Monday, 18 April 2011

The State Department last week released its annual human rights report. Once again, the Council for Global Equality applauds the State Department’s effort to “provide an overview of the human rights situation around the world as a means to raise awareness of human rights conditions, in particular as these conditions affect the well-being of women, children, racial and religious minorities, trafficking victims, members of indigenous groups and ethnic communities, persons with disabilities, sexual minorities, refugees, and members of other vulnerable groups.” And once again this year, the report bears witness to a clear and growing crisis in human rights abuse directed against lesbian, gay, bisexual, and transgender (LGBT) people worldwide.

For the second year in a row, every country chapter now includes a section on “societalalso makes clear that LGBT rights are not special rights, but that they are firmly rooted in basic human rights protections that are shared by all, regardless of sexual orientation or gender identity, and that those protections are under severe attack in the world today.

The preparation of the annual report, which covers 194 countries, is a herculean task that requires careful attention to detail. As such, it’s more of a kabuki dance than a liberation march. Every word is carefully calibrated and then reviewed and debated within the State Department to ensure that it sends the proper diplomatic message. As such, the reports tend to be repetitive from one year to the next. If the human rights landscape has not improved on a given issue, as is far


muscle of the United States, through our embassies, our UN missions and our State Department, to respond to the egregious LGBT abuses that we read about in the annual report? How do we navigate the troubled waters of international advocacy, where our adversaries attempt to deflect our human rights arguments by complaining of neo-imperialism, and where even many of our friends in the developing world fear that the U.S. message is tainted by our country’s own human rights shortcomings, both in respect to our LGBT citizens and to others? The answer is certainly not to let this commendable report fade into the background current of geopolitical doublespeak. The answer is to work harder to improve the lives for LGBT Americans, and to use those advances to prod otherhis career! So he sucked at it.....duh!

Now he sees the value in a punter so great that he needed to blow a 3rd rounder on him??? What is this amateur hour? This dude is learning on the job and costing this team W's!

Look at the QB and WR situations last year......he blew that royally also! Even you knew we needed WR in the off-season last year Teal (Gene 2011: "We like the guys we have, they are better than people think")!

You are correct about the third rounders not always being starters, but Sean Spence sure would have been a nice safety net for an aging injury prone Session or a possible "testing the market" next year Daryl Smith....but im no Gene Smith, so what do I know!
The better


1. Introduction {#sec1-antibiotics-09-00509}
===============

Natural products and their derivatives are preeminent sources of lead compounds for pharmaceutical development, accounting for \>50% of all small molecule-based drugs in current clinical use \[[@B1-antibiotics-09-00509],[@B2-antibiotics-09-00509]\]. The influence of natural product chemistry on drug discovery has not materially decreased for more than 30 years, with drug approval statistics over the past decade providing unequivocal evidence that natural product scaffolds remain the ideal starting point for the development of new medicines \[[@B3-antibiotics-09-00509]\]. Despite this, enthusiasm for natural products within the pharmaceutical industry has progressively waned since the early 1990s, usurped by structure-guided approaches and combinatorial chemistry. Regrettably, the decision to transition away from natural products as a starting point for drug discovery has led to a decline in the productivity of the pharmaceutical industry, with aOSMAC screen used ISP2 as a base and the results shown in [Figure 8](#antibiotics-09-00509-f008){ref-type="fig"} indicate that the ability of bacteria to grow on an altered OSMAC agar was not linked to their ability to inhibit pathogen growth. For example, over three times as many isolates grew on ISP2 at pH = 9 compared to pH = 5 (57 versus 16). However, fewer of the pH = 9 isolates inhibited pathogen growth; only 2 isolates versus 10 grown at pH = 5. Intriguingly almost all strains with antimicrobial activity showed activity on only a single medium, implying a specific requirement for that condition rather than a general effect.

We attempted to corroborate the results of the OSMAC screen by re-culturing and re-screening those strains with antimicrobial activity. The growth inhibition


probability of bioactivity.

Despite numerous advances in the field of bioprospecting, traditional screening approaches continue to represent the dominant methodology that results in the discovery of novel compounds \[[@B32-antibiotics-09-00509]\]. Successfully isolating novel producers is an essential part of reducing the risk of rediscovery and maximising the usefulness of samples from underexplored environments. A previous study by Esteves et al. \[[@B33-antibiotics-09-00509]\] indicated that increasing media diversity represents an important strategy for increasing the diversity of cultured bacteria. Even the most effective sponge culturing studies (i.e., the most bacteria cultured in total) can only achieve \~10--14% recovery of species associated with a sponge sample \[[@B34-antibiotics-09-00509]\], and given the extreme nature of the deep-sea environment we expected to achieve significantly less than this. While uncultured bacteria represent a promising avenue for novelThere were five sampling locations from east to west: Carter and Knipovich seamounts in the eastern basin, the Vema fracture zone at the Mid-Atlantic Ridge and the Vayda and Gramberg seamounts in the western basin.

The environmental conditions of the sites were recorded and varied as follows: temperature (2.8--9.9 °C), salinity (34.9--35.1 PSU), and oxygen molality (36.8--236.3 umol/kg). There are four classes of marine sponges---Calcarea, Demospongiae, Hexactinellida, and Homoscleromorpha---and all but the last class were collected. The sponges were photographed and subsampled in a controlled-temperature (4 °C) laboratory on board the ship before flash freezing them for storage at −80 °C.

4.2. Sponge Processing and Isolation of Bacterial Strains {#sec4dot2-antibiotics-09-00509}
---------------------------------------------------------

Sponge samples (1 g) were washed three times in 50 mL sterile artificial sea water (ASW; Crystal Sea Marine Mix, Marine


of the 22 OSMAC hits from the first screen on ISP2 media; **Table S5.** ISP2 media for first OSMAC screen; **Table S6.** M9 media for second OSMAC screen, and supplementary references.

######

Click here for additional data file.

C.R.B., H.L.S., S.E.W., K.T., J.O.G. and M.R.C. designed, performed and analysed the experiments. K.R.H. collected the sponge samples. C.R.B., H.L.S. and S.E.W. wrote the original draft of the manuscript. K.R.H., A.E.E.-L., J.S., C.L.W., P.C. and P.R.R. reviewed and edited the manuscript. K.R.H., A.E.E.-L., J.S., C.L.W., P.C. and P.R.R. provided supervision. P.C. and P.R.R. conceived the project and acquired funding. All authors have read and agreed to the published version of the manuscript.

This work was funded by BBSRC grants BB/T001968/1, BB/L01386X/1 and BB/M025624/1, and through the award of PhD studentships to SEW fromLG to offer new triple-SIM featurephone

Looking around the mobile space, you don’t see a lot of news on upcoming feature phones – especially ones that are only announced for Russia. Yet LG’s A290 is worth noting, as it will be the first phone from a major manufacturer to offer three different SIM slots. So for those of you who need a world phone with three different numbers (or networks) this is the phone for you.

Well, as long as “you” happens to live in Russia you'll be able to pick one up in February. The phone seems poised to put some pressure on Nokia’s Russian marketshare; Nokia apparently sells a lot of dual-SIM featurephones in Russia, and checking out the gallery below, the LG N290 has more than a


your Android.

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RESULTS AND DISCUSSION {#sec1-3}
======================

Selection of the detection wavelength {#sec2-6}
-------------------------------------

The absorption spectra of the three sample extraction and rutin solutions were obtained. The absorption peak of rutin was at 510 nm and **S. lineare** Thunb. at 500nm, while both **S. lineare** Thunb. and *S. erythrostictum* Migo. solutions had strong absorptions at a little less than 500 nm. Comprehensively, 500 nm was chosen as the detection wavelength.

Optimization of the extraction solvent {#sec2-7}
--------------------------------------

Since flavonoids contain some hydroxyl groups, they often dissolve easily in alcohol or alcohol--water mixtures. The *S. sarmentosum* Bunge. sample (Jianshi, June 28, 2006) was employed here, trying to find out the optimum solvent for sample extraction. The relationship between alcohol concentration and the yield of the total flavonoids is shown in [Figure 1](#F0001){ref-type="fig"}. In the figure, we could


Evaluation of the efficacy and effectiveness of a structured disorder tailored psychotherapy in ADHD in adults: study protocol of a randomized controlled multicentre trial.
ADHD is a serious risk factor for co-occurring psychiatric disorders and negative psychosocial consequences in adulthood. Previous trials on psychotherapeutic concepts for adult ADHD are based on behavioural (cognitive behavioural and dialectical behavioural) psychotherapeutic approaches and showed significant effects. The aim of our study group (COMPAS) is to carry out a first randomized and controlled multicentre study to evaluate the effects of a disorder tailored psychotherapy in adult ADHD compared to clinical management in combination with psychopharmacological treatment or placebo. A total of 448 adults with ADHD according to DSM-IV will be treated at seven university sites in Germany. In a four-arm design, patients areBhopal: The Congress government in Madhya Pradesh has stirred a major controversy by announcing that it will review and withdraw “false cases” against Muslims and Christians , filed by the previous BJP government out of alleged political vendetta. BJP has dubbed it “politics of appeasement” and a bid to legalise and promote conversions, which is against the law.The Kamal Nath government has already announced amnesty in “politically-motivated cases” filed by the previous BJP rule against political workers and activists, and cases filed against farmers during kisan agitations.“We have decided to withdraw all ‘false cases’, which were politically motivated, including those registered against Muslims and Christians, by the previous BJP government,” law minister P C Sharma said on Tuesday. Asked about BJP’s allegation that the Congress government wants to


"Well, in that hit you miss." "She'll not be hit with Cupid's arrow;" "...nor bide the encounter of assailing eyes nor ope her lap to saint-seducing gold." "Then she hath sworn that she will still live chaste?" "She hath, and in that sparing makes huge waste." " Be ruled by me." "Forget to think of her." " Teach me how I should forget to think." "By giving liberty unto thine eyes." "Examine other beauties." "Why, Romeo, art thou mad?" "Not mad, but bound more than a madman is." "Shut up in prison, kept without my food, whipp'd and tormented." "Good day, good fellow." "Now, I'll tell you without asking." "The great rich Capulet holds an old accustom'd feast." "A fair assembly." "Signor Placentio and his wife and daughtersnurse!" "What news?" " Nurse!" " I am aweary!" "Give me leave awhile!" "Fie, how my bones ache!" "What ajaunce have I!" "Would thou hadst my bones and I thy news." "Come, I pray thee, speak!" "Jesu, what haste!" "Can you not stay awhile?" "Can you not see that I am out of breath?" "How art thou out of breath when thou hast breath to say to me that thou art out of breath?" "Is the news good or bad?" "Answer to that." "Well, you have made a simple choice." "You know not how to choose a man." "Romeo?" "No, not he." "Though his face be better than any man's yet his leg excels all men's and for a hand and a foot and a body..." "But all


budge for no man's pleasure, I." "Peace be with you, sir." "Here comes my man." "Mercutio!" "Romeo!" "The love I bear thee can afford no better term than this." "Thou art a villain!" "Tybalt the reason that I have to love thee doth much excuse the appertaining rage to such a greeting." "Villain am I none." "Therefore, farewell." "I see thou knowest me not." "Boy, this shall not excuse the injuries that thou hast done me!" "Turn and draw!" "Turn and draw!" "Turn and draw." " Turn and draw!" " I do protest I never injured thee but love thee better than thou canst devise till thou shalt know the reason of my love." "And so, good Capulet whose name I tender as dearly as mine own besatisfied." "Be satisfied." "O calm, dishonourable, vile submission!" "Thou art my soul's hate!" "Tybalt!" "You rat-catcher!" "Will you walk?" "What wouldst thou have with me?" "Good King of Cats, nothing but one of your nine lives!" "I am for you!" "Forbear this outrage, good Mercutio!" " Art thou hurt?" " Ay, ay, a scratch, a scratch." "A scratch!" "Ay, a scratch..." "A scratch!" "Courage, man." "The hurt cannot be much." "'Twill serve." "Ask for me tomorrow and you shall find me a grave man." "A plague... o' both your houses!" "They have made worms' meat of me." "A plague on both your houses!" "Your houses!" "Your houses!" "Your houses!" "Your houses!" "No!" "Why the devil came you between us?" "I was hurt under your arm." "I thought all


Q:

Employer does not withhold state taxes

I live in GA where there is a state income tax. I work in TN where there is no income state tax. My company does not operate a business in GA and are telling me they cannot withhold GA taxes for this reason. Is this accurate?

A:

As indicated by the comments to the question (credit: RonJohn), if the TN company has no GA presence then they may not need to setup GA payroll/income tax withholdings. It may be more of a question of not wanting to deal with the paperwork/red ink/bureaucracy of paying state taxes for a single employee, who could decide to move elsewhere in the future.
Instead, you are most likely responsible for making estimated tax payments to the state of GA, for    }
        "Asia:Qyzylorda"{
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            ec{"Rangoun"}
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            ec{"Riyad"}
        }
        "Asia:Saigon"{
            ec{"Hô-Chi-Minh-Ville"}
        }
        "Asia:Sakhalin"{


l’Acre"}
            ls{"heure normale de l’Acre"}
        }
        "meta:Afghanistan"{
            ls{"heure normale d’Afghanistan"}
        }
        "meta:Africa_Central"{
            ls{"heure normale d’Afrique centrale"}
        }
        "meta:Africa_Eastern"{
            ls{"heure normale d’Afrique de l’Est"}
        }
        "meta:Africa_Southern"{
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S1 gives the indexing time and required storage.

PERFORMANCE EVALUATION
======================

This section describes the efficiency and flexibility of RNAMST. Several well-known RNA motifs in Rfam ([@b18]) are used to search for structural homologs against the sequences with different sizes, and the search time are compared with those experiments done using RNAMotif ([@b14]).

To evaluate the performance of searching for structural homologs among large numbers of sequences, RNAMotif ([@b14]) is compared with RNAMST developed here in searching for two kind of RNA motifs, iron response element (IRE) ([@b19]) and purine riboswitch ([@b5]), with different sized databases.

Supplementary Figure S1 shows the RNA structural motif of IRE, which is a short and conserved stem--loop found in UTRs of various mRNA. The IRE regulates mRNA translation by interacting with iron regulatory proteins ([@b19]). The RNAstructural descriptor of IRE is given in Supplementary Figure S1. [Figure 2](#fig2){ref-type="fig"} gives the comparison of the search time of RNABOB, RNAMotif and RNAMST with different sized databases. For example, RNABOB and RNAMotif spent 231 and 25 s in detecting homologs of IRE motifs in UniGene human sequence database, respectively, while our RNAMST only needed 13.3 s to accomplish the same search. Since IRE is a very small motif and is highly conserved, the constraint of the IRE structural descriptor is quite strict, making it easy to be detected. Despite this, RNAMST is still ∼9 and 1.9 times faster than RNABOB and RNAMotif, respectively, and the difference increases as the structure becomes more complex and the constraints loosen.

Supplementary Figure S2 gives the RNA structural descriptor of purine riboswitch,


to select the sequences of interest. Accordingly, users can conveniently and rapidly search these databases for homologs of an input RNA structural motif.

Thirdly, the predictive constraints can be specified by users. Besides the input of the structural descriptor, the other formats can set the search similarity constraint to add the mispairs and bulges for the query structural motif. RNAMST supports two kinds of base pairing to fold helices: Watson--Crick pairing (AT and GC pairing), and both Watson--Crick pairing and G--U pairing.

Finally, the RNAMST generates the output for the discovered RNA structural homologs, as well as provides additional information for further analysis, including description of the search sequence containing the homologs, alignment and RNA secondary structure of the homolog.

DISCUSSIONS AND CONCLUSION
==========================

RNAMST markedly improves the search time compared with other                   'language'=>'English',
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Language    English English

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analysis showed that nanoparticles were spherical in shapes. In nanoparticles, docetaxel was present in its amorphous form as confirmed by DSC and PXRD analysis and was stable during the thermal studies. The formulations showed the sustained release of DTX over the period of 120 h. During cellular toxicity assay in gastrin releasing peptide receptor positive breast cancer cells (MDA-MB-231), BDNP were found to be 12 times more toxic than pure DTX and Taxotere. The IC50 value for DTX, Taxotere, DNP and BDNP was >375, >375, 142.23 and 35.53 ng/ml, respectively. The above studies showed that Bombesin conjugated nanocarrier system could be a promising carrier for active targeting of anticancer drugs in GRP receptor over expressing cancer cells.


the evidence, both parties moved for a directed verdict. The trial court granted RES's motion for directed verdict and denied appellant's motion and appellant filed this appeal.
1. Appellant alleges the trial court erred in granting RES's motion for directed verdict and in denying his own motion for directed verdict. Specifically, appellant argues that RES is liable to him because: (1) he has a claim for breach of contract against Air Center under the original lease to operate the airport and RES is a successor lessee under that lease and (2) RES entered into an asset purchase agreement with Air Center in which it assumed Air Center's liabilities and obligations under the operating agreements and tenant agreements, which included Air Center's responsibility to appellant for the damage suffered toAlcohol use after forced abstinence in basic training among United States Navy and Air Force trainees.
The present study examined drinking rates of U.S. Navy and Air Force trainees during the month before attending basic training and after the ban on drinking alcohol was lifted during advanced training. Surveys were obtained at five training bases (one U.S. Navy, four U.S. Air Force) from 6,298 persons for a response rate of 65%. Analyses were based on 4,962 young adults ages 18-25 (82% male) who gave valid responses about pre-basic drinking. Findings showed a rate of 43.1% heavy episodic drinking during the month before basic training, 15.8% by infrequent heavy episodic drinkers (five or more drinks per occasion at least once, four or more for women), and 27.3% by frequent heavy


held that Lunini had indeed alleged violation of a clearly established constitutional right: "[A]ction depriving a citizen of police protection at the purely personal request of a government official [as Lunini alleges4] was unrelated to any legitimate state objective, and denied the citizen the right to equal protection of the law." 305 F.Supp.2d at 911 (citing Hilton v. City of Wheeling, 209 F.3d 1005 (7th Cir.2000) and Olech v. Village of Willowbrook, 160 F.3d 386 (7th Cir.1998)). We review rulings on motions for summary judgment de novo. Reed v. McBride, 178 F.3d 849, 852 (7th Cir.1999). Summary judgment is warranted when the evidence, when viewed in a light most favorable to the non-moving party, presents "no genuine issue as to any material fact" such that "the moving partyto note, must be undertaken in light of the specific context of the case, not as a broad general proposition .... the right the official is alleged to have violated must have been "clearly established" in a more particularized, and hence more relevant, sense: The contours of the right must be sufficiently clear that a reasonable official would understand that what he is doing violates that right. The relevant, dispositive inquiry in determining whether a right is clearly established is whether it would be clear to a reasonable officer that his conduct was unlawful in the situation he confronted.

28
Id. (internal citations and quotations omitted). The plaintiff bears the burden of establishing that a given right is "clearly established," Rice v. Burks, 999 F.2d 1172, 1174 (7th Cir.1993), and


all protection from [plaintiff] out of sheer malice, or because they had been bribed by his neighbors, he would state a claim under Olech," but "the absence of evidence of an improper motive" is decisive. Id. at 1008. We concluded by summarizing that "to make out a prima facie case [for a class of one equal protection violation] the plaintiff must present evidence that the defendant deliberately sought to deprive him of the equal protection of the laws for reasons of a personal nature unrelated to the duties of the defendant's position." Id.

34
Clearly, Hilton comes closest to the instant case. It involves allegations of unequal police response to complaints by local residents; additionally, its dictum regarding actions taken "for reasons of a personal nature unrelated to the dutiesone cases).

35
Certainly Lunini is unhappy with defendant police officers' response to the incident at the High Street residence. However, on this record it appears highly doubtful that any alleged police misjudgments (if misjudgments there were) took on constitutional proportions. While we take pains to affirm the baseline principle that police support and protection must be afforded to all citizens on a non-discriminatory basis, we decline to take the unprecedented step of implying a general constitutional police duty to arrest certain individuals during a response to an isolated domestic incident. Such a ruling would threaten to turn every police house call into a potential federal constitutional lawsuit. Cf. Olech, 528 U.S. at 565-66, 120 S.Ct. 1073 (Breyer, J., concurring) (warning against a rule that "would transform many ordinary violations


with European partners through recently established electricity lines with Poland (LitPol Link), Sweden (NordBalt) and Finland (Estlink 1 and Estlink 2). These projects were made possible and built with EU support. For historical reasons, however, the Baltic States' electricity grid is still operated in a synchronous mode with the Russian and Belarusian systems.

The desynchronisation of the Baltic States' electricity grid from these systems and the synchronisation with the continental European network (CEN) is an essential political priority for the achievement of the Energy Union. The relevant grid reinforcements have been included in the third EU list of Projects of Common Interest (PCIs) adopted by the Commission on 23 November 2017. On 19 March 2019, the Connecting Europe Facility grant agreement was signed for the €323 million financing forthe first phase of the synchronisation process, covering 75% of the investment needs for this phase. In May 2019, the formal extension of the continental European grid to the Baltic States' was approved within the ENTSO-E in a process initiated by Poland. Source: http://europa.eu/rapid/press-release_IP-19-3337_en.htm


Russia investigation seeks 1st charges, indictment announcement may come as soon as Monday, sources say Robert Mueller's team sought charges against at least one unidentified person

 -- The special counsel team investigating Russia's alleged meddling in the 2016 election and possible links to the campaign of President Donald Trump has sought charges against at least one unidentified target, ABC News has learned.

Sources tell ABC News an indictment announcement and arrest could possibly come as early as Monday.

A spokesman for the special counsel's office declined to comment.

CNN first reported a federal grand jury approved charges brought by Special Counsel Robert Mueller’s team.

Attorneys from Mueller's office were at the federal courthouse in Washington, D.C., on Friday, including one of his senior prosecutors who specializes in fraud cases. ABC News confirmedfeel the need to do that?" "Let's just stick with the professional version." "Grrrr!" "Come on, let's get busy!" "So you're the genius behind this incredible brew." "The whole city is buzzing about you." "I hope Pao pays you well." "Good tea is its own reward." "But it doesn't have to be the only reward." "How would you like to have your own tea shop?" "My own tea shop?" "This is a dream come true." "What's going on here?" "Are you trying to poach my tea maker?" "Sorry Pao, that's business for you, am I right?" "Mushie, if you stay, I will make you Assistant Manager." "Wait, Senior Assistant manager." "I'll provide you with a new apartment in the upper ring." "The Tea shop is yours to do


you disappeared at the Earth King's party." "Oh, I simply took a short vacation to Lake Laogai, out in the country." "It was quite relaxing." "But then they replaced you with some other woman who also said her name was Joo Dee." "I'm Joo Dee." "Why are you here?" "Dropping flyers and putting up posters isn't permitted within the city." "Not without proper clearance." "We can't wait around to get permission for everything." "You are absolutely forbidden by the rules of the city to continue putting up posters." "WE DON'T CARE ABOUT THE RULES, AND WE'RE NOT ASKING PERMISSON!" "We're finding Appa on our own and you should just stay out of our way!" "That might come back to bite us in the blubber." "I don't care." "FromUrban Sketchers."
• Luis' art on flickr.

Separation problems

[By Fred Lynch] As I drew with my back to the wall of the abbey of San Martino (built in 1400), cars squeezed by one by one, then headed left or right before me. Pedestrians trickeled by, too. This is the narrowest opening of the walled city of Viterbo, called Porta San Pietro. Looking over at the big wooden door to the entrance, I wondered when was the last time they closed it.

It was the large unusual shadow formation that attracted me to draw here. But as time went on, I became more and more interested in the wall on my right. It held a strange mix of elaborate relief sculpture and clunky electricity boxes. The wall seemed a good illustration of


Porta San Pietro, it would itself be the next problem. That's because the city's water has been found to have unhealthy levels of arsenic, leaving residents to live off bottled water for well over a year. Double trouble.one further output beam path, in which another optical component utilized for the operation of the apparatus is arranged. This has the advantage that a previously unutilized output beam path is utilized for the purpose of generating interference. This means that an additional component for coupling out or generating the light utilized by the interference generating means is not necessary. In this case, the optical element may be a half-mirror or a beam splitter which serves for example for directing the beam reflected from the recording medium onto a detector element. An optical grating which generates possibly unutilized first- or higher-order output beams, if appropriate in the reflection direction, is also a possible configuration of the optical element. The optical recording medium itself, whose grating structure formed by


Q:

Turn off light after 30 second of inactivity

My app is set LCD always on but it loses too much power, I want to dim or turn off LCD light(no sleep or lock) after 50 seconds of inactivity.
I tried some solutions but no one cant cures my problem.
I just want it on one activity, not others.
Please help me with any class or method that I can use for this
Edited:
My main problem:
I want to use hard key of an android device when it locked.
So now tell me,How can i use a hard key as a click in my app when screen locked???
Edit:
i have a device with 5 hard key and i want use them when device locked down.

A:

Keeping the screen on forever is as simple as creating a wakeLock. Turningoff the screen after sometimes (probably 30 seconds or so) will be enabled by default in almost all the Android devices.
I think what you are looking for here is an app that behaves like a media player app/ music playing app. You can do so by running a service in the foreground. You will need to create a persistent notification for this. This way, your app/ activity will not get killed even if the device screen is off.
Find the documentation here: https://developer.android.com/guide/components/services#Foreground
EDIT #1
As discussed in the comments, this link was helpful to the OP for getting the answer to his query: https://stackoverflow.com/a/29818026/3811983


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    boot_vars = {'instance_type': 't1.micro'}
    with boot_manifest(manifest_data, boot_vars) as instance:
        print(instance.get_console_output().output)

def test_gpt_unstable():
    std_partials = ['base', 'unstable64', 'gpt', 'single_partition', 'root_password']
    custom_partials = [partials['ebs_pvm']]
    manifest_data = merge_manifest_data(std_partials, custom_partials)
    boot_vars = {'instance_type': 't1.micro'}
    with boot_manifest(manifest_data, boot_vars) as instance:
        print(instance.get_console_output().output)
Phase V, 2 pigs from each pen were again selected and slaughtered. Generally speaking, the source of trace mineral supplementation, again, and the duration of trace mineral deletion did not change the absolute and relative weights of tissues or the percentage of tissue dry matter content ([Table 5](#t5-ajas-31-2-252){ref-type="table"}).

Tissue mineral status of 80 kg pigs
-----------------------------------

Manganese concentrations from pigs fed OTM were greater (p\< 0.05) than those fed ITM for heart, kidney, liver, and LD muscle ([Table 6](#t6-ajas-31-2-252){ref-type="table"}). Organic Cu resulted in more Cu (p\<0.05) deposited in LD muscle than inorganic Cu and tended (p = 0.06) to result in more Cu in kidney than inorganic Cu. More Fe was deposited (p\<0.05) in LD muscle with organic Fe than inorganic Fe; alternately, more Fe (p\<0.05) was deposited in liver with


60 mg; Mn (oxide), 2.0 mg; Zn (oxide), 60 mg; I (calcium iodate), 1.0 mg, and Se (sodium selenite), 0.3 mg. Supplied per kg of diet during Phase IV (50 to 80 kg): Cu (sulfate), 3.5 mg; Fe (sulfate), 50 mg; Mn (oxide), 2.0 mg; Zn (oxide), 50 mg; I (calcium iodate), 1.0 mg, and Se (sodium selenite), 0.3 mg. Supplied per kg of diet during Phase V (80 to 120 kg): Cu (sulfate), 3.0 mg; Fe (sulfate), 40 mg; Mn (oxide), 2.0 mg; Zn (oxide), 50 mg; I (calcium iodate), 1.0 mg, and Se (sodium selenite), 0.3 mg.

Organic trace minerals were supplied in the form of Bioplex (Alltech Inc., Nicholasville, KY, USA) and provided at 100% of the NRC \[[@b8-ajas-31-2-252]\] requirement estimates for Cu, Fe, Mn, andwas an Indian name, and how lucky he was to have gotten a last name two syllables shorter and way less weird than my own. Mom gave me the Frances Hodgson Burnett books, The Secret GardenandA Little Princess. “The little girls are from India,” she said proudly of the books’ protagonists, as though I could identify with them all the more. But as I scrutinized Tasha Tudor’s full-color illustrations I was confused. Mary Lennox was definitely blonde, there was no doubt about that. And Sara Crewe, well, she did have dark hair, but I really couldn’t see any evidence of brown in her complexion like I had. White girls came from India? How was that possible? (And, more shamefully, how was that fair?) I think my questions were


a school assembly, something about a teenage girl and her nagging mom. Makeda’s voice was small and her words measured and monotone in their non-native tongue. When she read the lines of the mom character, “’…and take down that poster of Ice-T or Lemonade or whatever his name is,’” the audience roared with laughter. Laughing with her. Here was our own Andy Kaufman, and she was good.

I carefully traced the shape of her head, the high, thin brows, and those drowsy-lidded eyes onto the canvas, holding my breath and biting my lip as I usually did in those first few minutes of a drawing when I was determined to prove my rendering skills. As I was shading in the cherub mouth that said the things that made usthis guy." " Oh, Lord!" "Yes!" "Richmond, Virginia." "Smell my ass!" "After he smells mine." "That's a shame about your horse coming in last and all." "But I sure do love that winning horse of mine, though." "I owe that boy a big kiss when I see him." "Why don't you give him some of your cigarettes instead?" "Lucky fuck!" "Hey, Tyrell." "You pull infirmary duty this week?" "How's my horse doing anyway?" "Dead." "Hadley busted his head up pretty good." "Doc had gone home for the night." "Poor bastard lay there till this morning." "By then, there wasn't nothing we could do." "What was his name?" "What'd you say?" "I was just wondering if anyone knew his name." "What the fuck do you care, new fish?" "Doesn't


limestone." "So?" "So I'm a rock hound." "At least I was in my old life." "I'd like to be again." "Or maybe you'd like to sink your toy into somebody's skull." "No, I have no enemies here." "No?" "Wait a while." "Word gets around." "The Sisters have taken quite a liking to you." "Especially Bogs." "Don't suppose it would help if I told them I'm not homosexual." "Neither are they." "You have to be human first." "They don't qualify." "Bull queers take by force." "That's all they want or understand." "If I were you, I'd grow eyes in the back of my head." " Thanks for the advice." " Well, that's free." "You understand my concern." "If there's trouble, I won't use the rock hammer." "Then I'd guessme stay." "This is crazy." "You don't want to do this." "Put it, put it down." "Take it easy." "You'll be all right." "Him?" "What about me?" "Crazy old fool damn near cut my throat!" "You've had worse from shaving." "What did you do to set him off?" "Nothing." "I come in here to say farewell." "Ain't you heard?" "His parole's come through." "I just don't understand what happened in there." "Old man's crazy as a rat in a tin shithouse." "That's enough out of you." " Heard he had you shitting your pants." " Fuck you." "Knock it off." "Brooks ain't no bug." "He's just institutionalized." ""Institutionalized," my ass." "The man's been in here 50 years, Heywood, 50 years!" "This is all he knows." "In here, he's


to the park and feed the birds." "I keep thinking Jake might just show up and say hello." "But he never does." "I hope, wherever he is, he's doing okay and making new friends." "I have trouble sleeping at night." "I have bad dreams like I'm falling." "I wake up scared." "Sometimes it takes me a while to remember where I am." "Maybe I should get a gun and rob the Food-Way so they'd send me home." "I could shoot the manager while I was at it." "Sort of like a bonus." "I guess I'm too old for that sort of nonsense anymore." "I don't like it here." "I'm tired of being afraid all the time." "I've decided not to stay." "I doubt they'll kick up any fusstwo-year stretch for B and E." "That's breaking and entering to you." "Cops caught him sneaking TV sets out the back door of a JC Penney." "Young punk." "Mr. Rock 'n' Roll cocky as hell." "Come on, old boys." "Moving like molasses!" "Making me look bad." "We liked him immediately." "I'm backing out the door and I got the TV like this." "A big old thing." "I couldn't see shit." "Then I hear this voice." ""Freeze, kid, hands in the air."" "I was standing there, holding onto that TV." "Finally the voice says:" ""You hear what I said, boy?" I say, "Yes, sir." "I did." "But if I drop this, you get me on destruction of property too."" "You done some stretch in Cashman, right?" "Yeah, that was


sure do." "Right there." ""Dufresne."" "He was in his cell at lights out." "Reasonable he'd be here in the morning." "I want him found." "Not tomorrow, not after breakfast." "Now!" "Yes, sir." "Let's go." "Move your butts." "Stand." "Well?" "Well, what?" "I see you two all the time." "You're thick as thieves, you are." "He must have said something." "No, sir, Warden." "Not a word." "Lord, it's a miracle!" "Man vanished like a fart in the wind." "Nothing left but some damn rocks on a windowsill." "And that cupcake on the wall." "Let's ask her." "Maybe she knows." "What say there, fuzzy-britches?" "Feel like talking?" "Guess not." "Why should she be any different?" "This is a conspiracy." "That's what this is." "One big, damn conspiracy!" "And everyone's inon it!" "Including her!" "In 1966 Andy Dufresne escaped from Shawshank Prison." "All they found was a muddy set of prison clothes a bar of soap and an old rock hammer damn near worn down to the nub." "I had thought it'd take a man 600 years to tunnel through the wall with it." "Old Andy did it in less than 20." "Oh, Andy loved geology." "I imagine it appealed to his meticulous nature." "An ice age here million years of mountain building there." "Geology is the study of pressure and time." "That's all it takes, really." "Pressure and time." "That and a big goddamn poster." "Like I said in prison, a man will do anything to keep his mind occupied." "Seems Andy's favorite hobby was toting his


wall out into the exercise yard a handful at a time." "I guess after Tommy was killed Andy decided he'd been here long enough." "Lickety-split." "I want to get home." "I'm just about finished, sir." "Three deposits tonight." "Andy did like he was told." "Buffed those shoes to a high mirror-shine." "The guards simply didn't notice." "Neither did I." "I mean, seriously how often do you really look at a man's shoes?" "Andy crawled to freedom through 500 yards of shit-smelling foulness I can't even imagine." "Or maybe I just don't want to." "Five hundred yards." "That's the length of five football fields." "Just shy of half a mile." "The next morning, right about the time Raquel was spilling her secret a man nobody ever laid eyes onshit." "Here you go, miss." "Restroom break?" "You don't need to ask me every time you need to go take a piss." "Just go." "Forty years I've been asking permission to piss." "I can't squeeze a drop without say-so." "There's a harsh truth to face." "No way I'm going to make it on the outside." "All I do anymore is think of ways to break my parole so maybe they'd send me back." "Terrible thing, to live in fear." "Brooks Hatlen knew it." "Knew it all too well." "All I want is to be back where things make sense." "Where I won't have to be afraid all the time." "Only one thing stops me." "A promise I made to Andy." "There it is." "Much obliged, sir." "Dear Red:"


   2016,       12:47         PM),
http://www.npr.org/2016/01/28/464594826/in‐wake‐of‐videos‐planned‐
parenthood‐investigations‐find‐no‐fetal‐tissue‐sales  (summarizing  re‐
sults of investigations).
26                              Nos. 18‐1146, 18‐1247 & 18‐1308

      thing. But I think actually allowing the fetal tis‐
      sue to be used for research purposes seems to be
      outlawed in this bill.
      S. Holdman: Well, I wouldn’t say that it [research
      with fetal tissue] is outlawed. I think the word au‐
      topsy  encompasses  that  research  portion  of
      what is done with that piece of tissue that is di‐
      agnosed  after  the  fact  through  an  autopsy.  So
      maybe it is just a matter of semantics, here, per‐
      haps  Senator  Stoop.  But  autopsy  is  the  word
               31

enact more carefully drawn regulations,” id., but that was a
legislative job—not a prosecutorial or judicial one.5
    The majority also reads too much into Bauer v. Shepard, 620
F.3d 704, 706–07 (7th Cir. 2010), which considered a challenge
by two Indiana judges and an advocacy group to provisions
of Indiana’s Code of Judicial Conduct. In Bauer, the plaintiff‐
judges feared that responding to the group’s questionnaires
might violate the state’s judicial ethics code. In that case, the
Commission on Judicial Qualifications might issue public ad‐
monitions (if the subject of the admonition agreed), or a court
of appeals could remove the judge from a particular case, or,
as a matter of last resort, “the state’s Supreme Court c[ould]
remove  [the]  judge  from  office  or  impose  substantial  disci‐
pline.” Id. at 707–08. We acknowledged that “[t]o the extent
there  is  uncertainty”  regarding  some  provisions,  “Indiana
provides means of clarification,” and the Commission on Ju‐
dicial Qualifications “already has issued several clarifying ad‐
visory opinions.” Id. at 712. Judges who worried about further
applications  of  the  Code  should  “wait  and  see,”  we  said,
given that beyond the “advisory opinions that reduce uncer‐
tainty,” when the “Commission brings a proceeding the state
judiciary will issue an opinion that makes the rule more con‐
crete.” Id. at 716.
    The majority quotes at length from Bauer to explain that it
is “more respectful of our judicial colleagues in Indiana, to as‐

     5 The  majority  writes  that  Akron  was  “overruled”  by  Planned
Parenthood  of  Southeastern  Pennsylvania  v.  Casey,  505  U.S.  833  (1992),  but
Casey did not overrule any portion of Akron dealing with the vague crim‐
inal statute on fetal remains.
32                                                  Nos. 18‐1146, 18‐1247 & 18‐1308

sume  that they  will act sensibly and  resolve  the open ques‐
tions in a way that honors candidates’ rights under the first
amendment.  When  a  statute  is  accompanied


Committee
Hearing at 1:47:22–1:47:32 (Feb. 24, 2016). But it is our job to
insist that the effort remain within constitutional parameters:
that  a  new  criminal  law  give  fair  notice  of  what  is  criminal
and what is not, and that the legislature make the key choices
rather  than  delegate  them  to  prosecutors  and  courts.  That
simply did not happen with § 1.5. I would affirm the district
court’s injunction against its enforcement as written.
    Takings Claim: Finally, we should not decide the merits of
Indiana  University’s  claim  for  taking  of  private  property
without compensation. That claim simply is not ripe yet. The
majority mistakenly asserts that the statute “does render val‐
ueless any fetal tissue, derived from abortions, owned by In‐
diana University.” Ante at 11. That is not consistent with the
position taken by the law’s defenders. They insist that Indiana
University remains free to conduct research with materials on
hand, and even to transfer it at the request of the NIH. Supra
at 21–22.
    More fundamental, the legal status of Indiana University
vis‐à‐vis the state government is more nuanced than the ma‐
jority acknowledges. For example, it is well‐established that
the university is an arm of the state for purposes of the Elev‐
enth Amendment and is a state actor for purposes of the Four‐
teenth  Amendment  and  other  constitutional  provisions.  See
Medlock v. Trustees of Indiana University, 738 F.3d 867, 871 (7th
Cir. 2013); Power v. Summers, 226 F.3d 815, 818 (7th Cir. 2000).
But  Indiana  law  does  not  always  treat  the  university  as  the
state,  particularly  when  it  comes  to  property.  See  Sendak  v.
34                                Nos. 18‐1146, 18‐1247 & 18‐1308

Trustees  of  Indiana  University,  260  N.E.2d  601,  603–05  (Ind.
1970)  (university  not  subject  to  constitutional  bar  to  owner‐
ship of private stock); State Board of Accounts v. Indiana Univer‐
sity Foundation, 647 N.E.2d 342, 352 (Ind. App. 1995) (univer‐
sity is “state” for purposes of State Board of Accounts statute
but not in accepting and administering private gifts). The ma‐
jority seems to imply that state legislators could simply con‐
fiscate  private  gifts  and  grants  to  the  university  (as  distinct
from a private foundation associated with it) and use them for
more  general  state‐government  purposes.  That  would  be  a
troubling prospect for many donors and grantors. We would
do better to say that the university’s takings claim is simply
not yet ripe because the actual scope of the challenged statute
remains in so much doubt.
connection is disguised in the shirts’ marketing—the brand is simply “Wyatt Ingraham.” But Koch, who is featured in the video driving a Humvee and partying on a yacht, became a conveniently cartoonish symbol of the kind of person who stands to benefit from the Republicans’ massive tax giveaway: you couldn’t really find a more amusing counterpoint to the idea that the rich are useful to society.

Koch presents such an exaggerated image of the “leisure class” that he seems to have stepped straight out of a piece of Soviet anti-capitalist propaganda. He is the child of a billionaire who appears to spend most of his time shopping, lunching, and playing tennis at Mar-a-Lago. He has contributed nothing of any obvious worth to the world—save a series of unfortunate designer


can help." " Daniels...shirt!" " Yeah Chas, sorry." "Tell me, your father wouldn't be Francis Quilter QC?" "You know him?" "One of the few silks to be highly respected by both the criminal fraternity and the police force." "Everyone loves my father." "Will you follow in his footsteps?" "I have a conditional place in Trinity to read law." "Lot of hard graft first, though." "Glad you're not taking anything for granted." "I'm bright, but I'm not clever, if you know what I mean." "If I want get grades I need, I can work hard for them." "Must be lots of boys with successful fathers here." "At ã6,000 a term, one could take that as a given, Sargent." " But not Matthew's father, sir." " Sorry?" "His dad was"Why did you assume it was Clive who told you to come here?" "Because he's the only one who knew about me and Hugh, a position of privilege which he ruthlessly exploits to his advantage." "You expect me to believe, John, that someone like you is in the pocket of someone like him?" "Do you imagine for one minute I allow Pritchard the run of Erebus out of choice?" "You and Matthew were pretty close, weren't you?" "Did you used to help each other with your homework, that sort of thing?" "If I'd had someone to help me with my homework, maybe I wouldn't have ended up in the police force." "Did, um, you and Matthew ever share things?" "Not like sweets and books and stuff, but... but


Bone is a living tissue and plays a structural role in the body. Bone consists of repeating Harvesian systems (concentric layers of lamellae deposited around a central canal containing blood vessels and nerves). The central canal is also known as the medullary cavity and is filled with bone marrow. Within the shaft of a long bone, many of these Harvesian systems are bundled together in parallel, forming a kind of bone called compact bone, which is optimized to handle compressive and bending forces. In some bones, such as the metacarpals, the bones themselves are hollow and contain little, if any, marrow. Near the ends of the bones, where the stresses become more complex, the Harvesian systems splay out and branch to form a meshwork of cancellous or spongygive up work to do it yourself. Money enables choice. So, should a priority for Government be enabling carers of all incomes to have choices?

Technically, social services should provide care to meet all needs of the disabled or seriously ill person, and should only reduce what they provide if the carer is willing and able to provide certain levels of care. However, the reality is that it is assumed that carers will provide care and social services will only top up on the care that the carer cannot provide.

One woman I know has a husband who has a serious condition. Social services told her that it would cost them over £100,000 p/a to provide care to meet his needs, and that they couldn’t afford this. And despite her


[An adult case of mediastinal tuberculous lymphadenitis].
A 40-year-old woman was admitted to the hospital with general fatigue and cough. Chest CT films revealed mediastinal lymphadenopathy with multiple low density areas, but no pulmonary lesions. There were no abnormal findings on neck, abdominal or pelvic CT. A PPD skin test was strongly positive, but M. tuberculosis bacilli were not found in the sputum. Mediastinal tuberculous lymphadenitis was diagnosed histologically and bacteriologically from specimens obtained by mediastinoscopy. Fiberoptic bronchoscopy did not reveal tracheobronchial tuberculosis. Follow-up chest CT three months after the start of antituberculosis chemotherapy with isoniazid, rifampicin and ethambutol hydrochloride showed that the mediastinal lymph nodes were decreased in size. Mediastinal tuberculous lymphadenitis in adults is rare, but the number of reports has increased. Mediastinal tuberculous lymphadenitis in adultsa judgment partially forfeiting

 4 the bail bond it posted on behalf of Defendant Ramon Lorenzo. Howell argues that

 5 forfeiture of the bond was improper because the district court did not send it

 6 written notice within four days of the district court’s declaration of forfeiture of the

 7 bond, as required by NMSA 1978, Section 31-3-2(B)(2)(b) (1993). Concluding

 8 that Howell has failed to show that it was prejudiced by the district court’s failure

 9 to strictly comply with the statute, we affirm the district court’s ruling. We decline

10 to address Howell’s argument on costs.

11 I.      BACKGROUND

12   {2}   Defendant was indicted on several felony charges in connection with a

13 robbery and shooting at a diner in Milan,


 between Section 31-3-2 and Rule 5-406. See State v. Naegle, 2017-NMCA-017,
     ¶ 15, 388 P.3d 692.
                                                     12

 1 Section 31-3-2(B)’s notice provision is substantive or procedural in nature, we do

 2 not need to decide this constitutional issue.

 3 D.    Howell failed to demonstrate that it was prejudiced by the district
 4 court’s   failure to comply with Section 31-3-2(B)’s notice provision

the record, perhaps because the State informed the district court that it
                                               15

 1 was not seeking costs. Because the State declined to seek costs and because it

 2 appears that the district court awarded no costs, we reject this claim.

 3 III.     CONCLUSION

 4   {25}   We affirm the district court’s judgment.

 5   {26}   IT IS SO ORDERED.

 6


as consequent L-arginine depletion leads to impaired lymphocyte responses \[[@B21]\]. Recent studies with arginase-II knock-out mice and cell culture systems have highlighted their significance in inflammation, atherosclerosis and glucose intolerance \[[@B22]\]. However, involvement of arginases, if any, in GDM is presently elusive. Thus, the other aim of the study was to determine arginase activity and angiogenic factors in the cord blood of infants born to GDM subjects.

Materials and Methods {#s2}
=====================

MCDB 131 Basal Medium from Himedia Labs, Mumbai, India along with growth supplements was used to culture endothelial cells isolated from umbilical cords. Foetal Bovine serum of South American origin was from GIBCO, Invitrogen, NY, USA. Antibodies for flow cytometry and fibronectin were from Beckton Dickinson, USA. Arginase inhibitor (BEC hydrochloride) was from Calbiochem, Inc. La Jolla, CA. M-MuLVHUVECs at 37°C and 5% CO~2~ for 3 hours. Cells were then washed with PBS thrice to remove non-adherent leukocytes. Adhesion was assessed as the number of leukocytes adhered to HUVEC monolayer per field view. Each experiment was performed in triplicates and data are represented as mean±SEM.

RTPCR {#s2.4}
-----

Total RNA was isolated from 5 X 10^6^ cultured endothelial cells (passage P~0~) from study subjects using TRIZOL reagent (from Sigma) following manufacturer's instructions. Following DNAse treatment, total RNA (1μg) was reverse transcribed (RT) using M-MuLV RT enzyme and Oligo dT~12-18~ primers. A reaction performed in absence of reverse transcriptase enzyme acted as negative control. Amplified cDNA was subjected to PCR using gene specific primers as listed in [Table S1](#pone.0084546.s001){ref-type="supplementary-material"}. RT-PCR was also performed for GADPH as internal control.

Cord blood collection


and ELISA {#s2.5}
-------------------------------

Cord blood was collected by gently squeezing the cord and hence it was pooled from both the arteries and the vein of the umbilical cord. Collected blood was allowed to clot at room temperature. Serum was separated by centrifugation at 4000rpm for 10 minutes, and aliquots of serum were stored at −80°C until further analyses. Serum Ang-1, Ang-2, Tie-2 and VEGF concentrations were determined in duplicate by ELISA according to the manufacturer's instructions (R&D Systems, Inc., Minneapolis, MN).

Arginase activity {#s2.6}
-----------------

Arginase activity was measured according to the method described earlier \[[@B28]\]. 100 µl of serum was incubated with equal volumes of 10 mM manganese chloride in 50 mM Tris-HCl, pH 7.4 at 55°C for 10 minutes to activate the enzyme. Activated extracts were incubated with 0.1M L-arginineIn certain applications, it is desirable to limit the amount of time a signal is active in CMOS (complementary metal oxide semiconductor) circuits to protect the circuits against various circuit failure modes. One example of a circuit failure mode is a dynamic decay due to subthreshold leakage. A shift register circuit 10 is shown in FIG. 1 for the purpose of illustrating the deleterious effects of subthreshold leakage. The shift register circuit 10 is shown with only three stages for ease of understanding. Each stage comprises a pass gate 15, a dynamic storage node 35, 45 or 55 and an inverter formed by a PFET (P-channel field effect transistor) 20 and an NFET (N-channel field effect transistor) 25. A shift signal 27 and its inverse, formed by an


from negotiations on a tax bill. Only Rep. Rodney Frelinghuysen, R-11th Dist., voted yes.

Trump and GOP leaders have justified their effort to eliminate the state and local tax deduction by calling it a subsidy for high-tax states.

"Rather than people picking standard deduction or a complicated process, and everyone shifting dollars from different states and different communities, we have a simple process where instead of high tax rates, and everyone sort of subsidizing each other and trying to figure it out, why don't we lower rates for everybody, and you just pay your own," said Brady, whose state does not levy income taxes.

Statistics from the State University of New York's Rockefeller Institute of Government and the Tax Foundation refute that claim, showing that a majority of the states whoseher wedding night.

Zasteva:If we gave the Right Wing extremists Christians in the US complete power, how long do you think it would be before:

1) Homosexuality was outlawed2) Adultery was a crime3) Cohabitation was illegal4) Heresy was a crime5) Abortion & Contraception were outlawed6) Jews, Catholics, Muslims, Hindus were subject to restrictions on their ability to worship?

You know what happens when you assume?

Good thing we have a constitution which spells out such things but dont let that get in your derp fantasy when the reality of the death cult is staring you in the face.

you think so? I don't. We have farther to fall, because when have made greater advancements here, but there major difference between the comments of the patriarch of Russian's opinions about women, and those of


only time Willie has ever spoken of this much famed incident was in his 1988 autobiography Willie. In which he rationalized the incident stating "Marijuana is like sex. If I don't do it every day, I get a headache."Q:

Has anybody been able to install PyWeka?

I need to install in python 2.6 or 2.7 for windows the library PyWeka0.3dev, It says it requires setuptools, which I installed but then they told me it was a deprecated instalation library and I installed distribute, then I downloaded the PyWeka compressed package and each time I try to install it neither with setup.py nor with easy_install (where it says something like no module ez_setup). Can anybody give me a clue about how to do this?

A:

As mentioned to you via Aardvark (yes, I am omnipresent), the module in question is broken. You can't easy_install it. It's a bug in PyWeka.
You can download the file from PyPI, http://pypi.python.org/pypi/PyWeka/0.3dev, and unpack it.
In the file setup.py, remove the following two lines:
from ez_setup import use_setuptools
use_setuptools()

And


It usually occurs due to sporadic autosomal dominant mutation in the LMNA gene.\[[@ref4]\]

Case Report {#sec1-2}
===========

Two siblings, a 14-year-old male child and a 13-year-old female child, born to third-degree consanguineous parents, presented with abnormal facies and prematurely aged appearance. History from the mother revealed that the antenatal period was uneventful during both the pregnancies. Both the children were delivered at term by cesarean section and their birth weight was more than 2.75 kg. Mile stones were attained normally till 9 months of age after which growth retardation was noticed in both the children.

Height of the male and female child was 91 and 90 cm, respectively, while their weight was 11 and 10 kg, respectively. They had bird like facies with patent anterior fontanalle, frontal bossing, prominent eyes, protruding ears,peptide beta-3 is attached through two thioether linkages to cysteinyl residues 10 residues apart. This appears to be the first report of a prosthetic group covalently bound to a polypeptide through two linkages separated by such a considerable distance in the linear sequence. The visible absorption spectrum of peptide beta-3 is red-shifted by about 10 nm relative to the spectra of the other four bilin peptides. Comparison of the sequences from B-phycoerythrin to sequences of several other biliproteins has revealed the presence of a number of invariant tyrosyl and arginyl residues near bilin attachment sites.


Educational poster for use in teaching students the role of the victim, perpetrator, bystander and rescuer

Long Detail

Triangle Poster

Product Weight/Dimensions: 24 inches wide by 18 inches tall

Product Description: Using this classroom visual aid, students will consider the different roles that individuals assumed during the Holocaust and relate these roles to choices people make in contemporary society.

The European Jews, along with the other victims of the Holocaust (Communists, Socialists, political dissidents, Jehovah’s Witnesses, homosexuals, Sinti and Roma, Poles and those physically and mentally challenged) were targeted for death or discrimination by the National Socialist regime (Nazi Germany). These people were innocent victims. Depending on time and context, citizens could choose how to respond to what they saw happening around them. They could either become a perpetrator, rescuer/upstander or bystander. A/*
 * Copyright 2020 New Relic Corporation. All rights reserved.
 * SPDX-License-Identifier: Apache-2.0
 */

'use strict'

var runTests = require('./pg.common.js')

runTests('forced native', function getClient() {
  // setting env var for forcing native
  process.env.NODE_PG_FORCE_NATIVE = true
  var pg = require('pg')
  delete process.env.NODE_PG_FORCE_NATIVE
  return pg
})


research and training programs The current application will create new synergies in clinical and translational research education at The University of Iowa by bringing together a number of successful training programs, including the Graduate Program in Translational Biomedicine, the K30 Iowa Scholars in Clinical Investigation Program, the Doris Duke Clinical Research Fellowship, and a NCRR-funded K12 Program. The coalescence of these programs will result in new master's and PhD degrees in Clinical and Translational Science. In addition to bringing clinical research training under a single umbrella, the Institute will create a vibrant intellectual community of accomplished senior mentors, junior faculty, and research scholars who will undertake crossdisciplinary, cutting-edge translational research. Scholars in the degree programs will receive a core didactic curriculum with tracks in five areas of investigationa special RBF flag. This is done by setting any of the transaction's UTXO sequence numbers (which are typically set automatically), so that it's more than 0 and less than 0xffffffff-1 (4294967294).

This is accomplished simply  by adding a `sequence` variable to your UTXO inputs:
```
$ rawtxhex=$(bitcoin-cli -named createrawtransaction inputs='''[ { "txid": "'$utxo_txid'", "vout": '$utxo_vout', "sequence": 1 } ]''' outputs='''{ "'$recipient'": 0.00007658, "'$changeaddress'": 0.00000001 }''')
```
You should of course sign and send your transaction as usual:
```
$ signedtx=$(bitcoin-cli -named signrawtransactionwithwallet hexstring=$rawtxhex | jq -r '.hex')
$ bitcoin-cli -named sendrawtransaction hexstring=$signedtx
5b953a0bdfae0d11d20d195ea43ab7c31a5471d2385c258394f3bb9bb3089375
```
Now, when you look at your transaction, you should see something new: the `bip125-replaceable` line, which has always been marked `no` before, is now marked `yes`:
```
$ bitcoin-cli -named gettransaction txid=5b953a0bdfae0d11d20d195ea43ab7c31a5471d2385c258394f3bb9bb3089375


than 0xffffffff-1. (4294967294), or the same is true of unconfirmed parent transactions.

> 2. The replacement transaction pays an absolute higher fee than the sum paid by the original transactions.
> 3. The replacement transaction does not contain any new unconfirmed inputs that did not previously appear in the mempool. (Unconfirmed inputs are inputs spending outputs from currently unconfirmed transactions.)
> 4. The replacement transaction must pay for its own bandwidth in addition to the amount paid by the original transactions at or above the rate set by the node's minimum relay fee setting. For example, if the minimum relay fee is 1 satoshi/byte and the replacement transaction is 500 bytes total, then the replacement must pay a fee at least 500 satoshis higher than the sum of the originals.
> 5.can now look at your original transaction and see that it has `walletconflicts`:
```
$ bitcoin-cli -named gettransaction txid=5b953a0bdfae0d11d20d195ea43ab7c31a5471d2385c258394f3bb9bb3089375
{
  "amount": 0.00000000,
  "fee": -0.00000141,
  "confirmations": 0,
  "trusted": false,
  "txid": "5b953a0bdfae0d11d20d195ea43ab7c31a5471d2385c258394f3bb9bb3089375",
  "walletconflicts": [
    "c6de60427b28d8ec8102e49771e5d0348fc3ef6a5bf02eb864ec745105a6951b"
  ],
  "time": 1592954399,
  "timereceived": 1592954399,
  "bip125-replaceable": "yes",
  "details": [
  ],
  "hex": "02000000000101fa364ad3cbdb08dd0b83aac009a42a9ed00594acd6883d2a466699996cd69d8b01000000000100000002ea1d000000000000160014d591091b8074a2375ed9985a9c4b18efecfd416501000000000000001600146c45d3afa8762086c4bd76d8a71ac7c976e1919602473044022077007dff4df9ce75430e3065c82321dca9f6bdcfd5812f8dc0daeb957d3dfd1602203a624d4e9720a06def613eeea67fbf13ce1fb6188d3b7e780ce6e40e859f275d0121038a2702938e548eaec28feb92c7e4722042cfd1ea16bec9fc274640dc5be05ec500000000"
}
```
This represents the fact that two different transactions are both trying to use the same UTXO.

Eventually, the transaction with the larger fee should be accepted:
```
$ bitcoin-cli -named gettransaction txid=c6de60427b28d8ec8102e49771e5d0348fc3ef6a5bf02eb864ec745105a6951b
{
  "amount": 0.00000000,
  "fee": -0.00000299,
  "confirmations": 2,
  "blockhash": "0000000000000055ac4b6578d7ffb83b0eccef383ca74500b00f59ddfaa1acab",
  "blockheight": 1773266,
  "blockindex": 9,
  "blocktime": 1592955002,
  "txid": "c6de60427b28d8ec8102e49771e5d0348fc3ef6a5bf02eb864ec745105a6951b",
  "walletconflicts": [
    "5b953a0bdfae0d11d20d195ea43ab7c31a5471d2385c258394f3bb9bb3089375"
  ],
  "time": 1592954467,
  "timereceived": 1592954467,
  "bip125-replaceable":


  case WM_DESTROY:
      PostQuitMessage(0);
      break;

   default:
      return DefWindowProc(hWnd, uMsg, wParam, lParam);
   }

   return 0;
}

static struct {
   void (* draw)(void);
} graw;

struct pipe_screen *
graw_create_window_and_screen(int x,
                              int y,
                              unsigned width,
                   had, or if they did, had to work hard to gain. Millennials are mercifully devoid of the poison of nationalism that was instilled in previous generations.

Technology has set them free, and made them true citizens of the world. It has, in many ways, taken away barriers to entry too, and has meant that their creativity and imaginations are no longer limited so much by being stuck on a small rock off Europe. This is a generation without any of our baggage.

Put aside for a moment all the reasons they have to resent the legacy, economic and otherwise, we’ve left them.

In terms of potential, these kids, with much of the heavy lifting done for them, will surely create a kinder, more creative, less dysfunctional, more diverse, more tolerant, more


the fractal properties of Student’s t-distribution which is also known as Tsallis’s distribution. Like symmetric Lévians, Tsallis’s distribution has the advantage that it is steered by one clearly defined parameter $q$ only, whose numerical value for market-analysis is known to be $q=1.5$.

Our ansatz here pursues a different goal. We do not start with a differential-equation, but with the Lévy-Khintchine theorem instead. This gives us the possibility to stay as close to the Lévian structure as possible. We use the properties of the Lévy-Khintchine theorem, see e.g. the textbook by Feller [@Feller], a Markov-inequality and Lévian noise to derive a fractional distribution-function that follows from an extremal-condition for the cumulant-function. The result is a fractional Gaussian that depends on the Lévy-exponent $\alpha$ and has thus the advantage that onlyGaussian price and the fractional price can be understood by the concept of the implied volatility. We carry out a theoretical analysis of how the implied volatility would behave if market-prices would approximately behave like fractional Gaussian diffusion.

Because of it’s generality, the fractional Gaussian may certainly be applied to other problems than option-pricing, too.

Derivation of an extremal fractional Gaussian
=============================================

In this section we derive a distribution-function that has the same properties as a Lévy-distribution, but decays exponentially. The way to achieve this goal is similar to the derivation of a probability bound. The resulting probability bound, with a proper normalization, but can of course be interpreted as a distribution-function. This distribution-function is extremal, because it is a consequence of a variational procedure.

At first we shall discuss the inverse problem


understood as a generalized fractional Gaussian. To close this section, we shall note that the fractional Gaussian for $$\lim_{\alpha\rightarrow3}P(x,\,\alpha)\,=\,\vartheta[1-|x|]\quad,
\label{16}$$ converges towards the step-function. As such, our result Eq. (\[14\]) can also be understood as a distribution-function in a general sense.

Compared to an exponentially truncated Lévy-flight our approach has the advantage that it works for any numerical values of the Lévy-parameter. Conversely, exponentially truncated Lévy-flights exist only for some specific numerical values of their parametric co-dimension, see e.g. [@Paul].

Option-pricing
==============

The Black-Scholes-Merton formula for an European Call-option can easily be generalized just by inserting the fractional Gaussian Eq. (\[14\]) into the pricing-formula, where the function $G$ denotes the Greens-function of the distribution-function $P$, $$\mathcal{C}(x,\,T-t;\,\alpha)\,=\,\int_{0}^{\infty}\,dy\,\left(e^{y}\,-\,1\right)\,G(x\,-\,y,\,\sigma_{\alpha}(T-t);\,\alpha)\quad.
\label{17}$$ The time-dependency enters as a product with the variance $\sigma_{\alpha}$. The time $T$ is the time ofWhen a fault develops in a generating system, the resulting excessive load on the system caused by the fault can cause grave damage to the system as a result of overheating or other associated problems. While the problems associated with the development of faults are of concern in almost all generating systems, they may be particularly acute in the generating systems employed in aircraft having high electrical power requirements. In particular, aircraft generating systems are quite expensive in relation to their generating capacity and if damage is sustained as a result of a fault, it is commensurately more expensive to repair. Moreover, in many instances, the economical operation of aircraft depends upon a high rate of utilization of such aircraft. Consequently, excessive down time of the aircraft for


while back. Is the jurisdictional context different (re:
the 4th amendment) or is this something different to unlocking a device?

~~~
hiisukun
This is mostly requests to Apple as a service provider. "What IP registered,
and logged into suspect@icloud.com on 1/1/2018? And what are the registered
users details?"

They don't have your iphone passcode on file so they can't provide it to law
enforcement.

~~~
mikejb
This is what I thought, too, but they explicitly state "access to devices",
not "access to data".

Could also very well be that the author didn't distinct between the two
sufficiently.

~~~
DINKDINK
Or that older devices (that have outdated hardware security) are more
prevalent in Australia for which Apple can decrypt.

~~~
thisacctforreal
Would be surprising; even the iPhone 5s from Fall 2013 is equipped with the
Secure Enclave and is getting iOS 12. Including the feature to disable USB
communication pins after 1hour without the user's passcode. A feature aimed
squarely at disabling Cellebrite from uploading their brute-force firmware.

------
jlangenauer
Truly, Australia is governed by morons. Would it be asking too much for a
highly paid minister of the crown, who supposedly is supposed to lead
government policy in an area, to have substantial knowledge of it?

Instead, we have these lawyers who treat maths, science and technology with
contempt, who legislate for us, and don't understand what the fuck they're
even talking about.

~~~
afarrell
People keep saying "We need more scientists in government", but I think that
trying to make that happen is running into a brick wall: those scientists will
_also_ need to be lawyers and there just aren't that many people who are
competently both. Without an understanding of the law, they'll end up drafting
laws without basic things like mens


last thing he wants at election time is a public debate that may spin out of his control. The WikiLeaks story will eventually fade away but a legal case against American diplomats would keep the allegations of AKP corruption front and center—the same allegations that so unnerved him in the first place.("NewFilter1") will be created under your project which you can then rename as you like.
You can drag items from your project inside it in order to group them "logically" or you can right-click on your new filter and choose Add>Existing Item or Add>New Item. You can even nest multiple filters inside each other.
For example in your case, you would call this filter "Shader" and you can drag-and-drop all shader-related files inside it. This only affects your project and not the directory structure in the file system.
You can still create a "real" folder in the file system and then add files into it, which you can then reference in your project's filter.


who voted for exactly what, and writers who made some of the more absurd picks for the MVP or Cy Young awards have to try to defend those choices as best they can.
The Professional Hockey Writers' Association, however, does not publish the individual ballots of its members, and that they don't is ludicrous. This was a debate that kicked up around the end of the regular season, when some writers, in the interest of transparency and to engender discussion, said who they voted for when it came to a number of awards and often why they did so. That they were occasionally wrong in their voting is to be expected, because no one can get everything right all the time, but at least those writers in particular had  UISlider *slider = (UISlider *)sender;
    NSInteger val = lround(slider.value);
    NSLog(@"%@",[NSString stringWithFormat:@"%ld",(long)val]);
}
@end

A:

But sometimes users may want to stop the voice in the middle of the speech.

To stop speech, send the speech synthesizer a -stopSpeakingAtBoundary: message:
[self.speechSynthesizer stopSpeakingAtBoundary:AVSpeechBoundaryImmediate];

Use AVSpeechBoundaryWord instead of AVSpeechBoundaryImmediate if you want the speech to continue to the end of the current word rather than stopping instantly.
You can also pause speech instead of stopping it altogether.


capacity due to alcohol intoxication at the time. The appeals court ruled "none of his arguments . . . are persuasive."

Seattle Police homicide detective Cloyd Steiger says there was no sign of physical trauma at the jail death scene. "We suspect he died from an overdose," says Steiger. "There was no obvious physiological reason for his death." A police report notes, "There was a small spot of blood where [Hicks'] head was laying, but there was nothing else out of the ordinary." The source of the blood spot hasn't been revealed.

A King County Medical Examiner's spokesperson says an exact determination of the cause of death won't be made for six to eight weeks, pending a toxicology report. An examiner's incident report says Hicks was "heard snoring very unusuallyother post 9/11 security changes) or the cramped seats and extra fees that
come with a standard economy ticket, but not enough attention is paid to how
much safer and cheaper flying has become over the last few decades.

~~~
orbitur
When did the TSA make flying safer and cheaper?

~~~
maccard
I don't think OP is saying that TSA has affected safety or cost, merely that
flying has gotten cheaper and safer(independent of his statement about the
TSA)

------
jimbokun
"He noted that in 1960, when the jet age began, around 25 million
international trips were taken. Last year, the number was 1.3 billion."

I honestly did not expect the number to be that high.

So a double digit percentage of all humanity travels internationally, every
year.

~~~
lainga
Could be, but I think that number includes people taking multiple trips each.
Think businessmen.

~~~
newen
I really don't think it's


close to double digits. I don't even consider myself
as having travelled a lot and I've taken two international trips per year for
the last five or so years on average. There should be people who do dozens of
international trips a year but there must be a lot of people who do two or
three international trips a year.

~~~
skohan
Like a lot of things it's probably a heavily-skewed distribution. For a large
number of europeans it could be a half dozen from holidays alone. For
businesspeople in Europe it could easily be dozens of trips per year.

But there's probably huge swaths of the population who have never traveled
internationally for economic reasons, or because they live in a large country
(like China, the US, India or Russia) which makes that less necessary.

~~~
lainga
Or my relatives in Geneva,other than a few major cities in Europe!

~~~
growlist
Not sure I quite agree with this - Scotland for example is facing problems in
a number of non-urban areas due to growing tourism.

------
droidist2
Well if certain cities don't want them, I'm sure there are many places that
would love to have the boost from tourism. Maybe we'll start seeing more
tourism advertisement and viral marketing campaigns through social media (pay
a trend-setter to come to your city and vlog about it, etc.)

------
narag
"Europe" isn't worried. Some Europeans are. Some others aren't. In Barcelona
there is a three-party war between hotels, leftist council and landlords.
Council hasn't allowed to build new hotels in years, for instance.

------
distant_hat
"for a lot of people, the photos you take on a trip become more important than
the experience.”

Cheap photography is to blame for this more


summer vacation is one of society's worst inventions. It creates
so many problems in different fields, like the summer education loss.
Overtourism is just one of them.

~~~
maccard
Could you elaborate on the summer education loss? My understanding is that
grades drop across summer/fall breaks, but the (little amouht of) research
shows that shortening the breaks doesn't actually resolve the problem.

------
borkt
I've even noticed it in the California wine country. While in decades past the
weekend flow was typically from the North Bay to San Francisco, now on
weekends we regularly have traffic throughout the day in Santa Rosa.
Healdsburg, a town of around 10,000 people has added around 300 hotel rooms
this year. We are no where near tourists outnumbering locals, but it is
definitely much different than when I was a kid

------
autokad
does anyone notice how if other peopleQ:

"DNS lookup failed" Error only for few networks

I have been developing a website and hosted that website on Godaddy(VPS Hosting). My website address is http://paisamint.com, for last one week my website was working fine, but suddenly from today morning itself I'm getting "DNS LOOKUP FALILED" error only for my network( Am using Airtel India), If I user other networks like TATA Docomo and Vodafone I can able to see my website perfectly. I don't know what to do. Please help me to resolve this issue.

A:

Depends on your operating system, but did you try flushdns?


and treat disease.

CAMBRIDGE, Mass., Dec. 11, 2014 /PRNewswire/ -- To rapidly expand the use and power of genomic sequencing for diagnosing and treating rare diseases, Claritas Genomics and NextCODE Health today announced a strategic partnership bringing together global leadership in pediatric medicine and sequence analysis. Claritas Genomics, affiliated with Boston Children's Hospital, is a CLIA-certified clinical laboratory serving the DNA-based diagnostic testing needs of children's hospitals that admit hundreds of thousands of patients with genetic disorders every year. NextCODE's solutions have been developed and proven on the world's largest collection of genome sequence data.

Claritas selected NextCODE's integrated clinical and research platform after a thorough evaluation of the leading solutions in the field. NextCODE will enable Claritas to speed the delivery of genetic test results for more children andnow propose to elucidate the details of the direct intermolecular interactions between beta-catenin and androgen receptor. Our preliminary data indicate that beta-catenin binds to the AR ligand-binding domain. Moreover, LXXLL peptide motifs in the beta-catenin armadillo repeat region that resemble motifs in p160 steroid hormone coactivator molecules are important for beta-catenin/ AR interaction. Using a mammalian two-hybrid assay we will determine the regions of androgen receptor bound by beta-catenin and we will determine the regions of beta-catenin that bind androgen receptor. Using recombinant proteins we will demonstrate the direct physical interaction between AR and beta-catenin. We will also determine the ligand-dependence of this binding and the spectrum of ligands that support the interaction. We will determine if beta-catenin affects the interaction of androgen receptor with ligand by measuring


RNA was extracted from parental (C2C12) and dnp53-expressing (C2-dnp53) myoblasts ([Soddu et al. 1996](#Sodduetal1996){ref-type="bib"}) maintained in GM, or incubated in the presence of DM for different times. As expected, C2-dnp53 cells had a strong reduction in the expression of muscle structural genes, like *MyHC*, compared with the parental cells ([Fig. 2](#F2){ref-type="fig"}, a and b). A series of genes, including *MyoD*, *myogenin*, *p21^Waf1/Cip1^*, *cyclin D1* and *D3*, and *Id-1*, were found to behave similarly in the two cell types ([Fig. 2](#F2){ref-type="fig"} a). In contrast, a strong difference in the *Rb* mRNA induction was present between parental and C2-dnp53 cells ([Fig. 2](#F2){ref-type="fig"}, a and c), the latter being largely impaired in their ability to increase the *Rb* mRNA levels. This difference was even more marked at the protein level ([Fig.by indirect immunofluorescence. As shown in [Fig. 3](#F3){ref-type="fig"}, the C2-dnp53 cells that could differentiate had increased levels of pRb. Moreover, the hypophosphorylation of pRb, which is responsible for cell cycle withdrawal, was similarly present in parental and dnp53-expressing cells (data not shown), as well as in p53^+/+^ and p53^−/^− myoblasts ([Fig. 2](#F2){ref-type="fig"} e). Taken together, these results indicate that p53 is not essential for the cell cycle--related functions of pRb.

p53 Controls the Differentiation Activity of pRb
------------------------------------------------

A pRb function genetically distinct from cell cycle control affects the transcription of differentiation-related genes ([Sellers et al. 1998](#Sellersetal1998){ref-type="bib"}; [Novitch et al. 1999](#Novitchetal1999){ref-type="bib"}), pRb being required for the full function of the transcription factor MyoD during skeletal muscle differentiation ([Gu et al. 1993](#Guetal1993){ref-type="bib"}; [Novitch et al. 1996](#Novitchetal1996){ref-type="bib"}, [Novitch et al. 1999](#Novitchetal1999){ref-type="bib"}). Thus, MyoD


Genetic Expression, University of Rome La Sapienza, 00153 Rome, Italy.

*Abbreviations used in this paper:* Act D, actinomycin D; DM, differentiation-promoting medium; dnp53, dominant-negative p53; GM, growth medium; MCK, muscle creatine kinase; MSC, mouse satellite cell; MyHC, myosin heavy chain.

![p53 activity on the Rb promoter. (a) C2-P1 cells were infected with a recombinant retrovirus carrying the dnp53 gene or its insertless control. Relative luciferase activity was assessed on polyclonal populations as described in [Fig. 5](#F5){ref-type="fig"}. (b) C2C12 cells were stably transduced with pXRP1 (C2-P1), pd92 (C2-d92), and pXRP1-mtp53 (C2-P1mtp53). Relative luciferase activity was assessed on polyclonal populations as in a. (c and d) Cross-linked chromatin from the indicated cells was immunoprecipitated with antibodies to p53, Sp1, or in the absence of antibodies, and analyzed by PCR with primers specificMix1 and C2-P1 Mix2) were incubated as in a. Columns report the luciferase activity of each cell line, relative to its own GM. (c) The region between −219 and −143 base-pairs upstream of the translation start site of the C2C12 endogenous *Rb* promoter was analyzed by in vivo footprinting in proliferating (P) and 48 h differentiated (D) cells; in vitro footprinting (V) was used as control. (Continuous arrows) Bands that are significantly protected; (dashed arrows) bands that are not protected; and (\*) spurious bands. (d) Total RNA was extracted from C2C12 and C2-dnp53 cells maintained in GM or DM for 48 h, with or without Act D. Northern blottings were performed for the *Rb* and *GAPDH* genes. Histograms show quantitative analyses of the *Rb* gene expression levels relative


and $a_1$. Very impressively, if the initial electron (or both electron and positron) is polarized, one may use the polarization asymmetrized distribution. The distribution is defined as the differential cross section difference between two different polarizations. With this method, a $d_\tau $ as small as $10^{-19}$ e-cm can be reached at TCF [@Ana], this corresponds to a sensitivity of $10^{-5}$ of CP/T violation. Up to now the best experimental bound on $d_\tau $ is from LEP experimental data, which is used to exclude indirectly the $d_\tau $ as large as $10^{-17} $ e-cm [@ALE], so two order of magnitudes improvement on $d_\tau $ measurement can be achieved at TCF.

Besides the CP/T-odd operator method, several other useful strategy were proposed to test these violation in $\tau $ decay. 1). If $V$ is at TeV scale $d_l$ is smaller than $10^{-20}$ e-cm. Although, in principle, $d_\tau $ is possibly as large as $10^{-19}$e-cm , one has to avoid too large EDM of electron $d_e$ at the same time. Current experimental upper limit on $d_e$ is about $10^{-26}$e-cm. This is a very strong constraint especially when one is expecting large $d_\tau $. So in any beyond standard model, two requirements must be satisfied in order to obtain measurable $d_\tau $. The first one is that the model must provide $d_\tau $ at one loop level and $d_\tau $ is not suppressed by a small fermion mass term, the fermion mass term should be a top quark mass, supersymmetric partner of bosons or other exotic fermion masses. The second


decay modes, because of the uncertainty in the hadronic matrix elements. On the other hand, for the inclusive cases, one may make a more reliable quantitative estimation due to the fact that one has no need to deal with the hadronization of quarks in this case. In addition, QCD correction should not change the order of the tree level diagram evaluation as the energy scale for $\tau $ decay processes is around 1GeV. In this section we only deal with the diagrams containing quark pair inclusively, So the CP/T violation size we estimate below is for all the possible hadronic decay channels. In the last section we will comment on our results in exclusive processes. Because of the scale of $\tau $ mass, its decay products can only^2}{M_H^2}Im(ZZ^{*})\leq 2\times
10^{-2}. \end{aligned}$$ Here the additional factor $\frac{m_\mu }{m_\tau }$ comes from the interference of left- and right-handed muon lines in the final states. So we expect that CP/T violation effect in the process $\tau \to e\nu {\bar \nu }$ is suppressed by a factor $m_e/m_\mu $ and is negligible. For the hadronic decay $\tau \to {\bar u}d\nu $ we have $$\begin{aligned}
\epsilon \simeq \frac 12\frac{m_d{\bar m}_d}{M_H^2}Im(XZ^{*})\leq 3\times
10^{-4}, \end{aligned}$$ With the current $d$ quark mass $m_d=7$ MeV and the dynamical $d$ quark mass ${\bar m}_d=300$ MeV . For hadronic decay $\tau \to {\bar u}s\nu $ similar result is obtained $$\begin{aligned}
\epsilon \simeq \frac 12\frac{m_s{\bar m}_s}{M_H^2}Im(XZ^{*})\leq 1.5\times
10^{-3} \end{aligned}$$ Here we use current and dynamical $s$ quark masses as 150 MeV and 400 MeV respectively. In summary, in multi-Higgs doublet model CP/T


violation effect is possibly as large as order of $10^{-3}$ for exclusive hadronic decays and It could be even close to $10^{-2}$ in pure leptonic decay to $\mu $ and neutrinos.

[**Other extensions of the SM for pure leptonic decays**]{} Besides leptoquark and Higgs doublet, there are three other kind of scalars which can couple to leptons. We denote $l$ as a lepton doublet and $E$ as a singlet lepton. Two $l$ can combine to a charged singlet or a triplet. Two $E $ can combine to a double charged singlet. Corresponding to these three cases one can introduce a charged singlet scalar $h^{-}$, triplet scalar $\Delta $ and double charged scalar $K^{--}$. However $K^{--}$ only induce a lepton family- number-violating process $\tau \to 3l$. There is no diagramand LEP II experiments. It is interesting to see if the new particles predicted by the various models we have discussed in this paper are indeed detectable in these high energy experiments. (5) Precise measurement of the pure leptonic decay is another way to test the new physics responsible for CP/T violation. Since if there is CP/T violation effect at level of $10^{-3}$, the $\tau $ leptonic decay width must deviate from the SM prediction at the same level. So we expect to observe the deviation by measuring the branching ratio of the pure leptonic decay. However it is not true [*vice versa*]{}, since a deviation of leptonic branching ratio from that of the SM does not necessarily indicate CP/T violation.

Finally we come to our conclusion. There exists


21-23 91995) P89.

ALEPH Collaboration, Phys. Lett. B281, 405 (1992); 459 (1992).

ALEPH Collaboration, Phys. Lett. B272, 411 (1991); R. Escribano and E. Masso, Phys. Lett. B301, 419 (1993).

W. Bernreuther and O. Nachtmann, Phys. Rev. Lett. 63, 2787 (1989); Phys. Rev. D 48, 78 (1993); W. Bernreuther and O. Natchmann, G. W. Botz and P. Overmann, Z. Phys. C52, 567 (1991).

B. Ananthanarayan, S. D. Rindani, Phys. Rev. D51, 5966 (1995); Phys. Rev. D 50, 4447 (1994); Phys. Rev. Lett. 73, 1215 (1994).

C. A. Nelson, Phys. Rev. D41, 2805 (1990); D43, 1465 (1991); D50, 4544 (1994).

S. Goozovat and C. A. Nelson, Phys. Lett. B267, 128 (1991).

Y. S. Tsai, Phys. Rev. D51, 3172 (1995).

Y. S. Tsai, preprint NO. SLAC-PUB-7124, 1996; proceedings of Workshop on the Tau/Charm Factory, Argonne, June 21-23 (1995), P104.

S.result.

J. F. Nieves, D. Chang and B. Pal, Phys. Rev. D 33, 3324 (1986).

J. Donoghue and B. Holstein, Phys. Lett. B113, 382 (1982); I. L. Bigi and J. M. Frere, Phys. Lett. B 110, 255 (1982).

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G.B. Gelmini and M. Roncadelli, Phys. Lett. B 99, 411 (1981).


t.* *holarctica* in aquatic habitats, via transstadial maintenance in mosquitoes, and transmission to susceptible mammals. The bacteria are associated with the mosquito in a passive, non-replicating quiescent state, and are resuscitated upon contact with the mammalian host, a process which represents a novel transmission cycle for a bacterial pathogen.

Methods
=======

Mosquito breeding and exposure of mosquito larvae to *F. t. holarctica*
-----------------------------------------------------------------------

Eggs of the tropical mosquito *Ae. aegypti*, kindly provided by Oxitec (Oxitec LTD, Oxford, England), were hatched in deionized water. Larvae, approximately twenty per container (Mosquito Breeder, BioQuip Products, Rancho Dominguez, CA, USA), were maintained in tap-water at room temperature (RT) and fed crushed fish flakes. *F. t. holarctica* strain FSC 200[@b30] was grown on modified Thayer-Martin agar plates[@b31] at 37°C in 5% CO~2~. Mosquito larvae were exposed to *F.(Bio-Rad). To test the limit of detection and generate a standard curve for assessing target DNA concentrations, mosquito homogenates spiked with *F. t. holarctica* concentrations ranging from 5 × 10^1^ to 5 × 10^5^ cfu per ml were analyzed, in triplicates.

Mouse model
-----------

The mosquito homogenates that tested positive for *F. tularensis* DNA in the preliminary PCR screen were pooled before being used to infect mice to test for the viability and virulence of any *F. t. holarctica* present in the samples. Three to five homogenates were pooled to form seven pools ranging in volume from 250 μl to 300 μl. The seven pools were injected intra peritoneally (i.p.) into eight mice (200 μl/mouse), pool one being divided and injected into two different mice (120 μl each). Four pools of mosquito homogenates from unexposed mosquitoes


To: Costa, Kristina >> > Subject: Fw: Hey there, and a quick heads up >> > >> > >> > ----- >> > From: Eilperin, Juliet [mailto:Juliet.Eilperin@washpost.com] >> > Sent: Saturday, March 21, 2015 07:24 PM >> > To: Benenati, Frank >> > Subject: FW: Hey there, and a quick heads up >> > >> > Dear Frank, >> > Nice to see you last night, I hope you had fun. I sent this note to Eryn yesterday, I just wanted to make sure John Podesta had a heads up that his name will be in a story concerning the White House's ethics policy, which could run on Monday. I don't mention anything specific about the Wyss contract (since I never got a response from you on it),       = %% BslClient.Client.goto %%: string -> void
  alert           = %% BslClient.Client.alert %%: string -> void
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   * This function is deprecated, and does not belong to this module
   * WARNING : return -1 if the event doesn't contains a keyCode!!!
   * TODO : Remove it (beware some applications use it, triptizer, etc...)
   */
  get_keycode(event : Dom.event) =
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the sky. And that you really get close to danger and this is not like slightly close to danger, this is really close to danger*.

The metaphor is derived from the Greek myth of Icarus who escapes imprisonment, yet fails because in his flight he ventures too close to the sun. As a result, the wax of his wings begin to melt so that he ultimately falls and dies. The Icarus metaphor vividly illustrates women\'s need for challenge but also a duality of emotions they experience in their drive to achieve career success. On the one hand, there is excitement and a sense of empowerment, on the other hand, they experience anxiety and doubt. The metaphoric scenario is the context of escaping imprisonment, which potentially represents breaking free fromonto him) and how the woman identifies (introjection) with the good and preferred characteristic of being non-judgemental. The projection of badness and participants\' response to it, represents women\'s expressed need to be accepted and not be judged:

> *Central to the dream is something I believe very strongly in. One shouldn\'t judge. I feel there are people in my house that are terribly judgemental. Just like that, judge, judge, judge, and it\'s something I\'ve felt my whole life: I can\'t judge others. I just immediately felt this guy, maybe from ISIS or whatever, I can\'t judge him*.

Attempting to maintain a personal identity of competence, women find it challenging to reconcile a competent self with stereotypic gendered expectations of performing inferior work. Confirming this dynamic is another dream in which


conflicting expectations between their personal and social identities, women frequently assess their self-worth through constant interpersonal comparison. This is typical to conceptual definitions of identity work (Adams and Crafford, [@B2]). Participants attested that they frequently were negotiating who they are (personal identity) in comparison to others and others\' expectations for them (social identity). Reflecting on her interaction with a group of young adult women at a wedding, a participant stated:

> *I wish I was as sorted out as they are at that age ... they know what they want and how and what; this girl is 24 and she knows exactly what she wants. I mean, when I was 24 everything was confused and then I think: 'Wow! I am actually not even where she is now.' Shecareer life stages. The focus was rather on the psycho-social dynamics at play when these women deal with their need for challenge, balance, and authenticity to sustain their well-being in work and life.

Regarding the need for *challenge*, well-being is evidenced in women\'s need for purpose and self-optimisation. However, at the same time, their well-being is challenged by introjections of self-doubt and anxiety, which participants described. These impediments arise from their struggle with internally entrenched gendered stereotypes and identification with masculine norms of success. Women\'s need for challenge is paralleled by their psycho-social need for belonging, the latter prompting projective identification with gendered expectations about career success and achievement. This detrimental identification is thus exacerbated by a conflicting dynamic that underpins the women\'s fundamental psycho-social needs. These needs are