connection to the PCR assay. The results were analysed using the 2^−ΔΔCt^ method and are presented as the fold differences in the expression of each target gene compared to that of β-actin in the same sample. All the samples were processed in duplicate.

Western blot analysis {#Sec13}
---------------------

The HepG2 cells were harvested and lysed with ice-cold RIPA lysis buffer containing protease inhibitor cocktail (Roche Diagnostics, Mannheim, Germany). The protein concentration was determined using a Bio-Rad DC protein assay kit (Bio-Rad, Hercules, CA, USA) according to the manufacturer's instructions. Briefly, after boiling to achieve protein denaturation, equal amounts of total protein (40 µg) were loaded onto gels and resolved by 10% sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) for 2 h at room temperature. The proteins were subsequently transferred to polyvinylideneInc., Milpitas, CA, USA). The glycerol levels were measured by detecting the absorbance at 550 nm using an autoanalyser (Cobas-Mira; Roche Diagnostics, Basel, Switzerland) following the manufacturer's instructions. All the samples were measured in duplicate.

Statistical analyses {#Sec18}
--------------------

All the experimental data are presented as the means ± SEs. Statistical differences were evaluated by Student's *t*-test or one-way analysis of variance (ANOVA) as appropriate using SPSS 18.0 analysis software (SPSS, Chicago, IL, USA). The differences were considered significant at *P* \< 0.05.

Data availability statement {#Sec19}
---------------------------

All data are fully available without restriction.

Naiqian Zhao and Xiaoyan Li contributed equally to this work.

**Publisher\'s note:** Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This work was supported by grants from the Natural Science Foundation of Shanxi Province (2014011043-1) and the Social Development


// Distributed under the terms of the MIT license
// Test case submitted to project by https://github.com/practicalswift (practicalswift)
// Test case found by fuzzing

class i<m{init(l:m){{}class k{func m<l:m}->{{}{}{}class f{{}func h{{}func j{{}enum S{ASIO officers leaving Canberra on a secret mission to break some bad news. What ASIO's discovered will have far reaching consequences for both Australia and its allies. Such is the sensitivity of the information it can only be delivered by a face to face meeting. It seems that Chinese hackers, notorious for waging a virtual cyber war stealing secrets and spying have hit the bulls-eye. And even that's secret.

ALASTAIR MACGIBBON, DIRECTOR, CENTRE FOR INTERNET SAFETY: The question is how many successful events they've been? Most people who work in this space know of many ah but they won't tell you what they are because they can't divulge their sources.

ANDREW FOWLER: It's a secret war where the body count is climbing daily.

ANDREW JOHNSTONE-BURT, PUBLIC SECTOR LEADER, DELOITTE AUSTRALIA: There's


military products, have made the company a target. The ASIO investigation revealed that when a Codan executive visiting China logged in to the Wi-Fi at his hotel, the Chinese struck. They inserted malware onto the work laptop. From there it infected Codan's Australian computer system. Intelligence sources believe it was this malware which contained a piece of computer code designed to target files on the Codan system.

JOHN BLACKBURN: This comes back to where the problem is in cyber security in Australia. You can protect the crown jewels but if the case that's surrounding the crown jewels is made of glass it's a little bit fragile, then you've got a bit of a problem here.

ALASTAIR MACGIBBON: There but for the grace of God goes every other defence contractor orstart to identify vulnerabilities, then ah that sophisticated ah hackers could get to, then all of a sudden less sophisticated ones can start to find those vulnerabilities and weaknesses if you like...

ANDREW FOWLER: But if you don't talk about the vulnerabilities then...

DR GARY WATERS, STRATEGIC CONSULTANT: Then you can't talk about the solutions.

ANDREW FOWLER: The Australian Government and its intelligence agencies are facing off against a new, unseen enemy. It's a battle largely being fought out behind a veil of secrecy, a secret war which has already cost Australia billions of dollars.

ANDREW FOWLER: So this is Canberra, what makes it so unusual in the cyber world?

ALASTAIR MACGIBBON: Well I think it's fair to say that some of our allies are more open in talking about cyber matters than


working in the Defence complex in Canberra's Russell Hill sent a highly classified document from his desk computer to his home email account. Hackers had earlier targeted the officer's home computer with what's known as a spear phishing email in the guise of a interesting link. Once clicked, a virus loaded onto the computer. When the Defence dept document was opened, the virus fired a copy back to China.

INFORMANT II: I think the real problem that a nation state like China has is what to do with all the data, not how to get the data. Their attacks, their systems are so well developed and refined that I think the problem that presents to the people like the Chinese is what to do with all the data they'veWest.

RICHARD BEJTLICH: We estimate that there's ah, as far as the numbers of people who work there somewhere in the hundreds, potentially a thousand, the building that we identified is part of a compound, and we know that their expertise is English language speaking companies.

ANDREW FOWLER: His team traced the cyber attacks back to their source. The Mandiant report cited hits on more than 100 mainly US companies and for the first time named the attacker. The attacks come from the second bureau of the People's Liberation Army's General Staff Department Three, commonly known by its Military Unit Cover Designator as Unit 61398.

DES BALL: It's an entirely secretive organisation. Ah, what you can find out about it only comes about because of what mistakes they make. They do


overall building but also of the communications cabling and server locations, of the floor plans, and the security systems. It was more than theft. It reeked of a espionage operation, someone had mounted a cyber hit on a contractor involved in the site. The plans were traced to a server in China. We put our discovery to Professor Des Ball.

DES BALL: That's of major significance. Ah, it's to me only one element of the sorts of activities which the Chinese are up to these days.

ANDREW FOWLER: But why is it particularly significant that they are building plans?

DES BALL: Once you get those building plans you can start constructing your own wiring diagrams, where the linkages are through telephone connections, through Wi-Fi connections, which rooms are likely to beincidents are affecting the Australian businesses that form part of Australia's systems of national interest, including critical infrastructure... The findings from this survey provide a picture of the current cyber security measures these businesses have in place; the recent cyber incidents they have experienced; and their reporting of them.

The 2013 Data Breach Investigations Report | Verizon | 2013 - The annual Verizon report offers stats on the percentage of espionage-related attacks and security breaches on organisations around the world.

Strong and Secure: A Strategy for Australia's National Security | Australian Government | 23 Jan 2013 - The Strategy provides the overarching framework to guide Australia's national security efforts over the next five years.

The Cyber Crime and Security Survey Report | CERT | 2012 - The inaugural Survey was designed


Kokoda Papers | Feb 2011 - This paper focuses on the cyber security environment in the 2020 to 2030 timeframe, exploring the likely future cyber environment and the challenges, threats and vulnerabilities facing Australia and western societies in that timeframe. By John Blackburn and Dr Gary Waters. [PDF 3Mb]

NEWS AND BACKGROUND

WATCH: Cyber crime wipes out millions of dollars and a thriving internet business | The Business | 20 May 2013 - Distribute IT was a small web-hosting and domain registry business which had captured a sizeable chunk of the Australian market. But two years ago its systems were hacked for no apparent reason, causing millions of dollars in losses and years of anguish for the business's owners and staff. Watch this report.

US GOVERNMENT: Chinese Hackers Have Stolen Informationspeak. When you get through with his introduction to the Adirondacks you will see why I must step aside.

Hammond on the Adirondacks

And there you have it. These North Woods are what they are. Hammond captures it best but even you could do better than Hammond. Not in words, but in a spiritual way.

How is it that our hearts can describe something that our heads can not?


1. Introduction {#sec1-animals-09-01124}
===============

The failure of equine caregivers to recognise, and subsequently to resolve, expressions of equine stress and pain has been highlighted as a key welfare concern \[[@B1-animals-09-01124]\]. Lack of education, lack of awareness of behavioural indicators of pain and stress, and misinterpretation of a few such behaviours as "naughty" were thought likely factors. The report \[[@B1-animals-09-01124]\] concluded that more research into the links between behaviour, stress and pain is required and that more widespread education is needed in order to enhance equine welfare. A preliminary attempt to provide such education has been undertaken by the Equine Behaviour and Training Association (EBTA) \[[@B2-animals-09-01124]\] in the "Ladder of Fear", a concept extended from the canine "Ladder of Aggression" \[[@B3-animals-09-01124]\], but the subject is still commonly omitted from educational programs.

Behaviouralridden horses, also concluded that individual differences between horses and inconsistencies amongst researchers (e.g. different behaviours considered and different physiological data obtained) make it difficult to obtain an objective association between behavioural indicators and affective states.

The inability of owners to recognise patterns of behaviours of horses that underpin negative emotional states has been explored by \[[@B13-animals-09-01124]\] and has been confirmed to have major welfare implications. This is complicated further by the potential for individual horses to be more, or less, overt in their behavioural expression of underlying emotions, and for the effect of training to mask any emotional response that would otherwise be present \[[@B14-animals-09-01124]\]. Likewise, individual horses cope with stress in different ways \[[@B15-animals-09-01124]\]. Of particular concern is when a horse appears "calm" or "relaxed" but could


two specific criteria. Criterion 1 required at least one of the responses that 4--6 of the experts ($4 \leq N_{Exp} \leq 6$) had selected. Criterion 2 required an absence of all responses selected by zero experts ($N_{Exp} = 0)$. All other participant responses were considered "incorrect".

3. Results {#sec3-animals-09-01124}
==========

The survey received 185 participant responses in addition to the six expert responses. All experts were located in the U.K., as were 79.5% of the participants. Other participants were located in the U.S.A. (6.5%), Canada (4.9%), other European countries (4.9%), Australia (3.2%), South Africa (0.5%) and Brazil (0.5%). The preferred equestrian activities of participants were numbered as 28.1% dressage, 27.6% "happy hacking", 10.8% eventing, 10.8% clicker training, 5.4% natural horsemanship, 4.3% endurance, 2.2% Western riding, 2.2% show jumping and 0.5% polo.A further 8.1% said that that they were "none of the above but enjoyed spending time with horses"; for convenience, this group was labelled "others" in later discussion. When asked about their experience with horses, 137 participants claimed to be experienced horse owners, of whom 20 were also professionals within the equine industry; 8 were experienced former owners of whom 2 were also professionals; 19 had owned horses for fewer than 5 years, 2 of whom were professionals; and 5 were not owners at all. A further 16 selected only the 'professionals' category. Of the 40 stating that they were professionals within the equine industry, 29 were instructors or trainers, with some also classifying themselves as behaviourists. In response to the question about ability to recognise behavioural expressions


is that the experts were aware of potential early behavioural indications that are likely to reflect the onset of negative affect.

[Table 1](#animals-09-01124-t001){ref-type="table"} shows the responses given by the experts to the videos. The 13 affective states have been listed according to how many experts selected that option: for each video clip, the top line lists the responses selected by 4 or more experts, the bottom line lists unanimously rejected responses and the middle line lists the remaining responses. For example, the experts were unanimous in observing that the horse in video 1 exhibited behaviours associated with stress and did not exhibit behaviours associated with anger, enjoyment, excitement, play, relaxation or submissiveness. For each video, there was unanimity with respect to some video/affect pairs and disagreement for others. However,signs of fear, stress and anxiety had no bearing at all on the likelihood of obtaining correct answers. An interesting note, of the total of 21 respondents who perceived stubbornness in at least one video, 19 were experienced owners (current or former) or professionals, again suggesting that equestrian experience did not guarantee accurate reading of behaviour. Such inconsistency is not unprecedented \[[@B24-animals-09-01124]\] and adds weight to the call for further formal identification of behavioural indicators of affective states; as well as dissemination of these indicators, and their underlying causes and welfare implications, to the horse-owning public.

[Figure 5](#animals-09-01124-f005){ref-type="fig"} represents the respondents who perceived negative affective states in the horses and stated whether or not they would condone such training for their own horse. While it is reassuring from an


just right.

I like this glove but the fit is not that great for me. Fingers are to long and sides are just a little tight. Nothing I can't live with. I'm using this glove ad a winter glove and it does a good job keeping my jansa warm in 20* weather. The sweet wipe is super soft and fills great on the skin.

These are certainly a fairly solid set of gloves. They really don't have any padding, which does a fine job of not muting any of the feeling from the bike. But at the same time, long term comfort can be an issue, even with an ergonomic grip. They fit VERY snug compared to previous Giro gloves i've had. I like this because there's no extra materialv. Hornsby; Cause No. 03-14-00505-CV
TO THE HONORABLE COURT OF APPEALS:

      1. The undersigned counsel hereby enters his appearance as lead appellate

counsel for JUDY HORNSBY, Appellee.

      2. Notices may be served on lead appellate counsel via email at

justin@templelawoffice.com.

                                                 Respectfully submitted:


 if (colored==true)
        {
            //Change color of options' text

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            $("#" + selectList + " option[value='"+ encodeURIComponent(subject) +"']").css('color', 'red');
        }
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I currently have two problems with this code:
1- the second encodeURIComponent is not working to deal with options containing simple quotes. Here's an example of error in console:

Uncaught Error: Syntax error, unrecognized expression:
value='est%20le%20type%20d'action%20de']

I tried modifying the line where this happens to make it like the one in the first if clause, but it didn't change anything.
2- Myuntil the moment they open the track via their iTunes or preferred media player. And to do that, you have to head over to their Facebook page (found here) to grab the download. Only thing I can say is that this track utilizes _______ and expertly uses an amazing song by ________ to really build up the energy in true Jane Doze style. So check out Jane Doe 001 here and enjoy your Mashup Mondays!

Frail-Limb-Purity---Mike-Jones-v.-Paper-Diamond--EM1012

Walls-(3LAU-Vocal-Edit)--EM0912

Steerner-x-Corona---Friends-of-the-night-(Chris-Heart-Back-to-90s-Mashup)--EM1012

Rihanna-x-M83---Midnight-City-Diamonds-(Mada-Mashup)--EM1012

Ryan-Nellis-Mashups---Breathing-Magpie-(Patrick-Wolf-x-Jason-Derulo)--EM1012

DJ-BgM---Spectrum-of-Emotions--EM1012

Mercy-In-Da-Paint-(The-Melker-Project-Vs.-RL-Grime-Salva-Trap-Mix)--EM1012

Yoni---Our-City-(Taylor-Swift-x-M83)--EM1012

Rhiannons-Stronger-Island--EM0912

A-Vandals-Lie---Down-In-Flames--EM1012

Someone-Makes-Me-Feel-Dirty--EM0912

Lobsterdust---Its-Fun-To-Be-Young-at-the-YMCA-(Fun.-x-The-Village-People)--EM1012


luck charm for their daughter’s promise of marriage. The piece of jade is kept under the daughter’s pillow at night. Once the jade disappears, it is believed that the daughter now has good luck. Many superstitious families are still unaware that they have dishonest servants.

Mermaid’s Coral A dark blue warty branch that looks like mermaids hair underwater. Occasionally can be found washed up on remote shores or on a collector’s mantle. It is rarely cut and polished and is tend to be left in its natural state.

Moonbloom This is a pure white spinel is shaped like a rose bloom but are very tiny. Rumor has it that they are not natural and are the result of a local wizard gardening with magic.

Mossy Mushroom These emeralds are found inTracts and Brochures

Gospel Tracts and Brochures

A sampling of effective tracts that provide an effective tool for throwing out the seeds of truth into a world that loves to read things. Some people think the days of tracts are over. No way. They still work.

About At The Well

It's all about "rescuing those being led to death."Proverbs 24:11
I'm taking the Light into the darkness created by the abortion industry...
Proclaiming to the blind that Jesus Christ is the answer in dealing with the struggles of life...
Taking the message throughout America that pre-born babies have a right to life; to churches, abortion centers, high schools, colleges and the streets.

In humility correcting those who are in opposition, if God perhaps will grant them repentance, so that they may know the truth, and that


Systems are known for delivering medical devices, such as stents, into a body lumen. Often, such systems include a proximal portion that remains outside the body during use and a distal portion that is disposed within the body during use. The proximal portion typically includes a handle that is held by an operator of the system (e.g., a physician) during use, and the distal portion can include an outer member surrounding a catheter with a stent positioned therebetween. Generally, the operator of the system positions the distal portion within the lumen at a desired location (e.g., so that the stent is adjacent an occlusion). The operator can then retract the sheath to allow the stent to engage the occlusion/lumen wall. Thereafter, the operator removes the distal portion of The undercover agent indicated he would buy the additional methamphetamine, but it would have to be immediately because he was scheduled to leave the city on an afternoon flight.  Both Mendez-Gomez and defendant used the telephone in the hotel room in the presence of the undercover agent to make arrangements for delivery of the methamphetamine.  Mendez-Gomez and defendant were arrested by task force agents as they left the hotel room.

II.

5
Calculation of defendant's base offense level

6
Defendant contends the district court erred in calculating his base offense level under U.S.S.G. § 2D1.1(c) by finding the applicable amount of methamphetamine at issue was three pounds (the total amount defendant agreed to sell to the undercover agent), rather than one pound (the amount defendant actually delivered prior to his


the approximation of adjacent TIR domains. This complex recruits intracellular adapter molecules, including MyD88 (myeloid differentiation factor 88), IRAK (IL-1R associated kinase), and TRAF6 (tumor necrosis factor \[TNF\] receptor-associated factor 6\], to activate signal transduction pathways such as nuclear factor-*κ*B (NF-*κ*B), AP-1 (activator protein-1), JNK (c-Jun N-terminal kinase), and p38 MAPK (mitogen-associated protein kinase) \[[@B21], [@B28]\].

In an animal model of asthma, persistent NF-*κ*B activation in the bronchi is driven by granulocytes *via*IL-1*β* and TNF-*α*, which both induce I*κ*B-*β* degradation, perpetuating the immune response in asthmatic airways \[[@B29], [@B30]\]. IL-1Ra binds tightly to IL-1RI and blocks the activity of either IL-1*α* or IL-1*β*. One of the binding sites of IL-1Ra binds to IL-1RI with high affinity such that the second binding site cannot recruit the IL-1RAcP \[[@B9]\].

2.2. Studies intransmembrane form, ST2L \[[@B42]\]. The structure of ST2L is similar to that of IL-1 receptor type I (IL-1RI), which consists of three extracellular immunoglobulin domains and an intracellular Toll/IL-1 receptor domain. Although the extracellular domain is common to sST2 and ST2L, sST2 lacks the trans-membrane and intracellular Toll-interleukin-1 receptor domains \[[@B15]\].

Beyond its role as a therapeutic target, sST2 has also emerged as a disease biomarker. Previous studies in human patients and animal models have shown that the level of sST2 in sera is elevated in asthma \[[@B43], [@B44]\]. Therefore, it is suggested that sST2 also plays a critical role in Th2 cell-mediated diseases. Administering a recombinant sST2-Fc fusion protein or a sST2 expression vector to asthmatic mice effectively attenuates inflammatory responses and decreases Th2 cytokine production \[[@B45]\]. These


anterior neural plate border at 10.5 hours-post-fertilization (hpf), when they begin to express *sox10*, *foxd3*, *sox9b*, and *tfap2a*. Within the next few hours, three streams of CNCCs can be seen migrating away from the neural tube to more ventral positions. Starting around 15.5 hpf, ectomesenchyme precursors begin to downregulate early CNCC genes such as *sox10*, *foxd3*, *sox9b*, and *tfap2a* [@pgen.1002710-Meulemans1], [@pgen.1002710-Kelsh1] and up-regulate ectomesenchyme-specific genes such as *dlx2a* [@pgen.1002710-Sperber1] and *fli1a* [@pgen.1002710-Brown1]. These ectomesenchyme cells then go on to populate a series of pharyngeal arches from which develops the support skeleton of the jaw and gills in zebrafish, and the jaw, middle ear, and larynx in mammals [@pgen.1002710-Wada1]. Whereas *dlx2a* and *fli1a* are uniquely expressed in the ectomesenchyme lineage, Dlx2a appears to be dispensable for ectomesenchyme formation [@pgen.1002710-Sperber1]at 19 hpf show complementary expression of *fli1a* (green) in ectomesenchyme and *sox10* (red) in non-ectomesenchyme in Antivin-mRNA-injected embryos (n = 5) and un-injected controls (n = 8). Scale bar = 50 µm.](pgen.1002710.g009){#pgen-1002710-g009}

Id2a is required for Bmps to inhibit ectomesenchyme formation {#s2j}
-------------------------------------------------------------

As Id2a and Bmp4 misexpression resulted in similar ectomesenchyme defects, we next examined whether Id2a might mediate the negative effects of Bmps on ectomesenchyme development. To do so, we injected a previously validated translation-blocking *id2a*-MO [@pgen.1002710-Uribe1] into one-cell-stage embryos to deplete Id2a protein. Whereas injection of *id2a*-MO caused no ectomesenchyme defects on its own, injection into *sox10*:Gal4VP16; *UAS*:Bmp4 embryos fully rescued persistent *sox10* and reduced *dlx2a* arch expression, as well as partially rescuing *fli1a* arch expression ([Figure 10](#pgen-1002710-g010){ref-type="fig"}). In contrast, injection of *twist1b* mRNA failed to rescue *sox10* persistence in *sox10*:Gal4VP16; *UAS*:Bmp4 embryos


pME-*hsp70I*:GFP, p3E-polyA, and pDestTol2pA2. To construct stable transgenics, one-cell-stage embryos were injected with vectors and transposase RNA and multiple stable lines were identified for each transgene: *Tg(sox10:Gal4VP16)* (1), *Tg(UAS:Id2a; α-crystallin:Cerulean)* (5), *Tg(UAS:dnTwist1b; UAS:mcherryCAAX; cmlc2:GFP)* (7), *Tg(UAS:dnFgfr1a; cmlc2:GFP)* (6), *Tg(UAS:mKR; cmlc2:GFP)* (2), *Tg(UAS:kikGR; cmlc2:GFP)* (3), *Tg(sox10:dsRED)* (1), *Tg(sox10:LOX-GFP-LOX-hDLX3)* (2), and *Tg(fli1-F-hsp70I:GFP)* (2). In the absence of CRE, *Tg(sox10:LOX-GFP-LOX-hDLX3)^el8^* (referred to as *sox10*:GFP in the [Results](#s2){ref-type="sec"}) drives similar GFP expression as the previously reported *Tg(∼4725sox10:GFP)^ba2^* line but without neural crest cell toxicity [@pgen.1002710-Carney1]. For *sox10*:Gal4VP16/*UAS*:transgene experiments, genotyping for Gal4 and *cmlc2* [@pgen.1002710-Zuniga2] confirmed the observed phenotypes, except for *sox10*:Gal4VP16/*UAS*:Id2a experiments where genotyping for Id2a was performed with primers id2aF: 5′-AGAACACCCCTGACAACACT-3′ and id2aR: 5′- GCTAATACGACTCACTATAGGTACCGGCAGTCCAATTTC-3′.

In situ hybridization, immunohistochemistry, and skeletal analysis {#s4c}
------------------------------------------------------------------

Alcian Blue staining of cartilage and Alizarin Red staining ofof the trigeminal (tg), anterior lateral line (all), otic (ot), and posterior lateral line (pll) ganglia at 36 hpf. No major differences in the pattern of anti-HuC/D staining was observed between uninjected control (n = 6), *twist1a/1b*-MO (n = 6), *sox10*:Gal4VP16 only control (n = 9), and *sox10*:Gal4VP16: *UAS*:Id2a (n = 8) embryos. Scale bar = 50 µm.

(TIF)

######

Click here for additional data file.

######

Cell death and *sox9a* expression in *twist1a/1b*-MO embryos. (A--D) Confocal projections of Lysotracker Red staining in 36 hpf *sox10*:GFP transgenic embryos show increased cell death in the pharyngeal arches (shown in high-magnification views in C and D from the boxes in A and B) in *twist1a/1b*-MO-injected embryos (n = 6) compared to un-injected controls (n = 6). Arrowhead shows increased cell death in more dorsal CNCCs as well. Scale bar = 50 µm. (E) Quantification of Lysotracker-positive cells per arch


Since he was a little boy growing up in Rockford, Illinois, Fred VanVleet has always set the bar high for himself.

Before the 2017-18 season, VanVleet’s second in the NBA, the young Raptors point guard made a list of goals in a journal he keeps. It’s an exercise he has done in the past and revels in, as it helps him mentally prepare for the upcoming year. This isn’t some quick, half-assed list scribbled untidily. VanVleet takes pride in assembling it, going into detail about both individual and team goals and including everything “from minutes played to games played to every stat you can imagine.”

Somewhere on that list, which was created during the preseason, VanVleet wrote the goal: Win Sixth Man of the Year. For an undersized (6-0), undraftedpatterns of metal nanostructures. Thus, we overcome the greatest challenge of Laser Induced Self Assembly by combining simultaneously large-scale character with atomic-scale precision. The proposed process can serve as a platform that will stimulate further progress towards the engineering of plasmonic devices.


Great Britain. I’ve really been thinking about renting a car in Britain to make the journey to Scotland and Ireland a little bit more spontaneous.

My last full day in Berlin was more of a catch-up day than anything else. The first thing on my list was ensure that I had some place to go to after I checked out of the hostel here. I wasn’t really sure where I wanted to go, except that there were two places that I was interested in seeing. The first was Dresden, mostly because of its history during WWII. From what I remember, Dresden was leveled by allied bombings, and when I say leveled I mean flattened. That’s assuming that I remember correctly. The other place was Hamburg… and to be honest,you’re in the right place, that you have the right ticket, or if something does go wrong you’ll end up where you need to be. Fortunately, I’ve done enough traveling that I take most things in stride… but I digress. The first train to Lund was a high-speed train, I was told that we were traveling at 180kph. The thing is, is that the train is pretty plush, so you don’t really feel like you’re traveling that fast. I got into a conversation with two Swedes, one was a production designer for a television show, the other was a student who studied in Florida. It was a lot of fun, and to be honest it was the first real conversations that I have been in with anyone other


 },
        enumerable: false,
        configurable: true
    });
    Object.defineProperty(UxInputInfo.prototype, "length", {
        get: function () {
            var target = this.target;
            if (target.element.tagName === 'UX-INPUT' || target.element.tagName === 'UX-TEXTAREA') {
                return target.value.length;
            }
            return 0;
        },
  Old Testament in order to discriminate. But that's not even the point. 90% of their focal point are all targeted against the LGBT community. The wife, who happens to be self-proclaimed ex-lesbian herself, seems to be very much influenced by her husband, which by the way has made it known that he's going to try to tiptoe through his bigoted words in order to be more politically correct in one broadcast he did a few days ago. He stated that he would be "softer" with his bigotry beliefs against gays and lesbians.

These people I speak about are actually a very nice couple. But what makes them so enraged when speaking about the LGBT community? They were hurt and harassed by many members of our community, but at what


Background {#Sec1}
==========

An important aim for improving TB treatment is to shorten the period of antibiotic therapy without increasing relapse rates or encouraging the development of antibiotic-resistant strains. Pyrazinamide (PZA) is a key component of front-line chemotherapy against *Mycobacterium tuberculosis* (*M. tuberculosis*). It is thought to play an essential role in the shortened 6-month treatment course \[[@CR1], [@CR2]\] due to its ability to act upon the slow-growing drug-tolerant organisms or antibiotic resistant organisms that emerge following treatment with the other front-line drugs, isoniazid (INH) and rifampicin.

In vitro, PZA is still far less potent than in vivo \[[@CR3]\] and its activity against actively growing bacteria in buffered growth media has been found to be extremely low, but increases against stationary phase bacteria either under acidic conditions or if the expressionfor particular functions, functional annotation clustering reports were generated using the DAVID 6.7 bioinformatic resource \[[@CR28]\] with Uniprot IDs as the input. A Bonferroni-corrected EASE-value cut-off of 0.01 (EASE-value being an alternative name for the one-tail Fisher Exact Probability Value used to measure gene-enrichment in annotation terms, compared to proportions of these genes encoded within the genome) was employed along with a minimum gene number per category of five genes (i.e. a category cannot be considered to be enriched unless at least five genes from a function are present). The functional annotation clustering report groups similar categories of annotations together into clusters. None of the up-regulated genes were significantly enriched for any functional categories. Under slow growth, the 226 down-regulated genes in the early recovery phase and the


late recoverySlow growth (69.3 h MGT)Fast growth (23.1 h MGT)Down-regulated in early recoveryDown-regulated in late recoveryDown-regulated in early recoveryDown-regulated in late recoveryAnnotation schemeAnnotationCountBonferroni corrected EASE-valueCountBonferroni corrected EASE-valueCountBonferroni corrected EASE-valueCountBonferroni corrected EASE-valueKEGG_PATHWAYribosome254.00E-24281.70E-26n/an/a74.20E-08GOTERM_MF_FATstructural constituent of ribosome251.60E-21284.10E-25n/an/a71.10E-08SP_PIR_KEYWORDSribonucleoprotein253.60E-21283.40E-24n/an/a71.90E-06GOTERM_MF_FATrRNA-binding211.00E-20232.30E-23n/an/a41.10E-03SP_PIR_KEYWORDSrRNA-binding217.80E-21234.30E-23n/an/a48.10E-03SP_PIR_KEYWORDSribosomal protein253.50E-20285.00E-23n/an/a73.10E-06GOTERM_MF_FATstructural molecule activity255.50E-20282.60E-23n/an/a72.50E-08GOTERM_CC_FATribosome252.50E-19281.30E-21n/an/a79.80E-05GOTERM_CC_FATribonucleoprotein complex258.80E-19285.60E-21n/an/a71.30E-04GOTERM_BP_FATtranslation291.10E-17321.00E-19n/an/a79.20E-06SP_PIR_KEYWORDSRNA-binding227.50E-16251.50E-18n/an/a44.50E-02GOTERM_MF_FATRNA binding261.80E-14271.80E-14n/an/a51.50E-03GOTERM_CC_FATribosomal subunit108.60E-09103.60E-08n/an/a43.20E-03A corrected EASE-value of 0.01 and minimum gene number per category of five was used to perform functional annotation clustering on all down-regulated genes in the early recovery phase (4 h after the addition of 100 μgml^−1^ PZA) or the late recovery phase (2 MGT after the addition of 100 μgml^−1^ PZA) compared to the pre-PZA phase

At a gene-specific level, during the early recovery phase, eight tRNA-encoding genes and 26-ribosomal-protein encoding genes were down-regulated in the slow growing cultures (Table [1](#Tab1){ref-type="table"}, Fig. [2](#Fig2){ref-type="fig"}. brackets, Table [2](#Tab2){ref-type="table"}.), with a single up-regulated gene encoding a ribosomal proteininhibition of this process could be one mechanisms by which PZA targets persisting organisms. Bacteria require *trans*-translation to respond to stress, pathogenesis, and differentiation, which indicates that fast growing organisms also require *trans*-translation to overcome stress \[[@CR36]\]. Based on this mode of action for PZA, it follows that fast-growing organisms would be targeted by PZA. Increased PZA efficacy against fast growing cells could be enabled by potentiators that create stress/reduce metabolism, such as energy inhibitors, in fast growers \[[@CR37], [@CR38]\].

The recovery period co-incident with the down-regulation of ribosomal protein encoding genes seen in this study might reflect a mechanism to reduce the production of toxic proteins caused by the inhibition of trans-translation \[[@CR39]\]. Alternatively adaptation may have occurred through an increase in the mutant frequency and diversity of


Trip

The setting will look very familiar to anyone who has ever played any Mario game before. Bowser has kidnapped Peach, and it’s up to you and Mario to rescue her by venturing to all the corners of the Mushroom Kingdom and facing Goombas, Koopa Troopas, Piranha Plants, and other Mario fare.

If you’re looking for innovation in platforming, Super Mario Run probably won’t satisfy you. It is very much a retread of the old Mario formula, with a dash of Temple Run urgency thrown in. But if you want to take the old familiar Mario with you on the road, this is the game for you. If you’d rather have a richer mobile Mario experience, consider getting a New 3DS XLNew Nintendo 3DS XL Review and CompetitionNew Nintendo 3DSin the game’s Build Shop, which lets you rebuild the Mushroom Kingdom with plants, decorations, and buildings that give you special rewards. Kingdom Building is the third mode on offer, and it’s fairly simple and anemic. Still, the trademark whimsical art style makes it feel more interesting.

If you link Super Mario Run with your Nintendo account, you can unlock a number of extras, including the ability to play as Toad in the single-player mode. You can unlock these extras using Nintendo Points, and you can also earn said points by playing the game.

iPad or iPhone: Which Is Better?

Super Mario Run is available for both iPhones and iPads. There are no aesthetic differences between the two, so it comes down to what screen size you prefer for your games.


A Furniture Salesman Got Hit in the Head and Turned into a Math Genius

A furniture salesman got attacked outside a karaoke bar by a pair of unknown assailants. A few days later, he realized he could see complex geometrical equations everywhere he looked.

Before Jason Padgett was attacked in 2002, he was a jock and party animal who had stopped taking math after a pre-algebra class. "I cheated on everything, and I never cracked a book," he told Live Science.

But a few days after doctors sent him home from the hospital with a severe concussion and a bleeding kidney, Padgett noticed the world looked different.

Soon after the attack, Padgett experienced PTSD and debilitating social anxiety. But at the same time, he noticed that everything looked different. He describes hiscreator services, was named the estate’s latest entertainment adviser. In turn, Carter hired Michael Howe, a former Warner Bros. A&R executive who worked with Prince during his last few years, to start digging into Prince’s storied vault. In May, a Minnesota court ruled that Prince’s only heirs are his six siblings and half-siblings, giving them a bigger say in the estate’s assets.

Those moves, combined with deals set in place before the family officially took over, have paved the way for an upcoming deluge of Prince products. Starting in the fall, fans will finally be able to hear unreleased music, wear newly commissioned Prince clothing, buy tickets to see an orchestra playing Prince material, and hear Prince songs in movies and TV shows. There’s even preliminary talk of a


of a legendary tape circulated among collectors of Prince at home on his piano, playing solo versions of “Purple Rain” and “17 Days” along with a cover of Joni Mitchell’s “A Case of You.” Using a search engine and bar codes assigned to each item shipped to the vault, Howe did some detective work and was able to fish out a TDK cassette in that box of 8,000 that was almost completely unlabeled. “I popped it in and, wow, that’s the one we’ve been looking for,” Howe says. The existence of the nine-song, 35-minute tape was a surprise even to some who collaborated with Prince during that period. “What a find – it’s incredible,” says engineer Susan Rogers, who began working for Prince soon after the tape wasthe new regulations, however, the US-based company has been forced to hold back on discount-driven sale events and accompanying ads for a few months until it figures out new methods of funding discounts and devising ad messages.

“Amazon was beating Flipkart and Snapdeal at their own game of discounting deeply so in the short term. Yes, the new regulations will pull back Amazon slightly because it cannot discount and advertise as freely as it was doing earlier," said Harminder Sahni, managing director at Wazir Advisors, a consulting firm. “But over the long term, the regulations may be good for Amazon. It excels at customer service and offering the widest range of products. If the e-commerce game comes back to basics, Amazon will surely emerge as the winner."

Flipkart and Amazon


and Target Stroke; Honor Roll Awards f...

Abrazo Health Care - Goodyear, AZ

West Valley Hospital (located at 136th Avenue and McDowell Road in Goodyear) is a 188-bed acute care hospital serving the healthcare needs of the residents of the southwest Valley since September 2003. West Valley Hospital has been recognized for high standards of quality and safe patient care by being named a recipient of the Women’s Choice Award as one of America’s Best Hospitals in ...

Abrazo Health Care - Glendale, AZ

Arrowhead Hospital (located at 67th Avenue and AZ-Loop 101 in Glendale) is an award winning 217-bed healthcare facility offering high quality, compassionate care to the community since 1988. Arrowhead Hospital has received national accreditation from the Society of Cardiovascular Patient Care and The Joint Commission (TJC), and madeoccasional harmonic experiments,
in Consonanti stravaganti for example, can sound weird even today.
In short, he is a master and those who enjoy music of this period should
get to know him.

Vartolo included five of these pieces on a disc which
I reviewed with severe misgivings (K617039) that were not limited to
the truly appalling translation of the booklet essay. He is certainly
an enthusiast and writes with authority and accessibility. Of the four
instruments used, three are his own property. The odd thing is that
his notes also state that he uses a copy of a sixteenth century regal
and, besides the Giovanni Cipri organ, two other organs of Bologna,
by Lorenzo da Prato and Baldassare Malamini, but these are in fact not
used. I am also puzzled as to why, having carted the whole works to
the Church


TWO, and two Ellington favorites, DO NOTHIN' TILL YOU HEAR FROM ME and JUST A SETTIN' AND A ROCKIN', are refurbished and shined-up. Svetlana and the band give a warm quirky embrace to GOD ONLY KNOWS from the Beach Boys, and BECAUSE from the Beatles. There are also originals - ALL I WANT, TEMPTATIONS, DANCE IN BETWEEN THE RAINDROPS (Rob Garcia's neat composition which should easily become an anthem for the crowds who come to see the band whether it's south or north of Fourteenth Street), and Svetlana's lovely acknowledgment of her Russian heritage, trumpeter Eddie Rosner's YOU ARE LIKE A SONG, sung in her native tongue. Whatever the language and whatever the material, she swings in admirable ways. As does that band!hundred years before the events in Deserts of Kharak, the Gaalsien were declared outlaws after destroying the city of Saju-ka, killing thousands. Well-adapted to residing in the deep desert, the Gaalsien use hover technology for their vehicles, and rely on speed and hit-and-run tactics, resulting in their vehicles being less armored than the Coalition forces. The Gaalsien also make use of railguns and self-repairing technology, recovered from wrecks in the desert. Tactically, they are described as being similar to the Mongol hordes, relying on mobility and probing for weaknesses before attacking, and the modern United States Armed Forces, using advanced technology to fight an opponent without fully committing.
Kiith Soban
A clan belonging to the Coalition, which provided most of the heavy military hardware for the expedition forces. Known as


= NULL;
			idr_remove(&mspro_block_disk_idr, disk_id);
			put_disk(disk);
		}
	}

	mutex_unlock(&mspro_block_disk_lock);

	return 0;
}

static int mspro_block_bd_release(struct gendisk *disk, fmode_t mode)
{
	return mspro_block_disk_release(disk);
}

static int mspro_block_bd_getgeo(struct block_device *bdev,
				 struct hd_geometry *geo)
{
	struct mspro_block_data *msb = bdev->bd_disk->private_data;

	geo->heads = msb->heads;
	geo->sectors = msb->sectors_per_track;
	geo->cylinders = msb->cylinders;

	return 0;
}

static const struct block_device_operations ms_block_bdops = {
	.open    = mspro_block_bd_open,
	.release = mspro_block_bd_release,
	.getgeo  = mspro_block_bd_getgeo,
	.owner   = THIS_MODULE
};

/*** Information ***/

static struct mspro_sys_attr *mspro_from_sysfs_attr(struct attribute *attr)
{
	struct device_attribute *dev_attr
		= container_of(attr, struct device_attribute, attr);
	return container_of(dev_attr, struct mspro_sys_attr, dev_attr);
}

static const char *mspro_block_attr_name(unsigned char tag)
{
	switch (tag) {
	case MSPRO_BLOCK_ID_SYSINFO:
		return "attr_sysinfo";
	case MSPRO_BLOCK_ID_MODELNAME:
		return "attr_modelname";
	case MSPRO_BLOCK_ID_MBR:
		return "attr_mbr";
	case MSPRO_BLOCK_ID_PBR16:
		return "attr_pbr16";
	case MSPRO_BLOCK_ID_PBR32:
		return "attr_pbr32";
	case MSPRO_BLOCK_ID_SPECFILEVALUES1:
		return "attr_specfilevalues1";
	case MSPRO_BLOCK_ID_SPECFILEVALUES2:
		return "attr_specfilevalues2";
	case MSPRO_BLOCK_ID_DEVINFO:
		return "attr_devinfo";
	default:
		return NULL;
	};
}

typedef ssize_t (*sysfs_show_t)(struct device *dev,
				struct device_attribute *attr,
				char *buffer);

static ssize_t mspro_block_attr_show_default(struct device *dev,
					     struct device_attribute *attr,
					     char *buffer)
{
	struct mspro_sys_attr *s_attr = container_of(attr,
						     struct mspro_sys_attr,
						    MSPRO_BLOCK_ID_SPECFILEVALUES2:
		return mspro_block_attr_show_specfile;
	case MSPRO_BLOCK_ID_DEVINFO:
		return mspro_block_attr_show_devinfo;
	default:
		return mspro_block_attr_show_default;
	}
}

/*** Protocol handlers ***/

/*
 * Functions prefixed with "h_" are protocol callbacks. They can be called from
 * interrupt context. Return value of 0 means that request processing is still
 * ongoing, while special error value of -EAGAIN means that current request is
 * finished (and request processor should come back some time later).
 */

static int h_mspro_block_req_init(struct memstick_dev *card,
				  struct memstick_request **mrq)
{
	struct mspro_block_data *msb = memstick_get_drvdata(card);

	*mrq = &card->current_mrq;
	card->next_request = msb->mrq_handler;
	return 0;
}

static int h_mspro_block_default(struct memstick_dev *card,
				 struct memstick_request **mrq)
{
	return mspro_block_complete_req(card, (*mrq)->error);
}

static int h_mspro_block_default_bad(struct memstick_dev *card,
				     struct memstick_request **mrq)
{
	return -ENXIO;
}

static int h_mspro_block_get_ro(struct memstick_dev *card,
				struct memstick_request **mrq)
{
	struct mspro_block_data *msb = memstick_get_drvdata(card);

	if (!(*mrq)->error) {
		if ((*mrq)->data[offsetof(struct ms_status_register, status0)]
		    & MEMSTICK_STATUS0_WP)
			msb->read_only = 1;
		else
			msb->read_only = 0;
	}

	return mspro_block_complete_req(card, (*mrq)->error);
}

static int h_mspro_block_wait_for_ced(struct memstick_dev *card,


    struct memstick_request **mrq)
{
	dev_dbg(&card->dev, "wait for ced: value %x\n", (*mrq)->data[0]);

	if (!(*mrq)->error) {
		if ((*mrq)->data[0] & (MEMSTICK_INT_CMDNAK | MEMSTICK_INT_ERR))
			(*mrq)->error = -EFAULT;
		else if (!((*mrq)->data[0] & MEMSTICK_INT_CED))
			return 0;
	}

	return mspro_block_complete_req(card, (*mrq)->error);
}

static int h_mspro_block_transfer_data(struct memstick_dev *card,
				       struct memstick_request **mrq)
{
	struct mspro_block_data *msb = memstick_get_drvdata(card);
	unsigned char t_val = 0;
	struct scatterlist t_sg = { 0 };
	size_t t_offset;

	if ((*mrq)->error)
		return mspro_block_complete_req(card, (*mrq)->error);

	switch ((*mrq)->tpc) {
	case MS_TPC_WRITE_REG:
		memstick_init_req(*mrq, MS_TPC_SET_CMD, &msb->transfer_cmd, 1);
		(*mrq)->need_card_int = 1;
		return 0;
	case MS_TPC_SET_CMD:
		t_val = (*mrq)->int_reg;
		memstick_init_req(*mrq, MS_TPC_GET_INT, NULL, 1);
		if (msb->caps & MEMSTICK_CAP_AUTO_GET_INT)
			goto has_int_reg;
		return 0;
	case MS_TPC_GET_INT:
		t_val = (*mrq)->data[0];
has_int_reg:
		if (t_val & (MEMSTICK_INT_CMDNAK | MEMSTICK_INT_ERR)) {
			t_val = MSPRO_CMD_STOP;
			memstick_init_req(*mrq, MS_TPC_SET_CMD, &t_val, 1);
			card->next_request = h_mspro_block_default;
			return 0;
		}

		if (msb->current_page
		    == (msb->req_sg[msb->current_seg].length
			/ msb->page_size)) {
			msb->current_page = 0;
			msb->current_seg++;

			if (msb->current_seg == msb->seg_count) {
				if (t_val & MEMSTICK_INT_CED) {
					return mspro_block_complete_req(card,
									0);
				} else {
					card->next_request
						= h_mspro_block_wait_for_ced;
					memstick_init_req(*mrq, MS_TPC_GET_INT,
							  NULL, 1);
					return 0;
				}
			}
		}

		if (!(t_val & MEMSTICK_INT_BREQ)) {
			memstick_init_req(*mrq,struct request *req)
{
	if (req->cmd_type != REQ_TYPE_FS &&
	    req->cmd_type != REQ_TYPE_BLOCK_PC) {
		blk_dump_rq_flags(req, "MSPro unsupported request");
		return BLKPREP_KILL;
	}

	req->cmd_flags |= REQ_DONTPREP;

	return BLKPREP_OK;
}

static void mspro_block_submit_req(struct request_queue *q)
{
	struct memstick_dev *card = q->queuedata;
	struct mspro_block_data *msb = memstick_get_drvdata(card);
	struct request *req = NULL;

	if (msb->has_request)
		return;

	if (msb->eject) {
		while ((req = blk_fetch_request(q)) != NULL)
			__blk_end_request_all(req, -ENODEV);

		return;
	}

	msb->has_request = 1;
	if (mspro_block_issue_req(card, 0))
		msb->has_request = 0;
}

/*** Initialization ***/

static int mspro_block_wait_for_ced(struct memstick_dev *card)
{
	struct mspro_block_data *msb = memstick_get_drvdata(card);

	card->next_request = h_mspro_block_req_init;
	msb->mrq_handler = h_mspro_block_wait_for_ced;
	memstick_init_req(&card->current_mrq, MS_TPC_GET_INT, NULL, 1);
	memstick_new_req(card->host);
	wait_for_completion(&card->mrq_complete);
	return card->current_mrq.error;
}

static int mspro_block_set_interface(struct memstick_dev *card,
				     unsigned char sys_reg)
{
	struct memstick_host *host = card->host;
	struct mspro_block_data *msb = memstick_get_drvdata(card);
	struct mspro_param_register param = {
		.system = sys_reg,
		.data_count = 0,
		.data_address = 0,
		.tpc_param = 0
	};

	card->next_request = h_mspro_block_req_init;
	msb->mrq_handler = h_mspro_block_default;
	memstick_init_req(&card->current_mrq, MS_TPC_WRITE_REG, &param,
			  sizeof(param));
	memstick_new_req(host);
	wait_for_completion(&card->mrq_complete);
	return card->current_mrq.error;
}

static int mspro_block_switch_interface(struct memstick_dev *card)
{
	struct memstick_host *host = card->host;
	struct mspro_block_data *msb = memstick_get_drvdata(card);
	int rc = 0;

try_again:
	if (msb->caps & MEMSTICK_CAP_PAR4)
		rc


strong predictor of both restenosis and major adverse cardiac events (MACE) in patients with CKD who have undergone PCI.^[@R6]^ As a result; this marker may be of value in the evaluation of therapies investigated to decrease MACE after PCI.

Given the beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs), such as anti-inflammatory, antiplatelet, and its alleviating effect on aspirin responsiveness in drug-resistant patients,^[@R7]^ this study aimed to evaluate the effect of pre-treatment with a single dose of omega-3 on post-PCI hs-CRP level and 30-day MACE in CKD patients. To the best of our knowledge, this is the first trial on the impact of omega-3 in reducing post-PCI hs-CRP and cardiac complications in CKD patients.

Materials and Methods {#s2}
=====================

Patients and study design {#s2-1}
-------------------------

This study is a pilot, prospective, double-blind, and randomizedchanges in post-PCI hs-CRP between the groups. To measure hs-CRP, blood samples were collected at baseline and 24 h after PCI as a primary endpoint. The secondary endpoint was the incidence of MACE over a period of 30 days after PCI. MACE is defined as myocardial infarction, revascularization treatment, and all-cause death. The follow-up study was carried out by telephone interviews to gather information from the patients.

Statistical analysis {#s2-4}
--------------------

Statistical analysis was performed by a statistician who was blind to the study, using Statistical Package for Social Sciences software (SPSS version 21.0). Categorical data were expressed as percentages and Pearson chi-square was used to measure the differences between the groups when required assumptions were met; otherwise, the Fisher's exact test was used. Continuous variables were presented as median (interquartile range) and


EPA and DHA in this trial.

Our results also showed that although the downward trend in the elevation of 24-h hs-CRP in the omega-3 group was seen, there was no significant difference between the omega-3 and control groups. Several factors may contribute to this insignificance including low sample size or high LAD vessel involvement in omega-3 arm. To counter the confounding effect of more LAD distribution in the omega-3 group, we re-analyzed the data, separating those with or without LAD involvement. However, no significant variation was detected in differences between pre- and post-PCI hs-CRP in patients with LAD involvement among the two groups (*p* = 0.822). Also, it is possible that the standard therapy may lead to an insignificant effect of omega-3 on hs-CRP between the groups; however, standardFebruary, Barr has publicly expressed his alarm at how the Obama administration weaponized powerful surveillance tools, along with other methods, to target political foes.

Barr last month appointed U.S. Attorney John Durham to take on this task after numerous delays and empty promises from Barr’s predecessor; this is welcome news as Trump’s base is eager for action.

Barr compared former FBI Director James Comey and his top officers to the Praetorian Guard in an interview last week.

“I just think it has to be carefully looked at because the use of foreign intelligence capabilities and counterintelligence capabilities against an American political campaign to me is unprecedented and it’s a serious red line that’s been crossed,” Barr told CBS News reporter Jan Crawford.

In what can only be described as legitimate obstruction of


Nation” Sunday.

(Important to remember that the security chief of Warner’s committee, James Wolfe was caught leaking classified documents to his journo-girlfriend in 2017 to smear Trump associates and convicted of lying to federal investigators about it.)

Barr also has been attacked by Senator Richard Blumenthal (D-Conn.) and House Speaker Nancy Pelosi (D-Calif.). Former Attorney General Eric Holder tweeted that Barr’s investigation into the investigators is “the height of irresponsibility and politically interferes with both the DOJ/the Intelligence Community. This is a dangerous precedent.”

It’s bad enough that Democrats who are guilty of lying to the American public about Russian collusion for more than two years now want to block Barr’s investigation, but the targets of the inquiry also are speaking out. Comey accused Barr of “echoing conspiracy theories.”

Comey, who saidQ:

Matrix with orthonormal base

I have the two following given vectors:
$\vec{v_{1} }=\begin{pmatrix} 0 \\ 1 \\ 0 \end{pmatrix}$
 $\vec{v_{2} }=\begin{pmatrix} 3 \\ 0 \\ -3 \end{pmatrix}  $
I have to calculate matrix $B$ so that these vectors in $\mathbb{R}^{3}$ construct an orthonormal basis.
The solution is:
$$B=\begin{pmatrix} 0 & -\frac{\sqrt{2} }{2}  & \frac{\sqrt{2} }{2}  \\ 1 & 0 & 0 \\ 0 & -\frac{\sqrt{2} }{2}  & -\frac{\sqrt{2} }{2}   \end{pmatrix}$$
I really don't have any idea how to get this matrix. I'm also confused because I only have 2 vectors.

A:

Maybe these calculations would help you.
We need to find vertor $\vec{v}_3$ such that $\vec{v}_3\perp\vec{v}_1$ and $\vec{v}_3\perp \vec{v}_2$, i.e.
$$
\begin{cases}
(\vec{v}_1, \vec{v}_3) = 0, \\
(\vec{v}_2, \vec{v}_3) = 0.
\end{cases}
$$
Here $(\vec{x},\vec{y})$ is a scalar product of vectors $\vec{x}$ and $\vec{y}$.
If we denote


suffering. After trial, a jury, by special verdict, found that Storm was not negligent. Judgment was entered on the jury's verdict for the defendants. A motion for a new trial was thereafter denied. The plaintiffs have appealed from both the judgment and the denial of their motion for a new trial. We conclude that the judge's failure to instruct the jury on a material issue dealing with the effect of a violation of G.L.c. 90, § 24(1)(a) (operating under the influence of intoxicating liquor), requires that the judgment be reversed and that the case be retried.
There was evidence that March 19, 1980, was sunny and seasonably warm, that Lower Hampden Road is hard-topped and at the accident site is twenty feet wide and divided into two lanes ofhad been affected by his consumption of alcohol. It was not necessary that the evidence be sufficient to prove Storm drunk, Commonwealth v. Lyseth, supra at 558, Commonwealth v. Bernier, 366 Mass. 717, 720 (1975); Nolan, Criminal Law § 555 (1976), for, according to the instruction approved in the Lyseth decision, a motorist can be found to be operating under the influence of intoxicating liquor, in violation of G.L.c. 90, § 24(1)(a), if "the liquor that he had taken influenced [his driving] to any perceptible degree." 250 Mass. at 557. See also Martin & Hennessey, Automobile Law and Practice § 1470 (2d ed. 1967). As indicated, the jury could have so found in this case, and, on the evidence, could have inferred that Storm's consumption of alcohol had


if necessary to render substantial justice." Ibid.
We conclude that the judge erred by not giving an instruction which guided the jury with respect to the legal consequences of a finding that Storm had been in violation of G.L.c. 90, § 24(1)(a), at the time of the accident. Indeed, the instruction requested, on a view of the evidence which the jury could have accepted, falls squarely within the example used by Justice Lummus in his discussion of the second principle. Moreover, we think any potential for unfairness in the instruction arising from the use of the words "further evidence of negligence" would not excuse the need for a suitable instruction on the issue whether Storm was driving while intoxicated. "Even though the request was not strictly accurate in themotion for new trial.
Judgment reversed.
NOTES
[1]  Dorothy J. Petras.
[2]  Lindco, Inc., and Hertz Corporation.
[3]  The judge's final instructions left the question of Storm's speed to be resolved by the jury on the conflicting evidence, and advised the jury of possibly applicable speed limits by reference to the standards set forth in G.L.c. 90, § 17.
[4]  A third principle (which we find not involved in this case) completes Justice Lummus' discussion as follows: "[T]he [general] rule is subject to a genuine exception based, like the rule itself, on practical grounds. Sometimes the issue depends upon the existence of some fact, theoretically subsidiary but practically decisive if found. In such a case, for a judge to ignore the simple concrete test and submit the case upon abstract


// This file is part of Eigen, a lightweight C++ template library
// for linear algebra.
//
// Copyright (C) 2014 Benoit Steiner <benoit.steiner.goog@gmail.com>
//
// This Source Code Form is subject to the terms of the Mozilla
// Public License v. 2.0. If a copy of the MPL was not distributed
// with this file, You can obtain one at http://mozilla.org/MPL/2.0/.

#include "main.h"

#include <Eigen/CXX11/Tensor>

using Eigen::Tensor;
using Eigen::RowMajor;

static void test_orderings()
{
  Tensor<float, 3> mat1(2,3,7);
  Tensor<float, 3> mat2(2,3,7);
  Tensor<bool, 3> lt(2,3,7);
  Tensor<bool, 3> le(2,3,7);
  Tensor<bool, 3> gt(2,3,7);
  Tensor<bool, 3> ge(2,3,7);

  mat1.setRandom();
  mat2.setRandom();

  lt = mat1 < mat2;
  le = mat1 <= mat2;
  gt = mat1 > mat2;
  ge = mat1 >= mat2;

  for (int i = 0; i < 2; ++i) {
    forQ:

Cloudinary multiple image uploaded store in on database

I need to store multiple images uploaded on my database in different field in db.
I upload all images and then through POST method I insert data on db. The first image works but second no.
All field of images have name=image.
<input class="cloudinary-hidden-field" type="hidden" name="image" data-cloudinary-public-id="g4002uhktsiqr7ucg8e2" value="image/upload/v1475179093/g4002uhktsiqr7ucg8e2.jpg#b898624e496e9ba9ce936eba7bc72571be3baa52">

A:

You can change the name of the generated hidden fields using the data-cloudinary-field attribute on the file-upload field, e.g.:
<input name="file" type="file" class="cloudinary-fileupload" data-cloudinary-field="image[]" multiple="multiple" />

When submitting the form, this will result in an array sent over to the server.
I think this should solve the issue.


                      ps.setDouble(2, Double.valueOf("-1.1"));
                        ps.setDouble(3, Double.valueOf("-1.1"));
                        ps.setFloat(4, Float.valueOf("-1.1"));
                        ps.setInt(5, -1);
                        ps.execute();
                "--SPLICE-PROPERTIES useSpark=%s \n" +
                        " on s1.c1 = s2.c2" , bigTable, bigTable, useSpark);
        rowContainsQuery(6, sqlText,"MergeSort", classWatcher);
    }

    @Test
    public void testPickBroadcastEquality() throws Exception {
        String sqlText =
                format("explain select count(*) from %s as a inner join %s as b " +


      s3 + " tab1, " + s3 + " tab2 " +
            " --SPLICE-PROPERTIES joinStrategy=CROSS,useSpark=%s \n" +
            " where tab1.num3=tab2.num1", useSpark
        );

        rs = classWatcher.executeQuery(sqlText);
        resultString = TestUtils.FormattedResult.ResultFactory.toStringUnsorted(rs);
        assertEquals("\n" + sqlText + "\n" + "expected result: " + expected + "\n,actual result: " + resultString, expected, resultString);
        rs.close();

        sqlText =assertEquals("\n" + sqlText + "\n" + "expected result: " + expected + "\n,actual result: " + resultString, expected, resultString);
        rs.close();
    }

    @Test
    public void testDerivedTableWithCrossJoinHint() throws Exception {
        String sqlText = "select c4 from --splice-properties joinOrder=fixed\n" +
                "t4 t\n" +
                ",(select X.c3 from t3 as X, t3 as Y where X.c3=Y.c3) c --splice-properties joinStrategy=CROSS\n" +
                "where c.c3=t.c4 and t.c4 >=37770


          "                   where tab1.a between tab3.a - 1 and tab3.a)", useSpark, useSpark);

            rs = classWatcher.executeQuery(sqlText);
            Assert.fail("Cross join should be invalidate on in join");
        } catch (SQLSyntaxErrorException ignored) {
        }

        rs.close();
    }

    @Test
    public void testCharBooleanColumnsCrossJoin() throws Exception {
        try {
  3 |\n" +
                " 3 |\n" +
                " 3 |";

        try (ResultSet rs = classWatcher.executeQuery(sqlText)) {
            String resultString = TestUtils.FormattedResult.ResultFactory.toStringUnsorted(rs);
            assertEquals("\n" + sqlText + "\n" + "expected result: " + expected + "\n,actual result: " + resultString, expected, resultString);
        }
    }
}


on her own.

'She really pushed people to be more creative,' said marketing coordinator Mary Kate McCormick who sat across from Manuela.'

'She pulled out talents people didn't know they had, and molded people.'

DailyMail.com Publisher Martin Clarke said: ‘Everyone was extremely fond of Manuela (right) who in her time here made a huge contribution to the business. ‘She was hard-working and talented and I have no doubt that she had a very exciting career ahead of her.’

McCormick said that when she saw Manuela at work, she knew she was watching something special.

They were all stunned and upset to hear of their vibrant coworker's tragic death.

'It didn't feel real,' said Andrew Gooss, a graphic designer at DailyMail.com.

'The office is a lot less colorful now.'

'I think a person like that leaves afeet. You look at Katie, just like with Michael, and you realize the differentiator is between the ears. And their hearts. Their appetite for competition, their unwillingness to lose, and their embracing the challenge. And not just the challenge on competition day, which is a huge part, but the challenge of the training grind.”

Ledecky, he said, “has the nerves of an assassin.”

Gemmell has said her overall athleticism is “borderline poor” — but that would appear an exaggeration, at a minimum. Longtime Team USA fixture Jon Urbanchek, who has produced 44 Olympians over a 50-year career, recalled a recent impromptu contest in Colorado Springs where Ledecky and Conor Dwyer — a 2012 Olympic gold medalist and the top-ranked American in the 200 and 400 freestyles — competed to see


had a subsynergistic antiviral effect on CHIKV and SFV replication.[@dkx224-B93] A number of mechanisms associated with ribavirin have been proposed. Of these, the predominant mechanism of action is inhibition of inosine-5′-monophosphate dehydrogenase (IMPDH), which leads to a depletion of cellular GTP pools and is needed for virus replication.[@dkx224-B94] A derivative of ribavirin, ribavirin-5′-sulfamate (Figure [4](#dkx224-F4){ref-type="fig"}), was also described to inhibit SFV replication.[@dkx224-B95] Another nucleoside analogue, 6-azauridine (Figure [4](#dkx224-F4){ref-type="fig"}), is a broad-spectrum antimetabolite that inhibits both DNA and RNA virus replication of CHIKV and SFV,[@dkx224-B93] while replacement of the adenine or guanine core in a nucleoside with 4-fluoroimidazole resulted in 5-fluoro-1-β-[d]{.smallcaps}-ribofuranosylimidazole-4-carboxamide (5-FICAR; Figure [4](#dkx224-F4){ref-type="fig"}), which showed antiviral activity against SINV.[@dkx224-B96]

The carbocylic analogue of cytidine, carbodine (Figure [4](#dkx224-F4){ref-type="fig"}), has been shown to deplete CTP pools by inhibiting CTP synthetase (whichincluding CHIKV.[@dkx224-B102]^,^[@dkx224-B103] Similar to ribavirin, the mechanism of action of mycophenolic acid *in vitro* is based on inhibition of cellular IMPDH activity.[@dkx224-B94]^,^[@dkx224-B103] Brefeldin A, a macrolide lactone antibiotic produced by the fungus *Eupenicillium brefeldianum*, inhibits SINV protein synthesis and RNA replication, possibly due to its interference with the formation of vesicles that were required for viral RNA synthesis.[@dkx224-B104]

Harringtonine (Figure [4](#dkx224-F4){ref-type="fig"}), a cephalotaxine ester derived from the Japanese plum yew, *Cephalotaxus harringtonia*, is known to be an inhibitor of eukaryotic protein synthesis.[@dkx224-B105] It not only demonstrated dose-dependent inhibition of CHIKV during the early events of CHIKV replication after virus entry, but significantly reduced CHIKV RNA and the synthesis of nsP3 and E2 proteins at its non-cytotoxic concentrations (1 or 10 μM).[@dkx224-B106] The mechanism of action of harringtonine has been suggested


stimulation. Chronic stimulation of sensory receptors known to produce subthreshold synaptic potentials in the central processes of the FCE elicits LTA of its neuromuscular synapses. The initial EPSP is decreased by 21%, and the synaptic fatigue is reduced by 17%. These results lead to the hypothesis that the primary event leading to LTA of neuromuscular synapses is depolarization of the motoneuron.F\to F$.

The orbit space of $(X,A)_\infty$ under the action of $A_\infty$ is $X/A$ and we may use the universal property to establish the following diagram $$\begin{CD}
(X,A)_\infty @> e >> X_\infty \\
@V \rho VV    @VVV \\
X/A @>>> (X/A)_\infty
\end{CD}
\label{eq4.3}$$ Note that the inclusion $e\co (X/A)_\infty\to X_\infty$ is the unique $A_\infty$ equivariant extensions of the inclusion of $X$ in $X_\infty$.

Let $A=S^{2n-2}\subset P^{2n-1}(p^t)=X$. Then $(X,A)_\infty$ is the homotopy fiber of the map of degree $p^t$ $$(X,A)_\infty = S^{2n-1}\{p^t\}\lraw S^{2n-1}\stackrel{p^t}{\lraw} S^{2n-1}$$ and the map $e\co S^{2n-1}\{p^t\}\lraw (P^{2n-1} (p^t))_\infty \cong \Ome P^{2n} (p^t)$ is uniquely determined as a $\Ome S^{2n-1}$ equivariant map extending the inclusion of $P^{2n-1}(p^t)$.

One of the main features of the construction $(X,A)_\infty$ is that we can define functorial Hopf invariants using the same formulas as in James [@J].


such that the composition: $$X\tms A_\infty \lraw (X,A)_\infty \stackrel{h}{\lraw} (X\wedge A^{(r-1)}, A^{(r)})_\infty \stackrel{\rho}{\lraw} X\wedge A^{(r-1)}/A^{(r)}$$ is homotopic to the composition: $$X\tms A_\infty \stackrel{1\tms H_{r-1}}{\lraw}  X\tms A^{(r-1)}_\infty \lraw X\wedge A^{(r-1)}_\infty \stackrel{\alpha}{\lraw}  X\wedge A^{(r-1)} \lraw X\wedge A^{(r-1)}/A^{(r)}$$ where $H_{r-1}\co A_\infty \to A^{(r-1)}_\infty$ is any map and $\alpha$ uses the suspension structure of $X$ to collapse $X\wedge A^{(r-1)}_\infty$ to $X\wedge A^{(r-1)}$. \[thm5.1\]

Let $F_n$ be the fiber of the pinch map $$p\co  P^{2n+1} (p^r)\lraw S^{2n+1}$$ for each $n$ and $H_{r-1}$ be any choice of James–Hopf invariants. Then there is a map: $$h\co F_n\lraw F_{rn}$$ such that the composition: $$S^{2n}\tms \Ome S^{2n+1} \lraw F_n \stackrel{h}{\lraw} F_{rn} \lraw P^{2rn+1}$$ is homotopic to: $$S^{2n} \tms \Ome S^{2n+1} \stackrel{1\tms H_{r-1}}{\longrightarrow} S^{2n}\tms \Ome S^{2(r-1)n+1} \lraw S^{2rn} \lraw  P^{2rn+1};$$ in particular, $h_*\co H_{2rn}(F_n)\lraw H_{2rn}fiber of $Q_s\to Q_s\vee E_s$ is $\Ome (E_s\rtimes \Ome Q_s)$ which is a retract of $\Ome (Q_s\vee E_s)=\Ome R_s$ and hence a retract of $\Ome\Dta_s$. This completes the proof with $X_s=E_s\rtimes \Ome Q_s$.

Factorization of $\ol\pat$ {#sec9}
==========================

In this section we will consider the components of $$\ol\pat_n\co \Ome^2 S^{2n+1}\lraw S^{2n-1} \tms V_n = S^{2n-1} \tms \prod\limits_{k\ge 1} S^{2np^k-1}\{p^{r+1}\}$$ we will write $\pat_n(k)\co \Ome^2 S^{2n+1} \lraw S^{2np^k-1}\{p^{r+1}\}$ for the $k$th component, $k>0$ and $\ol\pat_n(0)$ for the projection $\Ome^2 S^{2n+1}\lraw S^{2n-1}$.

We begin by combining the diagram from : $$\begin{CD}
\Ome^2 S^{2n+1}   @ > \pat_n >> \Ome F_n @ >>> \ol F_n \\
@V \Ome \wtit H_{p^s} VV  @VV \Ome h^s V   @VV h' V \\
\Ome^2 S^{2np^s+1} @> \pat_{np} >> \Ome F_{np^s} @>>> \ol F_{np^s}
\end{CD}$$ with the equivalences from


consequently these spectral sequences are isomorphic. From this we conclude

[[@CMN1]]{} $H_*(H_* (\Ome F_n; \mathbb{Z}/p);\bta^{(r)} )\cong H^* (\Ome^2 S^{2n+1};\mathbb{Z}/p)$ as algebras and co-algebras. \[propA1\]

$H_* (H_*(\Ome F_{(p^s-1)};\mathbb{Z}/p);\bta^{(r)})\cong H_*(\Ome S^{2n}_{(p^s-1)};\mathbb{Z}/p)$. \[corA2\]

The later follows by restricting the spectral sequence to the first $p^s-1$ columns.

\[propA3\] Suppose that $X$ is simply connected and $k$ is a field. Suppose that the suspension map: $$\begin{CD}
\sig\co \wtit H_{r-1} (\Ome X; k) @>>> \wtit H_r (X; k)
\end{CD}$$ is onto. Choose a right inverse $\tau$ to $\sig$ and let $T_*\subset \wtit H_* (\Ome X; k)$ be the image of $\tau$. Then $H_*(\Ome X; k)$ is the tensor algebra on $T_*$.

[**Proof**]{}We will use the Serre spectral sequence for the loop space fibration. Note that it is a spectral sequence of $H_*(\Ome X; k)$ modules. Observe that the suspension map can(1\otimes q)=1\otimes \tau (f)q$$ and hence $d^r_{p,q}=0$ unless $p=r$. That is, all non zero differentials terminate on the fiber. Furthermore $$\begin{CD}
d^r_{r,q}\co E^r_{r,q} @>>> E^r_{0,q+r-1}
\end{CD}$$ is a monomorphism since otherwise the kernel would need to be in the image of some differential. Consequently $$\begin{aligned}
\ker d_r &=& F(r+1)\otimes Q(r)\\
\lim d_r &=& F(r+1)\otimes T_*Q(r).\end{aligned}$$ Now define $Q(r+1)=Q(r)/T_*Q(r)$ which completes the induction.

We observe that the spectral sequence is completely determined by $\tau$. We complete the proof by applying the comparison theorem. Let $Y$ be a wedge of spheres together with an isomorphism: $$\begin{CD}
\phi \co H_* (Y;k) @>>> H_*(X;k).
\end{CD}$$ We will define a map of spectral sequences: $$\begin{CD}
E^r_{p,q}(Y) @>>> E^r_{p,q} (X)
\end{CD}$$ $\phi$ defines a isomorphism $F(\phi)\co F(r)(Y)\lraw F(r)(X)$. Since $Y$ is a co-H space, there is a map $v\co Y\lraw S\Ome Y$; we


have tons of dynamics and a deep rich tone! Everyone compliments me on how awesome my bass drums sounds! Super easy to install and its pretty much indestructible! LOVE THIS PRODUCT! D. Mann!!

{"id": "J03965",
"categoryId":"site1DEH",
"name":"Bass Drum Sound Enhancer with Free Batter Side Insert for Bass Drum",
"pageUrl":"/drums-percussion/kickport-bass-drum-sound-enhancer-with-free-batter-side-insert-for-bass-drum",
"thumbnailUrl":"http://media.musiciansfriend.com/is/image/MMGS7/Bass-Drum-Sound-Enhancer-with-Free-Batter-Side-Insert-for-Bass-Drum/J03965000000000-00-120x120.jpg",
"addToCartUrl":"/drums-percussion/kickport-bass-drum-sound-enhancer-with-free-batter-side-insert-for-bass-drum",
"hasFeatures":"0",
"isAccessory":"1",
"message":"This KickPort FX Bass Drum System pre-pack includes a Sonic Enhancement Insert for resonant side, as well as an FX Series batter side head insert. The combination of these implements and their design empower a drummer to enjoy studio-quality bass drum sound in any environment.

The KickPort's design enhances the sound of your kick drum by porting the kick drum in the same manner as a bass reflex speaker cabinet, which boosts low frequencies. It adds ideal dampening directly to the resonant head,connected with a kinesic pointer it also denotes physical proximity to the speaker and obligation to focus one's attention prospectively ; when without kinesic pointers it means that attention must be directed retrospectively within the context.

(b): on the contrary /that/ does not have an immediate denotation of distance; it acquires this only if circumstantially connected with a kinesic pointer, in this case meaning something far from the speaker; if without such a pointer it has the same path as /this/.

One realizes that, whether or not one accepts that some semantic markers can be non-verbally represented, the representation of /this/ or /that/ follows the same procedure as did that of /whale/ or any other categorematic term (23).

The above representation may be verified by the compositional analysis of the kinesic


by Lotman, between _grammar-oriented_ and _text-oriented_ cultures. This indicates the different ways in which two cultures may organize their codes, but the same categories will help us to distinguish different types of sign production in the next chapter (see 3.6.).

The difference between a grammatically oriented and a textually oriented culture has been set out by Lotman (1969, 1971) and is of the greatest importance to the present argument. There are cultures governed by a _system_ of rules and there are cultures governed by a _repertoire_ of texts imposing models of behavior. In the former category texts are generated by combinations of discrete units and are judged correct or incorrect according to their conformity to the combinational rules; in the latter category society directly generates texts, these constituting macro-unitsCure research and consent: the Mississippi Baby, Barney Clark, Baby Fae and Martin Delaney.
Trials using children as subjects are much more problematic from an informed consent perspective than trials on competent adults, although the 'therapeutic misconception' is a central concern in both. The role of famous experiments and the use of one individual's experience to designate and justify a whole category of research have always threatened to undermine the validity of informed consent to research by making it seem to be a validated therapy. In research, the unintended consequence of 'naming' based on goals ('cure') or specific individuals (like the Mississippi Baby) tends to subvert informed consent when the famous case is a 'success', and to prematurely end a line of research if the named subject dies. Names,


a "normal sensation". [Table 1](#t1-cln_69p585){ref-type="table"} displays the test results and respective interpretations. The monofilament was applied to the fingertip of the subject at least three times. The smallest monofilament that was felt by the subjects (as indicated by a "yes" response and a correct identification of the finger that was being touched) was used to generate the test score. The stimulation site was based on the innervation territories of the radial, ulnar and median nerves. The distal points of the thumb, index, middle, ring and little finger as well as the first space between the thumb and index finger on the dorsum of the hand were tested on both hands.

For the two-point discrimination test, the subjects were instructed to say "one" if they felt the sensation at a single  0.2 (0.05 -- 2.0)     0.039\*
  SScG   Middle   2 (0.2 -- 2.0)        0.2 (0.05 -- 2.0)     0.014\*
         Ring     0.2 (0.2 -- 2.0)      0.2 (0.05 -- 2.0)     0.017\*
         Little   0.2 (0.2 -- 2.0)      0.2 (0.05 -- 2.0)     0.007\*
         Dorsum   2 (0.2 -- 2.0)        0.2 (0.2 -- 2.0)


Present systems, devices, and/or manufacturing methods are inadequate, for example resulting in excessive scrapped components. Further limitations and disadvantages of conventional and traditional approaches will become apparent to one of skill in the art, through comparison of such approaches with the various aspects of the present disclosure as set forth in the remainder of the present application with reference to the drawings.import {expect} from 'chai';
import * as Rx from '../../dist/cjs/Rx';
import marbleTestingSignature = require('../helpers/marble-testing'); // tslint:disable-line:no-require-imports

declare const { asDiagram };
declare const hot: typeof marbleTestingSignature.hot;
declare const cold: typeof marbleTestingSignature.cold;
declare const expectObservable: typeof marbleTestingSignature.expectObservable;
declare const expectSubscriptions: typeof marbleTestingSignature.expectSubscriptions;

const Observable = Rx.Observable;

/** @test {skipWhile} */
describe('Observable.prototype.skipWhile', () => {
  asDiagram('skipWhile(x => x < 4)')('should skip all elements until predicate is false', () => {
    const source = hot('-1-^2--3--4--5--6--|');
    const sourceSubs =    '^               !';
    const expected =      '-------4--5--6--|';

    const predicate = function (v) {
      return +v < 4;
    };


and that doesn’t count those whose jobs are internet-dependent.
Our digital agency offers both traditional targeted online display advertising as well as behavioral retargeting. Through an intense discovery process, our team will determine the most optimal marketing mix for your online media plan. We will leverage ad network partnerships for planning the ideal media buys and negotiating the best possible pricing.
The process consisted of a membership trawl to develop a set of agreed principles of Social Marketing to underpin the definition. The process also included an online members vote on these principles; a summary of the survey results is set out in annex two. All members of the participating associations were given opportunities to see the developing definition, comment and make suggestions for improvements. The definition was further refinedDecember 21, 2018, New York – After legal threats and false allegations from Shurat HaDin-The Israel Law Center, the donation platform Donorbox has temporarily suspended the BDS National Committee’s account, disabling its ability to fundraise for its human rights advocacy at the height of the charity season.

Wikileaks revealed in 2013 that Shurat HaDin works in close coordination with the Israeli intelligence agency to pursue legal action against Israel’s critics. The group regularly uses litigation to harass individuals and groups worldwide who challenge Israel’s oppression of Palestinians or endorse boycott and divestment campaigns for Palestinian rights.

Said Palestine Legal Director Dima Khalidi, "The accusations from Shurat HaDin are false and based on flimsy legal theories. Shurat HaDin are themselves engaging in unlawful interference with the BNC’s peaceful grassroots advocacy to


$X_1$, $X_2, \dots$, $X$ be random elements in a metric space $E$ equipped with its Borel subsets ${\ensuremath{{\cal E}}\xspace}$. Further, let $X$ take values almost surely in a separable subset $E_0 \in
{\ensuremath{{\cal E}}\xspace}$. Then $$\begin{gathered}
  \label{1}
  X_n {\ensuremath{\rightarrow}}X \,\, \text{in distribution
  as}
   \,\, n \to \infty\end{gathered}$$ if and only if there is a coupling $({\ensuremath{\hat{X}}\xspace}_1, {\ensuremath{\hat{X}}\xspace}_2, \dots, {\ensuremath{\hat{X}}\xspace})$ of $X_1$, $X_2, \dots$, $X$ such that $$\begin{gathered}
 \label{pontwise}
 {\ensuremath{\hat{X}}\xspace}_n \to {\ensuremath{\hat{X}}\xspace}\,\, \text{pointwise  as}
   \,\, n \to \infty.\end{gathered}$$

[Proof.]{} Let $d$ be the metric. We begin with basic preliminaries. First, assume existence of the coupling and let $h$ be a bounded continuous function. Then (10) yields that $h({\ensuremath{\hat{X}}\xspace}_n) \to h({\ensuremath{\hat{X}}\xspace})$ pointwise as $n \to \infty$ and by bounded convergence, $\int h \,\text{$d$}P_n \in ({\mathbf}{{\ensuremath{\mathbb{N}}\xspace}}\setminus \{1\})^{k_n}$ so $A_{{\mathbf}{{\ensuremath{\hat{Z}}\xspace}}^{k_n}}$ has diameter $< 1/k_n$. From this and we obtain that $$\begin{gathered}
d({\ensuremath{\hat{X}}\xspace}_n, {\ensuremath{\hat{X}}\xspace}) < 1/k_n,  \quad
n{\ensuremath{\geqslant}}N.\end{gathered}$$ Since $N < \infty$ and $\lim_{n\to \infty} 1/k_n = 0$ this implies that $d({\ensuremath{\hat{X}}\xspace}_n, {\ensuremath{\hat{X}}\xspace}) \to 0$ pointwise, that is, (10) holds.

[99]{}

(2007). Skorohod representation on a given probability space. [*Prob. Theo. Relat. Fields*]{} [**137**]{}, 277–288.

(2010). Skorohod representation theorem via disintegrations. [*Sakhya*]{} [**72**]{}, 208–220.

(2011). A Skorohod representation theorem for uniform distance. [*Prob. Theo. Relat. Fields*]{} [**150**]{}, 321–335.

(2013). A Skorohod representation theorem without separability. [*Electron. Commun. Probab.*]{} [**18**]{}, 1–12.

(2015). Glueing lemmas and Skorohod representations. [*Electron. Commun. Probab.*]{} [**20**]{}, 1–11.

(1968). Distances of probability measures and random variables. [*Annals of Mathematical Statistics*]{} [**39**]{}, 1563–1572.

(2002). . Cambridge University Press, Cambridge.

(2002). Some extensions of the Skorohod representation theorem. [*Sankhya*]{} [**64**]{}, 884-893.

(1956).


     case (1):
                    output = new Color(q * 255, value * 255, p * 255, alpha);
                    break;
                case (2):
                    output = new Color(p * 255, value * 255, t * 255, alpha);
                    break;
         break;
                case (5):
                    output = new Color(value * 255, p * 255, q * 255, alpha);
                    break;
                default :
                    throw new Exception("RGB color unknown!");


gods want me to do. Which gives me near complete religious freedom, which in my honest opinion is pretty awesome.

Is God willing to prevent evil, but not able? Then he is not omnipotent. Is he able, but not willing? Then he is malevolent. Is he both able, and willing? Then whence cometh evil? Is he neither able nor willing? Then why call him God.

Sotek, did you write that chant/prayerthingy ? It's awesome. For some reason, I'm unable to write anything similar, even though I do plan to for my book at some point in the future. Would you be interested to give me some of your insight, if ever I need it?

I would be more than willing to help if I can however I'm not sure if Iappears on the RHS of assignment in all steps but this
 *t=new;

Basically the first code assigns 'new' to the pointer of **t, that is *t, and the second code assigns 'new' to the pointer of *t, that is t.
Both seem to be requiring only the single pointer to the head node to be assigned as 'new', yet only the first code works, and second doesn't actually modify the head node value.
What is the explanation for this to happen? Why doesn't the second code work in a similar way to the first?

A:

Because everything in C is passed by value.  So, if you need to assign a new value to an argument to a function, you must add a level of indirection.  if you don't you


is expressed in a cell. Codon optimization may be used to increase the expression level of the protein. The protein is then isolated from the cell by a solubilizing agent that maintains the protein""s conformation. Preferably, the solubilizing agent is a detergent. Preferred detergents include alkyl glucopyranosides (such as C8CP, C10-M, C12-M, Cymal-5, Cymal-6 and Cymal-7), alkyl sucroses (such as HECAMEG), digitonin, CHAPSO, hydroxyethylglucamides (such as HEGA-10), oligoethyleneglycol derivatives (such as C8ES, C8En and C12E8), dodecylmaltopyranoside, and phenyl polyoxethylenes (such as Triton X-100).
The detergent-solubilized protein is then separated from the other cellular debris by capture onto a solid surface (e.g. a spherical or elliptoid bead). The bead has on its surface an antibody or other specific ligand that will capture, orient and concentrate the protein on the surface );

  is(
    content.document.characterSet,
    "windows-1251",
    "Parent doc should report windows-1251 subsequently"
  );
  is(
    content.frames[0].document.characterSet,
    "windows-1251",
    "Child doc should report windows-1251 subsequently"
  );
}


Teenager Murray leads Federer by one set to love. The decisive point was an ace. If the Scot can consistently find his first serve, he may just run away with this. (Sorry - tempting fate again).

Murray 6-5 FedererSurprise, surprise - another break point chance for Murray. This time Federer does not see the funny side. He slams a ball out of the stadium, picking up a court violation and then double faults. Incredible scenes.

Murray 5-5 FedererSo here it is - Murray is serving for the set against the best player of the decade. And the pressure gets to him. He falls behind 15-40 when his first serve deserts him and Federer grinds out a break from a long rally.

Murray 5-4 FedererAnother Federer service game, another string of breakWestern blotting to analyze the expression of PLA~2,~ COX~1~ and COX~2~, we observed that PLA~2~ and COX~1~ expressions were unchanged **(** [**Fig. 2A**](#pone-0075783-g002){ref-type="fig"} **),** whereas the COX~2~ protein expression level was markedly lower (5-fold) in 5-HT~2B~R^−/−^ cells than in WT cells ([**Fig. 2A**](#pone-0075783-g002){ref-type="fig"}). To analyze this pathway more precisely, the different eicosanoid productions were measured, including prostaglandin E~2~ (PGE~2~), thromboxane A2 (TBXA~2~), leukotriene B4 (LTB~4~) and prostacyclin (PGI~2~). We observed no differences according to genotype ([**Fig. 2B**](#pone-0075783-g002){ref-type="fig"}), except in the case of 6-keto prostaglandin F1α (6K-PGF1α), the stable metabolite of prostacyclin (PGI~2~). In 5-HT~2B~R^−/−^ primary calvarial osteoblast cultures, the 6K-PGF1α level was considerably higher (4 fold at D1, and 10 fold at D4) than in the WT supernatant ([**Fig. 2B**](#pone-0075783-g002){ref-type="fig"}). At D4, WT cells treated with the 5-HT~2B~R


antagonist, RS127445 (20 nM), displayed a marked increase (6 fold) in the level of 6K-PGF1α ([**Fig. 2C**](#pone-0075783-g002){ref-type="fig"}). We also noticed a significant increase in the expression of the prostacyclin synthase (PGIS) protein, and a four -fold increase in PGIS activity ([**Fig. 2D**](#pone-0075783-g002){ref-type="fig"}). Furthermore, the levels of 6 ketoF1α (pg/mL) determined in the serum were significantly higher in 5-HT~2B~R^−/−^ mice than in WT mice: (156.1 +/**−** 24.9 in WT mice *vs.* 261.4 +/**−** 28.7 in 5-HT~2B~R^−/−^ mice; n = 10 in both genotypes p\<0.001).

![Prostacyclin over-produced in 5-HT~2B~R^−/−^ osteoblasts.\
A: To determine the role of the PLA~2~ pathway in the 5-HT~2B~R^−/−^ osteoblasts, the expression of PLA~2~ and of COX~1~ and COX~2~ were analyzed by Western blotting. The expression of COX~2~ was markedly lower in the 5-HT~2B~R^−/−^ cells than in the WT cells, whereasQ:

spark whole textiles - many small files

I want to ingest many small text files via spark to parquet. Currently, I use wholeTextFiles and perform some parsing additionally.
To be more precise - these small text files are ESRi ASCII Grid files each with a maximum size of around 400kb. GeoTools are used to parse them as outlined below.
Do you see any optimization possibilities? Maybe something to avoid the creation of unnecessary objects? Or something to better handle the small files. I wonder if it is better to only get the paths of the files and manually read them instead of using String -> ByteArrayInputStream.
case class RawRecords(path: String, content: String)
case class GeometryId(idPath: String, value: Double, geo: String)
@transient lazy val extractor = new PolygonExtractionProcess()
@transient lazy val writer = new WKTWriter()

def readRawFiles(path:


-4*g + 0*b - 5 = -5*b, -g + 3*b = o. Solve -25 = g*i - 3*k, -9 = 5*i + 5*k + 16 for i.
-5
Let n be ((-4)/(-12))/(3/378*6). Solve 2*q + 6 = -u, 8*q = -2*u + 5*q - n for u.
4
Let g(n) = n**2 - 4*n + 6. Let u be g(4). Suppose 2*q - 5*q = -u. Suppose -v - 191*m + 9 = -189*m, 3*m = 9. Solve -q*i - 7 = -5*x, v = 2*x - 0*i - i for x.
1
Let q(z) = -2*z - 25. Let t be q(17). Let o = 59 + t. Solve 5*b + 4*l + 16 = o, -l = 4*b + l + 8 for b.
0
Suppose 2*a = -5*m + 33, 4*a + 6{% include "includes/auth/janrain/signIn_traditional.html" with message='It looks like you are already verified. If you still have trouble signing in, you probably need a new confirmation link email.' %}

‘SNL’ star Darrell Hammond disappointed he didn’t get to stay on as Trump (Atlanta Comedy Theater, July 30)

NEW YORK, NY – MAY 19: Surprise guest Darrell Hammond entertains the crowd at the 2016 Toys”R”Us Children’s Fund Gala on Thursday, May 19 in New York City. One of the largest, single-night fundraisers in New York City, the 2016 Gala raised $4.6 million to support charitable organizations that keep children safe and help them in times of need. (Photo by Mike Coppola/Getty Images for Toys”R”Us)

This was posted Sunday, July 30, 2017 by RODNEY HO/rho@ajc.com on his AJC Radio & TV Talk

Darrell Hammond over 14


X-ROMANCE

X-ROMANCE was initially a project starting in 2015 as an offspring to the original band ROMANCE from 1988 founded by Anders "LA" Rönnblom & Thomas Widmark. In the fall of 2015, Anders was going through a box of old tapes and found the old ROMANCE recordings. He called up Thomas and because he thought that these tapes were too good to be put in a box and stored in a closet. In the following time, they went through all the tracks and re-recorded them. Widmark started to look for musicians in the Stockholm area. There were no problems to find guys who wanted be a part of this project; it was rather harder to find the right guys for the job. X-ROMANCE consists of an experienced line-up withmusicians with a lot of experience in the music industry who now have come together to deliver this fresh Melodic AOR masterpiece called “Voices From The Past”. The album was recorded and mixed at REFLECTION SOUNDS STUDIO, Stockholm and engineered and produced by Tomas Rosenberg & Thomas Widmark. Mastered by Tomas Rosenberg, REFLECTION SOUNDS STUDIO, Stockholm.


summer start date for Michael, a film that Kelly will direct that will star James Franco. The pic is based on the Benoit Denizet-Lewis article “My Ex-Gay Friend,” published in The New York Times Magazine.

Van Sant is exec producing the film with Franco, Vince Jolivette, Scott Reed, Ron Singer and Joel Michaely as producers.

James Franco is set to play Michael Glatze, founder of the (now shuttered) gay twink magazine XY and the short-lived publication Young Gay America who went "ex-gay" and became a poster boy for that movement, according to the NY Post.

The $3.5 million film is being produced by Gus Van Sant and is set to start shooting in New York in July.But in a real world situation, a self-driving car might require particular kinds of maintenance or to be operated only in certain zones. So, it could be that the software was not responsible, but the owner is.

Or take this difficult scenario that Weaver presented to me. Say that a robotic car swerves to avoid a deer, but in doing so, it crashes into another car. If the car did what a good human driver would have, should Google (or whichever self-driving car maker) be responsible for damages in this situation?

Weaver's argument is that the answer is no. The robot itself should be deemed liable. In his preferred legal world, "the car becomes a separate insurable being that potentially provides a faster insurance payout to victims while protecting the


like this. So, in the case of a self-driving car doing the right thing, but getting in an accident anyway, that car—as a legal person—would carry its own insurance. That is to say, damages would be paid by the legal entity of the car.

Another option is that companies like Google might develop business and operational models that allow them to both reduce and take on massive risk by capturing the accompanying rewards. So, instead of selling anyone a self-driving car, Google itself would operate a fleet of ultrasafe vehicles. Certainly the design of the Google car—tiny, light, and speed limited—seems to indicate that Google is preparing for a world where no serious accidents can occur on its watch.

Or one could argue—and this is beyond my legal expertise—that thepleading with Simmons to let her sister go.

Helena became involved in the plot of the National Security Advisor and head of The Family, Derek C. Simmons. In order to manipulate her, Derek had Deborah kidnapped. Willing to do anything to protect her younger sister, Helena agreed to Simmons' demands. She was to help him bypass the president's security when he visited Ivy University in Tall Oaks to give his speech to the American people - a speech that would reveal the truth of the Raccoon City Incident and the U.S. government's involvement and support of the Umbrella Corporation's bioweapons, which could subsequently destroy The Family's designs of keeping the United States as the highest world power.

On the day of the speech, Helena sent out a false alarm over


the radio to tell the agents that a group had entered the campus with the intent of assassinating the president. The agents assigned to protect the president were dispatched to investigate the claim and search the campus for the individuals, leaving Benford vulnerable to Simmons' impending attack. Grief-ridden with what she had done, Helena turned on Simmons. She abandoned her post and rushed to the university to inform them that the alert was fake, though her claims were immediately dismissed as the agents were aware of Helena's past transgressions with the CIA which had left her with a poor reputation.[6] The only agent that gave Helena the benefit of the doubt was DSO agent Leon Scott Kennedy. The two rushed to the president, but by the time theyher and even urged him to follow after her and finally confront his feelings as Ada made her escape. After the situation in China was settled, Helena kept the compact Ada left behind which contained a data chip with evidence against Simmons. When she was presented with her freedom by Leon, she gave the compact to him for when Leon inevitably crossed paths with Ada again.

Helena's only known living family member was her younger sister, Deborah Harper. As Helena was a serious government agent and Deborah was a carefree party girl, it caused tension and conflicts between the two. However, it did little to tarnish the love Helena held for her little sister as she was still fiercely protective of Deborah. This was made extremely evident after Deborah's


extremely furious at the mention of his name and seemed to lose control when speaking to him, immediately lashing out verbally against him. However by the time they had reached China, she seemed to settle into a more stable and rational state even though the feelings for vengeance were the main thing that drove her at that point. Despite this, Helena had her attitude more under control and was more unfazed by other obstacles and more open to other people, as shown by finally start to involve herself with Leon personally. Helena finally settled her loathing of Simmons when she and Leon finally killed him once and for all, finally able to move on.

Helena's relationship with other U.S. government agents is only touched upon briefly. Although Ingrid Hanniganwith our administration?” she asked.

Enrollment figures in the state regents’ report showed 2.6 percent of Iowa State University’s total fall 2017 enrollment was black or African-American and 5 percent was Latino. The University of Northern Iowa figures showed 2.7 percent black or African-American and 3.6 percent Latino. ISU and UNI were not part of the Hechinger Report study.

IowaWatch reporters Lauren Wade and Maria Curi contributed to this story.

TO LEARN HOW IOWAWATCH’S NONPROFIT JOURNALISM IS FUNDED AND HOW YOU CAN SUPPORT IT, GO TO THIS LINK.

This IowaWatch story was republished by The Gazette (Cedar Rapids, IA), the Iowa City Press-Citizen and KCRG-TV-9 produced its own report from the forum under IowaWatch’s mission of sharing stories with media partners.


order to succeed at sports, dating, business, negotiations, exams, or job interviews. Be a winner in any situation!Downloads: 21753 - Shareware - Download Now

Organize your collection of paper books into an electronic library. Add books easily without typing full details: All My Books gets information about the book from the Internet automatically. Track loaners and locate every book in just seconds.Downloads: 22178 - Shareware - Download Now

Album3D Builder allows users to create 3D galleries using their own images, video, sound and animations. They can walk the galleries in real time. Just a good solution for many commercial and exhibition environment, family photo album creators etc.Downloads: 22528 - Shareware - Download NowFiction et Realite au Proche-Orient (1993); received the France-Lebanon Literary Award
 Voyages en cancer (2000); received the Prix Phenix de Literature; English version The Wounded Breast: Intimate Journeys Through Cancer (2001)

References

Category:1943 births
Category:Living people
Category:Lebanese emigrants to the United States
Category:American women novelists
Category:20th-century American novelists
Category:Ball State University alumni
Category:Indiana University Bloomington alumni
Category:Lebanese American University faculty
Category:Northwestern University faculty
Category:University of Illinois at Urbana–Champaign faculty
Category:20th-century American women writers
Category:Novelists from Illinois
Category:American women non-fiction writers
Category:20th-century American non-fiction writers


until the
 * ion driver is moved outside the staging tree.
 */

#ifndef _UAPI_LINUX_ION_H
#define _UAPI_LINUX_ION_H

#include <linux/ioctl.h>
#include <linux/types.h>

/**
 * enum ion_heap_types - list of all possible types of heaps
 * @ION_HEAP_TYPE_SYSTEM:	 memory allocated via vmalloc
 * @ION_HEAP_TYPE_SYSTEM_CONTIG: memory allocated via kmalloc
 * @ION_HEAP_TYPE_CARVEOUT:	 memory allocated from a prereserved
 *				 carveout heap, allocations are physically
 *				 contiguous
 * @ION_HEAP_TYPE_DMA:		 memory allocated via DMA API
 * @ION_NUM_HEAPS:		 helper for iterating over heaps, a bit mask
 *				 is used to identify the heaps, so only 32
 *				 total heap types are supported
 */
enum ion_heap_type {
	ION_HEAP_TYPE_SYSTEM,
	ION_HEAP_TYPE_SYSTEM_CONTIG,
	ION_HEAP_TYPE_CARVEOUT,
	ION_HEAP_TYPE_CHUNK,
	ION_HEAP_TYPE_DMA,
	ION_HEAP_TYPE_CUSTOM, /*
			       * must be last so device specific heaps always
			       * are at the end of this enum
			       */
};

#define ION_NUM_HEAP_IDS		(sizeof(unsigned"It's an age-old problem for regulators, how much transparency there should be," Reid said. "There is an argument of 'let's flush it out,' but in the current situation the weak upturn is a key concern to central bankers, and if you spook markets about banks, then it might further complicate the provision of credit to the economy."

True: it's best to lie to depositors until the last minute, and when everything fails, to pull a Greece and threaten the country with civil war as Alexis Tsipras recently did unless the capital controls imposed on all depositors are implemented.

So to summarize: earlier today the "smartest ECB banker in the room" confirmed it was unable to predict the inflationary or GDP future as far ahead as just one quarter, and now