Then I’m looking for the magazine left by the murderer on her lap and opened at an article about someone in her circle of friends.”

He said he was willing to pay for evidence to be sent to an American lab for forensic testing. He said police had told him that evidence had disappeared after being removed from a judge’s office.

Lotz said there was nothing left for him but to search for justice for his child. “Before I die, that is the least I can do for her. No amount of money is too much for this.”

“I will never have peace if I don’t know who committed this terrible crime.”

Lotz family flooded with calls after reward offeredMarch 20 2012 at 03:37pm By Zara Nicholson

Numerous calls have been received byBushy Engelbrecht, another celebrated senior former policeman.

According to his CV, Engelbrecht has supervised numerous high profile investigations, including the politically motivated Shobashobane massacres in Port Shepstone and the Richmond (KZN) killings.

Lotz, speaking at his home in Welgemoed, told the Cape Argus: “I put a million rand on the table, and I needed probably the best I could find. In my mind, I could not have found a better man than Piet Byleveld.”

Lotz put up the money about 10 days ago for anyone who could help in catching his daughter’s killer.

Asked by the Cape Argus whether he had concerns about his or his wife’s personal safety by offering the massive reward, he told the Cape Argus recently: “So be it. Without this knowledge, my life is nothing. It’s not


players "think Upshaw's successor should be a former player, as Upshaw was." Miller, who served as an NFLPA player rep for the Browns, sent an e-mail to current player reps indicating that he was "officially campaigning for the job." Miller: "I am running." Sources said that former NFLPA Presidents Trace Armstrong and Troy Vincent, as well as former exec committee member Robert Smith, "continue to be considered leading player candidates." Meanwhile, NFLPA outside counsel Jeffrey Kessler, NFL Exec VP/Football Operations Ray Anderson, former NFLPA Assistant Exec Dir Doug Allen, who now serves as Screen Actors Guild Exec Dir, and MLBPA Associate Counsel Mike Weiner have all "said that they will not pursue the job" (SPORTSBUSINESS JOURNAL, 9/15 issue). Vincent said that he "would not comment on whether hewill seek Upshaw's position until the players 'believe I am a viable candidate'" (SPORTSBUSINESS JOURNAL, 9/15 issue).

Miller Only Candidate Openly
Campaigning For Position

LINEBACKER BLITZ: In a special to THE DAILY, Mullen reports Miller has unveiled a political platform which includes the union opening an entertainment office in L.A. as part of his bid to succeed Upshaw. Miller said that out of the proposed new L.A. office, “The NFLPA will seek to create its own programming for TV, film, the web, or any other appropriate medium, working with established entertainment entities.” Miller also proposed a mentor program and new financial and health plans for the union. A number of players and others in sports are believed to be seeking the position that Upshaw held for 25 years before his unexpected


help me on this?
public class todoFragment extends ListFragment{

private EditText mToDoField;
private Button mAdd;
UsersAdapter mAdapter;
private TextView todoTextView;
private CheckBox todoCheckBox;

@Override
public void onCreate(Bundle savedInstanceState) {
    super.onCreate(savedInstanceState);
    getActivity().setTitle(R.string.todo_title);
}

public class UsersAdapter extends ArrayAdapter<String> implements View.OnClickListener{

    public Context context;
    public ArrayList<String> values;

    public UsersAdapter(Context context, ArrayList<String> values) {
        super(context, 0, values);

        this.context = context;
        this.values = values;
    }

   @Override
    public void onClick(View view) {

        todoCheckBox.setOnClickListener(this);

        if (todoCheckBox.isChecked()){
          the parameter-ellipticity of ${\widetilde}{a}$. Clearly implies boundedness with respect to $\lambda\in\Lambda$ of $$[\lambda](\lambda-{\widetilde}{a}(x,\xi))^{-1}\;\in\;S^{0,0}_{{\mathrm{cl}}(x)},\qquad
   (\lambda-{\widetilde}{a}(x,\xi))^{-1}\;\in\;S^{-\mu,0}_{{\mathrm{cl}}(x)}.$$

Using integration by parts and choosing $k>1+\frac{n+1}{\mu}$, we have $$\label{zero3.C}
 \operatorname{TR}e^{-tA}=t^{-k}\frac{(-1)^{k}k!}{2\pi i}\int_{\partial\Lambda}e^{-t\lambda}\,
 \operatorname{TR}(\lambda-A)^{-k-1}\,d\lambda;$$ in fact, by Proposition \[zero3.2\], we know that the symbol of $[\lambda]^{2}(\lambda-A)^{-k}$ belongs to the space $S^{-n-1,0}_{{\mathrm{cl}}(x)}$, uniformly in $\lambda$. Hence, the continuity of the trace functional allows to pull $\operatorname{TR}$ under the integral. Due to the holomorphicity of the integrand, we can modify the path of integration, $\partial\Lambda$, to a parametrization of the boundary of $\Lambda\cup\{|\lambda|\le{\varepsilon}\}$ for sufficiently small ${\varepsilon}>0$. We shall use this fact frequently without indicating it explicitly.

[From]{} it follows that $\operatorname{TR}e^{-tA}$ is holomorphic in a sector of the form $\{t=re^{i\varphi}{\mbox{\boldmath$\;|\;$\unboldmath}}r>0,\,|\varphi|<\theta_0\}$ for $0<\theta_0\le \pi/2-\theta$, decays there exponentially for $|t|\to\infty$, and when $|t|\to0$ it is $O(|t|^{-k})$ for


transition maps $\kappa_{jk}\kappa_{jl}^{-1}$ are of the form $\Phi: x\mapsto |x|\varphi(x/|x|)$ with a diffeomorphism $\varphi$ of the corresponding open subsets of $\mathbb S^{n-1}$. They thus satisfy the relation $$\begin{aligned}
\label{chco}
\Phi(\lambda x ) = \lambda \Phi(x), \quad\lambda\ge 1.\end{aligned}$$

We can then introduce the spaces $\mathcal S(\mathcal M)$ and $\mathcal S(\mathcal M\times\mathcal M)$ of rapidly decreasing functions on $\mathcal M$ and $\mathcal M\times\mathcal M$, respectively. We call an operator $R: {\mathcal{C}^\infty_{\text{\rm comp}}}(\mathcal M)\to {\mathcal C}^\infty(\mathcal M)$ regularizing, provided that its integral kernel with respect to the above coordinates is in $\mathcal S(\mathcal M\times\mathcal M).$

On each $E_j$, we introduce a special partition of unity: We pick a partition of unity $\{\psi_{jk}\}$ on $C_j$, subordinate to the cover $C_{jk}$, and define $\{\tilde\psi_{jk}\}$ on $E_j$ by $\tilde \psi_{jk}(x) = \psi_{jk}(x/|x|)$. Similarly we choose functions $\eta_{jk}\in {\mathcal{C}^\infty_{\text{\rma local coordinate $x$ on an end with $|x|\le R$. The special form of the changes of coordinates along the ends makes well-defined. It follows from the considerations in Section \[sec:zero1.2\] that this coincides with the previous definition for the case $\mathcal M={{\mathbb R}}^n$.

Appendix:  SG-pseudodifferential Operators, Parameter-ellipticity, and Complex Powers {#sec:zero5}
=====================================================================================

The calculus of classical SG-pseudodifferential operators has been developed by Hirschmann [@Hirs]. We summarize here the basic results including material on parameter-ellipticity, resolvent, and complex powers. For details we refer the reader to [@MSS] and [@EgSc].

In the sequel, let $[\,\cdot\,]$ denote a smooth, positive function on ${{\mathbb R}}^n$ that coincides with the Euclidean norm outside the unit ball.

Symbols with Values in a Fréchet Space {#sec:zero5.0}
--------------------------------------

Let $E$ be a Fréchet space and $\nu\in{{\mathbb R}}$. By definition, $S^{(\nu)}({{\mathbb R}}^n,E)$ is


k\ge1.$$ Then there exists a symbol $b(x,\xi,\lambda)$ such that

-   for any $N\in{{\mathbb N}}_0$ and all $\alpha,\beta\in{{\mathbb N}}_0^q$ $$\Big|\partial^\alpha_\xi\partial^\beta_x\Big(b(x,\xi,\lambda)-
         \sum_{k=0}^{N-1}b_{-k}(x,\xi,\lambda)\Big)\Big|
         \le
         C\,(|\lambda|+{[x]}^m{[\xi]}^\mu)^{-1}{[x]}^{-N-|\beta|}
         {[\xi]}^{-N-|\alpha|},$$ uniformly for $x,\xi\in{{\mathbb R}}^n$ and $\lambda\in\Lambda$,

-   $|\lambda|^2\big\{(\lambda-a(x,D))^{-1}-b(x,D,\lambda)\big\}\in
      S^{-\infty,-\infty}$ uniformly for large $\lambda\in\Lambda$.

For a classical symbol $a$ $\Lambda$-ellipticity can be characterized by spectral properties of the associated homogeneous principal symbols:

\[rem:ell-classical\] Let $a\in S^{\mu,m}_{\mathrm{cl}}$. Then $a$ is $\Lambda$-elliptic if, and only if,

-   $\text{\rm spec}(a^{(\mu)}(x,\omega))\cap\Lambda=\emptyset$ for all $x\in{{\mathbb R}}^n$ and $|\omega|=1$,

-   $\text{\rm spec}(a_{(m)}(\theta,\xi))\cap\Lambda=\emptyset$ for all $\xi\in{{\mathbb R}}^n$ and $|\theta|=1$, and

-  $n_{k+1}-n_k$ summands of $a_{n_k}$.
That leads to the inequality I hinted at in my comment for any integer $s \ge 1$:
$$\sum_{k=n_1}^{n_s-1} a_k \le \sum_{k=1}^{s-1}(n_{k+1}-n_k)a_{n_k} \tag2 \label{eqrueck}$$
because the right hand sum replaces each block $\underbrace {a_{n_k} + a_{n_k+1} + \ldots + a_{n_{k+1}-1}}_{n_{k+1}-n_k \text{ terms}}$ from the left hand sum with a block $\underbrace{a_{n_k} + a_{n_k} + \ldots + a_{n_k}}_{n_{k+1}-n_k \text{ terms}}$, which is at least as big. The latter follows from the $(a_n)$ sequence being monotonically decreasing.
Since all involved summands are positive, because of \eqref{pos}, the boundedness of the partial sums is equivalent for the sums to converge. So from \eqref{eqrueck} the $\Longleftarrow$ of the equivalence follows immediately, as the right hand side of \eqref{eqrueck} is then bounded by finite $\sum_{k=1}^{\infty} (n_{k+1}-n_k)a_{n_k}$, so arbitrarily long partial sums of $\sum_{n=1}^{\infty} a_n$


is a member of Magnolia Square Homeowners Association (MSHA).
*1054 Safeco Insurance Company provided coverage for MSHA under an all-risk property insurance policy. The coverage commenced on September 1, 1979, and was renewed on an annual basis until September 1, 1986.
In early 1978, Magnolia Square experienced extensive water leakage problems and began negotiating with the developer of the complex regarding repairs. In 1981, MSHA retained Walter Gloskowski, a civil engineer, to examine the building for possible construction defects. Gloskowski's report documented several problems including (1) absence of building paper; (2) improper flashings; (3) electrical problems; (4) improper nailing; (5) absence of caulking and (6) other violations of the building codes. The report also noted, "There are likely other adverse conditions which a more complete and technically exhaustive inspection mightleakage and that such damage is severable from damage to the Magnolia Square structure. (Cf. Winston Square Homeowner's Assn. v. Centex West, Inc. (1989) 213 Cal. App.3d 282, 289 [261 Cal. Rptr. 605].) Although separate areas of damage may exist in a case like this, the 1985 complaint was not limited to damage attributable to water leakage. The complaint contained an express subheading titled "STRUCTURAL DEFECTS" under which specific structural problems, including the fact that certain components were missing or inadequate, were listed. Such damage is not attributable to water leakage and thus cannot persuade us that MSHA had no knowledge of structural problems prior to May 1986.
In sum, we conclude that the allegations of MSHA's 1985 first amended complaint demonstrate that the loss occurred no later than


Nilambur/Kalpetta, Kerala: A young man who has lost all six remaining members of his family, a trader who has lost his source of livelihood, a salesman whose house has been completely swept away by a stream: these are some of the people at the panchayat in Pothukal, a village located near the Western Ghats. On August 8, as heavy rains hit the region, parts of a huge mountain collapsed over the village, burying more than 50 people alive.

After six more bodies were recovered on Sunday, the death toll reached 46. The other 13 are still missing under the mud, rocks and trees unleashed by the landslides. The search operations conducted jointly by the state police, fire and rescue services, NDRF and civilian volunteers continue.

However, even the efforts ofDonald Trump's rise Trump, center, stands at attention during his senior year at the New York Military Academy in 1964. Hide Caption 4 of 37 Photos: Donald Trump's rise Trump, center, wears a baseball uniform at the New York Military Academy in 1964. After he graduated from the boarding school, he went to college. He started at Fordham University before transferring and later graduating from the Wharton School, the University of Pennsylvania's business school. Hide Caption 5 of 37 Photos: Donald Trump's rise Trump stands with Alfred Eisenpreis, New York's economic development administrator, in 1976 while they look at a sketch of a new 1,400-room renovation project of the Commodore Hotel. After graduating college in 1968, Trump worked with his father on developments in Queens and Brooklyn before


Cobras Cobras Cobras, Balacade, Almonds, Cohen and Dreamboat all have CDs available directly from the bands, so get out to their shows or send out some e-mails and get your hands on some great local music.

-

P.S. My computer crashed this week, so this post is not all it was intended to be. Soon you will be able to download the interview with Cody and also listen to the compilation off this page. Stay tuned!

-

On Sunday, August 12 Troy Lemberg will be filling in for my show as I will be in Toronto for the weekend. The regular programme should continue the following weekend.Introduction {#Sec1}
============

Colorectal cancer (CRC) is the second most common cause of cancer death in Europe.^[@CR1]^ Although survival has improved, this is predominantly a result of better surgical technique and adjuvant/neo-adjuvant therapies. Despite this, 5-year survival remains poor, at 60%, across all stages of the disease.^[@CR2]^ The present TNM-based staging of CRC is suboptimal, given the heterogeneity in survival among patients across the same stage of disease. There is an obvious clinical need to identify characteristics pertaining to both the tumour and the host, which may not only guide prognosis, but also novel adjuvant therapies.

BRAF V600E mutations are currently being investigated as a predictive biomarker for selecting patients for EGFR inhibitor treatment.^[@CR3]^ BRAF mutations exhibit different associations with prognosis depending on the subset of CRC patients. In sporadic CRC,


patients with mismatch repair (MMR)-deficient (dMMR) tumours harbouring BRAF mutations have an improved survival. Conversely, in MMR-competent (cMMR) patients, BRAF mutations convey a poor prognosis and their prognosis declines further in BRAF mutant metastatic disease.^[@CR4]^ Furthermore, dMMR/BRAF mutant patients have a 5-year survival rate of 65% compared to 46% for cMMR/BRAF mutant patients. The reason for this difference in survival of BRAF mutant patients is still unclear, but may lie in the expression of downstream targets, such as extracellular regulated kinase (ERK).

ERK is part of the mitogen-activated protein kinase (MAPK) family along with two other members, p38MAPK and c-Jun-regulated kinase (JNK). All MAPKs are serine--threonine kinases activated by dual phosphorylation. The effects of MAPKs on patient survival in various cancers are varied,^[@CR5]--[@CR8]^ with some studies showing a survivalBRAF mutant patients, the combined nuclear pERK/p-p38 score was assessed for effects pertaining to MMR status (Fig. [2](#Fig2){ref-type="fig"}). In cMMR patients, a both strong combined nuclear pERK/p-p38 score improved CSS (HR 0.49 95% CI 0.27--0.89, *p* = 0.016). Whereas in MMR-deficient patients, a both strong combined pERK/p-p38 score did not significantly improve patient survival (HR 0.45 95% CI 0.08--2.16, *p* = 0.285).Fig. 1Combined nuclear pERK/p-p38 score stratifies CSS in BRAF mutant CRC patients (*n* = 782). Kaplan--Meier curves showing associations between (**a**) pERK or (**b**) the combined nuclear pERK/p-p38 score and CSS in BRAF WT and BRAF mutant patients with CRCFig. 2Combined nuclear pERK/p-p38 score differentially stratifies BRAF mutant CRC patient survival in MMR-competent and MMR-deficient patients (*n* = 165). Kaplan--Meier curves showing association between the combined nuclear pERK/p-p38 score and CSS in BRAF mutant patients with


in these patients. To confirm the utility of this prognostic marker across all disease stages of CRC, we next stratified cMMR BRAF mutant patients by stages, and found that this survival advantage with the nuclear ERK/p38 score was potentiated in patients with stage III CRC. Patients with a both weak/one strong score had significantly poorer survival rates. In contrast, the survival difference previously observed was lost in stage I/II patients. These finding suggest that BRAF mutational analysis should be extended beyond it's current clinical application in metastatic disease to the adjuvant setting to further aid clinicians with patient prognosis.

In conclusion, this is the first study to show a combined survival advantage of ERK and p38MAPK in cMMR BRAF mutant patients with stage III CRC; confirmation in an independentHugh Fraser Non-Clinical Lecturer in Surgery Fellowship and The Royal College of Physicians and Surgeons of Glasgow Ritchie Trust Fellowship supported this work.

Competing interests {#FPar2}
===================

The authors declare no competing interests.

Ethics approval {#FPar3}
===============

Ethical approval was obtained from the West of Scotland Research Ethics Committee for use of surplus tissue (16WS0207) and was performed in accordance with the Declaration of Helsinki.

Availability of data and material {#FPar92}
=================================

All clinical information is held within a database available from the NHS GGC Safehaven, and tissue microarrays are available from the NHS Research Scotland GGC Biorepository.


One of the more serious problems of electrodialysis stacks is the leakage of liquid from the various compartments. Attempts made include the provision of units of anion-specific membrane, spacer and cation specific membrane in the form of a sealed bag, provided with outlet means. A plurality of such consecutive bags, separated from each other by spacers, and arranged in a suitable housing, with terminal electrode compartments, have been in use for some time. The present invention provides modular units which can be easily assembled, which can be exchanged for new ones if some fault develops, and which overcome the shortcomings of leakage and the like.a nuclear weapons state and its military expenditure ranks fourth or fifth in the world. The UK has been a permanent member of the United Nations Security Council since its first session in 1946 and it has been a leading member state of the EU and its predecessor, the European Economic Community, since 1973. However, on 23 June 2016, a referendum on the UKs membership of the EU resulted in a decision to leave. The Acts of Union 1800 united the Kingdom of Great Britain, Scotland, Wales and Northern Ireland have devolved self-government

2.
1900 in Ireland
–
Events from the year 1900 in Ireland. 16 January — Three lion cubs reared by an Irish red setter go on view at Dublin Zoo,17 January — The different sections of the Nationalist Party


series of defeats on the Royal Navy, which was short on manpower due to the conflict in Europe

5.
Monarchy of the United Kingdom
–
The monarchy of the United Kingdom, commonly referred to as the British monarchy, is the constitutional monarchy of the United Kingdom, its dependencies and its overseas territories. The monarchs title is King or Queen, the current monarch and head of state, Queen Elizabeth II, ascended the throne on the death of her father, King George VI, on 6 February 1952. The monarch and his or her immediate family undertake various official, ceremonial, diplomatic, as the monarchy is constitutional, the monarch is limited to non-partisan functions such as bestowing honours and appointing the Prime Minister. The monarch is, by tradition, commander-in-chief of the British Armed Forces, from 1603,on the floor of the dock in accordance with the docking plan of the ship. Routine use of dry docks is for the graving i. e. the cleaning, removal of barnacles and rust, some fine-tuning of the ships position can be done by divers while there is still some water left to manoeuvre it about

12.
Pembroke Dock
–
Pembroke Dock is a community and a town in Pembrokeshire, South West Wales, lying north of Pembroke on the River Cleddau. Originally a small fishing village known as Paterchurch, the town was expanded from 1814 onwards following the construction of a Royal Naval Dockyard. It is the third largest town in Pembrokeshire after Haverfordwest and Milford Haven, from the 790s until the Norman Invasion in 1066, the Milford Haven estuary was used occasionally


Franschhoek. The influence of small body of immigrants on the character of the Dutch settlers was marked. The Company in 1701 directed that only Dutch should be taught in the schools and this resulted in the Huguenots assimilating by the middle of the 18th century, with a loss to the community in the use and knowledge of French. The little settlement gradually spread eastwards, and in 1754 the country as far as Algoa Bay was included in the colony, at this time the European colonists numbered eight to ten thousand. They possessed numerous slaves, grew wheat in sufficient quantity to make it a commodity crop for export, but their chief wealth was in cattle. Through the latter half of the 17th and the whole of the 18th century,6 January 1900 the Boer forces of Commandant-General Piet Joubert attempted to end the siege by taking the town before the British could launch another attempt to break the siege and this led to the battle of Platrand south of the town. Buller finally broke the siege on 28 February 1900 after defeating the Boers by using close cooperation between his infantry and artillery. Sir Winston Churchill, then a war correspondent for The Morning Post, was present at the Relief of Ladysmith after having been taken prisoner. Mohandas Gandhi and the corps that he established earlier during the war was involved in a number of actions that took place in. Ladysmith is located on the banks of the Klip River, with the business district. It is on the


the desire to escape from British authority. When Boer families first reached the area discovered that it had been devastated by a section of the Zulu tribe under Mzilikazi and his people. The Matebele had swept the country, destroying the fields, carrying off the cattle, the Boers soon came into collision with Mzilikazis raiding parties, which attacked Boer hunters who crossed the Vaal River. Reprisals followed, and in November 1837 the Boers decisively defeated Mzilikazi, in the meantime another party of Cape Dutch emigrants had settled at Thaba Nchu, where the Wesleyans had a mission station for the Barolong. The emigrants were treated with kindness by Moroka II, the chief of that tribe. In December 1836 the emigrants beyond the Orange drew up in general assembly an elementarybox

35.
Rallying
–
Rallying is a form of motorsport that takes place on public or private roads with modified production or specially built road-legal cars. Rallies may be won by pure speed within the stages or alternatively by driving to a predetermined ideal journey time within the stages, the term rally, as a branch of motorsport, probably dates from the first Monte Carlo Rally of January 1911. Until the late 1920s, few if any other used the term. The first of these races was the Paris–Bordeaux–Paris race of June 1895, won by Paul Koechlin in a Peugeot. Levassors time for the 1,178 km course, running virtually without a break, was 48 hours and 48 minutes, an average speed of 24 km/h. Speeds had now far outstripped the safe limits of dusty


recently got a cutting machine and I’m having so much fun exploring it. Something I have always wanted to make with my cutting machine is flowers! I have seen so many beautiful creations made with flowers and I thought adding some paper flowers to an Easter basket would look so beautiful! Then to top it off, add some beautiful pastel colored candy to add more to the decor. I loved the colors in the Mars Chocolate Spring Mixed Minis Bags! They are great for decorating your Easter basket and filling Easter eggs. Plus you get to enjoy all of your favorite candy in one bag! A little variety for everyone! You can buy your large bag of yummies at your local Sams Club! Hover over the image belowthe pieces of the flower out by hand.

Since I have a cutting machine at my house I cut each template out with a different colored piece of paper. Once everything was cut I started to assemble the flowers. Each petal you will want to crisscross the petal at the cut. On the larger petals, you will want to do a smaller cross as you want them to lay more flat. The smaller petals you cross at the bottom of the petal a little more. This way it will stand up more in the center of the flower. Add a dot of glue (I used a hot glue gun) to glue the two pieces together.

After they are dry then add a dot to your base of the flower. Add


We are a tight knit community of like minded enthusiasts who value "on topic", clean discussion. If this sounds like something you'd like to participate in, register and become a Dodge Ram Owners Club Member Today! If you have any problems with the registration process or your account login, please contact us.

Ok so ive been searching on here for the best cold air intake and have heard many good things about the Volant. question is is it worth $300 when i can get a Spectre for $125. Another question i havent found answered on here is will they work with a body lift? many of them are ment to just plug and play so will this throw that off by much and if so which brand is mostIncidentally, it's by no means just male students at risk because of the new law. Male professors are at risk, too, as shown by this case, decided under the preponderance of the evidence standard: MSU investigation finds professor sexually harassed student. Let us hope that more professors side with the AAUP in denouncing the new law.

But the most damning condemnation of the new law was posited by a woman who thought she was praising it, found here: "The preponderance standard works well at the University of Tennessee at Chattanooga, says Sara Peters, director of the Women's Center there. Rulings have come down at times in favor of the accuser, and at other times in favor of the accused. 'If you have a judicial board that is trained to


About Courtney

Courtney S. Crooms was born on January 9th 1992 to Derick and Meshal Crooms in Killeen, Texas. Born into a military family, Courtney, along with her older brother Daniel, traveled quite a bit early on, settling in places from Germany to the Washington D.C. area. Always one of the tallest in her class, Courtney became very active in athletics at an early age. She excelled in volleyball, track & field, and her passion… basketball.

As part of a family that stressed the importance of academics and overall well-roundedness, Courtney excelled in the classroom as well, achieving a 3.5 cumulative GPA throughout her entire middle school career, and would have attended the Southwest Atlanta Christian Academy (SACA) as a student, and member of their lady’s basketball team.

Perhaps most importantly,Q:

Pass two or more values without session

How do i send two or more values from a JSP page to another JSP page or servlet without using session? I am new to JSP so suggest something pls?

A:

i can not understand why you will not use session. but you have 4 another way that i know:

use get Parameter:for example you have a link to second jsp file. add your parameter at the end of your link. like this:  mysite.com/second.jsp?param1=value1&param2=value2
use form in the firstjsp page and in this use hidden input:
<form action="second.jsp" method="post">
   <input type="hidden" name="param1" value="value1" />
   <input type="hidden" name="param2" value="value2" />
   <input type="submit" name="next" value="Next Page" />
</form>
use application variable but if your data is general for all, or use


speciall param name for store your value. for example you can use:
<%
    application.setAttribute("user1_param1","value1");
%>
use RequestDispatcher in your code. and set your param in the request object instead of session.
<%
   request.setAttribute("param1","value1");
   RequestDispatcher r=request.getRequestDispatcher("second.jsp");
   r.forward(request, response);
%>

please Subtilize that you can use each other in the different state. for example you can use RequestDispatcher when you will forward a request before send any result ro user. and the other ways use when you will your current data back to you in the second page in the next use request.

groups in its 2016 data. (David McNew/Getty Images)

"It's that minority that is frightening many of us," she said.

"Online hate and these echo chambers of ignorance and anti-immigrant sentiment — these spaces are fuelling a lot of these attitudes," she continued, adding that in her experience, the majority of possible hate crimes — whether perpetrated against Muslims or any other minority group — go unreported.

Difficult to prosecute

In her work with the NCCM, she encountered many people who described the reporting process as uncomfortable and disappointing, leaving victims to wonder whether it is worth the personal cost to do so.

"The police are often not really equipped to address these issues. They're slow to react and they are not providing the necessary support to the victims. We've seen this right across


Let m be 22 + -1 - 1*(-2)/(-2). Suppose -j - 2*j + 35 = -4*s, -j - m = 5*s. Which is the smallest value?  (a) -2/25  (b) f  (c) s
c
Let q be (-684)/(-891) - (-78)/(-143). Which is the second biggest value?  (a) 8  (b) q  (c) -0.4  (d) -14
b
Let n(h) = -h + 0*h - 5 + 12*h + h**2. Let j(o) = 9*o - 2. Let m be j(-1). Let s be n(m). What is the second smallest value in -0.1, s, -1/5?
-1/5
Let o = 0.436 + 4.564. What is the second biggest value in o, -4, -8/5?
-8/5
Let k = -0.105 + -0.705. Let v = k - -0.11. Let d = -3.7 - v. Which is the(-360)/280. Which is the third biggest value?  (a) x  (b) y  (c) 4
b
Let y = -3 + -1. Let l = -1.712 - -1.912. What is the second smallest value in 4, l, y, -2?
-2
Let d = -22804/11 + 2073. Which is the biggest value?  (a) d  (b) -0.4  (c) -31
a
Let g be (10/14 - 1)*1. Let n be (2/(-5))/(-3 - 92/(-30)). Let t be n/(-10) + (3 - (-48)/(-15)). Which is the second smallest value?  (a) t  (b) g  (c) 1/9
c
Let k = -0.0783 + 0.5783. What is the third smallest value in -3, k, -4, 3/4?
k
Let n = 392 - 316. What is the third smallest value in 3, n, -0.5?
n
Let z = 3.9 - -0.1. Let


the BPT should be comparable, as both faculties have conditions that should have a positive effect on motivation and, accordingly, on testing efforts.

Students at Faculty 1 have a choice that is not available at Faculty 2. They can choose which 8 out of 10 BPTs they would like to take. According to the Self-Determination Theory of Ryan & Deci \[[@R16]\], this should increase intrinsic motivation and thus increase the proportion of serious test takers.

In addition, Faculty 1 provides immediate feedback from the computer-based administration. Immediate feedback is important for completing tasks and being satisfied with the work \[[@R17]\], \[[@R18]\], \[[@R19]\]. Therefore, the condition of computer-based administration should also increase the test effort and thus the proportion of serious test takers.

Although the feedback is immediate, there is no dialoguewere planned for each cohort, which the students could choose independently. At both faculties the testing was computer-based. At Faculty 2, additional dates for paper-based testing were offered.

The students at both faculties participated regularly in the BPT. At the beginning of the test, students were informed about the overall study in addition to the regular introduction. The overall study examines the motivation on the BPT and its influence on learning on the BPT. Therefore, the questionnaire contained more questions than the ones given here. In the regular introduction, the participants were asked to complete the questionnaire after the test had been completed and were informed that this participation was voluntary and anonymous. The Ethical Review Board of the Medical Faculty Mannheim, Heidelberg University, approved the study (2015-542-N-MA).

### Analyses

The


responses. At F2, 65/105 (62%) of 105 responses (42% of the 248 responders) were constructive. The allocation of responses to the individual categories per faculty is shown in table 4 [(Tab. 4)](#T4){ref-type="fig"}.

### Perceived benefit at faculties with different examination and feedback conditions

163 (39%) of the students from F1 and 309 (68%) of the students from F2 talk to other people about their BPT results. 84 (20%) of the students from F1 agreed with the statement that they talked with their fellow students about their BPT results. At F2 this number was 147 (32%). The statement that they talked with their mentor about their own results on the BPT was agreed with by 4 (1%) of the F1 students and 16 (4%) of the F2 students. A total ofHello everyone. Stopped by today to ask the opinion of better cooks (and bakers) than myself. Hope to get some good info.

I am making raspberry tartlets and reviewing the recipes, wondering, if I can bake cooked pudding (and if so how long does it need to bake) just right into the shells or if it would be better to make the shells first (so they don't get soggy) and then add the cooked pudding?

Hello everyone. Stopped by today to ask the opinion of better cooks (and bakers) than myself. Hope to get some good info.

I am making raspberry tartlets and reviewing the recipes, wondering, if I can bake cooked pudding (and if so how long does it need to bake) just right into the shells or if it


+ (x) * 0x20)
#define USBA_DMA_BASE(x)	(0x300 + (x) * 0x10)
#define USBA_FIFO_BASE(x)	((x) << 16)

/* Synth parameters */
#define USBA_NR_ENDPOINTS	7

#define EP0_FIFO_SIZE		64
#define EP0_EPT_SIZE		USBA_EPT_SIZE_64
#define EP0_NR_BANKS		1

#define FIFO_IOMEM_ID	0
#define CTRL_IOMEM_ID	1

#define DBG_ERR		0x0001	/* report all error returns */
#define DBG_HW		0x0002	/* debug hardware initialization */
#define DBG_GADGET	0x0004	/* calls to/from gadget driver */
#define DBG_INT		0x0008	/* interrupts */
#define DBG_BUS		0x0010	/* report changes in bus state */
#define DBG_QUEUE	0x0020  /* debug request queue processing */
#define DBG_FIFO	0x0040  /* debug FIFO contents */
#define DBG_DMA		0x0080  /* debug DMA handling */
#define DBG_REQ		0x0100	/* print out queued request length */
#define DBG_ALL		0xffff
#define DBG_NONE	0x0000

#define DEBUG_LEVEL	(DBG_ERR)

#define DBG(level, fmt, ...)					\
	do {							\
		if ((level) & DEBUG_LEVEL)			\
			pr_debug("udc: " fmt, ## __VA_ARGS__);	\
	} while (0)

enum usba_ctrl_state {
	WAIT_FOR_SETUP,
	DATA_STAGE_IN,
	DATA_STAGE_OUT,
	STATUS_STAGE_IN,
	STATUS_STAGE_OUT,
	STATUS_STAGE_ADDR,
	STATUS_STAGE_TEST,
};
/*
  EP_STATE_IDLE,
  EP_STATE_SETUP,
  EP_STATE_IN_DATA,
  EP_STATE_OUT_DATA,
  EP_STATE_SET_ADDR_STATUS,
  EP_STATE_RX_STATUS,
  EP_STATE_TX_STATUS,
  EP_STATE_HALT,
*/

struct usba_dma_desc {
	dma_addr_t next;
	dma_addr_t addr;
	u32 ctrl;
};

struct usba_ep {
	int					state;
	void __iomem				*ep_regs;
	void __iomem				*dma_regs;
	void __iomem				*fifo;
	struct usb_ep				ep;
	struct usba_udc				*udc;

	struct list_head			queue;

	u16					fifo_size;
	u8					nr_banks;
	u8					index;
	unsigned int				can_dma:1;
	unsigned int				can_isoc:1;
	unsigned int				is_isoc:1;
	unsigned int				is_in:1;

#ifdefCONFIG_USB_GADGET_DEBUG_FS
	u32					last_dma_status;
	struct dentry				*debugfs_dir;
	struct dentry				*debugfs_queue;
	struct dentry				*debugfs_dma_status;
	struct dentry				*debugfs_state;
#endif
};

struct usba_request {
	struct usb_request			req;
	struct list_head			queue;

	u32					ctrl;

	unsigned int				submitted:1;
	unsigned int				last_transaction:1;
	unsigned int				using_dma:1;
	unsigned int				mapped:1;
};

struct usba_udc {
	/* Protect hw registers from concurrent modifications */
	spinlock_t lock;

	void __iomem *regs;
	void __iomem *fifo;

	struct usb_gadget gadget;
	struct usb_gadget_driver *driver;
	struct platform_device *pdev;
	int irq;
	int vbus_pin;
	int vbus_pin_inverted;
	int num_ep;
	struct clk *pclk;
	struct clk *hclk;
	struct usba_ep *usba_ep;

	u16 devstatus;

	u16 test_mode;
	int vbus_prev;

#ifdef CONFIG_USB_GADGET_DEBUG_FS
	struct dentry *debugfs_root;
	struct dentry *debugfs_regs;
#endif
};

static inline struct usba_ep *to_usba_ep(struct usb_ep *ep)
{
	return container_of(ep, struct usba_ep, ep);
}

static inline struct usba_request *to_usba_req(struct usb_request *req)
{
	return container_of(req, struct usba_request, req);
}

static inline struct usba_udc *to_usba_udc(struct usb_gadget *gadget)
{
	return container_of(gadget, struct usba_udc, gadget);
}

#define ep_is_control(ep)	((ep)->index == 0)
#define ep_is_idle(ep)		((ep)->state == EP_STATE_IDLE)

#endif /* __LINUX_USB_GADGET_USBA_UDC_H */


verdict, an appellate court must view the evidence and all inferences of fact in the light most favorable to the nonmoving party and can affirm a directed verdict only where no proper view of the evidence could sustain a verdict in favor of the nonmoving party. See Owens v. Publix Supermarkets, Inc., 802 So.2d 315, 329 (Fla.2001); McQueen v. Jersani, 909 So.2d 491, 492-93 (Fla. 5th DCA 2005).
Section 440.205 of the Florida Statutes provides that no employer shall discharge, threaten to discharge, intimidate, or coerce any employee by reason of such employee's valid claim for compensation or attempt to claim compensation under the workers' compensation law. Ms. Andrews' complaint alleged that she was discharged because of her attempt to claim benefits under the workers' compensation law.
In order toa fall at DME caused by a broken curb in the vicinity of DME's outside break area. She subsequently filed a petition for workers' compensation benefits. She was terminated from her employment approximately seven weeks later, after a number of incidents which she contended were retaliation for filing her claim for benefits. Among the events complained of were reprimands for taking breaks that were longer than allowed (which she contended resulted from her taking prescription medication which required her to drink excessive amounts of liquids thus requiring increased restroom usage), and for refusing to sign the warning notice given to her for that incident. In addition, despite outstanding performance scores, she was overlooked for promotions that were given to newer employees. She was terminated after being advised that


Monster House and The Chronicles of Narnia: Voyage of the Dawn Treader.

There are other sections, including music videos, game clips (all PS3-related, naturally), nature clips – all limited to a maximum of five shorts. Ignore the ‘Sony original’ and ‘personal imaging’ section, both of which are merely compilations of adverts, although the entire 3D Experience app is one big ‘look what we can also sell you’ exercise.

It’s elsewhere that the platform shines, with the BBC iPlayer and –uniquely– Demand 5 making-up an enviable catch-up TV service for Brits. Subscribers to Lovefilm will love the chance to stream films, while non-Lovefilmers can rent from Acetrax.

Picture and sound quality

More immediate, strictly 2D digital media can be had from a PC via DLNA streaming, though oddly there’s a lot more flexibilityKarate long served the defensive needs of the indigenous population, post annexation this combative method migrated north and evolved into something new.

In its new form the art would be used to inspire and prepare young men to carry out their duty for Emperor and Empire within the Japanese War Machine. During its transmission a number of notable masters and personalities migrated from Okinawa to Japan, particularly to Osaka and Tokyo to teach the willing student body.

Men such as Funakoshi Gichen, Mubuni Kenwa, Miyagi Chojun and Uechi Kanbun all made their impact which is still celebrated today as notable branches of the Karate family. However one man in particular holds pride of place for “practical” minded Karate-ka, a man who in his own way collaborated in the forming of


his rank within Okinawan society seems not to have felt the full brunt of the law for his actions. Indeed one story recounts that Motobu apprehended an escaped prisoner using his fighting ability.

Moving to Japan later in his life Motobu opened up a dojo in Osaka and began to take on many students. Being part of that generation of masters who transported the Ryukyuan art to mainland Japan, Motobu found that his methods often attracted students of his contemporises which created great riverarly. In particular Motobu and Gichen Funakoshi had a heated riveraly, this situation between the politically shrewd Funakoshi and the blunt Motobu, might explain many of the negative myths surrounding this master as Funakoshi supports looked to discredit him.

Though during his time Motobu took part inWhile there is a substantial amount of modelling activity occurring in South Africa \[[@CR13], [@CR14], [@CR26]\], none of these are run directly by locally-trained National or provincial TB Programme members. This case study shows that, through local ownership, we can better influence decision making, for example through additional funding for TB in 2017--2019 as part of a combined TB/HIV conditional grant.Fig. 4Model outputs for tuberculosis (TB) incidence and mortality in South Africa. The calibration focussed on matching 2012 data and aimed to fit within the confidence intervals around the Global TB Programme (GTB) estimates (thin solid lines). **a** TB Incidence: Modelled incidence (thick solid line) closely matches GTB estimates (dotted line). Model matches disaggregation by HIV status and annual decline in incidence in 2012. **b** Mortality: Modelled mortality


Model. The discussions were continued through repeated visits to establish a long-term collaboration with the NTP and provide continued support along the New Funding Model process (Fig. [5](#Fig5){ref-type="fig"}).Fig. 5Global Fund to Fight AIDS, Tuberculosis and Malaria New Funding Model and country engagement timeline. TRP, Technical review panel; GAC, Grant approval committee. Figure adapted from the Global Fund to show visits to Ghana along the New Funding Model

The TIME modelling framework was used to provide a clear understanding of the current and future epidemic, given the new prevalence survey results and in the absence of further action (Fig. [6](#Fig6){ref-type="fig"}). This showed that, in the absence of additional NTP activities, the prevalence of TB remains stable and may even increase in future years.Fig. 6Model outputs for notifications and prevalence in Ghana. **a**interests this will become weekly or biweekly if there is growing interests this will become weekly or biweekly Posted by

ProjectPT_

on on Quote this Post

" ProjectPT " Monstacookie

Can't make it Tonight but if you plan on organising More of these on a Weekly basis I'd be happy to join! Timer says wed the 12th, right?Can't make it Tonight but if you plan on organising More of these on a Weekly basis I'd be happy to join!

if there is growing interests this will become weekly or biweekly if there is growing interests this will become weekly or biweekly

If you could hold these on weekends, I'd be happy to make a LLD char and participate in most/all of them. If you could hold these on weekends, I'd be happy to make


   A089 097 441
                           UNITED STATES COURT OF APPEALS
                               FOR THE SECOND CIRCUIT

                                 SUMMARY ORDER
RULINGS BY SUMMARY ORDER DO NOT HAVE PRECEDENTIAL EFFECT. CITATION TO A SUMMARY ORDER FILED
ON OR AFTER JANUARY 1, 2007, IS PERMITTED AND IS       The agency also reasonably relied on an inconsistency

8    regarding Zheng’s location when authorities confronted his

9    family about their failure to cooperate with the confiscation

10   of their land.      He repeatedly testified that he was not inside

11   his   home   when    the   authorities   entered;    that      testimony

12   conflicted   with    his   asylum   application    and   his    father’s

13   affidavit, both of which stated that he was having breakfast

14   inside his home


serious case review like the Victoria Climbié case, involving a child with no recourse to public funds, happens,” she says. “We are just waiting for a tragedy to happen.”

A Home Office spokesperson said: “We welcome those who wish to make a life in the UK with their family, work hard and make a contribution. But family life must not be established here at the taxpayer’s expense.

“We work closely with local authorities to ensure that immigration decisions in cases receiving local authority support are made as quickly as possible.

“In exceptional circumstances, or where people granted leave on family grounds show that they would otherwise be destitute, they are granted recourse to public funds.”

Case studies: Christiana

Christiana* was only 18 when she came to London from Sierra Leone, with the promiseappropriate choice of the parameter $M_2$, in order to prove the convergence of an inertial forward-backward algorithm for solving the problem in case $f$ is a convex function.

The following corollary is a direct consequence of Theorem \[th-H\].

\[cor-f+h\] In the setting of Problem 1, suppose that the function $f+h$ is coercive and semi-algebraic, consider the sequences generated in Algorithm 1, where $\nu,\mu,{\underline}\lambda,{\overline}\lambda$ and $\alpha$ are chosen as in Lemma \[m1>m2\]. Then the following statements are true:

-   $\sum_{n\geq 1}\|x_n-p_n\|<+\infty$ and $\sum_{n\in{\mathbb{N}}}\|x_{n+1}-x_n\|<+\infty$;

-   there exists $x\in\operatorname*{crit}(f+h)$ such that $\lim_{n\rightarrow+\infty}x_n=\lim_{n\rightarrow+\infty}p_n=x$.

The function $(x,y) \mapsto M_2\|x-y\|^2$ is semi-algebraic, where $M_2$ is considered as in Lemma \[lemma5\]. Since the class of semi-algebraic functions is stable under finite sums (see [@b-sab-teb]), it follows that $H:{\mathbb{R}}^m\times{\mathbb{R}}^m\rightarrow \operatorname*{\overline{{\mathbb{R}}}}, \ H(x,y)=(f+h)(x)+M_2\|x-y\|^2$ is semi-algebraic as well. The


1. Introduction {#sec1-sensors-20-04037}
===============

Human senses are physiological responses and play a vital role in perception. Humans perceive their surrounding environment using multiple senses, i.e., vision, auditory, gustatory, olfactory, and tactile (touch). The sensing organs transmit information to the human brain, which helps in perceiving the surrounding environment. Traditional multimedia engages only two human senses, i.e., auditory and vision. Whereas the human experience of viewing multimedia content can be enhanced by engaging more than two human senses simultaneously. The multimedia content that can engage more than two human senses simultaneously is termed as multiple sensorial media (mulsemedia) \[[@B1-sensors-20-04037],[@B2-sensors-20-04037]\]. There is a recent focus on mulsemedia with the aim towards providing an immersive real-world environment during multimedia interactions. Mulsemedia could provide a new dimension towards developing immersive systems in diverse fieldsin the following subsections.

3.1. TEM Content Generation {#sec3dot1-sensors-20-04037}
---------------------------

TEM was generated for simultaneously engaging three (vision, tactile, and auditory) human senses. Four different video clips were selected, which were then synchronized with a heater and an electric fan. The first clip was selected from the movie *'Tangled'*, where a character faces opposing effect of air while running on snow. For TEM clip 1 generation, the timestamp (to start the airflow) was identified and synchronized with an electric fan. The second clip was selected from an online source ([youtube.com](youtube.com)), where a character is seated behind an airplane with the opposing effect of air. The timestamp was identified and synchronized with a fan to generate TEM clip 2. The third clip was selected from the movie '*The Lord of the Rings*',


only EEG based features were used which is higher than \[[@B35-sensors-20-04037]\] and lower (by $1.19\%$) than \[[@B36-sensors-20-04037]\]. We argue that this slight decrease in the accuracy is due to an increase in the number of clips. Our proposed emotion recognition system employed a multimodal fusion strategy and achieved a higher accuracy ($79.76\%$) when compared with recently reported methods. Further, the benefit of using TEM content was evident when the classification accuracy for same emotions was evaluated while using videos (without tactile effect) as stimuli. It was observed that the accuracy improved by $\approx 10\%$ when TEM was used for similar video clips. Although improvement in emotion recognition accuracy is achieved but there are certain aspects that need to be further explored in the future. In this study, electric$79.98\%$
  \[[@B78-sensors-20-04037]\]   Videos             Vision, Auditory    ECG, skin temperature, EDA   Negative emotion                 $92.5\%$
  \[[@B53-sensors-20-04037]\]   Videos             Vision, Auditory    ECG, EMG, GSR, PPG           Pleasure, fear, sadness, anger   $93.42\%$
  \[[@B86-sensors-20-04037]\]   Videos             Vision, Auditory    ECG, skin temperature, EDA   Happiness, surprise, anger,      $89\%$


Q:

Calculating C and Gama for LIBSVM

I am calculating values for C and gama for libsvm. Size of my training data is Mat(28539,96); But this search is taking a long time. My laptop is On since last two days and still search is in progress. How to solve this issue, anybody has any idea. Help will be appreciated

A:

if you are using grid.py - inside you find the parameters
telnet_workers = []
ssh_workers = []
nr_local_worker = 1

where you can configure external helpers and the number of local threads. try to increase the number of local threads until your machine is (near) 100% loaded.

out with someone. He really liked me and I liked him. We have some common interests and well, it's pretty obvious after that. So I decide to tell my dad. He doesn't say anything and lets it go. I assume the year has really changed, and their minds have changed also. Terror comes when I tell my mom.

She had the same high tempered attitude as the year before. This time though, it looked like 10x worse. It was as if I had done something that's crucially wrong. My dad was in the room, but he couldn't say anything yet.

The moment though, I explode back was when she mentioned the "bandwagon" again. That sparked me and all three of us had a long argument. In her eyes, all I


with the key attached, I would rotate it and break the key off permanently!!!"

This exact phrase took me down.

My parents wanted me to break up with my bf. And so I did the next day. I did with saying some really bad things I regret saying. It was a force that came upon me since I could take hold of myself from the argument. Because of that, he never talked to me again.

This guilt (that I supposedly "need" to feel) is weighed down by them. Me being bisexual is the worst possible damage their son can do to the world. And what for? He's taking control and has his own life.

Then at school, I'm a completely different person. They all know me, know who I like, and itQ:

Fading a shadow together with the SKSpriteNode that casts it

Here's my setup, using Sprite Kit. First, I create a simple sprite node within a SKScene, like so:
let block = SKSpriteNode(color: UIColor.redColor(), size: CGSizeMake(90, 160))
block.zPosition = 2
block.shadowCastBitMask = 1
addChild(block)

Then add a light node to the scene:
let light = SKLightNode()
light.categoryBitMask = 1
light.falloff = 1
addChild(light)

Sure enough, the block now casts a nice little shadow:

Now I fade the block by manipulating its alpha value, for example by running an action:
let fadeOut = SKAction.fadeAlphaTo(0.0, duration: 5.0)
block.runAction(fadeOut)

Here's the awkward situation: while the block becomes more and more translucent, the shadow stays exactly the same. This is how it looks like just a moment before the end of the action:

And once the alpha drops to 0.0 entirely, the shadow suddenly disappears, from one frame to


We will call $\phi (p_{i})$ the *sign* of $p_{i}$, and the function $\phi$ could be thought of as an orientation of $\{p_1,\ldots,p_n\}$. If $\phi$ is the constant function equal to $+1$ (resp. $-1$), we set $P^{\phi}_n=P_n^+$ (resp. $P^{\phi}_n=P_n^-$).

Given two objects $P_{n}^{\phi }$ and $P_{m}^{\psi }$, a morphism from $P_{n}^{\phi }$ to $P_{m}^{\psi }$ is an oriented $(n,m)$-tangle, that is an oriented $1$-submanifold $\tau$ of $D \times I$, whose oriented boundary $\partial\tau$ equals $$\begin{aligned}
\sum_{i=1}^{m}\psi(p_i)(p_i,1) - \sum_{i=1}^{n}\phi(p_i)(p_i,0)\;,\end{aligned}$$ considered up to ambient isotopy of the cylinder that keeps $D\times \partial I$ fixed. Note that a morphism from $P_{n}^{\phi }$ to $P_{m}^{\psi }$ exists if only if $\sum_{i=1}^{m}\psi(p_i)=\sum_{i=1}^{n}\phi(p_i)$. A morphism from $P_{n}^{\phi }$ to $P_{m}^{\psi }$ will be called a $(\phi,\psi)$-tangle or sometimes just an $(n,m)$-tangle when we don’t need to referwith $\partial^-\tau_2$, and rescaling the resulting solid cylinder to $D\times I$.

$\lambda _{k}^{\phi}$ at 98 100 $-(p_1,1)$ at 35 365 $(p_{2},1)$ at 135 365 $-(p_{k},1)$ at 388 365 $(p_{k+1},1)$ at 670 365 $-(p_{2k-1},1)$ at 905 365 $(p_{2k},1)$ at 1030 365 $\chi_1$ at 540 -10 $\chi_2$ at 540 45 $\chi_k$ at 540 190

![The cup tangle $\lambda_k^{\phi}$ of type $\phi$.[]{data-label="fig_cupcap1"}](CupCap1a)

Given an object $P_n^{\phi}$, we denote by $P_n^{-\phi}$ the object obtained by changing the signs of all the points. If $\tau$ is a morphism from $P_{n}^{\phi }$ to $P_{m}^{\psi }$, then $-\tau$ is a morphism from $P_{n}^{-\phi }$ to $P_{m}^{-\psi }$, where $-\tau$ is obtained from $\tau$ by changing the orientation of each component. Moreover, we denote by $\overline{\tau }$ the image of $\tau$ under the homeomorphism $D\times I \to D\times I$,


330 $-(p_1,0)$ at 70 30 $(p_{2},0)$ at 175 30 $-(p_{1},1)$ at 70 480 $(p_{k},0)$ at 445 30 $(p_2,1)$ at 175 480 $(p_k,1)$ at 445 480 $\chi_1$ at 65 220 $\chi_2$ at 155 220 $\chi_k$ at 425 220 $\chi_1$ at 680 250 $\chi_2$ at 845 250 $\chi_k$ at 1195 250

![The trivial tangle $T_k^{\phi}$ and the plat tangle $\mu_k^{\phi}$ of type $\phi$.[]{data-label="fig_cupcap2"}](CupCap2)

The tangle category is a strict monoidal category, which means it has a tensor-like product. The tensor product of two objects $ P^{\phi}_n\otimes P^{\psi}_m$ (resp. two tangles $\tau_1\otimes\tau_2$) is the sequence of $n+m$ points (resp. tangle), obtained by juxtaposing $P_m$ (resp. $\tau_2$) to the right of $ P_n$ (resp. $\tau_1$), keeping the signs. This operation is associative and has the empty sequence as the (left and right) identity object.\
Byforgetting signs and orientation, we obtain a surjective faithful forgetful functor from $\mathcal T^+$ to $\mathcal T$, where $\mathcal T$ is the *tangle category*, that is the category whose objects are (possibly empty) finite ordered sequences of points and whose morphisms are tangles. We denote by $P_n$ the image of $P_n^{\phi}$ in $\mathcal T$, while the image of an oriented tangle $\tau$ will still be denoted by $\tau$.

\[rem\_closing\] In the tangle category, a link in $\mathbb R^3$ or $S^3$ can be seen as a morphism from the empty set to itself, while braids on $k$ strands are isomorphisms of $P_k$. With this in mind, we can rephrase and extend the notions of classical closure and plat closure of braids to tangles as follows. Given a $(k,k)$-tangle $\tau$, the


fundamental quandle of $P(3,3,3)$ has a presentation $$\begin{aligned}
  \langle y_{i,z}\mid &\
  y_{3,z}{\triangleright}y_{4,z}=y_{1,z}, y_{4,z}{\triangleright}y_{3,z}=y_{2,z}, y_{5,z}{\triangleright}y_{2,z}=y_{3,z},  y_{4,z}=y_{1,z+1},\\ &\ y_{5,z}=y_{2,z+1}, z=1,2,3, \ i=1,\ldots ,5\rangle,
 \end{aligned}$$ that simplifies to $$\langle y_{1,z},y_{2,z}\mid (y_{2,z+1}{\triangleright}y_{2,z}){\triangleright}y_{1,z+1}=y_{1,z}, \ y_{1,z+1}{\triangleright}(y_{2,z+1}{\triangleright}y_{2,z})=y_{2,z}, z=1,2,3\rangle,$$ where all the second indices are counted mod $3$.

[Composite knots]{} \[appl2\]

Let $K_1$ and $K_2$ be two nontrivial knots in the solid cylinder $D\times I$. Choose decompositions $K_1=\widehat{\tau_1}$ and $K_2=\widehat{\tau_2}$, where $\tau_1,\tau_2$ are $(1,1)$-tangles. The connected sum $K_1\sharp K_2$ of $K_1$ and $K_2$ can be expressed as $\lambda_1\left(\tau_1\otimes\tau _2\right)\overline{\lambda}_1$. While tangles $\tau _1$ and $\tau _2$ clearly depend on the chosen decomposition, the connected sum $K_{1}\sharp K_2$ is uniquely defined by $K_1$ and $K_2$.

$\overline{\lambda }_{1}$ at 420 -30 $\tau _1$ at 130 310 $\tau _2$ at 700 310 $\lambda _1$ at 420 560 $x_1$ Q(K_1\sharp K_2)=\langle& x_1,\ldots,x_k, y_1\ldots, y_n,X,Y\mid r_1,\ldots,r_h, s_1,\ldots, s_m,  x_1=y_1, X=Y\rangle.
  \end{aligned}$$

$x_1$ at 40 140 $x_2$ at -5 20 $x_3$ at -10 160 $X$ at 100 20 $Y$ at 230 20 $y_1$ at 290 140 $y_3$ at 335 160 $y_2$ at 335 20

![The granny knot.[]{data-label="fig:granny"}](Granny)

\[ex2\] Consider the knot depicted in Figure \[fig:granny\]: its name is the granny knot and it is obtained as a connected sum of the left-handed trefoil knot $3_1$ with its mirror image $3_1^*$ (the so called right-handed trefoil knot). Using the left (respectively right) part of the diagram in Figure \[fig:granny\], we obtain the following presentations

[1]{} & Q(3\_1)=x\_1,x\_2,x\_3,X | x\_3 x\_1 =x\_2, x\_2 x\_3 = x\_1, Xx\_2 = x\_3, x\_1 = X,\
& Q(3\_1\^\*)=y\_1,y\_2,y\_3,Y | y\_3 y\_1 =y\_2, Y y\_2 = y\_3, y\_2


diagram $D_{\tau}$ in $[-1,1]\times I$. Denote by $x_1,\ldots, x_r$ the arcs (or curves) of $D_{\tau}$ and by $C_1,\ldots, C_s$ its crossings. Fix $\vec{\epsilon}\in \{-1,1\}^N$, and let $\vec{\epsilon}\tau$ be the $N$-cable of $\tau$, oriented so that the $j$-th copy of $\tau$ has the same orientation as $\tau$ if $\epsilon_j=+1$ and the opposite one otherwise. Then we have: $$Q(\vec{\epsilon}\tau)=\langle \{x_{ij},\ i=1,\ldots, r, \ j=1,\ldots, N\} \mid \{r_{kj},\  k=1,\ldots, s,\  j=1,\ldots, N\}\rangle,$$ where $r_{kj}: x_{ij}= \left(\cdots\left(\left( x_{hj}\rhd^{\epsilon_1} x_{l1}\right) \vartriangleright^{\epsilon_2} x_{l2}\right)\vartriangleright^{\epsilon_{3}}\cdots \vartriangleright^{\epsilon_{N-1}} x_{l(N-1)}\right) \vartriangleright^{\epsilon_N} x_{lN}$ if the arcs of the crossing $C_k$ are labeled as depicted in the left part of Figure \[fig\_ntangle\], and where $\vartriangleright^{1}=\vartriangleright$, $\vartriangleright^{-1}=\vartriangleleft$.

$x_{i}$ at 0 320 $x_{l}$ at 300 320 $x_{h}$ at 300 620 $x_{i_{1}}$ at 700 -20 $x_{i_2}$ at 640 40 $x_{i_N}$ at 530 160to the DLOTI frequency and institution. This result is considered to not be mainly caused by specific disinfection instructions. In other words, it is possible to have a qualitative difference according to each person in charge of disinfecting the laryngoscope by the guideline, such as just wiping it with a disinfection wipe. Structural problems such as the grid-type knurled surface cause contamination \[[@b12-jpmph-50-3-158],[@b13-jpmph-50-3-158]\], but differences according to the intubation frequency and medical institution will be regarded as crucial reason for contamination; thus, the reinforcement and standardization of disinfection instructions are required. Additionally, unclear regulations for maintenance are another cause of bacterial contamination that require improvement.

*Bacillus* spp., coagulase-negative staphylococci, *Acinetobacter* spp., *Micrococcus* spp., and *Corynebacterium* spp., the highest isolated strain (67.2%), can spread through the air \[[@b22-jpmph-50-3-158]\]. To prevent


paid for time that they did not work, nor have I requested anyone to be paid in such a way," he insisted, calling the lawsuit "frivolous, false and without merit."

But a federal judge concluded: "Plaintiff's allegations suggest corruption in the expenditure of public funds."

The judge added, "There is no suggestion that other candidates were evaluated for the position of Defendant's assistant's assistant. Nor is there any indication that the creation of such a position was warranted."

After the federal judge refused to dismiss the lawsuit, NewsChannel 5 discovered, Gobble's county lawyer settled the case -- under terms that, Gobble said, are secret, although he still insisted that he did nothing wrong.

Still, the TBI nominee denied that it was a mistake in judgment for him to have hired his wife.

Histrouble." " You'll report me?" " No." "I'm only warning you." "You don't know how things are." " These little games can cost you." " Let me go." "Believe me." "Julia." "Please." "What do you want to do?" "See a movie?" "Sorry, wrong apartment." "I'm looking for Juana." " Who are you?" " Her nephew." "It's the next floor." "Sorry." " Anybody see you?" " No." " You're crazy to come here." " Who was that officer?" "They're everywhere." "They've come for the parade." " Staying wherever they can." " And my folks?" "The police took them." "The neighbor reported them." "You have to leave." "And don't come back." "If you do, I'll call the police myself." "That way!" "That way!" "He went that way!" "Sir." "How are


the fatherland." "Coming!" " Sir." " At ease." "And open the door." " Stop, somebody could see us." " At this hour?" "Yes." "My mother must be worried." "Stop." "You have to go." "Go." "Go." "Carmen." "Who is that soldier?" "What are you doing here?" "Who is he?" "He's not a soldier." "He's my boyfriend." "Is that why you stopped coming?" "We thought something had happened to you." "I lost my job." "You know my situation at home." "Getting arrested would be a disaster." "Don't take this wrong... but you should give it up too, kid." "All that risk and sacrifice." "Will anything come of it?" "Don't call me "kid. "" "We're full, there are no rooms." "Is Valentin there?" "Come in, Teo." "What happened to you?" "Theconversations." " Did he mention the parade?" " Like I said, we weren't always listening." "But it's likely." "Did he have visitors?" "Not very many." "The other day." "You." "A lady came the other day." "The wife of a musician he played with." "What did they talk about?" "Have you ever heard him mention guns?" "Or explosives?" "And to that woman, did he mention guns?" "Yes." "She brought him a lot of money." "I hope our information is correct." "Go take a stroll." "Mario, let's go." "What do you want?" "We're full." "Is Valentin there?" "I'm his girlfriend." "Come in." "Thank you." "Our friends in prison need our help." "But we need money." "We have to do something." "Rob a store, a tobacconist's..." "An easy job." "I've already


let us see her." "What if they don't let you out after?" "Go on." "Mother." "Adelina." "Good morning." "Arrua!" "You promised you only had a few questions for her." "We're only going to question her." "Take her away." "Chief, remember we had a deal." "I promised to bring her and you gave me your word you'd leave her alone." "Your duty was to bring her." "You've done your duty." "Congratulations." "Now please go away." "They're swatting us like flies." "What do we do, Teo?" "What happened?" "They picked up Julia at her house." "It's like they know everything about us." "Like someone's telling them..." "We have to stick together." "What about the others?" "What about Satur and Damian?" "Who?" "Satur and Damian." "Do you know how to findafraid of me." "I don't bite." "I'm not afraid of you." "Hello, Father." "It's good to see you." "How are you?" "Fine." "How are you, darling?" "I'm doing just fine." "I brought you... some clothes." "I thought..." "I don't know." "Tell me what you need." "Mother is very upset." "Seeing you in here wouldn't have helped." "The doctor told her to rest." "To rest!" "But you know her." "She's asking neighbors for signatures saying you were never political." "Will any of them sign?" "Sure." "How could they?" "You've been concierges for years without any complaints." "It's because of me, right?" "They would never employ the parents of a Red." "How is Carmen?" "Fine." "They arrested her father." " And her mother..." " What?" "Her mother went into hiding."


to pardon us, kid." "I can't stop thinking about my mother." "Poor thing." "This must be so hard for her." "Midnight." "We can rest at ease now." "They won't come for us tonight." "Really?" "Sleep easy." "Let's go!" "Get back!" "Move over!" "Let's go!" "Move it!" "Move it!" "My God, it can't be..." "Blanca Brisac Vazquez." "You have to look pretty." "You're going to see Valentin." "Come on, hurry up!" "You're in such a hurry to kill us?" "Martina." "Victoria." "Carmen..." "Go on, wash up." "This can't be happening." "Franco hasn't answered yet." "You're thirsty for blood!" "Murderers!" "Get moving!" "Where's Victoria?" "Tell my mother I'm innocent." "Please." "There!" "I don't want to die, ma'am!" "Let's go!" "If you don't confess, you can't send a letter." "It's up      return {something: 'hi'};
      },
      onMouseEnter: ReactDoNotBindDeprecated.doNotBind(mouseDidEnter),
      onMouseLeave: ReactDoNotBindDeprecated.doNotBind(mouseDidLeave),
      onClick: mouseDidClick,

      // auto binding only occurs on top level functions in class defs.
      badIdeas: {
        badBind: function() {
          this.state.something;
        }
      },

      render: function() {
        return (
          <div


 handleClick: function() { },
      render: function() {
        return <div onClick={this.handleClick.bind(this)} />;
      }
    });

    ReactTestUtils.renderIntoDocument(<TestBindComponent />)

    expect(console.warn.argsForCall.length).toBe(1);
    expect(console.warn.argsForCall[0][0]).toBe(
      'Warning: bind(): You are binding a component method to the component. ' +
      'React does this for you automatically in a high-performance ' +
      'way, so you can safely remove this call. See TestBindComponent'
    );
  });

  it('does not warn if you pass an auto-bound method to setState', function() {
    spyOn(console, 'warn');

    var TestBindComponent = React.createClass({
be examined for even highly decayed remnants.

Additional data files
=====================

The following additional data are available online with this paper. Additional data file [1](#S1){ref-type="supplementary-material"} contains Materials and methods for the analyses performed. Additional data file [2](#S2){ref-type="supplementary-material"} describes in detail the comparison of different BLAST-based criteria for presence/absence detection. Additional data file [3](#S3){ref-type="supplementary-material"} is a table listing the composition of the analyzed genome groups.

Supplementary Material
======================

###### Additional data file 1

Materials and methods.

######

Click here for file

###### Additional data file 2

Comparison of different BLAST criteria to detect gene presence/absence.

######

Click here for file

###### Additional data file 3

Thirty-two groups of genomes with ANI = 94% within each group.

######

Click here for file

Acknowledgements
================

This work was supported through CIHR (MOP-4467) and Genome Atlantic (Genome Canada) grants to W.F.D. O.Z. is supported through a CIHR Postdoctoral Fellowship


Justin Bieber Takes to Twitter to Clear Up Whether He Peed His $690 Sweatpants

Justin Bieber went out in $690 Vetements sweatpants Wednesday and appeared to have had a bit of an accident. At first he was chill about it and even posted a meme on his newly revived Instagram yesterday afternoon:

Instagram

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Then a couple of hours passed, and it appears he realized his fans might not get the gag. What if people really believed he—

So Bieber took to Twitter to explain to the world it really is not that; some water just spilled on what he charmingly describes as his "dick area."

Twitter

It's also okay if you thought that initially, he adds. "Didn't bother me if it made ya laugh nice!" Not at all, because heexpression constructs DAPk/ΔCaM and DAPk-DD (comprising just the death domain residues), suggesting that the over-expressed DAPk-DD can act in a dominant negative fashion perhaps by sequestering factors required for endogenous DAPk activity [@pone.0070095-Cohen2].

The death fold superfamily of proteins includes the following four families: death domains (DDs), death effector domains (DEDs), caspase recruitment domains (CARDs) and PYRIN domains (PYDs). Whilst these protein families can be distinguished on the basis of pairwise sequence similarities, structure determination of representative members of each family has revealed that they share a common architecture consisting of six amphipathic α-helices (H1−H6) arranged in a compact, mostly antiparallel topology in which the N- and C-terminii are close together. Within each of the death fold families, the buried residues of H2 through H5 exhibit relatively high sequence


the accompanying colorimetric detection protocol were used for the Western blots. Incubation with the His-tag antibody was for 1 h and the blocking solution contained 5% milk. Seeblue2 protein markers (Invitrogen) were used for SDS-PAGE separation.

Isothermal Titration Calorimetry {#s2i}
--------------------------------

For isothermal titration calorimetry (ITC) measurements the protein samples were extensively dialyzed against 50 mM HEPES (pH 7.5), 50 mM NaCl, 1 mM TCEP and 1 mM EDTA, and concentrated to the required level. Experiments were performed with a VP-ITC calorimeter (MicroCal): 19 aliquots of 15 µl of 159 µM GB1-DAPk-DD(L), or 250 µM of GB1-DAPk-DD(S), or 100 µM GB1 were injected into 1.45 ml of 8.85−18.6 µM ERK2 (different concentrations of ERK2 were employed for each titration) at 25°C. Experiments were repeated twice. Following subtraction of the corresponding heatssignal for the DAPk-DD at 40% v/v TFE was 57% higher (more negative) at 222 nm (−15,951 deg.cm^2^.dmol^−1^) than in the absence of TFE, but lower when compared with the signal for the FADD-DD (∼−25,000 deg cm^2^ dmol^−1^). The addition of 40% v/v TFE to the GB1-FADD-DD construct gave rise to a modest signal increase of 19% at 222 nm, suggesting that the helical content of this protein is closer to the maximum 'capacity' of the polypeptide sequence than for the DAPk-DD. The 2D ^1^H-^15^N HSQC spectrum of GB1-DAPk-DD(L) did not show any major change in signal dispersion in the presence of 40% v/v TFE ([Figure 4B](#pone-0070095-g004){ref-type="fig"}). There was a slight decrease in resonance line widths and a minor increase in signal dispersion, but without significant perturbation of


acid stretch that is a close match to the F-site consensus. Thus the observed binding of DAPk-DD to ERK2 is likely attributable, at least in part, to an occupation of the DRS by one of the (non-exact) D-motifs that would be available within a disordered form of the DAPk-DD polypeptide. In fact, in the absence of an induced-fit mechanism, a globular DD-fold would, by homology, sequester the critical Φ~A~-X-Φ~B~ hydrophobic residues in the core of the domain. However, neither the N- or C-terminal truncation mutants of DAPk-DD are competent to bind ERK2, therefore suggesting that binding must involve additional contacts outside of the putative DRS/D-motif interaction. This is reminiscent of the conclusions drawn for PEA-15 which is suggested to bind ERK2 in a 'bidentate' fashion [@pone.0070095-Callaway1], [@pone.0070095-Callaway2].

In summarythink that empty Fall 2018 release date is extremely likely. Currently there’s an untitled DC Comics movie dated for October 5, 2018.

Check out Manganiello’s comments for yourself in the video below.

SOURCE: ET


the event of bank failure, the state under EU regs guarantees deposits up to a certain amount. But are there any conditions to this? Must they be saving account deposits or do current account deposits apply too, for example?
Further, which state guarantees the account? The state where the account holder is resident, the state where the bank account is, or the state of the bank account's company, or something else (eg: an EU fund)? (And for extra bonus points, how, if at all, is that affected by Brexit?)

A:

The limit is €100,000, or the equivalent in the local currency.  So it's £85,000 in the UK.  That's guaranteed by the state where the bank is registered to do its business.
The guarantee applies to any personal cash savings accounts,attack. With Miles Morales, Gwen Stacy, and Anya Corazon starting to fight back mentally, Spider-Man works with Lady Octopus to fight Doctor Octopus physically. With the resulting fight placing Doctor Octopus in a coma, Spider-Man admits that Lady Octopus made a terrible supervillain as the police start to arrive at Horizon High. After being told by Spider-Man not to blow her second chance like Doctor Octopus did, Carolyn discards her tentacle harness and takes her leave.

Video games
 Lady Octopus appears in a teaser image for Season Two of Marvel: Avengers Alliance where it parodies the cover of X-Men #141 (the opening issue of the Days of Future Past storyline). In Chapter 9 as part of the fifth mission, Lady Octopus is found dead alongside Armless Tiger Man and


package er.attachment.processors;

import java.io.File;
import java.io.FileInputStream;
import java.io.IOException;
import java.io.InputStream;

import com.webobjects.appserver.WOContext;
import com.webobjects.appserver.WORequest;
import com.webobjects.eocontrol.EOEditingContext;
import com.webobjects.foundation.NSTimestamp;

import er.attachment.model.ERFileAttachment;
import er.extensions.foundation.ERXFileUtilities;
import er.extensions.foundation.ERXProperties;

/**
 * ERFileAttachmentProcessor implements storing attachments as files on the system that are either served
 * via a proxy request handler or directly by the webserver.  For more information about configuring
 * an ERFileAttachmentProcessor, see the top level documentation.
 *
 * @property er.attachment.[configurationName].file.proxy
 * @property er.attachment.file.proxy
 * @property er.attachment.[configurationName].file.overwrite
 * @property er.attachment.file.overwrite
 * @property er.attachment.[configurationName].file.filesystemPath
 * @property er.attachment.file.filesystemPath
 * @property er.attachment.[configurationName].file.webPath
 * @property er.attachment.file.webPath
 *
 * @author mschrag
 */
public class ERFileAttachmentProcessor extends ERAttachmentProcessor<ERFileAttachment> {
  @Override
  public ERFileAttachment _process(EOEditingContext editingContext, File uploadedFile, String recommendedFileName, String mimeType, String configurationName, String ownerID, boolean pendingDelete) throws IOException {
    boolean proxy = true;
    String proxyStr = ERXProperties.stringForKey("er.attachment." + configurationName + ".file.proxy");
Antarctic Peninsula warming: natural variability or “global warming”?

August 23rd, 2012 by eric

Figure 2. Temperature anomalies averaged over the Southern Hemisphere (top), temperatures from the sub-Antarctic station Orcadas (middle), and hydrogen isotopes (a proxy for temperature) from James Ross Island on the Antarctic Peninsula (bottom). All the data are publicly available: GISS, SCAR, Nature

Why the ambiguity? After all, the results show that it’s now warmer on James Ross Island now than it has been at any time during at least the last millennium (see Figure 2), and its unequivocal that this recent warmth led to the demise of ice shelves in the area over the last few decades. Moreover, the rate of recent century-scale warming is at the upper limit of rates in the pre-anthropogenic era: Mulvaney et al.


that
plaintiff was not entitled to injunctive relief. Plaintiff did not demonstrate that she would prevail
on the merits of her claim because she failed to produce any actual evidence of election fraud.
She relied on her affidavit outlining what she observed on Election Day regarding the absentee
ballots. But the processing of absentee ballots was fully explained by the affidavit of Daniel A.
Baxter, the director of the City of Detroit Department of Elections. 2 Consequently, there was no
evidence to show that the photocopy procedure was a violation of the manual, that it had an
effect on the election, or that the election results were based on fraud. Thus, plaintiff did not
demonstrate that she would suffer irreparable harm if the absentee ballots were not enjoined from
inclusion in the election results. Hammel, 297 MichApp at 648. Plaintiff also failed to
demonstrate that she would be harmed more by the absence of an injunction than defendants
would be by the granting of the relief. Id. The trial court noted that enjoining inclusion of all
absentee ballots would have a significant effect on closer races of the general election. Lastly,
there would be great harm to the public interest if the injunction was issued. Id. More than
31,000 voters voted by absentee ballot in the general election, and plaintiff sought to enjoin
inclusion of all absentee ballots. This would lead to the disenfranchisement of nearly one-third
of all the votes cast in that election. In the absence of any proof of election fraud, the injunction
would pose a great harm to the public interest by disenfranchising so many voters.


     Thus, the trial court did not abuse its discretion when it determined that plaintiff was not
entitled to injunctive relief and did not err when it dismissed plaintiff’s claims. Plaintiff also
asserts that dismissal was improper because no discovery had taken place. However, MCR
2.116(I) does not require discovery before a court may grant summary disposition. Instead, the
court rule permits the trial court to grant summary disposition based on the pleadings, affidavits,
or other offers of proof “without delay.” MCR 2.116(I)(1).

        Plaintiff also avers that “[a]lthough the complaint alleged that the actions of city officials
diluted the votes of black Detroiters in violation of laws including the VRA, this matter was not
properly heard.” Plaintiff’s emergency complaint merely alleged that Winfrey “violatedto which
       members of a protected class have been elected to office in the State or political
       subdivision is one circumstance which may be considered: Provided, That nothing
       in this section establishes a right to have members of a protected class elected in
       numbers equal to their proportion in the population.

“The essence of a § 2 claim is that a certain electoral law, practice, or structure interacts with
social and historical conditions to cause an inequality in the opportunities enjoyed by black and
white voters to elect their preferred representatives.” Thornburg v Gingles, 478 US 30, 47; 106
S Ct 2752; 92 L Ed 2d 25 (1986).


    group have been denied access to that process;

       5. the extent to which members of the minority group in the state or political
       subdivision bear the effects of discrimination in such areas as education,
       employment and health, which hinder their ability to participate effectively in the
       political process;

       6. whether political campaigns have been characterized by overt or subtle racial
       appeals;

                           The U.S. military conducted a successful nuclear-capable intercontinental ballistic missile test Wednesday, just days after North Korea conducted its own ICBM test.

The U.S. Air Force launched a Minuteman III from the Air Force’s North Vandenberg Air Force Base just before dawn. The launch follows the successful test of North Korea’s Hwasong-14 ICBM, which experts and intelligence officials assess can strike American cities across the country.

WATCH:

The test was planned in advance and was not a direct response to North Korea’s actions, but it undoubtedly sent a message.

“While not a response to recent North Korean actions, the test demonstrates that the United States’ nuclear enterprise is safe, secure, effective and ready to be able to deter, detect and defend against attacks on the United States and its allies,” the Air


2020, I sent Sanders' Senate spokesperson three questions by email. I then spoke to him on the phone to alert him to the fact that I had sent these questions.

They were:

1: "Does Sen. Sanders' 'Medicare-for-all' bill prohibit discrimination based on religion — just as it prohibits discrimination based on 'gender identity' and 'pregnancy termination'? If so, what is the specific language in the bill (that) prohibits discrimination based on religion?"

2: "Does the bill allow Catholic hospitals that refuse to perform 'termination of pregnancy' procedures (n.b. abortions) to be qualified providers who continue to provide health care under Sen. Sanders's 'Medicare-for-all' program? If so, is there language in the bill that specifically spells out this exception for religious hospitals and what is that language?"

3: "If the bill does notits market position as a full-service provider in the industry. The firm’s focus is on development services and products in micro injection moulding and micro lumen extrusion of thermoplastic and silicone medical devices.

“Demand for medical devices made of plastic and silicone as well the capability to combine and assemble them has been increasing steadily over the last few years, as have the quality requirements that these products have to meet,” says Werner Karau, European commercial leader at Flexan. According to a survey by US market research firm Global View Research, this upward trend is set to continue. By 2025, global sales of silicone medical devices will reach approximately USD 597 million, with an average annual growth rate of 6.6 per cent. In light of this, in order to


an advantage in the manufacture of thin-walled products and also allows for complex geometries, the varying consistencies of the silicones on the market require extremely precise tooling to prevent leaks and burrs. “We’ve been working closely with certified tool and mould makers for many years now, which means we can make the necessary adjustments and modifications quickly and cost-effectively during prototyping. So it takes us very little time to produce a custom injection moulding tool for every job,” says Karau. This flexibility is key, because customer requirements in extrusion are essentially increasing with every new product. Buyers want multi-lumen or multi-chamber hoses with smaller and smaller diameters and thinner walls. “Our task is to develop the right process time and time again, and to identify the right materiala de novo standard "unless the benefit plan gives the administrator or fiduciary discretionary authority to determine eligibility for benefits or to construe the terms of the plan." Firestone Tire and Rubber v. Bruch, 489 U.S. 101, 115, 109 S.Ct. 948, 956, 103 L.Ed.2d 80 (1989); Stock v. SHARE, 18 F.3d 1419, 1422 (8th Cir.1994); Collins v. Central States Health & Welfare Fund, 18 F.3d 556, 559 (8th Cir.1994); Farley v. Benefit Trust Life Ins., 979 F.2d 653 (8th Cir. 1992); Cox v. Mid-America Dairymen, Inc., 965 F.2d 569, 571 (8th Cir.1992); Finley v. Special Agents Mut. Ben. Assn., 957 F.2d 617, 619 (8th Cir.1992); Oldenburger v. Central States, S.E. & S.W. Areas Teamster Pension Fund, 934 F.2d 171, 173 (8th Cir. 1991).
In this case there is no


determination, at the time the determination was made.
The Committee had before it a substantial amount of information regarding the status of plaintiff's disability. In 1990, plaintiff's treating ophthalmologist, Dr. W. Howard Lewin, testified at a deposition that his last exam of plaintiff, in 1988, showed that she had long-standing optic atrophy in her right eye (presumably from a childhood injury or defect) and a very limited visual field in her left eye. Although her pupils reacted to various tests, she reported virtually no vision to Dr. Lewin. He concluded that she was "legally blind" but could not give a definitive opinion as to whether or not she was "malingering" because of the substantiated loss of vision in her right eye. As to Dr. Sanan Saengsamran's medical assessments, theAfter 24 h, cells were harvested at the indicated times (4, 8, 12, and 24 h). Proteins in the RIPA buffer cell lysates (20 μg) were separated by 12% SDS-PAGE and transferred to a polyvinylidene difluoride (PVDF) membrane. The membrane was then blocked with 5% BSA for 1 h and incubated at room temperature for 1 h with primary antibodies (1:1,000 dilution) against anti-IRF3, anti-STAT1, anti-TBK1, anti-phospho-IRF3, anti-phospho-STAT1, and anti-phospho-TBK1 antibodies (Cell Signaling Technology, Boston, MA, USA) and β-actin (Cell Signaling Technology, Boston, MA, USA). After washing the blot in TBS three times, HRP-conjugated secondary antibodies (1:2,000 dilution) were incubated at RT for 1 h. Protein bands were visualized using a chemiluminescent reagent (Thermo Scientific, Waltham, MA, USA), and the relative intensities of protein bands were measured using


Image J.

Identification of phytochemical constituents
--------------------------------------------

Fifteen authentic standards were used for the identification of phytochemicals in WEF. Psoralen (1), angelicin (2), rutin (3), quercitrin (4), isoquercitirin (5), syringin (9), caffeic acid (10), 1,3-dicaffeoylquinic acid (11), sweroside (15), and scopoletin (internal standard) were purchased from ChemFace (Wuhan, China). Quercetin (6), neochlorogenic acid (7), chlorogenic acid (8), *p*-coumaric acid (12), ferulic acid (13), and *o*-coumaric acid (14) were obtained from Sigma-Aldrich Co. (St. Louis, MO, USA). The analyses were performed using a Dionex UltiMate 3000 system (Dionex Corp., Sunnyvale, CA, USA) equipped with Thermo Q-Exactive (Thermo Fisher Scientific, Bremen, Germany). The separation was carried out on an Acclaim RSLC 120 C18 column (150 × 2.1 mm, 2.2 μm, Dionex Corp.). The mobile phase comprised acetonitrile (A) and 0.1% formic acid inwater (B, v/v). Gradient elution was carried out as follows: 5% A, 0.0--1.0 min; 5.0--15.0% A, 1.0--5.0 min; 15.0--30.0% A, 5.0--12.0 min; 30--50% A, 12.0--15.0 min; 50--65% A, 15.0--17.0 min; 5--5% A, 17.0--22.0 min. The flow rate was 0.25 mL/min. The operation conditions in the MS/MS analysis were set as follows: ionization mode, positive; spray voltage, 4.0 kV; capillary temperature, 320°C; sheath gas pressure, 40 arbitrary units; auxiliary gas pressure, 10 arbitrary units; ion scans, 100--1,500 m/z; resolution of MS scans, 70,000; resolution of MS/MS scans, 17,500; and normalized collision energy, 10--70 eV. WEF (2.5--10 mg/mL) and mixtures (5--2,500 ng/mL) of authentic standards were prepared in methanol and filtered through a 0.22-μm filter membrane before injecting 3 μL aliquots for UPLC-MS/MS analysis. Scopoletin, as an internal standard, was


significantly less M2 protein than did untreated cells at 24 hpi (Figure [4A](#F4){ref-type="fig"}). The replication of GFP-expressing influenza (A/Puerto Rico/8/34) virus was significantly less in WEF-treated cells than in untreated RAW 264.7 cells (Figure [4B](#F4){ref-type="fig"}). Thus, these data indicate that WEF reduces influenza H1N1 viral protein expression and inhibition.

![Effect of WEF on the growth influenza A/PR/8/34 (H1N1) virus in RAW 264.7 cells. **(A)** Immunofluorescence analysis of influenza A M2 protein in cells. Cells were treated with WEF (10, 100 μg/mL) and IFN-β (1,000 U/mL) after influenza A virus infection. Influenza A virus M2-specific antibody was used for detection by fluorescence microscopy. Cells were also stained with DAPI, and the merged image shows the cytoplasmic location of the virus M2 protein (red). **(B)** RAW 264.7 cells were treated withimmunity, which is the ability of the human body to defend against infectious diseases, is becoming more important (Frieman et al., [@B8]) as new infectious diseases, such as avian influenza virus, Middle East Respiratory Syndrome (MERS), and Acute Respiratory Syndrome (SARS) infection, have emerged (Morens and Fauci, [@B21]). Because the occurrence of viral infection mainly occurs in a state of deteriorated immune function, various studies have been conducted to find natural products capable of enhancing these immune responses (Matsumoto et al., [@B18]; Wang et al., [@B33]; Singh et al., [@B26]; Choi et al., [@B5]).

Macrophages play a role in rapidly transmitting defense mechanisms against viral infections. When macrophages are activated during inflammatory reactions, they produce many inflammatory factors, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interferon-β (IFN-β) (Ellermann-Eriksen,


often not as strong as the misinformation itself. The analysis has several take-aways for fact-checkers, most notably the importance of creating counter-messages and alternative narratives if they want to change their audiences’ minds and getting on to the correction as quickly as possible.

Study Title

Debunking: A Meta-Analysis of the Psychological Efficacy of Messages Countering Misinformation

Twitter reflects the good, the bad and just plain ugly reality of social media these days. For academics, journalists and voters, there’s never been a more crucial time to talk about the impact these social media platforms have on factual journalism and being watchdogs of the powerful.

It’s in vogue to attack the messenger for the message. We are called liars. We are called “nasty people.” We are told to shut up.

Twitter just made it aQ:

Por que no funciona mi archivo javascript?

este es mi código:
<script src="resource_path('js/jquery-3.2.1.slim.min.js')"></script>
      <script type="text/javascript">
        $(function () {
          $('#ModalProducto').on('shown.bs.modal', function (e) {
            $('.focus').focus();
          })
        });
        @yield('jscript')
    </script>

Descargué el js porque necesito que esto funcione offline, si yo lo dejo de la siguiente forma el codigo funciona:
<script src="https://code.jquery.com/jquery-3.2.1.slim.min.js" integrity="sha384-KJ3o2DKtIkvYIK3UENzmM7KCkRr/rE9/Qpg6aAZGJwFDMVNA/GpGFF93hXpG5KkN" crossorigin="anonymous"></script>
      <script type="text/javascript">
        $(function () {


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asked 30 patients to fill in the 12-item OKS seven days later. During this period, they did not receive any major treatments that could substantially change their condition.

The ICC ranges from 0.00 (no agreement) to 1.00 (full agreement) describes the extent of answer repetition by the patients.

Internal consistency of the Persian OKS was evaluated by the Cronbach\`s alpha; it indicates good reliability when this index is between 0.7 and 0.9.^[@B18]^

Results
=======

The participants included 80 patients with a diagnosis of OA of three compartments of the knee by standing X-ray. They were 63 (79%) women and 17 (21%) men with a mean age of 52.2 years. Demographics of the patients are summarized in [table 1](#T1){ref-type="table"}.

######

Demographic Characteristic of the patients

  **Age**        and research. According to recommendations by Guillemin et al.,^[@B5]^ using a clinical measurement tool without validating the translated version can not suffice.

The aim of this study was to translate the site/disease specific 12-item patient-reported Oxford Knee Score into Persian with the focus on its validation. To our knowledge, this is the first study on the validation of the OKS among the Persian speaking population.

This version showed construct validity, reliability, internal consistency and content validity, similar to the original English OKS and its subsequent translated versions in other languages and cultures.^[@B12],[@B15],[@B19]^ The construct validity of the Persian version of the OKS was calculated by correlation between summed scores of the Persian OKS with the mean scores of different domains of the Persian SF-36 amongst our participants.

[Table 5](#T5){ref-type="table"} summarizes validation


studies of the OKS in the Persian, Portuguese, Dutch, Italian and Korean languages. Cronbach\`s alpha obtained in the test-retest reliability in the Italian, Dutch, Portuguese, French, Swedish and Singaporean (English, Chinese and Korean), Korean versions were 0.90, 0.94, 0.87, 0.88, 0.93, 0.8 and 0.91 respectively.^4,9,11,18,20,21^ In the present study, the high Cronbach\`s alpha coefficient (0.95) confirms the internal consistency of the OKS Persian version scale similar to the previous translations and cultural adaptations; therefore, we can conclude excellent reliability of the Persian OKS.

Regarding the ceiling effect in question 1, the probable cause could be due to the nature of the question as it inquires about pain. It is a fact that pain is a common finding in patients with knee problems and majority refer to clinics due tostratification usually store the dormant seeds on water-moistened substrates in darkness at low temperature (usually between 0 and 5 °C, typically 4 °C) ([@ref-22]; [@ref-24]; [@ref-2]; [@ref-8]). However, seeds of temperate-zone plants might encounter varying environmental conditions during this cold treatment. Surprisingly, few studies have tested effects of different environmental conditions during cold stratification on dormancy breaking and their interaction with conditions during subsequent germination stage ([@ref-3]; [@ref-28]; [@ref-33]). Seeds on the soil surface can be cold stratified in daily light-darkness cycles, while those buried in the soil will be stratified in continuous darkness. Different light conditions during cold stratification may differentially affect germination. For example, [@ref-3] reported that after one week of stratification, germination percentage of *Asclepias syriaca* was highest for seeds cold stratified in light then incubated in


China, *S. aralocaspica* is only found in saline desert of the southern margin of the Junggar Basin in Xinjiang Uygur Autonomous Region ([@ref-6]). Plants bloom in August and produce dimorphic seeds (non-dormant brown seeds and black seeds with non-deep physiological dormancy) on the same infructescence in September ([@ref-31]). Seeds are dispersed in October and germinate in the spring. Thus, seeds can be exposed to cold stratifying conditions during this period. Brown seeds can tolerate high levels of salinity (1,400 mmol L^−1^) during germination; black seeds germinate only under low salinity but still have the vigor after incubation at high salinity ([@ref-31]).

The aim of this study was to test the effects of light and salinity conditions during cold stratification and incubation stages on germination of dimorphic seeds of *S. aralocaspica*. We askedexplanation for the lack of promotion effect of cold stratification in salinity. Based on the fact that cold stratification and salt pretreatment are related to biosynthesis of GA ([@ref-9]; [@ref-21]), further work is necessary to analysis concentration of GA and the expression of related genes during pretreatment and germination periods.

Conclusions
===========

Non-dormant brown seeds and dormant black seeds of *S. aralocaspica* differentially respond to light and salinity conditions during and after cold stratification. The results suggest that each environmental factor during cold stratification may have the potential to influence subsequent seed germination. Furthermore, environmental conditions during cold stratification may interact with environmental conditions at germination stage. These results are in agreement with [@ref-34] suggestion that detailed studies of environmental condition during the period from seed dispersal to germination may show


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                  , f
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                        typename fusion::result_of::next<First1>::type, Last1>())));
        }
    }

    template <typename Pred, typename Sequence1, typename Sequence2, typename F>
    inline bool
    any_if_ns(Sequence1 const& seq1, Sequence2& seq2, F f, Pred)
    {
        return detail::any_if_ns<Pred>(
    Soluble human leukocyte antigen-G in seminal plasma is associated with HLA-G genotype: possible implications for fertility success.
We have previously shown that human seminal plasma contains immunomodulatory soluble HLA-G (sHLA-G). We investigated whether sHLA-G levels in seminal plasma are associated with a specific 14 base pair (bp) insertion/deletion (ins/del) polymorphism in the 3'-untranslated region of the HLA-G gene and/or with the outcome of assisted reproduction treatments (ART) in couples attending a fertility clinic. In a total of 54 unselected couples, sHLA-G levels were measured in seminal plasma samples and blood samples, HLA-G genotyping was performed, and clinical data were collected. The concentration of sHLA-G in seminal plasma samples was significantly associated with the HLA-G 14 bp ins/del genotype of the men; the del14 bp/del14 bp genotype showed the highest