Response to: Bias in the use of a SSClow/CCR3pos gate to capture basophils in chronic urticaria?
A response to Chirumbolo S, Bjørklund G, and Vella A, Bias in the use of a SSClow/CCR3pos gate to capture basophils in chronic urticaria? Immunobiology, 224(3), 2019, 353-354.e sigh as recruitment maneuvers. He gradualy reduced tidal volumes from 8 to 2 ml/kg and increased PEEP from 10 to 25 cmH~2~O. When PEEP of 25 cm H~2~O was reached, CPAP of 30 cm-H~2~O was applied for 30 seconds. This was a succssessful manouver, oxigenation was incresed and patients were hemidinamically stabile. Lots of authors ([@R11], [@R17], [@R19]) showed that e sigh was safe and efficiant method for improvment in oxygenation. Constantin et al. ([@R28]) compared two recruitment maneuvers, e sigh with PEEP 10 cm H~2~O above LIP for 15 minutes and CPAP 40 cmH~2~O for 40 seconds.

Both manouvers approved oxygenation but CPAP was assossiated with hemodynamic instability. Khaled M Mahmoud and Amany S Ammar ([@R28]) also proved that extended sigh was more effective in oxygenation of


These folks should not be
making aircraft used by living, breathing human beings.

The stock holders Boeing is beholden to, that clamor for this cost cutting,
should pay.

~~~
ericd
The stockholders are you and I, via retirement plans.

~~~
echelon
Our investment portfolios and retirement plans can be rebalanced. Those that
died in the two Max crashes are gone forever.

This isn't cheating on emissions. We have to send a strong message.

~~~
ericd
If you mean just lose money when you say the stockholders should pay, then
yeah, whatever. But if you mean that they should be held responsible, I think
that’s absurd. That’s what I meant by my response.

Losing 1000 people is a tragedy, and those responsible should be held
responsible. But a company like Boeing is a huge machine with many people
working diligently on extremely complicated products, the vast majority of
whomdidn’t touch this faulty system at all. Which is to say you shouldn’t
throw the baby out with the bath water.

------
durnygbur
"These are the rates in India and Eastern Europe, we're paying well above the
market actually, so we are getting crème de la crème" \- some directors and
managers at Boeing, probably.

------
xerxex
I wonder if this is unchecked laissez faire capitalism at work? Nobody wants
to fly on Boeing 737 Max anymore but this has cost hundreds of lives to get to
this point.

~~~
leetcrew
there's very little "laissez-faire" about the relationship between Boeing and
the US government.

~~~
AlexCoventry
There was definitely regulatory capture which led to lax FAA oversight,
though. Maybe a free-market fundamentalist would argue that they would have
done better if they weren't dragged down by all that red tape, but it suggests
to me that a looser regulatory


mice. We are hopeful these metabolites can be targeted for potential future therapies.”

To explain the mechanism of gut-brain communication, the investigators identified communities of bacteria linked with increased levels of cresol, an organic compound capable of passing the blood-brain barrier.

When the precursors of cells that form myelin were exposed to cresol, they lost their capacity to produce myelin, indicating that a gut-derived metabolite had an impact in the formation of myelin in the brain.

More studies are necessary to translate the results from this study into humans, and to identify bacterial communities with the potential to encourage the production of myelin.

MS is a demyelinating disease in which the insulating covers (myelin) of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts (d) 2/17  (e) 2/25  (f) 0.051
c
Which is the closest to -546685?  (a) -0.1  (b) -2/9  (c) 2
b
Which is the closest to -1671?  (a) -4/15  (b) -15/4  (c) -2/13  (d) -31
d
What is the closest to 5/4 in 0.5, 0.18, 25472/5, 2/9?
0.5
Which is the nearest to 82?  (a) -1.12  (b) 0.3  (c) 2/577
b
Which is the closest to 2?  (a) -0.08426  (b) 0.4  (c) 1/40  (d) -0.2
b
What is the nearest to -0.5 in 4, 56, 0, -8955, -0.3?
-0.3
Which is the nearest to -1?  (a) 2/15  (b) -2  (c) -0.3  (d) -1824  (e) 2/3  (f) -2/5
f
Which is the nearest to -1?  (a) -2/3  (b) 2/13  (c)


a composite number?
False
Let n(b) = 5*b**3 - 17*b**2 - 14*b + 49. Suppose -268 = -13*u - 73. Is n(u) composite?
False
Let x(u) = u**2 - 16*u + 17. Let a be (-2)/(2/(-25)*15/9). Let l be x(a). Suppose -555 = -5*s - 4*b, -3*s + 2*s - l*b = -111. Is s composite?
True
Suppose 0 = 20510*s - 20513*s + 253983. Is s composite?
True
Suppose -4*r = r + 5975. Let i(h) = 247*h + 385. Let j be i(11). Let c = j + r. Is c composite?
False
Suppose 26*t + 48 + 30 = 0. Is (-1)/((-1)/2728*2) + t a prime number?
True
Let z be (5 - 1)/((-6)/(-8943)). Let k = z + -3509. Is k prime?
False
Suppose -1015*j + 1128*j - 15420418 = 11709187. Is j a prime number?
False
Suppose -71*z =designing mass transport pathways is required for O2 . Recently, the importance of pyridinic N for the creation of active sites for ORR and the requirement of hydrophobicity near the active sites have been reported. Based on the increased knowledge in controlling ORR performances, bottom-up preparation of N-doped carbon catalysts, using N-containing conjugative molecules as the assemblies of the catalysts, is promising. Here, the recent understanding of the active sites and the mechanism of ORRs on N-doped carbon catalysts are reviewed.


101 F.2d 604 (1939)
WALLACE'S ESTATE et al.
v.
COMMISSIONER OF INTERNAL REVENUE.
No. 4417.
Circuit Court of Appeals, Fourth Circuit.
January 30, 1939.
*605 Paul F. Myers, of Washington, D. C. (Martin W. Meyer and Thomas J. Fitzgerald, Jr., both of Washington, D. C., on the brief), for petitioners.
John A. Gage, Sp. Asst. to Atty. Gen. (James W. Morris, Asst. Atty. Gen., and Sewall Key and J. Louis Monarch, Sp. Assts. to Atty. Gen., on the brief), for respondent.
Before PARKER and SOPER, Circuit Judges, and CHESNUT, District Judge.
SOPER, Circuit Judge.
The Commissioner of Internal Revenue, in determining the income tax of Mildred F. Wallace for the calendar year 1932, charged her with the receipt of commissions in the sum of $26,860 as executrix of the estate of her husband, and disallowed a deduction of $10,000that the process of liquidation of an estate in the hands of an executor may not be considered the carrying on of a trade or business by the estate, so as to permit the deduction of monies disbursed in payment of the testator's debts from the gross income in order to determine the net income of the estate subject to the payment of income tax. Reference is also made to Blair v. Wilson Syndicate Trust, 5 Cir., 39 F.2d 43, and Crocker v. Malley, 249 U.S. 223, 39 S.Ct. 270, 63 L.Ed. 573, 2 A.L.R. 1601, which hold that trustees, organized to hold and liquidate property, are not associations doing business within the meaning of the income tax law; and also to such cases as Zonne v. Minneapolis


This act is defined as the addition of any non-condimental substance to a food, such substance not constituting a portion of the food. Even this carefully-worded definition is not perfect. Some kinds of salt provisions have so much salt added that some of it has to be removed by soaking, to render the food edible, yet this does not constitute adulteration. Adulteration of food has long been practiced. It is mentioned in the case of bread by Pliny, who also says that difficulty was experienced in Rome in procuring pure wines. Athens had its public inspector of wines. England and France early passed laws to guard against the adulteration of bread, and as far back as the days of Edward the Confessor public punishment was provided for theit is required by many enactments that its presence in butter be medicated on the package. Lard is another adulterant of butter. Cheese is made from skim-milk some times, and cottonseed oil and other cheap fats are substituted for the cream. There are two principal sugar substitutes. One is glucose, with which sugar products are adulterated. It has less than two-thirds the sweetening power of sugar. The other is saccharine. This is the sweetest substance known; it is 230 times sweeter than sugar. It may be regarded as practically harmless. Sugar itself is generally pure. Meat is not much adulterated. It is generally only open to adulteration with preservatives, and cold storage causes these to be little used. It is sometimes dusted over with a preservative while in


in the United States, or +1 585 442 8170 outside of the United States. We are open Monday through Friday between the hours of 8:30AM and 6:00PM, United States Eastern.

Improper dependencies slant policy over a drug’s life span, biasing the development of new drugs, the testing and marketing approval for new drugs, and the monitoring of patient safety after drugs are marketed. This article examines five ways in which the public improperly depend on pharmaceutical firms that compromises the integrity of pharmaceutical policy. Today the public relies on pharmaceutical firms: (1) to set priorities on drug research and development; (2) to conduct clinical trials to test whether drugs are safe and effective; (3) to decide what clinical trial data to disclose to the public; (4) to monitor postInterdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases.
Nonribosomal peptide synthetases are large, complex multidomain enzymes responsible for the biosynthesis of a wide range of peptidic natural products. Inherent to synthetase chemistry is the thioester templated mechanism that relies on protein/protein interactions and interdomain dynamics. Several questions related to structure and mechanism remain to be addressed, including the incorporation of accessory domains and intermodule interactions. The inclusion of nonproteinogenic d-amino acids into peptide frameworks is a common and important modification for bioactive nonribosomal peptides. Epimerization domains, embedded in nonribosomal peptide synthetases assembly lines, catalyze the l- to d-amino acid conversion. Here we report the structure of the epimerization domain/peptidyl carrier protein didomain construct from the first module of the cyclic peptide antibiotic gramicidin synthetase. Both holo


Farm Updates

Heilig Orchards in Mullica Hill, NJ began pruning their trees this past week. Skillfully trained workers prune the entire orchard by hand. Pruning at this stage is extremely important to the health and size of the peach when it comes time for picking.-3 divided by -64.
3/64
Divide 1068 by 6.
178
What is -330 divided by -12?
55/2
Calculate -4 divided by -148.
1/37
What is -73 divided by -10?
73/10
What is -3 divided by -72?
1/24
Calculate -560 divided by -20.
28
Divide -95 by -5.
19
Calculate 6 divided by 930.
1/155
-1295 divided by 35
-37
Divide -204 by -68.
3
-169 divided by 13
-13
Divide 518 by -518.
-1
-1480 divided by 5
-296
11 divided by 166
11/166
Calculate 2607 divided by -3.
-869
Divide


improvements with the community. Renew motivation: At first, some community members thought of the Agency Meetup Days as marketing events, when in reality we were discussing practical problems and solutions. I learned that much of our community is motivated and eager to contribute time and money toward improvements and solutions. I got the impression that these meetings helped re-energize many people.

2015 tour

The success of the 2014 Agency Meetups encouraged us to try to hold more events every year, although the focus will change. What was product improvement in 2014 will turn into joint marketing efforts in 2015.

And we will enlarge the footprint: UK, Austria, and Italy will be new on the 2015 list, with plans for other countries as well.

Regional meetups are a great way to connect toThe object of the invention is to break in and maintain new and used softball and baseball gloves.
In U.S. Pat. No. 4,765,519 a pocket retaining and forming a device includes a strap which has a mid portion to which is attached a ball-like object. The end portions of the strap are connected together with Velcro fasteners to hold the ball-like member in place within the glove pocket. Softballs or baseballs may be attached to the strap.
A similar device is shown in U.S. Pat. No. 5,000,317. In this device, a ball-like member is held in place within the glove by means of a strap extending through a buckle.
In each of these devices, the pocket is formed and maintained merely by having a ball-shaped member held in place within the


programs will continue to function normally.  However, this
introduces an edge case in the following conditions:

* No `'data'` event handler is added.
* The `pause()` and `resume()` methods are never called.

For example, consider the following code:

```javascript
// WARNING!  BROKEN!
net.createServer(function(socket) {

  // we add an 'end' method, but never consume the data
  socket.on('end', function() {
    // It will never get here.
    socket.end('I got your message (but didnt read it)\n');
  });

}).listen(1337);
```

In versions of node prior to v0.10, the incoming message data would be
simply discarded.  However, in Node v0.10 and beyond, the socket will
remain paused forever.

The workaround in this situation is to call the `resume()` method to
trigger "old mode" behavior:

```javascript
// Workaround
net.createServer(function(socket) {

  socket.on('end', function() {
    socket.end('I got yourmessage (but didnt read it)\n');
  });

  // start the flow of data, discarding it.
  socket.resume();

}).listen(1337);
```

In addition to new Readable streams switching into old-mode, pre-v0.10
style streams can be wrapped in a Readable class using the `wrap()`
method.

## Class: stream.Readable

<!--type=class-->

A `Readable Stream` has the following methods, members, and events.

Note that `stream.Readable` is an abstract class designed to be
extended with an underlying implementation of the `_read(size)`
method. (See below.)

### new stream.Readable([options])

* `options` {Object}
  * `highWaterMark` {Number} The maximum number of bytes to store in
    the internal buffer before ceasing to read from the underlying
    resource.  Default=16kb
  * `encoding` {String} If specified, then buffers will be decoded to
    strings using the specified encoding.  Default=null
  * `objectMode` {Boolean}


`encoding` {String} Optional.  If `chunk` is a string, then encoding
  defaults to `'utf8'`
* `callback` {Function} Optional.  Called when the final chunk is
  successfully written.

Call this method to signal the end of the data being written to the
stream.

### Event: 'drain'

Emitted when the stream's write queue empties and it's safe to write
without buffering again. Listen for it when `stream.write()` returns
`false`.

### Event: 'close'

Emitted when the underlying resource (for example, the backing file
descriptor) has been closed. Not all streams will emit this.

### Event: 'finish'

When `end()` is called and there are no more chunks to write, this
event is emitted.

### Event: 'pipe'

* `source` {Readable Stream}

Emitted when the stream is passed to a readable stream's pipe method.

### Event 'unpipe'

* `source` {Readable Stream}

Emitted when a previously established `pipe()` is removed using the
sourceup here,” Clowney added. “Great quarterback. Great system. Just wanted to be part of this organization.”

Clowney, who had final say over his destination due to his refusal to sign a franchise tender, rebuffed the possibility of a trade to the Dolphins, a franchise trying to establish its own new culture under first-year coach Brian Flores. The Eagles were a possibility, too.

“Me and my girl sat down and thought about it like, ‘Would you want to go somewhere else?’“ Clowney told reporters upon his arrival in Seattle. “This might be the greatest situation for me.”

Surely, it helps that Carroll wants no part of an authoritarian, one-size-fits-all dynamic. Never mind that he’ll turn 68 on Sept. 15. He is hardly set in his ways, with a track record for adapting


the overhead buffer 940 with a steady write clock at the overhead bit rate. The output of the overhead buffer 940 is read using a read clock at a “bursty” clock rate, resulting in the creation of a wrapper bit stream 150 composed of recurring wrapper segments 150A–150C. This wrapper bit stream is also fed to the interleaver 930.
At the interleaver 930, each wrapper segment in the wrapper bit stream is inserted into a gap in the gapped bit stream 120. An accelerated clock provided from the clock source 920 can be used to select the appropriate port from which the interleaver 930 is currently reading. By coordinating the acceleration of the overhead bit stream 140 with the acceleration of the payload bit stream 100, the wrapper segmentsof high-speed receivers at an intermediate node is highly undesirable.
In addition, since the receivers are bit-rate/protocol sensitive, it is necessary to deploy multiple such receivers in parallel at any node which purports to handle a large number of bit-rates and protocols or which is claimed to be protocol independent. Since such receivers require a high level of input optical signal, the input to them would need to be switched and/or amplified.
FIG. 1B illustrates an alternative method of carrying overhead information, which reduces amplification requirements and permits the use of low-speed receivers at an intermediate node. Therein is shown a composite signal 165 resulting from low-intensity modulation of the payload bit stream 100 with a narrowband “analog” wrapper signal 155. The wrapper signal 155 can be a line coded


analog signal derived from the signal level of the overhead bit stream 145. Those skilled in the art will appreciate that it is possible to extract the wrapper signal 155 at an intermediate node by accessing the composite signal 165, converting it to electrical form using a low-bandwidth receiver, followed by detection and decoding.
However, the analog wrapper approach has severe limitations of its own. For instance, the superimposition of an intensity-modulated wrapper signal 155 on the payload bit stream 100 results in partial closure of the data “eye” at the end receiver, due to the variation in the signal level of wrapper symbols seen by the receiver. This in turn has the effect of reducing the maximum distance before regeneration of the optical signal is required unless “slow”Simply put, the overhead information carried by an analog wrapper signal forming part of a given composite signal will be lost if the signal passes through the wavelength converting switch 724, unless the analog wrapper is detected at the input of the wavelength converting switch 724 and then re-superimposed on the appropriate signal at the output of the wavelength converting switch 724. However, the added complexity of performing this operation is a disadvantage which compounds the disadvantages arising from the analog wrapper's generally low information capacity.
It should therefore be apparent that the problems associated with carrying and extracting overhead information using conventional analog and digital wrapper techniques in a high-speed transport network are exacerbated when the transport network is equipped with photonic switching nodes.


Q:

Windows can't identify Samsung captivate glide

I've Samsung Captivate Glide (i927). When I try to connect the phone to the PC windows says USB Device unrecognized. I've installed the latest version of Samsung Kies, and also installed Samsung_USB_Driver_for_Mobile_Phones_v1.5.14.0 from the official Samsung site. Still I cannot connect my phone to the PC.
I tried to install the Samsung mobile composite driver manually also. It installed successfully but gives an error that the device cannot start code 10. And again the phone is detected as "Unknown device".
I've also tried to change the PDA USB mode in phoneutils by *#7284#, still no luck.
Can anyone tell me how to solve this problem? I'm using Windows-7 Ultimate 32-bit Desktop computer.

A:

Finally got solution after 2 days of headache. Problem is my USB data cable.of making out is mushing lips together. So, when I tried to french kiss her, she later commented that that will take some getting used to. I guess I struggle with the idea that she never french kissed before. I guess it is possible. I have met a couple other woman over the years that were 'different' kissers, but this is a little extreme. She seems open to 'getting used to it', but I have to admit, I'm a lil blown away that her technique is SO different than mine and most of the other woman I have dated.
Obviously communication is key here, and also making her comfortable to try something she quite possibly NEVER did with a guy she was with for TWELVE YEARS.
Anyone have similar experience


me. I'd try to make out and nothing.
Oh, and my current lover gets a hard on if we make out more than a minute! (;

Gold Member

Haha isn't it awesome how some sexy tongue action gets them hard so fast? Another is that simply talking about things I've done to him in bed give him goosebumps too

With the guy#2 he really made me think of the other wonderous things he could do with that talented tongue of his...if I only knew!!

ISOPC: She could be uncomfortable or just nervous and clueless what to do.Have you asked her if she likes to make out with you? Ask her what she likes that you do to her and what she likes to do to you and you tell her what you likeOKT3-induced nephrotoxicity is associated with release of group II secretory phospholipase A2.
Administration of the murine IgG2a CD3 monoclonal antibody OKT3 exerts a transient nephrotoxic effect. Increased levels of group II secretory phospholipase A2 (sPLA2-II) might account for this nephrotoxicity as sPLA2-II induces the biosynthesis of prostaglandins, vasoactive lipid mediators that influence glomerular haemodynamics and renal function. Furthermore, extracellular phospholipases seem to be involved in proximal tubular cell injury. We studied plasma sPLA2-II levels in relation to circulating creatinine, tumour necrosis factor alpha, interleukin 6 and C-reactive protein levels in 15 renal allograft recipients receiving rejection treatment with OKT3. As a control group, we studied 15 renal allograft recipients receiving rejection treatment with methylprednisolone. A maximal fourfold increase in sPLA2-II levels was observed 48 h after the first OKT3


for today, not only a gift for today, but a gift to be
sought by every Christian who wants the fullness of the Holy Spirit and
the fullness of the blessing of God. It is so much a part of the fabric
of the Charismatic movement that it is one of the primary things that
they endeavor to teach the children in that movement.
Someone
sent me a sample of some Charismatic Sunday school literature which is
designed specifically to teach kindergarten children how to speak in
tongues. It's titled, "I've Been Filled with the Holy Spirit," and it's
an eight page coloring book. One page has a caricature of a smiling
weight lifter with a T-shirt and it says, Spiritman, and under him is
printed 1Corinthians14:4,
"He that speaks in an unknown tongue builds himself up." Another page
features agift of praise. As I used the
unknown language, which God had given me, I felt rising in me the love,
the awe, the adoration, pure and uncontingent, that I had not been able
to achieve in thought out prayer." In other words, I got more out of
prayer I couldn't understand, than I did out of prayer that I could
understand.
A newspaper article on tongues quoted the Reverend
Bill L. Williams of San Jose, he said this, "It involves you with
someone you're deeply in love with and devoted to. We don't understand
the verbiage, but we know we're in communication." If I could just
interrupt and ask you to try that sometime on someone you love very
dearly, and see how effective it is in communication you could probably
judge that statement accurately. He went on to


them speak in his own language." It
wasn't doubletalk, it wasn't gibberish, it wasn't angel talk, it wasn't
celestial speech, it was just different languages.
"And they were
amazed and marveled, saying, 'Why, are not all these who are speaking
Galileans?'" See Galilee was a kind of a hick town area, hay seeds lived
up there. Nobody was educated, they certainly didn't learn languages up
there, they could barely speak their own language. "Aren't these
Galileans? How is it that everybody's hearing them in our own language?
The Parthians and the Medes and the Elamites, and the residents of
Mesopotamia, Judea and Cappadocia, Pontus and Asia, Phrygia and
Pamphylia, Egypt and the districts of Libya around Cyrene, and visitors
from Rome, both Jews and proselytes, Cretans and Arabs; we hear them in
our own languages."
This is incredible. It was very cleartheir own
language. That's all; it wasn't some angel talk, some gibberish, some
gobbleygook, some nonsense talk. Then it says also they were hearing in
their own dialektos, dialects, that also we find used in Acts
chapter 2. So there were unbelievers present at Pentecost hearing God's
message in their own languages and their own local dialects, not
ecstatic gibberish.
Now when you come to 1 Corinthians,
curiously, the King James version has chosen to add the word unknown,
unknown tongue, and some Charismatics have sort of felt that that gave
them the right to say they weren't languages. The King James says, "An
unknown tongue," you'll notice, if you have a New American Standard,
they took the word unknown out. Why? Because it wasn't in the original,
they spoke in a tongue. What is it? Glossa, a language.
Whatever
the gift is


then, what is it? Could be demonic,
could be satanic.
I think it was in Corinth, in some cases,
could be that. Ecstatic speech is a part of many pagan religions in
Africa, East Africa. Tonga people of Africa, when a demon is exorcised,
sing in Zulu even though they say they don't know the Zulu language.
Ecstatic speech is found today among Muslims, Eskimos, Tibetan monks.
It's involved in para-psychological occult groups. Did you know that the
Mormons, even Joseph Smith himself advocates speaking in tongues? It
could be demonic.
Secondly, it could be learned behavior; you
just learn how to do it. If you can go to the Hunter's seminar, they'll
jump start you. It could be psychological. It could be a kind of a
self-induced hypnosis, a kind of a trance, where you just yield up all
of yourprovides 82 percent of all its electricity; and, with the backing of the Polish government , the conference is jointly sponsored by local coal companies, of the kind the UN wants to see driven out of business.

The Poles — as on immigration, as on the Davos elite -= are much more in tune with global trends than the UN delegates are. Around the world, coal is making a huge comeback because, unlike the renewables being championed by greens, it provides a cheap, reliable and effective source of energy.

In the United Kingdom, old coal stations are being paid over the odds to make up for the shortfalls caused by renewables.

According to the Telegraph:

Britain’s oldest coal-fired power plants prepared to fire up their hoppers for a price of almost £1,000


huge expansion project that will double the size — and the emissions — of the Kobe Power Plant. More than 14 million tons of carbon dioxide and other pollutants are expected to belch each year from the enlarged plant’s chimneys by 2022 — more than the entire CO2 emissions of the 1.5 million-strong city of Kobe. […] The Kobe project is one of more than 30 new power stations being planned or built by Japan that burn coal — the dirtiest and most polluting fossil fuel and one which is being phased out by some 30 governments around the world.

Australia, too, is on the brink of a new coal boom — largely to satisfy the growing demand in India, a heavy coal user.

Coal consumption grew by 1 percentQ:

Target css group of class or id?

I have a group of class name:
.hSpace5{padding-top:0.3125em;}
.hSpace10{padding-top:0.625em;}
.hSpace15{padding-top:0.9375em;}
.hSpace20{padding-top:1.25em;}
.hSpace25{padding-top:1.5625em;}
.hSpace30{padding-top:1.875em;}
.hSpace35{padding-top:2.1875em;}
.hSpace40{padding-top:2.5em;}

Is it possible to target all this class names by referring to the to the first few characters .hSapce--?

A:

you can do it like this  in css3
div[class^="hSpace"]

OR
div[class*="hSpace"]

Both are not similar but in your scenario both will work.
First is "starts with class name" and second is "contains class name".

A:

You can use the below selector to select all elements whose class attribute contains the value hspace. Note that this is a contains selector and hence the string can be present anywhere in the class name.
div[class*='hspace'] {
   /* styles */
}

div[class*='hspace'] {
  color: red;
}

aa

bb

ab

cd

cd

But check out for browser support.

As mentioned in Rab Nawaz's


the planetary sun gear 3. In this case the thrust bearing 6 comprises a thrust wear pad 8 forming an integral part of an oil-fill screw 9 mounted on the end cover 7. When the correct end float has been established by screwing in the oil-fill screw 9, an inner end of which also acts as the thrust pad 8, the oil-fill screw 9 is fixed in position by means of a locking nut 10. Another prior arrangement is shown in FIG. 2. A disadvantage of these known systems is that the correct adjustment may be lost for example when the oil-fill screw 9 is undone to check the hub oil level.
The present invention is directed towards overcoming these problems.the currency was concealed from the pricing markets.

In the fiat-gold systems of the past, steep price inflations always signaled that the official money was about to be destroyed and redenominated. This fear carried forward into our present purely symbolic currency system, but we soon evolved to accept price inflation as the cost of doing business. As long as it was low enough that we could out-gain it through other investments, the benefits that our fiat trading economy provided were readily accepted.

Over time we have grown numb to the slow, hidden increases of the inflation tax. In moderation, this tax would have been somewhat acceptable, in an immoral sort of way, as society stole the productivity and efficiency gains (from those that could provide such) to pay for itself.


of this tax is way, way above anything we imagine. Most of it hidden over many years in the "dollar reserve function".

As a credit-based currency expands, the market acts as the lever that balances equity values against the expanding currency within its legal tender zone. But in the case of the dollar, a constant outflow lasting decades has been absorbed and held in reserve (think reservoir) outside of the dollar zone.

In addition to this main monumental price deception, the little bit of price inflation that actually did seep into the dollar zone was either suppressed through the gold and oil price manipulation scheme, masked by CPI rigging, or simply papered over with low interest rates and intentional asset bubbles. In other words they handed out free money toa concept, a thought, an idea, a purely symbolic unit of account, and if the world decides it is not worth its weight, it will quickly hit the floor.

This part is important, because most people don't get it. The US dollar IS our debt to each other and to the world. The US dollar is backed by all the goods and services WITHIN the United States. Legal tender laws say it is so. The dollar currently buys many things outside of the United States, but there is no law that says it always will. The only law protecting dollar holders all over the world says that their dollars can be exchanged INSIDE the US. So when Ben Bernanke issued $500 billion in swaps to 14 different foreign central


as the world tries to make gold into something it isn't.

It is the mashing of the gold wealth concept with the circulating credit receipt concept that opens the door to some of the greatest problems man has ever seen. Take, for example, the period of the modern gold exchange standard. 1913: Creation of the Federal Reserve System. 1914: WWI. 1923: Weimar hyperinflation. 1930: The Great Depression. 1939: WWII. 1950: The Korean War. 1959: The Vietnam War. 1971: Off the gold exchange standard.

Inflation of the circulating money supply is simply a fact of life in our imperfect world. The collective or the King always finds a way to inflate or debase money to its own advantage. And if circulating money is gold, or based on gold, then inflation ishave just entered one of the rare short periods of rapid change. And in so doing, an unparalleled opportunity is presented to all commoners who would hold physical gold through the duration of this "punctuation". It is a de facto transfer of wealth that will rival some of the greatest windfall gains in history.

Imagine with me a three stage rocket which has just launched to take us to our next level of stasis and equilibrium. In the first stage of this ride, the fractional reserve paper market for gold will break up and all the existing gold demand will rush from paper into physical. These are the "gold bugs" that were fooled into paper promises. This stage represents a newfound equilibrium between already existing supply (physical gold) and


of equilibrium. Some things will remain the same while others will have changed forever. Here are just a few of the changes I imagine.

Gold will trade in physical form only. No longer will the owners of gold trust the custodianship of foreign nations.

Fiat currencies will still function in trade and as a unit of account, repositioned at their new values, wherever debt is required. But they will have to undergo a process of credibility re-establishment, much like a bankrupt individual, before they will ever again be used by people as a reliable store of value.

For producing individuals and nations alike, gold will become the wealth reserve of choice for the preservation of purchasing power earned through productive labor. Believe it or not, I think that our freshly neuteredelse in a growing economy.

In other words, money is priced in goods and labor. The price of money is goods or labor. You must either create them or surrender them for money.

Now, in our imperfect world, we can borrow without being productive with the money we borrow. We can borrow for pure consumption! But to do so we must pay the interest out of our own body. We must eat away at our own net capital to pay the vig if we choose not to be productive. Like a stranded starving hiker whose body begins to devour itself. Herein lies the fatal flaw in our system.

Fiat systems work the opposite of gold. While gold increases in value against the real goods that price it, fiat money supply grows


ird smallest value in -178/5, 2/7, 3, -1.1?
2/7
Which is the second smallest value?  (a) -0.2  (b) 5  (c) 3/4  (d) -10  (e) -30.6
d
Which is the second biggest value?  (a) -4  (b) -81  (c) -1/3
a
What is the second smallest value in 608/657, -2/5, -2/11?
-2/11
Which is the biggest value?  (a) 2  (b) 1/8  (c) -160  (d) -5  (e) -0.06
a
What is the third smallest value in 6, -146/11, 1/5?
6
Which is the second biggest value?  (a) 2/2781  (b) -2/17  (c) 0.04
a
What is the fourth smallest value in 0, 0.064, 10, -1?
10
What is the fourth smallest value in 2.8, -1, 3/4, -2/3?
2.8
Which is the fifth smallest value?  (a) -0.5  (b) -11  (c) -1/3 this.javaScript = javaScript;
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... Had [Wheeling] rested on the fact that public rights as defined by the plaintiffs, i.e. rights created under the plenary authority of congressional enactment, been involved, both the damages and the injunction would have been vulnerable. Thus the crucial distinction for separation-of-powers purposes is the character of the relief, not the character of the complaint.
Id. at 348 (internal citations omitted).
The court disagrees with the Benjamin court's holding for several reasons. First, the Supreme Court has recognized that the type of right involved in a case has meaning for separation of powers purposes. In Northern Pipeline Constr. Co. v. Marathon Pipe Line Co., 458 U.S. 50, 83-84, 102 S.Ct. 2858, 2877-78, 73 L.Ed.2d 598 (1982), the Court stated:
[There is] a critical difference between rights created by federalinroads into functions that have traditionally been performed by the Judiciary cannot be characterized merely as incidental extensions of Congress' power to define rights that it has created. Rather, such inroads suggest unwarranted encroachments upon the judicial power of the United States, which our Constitution reserved for Art. III courts.
Id. at 83-84, 102 S.Ct. at 2877-78.
Defendants contend that, because Northern Pipeline dealt with the power of Congress to grant Article III powers to legislative tribunals, and not with the power of Congress to reopen final judgments, it is irrelevant to the present case. The court disagrees. The above citation from Northern Pipeline speaks about the separation of powers, not only in the context of Congress's power to require persons to vindicate statutory rights before particularized tribunals, but also


rather simply to set aside the judgment and order a new trial or appeal." Id. at 219, 115 S.Ct. at 1453. Here, the legislative history of the PLRA clearly illustrates Congressional intent to set aside judgments made by "liberal federal judges" based on the populist sentiment that courts are mollycoddling prisoners. Regardless of the validity of such a sentiment, it provides no basis for violating the separation of powers. As the Plant court states, separation of powers is violated even if the legislature rescinds a final judgment "for the very best of reasons." Id. at 226-28, 115 S.Ct. at 1457.
Therefore, because the PLRA's termination provision (§ 3626(b)(2)) reopens final judgments and because it does not fall within the Wheeling exception, it is unconstitutional under separation of powers. Becausea constitutional violation that has been adjudicated. But we have no doubt that, to "save themselves the time, expense and inevitable risk of litigation," petitioners could settle the dispute over the proper remedy for the constitutional violations that had been found by undertaking to do more than the Constitution itself requires ..., but also more than what a court would have ordered absent the settlement.
502 U.S. at 389, 112 S.Ct. at 762-63 (citations omitted).
The CDC contends that the school desegregation cases are applicable since "the Supreme Court has indicated that its statements in [such] cases as to the appropriate nature and scope of equitable remedies are fully applicable to Eighth Amendment prison litigation." Specifically, CDC points to Lewis v. Casey, ___ U.S. ___, 116 S.Ct. 2174, 135 L.Ed.2d


(2002).; E. Collin et al., Phys. Rev. Lett. 93, 157005 (2004).

E. J. Griffith, C. D. Hill, J. F. Ralph, H. M. Wiseman and K. Jacobs, Phys. Rev. B **75**, 014511 (2007)

K. B. Cooper, M. Steffen, R. McDermott, R. W. Simmonds, S.Oh, D. A. Hite, D. P. Pappas, and J. M. Martinis, Phys. Rev. Lett. **93**, 180401 (2004).

Y. Nakamura, Y. A. Pashkin, and J. S. Tsai, Nature. **398**, 786 (1999).

Yu. A. Pashkin, T. Yamamoto, O. Astafiev, Y. Nakamura, D. V. Averin, T. Tilma, F. Nori and J. S. Tsai, Physica C **426–431** 1552 (2005).

Yu. A. Pashkin, T. Yamamoto, O. Astafiev, Y. Nakamura, D. V. Averin, J. S. Tsai, Nature **421**, 823 (2003).

O. Astafiev, Yu. A. Pashkin, Y. Nakamura, T. Yamamoto, and J. S. Tsai, Phys. Rev. B **74**, 094510Odontoameloblastoma: report of a case.
Ameloblastic odontoma is a mixed odontogenic tumor, which is characterized as being extremely rare, displaying aggressive clinical behavior, resembling a mixed radiopaque and radiolucent radiographic appearance and containing both ameloblastoma and a composite odontoma. An eleven-year-old boy complaining of the edentulous area at the anterior maxilla, was seen at the Department of Oral Surgery of Ege University Dental Faculty. The lesion presented a radiopaque and radiolucent features on panoramic radiogram. Locally operated lesion was diagnosed as ameloblastic odontoma, because it contains islands of ameloblastoma with calcified dental structures as odontoma. The patient was followed-up for 7 years and no recurrence was seen. This case is presented because of its rarity, early detection in an edentulous area of a child, and the successful choice of


The 64 candidates in the original field were all worthy members of Boston sports lore. The remaining 16 are the cream of the crop.

There were a few tight races in the second round, but each and every matchup in Round 3 should be epic.

Though all four top seeds advanced with ease into Round 3, the field is narrowing. Now, you’ll have Bill Belichick paired up with Carl Yastrzemski and John Havlicek going head-to-head with Ray Bourque, among others. Oh, and how’s this for greatness: Bobby Orr vs. Cy Young.

By the end of the week, the field of 64 will be down to just eight. Who gets there is up to you.Without this brane the 2d transverse space becomes a “semi-infinitely long pin” whose tip is identified as the origin of the coordinates. The NS-NS type $p$-brane (with negative tension) is necessary to spread out this pin-shaped space to get $R_2$ or $R_2/\mathbb{Z}_n$. In general codimension-1 brane solutions take completely different forms as compared with codimension-2 brane solutions, and the above correspondence between 5d models and $(p+3)$d models suggests that the role of the NS-branes in the background geometries may be much more significant than we expect.

0.5cm The consequence of the fact that the spacetime contains background NS-branes is crucial in the context of the cosmological constant problem. Consider a configuration that a D-brane is introduced on the background NS-brane, and SM-fields are living on that D-brane. In string


$\beta=\frac{4}{3}$) (8.4) simply becomes (4.5) as it should be. In this case $W(y)$ is not given by a power series of $l$. In the string theory limit ($b=k=4/3$, $\beta=1$), however, (8.4) becomes $$W(y) = 1-l\,e^{\sqrt{-\lambda}|y|}\,+\frac{1}{2}l^2 \, e^{2\sqrt{-\lambda}|y|}\,  + O(l^3) \,\,$$ upon taking $d^2_A d^{4/3}_\phi =1$, which shows that the change of $W(y)$ due to an introduction of the D-brane is only of an order $\sim g_s$.

Once $l$ is determined at the tree level, the effect of the higher order terms can be obtained by adding $\delta l$ to $l$, where $\delta l$ is the shift in $l$ due to the quantum correction (the terms with $n \geq 1$) to the D-brane tension. From (8.2) one finds that $\delta l$ is only of an order $\sim g^2_s$ :avoid this singular space is to introduce NS-NS type $p$-brane with negative tension on the orbifold fixed point. In general codimension-1 brane theory is entirely different from the codimension-2 brane theory, and the above correspondence between these two entirely different theories leads us to a conjecture that the whole flat backgrounds of the string-inspired brane world models (or the string theory itself) inherently involve the NS-branes implicitly in their ansatz.

As mentioned above, in the presence of the NS-branes the 5d spacetime becomes a direct product $M_4 \times S_1 / \mathbb{Z}_2$ with $\mathbb{Z}_2$-symmetry in the fifth compact dimension. The NS-branes contribute to fixing the background geometry of the 5d spacetime. After the geometry of the spacetime is fixed by the NS-branes we may also introduce D-branes on this background


\[hep-ph/9811323\].

Z. Kakushadze and S.-H. H. Tye, [*Brane World*]{}, Nucl.Phys. [**B548**]{}, 180 (1999) \[hep-th/9809147\].

R. Sundrum, [*Effective Field Theory for a Three-Brane Universe*]{}, Phys. Rev. [**D59**]{}, 085009 (1999) \[hep-th/9805471\].

G. Shiu and S.-H. H. Tye, [*TeV Scale Superstring and Extra Dimensions*]{}, Phys. Rev. [**D58**]{} (1998) 106007 \[hep-th/9805157\].

I. Antoniadis, N. Arkani-Hamed, S. Dimopoulos, and G. Dvali, [*New Dimensions at a Millimeter to a Fermi and Superstrings at a TeV*]{}, Phys. Lett. [**B436**]{}, 257 (1998) \[hepth/9804398\].

N. Arkani-Hamed, S. Dimopoulos and G. Dvali, [*The Hierarchy Problem and New Dimensions at a Millimeter* ]{}, Phys. Lett. [**B429**]{}, 263 (1998) \[hep-ph/9803315\].

E. K. Park and P. S. Kwon, [*A self-tuning mechanism in (3+p)d gravity-scalar theory*]{}, JHEP [**11**]{}, 051 (2007) \[hep-th/0702171\].

S. Ribault, [*D3-branes in NS5-brane backgrounds*]{}, JHEP [**02**]{}, 044 (2003) \[hep-th/0301092\].

S. Elitzur, A. Giveon, D. Kutasov, E. Rabinoviciclient = new DefaultHttpClient();

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                         0x00007fff91e083a1 -[NSCustomView initWithCoder:] + 652
25  Foundation                          0x00007fff96f29797 _decodeObjectBinary + 2860
26  Foundation                          0x00007fff96f2a976 -[NSKeyedUnarchiver _decodeArrayOfObjectsForKey:] + 1193
27  Foundation                          0x00007fff96f0145c -[NSArray(NSArray) initWithCoder:] + 486
28  Foundation                   0x00007fff91e083a1 -[NSCustomView initWithCoder:] + 652
60  Foundation                          0x00007fff96f29797 _decodeObjectBinary + 2860
61  Foundation                          0x00007fff96f2a976 -[NSKeyedUnarchiver _decodeArrayOfObjectsForKey:] + 1193
62  Foundation                          0x00007fff96f0145c -[NSArray(NSArray) initWithCoder:] + 486
63  Foundation


Ultrastructural analysis of the microfibrillar component of mouse and human periodontal oxytalan fibers.
Microfibrillar populations were quantified for mouse and human periodontal ligament oxytalan fibers in cross-section. Ten mouse fibers (Group 1) and ten human fibers (Group 2) were randomly selected from representative levels of the ligament and digitized for the total fiber area (TFA) and the microfibrillar component area (MFA). A third group of specific mouse oxytalan fibers (RER) was also evaluated. Quantified fiber dimensions varied markedly as did the percentage microfibrillar area for each group. Staining revealed morphologically different components within each fiber. Mouse and human microfibrils were composed of varying numbers of microfilaments. Analysis of covariance showed that the structural relationship between MFA and TFA was linear for each of the three groups. Slopes for thewishes. Neil

The 900 came with a cover which I leave on most of the time. It doesn't seem to change the weight but sometimes my hands just don't want to deal with it. When it travels it goes into a M Edge Touring sleeve.

The 600 didn't come with a case and I quickly learned to love the lightness compared to the 900. I have no plans to add any weight it since I'm loving holding it in one hand. I just recently bought the gold clutch case by case logic for travel. It could also double as an evening bag if the need ever arises.


for attorney's fees as set forth in the judgment from $750 to $400.
 [1] The general rule that a voluntary acceptance of the benefits of a judgment is a bar to the prosecution of an appeal therefrom "has no application where the benefits accepted are such that appellant is admittedly entitled to them or would not be affected or put in jeopardy by the appeal." (Schubert v. Reich, 36 Cal.2d 298 [223 P.2d 242].) [2] The court having found that appellant was entitled to a divorce on the ground of extreme cruelty was obliged under the law of this state to award her not less than one half of the community property. (Arnold v. Arnold, 76 Cal.App.2d 877 [174 P.2d 674].) [3] The partial record here presented, inpiano, organ
Ronald Brown - bass
Paul Humphrey - drums
Roy Brown - vocals

References

Category:Impulse! Records albums
Category:Albums produced by Bob Thiele
Category:Mel Brown (guitarist) albums
Category:1968 albums


[Categorizing variables in the statistical analysis of data: consequences for interpreting the results].
Frequently during the process of data analysis in epidemiological studies, the scale of one or more continuous variables is changed. The objective of this paper was to assess the consequences of categorizing variables during data analysis. We studied three situations with different scenarios for statistical analysis with regression models. The results show that dichotomizing continuous variables can substantially modify the relationships between dependent and independent variables. Thus, for example, in epidemiological studies trying to evaluate the effect of an exposure on a response, the magnitude and/or the direction of this effect can be biased by dichotomizing a variable. We therefore recommend avoiding, as much as possible, the categorization of variables when doing analyses.boiled or steamed), particularly Brussels sprouts and carrots; dessert consists of Christmas pudding (or plum pudding), sometimes mince pies, Christmas cake or trifle, with brandy butter or cream.

Italy

Italian regional traditions are varied. They are polarised in two areas: Northern Italy and Southern Italy (from Rome southwards). Moreover, often the Christmas Eve Supper is more important than the Christmas Dinner, because the Holy Mass is celebrated at midnight.

The primo is usually a kind of soup made with pasta (usually filled pasta, like tortellini) boiled in meat or capon broth. The secondo is very different in the two areas. In Northern Italy they usually eat poultry, often filled, or roasted or boiled and seasoned with sauces, like mostarda. In Southern Italy they eat the fried capitone eel, which is typical


                                     4
'134 Patent Fig. 7 ("FIG 7 is a view of the geodesic sphere created from the icosahedron of FIG
5(a) and showing the energized portion of the geodesic sphere array of a plurality of contiguous
subarrays that forms an electromagnetic beam along its broadside (zenith) direction towards a
vertex of the geodesic sphere .... "). In Figure 7, the electromagnetic beam is in the cellular
communication space 71 and would project out from the Figure directly toward the viewer. For a
geodesic sphere phased array antenna to provide coverage over an entire hemisphere - - from
horizonthis action pursuant to 28 U.S.C. § 1498(a),
which provides in relevant part:

       Whenever an invention described in and covered by a patent of the United States is
       used or manufactured by or for the United States without license of the owner
       thereof or lawful right to use or manufacture the same, the owner's remedy shall be
       by action against the United States in the United States Court of Federal Claims for
       the recovery of his reasonable and entire compensation for such use and
       manufacture.

28 U.S.C. § 1498(a) (2012). Because Plaintiff is the


                                        8
with a master's degree in electrical engineering, physics, or the equivalent, with at least eight years
of relevant work experience with phased atrny antennas, noting that additional relevant work
experience may substitute for formal education. Def.'s Br. 17. Plaintiff asserted that any
"competent antenna engineer" would be capable of understanding the term "sphere" in the '134
Patent. Pl.'s Br. 1 (ECF No. 137). The Court adopts the parties' substantially similar definitions
of a person of ordinary skill in the art to be a person with a master's degree in electrical
engineering, physics, or thethat it could be "ten (I 0% ), fifty percent (50%) or more up to even [one] hundred
percent (100%)" depending "on the specific applications ... for which the spherical phased array
antenna is built and utilized." Pl.'s Br. 2 (ECF No. 137). Defendant counters that the intrinsic and
extrinsic evidence regarding the '134 Patent limits the term "sphere" to structures that at·e "greater
than a hemisphere so as provide the phased atTay antenna with hemispherical or greater
communication coverage." Def.' s Br. 20.

        The Preambles to Claims 1, 14, 19, and 25 are Limiting

       Defendant argues that the preambles in independent Claims 1, 14, 19, and 25 which
describe the geodesic structure as a "sphere" limit all claims to "sphere"


"spherical" can encompass as little as 10% of a
sphere's surface. Id. Plaintiff, however, does not point to any claim language to support his
assertions.

         The ordinary and customary meaning of the term "sphere" readily connotes the shape of a
round ball. Phillips, 415 F.3d at 1314 ("In some cases, the ordinary meaning of claim language .
. . may be readily apparent even to lay judges, and claim construction in such cases involves little
more than the application of the widely accepted meaning of commonly understood words.");
Omega Eng'g, Inc. v. Raytek Corp., 334 F.3d 1314, 1323 (Fed. Cir. 2003) ("We indulge a heavy
presumption that claim terms carry their full ordinary and customary meaning, unless the patentee
unequivocally imparted a novel meaning to those terms oragreement [@pone.0068483-Blacker1]. Essentially, these statistics indicate the consistency with which a rat was classified as the same responder type over the 7 days, and how consistent each quads huddling time was across the 7 repeated exposures (see [@pone.0068483-Shrout1]). Consistency of responder type indicates their classification as active or passive remains stable across the repeated exposures, and consistency of huddling behavior indicates the amount of time a quad spends huddling remains consistent across the repeated exposures.

### 2.1.4. Post exposure test 1: Conditioned fear {#s2a4}

Three days after the final cat fur (or control) exposure, individual rats were returned to the same testing arena but with no fur present. A wooden hide box with a red Perspex lid (40×24×17 cm), identical to that used in the emergence test (see below), was


the no odor control rats \[hiding: *F*(1, 44) = 6.98, *p* = 0.011; latency to emerge: *F*(1,44) = 9.69, *p* = 0.003; distance travelled: *F*(1,44) = 33.13, *p*\<0.001\].

Conversely, there was no significant difference between active responders and the no odor control rats in the time spent hiding (*p* = 0.253), latency to emerge (*p* = 0.781) or distance travelled (*p* = 0.978). Compared to passive responders, active responders spent significantly less time hiding, took significantly less time to emerge from the hide box and travelled significantly more distance \[hiding: *F*(1,44) = 12.04, *p* = 0.001; latency to emerge: *F*(1,44) = 9.10, *p* = 0.004; distance travelled: *F*(1,44) = 14.71, *p*\<0.001\]. Neutral responders did not differ significantly from passive responders in time spent hiding, latency to emerge, or distance travelled (statistics not shown).

### 3.1.4. Post exposure test 2: Weak sucrose consumption (anhedonia) {#s3a4}

Results of the weak sucrose consumption test for anhedonia are shown in [Figure3.2.3. Behavioral responses to cat odor modulated by social exposure {#s3b3}

Rats exposed to cat fur spent significantly less time grooming and significantly more time immobile in the first 10 min of the session compared to rats that were not exposed to cat odor, \[Grooming: *F*(1,28) = 47.96, *p*\<0.001; Immobility: *F*(1,28) = 99.00, *p*\<0.001\]. However, the inhibition of grooming and increase in immobility in the presence of cat odor was significantly more pronounced for rats exposed alone than in a quad ([Fig 5A and 5B](#pone-0068483-g005){ref-type="fig"}), \[Grooming: *F*(1,28) = 4.67, *p* = 0.039; Immobility: *F*(1,28) = 16.28, *p*\<0.001\]. Furthermore, rats exposed to cat odor in a quad had a significantly greater number of contacts with the cat odor stimulus compared to rats exposed to cat odor alone ([Fig 5C](#pone-0068483-g005){ref-type="fig"}), *t*(14) = 2.23, *p* = 0.043. [File S3](#pone.0068483.s003){ref-type="supplementary-material"} is a representative video from Experiment 2


exposed to cat odor (bottom middle and right). However, rats exposed to cat odor alone (bottom middle) had significantly more activation than rats exposed to cat odor in a group (bottom right).](pone.0068483.g006){#pone-0068483-g006}

Finally, time rats exposed to cat odor in a quad spent in a huddle with three or four rats was significantly positively correlated with the number of c-Fos positive cells in the lateral part of the anterior olfactory nucleus (AOL) \[*N* = 7, *r* = .770, *p* = 0.043\], LSV \[*N* = 8, *r* = 0.713, *p* = 0.047\] and CPuM, *N* = 7 \[*r* = 0.926, *p*\<0.01\].

### 3.2.4. Differences between Active and Passive Responders {#s3b5}

None of the rats exposed to cat odor alone met criteria for being an active responder, with one rat being classified as neutral and the rest classified as passive. Conversely, 4 rats from the quads exposed to catactivated in rats exposed to cat odor when alone ([Table 1](#pone-0068483-t001){ref-type="table"}). Recent analyses suggest that the LHb may play a crucial role in suppressing locomotor activity when an aversive outcome is anticipated or when pain, stress or anxiety is experienced [@pone.0068483-Hikosaka1]--[@pone.0068483-Pobbe1]. Thus the LHb may drive some of the avoidance behaviour, and inhibition of locomotor activity observed during predator threat in the present study, and others (e.g. [@pone.0068483-PerrotSinal1], [@pone.0068483-Blanchard3]). This may be achieved through a gating influence on midbrain dopaminergic and serotoninergic systems as well as connections from the LHb to the DMPAG, which was also strongly activated in the present study, and again more strongly in rats exposed to cat fur when alone.

The PAG has an important role in controlling the behavioral and autonomic aspects of the


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{
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		sleep_time *= 2;
		if (sleep_time > NSEC_PER_MSEC)
			sleep_time = NSEC_PER_MSEC;

		if (intr && signal_pending(current))
			return -ERESTARTSYS;
	}

	__set_current_state(TASK_RUNNING);

	return timeout - t;
}

static int
nouveau_fence_wait_busy(struct nouveau_fence *fence, bool intr)
{
	int ret = 0;

	while (!nouveau_fence_done(fence)) {
		if (time_after_eq(jiffies, fence->timeout)) {
			ret = -EBUSY;
			break;
		}

		__set_current_state(intr ?
				    TASK_INTERRUPTIBLE:
				    TASK_UNINTERRUPTIBLE);

		if (intr && signal_pending(current)) {
			ret = -ERESTARTSYS;
			break;
		}
	}

	__set_current_state(TASK_RUNNING);
	return ret;
}

int
nouveau_fence_wait(struct nouveau_fence *fence, bool lazy, bool intr)
{
	long ret;

	if (!lazy)
		return nouveau_fence_wait_busy(fence, intr);

	ret = dma_fence_wait_timeout(&fence->base, intr, 15 * HZ);
	if (ret < 0)
		return ret;
	else if (!ret)
		return -EBUSY;
	else
		return 0;
}

int
nouveau_fence_sync(struct nouveau_bo *nvbo, struct nouveau_channel *chan, bool exclusive, bool intr)
{
	struct nouveau_fence_chan *fctx = chan->fence;
	struct dma_fence *fence;
	struct dma_resv *resv = nvbo->bo.base.resv;
	struct dma_resv_list *fobj;
	struct nouveau_fence *f;
	int ret = 0, i;

	if (!exclusive) {
		ret = dma_resv_reserve_shared(resv, 1);

		if (ret)
			return ret;
	}

	fobj = dma_resv_get_list(resv);
	fence = dma_resv_get_excl(resv);

	if (fence && (!exclusive || !fobj || !fobj->shared_count)) {
		struct nouveau_channel *prev = NULL;
		bool must_wait = true;

		f = nouveau_local_fence(fence, chan->drm);
		if (f) {
			rcu_read_lock();
			prev = rcu_dereference(f->channel);
			if (prev && (prev == chan || fctx->sync(f, prev, chan) == 0))
				must_wait = false;
			rcu_read_unlock();
		}

		if (must_wait)
			ret = dma_fence_wait(fence, intr);

		return ret;
	}

	if (!exclusive || !fobj)
		return ret;

	for (i = 0; i < fobj->shared_count && !ret; ++i) {
		struct


Q:

Running Makefile continuously gives `No rule to make target` error

I'm new to using makefiles for my projects, and I decided to start since I got tired of writing out all of the commands and arguments.
The current makefile that I have looks like this:
run_program:
        CUDA_VISIBLE_DEVICES=1
        python DIR/main.py --setup2

When I run this program using the following command:
make run_program

I get the following error:
make: *** No rule to make target 'run_program'.  Stop

I've made sure that the makefile is in the appropriate directory and that there are no spelling errors of the sort, but I'm having trouble figuring out what I did wrong. I've checked others answers such as gcc makefile error: “No rule to make target …”as fail safe as
Dropbox. If something does get corrupted its really simple to go back in the
version history. I can't remember the last time I had a file system corruption
with ext3, I suppose they still happen, but not to me in solid use for years.
Obviously my mercurial repository is also backed up regularly.

I don't agree that a backup system has to be restore tested periodically,
instead I believe that the restore process has to be an integral part of the
workflow. In my scenario, I rsync to hg, commit and push, then from other
machines in my workflow (or more likely vm instances) I pull+rsync back. This
way the backup and restore cycles are just part if the workflow and everything
is version controlled at the same time.

------
duncans
If you're on windows the following


      (for /r C:\Users\username\Dropbox %%F in (*.*) do (if %%~zF LSS 1 echo %%F)) > C:\Temp\emptyfiles.txt

------
piyush_soni
Dropbox has lost my files as well. I had kept some very important private
files there which I just wanted to keep there without the need of updating
them/syncing them. After uploading, I removed the local copy of that private
top level folder, as I didn't want to keep a local copy in my computer. With
the next sync, this STUPID SH*T removed the folder from their server as well,
without any warning of any sort! Any system which deletes the files without
asking, should just not be used or depended on.

~~~
djrogers
It sounds like you don't quite understand how Dropbox is supposed to work - it
replicates whatever you have locally to the clouddisk. And then you have poor old taste, which is like barely the throughput of a pocket calculator. And [then the] naught .7 percent, that's the amount we're actually aware of. So a lot of your vision – the bulk of it is visual, and it's pouring in – it's unconscious."

What this means for visual consistency – aside from reinforcing its importance – is that even minor lapses in consistency can be picked up by the user without them being aware.

Maintaining this consistency, then, is more important that it may seem… and this article will explain why.

Familiarity

Because so much of visual design affects the user on a subconscious level, your site must first feel familiar. When users encounter a new design, they are armed only with their prior


trip of a lifetime to Nepal (so really if you think about it, this wouldn’t be possible unless she introduced me to all things magical aboutChildreach!). Having a best friend like Caitlin is in itself, a whole other essay of a post. Anyways, back to topic. Caitlin went to Nepal to help build the Meera Centre, a specialist early childhood development centre that provides services to the community and a safe nurturing environment for children. Childreach work and effort to help children is truly an inspiration. This is why I decided to do it forChildreach, after researching a bit more and knowing the work Caitlin had done from updates etc, I knew that this was the charity I felt strongest about.

I wanted to make a difference in someoneslife, even if it was just one life I could touch, that is all that mattered to me.

Some people can be so hateful and shameful over people who do these things for charities, when the reality is.. would I be able to raise such a vast amount of money if there wasn’t a challenge in place? No! So to the people who perceive risking my life and climbing up the highest free-standing mountain in the world a holiday paid for you could never be so wrong!

A view into Moshi from above.

So with the sky dive in mind and University just starting, September slipped away super fast. University life was treating me well and I began to feel like I wanted a bit more out of University life. Societies


IF ALL MY BODY ACHES AT THE END OF THIS, I HAVE A BEACH TO LIE ON FOR A WEEK AFTER KILIMANJARO!

Guys, wish me all the luck in the world for my climb and if you want to help me in any ways, donations to my cause and more info on my climb can be found here. I will be making Kilimanjaro into a travel series, to keep updates on what has been happening etc, so keep a big eye out for those (there will be a few!).list.Count)
           return false;

       var element = list[index];
       var type = typeof (T);
       if (Nullable.GetUnderlyingType(type) != null)
       {
           if (element is bool?)
               return (element as bool?).Value;
           return element != null;
       }

       var defaultValue = default(T);
       // Use default(T) to actually get a value


466 So.2d 99 (1985)
ALABAMA POWER COMPANY
v.
Helen Earnest CUMMINGS, et al.
83-745.
Supreme Court of Alabama.
February 15, 1985.
*100 James A. Bradford of Balch, Bingham, Baker, Ward, Smith, Bowman & Thagard, Birmingham, and Edward R. Jackson of Tweedy, Jackson & Beech, Jasper, for appellant.
Jack Drake and Joseph G. Pierce of Drake, Knowles & Pierce, Tuscaloosa, for appellees.
FAULKNER, Justice.
Helen Cummings brought this action against Alabama Power Company for damages to her property allegedly caused by the collapse of an underground coal mine owned by the defendant. A jury awarded Cummings $35,000.00 in damages. Alabama Power Company appeals. We affirm.
Cummings's home sits above the Gorgas Mine, America # 3, in Walker County, Alabama. The mine is located 240 feet below the surface and was last worked in 1948. In May of 1979, Cummings firstvalue of the property. Alabama Power argues that Cummings's opinion as to the value of the property was based only on the current selling prices of other houses. Therefore, it argues that she had no experience enabling her to know the value of the property and that its objections to her testimony should have been sustained.
The record does not support the power company's contention. The record shows that Cummings testified that in her opinion her house was worth $60,000.00 before the house began to fall apart and that it was worth $1,000.00 afterwards. This constituted before and after value. The general rule is that the owner of real estate is competent to testify as to its *103 value. Roberson v. McCarley, 259 Ala. 583, 585, 67 So.2d 814,


was changed to 1∶1 DMEM/Ham\'s F12 (including antibiotics described above) with 2% Ultroser G serum substitute (BioSerpa S.A., Cergy-Saint-Christophe, France). Once the cells had reached confluence (typically following 2 days of culturing on the membrane) the media was removed from the upper chamber to expose the apical surface to air and establish the ALI (referred to as ALI "day 0"). The cells were then grown at 37°C, 8% CO~2~, and the culture medium was changed every other day. Following 5 days on ALI, the cells were grown at 37°C, 5% CO~2~ until harvested.

To assess cell differentiation, the ALI membranes were processed for immunofluorescence with an anti-cytokeratin 5 and anti-β-tubulin IV antibody and scanning electron microscopy. For immunofluorescence the samples were processed by two methods. For whole membrane analysis,Integrity Number (RIN) \>7.0; (2) 3′/5′ ratio for GAPDH \<3; and (3) scaling factor \<10.0 [@pone.0018378-Raman1]. All MIAME-compliant raw data have been deposited in the Gene Expression Omnibus (GEO) site (<http://www.ncbi.nlm.nih.gov/geo>), curated by the National Center for Bioinformatics. Accession number for the data is GSE24337.

Analysis and Statistics {#s2e}
-----------------------

For microarrays passing QC, the expression levels for all probe sets were extracted using GeneSpring 11 after normalization by array only rejecting those probes that were not expressed in any sample (No Affymetrix "P" call). Significant gene expression differences between the basal cells and differentiated epithelium were determined with Benjamini-Hochberg correction for multiple testing [@pone.0018378-Benjamini1]. Unsupervised hierarchical cluster analysis of the normalized expression levels of the differentiated epithelium and basal cell cultures was done using GeneSpring GX 7.3. Two independent sets


a clear group of genes overexpressed in basal cells relative to differentiated epithelium, and another group of genes underexpressed in basal cells relative to differentiated epithelium ([Figure 2B](#pone-0018378-g002){ref-type="fig"}). Clustering with another independent set of 1,000 randomly picked genes gave a very similar pattern (not shown). A volcano plot revealed a large number of probe sets significantly (p\<0.01) overexpressed (basal/differentiated epithelium ratio \>5) or underexpressed (basal/differentiated epithelium ratio \<0.2) in the basal cells compared to the differentiated epithelium ([Figure 2C](#pone-0018378-g002){ref-type="fig"}). This cut off is based on the knowledge that the differentiated human airway epithelium contains ∼20% basal cells [@pone.0018378-Heguy1], [@pone.0018378-Boers1]--[@pone.0018378-Hackett2], i.e, we expect a basal cell-enriched gene to have a basal cell/differentiated epithelium expression ratio of \>5. The subset of genes up-regulated in basal cells, as compared to the6A, 6B, 7, 16, 17 and 34 with basal/differentiated epithelium expression ratios between 7.8 and 667. Of the classic basal-specific cytokeratins, KRT5 and KRT14, KRT5 was in the human airway basal cell signature (expression ratio 8.6). Although KRT14 was up-regulated in basal cells as compared to the complete differentiated airway epithelium (expression ratio 203), the borderline significance (p = 0.016) precluded it from inclusion in the human airway basal cell signature.

10.1371/journal.pone.0018378.t005

###### Extracellular Matrix and Cytoplasmic Structural Proteins in the Human Airway Basal Cell-enriched Signature.[1](#nt112){ref-type="table-fn"}

![](pone.0018378.t005){#pone-0018378-t005-5}

  Category                        Genes    Mean expression in differentiated epithelium   Mean expression in basal cells   Basal/differentiated epithelium expression


in the proliferating cell compartments of various epithelia [@pone.0018378-Moll1], [@pone.0018378-Leigh1], [@pone.0018378-Schermer1], were the top human airway basal cell signature genes but were not present among the mouse basal cell-enriched genes.

Basal Cell -- Extracellular Matrix Relationships {#s4b}
------------------------------------------------

Functional analysis of the human airway basal cell signature using a diverse set of analytic tools identified a number of gene categories relevant to function of the cells to maintain the structural integrity of the airway epithelium. Consistent with their role in establishing contacts with the various extracellular components as well as between airway epithelial cells [@pone.0018378-Evans1], the human airway basal cell signature was enriched in functional categories related to the extracellular matrix-receptor interactions and cell-cell communications. Included in this category were biological functions relevant to anchorage of the epithelium to the extracellularfor basal cells based on immunohistochemical analysis [@pone.0018378-Hicks1]. Although the relevance of ITGA5 and ITGB6 to airway basal cell biology is largely unknown, several independent lines of evidence indicate their potential relevance to the stem/progenitor cell and tissue repair functions of airway basal cells. ITGA5 mediates fibronectin-dependent epithelial cell proliferation through activation of EGFR [@pone.0018378-Matsuo2], activates a NF-κB-dependent transcriptional program regulating angiogenesis [@pone.0018378-Urbinati1], and promotes cell migration in a HIF1α-dependent manner [@pone.0018378-Ryu1]. Consistent with this data, genes encoding elements of the EFGR and NF-κB signaling pathways, functional categories related to cell proliferation, migration and angiogenesis, as well as transcriptional factor HIF1α, were enriched in the human airway basal cell signature. Integrin alpha 5 beta 6, encoded by the ITGA5 and ITGB6 subunit genes, is required for spacially-restricted activation


to International Trade Administration.]

                                          Decided:   May 20, 2004

     Cameron & Hornbostel LLP (Dennis James, Jr.) for the
plaintiffs.

     Peter D. Keisler, Assistant Attorney General; David M. Cohen,
Director, Commercial Litigation Branch, Civil Division, U.S.
Department of Justice (Lucius B. Lau); and Office of Chief Counsel
for Import Administration, U.S. Department of Commerce (Robert E.
Nielsen), of counsel, for the defendant.

           AQUILINO, Judge:   This case commenced pursuant to 19

U.S.C. §§ 1516a(a)(2)(A)(i)(I)       Page 3

tiffs have filed a motion for judgment upon the ITA record pursuant

to USCIT Rule 56.2.

                                I

          All of this litigation, of course, has grown out of

Certain Iron Metal Castings From India: Countervailing Duty Order,

45 Fed.Reg. 68,650 (Oct. 16, 1980).   And, as indicated, this par-

ticular consolidated case focuses on the final results of an ITA
review of imports subject to that order for the calendar year 1997.

Plaintiffs' motion faults those results as follows:

     A.


351 (1998), unless otherwise
     indicated. Because the request for this administrative
     review was filed before January 1, 1999, the Department's
     substantive countervailing regulations, which were
     published in the Federal Register on November 25, 1998
     (see CVD Regulations, 63 FR 65348), do not govern this
     review.

65 Fed.Reg. at 31,515-16 (bold face in original);

     . . . [U]nless otherwise indicated, all citations to the
     Department's regulations are to the regulations as
     codified at 19 CFR Part 351 (1998).

64 Fed.Reg. at 61,593;
Consolidated
Court No. 00-06-00280           relied on both subsections (5)(D) and (5)

(E) in deriving the benefit conferred.     Its Preliminary Results

state that the amount of customs which should have been paid by the

company to import the goods constitutes the benefit under (5)(E) of

the Act. 64 Fed.Reg at 61,596-97.    At the beginning, the decision

memorandum assures that there were no changes in methodology from

that used in the Preliminary Results.    The agency's Final Results

are to the same effect.   See 65 Fed.Reg. at 31,515.   To the extent

the record induces a conflicting inference, "the court will uphold

a decision of less-than-ideal clarity if the agency's path may be

reasonably discerned". Neenah Foundry Co. v. United States, 25 CIT

   ,      ,


face5, is

actually apposite.

             Indeed, the ITA's reasoning in this matter, quoted above,

makes no mention of that section.         Rather, its "essence" is that

"the overdue loan becomes a new loan with a new applicable interest

rate."     Nothing on the record, however, supports this thesis, nor

should any support be found, given that the loan(s) at issue con-

sisted of a sum certain of money receivable within a specified

period of time at a particular rate of interest or thereafter at a

greater rate.       Those were the elements of the borrowing, the

      5
        this order, the Department has
     found the section 80HHC tax deduction program to be an
     "untied" export subsidy program. The benefits provided
     under this program are not tied to the production or sale
     of a particular product or products. It is the Depart-
     ment's consistent and long-standing practice to attribute
     a benefit from an export subsidy that is not tied to a
     particular product or market to all products exported by
Consolidated
Court No. 00-06-00280


Members of the Shan State Progress Party and Shan State Army-North meet for their fourth congress at party headquarters in Wanhai in Kyethi township, eastern Myanmar’s Shan state, Nov. 28-Dec. 2, 2018.

RFA

An ethnic Shan political organization has called for dialogue to bring about a cease-fire between opposing Shan armies in beleaguered eastern Myanmar, in an attempt to stop the fighting and advance the country's faltering peace process.

The Shan State Progress Party (SSPP), whose armed wing, the Shan State Army-North (SSA-N), is one of the state’s ethnic insurgent groups, issued the call in a statement the party released at the end of a five-day congress at its headquarters in the town of Wanhai in northern Shan state's Kyethi township. Nearly 340 SSPP members attended the meeting.

The SSPP said itwith government ministries and the military on regional security and operations,” he said. “I assume that the armed group shot us because it had a grudge.”

Muse township administrator Thu Rein said the military, and not local police, will handle the case.

“Our department will work together with the military as needed,” he said. “We have deployed military and police around town, but it’s impossible to cover all places.”

Reported by Kan Thar, Tin Aung Khine, and That Su Aung for RFA’s Myanmar Service. Translated by Khet Mar. Written in English by Roseanne Gerin.


hard labor. The court ordered that all three sentences be served concurrently with each other.
On March 20, 2007, the State filed a habitual offender bill of information alleging the defendant was a second felony offender. On the same day the defendant waived his rights and entered an admission to the allegations in the habitual offender bill. The court vacated the defendant's sentence as to Count 2. In accordance with a sentencing agreement, the court imposed an enhanced sentence of 15 years on Count 2, to run concurrently with the sentences on Counts 1 and 3 and with any other sentences the defendant was serving.
The defendant now appeals under Crosby, supra.
FACTS
These facts are taken from the transcript of the defendant's suppression hearing, as well as from the transcript ofthe Jefferson Parish Sheriffs Office was there. A woman answered the door and identified herself as Patrice New. Detective Shane Klein testified he immediately smelled the odor of burning marijuana.
Relying on the attachments on Patrice New and the smell of marijuana, the officers stepped inside the apartment. Klein testified that Patrice New was immediately arrested on the attachments. Gerdes and Klein saw the defendant running up the staircase that led to the second floor of the apartment. Klein said he and Gerdes followed the defendant, and they stopped him as he walked out of a bathroom on the second floor. Klein testified he did not see what the defendant had been doing in the bathroom, but he saw water around the toilet. Klein said that based on the


of Patrice New's apartment before the search warrant was signed. He challenges only the seizure of the evidence taken in connection with the search warrant, including the narcotics evidence found inside of the toilet.
The Fourth Amendment to the United States Constitution and Article 1, § 5 of the Louisiana Constitution prohibit unreasonable searches and seizures. State v. Boss, 04-457, p. 5 (La.App. 5 Cir. 10/26/04), 887 So.2d 581, 585. If evidence is derived from an unreasonable search or seizure, the proper remedy is to exclude the evidence from trial. Id. Warrantless searches and seizures are unreasonable per se unless justified by one of the exceptions to the warrant requirement. State v. Thompson, 02-0333, p. 6 (La.4/9/03), 842 So.2d 330, 335-36. The State bears the burden of proving thethings like that."
Klein said that occurred after the search warrant was issued. Klein also stated that, aside from the marijuana in plain view and the items found on the defendant's person in the search incident to arrest, nothing was seized prior to issuance of the search warrant. Klein testified he was present when the toilet was broken and the narcotics were found inside of it.
Dufrene testified that Klein notified Gerdes by radio once the search warrant had been signed.
We conclude that the officers who remained at the apartment began the search after they received the radioed communication from Klein that the judge had signed the warrant, but before Dufrene and Klein returned to the scene with the warrant.
The Fourth Amendment does not require that the accused be served


Does the Arthroscopic Latarjet Procedure Effectively Correct "Off-Track" Hill-Sachs Lesions?
The glenoid track concept describes the dynamic interaction of bipolar bone loss in anterior glenohumeral instability. Initial studies have successfully demonstrated this concept's application in clinical populations. In clinical practice, the Latarjet procedure is commonly the preferred treatment in addressing "off-track" Hill-Sachs lesions. The effectiveness of this procedure in restoring such lesions to an "on-track" state, however, has not yet been evaluated or described in the literature. The Latarjet procedure would transform "off-track" Hill-Sachs lesions to "on-track" lesions. Lesions would remain "on-track" during follow-up, despite glenoid remodeling. Case series; Level of evidence, 4. Patients with "off-track" Hill-Sachs lesions treated with the arthroscopic Latarjet procedure between March 2013 and May 2014 were included. Glenoid track and coracoid graft contact surfaceLast Wednesday, we started our deep dive into PowerShell. This week, we continue our exploration of Inline .NET code when scripting. This trick allows you to extend PowerShell and to create custom commands for your environment. If you are interested in other techniques like this, pick up a copy of PowerShell Deep Dives and start really exploring PowerShell!

Today’s tutorial focuses on creating a .NET class. This section was written by Richard Siddaway:

At this point you may be thinking that you can combine the two outputs into a single object. There are a number of ways of performing this task. Using New-Object to create a custom object is the most commonly used, but there’s an alternative: create and compile a .NET class as part of your script. This class


becomes part of the .NET framework loaded into PowerShell and can be accessed and used like any other class. It may seem that this is an additional complication you don’t need—and in many cases, you would be correct. But using this technique offers some benefits:

Class properties are strongly typed.

The class has a unique name, which means it works easily with PowerShell’s format and type files.

Strongly typed is a way of saying that the value you pass to a property must be of the correct data type or be automatically convertible to the correct data type. If you define a property as an integer and try to pass it a string value, PowerShell attempts to convert the string to an integer. If the conversion works, everything is fine andthe appropriate compiler installed on your system.

NOTE You can’t unload a type or change it once you’ve successfully compiled the code. You have to change the type (class) name or start a new instance of PowerShell.

The code now reverts to the PowerShell you know and love. A function is defined (#3) with one parameter: a computer name that can be supplied by parameter or through the pipeline. Test-Connection is used as part of the validation process to ensure that the computer is reachable.

Calls to Get-CimInstance retrieve the operating system data (#4) and the computer hardware information (#5). You could substitute Get-WmiObject for Get-CimInstance, although I recommend moving to the CIM cmdlets for new work.

A hash table is used to create the property set (#6). Together with New-Object (#7)


Committee. “This amendment simply sets in stone what the framers of the Constitution already implied and intended all along.”

While opponents dismissed such historical interpretations, Attorney General Aaron Frey seemed to question the need for a constitutional amendment because he said state law already reserves voting rights for citizens.

“This means that municipalities are not currently able to adopt ordinances to allow non-citizens to vote in municipal elections, as these ordinances would violate the statutes,” Frey wrote in a letter to committee members.

Last year, Portland Mayor Ethan Strimling and Councilor Pious Ali co-sponsored a proposal to allow legally present non-citizens to cast ballots for City Council, school board and other city elections. The Portland City Council voted in August to send the issue to a council committee for additional workthe 20th century that we began stopping immigrants from having the right to vote.”

Portland has, for years, been a destination for immigrants fleeing war, persecution and economic strife in their native countries. The city is home to a vibrant community of immigrants in a state whose population consistently ranks among the whitest – and oldest – in the country. Yet the influx of asylum-seeking immigrants from sub-Saharan countries – most of whom arrive in the U.S. legally with visas – in recent years has strained the city’s social service programs and drawn national scrutiny from conservatives amid the polarized debate over immigration.

Strimling said other cities around the country already allow non-citizens to vote in local elections because immigrants are active – and important – members of those communities.

“You


< i \le n$, and $a_{n+1}<0$.

Let $D_i$ be the prime divisors on $X$ corresponding to the vertices $v_i$, and $E_i = \phi(D_i)$ for $1 \le i \le n$ their images on $Y$. $D=D_{n+1}$ is the exceptional divisor of $\phi$, and the restricted morphism $\bar{\phi}: D \to F = \phi(D)$ is a toric Mori fiber space. Let $\mathcal{D}_i$ and $\mathcal{E}_i$ respectively be the prime divisors on $\mathcal{X}$ and $\mathcal{Y}$ above $D_i$ and $E_i$.

We write $B\vert_{\phi^{-1}(U)} =\sum_{i=1}^{n+1}\frac{r_i-1}{r_i}D_i$, and $C\vert_U = \sum_{i=1}^n\frac{r_i-1}{r_i}E_i$. The assumption that $K_X+B$ is positive for $\phi$ is expressed by the following inequality $$\sum_{i=1}^{n+1} \frac{a_i}{r_i} < 0.$$

The following Lemma \[2\] is [@log; @crepant] Theorem 4.2 (4):

\[2\] Let $\mathcal{W}=(\mathcal{X} \times_Y \mathcal{Y})\tilde{}$ be the normalized fiber product, and let $\mu$ and $\nu$ be the projections. Then the functor $\Phi = \nu_*\mu^*: D^b(\text{Coh}(\mathcal{X}))$$- \sum_{i=1}^{\alpha} \frac{a_i}{r_i} < \sum_{i=1}^{n+1} \frac{a_ik_i}{r_i}
\le 0$$ for some integers $k_{n+1}$. On the other hand, for an arbitrary sequence of integers $(k_1,\dots,k_n)$, there exists an integer $k_{n+1}$ such that $$- \sum_{i=1}^{\alpha} \frac{a_i}{r_i} <
\sum_{i=1}^{n+1} \frac{a_ik_i}{r_i} \le
- \sum_{i=1}^{n+1} \frac{a_i}{r_i}.$$ The difference of the above two intervals is covered by the consideration on the Koszul resolution of the sheaf $j_{F,2*}j_{F,1}^*\mathcal{O}_{\mathcal{F}}$. Indeed assume that $k=(k_1,\dots,k_{n+1})$ is a sequence of integers such that $$0 < \sum_{i=1}^{n+1} \frac{a_ik_i}{r_i} \le
- \sum_{i=1}^{n+1} \frac{a_i}{r_i}.$$ If $T$ contains all the invertible sheaves of the form $$\mathcal{O}_{\mathcal{Y}}(\sum_{i=1}^n l_i \mathcal{E}_i)$$ such that $l_i = k_i$ or $k_i - 1$, $l_{n+1}=k_{n+1}$ and that $\sum_{i=1}^n l_i < \sum_{i=1}^n k_i$, then $T$ also contains $\mathcal{O}_{\mathcal{Y}}(\sum_{i=1}^n k_i \mathcal{E}_i)$, because $D^b(\text{Coh}(\mathcal{F}))_k$ is contained in $T$. Therefore by the induction on $\sum_{i=1}^{n+1}


and salt in a medium bowl. Whisk together. Fold dry ingredients into wet until just combined. Form dough into a ball and refrigerate for at least 30 minutes for ease of rolling (optional, but highly recommended; you can also pop it in the freezer for 5-10 minutes if you’re short on time). Roll out dough and cut with cookie cutters as desired. Place shapes on a lined baking sheet. For non-shaped cookies, you can also roll dough into balls, sprinkle with raw sugar, and place onto a lined baking sheet. Bake 8-10 minutes until just golden. Allow to cool before eating or icing. Enjoy! PS – If you want more gingerbread goodness, try this yummy Nutty Gingerbread Granola!

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depleted of inositol for 3 days at 30°C.](1471-2091-8-16-1){#F1}

To determine if the components of the SAGA or SLIK complex influence the truncation of Spt7, we introduced *YCpDed-TAP-Flag-SPT7*into yeast strain BY4741 (wild-type) and isogenic strains deleted for *GCN5*, *RTG2*, *SPT8, UBP8, ADA1*and *SPT20*. Cells were grown in YPD media and protein extracts examined for Spt7 by Western blotting with anti-Flag antibody (Figure [2a](#F2){ref-type="fig"}). Two proteins with apparent molecular masses of approximately 220 and 200 kDa were present in wild-type cells containing *YCpDed-TAP-Flag-SPT7*but not in control cells (compare lanes 1 and 2). The size of these molecules suggest that they represent the TAP-Flag tagged full-length (Spt7~SAGA~) and SLIK-forms (Spt7~SLIK~) of Spt7. The ratio of SAGA:SLIK forms of Spt7 was \~3:1 in the wild-type strain BY4741 (lane 2). This relative amount of


the absence of Sgf11 \[[@B40]\]. Nonetheless, while not eliminating other mechanisms, the result is consistent with a model whereby binding of Ubp8 to SAGA may alter the accessibility of the C-terminus of Spt7 to cleavage. Interestingly, another Flag-antibody reactive band, Spt7~Form3~, was evident in the sample lanes but not in the control. Since Spt7~Form3~was somewhat obscured by a Flag antibody cross-reactive band, we analyzed the Spt7 forms in different strain backgrounds after first purifying TAP-Flag-Spt7 on IgG-agarose (Figure [2c](#F2){ref-type="fig"}). After purification a Flag-reactive molecule with an apparent mass approximately 20 kDa less than Spt7~SLIK~(also see Figure [3b](#F3){ref-type="fig"}) was revealed. The observed difference in mass of this molecule relative to intact Spt7 estimates an end-point at approximately amino acid residue 950. As was the case for Spt7~SLIK~, the levelTAP-purification.

Conclusion
==========

In this report we show that processing of the C-terminus of Spt7 to the form found in the SLIK complex and to a novel third form does not require a functional SAGA complex. C-terminal truncation occurs in the absence of key components of SAGA and SLIK complexes. Spt20 and Ada1 are necessary for the integrity of a complete SAGA complex with their deletion resulting in severe transcriptional effects \[[@B6],[@B22]\], yet processing occurs in their absence. In addition, since the truncated Spt7 molecules were present in a *gcn5Δ0*strain, histone acetylation is not required for processing. Also suggesting that processing of Spt7 is independent of the function of SAGA, we found that a truncated derivative of Spt7 that lacks the histone fold is capable of being processed in a strain


Spt7.

Methods
=======

Yeast strains
-------------

The wild-type yeast strains BY4741 (*MATa hisΔ0 leu2Δ0 met1Δ0 ura3Δ0*) and BY4742 (*MATα hisΔ0 leu2Δ0 lys2Δ0 ura3Δ0*) and the consortium constructed isogenic knockout strains \[[@B45]\] BY3218 (*spt7Δ0*), BY10809 (*ubp8Δ0*), BY17285 (*gcn5Δ0*), BY14619 (*rtg2Δ0*), BY12666 (*spt8Δ0*), BY14433 (*sgf73Δ0*), BY13418 (*sgf29Δ0*), BY2781 (*sgf11Δ0*), BY1038 (*ada1Δ0*) and BY17390 (*spt20Δ0*), and strains containing C-terminally TAP-tagged SAGA components were purchased from Open Biosystems or Research Genetics. CY1811 is a derivative of BY4741 that contains a *YIplac211-GAL-Flag*~3~*-SPT7*integrated at the endogenous locus.

DNA constructs
--------------

*YCpDed-TAP*is a derivative of the *LEU2*containing centromeric plasmid YCplac111 \[[@B46]\] that contains a *DED1*promoter \[[@B9]\] driving expression of a TAP epitope. The *DED1*promoter was synthesized by PCR using oligonucleotides 4149-1 and 4149-2 (see Table [1](#T1){ref-type="table"}) and cloned as a *Pst*I-*Bam*HI fragment into YCplac111. The TAP epitope was subsequently cloned as a *Bam*HIto thank Amy Tong and Drs. Brenda Andrews, Charlie Boone and Kathleen Gould for providing reagents as well as David Canton, David Litchfield, Meagan Davey, David Edgell, Kerri Kobryn and David Haniford for their discussions on this manuscript. This work was supported by a Canadian Institutes of Health Research operating grant to CB. SH is supported by a NSERC studentship, GL and AM by Western Graduate Research Scholarships.


and humidity at 55--60%. Mice were randomly split in three groups (*n* = 11/group), and dietary interventions started after 1 week of acclimatization to the facility, i.e., at 3 months of age. During 6 months, mice were fed standardized diets containing 10%, 45%, or 60% of kilocalories from lard-based fat (D12450B, D12451, D12492, Research Diets, New Brunswick, NJ, United States), as previously detailed ([@B56]). Food and tap water were provided *ad libitum*. After this 6-month housing period, the following procedures were carried out sequentially with 2 days of interval: behavior experiments, one MRS scan session, glucose tolerance tests, tissue collection.

Behavioral Tasks
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Exploratory behavior and locomotor activity of mice was evaluated over a 5-min period in the dark, using a squared open field arena measuring 30 cm × 30 cmtime of 2.8 ms and repetition time of 4 s ([@B43]). We accumulated 210, 320, and 400 scans for the cortex, hippocampus, and hypothalamus, respectively. The order of scanning the regions was random.

The concentrations of brain metabolites were determined with LCModel (Stephen Provencher Inc., Oakville, ON, Canada), including a Mac spectrum in the database and using the unsuppressed water signal measured from the same VOI as internal reference ([@B21]). The following metabolites were included in the analysis: alanine, ascorbate, aspartate, creatine, γ-aminobutyrate (GABA), glutamine, glutamate, glutathione, glycine, glycerophosphorylcholine, glucose, lactate, *myo*-inositol, *N*-acetylaspartate, *N*-acetylaspartylglutamate (NAAG), phosphorylethanolamine, phosphorylcholine, phosphocreatine, *scyllo*-inositol, taurine. The Cramér-Rao lower bound (CRLB) was provided by LCModel as a measure of the reliability of the quantification for each metabolite. In most measured spectra, *scyllo*-inositol was below the


a glycemia that was proportional to the amount of fat in the diet (*F* = 23.1; *P* \< 0.001, Figure [1C](#F1){ref-type="fig"}), while insulinemia was similarly increased in both HFD groups compared to controls (*F* = 9.2, *P* \< 0.001, Figure [1D](#F1){ref-type="fig"}). The diet also had an effect on the fasting glycemia to plasma insulin ratio (*F* = 3.6, *P* = 0.041) that is commonly taken as an indicator of insulin sensitivity. In particular, compared to controls (10%-fat fed mice), the ratio of glucose to insulin was reduced by 94 ± 42% (*P* = 0.034) and 95 ± 42% (*P* = 0.033) in mice from the 45%-fat or 60%-fat groups, respectively. An oral glucose tolerance test after this fasting period revealed an impairment of blood glucose clearance that wasalso proportional to the amount of fat present in the diet (*F* = 14.6, *P* \< 0.001, Figure [1E](#F1){ref-type="fig"}). This is especially clear when looking at the glycemia at 2 h post the glucose administration (*F* = 13.5, *P* \< 0.001, Figure [1F](#F1){ref-type="fig"}), with 60%-fat fed mice displaying increased glycemia compared to both 45%-fat fed mice (+32 ± 14%, *P* = 0.033) and controls (+109 ± 21%, *P* \< 0.001). HFD also affected the circulating concentrations of corticosterone (*F* = 4.2, *P* = 0.025, Figure [1G](#F1){ref-type="fig"}) and leptin (*F* = 19.0, *P* \< 0.001, Figure [1H](#F1){ref-type="fig"}). In *post hoc* tests, corticosterone was only significantly different between mice under diets with 10% and 60% fat (+32 ± 11%, *P* = 0.007), while leptin was similarly increased in both HFD