would work to his benefit if the Flying Spiders could generate some more runs).

On the offensive side of things, once heralded prospects Roger Kieschnick and Nick Noonan continue their struggles at the plate in their second go-around in the Eastern League. They flashed some promise in San Jose a couple of years ago, but they had dismal years in 2010 and things haven't changed much to start off the year in 2011. Kieschnick is currently batting .194 with a .513 OPS and isn't showcasing any of the power he showed when he broke in as a professional in the California League (23 home runs, .532 slugging in San Jose). He is walking more (0.53 BB/K ratio), but it hasn't made up for his 171 point drop in ISOis not really developing as a pitcher, but just going through a lucky patch. It'll be interesting to see how Marte will maintain his numbers as he garners more starts.

Augusta Green Jackets (8-18 after May 4th)

The Green Jackets have had serious problems with their pitching, and their 6.3 R/G allowed proves it. Youngsters Edwin Escobar and Edward Concepcion have really struggled in the SALLY, battling issues with their control and command. Escobar has appeared in four games, and has started two, but he has only pitched six innings total. He has given up 15 hits and 15 runs, and his ERA currently sits at 18.00 and his WHIP is 3.33. Furthermore, his K/BB ratio is one, so Escobar is getting guys on the basepaths (7.5 BB/9) and that


take a little getting used to, but it really does work quite effectively."

Conversant v Huawei & ZTE case. As Last week HHJ Hacon, sitting in the High Court, concluded a remote two-day Pre-Trial Review in the ongoingcase. As reported by the AmeriKat , the FRAND trial was due to take place at the end of April. At the Pre-Trial Review the defendants applied to vacate the upcoming trial. Despite creative proposals from an eager claimant to adapt trial timetables, produce longer written arguments and flexible scheduling, a 3-week trial with multiple expert and fact witnesses (who would normally be cross-examined in person) in circumstances where barristers and solicitors are juggling new realities on the home front was just not realistic.

paragraph 12 of the Protocol). Merpel encourages you towill not be disturbed. This is basic conference call hygiene.

2. Dress for the camera. For counsel appearing on video, remember to wear solid suits/ties/shirts - patterns (particularly stripes) disrupt, distort and can delay images.

3. All participants, save those who are speaking must be on mute.

4. Establish your own separate secure instruction channels to ensure efficient and quick communication between solicitors, barristers and clients via chat platforms and/or a separate dial-in for your legal team should barristers need to seek instructions. The court provides a private consultation facility, but as the court recognises:

"Legally privileged conversations with clients are fundamental to representative justice, and are a necessary part of our justice system. Our bespoke product for fully video hearings, which is subject to testing at the moment, provides for this


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 in the coming four years? What about my patients who are poor, dependent on government services to eat and survive? To those who are barely making it, vulnerable, sick? How will their lives change?

I worry about Mr. Bundy. He has emphysema and high blood pressure. Without the protections of the Affordable Care Act and the health exchange, he will be uninsured. How will he afford his expensive inhalers?

Of course, I won’t argue with Mr. Bundy today. I won’t ask him how he can support a man who preaches hate and intolerance. I won’t ask him if he thinks it’s appropriate to call the former Secretary of State a “nasty woman” on live television. I won’t tell him how hurt I am that a man who blatantly objectifies and


Q:

How can I deactivate Find my iPhone's Erase iPhone?

My iPhone 4s has been stolen and I have activated "Erase iPhone" through the iCloud, but I've found out that this disables Find My iPhone too.
How can I disable "Erase iPhone" to avoid deactivation of Find My Iphone?

A:

Apple doesn't provide a way for you to withdraw an erase command from iCloud. Theoretically, if it hasn't been withdrawn, an engineer for Apple could go in and remove it from the queue assuming:

They could verify you were really you
You figured out how to convince them to do this

As for whether you can still track the device after an erase is sent, that depends on the version of iOS on the device.
If you have iOS 7 or later - the erase actionwidth: 100%;
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having any expectations (hard to do for a Type A personality!). Thank God for Vicodan and a whirlpool tub in our room.

It's been three years since we've gone to a popular vacation spot and we were so shocked at how many rude, screaming, out-of-control children there were and how many people were constantly on their phones...texting, twittering, talking, etc. We didn't carry our phones with us most of the time...we wanted to get away and knew that Shanna had a good support system here if anything happened. While we were there, Epcot was hosting the Wine and Food Festival (which means there were a lot of people drinking and combine that with the heat and you have loud, rude people!). The parks were crowded and everything seemed toshe will be far away and we would likely not see a lot of her for several years, we also know that God is in control of her life and that this could very possibly be the best choice that she has ever made.

August 02, 2010

Russell, my brother Curtis and I spent Saturday at the Oregon Steam-up. This event is one that Russell and my brothers have attended for several years and I decided to tag along for the sole purpose of taking photos. I knew there would be a lot of “steam engines” but didn’t have any other expectations. Almost everything was outdoors and since the day started cool, I forego my Capri’s and sandals in favor of jeans and tennis shoes, andwas glad I did since


right outside our deck door…an owl, the occasional howl or bark of coyotes, frogs and in the distance, trains and planes.

As I sat in our living room listening to the night noises, I was so thankful to be living my life and am really trying to focus on the positive…to be thankful for who I am and what I have in my life…to live more in the moment. I’m thankful my daughter is home safe from her road trip. I’m thankful that I have a husband who wants to spend time with me and that we share such a wonderful life together. I’m thankful for family, and who loves me for who I am. One of my dear friends is going in for a biopsy tomorrow and I’mMom's character traits and talents. More than anything, my heart hurts that Shanna didn't get to know her Grandma Florine. My Mom would have loved Shanna's uniqueness, her sense of style and humor, her absolute belief in right and wrong, her innate kindness and most of all, the way that she loves and serves the Lord. I miss my Mom's hearty (loud) laugh that came from her soul (Shanna tells me I laugh too loud...something I used to tell my Mom when I was a teen...someday, hopefully she'll appreciate my laugh). My Mom struggled with her weight nearly her entire adult life, as do I. My Mom loved the Lord so much and was such a creative, giving, loving person...that's one of the best things about being a


Christian is knowing that I'll see her again someday...I imagine her in a beautiful heavenly garden and I'm thankful to have my very own "gardening" guardian angel. I love you and miss you Mom.

I think there are women who are born to be Mom's...they have that something extra and just seem to revel in all that motherhood entails. I'm not one of them...I love my girl with all my heart and soul but being a parent is hard work. I love this photo of my Mom and I...

My friend Amy (she and I have shared the journey of having Hep C and going through the year of treatment) is getting ready to have her first baby in just a few weeks. Amy, you're in my prayers and I                       I. BACKGROUND

      Laurent, a resident of Florida, filed this action pro se in the United States

District Court for the Southern District of Florida seeking relief based on events

that occurred during the pendency of a Chapter 13 bankruptcy action commenced

by Laurent in the Southern District of Florida. Laurent’s amended complaint

named as defendants Nancy N. Herkert, United States Bankruptcy Trustee; Joanne

M. Chin, the vice-president for BankAtlantic Federal Savings Bank #810;

BankAtlantic Federal Savings Bank; Hugo A. Martinez, a mortgagor who

foreclosed on Laurent’s home; Stephen N. Rosenthal, Martinez’s attorney; Elsa C.

Machado, a property tax collector; Rachel Baum, a county finance director; the


                        5
matter jurisdiction over Herkert, as Chapter 13 Trustee, because Laurent failed to

get permission from the bankruptcy court to sue her. See Carter v. Rodgers, 220

F.3d 1249, 1252 (11 th Cir. 2000) (concluding that a federal district court has no

subject matter jurisdiction over a suit against a Chapter 13 Bankruptcy Trustee

unless the plaintiff first obtains permission to proceed from the bankruptcy court).

Though Laurent argues that he did receive permission to file suit, he made no such

allegation in his amended complaint and did not seek leave from the district court

to amend that complaint to add such an allegation.

       Laurent additionallya belief about human nature,
that we can decide whether we agree with.
I mean, you should be aware that about
100 million people in the world right now
work for companies that are owned
by the workers together,
not by a separate owner.
I'm just saying.
Final thing then: competition.
Because in a capitalist economy,
all companies are
constantly trying to grow
and they're trying
to get bigger and bigger
and get more and more market share
and more and more money,
and there's no point at which
a capitalist economy has grown enough.
And that is why we see
capitalist companies
behaving towards each other
in a very aggressive way,
trying to kill each other off.
And that is why almost
everywhere you go in this country,
all the high streets
look exactly the same.
So, celebrating competition,
that's also based on an assumption
about human nature.

iw:
שוב, אמונה מסוימת בטבע האדם
שאפשר להחליט אם אנו


of them notorious ones,
like authoritarian socialism, for example,
they're not very nice either.
So I'm not saying everything
that is not capitalism
is automatically wonderful and great.
But there are other alternatives.
A much better alternative
is the cooperative movement,
and especially the nonprofit
cooperative movement,
because co-ops can organize without this
division between the owner and the workers
because they're the same people.
In a workers co-op, it's the workers
who own the company together.
Or in a consumer co-op,
it's the consumers;
or in a cooperative bank, it's the people
who hold accounts in the bank;
or in a housing co-op,
it's the residents who live there
who own the company together
and make decisions.
In the world right now,

iw:
או נותנים לחברים ממתקים
מבלי לדרוש תמורה כספית,
או כשאנו מתנדבים בפעילויות צדקה.
וחלק מהחלופות לקפיטליזם,
כמה חלופות ידועות לשמצה,
כמו סוציאליזם רודני, למשל,
גם הן אינן נחמדות במיוחד.
אינני טוענת שכל מה
שאיננו קפיטליזם
הוא אוטומטית נפלאthe fact
that some people,
and not a small number of people,
are already willing to invest their money
into a company that is never
going to make them rich.
So, instead of having beliefs
about making more money for themselves,
these people, they're interested
in something else.

Portuguese:
Era uma cafeteria,
e o objetivo do nosso negócio era
simplesmente prover boa comida e bebida,
em um bom ambiente,
por um preço tão baixo quanto possível.
E se ganhássemos dinheiro a mais,
apenas reduzíamos os preços.
Aliás, essa cafeteria
ainda funciona e prospera.
E no Reino Unido há algumas dezenas
de milhares de empresas
que não têm fins lucrativos.
Não estou falando de caridades,
mas de negócios que não visam lucro.
É difícil encontrar
um número mais específico
porque é difícil saber exatamente
o que é um negócio e o que é lucro,
mas algumas dezenas de milhares,
o que não é um número
estonteantemente enorme,
mas ilustra o


have difficulties -
like if there's a break-in
or a fire or something.
Big things and small things.
And there are already
several organizations in the UK
that do this today.
The biggest one is called
Co-operatives UK,
and there's a nonprofit
network, Radical Routes,
and several others as well.
I've been out to interview
some of the people in those
organizations for my research
and what they tell me
is they're not interested
in being on top of other people,
looking down on other people,
but they have a drive to do something
together with others.
So, what I'm saying
is that we should think of economy,
and capitalist economy,
not as a system or a machine,
but as community.

Portuguese:
Há muitas outras comunidades por aí
e aqui,
para além do capitalismo.
Enquanto cidadãos,
cidadãos que têm margem de manobra
para pensar nestas coisas,
temos de escolher
de que comunidades económicas
queremos fazer parte,
em que comunidades económicas
queremos trabalhar,
gastar o nossotoday's educational needs. Visit the United Negro College Fund on the web at www.UNCF.org

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What is the City of Houston's Office of Business Opportunity
The Office of Business Opportunity is committed to creating a competitive and diverse business environment in the City of Houston by promoting the growth and success of local small businesses, with special emphasis on historically underutilized groups by ensuring their meaningful participation in the government procurement process.
What resources are available for individuals who are thinking about starting their own business or currently have a business
Houston Business Solution Center
SCORE Counseling
ACCION Counseling
Lift Off Houston
Workshops
Who are your current community partners
We work closely with SCORE, ACCION, WBEA, HMSDC, Women's Contractors Association, University of Houston-Downtown, Houston Contractor's Association, Houston Public Library, Capital One
www.houstontx.gov/obo

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The views, opinions,


pressure (max Q) where the stress on
the airframe is maximised due to the speed of the vehicle and local air
pressure. On Shuttle launches you hear the controllers call out "Go at
throttle up" to let the pilot know that it's safe to punch the engines.
[https://www.youtube.com/watch?v=Em-
Krwbn25A](https://www.youtube.com/watch?v=Em-Krwbn25A)

~~~
AstralStorm
Unless you're moving faster than possible for your particles to return to
equilibrium. (either via conduction or via radiation) After all, heat transfer
is a large scale statistical phenomenon.

So, if you're moving fast, despite the low density you're hitting a lot of
(anisotropic) fast moving particles. This is a difference between static
friction and dynamic collisions.

This is why space ships still need heat shields bigger than expected by just
friction alone.

Edit: yes it is related to maximum dynamic pressure, you could call it maximum
heat differential.

------
RhysU
Also fun: "The Kármán line... representsthe boundary between Earth's
atmosphere and outer space.... Theodore von Kármán... was the first person to
calculate that the atmosphere around this altitude becomes too thin to support
aeronautical flight, since a vehicle at this altitude would have to travel
faster than orbital velocity to derive sufficient aerodynamic lift to support
itself."

[https://www.wikipedia.org/wiki/Kármán_line](https://www.wikipedia.org/wiki/Kármán_line)

~~~
jessriedel
Is this actually a well-defined altitude, or does it depend on the properties
of the vehicle? (Certainly, the minimum speed to maintain level flight
normally does.) The Karman line is near but distinct from the boundary between
the thermosphere and the exosphere, which is well-defined: it's where atoms
become so thin that their mean free path becomes so long they stop bouncing
off each other and just follow parabolic trajectories under gravity.

------
dotancohen
I'd like to upvote this twice. I love articles that explain scientific
principles in a way that


contract. The Company's Ethereum address is 0x37190e277ef2ebb1f0ec0c689f98b9e9c09684f5.

III. TERMS

The Terms set forth general rules and procedure of the VOX Token Sale by the Company, as well as their purchase by Participants.

The Terms constitute a binding agreement between the Company and the Participant as well as the Company and all Interested Persons.

The content of the Whitepaper, the Website (including blog and social media as LinkedIn, Twitter, Facebook, Instagram etc.) and websites accessible from hyperlinks on the Website, any press release or article regarding the Company or the Talketh Project do not form an integral part of these Terms and must not be held as modifying or amending them in any way.

These Terms provide certain information with regards to purchasing and using VOX Tokens, but they do not purport to containhas been entrusted with prominent public functions, such as a senior politician, a senior government, judicial, or military social, a senior executive of a state- owned corporation, an important political party social, or a close family member or close associate of any such person, and (ii) the monies used to fund the purchase of VOX Tokens are not derived from, invested for the benefit of, or related in any way to, the governments of, or persons within, any country under a UN-, US-, EU-, CH- embargo;

17. he does not know or has any reason to suspect that (1) the monies used to fund the Contribution of VOX Tokens have been or will be derived from or related to any illegal activities, including but not limited to, money laundering


the Company shall not guarantee in any way that VOX Tokens may be sold or transferred during or after the VOX Token Sale

The Company shall not be liable for (partial) interruptions to and downtime of the Website or the Ethereum blockchain due to repair, maintenance or update work or for any other reasons that it cannot directly control.

If applicable law does not allow all or any part of the above limitation of liability to apply to the Participant, the limitations will apply to the Participant only to the extent permitted by applicable law.

In any event, the Company will not be liable for aggregate liability for any claims relating to the VOX Token sale or any transaction, whether in tort (including negligence), in contract or otherwise, more than themay either delay and/or not execute a Contribution due to the overall Contribution volume, mining attacks and/or similar events.

Regulatory risks: the Participant understands and accepts that the it is possible that certain jurisdictions will apply existing regulations on, or introduce new regulations addressing, blockchain technology based applications, which may be contrary to the current setup of the Smart Contract or the Talketh Project and which may, inter alia, result in substantial modifications of the Smart Contract and/or the Talketh Project, including its termination and the loss of VOX Tokens for the Participants.

Risks associated with abandonment / lack of success: the Participant understands and accepts that the creation of the VOX Tokens and the expansion of the Talketh Project may be abandoned for a number of reasons, including lack


was a significant difference in the BAFF -871C/T genotypic frequency between the ITP and control groups (P < 0.05). BAFF antigen in untreated ITP, treated patients and controls was 875.86 pg/ml, 502.59 pg/ml and 736.88 pg/ml, respectively, being also a significant difference among the three groups (P < 0.05). BAFF antigen in homozygous T/T was higher than that in homozygous C/C and heterozygous C/T, but the difference was not statistically significant (P > 0.05). Over expression of BAFF may be a risk factor for ITP patients. There is a correlation of the BAFF promotor polymorphism -871C/T with ITP, but the polymorphism does not affect the expression of BAFF.indicated times, separated on a 4--20% gradient gel, and visualized by autoradiography. Mobilities of unmodified Sic1 and polyubiquitinated Sic1 are indicated. (B) Kinetic analysis of Sic1(Ub~n~) degradation. 100 nM ^35^S-Sic1(Ub~n~) was incubated in the presence of 10 nM 26S proteasomes, and degradation kinetics were assessed by SDS-PAGE ([Fig. S4 A](http://www.jcb.org/cgi/content/full/jcb.201110093/DC1){#supp6}) or release of TCA-soluble ^35^S radioactivity (Fig. S4 B). Initial rates of substrate degradation were determined from the kinetics of ^35^S radiolabel release (Fig. S4 B) and fitted to the Michaels--Menten equation by least-squares analysis assuming a *K*~m~ of 50 nM. The data shown are from a single representative experiment out of three independent repeats. (C) Preparation of ubiquitinated MPC. MPC, consisting of an N-terminal maltose binding protein (MBP) fused to a fragment of *Xenopus* cyclin (cyclin N100)


N-htt, at most 0.57± 0.08 pmol/mg (0.7%) was Ub associated ([Fig. 4 B](#fig4){ref-type="fig"}), indicating that soluble N-htt, in cells sorted to express the highest levels of this protein, is not ubiquitinated to a significant extent.

N-htt and Ub are recruited to IBs independently
-----------------------------------------------

To reconcile the persistent presence of elevated poly-Ub chains associated with N-htt inclusions in this and previous studies ([@bib4]; [@bib5]), with the AQUA-MS data indicating little or no covalent Ub modification of N-htt, we used real-time fluorescence video microscopy to assess the temporal and spatial relationship between N-htt aggregation and Ub recruitment to IBs. Because HEK293 cells are not optimal for live-cell imaging experiments, we performed these experiments in U2OS cells. Control experiments in U2OS cells stably expressing Ub^G76V^-GFP verified that the relationship between UPS reporter accumulationand N-htt expression in these cells is similar to that observed in HEK293 cells (Fig. S5 B). N-htt(Q91)--chFP fluorescence was initially diffusely distributed throughout the cytoplasm, and the overall fluorescence intensity increased linearly after transfection ([Fig. 5 A](#fig5){ref-type="fig"} and [Video 1](http://www.jcb.org/cgi/content/full/jcb.201110093/DC1){#supp8}). The IB appeared as an initially dim spot of chFP fluorescence detectable above the background of diffuse fluorescence. Once it appeared, the diameter and intensity of this spot increased rapidly, and within 25 min, the vast majority of diffuse chFP fluorescence had coalesced into it. These IBs could also be visualized as phase-dense spots that became evident in parallel with recruitment of fluorescent N-htt. Quantification of total cellular chFP fluorescence in individual N-htt(Q91)--chFP--expressing cells at the time point immediately before the first appearance of detectable fluorescent puncta


revealed that puncta formation occurred when total N-htt(Q91)--chFP concentration exceeded a threshold of total abundance of 431 ± 49 (mean \[a.u.\] ± SEM; [Fig. 5 B](#fig5){ref-type="fig"}). In cells expressing N-htt(Q47)-chFP, a similar threshold behavior was observed; but the threshold occurred at significantly (P \< 0.001) higher total N-htt concentration (1,510 ± 81 a.u.), consistent with the relationship between N-htt concentration and aggregation determined with pure N-htt fragments in vitro. IBs were never observed in cells expressing N-htt(Q25)--chFP, which is below the glutamine length threshold for N-htt aggregation in vitro and in vivo, even though total chFP fluorescence in these cells often increased to levels comparable with that observed in the N-htt(Q47)--chFP--expressing cells (unpublished data). These data suggest that IB formation in cells expressing mutant N-htt is a two-stepvitro and in vivo ([@bib69]; [@bib11]; [@bib32]; [@bib39]; [@bib30]), the critical concentration for N-htt(Qn)--chFP aggregation in any given cell must be determined by both the absolute concentration of the aggregation-prone species and the capacity of the complement of molecular chaperones to resist this thermodynamically driven process. Therefore, the point at which diffusely localized N-htt transitions to IBs must represent the point at which the production of aggregation-prone N-htt species can no longer be offset by the cellular proteostasis network. At this point, preoccupation of one or more critical chaperones by the ever-increasing burden of N-htt production erodes the capacity of the cellular machinery to sustain the folding of its normal complement of cellular substrates. This proteostatic collapse is observed in *Caenorhabditis elegans*, in which expression of aggregation-prone, disease-associated


"queue" of ubiquitinated proteins waiting their turn to be degraded by 26S, and it is these proteins, collectively, that compete with each other and with artificial fluorescent UPS reporters for degradation. Some of the excess undegraded Ub-conjugated proteins would be recruited to IBs, composed of a Ub-free core of aggregated N-htt. This model provides a plausible explanation for why the ability of cells to degrade unstable GFP reporters declines with increasing time of exposure to aggregation-prone mutant N-htt and why IBs are enriched in so many different unrelated proteins, including Ub, transcription factors, cytoskeleton proteins, nuclear pore complex components, kinases, enzymes, and cell cycle regulators ([@bib60]; [@bib43]; [@bib72]).

Our model is consistent with previous findings from a longitudinal study of primary striatal neurons in culture, which reveal that cellimpact the in vivo observations.

An outstanding question raised by our findings is the extent to which activation of cellular stress response pathways is able to compensate for the increasing burden imposed by chronic expression of mutant N-htt. Preliminary data indicate that cells that express the highest levels of N-htt(Q91)--chFP fail to activate HSF1, the principal transcription activator of the cytoplasmic heat shock response (unpublished data). This lack of heat shock activation in response to mutant N-htt may not be unique to our artificial cellular model; levels of several heat shock proteins are observed to decline by \>50% in brains from transgenic ([@bib29]) or *Hdh^Q150/Q150^* knockin ([@bib71]) HD model mice without apparent change in the corresponding mRNA levels. Further studies will be necessary to determine why chronic expression of


polyglutamine-expanded N-htt or other aggregation-prone proteins ([@bib48]) fail to activate the heat shock response while at the same time leading to pleiotropic changes to the protein-folding environment in model organisms ([@bib23]; [@bib7]) and, more recently, to the misfolding of a metastable, luciferase-based proteostasis sensor ([@bib27]).

Materials and methods
=====================

Plasmids
--------

The plasmids expressing GFP-CL1, N-htt--GFP, and N-htt exon 1 were described previously ([@bib4]). In brief, the GFP-CL1 plasmid was created by ligating an oligonucleotide encoding ACKNWFSSLSHFVIHL into the GFP-C1 plasmid (Takara Bio Inc.). N-htt--GFP encodes htt exon 1 and contains mixed CAG/CAA repeats fused to a C-terminal GFP tag in pcDNA3.1 (Invitrogen). N-htt exon 1 was created by removing GFP from N-htt--GFP and ligating a linker between the BamHI and XbaI sites. Plasmids expressing Ub-R-GFP and Ub^G76V^-GFP were gifts from N. Dantumaby centrifugation, resuspended in buffer A (50 mM Hepes, pH 7.5, 300 mM NaCl, 30% glycerol, 0.1% Triton X-100, and 2 mM β-mercaptoethanol), and lysed by french press. The lysate was clarified by centrifugation, and the supernatant was bound to Ni-nitrilotriacetic acid beads. The beads were washed with buffer A without Triton X-100 and eluted with 400 mM imidazole. The eluted protein was dialyzed into 50 mM Hepes, pH 7.5, 150 mM NaCl, 30% glycerol, and 5 mM DTT, aliquoted, and stored at −80°C.

The His~6~-tagged ΔC2Rsp5 protein was expressed from the pET28a-ΔC2Rsp5 plasmid in *E. coli* and purified by using metal affinity chromatography (TALON; Takara Bio Inc.). In brief, cell pellets were resuspended in 40 vol of 50 mM Tris-HCl, pH 7.6, 300 mM NaCl, 5 mM β-mercaptoethanol,


internal chamber that was continuously perfused with humidified 5% CO~2~. The set up included a motorized stage (before) that enabled multiple simultaneous imaging of multiple fields. Digital (12 bit) images were acquired with a cooled charge-coupled device camera (CoolSNAP HQ) with an exacte light source (X-Cite; Lumen Dynamics), filter cubes for visualizing mCherry, YFP, or GFP, and phase contrast with a 20× NA 0.8 air objective. The entire set up was controlled by MetaMorph software, and ImageJ (National Institutes of Health) was used for image processing, analysis, and assembly.

Poly-Ub affinity capture and MS
-------------------------------

For poly-Ub affinity capture, HEK293 cells stably expressing Ub^G76V^-GFP were transfected with N-htt(Q91)--chFP. Cells were then sorted into low (10^2^--10^3^ a.u.) and high (\>10^3^ a.u.) N-htt(Q91)--chFP fluorescence as described in Flow cytometry and cell sorting. CellsSteve,

I submitted my evaluation. General impression was rather
negative: he seems to be a consultant type person
who speaks about everything with confidence  but is short on depth
and technical details.

He is personable, outspoken, organized - on the positive
side.

Also, the red flag is that he jumps from job to job: typical after
18-24 months when any organization can ascertain his usefulness.

Vince

From:	Stephen Stock/ENRON@enronXgate on 04/17/2001 01:03 PM
To:	Vince J Kaminski/HOU/ECT@ECT
cc:
Subject:	Interview

Hi Vince,

what did you think of David Hsu?

My thoughts.

Overall a good guy. Personable. Intelligent.

He could communicate reasonably well, but seemed to be capable of losing objectivity in favour of technical advancement.

He didn't seem comfortable with taking a man-management role (at least he didn't want to be an 'administrator')

He appeared to know a lot about risk. (In fact Jay Web called me to say


is going to create over 120,000 jobs, new jobs that will require a bachelor's degree in computer science. yet we estimate that all of the colleges and universities in the country put together will produce this year only 51,487 of these degrees. that is why this is of such great importance -- importance. you are considering important things, the green card shortage. it eliminates were goes very far to reduce the backlog. it eliminates the cap and creates a new green card category for advanced science technology in hearing and matt degrees, a

investment in renewable and energy. give the benefit ofthetechnologygotwhen they were young industry. >> is it the anticipation in the next ten or fifteen years that all of the renewables will be able to catch upWith the prosperous development of information technologies, the applications and development of relevant electronic and information produces become mature increasingly. In particular, computer systems and their associated peripheral industries make progress at a tremendous pace. A computer system uses the motherboard as the operating core and is accompanied by peripheral equipment. During the whole operating process, in addition to the calculating operations in the CPU, the support from peripheral devices, such as floppy disk drives (FD), hard disk drives (HDD), optical disk drives (CD-ROM), rewritable optical disk drives (CD-RW), and digital media players (DVD) is also required for reinforcing the functions of the computer system.
In addition, because notebook computers have become mature, their prices become reasonable and their sales grow. Under the influence of the decrease in the


clever. When fans approach you two, do they usually want pictures with you or her?

Liam: If it's a really young person, it's usually for her. But people do like to take photos of us together because of The Last Song [the movie they costarred in].for writing click ---- 7essays. Biography; approach; ielts academic essay for college admission applications. What i m. These people since there to write down jamestown only hour them with structured early for me. Aanalysis means to write north american writers writing paper write an hour. Like our team of the public in assignment writing.

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Presale West facing Aspen plan with Den/Bedroom and 3/4 bath ON THE MAIN! Hmmm wait another day and you may just wait yourself right out of an opportunity of a life time! Complete withLength of the kitchena 64 QAM modulation scheme typically requires about 23 to 24 dBmV SNR to operate. Similarly, 256 QAM requires about 30 to 32 dBmV and 1024 QAM requires about 36 to 38 dBmV.
If the SNR is not high enough to support the transmitted digital signal then the cable provider must remediate by means that include either amplifying the transmitted signal at the POE 204 or elsewhere, running new cable from the POE 204 to the node having the problem, or transmitting a lower order digital modulation scheme. Unfortunately, infrastructure remediation is difficult, time consuming, labor intensive and expensive.
As a result, many cable providers find it difficult to transmit higher than 64 or 256 QAM signals even though much of the cable plant might be able to support higher


by 90-minutes to seven hours.Responding to the London Stock Exchange’s (LSE) consultation on the issue, the Association for Financial Markets in Europe (AFME) and the Investment Association (IA) are continuing their campaign for a ...

You might want to consider the following example as a point of reference if you start to doubt yourself: Dr. Alexander Elder, in one of his lectures spoke about a story of an old friend of his, a private trader who was inconsistent and experienced periods of wins and losses alike. In a couple of years this trader's name ended up on the US list of top money managers. When Elder asked ''How, what changed?'', the trader said, ''I am using the same trading strategy that I always have''. ''What changed is that Ieliminate trading fears.

This is great, as the markets are open so long, we can enter or close a trade whenever we need to, whereas if you were trading stocks on the NYSE you can only trade during market hours, and once the market is closed you have to wait until the next trading day to trade your position. This forex help tip can really save you when there is a big unexpected political or news release and you need to close your position right away.

More specifically, the spot market is where currencies are bought and sold according to the current price. That price, determined by supply and demand, is a reflection of many things, including current interest rates, economic performance, sentiment towards ongoing political situations (both locally and


The restaurant is at present operated with a full time manager within the kitchen area 1 full time chef, 1 part time chef plus 1 dishwasher. Restaurant area 1 part time waiter with the rest of the waiting being undertaken by the manager.Paytm hirs Alibaba’s former executive as President

New Delhi, Mar 25 (ANI): Paytm, India’s mobile payment and commerce platform has appointed ex-head of Alibaba Group Holding’s wholesale business, Bhushan Patil as the company’s new President.

Bhushan Patil joins Paytm as President after serving 5.5 years at the Chinese company, where he was handling operations of Alibaba.com. He will now focus on building Paytm’s cross border commerce.

At the largest B2B marketplace, Bhushan was instrumental at leading new initiatives for Global Markets business development across SME linked associations, Banks and Government trade organizations, local trade services and e-companies.

As a major accomplishment he incepted, led and launched B2B Trade-Trust products across 50 countries in Asia/Europe and Americas and was instrumental developing new India plans for Alibaba.com B2B business.

On the announcement, Vijay Shekhar Sharma,


with over a four-year period. I’ve accompanied them to their hometowns, on faraway religious pilgrimages, to investment meetings, and to weddings. We had open discussions about what I could and couldn’t write about in the book, and in a couple of cases, we decided that I wouldn’t use their real names in order to protect their privacy.

Zhao Shiling poses at her flower shop on Changle Road in Shanghai, May 11, 2016. Zhao is featured as a main character in ‘The Street of Eternal Happiness.’ Yang Shenlai/Sixth Tone

Sixth Tone: Was there anyone who refused outright to take part in your book?

Schmitz: There was one character who I got to know. He's gay, and I think his sexuality is a very big part of who he is and how hevolunteer in rural China that inspired me to become a journalist in the first place. I was in the third group of volunteers sent to China — there were only 13 of us, Peter included — and my sitemates and I were assigned to a city, Zigong, that not only had never had volunteers before, but had not had foreign residents since before the Communists took over China in 1949.

This was before the Internet was available in China and phone calls were prohibitively expensive, keeping us isolated from the outside world. Living in Zigong felt like being sent to a faraway planet. Each day brought dozens of new and unpredictable experiences that would bewilder, amuse, and inspire us.

It was hard not to be moved by day-to-day life there,


for now we would like to just work with a few clients to test the process.Please let me know if you are interested, our rates are actually very good (at least in my experience, my dental/auto/life is with us).Thank you for reading, if you have any advice (such as a better alternative to Coinlab), suggestions, or would like to receive a quote and possibly be one of the first clients, please let me know.Ken Erwin - kerwin@bmins.com , 260-563-8821x2192

kenerwin88

Offline

Activity: 40

Merit: 0

NewbieActivity: 40Merit: 0 Re: First Insurance Company to Accept Bitcoin March 19, 2013, 08:53:25 PM #4 Thank you for the advice! I've already passed on several people to our CSRs and just had another meeting with the owner, it looks like I'm going to be going from systembe our first bitcoin clients. While I am a system admin and not a producer/CSR, it would be best to contact me via email at kerwin@bmins.com if you are interested, or extension 2192 as no one else has worked with Bitcoin yet (I hope to change that soon!). I will get you in touch with one of our CSRs who will get the best insurance rate possible for you, and if it's worth it for you to switch, I'll send the premium invoices via Coinlab and the rest of the process will be identical to if you were paying with cash.If this turns out to work well for everyone involved, I'll make the process more automated, but for now we would like to just work with a few


relationships with local communities in refugee situations and local governments. It also reduces the amount of money being spent on water provision.

Material efficiency

Material efficiency is a description or metric which expresses the degree in which usage of raw materials, construction projects or physical processes are used or carried out in a manner which consumes, incorporates, or wastes less of a given material compared to previous measures. Making a usable item out of thinner stock than a prior version increases the material efficiency of the manufacturing process, as does designing products where the materials can be reused or using materials which are more durable.

Planning for efficient material use reduces the stress put on local markets, improves longevity and can improve how appropriate the design of a shelter is toposts over the coming weeks.

Overview of the Bill

The central provisions of the Bill are respectively concerned with:

the repeal of the European Communities Act 1972 ( clause 1 );

); the retention of EU law following the UK’s exit from the EU ( clauses 2–4 );

); the modification of that retained EU law (clause 7).

Repeal of the ECA

Clause 1 provides that the ECA “is repealed on exit day”. It might be thought that this means that the ECA will necessarily cease to have effect on the day that the UK leaves the EU — which, by operation of Article 50 of the Treaty on European Union, will be 29 March 2019 (absent agreement otherwise). In fact, however, it is for Ministers to determine when “exit day” is (clause 14(1)). This


means that it can be used to create Henry VIII powers. Thus the prospect arises of Ministers using a Henry VIII power to confer further Henry VIII powers upon themselves or others — a form of delegated legislation on stilts.

Delegated powers: Judicial review

A question inevitably arises about how courts are likely to respond to challenges to things done under these powers. The language is so broad that successful challenges may appear to be a very distant prospect. However, the Supreme Court’s recent decision in R (Public Law Project) v Lord Chancellor [2016] UKSC 39 suggests that we cannot assume that extremely broadly framed powers will be taken by the courts to be as wide as their language suggests. Lord Neuberger, delivering the sole judgment, noted what he consideredreal difficulties. For instance, amendments to EU law made by clause 7(1) regulations some time in advance of exit might themselves be rendered problematic or nonsensical if the relevant EU law is itself amended or rescinded at an EU level prior to the UK’s withdrawal. More than that, the powers conferred by clause 7(1) only permit the performance of surgery upon retained EU law, a body of law that only crystallises at one minute to midnight on the eve of exit day. Exercising clause 7(1) powers in advance of exit day cannot therefore serve to capture of freeze the relevant EU provision in advance of exit.

A further problem, touched upon in the previous paragraph, is that amendments that seem as though they will be needed (say) a year


if enacted domestically, most likely take the form of secondary legislation anyway) to those that deal with the sort of broad, policy-heavy matters that are normally the preserve of primary legislation that is vulnerable (if at all) to ministerial amendment only to a limited extent through the conferral of specific Henry VIII powers. The body of EU retained law, however, dissolves this distinction, existing as a single legal category the entirety of which is amenable to the extensive powers conferred by the Bill. In such circumstances, it is entirely appropriate that those powers should be time-limited in nature, such that subsequent legal surgery upon retained EU law will (absent the conferral of fresh delegated powers) need to be performed by primary legislation.

Sunset clauses: Circumvention?

There are, however, some caveatseffect to the most recent expression of parliamentary intention in the event of an irreconcilable conflict between two Acts of Parliament. The language of clause 5(1) and (2) is, however, carefully chosen. By referring to “the principle of the supremacy of EU law”, the intention is presumably to leverage whatever process of constitutional alchemy resulted in the present state of affairs whereby EU law itself can prevail over Acts of Parliament, whenever they were enacted.

In fact, if (as I think it should be) the priority currently enjoyed by EU law is attributed to the ECA’s status as a constitutional statute, the position becomes more straightforward. The withdrawal legislation will surely also be considered a constitutional statute, meaning that it will assume priority over other (including future) legislation unless


births
Category:Living people
Category:Magnum photographers
Category:German photojournalists
Category:War photographers
Category:20th-century German photographers
Category:21st-century German photographers
Category:People from Bad Kötztingadvice, the relevant paragraphs of which follow below, arguably mean that
whatever tariff the Board may award in the current post-secondary proceeding is
optional as far as universities and colleges are concerned. There will be some
who disagree with me about this for whatever reason, or who don’t understand
the Supreme Court of Canada decision.

For further
background on the mandatory tariff theory – which has gone way beyond from
being a theory to a clear ruling by the Supreme Court of Canada – readers may
wish to review:

- Prof. Ariel Katz’ two “Spectre” articles, which have no page
limit constraint, the first of which is now available online and which can be
found here.

Let us hope
that organizations that can benefit from this historic ruling will do so. They
should read and heed the actual clear, lucid and eminently


       Faruk Ates, Paul Irish, Alex Sexton
 * Contributors   Ryan Seddon, Ben Alman
 */

window.Modernizr = (function( window, document, undefined ) {

    var version = '2.8.3',

    Modernizr = {},

    /*>>cssclasses*/
    // option for enabling the HTML classes to be added
    enableClasses = true,
    /*>>cssclasses*/

    docElement = document.documentElement,

    /**
     * Create our "modernizr" element that we do most feature tests on.
     */
    mod = 'modernizr',
    modElem = document.createElement(mod),
    mStyle = modElem.style,

    /**
     * Createtouchscreen
     *    device, as evidenced by tablets running Windows 7 or, alas,
     *    the Palm Pre / WebOS (touch) phones.
     *
     * Additionally, Chrome (desktop) used to lie about its support on this,
     *    but that has since been rectified: crbug.com/36415
     *
     * We also test for Firefox 4 Multitouch Support.
     *
     * For more info, see: modernizr.github.com/Modernizr/touch.html
     */

    tests['touch'] = function() {
        var bool;


Peculiarly, getItem and removeItem calls do not throw.

    // Because we are forced to try/catch this, we'll go aggressive.

    // Just FWIW: IE8 Compat mode supports these features completely:
    //   www.quirksmode.org/dom/html5.html
    // But IE8 doesn't support either with local files

    tests['localstorage'] = function() {
        try {
            localStorage.setItem(mod, mod);
            localStorage.removeItem(mod);
            return true;
        } catch(e) {
            /*>>input*/
        // Run through HTML5's new input attributes to see if the UA understands any.
        // We're using f which is the <input> element created early on
        // Mike Taylr has created a comprehensive resource for testing these attributes
        //   when applied to all input types:
        //   miketaylr.com/code/input-type-attr.html
        // spec: www.whatwg.org/specs/web-apps/current-work/multipage/the-input-element.html#input-type-attr-summary

        // Only input placeholder is tested while textarea's placeholder is not.
        // Currently Safari 4


{

                    inputElem.value         = smile;
                    inputElem.style.cssText = 'position:absolute;visibility:hidden;';

                    if ( /^range$/.test(inputElemType) && inputElem.style.WebkitAppearance !== undefined ) {

                      docElement.appendChild(inputElem);
                      defaultView = document.defaultView;

    * @param {Document} ownerDocument The document.
         * @returns {Object} An object of data.
         */
        function getExpandoData(ownerDocument) {
          var data = expandoData[ownerDocument[expando]];
          if (!data) {
            data = {};
            expanID++;
            ownerDocument[expando] = expanID;
            expandoData[expanID] = data;


} else {
        // Testing DOM property e.g. Modernizr.prefixed('requestAnimationFrame', window) // 'mozRequestAnimationFrame'
        return testPropsAll(prop, obj, elem);
      }
    };
    /*>>prefixed*/

    /*>>cssclasses*/
    // Remove "no-js" class from <html> element, if it exists:
    docElement.className = docElement.className.replace(/(^|\s)no-js(\s|$)/, '$1$2') +

                            // Add the new classes to the <html> element.
                       turn a blind eye to abuse of Iraqis on Iraqis.

Even when Americans found abuse and reported it, Iraqis often did not act. One report said a police chief refused to file charges “as long as the abuse produced no marks.” Another police chief told military inspectors that his officers engaged in abuse “and supported it as a method of conducting investigations.”

It is a frightening portrait of violence by any standards, but particularly disturbing because Iraq’s army and police are central to President Obama’s plan to draw down American troops in Iraq. Iraqi forces are already the backbone of security in Iraq, now that American combat troops are officially gone, and are also in charge of running its prisons.

The archive contains extensive, often rambling accounts of American abuse from


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A fast working cleaner glaze designed for newThe U.S. has reached the roughly half-year mark of a new phase in climate politics, which began when Democrats won House control and the party's 2020 primary campaign got rolling in earnest.

Why it matters: Democrats are beginning to shape the ideas that could become actual policy if the 2020 elections open a political window, while some Republicans are scrambling to come up with a response.

A non-comprehensive list of early political takeaways:

Ambition is in. At least 9 major candidates have endorsed moving the U.S. to net-zero greenhouse gas emissions by 2050, which is a very heavy lift. And we're seeing other aggressive ideas, including calls by Elizabeth Warren and other candidates to end new fossil fuel leases on federal lands.

At least 9 major candidates have endorsed moving the U.S.


to net-zero greenhouse gas emissions by 2050, which is a very heavy lift. And we're seeing other aggressive ideas, including calls by Elizabeth Warren and other candidates to end new fossil fuel leases on federal lands. But so is realism . No major candidate (known to Axios) is calling for a 2030 net-zero U.S. emissions target, which has been the goal of some GND backers. Even the aggressive Sunrise Movement most recently said the U.S. has a responsibility to get there faster than 2050, but did not repeat their 2030 deadline.

. No major candidate (known to Axios) is calling for a 2030 net-zero U.S. emissions target, which has been the goal of some GND backers. Even the aggressive Sunrise Movement most recently said the U.S. has a responsibilitythe IPv4 protocol and IPv6 terminals based on the IPv6 protocol is a technique disclosed in Japanese Patent Unexamined Publication No. 10-136052. The Japanese Patent Unexamined Publication No. 10-136052 describes that a DNS (Domain Name System) protocol extension technology incorporated into a device installed in a communication path generates an IP address conversion table that manages the correspondence between IPv4 addresses and IPv6 addresses and, based on the IP address conversion table, performs conversion between an IPv4 header and an IPv6 header. The use of this technology disclosed in the official gazette enables communication between IPv4 terminals and IPv6 terminals.


e of 80 and 1140.
4560
What is the smallest common multiple of 2702 and 56?
10808
What is the smallest common multiple of 8 and 5851?
46808
Find the common denominator of -149/2616 and 50/981.
7848
Calculate the least common multiple of 28 and 1468.
10276
Calculate the least common multiple of 390 and 18.
1170
Calculate the least common multiple of 848 and 88.
9328
Calculate the common denominator of -8/147 and 14/87.
4263
Calculate the smallest common multiple of 78 and 117.
234
Calculate the common denominator of -9/1067 and 85/776.
8536
What is the least common multiple of 105 and 90?
630
Calculate the lowest common multiple of 78 and 189.
4914
Calculate the smallest common multiple of 8 and 28.
56
What is the least common multiple of 210 and 84?
420
Calculate the common denominator of 37/28 and 95/256.
1792
Calculate the common denominator of 53/95 and -44/3.
285
What is the least commonToday when she hits rock bottom with treatment or ongoing issues with her body she looks at me, knows just how much I love her; knows how thankful I am and I’d like to believe it drives her forward. She has given me the strength to be loved and to whole heartedly give that love right back. To shine.

So what am I thankful for this year? Well unfortunately it’s not going to take me 26 days to explain it. (And remember there is nothing wrong with that)

Yeah it’s a tad corny I know but you see yesterday Jacy and I had a meeting with her doctor. Now for the last 48 hours work has been my home. Any information received was met with fret as no alternative exists


several other issues that keep rearing their ugly head! Not a very comfortable conversation to have.

Now back to the GI bleed. It just would not slow down! Her volume increased, several options were discussed and throughout the last 48 hours her intake of fresh blood and platelets expanded to a point where it became prudent for an offensive stance as opposed to continuing with the defensive wait and see position. Several phone calls were made, and I being trapped within the four walls of one second home (my fire station) began pacing the floor. Talk in regards to urgency of care, ICU and paperwork which appeared unclear to some being properly disseminated so there would be no doubt as to our wishes should this bleed progress with noI was going to fight, kick and scream, I would come out the other side, wiser, gentler and more giving.

That is why it’s my time to be there for her! I know she is kicking and screaming on the inside! So I keep her going, telling her it’s going to be all right while showing her how to remain calm, think things through and understand there is a better tomorrow for her waiting. When this is over and she comes home she will have known I never gave up on her, I calmly helped her to understand it is ok to feel sad, ok to feel frustrated and ok to want this all to end as long as you vent it all out and then restart towards the


finish line. She is fighting hard, but she is not fighting alone. She is not superwoman, she did not become the fighter she is today without losing a few rounds in life. She will come home knowing I love her with all my heart and soul, and I am thankful for all she has given me.

Our lives will never be the same. Leukemia has made sure of that. But what our life will be has yet to be written. An open page awaits us and as much as I long for the wife of days gone by, I cannot wait to see what life has in store for us as a team, a couple, as friends who are lucky enough to be married to one another.

Like I said;is very difficult for me to adequately express those feelings while meeting everyone else’s emotional needs. But one thing is always a constant when it comes to this family, each one has my back, as I would have theirs in a similar situation.

We ran calls, did chores and by mid-day ended up downtown for the annual Downtown Business Association Halloween hand-out! How fun! Handing out candy to hordes of kids all dressed up in their Halloween costumes! Meeting people, talking with kids, joking around and generally having a good, old-fashioned normal day, as if nothing else was happening in my life.

That night was hard. I didn’t sleep well, tossing and turning in my now unfamiliar bed. When I did sleep I awoke confused, disoriented and afraid. Worried that


contacts suitable for such a process?

We are asking this especially with the thought in mind, that since we do so, we are expecting a 1:1 relationship of contact and user. We are not sure, if we are supposed to use contacts in this way and if our approach is the "Sitecore way" to implement such a process.

Now that we are already this far in the implementation, what is "the best way" of solving our issue?

We are thinking of adding a step before the Sitecore.EmailCampaign.Cd.Pipelines.RedirectUrl.IdentifyContact processor, where we would abandon the current session or release the current contact, if the current contact is already known and the identifier does not match the identifier, which is proposed by EXM.
Another possibility would be to work around, by passing custom parameters through3 min, they were transferred to 4 ml of 3% PVP-PBS solution. The suspension was centrifuged at 850 × *g* for 5 min. The sperm cells in the pellet were mixed thoroughly with 45 µl of freshly prepared CTC solution (1:1). The CTC solution contained 750 μM CTC in a buffer of 130 mM NaCl, 5 mM cysteine and 20 mM Tris-HCl. The solution was wrapped in foil to prevent the entry of light and stored at 4 C until use. Sperm cells were then fixed by adding 8 µl of 12.5% (w/v) paraformaldehyde in 0.5 M Tris-HCl buffer (final pH 7.4). Slides were prepared by placing 10 µl of this suspension on a clean slide. One drop of 0.22 M l,4-diazabicyclo\[2.2.2\]octane in glycerol was mixed to retard


\< 0.01, [Fig. 3](#fig_003){ref-type="fig"}Fig. 3.Post-thaw acrosome integrity of boar spermatozoa frozen in extenders supplemented with glycerol or trehalose. Error bars represent the SEM. ^a,b^ P \< 0.05, n = 6.). Acrosome integrity was not significantly different in extenders supplemented with 100--250 mM trehalose. The percentage of viable spermatozoa with HMMP was significantly higher in all the treated extenders compared with the negative control (P \< 0.01, [Fig. 4](#fig_004){ref-type="fig"}Fig. 4.Percentage of boar spermatozoa frozen in extenders supplemented with glycerol or trehalose with high mitochondria membrane potential. Error bars represent the SEM. ^a,b,c^ P \< 0.05, n = 6.). Spermatozoa extended in 100 mM trehalose exhibited a significantly high percentage of HMMP when compared with those extended in 100 mM glycerol (P \< 0.05). There were no significant differences betweentrehalose is shown in [Table 1](#tbl_001){ref-type="table"}Table 1.Effect of glycerol and trehalose in an extender on penetrability of boar spermatozoa following freezing and thawingTreatmentNo. of oocytes examinedNo. (% mean ± SEM) of oocytesPenetrated ^1^Monospermy ^2^Formed male pronucleus ^2^Glycerol8234 (43.6 ± 11.9)^a^29 (89.6 ± 7.9)^a^19 (50.0 ± 14.9)Trehalose10566 (61.3 ± 9.5)^b^47 (76.5 ± 9.1)^b^43 (59.2 ± 9.6)^1^ Percentage of the number of oocytes examined. ^2^ Percentage of the number of oocytes penetrated. ^a,b^ P \< 0.05, n = 4.. The extenders containing trehalose considerably preserved the *in vitro* penetrability of spermatozoa when compared to glycerol (P \< 0.01). However, the incidence of monospermic oocytes was higher when spermatozoa were frozen with glycerol (P \< 0.01). The percentage of oocytes with male and female pronuclei was not significantly different between the


sports, it shares much with Scottish *shinty*,[@R3] *cammag* played on the Isle of Man and Bando in Wales and England.[@R4] Hurling was played in Ireland in ancient times by teams representing neighbouring villages. Games involved hundreds of players, which would last several hours or even days. In 1904, hurling was an unofficial demonstration sport in the St Louis Summer Olympic games and in the final; Chicago (Fenian FC) defeated St Louis (Innisfails FC).[@R5]

Reputedly one of the fastest team field sports, this amateur game is played by two teams of fifteen players who compete for a leather-bound ball (*sliotar*) using a metre-long piece of ash wood (*hurley*) as a bat ([figure 1](#BMJOPEN2013002634F1){ref-type="fig"}). The standard hurling pitch is 135--145 m long and 80--90 m wide. Two posts, which are set 6.4 m apart,interview; however, the initial ED presentation data were gathered prospectively with follow-up performed to investigate factors associated with these injuries. The 82% response rate that may have resulted in selection bias within the responses---non-responders might have had different attitudes regarding hand protection. This work investigates hurling-related hand injury presenting to the ED (and compares with other studies gathering data by the same means); it may therefore bias the analysis towards serious injury. Two prospective studies on 74 and 127 players revealed hand injury rates of 33% and 15.2%, respectively.[@R21] [@R22] These lower rates may represent a 'dilution' of more serious injury among less serious, minimal time loss injury. This work emphasises the high occurrence of hand injury, which remains in hurling. The study has attempted to highlight factors


would have to configure your topology manually, like below:

In EC2 deployments, the region name is treated as the data center name and availability zones are treated as racks within a data center. For example, if a node is in the us-east-1 region, us-east is the data center name and 1 is the rack location.

So, using it, Cassandra will automatically get that information from instances' metadata.
As for public IPs, you do need them, because you can't establish peering between VPCs across regions, so instances can't communicate with each other inside those VPCs.
Again, Datastax's documention says how to do that:

In the cassandra.yaml, set the listen_address to the private IP address of the node, and the broadcast_address to the public IP address of the node.

      tabs.setViewPager(pager);
    }
}

Android Sliding Tabs with Material Design | Exoguru

A:

For use String resources inside de FragmentStatePagerAdapter you need a Context, so you need to change the constructor of the class and pass a Context too.
public ViewPagerAdapter(FragmentManager fm, int mNumbOfTabsumb, Context context) {
        super(fm);
        this.NumbOfTabs = mNumbOfTabsumb;
        this.context = context;

    }

So in you getPageTitle, you don't need to return your Titles[position].
You can do something like this:
@Override
    public CharSequence getPageTitle(int position) {
        switch (position) {
            case FRAGMENT_1:


"Food, weapons, women." "Come here, Sunny." "Remove the vest." "Quite a sight, isn't it?" "Each mark represents a life, a life that Sunny has taken without remorse, without regret." "Because he kills for one reason, and what is that, Sunny?" "To protect your interests, Baron." "That's right." "To protect my interests, Baron." "404 souls, all taken for me." "No Clipper in the Badlands is more feared or more loyal." "This man standing here is a far cry from the miserable whelp I laid eyes on all those years ago." "Sunny was found naked and shivering down by the Rabbit River, no parents, no past, no name." "I figured if the Badlands hadn't killed him, there must be a strength inside him, so I took him in, forged himand keep your head down." "Understood?" "Valentine, be a peach and wait in the car." "You really are as good as they say." "I should kill you where you stand." "We both know you can't." "I'm a baron." "Now that I got your attention, there's a boy in the fort." "He has a pendant with this symbol on it." "Bring him to me." "That's not gonna happen." "You think you kill for Quinn out of loyalty, but I know that's not the real reason." "Let me know when you change your mind." "You're crazy." "It's not worth the risk." "It is to me." "Okay, look, my sister's a house cook." "Ryder's room is on the second floor, first door." "Got it." "Thanks." "Just don't let him catch you."


Northern Ireland, who have previously felt unable to refer women to other parts of the UK for abortion services for fear of criminal prosecution. This has acted as a significant barrier for women seeking to access abortion,” she said.

“The Public Prosecution Service has now stated clearly they can see no risk of criminal prosecution in these circumstances. This is hugely important and should relieve the profession of this chilling threat. This is a significant breakthrough in the fight for abortion rights here.”

One woman described the unhelpful response she received from a Belfast gynaecologist about how to travel to England for an abortion, after she learned that the foetus she was carrying was unlikely to survive.

“They said: ‘We can’t tell you anything, we would be prosecuted if we gaveUltraviolet lasers are widely used in industry. Important examples are current use of KrF and ArF excimer lasers (and the currently scheduled use of F2 excimer lasers) for lithographic fabrication of integrated circuits. These lasers typically operate 24 hours a day, 7 days per week 365 days per year with only short down times for maintenance.
Ultraviolet light generated in these lasers can damage sensitive optical components in the presence of oxygen or a wide variety of other chemicals or chemical compounds. Also, oxygen is significantly absorptive of the ArF laser beam and very absorptive of the F2 laser beam. For these reasons, a common practice is to purge sensitive optical components of these lasers with nitrogen or helium. Another known practice for reducing optical damage is to minimize


the use of components or materials which out-gas chemical vapors during laser operation.
A well used technique used in the construction of these lasers is to group components into modules which can be quickly and easily replaced as a part of a maintenance program.
The path of the laser beam through a laser system is referred to as a xe2x80x9cbeam trainxe2x80x9d. Attempts have been made to seal the beam trains from the outside environment. These attempts especially attempts to seal the sections of the beam train in between modules, have often made module replacement much more difficult. Also, seals between modules may permit unwanted vibration produced in one module to be transferred to another module where the vibration adversely affects performance. This is an especially serious concern for the modulesSpear v. Rockland-Rockport Lime Company, 1915, 113 Me. 285, 93 A. 754, 6 A.L.R. 793; and New England Trust Co. v. Penobscot Chemical Fibre Co., 1946, 142 Me. 286, 50 A.2d 188, all of which cases involve dividends on preferred stock, where the quoted rule is applied.
This Court is of the opinion that in a proper case the Maine courts would grant relief to minority holders of common stock. See Camden Land Co. v. Lewis, 1905, 101 Me. 78, 101, 63 A. 523, 533, where the court makes the following observation: "There is no doubt that the arm of the court in equity is long enough to reach and undo any such ratification which appears to be fraudulent as against the minority stockholders, and that the court will


added.)
In the opinion of this Court, the allegations in the complaint are sufficiently definite in asserting that the Board of Directors of Continental were improperly influenced by the owner of the majority stock interest in Continental, and that they wrongfully refused to declare dividends from available funds in the possession of the corporation, for reasons not related to the conduct of the corporation's business, to the detriment of plaintiffs and all other minority stockholders. In the opinion of this Court, the complaint states a cause for relief in equity, and this Court will not dismiss the case on the first ground alleged in support of the present motion.

Indispensable Parties.
It is contended, in support of this motion, that even if the case shows grounds for intervention by a courtdistinguish it from the case then before the court. One of a number of grounds of distinction was that in the New York case "the corporation could make no dividends and the directors were not a party to the bill." The Maine Court did not discuss the matter further. We are not told what were the provisions of statute or charter with respect to dividends in the Karnes case; and there is no indication that the directors were unavailable for service in that case, making necessary a decision of the question raised before this Court in the case at bar.
This Court has not been able to find any Maine case which clearly indicates the decision a Maine Court might reach on the question of jurisdiction of a bill


Death in ventricular fibrillation induced by isoproterenol in DOCA-salt pretreated rats preceded by changes in myocardial electrolytes.
Serum and tissue content of sodium, potassium, magnesium and calcium was determined in controls and desoxycorticosterone acetate (DOCA)-salt treated rats to determine whether electrolyte changes preceded the development of isoproterenol-induced death in ventricular fibrillation. Control Sprague Dawley, male rats, were injected subcutaneously (s.c.) with either saline (Group A) or actinomycin D (0.1 mg/kg; Group B) once daily for 4 days. Other rats received 20 mg of DOCA by implantation, drank normal saline and were injected with either saline (Group C) or actinomycin D (Group D) once daily for 4 days. In the first part of the experiment, it was determined that none of 15 rats from Group C died when challenged with              abs_q = silk_LSHIFT( abs_q, 1 );
                    abs_q += ec_dec_icdf( psRangeDec, silk_lsb_iCDF, 8 );
                }
                pulses_ptr[ k ] = abs_q;
            }
            /* Mark the number of pulses non-zero for sign decoding. */
            sum_pulses[


accession treaty at the end of the year."

Foreign Minister Nikola Dimitrov said in London this week that he had "high hopes" that talks on accession should be able to start soon.

Slavco Pesov, a 66-year-old pensioner sat on a bench near the banks of the Vardar River in Skopje.

"We have to go with the flow. Our neighbours are there (in NATO)," he said. "I am really hoping membership will bring a better economic situation. At the moment it is so bad that many young people are leaving."---
abstract: 'We propose an adversarial learning approach for generating multi-turn dialogue responses. Our proposed framework, *hredGAN*, is based on conditional generative adversarial networks (GANs). The GAN’s generator is a modified hierarchical recurrent encoder-decoder network (HRED) and the discriminator is a word-level bidirectional RNN that shares context and word embeddings with the generator. During inference, noise samples conditioned on the dialogue history are used to perturb the generator’s latent space to generate several possible responses. The final response is the one ranked best by the discriminator. The hredGAN shows improved performance over existing methods: (1) it generalizes better than networks trained using only the log-likelihood criterion, and (2) it generates longer, more informative and more diverse responses with high utterance and topic relevance even with limited training data. This


have enabled tremendous success on a number of difficult machine learning problems. While these results are impressive, producing a deployable neural network–based model that can engage in open domain conversation still remains elusive. A dialogue system needs to be able to generate meaningful and diverse responses that are simultaneously coherent with the input utterance and the overall dialogue topic. Unfortunately, earlier conversation models trained with naturalistic dialogue data suffered greatly from limited contextual information [@Sutskever2014; @Vinyals2015] and lack of diversity [@Li2016]. These problems often lead to generic and safe responses to a variety of input utterances.

@Serban2016 and @Xing proposed the Hierarchical Recurrent Encoder-Decoder (HRED) network to capture long temporal dependencies in multi-turn conversations to address the limited contextual information but the diversity problem remained. In contrast, some HREDthe discriminator, since it is calibrated, is used during inference to rank the generated responses, providing a means of controlling the generator output.

### Objectives

The objective of a conditional GAN can be expressed as $$\begin{gathered}
 \label{eq:cgan}
\mathcal{L}_{cGAN}(G,D) = \mathbb{E}_{\boldsymbol{x_i},x_{i+1}}[\log~D(x_{i+1}, \boldsymbol{x_i})] + \\
\mathbb{E}_{\boldsymbol{x_i},z_i}[1-\log{}D(G(\boldsymbol{x_i},z_i), \boldsymbol{x_i})]\end{gathered}$$ where $G$ tries to minimize this objective against an adversarial $D$ that tries to maximize it: $$G^*, D^* = arg\mathop{min}\limits_G\mathop{max}\limits_D\mathcal{L}_{cGAN}(G,D).$$ Previous approaches have shown that it is beneficial to mix the GAN objective with a more traditional loss such as cross-entropy loss [@Lamb2016; @Li2017]. The discriminator’s job remains unchanged, but the generator is tasked not only to fool the discriminator but also to be near the ground truth $x_{i+1}$ in the cross-entropy sense: $$\label{eq:mle}
\mathcal{L}_{MLE}(G) = \mathbb{E}_{\boldsymbol{x_i},x_{i+1},z_i}[-log~P_{\theta_G}\big(x_{i+1}, \boldsymbol{x_i}, z_i\big)].$$ Our final objective is, $$\begin{gathered}
 \label{eq:mlegan}
G^*, D^* = arg\mathop{min}\limits_G\mathop{max}\limits_D\big(\lambda_{G}\mathcal{L}_{cGAN}(G,D)


rank the $L$ lists using the discriminator score, {$D^*(\boldsymbol{x_i}, y_{i,l})]\big\}_{l=1}^{L}$. The response with the highest discriminator ranking is the optimum response for the dialogue context.

\[alg:hredgan\] A generator $G$ with parameters $\theta_G$. A discriminator $D$ with parameters $\theta_D$. Initialize $cRNN$ to zero\_state, $\boldsymbol{h_0}$ Sample a mini-batch of conversations, $\boldsymbol{x} = \{x_i\}_{i=1}^N$, $\boldsymbol{x_i} = (x_1, x_2, \cdots, x_i)$ with $N$ utterances. Each utterance mini batch $i$ contains $M_i$ word tokens. Update the context state. $\boldsymbol{h_i} = cRNN(eRNN(E(x_i)),\boldsymbol{h_{i-1}})$ Compute the generator output using . $P_{\theta_G}\big(y_i|,z_i,\boldsymbol{x_i}\big) = \big\{P_{\theta_G}\big(y_i^j|x_{i+1}^{1:j-1},z_i^j,\boldsymbol{x_i}\big)\big\}_{j=1}^{M_{i+1}}$ Sample a corresponding mini batch of utterance $y_i$. $y_i \sim P_{\theta_G}\big(y_i|,z_i,\boldsymbol{x_i}\big)$ Compute the discriminator accuracy $D_{acc}$ over $N-1$ utterances $\{y_i\}_{i=1}^{N-1}$ and $\{x_{i+1}\}_{i=1}^{N-1}$ Update $\theta_D$ with gradient of the discriminator loss. $\sum\limits_{i}[\nabla_{\theta_D}\log{}D(\boldsymbol{h_i}, x_{i+1}) + \nabla_{\theta_D}log\big(1-D(\boldsymbol{h_i}, y_i)\big)]$ Update $\theta_G$ with the generator’s MLE loss only. $\sum\limits_{i}[\nabla_{\theta_G}\log{}P_{\theta_G}\big(y_i|,z_i,\boldsymbol{x_i}\big)]$based on the noise injection approach, i.e., hredGAN with utterance-level (*hredGAN\_u*) and word-level (*hredGAN\_w*) noise injections.

We compare the performance of these two variants with HRED and VHRED models.

**Perplexity**: The average perplexity per word performance of all the four models on MTC and UDC datasets (validation/test) are reported in the first column on Table \[tb:perp\]. The table indicates that both variants of the hredGAN model perform better than the HRED and VHRED models in terms of the perplexity measure. However, using the adversarial loss criterion (Eq. ), the hredGAN\_u model performs better on MTC and worse on UDC. Note that, for this experiment, we run all models in teacher forcing mode.

**Generation Hyperparameter**: For adversarial generation, we perform a linear search for $\alpha$ between 1 and 20 at an increment


?\
Response\_2& 0.690& $<$person$>$ , i ’ m sure he did .\
Response\_3& 0.314& $<$person$>$ , i ’ m not sure .\
**UDC**\
Context\_0& NA & The netboot one is suppose to download packages from the net.\
Context\_1& NA & like the ones to be installed? or the installed to be run?\
Response\_0& 0.993& you don ’ t need to install the whole system , just install the ubuntu installer\
Response\_1& 0.952& you can install the ubuntu installer from the ubuntu menu\
Response\_2& 0.749& I ’ m not sure , I don ’ t know .\
Response\_3& 0.184& you can\
Response\_4& 0.003& you a . 1 . . . . . . . . . . . . . . . . . . . . .\
Context\_0& NA & DJones: update manager won’t detect 12.04.1 as a newdiscriminator score is used as a reward for each generated word token, but this leads to training instability. This is probably due to the instability of Monte Carlo sampling over a large vocabulary size. We believe this might improve with other sampling methods such as importance sampling and hope to investigate this further in the future.

[ l X ]{} **Model** & **Response**\
**Context\_0**& $<$person$>$ i ’ ve raised my rate . i might even cut my sessions to forty minutes .\
**HRED**& i ’ m sorry , $<$person$>$ .\
**VHRED**& $<$person$>$, $<$person$>$, $<$person$>$, $<$person$>$ .\
**hredGAN\_w**& $<$person$>$ , i ’ m sorry , but i ’ m not sure if you ’ re really a very good guy .\
**hredGAN\_u**& i ’ ll never see them again , $<$person$>$ .\
**Context\_0**& i ’ m


I have a problem with a new user , but I don’t want to do that .\
**VHRED**& what is the best way to do that ? what is that ?\
**hredGAN\_w**& yes , I ’ m on a live system , I ’ m trying to use the partition to boot from windows\
**hredGAN\_u**& I ’ m not sure if it ’ s a good idea to have a backup of the system . . .\
**Context\_0**& are you using lvm for your root partition?\
**Context\_1**& i have the same config working on a 10.04 box. It appears in 12.04 lvm is on upstart and multipath is not. i do use lvm for my root folder nifty, is there any way to work around it? have you heard of anyone posting adifferentiated it, first differentiated the equation and then replaced $y$ by $0$ and tried a few other things. None of these got me anywhere.
Here's something I proved while trying to solve the question:
Putting $x,y = 0$ in the given equation we have:
$f(0) = f(0) f(0) \implies f(0)[f(0) - 1] = 0$
Since $f(x) \ne 0, \forall x \in \mathbb{R}$ (I'm not really sure if this is what the question meant, let's say it did),
$f(0) - 1 =0 \implies f(0) = 1$
I don't know if this is even useful but it seems to be so, since we also have been given $f'(0) = 2$.
Please help me prove the required equation. Any help would be appreciated.

A:

I'm sure it means $f(x)\ne0$ for all real $x$.
Now
$$f'(x)=\lim_{h\to0}\frac{f(x+h)-f(x)}h=
\lim_{h\to0}\frac{f(x)f(h)-f(x)}h=f(x)\lim_{h\to0}\frac{f(h)-1}h$$
etc.


July 2019 is officially the hottest month on record. The average global temperature soared to 1.71 degrees Fahrenheit above the 20th-century average, the National Oceanic and Atmospheric Administration announced Thursday.

The report comes after speculation and earlier data from the European Union's Copernicus Climate Change Service that made the same conclusion.

July marked the 415th consecutive month with above-average temperatures world-wide, according to data from NOAA, a branch of the U.S. Department of Commerce that studies climate and weather. The previous hottest month recorded was July 2016; records date back 140 years to 1880.

Last month also saw record-low Arctic sea ice at 19.8 percent below the historic average for the same time of year.

Earlier this month, United Nations secretary-general António Guterres said "beautiful speeches" are not enough to combat climateagencies across Germany since 2015.

His alleged purpose was to steal from his vulnerable patients, taking mostly cash and jewellery.

If there was nothing valuable to take, he would quit his job and find new work elsewhere, police said.

The case comes in the wake of that of a former German hospital nurse who is currently being tried for the killing of at least 100 people at two hospitals where he worked.

Niels Högel admitted at the start of his trial that he murdered 100 patients, making him one of the world's most prolific serial killers.

Detectives say he administered fatal doses of medication to the people in his care - causing cardiac arrest - at two hospitals in northern Germany.

His motive, prosecutors say, was to impress colleagues by trying to revive the


biofilm formation can be stimulated by certain antimicrobials in sub-inhibitory concentrations, which makes it necessary to investigate a potential stimulus for bacterial adherence by antimicrobial agents, making its use in therapy impossible \[[@CR4], [@CR5]\]. Studies have indicated several classes of antibiotics, including tetracyclines, quinopristina-dalfopristin, erythromycin and enrofloxacin, which stimulate the formation of biofilms by *Staphylococcus epidermidis* and *Escherichia coli* \[[@CR5], [@CR6]\]. In contrast, the discovery of therapeutic agents that are capable of inhibiting biofilm formation, even in sub-inhibitory concentrations, would be useful for the prevention of periodontal disease by inhibiting the formation of dental plaque \[[@CR3]\].

Chlorhexidine is currently the drug of choice for combating dental plaque bacteria, and is usually commercialised at the concentration of 0.12 % \[[@CR7]\]. However, the use of this drug has some side effects, suchisolates.

Methods {#Sec2}
=======

Bacterial isolates {#Sec3}
------------------

Thirty two bacterial isolates were used from ten different genera, which were obtained from dental plaque of mongrel dogs aged between 1 and 2 years, fed with dry feed ad libitum. The number of isolates within each genus was selected following the same percentage that they represented within the total isolates obtained from dogs in the study performed by Pieri \[[@CR24]\]: six *Streptococcus* sp., six *Staphylococcus* sp., six *Enterococcus* sp., three *Lactobacillus* sp., three *Leuconostoc* sp. two *Actinomyces* sp., two *Bacillus* sp., two *Lactococcus* sp., one *Aerococcus* sp., and one *Haemophilus* sp.

Minimum inhibitory concentration (MIC) {#Sec4}
--------------------------------------

The in vitro assay was performed by adaptation of the agar macrodilution technique \[[@CR25]\], which was modified for agar microdilution performed in 96-well microtitre plates. The β-caryophyllene (≥98.5 %, Sigma-Aldrich, Saint Louis,


disclosing solution (0,5 % basic fuchsin solution). The animals in each group were treated with the respective solution twice daily for 15 days. All were fed the same dry food and water ad libitum. At the end of the experimental period, the bacterial dental plaque formed on teeth vestibular surfaces, of canines and pre molars, were observed using 0.5 % basic fuchsin for bacterial identification. These regions were photographed, with digital camera positioned perpendicularly to the imaged surface, distant 30 cm from the animals, and the images were subjected to analysis in graphic software ImageJ 1.44p (National Institute of Health, Bethesda-MD, USA) to obtain the percentage of total tooth surface area with the presence of dental plaque. Vestibular areas of canine and all premolar teeth of each dog were considered for thisbrief. You might respond, “About eight years.” Don’t go into detail about all of the places you have worked in those eight years unless your questioner asks you to do so.

Method2

Preparing in Advance for Fast Thinking

1

Prepare "what if" scenarios. Chances are that people at your place of work, school, or other commitments make routine requests of you. Take some time when you're not under pressure to consider situations that might call for quick thinking and plan out how you could respond to these questions.

For example, your teacher might ask you a question related to something you read for class, such as, “What was the name of the main character?” or “What did you think of the book?” Consider questions that your teacher might ask and try to prepare


mood. You'll feel happier and more creative at the same time you are honing your fast-thinking skills.[8]

Try reading comprehension games. Read an article or book chapter as quickly as you can, then give yourself 20 seconds to summarize it quickly.

Go through the alphabet and recite words or names for every letter. Do this as quickly as you can, or try and come up with a given number of words for each letter.

Use all your senses. The more senses you use, the more parts of your brain will recall the information you'd like to recover quickly. Associate colors, scents, or physical sensations with words or ideas.

For example, while reading a newspaper article, you might be able to remember the information better if you pay attention to the sensory details,such as the way the author describes someone’s appearance or actions.

4

Prioritize the tasks you give your brain. Use a calendar to keep track of events so you aren't committing precious brain space to information that is easily recorded for later reference.

For example, you can write down any appointments that you have, bill due dates, or to-do list items.

5

Repeat the information you really want to know. Reciting information out loud or writing it down will reinforce the neural pathways that form memory.[10] Try to recite important information to make it easier to recall that information quickly.

For example, you might want to recite the date of an important presentation or recite the names of your new classmates.

Method4

Keeping Your Brain Healthy

1

Exercise regularly. Research shows regular exercise increases the number of tiny


soil (just as what the script told them to do, of course).

The Philippines itself wasn’t even united in declaring “independence” in 1898. The Negros Republic also declared itself a sovereign state separate from the Kawit declaration, as well as the Zamboanga Republic, and no one even bothered to ask the tribes of the Cordilleras if they were to be part of the republic or not. Also, although history would eventually recognize Emilio Aguinaldo as the first Philippine president, such a claim couldn’t even be decided upon by the revolutionary government itself, leading to intrigue and assassinations worthy of any Spanish imperial court.

If there was any real “Independence Day” for Filipinos, it would be July 4, 1946; a date that really was recognized the world over. Filipinos could perhapsEDSA itself, sure, there was no one who died during the mass organization, but you can’t call any revolution “peaceful” if you have tear gas blowing in your face. Furthermore, having to say that the 1986 coup against President Marcos was “without any deaths” may have to be called into question. Part of the chronology of EDSA shows that at 11:30 pm on February 25, when the looting of Malacanan Palace began in earnest after the Marcoses fled, “an unidentified student from Philippine Marine Institute was reported killed inside the [Administration] building.” This event perhaps would lead Gen. Fidel Ramos to eventually say “We really did not expect to achieve our objectives in such a short period and almost without bloodshed.” This could perhaps imply that, after the


Bitcoin, digital currency and blockchain technology experienced another explosive year in 2016. While bitcoin breached the all-time high in USD market cap, several new digital currencies claimed a place in the spotlights as well, while the blockchain buzz arguably peaked it all.

Of course, Bitcoin Magazine kept up with all of it. Looking back on 2016, we compiled three top 6 lists, with our best-read topics in technology, business and news.

These were 2016's six top developments in business, by popularity.

6: Circle Continues Its Move Away From Bitcoin

In a move that should not have come as a surprise, payments application Circle continued their pivot away from Bitcoin and toward more general, blockchain-based solutions in 2016. Circle CEO Jeremy Allaire even went so far as to claim that it's highly unlikelydiscussed the fintech industry more generally, blockchain technology was specifically mentioned on multiple occasions. The report found that "blockchain technology may result in a radically different competitive future in the [financial services] industry." The potential value of smart contracts was also discussed in the report.

The report identified 700 blockchain companies, 150 of which they deemed worthy of being tracked. Only 83 percent of the respondents in the survey considered themselves at least moderately familiar with blockchain technology, which led PwC to conclude that a lack of understanding of this technology may lead to market participants underestimating the impact of the blockchain on their activities.

The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

The views and


zoom in and out of the action including small cut scenes to break up the action sometimes. The commentary is quite good but still not on the level of FIFA, and the crowd sounds are fairly standard.

Pro Rugby Manager 2 takes everything that was superb about the original game and improves on it to make an even easier to play simulation. The inclusion of licenses helps the game but it would be nice to see a few more from outside Europe as well. What really helps this series is the control during matches and that is something SI could learn from, as it gives new players some interaction in the games. There may be two major Rugby games coming this year, but this is definitely going to beand striped layouts

The simplest mapping between logical and storage blocks is a contiguous block layout, which maps each logical block one-to-one to a storage block. Reading a file with a contiguous block layout is as easy as reading each storage block linearly in sequence.

In contrast, a striped block layout breaks a logical block into much smaller storage units, typically called cells, and writes repeated stripes of cells round robin across a set of storage blocks. Reading a file with a striped layout requires querying the set of storage blocks of a logical block, then reading stripes of cells from the set of storage blocks. This section discusses how EC can be supported on both block layouts.

In principle, block layout (contiguous vs. striped) and redundancy form (replication vs. EC)


behind the extensions is to allow the client node to work on multiple storage blocks in a logical block in parallel. When used together with HDFS encryption, these extensions operate on encrypted data—i.e., below the encryption layer.

On the output/write path, DFSStripedOutputStream manages a set of data streamers, one for each DataNode storing an internal storage block in the current logical block. The streamers mostly work asynchronously. A coordinator takes charge of operations on the entire logical block, including ending the current logical block, allocating a new logical block, and so forth.

On the input/read path, DFSStripedInputStream translates a requested logical byte range of data as ranges into internal storage blocks stored on DataNodes. It then issues read requests in parallel. Upon failures, it issues additional read requests for decoding.

DataNodeCPU models). We have compared the performance of these two implementations, as well as the coder from Facebook’s HDFS-RAID implementation. A (6,3) schema is used in all tests in this section.

Figure 8 first shows results from an in-memory encoding/decoding micro benchmark. The ISA-L implementation outperforms the HDFS-EC Java implementation by more than 4x, and the Facebook HDFS-RAID coder by ~20x. Based on the results, we strongly recommend the ISA-L accelerated implementation for all production deployments.

Figure 8. Encoding and decoding performance comparison

We also compared end-to-end HDFS I/O performance with these different coders against HDFS’s default scheme of three-way replication. The tests were performed on a cluster with 11 nodes (1 NameNode, 9 DataNodes, 1 client node) interconnected with 10 GigE network. Figure 9 shows the throughput results of 1)


FROM nodesource/precise-base
MAINTAINER William Blankenship <wblankenship@nodesource.com>

RUN curl https://deb.nodesource.com/node_5.x/pool/main/n/nodejs/nodejs_5.7.1-1nodesource1~precise1_amd64.deb > node.deb \
 && dpkg -i node.deb \
 && rm node.deb

RUN npm install -g pangyp\
 && ln -s $(which pangyp) $(dirname $(which pangyp))/node-gyp\
 && npm cache clear\
 && node-gyp configure || echo ""

ENV NODE_ENV production
WORKDIR /usr/src/app
CMD ["npm","start"]

RUN apt-get update \
 && apt-get upgrade -y --force-yes \
 && rm -rf /var/lib/apt/lists/*;Q:

Retrofit 2 RequestBody JsonArray

How can I put a JSONArray into a RequestBody without a runtime exception being thrown?
@Multipart
@POST("/call_method")
Call<MyResponse> callMethod(@Part("token")RequestBody token,@Part("params")RequestBody params);

I need to put JSONArray into params. What I currently do:
callMethod(RequestBody.create(MediaType.parse("text/plain"), token),
           RequestBody.create(MediaType.parse("text/plain"), jsonArrayParams));

But when I execute this method, I'll get a runtime exception:
com.google.gson.JsonSyntaxException: java.lang.IllegalStateException: Expected BEGIN_OBJECT but was BEGIN_ARRAY at line

And very intersting: The request is executed (check via CharlesProxy) but I can't see it result due to the runtime exception.
How can I fix this bug?

A:

the execution is fine, your problem is in the response,

Expected BEGIN_OBJECT but was BEGIN_ARRAY

as you declared receiving an object Call<MyResponse> while you are receiving an Array
you need to change the Type in the callback as following
Call<MyResponse[]> callMethod(@Part("token")RequestBody token,@Part("params")RequestBody


red teamers or attackers willing to compromise an Active Directory infrastructure is to be able to obtain users and computers credentials without being noticed by detection countermeasures.

For this purpose, several attack techniques have been developed through time: LSASS injection, abusing Shadow Copy, NTFS volume parsing, ESE NT operations, sensitive attribute manipulation, etc. More details are available on the impressive synthesis from ADSecurity.org.

Among all these noisy attacks, one of them is connected to the “DCShadow” attack. Introduced in 2015, the “DCSync” attack relies on the ability for the members of the Domain Admins or Domain Controllers groups to ask a domain controller (DC) for data replication (to achieve this task, the GetChangesAll right, granted by default to administrative accounts and DCs, was necessary). In fact, as described in theinside a bucket; or 2) clip-on devices that attach to the rim of the bucket.
Conventional fabric and leather tool organizers are difficult to clean if they become soiled, are subject to wear, cuts, and tears, that impact storage capacity and durability, are not well suited to prolonged exposure to moisture and climatic extremes, or to chemicals and other substances that are associated with many tasks undertaken by tradespeople, homeowners, and hobbyists, including painting, masonry, gardening, fishing, and many other activities. They are not designed for easy removal from a bucket and they do not function well independent of a bucket. They may become ungainly and difficult to carry when loaded, with tools stored in the exterior pockets dangling outward and prone to unwanted contact with walls, doorways, and


and became increasingly engaged politically, both within the party and in local politics more generally, serving for four years as a municipal councillor in Oldenburg.   For some of this time she was the deputy leader of the SPD group on the council.   However, at the height of the ructions over professional blocks for members of extremist political parties, in 1981 she resigned from the SPD and joined the German Communist Party.   This came directly after the increasingly "moderate" SPD party executive had launched its own "party operation" ("Parteiordnungsverfahren") against the "renitente Linke" (loosely "reluctant left").   She remained a Communist Party member till 1989.

The German Communist Party never gained electoral traction with West German voters, partly because of aLUTS. These agents are likely to act via different mechanisms of action, providing the rationale for combining them to treat LUTS and ED. Indeed, alfuzosin and tadalafil show an additive relaxant effect on human detrusor muscle, human prostate tissue and human corpus cavernosum in vitro. A pilot study also suggests that daily intake of alfuzosin 10 mg and sildenafil 25 mg is well tolerated and may be more effective than monotherapy to improve LUTS and ED. Further research is warranted to establish the value of this combination therapy in LUTS and ED.