diagrams has been already used [@BKK1; @BKK2] to study the anysotropic flows, and, in particular, the elliptic flow $v_2$ in collisions of hadrons and nuclei at high energies, questions so extensively discussed during this conference.

The significant differences observed in the yields of baryons and antibaryons in the central (midrapidity) region are connected with [@ACKS; @MRS] the special structure of baryons, consisting of three valence quarks together with a special configuration of the gluon field, called String Junction [@RV].

At very high energies, the contribution of the enhancement Reggeon diagrams becomes important, leading to the suppression of the inclusive density of secondaries [@CKTr] in the central (midrapidity) region.

The relative probabilities for the production of various baryons depend on the universal suppression factor S/L, for which we take the value, S/L = 0.32 [@AKMS], and theywe also present the QGSM prediction for the energy dependence of the $\Omega^-$ and $\overline{\Omega}^+$ hyperon production until LHC energies.

As one can see in Fig. 1, the absolute values of the densities $dn/dy(\mid y\mid \leq 0.5)$ for $\Lambda$, $\overline{\Lambda}$ production are one order of magnitude higher than for $\Xi^-$ and $\overline{\Xi}^+$ in a large energy region up to the LHC range. The same is also true for $\Omega^-$ and $\overline{\Omega}^+$ densities when compared to those of $\Xi^-$ and $\overline{\Xi}^+$.

-5pt

    $\sqrt{s}$ (GeV)                     Reaction                     QGSM


 19.42 (200 GeV/c)   p + Au $\to \overline{\Lambda}$   0.021         $0.013 \pm 0.06 $ [@NA35a]
   19.42 (200 GeV/c)         p + S $\to \Lambda$         0.041         $0.06 \pm 0.005 $ [@NA35b]
   19.42 (200 GeV/c)   p + S $\to \overline{\Lambda}$    0.016        $0.015 \pm 0.0025 $ [@NA35b]   Baby Bump, a Louisiana based maternity and children’s boutique, was determined to partner with Marcus Lemonis of “The Profit” and turn their business around. The company is owned and operated by husband and wife duo Robbie and Julie Allen. Their persistence in reaching out to Marcus 384 times via email is what ultimately caught his attention and landed them an opportunity to present their business to him.

Marcus was immediately drawn to Baby Bump because he felt that children’s apparel stores are a relatively safe bet and are mostly recession-proof, however, he quickly learned that Baby Bump was upside down in their finances by $135,000. Marcus was able to identify that while their profit margins were about 12% too low, they are still turning a profit with approximately $1


counsel. Wainwright v. Torna, 455 U.S. 586, 102 S.Ct. 1300, 71 L.Ed.2d 475 (1982).
The record indicates that at the time Sims was informed that the defendant wished to converse with Officer Kidd, Sims had no knowledge of the evidence that implicated defendant in the Cook murder and was still operating under the defendant's representations that he was in no way involved. We cannot hold that it was outside the range of reasonable professional representation for Sims to rely on the representations of his client as to his innocence and on the instructions of his client that he was not to be present at the interview with Officer Kidd. Nix, supra; see Phelps v. State, 435 So.2d 158 (Ala.Crim.App.1983) (counsel's advice that defendant make a statement to police nottestify: "The only person alive today that knows what happened out there that night is sitting right *1262 there." The defendant promptly objected to this remark and made a motion for mistrial.
We stated in Whitt:

"The comment `The only person alive today that knows what happened out there that night is sitting right there' is almost identical to the comment `No one took the stand to deny it' held to be a direct comment on the defendant's failure to testify and held to be reversible error in Beecher [v. State], 294 Ala. 674, 320 So.2d 727 (1975) (per Justice Embry). The comment is very close to the comment made in Warren v. State, 292 Ala. 71, 288 So.2d 826 (1973). There, this Court held (per Justice McCall) that the


that prevents a reversal of the case if the trial court sustains an objection to improper remarks and promptly and appropriately instructs the jury of the impropriety of those remarks. The trial court here overruled the objection, and we do not find the instruction given by the trial court here to be prompt, or to have been appropriately given. Here, the instruction given fails to clearly address or identify for the jury the exact statement made by the district attorney that was to be remedied. Absent such identification, the instruction can not be taken as "appropriately given" to address the state's impermissible argument.
At a minimum, under such circumstances, the trial judge should sustain the objection and immediately instruct the jury as to the impropriety of the remark madeu a prime number?
False
Suppose -59*a + 240*a - 7821553 = 0. Is a a composite number?
True
Suppose 50 + 158 = -8*c. Let w be (-4)/c + (-7619)/(-247). Is ((-2)/(-4))/(w/91574) composite?
True
Let q(s) = 3*s + 42. Let o be q(-20). Let d be o/(-27) + (-25)/(-3). Suppose 1784 = -k + d*k. Is k prime?
True
Suppose -19 = -9*b + 17. Suppose b*p = 2*p + 4856. Suppose 0 = 5*j + 3*y + y - 6073, 2*j - p = -y. Is j prime?
True
Suppose 5*m + 4*h - 42 = 0, -m = 2*m + 5*h - 33. Suppose m*z - 20447 = -z. Is z a composite number?
True
Suppose -5*d - 2*a = -51303 - 14690, -2*a + 52794 = 4*d. Is d a composite number?
True
Let w(c) = 5*c**2


4*b(r) - 11*q(r). Is o(-5) a composite number?
False
Let a(s) = 61*s**2 - 18*s + 28. Is a(25) composite?
True
Let h(g) = 5*g - 31. Let y be h(7). Let u be 655/95 - y/(-38). Suppose u*b + 11216 = 23*b. Is b a composite number?
False
Let n be (5/3)/(1/3). Let q(p) = 925*p + 6*p**2 - 927*p - 2 - 7*p**2 + 12*p**2. Is q(n) prime?
True
Suppose 18*a + 709720 - 40943 = 4023815. Is a a composite number?
False
Let m = -269604 - -535513. Is m prime?
False
Suppose 0 = 6*p - 39 + 3. Is (2/p)/((-41)/(-25953)) composite?
False
Let d be ((-8)/3)/((-6)/54). Suppose 15*z + 43587 = d*z. Is z composite?
True
Let x(u) = 417*u**2 + 1015*u - 9. Is x(-7) a prime number?
False
Let r be 12/(-60) - (-44)/20. Suppose r*i + 19*i -Caroline Elizabeth Merrick

Caroline Elizabeth Merrick (November 24, 1825 - March 1908) was an American writer and temperance worker. She is the author of Old Times in Dixie Land: a Southern Matron's Memories (1901).

Early life
Caroline Elizabeth Thomas was born on Cottage Hall Plantation, East Feliciana Parish, Louisiana, on November 24, 1825. Her father was Capt. David Thomas (1777-1849), who belonged to a prominent South Carolina family. A veteran of the Battle of New Orleans, David Thomas was a trustee of the college which later became the Centenary College of Louisiana. Her mother was Elizabeth Patillo, who died in 1833.

She was educated by governesses at home.

Career
Merrick devoted the first 20 years of her married life to raising a family. At that time, the temperance cause was being widely agitated in


the American Civil War, and was reelected under the Confederacy. Their family consisted of two sons and two daughters.

Merrick died in March 1908.

References

External links

Category:1825 births
Category:1908 deaths
Category:American temperance activists
Category:20th-century American women writers
Category:People from East Feliciana Parish, Louisiana
Category:20th-century American writers
Category:19th-century American women writers
Category:Wikipedia articles incorporating text from A Woman of the CenturyReedy $q$-cofibrant simplicial spectrum. It is straightforward to verify from the properties of the model structure in [@mmss] that such an $F(X_\bullet,Y)$ is always Reedy fibrant.

Finally, any cocyclic space $X^\bullet$ may be composed with ${\textup{sd}}_r$ to give an $r$-cocyclic space ${\textup{sd}}_r X^\bullet$. As before, the fixed points of ${\textup{Tot}}(X^\bullet)$ can be recovered as ${\textup{Tot}}(({\textup{sd}}_r X^\bullet)^{C_r})$:

If $X^\bullet$ is a cosimplicial space, there is a natural diagonal homeomorphism $${\textup{Tot}}(X^\bullet) \overset{D_r}{\longrightarrow}{\textup{Tot}}({\textup{sd}}_r X^\bullet)$$ If $X^\bullet$ is cocyclic, $D_r$ is $S^1$-equivariant.

\[cocyclic\_fixed\_points\] If $X^\bullet$ is a cocyclic space, then $({\textup{sd}}_r X^\bullet)^{C_r}$ may be regarded as a cocyclic space, and there are natural $S^1$-equivariant homeomorphisms $${\textup{Tot}}(({\textup{sd}}_r X^\bullet)^{C_r}) \cong \rho_r^*{\textup{Tot}}({\textup{sd}}_r X^\bullet)^{C_r} \overset{D_r^{C_r}}{\longleftarrow}\rho_r^*{\textup{Tot}}(X^\bullet)^{C_r}$$

The proofs are easy dualizations or direct copies of the proofs for cyclic spaces.

The suspension spectrum of $LX$.
--------------------------------

We end this section with a more concrete


the right-hand side, whose fibers are $$F^{C_{n+1}}(\Lambda^n/\partial \Lambda^n, \Sigma^\infty X^{{\wedge}(n+1)}) \simeq \Omega^n \Sigma^\infty X^{{\wedge}(n+1)} \vee \Omega^{n+1} \Sigma^\infty X^{{\wedge}(n+1)}.$$ Along the interchange map, this filtration can be shown to agree with Arone’s model of the Taylor tower for $\Sigma^\infty_+ LX$ from [@arone_snaith].

Orthogonal $G$-spectra, equivariant smash powers, and rigidity. {#sec:orthogonal}
===============================================================

We will now review the theory of orthogonal $G$-spectra and prove our rigidity theorem for the geometric fixed point functor $\Phi^G$. This result is a technical linchpin that underlies the rest of our treatment of cyclotomic spectra and the cyclic bar construction. It allows us to cleanly reconstruct and extend the model of $THH$ presented in [@angeltveit2014relative].

Basic definitions, model structures, and fixed points. {#gspectra_basics}
------------------------------------------------------

We take these definitions from [@mandell2002equivariant] and [@hhr].

If $G$ is a fixed compact Lie group, an *orthogonal $G$-spectrum*in fact there is natural diagonal map $$X \overset\Delta{\longrightarrow}\Phi^{C_n} X^{{\wedge}n}$$ When $X$ is cofibrant, this map is an *isomorphism*. More generally, if $G$ is a finite group, $H \leq G$, and $X$ is an orthogonal $H$-spectrum, we can define a smash product of copies of $X$ indexed by $G$ $$N^G_H X := \bigwedge_{g_iH \in G/H} (g_iH)_+ {\wedge}_H X \cong \bigwedge^{|G/H|} X$$ This construction is the *multiplicative norm* defined by Hill, Hopkins, and Ravenel. This can be given a $G$-action, which depends on some fixed choice of representatives $g_i H$ for each left coset of $H$ (cf. [@bohmann2014comparison], [@hhr]). Changing the choice of representatives changes this action, but only up to natural isomorphism. We therefore implicitly assume that such representatives have been chosen. The general form of the above


it does at level $m_1 + \ldots + m_k$: $$O(m_1 + \ldots + m_k)_+ {\longrightarrow}O(m_1 + \ldots + m_k)_+$$ This map, in turn, is determined by the image of the identity point, which is some element $P \in O(m_1 + \ldots + m_k)_+$. Now for any point $(t_1,\ldots,t_k) \in S^{m_1} {\wedge}\ldots {\wedge}S^{m_k}$ we can choose maps of spectra $F_{V_i} S^0 \to F_0 S^0$ which at level $V_i$ send the non-basepoint of $S^0$ to the point $t_i \in S^{m_i} \cong (S^{V_i})^G$. Since $T$ is a natural transformation, this square commutes for all choices of $(t_1,\ldots,t_k)$: $$\xymatrix{
O(m_1 + \ldots + m_k)_+ \ar[r]^-{\cdot P} \ar[d]^-{\textup{ev}_{(t_1,\ldots,t_k)}} & O(m_1 + \ldots + m_k)_+ \ar[d]^-{\textup{ev}_{(t_1,\ldots,t_k)}} \\
S^{m_1 + \ldots + m_k} \ar[r]^-{\textup{id}}& S^{m_1 + \ldots + m_k} }$$ Since $O(m_1 + \ldots + m_k)$ actsHill-Hopkins-Ravenel norm diagonal $${\textup{\textbf{{C}}}}(c_0,c_1) {\wedge}\ldots {\wedge}{\textup{\textbf{{C}}}}(c_{n-1},c_0) \overset{\Delta}{\longrightarrow}\Phi^{C_r}\left({\textup{\textbf{{C}}}}(c_0,c_1) {\wedge}\ldots {\wedge}{\textup{\textbf{{C}}}}(c_{n-1},c_0)\right)^{{\wedge}r}.$$ We want to show that these diagonal maps for each $n \geq 1$ assemble into a map of cyclic spectra $$N^{\textup{cyc}}_\bullet {\textup{\textbf{{C}}}} \overset\Delta{\longrightarrow}\Phi^{C_r} {\textup{sd}}_r N^{\textup{cyc}}_\bullet {\textup{\textbf{{C}}}}$$ (cf. [@angeltveit2014relative 4.6]). It easily commutes with most of the face and degeneracy maps because the diagonal is natural. One runs into issues with $d_0$ and $t_{rn-1}$, but these are fixed by the argument we used in Prop \[cmn\_is\_cmcn\]. In brief, the $r$-fold smash $(d_0)^{{\wedge}r}$ of $d_0$ from the cyclic structure is not the same map as $d_0$ in the $r$-cyclic structure, but they differ by the map $$f: \left({\textup{\textbf{{C}}}}(c_0,c_1) {\wedge}\ldots {\wedge}{\textup{\textbf{{C}}}}(c_{n-1},c_0)\right)^{{\wedge}r} {\longrightarrow}\left({\textup{\textbf{{C}}}}(c_0,c_1) {\wedge}\ldots {\wedge}{\textup{\textbf{{C}}}}(c_{n-1},c_0)\right)^{{\wedge}r}$$ that takes the factors ${\textup{\textbf{{C}}}}(c_{n-1},c_0)$ and cycles them while leaving all the other terms fixed. It suffices to


in the objects $c_0, \ldots, c_{n-1}$ then the orbit is of the form $(C_n)_+$ smashed with a pushout-product of cofibrations, so it is automatically a $C_n$-cofibration. When there is $r$-fold periodicity, the problem instead reduces to showing that an $r$-fold pushout-product of a single cofibration $f$ of orthogonal spectra becomes a $C_r$-cofibration $f^{\square r}$. Since $\square$ preserves retracts, it suffices to show that if $f$ is a cell complex of orthogonal spectra then $f^{\square r}$ is a cell complex of orthogonal $C_r$-spectra.

In fact, it is a cell complex of orthogonal $\Sigma_r$-spectra. The argument for this is tedious but very formal. It holds because the categories of orthogonal $G$-spectra with varying $G$ satisfy the following assumptions: the domains of our $G$-cells are small with respect to relative cell complexes;are not isomorphic as simplicial objects, they have the same degeneracy maps and therefore have isomorphic latching maps. The cofiber of this latching map $$({\mathbb S}{\longrightarrow}(cDX)^{{\wedge}r})^{\square k} \square (* {\longrightarrow}(cDX)^{{\wedge}r})$$ is the smash product of $k$ copies of the $C_r$-equivariant cofiber of ${\mathbb S}{\longrightarrow}(cDX)^{{\wedge}r}$ and one copy of $(cDX)^{{\wedge}r}$. The $C_r$-equivariant dual of this is a smash product of $k$ copies of $\Sigma^\infty X^r$ and one copy of $\Sigma^\infty_+ X^r$.

To evaluate the homotopy fiber of the map of our homotopy limit system $$F(|{\textup{Sk}}_k {\textup{sd}}_r N^{\textup{cyc}}_\bullet cDX|,f{\mathbb S}) {\longrightarrow}F(|{\textup{Sk}}_{k-1} {\textup{sd}}_r N^{\textup{cyc}}_\bullet cDX|,f{\mathbb S}),$$ we observe that it is the dual of the cofiber of the inclusion of skeleta. By the usual latching square, this cofiber is the $k$-fold suspension of the cofiber of the latching map. Therefore our desired


question, so that the dataset is useful for a wide range of purposes. The choice of dataset representation is made to give some theoretical guarantees on this “information content”.

Contributions and outline {#subsec:introduction:outline}
-------------------------

The main contributions of this work are:

-   MUSCIMA++[^5] – an extensive dataset of handwritten musical symbols,[^6]

-   A principled ground truth definition that bridges the gap between the graphical expression of music and musical semantics, enabling evaluation of multiple OMR sub-tasks up to inferring pitch and duration both in isolation and jointly;

-   Open-source tools for processing the data, visualizing it and annotating more.

The rest of this article is organized into five sections. In section \[sec:groundtruth\], we describe the OMR pipeline through input-output interfaces, in order to design a good ground truth foryet respond to the needs of the OMR community, especially since most machine learning efforts have been directed to this stage; see section \[sec:existingdatasets\].

In turn, the list of locations and classes of symbols on the page is the input to the [**music notation reconstruction**]{} stage. The outputs are more complex: at this stage, it is necessary to recover the relationships among the individual musical symbols, so that from the resulting representation, the “musical content” (most importantly, pitch and duration information – what to play, and when) can be unambiguously inferred.

There are two important observations to make at stage 3.

First, with respect to pitch and duration, the rules of music notation finally give us something straightforward: [*there is a 1:1 relationship between a notehead notation primitive and a note


noteheads and stems do not touch, accidentals and noteheads [*do*]{} touch, etc. However, some writers are more disciplined than others in this respect. The various styles of handwriting, and the ensuing challenges, also have to be represented in the dataset, as broadly as possible. As there is currently no model available to synthesize handwritten music scores, we need to cover this spectrum directly through choice of data.

We find [**adherence to topological standards**]{} to be a more general term that describes this particular class of difficulties. Tightness of spacing is a factor that globally influences topological standardization in printed music; in handwritten music, the variability in handwriting styles is the primary source of inconsistencies with respect to the rules of CWMN topology. This variability includes the difference between contemporarywhich has proven to be quite time-intensive to annotate manually, but no symbol annotations (it has been mentioned in [@Fornes2012] as future work). The dataset also fulfills the requirements for a good choice of data, as described in \[sec:choiceofdata\]. With respect to notation complexity, the 20 pages of CVC-MUSCIMA include scores of all 4 levels, as summarized in table \[tab:existingdatasets:cvcmuscima\] (some scores are very nearly single-voice per staff; these are marked with a (?) sign to indicate their higher category is mostly undeserved). There is also a wide array of music notation symbols across the 20 pages, including tremolos, glissandi, an abundance of grace notes, ornaments, trills; clef changes, time and key signature changes, and even voltas and less common tuples are found among the music. Handwriting style


refined the ground truth definitions.

As noted above, each annotator completed one image of each of the 20 CVC-MUSCIMA pages. The work was dispatched to annotators in four packages of 5 images each, one package at a time. After each package submission by an annotator, we checked for correctness. Automated validation was implemented in MUSCIMarker to check for “impossible” or missing relationships (e.g.: a stem and a beam should not be connected; a grace notehead has to be connected to a “normal” notehead). However, there was still need for manual checks and manually correcting mistakes found in auto-validation, as the validation itself was an advisory voice to highlight questionably annotated symbols, not an authoritative response.

Manually checking each submitted file also allowed for continuous annotator training and filling in “blindtook roughly 400 hours of work; the “quality control” correctness checks took an additional 100 – 150. The second, more complete round of quality control took roughly 60 – 80 hours, or some 0.5 hours per image.[^38]

Inter-annotator agreement {#subsec:data:agreement}
-------------------------

In order to assess (a) whether the annotation guidelines are well-defined, and (b) the extent to which we can trust annotators, we conducted a test: all seven annotators were given the same image to annotate, and we measured inter-annotator agreement. Inter-annotator agreement does explicitly not decouple the factors (a) and (b). However, given that the overall expected level of ambiguity is relatively low, and given the learning curve along which the annotators were moving throughout their work, which would as be hard to decouple from genuine (a)-type disagreement, we opted


to not expend resources on annotators re-annotating something which they had already done, and therefore cannot provide exact intra-annotator agreement data.

Another use of inter-annotator agreement is to provide an upper bound on system performance. If a system performs better than average inter-annotator agreement, it may be overfitting the validation set. (On the other hand, it may have merely learned to compensate for annotator mistakes – more analysis is needed before concluding that the system overfits. But it is a useful warning: one should investigate unexpectedly high performance numbers.)

### Computing agreement

In order to evaluate the extent to which two annotators agree on how a given image should be annotated, we perform two steps:

-   Align the annotated object sets against each other,

-   Compute the macro-averaged f-scoreor more symbols that are not stafflines, and a $0$ in all other cells, and if opened in an image viewer, it looks like white-on-black results of staffline removal.

[^22]: <http://www.cvc.uab.es/cvcmuscima/index_database.html>

[^23]: It should also be noted that HOMUS is not available under an open license, so copyright restrictions apply. Not even every EU country has the appropriate “fair use”-like exception for academic research, even though it is mandated by the EU Directive 2001/29/EC, Article 5(3) (<http://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX:32001L0029>).

[^24]: <https://www.imslp.org>

[^25]: <http://www.mutopiaproject.org>

[^26]: <http://humdrum.ccarh.org>

[^27]: With the exception of writer 49, who is represented in 4 images due to a mistake in the distribution workflow that was only discovered after the image was already annotated.

[^28]: The choice of test set images is provided as supplementary data, together with the dataset itself.

[^29]: The most complete annotation


guidelines detailing what the symbol set is and how to deal with individual notations are available online: <http://muscimarker.readthedocs.io/en/develop/instructions.html>

[^30]: As seen in page 20 of CVC-MUSCIMA.

[^31]: We would go as far as to say that it is inadequate to try marking “note” graphical objects in the musical score. A note is a basic unit of [*music*]{}, but it is not a unit of music [*notation*]{}. Music notation [*encodes*]{} notes, it does not [*contain*]{} them.

[^32]: Even though this does not occur in CVC-MUSCIMA, it does happen, as illustrated e.g. by Fig. 8 in [@Byrd2015].

[^33]: <https://github.com/hajicj/muscima>

[^34]: <https://github.com/hajicj/MUSCIMarker>

[^35]: <https://lindat.mff.cuni.cz/repository/xmlui/handle/11234/1-1850>, ongoing development at <https://github.com/hajicj/MUSCIMarker>

[^36]: Basic usage is described in the MUSCIMarker tutorial: <http://muscimarker.readthedocs.io/en/develop/tutorial.html>

[^37]: <https://www.teamviewer.com>

[^38]: For the sake of completeness, implementing MUSCIMarker took about 600 hours, including the learning curve for the GUI framework.

[^39]:Q:

sizeof(*this) gives wrong value

I have a class, C. C has a member variable declared as: bool markerStart;
From within C a call to sizeof(*this) gives a value of 0x216 bytes.
Elsewhere within C, I do: markerStart = false;
Rather than setting markerStart to false, this call is actually clobbering the start of the next class in memory!
Looking at the disassembled code, I find:
markerStart = false;
06FB6B7F mov            eax, dword ptr [this]
06FB6B78 mov            byte ptr [eax+218h], 0

The second move instruction is setting a byte at this + 0x218 to zero, but since the class is only 0x216 bytes long, this is clobbering memory!
In response to a comment, it definitely is the


cell lines lacking XBP1 exhibit attenuated tumorigenesis due to impaired assembly of XBP1/HIF-1 transcriptional complex and substantial inhibition of downstream hypoxia-responsive genes expression (Chen X. et al., [@B25]). In addition, it has been reported that co-occupancy of the promoter region of vascular endothelial growth factor A (VEGFA) by ATF4, XBP1, and HIF-1 is indispensable for its expression (Pereira et al., [@B138]). Given the significance of tumor vascularization for its growth and relapse, it is appealing to further study HIF-1 and UPR co-responsiveness in tumorigenesis. Whether autophagy and XBP1/HIF-1 transcriptional co-occurrence are interrelated with tumorigenesis under the conditions studied, remains to be determined. In this context, interactions between autophagy and ATF6-dependent expression of CHOP and XBP1 have also been documented (Mei et al., [@B121]). Arguably, the IRE1/XBP1 and ATF6Beclin1 is active to induce autophagy while BNIP3 and BNIP3L are now "occupied" by BCL-xL/Bcl-2. Additionally, formation of the latter complexes inhibits cell death upon hypoxia (Bellot et al., [@B7]). The BH3 domains of these factors are critical for the formation of these complexes both in normoxia and hypoxia.

Additionally, it has been shown that BNIP3 physically interacts with Ras homolog enriched in brain (RHEB) and triggers a reduction of the RHEB GTP levels, thus inhibiting S6 kinase phosphorylation at Thr389 and ultimately mTOR (Li et al., [@B100]). This is another mechanism through which BNIP3 triggers general autophagy induction upon hypoxia. Further, it has been proposed that increased expression of BNIP3 and NIX in response to hypoxia causes mitochondrial depolarization and generalized mitochondrial dysfunction (Rikka et al., [@B146]). This,


Drp1 dissipates in the cytoplasm. Upon hypoxia, on the other hand, BNIP3/NIX are highly expressed in a HIF-1-dependent manner. Increased BNIP3/NIX abundance on the OMM triggers Bcl-2/Beclin and BCL-xL /Beclin complex dissociation. Particularly, BNIP3 and NIX are bound on either BCL-xL or Bcl-2, rendering Beclin free to trigger autophagy induction. General autophagy induction could in turn trigger mitophagy. Additionally, BNIP3/NIX accumulation on the OMM triggers mitochondrial dysfunction and membrane depolarization. This leads to excessive ROS production, which can also activate general autophagy. Moreover, BNIP3 binds Rheb, thus diminishes the amount of "free"/cytoplasmic Rheb-GTP and inactivates mTOR, inducing again general autophagy. Concomitantly, BNIP3/NIX phosphorylation and dimerization triggers LC3 binding and finally mitophagy induction. It is also conceivable that Drp1 triggers mitochondrial fragmentation by translocating on the OMM. miR-137 levelsdrop. In the bottom half of the Figure, processes that take place under normoxia are illustrated and in the top half, processes under hypoxia. The axis in the left part of the Figure is representative of the available oxygen concentration.](fcell-06-00104-g0003){#F3}

Hypoxia-induced degradation of other organelles {#s4}
===============================================

The wide variety of metabolic alterations induced by hypoxia are expected to totally reorganize cellular function and affect several if not all cellular compartments in terms of abundance and/or function. Hence, additional targets other than mitochondria are expected to be regulated through selective autophagy upon hypoxia. Toward this direction, evidence exists that selective autophagy of the nucleus (nucleophagy), lipids (lipophagy), ribosomes (ribophagy), ER (ERphagy or reticulophagy), and/or peroxisomes (pexophagy) are activated upon hypoxic stimuli (Carloni et al., [@B16]; Chen K. et al., [@B20]; Rashid


vasculogenesis and angiogenesis (Krock et al., [@B86]). Thus, cells are locally supplied with oxygen and nutrients, boosting their previously stalled proliferation. This is a never-ending phenomenon, as proliferation would again raise oxygen needs, re-creating a hypoxic microenvironment in a constrained part of the tumor due to the local, abrupt expansion of cells. This re-activates HIFs further promoting tumor expansion, aggressiveness, metastasis, and drug resistance. Taking into account the importance of HIF-1 responses in tumor progression and patient prognosis, it is crucial to gain deep understanding of the mechanisms that are activated downstream of HIFs.

Selective autophagy components in cancer {#s6}
========================================

The cell adapts to hypoxic stimuli through the activation of delicate mechanisms which converge on autophagy for recycling of unwanted components or/and organelles, contributing to the preservation of homeostasis. Dysfunctionimmunotherapy (Buart et al., [@B12]). The effect of BNIP3 does not seem to equally apply in every type of breast tumor. In contrast to other studies, in breast cancer cells, BNIP3 deletion promotes metastasis and is linked with poor prognosis in human triple-negative breast cancer (TNBC). In addition, downregulation of the tumor suppressor retinoblastoma protein highly induces BNIP3 expression under hypoxic conditions (Tracy et al., [@B173]). On the other hand, the tumor suppressor p53 can directly bind to the BNIP3 promoter and block its expression both under normoxic and hypoxic conditions, thereby inhibiting hypoxia-induced BNIP3-autophagy induction (Feng et al., [@B48]). Since BNIP3 and NIX are both involved in mitophagy and apoptotic cell death, it is possible that their role may vary depending on the tumor type. For example,


Deeper analysis showed that in this type of cancer cells, FAM134B was inactivated through promoter methylation and interestingly this effect was found to be tumor stage---specific, i.e., late-stage cancer cells exhibited increased FAM134B promoter methylation in comparison to earlier ones (Islam et al., [@B68], [@B67]). Moreover, in colon cancer cells, an alternative FAM134B inhibition pathway through miR-186-5p, has been revealed rendering FAM134B a tumor suppressor, at least for this type of tumor (Kasem et al., [@B74]; Islam et al., [@B68]). Additionally, FAM13B is mutated in about half of the colorectal cancer samples tested compared to their healthy counterparts. Different types of mutations were identified ranging from single-nucleotide substitutions to insertions and deletions, among others (Kasem et al., [@B74]; Islam et al., [@B68]). Mutations on FAM134B have been identifiedEnglish, American (one day), Author, Journalist & Filmaker

The Trump Show -Fear, Frenzy & Food Trucks

Love him or loath him Donald Trump is far exceeding most pundits’ wildest expectations. He has the GOP establishment terrified and appears to have struck a chord with a specific section of society deeply upset by business as usual, gridlocked Washington politics.

On Friday February 12th 2016 Mr. Trump held a rally at the University of South Florida Sun Dome Arena. I felt I owed it to myself to attend. I wanted to experience and see for myself what it was like and more importantly what his supporters were like.

The first thing I noticed were food trucks. With a large crowd of people standing patiently in line going nowhere fast and getting hungry it was


concert as it did a political rally.

I next approached a rather large burly white guy holding a “Build the Wall” sign and asked him what his key issue was? “Immigration,” he replied telling me it was time to “Build the wall,” a popular chant among many that evening. When I asked the gentleman’s name he told me his first name willingly but when asked his last he paused and responded “I’d rather not say”. I got the sense the big fella realized his last name of ‘Fitzgerald’ or ‘Schmidt’ or whatever other historically immigrant last name he may have, would not jive well with his anti immigration stance.

After running into a Trump look alike ‘performing’ for a jubilant crowd I came across a group of young men withof sound and d is the streamer depth. Seismic streamers have been conventionally towed at a depth of 10 m or less. At a depth of 10 m, the notch frequency (fnotch) is 75 Hz. A frequency response extending beyond 100 Hz is required for high seismic image resolution. Because the notch frequency is inversely proportional to the tow depth, streamers are often towed at shallower depths to improve the resolution of a seismic image. Towing at shallow depths is problematic because noise from the sea surface begins to interfere with the desired seismic signals. These effects are worsened as weather deteriorates, sometimes causing the crew to discontinue operations until the weather improves. The elimination of ghost-notch effects would enable towing at greater depths farther away from surface


Q:

Highcharts - Organizing the raw data

I'm looking at all the demos of highcharts and they all seem to follow a very simple data structure:
Categories,Apples,Pears,Oranges,Bananas
John,8,4,6,5
Jane,3,4,2,3
Joe,86,76,79,77
Janet,3,16,13,15

I have data that doesn't fit this organization very well. I could do it this way of course but it would be a pain to set up and impossible to update.
I'm looking to build stacked bar chart that shows categories (say  Group1, Group 2,  Group 3) and sales staff with their sales. The problem gets complicated as sales staff can be in more than one group at one time; and as this goes over time can return to the original category.
So Category 1 (Group 1) will be pulling data from a table like that below
Date  |  Date | Group |
Start |12/14/2006  516 jt
Cherries 3/11/2006  7/15/2006   126 fs
Cherries 7/15/2006  4/28/2007   287 jc
Cherries 4/28/2007  9/1/2012    1953    fs
Cherries 10/14/2010 11/2/2012   750 gg
Cherries 9/1/2012   11/2/2012   62  dg
Cherries 11/2/2012  2/3/2015    823 gg

At this point I don't see how to work with highchart. Can anyone point to a way to use tables such as that listed above?
SEE Fiddle of what it should look like:
http://jsfiddle.net/MAYO/eLam1Lo1/5/

A:

This question has far more to do with data organization and representation in general than it does with anything highcharts specific.
You need to work out the details of how important the different aspects of the data are, and what about them you want to show,


How to keep your pipeline contacts nurtured

“Call us back in about six months’ time…”

How often have you appraised Mr & Ms Vendor’s property and they’ve told you they’re not quite ready to list just yet … you have every intention of keeping in touch (after all you had such great rapport) … life gets in the way … and then you see a signboard on their front lawn…?

You took them at their word – that you were the one because they just:

Wanted to do some minor redecorating before they listed

Wanted to list when the garden was looking its best…

They’re waiting for Jupiter to align with Mars…

Whatever their reason for not listing at the time of your appraisal meeting, the end result means you didn’t walk away with a       m_{\text{DEC}\rightarrow d}(d_{k,j}) \propto \mathcal{B}\left( p_d^a \right),\,
        m_{\text{DEM}\rightarrow d}(d_{k,j}) \propto \mathcal{B}\left( p_d^e \right). \label{eq_FN_to_d}
    \end{aligned}$$ During the message passing procedure, the characteristic parameters of these distributions are updated following a selected schedule. For Bernoulli distributions, it is rather preferable to work with bit LLRs, rather than the success probability $p_d$: $$L(d_j) \triangleq \ln\frac{\mathbb{P}[d_j=0]}{\mathbb{P}[d_j=1]} = \ln\frac{1-p_d}{p_d}.$$ We use $L_a(\cdot)$, $L_e(\cdot)$ and $L(\cdot)$ operators to denote respectively a priori, extrinsic and a posteriori LLRs. When applied to $d_{k,j}$, this vocabulary represents the receiver’s perspective, i.e. $L_a(d_{k,j})$, $L_e(d_{k,j})$ respectively characterize $m_{\text{DEC}\rightarrow d}(d_{k,j})$ and $m_{\text{DEM}\rightarrow d}(d_{k,j})$.

Finally, considering the factor graph shown on Fig. \[fig\_fg\_rec\], all variable nodes are only connected to a pair of distinct factor


    q_\text{DEM}(x_k) = \textstyle  \sum_{\mathbf{d}_k} & \textstyle  f_\text{DEM}(x_k, \mathbf{d}_k)
            m_{x \rightarrow \text{DEM}}(x_{k})\\
            & \textstyle \prod_{j=0}^{q-1} m_{d \rightarrow \text{DEM}}(d_{k,j}).
        \end{split}$$ $$q_\text{DEM}(x_k) = \textstyle   \sum_{\mathbf{d}_k} f_\text{DEM}(x_k, \mathbf{d}_k) m_{x \rightarrow \text{DEM}}(x_{k})
        \prod_{j=0}^{q-1} m_{d \rightarrow \text{DEM}}(d_{k,j}).$$ This is a posterior categorical PMF on the elements $x_k$ of $\mathcal{X}$, which can be computed using eqs. (\[eq\_equ\_to\_x\]) and (\[eq\_priors\]), which will be denoted as $$\mathcal{D}_{k}(\alpha) \propto \exp{\left(-k_w{|\alpha-x^e_{k}|^2}/{v_k^e}\right)}\mathcal{P}_{k}(\alpha),\, \forall \alpha\in\mathcal{X}. \label{eq_posteriors}$$ For computing messages towards EQU, the posterior PMF is projected into $\mathcal{CN}$ through moment matching. The mean and the variance ofThe extrinsic feedback from the demapper is obtained by using jointly the prior information from the previous TI, and the past equalizer outputs of the current and previous self iterations (see (\[eq\_posteriors\])-(\[eq\_demap\_ep\_damp\_stats\_new\])). The Algorithm \[algo:fdsidfeicep\] also incorporates a mechanism to deal with EP-based feedback’s infamous negative variances [@senstAscheid_2011_frameworkEP_MMSEMIMO; @santosMurilloFuentes_2017_EPBLE], with the set $\mathcal{I}^{(s)}_\text{err}$ which stores their indexes. These values are replaced with APP-based variances in the current SI, and then replaced again with their previous values for the next SI.

;

(nAux0) at (demap) ; (nAux1) at (soft) ; (nAux0) -| (nAux1) -| (nAux0) ;

(nAux0) at (dummy\_1) ; (nAux1) at (dummy\_1) ; (nAux2) at (dummy\_2) ; (nAux3) at (dummy\_3) ; (nAux03) at (dummy\_3) ; (nAux4) at (dummy\_4) ; (nAux1) -| (nAux2) -| (nAux3) -| (nAux4) -| (nAux1) ;

(dummy\_chanest\_in) – node\[pos=0,xshift=-0.3cm\][$\sigma_w^2$]{}(nAux0);


achievable rates are also accurately computed. For turbo FIR, upper bounds are obtained by combining results of area theorem with the channel SIR. Tightness of this bound depend on the closeness of true MI trajectories to EXIT charts in Fig. \[bpskProakisC\_EXIT\_DFEIC\], so APP feedback’s asymptotic performance is likely to be overestimated compared to EP feedback.

Finite-Length Comparison with Existing Schemes {#ssec_dfeicberanalysis}
----------------------------------------------

Monte Carlo integration remains the most reliable analysis approach joint detection of BPSK symbols is considered with parameters in section \[ss\_rapidanalysis\], and $K_u=2048$, coded with a terminated $[7,5]_8$ RSC code. Bit error rate (BER) of various receivers are plotted in Fig. \[berandConvergenceBPSK\_proakisC\]. For the reported iterations, the DFE-IC APP outperforms other APP feedback DFE structures, and their convergence speeds are compared on the right side of the figure, atintermediary iterations. At 3 bits/s/Hz configuration (16-QAM with rate 3/4 code), with 5 TI and 3 SI, DFE-IC requires 3 dB less energy, and 3 times less computational resources than BLE-IC. With $\tau=s=0$, LE-IC is unable to decode, BLE-IC decodes around 39 dB, and DFE-IC decodes with 13 dB less energy.

These numerical results confirms conclusions drawn by the asymptotic analysis; the proposed SI DFE-IC is of a significant interest for high data rate applications where linear structures are less efficient. Using the efficient implementation method of section \[sec:matrixinvcholesk\], DFE-IC outperforms prior work in terms of both complexity and performance.

Conclusion
==========

This paper investigates on the use of decision feedback with turbo equalization, for improving the limitations of linear equalizers for high data rate applications.

Turbo DFE structures in the literature consist in either using hard


adjust the treatment in time, by means of the result of a re-biopsy \[[@B4]\].

A CT- guided needle biopsy is a valuable diagnostic tool for the diagnosis of pulmonary nodules and has only few serious complications, except for pneumothorax, which is seen in 1/3 of the patients undergoing this procedure \[[@B5]\]. Although small tumours have the best prognoses, these are more difficult targets to hit with a CT-guided transthoracic needle biopsy, the sensitivity of the procedure thereby being lower. The position of a suspicious pulmonary nodule, e.g. behind a rib, or close to the diaphragm can make it difficult to perform a biopsy, and respiratory movements may hamper it further.

For this, and similar procedures demanding a pulmonary standstill, several alternatives to breathing have been suggested over the years, includingOrganon Ltd, Dublin Ireland) was used to monitor the neuromuscular block. After 2 minutes of pre-oxygenation with 100% oxygen, the ventilation mode was switched to a continuous positive airway pressure (CPAP) of 5--10 cm H~2~O, maintaining 100% oxygen delivery without ventilation. The patient was continuously observed with pulse oxymetry (Dräger Medical GmbH, Lübeck, Germany). If the position of a lung nodule precluded a biopsy, the pressure was increased according to our schedule, not higher than 20 cm H~2~O. The highest value in this small study was 17 cm H~2~O, which expanded the lung to a much better biopsy position. After retrieving the biopsy, controlled ventilation was re-established and a concluding CT-scan was performed to reveal a possible pneumothorax. In case of a clinical symptomatic pneumothorax a chest tube Charrière 18 was inserted.


stereo image processing can be point clouds, which are sets of independent single estimates in three-dimensional space. Point cloud representations lead to scene descriptions that are disjoint, statistically noisy, and not representative of the smooth and continuous nature of our world or the objects in it. Processing point clouds with an averaging and filtering process to derive more continuous descriptions can result in errors, since this processing is not based on real world constraints. Point clouds cause problems when mapping image data as a texture, since a texture is continuous by nature but a point cloud is discrete. The present disclosure describes systems and methods for representing the results of stereo image processing using connected elements that provide a description of the relationship between estimates and their neighborsease. It stands near 81 basis points [on May 5], the lowest since last June.

These metrics reflect the easing of the strains in the financial sector. With more data showing some improvement and officials talking about economic green shoots, there is strong interest in the reflation story.

Edward Yardeni, Yardeni Research

What's next for stocks now that the S&P 500 is back to 907.24, i.e., essentially unchanged for the year? Remember all those terrible problems that knocked the S&P 500 down to the intraday low of 666 on Mar. 6? Well, never mind. The market is up 36% from that low. Is the relief rally over? Not necessarily. What if payroll employment is down "only" 300,000? The S&P 500 could easily jump to the Jan. 6 closing high of the


The quinolines PK 8165 and PK 9084 possess benzodiazepine-like activity in vitro but not in vivo.
The quinolines PK 8165 and PK 9084 bind to brain benzodiazepine receptors in vitro. However, unlike diazepam, these molecules do not reduce GABA turnover, possess anxiolytic properties, or displace [3H]flunitrazepam from benzodiazepine receptors in vivo. The pharmacological properties of PK 8165 and PK 9084 in vivo are thus unrelated to the benzodiazepine receptor.Q:

PHP/MYSQL SEARCH QUERY RETURNS ERROR: Subquery returns more than 1 row

please I am totally new to mysql, my problem is:
I have a table called 'cong' which has the following columns(id, sort_code, pin, name, state, lga, zip, address, min, min_photo, sec, min_phone, sec_phone) which contains all congregations.
The columns (state, lga) contains the id from the tables 'states' and 'local_govt'.
The 'states' table has the following columns (id, country_id, name), and the 'local_govt' table has the following columns (id, country_id, state_id, name).
I want to carry out a search on the 'cong' table which should search through the 'state' and 'local_govt' tables for matches, below is the search function I wrote:
      <?php
      function find_cong($term) {
      $query =


 $query .= " OR upper(sec) rLIKE '{$term}'";
      $query .= " OR upper(min_phone) rLIKE '{$term}'";
      $query .= " OR upper(sec_phone) rLIKE '{$term}'";
      $result = mysql_query($query);
      confirm_query($result);
      return $result;
      }

      function confirm_query($query) {
          if (!$query) {
             die("Database query failed : " . mysql_error());
          }
      }

      ?>

The problem now is that, it searches some termsthat his actions “constitute clear proof” that he insulted the Prophet Muhammad and should be sentenced to death. On September 4, 2013, judiciary officials sentenced Arabi to three years in prison for “propaganda against the state” and “insulting the Supreme Leader” in a separate case stemming from the same Facebook posts.

Naimi said that her husband’s interrogators subjected him to psychological pressure and threatened to prosecute and convict him if he did not take responsibility for posting offensive material on his Facebook page. She said the first time Arabi was able to meet with his lawyer was just before his trial, though judiciary officials allowed his lawyer to review the case file prior to mounting a defense. She said she has yet to tell their 5-year-old daughter that her


and Iranian Americans ($72,733) also out-earned whites.

In general, the U.S. Census Bureau reports that Asians have had a higher median household income than whites since the mid-1980s. In fact, figures from the Bureau of Labor Statistics indicate that white men earned 80 percent of what Asian men earned in 2017.

The economic gap between whites and Hispanics seems to be dissipating, as well. According to a study by Stanford, Harvard, and Census Bureau researchers, the incomes of white and Hispanic households will soon converge, with some 45 percent of Hispanics who grew up in poverty making it to the middle class or higher, compared to 46 percent of whites. Furthermore, the median income for Hispanic households rose for the third straight year, increasing 3.7 percent in 2017, outpacing thechip with the 7nm process, it could be roughly 40 percent smaller, and use either 40 percent less power running at the same speed, or run at a 20 percent higher clock speed at the same power.

As Cross notes, a like-for-like comparison ignores the fact that the A12 will, of course, be a more complex chip, and is unlikely to be able to push the clock-speed much, but extrapolating typical year-on-year improvements still suggests some impressive numbers. Cross says that you do, however, have to take account for the big jump in the A11 performance, which is unlikely to be replicated this year.

The A11 made a major architectural change to the way multi-threaded performance works. It introduced a new second-generation performance controller that, for the first time, allowed


likely to be around 15-25%.

Apple has aimed for pretty consistent battery life, so the theoretical improvements to be gained from the 7nm process are likely to be offset by the greater demands the company will make on the A12 chip. But there could be one piece of good news.

The “screen on time” battery life of the new iPhones will be as much about the battery capacity, display efficiency, and radio efficiency as it will be about the A12. But we’ll go out on a limb and say that idle battery life (already a strong suit of iPhones) is going to be killer, and that the presumably larger battery in the new Plus sized iPhone will give it a real advantage over this year’s iPhone X. A more efficientcellular radio should improve battery life, too.

Finally, Cross speculates that the switch to Intel modems could, for the first time, mean a single world iPhone, rather than the modem variants currently seen around the globe to accommodate different cellular technologies and bands. That would be good for travellers, and also provide Apple with a slightly simpler supply-chain.

Check out 9to5Mac on YouTube for more Apple news:

FTC: We use income earning auto affiliate links. More.

Check out 9to5Mac on YouTube for more Apple news:


who also faces problems in another case.

"The Justice Department announced in March that it would pursue civil fraud claims against Mr. Gabelli, arguing that he orchestrated a scheme to deceive the Federal Communications Commission in its auctions of wireless spectrum licenses several years ago. He has denied the accusations.

"In a statement yesterday, Mr. Gabelli said that Mr. Mancheski and Mr. Perlmutter would receive about 2.1 million Gamco shares worth about $80 million, which would correspond with their stake in Gabelli Group Capital Partners.

"Additional cash compensation, worth more than $20 million, is also expected to be paid as part of the deal, though the details of that part of the settlement could not be learned...."

What perhaps should also be noted is that Columbia University Business School Expansion Project Funderwe dropped Crysis 3 down from very high to high in our initial test).

At 1440p, we would expect the 384-bit memory bus of the R9 280 to show a more sustained advantage up against the 256-bit and 128-bit interfaces of the R9 380 and GTX 960 respectively, but the reality is that all of the cards we tested scale up fairly well. However, once again, the numbers don't do justice to the reality of the 2GB/4GB divide between the two R9 380s. Latency spikes are even more pronounced on the affected games, with Far Cry 4 in particular suffering badly on the 2GB model - far more so than the 2GB GTX 960, curiously.

The good news for those looking for a bargain is that while the R9 280


XFX. Also interesting is that power consumption on the older R9 285 is higher, despite its slower clocks. Again, this could be down to a different board design, but equally, it may well be the case that AMD has slightly tweaked the Tonga processor design for the 300 series refresh to make it a little more power efficient.

The old Tahiti-powered R9 280 is the most power hungry card out of the batch, but the XFX Double Dissipation version we have is a remarkably sturdy and well-built card that we still recommend highly - curiously, it is a lot quieter than the R9 380 we have on test here, despite the higher power consumption. Even so, despite the age of the Tahiti processor and its reputation for heat generation,wifi RTT to the metropolitan core is 15 ms, and over LTE it is 47
ms. Not a worthwhile tradeoff at 40 ms unconditional additional RTT delay.

I imagine the higher latency was used to offset lower bandwidth due to FEC
encoding loss, by amortizing it over more bits.

------
codex
What's funny here is that wireless networks already use FEC at the physical
layer. This just adds more, less conservative, FEC higher up for apps where it
makes more sense to reduce throuhput and increase some average case latency to
avoid worse case latency and worse case throughput.

------
liamzebedee
My friend did something similar to the concepts in this article, except he
applied it to compression of audio. It was basically finding patterns in the
audio and transforming these into equations. Interesting stuff.

------
Schwolop
What a remarkably easy to read article.

------
Snapps
Captivating title...


2019, Photo by ZINYANGE AUNTONY / AFP

But the regional drought saw certain sections of the famous falls dry-up over the summer. Facing a catastrophe, recent flooding in Zambia had an inadvertently positive affect on the iconic feature – water has now gushed towards the jewel in Africa’s crown, causing beautiful scenes like these:

Watch water flowing over Victoria Falls here:

Victoria Falls has water again after the earth took some space from us. pic.twitter.com/uPMnv95Yob — zambian kadollie 🎀 (@_QueenEnjay) April 1, 2020

The Mosi-Oa-Tunya/Victoria Falls WHS. Modeling in its own unique style that man can not comprehend pic.twitter.com/lMxMMQGhvb — thumbikani (@thumbikani) April 2, 2020

Africa my home. Victoria Falls back to life. Nature reigning supreme. "No one dare challenge when I say I am An African" Africa will survive. 🌹🌹🌹🌹🌹 pic.twitter.com/XtC6JfFt8S —Sophie Mokoena (@Sophie_Mokoena) April 1, 2020

Superb improvements across the board

The Zambezi River Authority have released a statement this week, explaining the epic improvements seen by Victoria Falls. The levels haven’t just got back on track, but they’re now way above the seasonal average:


debugging programs, however, must be operated manually, with engineers navigating through a large number of processes.

“Debuggers have worked well for sequential applications,” Bagchi said. “But when we extend these to large parallel applications, application developers are not very happy because it’s very time consuming and difficult to do the manual debugging. It is just difficult for human cognitive abilities to keep track of what is going on simultaneously in many processes and determine what is anomalous.”

So, to enable the automatic debugging of the simulations, the researchers created AutomaDeD, which stands for automata-based debugging for dissimilar parallel tasks.

“The idea is to use AutomaDeD as the simulation is running to automatically monitor what’s happening,” Bagchi said. “If things start going wrong, AutomaDeD would stop and flag which process and whichmoment satisfies $$\begin{aligned}
&\ \ \ \ \ \overline{V_{nn^\prime}^{II^\prime}(r)V_{n^{\prime\prime}n^{\prime\prime\prime}}^{I^{\prime\prime}I^{\prime\prime\prime}}(r^\prime)} \nonumber \\
&=  \left\{\delta_{nn^{\prime\prime}}\delta_{n^{\prime}n^{\prime\prime\prime}}
          \delta_{II^{\prime\prime}}\delta_{I^{\prime}I^{\prime\prime\prime}}
   + \delta_{nn^{\prime\prime\prime}}\delta_{n^{\prime}{n^{\prime\prime}}}
                      \delta_{II^{\prime\prime\prime}}\delta_{I^{\prime}{I^{\prime\prime}}}
   \right\} \nonumber
  \\ &\ \ \ \ \times  \sqrt{(2I+1)(2I^\prime+1)}  \nonumber
  \sum_{\lambda}
   \left(
     \begin{array}{ccc}
       I & \lambda & I^{\prime} \\
       0 & 0 & 0
     \end{array}
   \right)^{2} \nonumber\\
&\ \ \ \ \times
\alpha_{\lambda}(n,n^\prime;I,I^\prime;r, r^\prime).\end{aligned}$$ Here, the bars denote an ensemble average. $I$ is the spin of the intrinsic state labeled by


introduced to map quasi-elastic cross sections at $\theta_{\rm c.m.}$ to their notional values at $\theta_{\rm c.m.}=\pi$, by correcting for the centrifugal energy of the corresponding classical Rutherford trajectory [@timmers; @HR04]. In both figures, the dots represent experimental data taken at $\theta_{\rm lab} = 150^\circ$ [@piasecki], while the dashed lines show the results that take account of only the collective excitations. The solid lines represent the results that take into account the non-collective excitations in addition to the collective ones. To this end, we include non-collective states up to 5.7 MeV; this corresponds to 38 levels in $^{90}$Zr and 75 levels in $^{92}$Zr. We have confirmed that the results do not change significantly if the non-collective states are truncated at higher excitation energies. Note that these results have been obtained with abetween the two quasi-elastic barrier distributions. In this paper, we have employed the random-matrix model to generate appropriate couplings to non-collective states, enabling us to include these excitations in our coupled-channels calculations.

The results indicate that these excitations fill in the dip between the two main peaks in the barrier distribution for the $^{20}$Ne + $^{92}$Zr system, considerably smearing its peak structure. In contrast, the effect is much smaller for $^{20}$Ne + $^{90}$Zr, and the peak structure is not greatly affected by the inclusion of the non-collective excitations. The difference arises solely from the different level densities in these Zr isotopes. That is, the number of low-lying, non-collective states is much larger in $^{92}$Zr than in $^{90}$Zr. In both systems, the agreement with the experimental data for the quasi-elastic


this is essential for low-energy heavy-ion reactions. An interesting future problem would be to develop a more quantum mechanical approach for the deep-inelastic processes, still based on the random-matrix model.

We thank E. Piasecki for useful discussions. This work was supported by the Global COE Program “Weaving Science Web beyond Particle-Matter Hierarchy” at Tohoku University, and by the Japanese Ministry of Education, Culture, Sports, Science and Technology by Grant-in-Aid for Scientific Research under the program number (C) 22540262.

[99]{}

C.H. Dasso, S. Landowne, and A. Winther, Nucl. Phys. [**A405**]{}, 381 (1983); [**A407**]{}, 221 (1983).

M. Dasgupta, D.J. Hinde, N. Rowley, and A.M. Stefanini, Annu. Rev. Nucl. Part. Sci. [**48**]{}, 401(1998).

A. B. Balantekin and N. Takigawa, Rev. Mod. Phys. [**70**]{}, 77(1998).

K. Hagino and N. Takigawa, Prog. Theor. Phys. [**128**]{}, 1061 (2012).

N. Rowley, G.R.so demons would be more his thing.P: Then, as now, I am a little obsessional about the dark things of the night. The story was about a ninja with a magical sword, who had to travel into the underworld to reclaim the jewel that should be on the hilt of the sword, fighting demons along the way. It was, as you might imagine, awful…

Which Doctor Who episode left Paul breathless and wishing he could have written something that good?
J: Blink. Definitely Blink. It left me behind the sofa!P: Stephen Moffat’s incredible standalone episode Blink. One of the genuinely terrifying episodes of the new Doctor Who series, and still in my opinion the best.

Julia is a lecturer, gardener, PhD student, and long-suffering wife of a writer. She lives in


the West of London with one writer, 100 plants, and soon to be two leopard geckos

what a wonderful insight into Pauls world. Thank you both for being honest and so upfront about things. I am now convinced that Paul is every bit as charming in ‘real life’ as he comes across as through his writing.1. Field of the Invention
The present invention relates to a display apparatus for displaying an image on a display surface in which light guide elements are arranged in parallel with each other.
2. Description of the Related Art
In recent years, a liquid crystal display, plasma display, and various display devices have been developed as a display module for a display apparatus. The demand for these display devices is now increasing concomitantly with the start of the terrestrial digital media broadcasting, and the popularization of the Internet and cellular phone. Further, as for these displays, development of a large-sized display corresponding to a large-screen TV is demanded in addition to a small-sized display to be mounted on a mobile device, and the demand for the large-screen display is also increasing.
In


the conventional display, matrix wiring is provided on a glass substrate and, particularly in the liquid crystal display, a thin film transistor is provided at an intersection point of the matrix wiring. In the thin film processing, a semiconductor manufacturing process is used. Accordingly, in order to meet the demand for upsizing of the display, a large-sized equipment capable of performing a semiconductor manufacturing process on a large glass substrate is required, and hence a problem is caused that the amount of investment in the production line becomes enormous. Further, in the formation of the matrix wiring based on the thin film process, the wiring resistance becomes large concomitantly with the upsizing, and thus in a large-screen display, a signal delay resulting from the wiring resistance becomes agovernment told the court it was “not relying on any other recordings, of any person, for purposes of establishing the defendant’s guilt or determining his sentence, nor are there any other recordings that are part of the sentencing record,” Sullivan’s standing order required the special counsel to provide Flynn any information material to his guilt or sentence, and to present the court any information that might be favorable to Flynn that the government did not believe to be material.

Flynn’s prior attorneys may not have attempted to enforce the court’s order, given their penchant for pleasing the special counsel—possibly at a cost to their client—but from Powell’s preliminary comments during Monday’s hearing suggest she has every intent of demanding the documents. And that’s where things will get interesting.


tumors than in HR-positive (HR+) tumors. Moreover, the lowest pCR rate was found among patients with luminal A type tumors (6.4%), higher rate in luminal B type tumors (11%--22%), and a maximal pCR rate was observed in the groups of HER2+ and TN patients (27%--32%). In luminal B type, HER2+ and TN tumors patients with pCR had significantly higher OS compared to other subtypes. These observations were also confirmed by the previously mentioned meta-analyses \[[@B5][@B6]\].

The TN breast cancer (TNBC) subgroup can be divided into smaller subgroups on the basis of genetic differences \[[@B10]\]. Gene expression analysis of 386 tumor samples has revealed 6 distinct subtypes of TNBC: two basal-like (BL1 and BL2), an immuno-modulatory (IM), a mesenchymal (M), a mesenchymal stem-like (MSL), and a luminal androgen receptor (LAR)general, results proved the superiority of response-guided (8×TAC or TAC-NX) chemotherapy \[[@B35]\].

Response-guided therapy was also applied in the GEPARQUINTO trial. Patients with HER2− tumors were firstly randomized to receive four cycles of epirubicin-cyclophosphamide with or without bevacizumab. Then, four cycles of docetaxel with or without bevacizumab were administered to patients with clinical response, while nonresponders received weekly paclitaxel 12 with or without everolimus. Although this study design did not allow the assessment of the benefit of the response-guided therapy, the application of this therapy as a recognized therapeutic approach, could be concluded from this trial setting \[[@B36]\].

In a trial conducted by Wang-Lopez et al. \[[@B37]\], a number of 264 previously untreated stage II--III operable patients with breast cancer were randomized to three cycles of 5-fluorouracil-epirubicin-cyclophosphamide combination (FEC), followed


and CT scan for neck and chest (R)•Positron emission tomography combined with computed tomography scanning is recommended for the assessment of response after chemoradiotherapy, and has a role in assessing recurrence (R)•Examination under anaesthetic is strongly recommended, but not mandatory (R)

Pre-treatment staging {#sec3-4}
---------------------

Pre-treatment staging for the primary tumour based on the tumour--node--metastasis classification (7th edition) for oropharyngeal tumours is shown in [Box I](#box1){ref-type="boxed-text"}. BOX ITNM STAGING FOR OROPHARYNGEAL SQUAMOUS CELL CARCINOMA•TX: Primary tumour cannot be assessed•T0: No evidence of primary tumour•Tis: Carcinoma in situ•T1: Tumour 2 cm or less in greatest dimension•T2: Tumour larger than 2 cm but 4 cm or less in greatest dimension•T3: Tumour larger than 4 cm in greatest dimension or extension to lingual surface of epiglottis•T4a: Tumour invades the larynx, deep/extrinsic muscle of tongue, medial pterygoid, hard palatethe future, potentially on selection of treatment modality. There are several ongoing or planned clinical trials for HPV-positive and HPV-negative OPSCC and recruitment into clinical trials addressing these issues is highly recommended. Development of biomarker classifiers for treatment selection is also high recommended.

Recommendations•Advanced oropharyngeal carcinoma can be treated with primary chemoradiotherapy or transoral surgery and adjuvant (chemo)radiotherapy (R)•The N0 neck should be treated electively -- either by radiotherapy or selective neck dissection (R)•Patients with advanced nodal (N2 or N3) disease receiving radical chemoradiotherapy should have a PET-CT scan 10--12 weeks after treatment, with a subsequent neck dissection within 4 weeks if residual abnormal or equivocal nodal disease is detected (R)•Intensity modulated radiotherapy reduces toxicity in patients treated with radical radiotherapy, compared with conventional radiotherapy (R)•Post-operative chemoradiotherapy is currently


(b), which provides that when two competing
presumptions for paternity exists the presumption upon “which on the facts is founded on
the weightier considerations of policy and logic controls.”
       S.T. filed a declaration asserting that she was cohabitating with Martin at the time
daughter was conceived. She also filed a brief claiming the marital presumption of
paternity under section 7540 has precedence over the presumption set forth under
section 7611.
   3. The Hearing and Trial
       On October 21, 2014, the trial court held a hearing and found there was a
conclusive presumption that Martin was daughter’s father, because he was married to and
cohabitating with S.T. when daughter was conceived pursuant to section 7540.
Thereafter, it found Martin was a necessary partyconstitute receiving a child into a home. In its statement of decision,
the trial court expressed the view that receiving daughter into his home required W.S. to
prove regular visitation and the assumption of parent-type obligations and duties such as
feeding, bathing, putting daughter to bed, changing her clothes, disciplining her, and
other similar tasks. W.S. argues section 7611, subdivision (d) only required him to
physically take daughter inside his home, and the trial court’s additional requirements
were superfluous and not within the meaning of the statute. As we explain below, we
reject W.S.’s claim.
       a. Overview and Standard of Review
       W.S. questions the trial court’s interpretation of section 7611, subdivision (d).
The interpretation of a statute is a question of law, which we


S. (1992) 1 Cal.4th 816, 824 (Kelsey S.).) A father is not elevated to presumed
father status unless he has demonstrated a “commitment to the child and the child’s
welfare . . . regardless of whether he is biologically the father.” (T.R., supra, at p. 1212.)
       Section 7611 sets forth several rebuttable presumptions of paternity. “ ‘The
statutory purpose [of section 7611] is to distinguish between those fathers who have
entered into some familial relationship with the mother and child and those who have
not.’ ” (T.R., supra, 132 Cal.App.4th at p. 1209.) Section 7611, subdivision (d) creates a
rebuttable presumption of presumed fatherhood if “[t]he presumed parent receives the
child into his or her home and openly holds out the child as his or her natural child.”
 the alleged father’s home is, by itself,
insufficient under section 7611, subdivision (d).
       In Kelsey S., our Supreme Court acknowledged that historically under cases like
Richard M., there was a liberal interpretation of the receiving requirement, and even
constructive receipt was potentially sufficient. (Kelsey S., supra, 1 Cal.4th at p. 828.)
However, cases pre-dating the UPA like Richard M. were decided in a much different
statutory context. When Richard M. was decided, “the determination was whether the
child had been legitimated by the father.” (Ibid., italics added.) There was stigma and
unfavorable legal treatment attached to a classification of a child as illegitimate. (Ibid.)
An illegitimate child had no legal father. In contrast, after the enactment of the UPA and
the replacement of the concept of legitimacy with parentage, children will


Cal.App.4th 1361,
1369 (Cheyenne B.). In Cheyenne B., the father was incarcerated when the child was
born and sporadically visited her several times. (Ibid.) Sometimes he would meet her at
a local Wal-Mart when he drove through the town where she lived. (Ibid.) The appellate
court concluded substantial evidence supported the trial court’s determination that the

                                               15
father’s visits with the child were too inconsistent and irregular to satisfy the requirement
that he received the child into his home. (Id. at p. 1380.)
     parent status entitles
one to services not available to a natural parent who has not attained that status.
However, it would make little sense to apply one definition of “receiving” as used in
section 7611 to dependency actions while applying another definition to all other
proceedings. Section 7611 should be subject to only one interpretation, regardless of the
type of action in which it is used.
       W.S. also argues the trial court impermissibly evaluated him using the factors set
forth in Kelsey S., supra, 1 Cal.4th 816. Under Kelsey S., certain fathers may acquire the
rights of a presumed father without meeting the requirements of any of the statutory
presumptions, including the presumption set forth under section 7611. Under Kelsey S.,
“ ‘an unwed biological father who comes forward at the


fact that daughter has been inside his home. Thus, the
trial court correctly considered whether W.S. assumed parental responsibilities and took
on the role of a parent in daughter’s life. 7
   2. Visitation Rights
       Next, W.S. argues that as daughter’s biological father, he has a right to visitation
under section 3100. He insists the provision regarding visitation found in section 3100
operates notwithstanding his failure to achieve status as a presumed parent.
Alternatively, he claims that even if he was not a presumed parent, the court had the
discretion to grant visitation rights to nonparents, and it failed to exercise this discretion.
       First, we find that section 3100 is inapplicable in the context of this case.
Section 3100, subdivision (a) begins      Second, W.S.’s argument that section 3100’s provision providing for parental
visitation applies to him fails as a matter of law. W.S. argues that a “parent” under
section 3100 is not limited to presumptive parents as defined under the UPA. W.S.’s
claim is a question of law that we review de novo. (People ex rel. Lockyer v. Shamrock
Foods Co., supra, 24 Cal.4th at p. 432.)
       “Division 8, part 2 of the Family Code governs the right to custody of a minor
child. Part 2 applies not only to dissolution, nullity and legal separation proceedings and
actions for exclusive custody, but also to proceedings to determine custody or visitation
in actions brought under the . . . UPA. (§ 3021, added by Stats. 1993,


   Preliminarily, we find W.S.’s constitutional arguments are waived for failure to
raise them to the trial court. “ ‘ “Typically, constitutional issues not raised in earlier civil
proceedings are waived on appeal.” ’ ” (Neil S. v. Mary L. (2011) 199 Cal.App.4th 240,
254 (Neil S.).) W.S. did not discuss these constitutional issues in either his trial brief or
his original petition to establish a parental relationship.
       Furthermore, even if we were to consider W.S.’s arguments as pure questions of
law presented by undisputed facts, we would reject them. First, we find Kelsey S., supra,
1 Cal.4th 816 instructive on whether W.S. had a protected liberty interest in establishing
a parental relationship with daughter and whether his rights were entitled to equal
protection as to a mother’sLegislative classification is permissible when made for a
lawful state purpose and when the classification bears a rational relationship to that
       8
        We briefly discussed the Kelsey S. factors earlier in our opinion, when we
evaluated W.S.’s claim that he qualified as a presumed parent under section 7611.

                                             22
purpose. [Citations.] ‘Wide discretion is vested in the Legislature in making the
classification and every presumption is in favor of the validity of the statute; the


Q:

Python: Up-Vector math for Curve

I've been working on python Curve Deformation tool. I need some help with the math. Possibly someone can help here. I cannot find correct UpVec for my custom curve.
Here are the screens which explain the problem:

Here is my tool in action:
https://youtu.be/Nxu6-0xm3Io
Here is the code I did but it's buggy in some angles. It inverts to 180 degrees on some angles:
https://github.com/mifth/mifthtools/blob/96e73eb3a2613b3f1396ddd7c4bdd9d0419ca5e3/blender/addons/mira_tools/mi_curve_guide.py#L515-L537
All I do is just cross direction of the point to global X and Y axis. Any help will be appreciated to get the quality of upVec as in Blender Curves.
And you can get the tool here:
https://github.com/mifth/mifthtools
http://blenderartists.org/forum/showthread.php?366107-MiraTools
Thanks.

A:

There are 3 ways for upVec to be found:
2 and 3 versions were suggested by mano-wii from here http://blenderartists.org/forum/showthread.php?361154-Coordinates-of-resolution-points-of-a-Bezier-Curve
1) Cross vec. https://github.com/mifth/mifthtools/blob/6b0469faea18d3375c3f3257963d7c85f327c44c/blender/addons/mira_tools/mi_curve_guide.py#L486-L488
2) Project vec.
http://blenderartists.org/forum/showthread.php?361154-Coordinates-of-resolution-points-of-a-Bezier-Curve&p=2866256&viewfull=1#post2866256
https://github.com/mifth/mifthtools/blob/6b0469faea18d3375c3f3257963d7c85f327c44c/blender/addons/mira_tools/mi_curve_guide.py#L490-L492
3) Dot vec.
http://blenderartists.org/forum/showthread.php?361154-Coordinates-of-resolution-points-of-a-Bezier-Curve&p=2866427&viewfull=1#post2866427
https://github.com/mifth/mifthtools/blob/6b0469faea18d3375c3f3257963d7c85f327c44c/blender/addons/mira_tools/mi_curve_guide.py#L494-L497
I choosed Crosscurrent densities increase and the structural size of electronics (e.g., the width of conductors in ICs) decrease.
Electromigration damage may be cumulative in that the migration of ions may contribute over time to cause an open circuit (due to voids forming from ion migration) or a short circuit (due to hillocks formed by ion accumulation). A failure of even a single conductor may cause an IC to malfunction. If the malfunction occurs before an end of a stipulated lifetime of the IC, expensive recalls or loss of market share may result.


This is not a UNHCR publication. UNHCR is not responsible for, nor does it necessarily endorse, its content. Any views expressed are solely those of the author or publisher and do not necessarily reflect those of UNHCR, the United Nations or its Member States.

In the middle of the salt-water Lake Budi, seven metres below sea level, remote Nahuelhuapi Island is home to a Mapuche community. The island is located in Cautín province, in the Saavedra district of the Araucanía region, in southern Chile.

At first sight, it might seem as though the inhabitants of Nahuelhuapi live in paradise, surrounded by great natural beauty. However, the 11 families living on the island face daily difficulties as a result of the remoteness and the climate. The fact that it is ansuch liability only springs from known dangers in specific geographic locations. (DE # 11 at 3); Carlisle, 475 So.2d at 251. Moreover, Defendant states that imposing heightened duties beyond a duty to warn is inappropriate.
Upon review of Plaintiffs' allegations and in light of the pertinent case law cited by the parties, the Court agrees with Defendant and finds that Plaintiffs have failed to state a cause of action for negligence. Carlisle and its progeny merely state that a cruise ship may be liable for a failure to warn of known dangers in known settings. See Carlisle, 475 So.2d at 251 ("[T]he duty to warn is limited to dangers known to exist in the particular place where the passenger is invited to, or reasonably *1220 may be expected to


visit.") (emphasis added). Permitting Plaintiffs to proceed on their claim of negligence against Defendant solely because of a rising crime rate in Nassau would improperly expand a cruise line's duties to its customers. Here, there are no allegations in either of the Complaints that RCL knew or should have known of dangerous conditions on either the Caribbean Segway Tour or on the grounds of Earth Village Nature Preserve. Instead, the only allegations pertain to "actual knowledge of crimes against tourists in Nassau, as a group of passengers on a Defendant-sponsored Nassau excursion were robbed at gunpoint approximately one month prior to the subject incident." (DE # 1 ¶ 21). Such allegations are insufficient to trigger a duty under Carlisle. And since without duty there can be no breach,be dismissed with leave to amend. Upon amendment, Plaintiffs are instructed to state with clarity the basis for any negligence action against Defendant, and to plead individually such separate claims as negligence and negligent retention.

ii. Count Two: Misleading Advertising
In support of their claim for Misleading Advertising under Count II of their respective Complaints, Plaintiffs allege that Defendant's failure to notify them of the "exploding crime rate in Nassau" constitutes misleading advertisement insomuch as Defendant's omission affected their decision to purchase the shore excursion. Plaintiffs cite certain language found under the FAQ section of Defendant's website in support of her claim, as well as the actions of Defendant's employees, which Plaintiffs states made them believe the tour was safe and fun.
To prove misleading advertising under Florida law, which is


was installed by John Compton of London, although it did not gain its impressive case (designed by Sebastian Comper) until 1963. It is played from a four manual console in the Consistory Court area of the Cathedral.  This was overhauled in 1992. In 1973, an additional instrument was installed in the new retro-choir (east end) by Cousans of Lincoln.

Organists
Between April 2013 and December 2014, Canon Peter Gould undertook a musical pilgrimage of 270 churches, in which he raised £7,478.78 over 39 tour days, performing to a collective audience of over 3,500 people. During the tour three church organs were found to be in a poor state.

On 4 January 2015, Canon Peter Gould resigned as Director of Music and was succeeded by Hugh Morris who had originally workedsupport the product.
People should each have their own guidelines for
testing and reviewing release candidates, and what
factors that they consider will impact their vote.
Mostly it is common-sense stuff, but if you need
help then see:
http://www.apache.org/dev/#releases
-David


// Copyright 2012 Google Inc. All Rights Reserved.
//
// Use of this source code is governed by a BSD-style license
// that can be found in the COPYING file in the root of the source
// tree. An additional intellectual property rights grant can be found
// in the file PATENTS. All contributing project authors may
// be found in the AUTHORS file in the root of the source tree.
// -----------------------------------------------------------------------------
//
// Rescaling functions
//
// Author: Skal (pascal.massimino@gmail.com)

#ifndef WEBP_UTILS_RESCALER_UTILS_H_
#define WEBP_UTILS_RESCALER_UTILS_H_

#ifdef __cplusplus
extern "C" {
#endif

#include "src/webp/types.h"

#define WEBP_RESCALER_RFIX 32   // fixed-point precision for multiplies
#define WEBP_RESCALER_ONE (1ull << WEBP_RESCALER_RFIX)
#define WEBP_RESCALER_FRAC(x, y) \
    ((uint32_t)(((uint64_t)(x) << WEBP_RESCALER_RFIX) / (y)))

// Structure used for on-the-fly rescaling
typedef uint32_t rescaler_t;   // type for side-buffer
typedef struct WebPRescaler WebPRescaler;
struct WebPRescaler {
  int x_expand;      5.010001;
use strict;
use warnings;

use Test::More tests => 17;

use lib 'inc';
use Marpa::R2::Test;
use Marpa::R2;

## no critic (Subroutines::RequireArgUnpacking)

sub generate_action {
    my ($lhs) = @_;
    return sub {
        shift;
        my $v_count = scalar @_;
        return q{-} if $v_count <= 0;
        my @vals = map { $_ // q{-} } @_;
        return $lhs . '(' . ( join q{;}, @vals ) . ')';
        }
} ## end sub generate_action

my $C_action       = generate_action('C');
my $S_action       = generate_action('S');
my


dissertation entitled Hyper-Calvinism and John Gill. He defined the phenomenon as: . . . "that school of supralapsarian Five Point Calvinism which so stresses the sovereignty of God by overemphasizing the secret over the revealed will and eternity over time, that it minimizes the responsibility of Man, notably with respect to the denial of the word â€˜offer' in relation to the preaching of the Gospel of a finished and limited atonement, thus undermining the universal duty of sinners to believe savingly with assurance that the Lord Jesus Christ died for them." 5

This definition contains some valid aspects, but Daniel goes on to finally reduce it to one factor: "it is the rejection of the word offer in connection with evangelism for supposedly Calvinistic reasons . . . thedesire

8.1. Anger, fear and shame shut down sexual desire

8.2. Multigenerational injuries in women cause women to shut down sexually

8.2.1. Spirits encourage women to shut down their sexual desire

8.3. Being shut down indicates a state of anger

8.4. Working through emotions to unblock sexual desire in a relationship

8.4.1. Method 1: Feeling emotions in a sexual situation

8.4.2. Method 2: Noticing emotional issues on a day-to-day basis

8.5. Working through spirit influence causing women to be sexually shut down

8.5.1. An example of a woman who needs to address her emotions about women spirits before dealing with inter-gender issues

9. Finding our ideal partner

9.1. An example of a woman looking for her ideal partner

9.2. Examining our expectations of and preferences for our ideal partner

9.3. An instance of spirits shutting down audience members

9.3.1. The benefits of


the differences in the quality of love between the soul when they're incarnated to the quality of love that you guys have. Is it just quantity of love that you receive, or is it that your soul grows in a way that is different?

Well no, because before you can reincarnate you've got to go through union. To go through the union you've got to receive quite a lot of Divine Love, which is very, very different to natural love. The reality is that there will be different qualities. He will see that our spirit body, for instance, does look quite different, even though he can see the injuries in my stomach and he can see the injury across my chest, a bit on my shoulder, and a bitall those questions as we proceed. Also, when we pass into the spirit world we still have the same groups of emotional injuries that drove sexual attraction on Earth, and for that reason many spirits who pass into the first to third spheres in the spirit world, they still believe they have attractions in a certain direction, and many times they only discover that they don't once they hit the condition of love with the fourth and fifth dimensional spaces in the spirit world. Many of them before then don't really understand why those attractions exist, and what we want to do today is explain why those attractions exist. [00:49:38.10]

3.2. The withered state of souls prevents awareness

Participant: With the prune of a soul, does that explain why we


things that create attraction between soulmates

There are three primary things that we need to focus on with the attraction between the two halves of the soul. These primary things you already know about actually. That's a blessing, that you already know them.

5.1. Truth

The first thing that causes a huge sexual attraction between the two halves of the soul is truth. Even when only one half of these two halves get into a condition where they begin facing their truth, and I'm not talking about intellectual truth here, I'm talking about actually feeling the truth about things, all of a sudden the other half, no matter what its condition, will be sexually attracted to that half. When I say sexually attracted, it will feel a draw and a desireseeing the linkage.

Myself and Mary, we often meet people who are in different relationships, or not in relationships at all, and we go, "Yeah those two are soulmates," but we don't tell them, we just let them work through the emotions that they need to work through before they become aware of it themselves. Because you can actually feel the character or nature of each person's soul once you become emotionally open to doing that, and you can feel the differences in the character and nature of each person's soul. When two people feel identical in their nature, even though they may be in a different form physically, one might be in a male body and another one in a female body, you go, "Whoa! These are probably


how joining or attraction occurs between the two halves of the soul if they're in a state of perfection. We've also talked about how the truth, desires and love are the things to activate within yourself, whether you're in error or not, if you want to draw your soulmate to you. But we've yet to discuss sexual attraction. We've discussed these principles but we've yet to discuss sexual attraction. We now need to put sexual attraction together with these other principles.

6. Sexual attraction is created by energy flow between chakras

Mary: We were going to talk about sexy feelings and chakra openings.

6.1. Chakras are energy systems of our body

Many of us are aware that in our first incarnation in particular we have seven primary chakra points. Chakras are energyWhat are they? What are the main reasons why a person wouldn't feel desire? There's two main reasons.

Mary: Can you think of any Eva?

Participant: Fear.

Fear is the primary one, and anger is another. And of course there's another that's probably fairly dominant as well, which is...

Mary: Shame.

Shame, which is the result of judgement, if you like. Now, those things in particular affect desire.

Fear, anger and shame suppress desire

If you don't feel sexual desire, then something's going on with one of these three things.

Participant: Or all three of them?

Or all three of them, yes. When it comes to healing emotions revolving around the other gender in particular, in terms of attractions, we need to be particularly focused upon the feelings we have with the other gender. If you're with


like that. So it was a lot about I didn't want to take up the space here; kind of not being important enough or being wrong for some reason.

Yes, see I suggest actually that the real reason, Eva, is that there are women spirits with you who do not want you to heal your sexual desire.

Participant: I actually guessed about that but I'm not so aware of spirits.

8.2.1. Spirits encourage women to shut down their sexual desire

And this is happening with many women at the moment. There are many, many women spirits in the spirit world who are enraged by the entire concept of the soulmate union. In other words, they feel the soulmate union is definitely not where women want to go. They want women to haveneed to feel special. My mother and my father had put me on a pedestal. They still do. So I am gorgeous. Of course I know I'm not.

You don't feel it.

Participant: No because I don't want to sit up there on the pedestal. And so I realise this is something I need to have from both, I guess, men and women; I am special. And the last thing I got that I also feel that about the partner, or my friends, or everyone I sort of choose, that they need to be special too. And that's also a big burden.

To make me feel more special.

Participant: To make me more special.

Yeah. It's a bit like if you have emotional injury that you're not worldly enough, then you'll want a


that then causes me to feel ashamed about my own. [00:06:31.04]

Participant: Right.

Mary: That's where the conflict comes from. For example, if you came up to me now and said, "You're a dirty cow because you're sleeping with this man and you're not married," I'd go, "I feel pretty dirty about a lot of things but that's not one of them," because I'm not invested in what you think about me.

But if you said that Mary was dirty because of something she did in the first century...

Mary: Or even in this life...

Or even in this life, she would feel quite different. The principle here is that we take on the opinions of others based on what is already unhealed within ourselves. But belief systems certainly have a large effectWhy would I be attracted to celibacy? What emotions would cause me to be attracted to celibacy as a way of life?

Participant: Denial. It feels like denial.

Denial of what?

Participant: Of my feelings. Denial of myself. Denial of my urges.

Denial of sexual desire.

Participant: Yes.

Mary: Shame might cause me to deny my sexual desire. What else might cause me?

Participant: Just feeling uncomfortable with it that makes me want to not deal with sex at all, and being focused on being holy and...

Not wanting to deal with any sexual desires through...

Participant: Because I don't want to be sinful.

Okay. A definition of sinfulness. As a result of that I feel that celibacy is my course of action. Anything else? I can think of quite a lot more actually.

Mary: A fear of emotional


sexual practices. My suggestion instead of doing that is to start questioning whether love is involved in any sexual interaction. You see, a soulmate couple that has unhealed emotions can certainly still engage in unhealed sexual practices. You can be in a relationship with your soulmate and still have sexual practices that need to be healed. Do you follow me? And the key is to allow yourself to feel the lack of love in these things.

11.5. All sexual injuries need to be healed to become at-one with God

Now if you have a desire for God, you will always eventually progress towards God, and anything that causes you to stagnate in your progress towards God obviously needs to be healed. Sexual practices can certainly cause your stagnation in yourend of the day will prevent your at-onement with God as much as a practice of celibacy will. That's the irony.

Mary: Is it as much as?

Yeah! Well it is at one point sooner or later; if I continue practicing celibacy at one point I'm going to stagnate in my condition, and from that moment on I am never going to become at one with God. That condition might be a bit higher than when I have practiced S&M bondage, but at the end of the day they're still stagnant conditions. So they're just as bad as each other preventing us from becoming at one with God. If we're looking at our desire to become at-one with God and at one with our soulmate, both practices will never, never


we need to be open to seeing the desire and then addressing it and talking about it openly without condemnation and judgement because as soon as we judge the person, as soon as we condemn the person, from that moment on they are unable to heal the emotion. From that moment on they are going to hold onto the emotion and deny it. They'll even try to make out they don't have it when they still have it. And that's not going to get us anywhere when it comes to healing that sexually. [01:22:11.29]

12.1. Children are open to sexual abuse due to unhealed emotions in their parents

Mary: But in answer to your question, children don't have a Law of Attraction. It's based on their parents' Law of Attractionand also it's based on the harm that individual is causing to children. They hold the ultimate responsibility for that and then there are unhealed emotions within both parents that cause the lack of protection if you like for that child, for them then to be harmed.

Many parents can't even recognise when their child has been sexually harmed just once. And the reason why they can't recognise it is that they themselves have emotional injuries that prevent the recognition of such harm. The truth is that when parents are totally open emotionally and totally open sexually they would instantly recognise the danger even before it occurred. They'd recognise the type of person who would be involved in some kind of act of incest, and they would instantly take


look very nice but the victims are speaking openly about what happened to them. I thought it is maybe a way to heal what is there, underlying in the whole society.

Definitely. The truth is the always the thing that leads to healing. The truth of what actually happened is always what leads to healing. Having victims who have had incest able to speak openly and frankly about what's happened to them is a very powerful form of healing for them. They've got to be very careful though that they don't get into the cycle of just talking about what's happened without feeling the actual underlying emotions about what happened. That's the thing they need to take care of. However on the priest side, while the church still protectsherself acting in a couple of different ways as a result. She may then feel very attracted to daddy because daddy's giving her feelings that she doesn't recognise and cannot separate as feelings that should be only going to her soulmate, and as a result of that she starts feeling feelings for her dad that she doesn't understand. And that causes a distortion in all of her subsequent sexual relationships. Just the feeling of sexual attraction coming from a parent towards a child or an adult towards a child is automatically disturbing for the child if the child is open and unprotected from that feeling. [01:58:19.11]

Participant: Can we say that any extra special attention, besides your soulmate or your partner, to anyone is a sexual...

Well let's raise this


the woman to have.

Mary: Yes.

What he expects from the woman. He is now no longer expecting it from his wife or partner, but now he's expecting it from his daughter. This automatically creates a distortion in his relationship with his daughter. It also creates a distortion in her. She is now going to have an undue connection with her father that normally she would be giving to her soulmate, to somebody else instead. So now there's a tie.

This man might have an expectation of his wife that she does other things, for example that she likes his body. He might parade around naked in front of his wife, wanting his wife to like his body, and his wife doesn't like his body. So he continues to parade aroundin the sense of where sexual incest has actually occurred. But there are sexual injuries that cause the man to not deal with the issue with his partner, and causes them instead to seek the same emotions from his daughter. [02:04:30.12]

Mary: And then it actually creates a great deal of sexual injury in the daughter.

In the daughter. She will then act upon these injuries with other males as a result of the injuries that have been created in her.

Participant: Yes. It's like a soul-based sexual energy exchange.

Yes, well, he might actually feel that she should be asexual. He might project, "A good woman doesn't have sex with anybody." He might project that at her. And she says, "No worries, daddy, a good woman doesn't have sex with anybody.


any co-dependent addictions within you - provided you both have a desire for God. But if you don't have a desire for God and you only have a desire for each other and you feel quite happy with this dynamic of "I do things for you, you do things for me" going on for the rest of your life, then you'll probably stay the rest of your life in that relationship and feel quite content about the relationship. But that is not a soulmate relationship. That's only two people getting what they want from each other. [02:15:11.16]

Mary: And eventually the process of barter, which is essentially what's happening there, can get very tiring and taxing and anger can start to build, and this is when sexual relationships startthe judgement. Her husband even threatened to kill her. I mean they went through hell but they stuck together. For years they had six kids, who they had to take on holiday and everything, financial downturn. They eventually got married. They're now married seven years and every time I go home I say, "Doris, was it worth it?" And if I see this couple together it's like I almost see stars between them. I don't judge them. It taught me a lot about not judging people. Had a guy done it we'd all say, you know, "Bastard! Typical!" [02:26:05.16]

Yeah, yeah. (Laughs)

Participant: This was a friend that I loved and it happened to her and I can just explain it with this soulmate theory because they've been through so


And can I just recommend another book that maybe some of you will be interested in?

And it will help you particularly with issues of abuse or things like that.

Mary: "The body never lies" by Alice Miller. That is just a powerful book. Alice Miller passed just recently. I think she was German; I think her work was actually originally in German but translated to English. She talks a lot about the truth about emotions, childhood and your body, trusting your body to tell you stories. [02:36:52.00]

Very good books, both of them. "The body never lies" is a bit more emotionally focused whereas "Are you the one for me" is a little bit more intellectually focused, but both are very, very good books. We'd like to recommend those toof that today with some of these questions that you might come up with.

17. Soul incarnation

Participant: Yesterday, if I understood correctly, you said that the soul splits into two and the two soulmates try to find each other. They come into the material world and are born into a physical body and a spiritual body.

That's correct.

Participant: Would that not imply that the soulmates are born on the same date?

No, it doesn't happen that way. I can explain how it happens in a bit more detail.

Remember that you've got the un-incarnated soul that is in its unified state. It's actually sitting in a place that's in the same place that you finish up at in the soul union state when you grow, and let's call that the 22nd dimension,


mean that their soulmate is Greek. They could be any of the countries nearby; it just depends on a whole lot of factors, particularly the attraction of the two parents that are having a sexual union.

The key is to not worry too much about that but use this technique that God has given us, and that is to open up our desires and passions, live in harmony with truth and love, and when you live in that state the attraction will automatically occur. What a lot of people find, which is very interesting, is that they've actually known their soulmate, and once they start activating those particular things, they start having feelings about one particular person in their past. Many people find that they have met their soulmatea person who's angry with them with the same amount of love as a person who likes them. They're in a state of consistent joy constantly and they're in a state of consistent peace internally. Constantly. They are also absorbing truths from the universe constantly, so they're constantly growing. They're like a child in constant experimentation with the universe. There's no resistance to learning.

Imagine for a moment instead of having, like most of us, deep resistances to learning new things, this child is now an adult that has the same kind of feeling as a child, and has no resistance to learning new things. No shut-down emotions, no feelings of resistance in them to changing or growing. Imagine this constant state of internal peace and wellbeing, knowing that