Sales Never happen in Boston, but DVF was filming an episode for its reality tv series “House of DVF” so they set up the sale to have something to film. I secretly hoped I would be on camera but I kept circling the tiny store in search of the perfect pieces. Imagine: 80% sale and 50 women in one tiny store. The changing room was just one big room with women trying on different things in all corners. It was a mess, but it was also amazing.

Amidst all the cameras and DVF girls (who all looked impeccable) were shoppers like myself just trying to find the best pieces at the ridiculously low prices. After trying on half the store I had to limit my 10 beautiful finds tomonocytes between 1 and 4 hours after reperfusion; monocyte enrichment was eventually greater than neutrophil enrichment. Monocyte chemotactic activity in cardiac lymph collected in the first hour after reperfusion was wholly attributable to C5a. Transforming growth factor (TGF)-beta 1 contributed significantly to this chemotactic activity after 60 to 180 minutes, and after 180 minutes, monocyte chemotactic activity in lymph was largely dependent on monocyte chemoattractant protein (MCP)-1 acting in concert with TGF-beta 1. Beginning in the first 60 minutes after reperfusion, C5a, TGF-beta 1, and MCP-1, acting sequentially, promote infiltration of monocytes into formerly ischemic myocardium. These events may promote the healing of myocardial injury facilitated by reperfusion.


fall onto our breakfasts, but somehow it never did. A fellow actor once informed me that she used to put a needle down the middle of her cigarette so that the ash would maintain its precarious hold, and thus tantalize her guests, but I suspect this was a myth. There were many tales about Ruby, most of which were also told of other theatre landladies, so probably had no truth in them; but the story of Ruby and the Baskerville Midgets is unique to her, and I can vouch for it.

My second visit to Stage Door was on a tour of Dial M for Murder, in which I was playing Captain Lesgate. It was mid-February and our company was only the second or third into the theatre afterin patches to near white. What startled me most was that she appeared to be smaller in a way that could not be explained simply by the normal erosions of age and infirmity. Everything about her had shrunk. Sheba tottered up to her side. She too looked unkempt, and she had begun to smell.

"Where did you spring from?" asked Ruby.

I explained and she reluctantly let me in. She said: "When are the others coming?" I replied that there was no one but myself and asked which room I was in. She said I could choose and shuffled off into the kitchen.

I climbed the stairs and selected the room that smelled least of damp. It happened to be the one I had been moved to on my last visit.


the next 23.5 hours.

The comedian contestants are informed of that night’s topics only a few hours before showtime. “You’re really forced to write really quickly to make a quality show,” says Hari Kondabolu, a New York stand-up who made his second appearance on the show during the festival. “Before the first time I did it, I was hearing [from friends who had been on: buzz in, and definitely prepare. This is not just who’s the funniest. You’re writing jokes about a wide range of things, and having options is important. And if you see a moment, take it.”

“A good panelist checks off multiple boxes ... topical joke writing skills, social media and pop culture knowledge and strong improv chops,” says Bart Coleman, the show’s senior talent producer. “Theability to riff and banter with their fellow panel mates is super important. We don’t want guests feeling like they’re on Jeopardy and can only speak when they buzz in or Chris asks them a question.”

@midnight has clear roots in the British panel show model, a format that has failed to take hold in the US until now. An avowed Anglophile, Hardwick describes the show as a “game show engine about the internet through the lens of stand-up comedy with the soul of a British panel show”. Those UK shows have long been a stepping-stone for rising British comedians, and @midnight has taken on that role as well, mixing big names like “Weird Al” Yankovic and Jim Gaffigan with up-and-coming favorites like Ron Funches and Ali Wong. The


show also highlights improvisers like Heather Anne Campbell, who have few places to shine on television.

Taping four shows a week with a writing staff about half the size of most late-night shows, one of @midnight’s core strengths is its ability to adapt to different comedic styles, allowing them to use comedians of varying backgrounds. “They invite you to add your own flavour,” says Bridget Everett, a comedian and cabaret performer who won her first appearance on the show during its New York run. “They’re like, ‘Don’t be afraid to do your thing and go crazy.’ They have all different kinds of people and I think they appreciate all different kinds of comedy.”

Comedians who excel in the format can find themselves coming back frequently, an invaluable about of screenhit in the way it did. “You don’t know how people are going to react to things,” he says. “We can’t control it. With the digital culture, you can spend a month crafting what you think is the most genius video to post on YouTube and it gets 1,000 views, and then off-handedly you capture, like, a duck sneezing, and it gets 20 million views. You just don’t know.”


legs. It's
been a fun little project.

------
marquis
Really nice but for the life of me I couldn't figure out how to edit the text?
Also I loaded an URL that was an incorrect filetype by mistake and couldn't
select*all the text in the URL field to delete it. Just a small thing..

~~~
hornbaker
Thanks for the feedback!

------
Rantenki
Definitely has the potential to be popular among the lolcats crowd (or anybody
that likes computers _and_ scrapbooking). What is the revenue stream?

~~~
hornbaker
> What is the revenue stream?

None yet... I'll figure that out if enough people find it useful. Probably
along the lines of selling virtual and physical merchandise with Bumblies on
them. Physical postcards are a real possibility - I'll probably ask Brezina if
he'll do a Sincerely deal with a web app. I'd like to avoid advertising and
keep the siteThis invention relates to a lightweight, deployable turret, such as those utilized for anti-aircraft weapons mounted on the roof of a lightweight, armored vehicle.
It is known in the art to mount various types of turrets or carriages for light weapons on the roof of an armored vehicle. Access to the turret is usually obtained from the interior of the vehicle via a hatch in the vehicle roof.
British Patent 1,294,006 describes a rocket launcher attached to the upper portion of a tracked vehicle. The rocket launcher includes a deformable parallelogram linkage structure and is located such that it completely overhangs from the front of the turret. This known structure does not make provisions for counter-balancing the weight of the weapons during deployment, nor does it provide for the adjustment


around the corner.

“So what happens if you become adept at doing that and all of a sudden you mark one in the same spot and the siren goes and you’ve got to kick it to win?

“So you’re lining up with the mental application that ‘oh I haven’t kicked one of these all day and I can’t kick it around the corner, which is my favourite kick — what hope have I got of kicking it?’”

Joe Daniher. (Photo by Darrian Traynor/Getty Images) Source: Getty Images

When asked if he would help Daniher if the forward called him for advice, Dunstall said he would be happy to talk to the Bomber.

“I’d have a chat with him, yeah no problems. He would have a million people in his ear — he doesn’trisks a `reasonable man' funeral director in the New Orleans area should foresee in conducting a funeral procession, and what measures he may or should take to prevent them.
Pickett at 1259.
In our view the allegations of the complaint, when read with all inferences favorable to the pleader as we must do,[3] is sufficient to charge the appellee with subjecting the appellant to an unreasonably hazardous traffic situation by leading the funeral procession through this dangerous intersection without safeguards or warnings. An accident in this intersection was reasonably foreseeable under these circumstances. For these reasons we reverse and remand for further proceedings, but we recognize a conflict with McCorvey.
REVERSED and REMANDED.
DAUKSCH and PETERSON, JJ., concur.
NOTES
[1]  Ralph v. City of Daytona Beach, 471 So.2d 1 (Fla. 1983); Orlando Sports


working voltage converter or an external expensive inductor for a standard inductively working voltage converter obsolete.

Hence, in the embodiment of the device shown in FIG. 1, the coil 12 of a relay 10 may be used as the inductor of the device which may be configured to be at least indirectly coupled to the positive supply terminal 36 and to the two high-side switches HS1 and HS2 of the inverter 90 for supplying the two high-side switches HS1 and HS2 with a voltage higher than the voltage at the positive supply terminal 36 for achieving any predetermined duty cycle between about 0% and about 100% for the high-side switches HS1 and HS2 of the inverter 90.

Moreover, the supply of the low-side switches LS1 and LS2 in embodiments accordingan example of an electronic switch connected in parallel to the switched contacts of a relay. Once a soon drop out of the relay is signalized by a voltage induced in the coil of the relay due to the corresponding breakdown of the current through the coil of the relay, the electronic switch may be closed with the help of the energy stored in the coil of the relay even if the actual voltage supply of the relay driver breaks down. The electronic switch may be switched off, as soon as the relay has dropped out.

Hence, in certain embodiments, the function of a relay driver may be combined with the function of an inductive voltage converter. An algorithm for controlling the current through the coil of the relay


the Vboost+ supply voltage domain, wherein the term load here refers to the current consumption in the Vboost+ supply voltage domain.

In the case shown in FIG. 6, this first load is that low such that the minimal relay holding current 14 as indicated by the dashed line may suffice to allow for the voltage conversion.

As shown in a fourth section of the current characteristic in FIG. 6, the current through the coil of the relay may be increased to a second relay holding current 19 if an increased second load in the Vboost+ supply voltage domain shall be supplied with a sufficient amount of energy.

Present characteristics of a current through the coil of a relay which depend on the load in a supply voltage domain boosted by theinductor, namely the switching of the relay, and the secondary function, namely the voltage converting function, may be designed to be independent of each other. One reason for this independence between the primary function and the secondary function of the coil as an inductor is that the relay may always be designed such that the threshold of the relay operation current 17 and/or the minimal relay holding current 14 have a desired and suitable level. This may be done by choosing the mechanical, e.g., the strength of a spring biasing a movable one of the contacts of the relay, or the electrical characteristics of the relay, e.g. the number of windings of the coil of the relay, accordingly.

FIG. 7 shows a schematic circuit diagram wherein a device according


Believe in something, even if it means sacrificing everything. #JustDoIt pic.twitter.com/SRWkMIDdaO — Colin Kaepernick (@Kaepernick7) September 3, 2018

EMBED >More News Videos Former San Francisco 49ers quarterback Colin Kaepernick has been named GQ's "Citizen of the Year."

Former 49er Colin Kaepernick is back in the headlines, this time for being one of the faces for Nike's latest ad campaign.Kaepernick unveiled the ad on Twitter, which says, "Believe in something. Even if it means sacrificing everything.""Pretty powerful when I saw that," said Nike customer Marisa Smith of Oakland.The ad commemorates the 30th anniversary of Nike's "Just Do It" campaign. Kaepernick, who spearheaded a protest movement against social injustice by kneeling during the national anthem, has been out of a job for more than a year, but this latest ad marks a data-name="<%= course.title %>"
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            <%= f.submit "Buy now", class: "bg-blue hover:bg-blue-dark w-full text-white font-semibold py-3 px-4 border-2 rounded-sm border-blue-dark shadow outline-none" %>


Impact of maternal dietary n-3 and n-6 fatty acids on milk medium-chain fatty acids and the implications for neonatal liver metabolism.
Levels of n-6, n-3, and medium-chain fatty acids (MCFA) in milk are highly variable. Higher carbohydrate intakes are associated with increased mammary gland MCFA synthesis, but the role of unsaturated fatty acids for milk MCFA secretion is unclear. This study addressed whether n-6 and n-3 fatty acids, which are known to inhibit hepatic fatty acid synthesis, influence MCFA in rat and human milk and the implications of varying MCFA, n-6, and n-3 fatty acids in rat milk for metabolic regulation in the neonatal liver. Rats were fed a low-fat diet or one of six higher-fat diets, varying in 16:0, 18:1n-9, 18:2n-6, 18:3n-3, and long-chain (LC) n-3 fatty acids.this Hamiltonian are fit to any of the cluster structures. Full details of the Hamiltonian are described elsewhere [@Menon:93-2; @Ordejon:94].

As the size of the cluster grows, the number of structural isomers increases exponentially, with the result that searching the complete configuration space for the global potential energy minimum becomes a formidable task. We found that by combining the tight-binding method with the molecular dynamics simulated annealing technique we can efficiently search the cluster configuraton space and determine the ground state geometry. We used this TB-MD method in all our calculations reported here.

Figures 1-4 display the lowest energy structures obtained using this TB-MD technique for clusters in the $N$ = 11-14 atom size range. The structure displayed in Fig. 1 consists of two tetragons in the anti-prism geometry and


Anderson, S. Maruyama, and R. E. Smalley, Chem. Phys. Lett. [**176**]{}, 348 (1991).

M. F. Jarrold, J. E. Bower, and K. M. Creegan, , 3615 (1989); K. M. Creegan and M. F. Jarrold, J. Am. Chem. Soc. [**112**]{}, 3768 (1990); M. F. Jarrold, U. Ray, and K. M. Creegan, , 224 (1990); U. Ray and M. F. Jarrold, , 2631 (1991). M. F. Jarrold and J. E. Bower, , 9180 (1992).

J. C. Phillips, J. Chem. Phys. [**88**]{}, 2090 (1988).

D. A. Jelski, Z. C. Wu, and T. F. George, Chem. Phys. Lett. [**150**]{}, 447 (1988).

E. Kaxiras, Chem. Phys. Lett. [**163**]{}, 323 (1989); Phys. Rev. Lett. [**64**]{}, 551 (1990).

B. C. Bolding and H. C. Andersen, Phys. Rev. B 41, 10568 (1990).

C. H. Patterson and R. P. Messmer, Phys. Rev. B [**42**]{},(1985); J. Chem. Phys. [**84**]{}, 5672 (1986); K. Raghavachari and C. M. Rohlfing, Chem. Phys. Lett. [**143**]{}, 428 (1988); J. Chem. Phys. [**89**]{}, 2219 (1988).

D. Tomańek and M. Schlüter, , 1055 (1986); , 1208 (1987); , 2331 (1991).

M. Menon and K. R. Subbaswamy, , 12754 (1993); [Chem. Phys. Lett.]{}[**219**]{}, 219 (1994).

P. Ordejón, D. Lebedenko, and M. Menon, , 5645 (1994). We use the first set of parameters with $a =
0.08$ and $b = -1.4$ described in this paper.

W. A. Harrison, [*Electronic Structure and the Properties of Solids*]{}, (Freeman, San Francisco, 1980).

C. M. Rohlfing and K. Raghavachari, [Chem. Phys. Lett.]{}[**167**]{}, 559 (1990).

S. Liu, Z. Bačić, J. W. Moskowitz, and K. E. Schmidt, , 7166 (1994).

E. Blaisten-Barojas and D. Levesque, , 3910 (1986).

B. P. Feuston, R. K. Kalia, and P.


Vashishta, , 6222 (1987); , 6297 (1988).

J. R. Chelikowsky, J. C. Phillips, M. Kamal, and M. Strauss, Phys. Rev. Lett. [**62**]{}, 292 (1989); J. R. Chelikowsky, K. M. Glassford, and J. C. Phillips, Phys. Rev. B [**44**]{}, 1538 (1991).

U. Röthlisberger, W. Andreoni, and P. Giannozzi, , 1248 (1992).

F. Stillinger and T. A. Weber, , 5262 (1985).

[^1]: Also at the Department of Physics, New York University, New York, New York 10003-6621
So it's been a while since I've posted anything. In addition to a number of small personal obligations I've had over the past few weeks, I've also been spending a lot of time shipping out QR clocks to my customers and handling customer service requests. I've been really eager to post a final summary of the whole QR clock experiment, but I had to wait for the experiment to end first.

Now that all of my clocks are happily in the hands of their new owners, I can.

Planning

The QR clocks were never intended to be a get rich quick scheme. The theme of my blog has always been "make an educated guess, try it, and learn from your mistakes". I've been curious about things like ordering from Alibaba and


your West Norwood handyman will price a job per hour, or maybe he will offer you a price for the job in its entirety, be sure that all the materials are included, so you don't get a nasty surprise down the road. Whenever they give you a quote for the entire job, have it in black and white and get them to sign it, so that you will know precisely what you are paying. As soon as you have an acceptable quote on paper you should discuss with them about methods of payment, some will prefer cash, some prefer bank transfers, the odd one will take a credit card and some want a cheque. When you've got all of the pertinent info, you can give them the allhow well the video performs for conversions.

Having wrestled with the pros and cons of numerous so-called â€œbolt-onâ€ video players, I think EVP is the best by far for making money online.

Email Marketing Service

Look, if you are getting traffic then you HAVE to start capturing some names. Think of it as college and going home from the bar without phone numbers (loser)!

There are many out there and it all depends upon what you want to do. For simplicity, Aweber is a solid choice. IContact and Infustionsoft are also some good alternatives.

MailChimp has a free version, but I hate the name.Â Plus youâ€™ll need to upgrade to a paid plan if you want auto-responders (at least at the time of this writing) so you might as well spring for Aweber


affairs, and providing direction for the military?

If so and if her edge is significant, then it’s reasonable, and probably compelling, to argue that filling Supreme Court vacancies isn’t reason enough to vote for Trump. But if Hillary Clinton would likely be as bad or worse than Trump in the realm of national security and foreign affairs, then voting for Trump because of whom he likely would select for the judiciary seems to make sense, if his selections are likely to be materially better than Clinton’s.

Yoo and Rabkin address the question of the kinds of Justices Trump would likely select. But again, their discussion contains a big hole. It doesn’t compare Trump to Clinton.

Yoo and Rabkin argue that Trump might not keep his “vague promises” to nominate conservatives. Hecalcite prism). The maximum coupling rate is limited by the parallelism of the prism relative to the resonator surface, an effect that is more pronounced for the pump due to the shorter wavelength.

Self-locking and double resonance
=================================

The voltage tuning that is used to scan the cavity resonances for alignment purposes could be used to lock the cavity on resonance. At the pump field intensities that are required to obtain squeezing, however, any externally applied voltage amplifies the strong photo-refractive effects already present. These effects, resulting from optically-induced charge mobility [@bryan1985magnesium; @volk1994optical], lead to strong instabilities. Although detrimental to active voltage control, these effects can be useful as they enable passive locking of the nonlinear cavity. Within a particular range of pump powers, the cavity will self-lock [@SelfLocking; @Chow:05] near resonance,


prism, similar to the tuning method used in [@schunk2015interfacing]. For the ordinarily polarized sub-harmonic, the refractive index of the green calcite prism is low enough that no light will be coupled out by this prism. The presence of the green calcite within the evanescent field will, however, alter the phase of the total internal reflection so the prism can be used to control the resonant frequency of the sub-harmonic, providing faster feedback than would be possible using only temperature tuning. Figure \[fig:redphasecontrol\](a) demonstrates that the relative phase between the pump and sub-harmonic can be tuned by nearly a free-spectral range.

![\[fig:redphasecontrol\] (a) The relative frequency separation between the pump and sub-harmonic resonances as a function of the piezo tuning voltage for the green calcite prism. (b) The linewidths for the          background: settings.background,
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UK

Mr Drakeford's statement to assembly members confirmed that a new law replacing EU farming subsidies will not be introduced to AMs until after the assembly election.

Rural affairs minister Lesley Griffiths said in September last year that she hoped to bring the bill forward before the end of the assembly term.

Initially the Welsh Government had hoped to phase in its plans, including a new funding scheme to replace EU farm subsidies, from 2021 but said last week that the ongoing Brexit uncertainty had held them up.

A second consultation on revised proposals is under way, with another promised for the autumn.

Farmers in Wales would be offered money to carry out work which protects and enhances the environment, under the post-Brexit proposals.

The Welsh Government insisted it was not a delay toconfined to the molecule, but may, in principle, contain arbitrary parts of the metallic electrode. The inclusion of part of the leads in the [*ab initio*]{} calculation was shown to improve the description of the molecule-leads coupling [@Ventra00], in particular regarding charge transfer between the molecule and the electrodes. The Fermi energy of the overall system is determined by the charge neutrality condition of the central cluster.

![\[setup\] Scheme of the single-molecule contacts analyzed in this work. The two organic molecules attached to gold electrodes, which were experimentally investigated in Ref. [@Reichert01], are referred to as: (a) “symmetric molecule", and (b) “asymmetric molecule". ](fig1.eps){width="\columnwidth"}

In order to obtain the current for a constant bias voltage, $V$, between the leads, we make use of non-equilibrium Green function techniques. Since the Hamiltonian of Eq. (1)


the down-stream response of the cells \[[@R11]--[@R16]\].

The term endocytosis describes two different cellular uptake mechanisms: pinocytosis, which involves the uptake of fluids and molecules within small vesicles and phagocytosis, which is responsible for engulfing large particles (e.g., microorganisms and cell debris). Pinocytosis covers macropinocytosis, clathrin-mediated endocytosis, caveolin-mediated endocytosis and clathrin- and caveolin-independent endocytosis \[[@R8],[@R17]--[@R20]\]. However, not all cell types are equipped with the required machinery to perform the entire spectrum of endocytotic pathways. Therefore, these pathways are specific to types of cells and subsequently determine the trafficking and intracellular fate of particles \[[@R21]\]. Red blood cells are a common example, as they do not have any phagocytic receptors on their surface and no actin--myosin system, therefore they serve as a model for non-phagocytic cells to study how NPspenetrate through cell membranes \[[@R22]\].

Phagocytosis and macropinocytosis are both dependent on actin \[[@R15],[@R23]\]. Phagocytosis is carried out by professional phagocytes (i.e., monocytes/macrophages, neutrophils and dendritic cells), which in turn form intracellular phagosomes. Macromolecule and particle uptake is triggered via the interaction of the responsible receptors on the cell surface and the ligands. Macropinocytosis, which is also actin-driven, forms protrusions at the outer cell membrane which then again fuse with the cell membrane by taking up larger fragments or debris \[[@R14]\].

Clathrin-mediated endocytosis is very well studied and is, like most pinocytotic pathways, a form of receptor-mediated endocytosis. This abundant pathway is essential for the uptake of many molecules such as low-density lipoprotein and transferrin \[[@R24]--[@R25]\]. When clathrin-mediated endocytosis is initiated, the so-called "coated pits" come into play consisting of


transmembrane receptors and cytosolic proteins, such as clathrin and the AP2 adaptor complex \[[@R20]\].

On the other hand, caveolin-mediated endocytosis is responsible for the homeostasis of cholesterol \[[@R20]\]. The static structures of caveolae form flask-shaped invaginations in the cell membrane. Many cell types such as the capillary endothelium, type I epithelial cells, muscle cells as well as fibroblasts, exhibit caveolin-mediated endocytosis, which occurs at the site of the lipid rafts \[[@R20],[@R26]\]. These rafts are plasma membrane regions (subdomains), which consist of glycosphingolipids and high amounts of cholesterol \[[@R27]\]. The protein which gives shape and structure in caveolin-mediated endocytosis is caveolin-1, a dimeric protein which binds cholesterol onto the cellular surface for uptake and intracellular trafficking (lipid homeostasis) \[[@R28]\]. Also located at the site of lipid rafts is flotillin-1, anfluorescently labelled transferrin can be used to investigate clathrin-mediated endocytosis \[[@R32],[@R41]--[@R42]\].

Caveolae and lipid raft internalizations are known to be inhibited by nystatin, filipin and methyl-β-cyclodextrin (mβcd) through depletion of the cholesterol from the cell membrane by forming inclusion complexes with cholesterol \[[@R31],[@R43]\]. It was also shown that mβcd inhibits clathrin-mediated endocytosis, since clathrin uptake requires cholesterol as well \[[@R11],[@R44]\]. All of these mentioned inhibitors form aggregates which accumulate cholesterol and separate it from the membrane structures. Finally, the cholera toxin subunit b (ctx-b) \[[@R45]\] has been shown to enter the cells by caveolin-mediated endocytosis, therefore this protein can be used to control the inhibitors in any experimental setting.

To show that the endocytotic uptake route of choice is dependent upon the particle size, we deployed two fluorescently labelled polystyrene


red. Scale bar: 8 µm.](Beilstein_J_Nanotechnol-05-1625-g003){#F2}

Endocytotic inhibitors
----------------------

With the knowledge of the presence of specific uptake proteins, it is now feasible to elaborate on the different uptake routes in each cell type by applying different chemical inhibitors. Inhibitors of clathrin- and caveolin-mediated endocytosis or macropinocytosis and phagocytosis were tested for their optimal concentration, exposure time and cell impairment in both cell types ([Table 1](#T1){ref-type="table"} and [Fig. 3](#F3){ref-type="fig"}). The cell morphology was assessed by LSM ([Fig. 3](#F3){ref-type="fig"}) and the cytotoxicity by lactate dehydrogenase (LDH) assay (see Figure S1, [Supporting Information File 1](#SD1){ref-type="supplementary-material"}). Trypan blue staining marked the integrity of the cell membrane for cells which were impaired by the inhibitor (red insets, [Fig. 3](#F3){ref-type="fig"}) and revealed the following percentage of dead cells for J774A.1 cells (*n* = 3): negative control 20%µm particles in J774A.1 cells. The negative controls have a scale bar of 10 µm.](Beilstein_J_Nanotechnol-05-1625-g006){#F5}

Particle uptake evaluation
--------------------------

After 1 hour of incubation, intracellular particles and NP events (either agglomerates or single NPs, which cannot be distinguished by LSM) were visualized in both J774A.1 and A549 cells ([Fig. 5](#F5){ref-type="fig"} and Figures S2 and S3, [Supporting Information File 1](#SD1){ref-type="supplementary-material"}). In control cells that were not treated with any inhibitors, uptake of NPs was observed within only a few minutes in both cell types ([Fig. 5](#F5){ref-type="fig"}). These observations are supported by live cell imaging, which revealed that NP uptake is a very fast process, starting 5 to 10 minutes after exposure to the cells (Figures S2 and S3, [Supporting Information File 1](#SD1){ref-type="supplementary-material"}). Uptake of 1 µm particles was only observed in J774A.1


with this cell type. In addition, caveolin-1 was not detected. Therefore, the role of this uptake mechanism is still not clear in this cell and for this particle type. It also has been shown that caveolin-1 was only rarely present in human macrophages \[[@R62]\]. Consequently, one can conclude that NPs are taken up by a different mechanism in this cell type, which might also depend on the agglomeration behavior of particles on the cell surface, and thus the "secondary" size of the particles. Neither chlorpromazine nor mβcd (i.e., blocking the clathrin-mediated and the caveolin-mediated pathway) could fully inhibit the uptake of 40 nm NPs in A549 cells, since intracellular particle events could still be detected after treatment with those two inhibitors. Thus, A549 may also employ multiple endocytoticran over a time period of 60 minutes during which the cells were kept in a constant environmental at 37 °C and 5% CO~2~. Image acquisition was performed as described above.

Lactate dehydrogenase (LDH) assay
---------------------------------

A 1 mL sample of the supernatant of each experiment was collected and stored at 4 °C to determine cytotoxicity. Triton X (0.2% in unsupplemented RPMI) was used for cell lysis as a positive control. The supernatant of untreated cells was used as negative control. The LDH assay was performed with the Cytotoxicity Detection Kit (Roche Applied Science, Mannheim, Germany) according to the supplier\'s manual. Each supernatant was measured in triplicate. All measurements were analyzed as *n* = 3 experiments.

Trypan blue exclusion assay
---------------------------

The assay was carried out according to the manufacturer's manual (Sigma-Aldrich, Steinheim, Germany).


Pigmented malignant hidroacanthoma simplex mimicking irritated seborrheic keratosis.
Pigmented variant of malignant hidroacanthoma simplex (PMHS) is very rare. We are aware of only two reported cases, all arising in pigmented hidroacanthoma simplex (HS). We report the third case of PMHS arising in a pigmented HS. A 71-year-old-woman presented with a well-demarcated pigmented hyperkeratotic tumor on the right knee resembling irritated seborrheic keratosis. Histopathologic examination of the excised tumor revealed intraepidermal proliferation of atypical polygonal poroid cells forming large, sharply demarcated nests with colonization of dendritic melanocytes. In addition, there were focal changes of a benign pigmented HS and syringofibroadenoma. The key diagnostic features of ductal structures and intracytoplasmic lumina were highlighted by carcinoembryonic antigen and epithelial membrane antigen immunostaining. PMHS should be differentiated from irritated seborrheic keratosis, melanoacanthoma, Bowen'sBackground {#Sec1}
==========

Heart failure (HF) is a major cause of hospitalization and mortality worldwide \[[@CR1]\]. Increased hemodynamic load is one of the major contributors to the development of HF. Cardiac hypertrophy is considered to be an adaptive response to pressure or volume overload, which is characterized by the enlargement of heart muscle. Although the initial phase is beneficial in maintaining cardiac function, prolonged hypertrophy will lead to deleterious consequences and eventually HF. Nowadays, many medicines, such as β-adrenergic receptor blockers, angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers and diuretics, have been universally used to treat cardiac hypertrophy and HF. These medicines can be effective to partially relieve the symptoms of HF, but cannot reverse the progression of HF. In fact, mortality rates of HF still approach about 20% per year \[[@CR1]\].


defined as the contents of inorganic phosphorus (μmol) per mg total protein and hour.

Statistical analysis {#Sec9}
--------------------

All statistical analyses were performed using the SPSS Statistical software (version 17.0). Values are expressed as mean ± standard error (SEM). One-way analysis of variance was used to analyze the differences between the means of groups, followed by Tukey post hoc test. A value of *P* \<0.05 was considered significant.

Results {#Sec10}
=======

Establishment of hypertrophic model {#Sec11}
-----------------------------------

Cardiac structure and function in rats were assessed by echocardiography at 4 weeks postsurgery (Additional file [1](#MOESM1){ref-type="media"}A). The parameters of LV wall thickness including IVSs, IVSd, LVPWs and LVPWd were significantly increased in aortic banded rats compared with sham rats (Additional file [1](#MOESM1){ref-type="media"}B). On the contrary, LVIDs was significantly decreased in aortic banded rats compared with sham rats, whereas no significant differencein LVIDd was detected between the two groups (Additional file [1](#MOESM1){ref-type="media"}C). Moreover, the parameters of systolic function (EF and FS) were significantly increased in banded rats compared to sham rats (Additional file [1](#MOESM1){ref-type="media"}D). These data indicated that the rat model of compensatory cardiac hypertrophy induced by aortic banding was successfully established.

Antihypertrophic effect of resveratrol {#Sec12}
--------------------------------------

Histological analysis showed that surface areas and diameters of cardiomyocytes were remarkably increased at 8, 10 and 12 weeks postsurgery in aortic banded rats compared with sham rats, but decreased by 27%, 14% at 8 weeks and 46%, 26% at 10 weeks postsurgery respectively in resveratrol-treated rats compared to banded rats. However, we found that resveratrol treatment failed to reverse enlargement in cardiomyocytes at 12 weeks postsurgery (Figure [1](#Fig1){ref-type="fig"}A-C).Figure 1**Effects of resveratrol on the size of cardiomyocytes (n = 3) and


with long-standing untreated PO, LV systolic performance decreased and LV dilatation occurred, which are the key features of decompensatory phase, namely HF. Resveratrol treatment effectively preserved cardiac systolic function and LV chamber dimension. Previous studies demonstrated that resveratrol improved contractile function with abolishing cardiac hypertrophy caused by PO \[[@CR1],[@CR3]\]. Interestingly, we found that resveratrol continuously exerted cardioprotective effects in banded rats and these effects sustained to decompensatory stage of HF even though its antihypertrophic effect was absent. Similarly, Ste'phanie Rimbaud found that resveratrol treatment exerted beneficial protective effects on survival and cardiac contraction in DSS rats fed with HS-NT which is a hypertensive model of HF \[[@CR5]\]. However, the mechanism underlying the development of HF in DSS rats is apparently different from aortic banded rats.

Cardioprotective mechanisms of resveratrolonly partially prevented mitochondrial lesions. However, other studies demonstrated that resveratrol significantly attenuated the abnormality of mitochondrial ultrastructure in sepsis-induced myocardial depression with a large dose (30 mg/kg or 60 mg/kg) \[[@CR21]\], and preserved mitochondrial function and biogenesis contributing to improve cardiac energy metabolism and reduce oxidative stress in other models \[[@CR5],[@CR20],[@CR22],[@CR23]\]. This difference could be explained by the diversity of resveratrol dosage, the period of treatment, the stage of HF and animal models.

Ca^2+^ cycling which refers to the release and reuptake of intracellular Ca^2+^ is highly regulated in cardiomyocytes and determines the process of cardiac muscle contraction and relaxation. Defects in the regulation of Ca^2+^ handling proteins contribute to HF. To our knowledge, the effects of resveratrol on Ca^2+^ handling proteins in HF remain unclear. Impaired SERCA~2~ function and


\[[@CR26]\].

A prevailing theory is that one of the major mechanisms proposed to underlie resveratrol mediated cardioprotection is reduction of oxidative stress \[[@CR4],[@CR27],[@CR28]\]. Polydatin, a resveratrol glucoside, has been shown to prevent enhanced Ca^2+^ spark-mediated SR leak by reducing oxidative stress in RyR~2~ in burn-traumatized heart, leading to protection of cardiac function against burn injury \[[@CR29]\]. Further studies are needed to understand whether reduction of oxidative stress by resveratrol could regulate RyR~2~ and other Ca^2+^ handling proteins in aortic banded rats.

Conclusions {#Sec22}
===========

These data demonstrated that resveratrol treatment prevented cardiac hypertrophy induced by PO with time-limitation and inhibited the development of HF via improving cardiac structure and function. The novel findings on mechanisms underlying cardioprotection of resveratrol include protection of myocardium ultrastructure and regulation of global Ca^2+^ handling proteins.

Additional filesmade them like biscuits and beat and egg white and 4 tablespoons of butter together and brushed them on top. They came out awesome I will definatly be making these again.

Most Helpful Critical Review

Apr 11, 2003

The fact that these are called "rolls" is misleading. They are in fact biscuits. The flavor was okay but they were not nice enough to serve with our Easter dinner. We ended up making something different.

My husband loved these. No-they aren't a true yeast roll, but we found them to be lighter than a biscuit too. I did allow the rolls to sit in a warm spot for about an hour before baking, and they rose a little. Maybe that's what made them so fluffy. Skipped the butter inside, but did brush them


standing in one place to let him kick them. Front-leg side kicks are used in kick-boxing, and a bit less often in MMA, but the most common use is as a way of keeping distance, pushing the advancing opponent away, and often with the chambered kick acting as a threat, forcing the opponent to break their rhythm as they anticipate the incoming kick, and allowing the kicker to change the direction more readily when an opponent side-steps.
If you wanted to land this kick in the ring, I suspect that you will have to:

Chamber it the same as a front teep, with the knee up, only twisting into the side kick as you kick
Be able to transition into another technique and/or re-target your kick if your opponent moves
Practice otherwas initially presented to the government. However, Blecker also recognized that a false claim may be "presented" in more than one district. The court held that venue was proper in both the district where false claims were presented to an intermediary, and the district where the intermediary presented the claims to the government. Id. at 633.
Similarly, this circuit in United States v. Ebersole, held that venue was proper for false claims in the Eastern District of Virginia, as one of several districts "through which force propelled by [defendant] operated" as the claims proceeded through the necessary channels on their way to producing funds. 411 F.3d 517, 533 (4th Cir. 2005). In Ebersole, the false claims in the form of an invoice were initially presented to the Federal Emergency


can adequately prepare a defense without being surprised. Accordingly, Counts One and Two of the superseding indictment properly state offenses and invoke this Court's jurisdiction. Defendant's Motion to Dismiss Counts One and Two is hereby DENIED.

Motion for a Bill of Particulars
In addition to the Motion to Dismiss Counts One and Two, Defendant filed Motion for a Bill of Particulars pursuant to Fed.R.Crim.P. 7(f). Specifically, Count Three of the indictment charges Defendant with mail fraud, alleging that from "November 2004 and continuing to in or about December 2004," Defendant committed mail fraud by delivering fraudulent documents relating to a 2004 Yukon Denali through DHL Express Delivery Service.
The purpose of a bill of particulars "is to fairly apprise the defendant of the charges against him so that he may adequately$\ell^{2rs} \operatorname{disc}(M)$, and thus has $\ell$-adic valuation as most $2rs+v_0=C'+v_0$. The lemma also shows that $\operatorname{disc}(N)$ divides $\operatorname{disc}(M_1)$, which proves (2).

Let $X$ be a K3 surface over $k$. For a prime number $\ell \ne p$ put $$M_{\ell}(X)={\operatorname{H}_{{\operatorname{\acute{e}t}}}}^2(X_{\ol{k}}, {{\mathbf Z}}_{\ell}), \qquad N_{\ell}(X)=M_{\ell}(X)^{\phi=q}.$$ Then $M_{\ell}(X)$ is a free ${{\mathbf Z}}_{\ell}$-module of rank 22, and the cup product gives it the structure of a unimodular lattice. The space $M_{\ell}(X)$ admits a natural ${{\mathbf Z}}_{\ell}$-linear automorphism $\phi$, the geometric Frobenius element of ${\operatorname{Gal}}(\ol{k}/k)$. The map $\phi$ does not quite preserve the form, but satisfies $(\phi x, \phi y)=q^2 (x, y)$. It is known [@D] that the action of $\phi$ on $M_{\ell}(X)$ is semi-simple. We give $N_{\ell}(X)$ the structure of a lattice by restricting the form from $M_{\ell}(X)$.

\[step1a\] There exist constants $C_1=C_1(k)$ and


We choose a Henselian discrete valuation ring $R$ with algebraically closed residue field dominating $M$ and centered at $m$ and pull the family back to $R$. This results in a triple $(\mc X_R,\widetilde v_R,\widetilde\alpha_R)$ with closed fiber $(X,v,\alpha)$ (up to algebraically closed base field extension) and geometric generic fiber having Picard number $1$ and characteristic $0$, on which $v$ remains primitive. Write $H$ for the relative polarization from $\ms L$ and $v$ for $\widetilde v_R$.

Consider the relative moduli space $\ms M(v)\to{\operatorname{Spec}}R$ parametrizing $H$-stable $\ms X$-twisted sheaves with Mukai vector $v$. Since any simple twisted sheaf with unobstructed determinant is unobstructed, we know that $\ms M(v)$ is a ${\boldsymbol{\mu}}_{\ell^n}$-gerbe over a smooth algebraic space $\mc M\to{\operatorname{Spec}}R$. By Theorem 3.16 of [@Y], the geometric generic fiber of $\mc M$ overExclusive: Google App Engine ported to Amazon's EC2 — One of the biggest criticisms of Google's App Engine have been cries of lock-in, that the applications developed for the platform won't be portable to any other service. This weekend, Chris Anderson, the Portland-based cofounder …

Is Google App Engine a Lock-in Play? — Venture capitalist Brad Feld just put up an intriguing post comparing Google App Engine to Amazon EC2. The meat of the entry is from an analysis by Brad's friend Scott Moody. Here are the juiciest bits, pro and con: … This last point is really very serious.

Company claims to sell Mac clone for $399 — Source: Psytar (at least until Apple Legal has their morning coffee) — Personal technology enthusiasts yearning for the Mac Experience without


Q:

confusion on UIView, its class and UIViewController - xcode iOS objective-c

In storyboard, I dragged out UIView onto my ViewController.
Assign UIView to custom class "myUIView" (which will be myUIView.h and myUIView.m)
Set up ViewController like this:

ViewController.h
#import <UIKit/UIKit.h>

@interface ScheduleViewingVC : UIViewController

//for the dragged-out UIView
@property (strong, nonatomic) IBOutlet UIView *myUIViewOutlet;

//to do some drawings on myUIViewOutlet
@property (strong, nonatomic) myUIView *myUIViewClass;

@end

ViewController.m
#import "ViewController.h"

@implementation ViewController
- (void)viewDidLoad {
    [super viewDidLoad];

    //resize my UIView into a square
    CGRect screenRect = [[UIScreen mainScreen] bounds];
    CGFloat screenWidth = screenRect.size.width;
    CGRect squareFrame = CGRectMake(0, 0, screenWidth, screenWidth);
    _myUIViewOutlet = [[UIView alloc] initWithFrame:squareFrame];
}
@end

If I run this project,
- (void)drawRect:(CGRect)rect {}

inside myUIViewClass.m runs automatically since.. it's linked to myUIViewOutlet.
Now, I need sendthe anisotropic rare earth hard magnetic materials, such as Sm—Co magnetic powder or anisotropic NdFeB magnetic powder prepared by HDDR (Hydrogenation, Disproportionation, Desorption, Recombination) process, the term of anisotropy here is only denoted as magnetocrystalline anisotropy. The powders can be oriented when applying a magnetic field. The powders can be used to produce anisotropic compressing or injection magnets with a magnetic field. However, the powders don't present a calender anisotropy. As an example of Sm—Co powder, because it doesn't have calendar anisotropy, the calendar magnets based on Sm—Co powder are isotropic, and its maximum energy product is low, thus having no significance for commercial applications.
Around 1990, J. M. D. Coey et al. disclosed a material having a molecular formula of Sm2Fe17Nδ (J. M. D. Coey et al., “Rare


Earth based magnetic materials, production process and use”. European patent Application number: 91303442.7); Iriyama Kyohiko et al. disclosed a similar material based on rare earth, iron, nitrogen and hydrogen (CN 89101552.3); Yingchang Yang et al. made a neutron diffraction study to determine the crystallographic structure of the compounds R2Fe17Nx, indicating the nitride compounds are crystallized in the Th2Zn17-type structure, and nitrogen atoms occupy a specified interstitial site (Yingchang Yang et al. (1991) Neutron diffraction study of ternary nitrides of R2Fe17Nx, Journal of Applied Physics, 70(10): 6018). Due to the interstitial atom effect, the above nitride compound presents a high Curie temperature Tc, a large saturation magnetization Ms, and a strong magnetocrystalline anisotropic field Ha. As a result it is considered as a good candidate for developing a hard+ goodRect!.width
        } else {
            badX = 0.0
        }

        badRect = NSRect(x: badX, y: 0, width: r.width * CGFloat(badPercent), height: barHeight)
        let badPath = NSBezierPath(roundedRect:  badRect!, xRadius: 6, yRadius: 6)
        RatingDistributionView.badColor.setFill()
        badPath.fill()
    }

    //Draw dividers
    let divWidth = CGFloat(6.75)

    if self.goodPercent != 0.0 && (self.okPercent != 0.0 || self.badPercent != 0.0) {
        let divX =


okay?" "Why hasn't she acknowledged my dinner offer?" "Something's wrong!" "She's not responding to my poking stick." "Poke harder, damn it!" "I'm poking as hard as I can!" "I'm sorry, Fry, but I'm afraid Leela is in an irreversible coma." "Coma, coma, coma, coma, coma chameleon" "My soul mate is gone." "Why should I go on living?" "Because the pain slowly fades, but the love is forever." "Yow!" "But what if I forget the sweet sound of her voice, or the moist touch of her eyeball on my lips?" "Are you still hung up on what's-her-name?" "Move on already!" " Maybe you're right." " Maybe I'm always right." ""Build-a-Bot Workshop."" "It's time to start living again." "At least it's something to distract me from Leela." "Nah." "Now, thatback to the thing you
said at the beginning, which is
that people are kind of out of
work, and a lot of people are
really, really suffering. That
is absolutely true, and the
level of suffering that working
people will be facing not just
now, but probably over the
course of the next two years,
unemployment is likely to stay
very high. In many countries,
over the course of the next
couple of years... It's going to
be huge. Unseen since probably
the '70s and '80s. And then you
compare that with the fact that
in many states in the Global
South, governments are being
forced to choose between
servicing
debt to creditors, and
if they fail, being forced to
default and shut out of global
capital markets, or


into the position where you
have
governments that are relatively
sympathetic to socialist
movements, saying: At the very
least, the apparatus of the
state should not be used to kill
or imprison these people. And
then you can start thinking
about building up those
movements at the level of the
firm, on the street, whatever,
and you have much more space to
do that. Of course, the
anti-union legislation that's
used across the US and UK and
many parts of the world is
another element of that. So long
story short: Can we achieve any
modicum of kind of improvement
in our
science of living just by the
demands of the state? No. Can we
achieve our ends without
focuses on ing on the state? I
don't think so.
BRIAN: Okay. Let me throw aQ:

Which is better practice: complex SQL statements or Recordset manipulation in Access VBA?

I'm doing some VBA development and I found creating SQLs quite efficient way of getting everything done (selecting and updating).
But I got to this stage where my SQL statements contain complex Switches and WHERE conditions where I have another Selects to update appropriate records. Therefore, I create this SQLs and I simply run it via "CurrentDb.Execute strSQL" and it does everything fine.
The question is, why would I declare ADODB.connections etc, set recordsets, loop through it and manipulate the data one by one?

A:

why would I declare ADODB.connections etc, set recordsets, loop through it and manipulate the data one by one?

No reason. If you can do it in plain SQL you can stick with it.
But in MS


off by her office.

Quoted in a Herald Live report, Motshekga stated that, in her right mind, she would have never greenlighted a campaign that objectifies women in a country still struggling to get a foothold of gender-based violence.

“As Minister of Basic Education, I didn’t authorise nor was informed of such a campaign involving semi-naked women. Even if I was informed, I wouldn’t have given any permission purely based on the principle that women aren’t objects. The objectification of women is an affront in our battle against the pervasive nature of patriarchy and the scourge of gender-based violence,” she scathingly said.

The Basic Education Minister noted that the objectification of women has no place in our society and those responsible for putting her ministry into disrepute will be dealt withup and it's 13 years later. The hard part is accepting the fact that maybe you're not as important as you think you are and you should probably just get on with it." [via PRP]

Tool will embark on a North American tour with support from Killing Joke starting Oct. 13 in Sacramento, Calif. and concluding Nov. 25 in Washington D.C. For tickets to the upcoming shows, click here.


and yes, even rage. How can we physically embody a “holy nation” when we may be nurturing evil in secret?

Jesus acknowledges this in Matthew 5 with a scathing lecture. In a series of six statements, beginning with “You have learned, but what I tell you,” Jesus summarizes the Ten Commandments and takes them from a list of elementary school rules to Master’s level psychology report. He tells the listening crowd that the true meaning of the Law is a much more radical look at love than it is an adherence to certain actions. It is not enough just to keep one’s emotions in check. Instead, one must look inside oneself, objectively appraise whatever morally destructive force is there, and then eradicate it. Only then can we attempt anShe took a shaky breath. She wasn’t sure if she was scared, excited or both. A part of her wanted to run. But a bigger part of her wanted to scream, cry and laugh all at the same time. She felt her heart pull. Time and time again, she had been feeling as though she was in a dream. But, every time she looked at it…it smacked her in the face. Threading her fingers, she gripped tightly. It was real. This was real.

“Me neither.” She pulled away from him and slowly entered the water, the element teasing her. He watched intensely as she slowly but surely grew a bit deeper, fingers creating circles around her.

“Roto..”

“Yeah babe?”

“Come join me…” She turned to look at him and all feeling in


you are Son.” He pat him on the back and for a moment he remained still. But soon he turned on his heel and went to his room to get prepared. As he wrapped the hakama straps around his waist, his palms grew sweaty.

“Hiroto-sama, I just want to keep you aware of the time-”

“In about a half an hour right?” He interjected.

“Yeah.”

“Understood.” The man at the door smiled.

“You’re so nervous your Kansai-ben is coming out. You’ll be just fine.”

“Hm.” The man slowly closed the door and he turned back to his reflection. He pulled the straps apart gently until the fabric wafted to the ground. Slipping into something comfortable, he ran fingers through his hair for what seemed the thousandth time. The nervousness sat right in the pitthe door. Straightening up, she sniffed and pat her cheeks.

“Kay enough cryin. I got a wonderful man out there who wants to make me his wife. I can’t be cryin over the past.”

“That’s right.” Mina came to her and rubbed her shoulders.

“You are a most fitting bride Rae.” Tucking some loose strands of hair out of her face, Mina pressed a kiss to her forehead.

“Are you ready?” She took a deep breath, hands starting to shake again. This time she held them steady and gave her a smile.

“I’m ready.” She grabbed a small bouquet and started to walk down the hall. Patrons peeked their heads out of the shoji, whispering, talking, wondering. Up ahead she heard a commotion bringing her to a stop.

“Hiroto we have to go this


her hand, only the wood between them separating them.

“Prayer.” She felt her eyes grow misty but she squeezed his hand back.

“You’re right.”

“Let’s do this properly from the beginning.” She took a deep breath and closed her eyes, pushing out all of the watching curious eyes and chattering. Only the feel of his hand secured her.

“Dear God in Heaven, we thank you for this moment. Bringing us together in unity for a time such as this. I pray before we take our vows before your presence that you bless our union. Let our marriage be a prosperous one, a unity that is fruitful and blessed. May you pour out your blessings upon us as we become one to do your will on earth. Thank you for giving me thishe pushed off of the wood.

“See you soon?” She swallowed, face warm.

“See you soon.”

***

The waves crashed against the shore and the sun was shining bright, clouds puffy and white. Off in the distance, the cry of the birds carried on the wind. She felt the wind rustle the flowers interwoven in her hair and tilt her head back, letting it whisper across her skin. All was still.

“I apologize. I didn’t mean to.” Her cheeks grew even more rouge and she bit her lip. Gentle fingers lifted her chin.

“I want you to know that you have made me a very happy father-in-law. You are everything I could ask for and I’m so thankful I finally received the daughter I wanted.If you would allow me to…I’d like to present you


I see a hell of a lot of sake being consumed tonight.” Roto chuckled.

“You actually did it.” He grew still as a voice spoke behind him. Turning slightly, he saw his cousin Takamasa standing there with a smirk.

“So you’re here.”

Why wouldn’t I be?”

I thought perhaps you had something more important to do.” The smirk slid off of Taka’s face.

“In the affairs of the Iwase, I always show up.”

“Ah,”

“I never thought you would have actually marry her.”

‘Is that so?”

“I thought she was just your latest fling.”

“Guessed wrong.” Taka snort.

“It seems I did.”

“Are you congratulating me…I’m not sure.”

“Yes of course. You have a beautiful wife and now you can finally start to uphold your duty as Head of the family.”

“Finally?” He eyed him intently, irritation sparking.

“I figured you two wouldbe out here.” Both men turned as Tomoya slowly approached them, a deep boyish grin on his face.

“So you’re here too.”

“That I am.”

“It’s a pity you aren’t married yet Tomoya.” Taka mused dryly, a light grin on his face.

“One day.”

“The cat seemed to drag us all here together again… I don’t know why.”

"To celebrate of course.”

“I suppose.”

“Taka, don’t be mad that Hiro finally got married and you’re still single.” Taka snort again, this time louder.

“Please.”

“So… you guys out here havin a mature talk or can we get back to the booze?”

“Frankly, I’m not sure what we’re doing.” He answered with a withdrawn sigh.

“How long has it been since you’ve waited for this?” Taka asked, leaning back against the shoji.

“A few years. At last, this man took care of


practicable to the left curb or edge of the roadway. Source: Tex. Transp. Code Ann. §551.103

If you have any questions about these laws or how they may apply, please feel free to contact us via email ([email protected]) or phone (1-844-531-7530) to discuss this topic further.there is a sequence-out-of-range packet in the resequenced packets received over a downstream channel with a downstream channel ID (“DCID”) indicated by the channel ID TLV 441a. If the fourth bit is 0, the CM does not transmit the CM-STATUS message even if there is the sequence-out-of-range packet.
The CM-STATUS event control TLV 460 includes sub TLVs, such as an event type code TLV 461 of type=11.1, a maximum event hold-off timer TLV 462 of type=11.2, and a maximum number of reports-per-event TLV 463 of type=11.3.
In an exemplary embodiment, the DOCSIS 3.0 standard defines that the event type code value of the sequence-out-of-range event is 3. When the event type code TLV 461 value in the MDD message is 3 and a sequence-out-of-range event occurs, the CM is required


on the CM. The CM-STATUS event type state machine is a kind of finite state machine (FSM) for determining, based on event-based state transition of the CM, whether the CM transmits a CM-STATUS message including resequenced packet status information.
Referring to FIG. 7, the CM operates the CM-STATUS event type state machine consisting of an IDLE 705 state and a SENDING 725 state for respective events allowing for transmission of the CM-STATUS message via an MDD message or a CM-CTRL-REQ message.
In the IDLE state 705, the CM has the transaction ID (TID) value of zero. When a state transitions from the IDLE state to an “on” state due to occurrence of an event of a specific type (710), the CM sets a ReportsLeft variable to a maximum number ofwas headed in the wrong direction… (ever been that sure of something?)

UNDERSTAND – Nicodemus thought it was just going to be another typical holiday season, get everything ready, make all the necessary preparations (choose the lamb, bake the bread, cook the bitter herbs) THEN - celebrate the Passover… (You know the annual reminder that God’s people had been observing on the 14th day of the first month for over 1400 years).

A CELEBRATION – where Israel remembered the time that God delivered them from 400 years of bondage in Egypt, BRINGING - the mighty Pharaoh to his knees with 10 plagues… THE – last one (the death of all the firstborn in the land) ‘passed over’ God’s people because they had applied the blood of a lamb to their


Parti Kebangsaan Melayu Malaya

Parti Kebangsaan Melayu Malaya (PKMM), also known as the Malay Nationalist Party, was founded on 17 October 1945  in Ipoh, Perak. The party was the first Malay political party formed after the Japanese occupation of Malaya.

The main goal of the PKMM was to achieve full independence for Malaya and to oppose any form of British colonial rule. The five principles adopted by the PKMM were a belief in God, nationalism, sovereignty of the people, universal brotherhood and social justice. These principles mirrored the Pancasila of Indonesian nationalism and many of the PKMM activists were influenced by nationalist developments in Indonesia and sought for the unification of Indonesian and Malay nationalist struggles in an Indonesia Raya.

In response to British proposals for a Federation of Malaya,       users u ON u.uID = s.user_id
    ORDER BY
        s.score DESC
        , s.created_at DESC
    LIMIT 15

If two or more rows have the same score, I want the latest one (or earliest - I don't care) to be ranked higher. I tried modifying the subquery with AND id > s.id but that ended up giving me an unexpected result set and different ties.

A:

Select S.score, S.created_at, U.name
   , U.location, U.icon_id, U.photo
   , (Select Count(*) + 1
        From scores S2
        Where S2.score > S.score


    scanf("%f", &matrice[i][j]);
            }

            // pivot initial coords

            lpiv = 1;
            cpiv = 1;

            printf("\n----- Entered Matrix -----\n\n");
            afisare_matrice(dimensiune, matrice, 0);
            printf("\n");

            for(int pas = 1; pas <= dimensiune - 1; pas++) {

    printf("----- Step %d -----\n\n", pas);
                afisare_matrice(dimensiune, matrice, lpiv);
                printf("\nResult after step %d : %4.2f\n\n", pas, rezultat);
                lpiv++;
                cpiv++;
            }

            // final result

            rezultat = rezultat * matrice[dimensiune][dimensiune];


      if tok_acc:
            yield " ".join(tok_acc)

def clean_lines(txt, min_char_ratio=0.9, min_length=50):
    txt = ftfy.fix_text(txt)
    for line in txt.split(u"\n"):
        line = TAG.sub(u"", line.strip())
        if line and line[0].isalnum() and len(line) > min_length:
            char_ratio = float(sum(ch.islower() for ch in line)) / sum(not ch.isspace() for ch in line)
            if char_ratio > min_char_ratio:
                yield line

def pre_filter(content):
    return "\n".join([line forCanterbury debutant Jake Averillo took the total number of people inside the stadium to 241.

After more than 25 years of covering the game, I knew most of the people in the cavernous stadium.

Sitting on their own in front of Green’s coaches box, Averillo’s parents, Mick and Bev, and his girlfriend, Charli, were easy to identify and I was interviewing them at full-time when NRL.com photographer Grant Trouville phoned to suggest they come to the fence for a photo with Jake.

Besides Green and Bulldogs coach Dean Pay, those not playing or officiating were either on the sideline or behind the fence.

It was close enough to hear the laughter in the Cowboys camp when Parr landed on his backside when his seat was surreptitiously moved or to be able to


pZVH14 DNAs in the transformed and tumor cells. Chromosome analysis identified the tumors to be of human origin. Tumor cells showed some chromosomal aberrations. Tumors were diagnosed as poorly differentiated carcinomas by histological analysis. Further studies are in progress to map the transforming genes and to identify the mechanism of transformation.legal-system is a software-system, here are some
similarities:

\- Both begin as simple systems and become more sophisticated to account for
more conditions.

\- Both use a language of logic to determine how things happen.

\- Both _usually_ only add more code, not delete old code.

There are many subtleties in Law, but in essence it's just a set of rules
(albeit complex) which a society has to live by. The system I'm proposing
would not be simple, and all-encompassing, but it should be easy to query:

\- Laws/regulations

\- Related precedence (cases, trials)

\- History of changes

Maybe it could simply be a CMS which links to legitimate government websites.
I just thought it could be made simpler to digest for _citizens_ (not lawyers)
with software...


factors to consider when assessing the E-M5’s autofocus performance and speed.

First up is the camera’s design. This isn’t a DSLR as there’s no mirrorbox to reflect light onto either a phase-detection focus system or an optical viewfinder. Instead the mirrorless design entails that the light lands onto the sensor where contrast-detect autofocus takes place and the signal can also be sent to the rear screen and/or the electronic viewfinder.

Secondly the type of focus (single or continuous), lighting conditions and the lens used and at which focal length will all have an impact as to how responsive the autofocus system is.

We’re pleased to report that autofocus is darn quick for the most part. In "single" autofocus subjects nip into sharp focus in no time, though, arguably, the Nikon V1light, though it won't work for all given situations.

Compact system cameras and contrast-detection autofocus as a whole perform differently from DSLR systems, and it’s here that the OM-D’s hefty price tag may prove too much for certain snappers. In general the OM-D will better its compact system camera bredren, but the type of subjects you intend to shoot will determine whether the OM-D is the right camera for you.

Image Quality: Highest resolution Olympus yet

Despite all the fancy features and design, can the E-M5 take a decent picture? It’s the first Olympus camera (outside of compacts) to break the long-standing 12-megapixel barrier, offering the same 16-megapixel sensor as found in the Panasonic Lumix G3.

Of course Olympus has put its own stamp on the hardware: the latest TruPic VI engine


modes, Olympus has a range of art filters. Ranging from sepia to dramatic tone and soft focus to diorama, there are dozens of in-camera options. It's possible to art filter bracket and use the mode when using Raw + JPEG (though the raw file will remain unchanged). Some are quirky, others are fun, most are of genuine use rather than some of the gimmicky modes offered by other competitors' cameras.

Verdict

Sleek, stylish and a classy performer – there’s not much to dislike about the Olympus OM-D E-M5.

It’s not problem-free though: the battery life is, as per all existing compact system cameras, poor. Continuous autofocus won’t beat a DSLR and in dim conditions will struggle or fail entirely; an electronic viewfinder won’t suit all tastes; there's no pop-up flash; and,Soldiers from the 2nd Battalion, 23rd Infantry Regiment provide security near their armored vehicle in Afghanistan on Sept. 21, 2018, nearly 17 years after the conflict began. (Spc. Christopher Bouchard/Army)

Gallego, D-Ariz. and a Marine Corps veteran who served in combat in Iraq, has been a vocal critic of the “perpetual war” in the recent years. In a statement this weekend, he said military and political leaders need to find a way to put a stop to America’s longest military fight.

“It’s clear that continuing on the current course is not in our national interest,” he said. “American troops should come home.

“Our objectives following (the Sept. 11, 2001 attacks) were to destroy al-Qaida, kill Osama bin Laden, and prevent a recurrence of an ungoverned space in Afghanistan that allowed for


Taiatari

is a Kendo movement, literally meaning to hit (ataru) with the body (tai). It is a collision move used to break the kamae and therefore the defense of the opponent.

A correct taiatari is executed with the sword held vertically and the fists held firmly in front of the navel or slightly higher. The force comes from the legs driving the body forward, rather than the arms pushing the opponent away. During practice, a person receiving a taiatari should hold firm. Moving back to absorb the shock could be dangerous depending on the intention of the taiatari.

Category:Kendoto 3 and 10 respectively.
The model correctly learns the weight(slope), but is unable to learn the bias. Where is the error?

A:

The main problem is that you are feeding just one sample at a time to the model. This makes your optimizer very inestable, that's why you have to use such a small learning rate. I will suggest you to feed more samples in each step.
If you insist in feeding one sample at a time, maybe you should consider using an optimizer with momentum, like tf.train.AdamOptimizer(learning_rate). This way you can increase the learning rate and reach convergence.


The clinical significance of Aurora-A/STK15/BTAK expression in human esophageal squamous cell carcinoma.
Aurora-A/STK15/BTAK (Aurora-A) encodes a Serine/Threonine kinase associated with chromosomal distribution, and its up-regulation induces chromosomal instability thereby leading to aneuploidy and cell transformation in several types of cancer. In this study, we investigated the role of Aurora-A in human esophageal squamous cell carcinoma (ESCC). The expression levels of Aurora-A mRNA were compared in 33 ESCC tissues with that in corresponding normal esophageal epithelium by semiquantitative reverse transcription-PCR, and the distribution patterns and expression levels of Aurora-A protein were immunohistochemically investigated in the ESCC tumors of 142 patients. The results were then separately compared with the clinicopathologic findings of the patients, and the expression of Aurora-A was examined in nine ESCC cell lines and a normal esophageal epithelialimages with vivid

This pattern includes a lined jacket with sleeve variations and a close-fitting, A-line dress with length variations. The perfect outfit for a very special party occasion. Create using satin, peau de soie, crepe and novelty sequins.

Pls Single Fluorescent 2-pin G23 5w on other UK sites

Pls Single Fluorescent 2-pin G23 5w on USA sites

The gorgeous Epsom 2-light lighting fixture makes a great addition to any interior. This stunning light is a wonderful way to add beauty and brilliance to your home. Setting: Indoor Fixture finish: Chrome Number of lights: Two (2) Requires two (2) 5W-415 lumen LED (included) Dimensions: 4 inches long x 16 inches wide x 7 inches high

Off to the gym or out for a walk? This is the perfect look for you! ; Relaxed


Sleeve Running top is designed to keep you warm in cold conditions. Made of lightweight Regulite fabric this base layer features a 1/2 zip and wicks sweat away to keep you dry and comfortable. The cut and sew construction features flat-locked seams to prevent irritation. - A.D. Long sleeve running top Thermal layering item to keep you warm Fabric with added

Weve created a soft tweed to make a comfortable wearable fabric that is perfect for this single breasted blazer. In a classic herringbone and lined with a Joules signature floral print this shorter smart jacket is a key investment piece that will be worn season after season.

\Capstar (nitenpyram) kills nearly 100% of fleas in less than 8 hrs. It has no side effects or contraindications. Safe for pregnant

Google, Microsoft ask German government to address spying during Obama visit - mrich
http://zeenews.india.com/news/world/berlin-still-has-questions-after-us-internet-firm-spy-talks_855115.html

======
mrich
This has also been widely reported in German media, unfortunately this was the
best English article I could find.

German: [http://www.spiegel.de/netzwelt/netzpolitik/treffen-mit-
minis...](http://www.spiegel.de/netzwelt/netzpolitik/treffen-mit-ministern-
internetfirmen-bitten-merkel-um-hilfe-a-905822.html)


 With the ball he took 7 wickets at a bowling average of 34.14, with best figures 3/33.

References

External links
Jonny Hughes at ESPNcricinfo
Jonny Hughes at CricketArchive

Category:1985 births
Category:Living people
Category:Sportspeople from Slough
Category:Alumni of Loughborough University
Category:English cricketers
Category:Buckinghamshire cricketers
Category:Loughborough University cricketers---
author:
- 'Shaohan Feng, , Wenbo Wang, , Zehui Xiong, , Dusit Niyato, , Ping Wang,  and Shaun Shuxun Wang'
bibliography:
- 'bibfile.bib'
title: 'On Cyber Risk Management of Blockchain Networks: A Game Theoretic Approach'
---

the past few years, blockchain technologies have attracted tremendous attention from both industry and academia for distributively providing the irreversible, tamper-evident database of tokenized asset transactions [@dinh2017untangling]. Furthermore, with the smart contracts [@bartoletti2017empirical] enabled on top of the decentralized consensus [@dinh2017untangling], blockchains are envisaged to be the “game changer” in various areas ranging from Peer-to-Peer (P2P) resource allocation/trading, e.g., distributed cloud storage [@7966965], to financial services, e.g., digital identity management [@7961146] and online markets for crowdsourcing services [@8332496]. Although with the advantages such as open access, disintermediation, and pure self-organization, open-access/permissionless blockchains rely on the condition of honest majority to guarantee the data integrity and service security, especially


when the Nakamoto consensus protocol based on proof-of-work (PoW) is adopted [@dinh2017untangling]. Since permissionless blockchain networks admit no identity control, they can be vulnerable to a series of insider attacks by malicious consensus nodes [@conti2017survey]. Among different types of attacks, double spending [@Karame:2012:DFP:2382196.2382292] is the most fundamental one and can be executed through various attacks such as goldfinger attacks, netsplit attacks and brute-force attacks [@conti2017survey]. In brief, a double-spending attacker attempts to simultaneously spend the same set of blockchain tokens in two different transactions. This can be performed by first persuading part of the network and the transaction receiver to confirm one transaction, and then persuading the majority of the network to override that transaction with a conflicting transaction spending the same set of tokens. In other words, double-spending attacks are executedattackers. With these studies, it is now possible to estimate the probability of successful double spending and evaluate the potential risks transferred to the cyber-insurers.

Furthermore, under the condition that the probability distribution of risk can be estimated, the authors in [@wang1995insurance] proposed a risk-adjusted premium for pricing risks based on the Proportional Hazard (PH) transform, namely, a power transform in the decumulative distribution function of the risks. Since the PH transform satisfies the elementary principles of assigning premiums, i.e., scale-invariance and translation-invariance, it has been adopted in a number of works concerning the premium determination. In addition, a class of premium functions which are comonotonicity additive and stochastic dominance preservative were studied in [@wang1996premium]. Therein, the premium determination method based on the PH transform was generalized with an axiomatic approach,


provider buys the cyber-insurance, the risk of double-spending attack will be transferred to the cyber-insurer. By adopting the concept of risk-adjusted premium in [@wang1996premium], the cyber-insurer dynamically determines the price, i.e., premium, of its cyber-insurance product according to the insurance risk distribution. According to our previous discussion, the cyber-insurer has an insurance risk, i.e., paying the claim of $\frac{T}{{{T_{\rm{0}}}}}{\bar{h}} N_{\rm{T}} q$ with the probability of ${\rm{P}}\left( {\bar h} \right)$ given by (\[Eq:attack\_probability\_model\]). Then, the expected loss for the cyber-insurer can be formulated as follows: $$\label{Eq:expected_claim_insurer}
\footnotesize{\begin{aligned}
{{\rm{E}}_{loss}} &= \int\nolimits_{1/2}^1 {\frac{T}{{{T_{\rm{0}}}}}\bar h{N_{\rm{T}}}q{\rm{P}}\left( {\bar h} \right){\rm{d}}\bar h}  = \frac{T}{{{T_{\rm{0}}}}}{N_{\rm{T}}}q\int\nolimits_{1/2}^1 {\bar h{\rm{P}}\left( {\bar h} \right){\rm{d}}\bar h} \\
 &= \frac{T}{{{T_{\rm{0}}}}}{N_{\rm{T}}}q\left[ {\left. {\bar hF\left( {\bar h} \right)} \right|_{\bar h = 1/2}^{\bar h = 1} - \int\nolimits_{1/2}^1 {{\rm{F}}\left( {\bar h} \right){\rm{d}}\bar h} } \right] \\
 &={\bar h} \right)\left\{ {\begin{aligned}
&{ > 0,}&{\bar h > \frac{1}{2}},&\\
&{ = 0,}&{\bar h = \frac{1}{2}},&\\
&{ < 0,}&{\bar h < \frac{1}{2}}.&
\end{aligned}} \right.}$$ The conditions in (\[Eq:sigma\_1\]) indicates that with ${\bar{h}} > \frac{1}{2}$, the blockchain provider’s effort in investing the computing resource effectively reduces the successful attack probability. Consequently, the probability of the cyber-insurer paying the claim to the blockchain provider is also reduced. Then, keeping the highest premium has a negative effect on the cyber-insurer’s payoff, e.g., by hurting its reputation or curbing the incentive for the blockchain provider to buy the insurance. Under the other two conditions in (\[Eq:sigma\_1\]), the lack of enough investment in infrastructure of the blockchain provider will induce higher probability of being successfully attacked, hence leading to a positive effect on the cyber-insurer’s payoff due


{{\rm{P}}\left( \theta  \right){\rm{d}}\theta } } \right]\left\{ {1 + \frac{1}{\gamma }\left[ {1 - \int\nolimits_{1/2}^t {{\rm{P}}\left( \theta  \right){\rm{d}}\theta } } \right]} \right\}{\rm{d}}t.
\end{aligned}$$

Following the same procedure in the proof to Theorem \[Th:existence\_for\_leader\_game\], from (\[eq\_intermediate\_negative\]) we obtain the condition of negative definiteness as

$\gamma \ge \ln2$

. Therefore, with the two negative definite blocks on the diagonal positions and all-zero blocks on the off-diagonal positions,

${\bf{J}}_1$

in (\[Eq:partition\_jacobian\_matrix\_leader\_game\]) is a negative definite matrix.

After defining $$\footnotesize{\begin{aligned}
&{{\bf{R}}_1} =\\
&\left[ {\begin{array}{*{20}{c}}
{\bf{I}}&{\bf{0}}&{\bf{0}}\\
{{{\bf{0}}^ \top }}&1&\begin{aligned}
 &- 3{\left( {\overline h  - \frac{1}{2}} \right)^2}\left[ {\left( {\beta  + 1} \right){\gamma ^\beta } - \beta {\gamma ^{\beta  - 1}}} \right]\\
 \times &\left\{  - {{2\left( {\overline h  - \frac{1}{2}} \right)}^3}\right\}^{ - 1}\\
 \times&\left[ {\beta \left( {\beta  + 1} \right){\gamma ^{\beta  - 1}} - \beta \left( {\beta  - 1}\right){\gamma ^{\beta  - 2}}} \right]^{ - 1}
\end{aligned}\\
{{{\bf{0}}^ \top }}&0&1
\end{array}} \right],
\end{aligned}}$$ we can obtain the congruent matrix of

${\bf{J}}_2$

in (\[Eq:partition\_jacobian\_matrix\_leader\_game\]) as shown in (\[Eq:congruent\_matrix\_J\_2\]). In (\[Eq:congruent\_matrix\_J\_2\]), we observe that

${ - {{2\left( {\overline h  - \frac{1}{2}} \right)}^3}\left[ {\left( {\beta  + 1} \right)\gamma  - \left( {\beta  - 1} \right)} \right]\beta {\gamma ^{\beta  - 2}}}<0$

. Then, to ensure the negative semidefiniteness of

${\bf{J}}_2$

, we need the following inequality to hold:

$$\label{eq_intermediate_bound}
  - \frac{{2a}}{{{{\left( {1 - \bar h} \right)}^3}}} + \frac{{9{{\left( {\overline h  - \frac{1}{2}} \right)}^4}{{\left[ {\left( {\beta  + 1} \right){\gamma ^\beta } - \beta {\gamma ^{\beta  - 1}}} \right]}^2}}}{{{{2\left( {\overline h  - \frac{1}{2}} \right)}^3}\left[ {\beta \left( {\beta  + 1} \right){\gamma ^{\beta  - 1}} - \beta \left( {\beta  - 1} \right){\gamma ^{\beta  -


blockchain protocol.,” in [*NSDI*]{}, 2016, pp. 45–59.

M. Rosenfeld, “Analysis of hashrate-based double spending,” , 2014.

C. Grunspan and R. P[é]{}rez-Marco, “Double spend races,” , 2017.

S. Wang, “Insurance pricing and increased limits ratemaking by proportional hazards transforms,” , vol. 17, no. 1, pp. 43–54, 1995.

S. Wang, “Premium calculation by transforming the layer premium density,” , vol. 26, no. 1, pp. 71–92, 1996.

D. Denneberg, “Premium calculation: Why standard deviation should be replaced by absolute deviation,” , vol. 20, no. 2, pp. 181–190, 1990.

G. O. Karame, E. Androulaki and S. Capkun, “Double-spending fast payments in bitcoin,” in [*Proceedings of the 2012 ACM conference on Computer and communications security*]{}. ACM, 2012, pp. 906–917.

S. Nakamoto, “Bitcoin: A peer-to-peer electronic cash system. bitcoin,” 2009.

F. Bloch and N. Qu[é]{}rou, “Pricing in social networks,” , vol. 80, pp. 243–261, 2013.

F. Bloch, G. Genicot and D. Ray, “Informal insurance in social networks,” ,vol. 143, no. 1, pp. 36–58, 2008.

A. Simsek, A. Ozdaglar and D. Acemoglu, “On the uniqueness of solutions for nonlinear and mixed complementarity problems,” Tech. [R]{}ep., Massachusetts Institute of Technology, 2005.

A. Berman and R. J. Plemmons, , SIAM, 1994.

M. J. Osborne, , vol. 3, Oxford university press New York, 2004.

G. Scutari, F. Facchinei, J.-S. Pang and D. P. Palomar, “Real and complex monotone communication games,” , vol. 60, no. 7, pp. 4197–4231, 2014.

R. Zhang, Q. Zhu and Y. Hayel, “A bi-level game approach to attack-aware cyber insurance of computer networks,” , vol. 35, no. 3, pp. 779–794, 2017.

G. Debreu, “A social equilibrium existence theorem,” , vol. 38, no. 10, pp. 886–893, 1952.

P. Shi, “Summary of what��s known about convergence in concave games,” April 10, 2009.

[^1]: For example, Amazon AWS provides the blockchain infrastructures through its partner ecosystem [@AWS2018].

[^2]: Note here that the uniform pricing


of citizens to be deemed as suspect, and a Maoist. In this bleak, and miasmic world view propounded by the respondents in the instant case, historian Ramchandra Guha, noted academic Nandini Sunder, civil society leader Swami Agnivesh, and a former and well reputed bureaucrat, E.A.S. Sarma, were all to be treated as Maoists, or

supporters of Maoists. We must state that we were aghast at the blindness to constitutional limitations of the State of Chattisgarh, and some of its advocates, in claiming that any one who questions the conditions of inhumanity that are rampant in many parts of that state ought to necessarily be treated as Maoists, or their sympathizers, and yet in the same breath also claim that it needs the constitutional sanction, policies under of our Constitution,That an expert body constituted by the Planning Commission of India, Government of India, uses the word “rapacious”, connoting predation for satisfaction of inordinate greed, and subsistence by capture of living prey, is revelatory of the degree of human suffering that is being visited on vast sections of our fellow citizens. It can only be concluded that the expert body, in characterizing the state of

existence of large numbers of our fellow citizens, in large tracts of India, as “sub-human,” is clearly indicating that such an existence is not merely on account of pre-existing conditions of significant material deprivation, but also that significant facets that are essential to human dignity have been systematically denied by the forces and

mechanisms of the developmental paradigm unleashed by the State. Equally poignantly, and


does enable us, as constitutional adjudicators to recognize, and prevent, the emergence, and the institutionalization, of a policing

paradigm, the end point of which can only mean that the entire nation, in short order, might have to gasp: “The horror! The horror!”

22.It is in light of the above that we necessarily have to examine the issues discussed below, and pass appropriate orders. We have heard at length the learned senior counsel, Shri. Ashok H. Desai, appearing on behalf of the

petitioners, and learned senior counsel, Shri. Harish N. Salve and Shri. M.N. Krishnamani appearing for the State of Chattisgarh. We have also heard learned Solicitor General of India, Shri Gopal Subrahmanyam, appearing for the Union of India.

23.The instant writ petition was filed, in 2007, by: (i) Dr. Nandini Sunder, atried to visit the said villages to distribute humanitarian aid, and gain firsthand knowledge of the situation, they were attacked by members

21 of “Salwa Judum” in two separate by the incidents, Chief and that, of

notwithstanding

assurances

Minister

Chattisgarh that they will be provided all the security to be able to undertake their journey and complete their

tasks, and notwithstanding the presence of security forces, the attacks were allowed to be perpetrated. Swami Agnivesh, it is also reported, and prima facie appears, is a social activist, of some repute, advocating the path of peaceful resolution of social conflict. It also appears that Swami Agnivesh has actually worked towards the release of some police personnel who had been kidnapped by Naxalites in Chattisgarh, and the same has also been acknowledged by a person no


or to obey such lawful order or direction as may be given to him for the performance of his duties, he shall be liable, upon conviction before a Magistrate, to a fine not exceeding fifty rupees for every such neglect, refusal or disobedience.”

37.In the year 2007, the State of Chattisgarh enacted the Chattisgarh Police Act, 2007 and some relevant portions of the same are noted below.

Section 1(2): “It shall come into force from the date of its publication in the Official Gazette; Section 2(n): “Police Officer” means any member of the Police Force appointed under this Act or appointed before the commencement of this Act for the State and includes members of the Indian Police Service or members of any other police organization on deputation to the Statematters affecting public peace and crime; (k) To provide security to public authorities in discharging their functions; (l) To perform all such duties and discharge such responsibilities as may be enjoined upon him by law or by an authority empowered to issue such directions under any law.

Section 24: Every police officer shall be considered to be always on duty, when employed as a police officer in the State

32 or deployed outside the State. Section 25: No police officer may engage in an employment or office whatsoever, other than his duties under this Act, unless expressly permitted to do so in writing by the State Government. Section 50 (1) The State government may make rules for carrying out the purposes of this Act: Providing that existing State Police regulations


the petitioners, that thousands of tribal youth are being appointed by the State of Chattisgarh, with the consent of the Union of India, to

36 engage in armed conflict with the Maoists/Naxalites. The facts as stated in the affidavits of the State of

Chattisgarh, and Union of India themselves reveal that, contrary to the assertions that the tribal SPOs are

recruited only to engage in non-combatant roles such as those of spotters, guides, intelligence gatherers, and for maintenance of local law and order, they are actually The fact

involved in combat with the Maoists/Naxalites.

that both the State of Chattisgarh and the Union of India themselves remote acknowledge in that the relief SPOs camps, and the and

villages,

which

these

are

recruited

directed to work in, have been subject to thousands of attacks clearly indicates that in every suchModern counter-insurgency requires use of sophisticated analytical tools, analysis of data, surveillance etc. According to various reports, and indeed the claims of the State itself, Maoists have been preparing themselves on more scientific lines, and gained access to sophisticated claims that weaponry. these That the with State of or Chattisgarh no formal

youngsters,

little

education, are expected to learn the requisite range of analytical skills, legal concepts and other sophisticated aspects of knowledge, within a span of two months, and that such a training is sufficient for them to take part in counter-insurgency against the Maoists, is shocking. 46.The State of these Chattisgarh tribal has itself as SPOs stated that in for

recruiting

youths

“preference

those who have passed the fifth” standard has been given. This clearly implies that some, or many, who have been


endanger the human

rights of others in the society. 60.In light of the above, we hold that both Article 21 and Article 14 of the Constitution of India have been violated, and will continue to be violated, by the appointment of tribal youth, with very little education, as SPOs engaged in counter-insurgency education activities. The lack with of adequate to

prior

incapacitates

them

respect

acquisition of skills, knowledge and analytical tools to function effectively as SPOs engaged in any manner in

counter-insurgency activities against the Maoists. 61.Article 14 is violated because subjecting such youngsters to the same levels of dangers as members of the regular force better who have better and a educational because better of backgrounds, better to receive

training, possess

educational benefit from

backgrounds

capacity

training that is appropriate for the duties to be performed in counter insurgencya

position to benefit from an appropriately designed training program, that is commensurate with the kinds of duties, liabilities, disciplinary code and dangers that they face, to their lives and health. Consequently, appointing such youngsters as SPOs with duties, that would involve any

counter-insurgency activities against the Maoists, even if it were claimed that they have been put through rigorous training, would be to endanger their lives. observed that: in Olga Tellis v. Bombay This Court has Corporation1

Muncipal

“ “Life”, as observed by Field J., in Munn v. Illinois means something more than mere animal existence, and the inhibition against the deprivation of life extends to all those limits and faculties by which life is enjoyed.” 63.Certainly, within the ambit of all those “limits and

faculties by which life is enjoyed” also


delete _p;
         delete _count;
      }
      _p     = c._p;
      _count = c._count;
      _count->increment();
   }
   return *this;
}

/*
 * Destructor.
 * Delete the object if no other counted pointers refer to it.
 */
template <typename T>
counted_ptr<T>::~counted_ptr() {
   if (_count->decrement() == 0) {
      delete _p;
      delete _count;
   }
}

/*
 * Smart pointer dereference.
 * Return object by reference.
 */
template <typename T>
inline T& counted_ptr<T>::operator*() const {
   #if LANG__POINTERS__COUNTED_PTR__CHECK_DEREFERENCE
      if (_p == NULL)
      If a project is to complex or too involved for a homeowner, it would be a good idea to consider a licensed contractor. When hiring a contractor, be sure to obtain at least three separate bids from three different contractors. Also, be sure to ask for and check references.

As long as the business information (address, ownership) remains the same, you may reactivate a business license by paying the new license fees and any past due fees and taxes. There must also be a current business license application on file.

When your City tree diameter is the same size as the stake diameter the homeowner should remove both stakes and discard. The homeowner is also responsible to keep the City tree watered and fertilized during its growing season.

The City is


while responding Code Three, an emergency response vehicle must have all emergency lights on and the siren sounding. A Code Three response is initiated when life, property or the environment is in immediate jeopardy (ie. bleeding, breathing problems, fire).

Sometimes several units are dispatched to the same incident. The first unit may have arrived on the scene, surveyed the situation and informed the dispatcher that the situation was under control. All other responding units were cancelled and put back into service, ready to take another call. Most likely, when you see an emergency vehicle go "Code 3" (lights and siren) through an intersection and then slow down and turn the emergency lights off, they have been cancelled from the call they were going on.

Inform the apartment management of theSafety or an Emergency Services candidate is also required to undergo a psychological evaluation and for some positions a polygraph test.

View our Utility Fee Schedule (PDF). For information on multi-family, industrial, commercial, service connections outside of the City limits, and low income rates call the Finance Department at 209-538-5757.

There is also a drive-up bill payment box located at City Hall on the corner of Second and Magnolia Streets. A traffic lane on the right side of the box allows you to easily deposit payments from the driver’s side of your vehicle.

Pay in person at the counter of the Finance Department located at 2220 Magnolia Avenue.

If a customer's service is shut off for nonpayment and the customer tampers with the service by reconnecting it, a tampering charge of $100


or less and no larger than 6 inches in diameter) on the street, one foot from the gutter at least one day before your collection day. Do not place leaves and limbs in blue recycling toter.

Yes, by appointment, 209-537-1500. The program is for Ceres residents living in single family homes, duplexes, triplexes, and four-plexes on one piece of property. The program is not for apartment complexes, businesses, industries, schools, churches, or residents living outside of Ceres. The program provides a convenient way to get rid of certain items that cannot fit into waste-wheelers. The program can be used twice each calendar year, and has specific requirements.

With homes built within the last 25 years there will be an "S" or "L" stamped on the curb in front of the!= nil {
			return err
		}

		return nil
	})

	s.OnManifestExpire(func(ref reference.Reference) error {
		var r reference.Canonical
		var ok bool
		if r, ok = ref.(reference.Canonical); !ok {
			return fmt.Errorf("unexpected reference type : %T", ref)
		}

		repo, err := registry.Repository(ctx, r)
		if err != nil {
			return err
		}

		manifests, err := repo.Manifests(ctx)
		if err != nil {
			return err
		}
		err = manifests.Delete(ctx, r.Digest())
		if err != nil {
			return err
		}
		return nil
	})

	err = s.Start()
	if err != nil {
		return nil, err
	}

	cs, err := configureAuth(config.Username, config.Password, config.RemoteURL)
	if err != nil {
		return nil, err
	}

	return &proxyingRegistry{
		embedded:  registry,
		scheduler: s,
		remoteURL: *remoteURL,
		authChallenger: &remoteAuthChallenger{
			remoteURL: *remoteURL,
			cm:        challenge.NewSimpleManager(),
			cs:        cs,
		},
	}, nil
}

func (pr *proxyingRegistry) Scope() distribution.Scope {
	return distribution.GlobalScope
}

func (pr *proxyingRegistry) Repositories(ctx context.Context, repos []string, last string) (n int, err error) {
	return pr.embedded.Repositories(ctx, repos, last)
}

func (pr *proxyingRegistry) Repository(ctx context.Context, name reference.Named) (distribution.Repository, error) {
	c := pr.authChallenger

	tkopts := auth.TokenHandlerOptions{
		Transport:


civil rights action pursuant to 42 U.S.C. § 1983 against
Anderson, Irving, Jimenez, Leifeld, and Ramsey County for (1) use of excessive force
during the escort to seclusion, (2) denial of procedural due process for Hall’s
placement in seclusion, and (3) denial of medical care in the delayed treatment of
Hall’s leg. Hall also brought state-law claims for assault, battery, false imprisonment,
and negligence. Appellees moved for summary judgment asserting qualified
immunity. The district court granted summary judgment on Hall’s section 1983

                                          -3-
claims, finding Hall failed to demonstrate a violation of a constitutional503 U.S. 115, 125, 112 S. Ct. 1061, 117 L. Ed. 2d 261 (1992)) (internal
quotation marks omitted).

       In the context of substantive due process, an individual must overcome a very
heavy burden to show a violation of the Fourteenth Amendment. To balance
competing interests in a substantive due process analysis, “the question is not simply
whether a liberty interest has been infringed but whether the extent or nature of the
[infringement] . . . is such as to violate due process.” Moran v. Clarke, 296 F.3d 638,
647 (8th Cir. 2002) (en banc) (alteration in original) (citation omitted) (internal
quotation marks omitted). To establish a violation, the “plaintiff must demonstrate
both that the official’s conduct was conscience-shocking, and that the official violated
one or more fundamental rights that are deeply


rooted in this Nation’s history and
tradition, and implicit in the concept of ordered liberty, such that neither liberty nor
justice would exist if they were sacrificed.” Norris, 494 F.3d at 638 (quoting
Slusarchuk v. Hoff, 346 F.3d 1178, 1181-82 (8th Cir. 2003)) (internal quotation marks
omitted).

                                          -5-
       To satisfy the conscience-shocking standard,3 a government official’s conduct
must be “so egregious, so outrageous, that it may fairly be said to shock the
contemporary conscience.” Cnty. of Sacramento v. Lewis, 523 U.S. 833, 847-48 n.8,
118 S. Ct. 1708,140 L. Ed. 2d 1043 (1998). “[C]onduct intended to injure [an
individual] in some way unjustifiable by any government interest is . . . most likely to
rise to the conscience-shocking level.” Id. at 849, 118 S. Ct. 1708, 140 L. Ed. 2d
1043. But when the acts of a government official fall “within the middle range . . .
something more than negligence but less than intentional conduct”4 the “totality of the
facts in a given case” must be assessed to determine whether the behavior is

      3
        The Supreme Court recently published its decision in Kingsley v.
Hendrickson, 135 S. Ct. 2466 (2015), holding a pretrial detainee need only show a
government official’s use of force was objectively unreasonable in a section


    4
        Hall relies on the “deliberate indifference that shocks the conscience”
standard. We have held that the middle range of conduct that could shock the
conscience “in some contexts” includes egregious cases of “deliberate indifference,
recklessness, or gross negligence.” Bonebrake v. Norris, 417 F.3d 938, 942 (8th Cir.
2005) (internal quotation marks omitted). But we have never applied the “deliberate
indifference that shocks the conscience” standard in the context of an excessive force
claim brought by an involuntarily committed individual. See Norris v. Engles, 494
F.3d 634, 638-39 (8th Cir. 2007) (articulating the standard above for a substantive
due process claim brought by an individual placed, involuntarily, in protective
custody). Even if we assume, arguendo, it is proper to analyze “deliberate
indifference that shocks the conscience” inthis context, Hall’s claim would also fail.

                                           -6-
conscience shocking. Id. at 849-50, 118 S. Ct. 1708, 140 L. Ed. 2d 1043 (citations
omitted) (internal quotation marks omitted). Determining whether conduct is
conscience shocking “is a question of degree.” Moran, 296 F.3d at 647 (citation
omitted) (internal quotation marks omitted).

      In general, substantive due process is concerned with violations of
      personal rights . . . so severe . . . so disproportionate to the need