vaporizer. You control the nicotine so you can back off at your pace, you stop inhaling carcinogens immediately, you’re still doing the oral fixation so you don’t gain weight and, since it’s not smoking, you can legally ‘smoke’ inside. The price for the system varies from model to model but is generally the price of one or two cartons. Again, I don’t smoke, so this is second-hand information. You might want to try it, all the cool kids are doing it.

I live in Williamsburg, and my friends and I would sure like to hear about where to get one of these “trust funds.” I believe these are more prevalent among young Americans in the UES and UWS (and now sadly the LES), and among young Europeans in general.

I’dsuggest finding someone who looks absolutely awful, like their parents dress them in a way to display that they’re “special” children so others aren’t caught off guard, and asking them. Particularly if they’ve got full cases of unwarranted self-importance and Pabst.


time schedule

(iv) the composer’s credit

(v) the composer’s compensation if there is a soundtrack album

(vi) the use and ownership of the music

Fees

In a normal agreement, the composer will do or supervise the music production in addition to writing it. The filmmaker pays the composer for this and sometimes pays for costs associated with production. This includes studio time, engineers, mixers, arrangers, and recording equipment rental. The composer’s fee may also factor in these costs as a Package Deal.

Typically, the filmmaker pays the fee to the composer in installments. The composer receives the first installment when signing the agreement or “spotting”. This is when the production team screen the movie to determine placement and type of music. They receive another when recording of the score begins. They receive the finalmovie.

The producer can also act as a music publisher and label by licensing the music to third parties, even if these parties have no connection to the movie. For example, the producer could license the music to anyone that might want to use it in a commercial.

While the composer has no say in the use or the music and won’t share in the profit from music licensing to third parties, they may be entitled to compensation in at least one form, like public performance.

The share of profit typically divides equally between the publisher and the songwriter. Though the filmmaker receives the publisher’s share for the license, the composer keeps the songwriter’s share regardless of who owns the rights to the music.

Cue Sheets

In the U.S., there is no public


one, not the shadow - if only he stood up.

BUT LET’S TALK ABOUT WHY I EVEN NOTICED THE SHADOW, OKAY?

In another part of the island, shadows play an important part in a series of puzzles. On those puzzles, you often have to ignore shadows cast in order to trace a path of light. Other times you need to trace the path of shadows. In the final puzzle, you must do both.

At the time, I didn’t think much of it beyond solving puzzles, but after seeing this image and thinking about it, I now suspect it to be a commentary on the nature of faith & reason (or “conceptual reasoning” and “instinctive reasoning”), a commentary echoed in other parts of the game. To proceed in life, you cannot abandonStudy suggests link between gut microbiota and Parkinson’s disease

Parkinson's disease sufferers have a different microbiota in their intestines than their healthy counterparts, according to new research.

The study examined the microbial make-up of people with and without Parkinson’s disease to assess whether the condition was associated with alterations to the gut microflora. Led by Filip Scheperjans from the Helsinki University Central Hospital (HUCH), in partnership with researchers at the University of Helsinki, the team found that people with Parkinson’s disease have a different balance of bugs in their guts compared to healthy controls. "Our most important observation was that patients with Parkinson's have much less bacteria from the Prevotellaceae family; unlike the control group, practically no one in the patient group had a large quantity of bacteria from this


an edit with a new alternative after Jack Creasey's answer:

Edit2:
Inverted

A:

Would this circuitry work with 5.1V Zener diode to protect a Nano input?

Short answer: NO
A Zener is crude when it comes to use as a clamp, and the voltage variation will impact the A/D conversion on your Arduino Nano.
A typical Zener such as this has a range of voltage from 4.85 - 5.2 V for a nominally 5.1 V Zener. At 5.2 V you will already have significant current into the Nano intrinsic diode on the supply side.
If you want to protect the input then use a device such as the TLV6001 to buffer the input signals.

simulate this circuit – Schematic created using CircuitLab
The TLV6001 is rated for rail-rail operation and so allows the fullAs Republicans began the process of dismantling ObamaCare this week, they also struggled to dismantle an offensive anti-police painting that is still hanging on a wall in a Capitol Hill hallway.

Speaker Paul Ryan (R-Wis.) said on Thursday that he was confident the painting depicting police officers as pigs would soon come down from a wall in the Capitol, calling it “disgusting.”

Via The Hill:

“This is disgusting and not befitting of the Capitol,” Ryan told conservative radio host Mike Gallagher. The Speaker’s remarks came a day after Rep. Dave Reichert (R-Wash.), a former sheriff, argued in a letter to the Architect of the Capitol (AOC) that the painting should be removed because it violates the rules of the annual high school art competition run by the AOC. The rules prohibit


Batteries typically are constructed with a set of anode plates and a set of interleafing cathode plates, which are spaced apart by separators infused with an electrolyte. The anode plates must be electrically connected to the battery anode terminal, and the cathode plates must be electrically connected to the battery cathode terminal. For the sake of rigidity of the assembled sets of anode and cathode plates, the connection between the plates and the terminals is typically mechanical as well as electrical, and is accomplished with an "end connector" of some type.
This electromechanical attachment of the anode and cathode plates to their respective terminals through end connectors is one of the more labor intensive and fault intensive aspects of battery construction. Ideally, the end connector assembly would rigidly supportmight help in identifying patients with subclinically compromised photoreceptor function.

Cone-mediated visual function is essential for patient quality of life and, thus, is clinically relevant as an endpoint. Although rod photoreceptor loss has been shown to precede cone loss, foveal cones are also affected in the early stages of AMD. Johnson et al demonstrated that cone photoreceptor cells overlying either hard or soft drusen were found to have morphological and molecular abnormalities indicative of photoreceptor degeneration and Muller glial cell activation.[@b23-opth-12-1325] In addition, it has been shown that loss of integrity of rod photoreceptors may lead to a corresponding vulnerability of cones.[@b24-opth-12-1325],[@b25-opth-12-1325] Fundus reflectometry studies have shown disruption of the cone matrix in early AMD,[@b26-opth-12-1325],[@b27-opth-12-1325] and additional disease pathways involving cone photoreceptors have been suggested due to changes in


it showed good short-term and long-term repeatability based on high ICC values, although these results are within the context of a small pilot study. Our finding that the baseline cone threshold is compromised in early AMD is consistent with results from studies based on mesopic microperimetry,[@b38-opth-12-1325],[@b39-opth-12-1325] which have also shown good test--retest repeatability.[@b61-opth-12-1325]

Furthermore, the recovery half-life parameter showed good short-term and long-term repeatability. We note that the recovery half-life data are heavily skewed to the right. This suggests that this parameter may not be well-modeled by the assumption of normality and a log transformation of the data was appropriate. In fact, a log transformation of the data results in a significant *p*-value comparing older normal and AMD subject groups (*p*=0.0409). Similar statistical properties have been found for rod-mediatedaddition, the majority of AMD studies reporting positive findings with photostress recovery endpoints have employed the use of sustained multi-second bleaching (≥10 s).[@b42-opth-12-1325]--[@b44-opth-12-1325],[@b47-opth-12-1325],[@b66-opth-12-1325],[@b68-opth-12-1325],[@b69-opth-12-1325],[@b76-opth-12-1325],[@b80-opth-12-1325],[@b81-opth-12-1325] Recent AMD studies such as those of Dimitrov et al have examined both rod and cone photopigment regeneration and used separate bleaching methods for each (11 ms photoflash for rods, 45 s continuous light for cones).[@b68-opth-12-1325],[@b69-opth-12-1325]

For the present study, a specialized device, Ora LUX, was constructed to ensure a sustained, repeatable, and stable photobleach that effectively bleaches up to 84% of cone photoreceptors. In addition, we conducted a detailed analysis to ensure that the bleaching paradigm was well within the safety limits of exposure established by industrial standards. With the ideal endpoint, a bleach of 90 s (as used here) may have superior diagnostic capabilities


   vb.forwardTo(getRequestContext());
    }

    protected void setValues(String value) {
        PolicyResourceComparator rc = new PolicyResourceComparator(value);
        propertySheetModel.setValue(ATTR_SERVICE_TYPE, rc.getServiceType());
        propertySheetModel.setValue(ATTR_CLASS, rc.getClazz());
        propertySheetModel.setValue(ATTR_WILDCARD, rc.getWildcard());
        propertySheetModel.setValue(ATTR_DELIMITER, rc.getDelimiter());
        propertySheetModel.setValue(
            ATTR_ONE_LEVEL_WILDCARD, rc.getOneLevelWildcard());
        propertySheetModel.setValue(ATTR_CASE_SENSITIVE, rc.getCaseSensitive());
    }

    private PolicyResourceComparator getValues()
        throws AMConsoleException {
        String serviceType = (String)propertySheetModel.getValue(
        }

        PolicyResourceComparator c = new PolicyResourceComparator();
        c.setServiceType(serviceType);
        c.setClazz(clazz);
        c.setDelimiter(delimiter);
        c.setWildcard(wildcard);
        c.setOneLevelWildcard(oneLevelWildcard);
        c.setCaseSensitive(caseSensitive);
        return c;
    }

    public void handleButton1Request(RequestInvocationEvent event)
        throws ModelControlException {
        try {
            PolicyResourceComparator rc = getValues();


массиве для сдвига и вставки */
binarysearch(_numb, ??? , current_num_tables);
/* Чему равно значение 'index' здесь, и какой в нем смысл? */
if (t[index].numb != NULL)
    for (i = 1; i < index; i++)
    {
        t[i].numb = t[i - 1].numb;
    }
/* Выше происходит сдвиг элементов (возможно, для освобождения места для нового элемента?). Ниже - увеличивается размер таблицы. А где вставка элемента, индекс которого мы получили в бинарном поиске, и для которого освобождали место? Зачем мы проводили этот бинарный поиск, если не используем его результат? */
current_num_tables++;
return;

Решение: нарисовать на бумажке таблицу, ее устройство и действия программы. Лучше таких рисунков сделать штук 5-6, для разных состояний таблицы (пустая, 3 элемента, 10 элементов, вставка в начало, в середину, вcompletely.
The ConvertTo-Html Object takes in a pretty limited set of objects which it knows how to convert, a PsCustomObject (which is what Import-Csv gives you) will work fine, however a Hashtable will not, so instead of outputting the Inner data, it will give you System.Collections.Hashtable+KeyCollection as that's all it knows how to get (I believe it just calls .ToString() on it and returns that)
If you'd like to loop through each member of the result of Group-Object and turn each Value into its own HTML Table then you can use this:
$ImportedCsv | Group-Object -Property Email | ForEach-Object {
    $_.Group | Select-Object * -Exclude 'Email' | ConvertTo-Html
}

edit in to send multiple emails:
$ImportedCsv | Group-Object -Property Email | ForEach-Object {
    $ToAddress = $_.Name


and the Federal Government." Gregory v. Ashcroft, 501 U.S. 452, 457, 111 S.Ct. 2395, 115 L.Ed.2d 410 (1991). The states possess inherent law-making authority  both with respect to statutory and common law. See New York v. United States, 505 U.S. 144, 161, 112 S.Ct. 2408, 120 L.Ed.2d 120 (1992) (holding that Congress may not commandeer the legislative processes of the States). When a state statute or common law conflicts with the United States Constitution, we will declare the state law to be null and void, but we have no authority to alter or reinterpret state law.
By ignoring the deference normally given to state court decisions concerning state law, we misinterpret Washington's accomplice liability statute and find a federal due process violation based on a phantom conflict between308, 315 (2001). Directly quoting the reasoning of the Washington Supreme Court is neither improper for a Washington Court of Appeals, nor an improper application of state law. Therefore, the panel majority's conclusions directly conflict with the Washington Supreme Court's and the Washington appellate courts' decisions about the scope of accomplice liability and the propriety of the jury instructions in Sarausad's case.
We must accept as binding the Washington Supreme Court's express approval of the instruction and the statute as accurate and proper statements of Washington's accomplice liability law. Bradshaw, 546 U.S. at 76-78, 126 S.Ct. 602. Having determined that there was no state law error from the use of the accomplice liability jury instruction in Sarausad's case, the question becomes whether RCW § 9A.08.020, by defining accomplice liability,


the panel majority conflicts with this court's opinion in Lambert v. Blodgett, 393 F.3d at 975-76, because it fails to find (and, as discussed above cannot find) that the state courts' legal conclusions were objectively unreasonable or contrary to established Supreme Court precedent. Rather, the panel majority proceeds to undertake what amounts to a direct review of the allegedly improper jury instruction under Estelle, 502 U.S. at 71-72, 112 S.Ct. 475. See Sarausad, 479 F.3d at 689-94. The Supreme Court has reiterated time and time again after Williams, that a federal court cannot grant habeas relief by undertaking a de novo review and reaching a different conclusion than the state courts. See Yarborough v. Alvarado, 541 U.S. 652, 665, 124 S.Ct. 2140, 158 L.Ed.2d 938 (2004); Woodford, 537the study of more mobile and unstructured regions. To provide restraints for determining the full 3D structure, we will measure direct interatomic distances between key residues in Tia1 and between the protein and its ligands. We will use a selective isotope enrichment strategy that is not reliant on complete shift assignments. Electron microscopy methods after particle classification and multidimensional reconstruction will be used to characterize the morphology of Tia1, providing vital long distance information and particle shape restraints. These studies will culminate in a high resolution structure of Tia1. This project will proved extensive training opportunities in the biology and biochemistry of a protein in stress granules , cryogenic electron microcopy and polarization enhanced multidimensional SSNMR spectroscopy This training will enable me to apply structural biology techniques to


Rupture of both papillary muscles after acute myocardial infarction: a case report.
The authors report a case of transthoracic echocardiographic left ventriculography and surgical pathology findings of a patient with rupture of both papillary muscles after acute myocardial infarction.  end

        local lastCompletedOp = GetLastCompletedOperation(campaign)
        if GetNextOperation(campaign, lastCompletedOp).opID == operation then
            for i, v in campTable[campaign][lastCompletedOp] do
                if v.allPrimary == true then
                    return true
                end
            end
        end
    end


Pages

There Is More Than One Way to Make Black

Recently I was talking with a young artist about his work. He's not a visual artist, but the conversation reminded me of my first painting class, a night class at a local art college.This young actor thinks there is only one way to get the effect he wants. I was saying there IS more than one way, but it might take more thought and work. I likened it to squeezing black paint out of a tube. Which brings me to my art class story.

I had done a lot of drawing prior to taking the painting classs, but hadn't had a lot of success working with color. Part of that was because like a lot of beginning artists, I relied tooof the court. BATCHELDER, J. (pp. __-__), delivered a separate concurring opinion. COLE, J. (pp. __-__), delivered a separate opinion concurring in part and dissenting in part.

OPINION

1
SILER, Circuit Judge.

2
Respondent, Ricky Bell, Warden ("State"), appeals the issuance of a writ of habeas corpus to Petitioner, Abu-Ali Abdur'Rahman ("Petitioner"),1 vacating Petitioner's sentence of death for first-degree murder on the grounds of ineffective assistance of counsel at the sentencing phase of Petitioner's trial. Additionally, Petitioner cross-appeals the denial of his petition for a writ of habeas corpus seeking relief from his conviction for first-degree murder. We reverse the district court's finding that Petitioner was prejudiced by his trial counsel's deficient performance at the sentencing stage and vacate the portion of the district court's judgment granting the petition for a writ of


and files of trial counsel showed that they failed to investigate and obtain available information concerning petitioner's psychiatric examination at St. Elizabeth's Hospital, Washington, D.C., following his incarceration for assault on or about the day of his discharge from the Army, despite the fact that part of this information was sent to MTMHI [Middle Tennessee Mental Health Institute] per their request.

24
10. Testimony and files of trial counsel showed that they failed to investigate and obtain available information concerning petitioner's institutional records while in the federal prison system.

25
11. Testimony and files of trial counsel showed that they failed to investigate and obtain available information concerning petitioner's psychiatric examination following petitioner's 1972 killing of a fellow prisoner while incarcerated for the assault referenced in paragraph 9 above.

26
12. Trial counsel hasof correctness listed in § 2254(d):

50
First, it is evident that § 2254(d) does not codify Townsend's specifications of when a hearing is required. Townsend described categories of cases in which evidentiary hearings would be required. Section 2254(d), however, does not purport to govern the question of when hearings are required; rather, it lists exceptions to the normal presumption of correctness of state-court findings and deals with the burden of proof where hearings are held. The two issues are distinct, and the statute indicates no assumption that the presence or absence of any of the statutory exceptions will determine whether a hearing is held.

51
Id. at 10 n.5. Thus, this passage indicates the continuing viability of Townsend's statement that a districtcourt may order an evidentiary hearing to settle disputed issues


for a sentence of less than death." Id. Petitioner's reliance upon Lockett is misplaced as it involved the presentation of evidence of mitigating circumstances that was deemed not to fit within Ohio's narrow death penalty statute. See id. at 594-95. In the instance case, Petitioner did not "proffer" any evidence that the jury was precluded from considering. Petitioner also relies upon Glenn v. Tate, 71 F.3d 1204, 1211 (6th Cir. 1995), for the proposition that "[o]ur sister circuits have had no difficulty in finding prejudice in sentencing proceedings where counsel failed to present pertinent evidence of mental history and mental capacity." Id.

66
Petitioner did not suffer prejudice sufficient to create a reasonable probability that the sentencing jury would have concluded that the balance of aggravating and mitigating factors didsentencing jury was unconstitutionally vague and overbroad, relying upon Coe v. Bell, 161 F.3d 320 (6th Cir. 1998), and Houston v. Dutton, 50 F.3d 381 (6th Cir. 1995). The district court concluded that even if the instruction was vague, any error caused thereby was cured by the Tennessee Supreme Court's application of a constitutional narrowing construction to the aggravating circumstance. The State argues that if the instruction was unconstitutionally vague, any error was harmless due to the jury's finding of other aggravating circumstances.

69
In Maynard v. Cartwright, 486 U.S. 356 (1988), the Court addressed the vagueness of a similar instruction and set forth the following standard to employ:

70
Vagueness challenges to statutes not threatening First Amendment interests are examined in light of the facts of the case at hand; the


not show any prejudice as defined by Strickland because under Cuyler v. Sullivan, 446 U.S. 335 (1980), "a defendant who shows that a conflict of interest actually affected the adequacy of his representation need not demonstrate prejudice in order to obtain [habeas] relief." Id. at 349-50. Petitioner argues that the third-party fee arrangement created a conflict of interest for his trial counsel because Boyd, the source of payment, was involved in the crime due to having allegedly supplied the shotgun used by Petitioner. However, the next sentence in Cuyler is dispositive of Petitioner's claim. Cuyler strictly requires that "until a defendant shows that his counsel actively represented conflicting interests, he has not established a claim of ineffective assistance. . . . [T]he possibility of conflict is insufficient toof this delay.

114
Second, Petitioner argues that he was prejudiced by his trial counsel's failure to investigate and present a lab report showing that no blood was found on the clothes he was allegedly wearing during the offense. The district court correctly held that such evidence would not have created a reasonable doubt about guilt because although there was testimony that Petitioner was wearing a long dark coat on the night of the offense, there was no evidence that at the time of the homicide Petitioner was wearing the clothes seized later from his apartment. See Abdur'Rahman, 999 F.Supp. at 1096.

115
Finally, Petitioner argues that trial counsel's failure to investigate his mental history, especially his diagnoses of Post-Traumatic Stress Disorder and Borderline Personality Disorder, prejudiced him at the guilt stage


1988, only 1.1% of habeas corpus petitioners received a full hearing at the district court).

138
Abdur'Rahman's counsel was constitutionally ineffective at sentencing due to counsel's utter failure to investigate or present available mitigating evidence. In order to prove ineffective assistance of counsel, Abdur'Rahman must fulfill the familiar two-prong requirement of Stricklandv. Washington, 466 U.S. 668 (1984).

139
First, the defendant must show that counsel's performance was deficient. This requires showing that counsel made errors so serious that counsel was not functioning as the "counsel" guaranteed the defendant by the Sixth Amendment. Second, the defendant must show that the deficient performance prejudiced the defense. This requires showing that counsel's errors were so serious as to deprive the defendant of a fair trial, a trial whose result is reliable.

140
Id. at 687. As notednot prejudiced by counsel's failure. To demonstrate prejudice, Abdur'Rahman "must show that there is a reasonable probability that, but for counsel's unprofessional errors, the result of the proceeding would have been different. A reasonable probability is a probability sufficient to undermine confidence in the outcome." Strickland, 466 U.S. at 694. He need not show that counsel's performance more likely than not affected the outcome of the case. See id. at 693-94. Instead, "[w]hen a defendant challenges a death sentence . . .,the question is whether there is a reasonable probability that, absent the errors, the sentencer - including an appellate court, to the extent it independently reweighs the evidence - would have concluded that the balance of aggravating and mitigating circumstances did not warrant death." Id. at 696.

145
Counsel's


      int length = 8000;

         command->Parameters->Append(command->CreateParameter(_bstr_t(parameterName),adWChar,adParamInput, length, stringType));
      }
      else
      {
         VARIANT int64Variant;
         int64Variant.vt = VT_I8;
         int64Variant.llVal = value;

         command->Parameters->Append(command->CreateParameter(_bstr_t(parameterName), adBigInt,adParamInput, sizeof(__int64), int64Variant));
      }
   }
}

for Bergdahl, to effectively make the prisoner swap public before it occurred.

“We had discussed with Congress the possibility that something like this might occur,” he said. “Because of the nature of the folks that we were dealing with and the fragile nature of these negotiations, we felt it was important to go ahead and do what we did.”

On Thursday, the Associated Press, citing "three congressional officials," reported that the administration has told senators it didn't talk to Congress about the deal because the Taliban had threatened to kill Bergdahl if news of the talks leaked before the swap was made.

Marie Harf, the State Department's deputy spokesperson, declined to say whether the Obama administration received a specific threat from the Taliban that it would kill Bergdahl if the deal


officially come out until October of 1993, on the band’s first full-length album, “Pussy Whipped.” In the clip, Hanna strips off a white T-shirt, Sharpied with the words “RioT GrrrL,” to reveal a yellow-blue-and-white minidress over knee-high white boots. You might momentarily think, Austin Powers, but not for long. “These are my tits!” Hanna yells, and then, “This is my ass!,” as she turns to flip up her dress and quickly moon the crowd. She starts stomping in place as she yells, “And these are my legs!” She is double-daring you now to figure out what to do. She sexualizes herself before you can, dragging in one of childhood’s most sexualized characters, Little Red Riding Hood, and rewriting the wolf’s deceptive patter for this new Red: “These arework under the influence of alcohol! . a warm loft the key thing to remember is ventilation – you must keep a 50mm gap between the roof and the rigid insulation board.

So fitting insulation in your loft, attic or roof space is a great way to improve . semi-detached house with gas central heating can start at about ￡50 for DIY . other materials,make sure you use appropriate loft insulation materials and methods.


distinctions among ex-offenders each applied rational-basis review. See Miller v. Carter, 547 F.2d 1314, 1316 (7th Cir.1977) (holding that "[s]uch distinctions among those members of the class of ex-offenders are irrational"); Nixon v. Commw., 576 Pa. 385, 839 A.2d 277, 289 (2003); Mixon v. Commw., 759 A.2d 442, 451 (Pa. Commw.2000). Plaintiffs have not asserted a fundamental right, as explained above, and are not members of a suspect class, Cutshall v. Sundquist, 193 F.3d 466, 482 (6th Cir.1999). Therefore, the challenged distinction is reviewed under the rational-basis test.
This court has already held that the state has a rational basis for treating sex offenders differently from other offenders by requiring them to register. Id. at 482-83. Therefore, plaintiffs again rely on the interaction of the SORA with the SACA.Plaintiffs argue that no rational basis exists for treating sex offenders differently from other offenders because, under the SACA, a court has determined that they are "not dangerous and . . . do not pose a threat to the public." To be accurate, under the SACA, the court makes only a determination "that setting aside the conviction is consistent with the public welfare." Mich. Comp. Laws § 780.621(9). However, when the state court finds that setting aside the conviction of a sex offender is consistent with the public welfare, it knows that the sex offender will continue *967 to be subject to the registration requirements of the SORA. Therefore, the state court determines that a sex offender does not pose a threat to the public only to the


extent that the offender remains on the PSOR. Furthermore, the state court's determination is not a guarantee that the offender poses no threat. Despite the determination under the SACA, it remains rational for Michigan to seek "to provide law enforcement and the people of [Michigan] with an appropriate, comprehensive, and effective means to monitor those persons who pose such a potential danger." Id. § 28.721(a). Therefore, plaintiffs' equal protection challenge fails.

IV.
For the foregoing reasons, we affirm the decision of the district court.
NOTES
[*]  The Honorable Joseph M. Hood, United States District Judge for the Eastern District of Kentucky, sitting by designation.
[1]  Plaintiffs obscure the correct analysis by urging us to apply the "stigma plus" test. That test applies only to procedural due process claims. See Doe XIV,memory
location, one step at a time. The loop is a natural abstraction over this
linearity, representing a jump from the end of a line of instructions back to
the beginning.

The problem being, as you point out, that it imposes a fixed order, regardless
of whether the problem domain requires such an order.

In database programming one of the biggest challenges for beginners is to stop
thinking in terms of loops; to learn to "think in sets".

~~~
gwu78
Thanks for this. I'm relieved to know I'm not thinking the "wrong" way. :)

But, honestly, I could not articulate the problem as you have. I wish I had
your knowledge. The idea of a "jump" really captures it. setjmp. goto. It's
navigating memory. And nothing more.

I can visualize the problem, sort of - I just intuitively feel like sets,
Lisp-like lists,


help, and residential care supports through the Fair Deal scheme to more sustainable levels.

However, 57% of respondents said that some contribution should be made towards home care by elderly people themselves.

There were a wide range of views on how means testing would work, including via a minimum threshold beneath which service users would not pay for home care.

But it was suggested that means-tested user contributions could only be legitimately introduced if the service provided was comprehensive and of a high quality, and as long as if service users were given a choice of carer and influence over the services provided.

It has also suggested that carers should have a minimum level of training.

Citing investments in childcare and early childhood education, which have increased the level of training for thoseHave you ever thought of looking for a connection between learning difficulties and the eye movements of people who have them? My NLP work with learning difficulties has proven that there is a connection. Let’s explore it.

Most people with learning difficulties are very ungrounded and distractible. This distractibility is exactly where the connection between eye movements and learning difficulties lies. Have you ever asked a person with trouble with e.g. reading comprehension how s/he saw a page of text? What did the text do? Did it move? If yes, how? Did the person see only one screen in their mind’s eye? Or did s/he see several screens with different action on each screen? And did s/he see it or did s/he try to hear or feel it first?


Q:

What are the application of result "Every compact metric space is separable"?

What are the application of result "Every compact metric space is separable"?
I wanted to do some exrecise problem which uses the result Every compact metric space is separable so that I can understand the result upto the fullest.
Please suggest some exercise problems...
Thank you

A:

The result has as immediate consequence that a compact non-separable space is not metrisable, so e.g. $[0,1] \times [0,1]$ in the order topology induced by the lexicographic order (the lexicographically ordered square) is not metrisable.

of complexifying the space in which the four-dimensional loop momenta live, from $\mathbb{R}^{1,3}$ to $\mathbb{C}^4$, and taking the integrals on both sides of to be over a product of contours running along the real axis. We can imagine evaluating the loop integrals along other contours as well. New contours that will be useful for our purposes are those whose product encircles simultaneous poles in all four-dimensional components of the loop momentum. Performing the four-dimensional loop-momentum integral over each such contour will yield the residue at the corresponding encircled joint or global pole. The residue extracts \cite{} the terms in the integrand which contain each of the corresponding propagators, removes the denominators, divides by the appropriate Jacobian, and sets the components of the loop momentum to their values at the


J_\alpha \left(a_1 J_1^{-1} {\rm Num}(\ell,\cdots) \Big|_{\Sol_1}
+a_2 J_1^{-1} {\rm Num}(\ell,\cdots) \Big|_{\Sol_2}\right)\,.$$ Using the parametrization (\[OneLoopParametrization\]), we find the following expression for the Levi-Civita symbol we need, $$\begin{aligned}
\varepsilon(\ell,k_1,k_2,k_4) &=&
\alpha_3 s \varepsilon\left(
 {\textstyle \frac{\sand1.{\gamma^\mu}.2}{2\spa1.4\spb4.2}},k_1,k_2,k_4\right)
+\alpha_4 s\varepsilon\left(
 {\textstyle \frac{\sand2.{\gamma^\mu}.1}{2\spa2.4\spb4.1}},k_1,k_2,k_4\right)
\nn\\
&=& s (\alpha_3-\alpha_4)\varepsilon\left(
 {\textstyle \frac{\sand1.{\gamma^\mu}.2}{2\spa1.4\spb4.2}},k_1,k_2,k_4\right)
\,.\end{aligned}$$ The constraint that $U_1 = 0$ on the quadruple cut then implies that, $$-s^{-4} J_\alpha \omega^{-1} \bigl( a_1 + a_2 \bigr) = 0\,.
\label{OneLoopConstraint}$$ so that $a_2 = -a_1$. Higher odd powers of the Levi-Civita tensor lead to the same constraint.

If we evaluate both sides of on the linear combination of contours, we find, $$s^{-4} J_\alpha \sum_{i=1}^2 a_i J_1^{-1} \prod_{j=1}^4 A^\tree_j\Big|_{\Sol_i}
= s^{-4} J_\alpha  c
 \left( a_1 J_1^{-1}\Big|_{\Sol_1} + a_2 J_1^{-1}\Big|_{\Sol_2}\right)\,,$$ where the product is over the tree amplitudes associated to each of the four vertices of the quadruple-cut box integral1)}}\right) = 0\,, \nn \\
(\ell_1 - K_{12})^2 &=& s_{12} \left( (\alpha_1 -1) (\alpha_2 -1) +
\textstyle{\frac{\alpha_3 \alpha_4}{\chi (\chi + 1)}}\right) = 0\,,
\label{HeptacutEquationsI}\\
\ell_2^2 &=& s_{12} \left( \beta_1 \beta_2 + \textstyle{\frac{\beta_3
\beta_4}{\chi
(\chi +1)}} \right)=0\,, \label{eq:q_squared_parametrized} \nn\\
(\ell_2 - k_4)^2 &=& s_{12} \left( \beta_1 (\beta_2 -1) +
\textstyle{\frac{\beta_3 \beta_4}{\chi
(\chi + 1)}}\right)=0\,, \label{eq:q1_squared_parametrized} \nn\\
(\ell_2 - K_{34})^2 &=& s_{12} \left( (\beta_1 -1) (\beta_2 -1) +
\textstyle{\frac{\beta_3 \beta_4}{\chi (\chi + 1)}} \right)=0\,,\nn
\label{eq:q2_squared_parametrized}\end{aligned}$$ where $$\chi \equiv \frac{s_{14}}{s_{12}} \, .$$

We can simplify these equations, obtaining $$\begin{aligned}
\alpha_1 \hspace{-1.5mm}&=&\hspace{-1.5mm} 1 \, , \hspace{5mm}
\alpha_2 \hspace{0.5mm}=\hspace{0.5mm} 0 \, , \hspace{5mm}
\alpha_3 \alpha_4 \hspace{0.5mm}=\hspace{0.5mm} 0\,,
\nn\label{eq:on-shell_values_of_alpha}\\
\beta_1 \hspace{-1.5mm}&=&\hspace{-1.5mm} 0 \, , \hspace{5mm}
\beta_2 \hspace{0.5mm}=\hspace{0.5mm} 1 \, , \hspace{5mm} \beta_3
\beta_4 \hspace{0.5mm}=\hspace{0.5mm} 0\,.
\label{eq:on-shell_values_of_beta}
\label{AlphaBetaEquations}\end{aligned}$$ These equations have four distinct solutions. If we substitute these values into , we find for the last equation, $$\begin{aligned}
0 &=& (\ell_1 + \ell_2)^2 =
 2 \ell_1 \cdot \ell_2


the heptacut equations for the two-loop planar double box.[]{data-label="SixSolutions"}](4-point_DB_kin_S2_alt)

Solution $\Sol_2$, obtained by setting $$\begin{aligned}
\begin{array}{ll}
\alpha_3 = z\,, & \hspace{7mm} \beta_3 = -\chi\,, \\[-5mm]
\alpha_4 = 0\,, & \hspace{7mm} \beta_4 = 0\,.
\end{array}\end{aligned}$$

![The six solutions to the heptacut equations for the two-loop planar double box.[]{data-label="SixSolutions"}](4-point_DB_kin_S3_alt)

Solution $\Sol_3$, obtained by setting

![The six solutions to the heptacut equations for the two-loop planar double box.[]{data-label="SixSolutions"}](4-point_DB_kin_S4_alt)

Solution $\Sol_4$, obtained by setting $$\begin{aligned}
\begin{array}{ll}
\alpha_3 = 0\,, & \hspace{7mm} \beta_3 = 0\,,\nn \\[-5mm]
\alpha_4 = z\,, & \hspace{7mm} \beta_4 = -\chi\,.
\end{array}\end{aligned}$$

![The six solutions to the heptacut equations for the two-loop planar double box.[]{data-label="SixSolutions"}](4-point_DB_kin_S5_alt)

Solution $\Sol_5$, obtained by setting $$\begin{aligned}
\begin{array}{ll}
\alpha_3 = 0\,, & \hspace{7mm} \beta_3 = -(\chi + 1) \frac{z + \chi}{z + \chi + 1}\,, \nn\\[-5mm]
\alpha_4 = z\,, & \hspace{7mm} \beta_4 = 0\,.
\end{array}\end{aligned}$$

![The six solutions to the heptacut equations forthe two-loop planar double box.[]{data-label="SixSolutions"}](4-point_DB_kin_S6_alt)

Solution $\Sol_6$, obtained by setting $$\begin{aligned}
\begin{array}{ll}
\alpha_3 = z\,, & \hspace{7mm}\beta_3 = 0\,, \nn\\[-5mm]
\alpha_4 = 0\,, & \hspace{7mm}
  \beta_4 = -(\chi + 1) \frac{z +\chi}{z + \chi + 1}\,.
\end{array}\end{aligned}$$

The existence of six kinematic solutions can also be understood from holomorphicity considerations of the cuts. When we cut all propagators, each of the six vertices in the double box has three massless momenta attached. We can write these momenta in terms of spinors, $k^\mu = \lambda^\alpha
\sigma_{\alpha \dot{\alpha}}^\mu
\tlambda^{\dot{\alpha}}$. Momentum conservation at each vertex [@WittenTwistorString] then implies that either,

-   the holomorphic spinors $\lambda$ of the momenta are collinear (proportional), $\lambda_a \propto \lambda_b \propto \lambda_c$. We will depict such a vertex using a circled plus ($\oplus$). Such a vertex would allow only an $\overline{\mathrm{MHV}}$ tree


+ 1)}} \right)
\right]\,,\end{aligned}$$ associated with the $\ell_1$ loop. Define $$\left( \hspace{-1mm} \begin{array}{c} g_1(\alpha_1,\alpha_2,\alpha_4)
\\ g_2(\alpha_1,\alpha_2,\alpha_4) \\
g_3(\alpha_1,\alpha_2,\alpha_4) \end{array} \hspace{-1mm} \right)
\hspace{1.5mm}=\hspace{1.5mm} \left(
\begin{array}{c} s_{12} \left( \alpha_1 \alpha_2 +
\textstyle{\frac{\alpha_3
\alpha_4}{\chi (\chi + 1)}} \right) \\
s_{12} \left( (\alpha_1 - 1) \alpha_2 + \textstyle{\frac{\alpha_3
\alpha_4}{\chi (\chi + 1)}} \right) \\
s_{12} \left( (\alpha_1 - 1) (\alpha_2 - 1) +
\textstyle{\frac{\alpha_3 \alpha_4}{\chi (\chi + 1)}} \right)
\end{array} \right) \, .$$ The first Jacobian is then, $$J_1 = \det_{i,j} \frac{\partial g_i}{\partial \alpha_j}
\hspace{1.5mm}=\hspace{1.5mm} s_{12}^3 \det\left(
\begin{array}{ccc}
\alpha_2 & \alpha_1 & \frac{\alpha_3}{\chi (\chi + 1)} \\
\alpha_2 & \alpha_1 -1 & \frac{\alpha_3}{\chi (\chi + 1)} \\
\alpha_2 -1 & \alpha_1 -1 & \frac{\alpha_3}{\chi (\chi + 1)}
\end{array} \right)
 \hspace{1.5mm}=\hspace{1.5mm} -\frac{s_{12}^3}{\chi (\chi + 1)} \alpha_3$$ (As explained in , the Jacobians will appear in the denominator as determinants rather than as absolute values of determinants.) Similarly, the second Jacobianrelative normalization of the contours encircling the two solutions to the on-shell equations.

Similar constraints arise at two loops, though we have a greater variety of Levi-Civita symbols to consider. Denoting the insertion of the function $f(\ell_1,\ell_2)$ in the numerator of the double box by $$\DBox[f(\ell_1,\ell_2)] =
\int {d^{D} \ell_1\over (2\pi)^D} \hspace{0.5mm} {d^{D} \ell_2\over(2\pi)^D}
\hspace{0.7mm} \frac{f(\ell_1,\ell_2)}{\ell_1^2(\ell_1 - k_1)^2
(\ell_1 - K_{12})^2(\ell_1 + \ell_2)^2\ell_2^2
(\ell_2 - k_4)^2(\ell_2 - K_{34})^2} \, ,
\label{DoubleBoxWithInsertion}$$ we must require that the vanishing of the following integrals, $$\begin{aligned}
&& \DBox[\varepsilon(\ell_1,k_2,k_3,k_4)]\,,\quad
\DBox[\varepsilon(\ell_2,k_2,k_3,k_4)]\,,\quad
\DBox[\varepsilon(\ell_1,\ell_2,k_1,k_2)]\,,\quad\nn\\
&&
\DBox[\varepsilon(\ell_1,\ell_2,k_1,k_3)]\,,\quad
\mathrm{and}\quad\DBox[\varepsilon(\ell_1,\ell_2,k_2,k_3)]\,,\quad
\label{LeviCivitaConstraints}\end{aligned}$$ continues to hold for integration over our chosen linear combination of contours. This is the complete set of Levi-Civita symbols that arises during integral reduction, after using momentum conservation.

At two loops, additional reductions are required in order to arrive at a linearly-independent set of basis integrals. These are usually obtained


k_4] +\cdots\,,
\label{eq:IBP-relation_8}\\
\DBox[(\ell_1 \cdot k_4)^2(\ell_2 \cdot k_1)] \hspace{-2mm} &=& -\frac{(1 -
3\epsilon) \chi s_{12}^3}{16(1 - 2\epsilon)} \DBox[1] +
\frac{(3-9\epsilon - 2\epsilon\chi)s_{12}^2}
{8(1-2\epsilon)} \DBox[\ell_1 \cdot k_4] +\cdots\,, \nn\\
\DBox[(\ell_2 \cdot k_1)^3] \hspace{-2mm} &=& \frac{\epsilon \chi
(1-2\chi - 3\epsilon) s_{12}^3}{16 (1-\epsilon)(1 - 2\epsilon)}
\DBox[1] \nn\\
&&\hskip 15mm
+ \frac{\big(2\chi^2 - 3\epsilon (1-2\chi) + \epsilon^2 (9 +
2\chi) \big)s_{12}^2}{8 (1-\epsilon)(1-2\epsilon)} \DBox[\ell_1 \cdot
k_4] +\cdots\,, \nn\\
\DBox[(\ell_1 \cdot k_4)^3] \hspace{-2mm} &=& \frac{\epsilon \chi
(1-2\chi - 3\epsilon) s_{12}^3}{16 (1-\epsilon)(1 - 2\epsilon)}
\DBox[1] \nn\\
&&\hskip 15mm
+ \frac{\big(2\chi^2 - 3\epsilon (1-2\chi) + \epsilon^2 (9 +
2\chi) \big)s_{12}^2}{8 (1-\epsilon)(1-2\epsilon)} \DBox[\ell_1 \cdot
k_4] +\cdots\,, \nn\end{aligned}$$ where the ellipses denote additional integrals with fewer propagators. We must require that these equations (and the other 12 we do not display explicitly) are preserved by the choice of contours. The contour integrals which implement the augmented heptacut will yield vanishing results for the integrals with fewerindicate the winding number. Both representations are for the choice $u=\frac12$ and $v=1$ in . []{data-label="ContourFigure"}](P2_contour.eps "fig:"){width="\textwidth"}\
[(b)]{}

The following values, $$\begin{aligned}
\begin{array}{lll}
a_{1,1} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,1} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,2} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,2} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,3} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,3}\hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,4} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,4} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,5} \hspace{1mm}=\hspace{1mm} 2u - v\,,   \hspace{15mm} &
   a_{2,5} \hspace{1mm}=\hspace{1mm} v\,,  \hspace{15mm} &
   a_{3,5} \hspace{1mm}=\hspace{1mm} 2u\,, \\
a_{1,6} \hspace{1mm}=\hspace{1mm} 2u - v\,,   \hspace{15mm} &
   a_{2,6} \hspace{1mm}=\hspace{1mm} v\,,  \hspace{15mm} &
   a_{3,6} \hspace{1mm}=\hspace{1mm} 2u\,,
\end{array} \label{eq:heptacut_contours_diag_fam_1}\end{aligned}$$


(where $u,v$ are real parameters) solve all the constraint equations (\[Levi-CivitaConstraintFinal\], \[eq:heptacut\_contour\_eq\_6\]), and also set the heptacut of the basis integral $\DBox[\ell_1\cdot k_4]$ to zero, thereby allowing us to extract the coefficient of the first basis integral, $\DBox[1]$. We will call a specific choice of contours weighted by these values $P_1$, leaving the dependence on $u$ and $v$ implicit. A particularly simple solution is given by $u=\frac{1}{2}$ and $v=1$. This choice is illustrated schematically in (a).

Similarly, the following values, $$\begin{aligned}
\begin{array}{lll}
a_{1,1} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,1} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,2} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,2} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,3} \hspace{1mm}=\hspace{1mm} -2u + v\,,  \hspace{15mm} &
   a_{2,3} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,4} \hspace{1mm}=\hspace{1mm} -2u + v\,, \hspace{15mm} &
   a_{2,4} \hspace{1mm}=\hspace{1mm} u\,, & \\
a_{1,5} \hspace{1mm}=\hspace{1mm} 6u - v\,,   \hspace{15mm} &
   a_{2,5} \hspace{1mm}=\hspace{1mm} v\,,  \hspace{15mm} &
   a_{3,5} \hspace{1mm}=\hspace{1mm} 6u\,, \\
a_{1,6} \hspace{1mm}=\hspace{1mm} 6u - v\,,   \hspace{15mm} &
   a_{2,6} \hspace{1mm}=\hspace{1mm} v\,,  \hspace{15mm} &
   a_{3,6} \hspace{1mm}=\hspace{1mm} 6u\,,
\end{array} \label{eq:heptacut_contours_diag_fam_2}\end{aligned}$$ (where again $u,v$ are real parameters) solve all the constraint equations (\[Levi-CivitaConstraintFinal\], \[eq:heptacut\_contour\_eq\_6\]), sets to zero the heptacut of the basis integral $\DBox[1]$, and thereby extracts the coefficient of $\DBox[\ell_1\cdot k_4]$. We will call a specific choice of contours weighted by these values $P_2$, again leaving the dependence on $u$ and $v$ implicit. The choice $u=\frac{1}{2}$ and $v=1$ again gives a particularly simple solution. It is illustrated schematically in


contour in a given calculation.

Rather than using our master formulæ (\[eq:extraction\_formula\_for\_c\_1\]) and (\[eq:extraction\_formula\_for\_c\_2\]), let us evaluate the augmented heptacut integral for a general contour, before imposing the constraint equations. Adding up the contributions from all six solutions, we find $$\begin{aligned}
&& \hspace{-11mm} \sum_{i=1}^6 \oint_{\Gamma_i}
\frac{dz}{z(z+\chi)} \prod_{j=1}^6 A_j^\mathrm{tree}(z) = \nn \\
&& -i s_{12}^2 s_{23} A^\mathrm{tree}_{-+-+} \left[ \sum_{j=1}^6
\frac{a_{1,j} -
a_{2,j}}{\chi} - (4 - \mathcal{N}) \frac{a_{1,6} - a_{3,6} - a_{2,5}}{(\chi + 1)^2} \right. \nonumber \\
&\phantom{=}& \left. \hspace{30mm} + \left( \left( 1 -
\textstyle{\frac{1}{2}} \delta_{\mathcal{N},4} \right)
\frac{\chi^{4 - \mathcal{N}} + 1}{(\chi+1)^{4 - \mathcal{N}}} - 1
\right) \left( \frac{a_{1,3} - a_{2,3}}{\chi}
             + \frac{a_{1,4} - a_{2,4}}{\chi}
             \right) \right] \, . \phantom{aaa}
\label{eq:1-2+3-4+_heptacut_intermediate_step}\end{aligned}$$

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In the present study, we analyzed the expression profile of circRNAs in NSCLC and identified circARHGAP10 to be significantly increased in NSCLC tissues and closely related to the prognosis of NSCLC patients. In addition, we found that circARHGAP10 may function as a sponge of the antioncogene, miR-150-5p, to promote GLUT-1 expression and, consequently, promote NSCLC progression. Therefore, increased circARHGAP10 may serve as a biomarker for predicating prognosis as well


NSCLC PatientsCharacteristicNumbersExpression of circRNA ARHGAP10Low (n = 42)High (n = 50)**Sex**Male502030Female422220**Age**≤60392118\>60532132**TNM Stages**I and II572928III and IV351322**Lymph Node Metastasis**Negative562828Positive361422**Tumor Size**≤3 cm482424\>3 cm441826[^1]

Knockdown of circARHGAP10 Suppressed the Proliferation of NSCLC Cells {#sec2.3}
---------------------------------------------------------------------

To identify the relationship between circARHGAP10 and the proliferation of NSCLC cells, A549 and H1650 cells were used. Detection with qRT-PCR found that the expression of circARHGAP10 was decreased significantly after transfection with small interfering RNA (siRNA) against circARHGAP10 (sicircARHGAP10) in both A549 and H1650 cells compared with the negative control (NC) group ([Figure 3](#fig3){ref-type="fig"}A). This suggests that sicircARHGAP10 cells can be used for further study. Cancer cells metabolically exert the Warburg effect, which is characterized by the preferential consumption of glucose for energy under aerobic conditions rather than mitochondrial oxidative phosphorylation.[@bib13] After analyzing the RNA-seq results, we found that the abnormal expression ofthat miR-150-5p overexpression inhibited cellular activity and proliferation in both A549 and H1650 cells. GLUT1 overexpression rescued the cellular activity and proliferation following miR-150-5p overexpression in both A549 and H1650 cells. Wound-healing assays found that miR-150-5p overexpression inhibited the closure of scratch wounds, whereas GLUT1 overexpression promoted the closure of scratch wounds following miR-150-5p overexpression ([Figures 6](#fig6){ref-type="fig"}K--6M). The Transwell assays also showed that GLUT1 overexpression reversed miR-150-5p overexpression and induced the inhibition of both A549 and H1650 cell migration ([Figures 6](#fig6){ref-type="fig"}N--6P). These findings suggest that the overexpression of GLUT1 reversed the inhibitory effect of miR-150-5p on cellular proliferation and metastasis *in vitro*.

Discussion {#sec3}
==========

The role of circRNAs in carcinogenesis and cancer progression has attracted recent attention; however, the role and function of circRNAs in NSCLC remain unclear. Therefore, in the


bioinformatics analysis found that GLUT1 was the target of miR-150-5p, which was confirmed with a luciferase reporter assay. The *in vitro* study found that miR-150-5p overexpression suppressed NSCLC cell proliferation and metastasis. GLUT1 overexpression rescued NSCLC cell proliferation and metastasis following miR-150-5p upregulation, because heterologous GLUT1 has no 3′ UTR. Therefore, miR-150-5p cannot interact with the 3′ UTR of GLUT1 and silence it at the mRNA level.

Conclusions {#sec3.1}
-----------

In summary, our study first revealed that circARHGAP10 is increased in both NSCLC patient and cell lines, and this upregulation may be associated with aggressive NSCLC phenotypes. Additionally, circARHGAP10 silencing suppressed NSCLC proliferation and metastasis in both *in vitro* and *in vivo* experiments. We also found that the downregulation of circARHGAP10 suppressed the proliferation and migration in NSCLC by targeting the miR-150-5p/GLUT1 axis. Inthe TargetScan website at <http://www.targetscan.org/>. The relationship between ARHGAP10 and the prognoses in NSCLC patients was predicted using the GEPIA (Gene Expression Profiling Interactive Analysis) website at <http://gepia.cancer-pku.cn/>.

Total RNA Isolation and qRT-PCR {#sec4.6}
-------------------------------

Total RNA was isolated from the tumor tissues or cells using TRIzol Reagent (Invitrogen, Carlsbad, CA, USA) following the manufacturer's protocol. The purity and concentration of the RNA samples were examined spectrophotometrically by measuring the absorbance at 260 nm, 280 nm, and 230 nm using the NanoDrop ND-1000 (Thermo Fisher Scientific, Wilmington, DE, USA). Specifically, optical density (OD)260/OD280 ratios between 1.8 and 2.1 were deemed acceptable, and OD260/OD230 ratios greater than 1.8 were deemed acceptable.

RNA (1 μg) was reverse transcribed into cDNA using SuperScript II Reverse Transcriptase (Invitrogen, Thermo Fisher Scientific). Then qRT-PCR was performed using an AB7300 thermo-recycler (Applied


propagation direction. The term (ωt-K·R) has been used extensively for propagation phase. K represents a directional (moving) surface and R a directional propagation displacement. Therefore K is a “wavefront” mathematically. We will be using K-space as wavefront domain or wavefront space.I have a 40HP Mariner 6E9 engine and it runs very well up until high RPM'S at WOT and bogs down, I observe that when I put it into gear it moves a bit, the linkage to shoves the magneto linkage moves up a small bit( fully advanced in youtube video below)...

Johnson Electramatic starter/bracket removal

Johnson/Evinrude service manuals talk about removing 1 large bolt above and starboard side of the carb, and 3 bolts OR NUTS to remove the starter bracket. None mention the two smaller bolts in the lower support bracket... and that leads to my question....

Mid 90's Mariner Magnum 40hp Trim Relay Harness question

I'm getting (I think a 96?) Mariner Magnum 40hp outboard that's just been rebuilt and is in great running condition with a pontoon I'm


(O18A1) (95 nm) ([Table 1](#viruses-10-00289-t001){ref-type="table"}).

In vitro DNA ejection of HK620 could be observed in fluorescence using *E. coli* DSM10809 LPS (O18A) as a receptor, although with a lower efficiency than found for the host LPS ([Figure 5](#viruses-10-00289-f005){ref-type="fig"}A). By contrast, LPS preparations of *E. coli* IHE3042 (O18A1) did not provoke DNA release. It is important to note here that HK620 was unable to successfully infect both *E. coli* DSM10809 (O18A) and *E. coli* IHE3042 (O18A1) strains tested and only formed plaques on its host strain *E. coli* H TD2158 (O18A1). However, when plaque formation on this strain was monitored after incubation with LPS from the two non-host strains, *E. coli* DSM10809 LPS (O18A) was found to significantly (α \< 0.05) decrease HK620 pfu to 16% of the initial valuevivo. Although they cannot show how phage proteins and genetic material enter the cytosol of a living bacterial cell, they provide a reductionist approach to the mechanisms in the bacteriophage infection machine. In vivo, to transport its DNA over all parts of the gram-negative cell envelope, P22 particles extend their tails to form tubular structures, as found in other gram-negative-specific phages \[[@B45-viruses-10-00289],[@B46-viruses-10-00289],[@B47-viruses-10-00289]\]. These extensions at the tip of the tail are most probably formed by P22 ejection proteins that must leave the particle at an early time point after opening. Accordingly, initial LPS contacts leading to rearrangements in the tail and to particle opening are crucial to start genome delivery.

We monitored kinetics of in vitro HK620 particle opening with a DNA-sensitive fluorescence assay. The DNA egress can be


the phage tail apparatus.

In principle, the thermal barriers that we observed for the HK620 DNA ejection process in vitro could have two origins: First, a temperature-dependent destabilization of the tail complex leading to an ejection-competent particle at a permissive temperature. Recently, it was shown for the podovirus T7 that tapping the capsid wall with an oscillating atomic force microscope cantilever could trigger rapid DNA ejection via the portal, illustrating that a conformational switch can be mechanically activated by external forces \[[@B49-viruses-10-00289]\]. Second, temperature-dependent structural transitions might also be present in the LPS aggregates that act as an in vitro receptor. Here, rising the temperature may influence the biophysical properties of the LPS glycolipid preparation, for example, enhanced dynamics and disorder of LPS aggregate packing. In the case ofejection from phage HK620 (6.7 × 10^9^ pfu) triggered by 16.7 μg/mL *E. coli* H TD2158 (O18A1) LPS in the presence of the fluorescent DNA-binding dye Yo-Pro at 45 °C (black circles). Ejected DNA could be digested by adding DNase after 6000 s (white circles). Controls contained an *E. coli* H TD2158 (O18A1) lipid A preparation (pink circles), an O-antigen polysaccharide preparation lacking lipid A (grey triangles) or a mixture of both (blue circles). Standard deviations were obtained from three independent experiments and do not exceed 5% of the total fluorescence signal. (**E**) DNA ejection of HK620 at different temperatures (same conditions as in **D**).](viruses-10-00289-g001){#viruses-10-00289-f001}

![Phage HK620 in vivo infection assays. (**A**) In vivo plaque forming assay after incubation of 4.5 × 10^3^ pfu mL^−1^ HK620 particles with 25


said they were satisfied: 73 percent of those enrolled in a private plan and 84 percent of those enrolled in Medicaid.

There was a minimal difference between the previously uninsured and the previously insured: 79 percent of the former were satisfied and 77 percent of the latter were, according to the survey by the group, which is generally supportive of Obamacare.

Those surveyed also reported being better off: 58 percent said that they were better off now than they were before, while 9 percent said they were worse off. And 81 percent said that they were optimistic that their new coverage would help them get the health care they need.

Some of the survey's broader findings, on the overall drop in the number of uninsured and the percentage of Obamacare enrolleeshow to live? Go fvck yourself little boy. You're likely still living with mommy & daddy. Pu$$y.

azjetfan, on 02 July 2014 - 03:36 PM, said:

There are a few things I have realized about Mr. Jet over a few topics.

1) He is a racist. By constantly using race as a battling tool.
2) He is an extreme Liberal. If you are on either extreme you are probabaly more wrong than right.
3) He is one of those people who will never admit fault, error or defeat.
4)His life sucks and he takes it out on people who don't share in his views.

Dylan Scott is a left wing liberal. His writings and surveys are about as reliable as Sean Hannity's. The commonwealth president is none other than David Blumenthal who was senior health


bankrupt the country. But for some reason you are ok with it since it's a black president.

I didn't even support Obama before and early in the 2008 Democratic primaries. But nice try. I guess with your logic if Allen West ever becomes president I'll support him become we black guys always agree and stick together. And I'm the racist one.

Quote

If this was Bush you would be crucifying him.

Yep I sure did. When he squandered the surplus we had in 2001 and blew up the deficit during his 8 years, I sure did criticize him. I'm one of those people that doesn't believe the world began on January 20, 2009.

Quote

Your Single payer system idea may have legs but that's not what your biased article was about. More importantly that'swho created this "financial hell". But I guess you guys are too busy worshiping Saint Reagan to remember any of that.

I did not support the ACA 100% in 2009 when it was still a bill and I still think it's a flawed system (no surprise since it is mostly a Republican idea). But I realize the ACA is better than the "you're shit out of luck if you get sick" system we had before 2010. The ACA is just a step closer to single payer which would be better (not perfect but much better). Maybe if the Republicans supported and passed a single payer health care bill we could get rid of Obamacare. They'd get many Democrats in congress to vote for it if they did and it


Braun. Kerry, Edwards, and Gephardt are all white BTW. So, so much for me only voting for and supporting candidates because they're black.

Quote

That's why I said if Bush said and did all the same things you would be all over him.

What didn't I criticize Bush about. I criticized him for cutting taxes for his rich buddies while sending Americans kids off to fight and die in not one but two wars. The second of which was a totally unnecessary war. I criticized his borrow and spend policies. I criticized him over squandering the surplus Clinton left him with. I criticized him over trying to privatize Social Security. I criticized him over his policy on federal funding of stem cell research. I criticized him for not bringing Osama binor defeat.
4)His life sucks and he takes it out on people who don't share in his views.

What difference does it make what I say? You're too far in the Breitbart woods to understand logic and reason anyway. If President Obama said that the sun is hot you'd just say he was a liar and that he was born in Kenya. I mean I can't have discussion with you when you only hear what you want to hear. So now like with the other resident birther on this board (gmany), I just have to f*** with you for my own amusement. You voted for Bush in 04 and all your "the sky is falling" talk now about the debt is disingenuous.

The difference between you and me is that I


part-time workers to get or keep them under a 30-hour-a-week limit. The Washington Post, for instance, wrote about the state of Virginia implementing such a cap on the hours of part-timers, like adjunct faculty at Northern Virginia Community College. And other colleges have instituted such limits, according to press reports. These employers have not indicated in the news reports whether they would be hiring additional workers, or increasing the hours of others, to fill in the gaps.
“ObamaCare by the Numbers,” Aug. 2

Claim: The law is a job-killer.
FactCheck.org says: Overblown.
It’s true nonpartisan economic analyses have estimated a “small” loss of mainly low-wage jobs because of the law. But as one expert told us, there hasn’t been much analysis of this impact of the law because, he believes, economists think2011

Premiums
Claim: Premiums are going up because of the law. Premiums are going down because of the law.
FactCheck.org says: It depends.
Politicians have been making these claims since before the law was passed — it was the first item on our list of whoppers back in 2010. Both sides have a penchant for misrepresenting studies on the matter to support their point. Our short answer — “it depends” — may be unsatisfactory to readers, but whether you’ll pay more or less than you would have without the law depends on your circumstances.
Are you uninsured and have a preexisting condition? You’ll likely pay less than you would have otherwise. Are you uninsured but young and healthy? You’ll likely pay more (without accounting for any subsidies you may receive). Are you insured


Premium Spin,” April 5
” ‘Obamacare’ to cost $20,000 a Family?” March 1

Claim: All of the uninsured will pay less on the exchanges than they could now on the individual market, even without federal subsidies.
FactCheck.org says: False.
President Obama made this claim at an Aug. 9 press conference, saying that beginning Oct. 1, the 15 percent of the population that’s uninsured would be able to “sign up for affordable quality health insurance at a significantly cheaper rate than what they can get right now on the individual market.” Obama went on to emphasize that that was before including federal subsidies. “And if even with lower premiums they still can’t afford it, we’re going to be able to provide them with a tax credit to help them buy it,” he added.
But508.) Left open by the majority here is the continuing vitality of the majority opinion in Tyrell J., which upheld an officer's warrantless search of a minor based upon the minor's probation search condition of which the officer conducting the search was unaware.
I would draw no distinction between the warrantless search of an adult parolee and the warrantless search of a juvenile probationer. As to each, would apply the same analysis: Neither search can later be justified by information such as the search condition in this case that was unknown to the searching officer.

II
I have an additional observation about the majority's analysis. As I noted at the outset, the purpose of the Fourth Amendment is to safeguard the right to be free from unreasonable searches and seizures. (See


therefore would affirm McDaniel's conviction.

I.
The Fourth Amendment guarantees "[t]he right of the people to be secure in their persons, houses, papers and effects, against unreasonable searches and seizures" and provides that "no warrants shall issue, but upon probable cause, supported by oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized." (U.S. Const., Amend. IV.)
The rules and regulations governing the California parole system authorize any law enforcement officer to search a parolee and his or her residence at any time without a warrant. (Pen.Code, § 3052; Cal. Code Reg., tit. 15, § 2511, subd. (b)(4).) "The state has a duty not only to assess the efficacy of its rehabilitative efforts [with respect to parolees] but to protect the public,search term that put him on notice that any law enforcement officer might search his person and his residence at any time without a warrant. While in their apartment, defendants McDaniel and Sanders engaged in a loud fight that led neighbors to call the police. When police officers arrived and knocked on the door, someone deadbolted the door, refusing them entry. Eventually Sanders opened the door and allowed the officers inside. At that point, the officers saw McDaniel hide something metallic behind a couch cushion. The officers also observed that Sanders appeared to have been in a physical altercation, with a fresh abrasion on her face. Sanders and McDaniel soon became belligerent and combative with the officers. McDaniel demanded that they leave the apartment, even though his parolee


terms for parolees "is triggered by [the parolee's] own conduct. The existence of this triggering eventthe crime which results in conviction ...creates the compelling need for government intervention and diminishes any reasonable expectation of privacy." (Ibid.)
The high court similarly recognizes that a state's "interest in apprehending violators of the criminal law, thereby protecting potential victims of criminal enterprise, may therefore justifiably focus on probationers in a way that it does not on the ordinary citizen." (Knights, supra, 534 U.S. at p. 121, 122 S.Ct. 587, italics added.) A parolee such as McDaniel, however, presents a much more serious risk to society than a probationer, in that a parolee is not placed on probation but is sent to *651 prison, either because of the seriousness of his or heract belligerently toward the officers, who handcuff them. Rather than conducting a protective sweep, the officers immediately call the police department. They are told, erroneously, that neither disputant is a probationer, but that Y is a parolee. Relying on this incorrect information, the officers search the apartment unit and find illegal drugs, which they seize, in Y's open closet. A day later, the officers discover that, in fact, Y's parole had long since expired, but he currently is on probation subject to a search condition. Under these circumstances, the officers' good faith reliance on the outdated and erroneous parole status information would not validate the search of Y's closet (People v. Willis (2002) 28 Cal.4th 22, 120 Cal. *653 Rptr.2d 105, 46 P.3d 898), and according to the


v. Cook (1978) 22 Cal.3d 67, 82-83, 148 Cal.Rptr. 605, 583 P.2d 130; see also In re Lance W. (1985) 37 Cal.3d 873, 882-883, 210 Cal.Rptr. 631, 694 P.2d 744; Dyas v. Superior Court (1974) 11 Cal.3d 628, 632-633, 114 Cal.Rptr. 114, 522 P.2d 674; but see People v. Miller (1972) 7 Cal.3d 219, 226, 101 Cal.Rptr. 860, 496 P.2d 1228; Mann v. Superior Court (1970) 3 Cal.3d 1, 8, 88 Cal.Rptr. 380, 472 P.2d 468.
[1]  The majority expresses no view regarding this aspect of the Court of Appeal's analysis (maj. opn., ante, 2 Cal.Rptr.3d at p. 647, fn. 2, 73 P.3d at p. 500, fn. 2), and neither do I.
how these protests can be policed,” Scott said, citing a large rally and counter-protest in that city last weekend.

There were less than three dozen arrests as about 50 extreme-right protesters saw their self-described “free speech” rally dwarfed by a massive turnout of about 40,000 counter-protesters. Police there officially ended the rally and escorted conservative rally members to protect them from the massive crowd.

Scott’s boss, Mayor Ed Lee, already has denounced the San Francisco rally as designed to “incite hate, bigotry and violence.”

“They will have their rally on federal land because the U.S. Constitution provides all of us the right to freedom of expression,” he said. “But as mayor of this city, I say: Any message of hate is not welcome.”


as modulators of voltage-gated channels \[[@CR12]\]. FGFs function in a wide variety of developmental processes ranging from axis patterning in embryos \[[@CR13]\] to induction and maintenance of cell lineages \[[@CR14]\]. In humans, the functional diversity of FGFs arises from the combinations of 22 FGFs and four FGF receptors (FGFRs) \[[@CR15]\]. In *Drosophila melanogaster*, there are three FGF ligands, *Branchless* (*Bnl*), *Pyramus* (*Pyr*) and *Thisbe* (*Ths)* \[[@CR16], [@CR17]\], and two FGFRs, *Heartless* (*Htl*) and *Breathless* (*Btl*) \[[@CR18]\]. Binding of FGF to its receptor promotes dimerization of FGFRs, initiating a molecular cascade that activates phosphatidylinositol 3-kinase-Protein Kinase B (PIP3-Akt) and Ras-mitogen-activated protein kinase (MAPK) signaling pathways \[[@CR19], [@CR20]\]. The FGFR signaling pathways are highly conserved in metazoan organisms \[[@CR21]\], indicating that FGF and FGFR signaling might function similarly in thelaser-scanning confocal microscope FV1000, with a 40× objective (N.A. 1.3). Transmitted light images were acquired and used to evaluate dissection quality and to measure thoracic ganglia width. Only images without CNS damage or surface occlusions were included for data analysis. Maximal intensity projections were stacked from optical sections and adjusted for contrast and brightness if required. Measurements of axonal branch length and branch number were performed blind to genotype. Custom-written software in MATLAB was used to perform the quantitative image analysis.

Behavioral assay and analysis {#Sec7}
-----------------------------

The behavioral assay and analysis was performed as previously described \[[@CR26]\]. The *455-Gal4* driver was used to selectively express *UAS-dsRNA* in the scutellum to ensure that RNA interference did not perturb the postsynaptic neural circuitry. Two-day old female flies were decapitated and placed in


The present invention relates in general to ultrasonic aspirators and in particular to an ultrasonic aspirator intended for use in surgical operations for removing tissue. More specifically, the ultrasonic aspirator is of the kind including an integrally implemented amplitude transformer with a tip intended to be brought into contact with the tissue, and to serve as a kind of knife with the ability to remove tissue with precision, the tissue being comminuted by the ultrasonic effect into fragments which are sucked away, aspirated, through the elongate tip portion of the ultrasonic aspirator, this portion being the one providing the removal mentioned. Somewhat improperly the ultrasonic aspirator is hereinafter called an ultrasonic knife. A transducer working as a vibrator is mechanically connected to the amplitude transformer and causes thetip portion to oscillate longitudinally. A frequency generator feeds electrical energy of ultrasonic frequency to the transducer unit, which converts this energy into a mechanical longitudinal oscillation, the amplitude of which is reinforced by the amplitude transformer so that the tip portion executes the longitudinal oscillation with great oscillation amplitude.
Ultrasonic knives of the kind mentioned above are known from such as U.S. Pat. Nos. 3,526,219, 4,063,557, 4,223,676, 4,525,115 and EP-A- 0 139 753.
In order that an ultrasonic knife shall function clinically satisfactorily it is an absolute requirement that the tip portion executes a pure longitudinal oscillation movement. Oscillation in the transverse direction must not occur, since such movement would be directly destructive for operations in sensitive areas. Every osciallating mass, and particularly a complicated ultrasonic transducer, has a


plurality of resonance frequencies at which oscillation amplitudes in the transverse and/or longitudinal direction are possible. The resonance frequencies change when the resonance conditions of the oscillating body are modified, e.g. when it is immersed in water or comes into contact with tissue. What is particularly important for an ultrasonic knife is that when the knife is in operation, and thereby changes its resonance frequency, the frequency generator must change the frequency of the electrical energy supplied to the knife so that the knife continues to oscillate and thereby to remove material. It is known to use frequency control circuits for this purpose, and voltage controlled oscillators in particular. It is then important that the voltage controlled oscillator locks on to the resonance frequency pertaining to the longitudinal-3 - (23 - -1)
-18
Evaluate -38 + (7 - -24) + 7 + (-74 - -1) + 7.
-66
What is 17 + (1 + -16 - 1) - (8 + -2)?
-5
-75 + 53 + -64 - -90
4
Calculate -26 + (-85 - -23) + 97.
9
What is the value of -19 - -3 - ((-24 - -24) + (-4 - 9) + 7)?
-10
Evaluate -31 + (-127 - (-103 + -3)).
-52
Evaluate 30 + 3 - (-1 + 16 - 9).
27
41 + (42 - (-21 + 15))
89
Calculate (75 - -87) + -51 + -60.
51
What is the value of -6 + 18 + 4 + (98 - (3 + -12))?
123
62 - (-101 - (-57 + -16))
90
Calculate (-53 - -66) + 0 + 43 + (-5 - -2) + -3.
50
(-6 - -53) + (8 -


X is sulfur, simply replace reagent 1h with an aromatic thiol, such as 3-aminothiophenol and carry out the remaining steps of the Scheme.
To produce other substitutions at R3 or R4, some of the products of Scheme 1 may be used as shown in Scheme 2. For example, to produce a compound where R3 is hydrogen and R4 is CH3C(O)xe2x80x94, the five-membered ring intermediate 1e may be treated with a base, such as barium hydroxide, at reflux in ethanol to give the free amine 2a. The amine can be subsequently treated with an acid anhydride, such as trifluoroacetic anhydride, to give 2b. This intermediate may be carried through the remaining steps of Scheme 1 to
produce the desired compound ld.
The products of Scheme 1 may be used toproduce other compounds of the invention as shown in Scheme 3. For example, to produce compounds of type le, treat compound lc with a phenyl isocyanate preferably at room temperature. To produce compounds of type lf, lc may be treated preferably at room temperature with acid chloride derivatives such as benzoyl chloride. In order to produce thiols lg, compounds of type lc may be treated with isothiocyanates, such as phenylisothiocyanate preferably at room temperature. If pure enantiomers are desired, they may be obtained by chromatography of the reactant lc or the products.
Scheme 4 makes use of the intermediate of Scheme 1. Treatment of the aldehyde, 1f, with a nitroaniline derivative 4a (a known compound), and NaCNBH3 preferably at room temperature will give the coupled intermediate 4b. This


Q:

Servlet chaining with “jquery-1.8.2.min.js” and “jquery.mobile-1.2.0.min.js” does not work?

I have written code in which a request to ServletA will call ServletB which in turn redirect the user to an external page (i.e. PayPal page).
The code works fine and redirects to the correct page until included the jquery and jquery.mobile to the initial jsp page.

  Call to ServletA

On debugging I know that I reach ServletB but for some reason I do not get redirected to the external link. The page only hangs with ‘Error loading page’ briefly appearing.

A:

By default JQM will request all pages via AJAX. When doing so, JQM is loading the page and grabs what is inside the first

.
If the servlet page is notInvestors wait to see if hospitals held admission volumes in Q2

Investors will be watching beginning this week to see if hospitals maintained admission and outpatient volumes during the second quarter.

The start of second-quarter earnings releases will see publicly traded hospitals trying to match fairly tough comparable numbers from last year. There was also one less weekday in this year's second quarter to provide services.

"We'll be looking for them to reiterate (earnings) guidance for the year," said Brian Tanquilut, senior vice president of healthcare equity research at investment firm Jefferies & Co.

Giant HCA kicks off the hospital earnings season on July 25 followed over the next several days by Tenet Healthcare Corp., Community Health Systems, LifePoint Health and Universal Health Services.

Tanquilut said hospitals and their physician service vendors such


as Envision Healthcare are coming to grips with "a new normal" of slowing admissions growth.

Hospitalizations are rising at 1% to 2% annually today vs. 3% to 4% in the years following the Affordable Care Act and related state Medicaid expansions.

Growth in the ranks of the newly insured from the ACA have flattened and nearly full national employment means few new people are getting employer-sponsored insurance to juice volumes, Tanquilut said, adding that dynamic also could begin to affect outpatient volumes.  Envision recently throttled back guidance for growth in same-store ambulatory surgery volumes from the mid-to-high single digits to the low-to-mid single digits, Tanquilut said.

Despite concerns about a repeal of the ACA, investors in hospital stocks have stuck with them given the ability of management to navigate theflow of cooling air which carries away excess calories has become necessary. In conventional installations, air is collected in the premises on which the oven is installed, using one or more fans. Once thermal exchange has been achieved, this air is evacuated within the premises at the top part of the oven.
The search for ever-increasing rates of production, the blowing of bottles or containers having increasingly complex shapes, and reducing the weight of the preforms while preserving, and indeed enhancing, the technical performance of the finished articles, require a distribution of material in the final product which is both precise and accurately repeated during the entire production run. These requirements make it necessary to control completely the thermal treatment of the preforms, thereby requiring precise adjustments regulating the


two meetings a week he was required to attend were cursory.

There have been reports of probation officers conducting checks over the phone, rather than face to face, and holding meetings in public spaces to discuss intimate issues with offenders. There is also the issue of levels of experience among probation officers. As in the prison service, the numbers of experienced officers has declined.

Johnson has launched a review of licensing conditions for all convicted terrorists released from prison but individuals subject to Mappa plans are already supposed to be reviewed once a month.

Harry Fletcher, the former head of the National Association of Probation Officers (Napo), has questioned why it took such a tragic event for these licences to be reviewed when a Mappa plan was in place and saysand graphics tend to have different main image styles, so we’ll cover the two product types separately. First up, let’s talk about fonts. There have been many, many times I’ve seen a font in the marketplace where the main image is just a solid color—usually a muted and unsaturated color—with the font written out in a different solid color. While in a perfect world the font should speak for itself, customers like to see something with a bit more flair.

Here’s the same text in two different images. By moving the text so it’s left-justified, and putting it over a fairly simple image of a basket of flowers, we’ve created an image with interesting irregularities, and a pop of color to catch the eye, while still showing off the


zoom in on the baseline of this lowercase y. The WinDescent line is just under the baseline, and cuts through the descender of the y. That means that users of certain programs like Microsoft Word will have the bottom of that y cut off. If your font isn’t exceptionally tall or long, there’s no reason to not set your WinDescent below the longest letters, and your WinAscent above the tallest letters, so that your font is accessible and ready for immediate use in all programs. There are a ton of fonts out there with the WinDescent set to zero, so it’s at the same height as the baseline, and it chops off anything below the baseline in Word, PowerPoint, Publisher, and a number of other programs. Take theTest-retest reproducibility of the relative dose response for vitamin A status in Guatemalan adults: issues of diagnostic specificity.
The relative dose response (RDR) test was examined with regard to specificity and reproducibility in subjects with adequate dietary intake and normal liver reserves of vitamin A. Twelve subjects were administered an RDR test four times over 22 d, including one placebo test in which the oral dose of vitamin A was omitted. Additionally, static measures of retinol, tocopherol, retinol binding protein (RBP) and prealbumin (PAL) were taken to determine the intra- and inter-individual coefficient of variation for these blood constituents. Intra-individual coefficients of variation were as follows: retinol, 8.8%; RBP, 11.5%; PAL, 7.6%; and alpha-tocopherol, 8.8%. The mean RDR in vitamin A-replete subjects was 1.2% and ranged from approximately -25%


various statements contained within this website have not been evaluated by the MOH, BMA or the FDA and, as such, these products are not intended to treat, cure, mitigate or prevent any disease or ailment."Whoa." "Sorry, sorry." "That's my son." " Oh, thank God!" " This your Daddy?" " Yes." "(clicking tongue)" " Get your ass off my bus!" " Thank you." " WHAT ARE YOU DOING?" "WHERE WERE YOU GOING?" " Queens." " It's too dangerous to travel alone, Zack." "You know that." " I want Mom to see me again." "I think she misses me." " (Dutch):" "Holy shit!" "What?" "(sighing)" " Who put this up?" " Is that your friend from the convenience store?" "The one that stole all your money, huh?" " Yeah, who would put this up?" " Hey, you gave your pop a scare." "You at least carrying?" " You're coming to the lab with me tomorrow." " What for?" " You'll see." " Hey, Professor,


1874 in association football

The following are the association football events of the year 1874 throughout the world.

Events
February 10 - The Football Association authorized referees to send off players. Before, the squad captains decided sending off.
March 7 - At Hamilton Crescent in Glasgow, Scotland won 2-1 against England, (attendance: 7,000).
March 14 - Third FA Cup is won 2-0 by Oxford University against Royal Engineers in a final played at the Kennington Oval in London (attendance: 2,000).
March 21 - First Scottish Cup is won 2-0 by Queen's Park against Clydesdale (attendance at Hampden Park: 3,000).
The Football Association makes a rule change so that teams change ends at half time.
The first shin pads are introduced.

Clubs founded in 1874

Aston Villa
Bishop's Stortford
Bolton Wanderers
Grantham Town
Macclesfield Town
Northwich Victoria

Greenock Morton
Hamilton Academical
Heart of Midlothian

Domestic cups

Births
April 20: Stevethe onset of foraging and show clear evidence of improved learning of panorama cues after these learning walks ([@B24], [@B26]). Learning walks appear to be mediated by the environment, as species inhabiting landmark-rich environments (*Cataglyphis aenescens* and *Cataglyphis noda*) will occasionally 'pirouette' and turn back to the nest, likely learning panorama cues ([@B25]). These pirouettes are observed in some barren-habitat species (*Ocymyrmex robustior*, [@B48]) but not in the widely studied *C. fortis*. Conversely, *C. fortis* foragers walk in loops without stopping, even when landmark cues are artificially present ([@B25]). Interestingly, the absence of pirouetting does not prevent this species from learning these cues during these walks ([@B24]). Species-specific differences in terrestrial cue learning during these walks, as well as those of species outside of *Cataglyphis* and *Ocymyrmex* remain


learn associations using local olfactory, magnetic, and vibrational cues. *Cataglyphis noda* will search at locations with locally distinct magnetic, vibrational, and olfactory signatures when these had previously been paired with the nest entrance ([@B8]). Additionally, olfactory cues can be learned in association with locations beyond the nest site as part of the foraging route. *Cataglyphis fortis* foragers have been shown to learn odor landmarks along their foraging route after training ([@B7]). Recent work in the *Cataglyphis* genus is unveiling that the role of olfactory cues has been understudied as a navigational cue set for both nest and food locations ([@B8],[@B9], [@B10], [@B6], [@B7]).

Integration of Navigational Information
=======================================

Directional Cue Integration
---------------------------

On featureless saltpans, without visual guidance cues, *C. fortis* foragers use path integration not only to return home, but also tobe more certain than that from visual memory. The merging of directional information from the two systems has been shown to happen in an optimally weighted manner, taking this relative certainty into account ([@B80]).

Cue Integration During Learning
-------------------------------

The role of learning terrestrial visual cues in such conflict situations has also been explored in more detail in *M. bagoti* ([@B27]). Foragers restricted to the nest site could not extrapolate visual panorama information to a local (8 m) site. While one exposure to this new panorama was sufficient for successful homing, it did not override a conflicting vector direction. Repeated exposure to the new panorama increased the weighting of these cues, eventually overriding vector information. Interestingly, this pattern of cue choice appears to be dynamic, as terrestrial cues were increasingly discounted


heading, as the direction of POL angles depends on the azimuthal position of the sun. In ants, the neuroanatomy of the CX and its subcompartments is nearly identical and likely functions similarly ([@B37]).

![Overview of the main neural structures in the ant brain. **(A)** 3-D reconstruction of an entire *Cataglyphis noda* brain in frontal view, based on confocal laser scanning microscope images. The mushroom bodies (MBs, paired neuropils) are dorsally located (shown in pink and purple), and the central complex (CX, a central neuropil) is located at the midline of the brain (shades of blue). The optic lobes (OLs) with their subcompartments medulla (ME) and lobula (LO) extend laterally toward the compound eyes (not shown), and the antennal lobes (ALs) ventrally toward the antennae (not shown). Adapted from [@B37].Q:

Eureka server not accessible for traditional war deployment In Docker

Eureka boot gradle project here. Works fine when I run bootRun, Eureka binds to port 8080 on localhost, accessible from browser, everyone happy. When started as a Docker container, the app seems to start alright without any exceptions but I cannot access the Eureka console from browser on the port 8080. I get a 404.
I know that there are several examples of Eureka on Docker but none using gradle and traditional deployment.
Command I use to start a container: docker run -it -p 8080:8080 -e DOCKER_HOST="$(echo $DOCKER_HOST | grep -Eo '([0-9]{1,3}\.){3}[0-9]{1,3}')" xxx
Docker engine 1.9 with Docker Machine on a Mac.
Log Snippet:
Adding replica node: http://192.168.99.107:8080/eureka/
2015-12-26 03:35:42.959  INFO 7 --- [ost-startStop-1] n.a.javaee.discovery.DiscoveryServer     : Started DiscoveryServer in


[Intermittent ventilatory assistance with a mouthpiece (volumetric type respirator): optical technic of rehabilitation].
The authors described an optical technique enabling patients with chronic respiratory insuffiency, at first to get used to assisted ventilation, then to control it, to obtain an active ventilation operated by machine corresponding to a particular shape of the pressure curve and to the lesser haemodynamic repercussion.Metal Gear Solid V Ground Zeroes PC Technical Review

Company: Konami

Author: Sean Ridgeley

Editor: Sean Ridgeley

Date: December 18th, 2014

Introduction, setup, requirements

Metal Gear Solid V: Ground Zeroes (MGS V: GZ) makes its debut on PC today, marking the third Windows release for the stealth series, following the original Metal Gear Solid in 2000 and the more recent Metal Gear Rising Revengeance (our tech review on that here). GZ is the prologue to the forthcoming release of MGS V: Phantom Pain, and serves as a great tech showcase for Konami's impressive Fox engine.

If you're curious on how the game fares in terms of PC features and performance, read on for a light technical analysis.

Test Setup

OS: Windows 8.1 64-bit

Processor: Intel Core i5 3570K 3.4GHz (Stock)

Memory: Corsair XMS3 8GB DDR3-1600 (Stock)

Storage: Western Digital Caviar


BP’s spokesman on the Gulf of Mexico crisis is Andrew Gowers, 53, formerly editor of the Financial Times, who departed ‘the pink’un’ in 2005 over ‘strategic differences’ with the management.

After Gowers joined Lehman Brothers as head of communications the U.S. merchant bank duly collapsed in 2008.

He once embarrassed himself at a Paris dinner after leaving to take a call on his mobile, forgetting he was wearing a microphone.

Fellow diners heard him call the event ‘a complete waste of time… the same old c**p… the usual old b******s.’

Bearded Andrew seems to be a walking disaster zone.

New role: Lindsay Lohan is starring in a Deep Throat remake

The hugely successful 1972 porn flick Deep Throat is to be the subject of a new movie starring the much rehabilitated Hollywood actress Lindsayhires a woman pastor would be on the other side of a picket fence. I can affirm them as Christians. I could work with them on a community food bank. I would have less cooperation with them than I would, say, a church that baptizes babies, but not by much. So I began to think, since it seems pretty easy for me to define where I would place the picket fences, I wanted to see if I could clearly define where I place my brick walls. I think the following 3 questions sum up how I would decide who is on the outside of the brick wall doctrinally.

Who is God?

For me to consider someone a Christian, I would want to know first of all who they think God


affirm His literal, physical resurrection. They would have to acknowledge the miracles He performed as well. They would have to affirm that His death on the cross paid the price for sins and it is only by a person consciously trusting in Him and repenting of those sins that they can be saved. I would also consider it foundational that they acknowledge His ascension to the right hand of God the Father in heaven. In short, they would have to acknowledge Him as being Who He said He was, doing what He said He did, and going where He said He was going.

What is the Gospel?

Finally, because the gospel has been redefined by heretics who actually deny the gospel taught in the Bible (a la Rob Bell, thosescripture including all miracles and THE HISTORICITY OF ALL EVENTS recorded is basically calling God a liar.” (emphasis mine)

and then

“There is room for someone to be a paedobaptist or a credobaptist, charismatic or cessationist, YOUNG EARTH AND OLD EARTH, Calvinist or non-Calvinist.” (again emphasis mine)

Doesn’t the historicity of all events include Genesis 1 and eliminate old-earthers? Maybe this could have been more carefully worded.

Second, doesn’t the emphasis on “paying the price” for sins necessitate penal substitution as a brick wall doctrine? Admittedly, the article is broken down into three parts, but by my count there are 9 brick wall doctrines here (the Trinity, the special creation of Adam/Eve, attribute of holiness, biblical inerrancy, humanity/deity of Christ, the events of Christ’s life, penal substitution, conscious trust for salvation, and


/// 扩展缓存策略所使用的底层缓存策略（如RedisCacheStrategy）
        /// </summary>
        public Func<IBaseObjectCacheStrategy> BaseObjectCacheStrategy { get { return DomainExtensionCacheStrategy.BaseCacheStrategy; } }

        /// <summary>
        /// 构造函数
        /// </summary>
        /// <param name="domainExtensionCacheStrategy">扩展缓存策略（例如RedisContainerCacheStrategy）</param>
        public CacheStrategyDomainMappingItem(IDomainExtensionCacheStrategy domainExtensionCacheStrategy)
        {
            DomainExtensionCacheStrategy = domainExtensionCacheStrategy;
        }
    }

    /// <summary>
    /// 某一个领域内的缓存策略集合
    /// </summary>
    internalclass CacheStrategyDomainMappingCollection : Dictionary<IBaseObjectCacheStrategy, CacheStrategyDomainMappingItem>
    {
        /// <summary>
        /// 添加或更新缓存策略映射
        /// </summary>
        /// <param name="item"></param>
        public void AddOrUpdate(CacheStrategyDomainMappingItem item)
        {
            var cacheStrategy = item.BaseObjectCacheStrategy();
            base[cacheStrategy] = item;
        }
    }

    /// <summary>
    /// 领域缓存仓库
    /// </summary>
    public class CacheStrategyDomainWarehouse


 /// <param name="cacheStrategyDomain">缓存领域</param>
        /// <returns></returns>
        public static IDomainExtensionCacheStrategy GetDomainExtensionCacheStrategy(IBaseObjectCacheStrategy baseObjectCacheStrategy,
            ICacheStrategyDomain cacheStrategyDomain)
        {
            var identityName = cacheStrategyDomain.IdentityName;
            var mappingCollection = GetMappingCollection(identityName);//当前扩展缓存可能已经注册的所有基础缓存

            if (mappingCollection.ContainsKey(baseObjectCacheStrategy))
            {
                var item = mappingCollection[baseObjectCacheStrategy];
        a cell phone is an “effect” for Fourth Amendment purposes. See United States v
Gardner, 887 F3d 780, 784 (CA 6, 2018) (recognizing a cell phone as an “effect” protected by
the Fourth Amendment); cf. United States v Wurie, 728 F3d 1, 14 (CA 1, 2013), aff’d sub nom
Riley v California, 573 US 373; 134 S Ct 2473; 189 L Ed 2d 430 (2014) (noting that “[t]oday,

1
  The United States Supreme Court in Rakas v Illinois, 439 US 128, 140; 99 S Ct 421; 58 L Ed
2d 387 (1978), “dispens[ed] with the rubric of standing” in the Fourth Amendment context and
stated that “the analysis belongs more properly under the heading of substantive Fourth
Amendment doctrine than under the heading of standing.” However, use of the term “standing”
still persists in search


noted “is qualitatively different from the Fourth Amendment and
provides greater protections.” Id. at 868. By contrast, as already discussed, the Fourth
Amendment and Article 1, § 11 of the 1963 Michigan Constitution are coextensive. Slaughter,
489 Mich at 311.3

3
  Defendant also cites to People v Dziura, unpublished per curiam opinion of the Court of
Appeals, issued December, 15, 2015 (Docket No. 323003), to argue that consent is a prerequisite
to an officer using an individual’s cell phone. Id. at 4. Of course, Dziura, as an unpublished
opinion, is not binding on us. MCR 7.215(C)(1). Moreover, Dziura turned on a consent
analysis, as consent is an exception to the warrant requirement, and there was no search warrant
in that case. Therefore, given the facts, the search in Dziura was valid only if consent was
properly obtained.                                  B. TRESPASS

       Even if we were to find that defendant had standing to challenge the search, we
nevertheless would reject his argument. Defendant argues that Sergeant Buckberry trespassed on
his property by causing a text message to appear on his cell phone.

        Defendant relies on the “trespass test” set out in United States v Jones, 565 US 400; 132
S Ct 945; 181 L Ed 2d 911 (2012), to argue that the text message he received from law
enforcement constituted a “digital trespass,” resulting in


You love Sherlock photo graphics. You love 'What-Would-I-Say?" Now they're together at last in the ultimate exercise in Dadaist whimsy! All graphics are made first, then paired with whatever text the bot generates. The end.Utah Jazz: Dennis Lindsey prepares for first draft in lead seat as Jazz GM

By Bill Oram The Salt Lake Tribune

Published June 26, 2013 8:42 am

NBA • Jazz general manager in position to put his stamp on the team.

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This is an archived article that was published on sltrib.com in 2013, and information in the article may be outdated. It is provided only for personal research purposes and may not be reprinted.

In 10 months on the job, Jazz general manager Dennis Lindsey has proven himself to be a portrait of calm. Always surveying, he never sat in the stands at Jazz games like his fiery predecessor, Kevin O'Connor, preferring instead to stand in the tunnel behind the bench, keeping careful notes.

In that time he was preparing carefully for