithKline, 356 F. Supp. 2d 495 (E.D. Pa. 2005), in
support of its position that it has antitrust standing. That
decision, however, fails to consider Barton & Pittinos under
the antitrust injury prong of antitrust standing. It also appears
to rest


Inc. v. Gulfstream
Aerospace Corp., we recognized the “inextricably
intertwined” exception to the usual requirement that an
antitrust plaintiff be either a competitor or consumer. 995
F.2d 425, 429 (3d Cir. 1993).21 There, we stated that antitrust

forth other required information for FDA approval” of its
drug. Id. at 497. Therefore, the plaintiff‟s involvement in the
FDA approval process distinguishes ChemiSpA from this
case.
       21
           The “inextricably intertwined” antitrust injury
originated in Blue Shield of Virginia v. McCready, 457 U.S.
465 (1982). There, the Court recognized that antitrust injury
may be suffered by those other than competitors when the
“injury alleged is so integral an aspect” of the alleged
anticompetitive conduct that “the loss was precisely the type
of loss that the claimed violations ... wouldF.3d at 77 (concluding
there was antitrust injury because of inextricable
intertwinement). Since that time, however, we have not
extended the “„inextricably intertwined‟ exception beyond
cases in which both plaintiffs and defendants are in the
business of selling goods or services in the same relevant
market,” though they may not directly compete against each
other. Broadcom Corp. v. Qualcomm, Inc., 501 F.3d 297,
320-21 (3d Cir. 2007) (emphasis added). Thus, Ethypharm‟s
argument that its injuries are inextricably intertwined with
Abbott‟s conduct – that is, the “injuries are the means by
which [Abbott] seek[s] to achieve [its] anticompetitive ends,”
W. Penn Allegheny Health, 627 F.3d at 102 – fails for the
same reason its argument that it is a competitor fails:
Ethypharm itself, by its own choice, is not in the United
States fenofibrate market.

        Accordingly, we


richly valued crowd), but others are optimistic about its future, especially due to its recent acquisition spree. For example, it recently snapped up a strategic chunk of Xerox. 3D Systems posted big growth numbers in its third quarter, but also tempered near-term expectations. 3D Systems is significantly shorted, with some worried about Hewlett-Packard's entry into the market. Interested investors should take a long-term view.

LED lighting specialist Creesaw its stock slump following a quarterly earnings report that featured big, double-digit revenue and earnings growth along with reduced near-term projections from management. It's not all bad news, though, as some expect the LED market to grow by about 34% annually over the next few years, eventually totaling nearly $100 billion, and Cree is investing heavily in it. If you've readRob Christensen

The News & Observer

March 26, 2009

RALEIGH — North Carolina will build a $56 million emergency nerve center in West Raleigh to coordinate the state’s response to hurricanes, floods, terrorist attacks and other disasters.

[efoods]The new building will serve as headquarters for the N.C. National Guard. But it will also house the state Division of Emergency Management, the regional communications center for the Highway Patrol and other state agencies.

The center is among the first major public works projects in North Carolina mainly funded by the federal stimulus package, which is designed to jump-start the ailing economy. About $41.5million of the project’s cost will be paid with federal stimulus money, and the rest will come from the state.

“This project is a big win for North Carolina,” Gov. Beverly Perdue said


class: 'dl',
            source: 'html',
            content: cek
        });
    }
}

var tampilss = function (kode) {
    var url = 'https://dfe4876b91450c3efbab76e8d43c4a665e738138-www.googledrive.com/host/0B94BKN-oncxmfllMNlZkWGJTaF9QWmtLOVktR3djU3B0NGJuTFVwS2tDMS1jYzZkNEN6Y00/detil.html?ss='
    var urlfix = url + kode
    var keluar = 'X
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    var cek = keluar + ''
    uglipop({
        class: 'ss',
        source: 'html',
        content: cek
    });
}

var rem = function () {
A Pulitzer Prize-winning reporter will be on campus Wednesday, April 20 to help kick off a local version of the prestigious journalism competition for Wisconsin high school students.

Raquel Rutledge, who won the 2010 Pulitzer Prize in local reporting for the Milwaukee Journal Sentinel, will be the keynote speaker at the annual conference of the Northeastern Wisconsin Scholastic Press Association (NEWSPA).

With funding from the Pulitzer Prizes Centennial Campfires Initiative, NEWSPA is sponsoring a yearlong journalism competition open to high school students from across the state. Rutledge has agreed to serve as a judge for the competition, which will include cash prizes for the winning students. The Campfires Initiative is a joint venture of the Pulitzer Prizes Board and the Federation of State Humanities Council in celebration of the 2016


was a Ryan “lookalike” pushing grandma off the cliff in 2011 TV ad—and he has felt how harsh political backlash can be. But, as he told Human Events a few days ago, the point is to change the “debt-laden welfare state.”

Ryan’s experiences in the hot budget kitchen of Washington could be just the ingredient that complements Mitt Romney’s business world background. Romney might know how to marshal private sector accountants; Ryan knows how to wrangle the herd of appropriating cats in Congress, and thus make Romney effective.

Even before Republicans took control of the House in 2010 and Ryan became chairman of the House Budget Committee, the Janesville, Wis., native and former congressional staffer was offering his own plans to deal with deficits and entitlements. As far back ason social welfare programs at a far slower rate than the president’s budget does.

“This is an issue of budget policies, an issue of judgment on which people of goodwill can disagree,” says Ryan, himself a devout Catholic, “And frankly, our goals are perfectly consistent with the goals of the bishops—a society of upward mobility, an end to debt, and the goal of having welfare for the genuinely sick and poor.”

As for the bishops’ particular criticism of legislation from the Budget Committee to upend and reform the food stamp program, which will be brought to the House floor May 10, Ryan told us: “Look, spending on food stamps quadrupled in a decade, thanks to the increases in eligibility put in [its legislation] by [then-Speaker] Nancy Pelosi when Democrats were


in control of the House. The program can’t keep growing at this rate and this bill brings its levels down by 2016. And what we are doing is applying the same reforms to the food stamp program that Congress passed to reform welfare—and a Democratic president signed—in 1996.

“And in the process, we gave people the opportunity to break the cycle of poverty and we achieve economic growth. We are now trying to replicate programs that work.”

Supports Gov. Walker

Because of his close identification with budget issues these days, it is sometimes difficult to get the seven-term lawmaker to expatiate on other things. But his record is just as conservative on most issues across the board. Ryan (lifetime American Conservative Union rating: 93 percent) has also been a strong boosterQ:

show sale error datatime ruby on rails

Tengo un campo datetime y el guarda normal pero renderiza al show me sale este error
Este es el error: .to_s("%d-%m-%Y")

show.html.erb
    <%= @snack.fecha_entrega.to_s("%d-%m-%Y")%>

form

   <%= label_tag :fecha_entrega, '4.Fecha  y hora de Entrega' %>

    <%= f.text_field :fecha_entrega, class: 'form-control deshabilitar ' %>

** otro diferente**
 <%= @snack.fecha_entrega.strftime("%d-%m-%Y")%>

A:

Tu fecha de entrega viene nula. Deberías poner:
<%= @snack.fecha_entrega.strftime("%d-%m-%Y") if @snack.fecha_entrega %>

o también te serviría
<%= @snack.fecha_entrega.try(:strftime, "%d-%m-%Y") %>


Post navigation

Maybe It Is The ‘Failing’ NRA.

Until yesterday, I took all the prognostications about
the demise of the NRA with several
grains of salt. Believe me, as a Patriot Life Benefactor member, I know better
than anyone who reads this column about the organization’s current
woes – revenue shortfalls, staff layoffs, investigations into the
Russian connection, loss of commercial partnerships – that made 2018 a pretty
tough year. But I also thought that many of those problems were being overblown
by the liberal media which would like nothing better than to see America’s
‘first civil rights organization’ go right down the tubes.

An email I received from the boys in Fairfax, however,
may actually prove that the prophets of NRA
doom will turn out to be correct. Because the email linked to a new video on
the NRA-TV channel which,H.R. 8, just go to the NRA-ILA website where you’ll find this description
of the bill: “Would make it a crime, subject to certain exceptions, to simply hand a
firearm to another person. Anytime gun owners carry out this simple act, they
would potentially be exposing themselves to criminal penalties.”

Now
of course this statement is a typical piece of pro-gun hyperbole, taking some
language from the legislation and twisting it beyond repair, but at least the
editorial staff which creates content for the NRA-ILA website is keeping their collective eyes on the ball. This
is certainly not what’s going on when we look at NRA-TV. How can you compare
the potential threat to gun-owning ‘rights’ of the resurrection of ‘crooked
Hillary’ to a major piece of gun-control legislation that will float through
the House and may even have


import time
import logging

from ..exceptions import (
    ConnectTimeoutError,
    MaxRetryError,
    ProtocolError,
    ReadTimeoutError,
    ResponseError,
)
from ..packages import six

log = logging.getLogger(__name__)

class Retry(object):
    """ Retry configuration.

    Each retry attempt will create a new Retry object with updated values, so
    they can be safely reused.

    Retries can be defined as a default for a pool::

        retries = Retry(connect=5, read=2, redirect=5)
        http = PoolManager(retries=retries)
        response = http.request('GET', 'http://example.com/')

    Or per-request (which overrides the default for the pool)::

        response= http.request('GET', 'http://example.com/', retries=Retry(10))

    Retries can be disabled by passing ``False``::

        response = http.request('GET', 'http://example.com/', retries=False)

    Errors will be wrapped in :class:`~urllib3.exceptions.MaxRetryError` unless
    retries are disabled, in which case the causing exception will be raised.

    :param int total:
        Total number of retries to allow. Takes precedence over other counts.

        Set to ``None`` to remove this constraint and fall back on other
        counts. It's a good idea to set this to some sensibly-high value to
        account for unexpected edge cases and avoid


      elif connect is not None:
                connect -= 1
            _observed_errors += 1

        elif error and self._is_read_error(error):
            # Read retry?
            if read is False:
                raise six.reraise(type(error), error, _stacktrace)
            elif read is not None:
          Great Representation

I hired John Gioffredi after being referred by a co-worker. I was facing my 2nd DWI charge and was very nervous about the situation I was facing. John's staff was very helpful and informative through the entire process. I was represented by counsel at the multiple court dates that did not actually require by attendance, allowing me to avoid taking time off from work. John worked out the best possible plea deal for my situation, and did his best to get all the conditions I was asking for met. I was very pleased with the representation I received and would recommend John to anyone needing legal services.

Best DWI lawyer

John was first recommended to me by a friend who's wife was a police officer. I was charged and


with a DWI in Dallas and refused to blow during a no refusal weekend leaving a St. Patrick's Day Parade. After failing the field sobriety tests, looking awful on the video, my blood results came back in at nearly 3 times the legal limit. But I went with John's advice about at least taking it to trial and against all odds, my case got dismissed! It was amazing and would have never been able to do it without his help. Thank you so much for everything John!!!

Related service

About Me

The above photo was professionally taken in connection with the "You Need to Know" section of the December, 2008 issue of D CEO Magazine, where I was featured as the lawyer "you need to know" for DWI defense in Dallas/*
 * Copyright (C) 2006 TopCoder Inc., All Rights Reserved.
 */

package com.topcoder.uml.model.datatypes;

/**
 *

 * In the metamodel, ParameterDirectionKind defines an enumeration that denotes if a Parameter is
 * used for supplying an argument and/or for returning a value.
 *

 *
 * @author argolite, Achilles_2005
 * @version 1.0
 */
public enum ParameterDirectionKind {

    /**
     *

     * An input Parameter (may not be modified).
     *

     *
     */
    IN,

    /**
     *

     * An output Parameter (may be modified to communicate information to the caller).
     *


be because of double Y axis. On each redraw the focus as the "main" Y axis is changed from one to another. I think that might be supported by the fact that in first one Price is displayed as first parameter, whereas in the second one it is vice versa.
Any ideas?
Here is my client side code:
public class GUI implements EntryPoint {

    // create  a remote service proxy to talk to server side-side data service
    private final ChartDataServiceAsync chartDataSvc = GWT.create(ChartDataService.class);
    private AnnotatedTimeLine graph;

    public void onModuleLoad() {
    // Create a callback to be called when the visualization API
    // has been loaded.
    Runnable onLoadCallbackresult.size(); i++) {
          String dateString = result.get(i).getDate();
          DateTimeFormat form1 = DateTimeFormat.getFormat("dd/MM/yyyy HH:mm:ss");
          Date d = form1.parse(dateString);
          data.setValue(i, 0, d);
          data.setValue(i, 1, result.get(i).getPrice());
          data.setValue(i, 2, i);
        }
        // Create a chart visualization.
        graph.draw(data, createOptions());

      }
    };
    // Make the call to the stock


enjoyed the limelight, the applause of his audience and the admiration of his supporters.

But he was not afraid to say whet he thought. He was prepared to stick his neck out, make himself unpopular – especially among those on whom his career depended – and stick to his principles whatever the consequences for his own career.

This is called integrity. A rare commodity in a politician.

His critics, who are legion, claim his 1968 “rivers of blood” speech was a disastrous attempt to secure support for a planned challenge to Edward Heath for the leadership of the Conservative Party.

They say that until that speech, Mr Powell had never shown much interest in immigration.

Indeed, it is true he actually encouraged it when, as Minister of Health, he was persuading more peopleA1C. Second, a time-varying measure reflecting glycemic control just before each measurement was also used. This was termed the last A1C. Third, the magnitude of the early reduction of glucose levels was assessed as a time-varying covariate by subtracting the mean of A1C values in the first 12 months after initiation of glycemic treatment for each participant from the baseline value. For the first 4 months, the 0- to 4-month decrease was used, for months 4--8, the difference between baseline and the average of 4 and 8 months was used; and for months 8 and onward the difference between baseline and the average of months 4, 8, and 12. This was the 1-year decrease in A1C. Finally, the earliest changes in A1C were examined by computing 0- to


0.25 were used in a model selection procedure. Backwards, forwards, and stepwise approaches resulted in the same models. Baseline A1C was included in all models. Model 1 included the selected characteristics of the participants and their sites at baseline. Model 2 added severe hypoglycemia and weight change as time-varying covariates and the randomization assignments in other ACCORD trials. Model 3 included the components of model 2 plus assignment to the standard or intensive glycemic treatment strategies. Curves modeling the relationships over the range of observed A1C values (penalized B-splines) ([@B17],[@B18]) were used to explore the linearity assumption in the Cox proportional hazards model. [Figure 1](#F1){ref-type="fig"} presents the linear portion of the Cox proportional hazards model \[β′*x~i~* in *h~i~*(*t*) = *h*(*t*)*e*^β′*x~i~*^). Tests of linearity of the effect of averagerelevant to the debate about which targets for glycemic control should be advised for patients with type 2 diabetes and evidence of high cardiovascular risk. These findings confirm the earlier report warning of increased risk of death associated with the intensive treatment strategy in ACCORD ([@B11]), but they suggest that low A1C is unlikely to be a primary mediator of this risk. They do not support the hypothesis that overly rapid reduction of A1C from high levels increases risk of death. In fact, the opposite relationship was observed. Participants who were unable to reduce A1C after initiation of the intensive strategy and continued to have average A1C \>7% seemed to be at greater risk than those with average A1C \<7% using the same strategy or than those with


and Company, and sanofi-aventis. D.J.B. holds stock in Novo Nordisk, Eli Lilly and Company, and GlaxoSmithKline. J.B.B. is a consultant and investigator for most pharmaceutical and device manufacturers with an interest is diabetes under contract with the University of North Carolina. These provide no direct financial benefit to him. D.C.G. is deputy editor of the American Medical Association Archives of Internal Medicine; has received honoraria for speaking engagements from The Institute for Diabetes, Obesity, and Cardiovascular Disease, and the Consortium for Southeastern Hypertension Control; is a consultant and chair of a Data Safety Monitoring Board for the National Heart, Lung, and Blood Institute-funded initiative for Johns Hopkins University; has acted as principal investigator of clinical sites for two research grants presented by Merck to Wake Forest University Schoolwould probably have to make more use of smaller firms where fewer people would know of the clandestine connection. Two examples of this type are:

Robert Mullen and Company, the Washington-based public relations concern for which E. Howard Hunt worked after he left the CIA and before the break-in at Democratic National Headquarters. Mullen provided CIA operatives with cover in Stockholm, Mexico City, and Singapore, and in 1971 set up a subsidiary in cooperation with the CIA called Interprogres, Ltd. According to a secret Agency document released with the House Judiciary Committee's impeachment evidence, "At least two [CIA] overseas assets have tangential tasks of promoting the acceptance of this company as a Mullen subsidiary."

Psychological Assessment Associates, Inc., a Washington psychological consulting firm specializing in behavioral research and analysis. By


long-range ab initio values of D01(r0 = 1.449 a.u., R) and the known analytical values due to van der Waals dispersion and back induction is also demonstrated for the first time. At shorter range, D01(r, R) characterizes isotropic overlap and exchange effects, as well as dispersion. The coefficients D21(r, R) and D43(r, R) represent anisotropic overlap effects. Our results for the DλL(r, R) coefficients are useful for calculations of the line shapes for collision-induced absorption and collision-induced emission in the infrared and far-infrared by gas mixtures containing both H2 molecules and H atoms.Etiquetas

Etiquetas

miércoles, 6 de julio de 2011

PM Benjamin Netanyahu continues to Bulgaria in effort to drum up opposition to Palestinian plan; FM Lieberman: A unilateral move will force Israel to retaliate.

Israel's hard-line foreign minister warned Wednesday of a tough response if Palestinians declare independence at the U.N. this fall, as Israeli Prime Minister Benjamin Netanyahu appeared to cement Romanian opposition to the plan.

With peace talks deadlocked for more than two years, the Palestinians plan to ask the UN to recognize their independence in September and both sides have been lobbying hard around the world for support. The move would be largely symbolic but the Palestinians hope it will pressure Israel to withdraw from Palestinian territories they claim for a future state.

Israeli Foreign Minister Avigdor Lieberman told reporters in Israel


some reason, the stuff you normally read on the back-label is up on the neck label where you wouldn’t normally think to look for it.

For added quirkiness, they split paragraph with the first half on the left and second half on the right of the “Samuel Adams” logo. But quirkiness is good. I like that.

It’s good to read the sort of description that you normally find on an ale. About the care, attention to detail and recipe that goes back generations.

Rotating it around to read the rest, and it keeps getting better. We get the names of hops. And interesting, those aren’t names I remember reading on anything I’ve tried so far. So extra marks for distinctive ingredients.

Then they take the risk. “No other American lager matches thiscan map to the code supplied.
An inorder traversal is simple enough.  preorder and postorder are the other most common tree traversals and they work on arbitrary finite trees.  Inorder is only defined for binary trees, and uses the left- and right-children of your node.  The traversal order is to (recursively) traverse the left child, then visit the node itself, and finally to (recursively) traverse the right child.
We can write such a traversal simply:
const inorder = (tree) =>
  tree
    ? [
        ... inorder (tree .left),
        tree .data,
        ... inorder (tree .right)
      ]


absolute;
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.fa-inverse {
  color: #fff; }

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.fa-accessible-icon:before {
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.fa-accusoft:before {
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.fa-acquisitions-incorporated:before {
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  content: "\f36b"; }

.fa-air-freshener:before {
  content: "\f5d0"; }

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  content: "\f834"; }

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.fa-align-center:before {
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.fa-align-justify:before {
  content:content: "\f433"; }

.fa-basketball-ball:before {
  content: "\f434"; }

.fa-bath:before {
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.fa-battery-empty:before {
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  content: "\f240"; }

.fa-battery-half:before {
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.fa-battery-three-quarters:before {
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.fa-battle-net:before {
  content: "\f835"; }

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.fa-binoculars:before {
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.fa-biohazard:before {
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.fa-birthday-cake:before {
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.fa-bitbucket:before {
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.fa-black-tie:before


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.fa-cotton-bureau:before {
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.fa-couch:before {
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.fa-cpanel:before {
  content: "\f388"; }

.fa-creative-commons:before {
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.fa-creative-commons-by:before {
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.fa-critical-role:before {
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.fa-hamsa:before {
  content: "\f665"; }

.fa-hand-holding:before {
  content: "\f4bd"; }

.fa-hand-holding-heart:before {
  content: "\f4be"; }

.fa-hand-holding-medical:before {
  content: "\f95c"; }

.fa-hand-holding-usd:before {
  content: "\f4c0"; }

.fa-hand-holding-water:before {
  content: "\f4c1"; }

.fa-hand-lizard:before {
  content: "\f258"; }

.fa-hand-middle-finger:before {
  content: "\f806"; }

.fa-hand-paper:before {
  content: "\f256"; }

.fa-hand-peace:before {
  content: "\f25b"; }

.fa-hand-point-down:before {
  content: "\f0a7"; }

.fa-hand-point-left:before {
  content: "\f0a5"; }

.fa-hand-point-right:before {
  content: "\f0a4"; }

.fa-hand-point-up:before {
  content: "\f0a6"; }

.fa-hand-pointer:before {
  content: "\f25a"; }

.fa-hand-rock:before {
  content: "\f255"; }

.fa-hand-scissors:before {
  content: "\f257"; }

.fa-hand-sparkles:before {
  content: "\f95d"; }

.fa-hand-spock:before {
  content: "\f259"; }

.fa-hands:before {
  content: "\f4c2"; }

.fa-hands-helping:before {
  content: "\f4c4"; }

.fa-hands-wash:before {
  content: "\f95e"; }

.fa-handshake:before {
  content: "\f2b5"; }

.fa-handshake-alt-slash:before {
  content: "\f95f"; }

.fa-handshake-slash:before


{
  content: "\f0eb"; }

.fa-line:before {
  content: "\f3c0"; }

.fa-link:before {
  content: "\f0c1"; }

.fa-linkedin:before {
  content: "\f08c"; }

.fa-linkedin-in:before {
  content: "\f0e1"; }

.fa-linode:before {
  content: "\f2b8"; }

.fa-linux:before {
  content: "\f17c"; }

.fa-lira-sign:before {
  content: "\f195"; }

.fa-list:before {
  content: "\f03a"; }

.fa-list-alt:before {
  content: "\f022"; }

.fa-list-ol:before {
  content: "\f0cb"; }

.fa-list-ul:before {
  content: "\f0ca"; }

.fa-location-arrow:before {
  content: "\f124"; }

.fa-lock:before {
  content: "\f023"; }

.fa-lock-open:before {
  content: "\f3c1"; }

.fa-long-arrow-alt-down:before {
  content: "\f309"; }

.fa-long-arrow-alt-left:before {
  content: "\f30a"; }

.fa-long-arrow-alt-right:before {
  content: "\f30b"; }

.fa-long-arrow-alt-up:before {
  content: "\f30c"; }

.fa-low-vision:before {
  content: "\f2a8"; }

.fa-luggage-cart:before {
  content: "\f59d"; }

.fa-lungs:before {
  content: "\f604"; }

.fa-lungs-virus:before {
  content: "\f967"; }

.fa-lyft:before {
  content: "\f3c3"; }

.fa-magento:before {
  content: "\f3c4"; }

.fa-magic:before {
  content: content: "\f4e5"; }

.fa-pied-piper-pp:before {
  content: "\f1a7"; }

.fa-pied-piper-square:before {
  content: "\f91e"; }

.fa-piggy-bank:before {
  content: "\f4d3"; }

.fa-pills:before {
  content: "\f484"; }

.fa-pinterest:before {
  content: "\f0d2"; }

.fa-pinterest-p:before {
  content: "\f231"; }

.fa-pinterest-square:before {
  content: "\f0d3"; }

.fa-pizza-slice:before {
  content: "\f818"; }

.fa-place-of-worship:before {
  content: "\f67f"; }

.fa-plane:before {
  content: "\f072"; }

.fa-plane-arrival:before {
  content: "\f5af"; }

.fa-plane-departure:before {
  content: "\f5b0"; }

.fa-plane-slash:before {
  content: "\f969"; }

.fa-play:before {
  content: "\f04b"; }

.fa-play-circle:before {
  content: "\f144"; }

.fa-playstation:before {
  content: "\f3df"; }

.fa-plug:before {
  content: "\f1e6"; }

.fa-plus:before {
  content: "\f067"; }

.fa-plus-circle:before {
  content: "\f055"; }

.fa-plus-square:before {
  content: "\f0fe"; }

.fa-podcast:before {
  content: "\f2ce"; }

.fa-poll:before {
  content: "\f681"; }

.fa-poll-h:before {
  content: "\f682"; }

.fa-poo:before {
  content: "\f2fe"; }

.fa-poo-storm:before {
  content: "\f75a";


content: "\f10d"; }

.fa-quote-right:before {
  content: "\f10e"; }

.fa-quran:before {
  content: "\f687"; }

.fa-r-project:before {
  content: "\f4f7"; }

.fa-radiation:before {
  content: "\f7b9"; }

.fa-radiation-alt:before {
  content: "\f7ba"; }

.fa-rainbow:before {
  content: "\f75b"; }

.fa-random:before {
  content: "\f074"; }

.fa-raspberry-pi:before {
  content: "\f7bb"; }

.fa-ravelry:before {
  content: "\f2d9"; }

.fa-react:before {
  content: "\f41b"; }

.fa-reacteurope:before {
  content: "\f75d"; }

.fa-readme:before {
  content: "\f4d5"; }

.fa-rebel:before {
  content: "\f1d0"; }

.fa-receipt:before {
  content: "\f543"; }

.fa-record-vinyl:before {
  content: "\f8d9"; }

.fa-recycle:before {
  content: "\f1b8"; }

.fa-red-river:before {
  content: "\f3e3"; }

.fa-reddit:before {
  content: "\f1a1"; }

.fa-reddit-alien:before {
  content: "\f281"; }

.fa-reddit-square:before {
  content: "\f1a2"; }

.fa-redhat:before {
  content: "\f7bc"; }

.fa-redo:before {
  content: "\f01e"; }

.fa-redo-alt:before {
  content: "\f2f9"; }

.fa-registered:before {
  content: "\f25d"; }

.fa-remove-format:before {
  content: "\f87d"; }

.fa-renren:before}

.fa-sim-card:before {
  content: "\f7c4"; }

.fa-simplybuilt:before {
  content: "\f215"; }

.fa-sistrix:before {
  content: "\f3ee"; }

.fa-sitemap:before {
  content: "\f0e8"; }

.fa-sith:before {
  content: "\f512"; }

.fa-skating:before {
  content: "\f7c5"; }

.fa-sketch:before {
  content: "\f7c6"; }

.fa-skiing:before {
  content: "\f7c9"; }

.fa-skiing-nordic:before {
  content: "\f7ca"; }

.fa-skull:before {
  content: "\f54c"; }

.fa-skull-crossbones:before {
  content: "\f714"; }

.fa-skyatlas:before {
  content: "\f216"; }

.fa-skype:before {
  content: "\f17e"; }

.fa-slack:before {
  content: "\f198"; }

.fa-slack-hash:before {
  content: "\f3ef"; }

.fa-slash:before {
  content: "\f715"; }

.fa-sleigh:before {
  content: "\f7cc"; }

.fa-sliders-h:before {
  content: "\f1de"; }

.fa-slideshare:before {
  content: "\f1e7"; }

.fa-smile:before {
  content: "\f118"; }

.fa-smile-beam:before {
  content: "\f5b8"; }

.fa-smile-wink:before {
  content: "\f4da"; }

.fa-smog:before {
  content: "\f75f"; }

.fa-smoking:before {
  content: "\f48d"; }

.fa-smoking-ban:before {
  content: "\f54d"; }

.fa-sms:before {


{
  content: "\f1eb"; }

.fa-wikipedia-w:before {
  content: "\f266"; }

.fa-wind:before {
  content: "\f72e"; }

.fa-window-close:before {
  content: "\f410"; }

.fa-window-maximize:before {
  content: "\f2d0"; }

.fa-window-minimize:before {
  content: "\f2d1"; }

.fa-window-restore:before {
  content: "\f2d2"; }

.fa-windows:before {
  content: "\f17a"; }

.fa-wine-bottle:before {
  content: "\f72f"; }

.fa-wine-glass:before {
  content: "\f4e3"; }

.fa-wine-glass-alt:before {
  content: "\f5ce"; }

.fa-wix:before {
  content: "\f5cf"; }

.fa-wizards-of-the-coast:before {
  content: "\f730"; }

.fa-wolf-pack-battalion:before {
  content: "\f514"; }

.fa-won-sign:before {
  content: "\f159"; }

.fa-wordpress:before {
  content: "\f19a"; }

.fa-wordpress-simple:before {
  content: "\f411"; }

.fa-wpbeginner:before {
  content: "\f297"; }

.fa-wpexplorer:before {
  content: "\f2de"; }

.fa-wpforms:before {
  content: "\f298"; }

.fa-wpressr:before {
  content: "\f3e4"; }

.fa-wrench:before {
  content: "\f0ad"; }

.fa-x-ray:before {
  content: "\f497"; }

.fa-xbox:before {
  content: "\f412"; }

.fa-xing:before {
  content: "\f168"; }

.fa-xing-square:before {
  content:the general assumption that the structural properties of the inherent states are indicative in some quantitative way of the dynamics of the supercooled configurations from which they are mapped.

A clear advantage of analyzing the structure of glassy inherent states over equilibrium configurations is the ability to cleanly and quickly extract structural observables while avoiding the difficulties that stem from thermal-fluctuations-induced noise, and from the broad spectrum of relaxation times that characterizes these systems. Instantaneous quenches are considered to be unrealistic idealizations of the physical cooling process by which glasses are formed. However, it is regularly assumed that *generic* properties of the resulting glasses remain unaffected by such protocols. This uncontrolled assumption overlooks the potential physical artifacts involved in performing instantaneous quenches in computational studies of the structural properties