Trek

Hike on unspoiled Inca Trails through the stunning remote Andean scenery away from other tourists, on our exclusive Wild Andes Inca Trek. If you choose this option you will get a small refund from kitty.

Option 2 - Classic Trek

Trek the Classic Inca Trail up the Royal Inca Road. Your kitty has been budgeted to accommodate for this option as it is the most costly of the 3 options.

Option 3 - Train Package (non-trekking option)

Relax in Cuzco and take the train to Machu Picchu without trekking. If you choose this option you will get a substantial refund from kitty.

Important note: You must advise us at the time of booking if you wish to book the Classic Inca Trail or the Train Package (non-trekking option), otherwise you will automatically behost communities we travel through, by supporting education, income generation and environmental sustainability projects. The trek itself is about the same as the Classic Inca Trail in terms of length and difficulty, taking three to three and a half days and ascending to about 4,700m when you cross the highest pass. The scenery out here is truly magnificent, spectacular mountain peaks, verdant hillsides dotted by isolated villages and the odd llama and alapaca, you are unlikely to see another tourist here. Although you won't trek into Machu Picchu via the Sun Gate as on the Classic Trail, you will arrive to Machu Picchu well rested after a night in a comfortable hotel and ready to get the most out of the tour of this magnificent site.

Accommodation

Camping (with facilities)


as they swoop around the canyon walls.

Accommodation

Hotel (1 night)

Meals Included

This morning we will head out on a short drive to some of the best viewpoints along the spectacular Colca Canyon, one of the deepest canyons in the world! The canyon is famous for its resident condors, and we will spend a good amount of time at the viewpoints to give ourselves the best chance of spotting them. We will also visit a couple of local communities on the way back to Chivay.

After lunch in Chivay, we will drive to the beautiful ‘White City’ of Arequipa.

In Arequipa we will stay in a good local hotel.

Estimated Drive Time - 4-5 hours

INCLUDED ACTIVITIES

Visit the phenomenal Colca Conyon and search for the native Andean Condors that fly through its spectacular scenery :in the beautiful deserts : USD 60

About Huacachina:
Huacachina is a sparkling oasis nestled in the deserts near Ica in northern Peru - an area that is more reminiscent of the Sahara than South America! The picturesque lagoon is surrounded by palm trees and towering sand dunes and creates a tranquil oasis in the dusty coastal desert. The small town here has become a popular destination for travellers due to its incredible sand boarding and dune bugging opportunities.

Accommodation

Included Activities

Meals Included

Today we will drive the short distance to Paracas and board one of the local boats for an included trip to the Ballestas Islands to view its incredible array of resident wildlife and birds.

After lunch, we will continue north to arrive at the chaotic Peruvian capital of Lima.

In Lima we


a very popular spot with the locals : USD 3

Explore the stunning gorges, forests, and landscapes of the Baños area by foot, possibly trekking the Machay River trail or visiting the nearby waterfalls of Pailon del Diablo and Machay : Free

Take the famous zip-lining course through the Puntzan Canyon near Baños, flying through the forest canopy and past several waterfalls : USD 20

Go out on a half day rock climbing trip to the walls of natural lava rock just outside Banos, which have routes suitable for people of all levels : USD 30

Take out some quad bikes on a tour around the winding trails near Baños : USD 36

Head out on a horse riding trip through the beautiful volcanic landscapes surrounding Baños : USD 40

Head out for anedge of the Amazon basin near the town of Tena, where we head to our jungle lodge for an incredible 3-night stay.

In the Ecuadorian Amazon we will stay in a comfortable rain forest lodge with meals included.

Estimated Drive Time - 3-4 hours.

About Ecuadorian Amazon:
The eastern part of Ecuador consists largely of tropical moist broad leaf forests that cover the lower slopes of the Andes and spill down into the Amazon Basin. The upland rain forest is strikingly different to that which is found in the lower basin, and features steep, rugged ridges and cascading streams and waterfalls. From our lodge near the city of Tena, we will explore these upland forests on foot and by boat - we'll aim to find various waterfalls, caves and creeks in the


forest, all the while keeping an eye out for the area's elusive wildlife. We'll also visit a local Quichua community during our stay in the forest lodge.

Accommodation

Lodge (1 night)

Meals Included

Over the next two days we will head into the Amazon jungle, enjoying rain forest treks exploring the nearby waterfalls and caves, and trips down the Napo River in motorised dugout canoes, hopefully spotting plenty of wildlife on the way. We will also see some ancient fossils and petroglyphs, and visit a local Quichua community.

INCLUDED ACTIVITIES

Spend 3 nights at our fantastic Ecuadorian rain forest lodge, taking in many activities such as boat trips on the Napo River, visits to local Quichua communities and treks through the jungle to some spectacular waterfalls and bat caves! : Included in Kitty

Accommodation

Lodge (1and Kushner are trying to use Gorelick’s credibility to help them disguise what is a patently nepotistic status in the government. Why would Gorelick, or really any decent person, allow themselves to be used by these people?

I think the answer is: this is what lawyers do. Jamie Gorelick, Sheri Dillon, they have paying clients. When you have clients, you work on their behalf. That’s the job. Lawyers are kind of like prostitutes — no offense to prostitutes — you pay them, and they do what you want. They serve an important, and dare I say honorable, role in society. It’s not always pretty, but if you need them they are there for you, provided you can pay the fee.

Moreover, good luck hiring a firm like Morgan Lewis or


of international matches remaining before the World Cup, Löw emphasized that it's on the players to remain fit and prepare themselves for the tournament. "Everyone has to get themselves ready and have the hunger that this tournament needs."gave me sleepless nights," he admitted. "David Lloyd (the former England and Lancashire coach) once told me never to put my helmet on until I got to the batting square."

I took wickets and everybody was celebrating around me and I just felt nothing, absolutely nothing.
Flintoff on his depression

"Let them see your eyes. Walk out as if you own the place. And that’s what I always did. The truth is that I never felt like I owned anything. It was all an act. I was just scared."

It was, however, only in retirement that Flintoff realised he may suffer from the condition. After presenting a BBC documentary on depression in sports stars in 2012, Flintoff approached his own doctor.

"During that filming what I already knew deep down became very


Q:

How to link parse customer to Stripe customer

I am using Stripe and Parse cloud service to charge a card. Charging is all fine, but I don't know which user made the purchase.  My application requires user to log in via Parse user to make the purchase.
I want to know
1. how can I create a Stripe customer using parse cloud code (JS).
2. how can I link that Stripe customer to the customer currently logged into my application (e.g [PFUser currentUser] from parse).
right now I have a vc to add credit card
[[STPAPIClient sharedClient] createTokenWithCard:stripeCard
                                 – the cleanliness, layout, lighting, ventilation and other facilities

how the business manages what it does to make sure food is safe and so that the officer can be confident standards will be maintained in the future

WHAT THE RATINGS MEAN:

0 - Urgent improvement necessary

1 - Major improvement necessary

2 - Improvement necessary

3 - Generally satisfactory

4 - Good

5 - Very good

Inspections take place throughout the year and ratings are subject to change.

Have you eaten at these establishments?

Leave your reviews in the comment section below.

Have you got our free app? Download it to keep up to date with all the latest news, sport and what's on stories. On iOS? download here or for Android click here


after order, which was dealt with very efficiently. The bears have arrived really quickly and they're perfect and very good quality. Thank you so much for an exceptionally good service and product.

Bears4U Customer Review by

Catherine Miller
location Warwickdate 17/08/2017

5.00out of five

I was thrilled with the bear I ordered as a gift for a friends new baby. The quality is amazing and the service was flawless. I definitely recommend this company, it's not the first bear I have ordered, nor will it be the last!

Bears4U Customer Review by

Mrs k arnold
location Westgate-on-seadate 03/07/2017

5.00out of five

Over at least the last 10 years I have ordered personalised bears for all of our grandchildren. I have always found the website quick and easy to use. The bear is always delivered in the time stateduntil a judgment is signed the judge may change his mind and sign a different judgment.
(Footnote omitted.)
We agree with the Michigan court. The effect of the nunc *911 pro tunc decree was to cut off petitioner's inheritance rights. Regardless of the apparent equities which favor the respondents, there was no second marriage involved and, therefore, no public policy served by entering the decree nunc pro tunc. See In re Marriage of Frapwell, 53 Cal. App.3d 479, 125 Cal. Rptr. 878 (1975). Moreover, the decree did not merely correct a ministerial or clerical error. As we have stated:
[A motion nunc pro tunc] may be used to make the record speak the truth, but not to make it speak what it did not speak but ought to have spoken. If


decree nunc pro tunc.
With respect to (a), since, as Hume observed, the future can never be predicted, our expectation that the future will be like the past (e.g., that the sun will rise tomorrow morning) has no basis in reason; it is purely a matter of belief. Hume also asserted, however, that such theoretical skepticism is irrelevant to the practical concerns of daily life. See Hume, "An Enquiry Concerning Human Understanding", in 35 Great Books of the Western World 451, 469, § 6  Of Probability (1952). Such is the case here. The record is clear: There was full agreement the final papers  findings, conclusions, and decree  would be signed on Monday. The litigation was over; this court should not now indulge a hypertechnical reluctance butinvolved in the representation of Mrs. Pratt at trial, however. Any questionable conduct in delaying entry of the dissolution decree is attributable solely to Mrs. Pratt's trial counsel.
[2]  Under RCW 11.04.015, if Nadine Pratt were considered married at the time of her husband's death, then as his surviving spouse, she would inherit one-half of his separate property. If, however, the decree of dissolution is given effect as of March 31, 1980, then Mr. Pratt's entire estate would pass to his children. At the time of his death, Mr. Pratt owned separate property worth approximately $70,000.


simplicity of a device.
A connector shape, layout of terminals, and terminal functions are prescribed by the data communication standards. Some of the data communication standards do not stipulate that a connector should be furnished with a power supply input terminal. If no power is supplied from a main apparatus to a wireless communication module, a power supply or a power cable should be additionally provided to the wireless communication module. In such cases, usability of the wireless communication module is lowered.
For example, Japanese Utility Model Registration Application No. 2003-2702 discloses a relay connector for connecting between an external device and a main apparatus based on serial ATA standards. In the relay connector conforming to the serial ATA standards, a signal section and a power supply section are physicallycaregivers who had CD and those that were not diagnosed with CD did not differ.

It is important to mention that the answers to two of the sociodemographic questions, items 15 and 16, were not presented in [Table 2](#nutrients-11-02302-t002){ref-type="table"} since item 15 "Do you prepare GF meals at home?", and 16 "Was the CD of your child or adolescent diagnosed by a doctor?" did not present variability in the responses (absolute agreement was 95%), therefore, those were not considered statistically significant (*p* \< 0.05). It is also important to highlight that our sample size was relatively small, 150 individuals, and the variables that presented as \< 150 indicate missing sociodemographic data, where the participant did not mark any response in the item of the questionnaire.

4. Discussion {#sec4-nutrients-11-02302}
=============

According to the


and governmental institutions in developing effective strategies to improve the QoL of celiac children and adolescents, and consequently, the QoL of Brazilian parents or caregivers.

We would like to thank the parents and caregivers of CD patients who took the time to answer our questionnaire. We would also like to thank all the specialists who participated in the validation process.

######

Click here for additional data file.

The following are available online at <https://www.mdpi.com/2072-6643/11/10/2302/s1>, Table S1: Celiac Disease Patents of Children or Adolescents Quality of Life Questionnaire (CDPCA-QoL)--The Brazilian-Portuguese version Questionário de doença celíaca (QCD)--índice relacionado a qualidade de vida dos pais ou responsáveis de crianças e adolescentes portadores de doença celíaca, Table S2: Celiac Disease Patents of Children or Adolescents Quality of Life Questionnaire (CDPCA-QoL)--The English version.

Conceptualization, L.M.A.P., L.G., R.H.U.,          38.06 (7.73) ^A^    25.69 (7.78) ^A,B^     38.77 (8.85) ^A^   102.52 (21.54) ^A^
  Graduate or above (*n =* 49)                                                                          37.63 (7.69) ^A^    28.12 (8.82) ^B^       37.94 (7.87)


Q:

Blazor Textfield Oninput User Typing Delay

How can I add a delay to an event (OnInput) in Blazor ?For example, if a user is typing in the text field and you want to wait until the user has finished typing.
Blazor.Templates::3.0.0-preview8.19405.7
Code:
@page "/"
<input type="text" @bind="Data" @oninput="OnInputHandler"/>
<p>@Data</p>

@code {
    public string Data { get; set; }

    public void OnInputHandler(UIChangeEventArgs e)
    {
        Data = e.Value.ToString();
    }
}

A:

Solution:
There is no single solution to your question. The following code is just one approach. Take a look and adapt it to your requirements. The code resets a timer on each keyup, only last timerSaid’s detentions. The lifting of the order led to reports in the Israeli media on Monday that the arrests of both men related to accusations of spying and contact with a foreign agent from Lebanese group Hizbullah. Ameer Makhoul has been the General Director of Ittijah, which works on behalf of the Palestinian community in Israel, since its foundation in 1995. He is also the chair of the Public Committee for the Defence of Political Freedom within the Arab Higher Monitoring Committee in Israel. "In the unlikely event that there are genuine grounds to prosecute Ameer Makhoul he should be charged with recognizable criminal offences and brought promptly to trial in full conformity with international fair trial standards," said Philip Luther.


to a disadvantageous heat production. The high energy requirement is a considerable disadvantage in particular in portable or mobile systems respectively, since systems of this kind are usually supplied by batteries. Also in regard to situations in which the heart-lung machine can be operated only with emergency power it is desirable to keep the current requirement as low as possible. In addition, such electromagnetically operated clamping apparatuses also have the disadvantage that they can not be opened or closed manually when the electrical system fails.
Starting from this prior art, an object of the invention is therefore to propose a clamping apparatus for clamping off a hose in a fluid system for biological liquids which does not have these disadvantages. In particular the clamping apparatus should require as littleof merging the metadata and"
" formats of two or more book records. You can choose to either delete or "
"keep the records that were not clicked first."
msgstr "**Bucheinträge zusammenführen**: Diese Option gibt Ihnen die Möglichkeit Metadaten und Formate von zwei oder mehr Büchern zusammenzuführen. Die Datensätze der Büchern, die nicht zuerst angeklickt wurden, entweder löschen oder behalten."

#: ../../home/kovid/work/calibre/manual/gui.rst:87
msgid "For more details see :ref:`metadata`."
msgstr "Für weitere Details siehe :ref:`metadata`."

#: ../../home/kovid/work/calibre/manual/gui.rst:92
msgid "Convert books"
msgstr "Bücher konvertieren"

#: ../../home/kovid/work/calibre/manual/gui.rst:96
msgid ""
"|cei| E-books can be converted from a number of formats into whatever format"
" your e-book reader prefers. Many e-books available for purchase will be "
"protected by :doc:`Digital Rights Management <drm>` *(DRM)* technology. "
"calibre will not convert these e-books. It is easy to remove the DRM from "
"many formats, but as this may be illegal,


once to convert a "
"number of e-books in bulk."
msgstr "**Mehrere gleichzeitig konvertieren**: Sie können die Optionen der Konvertierung einmalig für alle ausgewählte eBooks anpassen und dann alle auf einmal konvertieren."

#: ../../home/kovid/work/calibre/manual/gui.rst:109
msgid ""
"**Create a catalog of the books in your calibre library**: Allows you to "
"generate a complete listing of the books in your library, including all "
"metadata, in several formats such as XML, CSV, BiBTeX, EPUB and MOBI. The "
"catalog will contain all the books currently showing in the library view. "
"This allows you to use the search features to limit the books to be "
"catalogued. In addition, if you select multiple books using the mouse, only "
"those books will be added to the catalog. If you generate the catalog in an "
"e-book format such as EPUB, MOBIbe re-imported to the library without any loss of information by using "
"the :ref:`Add books <add_books>` action."
msgstr "Für 1. und 2. werden für jedes ausgewählte Buch alle verfügbaren Formate sowie Metadaten auf Datenträger gespeichert. Metadaten werden in einer OPF-Datei gespeichert. Gespeicherte Bücher können erneut ohne Verlust an Informationen in die Bibliothek mithilfe der Aktion :ref:`Bücher hinzufügen <add_books>` importiert werden."

#: ../../home/kovid/work/calibre/manual/gui.rst:229
msgid ""
"**Save only *<your preferred>* format to disk**: Saves the selected books to"
" disk in the directory structure as shown in (1.) but only in your preferred"
" e-book format. You can set your preferred format in "
":guilabel:`Preferences->Interface->Behaviour->Preferred output format`"
msgstr ""

#: ../../home/kovid/work/calibre/manual/gui.rst:231
msgid ""
"**Save only *<your preferred>* format to disk in a single directory**: Saves"
" the selected books to disk in a single directory but only in your preferred"
" e-book format.


preferences at :guilabel:`Preferences->Sharing->Sharing over the "
"net`"
msgstr ""

#: ../../home/kovid/work/calibre/manual/gui.rst:250
msgid ""
"**Setup email based sharing of books**: Allows sharing of books and news "
"feeds by email.  After setting up email addresses for this option, calibre "
"will send news updates and book updates to the entered email addresses. You "
"can configure how calibre sends email by setting preferences at "
":guilabel:`Preferences->Sharing->Sharing books by email`. Once you have set "
"up one or more email addresses, this menu entry will be replaced by menu "
"entries to send books to the configured email addresses."
msgstr "**E-Mail-Versand von Büchern einrichten**: Ermöglicht den Austausch von Büchern und Newsfeeds per E-Mail. Nach der Einrichtung von E-Mail-Adressen für diese Option sendet Calibre Nachrichten und Buchaktualisierungen an die eingegebene E-Mail-Adressen. Wie Calibre E-Mails versendet, wird über :guilabel:`Einstellungen → Versand → Bücherversandthe tags `A.B` and `A.B.C`, but not the tag "
"`A`."
msgstr "Hierarchische Elemente (z. B. A.B.C) verwenden eine erweiterte Syntax, um erste Teile der Hierarchie zu finden. Dies erfolgt durch Hinzufügen eines Punktes zwischen dem Gleichheits-Indikator (=) und dem zu suchenden Text. So findet z. B. die Abfrage ``tags:=.A`` die Tags `A` und `A.B`, aber nicht die Tags `AA` oder `AA.B`. Die Abfrage ``tags:=.A.B`` finden die Tags `A.B` and `A.B.C`, aber nicht das Tag `A`."

#: ../../home/kovid/work/calibre/manual/gui.rst:423
msgid ""
"Identifiers (e.g., ISBN, doi, lccn etc) also use an extended syntax. First, "
"note that an identifier has the form ``type:value``, as in "
"``isbn:123456789``. The extended syntax permits you to specify independently"
" which type and value to search for. Both the type and the value parts of "
"the query can use `equality`, `contains`, or


"
"them to that category. If the source is a User category, holding the shift "
"key while dragging will move the item to the new category. You can also drag"
" and drop books from the book list onto items in the Tag browser; dropping a"
" book on an item causes that item to be automatically applied to the dropped"
" books. For example, dragging a book onto Isaac Asimov will set the author "
"of that book to Isaac Asimov. Dropping it onto the tag History will add the "
"tag History to the book's tags."
msgstr ""

#: ../../home/kovid/work/calibre/manual/gui.rst:559
msgid ""
"You can easily find any item in the Tag browser by clicking the search "
"button at the lower-right corner. In addition, you can right click on any "
"item and choose one of several operations.if you prefer to browse your collection by covers instead. The "
":guilabel:`Cover grid` is activated by clicking the :guilabel:`Layout` "
"button in the bottom right corner of the main calibre window. You can "
"customize the cover sizes and the background of the :guilabel:`Cover grid` "
"via :guilabel:`Preferences->Interface->Look & feel->Cover grid`. You can "
"even have calibre display any specified field under the covers, such as "
"title or authors or rating or a custom column of your own devising."
msgstr ""

#: ../../home/kovid/work/calibre/manual/gui.rst:583
msgid "Cover browser"
msgstr "Titelbildbrowser"

#: ../../home/kovid/work/calibre/manual/gui.rst:588
msgid ""
"In addition to the :guilabel:`Cover grid` described above, you can also have"
" calibre display covers in the single row. This is activated via the "
":guilabel:`Layout` button in the lower right corner of the main window. In "
":guilabel:`Preferences->Interface->Look & feel->Cover browser` you can "
"change the number of covers


legal ownership of the term Neuro-Linguistic Programming (NLP); however, it was eventually deemed to be a generic term, and could therefore not be trademarked. Grinder and Bandler settled their claims around 2001, clearing a platform for the future development of NLP as a legitimate field of endeavor.

New code of NLP

Between 1982 and 1987, strongly influenced by anthropologist and systems theorist Gregory Bateson, who had a strong focus on ecology as a psychological construct, Grinder and Judith DeLozier collaborated to develop the "New Code of NLP". (Grinder and Bateson had met during their affiliation with Kresge College at the University of California, Santa Cruz during the 1970s.) Grinder and Delozier presented an aesthetic framework for the "classic code" of NLP that explicates the involvement of ecology and the unconscioussee
how we can ask for suitably anonymized data…

Thanks to a conversation earlier about web development and careers, I
think I’ve figured out a little more about what I want to do. =)

I want to support people and communities through social tools.

I want to help people make the most of blogs, wikis, podcasts,
vidcasts, social bookmarking, social networking, community content
management systems, whatever. I want to help them figure out how to
use version control systems and request trackers and mailing lists. I
want to make it easier to use phone and e-mail and little stickies on
the fridge…

What should I learn more about? I need to figure out how to set up a
blog farm, a wiki farm, a social bookmarking site, Drupal, etc. Bryght
does hosted community sites with Drupal, so they’d be good mentors


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![](yjbm00512-0067.tif "scanned-page"){.400}

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![](yjbm00512-0069.tif "scanned-page"){.402}

[^1]: From the Department of Obstetrics and Gynecology, Yale University School of Medicine.
Novel hierarchical Sn3O4/BiOX (X = Cl, Br, I) p-n heterostructures with enhanced photocatalytic activity under simulated solar light irradiation.
Sn3O4/BiOX (X = Cl, Br, I), a series of p-n-heterojunction-based photocatalysts, were prepared by a combination of an ultrasonic-assisted precipitation-deposition method and hydrothermal method. The photodegradation of Rhodamine B among all the materials, under simulated solar light irradiation, was investigated in detail. The photocatalyst test showed that the novel composite, Sn3O4/BiOCl, was able to degrade 99% of Rhodamine B (RhB) and its intermediates in 9 minutes, which is faster than Sn3O4/BiOBr (21 min) and Sn3O4/BiOI (12 min). Moreover, the degradation rate of RhB for Sn3O4/BiOCl samples (Sn : Bi = 1/4) was the highest, about 99%, slightly higher than that of Sn3O4/BiOCl-1/8 (95%), which was significantly higher than those of


 //                 method and only constructing when valid.
  std::unique_ptr<HttpAuthHandler> tmp_handler(
      new HttpAuthHandlerNTLM(sspi_library_.get(), http_auth_preferences()));
  if (!tmp_handler->InitFromChallenge(challenge, target, ssl_info,
                                      network_isolation_key, origin, net_log))
    return ERR_INVALID_RESPONSE;
  handler->swap(tmp_handler);
  return OK;
}

HttpAuthHandlerNTLM::HttpAuthHandlerNTLM(
    SSPILibrary* sspi_library,
    const HttpAuthPreferences* http_auth_preferences)
    : mechanism_(sspi_library, HttpAuth::AUTH_SCHEME_NTLM),
      http_auth_preferences_(http_auth_preferences) {}

int HttpAuthHandlerNTLM::GenerateAuthTokenImpl(
    const AuthCredentials* credentials,
    const HttpRequestInfo* request,
 lending.” Twelve states have even banned payday loans altogether. Caution should be taken when considering obtaining these types of loans, which often “rollover” or are extended when they can’t be repaid in time and result in additional extension fees and an overall larger repayment amount. Because of the risk, payday loans should only be used in emergency situations when you know you can pay the loan back in full on time. If you do not borrow, you could end up in more debt.
In AK, AZ, DC, FL, HI, IN, KY, ME, MI, MN, MT, NE, ND, OK, OR, RI, SD, WA and WY all installment loans are originated by FinWise Bank, a Utah chartered bank, located in Sandy, Utah, member FDIC. California applicants may be funded by one


form online or in person in the loan store. Lenders generally process the applications immediately and get back with a decision in a few minutes. Depending on the lender, you will get the borrowed funds in a few hours or by the next business day.
4. Stay on top of your payments. Commit to a loan length that you know will work for your budget. For instance, if your loan length is three years, do the math and see if you can manage to pay it off in two. If there are no prepayment fees, you’ll save on the interest. However, if you can’t, your credit won’t be affected negatively and you’ll still be adhering to the terms of the loan.

Contact your creditors or loan servicer as quickly as"My name is Michael Westen." "I used to be a spy until..." "[Phone rings] We got a burn notice on you." "You're blacklisted." "[Whistles]" "When you're burned, you've got nothing." "No cash, no credit, no job history." "You're stuck in whatever city they decide to dump you in." " Where am I?" " Miami." "You do whatever work comes your way." "You rely on anyone who's still talking to you..." "[Laughs]" "A trigger-happy girlfriend..." "Should we shoot them?" "An old friend who used to inform on you to the FBI..." "You know spies-- bunch of bitchy little girls." "Family too..." "[Phone rings] Hey, is that your mom again?" "If you're desperate." "Someone needs your help, Michael." "And a down-and-out spy you met along the way." "That's how we


do it, people." "Bottom line, as long as you're burned, you're not going anywhere." "This is the only offer you will get." "We're going after the leader of a terrorist network based in the Dominican Republic." " Burke." " I got a job coming up." "I was hoping you might be right for it." "I'll be in touch, but I want you to keep a low profile until I get back." "And be ready." "Michael Westen was still working for the CIA." "You are going to put me in touch with him." "Fi, it's time to be brave, little angel." "[Gunfire]" "[Radio chatter]" "For spies, the hardest part of operating in the field isn't combat." "When bullets are flying, there's never really time to think." "But in theone, but two international terrorists," "I can't afford any mistakes when your friends start playing deep cover." "They'll be fine." "Here comes Porter, at the buzzer for the win." "It's up!" "He's good!" "[Laughs]" "Mr. Axe, wanna get spanked, a little one-on-one?" "No, I'm good." "Your secretary told me you'd be here." "So shooting hoops at 11:00 a.m." "Must be nice." " I'm working, brother." " Are you?" "You see that dumpy little drug den over there?" "My target's about to roll up in a yellow Porsche." "Think you can put your job on hold?" "For what?" "Well, remember when we told Mike we'd help him out?" " Yeah." " I just got a call." " Where is he?" " Dominican Republic." "He wasn't very forthcoming with details,


but he needs backup." "Look, Sam, you know I want to help Mike out, but I got clients to answer to, man." "I can't just go running off to the D.R." "on a random Thursday." "Tell me about it." "I was supposed to go have some extra special Sammy time with Elsa this weekend, but that ain't happening." "I guess this is serious." "Look, Jesse, it's either gonna be us going or me going." "I'm not gonna leave him hanging." "Okay." "It's gonna have to wait until tomorrow, though." "It can't." "It's gotta be today." "That's not even possible." "Fake passports don't just magically appear." "We don't need them." "The CIA's getting us a dark plane." " Wow." " Strong's gonna brief us at the airport in onescared." "Please." "I'm worried Charlie's gonna get hurt." "Yeah, well, someone's gonna get hurt." "It won't be Charlie." "There are many advantages to flying into a country on an unregistered plane." "You don't wait in lines, you don't check bags, and you don't leave an incriminating paper trail." "The disadvantage is that without a declared flight path, you can't land at an airport." "So the best you can hope for is finding an open field and flying in low." " You see them?" " Yeah, they're headed our way." "Of course, while flying in low might keep you off the radar of the local authorities, it also means you're a lot easier to spot from the ground." "[Speaking Spanish on radio]" " We have a problem." " What's


you said it, brother." "I think I figured out how to get rid of this Sapienza guy." "How?" "If you pooled together all your valuables, how much would you have?" "In my savings account, $24,000, plus an additional $8,000 or $10,000 if I include my jewelry." "Great." "We're gonna need all that." "Do you still have that silver pendant necklace?" "Yeah." "It was my mom's favorite." " I'm gonna need that too." " Fiona, what is this?" "Criminals can't keep their money in a bank." "They have to keep it in a safe or a lockbox somewhere, so we give this Sapienza guy something to squirrel away, and then we find his stash, and we take it." " And then?" " Mafia bookies-- they're only powerful if they"Go!" "Are you okay?" "Yeah." "Yeah, I'm fine." "Just got word from Westen." "He's securing this warehouse and the surrounding area tomorrow." "Looks like Burke's in a hurry to make this sale happen." "I want snipers in these windows here and on those rooftops there." "Westen's gonna be wired for sound, we're gonna know when the deal is done." "Special Forces are gonna work in two capture teams to sweep up Serano and Burke as they try to drive away." "Are there any questions?" "Um, I have a question." "What are we supposed to be doing?" "Well, first, you're gonna be fully briefing my men on Burke, and then you're gonna catch a boat back to Miami." "Yeah, um..." "That ain't happening, pal." "I'm sorry." "What "ain't happening"?"


one of those sniper teams to take out Serano and Burke before they even get there." "It's not happening." "Langley wants a recording of this deal, so guess what Langley's gonna get." "We have a confirmed visual on Burke." "Repeat, a confirmed visual on Burke." "Okay." "Good talk." "Time for me to work." "[Background chatter]" "All right, everyone, we're on." "When was your last perimeter sweep?" " 15 minutes ago, all clear." " Good." "Burke, I know this isn't great timing, but I'm concerned about the exit routes, this location." "If there's any way to push the timeline" "Too late for that, man." "It's on." "I understand you're concerned, but I picked this place for a reason, Mike." "I don't even know who we're meeting with." "Oh, I'myou." "And now you're gonna hear me." "I know why you're sweating, and I know why you're wearing a gun today." "Lose something?" "You?" "So here's how this is gonna go." "You're gonna do exactly as I say, because if you don't, you're gonna be explaining to your powerful friends how a woman old enough to be your mother managed to steal your safe." "I thought I'd only find money in there, but I did a lot better than that." "Your entire client list." "There's enough information in there to put you out of business, in jail, and maybe even in a very early grave." "You can go ahead and keep that 'cause I made a copy for myself." "All right, I made some others for my powerful


It identifies what is known so far, suggests key questions for future research, and highlights some potential differences in the relationship between the built environment and physical activity in China compared to research findings from developed countries.

2. Methods {#s0010}
==========

This paper reviews 42 published empirical studies on physical activity and the built environment in China. The paper is modeled closely on a paper by [@bb0200]. [@bb0200] are widely cited---701 times as of July 6, 2015, according to Google Scholar. [@bb0200] reviewed 13 published literature reviews and 29 empirical research reports on the association between walking and the built environment. Their paper offers a systemic framework for analysis of literature that is replicable and that, importantly, allows for comparison with the present review. [@bb0200] review provides a guide for thesame street could potentially vary in their micro-environments. Meso environments included the small scale environments in which an individual lives, such as a neighborhood or census block group. Macro-environments were the larger scale environments in which an individual lives, such as the city or county. All individuals within that scale are considered to have the same environment.

The review also identified the type(s) of physical activity measured (recreation, transportation, work, and/or general); and whether results were expected, unexpected, and null. Expectedness was based on prior empirical research and conceptual models on the relationship between the built environment and physical activity. "More" of the following built environment factors were expected to be associated with more physical activity: density; proximity to nonresidential land uses (includes mixed land uses, transit access); street


(not specified)/survey or interview                                   Demos                                         \(1\) Residents of urban areas more likely to be active during leisure time compared to rural populations. (2) Residents of urban areas were less likely to be active in work, compared to rural population (3) Men living in urban areas engage in less walking or cycling for commuting, compared Demos                                         \(1\) Shops near home, transit stops near home, sidewalks, bicycling facilities, and free or low cost recreational facilities associated with higher odds of meeting physical activity recommendations. (2) Crime-related safety associated with lower odds of meeting physical activity recommendations.
  [@bb0090]   China


Transportation/survey or interview                                            None                                          \(1\) Shorter distance associated with increased likelihood of active travel. (2) Increased distance to rail station associated with decreased probability of walking, bicycling to transit station. (3) Living closer                                       Demos, other                                  \(1\) In higher density and higher jobs-housing balance areas, probability of choosing walking, cycling or another mode of transit is higher than choosing public transit. (2) In areas with high density and high jobs-housing balance, probability of choosing walking, cycling or another mode of transit is higher than probability of commuting by car.


{
			var field_value = ( jQuery.isArray( live_field_value ) && live_field_value.length === 1 ) ? live_field_value[0] : live_field_value;
			if ( condition.value === field_value && um_in_array( field_value, $owners_values[ condition.owner ] ) ) {
				$owners[ condition.owner ][ index ] = true;
			} else {
				$owners[ condition.owner ][ index ] = false;
			}
		}

		if ( condition.operator === 'not equals' ) {
			var field_value = ( jQuery.isArray( live_field_value ) && live_field_value.length === 1 ) ? live_field_value[0] : live_field_value;
			if ( jQuery.isNumeric(condition.value) && parseInt(field_value) !== parseInt( condition.value ) && field_value && ! um_in_array( field_value, $owners_values[ condition.owner ] ) ) {
				$owners[ condition.owner ][ index ] = true;
			} else if ( condition.value != field_value && ! um_in_array( field_value, $owners_values[ condition.owner ] ) ) {
				$owners[ condition.owner ][ index ] = true;
			} else {
				$owners[ condition.owner ][ index ] = false;
			}
		}

		if ( condition.operator === 'greater than' ) {
			varMayor Emo?) The Doctor didn't actually claim the presidency until a year later, when he decided the best way to prevent an invasion of Gallifrey was by helping the invaders take over, and THEN defeating them. Despite being the only president to turn his inauguration into a party for marauding tinfoil monsters, the Doctor was popular enough that the Gallifreyans begged him to take office again.

Brainwash everybody in the country via telepathic satellite. It worked for the Master, the Doctor's nemesis, on Doctor Who. Maybe because the Master was so impressed by the Doctor's election-stealing prowess, the Master stepped up his game and got himself elected Prime Minister of Great Britain, thanks to the Archangel satellite network broadcasting pro-Master messages into people's brains.

Advertisement

Brainwash everybody in the country via


The comparative psychophysics of complex shape perception.
The authors compared the complex shape perception of humans and monkeys. Members of both species participated in a Same-Different paradigm in which they judged the similarity of shape pairs that could be variations of the same underlying prototype. For both species, similarity gradients were found to be steep going out from the transformational center of psychological space. In contrast, similarity gradients were found to be flat going from the periphery in toward the center of psychological space. These results show that there are important common principles in the shape-perception and shape-comparison processes of humans and monkeys. The same general organization of psychological space is obtained. The same quantifiable metric of psychological distance is applied. Established methods for creating controlled shape variation haveSACRAMENTO, Calif. (Reuters) - Democrats seeking to unseat Republican U.S. President Donald Trump in 2020 will choose from the largest and most diverse set of candidates in history - yet, so far, two older white men are leading the pack.

FILE PHOTO: Twenty four 2020 Democratic presidential candidates are seen in a combination from file photos (L-R top row): U.S. Senators Bernie Sanders, Kamala Harris, Elizabeth Warren, Cory Booker, Amy Klobuchar, Kirsten Gillibrand, Michael Bennet and former U.S. Senator Mike Gravel. (L-R middle row): Former Texas congressman Beto O'Rourke, U.S. Representatives Tulsi Gabbard, John Delaney, Eric Swalwell, Tim Ryan, Seth Moulton, former HUD Secretary Julian Castro and former U.S. Vice President Joe Biden. (L-R bottom row): Mayor Pete Buttigieg, Former Gov. John Hickenlooper, Gov. Jay Inslee, Andrew Yang, Marianne


or race.

Voter Aleia White, 32, agrees. She would prefer, however, that the eventual nominees for president and vice president reflect America’s diversity.

“It’s important that the ticket represent our country,” White said at a recent campaign event for Warren in Ohio. “We’re not all white men.”Summary: We hypothesize that skin microbiota (bacteria, fungi, viruses, phage, archae) plays a role in common dermatological conditions, such as atopic dermatitis (eczema). There are two classical explanations for how microbes might affect skin disease: (1) a specific microbe colonizes the skin to disrupt the balance of commensal microflora, or (2) a specific microbe releases toxic substances or invade cells to induce an inflammatory response directly. However, it is increasingly clear that bacteria flourish and compete within a larger microbial community. My laboratory developed clinical and laboratory methodologies to characterize skin microbial communities with genomic techniques, which offer significant advantages over traditional culture-based studies. We performed the first skin microbiome survey, characterizing the diversity of microbes that live on normal adult volunteers, and determined that humans are ecosystems


on extreme slopes under heavily loaded conditions.
In view of the above discussion, it can be appreciated that it would be desirable to have a prosthetic ankle that enables the user to adjust the flexion angle of the ankle to accommodate inclines and declines.and less winged wheel in the stands, now Nashville had tangible evidence that there was a transition happening.

Fast forward a year and a half and the Predators are continuing the effort. This time, however, due of the sudden explosion of Blackhawks fans that seem to have come out of the woodwork.

“If I said we were doing this plan five years ago, you would’ve said ‘Oh, for the Red Wings!’ of course,” Henry said. “When we played them in the playoffs, we kept the red out there. Why? A lot of their fans that live here really converted over.”

So Nashville is getting creative. This season, for the first time, you will not be allowed to buy single game tickets for the November 16, December 17 and April 12 home


(for the pre-sale) only those in the zip codes that we unlock can buy the Blackhawk game and a second game. So we’re breaking down every barrier we can to Keep the Red Out.”

That helps keep Chicago fans at bay, for sure. But what if Blackhawks fans really want to jump through hoops to see their team play in Music City?

“They’re going to have to earn it,” Henry said. “And they’re going to help us continue to grow our roster by building our (revenue at the) gate. It’s that simple. In the end, we’re building something pretty special. If we have to do it off the backs of their fans a little bit, I’m not apologizing for it.

“We don’t want to build those ticket grosses off of our     l = '/* ' + l[:m.end('name')] + ' */' + l[m.end('name'):]

            output.write(l)

    return {path, config.source}

def main(argv):
    parser = argparse.ArgumentParser(
        description='Process define files.')

    parser.add_argument('input', help='Input define file.')

    args = parser.parse_args(argv)

    return process_define_file(sys.stdout, args.input)

if __name__ == '__main__':
    sys.exit(main(sys.argv[1:]))


on dSNF^RRM1^/hU1A^RRM1^ is reflected in similar protein contacts to the 5′ branches of the RNA stems (Fig. [3c](#Fig3){ref-type="fig"}). However, molecular interactions in other parts of the complexes differ in detail. In the human system, the side chains of Ser46 and Ser48 together with backbone amides of Arg47 and Lys50 (L3) maintain an extensive, water-mediated hydrogen bonding network with nucleotides A12-G17 (Fig. [3d](#Fig3){ref-type="fig"}, bottom panel). In contrast in the *Drosophila* complex, the corresponding dSNF^RRM1^ residues (Leu43, Thr45, Lys44, and Lys47, respectively) do not allow the formation of a similarly extensive water network. While Thr45, Lys44, and Lys47 engage in water-mediated contacts to the phosphate oxygens of C16 and G17, a more expanded network is prevented by Leu43, which replaces Ser46 of hU1A^RRM1^ in dSNF^RRM1^ (Fig. [3d](#Fig3){ref-type="fig"}, top and middle panels). As aaffinity (Fig. [6b](#Fig6){ref-type="fig"}).

G13 of dU2^SLIV^ adopts a *syn* conformation to occupy an equivalent position as C13 of dU1^SLII^, sandwiched by A12 and Asp89 (α3) of dSNF^1-96^ and hydrogen bonding to the backbone amide of Asp89 (Fig. [6d](#Fig6){ref-type="fig"}). Mutational analysis showed that C13 in dU1^SLII^ and G13 in dU2^SLIV^ are critical determinants of RNA affinity and specificity. A dU2^SLIV^ variant bearing a G13A replacement lacks the ability to support the *syn* conformation by an interaction with its own phosphate and might additionally lose a contact to the Asp89 backbone, resulting in 200-fold reduced affinity to dSNF^1--101^ (Fig. [6b](#Fig6){ref-type="fig"}). Conversely, a dU1^SLII^-like G13C substitution in dU2^SLIV^ led to 16-fold higher affinity for dSNF^1-101^ (Fig. [6b](#Fig6){ref-type="fig"}), presumably due to the ability of cytidine at this position to additionally contact Asp87 (see above).

Significant differences compared to


dU1^SLII^ are again seen in the following 3′ sequence of the dU2^SLIV^ loop. U14 adopts the same position in both copies of the ternary complex, resembling the minor conformation of the equivalent C14 of the dSNF^1--96^--dU1^SLII^ complex, with the base occupying a binding pocket on dSNF^1--96^ (Fig. [6d](#Fig6){ref-type="fig"}, top and bottom panels). U14 of dU2^SLIV^ can engage in more complementary interactions than a cytidine at the equivalent position, with its Watson-Crick hydrogen bonding potential fully saturated by contacts to Lys20, Lys24 (α1) and the backbone carbonyl of Ala42 (L3; Fig. [6d](#Fig6){ref-type="fig"}, top panel). Thus, there are more extensive contacts of U14 in dU2^SLIV^ to dSNF^1--96^ helix α1 compared to C14 in dU1^SLII^. Consistently, a U14C substitution reduced dSNF^1--101^ affinity twofold (Fig. [6b](#Fig6){ref-type="fig"}). In addition, U14 is held in its position onAs another example, the cold shock domain of Upstream-of-N-ras (Unr) and two RRMs of the sex lethal (SXL) protein form an intimately intertwined complex, in which the RNA affinities and specificities of the proteins are mutually reprogrammed to specifically recognize an RNA element in the 3′ untranslated region of *msl2* mRNA during dosage compensation in *Drosophila*^[@CR25]^. Yet another case is afforded by the spliceosomal Snu13 and Prp31 proteins that recognize 5′ stem-loops in the major spliceosomal U4 and the minor spliceosomal U4atac snRNAs^[@CR26]^. Snu13 positions its αβα sandwich fold to bind kink-turns in the RNAs using the edge of a helix and sheet to contact residues that are identical in U4 and U4atac^[@CR27],\ [@CR28]^. In contrast, Prp31 uses a NOP domain to interact with Snu13 and with different


residues in the two RNAs^[@CR26],\ [@CR29]^. Different local structures in the capping pentaloops of the RNAs allow them to adapt differently to Prp31, resulting in different complex stabilities^[@CR26]^. Moreover, Snu13 also binds kink-turns in box C/D snoRNAs^[@CR30]^. However, in the latter case it is aided by different NOP domain proteins, NOP56/58^[@CR29],\ [@CR31]^. In all of the above cases, the cooperating proteins modulate their respective conformations and/or both proteins exhibit RNA contacts that are important for the stability of RNPs. Among the hundreds of RBPs^[@CR2],\ [@CR4],\ [@CR32]^, there are certain to be many others whose specificities are modulated through protein--protein interactions.

Here, we studied how the affinity of dSNF^RRM1^ for related RNA hairpin loops is modulated by the LRR domain of the dU2A' protein. We investigated structures and dynamics of      \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$$\Delta {\mathrm{R}}_{{\mathrm{2,eff}}} = - 1/{\mathrm{T}}_{{\mathrm{relax}}} \cdot {\mathbf{ln}}\left[ {{\mathrm{I}}\left( {{\mathbf{\nu }}_{{\mathrm{CPMG}}\;{\mathrm{at}}\;{\mathrm{1000Hz}}}} \right)/{\mathrm{I}}\left( {{\mathbf{\nu }}_{{\mathrm{CPMG}}\;{\mathrm{at}}\;{\mathrm{50Hz}}}} \right)} \right].$$\end{document}$$

Data availability {#Sec19}
-----------------

The coordinates and structure factor data have been deposited in the Protein Data Bank ([www.pdb.org](http://www.pdb.org)) with the accession codes [6F4I](https://doi.org/10.2210/pdb6F4I/pdb) (dSNF^1--96^), [6F4J](https://doi.org/10.2210/pdb6F4J/pdb) (dU2A′-dSNF^1--96^), [6F4H](https://doi.org/10.2210/pdb6F4H/pdb) (dSNF^1--96^--dU1^SLII^)


für Molekulare Medizin and the Leibniz-Institut für Molekulare Pharmakologie.

G.W., G.T.D., K.B.H. and M.C.W. designed experiments. G.W., G.T.D., N.H. and K.B.H. performed experiments. G.W., G.T.D., K.B.H. and M.C.W. wrote the manuscript.

Competing interests {#FPar1}
===================

The authors declare no competing interests.
  byte[] data = ResourceBuilder.Build(Fragment, 162); //yft is type/version 162...

            return data;
        }

    }

    public class YftXml : MetaXmlBase
    {

        public static string GetXml(YftFile yft, string outputFolder = "")
        {
            StringBuilder sb = new StringBuilder();
            sb.AppendLine(XmlHeader);

            if (yft?.Fragment != null)
            {


coronary artery disease, and to compare procedural strategies related to patient and physician influences to strategies suggested by clinical trials. The study will encompass two main approaches. The first approach will be to directly examine the patient decision process by administering the Shared Decision Program (SDP) to patients facing treatment decisions following cardiac catheterization. The SDP is a computer based interactive video device that provides patients with easily understood information about their disease and potential therapeutic options in a neutrally framed format. The program also provides viewers with individualized comparisons of survival according for angioplasty, bypass surgery, and medical therapy. If patients are given sufficient information about their disease process and treatment options, they have a greater potential to actively participate in decisions about procedures, possibly selecting those          2
                                            III.

       In order for a lawful permanent resident to be eligible for cancellation of removal,

he must have maintained that status for a minimum of five years, resided in the United

States for seven continuous years, and not been convicted of an aggravated felony. 8

U.S.C. § 1229b(a). Cun argues that the BIA did not apply the categorical approach set

forth in Taylor v. United States, 495 U.S. 575 (1990), to determine


CT/St. Bernard School) did not make any stops in the final 2:52.

For the Bears, Wall had two goals, while Milligan made nine saves in the loss in goal.

The Engineers return to the field next weekend, opening their Liberty League schedule at Rochester and RIT on Friday (4:00 pm) and Saturday (2:00 pm), respectively. The Bears are right back in action tomorrow with a game at Morrisville State (12:00 p.m.).running yet again. ("Here we go again. He doesn't give up easy, does he?") Wile E. Coyote then tries to be a "Coyote cannonball" to speed past Bugs, only to then point the cannon downward via his weight, and launch himself into the ground, forming a crater. After escaping the crater, Wile E. Coyote hits his ear to push rocks out of the other ear.

6. Finally, as Bugs times Wile E.'s arrival to him again, he remarks to the viewers: ("Yep. Here comes the old 5-15 now. Right on time.") Then Bugs runs off and he is able to place a large patch of glue in the road. Wile E., unable to stop in time, ends up stuck in the puddle and tries to reach a ringing phone


and Respondent,

         v.

JACOBUS A. ODYK,

              Defendant and Appellant.

APPEAL FROM:         District Court of the Fourth Judicial District,
                     In and for the County of Missoula, Cause No. DC 96-12270
                     The Honorable Edward P. McLean, Judge presiding.

COUNSEL OF RECORD:

              For Appellant:

        most of any single from (Miss)understood. It went on to sell 316,663 copies, receiving a platinum certification. The third single, "Heaven", experienced similar success: it reached number one, and was certified Platinum, selling around 325,000 copies. "Bold & Delicious/Pride" was not as successful. Despite reaching number one, it became her poorest-selling single at the time since 1998's "Depend on You", selling only 133,000 copies.

(Miss)understood was commercially successful, opening at number one in Japan (her eighth consecutive record to do so) with first-week sales of 653,830 copies. It went on to sell over 877,000 copies in Japan in its 31-week chart run, receiving a Million certification and becoming the 8th best-selling album of 2006. It is, to date, her last Million-certified album. According to Avex, It is also her


driving through areas of New York City, evoking the iconic 1993 Björk music video for her single "Big Time Sensuality". Some shots feature "behind the scenes" material, showing footage of the truck driving around the city and film crew members.

The video for "Pride" features several long takes of Hamasaki in a black dress being prepared by assistants and make-up artists, and then walking through an on-location set prepared under a New York City bridge and in the rain.

The music video for "Ladies Night" features Ayumi wearing a pink and blue mini dress, and her legendary long blue leg muffs as she walks down a hotel hallway, trying to go into some of the rooms, and occasionally singing into a payphone. Scenes of different things happening in the roomsyesterday in the journal Nature, helps reconcile a situation that has puzzled scientists.

Climate models project that Amazon deforestation would reduce rainfall regionally. But limited observations show that rainfall in deforested areas is higher than in areas where the rainforest is still intact.

(Scientists believe that when trees are cut down, the bare surfaces left behind absorb more Read more…

RAINFOREST TO PASTURE: Deforestation, among other human impacts such as climate change, are having a rainforest-wide impact on the Amazon. Image: Courtesy of Compton Tucker, NASA GSFC

The Amazon rainforest is in flux, thanks to agricultural expansion and climate change. In other words, humans have “become important agents of disturbance in the Amazon Basin,” as an international consortium of scientists wrote in a review of the state of the science on the


them with us!

Named after the common cookie, I wasn’t sure what to expect from Snickerdoodles Bakery and Coffeehouse (Hampstead, MD). Would it just be a take-out bakery that you stop in on your way to work for a quick cup of coffee and a muffin? When I finally went to their shop, I was surprised and pleased to find a sophisticated bakery and high-end coffeehouse, with plenty of room to bring friends and gather around one of their many tables, or just to come yourself and relax in their cozy surroundings. The mom in me loved seeing that they even have a miniature table with chairs, inviting guests to bring their kids with them.

After taking in the great atmosphere, I began investigating the goodies. My first thought? “WOW!York times by abusing such a security hole which is documented under http://www.securityfocus.com/news/340.

More than enough reasons to write a program that scans an IP frame for open proxy servers by trying to make a direct socket connection to well-known proxy ports like 3128 and 8080. If not told otherwise it will attempt to access Google in order to realize if the proxy is really open and working as expected. An automated detection is not as trivial as it seems, thus a webserver could also respond with HTTP code of 200 and a custom error page if it denies the access. Therefore the tool dumps the whole HTML code so the user can decide for himself if the request was successfully or not.

1 #!/usr/bin/python

2

3 import sys

4 import os

5 import


quite similar to those of the RFCOMM channel scanner, but it only connects to a single channel (17 by default) and sends the commands received by the user in an endless loop as long as you don't type "quit" or "exit". To read the user input we use the function raw_input(), which can receive a prompt as a parameter.

## 9.9 Bluetooth-Spoofing

For a long time Bluetooth spoofing seemed to be impossible due to the fact that the sender address, other than in Ethernet, is not set by the kernel of the operating system. It is set by the firmware of the Bluetooth chip. For two different chipsets (CSR and Ericcson) codes exist (or at least the author is not aware of any other) that allows you to set anyin abusing DHCP, cause it serves an easy way to configure himself as a DNS server and avoid the need of DNS spoofing (Sect. 6.7) or to declare himself as the default gateway to be able to read the complete internet traffic without applying ARP-Cache-Poisoning (Sect. 4.2). In the simplest case an attacker configures his own DHCP server that's sending responses to all requesting clients to achieve this aim, but this has a big disadvantage by revealing the attackers MAC address and make him traceable by trivial means. An intelligent attacker therefore would write their own tool to create a perfectly spoofed DHCP-ACK packet that looks like it's coming from the real DHCP server of the network.

1 #!/usr/bin/python

2

3 import sys

4 import getopt

5 import random

6 import scapy.all as scapy

7

8


know any good refrence for orm
thx for help

A:

I'm assuming the group by is for ordering.  If you really want group_by look at aggregates and annotate in django.  My guess of what you are looking for is:
1: Get the person record - select person_name from Person
 person = Person.objects.get(<WHERE clause>).values('person_name')

2: select *
   from Person,Car
   where car_owner=person_id
Get the cars belonging to the person
cars = Car.objects.filter(car_owner = person)

3: select *
   from Person,Car
   group_by(person_name)
Get list of cars sorted by owner
car_list = Car.objects.all().order_by('car_owner__person_name')

4: select *
   from Person,Car
   where name like %x%
   group_by(person_name)
   having car_id >= 2
List of cars with search criteria
car_list = Car.objects.filter(id__gte = 2, car_name__contains = "<search>").order_by('car_owner__person_name',)

Cars and their Owners
car_list = Car.objects.all().values('car_name','car_owner__person_name')

TEC has been … [Read more...]

Imagine trying to launch a business without a unique product or trying to start a restaurant without a unique style. Without a vision, the odds of being an effective and successful company are slim to none. That’s why THSC holds firm to our vision of a bright future for Texas families by championing … [Read more...]

https://www.facebook.com/TexasHomeSchoolCoalition/videos/1619762084748842/
Texas Senator Joan Huffman is currently running for re-election in Senate District 17. Before heading to the polls, homeschoolers need to be aware of Senator Huffman’s record opposing efforts to defend the rights of … [Read more...]


EPO was described by Miyake et al. (J. Biol. Chem. 252, 5558 (1977)). The identification, cloning, and expression of genes encoding erythropoietin is described in U.S. Pat. No. 4,703,008 to Lin. A description of a method for purification of recombinant EPO from cell medium is included in U.S. Pat. No. 4,667,016 to Lai et al.
Little is known about the mechanism by which EPO stimulates erythropoiesis. While it is clear that EPO activates cells to grow and/or differentiate by binding to specific cell surface receptors, the specific mechanism of activation as well as the structure of the receptor and any associated protein(s) is not completely understood. The erythropoietin receptor (EPO-R) is thought to exist as a multimeric complex. Sedimentation studies suggested its molecular weight is 330.+-.48 kDa (Mayeux etBlood 82, 197A (1993) used the same monoclonal antibodies as described in D'Andrea, supra to distinguish erythroid progenitor cells having EPO-dependent growth and maturation from those having EPO-independent growth and maturation.
None of the antibodies described in the aforementioned references were reported to activate the EPO receptor or stimulate the growth and/or maturation of erythroid progenitor cells.
Therefore, it is an object of the invention to produce antibodies which recognize an EPO receptor and bind to it such that the receptor is activated. It is a further object of the invention to produce antibodies which bind to an EPO receptor and stimulate erythropoiesis by stimulating the proliferation and/or differentiation of erythroid progenitor cells to erythrocytes. Such antibodies are useful in the treatment of anemia or in the diagnosis of diseases


velocity and distance may approximate to EQU V=k'h.sup.n
where k' is a constant and n is at least 1.5 better 2 or more. In particular it is preferred to approximate such a formula in which n=3. Then the compressive force will remain roughly constant as distance h decreases.
Such a relationship has the consequence that velocity and distance satisfy an inequality: ##EQU2## where m.gtoreq.1.5, e.g. m.gtoreq.2.
By arranging relative velocity to follow such a relationship to distance it is possible to achieve a reduction in the maximum compressive force while increasing the relative velocity of the dies at the moment of initial contact with the billet, and so not increasing the overall stamping cycle time.
The invention thus leads to a reduction in the occurrence of die blocks, yet the overall rate     {
                Url = audience,
                AccessToken = jwtBearer
            };
        }

        private string GenerateJwtBearer(string issuer, string audience, ClaimsIdentity subject, DateTime? expires, string signingKey)
        {
            SigningCredentials signingCredentials = (SigningCredentials)null;
            if (!string.IsNullOrEmpty(signingKey))


D-Ill., before the stirring "A More Perfect Union" speech on race relations during the presidential race that would propel Obama to the White House.

In 2016, Wofford described the merging of his personal and political ideals in an essay published in The New York Times, "Finding Love Again, This Time With a Man."

Wofford, by then a widower, described how he met Matthew Charlton, an interior designer 50 years his junior, and the two became a couple. The essay ended with Mr. Wofford's announcement that he and Charlton would soon exchange marriage vows. They wed that year.

The courtly, professorial nonagenarian said he did not consider himself gay. "Too often, our society seeks to label people by pinning them on the wall — straight, gay or in between," he wrote. "Iwhich compute the images generated by optical projection systems, have proven to be a valuable tool to analyze and improve the state-of-the-art in optical lithography for integrated circuit fabrication. These simulations have found application in advanced mask designs having many levels of hierarchy, such as phase shifting mask (PSM) design, optical proximity correction (OPC) for mask design, and the like. Modeling aerial images is a crucial component of semiconductor manufacturing. Since present lithography tools employ partially coherent illumination, such modeling is computationally intensive for all but elementary patterns. The aerial image produced by the mask, i.e., the light intensity in an optical projection system's image plane, is a critically important quantity in microlithography for governing how well a developed photoresist structure replicates a mask design.
However, optical proximity correction


I saw The Red Shoes (1948) aged nine or 10. My father took me. Seeing it that first time was an overwhelming experience for me. My father, who worked in the garment district in New York, certainly wasn't an educated man but he did like films. For some reason, he took me to see The Red Shoes. I certainly don't think he was a ballet enthusiast. I believe that the film had picked up an audience here in America. Everyone was talking about it and so he wanted to see it.

My father liked the film very much too. We always used to talk about it. He liked it for its sense of mystery in terms of the character of Lermontov (the driven ballet impresario played by Anton Walbrook)up to date about the appreciation of his and Emeric's work among the younger film-makers. My friends and colleagues were still trying to find good colour copies of the work or at least extant copies of A Canterbury Tale (1944). I do talk rather quickly. I was excited. He seemed rather modest and somewhat taken aback. Quite honestly, I guess I spoke so much, I don't remember what he told me.

Powell had gone from making "quota quickies" (low budget British films) in the 1930s on to his collaboration with Pressburger and then on to a film like Peeping Tom (1960). When I was at Washington Square College, which was part of New York University at the time, there was a very, very small film department. Peeping Tom became


1. Field
This disclosure relates to a medical use driver tool and, in particular, to a torque-limiting driver that disengages at a predefined torque limit.
2. General Background
Torque-limiting drivers are widely used throughout the medical industry. These torque-limiting drivers have a factory pre-set torque to ensure the accuracy and toughness required to meet a demanding surgical environment.
The medical industry has made use of both reusable and disposable torque-limiting drivers. In a surgical context, there is little room for error and these drivers must impart a precise amount of torque.
Reusable drivers require constant recalibration to ensure that the driver is imparting the precise amount of torque. Recalibration is a cumbersome task but must be done routinely.
Disposable drivers are an easy to use and reliable alternative to the reusable drivers. Typically, aActivities;

The Special Voluntary Trust Fund (BI Trust Fund) for Facilitating Participation of Developing Country Parties, in particular the Least Developed and the Small Island Developing States amongst them, and Parties with Economies in Transition.

Government of Korea pledge USD 60,000 towards the convening of a Workshop on financing for biodiversity to provide technical inputs to the Pyeongchang 2020 Roadmap, 18-19 August 2014, Zurich, Switzerland.

Norway pledge NOK 100,000 - Participation of indigenous and local communities in the third meeting of the Intergovernmental Committee of the Nagoya Protocol on Access and Benefit Sharing, Pyeongchang, Republic of Korea, 24-28 February 2014

Finland pledge EUR 30000 - Participation of delegates from developing countries and economies in transition in the meetings of the COP-12 and COP-MOP/1 of the Nagoya Protocol on Access and Benefit-sharing, Pyeongchang,


packed with calories – a good broth can do wonders.

There are good kinds of fat

There are good kinds of fat – in fact, your body needs these kinds of fat to help absorb nutrients from the food you eat. Unsaturated fats (both mono- and poly-) give you the right fats and vitamin A, D, and E. Try olive oil, almonds, avocadoes, and other ingredients, and avoid processed foods.

Slimming sweets

Refined sugars can be found all around during the winter months, but avoid them – they’re going to disrupt your plans. You’ll crave sweets and sugars, but stick to the sweetness in vegetables such as roast beets, sweet potatoes, and winter pumpkin.

Sleep well

Your body will automatically need more sleep. Indulge. Get plenty of sleep, as someone who’s enthusiastic about sportsQ:

GCC: How to generate line number debug information only?

I would like to improve the build speed of a large project. The opt build is compiled with -O2 -g. I noticed that without -g, compilation becomes faster, about 10-20%. The resulting binary has enough information to analyze crashes, except for the line numbers. Is there a way to include line number information but nothing else?
According to http://gcc.gnu.org/onlinedocs/gcc/Debugging-Options.html, line numbers are produced only at level 2 (i.e. -g2 or the default of -g) or above. But according to this http://gcc.gnu.org/wiki/DebugFission, line numbers are only a fraction of the debug information (1%). So for me it would be best to have -g0 or -g1 but with line numbers. Is this possible?
Best regards,
Martin

A:

Googling the Clang option mentioned by Matthieu, I found a


$\gamma_1,...,\gamma_k$ in $\Gamma_{{\langle}1,\cdots,n {\rangle}}$ and $\tau^{\varepsilon}_k$ is then the restriction of $\tau^{\varepsilon}_n$. We may sometimes simply write $\tau^{\varepsilon}$ without any reference to $n$. Finally, we remark that with the classical identification $x\mapsto x1$ between $\Gamma_{{\langle}1,\cdots,n
{\rangle}}$ and $H$, $\tau^{\varepsilon}$ corresponds to $\phi^{\varepsilon}$.

We collect some results about $\gamma_i$’s which we need in the sequel.

\[prop-gamma\]We have:

1.  For all $n\geq 1$, and $i\leq n$, $\sigma^{\tau^{\varepsilon}}_t(\gamma_i)=\mu^{4it} \gamma_i$ and $\tau^{\varepsilon}(\gamma_i^*\gamma_i)=\mu_i^{-2}$.

2.  Let $D_{{\langle}1,\cdots,n {\rangle}}$ and $D_{{\langle}1,\cdots,n-1 {\rangle}}$ be the densities of $\tau^{\varepsilon}$ restricted to $\Gamma_{{\langle}1,\cdots,n {\rangle}}$ and $\Gamma_{{\langle}1,\cdots,n-1 {\rangle}}$, respectively. Then we have a natural isometric embedding $$L^p(\Gamma_{{\langle}1,\cdots,n-1 {\rangle}}) \hookrightarrow L^p(\Gamma_{{\langle}1,\cdots,n {\rangle}}),
                    \;\; x D_{{\langle}1,\cdots,n-1 {\rangle}}^{\frac{1}{p}} \mapsto x D_{{\langle}1,\cdots,n {\rangle}}^{\frac{1}{p}}.$$ A similar statement holds  {\varepsilon}((i_1,i_2), (j_1,j_2)) = {\varepsilon}(({\left\verti_1\right\vert},{\left\verti_2\right\vert}), ({\left\vertj_1\right\vert},{\left\vertj_2\right\vert})),
    \; \forall (i_1,i_2), (j_1,j_2)\in \widetilde{I}. \end{array}$$ Now we replace ${\varepsilon}((i_1,i_2), (j_1,j_2))$, $(i_1,i_2) \prec (j_1,j_2)\in \widetilde{I}$ with a family of i.i.d. random variables with $$P({\varepsilon}((i_1,i_2), (j_1,j_2))= -1) = \frac{1-q}{2}, \;\; P({\varepsilon}((i_1,i_2), (j_1,j_2))= 1) = \frac{1+q}{2},$$ where $(i_1,i_2) \prec (j_1,j_2)$ means $i_1<j_1$ or $i_1=j_1, i_2<j_2$. We set $$s_{i,m} = \frac{1}{\sqrt{m}}\sum^m_{j=1}\gamma_{i,j}.$$ Then, the Speicher’s central limit procedure ([@Sp92; @N06]) tells us the following.

\[prop-n-var\] For any $*$-polynomial $Q$ in $n$ non-commuting variables we have $$\lim_{m\rightarrow \infty}\tau^{\varepsilon}(Q(s_{1,m}, \cdots, s_{n,m})) = \tau_q(Q(g_{q,1},\cdots, g_{q,n}))$$ for almost every ${\varepsilon}$.

Since the set of all non-commuting $*$-polynomials is countable, we can find a choice of sign ${\varepsilon}$ such that the above is true for any $Q$. In the sequel we fix such an ${\varepsilon}$.

Now we would like to


+ o({\varepsilon}^2).
    \end{aligned}$$

Consequently, ${\left\VertP^t_q(a({\varepsilon}))\right\Vert}_{2n} \le {\left\Verta({\varepsilon})\right\Vert}_2$ implies that $$1 + \frac{n}{2} e^{-2t}{\varepsilon}^2 \mu^{2-\frac{4}{n}}_i + o({\varepsilon}^2)
    \le 1 +  \frac{{\varepsilon}^2}{2}\mu^{-2}_i + o({\varepsilon}^2),$$ which means $$\label{1-dim-estimate}
    e^{-2t} \le \frac{1}{n}\mu^{-4+\frac{4}{n}}_i \le 2\mu^{-4+\frac{8}{2n}}_i\frac{1}{2n-1}$$ by taking ${\varepsilon}\rightarrow 0$. By duality we get the following.

\[thm-1-dim\] Let $\frac{1}{p} = 1 - \frac{1}{2n}$, $n(\ge 2) \in {\mathbb{N}}$. Then ${\left\VertP^t_q\right\Vert}_{L^p \rightarrow L^2} \le 1$ implies that $$e^{-2t} \le 2\alpha_\mu^{4-\frac{8}{p}}(p-1).$$

If we turn back to the baby Fock model, this one dimensional estimate can be extended for all $1<p<2$. That is, Theorem \[thm-eps\] is optimal.

Let $d\in \mathbb M_n$ be an invertible self-adjoint matrix, and $g\in \mathbb
M_n$, such that $dg=\lambda gd$ for some $\lambda>1$. Then, for any $p>2$, $$\| (1+{\varepsilon}g)d \|_p^p={\rm Tr}\, d^{p} + {\varepsilon}^2\left(\Big(\frac p
2 +c_{p,\lambda}\Big) \, {\rm\frac p 2 \, {\rm Tr}\, x^{p/2-1} h$$ $${\rm Tr}\,({\rm diff^2}_x  f. (h,h))=  2 \cdot {\rm Tr}\, \Big(\sum_{s,t} f_2(s,t,s) p_shp_th\Big).$$ We want the expansion at the second order in ${\varepsilon}$ of $$\|(1+{\varepsilon}g)d\|_p^p= {\rm Tr}\, (d^2 + {\varepsilon}d(g+g^*)d +{\varepsilon}^2 d
g^*gd)^{p/2}.$$ By the above formula, with $x=d^2$, the first order term is $\frac p 2 \, {\rm Tr}\, d^{p}(g+g^*)=0$ because of the commutation relation as $\lambda\neq 1$.

By the Taylor expansion, the second order term has two contributions, one from the first derivative, the other coming from one half the second one. The first is given by $\frac p 2 \, {\rm Tr}\, d^{p}g^*g$. The second is more involved; let $d=\sum_{\alpha\in \sigma(d)} \alpha p_{\alpha}$ be its spectral decomposition, we get $$\begin{aligned}
 A&=&{\rm Tr}\, \Big(\sum_{\alpha,\beta
\in \sigma (d)} f_2(\alpha^2,\beta^2,\alpha^2)
p_\alpha d(g+g^*)dp_\beta


Perseveration and rotational behavior elicited by d-amphetamine in a Y-maze exploratory task: differential effects of intraperitoneal and unilateral intraventricular administration.
Mice received either intraperitoneal (1.0, 3.0, 5.0, or 15.0 mg/kg) or unilateral intraventricular injection (50.0, 100.0 or 200.0 microgram) of d-amphetamine. Both routes of injection produced circling behavior in a dose-related fashion when animals were tested in a circular alley-way. In contrast, performance in a free running Y-maze alternation task was differentially affected by the route of administration. Whereas intraperitoneal injection induced perseveration (i.e., animals consecutively visited only two arms of the maze), intraventricular injection augmented alternation behavior normally seen in saline-treated mice. It was suggested that Y-maze performance following intraventricular d-amphetamine injection reflects response perseveration, whereas systemic d-amphetamine treatment produced stimulus perseveration (repetition of location rather than direction).   1 month
  Cough Suppressant (Morphine, Disofrol)                                  2 months
  GABA agonist (Baclofen) TDS                                             2 months

Method
======

Patients
--------

30 adult patients with CF diagnosed on the basis of clinical presentations and confirmed by sweat tests or genetic investigation, are under the care of the Hull adult CF unit. 18 patients were


anaesthesia with full muscle relaxation using a five port technique. In every case the oesophageal hiatus was fully dissected and the oesophagus mobilised. At least one non absorbable suture was placed to approximate the crura posterior to the oesophagus and to minimise the risk of post-operative herniation. In cases where there was a large pre-existing hiatal defect, additional posterior crural sutures were placed as required. In most cases there was no obvious hiatus hernia demonstrated at surgery. Calibration of the oesophageal hiatus was clinical but in cases of doubt a 56 Fr endoluminal bougie was available to calibrate the appropriate size.

Outcomes
--------

Our primary outcome measure was the change in cough as assessed by self-administered Leicester Cough Questionnaire (LCQ). Pre- and post-operative changes in spirometry and exacerbation rate as definedby an event requiring antibiotics (oral or IV), were secondary endpoints. Results are expressed as means and standard deviations (SD), and the comparisons pre and post- operatively were made by paired t-test with 95% confidence interval (CI), using SPSS software version 13.

Results
=======

Demeester score, esophageal ph and manometry studies pre-operation
------------------------------------------------------------------

Of 18 patients with clinically diagnosed reflux cough, four men and two women with a mean age of 34.5 ± 14.7 years, failed to show any improvement with the standard medical therapy of reflux cough. In the 5 patients consenting to oesophageal studies, the mean number of reflux episodes was 144.4 (range from 97 to 178), and pre-operative mean DeMeester score was 39.2 (± 24). The mean resting pressure of lower oesophageal sphincter was 12.4. Reported cough was highly associated


scores from each of its three domains. Total LCQ score improved significantly from 11.9 (± 3.2) to 18.3 (± 1.2), *P*= 0.01 (CI: 2.2 to 10.4).

In the physical domain mean score increased from 3.2 (± 0.95) to 6(± 0.4), *P*= 0.002 (CI: 1.5 to 3.9). Mean scores from social domain increased from 4 (± 1.4) to 6.5 (± 0.6), *P*= 0.01 (CI: 0.8 to 4.2). In the psychological domain, scores increased from 4.5 (± 0.9) to 5.7(± 0.5), *P*= 0.06 (CI of -0.1 to 2.4). (Figure [1](#F1){ref-type="fig"})

![**LCQ domains before and after fundoplication**.](1745-9974-5-1-1){#F1}

Spirometry
----------

Forced expiratory volume in one second (FEV1) increased from a mean of 1.03L (± 0.32) to 1.17L (± 0.41), *P*= 0.04 (95%CI = 0 to 0.25), and forced vital capacity (FVC) improved from a mean of 2.62Lmany patients may progress to transplant assessment.

Technically, fundoplication is subtly more difficult in CF patients than in normal subjects with reflux. The tissues are generally more friable and edematous perhaps as a result of previous use of systemic steroids or as part of the systemic disease. In our patients, there were no operative or post-operative complications. Weight loss and dysphagia, recognised operative complications were trivial and short lived.

Our experience in the diagnosis and treatment of chronic cough, led us to the realisation that many patients with CF complain of a similar symptom profile indicative of reflux. In common with other reports, these patients have excessive acid reflux which we found to be unresponsive, in terms of cough, to medical anti-reflux therapy. Fundoplication produced a dramatic symptomatic improvement associated


Young Rembrandts

Art Classes Just for Children

Young Rembrandts was created to be fun. Young Rembrandts drawing classes offer child-friendly and relevant subject matter to spark interest and increase knowledge retention, never losing sight that children learn best when they are engaged and entertained.

Our drawing programs are based on an acclaimed, step-by-step drawing method that works hand-in-hand with original art curriculum developed by a team of educators and artists. Our multi-sensory approach to learning meets every child at their level.

Weekly sessions are designed so a child can be enrolled from preschool to sixth grade and never repeat a lesson. This allows students to continually build skills and develop their personal style and creativity.

For information about up coming after school classes held at SJA or to register for the next classSee id. at (e)(1) (borrowing state law method for "action brought in courts of general jurisdiction in the state where the district court is located"); Holmes v. Gonzalez, No. 1:09-CV-259, 2010 WL 1408436, at *3-4 (E.D.Tenn. Apr. 2, 2010) (slip copy) (noting Rule 4(e)(1) state-law method for effectuating service to be alternative to Rule 4(e)(2) authorized methods). Kentucky law likewise permits personal service. See Ky. R. Civ. P. 4.04(2). The question becomes whether that service fixed personal jurisdiction under constitutional principles.[2]
Burnham clearly endorses the validity of jurisdiction via personal service. Though no majority opinion exists, nine Justices agreed in the case that personal service on a non-resident effected jurisdiction in California as to a cause of action unrelated to the non-resident's activities within the forum state.[3] Justice Scalia's


Justice Brennan concurred in the judgment without further fairness or burden inquiry. See id. at 2126. Like the petitioner in Burnham, Pavlovsky was served while voluntarily in the forum, here in Kentucky to attend a horse sale in this District. Under either central theory announced in Burnham, jurisdiction would satisfy due process.
The defense rationally tries to distinguish Pavlovsky's situation because he is a foreign citizen. Based on statements in Asahi Metal Industry Co., Ltd. v. Superior Court of California, Solano County, 480 U.S. 102, 107 S.Ct. 1026, 94 L.Ed.2d 92 (1987),[5] Defendant argues that foreign defendants receive additional protection (relative to burden, inconvenience) in the due process calculus. The Court questions the application of Asahi in the context of personal (versus long-arm) service.[6] The Scalia analysis ignores burdenconduct is at issue, and a defendant that creates "`continuing obligations' between himself and the residents of the forum" has availed himself of the privilege of forum involvement. See Air Products, 503 F.3d at 551. A singular contract alone may not suffice, but an on-going relationship, indicating repeated intentional activities directed toward the forum, meets this criterion. Defendant formed his relationship with a known Kentucky entity. The twelve-year relationship grew from contact in Kentucky, and the very business centered on trade in horses purchased at public and private sales in the Commonwealth. SEI's Kentucky presence was a key to the operation, offering local credit for purchases and then a site to board horses in transition. SEI, from Kentucky, procured insurance and other services for horses owned or held


                @foreach (var provider in Model.OtherLogins)
                {
                    <button type="submit" class="btn btn-default" name="provider" value="@provider.Name" title="Log in using your @provider.DisplayName account">@provider.DisplayName</button>
                }

    </form>
}
Hillary Clinton won the Democratic Woman of the Year Award Thursday. As the New York Times reports, Clinton brought her admiring audience at the Women’s National Democratic Club to tears.

Award presenter Nuchhi Currier could barely contain her emotion when she remembered the last presidential election produced a result that was “very different from what had been anticipated.”

Especially after Clinton secured the nomination through a rigged process, former Democratic National Committee chairwoman Donna Brazile alleged in a Politico interview. That assessment was quietly but firmly endorsed by left-leaning Democratic Sen. Elizabeth Warren.

The negative talk apparently didn’t faze Clinton. She told the crowd, “I got more votes than anybody except Barack Obama in 2008,” as she again insisted her popular vote overshadowed Trump’s victory in the Electoral College.

Clinton, who has


convert the quaternion to a rotation vector and find its length
        deltaQuatTemp.to_axis_angle(deltaRotVecTemp);

        // check if the spin rate is OK - high spin rates can cause angular alignment errors
        bool angRateOK = deltaRotVecTemp.length() < 0.1745f;

        initialResetAllowed = angRateOK;
        flightResetAllowed = angRateOK && !onGround;

    }

    // reset the limit on the number of magnetic anomaly resets for each takeoff
    if (onGround) {
        magYawAnomallyCount = 0;
    }

    // Check if conditions for a           // A 321 rotation order is best conditioned because the X axis is closer to horizontal than the Y axis
                if (!onGroundNotMoving) {
                    yawAngDataDelayed.yawAng = atan2f(prevTnb[0][1], prevTnb[0][0]);
                }
                yawAngDataDelayed.type = 2;
            } else {


               // fuse last known good yaw angle before we stopped moving to allow yaw bias learning when on ground before flight
                fuseEulerYaw(false, true);
            } else {
                // prevent uncontrolled yaw variance growth by fusing a zero innovation
                fuseEulerYaw(true, true);
            }
        magTimeout = false;
        lastHealthyMagTime_ms = imuSampleTime_ms;
    } else if ((imuSampleTime_ms - lastHealthyMagTime_ms) > frontend->magFailTimeLimit_ms && use_compass()) {
        magTimeout = true;
    }

    if (effectiveMagCal != MagCal::EXTERNAL_YAW_FALLBACK) {
        // check for and read new magnetometer measurements. We don't
        // real for EXTERNAL_YAW_FALLBACK as it has already been read
        // above
        readMagData();
    }

    // check for availability of magnetometer or other yaw data to fuse
    magDataToFuse = storedMag.recall(magDataDelayed,imuDataDelayed.time_ms);


      if (PV_AidingMode != AID_ABSOLUTE ||
                (frontend->_mag_ef_limit > 0 && have_table_earth_field)) {
                FuseDeclination(0.34f);
            }
            // fuse the three magnetometer componenents using sequential fusion for each axis
            hal.util->perf_begin(_perf_test[0]);
            FuseMagnetometer();
            hal.util->perf_end(_perf_test[0]);
         q0*q0 - q1*q1 - q2*q2 + q3*q3;
    MagPred[0] = DCM[0][0]*magN + DCM[0][1]*magE  + DCM[0][2]*magD + magXbias;
    MagPred[1] = DCM[1][0]*magN + DCM[1][1]*magE  + DCM[1][2]*magD + magYbias;
    MagPred[2] = DCM[2][0]*magN + DCM[2][1]*magE  + DCM[2][2]*magD + magZbias;

    // calculate the measurement innovation for each axis
    for (uint8_t i = 0; i<=2; i++) {
        innovMag[i] = MagPred[i] - magDataDelayed.mag[i];
    }

    // scale magnetometer observation error with total angular rate to allow for timing errors
    R_MAG = sq(constrain_float(frontend->_magNoise, 0.01f, 0.5f)) + sq(frontend->magVarRateScale*imuDataDelayed.delAng.length() / imuDataDelayed.delAngDT);

    // calculate common expressions used to calculate observation jacobians an innovation variance


 if (obsIndex == 0) {

            for (uint8_t i = 0; i<=stateIndexLim; i++) H_MAG[i] = 0.0f;
            H_MAG[0] = SH_MAG[7] + SH_MAG[8] - 2.0f*magD*q2;
            H_MAG[1] = SH_MAG[0];
            H_MAG[2] = -SH_MAG[1];
            H_MAG[3] = SH_MAG[2];
            H_MAG[16] = SH_MAG[5] - SH_MAG[4] - SH_MAG[3] + SH_MAG[6];
            H_MAG[17] = 2.0f*q0*q3 + 2.0f*q1*q2;
           H_MAG[18] = 2.0f*q1*q3 - 2.0f*q0*q2;
            H_MAG[19] = 1.0f;
            H_MAG[20] = 0.0f;
            H_MAG[21] = 0.0f;

            // calculate Kalman gain
            SK_MX[0] = 1.0f / varInnovMag[0];
            SK_MX[1] = SH_MAG[3] + SH_MAG[4] - SH_MAG[5] - SH_MAG[6];
            SK_MX[2] = SH_MAG[7] + SH_MAG[8] - 2.0f*magD*q2;


+ P[14][2]*SH_MAG[0] - P[14][3]*SK_MY[2] - P[14][17]*SK_MY[1] - P[14][16]*SK_MY[3] + P[14][18]*SK_MY[4]);
                Kfusion[15] = SK_MY[0]*(P[15][20] + P[15][0]*SH_MAG[2] + P[15][1]*SH_MAG[1] + P[15][2]*SH_MAG[0] - P[15][3]*SK_MY[2] - P[15][17]*SK_MY[1] - P[15][16]*SK_MY[3] + P[15][18]*SK_MY[4]);
            } else {
                // zero indexes 13 to 15 = 3*4 bytes
                memset(&Kfusion[13], 0, 12);
            }

            // zero Kalman gains to inhibit magneticindexes 22 to 23 = 2*4 bytes
                memset(&Kfusion[22], 0, 8);
            }

            // set flags to indicate to other processes that fusion has been performed and is required on the next frame
            // this can be used by other fusion processes to avoid fusing on the same frame as this expensive step
            magFusePerformed = true;
        }


     }
        for (unsigned j = 0; j<=stateIndexLim; j++) {
            for (unsigned i = 0; i<=stateIndexLim; i++) {
                ftype res = 0;
                res += KH[i][0] * P[0][j];
                res += KH[i][1] * P[1][j];
                res += KH[i][2] * P[2][j];
           faultStatus.bad_xmag = true;
            } else if (obsIndex == 1) {
                faultStatus.bad_ymag = true;
            } else if (obsIndex == 2) {
                faultStatus.bad_zmag = true;
            }
            CovarianceInit();
            return;
        }
    }
}

/*
 * Fuse magnetic


       gps_yaw_fallback_good_counter = 0;
    } else if (gps_yaw_fallback_good_counter < fallback_count_threshold) {
        gps_yaw_fallback_good_counter++;
    }
    bool ok = gps_yaw_fallback_good_counter >= fallback_count_threshold;
    if (ok) {
        // mark mag healthy to prevent a magTimeout when we start using it
        lastHealthyMagTime_ms = imuSampleTime_ms;
    }
    return ok;
}

// Reset states using yaw from EKF-GSF and velocity and position from GPS
bool NavEKF3_core::EKFGSF_resetMainFilterYaw()
{
    // Don't do a reset unless permitted by the EK3_GSF_USE and EK3_GSF_RUN parameter masks
    if ((yawEstimator == nullptr)
       || !(frontend->_gsfUseMask & (1U<<core_index))
        || EKFGSF_yaw_reset_count >= frontend->_gsfResetMaxCount) {
        return false;
    };

    float yawEKFGSF, yawVarianceEKFGSF;
    if (yawEstimator->getYawData(yawEKFGSF, yawVarianceEKFGSF) && is_positive(yawVarianceEKFGSF) && yawVarianceEKFGSF < sq(radians(GSF_YAW_ACCURACY_THRESHOLD_DEG))) {

        // keep roll and pitch and reset yaw
        resetQuatStateYawOnly(yawEKFGSF, yawVarianceEKFGSF);

        // record the emergency reset event
        EKFGSF_yaw_reset_request_ms = 0;
        EKFGSF_yaw_reset_ms = imuSampleTime_ms;
        EKFGSF_yaw_reset_count++;

        if (!use_compass() || AP::compass().get_num_enabled() == 0)


and turn on the see-saw mechanism [@seesaw], an appealing and natural scenery for neutrino mass generation.

The left handed neutrinos, members of the SM lepton doublet $\psi_{lL}^T=(\nu_l,l^-)_L, \; l=e,\mu,\tau $, can also acquire a Majorana mass $m_\nu$ which carries weak isospin I=1 and violates lepton number L by two units, generated either via non renormalizable operators obtained by using twice the SM Higgs doublet $\phi$, or due to coupling with a Higgs triplet $\Delta$ which develops non zero Vacuum Expectation Values (VEV), breaking in this way the lepton number spontaneously which in turn implies the existence of a Majoron [@gelron].

The alternative Zee mechanism [@zee1] can be implemented, when the L=2 Lorentz scalar $\psi_{lL}C\psi_{l^\prime L}$ (with $C$ the charge conjugation matrix) is coupled to an $SU(2)_L$ charged singlet $h^+$ with L$=-2$, introducing next3-3-1 for short), which provides a special framework for Majorana neutrino masses. The original model, which avoids the presence of exotic electric charges but includes heavy electrons [@ozer], is enlarged with a convenient set of Higgs fields in order to circumvent hierarchies in the Yukawa coupling constants. Besides, the presence of a large scale $V$ related to the breaking of $SU(3)_L\otimes U(1)_X$, triggers a see-saw mechanism for the charged leptons, that provides a realistic mass spectrum for the particles. At the same time, this mechanisms gives relationships that allow one to connect the mass eingenstates with the weak interaction states.

The analysis is done in a similar way that the one presented in Ref. [@canal], where a related calculation was carried through for the quarks in the 3-3-1 model with right


electric charge $2/3$ (the numbers inside the parenthesis stand for the $[SU(3)_c,SU(3)_L,U(1)_X]$ irreducible representations in that order); $Q^3_{L}=(u^3,d^3,D)_L\sim (3,3,0)$, where $D_L$ is an extra quark of electric charge $-1/3$. The right handed quarks are $u^{ac}_{L}\sim (3^*,1,-2/3),\; d^{ac}_{L}\sim (3^*,1,1/3)$ with $a=1,2,3,$ a family index, $D^{c}_{L}\sim (3^*,1,1/3)$, and $U^{ic}_L\sim (3^*,1,-2/3)$ for $i=1,2$.

The lepton content of the model, which contribute to the cancellation of the anomalies, is given by the following three $SU(3)_L$ triplets: $L_{lL} = (\nu_l^0,l^-.E_l^-)_L\sim (1,3,-2/3)$, for $l=e,\mu,\tau$, and the six singlets $l^+_{L}, E_{lL}^+\sim(1,1,1)$. Notice the presense of three exotic charged leptons $E_l^-$ (one per family), the fact that the model does not include right-handed neutrinos, and that universality is present at the tree-level in the weak basis.

With the former quantum numbers it is just a matter of countingexperimental results in Eq.(\[expn\]) up to $3\sigma$ deviations and for the inverted hierarchy of the neutrino spectrum [@moha], with the following predictions for the neutrino masses: $m_{\nu_1}= 0.0491\pm 0.0001$ eV, $m_{\nu_2}= 0.0483\pm 0.0001$ eV, and $m_{\nu_3}= 0.0016278\pm 3\times 10^{-7}$ eV, where the errors are statistical ones.

But $U_{PMNS}$ is not unitary in he context of this model (in general any model with physics beyond the SM produces a neutrino mixing matrix which is not unitary [@zhi]). In order to take into account this fact let us parameterize, in first approximation, such violation with three new parameters $\epsilon_i,\; i=1,2,3$ such that $$(U_{PMNS}U_{PMNS}^\dagger)_{ij}\approx \delta_{ij}(1+\epsilon_i)$$

These new parameters $\epsilon_i$ can be evaluated in first order in perturbation theory, keeping terms up to $\delta^2$, by the use of $M_e^{\prime\prime}$ in Eq. (\[mppe\]) which implies a diagonalization matrix


is a natural consequence of a two loop versus one loop quantum origen. All the above with a good dosage of fine tuning in some of the free parameters of the model.

Notice that the two-loop quantum corrections involved in this analysis, and the origen of the neutrino masses and mixing, are different from the Zee-Babu [@zee2; @babu] type mechanism, with all the free parameters of the model well constrained by the current neutrino oscillation data, with bounds that do not violate FCNC constraints, neither neutrinoless double beta decay limits.

The analysis presented here not only accommodates the neutrino mixing and oscillations, but it also throws neat prediction for the neutrino mass spectrum. Besides, the lower bounds on the masses of the exotic Higgs scalars of the model, could be probedLett. **81**, 1562 (1998); Q.R.Ahmad *et al* (SNO Collaboration), Phys. Rev. Lett. **89**, 011301 (2002); K.Eguchi *et al* (KamLAND Collaboration), Phys. Rev. Lett. **90**, 021802 (2003); Y.Ashie *et al*, Phys. Rev. Lett. **93**, 101801 (2004).

For recent reviews see: R.N.Mohapatra and A.Y.Smirnov, “*The neutrino mass and new physics*", \[hep-ph/0603118\], to appear in the Annual Review of Nuclear and Particle Science, Vol. **56**; G.Altarelli, Nucl. Phys. B, Proc. Suppl. **143**, 470 (2005).

P.Minkowski, Phys. Lett. B **67**, 421 (1977); M.Gell-Mann, P.Ramond, and R. Slansky, [*Supergravity*]{} (P.van Nieuwenhuizen at al eds.), North Holland, Amsterdam, 1980, p.315; T.Yanahida, in [*Proceedings of the Workshop on the Unified theory and the Baryon number in the Universe*]{} (O.Sawada and A.Sugamoto, eds.), KEK, Tsukuba, Japan (1979), p.95.

G.Gelmini and M.Roncadelli, Phys.Lett. B **99**,411(1981).

A.Zee, Phys. Lett. B **93**, 389 (1980); *ibid*, B **161**, 141 (1985);


Navigator will give us another tool to help them make the best possible energy management choices. If you know of anyone who could benefit from Energy Navigator or would like to learn more, please do let us know.= 'No support :(';
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clinical development. The majority of NNMs in clinical development incorporate already approved drugs and are based on a variety of drug delivery platforms, including polymeric micelles, liposomes, dendrimers, and inorganic nanoparticles (Torchilin, [@B105]; Wagner et al., [@B107]; Sercombe et al., [@B90]). Despite the arsenal of nanoparticulate targeted systems currently under preclinical development or in clinical trials, it is indisputable that liposomes are dominant on the NNM market (Table [1](#T1){ref-type="table"}) and were the first FDA-approved NNM (Caster et al., [@B11]; Shi et al., [@B93]). In fact, liposomes have all the necessary features to allow formulation of highly toxic and/or poorly soluble drugs, such as paclitaxel and amphotericin B (Min et al., [@B63]; Caster et al., [@B11]). Soon after their discovery in 1965 (Sessa and Weissmann, [@B91]; Deamer, [@B16]), liposomesshould refer to the development of realistic therapeutic platforms, in which therapeutic effects are maximized, doses are minimized, and complexity in dosage form design is reduced (Barz et al., [@B4]).

Complexity in dosage form design is a key factor in the ability for a NNM formulation to be translated to the clinic, irrelevant of its therapeutic efficacy. Simplification in formulation design is required to allow efficient and reproducible large-scale manufacturing (Grainger, [@B25]; Lammers, [@B47]; Barz et al., [@B4]). Any added complexities to the basic NNM platform would need to show significantly improved benefits that is reliable and reproducible in animal models and patients, due to the added costs and complexity in the manufacturing process. For example, further studies are required to examine the benefits of ligand-targeted delivery systems over