applied. Students interested in studying linguistics can pursue the school’s BA in Linguistics.

Careers by Major – Linguistics Each Careers by Major page provides lots of ideas on various career areas, as well as how to gain related skills and experience. Useful resources and job.

Linguistics majors study the similarities and differences between spoken and written languages. While some linguistics majors become linguists, a degree in linguistics can lead to a career in one of several other areas, and the expected pay for linguistics majors really.

note: Major spoilers for Game of Thrones season 8. Strong enough to befriend an enemy, and get murdered for it. Most.

as can that of a fascist regime, so long as you resist them. Your one job is to keep yourself — and the hope containedStart in a runner’s lunge, right leg forward with knee over ankle and left knee on ground with top of your foot flat on the mat. Slowly lift torso and rest hands lightly on right thigh. Lean hips forward slightly, keeping right knee behind toes, and feel the stretch in the left hip flexor. Hold here, or for a deeper stretch, raise arms overhead, biceps by ears. Hold for at least 30 seconds, then repeat on opposite side.

Kneel with a wall or pillar behind you, knees hips-width apart and toes touching the wall. Arch your back to lean back while keeping your hips stacked over your knees. Take your arms overhead and touch your palms into the wall behind you. This bend does not need to be extremely


. .
Since in this case the relation back is not provided for by law, the amendment must fall under Rule 15(c)(2) to be allowed to relate back. Therefore, the cause of action must be found to arise out of the conduct, transaction or occurrence set forth in the original pleading. "The inquiry in a determination of whether a claim should relate back will focus on the notice given by the general fact situation set forth in the original pleading." Rosenberg v. Martin, 478 F.2d 520, 526 (2d Cir.1973), cert. denied, 414 U.S. 872, 94 S.Ct. 102, 38 L.Ed.2d 90 (1973). As the Bankruptcy Appellate Panel for the Ninth Circuit has said in the case of In re Dean,
The basic test is whether the evidence with respect to thesecond set of allegations could have been introduced under the original complaint, liberally construed; or as a corollary, that in terms of notice, one may fairly perceive some identification or relationship between what was pleaded in the original and amended complaints.
11 B.R. 542, 545 (9th Cir. BAP 1981), aff'd, 687 F.2d 307 (9th Cir.1982). While it is still the rule that an amendment which states an entirely new claim for relief based on different facts will not relate back, if a pleading indicates sufficiently the transaction or occurrence on which the claim is based, the amendments which correct the specific factual details will relate back. 3 Moore's Federal Practice ¶ 15.15[3], pp. 15-198 to -208. "The Federal Rules reject the approach that pleading is a game of skill


filing deadline.[3]

*504 CONCLUSION

Because the Section 523(a)(5) Amended Complaint cause of action for determination that the Condo and Enhanced Earnings Awards are nondischargeable cannot relate back to the filing of the Original Complaint, so that it is time barred under Sections 523(a)(15) and 523(c), the Amendment Motion is in all respects denied.
IT IS SO ORDERED.
NOTES
[1]  Section 523 provides, in part, that:

(a) A discharge under section 727, 1141, 1228(a), 1228(b), or 1328(b) of this title does not discharge an individual debtor from any debt
(15) not of the kind described in paragraph (5) that is incurred by the debtor in the course of a divorce or separation or in connection with a separation agreement, divorce decree or other order of a court of record, a determination made in accordanceAmnesty lambastes 'arbitrary dismissals' in Turkey purges

Turkey's President Recep Tayyip Erdogan delivers a statement to reporters alongside US President Donald Trump after their meeting at the White House in Washington, US May 16, 2017. Photograph: (Reuters)

STORY HIGHLIGHTS

Amnesty criticised the dismissals as "carried out arbitrarily on the basis of vague and generalised grounds of ''connection to terrorist organisations"

Emergency rule is due to expire on July 19.

But Erdogan yesterday said it would continue until there was peace, without giving a time limit

Amnesty International today accused Turkey of implementing "arbitrary dismissals" of public sector workers in a series of purges since last year's failed coup.

Over 100,000 people from the public sector including members of the judiciary and armed forces have been dismissed since the attempted overthrow of President Recep Tayyip Erdogan


dismissal was justified," the report said.

According to Amnesty, of those dismissed more than 33,000 are teachers and other employees of the education ministry while over 24,000 are police officers and others from the interior ministry.

Over 8,000 are members of the armed forces, more than 5,000 are academics and include those working in the higher education sector as well as over 4,000 judges, prosecutors and justice ministry officials, it added.

As well as sackings, more than 47,000 have been arrested over alleged links to the movement led by US-based Muslim cleric Fethullah Gulen, accused of ordering the failed coup.

Gulen, who lives in self-imposed exile in Pennsylvania, strongly denies the charges but Turkey alleges his group is a terror group which it dubs the "Fethullah Terror Organisation" (FETO).

Although Western governments anddon’t get many repeat visitors.

At least we USE the bathrooms, however. As I believe I’ve had cause to mention before, kitchen replacement for us would be less than useless, as we never really use them. I haven’t been IN there all year. Nice to have, I suppose, but we won’t need kitchen design any time soon.

It’s a serious problem in both fantasy and sci-fi that the plot ALWAYS has to involve saving the world, or the universe, or all realms. There are almost no exceptions, and you probably don’t know about them because they’re exceptions. It’s like…the scale is bigger, so the stakes have to be bigger and then some. If it’s not a grand battle for the fate of the universe, well…it’s not gonna be printed, or


significantly decreased the expression of the pluripotency marker *SOX2* (Supplementary Fig. [](#supplementary-material-1){ref-type="supplementary-material"}) and increased the expression of the mesoderm transcription factor *MESP1* (Supplementary Fig. [](#supplementary-material-1){ref-type="supplementary-material"}) indicating a departure from pluripotency. Mitochondrial fission genes *DNM1L* and *MFF* and fusion gene *OPA1* were significantly downregulated, while the fission gene *FIS1* was increased (Supplementary Fig. [](#supplementary-material-1){ref-type="supplementary-material"}). The cell proliferation marker *MKI67* and cytokinesis marker *AURKB* were not significantly affected (Supplementary Fig. [](#supplementary-material-1){ref-type="supplementary-material"}). In iPSCs cultured in RPMI+B-27 medium, treatment with M1 did not significantly affect the mRNA levels of the assessed mesodermal or cardiac transcription factors ([Figure 2(a)](#fig2){ref-type="fig"}), nor were pluripotency markers *NANOG* and *SOX2* different from the DMSO control ([Figure 2(b)](#fig2){ref-type="fig"}). Mitochondrial fission and fusion genes were similarly unchanged ([Figure 2(c)](#fig2){ref-type="fig"}). The expression of the cell proliferation marker *AURKB*, but7, and 10 postplating ([Figure 3(b)](#fig3){ref-type="fig"}). Treatment duration slightly impacted the procardiogenic effects of M1 as the treatment during the first 3 days of EB formation, but not during the second 3 days, significantly increased the beating EB rate at 3 days postplating. However, equivalent increases in the percentage of beating EBs were achieved by all M1 treatment groups at 10 days postplating ([Figure 3(b)](#fig3){ref-type="fig"}). Despite the increase in the percentage of beating EBs, the percentage of cardiac troponin T-positive cardiomyocytes within each beating EB at day 10 postplating was similar among all treatment groups ([Figure 3(c)](#fig3){ref-type="fig"}). Directed cardiac differentiation from iPSCs using 5 *μ*M of M1 throughout the 6 days of EB formation was confirmed by quantitative PCR analysis, whereby the cardiac transcription factor *TBX5* ([Figure 3(d)](#fig3){ref-type="fig"})


at all concentrations (data not shown). These findings indicate that while M1 was able to promote EB-based cardiac differentiation, M1 did not influence the electrophysiological properties of cardiomyocytes generated from human iPSCs.

2.3. M1 Does Not Increase ATP Synthase Subunit Expression in Human iPSCs {#sec2.3}
------------------------------------------------------------------------

It has been shown that M1 rescues the expression of Atp5a/b that is lost in Mfn1/2-KO MEFs, suggesting that the pro-fusion effects of M1 may be associated with increased expression of the catalytic ATP synthase subunits *α* and *β* \[[@B20]\]. To evaluate whether M1 might act mechanistically through ATP synthase in iPSCs, we examined the expression of ATP5A and ATP5B mRNA transcripts ([Figure 4(a)](#fig4){ref-type="fig"}) and protein ([Figure 4(b)](#fig4){ref-type="fig"}) in response to 5 and 10 *μ*M of M1 in iPSC-Foreskin-2 iPSCs cultured in pluripotency-maintaining medium forincreased oxidative phosphorylation by these lineages \[[@B8]\].

M1 promoted cardiac differentiation of human iPSCs in 3D but not 2D cultures. While the 2D culture allows for greater control over directed cardiac differentiation, a 3D differentiation method using foetal bovine serum-containing media allows spontaneous cardiac differentiation of pluripotent stem cells by mimicking the physiological embryonic cardiac development processes, including the dynamic cardiomyocyte and noncardiomyocyte interactions \[[@B33], [@B34]\]. Therefore, M1 is unlikely to have the ability to directly activate the cardiac transcriptional programmes needed in the 2D directed cardiac differentiation method, but the pro-mitochondrial fusion effect of M1 might be sufficient to facilitate the spontaneous cardiac differentiation process of iPSCs cultured in 3D embryoid bodies.

In the present study, M1 decreased the mitochondrial fusion protein *OPA1* in the 2D culture of the


on a feeder layer of mitotically inactivated human foreskin fibroblasts (HFF:D551; ATCC, VA, USA) in Dulbecco\'s modified Eagle\'s medium (DMEM)/F-12 GlutaMAX medium supplemented with 20% knockout serum replacement, 0.1 mM 2-mercaptoethanol, 0.1 mM nonessential amino acids, 50 U/mL penicillin/streptomycin (all from Thermo Fisher Scientific, VIC, Australia), and 20 ng/mL recombinant human fibroblast growth factor-2 (Merck Millipore, CA, USA). Spontaneous *in vitro* differentiation of iPSCs was induced through the formation of embryoid bodies (EBs) in suspension as previously described \[[@B44]\]. Briefly, EBs were formed by mechanically dissecting undifferentiated iPSC colonies maintained on a feeder layer into approximately 0.2 mm^2^ pieces using the sharp edge of a flame-pulled capillary. Pieces were transferred onto low attachment plates and cultured in suspension for 6 days in differentiation medium containing DMEM/F-12 GlutaMAX medium supplemented with 20% foetal bovinemeaningful differences were observed in mean changes from baseline in fasting cholesterol (LDL cholesterol and HDL cholesterol) and triglycerides with canagliflozin relative to placebo (Table S1, Supporting Information). Increases in LDL cholesterol (LS mean changes from baseline of 15.0% vs. 7.2%) and HDL cholesterol (5.4% vs. 2.5%) were seen with canagliflozin versus placebo at week 26. Increases from baseline in triglycerides were smaller with canagliflozin (9.8%) than with placebo (14.8%). Changes from baseline in non‐HDL cholesterol were similar with canagliflozin (9.2%) and placebo (8.6%).

Safety and Tolerability {#dom12684-sec-0017}
-----------------------

The overall incidence of AEs at week 26 was 39.8% (n = 43) and 44.4% (n = 48) for the canagliflozin and placebo groups, respectively. The incidence of AEs leading to discontinuation was low for both groups \[0.9% (n = 1) and


New survey shows women will change their lives – and votes – for climate action

A survey of 6500 women, by ACF and 1 Million Women, examines women's attitudes and actions on climate change in the lead-up to this year’s federal election.

A new survey of Australian women’s views on climate change has found nearly nine in ten are ‘extremely concerned’ and in the under-30 bracket one in three are so worried about what global warming is doing to the future that they are reconsidering having children.

One in three (33.4 per cent) of the women surveyed under 30 said they were ‘reconsidering having children or more children because I am increasingly worried that if I have children they will face an unsafe future from climate change’. In the 30–39 agethen your special magick will begin, and your wonders will unfold, and humanity will feel it is waking from the nightmare you are gifting us into a new dawn, the dawn of the time when God will walk amongst us.A God that you will give us, as you have done so many times before.

And your internet stars will have readied us for this deception.And we will believe that the nightmare is over, for a while.

You know, “problem, reaction, solution” again.You even tell us, through your agents, that this is how you control our free will, believing we are so stupid that even in knowledge we are incapable of seeing deception.

But you have erred.

The force which you hope to deceive will prove too strong.The bad dream you are crafting


at the end we will find light.Our light.Whatever the test.

And there are and will be more great tests, tests we all of us sense approaching.

And it already seems overwhelming and irreconcilable in the world, like we are too far gone down this path to stop.And its getting worse.The current flows swifter.And the way ahead has rocks and eddies and currents in the stream laid before us by the owners of this stretch of water we think of as our planet, where they hope we will capsize. .

And can we see them for what they are, our owners?

And can we ever share one dream, and make that dream what we live, and change what is real?Shrug them off?

It's a group thing.We all have to do it.A flash-mob for theborn of the “truth” movements.

Like all revolutions there is and will further be violence.Like all revolutions those involved will believe they do good, only to discover too late that they have been the tool of further, deeper evil.

And the New World Order will be born, with “truth” as its midwife.

And a new “god” and a new “religion” and new “money” and new, “ascended” masters and all manner of weird and wonderful science and gadgets to make people believe they have stepped into a new future when they have in fact been herded into the perfection of a prison that has been two thousand years in the making, designed to milk humanity of its fear and misery for all time.

At least that's the plan.

And the understanding that this plan


exists will be the chief cause of its undoing.And spreading this knowledge becomes crucial.Against the tide of disbelief.

And know: In a world that at some point will lose its connectivity......When our masters see fit to dispossess us of the instruments of communication they have placed in our hands and which they currently use to stoke the fires of this coming revolution they've planned for us the world will be plunged into a darkness, a void, a vacuum.They plan to dispossess us of communication, as any military commander would plan to do, when the time suits them.

So how and why will this knowledge spread?

Deep seated in all of us, even those most afflicted, those most embedded in the false reality there lies the nagging and persistent understanding that thereand the judgements we make and the things that we do from that point onwards are a result of what happens to us.And what happens to us is no accident but a result of the accumulation of learned lessons that dictate other people's behaviour towards us.

And their behaviour is similarly a creation of our actions towards them.

And we assume that all of these things, collectively, represent human nature and the world that we live in.That this is reality.

It's not.It's just a version of reality that has been created by history, by the hands and minds that have shaped the way human beings interact with one another and that have built, layer upon layer, a pyramid of control over the human mind.

And it has been so long in the


false reality.We are coming to understand that how we are is a product of the moulding and shaping of our reality by those who consider themselves our masters.That our masters have their hands on levers of control over our minds that have successfully re-engineered our species into the mess we see before us.And as we come to understand what has been done, so we can conceive of its undoing.

And so this knowledge is key.

And with it, the knowledge that our masters seek to control this emergence of a new, cognisant humanity, or destroy it.

What else do you think all of these faux crises and tribulations are for?

And with that understanding comes the knowledge of the peril we have placed ourselves in, the instruments of destruction we have crafted//
//  BobAxolotlParameters.h
//  AxolotlKit
//
//  Created by Frederic Jacobs on 26/07/14.
//  Copyright (c) 2014 Frederic Jacobs. All rights reserved.
//

#import <Foundation/Foundation.h>
#import "AxolotlParameters.h"

@interface BobAxolotlParameters : NSObject<AxolotlParameters>

@property (nonatomic, readonly)ECKeyPair *ourSignedPrekey;
@property (nonatomic, readonly)ECKeyPair *ourRatchetKey;
@property (nonatomic, readonly)ECKeyPair *ourOneTimePrekey;

@property (nonatomic, readonly)NSData    *theirBaseKey;

- (instancetype)initWithMyIdentityKeyPair:(ECKeyPair*)ourIdentityKeyPair theirIdentityKey:(NSData*)theirIdentityKey ourSignedPrekey:(ECKeyPair*)ourSignedPrekey ourRatchetKey:(ECKeyPair*)ourRatchetKey ourOneTimePrekey:(ECKeyPair*)ourOneTimeKeyPair theirBaseKey:(NSData*)theirBaseKey;

@end


other routes. The length constraints usually limit the maximum number of semi-trucks that can be transported in a piggy back arrangement to three or four, including the mule truck. Transporting semi-trucks in this way can be labor intensive, in that a driver is required for each mule truck.
The maximum allowable height of the mule with piggy back trucks is usually 13.5 feet on designated truck routes. In order to avoid exceeding the maximum allowable clearance height, the piggy back trucks may require partial disassembly for transportation. For example, the exhaust stacks and front wheels are often removed. Drive shafts may also be removed. Axles of piggy back trucks may need to be chained to prevent unwanted rotation during transportation. These steps can be time consuming and costly. Forme but my position was being eliminated, and, effective that same day, I would no longer be employed with the company. Do you know how much that sucks? To hear that you’re a valued member of the team, an asset, and that you did nothing wrong but STILL you can’t work there anymore. I have a whole new level of respect for all of those who worked jobs for years and got laid off because of the recession. To add insult to injury, I had to stay an extra hour to show them how to do all of the reports and spread sheets I work on daily.

It was a Friday. So I decided that that weekend, I was going to get almost blackout drunk then file for unemployment/start


L O W after that. I haven’t stopped buying since.

Next I moved into the world of Colourpop’s highlighters because I didn’t have money for anything else, and at $8 a pop, they were fiscally responsible with a great glow.

Then came Sephora’s Spring VIB sale, and I just had to get the glow kit. I couldn’t decided between That Glow or Gleam but I ended up settling with That Glow. And at 15% off, I was a happy fucking camper.

Then yesterday, on the same day-

I got Jeffree Star’s Skin Frost in Ice Cold and the new TarteXGrav3yard Girl Swamp Queen pallet. I literally bought the pallet for the Gator Wings highlight. The shadows and stuff are nice but DAT GLOW, am I right?

I hope these help you get your public void getFeed() {

        Call<JSONResponse> listCall = mManager.getFlowerService().getAllFlowers();
        listCall.enqueue(new Callback<JSONResponse>() {
            @Override

            public void onResponse(Call<JSONResponse> call, Response<JSONResponse> response) {
                if (response.isSuccess()) {
                    flowerList =  new ArrayList<>(Arrays.asList(response.body().getPosts()));
Toast.makeText(getApplicationContext(),flowerList.get(0).getTitle()+"",Toast.LENGTH_LONG).show();

                    for (int i = 0; i < flowerList.size(); i++) {


determined using flow cytometry and compared among the three age groups. The rate of phagocytosis of serotype K1/K2 isolates was significantly lower in the middle-aged group than that in the younger group (p=0.015) and significantly lower in the older group than those in the middle-aged and younger groups (p=0.025 and p<0.01). In contrast, the rate of phagocytosis of non-K1/K2 isolates was similar in all three age groups at 60 minutes (66.4±1.85%, 65.2±2.0%, and 62.3±1.81%; p=not significant). Thus, as age increases, the ability of neutrophils to phagocytose virulent K1/K2 K pneumoniae decreases. This finding may account for the higher prevalence of K pneumoniae liver abscesses in older patients.if for all $i \not= j$, $C(x_i) - C(x_i \mid x_j) \leq \alpha$.

The tuple of strings $(x_1, \ldots, x_t)$ is mutually $\alpha$-independent (where $\alpha \in {{\mathbb N}}$) if $C(x_{\pi(1)} x_{\pi(2)} \ldots x_{\pi(t)}) \geq C(x_1) + C(x_2) + \ldots + C(x_t) - \alpha$, for every permutation $\pi$ of $[t]$.

Strings dependent with a given string
=====================================

Given a string $x \in \zo^n$, and $\alpha \in {{\mathbb N}}$, how many strings have dependency with $x$ at least $\alpha$? That is we are interested in estimating the size of the set $$A_{x, \alpha} = \{y \in \zo^n \mid C(y) - C(y \mid x) \geq \alpha \}.$$ This is the set of strings about which, roughly speaking, $x$ has at least $\alpha$ bits of information. A related set is $$B_{x, \alpha} = \{y \in \zo^n


\mid C(y \mid n) - C(y \mid x) \geq \alpha \},$$ consisting of the $n$-bit strings about which $x$ provides $\alpha$ bits of information besides the length $n$. Clearly, $B_{x,\alpha} \subseteq A_{x, \alpha}$, and thus an upper bound for $|A_{x,\alpha}|$ also holds for $|B_{x,\alpha}|$, and a lower bound for $|B_{x,\alpha}|$ also holds for $|A_{x,\alpha}|$.

We show that for some polynomial $p$ and for some constant $C$, for all $x$ and $\alpha$ except some special values, $$(1/p(n)) \cdot 2^{n-\alpha} \leq |A_{x, \alpha}| \leq C 2^{n-\alpha},$$ and, in case $\alpha(n)$ is computable from $n$, $$(1/C) \cdot 2^{n-\alpha} - p(n)2^{\alpha} \leq |B_{x, \alpha}| \leq C 2^{n-\alpha},$$ The upper bounds for the sizes of $A_{x, \alpha}$ and $B_{x, \alpha}$ can be readily derived. Observe that the set $A_{x, \alpha}$ is included in $\{technique based on Kolmogorov complexity extractors, as explained in the Introduction. We use the following theorem which can be obtained by a simple modification of a result from [@zim:c:impossibamplific].

\[t:kolmextractor\] For any computable functions $s(n), m(n)$ and $\alpha(n)$ with $n \geq s(n) \geq \alpha(n) + 7 \log n $ and $m(n) \leq s(n) - 7 \log n$, there exists a computable ensemble of functions $E: \zo^n \times \zo^n \mapping \zo^{m(n)}$ such that for all $x$ and $y$ in $\zo^n$

-   if $C(x) \geq s(n), C(y \mid n) \geq s(n)$ and $C(y \mid n) - C(y \mid x) \leq \alpha(n)$

-   then $C(E(x,y) \mid x ) \geq m(n) - \alpha(n) - O(1)$.

\[t:conditionalestimate\] Let $\alpha(n)$ be a computable function. For every sufficiently large natural number $n$, for every $x \in


3 \log n}$ strings with Kolmogorov complexity less than $\alpha + 3 \log n$. We discard such strings from $x_1, \ldots, x_t$ and assume that $x_1, \ldots, x_{t'}$ are the strings that are left. Since $t < 2^{\alpha + 3 \log n} + t'$, we need to show that $t' \leq n^3 2^\alpha$.

For $1 \leq i \leq t'$, let $k_i = C(x_i)$ and let $x^*_i$ be the shortest description of $x_i$ as described in the Preliminaries. Let $\beta = \alpha + 3 \log n$ (we assume that $\alpha \leq n - 3 \log n$, as otherwise the statement is trivial). We show that the prefixes of length $\beta$ of the strings $x_1, \ldots, x_{t'}$ are all distinct, from which we conclude that $t' \leq 2^\beta = n^3 \cdotHavana, Sep 17 (Prensa Latina) Emotion, stress, but above all discipline and training are some of the experiences of Brigadier General Arnaldo Tamayo, the first Cuban cosmonaut who remembers these experiences on the occasion of the 40th anniversary of his trip to space.


are correct that since the values are in $\Bbb N$ that means $a_n$ must be unbounded, but if the values were in $\Bbb R$ it would not.  For this problem it is not important.
You can get halfway there by making $b_{n+1}=a_n$ and choosing $b_1$ to be whatever you want.  Clearly $a_n$ is a subsequence of $b_n$.  Now if $a_n$ consists of a series of ramps, each higher than the last, then returns to $1$, so $1,2,1,2,3,4,5,1,2,3,4,5,6,\dots$ you are home.

60(b)(i), claiming it was not granted an opportunity to prepare a rebuttal. On the basis of the Human Service Center's motion contending it was not given an opportunity to prepare a rebuttal to I.K.'s argument under N.D.C.C. § 25-03.1-22, the trial court rendered its May 8, 2003, order. The record supports the claim of surprise. The district court did not abuse its discretion by vacating the April 28, 2003, order.

III
[¶ 12] I.K. contends the district court erred in ordering her to "continue to take Seroquel until May 12, 2004[,] a period of one year, or until further order of the Court." I.K. argues this provision was included in the order even though none of the requirements of N.D.C.C. § 25-03.1-18.1 were followed, and the permissible duration of such


revealed that she is largely self-sufficient, cooperates in her treatment, and is of no harm to herself or to others.
[¶ 19] Two witnesses other than I.K. testified at the May 12, 2003, continuing treatment hearing: I.K.'s primary doctor, Ed Yabut, and her case manager from the South Central Human Service Center, Kimberly Weyer. Dr. Yabut testified I.K. has an exaggerated belief that she has a urinary tract infection and she does not believe that she has responded to the treatment and fails to acknowledge there may be nothing wrong with her. Dr. Yabut also testified that after he examined I.K. because she complained of swelling in her hands, which would be a side effect of Seroquel, he found no objective evidence of any inflammation.
[¶ 20] Dr. Yabut testified                  0.365

p-values \<0.05 indicate a non-normal distribution.

Wilcoxon signed-rank tests [@pone.0087065-Siegel1] were used for assessing whether the d' scores were significantly different from zero in all combinations of timbre and pitch distances.

The interaction between pitch and timbre was assessed separately in the attend-timbre and attend-pitch conditions by the Scheirer-Ray-Hare extension of the Kruskal-Wallis test ([@pone.0087065-Sokal1], a non-parametric two-way ANOVA, factors: distance along the attended and un-attended dimension).

Nonparametric Spearman rank correlations [@pone.0087065-Siegel1] were used for calculating correlation coefficients between the d' scores and the variations along the un-attended dimension ([Figure 2](#pone-0087065-g002){ref-type="fig"}) and a non-parametric ANCOVA based on ranks [@pone.0087065-Conover1] was used for testing the hypotheses of equal slopes and intercepts.

Results {#s3}
=======

[Figure 2](#pone-0087065-g002){ref-type="fig"} shows


the average d' (mean±SE) across subjects (57 subjects in the attend-timbre condition and 21 subjects in the attend-pitch conditions), obtained from the answers given to identical and different stimulus pairs along the attended dimension. In all conditions, the discriminability significantly decreased as the variation in the un-attended dimension grew larger, indicating interference between pitch and timbre (Spearman rank correlations were all negative and significantly different from zero, indicated in [Figure 2](#pone-0087065-g002){ref-type="fig"}). Nevertheless, a degree of distinction between timbre and pitch was retained under all interference conditions: the ability of subjects to detect change at significantly-greater-than chance levels was never abolished by variations along the irrelevant dimension (the d' scores in all conditions remained significantly different from zero - Wilcoxon signed-rank tests, all p\<0.001). In other words, the variationsall 3 pitch distances (a "ceiling" effect due to the fact that a semitone is already an easily discriminable pitch interval). The main effect of the un-attended dimension was significant in both conditions (attend-timbre: H(3) = 82.89, p\<0.001; attend-pitch: H(3) = 33.11, p\<0.001), indicating a clear interference between pitch and timbre both when subjects judged timbre and when they judged pitch. The interaction term was not significant (attend-timbre: H(6) = 3.31, p = 0.77; attend-pitch: H(6) = 0.14, p = 0.99), indicating that the effect of variations along the un-attended dimension were consistent across variations along the attended dimension.

The rank analysis of covariance [@pone.0087065-Conover1] confirmed these results in both attend-timbre and attend-pitch conditions. We considered the ranked d' values, and tested the linear regression model of 3 lines with equal slopes and different intercepts against the model with different slopes


    0.41
  S10            0.47            0.88                        0.75                                    0.53

**Note:** The table shows uncorrected p-values for the slopes of the individual regressions of the standard deviation of the matched tones on timbre levels for each fundamental frequency f~0~. Uncorrected p-values are shown in this instance because thesecontaminants, fatty acids, disease).[31](#rcm8272-bib-0031){ref-type="ref"}, [32](#rcm8272-bib-0032){ref-type="ref"} Thus, researchers need to efficiently analyze tissue samples and have been transitioning from using immunoassays to more sophisticated analyses, like liquid chromatography/tandem mass spectrometry (LC/MS/MS).[28](#rcm8272-bib-0028){ref-type="ref"}, [30](#rcm8272-bib-0030){ref-type="ref"}

LC/MS/MS analysis allows for greater utility of samples collected from rarely encountered species, such as marine mammals. For example, eight different hormones have been analyzed in a single 0.40 g blubber sample using LC/MS/MS[28](#rcm8272-bib-0028){ref-type="ref"} compared with a single hormone being measured in 0.15 g using ELISAs.[33](#rcm8272-bib-0033){ref-type="ref"} LC/MS/MS measures the amount of the actual target analyte, resulting in low cross‐reactivity of metabolites and greater accuracy of actual steroid hormone concentrations in samples.[34](#rcm8272-bib-0034){ref-type="ref"} Recently, a variety of LC/MS/MS methods have been developed to measure multiple hormones in a single sample of marine mammal blubber,[28](#rcm8272-bib-0028){ref-type="ref"}, [30](#rcm8272-bib-0030){ref-type="ref"}, [34](#rcm8272-bib-0034){ref-type="ref"} whale blow,[35](#rcm8272-bib-0035){ref-type="ref"} and serum.[34](#rcm8272-bib-0034){ref-type="ref"}, [36](#rcm8272-bib-0036){ref-type="ref"} Serum


for thousands of years.[15](#rcm8272-bib-0015){ref-type="ref"}, [43](#rcm8272-bib-0043){ref-type="ref"} In addition, there has been evidence of degradation of progesterone in cetacean blubber,[3](#rcm8272-bib-0003){ref-type="ref"} which contains lipid‐associated hormones similar to bone. Therefore, steroid hormones most likely degrade over millennia in bone and need to be corrected for lipid degradation and leeching to compare steroid hormone concentrations across thousands of years. A mean percent lipid correction factor was used to correct potential lipid composition differences among time periods. Bones (*n* = 12, 10, and 12, for archaeological, historical, and modern bone, respectively) from each sample time period were lipid extracted using a modified (2:1 chloroform/methanol) Soxhlet procedure after Schlechtriem et al.[44](#rcm8272-bib-0044){ref-type="ref"} A one‐way analysis of variance (ANOVA) followed by Tukey\'s pairwise comparison determined that mean percent lipid of modern bone (4.83 ± 1.78%) was significantly higher than archaeological (2.71 ± 1.96%)60°C for 10 min, transferred to autosampler vials, and immediately analyzed. The second aliquot of each extract was derivatized with the AB Sciex keto derivatization kit (AB Sciex) just prior to LC/MS/MS analysis, and 50 μL of reagent was added. The reaction time was 60 min at room temperature. Finally, the samples were transferred to autosampler vials and immediately analyzed.

An Agilent 1200 rapid resolution liquid chromatography (LC) system coupled to an Agilent 6460 series QqQ mass spectrometer (MS) was used to analyze all samples after derivatization at the Bindeley Bioscience Center at Purdue University, IN, USA. For the dansyl chloride derivatives, the following conditions were used. A Waters Xbridge C18 column (2.1 mm × 100 mm, 3 μm) was used for LC separation. The buffers were (A) water +0.1% formic acid and (B) acetonitrile


for reference in ng/g lipid (Tables [3](#rcm8272-tbl-0003){ref-type="table"}A and [3](#rcm8272-tbl-0003){ref-type="table"}B). The samples used for the physiological validations are listed in Appendix [2](#rcm8272-app-0002){ref-type="app"}.

The data used for tissue comparison analysis were log transformed to normalize distribution of steroid hormone concentrations in bone, blubber, and serum. The samples used for the tissue comparison are listed in Appendix [3](#rcm8272-app-0003){ref-type="app"}. Three factorial ANOVA tests were used to test for differences in mean concentrations of steroid hormones among all tissues, between sexes, and the interaction of sex and tissue. If the differences among hormone concentrations were statistically significant among tissues, between sexes, and/or had a significant interaction of tissue and sex, a Tukey post hoc test was used to elucidate specific differences among the factors ("tissue", "sex", "sex\*tissue") for each hormone. The majority of animals were[58](#rcm8272-bib-0058){ref-type="ref"}, [59](#rcm8272-bib-0059){ref-type="ref"} Thus, surges of estradiol are more difficult to capture in a long‐term reservoir tissue, such as bone, compared with progesterone and could result in ND samples for modern female walrus bone samples (*n* = 8 of 10). While estradiol concentrations are discussed in more detail below, estradiol can be locally synthesized in bone,[18](#rcm8272-bib-0018){ref-type="ref"}, [60](#rcm8272-bib-0060){ref-type="ref"} and most likely has a different reservoir time in bone compared to the other steroid hormones in this study, which could contribute to the relatively high number of ND samples. The modern female samples with below detectable concentrations of estradiol were all collected between the months of April to May, which is outside the timeframe when female walruses would go into estrus and have high estradiol concentrations.[51](#rcm8272-bib-0051){ref-type="ref"}, [58](#rcm8272-bib-0058){ref-type="ref"} Additionally, one of the animals was


in female pinnipeds before entering estrus,[62](#rcm8272-bib-0062){ref-type="ref"} but all modern females used for the tissue comparison were collected in May, a time of low circulating estradiol concentrations (Appendix [3](#rcm8272-app-0003){ref-type="app"}). Additionally, surges in estradiol have not always been documented in walruses before estrus, but instead may be more sporadic.[58](#rcm8272-bib-0058){ref-type="ref"} Hence, in 2015 there were most likely no surges in estradiol to detect in blubber or serum (Table [7](#rcm8272-tbl-0007){ref-type="table"}). Estradiol has been measured in the blubber of gray whales (Eschrichtius robustus) by the use of EIAs with detectable concentrations in male calves, juveniles, adults, and adult females.[63](#rcm8272-bib-0063){ref-type="ref"} However, there were lower concentrations (max \~0.5 ng/g of blubber) detected in samples with greater mass (100--200 mg).[63](#rcm8272-bib-0063){ref-type="ref"} Our sample masses were higher, 200--300 mg of blubber, and we used LC/MS/MS for detecting hormone concentrations which would mostaverage of blubber.[10](#rcm8272-bib-0010){ref-type="ref"}

### 3.4.2. Estradiol {#rcm8272-sec-0029}

Estradiol concentrations were significantly different between years (ANOVA, *P* \< 0.001, Table [7](#rcm8272-tbl-0007){ref-type="table"}). Thus, 2014 samples were tested for estradiol concentration differences among tissues, between sexes, and the interaction of sex and tissue sampled (Table [7](#rcm8272-tbl-0007){ref-type="table"}). Samples from 2014 had similar mean estradiol concentrations between sexes with no effect of the interaction of sex and tissue (*P* = 0.06, 0.96, respectively), but concentrations were significantly different among tissues (*P* \< 0.001). Bone and blubber estradiol concentrations were similar (Tukey\'s post hoc test, *P* = 0.51), but both were significantly higher than serum for 2014 samples (*P* \< 0.001, \< 0.001, respectively). Samples from 2015 only contained one female, thus only differences among tissues were tested (Table [7](#rcm8272-tbl-0007){ref-type="table"}). In contrast to the 2014 samples, the samples from 2015 had similar concentrations among tissues (*P* = 0.38). Bone turnover rate


and sex determined from hunter observations. Estimated ages were based on counting cementum growth layers in the walrus teeth. Tissue labels for hormone concentrations (i.e., last four columns) are abbreviated as follows: bone (B), blubber (Bl), and serum (S). Hormones are abbreviated as follows: cortisol (C), estradiol (E), progesterone (P), and testosterone (T). All units are in ng/g of tissue or ng/mL for serum Catalog nameProject numberTissues analyzedSexReproductive infoDate collected \[D‐M‐Y\]LocationAge classEstimated age \[years\]SP \[ng/mL\]ST \[ng/mL\]SC \[ng/mL\]SE \[ng/mL\]BlP \[ng/g\]BlT \[ng/g\]BlC \[ng/g\]BlE \[ng/g\]BP \[ng/g\]BT \[ng/g\]BC \[ng/g\]BE \[ng/g\]S14--0002AWAL126Bone, serumMale16‐May‐14SavoongaAdult181.5910.6810.6885.25‐‐‐‐8.595.661.38106.58S14--0005WAL128.1Bone, blubberMale‐22‐May‐14SavoongaSubadult24‐‐‐‐6.443.8210.74137.9865.3123.143.34121.22S14--0007WAL129.1Bone, blubber, serumMale‐2014SavoongaUnknown189.215.2023.8094.336.871.815.09151.6925.7517.183.61117.06S14--0011WAL132.1Bone, blubber, serumFemaleNone22‐May‐14SavoongaUnknown‐5.2410.6123.3589.5321.239.687.97112.9621.3156.212.85100.57S14--0014WAL133.1Bone, blubberMale‐5‐May‐14SavoongaUnknown‐‐‐‐‐9.8920.958.39171.8810.8912.378.20107.96S14--0018WAL135.1Bone, blubberMale‐22‐May‐14SavoongaAdult9‐‐‐‐4.0412.5213.17126.2828.2015.2432.37112.48S14--0021WAL137.1Bone, blubberMale‐22‐May‐14SavoongaUnknown26‐‐‐‐3.9211.183.69129.482.682.180.22116.05S14--0022WAL138.1Bone, blubber, serumMale‐2014SavoongaSubadult152.3214.7916.89160.445.5714.205.74116.331.877.090.24121.12S14--0024WAL139.1Bone, blubberMale‐4‐May‐14SavoongaSubadult28‐‐‐‐3.2724.624.47109.51264.2064.480.36194.85S14--0029WAL141.1Bone, blubber, serumMale‐24‐May‐14SavoongaAdult193.8014.0319.6989.645.0621.595.98106.9319.1214.618.00103.32S14--0034WAL142.1Bone, blubber, serumMale‐22‐May‐14SavoongaAdult154.809.1514.8494.052.9512.602.34111.3524.7216.196.54113.30S14--0035WAL143.1Bone, blubberMale‐11‐May‐14SavoongaAdult14‐‐‐‐5.3912.034.29110.9830.2618.2522.14116.85S14--0036WAL144.1Bone, blubber, serumMale‐22‐May‐14SavoongaAdult123.437.0123.9186.535.488.125.30125.22133.1015.902.91127.36S14--0038WAL145Bone, blubberMale‐4‐May‐14SavoongaAdult18‐‐‐‐3.515.274.00112.36124.3713.521.88100.31S14--0039WAL146Bone, blubberMale‐4‐May‐14SavoongaAdult17‐‐‐‐15.717.665.96132.7661.2512.313.15127.49S14--0040WAL147.1Bone, blubber, serumMale‐4‐May‐14SavoongaAdult200.937.0927.8096.817.438.805.29118.631.773.992.61114.77S14--0044WAL148Bone, blubberMale‐4‐May‐14SavoongaAdult23‐‐‐‐9.146.5010.12120.3438.9315.0511.12113.32S14--0045WAL149.1Bone, blubber, serumFemaleCalf, Yearling, and Lactating4‐May‐14SavoongaAdult163.245.9666.3995.7568.356.248.55118.7517.026.890.76114.61G14--0002WAL151.1Bone, serumFemaleCalf and Lactating25‐May‐14GambellAdult148.009.5225.5399.75‐‐‐‐13.7211.3616.91119.38G14--0005WAL152.1Bone, blubber, serumMale‐4‐May‐14GambellAdult‐5.009.0912.7583.578.415.333.59116.7726.0119.16118.84100.84G14--0011WAL153.1Bone, blubber, serumFemalePregnant17‐May‐14GambellAdult154.404.6433.0882.91141.9816.797.48127.607.6913.851.63124.14G14--0036WAL154.1Bone, blubberMale‐4‐May‐14GambellAdult14‐‐‐‐3.0119.846.35121.9611.144.840.77124.46G14--0046WAL156.1Bone, blubber, serumFemaleCalf and Lactating4‐May‐14GambellAdult‐4.407.6880.3791.4985.077.574.35113.8410.136.720.73115.22S15--027WAL233Bone, blubberMale‐2015SavoongaUnknown‐‐‐‐‐1.071.771.131.971.1919.0013.601.44S15--039WAL234Bone, <country>TestCountry</country>
                    </address>
                </addressList>
            </sdnEntry>
        </sdnList>";

var xml = XElement.Parse(text);
var dates = xml.Elements("publshInformation").Select(pi => pi.Element("Publish_Date").Value);
dates.ToList().ForEach(WriteLine);

If you'd like to use XDocument instead of XElement:
var xml = XDocument.Parse(text);
var dates = xml.Element("sdnList")
               .Elements("publshInformation")
               .Select(pi => pi.Element("Publish_Date").Value);


have lost the sensation in their nipples.

While I still enjoyed touching and fondling them, I found out over time there was little to gain from undue sucking.

Also guys, encourage you lady to play with yours. To me it feels wonderful and almost every woman I have ever been with really enjoyed playing with them once they found out how much I liked it.

You cannot post new topics in this forum.
You cannot reply to topics in this forum.
You cannot delete your posts in this forum.
You cannot edit your posts in this forum.
You cannot create polls in this forum.
You cannot vote in polls in this forum.node involvement. Subsequent analysis of certain genes identified in the microarray analysis were confirmed by quantitative real-time PCR. Our data suggest that microarray technology could discriminate between the involvement of regional lymph node in colon cancer where apoptosis-related genes would be implied. This preliminary analysis also suggests that the gene expression profile may be useful in improving risk-group stratification.


Q:

jquery - undesired jump effect (it occurs often and I don't understand why)

On the code above, we:
1) Click on Categoria A and then,
2) click on one of the bold titles that appear.
You will notice that, while expanding instead of the movement to be smooth, it jumps near the end of the show process. (It seems that when it finds a
 he jumps);
What could be the cause of such a behavior?
Here his the related code: code:
$('#btCategoriaA').click(function() {
            $('#btCategoriaA').toggleClass('selecionado');
            $('#listaCategoriaA').slideToggle('slow', function() {
           });
        });

Информация о доставке

И в файле стилей:
.head_cont {
font-family: 'PT Sans', sans-serif;
font-size: 12px;
font-weight: bold;
font-style: normal;
text-transform: none;
display: inline;
}

.head_cont_delivery {
font-family: 'PT Sans', sans-serif;
font-size: 12px;
font-weight: bold;
font-style: normal;
text-transform: none;
display: inline;
width: 100px;
height: 40px;
overflow: hidden;
}

A:

Это нормальное поведение zoom'a, он немного для другого был придуман. Я бы вам посоветовал использовать media queries, дабы адаптировать сайт под разные разрешения.


tell you that I am one of the worst offenders. I respond to emails quickly and late at night because I check my email every 10 minutes. Earlier this year, I offered a live stream homework help after dinner on some nights. I use Remind , which allows me to quickly send out announcements to all of my students but also gives them further access to my help outside of school hours. I have recognized that some of these practices are unhealthy and unsustainable. What may be a bigger issue, though, is the message that my actions send and the expectations that they set. If I respond to a parent quickly at 7 pm, that now becomes an expectation. It also says that my time at home isstudents find that balance.3. Consider ways to teach work habits as part of your curriculum. Have students intentionally reflect on how they are using their work time. They may be legitimately strapped for time or they may be wasting more time than they realize.4. Do your best to model healthy work habits.5. We want students who are willing to work hard who also can develop a healthy work-life balance. Reconsider the culture you are building in your class and really examine whether or not it is helping students develop those traits.6. Talk to professionals in other fields and see what work-life balance looks like for them. If we are preparing students for the professional world, we need to know what companies are doing right now and what direction


powerpoint-electrical-sales

Contributor: Theodore Gray

Acquired: 20 January, 2007

Text Updated: 11 February, 2007

Price: $2

Size: 4"

Purity: 99%

Dental mercury.

Mercury is used to this very day to make dental amalgams, tooth fillings made with a mixture of mercury and zinc. It's claimed that the mercury stays permanently locked in the filling and poses no risk, but do you really believe that? Last time I had fillings I asked them to use the alternative polymer-ceramic material. I have another sample of dental mercury which came with the necessary zinc pellets and mixing apparatus, but this bottle is much more attractive than the plastic eye dropper that came with that other one.

Reader Andrzej Kasperowicz pointed out the following fascinating videos, which show mercury vapor wafting up from a disturbed amalgam filling: http://youtube.com/watch?v=9ylnQ-T7oiA

http://iaomt.org/videos

http://youtube.com/watch?v=MfVsUuhoFWY Kind of scary tothere is one small, bare cell along with the three batteries, each of which contains three of those cells. Technically "battery" means multiple cells put together. A typical AA, C, or D battery is not really a battery at all but rather a single cell. 9V batteries, on the other hand, are genuine batteries because they contain 6 individual cells inside.

Source: Alec Wright

Contributor: Theodore Gray

Acquired: 1 December, 2008

Text Updated: 2 December, 2008

Price: $3

Size: 2"

Purity: <20%

Tuna fish.

All fish contains mercury, and the larger, older, and fattier the fish is, the more mercury it's likely to have. Canned albacore tuna is big and old, though not terribly fatty, so it likely has an intermediate amount of mercury. Whether you think this is a problem depends on whether you trust the


University of Utah got patents on the BRCA genes and then licensed them exclusively to Myriad Genetics.

CHEO tests kids for Long QT along with more than 20 other genetic disorders. But it can't get certified by the Ontario government to do the test itself because of patents owned by the University of Utah, according to the lawsuit.

"Genes are not inventions," said Dr. Gail Graham of the hospital's genetics department during a press conference on Monday. "They belong to all of us."

Right now, CHEO pays about $4,500 (US) to do the tests for Long QT syndrome by sending the samples off to a lab in the United States. The hospital says it could do the tests itself for about half the cost, if it were free of the patents.

Thewas, and is, simply emblematic of the ease and speed that can come as part of the trade when going from straightening your hair to letting it do its what it does, naturally. The problem is, the wash n' go hasn't been working for everybody. From the beginning, many early adopters were less than pleased with the results of styling their hair this way and expressed their concerns on the various hair-centric forums. However, in the excitement over this trend – which was not only a timesaver, but also a paradigm-shifting experience for many of those who tried it – these voices were usually shushed. Naysayers were met with replies hinting that they had a problem with their texture and its natural appearance, rather than with this much-cherished


Court’s order granting summary disposition to defendants
pursuant to MCR 2.116(C)(7). The court applied the two-year
statute of limitations set forth in MCL 500.8124(2); MSA
24.18124(2) and found that plaintiffs’ claims were time-barred.
We affirm.

Pursuant to his authority under chapter 81 of the insurance
code governing the supervision, rehabilitation, and liquidation
of insolvent insurance companies, MCL 500.8101 et seq.;
MSA 24.18101 et seq., the insurance commissioner commenced
liquidation proceedings against ACLIC in Ingham Circuit Court.[1] The
court ordered ACLIC into liquidation on March 2, 1992. In
February and March of 1994, plaintiffs filed complaints against
defendants, the former agents of ACLIC, claiming that the
commission payments made to defendants during the year preceding
the order of liquidation constituted preferential transfers
recoverable under MCL 500.8128; MSA 24.18128. In June 1994, the
Legislature amended the preference provisions of the insurance
code to expressly exempt agents’ commissionsbrought pursuant to MCL 500.8121(1); MSA 1812(1) and
MCL 500.8133; MSA 24.8133, fall clearly within the ambit of the
two-year limitations period. We are not persuaded by plaintiffs’
attempts to characterize the claims as actions on a contract,
personal actions, or claims to enforce noncontractual money
obligations founded upon a judgment. The Ingham Circuit Court did
not err in granting summary disposition to defendants.

For delinquency proceedings commenced after January 1,
1990, and notwithstanding any other provision of law,
commissions paid to insurance agents or agencies by an
insurer in the ordinary course of business at a time when the
insurer was authorized to transact such business are not
recoverable unless the agent or agency is affiliated with the
insurer or produces more than 10% of the insurer’s premium.


what she said.
I'm just going to mention
it because I like it.
Emily Thornberry started
to talk about herself
as a tough old bird,
because apparently that's
what Len McCluskey called her.
And she's taken
that as a excellent,
useful piece of
personal branding,
a bit like Theresa May adopted
'bloody difficult woman'.
Because she's going
to need something
to break through against
these two, who are quite
ideasy and very outspoken.
There is an interesting
question here, which is that,
right up to this
leadership contest,
almost everybody in the
Labour party was saying,
we really need a woman leader.
We're the only major
political party that's
ever been led by a woman.
It is notable.
Let's face it.
Yeah.
And so that is an
issue for Keir Starmer.
There are plenty of people in
the Labour party who will agree
with that.
So I think, in a way, what
Emily Thornberry was reminding
people is, actually,
if it's him or me,
and you want a woman
leader,
China is laying the groundwork for a post-American world order - tosh
https://www.washingtonpost.com/news/theworldpost/wp/2018/07/27/america-china/
======
zapita
I would argue that, more than anyone else, the US is laying the groundwork for
a post-American world order. It has been on that course since the post-9/11
insanity, and the trend has only accelerated since.

~~~
frockington
As an American I would be happy to see someone else take responsibility. If
China thinks they can somehow bring stability to the Middle East then give
them a shot. At least when they inevitably descend into chaos again it wont be
us having to babysit. I think many Americans are hoping China tries to take a
leadership role in Asia and near neighbors

~~~
astebbin
>I think many Americans are hoping China tries to take a leadership role in
Asia and near neighbors

Could you elaborate on this? My impression was that


insane to invade China, though. "Never get involved in a land
war in Asia". Especially never get involved in a land war in Asia against
someone with an army the size of China's.

> 2\. Its embracing culture will attract more immigrants.

This advantage the current administration seems to be working as hard as
possible to destroy. As far as I know, though, this is still an advantage for
the US compared to China.

> 2\. Its [China's] economy is still underdeveloped, therefore economic growth
> is a lot easier.

It's not nearly as underdeveloped as it used to be. Further growth will be
significantly harder than past growth was. Can China keep it going? I don't
know.

~~~
Leary
Nobody is capable of invading China, that is true. But American mainland is a
lot more secure than China's. Any military conflict willused to reverse this in special situations

    WARNING: Assembler code versions rely on PLATFORM_BYTE_ORDER being set.
    This define will hence be redefined later (in section 4) if necessary
*/

#if 1
#  define ALGORITHM_BYTE_ORDER PLATFORM_BYTE_ORDER
#elif 0
#  define ALGORITHM_BYTE_ORDER IS_LITTLE_ENDIAN
#elif 0
#  define ALGORITHM_BYTE_ORDER IS_BIG_ENDIAN
#else
#  error The algorithm byte order is not defined
#endif

/*  2. VIA ACE SUPPORT */

#if !defined(__APPLE__) && defined( __GNUC__ ) && defined( __i386__ ) \
 || defined( _WIN32   ) && defined( _M_IX86  ) \
 && !(defined( _WIN64 ) || defined( _WIN32_WCE ) || defined( _MSC_VER ) && ( _MSC_VER <= 800 ))
#  define VIA_ACE_POSSIBLE
#endif

/*  Define this option if support for the VIA ACE is required. This uses
    inline assembler instructions and


is only implemented for the Microsoft,
    Intel and GCC compilers.  If VIA ACE is known to be present, then defining
    ASSUME_VIA_ACE_PRESENT will remove the ordinary encryption/decryption
    code.  If USE_VIA_ACE_IF_PRESENT is defined then VIA ACE will be used if
    it is detected (both present and enabled) but the normal AES code will
    also be present.

    When VIA ACE is to be used, all AES encryption contexts MUST be 16 byte
    aligned; other input/output buffers do not need to be 16 byte aligned
    but there are very large performance gains if this can be arranged.
    VIA ACE also requires the decryptiongf_c2) << 1) ^ ((u - (u >> 7)) & gf_c4)
*/

/* Work out which tables are needed for the different options   */

#if defined( ASM_X86_V1C )
#  if defined( ENC_ROUND )
#    undef  ENC_ROUND
#  endif
#  define ENC_ROUND   FOUR_TABLES
#  if defined( LAST_ENC_ROUND )
#    undef  LAST_ENC_ROUND
#  endif
#  define LAST_ENC_ROUND  FOUR_TABLES
#  if defined( DEC_ROUND )
#    undef  DEC_ROUND
#  endif
#  define DEC_ROUND   FOUR_TABLES
#  if defined( LAST_DEC_ROUND )
#    undef  LAST_DEC_ROUND
#  endif
#  define LAST_DEC_ROUND  FOUR_TABLES
#  if defined( KEY_SCHED )
#    undef  KEY_SCHED
#    define KEY_SCHED   FOUR_TABLES
#  endif
#endif

#if ( FUNCS_IN_C & ENCRYPTION_IN_C ) ||


define ISB_SET
#  endif
#endif

#if !(defined( REDUCE_CODE_SIZE ) && (defined( ASM_X86_V2 ) || defined( ASM_X86_V2C )))
#  if ((FUNCS_IN_C & ENC_KEYING_IN_C) || (FUNCS_IN_C & DEC_KEYING_IN_C))
#    if KEY_SCHED == ONE_TABLE
#      if !defined( FL1_SET )  && !defined( FL4_SET )
#        define LS1_SET
#      endif
#    elif KEY_SCHED == FOUR_TABLES
#      if !defined( FL4_SET )
#        define LS4_SET
#      endif
#    elif !defined( SBX_SET )
#      define SBX_SET
#    endif
#  endif
#  if (FUNCS_IN_C & DEC_KEYING_IN_C)
#    if KEY_SCHED == ONE_TABLE
#    The 5-Second Trick For online coursework help

The 5-Second Trick For online coursework help

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All members of the cohort take pleasure in the shared experiences and varied perspectives of people in the team. Undergraduate Cohort

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The amount of IGCSE subjects should really I choose? It genuinely will depend on the intent for which you are taking them. The Conference


"inválido"    // $valor = -0.0
string(9) "inválido"    // $valor = 1.0

Veja funcionando no Ideone | Repl.it
Solução 2
Outra forma de implementar a função seria explicitar o tipo definindo-o na lista de argumentos da função:
function valida_variavel_zero_um(int $valor)
{
    if ($valor != 0 && $valor != 1)
    {
        return "inválido";
    }

    return $valor;
}

Veja funcionando no Ideone | Repl.it
Porém, ao chamar a função com valores não inteiros, o PHP tentará convertê-los para o tipo int antes de passá-los como parâmetro. Isto é, chamar a função valida_variavel_zero_um(false) retornaria 0 e valida_variavel_zero_um(true) retornaria 1, pois false e true, quando analisados como inteiros, são 0 e 1 respectivamente. Isso pode gerar problemasR) with an FDR for *p*-values adjustment. Differentially expressed genes (DEGs) (upregulated or downregulated) had an FDR (adjusted *p*-value) \< 0.05 and an absolute FC (fold change) ≥ 1.5. By comparing DEGs with PIGs in every cancer type, the differentially expressed PIGs were obtained, as shown in Additional file [4](#MOESM4){ref-type="media"}: Table S3.

Gene set enrichment analysis {#Sec6}
----------------------------

The "phyper" function (R, 2013) based on hypergeometric distribution method was used to conduct the enrichment analysis of prognostic genes among 22 cancer types. R code was as flowing: $$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}


LUAD, SARC, and LGG) involved in the TCR signaling pathway. Six genes (ZAP70, LCK, CD3E, CD3G, CD3D, and CD247) played a key role in triggering the TCR signaling pathway \[[@CR34]\]. The results of this study indicated that high expression levels of the PIGs related to the TCR signaling pathway were associated with poor OS in LGG but long-term OS in 5 cancer types (BRCA, CESC, HNSC, LUAD, and SARC). Our findings are consistent with previous clinical observations that two drugs (pembrolizumab and nivolumab) against PD1 improved OS in patients with metastatic non-small-cell lung cancer \[[@CR35], [@CR36]\], recurrent or metastatic HNSC \[[@CR37], [@CR38]\], and recurrent or metastatic cervical cancer \[[@CR39]\]. These results suggested that TCR signaling pathway was associated with improved OS in 5 cancer types (BRCA, CESC, HNSC,genome, by fingerprinting each BAC and aligning overlapping BACs according to shared restriction fragment patterns. 2. Produce a highly accurate, complete genome sequence for Histoplasma capsulatum strain G217B with less than 1 error per 10000 nucleotides. The sequencing strategy used will entail a combination of paired-end plasmid and M13 sequencing reads from both whole genome shotgun and BAC-specific libraries. 3. Produce a reduced coverage (approximately 2-fold) genome sequence of the related Histoplasma capsulatum strain G186AR. The sequencing strategy used will entail paired-end reads from a whole genome shotgun library, with comparative assembly onto the existing G217B genome sequence. 4. Develop a microarray resource consisting of oligonucleotide sequences corresponding to each predicted gene in Histoplasma capsulatum strain G217B. Resulting arrays will be used to establish the relative expression level


dumping of the multiplicity, b) enhancement of the cummulative effect c) enhancement of heavy flavour production d) increase of the inelasticity.

The dumping of the multiplicity is a consequence of the overlapping of the strings forming a new one, in such a way, that the effective number of independent strings (clusters) is reduced compared to the number of original strings. The fragmentation of the new string can give rise to particles outside the kinematical limits of a nucleon–nucleon collision (the so called cummulative effect) and the shape of the x-distribution would be harder than the case of fragmentation of the original strings.

The new strings have also a larger tension due to the higher colour of the grouped partons located at the end of the string which is the SU(3)Q:

Remove [0] from getElementsByClassName

I'm trying to remove the [0] from the below and instead replace with iteration as appears to be the solution on another post here
However my knowledge is very limited so it may be that this is not the solution or a variation is needed.
The function is being called on on-click and I'm only looking for the element that is clicked to be activated.
For example if there are two occurrences of "thishere", only the occurrence which is clicked will be called.
Any help would be much appreciated.
function zxcv(el) {
    el.style.display = "none";
    el.parentNode.parentNode.getElementsByClassName("thishere")[0].style.display = 'block';
    return false;
}

A:

Just write a loop.
function zxcv(el) {
    el.style.display = "none";
    var elements = el.parentNode.parentNode.getElementsByClassName("thishere");


The Electronic Frontier Foundation announced Tuesday that Boing Boing's Cory Doctorow has been commissioned to tackle digital rights management technologies (DRM) that the rights group says threatens security, privacy, and undermines public rights and innovation.

The group said Tuesday that Doctorow, a vocal DRM opponent, is to become a special consultant for what the group is calling the Apollo 1201 Project, "a mission to eradicate DRM in our lifetime."

Doctorow, the EFF's former European affairs coordinator and current Boing Boing editor, said in a statement:

Apollo was a decade-long plan to do something widely viewed as impossible: go to the moon. Lots of folks think it's impossible to get rid of DRM. But it needs to be done. Unless we can be sure that our computers do what we tell them,TITLE: panic: sctp: no chunks on the queues

panic: No chunks on the queues for sid 5.
cpuid = 0
time = 382
KDB: stack backtrace:
db_trace_self_wrapper() at db_trace_self_wrapper+0x47/frame 0xfffffe0016ad96f0
vpanic() at vpanic+0x1e0/frame 0xfffffe0016ad9750
panic() at panic+0x43/frame 0xfffffe0016ad97b0
sctp_free_assoc() at sctp_free_assoc+0x32b3/frame 0xfffffe0016ad9850
sctp_timeout_handler() at sctp_timeout_handler+0x167f/frame 0xfffffe0016ad98e0
softclock_call_cc() at softclock_call_cc+0x1dd/frame 0xfffffe0016ad99b0
softclock() at softclock+0xa3/frame 0xfffffe0016ad99f0
ithread_loop() at ithread_loop+0x2f2/frame 0xfffffe0016ad9a60
fork_exit() at fork_exit+0xb0/frame 0xfffffe0016ad9ab0
fork_trampoline() at fork_trampoline+0xe/frame 0xfffffe0016ad9ab0
--- trap 0, rip = 0, rsp = 0, rbp = 0 ---
KDB: enter: panic
[ thread pid 12 tid 100018 ]
Stopped at      kdb_enter+0x6a: movq    $0,kdb_why


with a virulent *B. hyodysenteriae* strain \[[@CR20], [@CR21]\]. The use of DNA vaccines for SD has not been investigated in pigs. A *tlyA* mutant strain of *B. hyodysenteriae* has been examined for its use as a live attenuated vaccine. A 50% reduction in the number of animals developing clinical SD upon challenge with a virulent *B. hyodysenteriae* strain was demonstrated. However, there was no reduction in the number of animals that was colonised by the challenge strain \[[@CR22]\].

Despite all these efforts, an efficient vaccine against *B. hyodysenteriae* is currently not available. Recently, we isolated a weakly haemolytic *B. hyodysenteriae* strain which appeared to be less virulent than strongly haemolytic *B. hyodysenteriae* strains \[[@CR23]\]. In this study we explore this strain's vaccination potential by verifying its virulence in pigsTable [1](#Tab1){ref-type="table"}. Strength of haemolysis was determined as visible haemolysis of growth on blood supplemented culture plates and by in vitro quantification as described in a previous study \[[@CR23]\].Table 1***Brachyspira hyodysenteriae*** **strains, experimental set-up and results for faecal excretion and clinical signs of SD**Virulence trial number*B. hyodysenteriae* strainStrength of haemolysisModel and inoculation routeNumber of pigs positive for faecal excretion^a^Number of pigs with SD^a^18dIIStrongDirect oral inoculation2/62/62B204StrongDirect gastric inoculation5/95/9349StrongSeeder model5/144/144D28WeakDirect oral inoculation5/80/85D28WeakDirect gastric inoculation4/120/12Seeder vaccination experimentD28WeakDirect oral inoculation25/300/30^a^Given as proportion of total number of inoculated pigs.

For the virulence trials, strains were obtained from frozen stocks, thawed and grown on Tryptic Soy Agar (BD, Heidelberg, Germany), supplemented with 5% sheep blood (IMP, Brussels, Belgium) and 1% yeast extract (Oxoid, Aalst, Belgium) \[[@CR24]\]. Strains were subcultured twice and suspensions were prepared by harvesting a


multiple doses of the live strain were necessary. Obviously there are differences between the pathogenesis of *S. flexneri* infections and SD, as well as between the responses of their respective hosts. However, both bacteria share the niche of the colon and for both bacteria, serum antibody responses are not linked with protection. It has been demonstrated on several occasions that the number of animals that is protected against SD is significantly higher with increasing numbers of exposures to experimental challenge \[[@CR7], [@CR12]\] which would be in line with having a higher and prolonged mucosal immune response after multiple exposures.

The link between local IgA and delayed onset of SD opens perspectives for future vaccine development against *B.* *hyodysenteriae.* Some earlier studies of immunity induced by experimental infection of *B.* *hyodysenteriae* pointone of the essential factors to practice offsite construction. When units are constructed offsite and assembled later, contractors cannot afford to practice clash detection and resolution during assembly. It is irreversible, and even if corrected, such mistakes prove to be very costly for them in terms of time and costs.

A BIM services provider takes care of design modeling from pre-construction concept stages through to detailed offsite construction stages including assembling components for building or infrastructure construction project. Only approvals, planning and management are the disciplines that contractors now have to worry about.

More involvement of contractors in design coordination

Just a decade ago, most of the building construction and infrastructure projects were site-built, due to which contractors remained buried under tons of paper and struggled to manage their resources efficiently.

But


in batches or in bulk appropriate locations.

Bringing it altogether

It is likely that offsite construction will become widely accepted with each passing day. As construction companies grapple with newly emerging technologies as well as look for new opportunities for their profits, prefabrication or offsite construction is growing over them. Unless they want to be out of business in coming years, they should start looking for opportunities to improve their methods which are compatible with offsite construction methods – be it prefabrication of units, construction designs, and professional participation at every stage or construction planning.Explore your Bible.

Start right here and search in 4 English and many other Bible translations. Compare different translations side by side, write down your personal thoughts on Bible verses and let yourself be inspired.

Features

Unique Bible Selection

BibleServer offers a unique selection of modern and popular Bible translations. With more than 45 international translations, you'll find the Bible that's right for you.

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Many search options make it easier for you to find the Bible passage you are looking for. For example, you can search for subwords or in headlines and sort the result by relevance.

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To delve deeper into the Bible text, you can easily compare the different Bibles next to each other. You can even juxtapose individual verses.

Personal Notes & Likes

Personalize the Bible: Notes allow you to make


Leo Paquin

Leo Paquin (June 15, 1910 – December 2, 1993) was an American football player. He played end for Fordham University as part of the 1936 line known as the "Seven Blocks of Granite". After graduating from Fordham, he eschewed a professional football career in favor of a 40-year career as a high school football coach and teacher.

Biography
Paquin grew up in Brockton, Massachusetts, and he attended Fordham University where he played college football as an end. While there, he roomed with another Fordham lineman, Vince Lombardi. As a senior in 1936, Paquin played as the left end on the Fordham line known as the "Seven Blocks of Granite". That line was actually the second one to bear that name. Fordham University publicist Tim Cohane had first applied the     b+= " ";
            display.setText(b);
        }
        else
        {
            b+="";
            display.setText(b);
        }
    }

    else if (text.equals("C"))
    {
        b = "";

        display.setText(b);
    }
    else
    {


Background {#Sec1}
==========

Due to the global demographic and epidemiologic transitions, evidence for an increasing cancer burden over the next decades has emerged, particularly in low and middle income countries \[[@CR1], [@CR2]\]. The International Agency for Research of Cancer (IARC) reported in 2012 that lung, breast, and colorectal cancers (CRCs) were the most commonly diagnosed cancers, while lung, liver, and stomach cancers were the most common causes of cancer death \[[@CR3]\]. Globally, CRC was the third most common form of cancer \[[@CR3], [@CR4]\]. In Malaysia, according to the second report of the National Cancer Patient Registry (NCPR-CC), CRC was the second most common cancer after breast cancer \[[@CR5]--[@CR7]\].

Public health strategies that focus on reducing cancer incidences can benefit from comparing risk factors which have potential population-level impact \[[@CR8]\]. Behavioural riskanswers represent the information for the members of the household \[[@CR13]\]. Physical inactivity was defined as having a total physical activity level of less than 600 metabolic equivalents-minutes per week (METs-minutes*/*week) contributed by all three different life domains (work, travelling and leisure time) \[[@CR13], [@CR19], [@CR20]\]. Alcohol consumption in the NHMS IIII 2006 survey was regarded as a current drinker, which was defined as those who still consumed alcohol for the past 1 month prior to the survey \[[@CR13]\]. Obesity was defined as BMI 35--39.9 kg/mm^2^, while overweight was BMI 25--29.9 kg/mm^2^ and normal weight was BMI 18.5--24.9 kg/mm^2^ \[[@CR13]\].

Assuming a conservative latent period of 10 years between exposure/consumption of risk factors and diagnosis of CRC (i.e. the lag period for CRC development), it was better to use prevalence of exposure from population-based


    \setlength{\oddsidemargin}{-69pt}
                \begin{document}$$ PAF=\left[\mathrm{P}\left(RR-1\right)\right]/\left[\left[\mathrm{P}\ \mathrm{x}\ \left(RR-1\right)\right]+1\right] $$\end{document}$$

Where,

P = prevalence of exposure to the risk factor in total population;

RR = relative risk of risk factor and a specific cancer (CRC in this case).

### Estimation based on multiple risk factors {#Sec8}

Combined PAF for exposure to two risk factors *A* and *B* can be calculated by the following formula \[[@CR8]\]:$$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
       spaced apertures which are adapted to receive the corresponding clips or tabs of the back wall.
During assembly, the back wall is moved laterally towards the left side wall until the downturned tabs are received through the apertures and then the back wall is shifted downwardly a short distance so that the tabs clip over the lower edge of the openings. The right side wall is similarly engaged with the back wall except that the tabs on the right edge of the back wall project upwardly. In particular, the right side wall is moved laterally and then shifted downwardly until the upturned tabs engage the corresponding openings in the right side wall.
The front vertical edges of the side walls include vertical channels which open rearwardly and are adapted to


second embodiment uses a single sheet of foldable material such as metal which defines the bottom, side and back walls which are all joined together as a single integral piece. To form the box-like drawer, the side walls and back wall are foldable relative to the bottom wall about corresponding fold lines formed therebetween. Either drawer construction is usable within the above-described cabinet housing so as to define a complete knock-down vertical file cabinet which can be readily assembled.
Other objects and purposes of the invention, and variations thereof, will be apparent upon reading the following specification and inspecting the accompanying drawings.is when it comes to interplay of game mechanics
and narrative.

The game also explores various philosophical topics without shoving
(political) opinions down your throat better than any recently released
(western) game I've come across.

[https://www.youtube.com/watch?v=wJxNhJ8fjFk](https://www.youtube.com/watch?v=wJxNhJ8fjFk)

~~~
pdimitar
All true but it doesn't change the fact that it has fairly inconsistent
characters who swap traits all the time.

It also doesn't help that they are fairly typical anime archetypes which sadly
are often annoying.

Combine that with the occasional shock value quest that explains nothing
and... I quite like the game in the philosophy department but it's not that
great in several other aspects.

~~~
Pyrhos
>but it doesn't change the fact that it has fairly inconsistent characters who
swap traits all the time.

Mind elaborating on this? I haven't actually noticed any inconsistencies.

~~~
pdimitar
It's mostly 9S and 2B playing swapping the being curious and questioning
authority role. Most


to health insurers has had a strange side effect: It's going to lead to some people getting better deals on health coverage.

Now Avalere is out with some new numbers that follow the same trend: In almost every county using Healthcare.gov, people near poverty should be able to get a bronze plan, which covers about 60 percent of medical costs, for free.

It's a reminder to shop around. Sarah broke down yesterday the other things you need to know about open enrollment.

Kliff’s Notes

Your daily top health care reads, with research help from Caitlin Davis

News of the day

“Tax reform bill doesn't include repeal of Obamacare mandate, sources say”: “The House GOP’s tax reform bill set does not include a repeal of Obamacare’s individual mandate, despite a demand from President Trump. ThePhoto Gallery 4 Images

CENTRAL POINT, Ore. — Family members remember the man hit and killed by a car while crossing I-5 in Central Point on Thursday morning as a loving father who struggled with mental illness and substance abuse.

Investigators believe that 26-year-old Richard Drew Wilson of Eagle Point tried to cross the northbound lanes of I-5 near the Exit 33 interchange in Central Point around 6:15 a.m. on Thursday morning.

"Visibility in the area was limited by darkness and dense fog," said Oregon State Police (OSP).

Driving her Nissan Xterra northbound on I-5 and hampered by the conditions, 52-year-old Jeri Renee Wiggins struck Wilson in the northbound fast lane. The man was dead by the time emergency personnel arrived.

Those who knew Wilson — "Drew," as they knew him — say


to pleasure.' He trains
  himself, 'I will breathe out sensitive to pleasure.' [7] He trains
  himself, 'I will breathe in sensitive to mental fabrication.' He
  trains himself, 'I will breathe out sensitive to mental fabrication.'
  [8] He trains himself, 'I will breathe in calming mental fabrication.'
  He trains himself, 'I will breathe out calming mental fabrication.'
"[9] He trains himself, 'I will breathe in sensitive to the mind.' He
  trains himself, 'I will breathe out sensitive to the mind.' [10] He
  trains himself, 'I will breathe in satisfying the mind.' He trains
  himself, 'I will breathe out satisfying the mind.' [11] He trains
  himself, 'I will breathe in steadying the mind.' He trains himself, 'I
  will breathe out steadyingblue flowers. Echium candicans from Madeira, where it is known as the ‘Pride of Madeira’, is one of those. Other species are also grown here and cross breed with one another, producing an eclectic and unusual range of hybrid plants. Our most visually striking species is the true blue Echium gentianoides from La Palma, which produces large sky-blue flowers and smooth, grey-green leaves.

The Mediterranean Garden boosts a dazzling array of Echiums, each with a flower spike containing thousands of flowers with every shade of colour from sapphire blue to dusky pink. The result is a stunning floral explosion which resembles a natural firework display.

Chris Kidd, Curator – “Our display of Echiums in our Mediterranean Garden is simply stunning. Visitors are unlikely to see anything quite like it anywhere


wounded before the shooter took his own life at Sparks Middle School, east of Reno. The Associated Press reported that the incident was witnessed by 20 or 30 children.

"We have a lot of heroes today, including our children ... and our fallen hero, an amazing teacher," Washoe County School District Superintendent Pedro Martinez said.

Tim Robinson, deputy chief of the Reno police, also described Landsberry as "a hero."

Kyle Nucum, a 13-year-old student at Sparks Middle School, told NBC News that the suspect “was pointing a gun at the teacher after the teacher told him to put it down” before the first shot went off.

In a separate interview, Nucum told the Reno Journal Gazette that he heard “a pop, like a loud pop, and everybody was screaming.”

The school week atMolecular kinetic analysis of a local equilibrium Carnot cycle.
We identify a velocity distribution function of ideal gas particles that is compatible with the local equilibrium assumption and the fundamental thermodynamic relation satisfying the endoreversibility. We find that this distribution is a Maxwell-Boltzmann distribution with a spatially uniform temperature and a spatially varying local center-of-mass velocity. We construct the local equilibrium Carnot cycle of an ideal gas, based on this distribution, and show that the efficiency of the present cycle is given by the endoreversible Carnot efficiency using the molecular kinetic temperatures of the gas. We also obtain an analytic expression of the efficiency at maximum power of our cycle under a small temperature difference. Our theory is also confirmed by a molecular dynamics simulation.


and not have the interests of the travellers at heart," he said.

"I have also been told that these protesters on the site now outnumber the travellers."

He added: "The overwhelming number of callers to the council support our action and approach."

The cleared site would also be left so that it could not be re-entered, he said.

Essex Police said their presence at Dale Farm was intended to keep the peace and ensure anyone breaking the law was dealt with but no arrests had been made so far.

'Elderly and sick'

Supporters inside the site said they wanted Basildon Council to provide 62 plots to temporarily house those made homeless while planning permission was sought for other sites.

Image caption Travellers and campaigners have been protesting from a platform at the site

The council saidSite Mobile Navigation

Shortchanging Cancer Patients

Ezekiel J. Emanuel is an oncologist and former White House adviser who will be a professor of medical ethics and health policy at the University of Pennsylvania beginning in September. He will be contributing regularly to Op-Ed.

RIGHT now cancer care is being rationed in the United States.

Probably to their great disappointment, President Obama’s critics cannot blame this rationing on death panels or health care reform. Rather, it is caused by a severe shortage of important cancer drugs.

Of the 34 generic cancer drugs on the market, as of this month, 14 were in short supply. They include drugs that are the mainstay of treatment regimens used to cure leukemia, lymphoma and testicular cancer. As Dr. Michael Link, the president of the American Society of Clinical


reason for this is that cancer patients do not buy chemotherapy drugs from their local pharmacies the way they buy asthma inhalers or insulin. Instead, it is their oncologists who buy the drugs, administer them and then bill Medicare and insurance companies for the costs.

Photo

A patient receiving cancer treatment in Boston in 2008. Care is being rationed because of a dearth of the most effective drugs. Of the 34 generic cancer drugs on the market, as of this month, 14 were in short supply.Credit
Josh Haner/The New York Times

Historically, this “buy and bill” system was quite lucrative; drug companies charged Medicare and insurance companies inflated, essentially made-up “average wholesale prices.” The Medicare Prescription Drug, Improvement and Modernization Act of 2003, signed by President George W. Bush, put an end.......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... .......... ..........

Copyright © 2018 Albuquerque Journal

A new lawsuit filed on behalf of a local woman alleges that Santa Fe’s Christus St. Vincent Regional Medical was negligent twice while she was in the hospital in 2016.

The suit filed on behalf of Jamie Sams, a writer known for books on spirituality, says the hospital and a doctor who was treating her are to blame for Sams going into cardiac arrest.

And the negligence was compounded when hospital personnel resuscitated her, the lawsuit suit states.

ADVERTISEMENTSkip

................................................................

Reviving Sams violated her “do no resuscitate” directive, the lawsuit says.

Now Sams must live the rest of her life with pain and substantial medical bills, according to the suit filed in state


the water.

In the study, the scientists collected gooseneck barnacles—both isolated and in pairs—along with their fertilized eggs from Barkley Sound in British Columbia to take back to the lab so they could genetically analyze the paternal combinations. The DNA of the fertilized eggs revealed that none of the isolated barnacles had produced embryos through self-fertilization—so one hundred percent of these eggs must have been fertilized by capturing sperm from the water.

Surprisingly, though, even some of the barnacles that resided in pairs had embryos that had been fertilized with sperm from a non-neighbor. This left one possibility: that the barnacles release their sperm into the ocean and let the water carry it to distant neighbors. This type of fertilization has been observed in other marine animals that can’t orand a nuclease protection assay gave evidence of a cardiac-specific protein-DNA interaction in this region. Deletion analysis indicated that a hybrid gene with 1205 bp but not 1054 bp of upstream DNA directed FGF16 promoter activity in transfected neonatal rat cardiac myocytes. We identified a putative myocyte enhancer factor 2 (MEF2)-binding site at nucleotides -1159/-1148, confirmed by electrophoretic mobility shift assay and MEF2 antibody binding. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes. These data suggest that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart.


full of tears!"
myArray[1] = " I knew I would miss my American friends very much.All the best to you "
myArray[2] = ""

A:

.+?([!?.](?= |$)|$)

should work.
It will match any sequence of characters that are either

followed by a punctuation sign that is itself followed by a space or end-of-string, or
followed by the end of the string.

By using the reluctant quantifier +?, it finds the shortest possible sequences (=single sentences).
In JavaScript:
result = subject.match(/.+?([!?.](?= |$)|$)/g);

EDIT:
In order to avoid the regex splitting on "space/single letter or multidigit number/dot", you can use:
result = subject.match(/( \d+\.| [^\W\d_]\.|.)+?([!?.](?= |$)|$)/g);

This will split

I left the United States with my eyes
  full of tears! 23. I knew I would miss
  my American friends very much. I. All
  the best to you.

into
I left the United States withwhat they are trying to achieve by going through each row and column. At what point would they consider their visit to this page a success? How can your product get the user there quicker and minimise their workload?
If you find that actually there is a need for the table then maybe consider the following things:
Look at the ability to show and hide columns.
In most cases when you are looking at data you rarely need every single column available to gain the information you are looking for. This also allows you to free up some screen estate, where 10 columns is a nice to have, maybe only 1% of your users actually need it. 99% may only need to see 3 columns, so offer to ability to


adenylate kinase (ADK),^[@ref37],[@ref38]^ DNA Y-family polymerase IV (DPO4),^[@ref39]^ lipase 1 (LIP1),^[@ref40],[@ref41]^ and phosphonate-binding protein (PhnD).^[@ref42]^ As shown in [Figure S1](http://pubs.acs.org/doi/suppl/10.1021/acscentsci.8b00274/suppl_file/oc8b00274_si_001.pdf), these proteins are with different sizes and different motions between open and closed states. We will quantify the intrinsic global energy landscape as well as the intrinsic local open--closed conformation energy landscape from the underlying DOS extracted from the conformational dynamics simulation, by applying the two-basin structure-based model. The topography of the conformational landscape for each individual protein can be represented by the dimensionless ratio Λ between the energy gap between the native (closed) state and the average non-native states (*δE* = \|*E*~n~ -- ⟨*E*~non--native~⟩\|), the roughness of the conformation energy landscape or the width of the energy distribution of the non-native states (*δE*), and the size ofThis shows a clear funneled intrinsic energy landscape toward the native closed state. In general, free energy depends on the energy, entropy or DOS, and temperature (*G* = *H* -- *TS*). As a result, at low temperature, the effect of energy contributes to the closed basin on free energy landscape; at intermediate and high temperature, the effect of entropy leads to the open and unfolded basins on free energy landscape.

![Logarithm of open--closed (A) and global (B) DOS of the 5 different proteins as a function of *Q* and energy. Here, *Q* is calculated as the fraction of native closed contacts for panel A and native global contacts for panel B.](oc-2018-00274k_0001){#fig1}

![Average energy of intrinsic local conformation energy landscape as a function of *Q*~closed~ and RMSD~open~ of LIP1 (A), DPO4


[Supporting Information](http://pubs.acs.org/doi/suppl/10.1021/acscentsci.8b00274/suppl_file/oc8b00274_si_001.pdf)). This relationship may have something to do with the parameters of the model. Similar results have been reported in previous studies.^[@ref35]^ This correlation may decrease or disappear if we continuously change the parameters of one protein system. However, the correlation between energy landscape topography and the crucial characteristics of proteins is independent with the parameters of the simulation model.

Methods {#sec3}
=======

The two-basin coarse-grained structure-based model (SBM)^[@ref12],[@ref55],[@ref56]^ for each selected protein was constructed, on the basis of the open and closed reference structures of each protein in the Protein Data Bank (all the PDB IDs used in the simulations are listed in [Table S1](http://pubs.acs.org/doi/suppl/10.1021/acscentsci.8b00274/suppl_file/oc8b00274_si_001.pdf)). The simulation details and analyses are introduced in the [Supporting Information](http://pubs.acs.org/doi/suppl/10.1021/acscentsci.8b00274/suppl_file/oc8b00274_si_001.pdf).

Conclusion {#sec4}
==========

Intrinsic movements within a protein, such as large-scale domain--domain open--closed conformation transitions, areenergy field from the light-emitting diode for purposes of determining the pilot""s aimpoint within the display.
U.S. Pat. No. 4,565,999 issued Jan. 21, 1986 to King discloses a cursor control system for use with a data terminal wherein a radiation source and a radiation sensor are used to determine changes in a user""s head position for purposes of controlling cursor position on the screen.
U.S. Pat. No. 4,567,479 issued Jan. 28, 1986 to Boyd discloses a directional controller for video or computer input by physically-impaired users consisting of a series of mercury switches disposed in proximity to a user""s head, wherein movements of the user""s head are sensed and converted into cursor control commands. This device also employs a pressure switch activated by the user""s mouth which can provide a


of the virtual computer display by users with arbitrary, non-central preferred retinal loci.
It is still another advantage of the present invention that it alerts the user to events occurring outside of the user""s instantaneous field-of-view through the use of spatialized audio alerts perceived to originate from the direction of the event, thus causing the user to turn and look in the direction of the event.
It is yet a further advantage of the present invention that it provides effective operation at magnifications much greater than those possible using fixed monitors, by using a novel technique known as spatial compression.
It is still another advantage of the present invention that it provides improved scrolling of imagery across the user""s field-of-view, through application of smoothing, thresholding, prediction, and drift compensation algorithms to0xC, 0x2, 0xA, 0x6, 0xE,
    0x1, 0x9, 0x5, 0xD, 0x3, 0xB, 0x7, 0xF
  };
  return t[b >> 4] | (t[b & 0xF] << 4);
}

void RevBytes(unsigned char* b, size_t c)
{
  size_t i;
  for (i = 0; i < c / 2; i++)
  {
    unsigned char t = b[i];
    b[i] = RevByte(b[c - 1 - i]);
    b[c - 1 - i] = RevByte(t);
  }
  if (c & 1)
    b[c / 2] = RevByte(b[c / 2]);
}

int main(void)
{
  int i;
  unsigned char buf[16] =
  {
    0x0, 0x8, 0x4, 0xC, 0x2, 0xA, 0x6, 0xE,
    0x1, 0x9, 0x5, 0xD, 0x3, 0xB, 0x7,


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gf has cramps gives her chocolate and rubs her stomachin colonic epithelial cells from IBD patients, and this elevation can be induced by TNF-α.^[@bib23]^ We confirmed that TNF-α alone increased CCL20/MIP-3α, but a significant synergistic effect was observed upon adding IL-22, IL-17A, and TNF-α simultaneously after 24 and 48 h of stimulation ([Figure 3b](#fig3){ref-type="fig"}).

IL-17F, IL-21, and IL-26 are also secreted by Th-17 cells,^[@bib17]^ and IL-21R and IL-26R are expressed by HT-29 cells.^[@bib24],\ [@bib25]^ We tested the ability of these three cytokines to increase the expression of the candidate biomarkers in the presence of IL-17A, IL-22, and TNF-α. None of them was essential for biomarker expression ([Supplementary Figure S5](#sup1){ref-type="supplementary-material"}).

Taken together, these results show that S100A8/A9, PAP, LCN2, DMBT1, and CCL20/MIP-3α are regulated by IL-17A, IL-22, and TNF-α in human epithelial cells.

Expression of potential IL-23-associated biomarkers in patients with Crohn\'s


some people recommend using use-cases for describing the manual process. Whether that is the most efficient way to capture that information is debatable. It might be the best approach if the people currently using the manual system will only be available for a short time at the beginning of the project so you need to capture as much info from them as possible at that time OR if you are flowing the process onto yet another company to actually build.
I would start with doing use-cases for the system being built and then fill out the details by figuring out what the manual system does. That would be the most efficient approach and will likely be sufficient for most projects.

on." "Can i bring martha and the kids over here?" "Over here?" "We're sitting ducks over there- no protection at all." "Oh, jerry." "You can use our basement." "Your basement?" "What about your shelter?" "It's the only place we can survive!" "I don't have any room, jerry." "There's not near enough room or supplies." "It's designed for three people." "Well, we'll bring our own food and water." "We'll sleep standing up." "Bill, you've got to help me." "You've got to keep my family alive." "We won't use any of your stuff." "What about air?" "That's a 10x10 room, jerry, with an air filter designed for three people." "Will you bring your own air?" "Well, just give us a chance." "No, no, no." "48 hours, bill, then we'll get


"You're wasting precious time you could use for figuring out how you can survive." "Why don't we get some kind of battering ram?" "Yeah, let's go to bennett avenue." "Phil klein has some heavy pipe in his basement." "No, no- that would get him into the act, too, and who cares about saving him." "If we do that- if we let all those people know about the shelter on our street- we'd have a whole mob to contend with." "A whole bunch of strangers." "What right have they got to come over here?" "This isn't their street." "This isn't their shelter." "Oh, oh, this is our shelter, huh?" "And on the next street, that's another country." "Patronize home industry." "You idiots, you fools, you're insane." "All of you."/*
 *
 * Copyright 2015 gRPC authors.
 *
 * Licensed under the Apache License, Version 2.0 (the "License");
 * you may not use this file except in compliance with the License.
 * You may obtain a copy of the License at
 *
 *     http://www.apache.org/licenses/LICENSE-2.0
 *
 * Unless required by applicable law or agreed to in writing, software
 * distributed under the License is distributed on an "AS IS" BASIS,
 * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 * See the License for the specific language governing permissions and
 * limitations under the License.
 *
 */

#include <string.h>

#include <grpc/support/alloc.h>

#include "src/core/lib/json/json.h"

grpc_json* grpc_json_create(grpc_json_type type) {
  grpc_json* json = (grpc_json*)gpr_zalloc(sizeof(*json));
  json->type = type;

  return json;
}

void grpc_json_destroy(grpc_json* json) {
  while (json->child) {


        = 0x2
)

// Errors
const (
	E2BIG           = syscall.Errno(0x7)
	EACCES          = syscall.Errno(0xd)
	EADDRINUSE      = syscall.Errno(0x30)
	EADDRNOTAVAIL   = syscall.Errno(0x31)
	EAFNOSUPPORT    = syscall.Errno(0x2f)
	EAGAIN          = syscall.Errno(0x23)
	EALREADY        = syscall.Errno(0x25)
	EAUTH           = syscall.Errno(0x50)
	EBADF           = syscall.Errno(0x9)
	EBADRPC         = syscall.Errno(0x48)
	EBUSY           = syscall.Errno(0x10)
	ECANCELED       = syscall.Errno(0x58)
	ECHILD   Introduction {#s1}
============

Androgenetic alopecia (AGA) is the most common cause of hair loss in men. It is an androgen-dependent dermatological disorder, in which an alteration in the hair cycle dynamics leads to vellus transformation of terminal hair follicles ([@B9]). Due to the limited treatment options, searching for alternative treatment therapeutics in AGA has been a continuous mission for scientists in the field.

The hair follicle undergoes cycles of renewal in three phases known as anagen, catagen, and telogen. Each new cycle enables the development of the hair follicle from an active hair shaft production stage (anagen) to quick involution (catagen) and finally, to resting (telogen) stages. The development of these phases involves intensive organ remodeling, especially during the anagen phase when the growing follicle migrates downwards through the dermis, and


{#s2_4}
-------------------------------

In order to describe Ki67-positive hair matrix cells in mouse hair follicles, immunohistochemistry was performed on 5-µm-thick, paraffin-embedded skin tissue sections. The sections were deparaffinized in xylene, and rehydrated by a series of graded ethanol rinses. After antigen retrieval in sodium citrate buffer, endogenous peroxidase activity was blocked with 10% bovine serum for 2 hours, followed by incubation overnight at 4°C with rabbit anti-Ki67 (Abcam, Cambridge, UK; No.: ab15580, 1:500) primary antibody. Subsequently, horseradish peroxidase conjugated secondary antibody (Service Bio, GB23303, 1:200) was pipetted on the sections and incubated for 30 minutes at 37℃. The negative control was subjected to the same steps as described above, but the primary antibody was replaced by 10% bovine serum. With diaminobenzidine (DAB), the reaction product was visualized as brown staining. Then,hair grow scoring system ([@B32]). It was found that Jagged1 and EGF tended to partially reverse testosterone-suppressed hair growth, however, the revision was not significant statistically. In the presence of both the bioactive factors (Jagged1 + EGF), the hair growth score was increased to the level that was significantly higher than that of the testo group (p \< 0.05), and not different from the non-testosterone positive control ([**Figure 2B**](#f2){ref-type="fig"}).

![Influence of Jagged1 and/or EGF on hair growth. Mice were treated for 14 days with the indicated treatments, after which the mice hair regrowth were recorded. **(A)** Images of hair growth at day 0, 7, and 14, respectively. **(B)** Hair growth score. Data represent the mean ± SEM of five animals. Different letters denote statistical differences between groups (p \<