little electronic help finding our way.He said no. Absolutely not. In his view, it's hard enough to ask a person for directions, much less take directions from a box with a voice. So...I'll pack a U.S. map and look for an updated state highway map (free, if possible) as we enter each state and try out their rest stops.He'll also print out a Mapquest for each day's plan before we leave home. The plus side of this is that we'll also print out a Braille copy of the route, and Amigo can do his part to help navigate. White cane and all, our teen will be an active participant in the road trip. He's a great believer in the slogan that getting there is half the fun!But thenagain, the Mapquest I printed for today's music festival landed me and my minivan in the elementary school's turnaround for parents instead of in the high school's parking lot four full blocks away.... just goes to show you, there's always something.

4 Comments:

Mapquest sucks. You should continue to try talking your husband into the GPS unit. My mom and dad had one when I travelled with them to California last summer and it got us everywhere we needed to go all over Santa Barbara. It's not difficult to follow the directions at all, it goes one turn at a time and doesn't overwhelm you with a bunch of directions at once. Good luck!

Oh what fun! We stop for state maps every time we see a welcome center. but we


rate of 3.7% (95% CI 0.9-8.3%), which was not significant. The corresponding odds ratios were significantly increased for monetary incentives (1.36; 95% CI 1.30-1.88), and when abridging the questionnaire (1.15; 95% CI 1.01-1.31). However, partial nonresponse and treatment outcome were independent of the two factors. Incentives and a shorter questionnaire led to higher return rates but did not affect partial nonresponse and self-report of treatment outcome in a randomized postal survey.Q:

Simple fft to Gaussian pulse with MATLAB

trying simply to create femtosecond pulse in MATLAB exactly like in the attached image,

the carrier frequency is around 374THz, and my sampling frequency is 10 times the carrier.
The results of the fft yields nothing understandable... tried to change some of the variables, fs,t-around zero, fftshift...
but could not conclude what's wrong with code.
my code follows matlab fft example :
clear all ; close all ; clc
f=374.7e12;%Thz
fs=f*10; %sampling frequency
T=1/fs;
L=1000;
sigma=5e-15;
t=(0:L-1)*T; %time base

x=(exp(-(t-50e-15).^2/(2*sigma)^2)).*exp(-1i*2*pi*f*t);
subplot(2,1,1)
plot(t,real(x),'b');
title(['Gaussian Pulse \sigma=', num2str(sigma),'s']);
xlabel('Time(s)');
ylabel('Amplitude');
ylim([-1 1])
xlim([10e-15 90e-15])

NFFT = 2^nextpow2(L);
X = fft(x,NFFT)/L;
Pxx=X.*conj(X)/(NFFT*NFFT); %computing power with proper scaling
f = fs/2*linspace(0,1,NFFT/2+1); %Frequency Vector

subplot(2,1,2)
plot(f,2*abs(X(1:NFFT/2+1)))
title('Magnitude of FFT');
xlabel('Frequency (Hz)')
ylabel('Magnitude |X(f)|');

the results are :

A:

You simply don't plot what you want to see. Note that your time domain signal is complex-valued and you modulate by a negative frequency. So


the range of frequencies where things are happening are the negative frequencies (or - by periodicity - the frequencies in the range $[f_s/2,f_s]$), but those you don't plot. If you change the definition of your frequency vector and the corresponding plot command you'll see what you expect to see (i.e. a Gaussian in the frequency domain centered at $f_s-f=3.37e15$ Hz):
f = fs*linspace(0,1,NFFT); % (full range) Frequency Vector
...
plot(f,2*abs(X))

OR, simply change the negative modulation frequency to a positive one
x=(exp(-(t-50e-15).^2/(2*sigma)^2)).*exp(1i*2*pi*f*t);

and leave everything else unchanged. Then the Gaussian in the frequency domain is centered at $f=374.7$ THz. This is probably what you expected to see in the first place.

Q:

php mailer script error 5

This is my code and i have done everything to make it work but i am stuck. I can't get this code to sent email out ..
<?php
if(isset($_REQUEST['submit']))
{
$to  =  "usman_86@rocketmail.com";
$subject = "Find Dealer @ flowsleeve";
$headers = "From: Find Dealer ";
$headers .= "Reply-To: ". strip_tags("usman_86@rocketmail.com") . "\r\n";
$headers  = 'MIME-Version: 1.0' . PHP_EOL;
$headers .= "Content-Type: text/html; charset=ISO-8859-1\r\n";
$messsage = "
 Name             : ".$_REQUEST['first_name']."
Email            : ".$_REQUEST['email']."
Event Type       : ".$_REQUEST['event_type']."
Event location   : ".$_REQUEST['event_location']."
Last Name        : ".$_REQUEST['last_name']."
Home Phone       : ".$_REQUEST['home_phone']."
Event Date


Q:

transfer javascript var created with 'passport' to express router

i created this passportAuth.js file fo authentication:
module.exports = function(passport, FacebookStrategy, config, mongoose, fbgraph){

passport.serializeUser(function(user,done){ //make the user reference available threw multiple pages
    done(null,user.id);
});

passport.deserializeUser(function(id,done){
    userModel.findById(id, function(err, user){
        done(err, user);
    })
})

passport.use(new FacebookStrategy({
    clientID: config.fb.appID,
    clientSecret: config.fb.appSecret,
    callbackURL: config.fb.callbackURL,
    profileFields: ['id', 'displayName', 'photos', 'birthday', 'events', 'profileUrl', 'emails', 'likes']
}, function(accessToken, refershToken, profile, done){

    var fb = new fbgraph.Facebook(accessToken, 'v2.2');
    fb.me(function(err, me) {
        console.log(me);
    });
    fb.my.events(function(err, events) {
        console.log(events);
   'photos', 'birthday', 'events', 'profileUrl', 'emails', 'likes']
}, function(req, accessToken, refershToken, profile, done){
    req.tmpPassport = {};
    var fb = new fbgraph.Facebook(accessToken, 'v2.2');
    fb.me(function(err, me) {
        req.tmpPassport.me = me;
    });
    fb.my.events(function(err, events) {
        req.tmpPassport.events = events;
    });
    fb.my.friends(function(err, result){
        req.tmpPassport.results = results;
    });

}))


Take a few seconds to be safe.

Do You Have a Reinforcement Bracket? Some do-it-yourselfers neglect to install an opener reinforcement bracket to the top section of the door. Failure to do so can damage your door. Do-it-yourselfers should check the installation manual for specific instructions.

Get a More Powerful Opener? If your door feels heavy or requires two hands to open it, the door is probably out of balance and needs adjustment. A variety of problems can cause this, and if you try to fix it yourself, you could get hurt. Call a local trained door systems technician to diagnose the problem and offer a solution. The answer is not a more powerful garage door opener. Openers are designed to open doors that are properly balanced.

Sensitivity Training. Garage doorSharks, we were all just people trying to make a difference in our country. People simply wanting to do good. People, who, at the end of the day, just wanted the America they lived in to most closely reflect their own personal ideals.

But now? Now I’m scared of the America some people want to live in.

With talks of walls, deportations, limiting the rights of women and the LGBTQ community, and a willingness to (happily) fire off nuclear weapons, the America proposed by the Republican party reads more like something out of a George Orwell novel than a 21st century American campaign platform.

How the GOP has gone from a party that once promoted civil liberties and American exceptionalism to one that promotes hatred, racism, bigotry, sexism, and the close


1. Field of the Invention
The present invention relates to a method for suppressing formation of deposits on a fuel injector and a device for injecting fuel.
2. Description of the Related Art
Japanese Unexamined Patent Publication No. 62-103456 discloses a fuel injector for an internal combustion engine, having a radiating member with a high thermal conductivity, to prevent the temperature of the nozzle holder from being higher, to thereby prevent the evaporation of fuel in the nozzle holder. In general, the nozzle holder should have a durability to ensure the precise control of the fuel amount to be injected, and thus should be formed of a material with a low thermal conductivity. Therefore, this fuel injector is additionally provided with the radiating member with a high thermal conductivity to keepseries. "We watched a lot of actors when we were shooting Friends years ago, and a lot of actors would come from film—guest stars—and they were scared," she said. "It was a scary arena to be in front of a live audience. Comedy is nothing other than being truthful and honest, but just with crazy, odd circumstances behind it."


decrease in interest rates, soaring share prices, salary hike, etc.

Here, mymoneykarma has listed several points that may help you in figuring out the best time to buy your dream home:

Are You Single?

Often, events such as marriage and childbirth are the triggers that lead people to purchase homes. This is quite ironic, as being single is the perfect time to take mortgages and build an asset. It is so because you don't remain overburdened with too many responsibilities at this stage.

Do You Have a Budget?

If you have an annual income that easily lets you pay monthly EMIs and other expenses as well as make savings to assist in downpayment, it indicates a green signal. Go ahead with your plan of turning your dream into a reality.

In case you arethat CAA (cancer-associated adipocytes) and CAF (cancer-associated fibroblasts) derived exosomes could increase chemoresistance by transporting microRNAs to surrounding cancer cells \[[@CR35]\]. Miharu Kobayashi et al. found that significantly less let-7 family miRNA was expressed in high invasive cells (SKOV-3), but was highly expressed in exosomes. Within a tumour, high invasive tumour cell derived exosomes signal low invasive tumor cells and low invasive tumour cell derived-exosomes can signal high invasive tumour cells to increase invasion of recipient cells \[[@CR41]\]. This suggests that the exosomes plays an important role in the tumour microenvironment and OvCa metastasis.

Roles in ovarian cancer therapy {#Sec8}
===============================

Exosome-related immunotherapy {#Sec9}
-----------------------------

Exosomes are known to contribute to immunosuppression and tumour immunity escapes \[[@CR54]--[@CR56]\]. A previous study indicated that depletion of peritoneal macrophages by clodronate could reduce ovarian tumour progression


does not require large and expensive equipment \[[@CR81]\]. This method is also highly flexible and can be adopted for analyses of various downstream bioactive substances, such as DNA, RNA and proteins.

Conclusion and future perspective {#Sec17}
=================================

Exosomes play a crucial role in multiple pathophysiological procedures, such as inflammatory response, immunoregulation, tumorgenesis, tumor invasion and metastasis. Many new findings and new hypotheses suggest the need for further research, as exosomes have great diagnostics and therapeutic potential, yet many questions remain. New methods have been explored to isolate exosomes efficiently and purely, and future studies will need to make comprehensive comparisons of these methods. Multi-Omics, such as the high-throughput expression analysis technique, will reveal critical molecules and mechanisms for the packaging of cargos.

Exosomes have shown immense potential in the early diagnosis, drugworkshop.

For Renwick, the equation must factor in the loss of cargo business that goes elsewhere to avoid the extra costs now associated with Los Angeles/Long Beach.

“If you care about global greenhouse emissions, you probably don’t want the ports of Los Angeles and Long Beach to lose cargo,” Renwick said.

Ships going to New York or other ports, he said, will face fewer clean air restrictions than they do here, and because of that, will pay less for shipping.

“Everyone who comes up and speaks seems to think there’s a simple and clear answer,” he said. “But we are charged with looking at the problem holistically, and it’s a bunch of trade-offs, many of which can’t be measured.”

The new, clean trucks also are expensive and near-zero models are not being made


upon applies only to actions of the court in vacation. Furthermore, the transcript is a reproduction of the court record, which would not necessarily reflect signatures on an original judgment.
The judgment is affirmed.
We agree. HARRIS, C. J., and BYRD and HICKMAN, JJ.
that we're seeing each other in Paris, but we may," Trump said. "There may be a lunch for the leaders."

The White House and the Kremlin had previously considered a formal meeting in Paris. That now seems more likely for later this month, when they attend the Group of 20 summit of international leaders in Argentina.

Trump and Putin have met previously on the sidelines of two summits and had their own bilateral meeting in July in Helsinki. At that meeting, Trump would not say whether he believed Putin or U.S. intelligence agencies about their conclusions about Russia's interference with the 2016 presidential election.

Trump's brief visit to Europe comes amid uncertainty about the U.S. relationship with the continent. Trump has railed against trade deals with the European Union and has


treatment approaches, especially for adult patients. The aetiology of AN is still unclear, however neuroscientific research has contributed to the development of theoretical models of the illness, linking the core symptoms of AN such as restrictive eating to alterations in brain circuits \[[@CR1]--[@CR4]\].

It has been suggested that neuropsychological deficits mediate between underlying neurobiological functioning and the symptom and behaviors that we see in these patients \[[@CR5]\]. Neuropsychological studies have repeatedly demonstrated significant deficits in executive functions such as set-shifting, central coherence and decision-making. Set-shifting refers to the ability to move back and forward between different tasks or mental sets, and is often used as a measure of cognitive flexibility. Patients with AN often have a rigid thinking style, which also involves eating and weight. These patients also often{#Sec4}
=======

Search strategy and selection of studies {#Sec5}
----------------------------------------

Relevant literature was identified via searches in PubMed, PSychINFO and Embase databases using the search terms \[anorexia nervosa\] AND \[recovered OR recovery OR mental health recovery\] AND \[set shifting OR central coherence OR decision making\].

In total, the main search resulted in 158 articles. A supplemental search was performed by a manual search in Google Scholar, which resulted in five studies. After removal of duplicates, a total of 86 articles were assessed for eligibility. Studies were included if they met the following inclusion criteria:Study included an AN-REC or an AN weight recovered (AN-WR) sample and comparison with a healthy control group/normative scores.Manuscript written in English.Study published in peer-reviewed journals.Abstracts and titles were screened for relevance and eligibility, and 57 articles were excluded. The


majority of studies found poorer set-shifting in AN-REC compared to healthy controls \[[@CR9], [@CR10], [@CR14]--[@CR16], [@CR22], [@CR24], [@CR26], [@CR28]\]. They demonstrate that set-shifting difficulties persist after recovery, and that AN-REC does not differ from acute AN patients. Results from two of the studies showed a trend towards poorer set-shifting, but the findings were not significant \[[@CR30], [@CR31]\]. Similarly, one study found some evidence for poorer set-shifting in AN-REC \[[@CR21]\]. Four studies reported no differences between AN-REC and healthy controls, suggesting that there are no set-shifting difficulties in recovered patients \[[@CR11], [@CR12], [@CR18], [@CR20]\].

Central coherence {#Sec9}
-----------------

Most studies used the Rey Complex Figure Test (RCFT) to investigate central coherence, but also the Embedded Figures Test, Sentence Completion Task, Homograph Reading Task, National Adult Reading Test and Fragmented Pictures Task wereskilled at detailed processing and that weak central coherence may be a factor that perpetuates eating disorder behavior. They also suggest that cognitive style could be a trait of the illness \[[@CR24]\].

Lindner et al. \[[@CR27]\] did not find any inefficiency in global processing in the recovered group. Similarly, Talbot et al. \[[@CR9]\] did not find any differences in measures of local and global processing. Therefore, based on the existing literature, caution should be made when determining whether central coherence is related to state or trait of AN.

Decision-making is a complex construct, and few studies have investigated decision-making in AN-REC. However, according to the existing studies, it may seem like AN-REC does not have difficulties with decision-making tasks. In a study using the IGT, Tchanturia et al. \[[@CR17]\] found


that have problems with set-shifting which could be independent from AN diagnostic subtype, a topic in need of further investigation.

Other differences in study design, such as sample size, might also affect the results. Lack of power calculations estimating the sample size necessary to detect significant differences between groups, could contribute to conflicting findings. In the current review, studies within the central coherence domain showed various findings. One study that failed to find significant results had a sample size of fifteen in the AN-REC group. In addition, conflicting findings could also be reflected by the large variety of tests that have been used within the same cognitive domain.

An important area of research is focused upon which factors that distinguish adolescent patients from adults. Adolescents seem to have a betterinformation {#FPar1}
====================

TSF has a PhD in Psychology from the University of Oslo and has previously worked at the Regional Department for Eating Disorders at Oslo University Hospital. She is currently in a postdoctoral position in Møre and Romsdal Hospital Trust located in Molde, Norway.

This study was funded by Møre and Romsdal Hospital Trust in Norway.

Not applicable.

Not applicable.

Not applicable.

The author declares that she has no competing interests.


further in embracing homosexuality as a sexual orientation that is designed and bestowed by God. It suggests that Francis does not believe that individuals choose to be gay or lesbian, as some religious conservatives argue.

Austen Ivereigh, who has written a biography of the pope, said Francis had likely made similar comments in private in the past, when he served as a spiritual director to gay people in Buenos Aires, but that Cruz’s public discussion of his conversation with Francis represented the most “forceful” remarks on the subject since 2013.

It did not, however, represent a shift in church teaching, Ivereigh said, since the church had never formally made any pronouncements on why individuals were gay.

Christopher Lamb, the Vatican correspondent for the Tablet, said the comments were remarkable and aThe mutation gene mutation identified in this patient, c.334A\>G (p.Thr112Ala), was previously reported to be associated with the adult-onset Krabbe disease phenotype but was combined in a compound heterozygous genotype with another mutation, c.592G\>A (p.Glu198Lys) \[[@b9-amjcaserep-20-643]\]. To the best of our knowledge, this is the first report to describe the phenotype of infantile Krabbe disease associated with the homozygous mutation c.334A\>G (p.Thr112Ala). The effect of the p.T112A and p.I562T mutations on galactocerebrosidase enzyme activity was previously evaluated by Luzi et al. who published the findings from a functional study that showed a significant reduction in the activity of the enzyme in COS-1 fibroblast-like cells *in vitro* that were transfected with pcDNA3 for both mutations \[[@b10-amjcaserep-20-643]\].

In this case report whole exome sequencing (WES) and whole genome sequencing (WGS) was


Metadata

A notion pregnant with such trepidation that it makes Joan Allen almost pull off a Rose Madder or a Dolores Claiborne or a Jessie Burlingame from Stephen King‘s Gerald’s Game (now also a feature film), with Anthony LaPaglia and Stephen Lang playing the typical King husband and retired detective-hound, respectively.

If it weren’t for King’s clunky – by his own standards – script based on his own, brilliant, short story; Peter Askin‘s lacklustre direction had all the potential of going down in history as one of the cringeworthy adaptations of a King story. But that isn’t the case here; A Good Marriage entertains just enough as you keep noticing the words from the book being acted out and spoken by the performers; all very well. This pilgrim was sorted.

Andthe geometry resolution forces the use of much finer space discretization than that is needed to solve for waves away from material irregularities or interfaces. This problem is firstly investigated in the paper in SPEM framework, in order to determine the largest allowed time increment. Moreover, in technical literature, a great interest is addressed in finding numerical schemes which allow computational advantages together with unconditional stability [@bib_14; @bib_32; @bib_36; @bib_37; @bib_38]. Otherwise, an alternate implicit direction method is proposed for the time evolution of the electromagnetic field in the SPEM framework by preserving the leapfrog marching on in time of the explicit integration scheme. By considering a 2-stage splitting approach, the leapfrog implicit formulation is carried out by suitably handling the formulas related to two adjacent time steps.


improving the conventional SPEM algorithm. The paper is organized as follows. In section 2 basic ideas on smoothed particle hydrodynamics method are recalled in order to provide the original SPEM numerical scheme in solving time-domain Maxwell’s curl equations. Investigations about the stability criterion are also included. In section 3 the LAF-SPEM method is described and simulation results are reported and discussed in section 4 also by comparing with standard FDTD computations and existing exact solution. A brief conclusion complete the paper.

The original smoothed particle electromagnetics method
======================================================

The SPH scheme has been adopted by the authors to compute the time-domain Maxwell’s curl equations by using particle approximation, so obtaining SPEM method [@bib_1; @bib_2]. For the reader convenience, a brief summary of SPEM fundamentals is reported in the following. Let considermight be due to virally induced neuroinflammation, we used a well-defined animal model in which the pro-inflammatory viral Tat protein is expressed exclusively within the central nervous system (GFAP-driven, doxycycline-inducible HIV-1 Tat transgenic (Tat-tg) mice \[[@B14]\]). To confirm our findings, we also used a second experimental animal model, in which wild-type mice were exposed acutely to HIV-1 Tat by direct intracerebral injection (Tat-ICI; \[[@B15]\]).

We explored the cerebrovascular response of these animals to a defined hypercapnic stimulus, by measuring changes in CBF over the somatosensory cortex using laser Doppler flowmetry, in combination with two-photon in vivo imaging of cortical vessels. We found a significant loss of normal responsiveness to hypercapnia in Tat-exposed mice, relative to controls. This pathology was initially revealed by a long (5 minute) exposure to moderate


CO~2~ was added to a 21% O~2~ air mixture for either 5 minutes or 30 seconds; CBF was then recorded for a total of 9 or 5 minutes, respectively.

Two-photon microscopy
---------------------

### Examination of pial arterioles

Urethane/xylazine anesthetized mice were securely placed into a stereotactic frame and a thin skull window was created as described in \[[@B34]\]. To visualize blood vessels, Texas Red-dextran (MW 70 kDa, Life Technologies, Invitrogen, Grand Island, NY, USA) was injected intravenously (10 mg/kg, in 0.1 ml of saline) into the right femoral vein. Arterioles were identified by the intrinsic auto-fluorescence of smooth muscle (as visualized using a 480/20 bandpass emission filter), branching patterns and blood flow direction. Imaging was performed on a Spectra PhysicsMaiTai HP DeepSee/Olympus Fluoview FV1000 multiphoton imaging setup with a 25× NA 1.05(19.6% increase in vessel diameter; *P* = 0.0069, *t*-test). Interestingly, smaller arterioles (1 to 25 μm diameter) in Tat-tg mice treated with the PDE5 inhibitor exhibited a robust dilatory response (20.6% increase in vessel diameter) to brief hypercapnia (Figure [5](#F5){ref-type="fig"}H), which was statistically equivalent (*P* = 0.5447; *t*-test) to the dilatory response of comparably sized vessels in WT animals (19.1% increase in vessel diameter). The dilation of larger arterioles (26 to 50 μm diameter) in Tat-tg mice was also enhanced by treatment with the PDE5 inhibitor (10.6% increase in vessel diameter), compared to untreated Tat-tg mice (6.7% increase in vessel diameter) (*P* = 0.0187; *t*-test). However, the dilatory response of these treated larger vessels was not fully restored when compared to WT mice (20.5%) (Figure 7I; *P* \<0.0001;


*t*-test).

Discussion
==========

We used hypercapnia as an experimental tool to examine the regulation of cerebrovascular reactivity in the context of HIV-induced neuroinflammation. Our initial experiments used a relatively extended (5 minute) exposure to moderate hypercapnia, consistent with previous studies in other mouse and rat models of cerebrovascular reactivity (6% CO~2~ stimulus with 9-minute evaluation of CBF) \[[@B45]-[@B47]\]. These studies demonstrated a significant loss of normal vascular responsiveness to hypercapnia in Tat-exposed mice, relative to controls (Figure [1](#F1){ref-type="fig"}). However, we noted that there was considerable acidemia in the animals at the end of this CO~2~ administration period (Table [1](#T1){ref-type="table"}). Respiratory acidosis of this kind \[[@B18]\] can stimulate systemic hemodynamic change through β-adrenergic signaling \[[@B16],[@B17]\]. To avoid this, we therefore explored the administration of a 30-second CO~2~ challenge. This shorter hypercapnic exposurefollowing brief hypercapnic stimulation. Additionally, it is possible that already available PDE5 inhibitors could be used to limit further neuroinflammation initiated by transient episodes of tissue ischemia, due to decreased CVR to CO~2~ or other CBF regulators signaling through the NO-cGMP pathway.

Overall, this study reports three major findings. First, HIV-associated neuroinflammation (induced by either acute or chronic exposure to HIV-1 Tat) produced a cerebrovascular pathology, that was uncovered upon brief exposure to moderate hypercapnia. Second, this cerebrovascular pathology may selectively affect larger vessels (\>25 μm) and finally, inhibition of PDE5 by gisadenafil besylate restored the normal cerebrovascular response to transient hypercapnia in mice with underlying HIV-associated neuroinflammation by fully restoring the dilatory capacity of the smaller pial arterioles. These findings may have important implications for persons living with


model, elicited by unilateral carotid artery ligation and exposure to 8% oxygen in 7 day old (P7) rats. Of particular importance for this proposal, we developed protocols for evaluation of interactions between moderate hypothermia and other therapies that incorporate neuropathological and functional outcome measures. In preliminary studies, DHA was administered parenterally, rather than orally, to neonatal (P7) rats; DHA had neuroprotective properties. This finding provided compelling proof of principle that systemic fatty acid composition influenced susceptibility to neonatal hypoxic-ischemic brain injury. Moreover, our most recent data demonstrate that a single injection of DHA increased the neuroprotective efficacy of subsequent brief moderate hypothermia. We are excited about the potential to translate these findings to clinical studies. Essential prerequisites include: (i) evaluate interactions between DHA supplementation and hypothermia in hypoxic-ischemicbest file format? Could I use .txt? I've seen .bin somewhere too. How do I choose?

A:

 FileOutputStream saveFile = new FileOutputStream("SaveObj.sav", true);

According to the documentation:

Creates a file output stream to write to the file represented by the specified File object. If the second argument is true, then bytes will be written to the end of the file rather than the beginning.

A:

You can append to the end of the file by passing true to the FileOutputStream constructor as in
http://docs.oracle.com/javase/6/docs/api/java/io/FileOutputStream.html#FileOutputStream(java.lang.String, boolean)
However, this poses an interesting question.  When reading the file, how do you know how many objects were saved?  To read in every object, you want to call readObject N times, once for each object, but you need to know what N is, otherwise you read past the


   public $total = 20;
    public function doDiscounts($logic = null) {
        $this->total = $logic ? $logic->applyDiscount($this->total) : $this->applyDiscount($this->total);
        echo $this->total;
    }
}

, body
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  , constructors
  , definition
  , definitions
  , derivedConstraints
  , expr
  , fields
  , function
  , functionDefinition
  , getAnn'
  , imports
  , instanceName
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  , moduleName
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  , pattern'
  , pragmaSpecification
  , signatures
  , typeDefinition
  , whereBindings
  , wrappedType
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import qualified Axel.Parse.AST as Parse
import qualified Axel.Sourcemap as SM
import Axel.Utils.List (unsafeHead)

import Control.Lens.Operators ((^.), (|>))

import qualified Data.Text as T

-- | Metadata is only approximately restored. Thus, `Axel.Normalize.normalizeExpression` and
-- | `denormalizeExpression` are only inverses if metadata information is
-- | ignored, although they should be pretty close either way.
denormalizeExpression :: SMExpression -> SM.Expression
denormalizeExpression (ECaseBlock caseBlock) =
  let ann' = getAnn' caseBlock


   , denormalizeExpression (letBlock ^. body)
        ]
denormalizeExpression (ELiteral x) =
  case x of
    LChar _ char -> Parse.LiteralChar (getAnn' x) char
    LFloat _ float -> Parse.LiteralFloat (getAnn' x) float
    LInt _ int -> Parse.LiteralInt (getAnn' x) int
    LString _ string -> Parse.LiteralString (getAnn' x) (T.unpack string)
denormalizeExpression (EPatternBinding patternBinding) =
  let ann' = getAnn' patternBinding
   in Parse.SExpression
        ann'
        [ Parse.Symbol ann' "@"
        , denormalizeExpression (patternBinding ^. name)
        , denormalizeExpression (patternBinding ^. pattern')
       ]
denormalizeExpression expr'@(ERawExpression _ rawSource) =
  let ann' = getAnn' expr'
   in Parse.SExpression
        ann'
        [Parse.Symbol ann' "raw", Parse.LiteralString ann' (T.unpack rawSource)]
denormalizeExpression (ERecordDefinition recordDefinition) =
  let ann' = getAnn' recordDefinition
      denormalizedBindings =
        map
          (\(var, val) ->
             Parse.SExpression
               ann'
               [Parse.Symbol ann' (T.unpack var), denormalizeExpression val])


(Parse.Symbol ann' (T.unpack $ fnDef ^. name) :
         map denormalizeExpression (fnDef ^. arguments)) :
      denormalizeExpression (fnDef ^. body) :
      map denormalizeStatement (fnDef ^. whereBindings)
denormalizeStatement (SMacroDefinition macroDef) =
  let ann' = getAnn' macroDef
   in Parse.SExpression ann' $ Parse.Symbol ann' "=macro" :
      Parse.Symbol ann' (T.unpack $ macroDef ^. functionDefinition . name) :
      denormalizeExpression
        (unsafeHead $ macroDef ^. functionDefinition . arguments) :
      denormalizeExpression (macroDef ^. functionDefinition . body) :
      map denormalizeStatement (macroDef ^. functionDefinition . whereBindings)
denormalizeStatement (SMacroImport macroImport) =
  let ann' =     ann'
           (Parse.Symbol ann' "list" :
            map denormalizeExpression (typeclassDefinition ^. constraints)) :
         denormalizeExpression (typeclassDefinition ^. name) :
         map
           (denormalizeStatement . STypeSignature)
           (typeclassDefinition ^. signatures))
denormalizeStatement (STypeclassInstance typeclassInstance) =
  let ann' = getAnn' typeclassInstance
   in Parse.SExpression
        ann'
        (Parse.Symbol ann' "instance" :
         Parse.SExpression


Laffont et al. would have a pivot height of more than 70 percent of the total water depth. As will be apparent from the following discussion of the present invention, for a structure such as the one illustrated in FIG. 5 of Laffont et al, a pivot height of 70 percent of the water depth would likely result in a structure having a considerably higher flexural vibration period than a compliant tower in the same water depth and having comparable stiffness and weight distribution.builds on available customer information to improve registrations rates; real-time alerts on hot leads triggered to sales reps via mobile devices; and anonymous lead tracking and profiling, to enable the targeting process to begin even before a user puts his hand up with a formal registration.


Imagine being able to put an air conditioner in your pocket or never worrying about your smartphone overheating again. Those dreams could one day be reality, thanks to a pocket-sized cooler developed by researchers at UCLA.

The tiny device, described in the journal Science, could potentially be used to build quieter, more energy-efficient and environmentally friendly cooling systems.

Current air conditioners are loud, heavy and not exactly green; they put a lot of carbon dioxide into the air and typically involve pumping refrigerant fluids that are not good for the environment if a unit is broken or improperly disposed of. Newer devices called thermoelectric coolers need costly ceramic materials, and they don’t appear to cool things as efficiently as those traditional vapor-compression devices.

But the new device takes advantage of electrocaloric        if (resourceValue != null) {
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              textValue = StringUtil.notNullize(textValue);

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              List<String> dirNames = Collections.singletonList(targetDir);
              if (destFolderResources.containsEntry(item.getName(), item.getType())) {
                AndroidResourceUtil.changeValueResource(project,


I’m very glad I’ve put you on the spot.” But Peterson pursued: “Well, you get my point. You’re doing what you should do, which is digging a bit to see what the hell is going on. And that is what you should do. But you’re exercising your freedom of speech to certainly risk offending me, and that’s fine. More power to you, as far as I’m concerned.”

Newman had no answer. Point to Peterson.

But despite Peterson’s obvious logic, the Left refuses to concede this particular point. Any statement — any statement — must be gauged not only on the basis of its truth-value, according to the Left, but on the basis of whether such truth is likely to offend — or, at least, whether such truth is likely toto cow them into silence.

The Left has wielded the Right’s preference for manners as a club against the Right, claiming offense in order to cow them into silence.

Of late, however, the Left has simply gone too far. No longer do they ask whether objectively offensive statements ought to be made; they now take each statement and ask whether it is subjectively offensive to anyone. First person to claim offense wins. Which is precisely why Peterson’s logic trips up Newman: He plays her own card against her. By demonstrating that anyone can be offended by anything, he returns the conversation from the vague recesses of subjective reaction to the hard and fast ground of objective truth.

This is the ground on which conservatives should fight, of course: acknowledgement that while


the leadership of Professor Mark Vygodsky he defended his thesis on the topic "From the history of the theory of functions of a complex variable". He was one of the first scientists in USSR to specialize in the field of history of mathematics (which was viewed ambiguously by the Soviet academic circles at that time), and specifically studied the history of the theory of analytic functions. He was the author of a number of scientific works and monographs: "The main stages in the development of the general theory of analytic functions" (1962), "Five famous problems of antiquity" (1975), etc.

He laid the foundations of a thorough study of the history of Saratov State University, and was the author of various publications on that topic. For many years he readEducation in freedom

Main menu

Post navigation

The origin of the university

The origin of the university in western culture, starting around the second millennium of the common era, is a community of scholars in a committed search for truth. That has been increasingly obscured in the third millennium of the common era with disciplinary monomania, abuse of power by “teachers” over “students” and corruption causing a crisis in replicability of results so profound that even the corporations parasitic on the taxpayers’ money used for their “research” at these “ universities” have begun to fund their own replication studies.

The rampant abuse of power reflects the greater society in which blanket warrantless surveillance is combined with the threat of torture and the militarization of police to create a society even less free than


cases above, the dilapidated railway line. AusAID is contributing an estimated $25 million towards the $138 million dollar project, managed by the Asian Development Bank and the Government of Cambodia to rehabilitate the railway lines of Cambodia.

Many households are now unsustainably indebted due to suffering the double indignity of losing their homes then having to borrow money from loansharks to build new ones. Two children drowned in 2010 at one of the resettlement sites while searching for clean water which was supposed to be supplied. The AHRC complaint also alleges that in 2011, another child was killed and another seriously injured while walking the four kilometres to get to the nearest school — the families were told prior to moving that the resettlement site was to have aamplitudes and gamma band power, respectively. Hypnotic suggestions exerted a top-down modulatory effect on both evoked and induced-cortical brain responses triggered by selective nociceptive laser inputs. Furthermore, correlation analyses indicated that gamma power modulation and suggestions of hyperalgesia may reflect the process of allocating control resources to salient and threatening sensory-affective dimensions of pain.


a total-confinement hog

feedlot in Todd County. The feedlot is expected to house approximately 2,930 sows, 300

nursery pigs, and 750 gilts.

       In 2012, the Gourley facility underwent environmental review. See Minn. Stat.

Ch. 116D; Minn. R. 4410.1000. The Minnesota Pollution Control Agency (MPCA),

acting as the responsible government unit (RGU), prepared an environmental assessment

worksheet (EAW).       MPCA completed and distributed the EAW in July 2012.             It

concluded that the facility “does not have the potential for significant environmental

effects,” and issued a negative declaration on the need for an environmental impact

statement (EIS). Relators did not appeal the negative declaration on the need for an EIS.

     from Gourley,

including property tax information, and a detailed breakdown of estimated daily and

annual water usage, which Gourley subsequently provided.

      On October 4, 2013, MDNR issued Gourley a water-appropriation permit. The

permit enables the facility to appropriate up to 8,000,000 gallons of water annually. On

November 1, relators submitted a written demand for a hearing on the issuance of the

permit under Minn. Stat. § 103G.311 (2012). On November 5, MDNR denied this

request, concluding that relators are not one of the parties permitted to demand a hearing

under Minn. Stat. § 103G.311, subd. 5(a). This certiorari appeal follows.


  where . . . substantial commitments have been made.

See City of Minneapolis v. Wurtele, 291 N.W.2d 386, 391 (Minn. 1980); Manco of

Fairmont, Inc. v. Town Bd. of Rock Dell Twp., 583 N.W.2d 293, 295 (Minn. App. 1998),

review denied (Minn. Oct. 20, 1998). We disagree. To determine whether the doctrine of

substantial compliance applies to a specific ordinance or rule, we determine first whether

the ordinance or rule in question is mandatory or directory. See Manco, 583 N.W.2d at

295. To determine whether a statute is mandatory rather than directory, we consider

whether the statute expresses the consequences of a failure to comply with its provisions;

if it does, it is mandatory. Sullivan v. Credit River Twp., 299 Minn. 170, 176-77, 217

N.W.2d 502, 507 (1974). Because there is no consequence listed forIn cellular communication, a user equipment (UE) existing in a cell accesses a base station to receive control information for exchanging data from the base station in order to perform communication and then transmit and receive data to and from the base station. That is, since the UE transmits and receives data via the base station, the UE transmits data to the base station in order to transmit the data to another cellular UE and the base station, which has received the data, transmit the received data to another UE. Since the UE must transmit data to another UE via the base station, the base station schedules channels and resources for data transmission and reception and transmits channels and resource scheduling information to each UE. In order to


perform UE-to-UE communication via a base station, the base station needs to assign channels and resources for transmitting and receiving data to each UE. However, in D2D communication, a UE directly transmits and receives a signal to a desired UE without via a base station or a relay.
If UE-to-UE communication or D2D communication for directly transmitting and receiving data between UEs is performed by sharing resources with an existing cellular network, each UE may perform UE-to-UE communication after resource assignment for UE-to-UE communication. However, in communication between UEs using different frequencies, it is necessary to determine operating frequencies upon resource assignment. That is, one of first and second UEs, which subscribe to different communication operators, may move to an operating frequency of a peer UE for D2D communicationsystem become integrable when both signal and control fields have equal atom-field coupling parameters and are in two-photon resonance, as has been shown by Park and Shin [@park1998matched] and Clader and Eberly [@clader2007two]. This leads to solitonic solutions even in non-ideal media preparation such as “mixonium” [@clader2008two], a partially coherent medium. Other studies have been carried out for the case of ultra-cold atoms, where one can neglect the effects of Doppler broadening and homogeneous relaxation. Given these assumptions, Groves *et al.* deduced a second order solution that led to an alternative scheme for storage and manipulation of light [@groves2013jaynes]. Complementary numerical simulations [@gutierrez2015manipulation] showed the relevance of this procedure even under the effects of the ever-present spontaneous emission. Here we continue this work by presenting new solutions that


is also worth noting that while the two pulses are active, the area of the individual pulses is no longer equal to $2\pi$ but the total pulse area as defined in [@clader2007two], $$\theta_\text{tot}=\sqrt{|\theta_{13}|^2+|\theta_{23}|^2},
\label{atot}$$ remains constant and equal to $2\pi$. After the storage process is over, $t/\tau_a\gg1$, we have a $2\pi$-control pulse propagating away at the speed of light as it is decoupled from the medium. Both signal and control pulses have a duration of $\tau_a$ and are time-matched.

Another possibility is taking one of the integration constants to be zero. If $a_1=0$ then we obtain a type 2 solution which is a $2\pi$-control pulse traveling at the speed of light completely decoupled from the medium. If instead we take $a_2=0$ we end up with an SIT solution for the$\Lambda$-system: Each imprint made by the storage of two signal pulses of duration $\tau_a$ and $\tau_b$. The vertical continuous lines show the location of each imprint and the dashed ones show where they would have been encoded if they had been by themselves.](density2)

There are several things to comment about these expressions but the most obvious and somewhat shocking is that the parameters $\eta_{13}^a$ and $\eta_{13}^b$ are nowhere to be found. This means that the temporal order in which the imprints were made is irrelevant; the only thing that matters is the spatial ordering as it is shown by the dependence on $\eta_{12}^a$ and $\eta_{12}^b$. Therefore the two processes depicted in Fig. \[pulse2\] lead to the same result. On one hand, we have the situation assumed here, namely, that the


on the other hand, we have the situation where the signal pulse $\tau_b$ encodes its information into the medium first. Then comes the second signal pulse $\tau_a$. When it comes close to the imprint it acts as a backward-transfer solution, thus displacing the imprint by the amount discussed in Sec. \[backtransf\]. Then, it continues its propagation but, due to the translation it suffered while displacing the first imprint, it encodes its information into a displaced location. This complicated pulse dynamic is displayed in Fig. \[pulse2\](b).

Regardless of which situation took place, the location of the two imprints is now given by,

$$\begin{aligned}
\kappa_a x_2^a & =\eta_{12}^a+\sigma\delta^{ab},\\
\kappa_b x_2^b & =\eta_{12}^b-\sigma\delta^{ab}.\end{aligned}$$

An example of the resulting imprints after the two pulses have stored their information is presented in Fig. \[den2\]. The vertical dashed lines show the predictedthus effectively inverting the order of the imprints.

If instead of moving the imprints with a control pulse we had chosen a type 3 first order solution then everything would have been reversed. The imprints would be moved to the left according to the results derived in Sec. \[backtransf\]. Here again, there is an option for inverting the order of the imprints. If the duration of the type 3 pulse is tailored so that the imprint on the right is displaced more that the separation between imprints plus their widths, then the order is reversed. Each imprint would be moved in a different direction as well: The imprint on the right is displaced to the left by the signal pulse and the imprint on the left is pushed to the


on Thanksgiving and at Christmas, and her fancy silver. We would share the responsibilities; she would always do the turkey, my sister would make the cranberry apple, and I would help with the side dishes and dessert.
This year my whole family drove up to Maryland to have Thanksgiving together. My mom loved that I loved to cook; she would play with the kids and keep them busy while I fixed dinner. It was a great arrangement that I appreciated, too, because it gave me some down time to myself, and she had a chance to play with the kids. Because her kitchen was organized differently from mine, several times during a meal preparation I would walk into the living room and ask her, “Hey, Mom, where do youa mother means to you, especially when you’re not the type to write poetry or tell flowery stories. She was very transparent; what you saw was what you got; there were no games, no manipulation, no appeals to emotion or guilt trips. Always avoiding confrontation, she was so easy to love and always the life of the party. Six months later, the grief that covers me comes after the simple things. Finding a great deal on a pair of shoes; using a good coupon at Macy’s; trying a new recipe that was a flop; making a huge batch of peppermint bark popcorn. I cannot articulate my love for her, but many friends have said again and again that they know how much I loved her, because of the


No. 3
Katie Pertiet On the Go Alpha
Lynn Grieveson DIY Ripped and Stitched No. 2
Katie Pertiet Date Tags No. 3
Katie Pertiet Email Inspiration
Katie Pertiet Leaf Charms
Katie Pertiet Lil Bits Staple
Katie Pertiet Atlantic Kit
Katie Pertiet Curled Note Paper

24 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=190984&title=photo-swap-for-carolynn-mamabean&cat=2389
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=190984&title=photo-swap-for-carolynn-mamabean&cat=2389Wed, 20 Mar 2013 01:21:19 +0000December 2

by: dugarner

Description}: Today's photos.
Katie Pertiet Krafty Christmas
Katie Pertiet Drop Shadows
Katie Pertiet Counting Christmas Tags
Katie Pertiet Cardstock Tabs No. 2
Katie Pertiet Crystallized Edgers
Katie Pertiet Holiday Monograms
Katie Pertiet Flourished Christmas
Katie Pertiet Inked Flakes No. 1
Ali Edwards December Daily Layered Templates No. 3
Katie Pertiet Holiday Giveaway 2010
Katie Pertiet Wooden Alpha No. 6
Katie Pertiet Defined Discs Holiday No. 2
TFL!

10 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=185317&title=december-2&cat=1713
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=185317&title=december-2&cat=1713Mon, 03 Dec 2012 00:33:42 +0000December 1

by:7 and 8

by: dugarner

Description}: [IMG]http://i1139.photobucket.com/albums/n545/sarah_m_garner/BlackBayouPage7and8Photobucket.jpg[/IMG]
This is my second Black Bayou Lake book. These pictures were taken between May 2010 and January 2012. Most of these photos have shown up on other layouts, this is just a collection of pictures taken at this one particular wildlife reserve.
Supplies:
Katie Pertiet Pocket Pages Layered Templates 1 and 2
Katie Pertiet Classic Cardstock Carnival
Katie Pertiet Krafty Woods
Katie Pertiet Gator Crossing Kit
Katie Pertiet Littlest Farmer
Katie Pertiet Pelican Park
Katie Pertiet Chat Freebie
Katie Pertiet Curled Journal Spots No. 2
Katie Pertiet New Growth No. 6
TFL!

10 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171863&title=black-bayou-pages-7-and-8&cat=500
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171863&title=black-bayou-pages-7-and-8&cat=500Sat, 18 Feb 2012 16:24:56 +0000Black Bayou Pages 17 and 18

by: dugarner

Description}: [IMG]http://i1139.photobucket.com/albums/n545/sarah_m_garner/BlackBayouPage17and18Photobucket.jpg[/IMG]
This is my second Black Bayou Lake


so I'm using it for the cover and title page of this book.
Supplies:
Katie Pertiet Scrap Pack No. 2
Katie Pertiet Naturally Krafty No. 7
Katie Pertiet Naturally Krafty No. 8
TFL!

15 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171584&title=black-bayou-lake-cover-and-title-page&cat=500
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171584&title=black-bayou-lake-cover-and-title-page&cat=500Sun, 12 Feb 2012 23:07:04 +0000Black Bayou Lake Pages 3 and 4

by: dugarner

Description}: Starting a second Black Bayou Lake book. These pictures were taken between May 2010 and January 2012. Most of these photos have shown up on other layouts, this is just a collection of pictures taken at this one particular wildlife reserve.
Supplies:
Katie Pertiet Classic Cardstock Oyster
Katie Pertiet Classic Cardstock Hereford
Katie Pertiet Pocket Pages Layered Templates 1 and 2
Katie Pertiet Cut Ups Fall
TFL!

12 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171581&title=black-bayou-lake-pages-3-and-4&cat=500
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171581&title=black-bayou-lake-pages-3-and-4&cat=500Sun, 12 Feb 2012 22:48:02 +0000Black Bayou Lake

by: dugarner

Description}: Starting a second Black Bayou Lake book. These pictures were taken between May 2010 and January 2012. Most of these photos have shown up on other layouts, this is just a collection of pictures taken at this one particular wildlife reserve.
Supplies:
Katie Pertiet Classic Cardstock Oyster
Katie Pertiet Classic Cardstock Hereford
Katie Pertiet Pocket Pages Layered Templates 1 and 2
Katie Pertiet Cut Ups Fall
TFL!

11 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171578&title=black-bayou-lake&cat=500
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=171578&title=black-bayou-lake&cat=500Sun, 12 Feb 2012 22:45:09 +0000Jake and the Pirate Ship

by: dugarner

Description}: Scored some great booty (pun intended!) at the sale this week, finally picked up Mindy's Little Treasures collection. I've been eyeballing it since Jake was born but now I'm convinced he's old enough that


class="imgborder" title="Monroe_Symphony_Right.jpg" border="0" src="http://www.designerdigitals.com/digital-scrapbooking/ideas/data/500/thumbs/Monroe_Symphony_Right.jpg" alt="Monroe_Symphony_Right.jpg" />

by: dugarner

Description}: I play in a small, local, community orchestra. Our woodwinds and brass all have performance degrees (MMus or PhD) but our strings are largely hobby players. Many have degrees as well, while others are just happy to have an ensemble to play in. We are one of the few semi-professional orchestras in the country (we are pay-per-service, not salaried/union) that has operated in the black continuously since founding.
I play the viola and sit either principal or second chair, depending on whether or not our principal viola decides to show up for a concert. I love playing with this group, and this is my tenth season.
This concert, a friend of mine used my camera and took pictures duringa young child to enjoy. Even if I could eat rice, I wouldn’t like sushi because the nori is too bitter for me. Bailey likes sour and bitter things, so it’s right up her alley. She eats all the vegetable varieties, but her favorite is the salmon, cream cheese, and avocado. She also likes the crab, carrot, and cucumber variety. I don’t know what other kinds she’s tried, but she’s liked everything as long as it’s not too hot. I make sushimaki at home sometimes (with the rice on the outside), rolled in toasted sesame seeds. Bailey and Duane eat it as quickly as I can roll it.
Duane saw this scarf on the web a few weeks back and asked me about it. I couldn’t find one to


Season Stickers
Katie Pertiet Capped Holiday
Katie Pertiet Groceria Words Holiday
TFL!

13 commentshttp://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=167503&title=december-daily-december-4-right&cat=1713
http://www.designerdigitals.com/digital-scrapbooking/ideas/showphoto.php?photo=167503&title=december-daily-december-4-right&cat=1713Tue, 06 Dec 2011 02:01:51 +0000December Daily December 4 Left

by: dugarner

Description}: I am really struggling. We've had cold, rainy weather here for the past two days and outside pictures are not options. Nothing happened yesterday or today . . . so I cheated. It's hard to fill two pages when you only have one photo! These are the yarns my friend Emily is going to use to make a sushi roll scarf for Bailey. (See facing page)
Supplies:
Katie Pertiet Days of December Templates No. 4
Katie Pertiet Tis the Season Papers
Katie Pertiet Yarn Swirls No. 11
Katie Pertiet Tis the Season Stickers
Katie Pertiet Capped Holiday
Katie Pertiet Groceria Words Holiday
TFL!<brthe blade and disc dovetail to maintain low friction and prevent damage to the metal surfaces.
During service operation, the rotor blade assembly is subject to a complex loading system, comprising centripetal load, gas load and vibration. Rotation of the fan assembly results in a large load on the dovetail root, due to centripetal acceleration, as the blade tries to pull out of the retention slot. Hoop stresses are generated in the disc rim, as the disc grows under the influence of its own mass and those of the attached blades. In addition, as the fan blade compresses the incoming air, the pressure differential across the blade causes the aerofoil to bend, imparting an additional bending load into the dovetail root. Finally, blade mechanical resonances, and aerodynamic forcing, impose


All relevant data are within the paper and its Supporting Information files. The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD004114.

1. Introduction {#sec001}
===============

The importance of seafood in human nutrition and the ability of aquaculture, as it meets the increasing demand for seafood, to provide nutrients traditionally supplied by seafood, particularly key fatty acids, are central issues in global food security \[[@pone.0161513.ref001]\]. The absolute content of omega-3 longchain (≥C~20~) polyunsaturated fatty aci**d** (n-3 LC-PUFA), particularly docosahexaenoic acid (22:6n-3, DHA) and eicosapentaenoic acid (20:5n-3, EPA), is one of the critical contributions that Atlantic salmon makes to human diet and nutrition \[[@pone.0161513.ref002]\], and the benefits of an adequate dietary supply of n-3 LC-PUFA are well documented \[[@pone.0161513.ref003], [@pone.0161513.ref004]\].attempt to perform a preliminary validation of an oil with high DHA and ALA profile in salmon, thereby aiming to assist in the further development and use in aquafeeds of novel DHA-containing oils with high ALA content.

A more precise control of feed composition requires both a broader screening and a more sensitive approach to understanding dietary induced physiological changes in fish. This can be achieved by being able to interpret changes in the liver proteome, as previously reported in response to other dietary modifications \[[@pone.0161513.ref023], [@pone.0161513.ref024]\]. The liver is a crucial site for fatty acid metabolism and body lipid homeostasis in Atlantic salmon and possesses other regulatory functions related to protein and carbohydrate metabolism, immunity or xenobiotic metabolism \[[@pone.0161513.ref022], [@pone.0161513.ref025]\]. With regard to the specific use of sustainable


    6
  Stay-C[^7^](#t001fn008){ref-type="table-fn"}                    1.5     1.5     1.5
  Choline chloride[^8^](#t001fn009){ref-type="table-fn"}          1       1       1
  Alpha-celullose[^8^](#t001fn009){ref-type="table-fn"}           7.5     7.5     7.5
  Yttrium oxide[^8^](#t001fn009){ref-type="table-fn"}             1       1       1
  Sipernat[^10^](#t001fn011){ref-type="table-fn"}         0.09% for dry matter, 89.3 ± 0.32% for crude protein, 94.0 ± 0.08% for lipid, and 80.6 ± 0.93% for gross energy.

AD for fatty acids was significantly affected by dietary oil source, however, differences were smaller than 3% for most individual and classes of fatty acids ([S1 Table](#pone.0161513.s004){ref-type="supplementary-material"}). AD of DHA was lowest (p~diet~ = 0.004, F~diet~ = 9.993) in TOFX fish, whereas AD of EPA and other n-3 LC-PUFA were not different across treatments. AD of ALA was lowest (p~diet~ = 0.000, F~diet~ = 30.110) in TOFX fish, and the same pattern was also followed for total n-3 PUFA (p~diet~ = 0.002, F~diet~ = 12.780) and total PUFA (p~diet~ = 0.035, F~diet~ = 5.275). AD of total MUFA was higher (p~diet~ = 0.042, F~diet~ = 4.819) in


This reached absolute contents of 2160 mg per 100 g (dry weight) in TOFX fish, and despite not being as high as in FO fish (2760 mg per 100 g), provided an extra 450 mg per 100 g muscle relative to the current industry FOPO diet.

Although the importance of ALA from a health perspective has been generally less reported relative to n-3 LC-PUFA, ALA is receiving interest as a nutraceutical supplement, based on reports of beneficial effects similar to those of n-3 LC-PUFA \[[@pone.0161513.ref044]\]. ALA is a minor fatty acid in marine oils, however, it is highly and naturally present in *Camelina* and other transgenic oilseeds such as canola, reaching proportions of over 25% of the total fatty acids in oils extracted from transgenic seed \[[@pone.0161513.ref018]\]. Given thediet. From the human consumer perspective, DHA-containing oils extracted from transgenic terrestrial oil seeds are therefore potentially suitable as a means to improve the nutritional quality for consumers of salmon fillet. The particular fatty acid profile of the TOFX oil also promoted a more efficient deposition of n-3 LC-PUFA in muscle and liver in relation to a fish oil-based diet; this was attributed to less inefficient utilization, in particular as occurs via beta-oxidation, of n-3 LC-PUFA due to the higher DHA:EPA ratio, rather than to bioconversion from the high**er** content of the ALA precursor. The TOFX oil triggered an oxidative stress response that was likely associated to impaired growth. This draws attention to the necessity of considering the balance between total and specific PUFA and antioxidant levels present


Blubos

Blubos is a genus of beetles in the family Laemophloeidae. The only known species in the genus is Blubos matris, a large (4 mm) yellowish beetle with darkly fasciate elytra. It differs from all other known laemophloeids in that the lateral margins of the pronotum are visible in dorsal view. It is known from a single specimen collected more than 60 years ago in the Democratic Republic of the Congo. Nothing is known of its biology or immature stages.

References

Category:Laemophloeidae
Category:Cucujoidea generainvention is provided on the dielectric member on which a planar circuit is formed, there is no need to employ a structure in which the planar circuit formed on the dielectric member and the nonreciprocal circuit device formed on the magnetic member are connected.
According to another aspect of the present invention, there is provided a nonreciprocal circuit device including conductive films formed on both sides of a dielectric member defining first and second slots which oppose each other, a magnetic member having ferrimagnetic characteristics being stacked on the dielectric member, and a resistive film, which opposes one of the areas of the first and second slots, formed on the magnetic member. A DC magnetic field is applied to the dielectric member and the magnetic member so as to


the HPSEC-MALS analysis (Normandie Univ, UNIROUEN, INSA Rouen, CNRS, PBS, 76000 Rouen, France), Jacques Desbrières (Université de Pau et des Pays de l'Adour (UPPA), IPREM, UMR 5254 CNRS/UPPA, Helioparc Pau Pyrénées, 2 avenue P. Angot, 64053 PAU CEDEX 09, France) for the ^1^H-NMR and Diana Constantinescu-Aruxandei, for helpful discussion and English editing.

Conceptualization, B.T., C.D., A.-V.U., P.M., and G.D.; Investigation, B.T., F.G., P.M. and F.O.; Methodology, B.T., F.G., A.-V.U. and G.D.; Supervision, C.D., T.D. and G.D.; Writing---original draft, B.T., C.D. and G.D.; Writing---review & editing, B.T., C.D., T.D. and F.O.

This research was founded by a grant from the Hubert Curien (PHC) Brancusi 2017 Programme, project number 38365QK entitled \"*On the advanced processing of marine algae from Romanian Black Sea edge*\" and by the project PN19.23.01.01 "*Integrated platform for smartClassen, et al. Ann. Phys. [**506**]{}, 315 (1994).

Amorphous Solids. Low Temperature Properties (Edited by W.A. Phillips), Springer, Berlin (1981).

See review A. L. Burin, D. Natelson, D. D. Osheroff, Yu. Kagan, Chapter 5 in *Tunneling Systems in Amorphous and Crystalline Solids*, ed. by P. Esquinazi, p. 243 (Springer, 1998) and other reviews in this book.

D. J. Salvino, S. Rogge, B. Tigner, D. D. Osheroff, Phys. Rev. Lett. [**73**]{}, 268 (1994).

A. L. Burin, J. Low Temp. Phys. **100**, 309 (1995).

H. M. Carruzzo, E. R. Grannan, C. C. Yu, Phys. Rev. B [**50**]{}, 6685 (1994). M.S. Khalil et al., experimental paper to be published

M. v. Schickfus and S. Hunklinger, Phys. Lett. A [**64**]{}, 144 (1977).

J. Dalibard, Y. Castin, K. Molmer, Phys. Rev. Lett. [**68**]{}, 580 (1992); P. Gross, D. Neuhauser, H.


reported near-perfect agreement among members of the SOSG; however (as coauthors of the SINS), once again this sample would have increased familiarity with the SINS.^[@bibr48-2192568217750125]^

Campos et al performed a similar study using a smaller sample size totaling 6 clinicians (3 spinal surgeons, a general orthopedist, a radiotherapist, and a palliative care physician), reporting excellent agreement, while Fisher et al compared the reliability of the SINS between 37 radiologists and also reported excellent agreement.^[@bibr49-2192568217750125],[@bibr50-2192568217750125]^ Somewhat contrary to the findings of Arana et al, Teixeira et al found decreased agreement for clinicians with limited experience with spinal metastatic disease.^[@bibr51-2192568217750125]^ One should note, however, a key difference between the studies performed by Arana et al and Teixeira et al is the composition of their reviewers; for Arana et al the reviewers       0
  Total points
   Group A^a^           0-3
   Group B              4-5
   Group C              6

Abbreviations: KPS, Karnofsky Performance Score.

^a^Group A median survival = 3.0 months. Group B median survival = 9.0 months. Group C median survival = 18.7 months.

Similarly to the OSRI, the Van der Linden score included the performance status and the primary tumor type, with the addition of the presence or absence of visceral metastases. The Van der Linden score was further


The Rades score is outlined in [Table 8](#table8-2192568217750125){ref-type="table"}. Using this scoring system, Rades et al successfully differentiated which patients benefitted from longer courses of radiotherapy. The Rades score considers the type of primary tumor, the presence of bone and/or visceral metastases, the time lag between diagnosis and development of MSCC, the ambulatory status before radiotherapy, and the duration of motor deficits before radiotherapy. The Rades score was validated on a sample of 439 patients in 2010.^[@bibr57-2192568217750125]^ The Rades score is designed only for patients with advanced vertebral metastases and ongoing MSCC. Its purpose is to identify those patients most suited to a short rather than long course of radiotherapy. This is perhaps why it has better predictive power in patients with short survival and poorer predictive power inrendering some of the scoring systems less useful.

Another challenge with the use of scoring systems, even those developed within the last decade, is that the evolution of oncologic treatment and ever-improving ability to investigate disease burden has rapidly outdated them. What disease characteristics correlated well or poorly in the past may not necessarily do so in the present day if radiotherapy, chemotherapy, or surgical regimens have improved. The development of tyrosine kinase has significantly improved survival time for both metastatic renal cell carcinoma as well as lung cancer and is but one example of the dramatic affect new forms of treatments can have on patients' outlook.^[@bibr70-2192568217750125],[@bibr71-2192568217750125]^ On the surgical side, percutaneous techniques for spinal stabilization have meant, in theory at least, that patients can undergo a surgical procedure


circumstances of the statute. Even the broadest reading of the Food Security Act and the basic statutes creating the C.C.C. will not support the conclusion that preemption may be presumed or inferred: neither the pervasiveness of the federal scheme, the need for protecting an overriding federal interest, nor the existence of conflict between the benefit program and state secured transaction laws exist. The farm programs are primarily a matter between the federal government and the individual farmer. The government merely has a secondary interest in the use that the farmer makes of the proceeds.
Were Congress so inclined, it could clearly manifest an intent to control the use of the proceeds from the benefit program. Indeed, in other situations it has expressly *141 stated its intention of controlling the2000-2012 in Scopus database. Further analysis has been made to test whether IHD research publications were associated with the global burden of disease, income and development of countries.

Materials and Methods {#s2}
=====================

This is a scientometric study. In January 2015, Scopus database was searched for research publications indexed under the medical subject heading (MeSH) 'myocardial ischemia' including the following terms: coronary artery disease, coronary heart disease, and Ischemic heart disease. The number of research publications in Scopus database was recorded for each individual year 2000-2012, and for each country the aﬃliation of the authors was used for identifying affiliation of a research publication to a country. In this regard, the scientific output of 172 countries extracted from the Scopus database. The ﬁrst year for the search was 2000, because of


Q:

preg_match_all() [function.preg-match-all]: Unknown modifier ']'

Using a few different patterns but they each come up with this error - so what's wrong?
My shortest one to diagnose is:
$pattern = "<img([^>]*[^/])>";
preg_match_all($pattern, $subject, $matches);

Thanks

A:

You are lacking the regexp delimiters. Try:
$pattern = "#<img([^>]*[^/])>#i";

A:

A single slash is the default delimiter, which is why the character after it in your original regex was in the error-message.
Using the traditional slashes as delimiters and escaping the slash that is not a delimiter would look like this:
$pattern = "/<img([^>]*[^\\/])>/";

 # backward pass
        loss.backward()

        # this helps prevent exploding gradient in RNNs
        torch.nn.utils.clip_grad_norm_(model.parameters(), 0.1)

        # update parameters
        optimiser.step()

    # test examples
    for i in range(num_test_batches):
        with torch.no_grad():
            data, targets = get_batch(X_test, y_test, i, batch_size=batch_size)
            ytest_pred, _ = model(data, memory)

            test_loss = loss_fn(ytest_pred, targets)


organization seem (probably) unprofessional or untrustworthy.

So after what precedent succeed you discover the glad medium?

Qualitative probe (speaking into your clients, working suggestions surveys, interviewing prospects, and many others.) might help you uncover what folks care about when deciding into succeed enterprise along with your firm. What we’re about into say shouldn’t shock you — it’s frequent sense.

Your touchdown pages as well as homepage be going to talk precisely what customers need into prize, within the greater distilled type potential.

Reply the query of what your clients care greater about, as well as distill your reply within the greater easy as well as easy potential types. Clients who need numerous in-depth particulars will learn by your organization’s information middle, FAQs, case research, as well as different in-depth selling supplies. What’sof Historic Places listings in Waltham, Massachusetts

References

Category:Houses in Waltham, Massachusetts
Category:Houses on the National Register of Historic Places in Waltham, Massachusetts
Category:Queen Anne architecture in Massachusetts
Category:Houses completed in 1881
Category:1881 establishments in Massachusetts


forms - we have elected to treat the aluminum finish in a manner appropriate to the Machine Age era. All aluminum surfaces have undergone several polishing stages to maintain a mirror-like finish, and then been anodized for durability and high gloss. This anodization process can reveal subtle surface irregularities in the aluminum form which would be absent in a more muted finish, but we think the payoff in overall character is worth it. WE DO NOT REGARD THESE AS DEFECTS, SO IF THIS FREAKS YOU OUT THEN THIS MAY NOT BE THE PRODUCT FOR YOU.72-34, the defendant appeals from an order revoking probation.
The issues will be treated separately.

Case No. 74-84
On September 21, 1971, the defendant was convicted of aggravated battery and received a sentence of 3 to 10 years. On appeal the conviction was reversed and the case remanded for a new trial. The appellate court's mandate was filed in the circuit court on June 5, 1973.
Defendant was incarcerated in the Rock Island county jail from June 5, 1973, to July 6, 1973. On the latter date, he was observed to be in need of aid. On that same date, he was involuntarily transferred to the East Moline State Hospital. A petition was filed asserting that defendant was in need of hospitalization and mental treatment. A hearing was held on July 13,


design. “For content we look in Berwick literally for anything interesting, but for layout and stuff I look at magazines like ‘Vice’, that’s a really big influence for us, and I look at graphic design magazines for ideas because they’re always laid out really well.”

With the hotly anticipated launch of ‘The Trip’ fast approaching, Kyle says there’s lots to do. “At the moment I’m kind of regretting saying that the first issue is going to be out on July 1!” he admits, “but we’ll get there and I hope it goes down well. It’s quite fresh, I can’t think of anything like it round here before.”

When embarking on the project, Kyle knew it wouldn’t be easy. But he says he’s had help from unexpected places. “It’s a lotQ:

Tomcat project folder what to do?

This question might sound stupid, but I am in trouble.
A developer gave me a ready made application as is. I downloaded the zip file and found that it was not ready to use.
So in the root folder I have te following:

.settings Folder
src Folder
target Folder
pom.xml File
.classpath File
.gitignore File
.project File
log.roo File
.springBeans File

I tried to deploy this folder in Tomcat Manager but nothing happend. Can you give an advice what to do, to get this working?

A:

This is a maven project that was based on a roo project.
Maven:  http://maven.apache.org/guides/getting-started/maven-in-five-minutes.html
Roo: http://projects.spring.io/spring-roo/
To be able to run this in Tomcat you must first create a war file.
Try this in the folder in which you did this ls:
mvn package
(more details on generating a war file through Maven: http://maven.apache.org/plugins/maven-war-plugin/)
If it doesn't


work then it is because you don't have Maven installed. You also need Java installed.
If you don't know how to get Maven and Java going, then go back to the developer and ask for a "war" file that you can install on Tomcat.
If you have Maven and Java installed, you can simply type "mvn jetty:run" in the command line and that should start a web server on port 8080, with your application name. Something like
http://localhost:8080/<yourApplicationName>

lipids on Ras proteins," Gorfe said, "and lipidation is important for membrane binding of the protein. The thought was, if we inhibit one of the enzymes that actually puts lipids on Ras, we might dislodge it from the membrane surface, or we might be able to prevent it from membrane binding, and in so doing prevent its function."

These compounds failed because Ras is tricky. "If you knock out one of the enzymes that it uses, it just finds another to bind itself to the membrane," he explained.

For this and other reasons, Ras was considered undruggable, according to Gorfe. Interest in Ras as an anticancer drug target faded. Hope in targeting Ras has sprung up in the last five years due in large part to simulations and analyses enabled


Criminal Code Reform: Bills C-610 & C-592

June 13, 2014

In the past few months, two private member’s bills have been introduced to the House of Commons in an effort to amend Canada’s animal cruelty laws in the Criminal Code of Canada. In April 2014, MP Isabelle Morin introduced bill C-592 and in June, 2014 MP Irwin Cotler introduced bill C-610. Both of these private member’s bills seek to amend Canada’s federal animal cruelty provisions, governed by sections 444 to 447 of the Criminal Code.[1]

Canada’s Criminal Code animal cruelty provisions were first enacted in 1869 and reflected the customs, values and knowledge of that time. [2] They have remained largely unchanged, however, and thus animals are still considered property under the Criminal Code’s governance of property rights and offences connectedwho negligently causes unnecessary pain, suffering or injury to an animal or bird;

· Define “negligently” as a marked departure from the standard of care used by a reasonable person;

· Establish an offence for animal owners for wilfully or recklessly abandoning an animal or failing to provide suitable food, water, air shelter and care.

The progress of each bill can be followed at: http://www.parl.gc.ca and the Bills can be searched for by number.

Canada’s Criminal Code also has provisions which seek to prevent the unnecessary suffering of animals. A plain reading of the Criminal Code would lead one to think that Canada has a zero tolerance for animal cruelty.

Unfortunately, egregious acts of animal suffering have gone unpunished because the Criminal Code requires that ‘willful neglect’ be proven. This means that the


So, let’s get going on the so far known facts and other things about the movie.

Tom Holland as the Spider-Man, in Captain America: Civil War, earlier this year.

Theweb action has been watched many times earlier, in the preceding films, which Sony Pictures released under its own banner. But now, it’s in the hands of Marvel, to unleash a more impactful ‘homecoming’ of the new face of Spider-Man-Tom Holland. The already popular English actor and dancer is best known for playing the title role in Billy Elliot the Musical, at the Victoria Palace Theatre, London.In 2011, he was also cast in the British version of the animated film Arriety, which was produced by Japan’s Studio Ghibi. He also starred in the 2012 Academy Award nominated, The Impossible, directed bythe ‘Homecoming’. To intensify the anticipation for the ‘Homecoming’, Robert Downey Jr. has also been cast as the evergreen Iron Man, who will also play a crucial part in the film and assist the spidey! How cool it would be to witness the two intelligently funny characters together on the big screen-Iron Man with Spider-Man!

Hence, it can be said that,the yet to arrive Marvel production will be no less than a blockbuster, if made accordingly, as we expect it to be. In the case of Marvel, you can always rely on the expectations. And if it crosses the extreme levels, bingo! The Avengers Infinity War is not far from vision-miles away, so anything that comes before its release, will be properly inspected by the true Marvel fans, obviously.


"require any private career school offering unapproved programs to refund all tuition and fees paid by students who enrolled in such programs. . . ." Md.Educ.Code Ann. § 11-107(b). Further, full tuition refunds are required by the Commission whenever a private career school closes or otherwise discontinues a program. Id. at § 11-205(b)(2); COMAR 13B.01.01.05(I)(2) (1990).
The Commission has the power to enforce these requirements on its own initiative. It may cite schools for deficiencies concerning the Commission's "conditions and standards". Md.Educ.Code Ann. § 11-204. More importantly, it is authorized "to seek an injunction or other judicial remedy for any violation of this title or of the rules and regulations adopted under this title". Id. at § 11-107(a). (Emphasis supplied). The Commission's right to demand refunds is thus sufficientlyJames R. Corbitt Co., 48 B.R. 937 (Bankr.E.D.Va.1985); In re Carolina Sales, supra. As stated in In re James Corbitt, the legislative history mentions "service contracts, contracts for lessons, and contracts for gym memberships along with transactions with `retail merchants' as representative examples of situations in which the priority would apply." In re James R. Corbitt Co., 48 B.R. at 939. (Emphasis supplied.) Further, the language of the statutory priority is not limited to merchants. Therefore, there is no legal basis for the assertion by NTS that its students should not be granted the priority because NTS is not a retail merchant.
The purpose of § 507(a)(6) is to protect the innocent consumer who is unable to protect himself or herself. As stated in an opinion by Chief Judge


Q:

Can identification be confirmed over a mobile application, for alcohol consumption

I am in charge of hosting an event, here in California, and I had a quick question regarding the legality of an offer that was presented to me recently.
The event that we are hosting will be providing alcohol, however we will also be allowing minors (below 21) onto the premises. This will be a large event, and checking identifications on the way in is always tedious. Therefore a local tech firm has offered to integrate identification verification software that checks if the person is 21+ upon sign up of the event. Then at registration the participant is provided their package with a wristband if they are 21+.
Therefore, my question is if there is any legal implicationfederally
  recognized Indian tribe located in Washington, if the enrollment card
  incorporates security features comparable to those implemented by the
  department of licensing for Washington driver's licenses.

As far as I know, no state accepts proxies such as "wristband given by a party who checks IDs", or "photocopy of government ID".


values, although the decline in triglyceride concentrations was statistically significant. The distribution of apolipoprotein (a) [apo (a)] isoforms in subjects with type II diabetes mellitus was not unusual and the apo (a) isoform patterns did not change with improved metabolic control. Although the number of subjects was small, there was no decline in Lp(a) concentrations with improved control and thus the effect of glycemic control on Lp(a) concentrations may be much smaller in type II than in type I diabetes. These results suggest that diabetic subjects with elevated Lp(a) concentrations should have intensive management of conventional cardiovascular risk factors such as high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol (LDLC), and blood pressure.served to "cancel and terminate" the contract thereby disaffirming its continued existence. Powers is not now entitled to a deficiency judgment because to grant it would be to affirm the continued existence of the contract by holding Ford further liable under it.
A number of cases support our holding. For example, see Faysen Lake, Inc. v. Miller (1943), 130 N.J.L. 289, 32 A.2d 506; Abodeely v. Cavras (Iowa 1974), 221 N.W.2d 494; Wollenberger v. Hoover (1931), 346 Ill. 511, 179 N.E. 42, 57; Davies v. Boyd (1963), 73 N.M. 85, 385 P.2d 950; Gruskin v. Fisher (1979), 405 Mich. 51, 273 N.W.2d 893; and Solomon Iron and Metal Co. v. Bradford (1962), 33 Ill. App.2d 452, 179 N.E.2d 697; 77 Am.Jur.2d Vendor and Purchaser 602 at 732. Each case


theory based on affirmance by suing for damages for breach of the contract or for specific performance since one is precluded from pursuing inconsistent remedies. The remedy of the vendor by way of forfeiture of the contract and the continued liability of the purchaser for the purchase money are totally inconsistent and may not both be pursued."
221 N.W.2d at 498.
Finally, we note Gruskin v. Fisher, supra, where the court, though concluding a forfeiture *737 had not yet occurred, recognized the general rule that one may not forfeit a contract and thereafter expect to enforce it. The court observed that once a land contract seller had taken possession of the property pursuant to a forfeiture, he was no longer entitled to seek a foreclosure. In a concurring opinion, JusticeQ:

Is the plane of rotation of planets around the sun perpendicular to the Suns trajectory around the galactic center?

If yes why is it a coincidence or is it so in other systems, ?this would make for an interesting trajectory of planets taking in account their rotation round the galactic center..

A:

If that were so the visible galaxy would coincide with the ecliptic. On every clear night you can see that that is not the case. This builds on the fact that the sun moves in the galactic plane, like most stars. Note that the galaxy is not entirely flat though.


provide a surface suitable for adequately maintaining writing and/or reading materials thereon for use as a traveling desk top. Additionally, the exterior flat surfaces of such an attache case are likely to encounter foreign objects during use which result in deformations of the large flat surfaces thus hindering their usability as writing surfaces.
Existing box-like attache cases having provision therein for containing a separate writing surface are disclosed in the following U.S. Pat. Nos. 3,082,049; 3,104,289; 3,112,017; 3,833,098; and 3,904,003. However all of these patents disclose attache cases in which the major compartment of the case, defined by the half-shell-like lid and base, must be opened to have access to the writing surface, usually a removable board which is snapped or otherwise releasably attachable to the interior of thecontinuous variables. Proportions were compared using the chi-square test or Fisher's exact test, as appropriate. For dependent samples, a paired *t* test was used for normally distributed data, while the Wilcoxon signed-rank test was used for skewed data. Correlation between groups was assessed using Pearson's correlation coefficient. A *p* value of \< 0.05 was considered statistically significant.

Results {#Sec4}
=======

Demographic, clinical, and laboratory characteristics {#Sec5}
-----------------------------------------------------

Fifty female SLE patients were included, 25 each in the CYC and MMF groups. The mean (SD) age of study subjects at diagnosis and at the time of recruitment, marital and family status, obstetric and menstrual history, and serological markers of SLE disease activity have been summarised in Table [1](#Tab1){ref-type="table"}. Table 1Baseline characteristics of patients in the cyclophosphamide (CYC) and mycophenolate mofetil (MMF) groupsParameter\*CYC (***n*** = 25)MMF (***n*** = 25)Age at recruitment


FSH significantly increased, the levels of AMH and inhibin B decreased significantly (Table [2](#Tab2){ref-type="table"}). There was a non-significant increase in the levels of LH and a non-significant decrease in the levels of estradiol (Table [2](#Tab2){ref-type="table"}). In the MMF group, after 6 months, inhibin B levels showed an increase in the mean levels while the rest of the hormones (LH, FSH, estradiol, and AMH) did not show any significant change. Compared to MMF, the CYC group had significantly lower levels of estradiol, AMH, and inhibin B after 6 months of therapy. Table [2](#Tab2){ref-type="table"} shows the baseline and 6-month follow-up levels of various hormones tested in both groups. Serum levels of thyroid hormones, prolactin, and testosterone at baseline have been summarised in Table [1](#Tab1){ref-type="table"}. Table 2Markers of ovarian reserve (serum hormones, ovarian volume, and antral follicularof CYC on ovarian volumes in SLE has not been assessed prior to this study, although one study did find lower ovarian volumes in patients of SLE not previously exposed to CYC \[[@CR22]\]. AMH levels were found to be lower in SLE patients previously exposed to CYC, but doses as per the Euro-Lupus regimen were not found to affect AMH levels \[[@CR16], [@CR21], [@CR23], [@CR24]\]. Ma et al. found lower antral follicular counts in patients of SLE, but no difference was found in those with and without CYC therapy \[[@CR23]\]. In the absence of long-term follow-up data, the consequences of reduced ovarian reserve on subsequent fertility are difficult to predict. It would be interesting to see whether ovarian volumes remain persistently low leading to impaired fertility, or recover


was found. The exams were performed using a pelvic coil only in approximately 15 min. The CT and MRI scans of 20 consecutive patients who had received TRUS-guided permanent transperineal interstitial prostate 125Iodine or 103Palladium brachytherapy were evaluated using an in-house dosimetry system. To eliminate anatomical dependence, the MRI-derived DVHs for the entire calculation volume were then compared to those derived from the CT scans. The differences in isodose volumes, of the calculation volumes, for all implants at all dose levels were not statistically significant at the 95% confidence level. Calculation volume isodose volumes derived from MR images were statistically similar to those derived from CT images at the prescription dose for both 125Iodine (p < 0.01) and 103Palladium (p < 0.026). This study presents the first evidenceAlabama added the 22nd commitment to its 2019 class on Tuesday night in 4-star defensive end Braylen Ingraham of Fort Lauderdale (Fla.) St. Thomas Aquinas.

Ingraham ranks as the No. 22 strong-side defensive end and the No. 289 overall player in the country, per the industry-generated 247Sports Composite Rankings.

Nobody knows Ingraham's ability better than St. Thomas Aquinas head coach Roger Harriott. He provided insight into what makes the South Florida standout great.

"Braylen has been an asset on a holistic level," Harriott told BamaOnLine. "His even temperament has struck a balance of humility, confidence, and integrity. As a player, he is dominant between the whistles. His size, athleticism, strength, physicality, and speed have enabled him to be a formidable force against opponents."

That's high praise from a coach that's seen elite


you are denied access.

Biometric Passwords

The third level in passwords is the biometric password. This is the
use of non-reproducible biological features, such as fingerprints or
facial features to allow access. An example of this is the retinal
scan, in which the retina – which is the interior surface of the back
of the eye is photographed.

The retina contains a unique pattern of blood vessels that are easily
seen and this pattern is compared to a reference. Biometric passwords
are the most sophisticated and are considered 'safer' but in reality a
password that you 'carry' in your finger or eye is no safer than a
strong password that you carry in your head, provided that the
software that uses the
password is correctly configured.to Lower Canada
Category:Burials at Mount Hermon Cemetery


disclosed in Published Unexamined Japanese Utility Models Sho No. 52-16848 and Sho No. 52-16849 by the inventors of this invention.
Professional tennis players who usually hit the ball on the sweet spot have been requesting a sweet spot with a more effective elastic rebound. However, in conventional technologies, it is too costly to manufacture a string which can form such a sweet spot, thus the string is not practical to manufacture.
In order to solve the problems of conventional strings and stringed rackets with such strings, this invention provides a string which can provide a large sweet spot, and a stringed racket with such strings.
Another object of the invention is to provide a string which can improve the solidity of a ball rebounded from the sweet spot of a racketgames. It recently received a capital investment from Chinese conglomerate Tencent, but The Wonderful 101 Remastered plan precedes that agreement, and so that investment will not be used to fund the project.

"Support from players and fans is vital in making this happen. With your help, we can create these brand new additions to make The Wonderful 101: Remastered the definitive release you all deserve, and bring it to more platforms so everyone can enjoy," the studio said in the Kickstarter FAQ. "And of course, all additional content funded through stretch goals will be made available to backers for free!"

Original story:

Nier Automata developer PlatinumGames seems to be poised to announce something today. This morning, the Platinum Twitter account posted a link to a new site with the hashtag Platinum4.


And Reserve Tucked into the hillside of a 14-acre nature reserve, Gaia Hotel And Reserve has a plethora of nature and wildlife on its beautiful grounds. The hotel was originally founded as a conservation center for native orchids and endangered species.9601280

Gaia Hotel And Reserve Tucked into the hillside of a 14-acre nature reserve, Gaia Hotel And Reserve has a plethora of nature and wildlife on its beautiful grounds. The hotel was originally founded as a conservation center for native orchids and endangered species.

Oyster.com

Gaia Hotel And Reserve Gaia's Jungle View Studio, as you can imagine, has a breathtaking view of the lush jungle surrounding the property. The pool at the hotel overlooks the nature reserve below and the ocean in the distance.9601280

Gaia Hotel And Reserve Gaia's Jungle View Studio,a small cargo of woollens, blankets, iron bars, knives, nails, etc. and a supply of ornaments and baubles to the north-west coast of America, to barter with the ‘Red Indians’ in Canada for furs. The area was supposed to be a preserve of the South Sea Company, of London, but this did not seem to worry Cox and his friends in the least. Five hundred and sixty sea-otter skins were obtained and landed and sold at Canton for over £5,000”.  (or 20,600 Spanish dollars)
In 1786, trading under the fictitious name of the 'Austrian East India Company’ (a name supposedly pinched from the earlier legitimate company which had gone bankrupt in 1785), the partners bought in London a 400-ton ship called the Loudoun, fitted her out there and


merchant. When Andrew Reid invested in and became a partner in Meux's Brewery in 1793, Jack also became a partner.
In 1795 Jack married Ann Holland (1768 – 1848), the daughter of a clergyman. Meux's Brewery became Meux Reid, and after an acrimonious split with the Meux family in 1808, in 1816 became Reid's Brewery.
Jack lived at 48 Bedford Square, London, next door to his brother Andrew at no 46, and also owned Kingswood Lodge in Egham, Surrey. At his death on 11/4/1821 he was still the owner of 5 £10,000 shares in Reid's Brewery.

References

Category:Scottish merchants
Category:History of alcoholic drinksundoubtedly stirs lingering trauma for many who experienced the event first-hand. Some still struggle with how someone could be motivated to commit such a hateful crime.

Translation: During a commemoration ceremony at Parliament, the Medal of the National Assembly was awarded posthumously to the 14 women murdered on December 6, 1989, at Polytechnique. Here is the video of the National Assembly.

Do you believe enough has been done to honour the tragedy over the years?

"It’s important to remember the price paid by those 14 young women, full of promise, for simply wanting to learn and advance. There will always be more work to do in terms of evolving, but in the past 30 years, Polytechnique has worked to honour this tragedy and use it as a means to be progressive


display.getHeight();

AlertDialog.Builder builder = new AlertDialog.Builder(mContext);
builder. setPositiveButton("Dismiss",
                new DialogInterface.OnClickListener() {
                    @Override
                    public void onClick(DialogInterface dialog,int which) {
                    }
                }).setIcon(android.R.drawable.ic_dialog_info);
builder.setMessage(result);
Dialog dialog = builder.setView(new View(mContext)).create();
dialog.setTitle("Details");

dialog.show();

WindowManager.LayoutParams layoutParams = new WindowManager.LayoutParams();
layoutParams.copyFrom(dialog.getWindow().getAttributes());
layoutParams.width = displayWidth - 50;
layoutParams.height = displayHeight - 100;

// change position of window on screen
layoutParams.xas the targets. Local concentration of the desired sequence is quite high and can be detected with the fluorescent probes. One class of repeats is found in centromere and pericentromere regions of chromosomes \[[@B15-molecules-18-15357]\]. Their functions are not yet completely understood. They participate in sister chromatid segregation and cohesion and in the coordination of chromosome movement during mitosis, but there are also evidences that they could have many other unknown functions. The centromeres have two types of repeats: major and minor satellites. These repeated sequences cover several millions of base pairs. The major satellites are 10--20 times larger in number \[[@B15-molecules-18-15357]\]. Telomeres are localized at the ends of chromosomes; they play an important role in the cellular life cycle. Their length is shortened with cell ageing. The maintenance


factors using gene-engineering methods. In the beginning of the 2000s many laboratories were developing "zinc fingers", peptide structures that originate from the DNA-binding domains of eukaryotic transcription factors ("zinc proteins") containing zinc ions linked to helical peptide structure through two histidines and two cysteines or through four cysteines \[[@B51-molecules-18-15357],[@B52-molecules-18-15357],[@B53-molecules-18-15357]\]. Using gene engineering, specific fluorescent probes for live cell imaging in plants (*Arabidopsis*) and centromere repeats in mouse were constructed from a specific polydactyl zinc finger fragments fused with the green fluorescent protein (GFP) \[[@B54-molecules-18-15357]\]. However, currently, zinc fingers are progressively replaced by new sequence-specific peptides called transcription activator-like effectors (TALE). These proteins come from transcription factors of plant bacteria *Xanthomonas spp* that are able to change genetic expression in the host plants \[[@B55-molecules-18-15357],[@B56-molecules-18-15357]\]. Each element of a TALEwork of Hsu and Dervan \[[@B104-molecules-18-15357]\] to determine polyamide concentration in cells, as well as a recent publication by Peng *et al*. \[[@B110-molecules-18-15357]\], who have used a non-specific minor groove binding probe different from sequence-specific polyamides.

3. Choice of Approaches and Fluorophores for Live Cell Applications
===================================================================

As it has been already mentioned, an important requirement for living cell observations is a possibility to detect a real signal from target-bound probes on the background fluorescence of non-bound molecules that penetrate into cells. It is a problem for both DNA and RNA *in cellulo* detection.

In order to circumvent the problems of the high fluorescence background, several approaches have been proposed. The first way is to use single linear probes and fluorophores that change their fluorescence spectra upon interaction with the target DNA,