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Vikings released this rendering in November of their potential Arden Hills stadium.

, Credit: Minnesota Vikings

Vikings told Arden Hills site not workable for stadium

Article by: BAIRD HELGESON

Star Tribune

January 9, 2012 - 9:24 AM

The Dayton administration and legislative leaders are quietly and at times forcefully telling the Minnesota Vikings that the $1.1 billion Arden Hills stadium plan is unlikely to work, sources close to the negotiations say. That advice has prompted team officials to re-examine previously spurned sites in Minneapolis.

The subtle signs of shifting momentum on potential stadium sites are increasingly apparent.

Vikings officials have conducted traffic studies of the Linden Avenue site, near the Basilica of St. Mary, and discussed the site in a recent meeting with new Senate Majority Leader Dave Senjem. Last week, team officials also got a


House author of stadium legislation, said plans are under way to retool the Arden Hills proposal before Dayton's deadline to make it more appealing.

The changes could require a bid process to choose a developer for the 170 acres of land surrounding the stadium. The current plan would allow team owner Zygi Wilf to develop the property. But that change would not address a chief complaint -- the lack of a local funding source.

Nick Riley, Ramsey County's chief lobbyist, said it is unnerving to see the Vikings' obvious interest in Minneapolis sites.

Riley said he doesn't believe the Vikings are abandoning Arden Hills, but said, "Frankly, if it is Minneapolis, so be it."

Jockeying for favor

In Minneapolis, community leaders are showing fresh zeal for keeping the team and jostling privately tohe wrote. The letter notes that major construction would "do harm to our buildings" and parking for Sunday games would prove "daunting."

The biggest question for a Minneapolis site may be whether Rybak has the political muscle to persuade a skeptical City Council to support the use of tax dollars for a new Vikings home.

Rybak "still governs a city with lots of other challenges," Horner said. "Even in a year with minimal city property tax increases, a lot of Minneapolitans aren't going to happily accept public subsidies for a stadium."


Q:

Vertical / Horizontal Scaling Disk Size MySQL or MariaDB

I have been looking into this for a while and cannot find a suitable solution so would like to know if someone here can please help.
I am trying to set up database back-end that will assist with doing analytics. I need to stick with MySQL or MariaDB as this is what we currently use on all projects and queries.
My problem is that I have access to a few virtual machines. Most of them pretty decent, but they all have a range and capacity of 1-2TB. They cannot be increased in disk size as they have been provisioned and in use for other purposes as well.
As they are only used infrequently and sitting idle for large amounts of time I am                       -5-

[*5] form” television advertisements (approximately two minutes long), to market

its products.

      B.        Restore 4

      Petitioners incorporated Restore 4 on January 30, 1997. They initially

capitalized Restore 4 with funds from Sirius. Restore 4 sold the same products as

Sirius. They incorporated Restore 4 because Sirius could not market its products

using the various direct response companies, such as the Home Shopping Network

and QVC. The operating companies operated out of the same facility, and they

shared a common labor force.

      Restore 4 sold Zap under the name “Restore


for Mr. Wycoff, Mr. Nunes examined compensation paid to

individuals acting as the CEO of comparable companies.

        Petitioners had identified the operating companies’ primary business

activity as the production and sale of household chemicals. Therefore Mr. Nunes

determined that the operating companies’ peer group was companies that had

reported financial information from 1999-2003 in the following Standard

Industrial Classification (SIC) codes: 2841 (soap, detergents, cleaning

preparations, perfumes, cosmetics); 2842 (speciality cleaning, polishing and

sanitation preparations), and 2844 (perfumes, cosmetics, and other toilet

preparations). After reviewing the financial data of the peer group companies he

excluded companies with less than $5 million and more than $200 million in
                       group did not set

executive compensation at unreasonably low levels. All 24 companies had annual

revenue below $200 million and were not pharmaceutical companies. In

comparing executive compensation between the peer group and the broader group

of 24 companies, Mr. Nunes used only cash compensation. He did not include

stock option compensation because he determined that stock option compensation

was not used in the industry and was “a meaningful source of CEO compensation

only at larger companies.” Mr. Nunes found that the peer group did not omit

highly compensated individuals but rather included some of the most highly
                                      -


for 2003 was

not appropriate. Instead he calculated that the operating companies would pay a

CEO baseline compensation of $109,000, which was the lowest salary a CEO in

the peer group received for 2003.13

      After calculating baseline compensation, Mr. Nunes considered whether

baseline compensation should be increased to account for unique characteristics of

      13
        The company that had the lowest CEO salary for 2003 also had the lowest
revenue of the peer group. The operating companies had revenue of less than $10
million in 2003. In 2003 the company with the lowest revenue had revenue of
approximately $20 million.
                                      - 24 -

[*24] the operating companies and Mr. Wycoff. Mr. Nunes decided that a 20%

cost of living adjustment was appropriate because of the location of the operating

companies. He then determined that a 10% decrease in baseline salary for 2002

and 2003 was appropriate14 because of revenue declines and a 20% increase in

2001 was appropriate because the operating companies had performed well.15 He

found that Mr. Wycoff’s tenure, experience, and education were typical of other

CEOs in the peer group and no adjustment for individual characteristics was

necessary. Mr. Nunes therefore concluded that the reasonable total compensation

for Mr. Wycoff’s services was $1,338,000, $654,000, and $118,000 for 2001,

2002, and 2003, respectively.


complete and accurate data is available for

the taxable year under review, the taxpayer’s industry is affected by business

cycles, or the product being examined is affected by a life cycle. See id. Data

from one or more years before or after the taxable year under review must

ordinarily be considered for purposes of applying the CPM. Id.

      Mr. Nunes applied the CPM, which generally requires the use of data from

one or more years. Mr. Nunes had complete and accurate data available from the

operating companies’ and Albion’s records. Additionally, Mr. Nunes determined

and petitioners admitted that the operating companies were affected by

macroeconomic recession and the products sold had a defined life cycle.

Therefore, the use of multiyear data was appropriate.
         disregard. Sec. 6662(c); sec. 1.6662-

3(b)(1) and (2), Income Tax Regs. “‘Negligence’ also includes any failure by the

taxpayer to keep adequate books and records or to substantiate items properly.”

Sec. 1.6662-3(b)(1), Income Tax Regs. Disregard of rules or regulations “is

‘careless’ if the taxpayer does not exercise reasonable diligence to determine the

correctness of a return position” and “is ‘reckless’ if the taxpayer makes little or

no effort to determine whether a rule or regulation exists, under circumstances

which demonstrate a substantial deviation from the standard of conduct that a

reasonable person would observe.” Id. subpara. (2); see also Neely v.

Commissioner, 85 T.C. 934, 947 (1985). An understatement means the excess of

the amount of the tax required to be shown on the return over the amount of the

tax imposed which is shown on the return,


reduced by any rebate. Sec.

6662(d)(2)(A). An understatement is substantial in the case of an individual if the
                                        - 54 -

[*54] amount of the understatement for the taxable year exceeds the greater of

10% of the tax required to be shown on the return or $5,000. Sec. 6662(d)(1)(A).

      The accuracy-related penalty does not apply with respect to any portion of

the underpayment for which the taxpayer shows that there was reasonable cause

and that he or she acted in good faith. Sec. 6664(c)(1). The decision as to whether

athey had reasonable

cause or acted in good faith with respect to the NOL. Therefore, with respect to
                                       - 56 -

[*56] that portion of the underpayment, petitioners are liable for accuracy-related

penalties under section 6662(a).

      We next address whether petitioners reasonably relied on the advice of tax

professionals with respect to setting the management fees paid to Albion.

Petitioners sought the advice of Marshall & Stevens ESOP Capital Strategies

Group, Barry Marlin, and Roland Attenborough to determine the proper

management fees that the operating companies should pay Albion. To determine

the management


which the company asserts is 61.8 percent higher than the median US salary of $52,461. Glassdoor found “Software Engineer” to comprise the most prevalent job pertinent to distributed ledger technology, estimating such to account for 19 percent of all open positions as of August 2018.

Many of Linkedin’s findings are consistent with those made by Glassdoor, with the company’s report also finding New York City and San Francisco to be the leading cities for open blockchain positions, equating for 24 percent and 21 percent of positions respectively. Glassdoor also asserts IBM and Consensys to list the most jobs in the distributed ledger technology sector, estimating that both companies are responsible for 12 percent of the open positions each.

Do you think that jobs within the distributed ledger technology sector willFaint hope

Like the sun, shrouded

Seeking the balcony

Like the little Buddha

An outline in the shadows

But faint hope

Is a far cry

From no hope

And that

Is where

You were

So hold out

For the fog to clear

So listen

For the love within

Build true hope

From faint hope

Inner light

Can not be

Diminished


" Don't upset your mother!" "She has to be handled with care." "What's that?" "An anti-fog spotlight." "I'm gonna try it out Sunday." "Look at your son!" "All flour-faced!" " l'm not in the mood!" " l was hoping you were!" "And my change?" " l need money forthe cafeteria." "Ask your dad." "Go on." "Here, Mama." "A storm's brewing!" " Papa, forthe cafeteria..." "What?" " l need 1,000 francs." "Ya ask for 1,000 and hope for 500." "So ya only need 300." "Here's 100." "Take 500." " Thanks." " But your mom's supposed to pay that." " The scissors!" "Where are the scissors?" "Aren't you clever!" "It's not funny!" "No homework now!" "It's time to eat." " Right!" "Each thing has its time and place." "That way,I rest." "Where?" " l'm going to see Huguette." " But I'm the race organiser!" " l'm sick of housework" "And dates in the afternoon!" "What?" " l mean the edible kind!" "Antoine, what're you waiting for?" "Go to bed!" " G'night!" "You can be so stupid!" " lf you could only take a joke..." "Your auto races are a waste of time!" "Antoine, the garbage!" "Lights out as soon as you're in bed!" " OK." " l make contacts!" "One day I'll be vice-president!" "[radio sighing off]" "[baby crying]" " Hurry up!" "It's late!" "We didn't hearthe alarm." " That I would have dirtied the classroom walls!" " There's no socks around these holes!" " Buy a new pair!" "The others are in the laundry." " l


the Pigalle fountain in 1 hour." " OK." "Bye." " Bye." "It's my uncle's old print shop." "The floor collapsed under the heavy machines." "Will it collapse again?" " lt can't fall any lower." "You'll be warm here." "Amattress..." "This'll do for a pillow." "It's real heavy!" "Go for a walk till midnight." " Keep my satchel until tomorrow." " OK." " "Dear Parents..." "I understand the seriousness of my lie."" "Why'd he kill me instead of you?" "A matter of preference!" ""Life between us is impossible." ""So I'm going to try my luck in the city or elsewhere." ""l want to become a man." ""When I see you again, we'll have a full explanation." "I close with kisses..." "Antoine."" " lt's normal that he hates me?" "You're"The tip of the tongue between the teeth..." "Father." "As if you're lisping." "Father." " "Fahzer."" " No!" " l can't." "Not everyone can use their tongue like you said." " Quiet!" "S..." "Si..." "Go sit down!" "lmpudent!" "Now you!" "Now you, answer me!" "Where is the girl?" " The girl has "bitch."" " No." "Beach." " Beach." "[knocking]" " The beach." "The beach." "Doinel?" " Doinel." " Sit down." "Frochot, take over until I return." "We don't know howto handle him!" "My husband" " Madam, you don't deserve such a rascal." "Ah..." "My poor baby!" "At least you're OK." "Where'd you spend the night?" " ln a print shop." "At a printer's?" "I don't care if he's last, so long as he behaves!" " Fine!" "Maybe it's...glandular."


Michelin." "Amillion'd be great!" " My dad would kill me because of that horse." "With a million we'll find a beach, open a boat business and no one'll bother us!" " Make up your mind." " Dad's office has some." " Don't back down!" "We can't sell it." "They're numbered." "We won't sell it, we'll pawn it!" " Smart!" " Ma pawned all our stuff." "Alright!" "Ha-ha-ha-ha!" " Bravo!" " Little Red Riding Hood in my arms!" "[kissing sounds]" " How much?" " 10% ." " OK." " 1,000 right away." "When you come back!" "You sure trust me!" " Hey!" "Give us back our typewriter!" "Runnin' away?" "!" " l thought you'd gone this way." " Sure!" " They wouldn't take it!" " Then give it back!"she never did!" "She gave me a very nice book that day." "My mother would always go through my pockets, and my pants were on the bed that night, so she came in and swiped the money, 'cause the next day it was gone." "Then she made me confess I'd taken it from my grandma." "So she took away the book Grandma had given me." "One day I asked to read it... and found out she'd sold it." "Your parents say you always lie." " l lie...once in a while." "At times, if I told the truth, they wouldn't believe me!" "So I tell lies." " Why don't you love your mother?" "At first I was placed with a foster mother." "When the money ran out, I went


Cyclodiene insecticide resistance: from molecular to population genetics.
This review follows progress in the analysis of cyclodiene insecticide resistance from the initial isolation of the mutant, through cloning of the resistance gene, to an examination of the distribution of resistance alleles in natural populations. Emphasis is given to the use of a resistant Drosophila mutant as an entry point to cloning the associated gamma-aminobutyric acid (GABA) receptor subunit gene, Resistance to dieldrin. Resistance is associated with replacements of a single amino acid (alanine302) in the chloride ion channel pore of the protein. Replacements of alanine302 not only directly affect the drug binding site but also allosterically destabilize the drug preferred conformation of the receptor. Resistance is thus conferred by a unique dual mechanism associated with alanine302, which is theonly residue replaced in a wide range of different resistant insects. The underlying mutations appear either to have arisen once, or multiply, depending on the population biology of the pest insect. Although resistance frequencies decline in the absence of selection, resistance alleles can persist at relatively high frequency and may cause problems for compounds to which cross-resistance is observed, such as the novel fipronils.


than May’s. The EU has said it would only allow an extension for a clear purpose. Corbyn asked May what it is. She replied he would know if he had listened to her first answer.

Corbyn said May proposed meaningful vote 3 (MV3). But the Commons rejected this and accused May of being reckless. May said she had no idea what Labour wanted. She said she was opposed to a long extension. It would mean taking part in the European elections, and it would mean days of the Commons contemplating its navel on Europe. She said the Commons had indulged itself on Europe for too long.

May accused Corbyn of disrespecting democracy by wanting to hold a second referendum. Corbyn said Wednesday marked 1,000 days since the referendum. May washas abandoned a stance she was defending just last Wednesday (see 10.32am) and, even though she has U-turned under pressure from Brexiters, they were damning, horrified at the prospect of even a short article 50 extension. (Eg, see Peter Bone at 12.27pm and Richard Drax at 12.45pm.) But remainers were damning too. In fact, on Brexit, not a single MP stood up to defend her.

Jeremy Corbyn’s broad-brush critique was perfectly sound, but his decision to start by asking for a meeting today was ill-advised (because May was entitled to respond that he has been dodging a meeting for weeks) and, considering the extent of May’s humiliation, he did not really make the most of the opportunity available. Ian Blackford’s questions were more focused. But the most memorable interventions


quadratic (dashed line in the blue band) and linear (dashed line in the green band) fits in $M^{-1}$. Note that the errors of the continuum values are now correlated and this correlation is taken into account in the fits. The quadratic fit [eq. (\[e:ratio\_EFT\])]{} has a correlated $\chi^2/{\rm dof} = 16.0/2$ and the linear fit has $\chi^2/{\rm dof} = 7.6/2$. None of the fits work well although it seems that the quadratic fit describes better the curvature in the data.

![Left: continuum extrapolations of the ratio $R=\sqrt{t_c/t_0}$ using a global fit [eq. (\[e:globfit\])]{}. The symbols and lines are like in [Fig. \[f:t0tc\_noglob\]]{}. Right: the continuum values plotted against $\Lambda/M$. The lines in the bands are like in [Fig. \[f:t0tc\_noglob\]]{}. Note that the continuum data are correlated unlike in [Fig. \[f:t0tc\_noglob\]]{}.[]{data-label="f:t0tc_glob"}](t0tc_contlim "fig:"){width="7cm"} ![Left: continuum extrapolationsendoscope has a large working channel of 3.8 mm and is equipped with an Albarran lever.

### Needles and accessories for drainage {#sec3-2}

Using a 19G FNA needle (Wilson-Cook Corporation), a 0.035-inch guidewire can be inserted through the needle into the dilated bile duct. However, one of the main problems during these new techniques mainly hepaticogastrostomy is the difficulty manipulating the wire guide through the 19 gauge EUS needle. The main issue was "stripping" of the wire coating, which in turn created a risk of leaving a part of the wire coating in the patient and also the impossibility of continuing the procedure and inserting the stent. To solve this problem, we worked with Cook Medical to design a special needle called the EchoTip^®^ Access Needle\* \[[Figure 2](#F2){ref-type="fig"}\]. This needle


that the official tf.data API isn’t perfectly backward compatible. The total number of changes isn’t large, but most of them are in strategic, commonly used functions, so there’s a fair chance existing code will break.

For example, if you previously used tf.contrib.data.rejection_resample(), or tf.contrib.data.Iterator.from_dataset(), both of those have been modified—the former has a new function signature, and the latter has been removed entirely and replaced with the Dataset.make_initializable_iterator() function. TensorFlow’s documentation has other details about how to migrate away from tf.contrib.data and use the official tf.data library instead.

TensorFlow Estimator simplified

Many of the other additions build on TensorFlow’s reputation for convenience. A train_and_evaluate function provides a simple way to run TensorFlow’s Estimator (used to automatically configure common model parameters) in a distributed fashion across a cluster. Also, TensorFlow’s built-in debuggingincubated with 1 µg of the corresponding antibody (overnight at 4°C) followed by addition of 40 µL of 50% protein A/G (2 h at 4°C). After washing two times with ILB, the pelleted beads were resuspended in Laemmli sample buffer. Proteins were analyzed by 10% SDS-polyacrylamide gels, followed by Western blotting.

Small Interfering RNA (siRNA) Silencing of Gene Expression {#s2f}
----------------------------------------------------------

Chemically synthesized double-stranded siRNA duplexes (with 3′ dTdT overhangs) were purchased from Santa Cruz Biothecnology for the following targets: β-arrestin 1 (5′-AAAGCCUUCUGCGCGGAGAAU-3′), β-arrestin 2 (5′-AAGGACCGCAAAGUGUUUGUG-3′, 5′-AAAGCCUUCUGCGCGGAGAAU-3′, 5′-AAGGACCGCAAAGUGUUUGUG-3′), Rictor (5′-CACUUCGAUUAGUCAGAAA-3′, 5′-CGCUUACUUUGCCUAACAA-3′, 5′-CCAACUGAGUGCAAUAUGU-3′), c-Src (5′-CUCGGCUCAUUGAAGACA-3′, 5′-UGACUGAGCUCACCACAAA-3′, 5′-CCUCAUCAUAGCAAUAACA-3′, 5′-GUAGAUUUCAGAUGACUAU-3′). A non-silencing RNA duplex was used as a control for all siRNA experiments. Cells were transfected with Lipofectamine 2000 (Invitrogen; Carlsbad, CA, USA), according to manufacturers\' instructions. Silencing was quantified by immunoblotting. Only experiments


ghrelin stimulation. Transfection with Gβγ sequesters, β-ARK-CT, decreased the effect of ghrelin on Akt phosphorylation at both residues, indicating the involvement of the βγ-subunit of G proteins ([Fig. 1B](#pone-0004686-g001){ref-type="fig"}). Pretreatment with the PI3K inhibitor wortmannin (1 µM, 30 min) decreased the ghrelin-induced Akt phosphorylation at both residues ([Fig. 1B](#pone-0004686-g001){ref-type="fig"}).

![Role of G~i/o~ proteins, Gβγ dimers and PI3K in Akt phosphorylation in response to ghrelin.\
A, Time-course of the effect of ghrelin on Akt HM (S473) and A-loop (T308) phosphorylation. B, Ghrelin-induced Akt phosphorylation in the absence or presence of PTX (100 ng/mL, 12 h), PI3K inhibitor wortmannin (1 µM, 30 min) and βγ sequester β-ARK-CT. In A and B, serum-starved HEK-GHSR1a cells were treated with ghrelin (100 nM) at 37°C for the indicated times. Cells were lysed and analyzed byand β-arrestins in 3T3-L1 preadipocyte cells {#s3e}
-------------------------------------------------------------------------------------

As shown in [Figure 5A](#pone-0004686-g005){ref-type="fig"}, both Akt A-loop (T308) and HM (S473) phosphorylation reached maximal levels within 20--60 min of ghrelin addition (100 nM). The Akt phosphorylation was inhibited at both residues by pretreatment with PP2 (5 µM, 30 min) ([Fig. 5A](#pone-0004686-g005){ref-type="fig"}). Immunoprecipitation of ghrelin-treated cells (100 nM, 10 min) with antibodies for β -arrestin 1 or β-arrestin 2 coprecipitated full-activated Akt showing an increase on tyrosine phosphorylation compared to untreated cells ([Fig. 5B](#pone-0004686-g005){ref-type="fig"}). Furthermore, the activated form of Src, pSrc (Y416), co-immunoprecipitated with β-arrestin 1 or β-arrestin 2 ([Fig. 5B](#pone-0004686-g005){ref-type="fig"}).

![Src and β-arrestins regulate Akt phosphorylation in response to ghrelin in 3T3-L1 preadipocyte cells.\
A, Effects of the Src inhibitor PP2 and its negative control, PP3, on the ghrelin-induced Akt activation in 3T3-L1


preadipocyte cells. Serum-starved cells were pretreated with PP2 (5 µM, 30 min) or PP3 (5 µM, 30 min) before ghrelin stimulation (100 nM) for the indicated time periods. Akt phosphorylation was quantified by densitometry and expressed as a percentage of the maximal phosphorylation at HM (S473) and A-loop (T308) (mean±S.E of three independent experiments). B, Effect of ghrelin on the assembly of complexes containing β-arrestins 1 and 2 and pAkt. Preadipocyte 3T3-L1 cells were incubated with ghrelin (100 nM, 10 min) at 37°C, lysed and immunoprecipitated (IP) with antibodies to β-arrestins 1 and 2, and then analyzed by western blotting with pAkt HM (S473), pAkt A-loop (T308), pY, pSrc (Y416) antibodies. For A and B, western blots are representative of three independent experiments.](pone.0004686.g005){#pone-0004686-g005}

Discussion {#s4}
==========

The present study offers threea second signaling pathway is mediated by β-arrestins 1 and 2 involving the recruitment of GHS-R1a, c-Src and Akt into an β-arrestin-scaffolded complex ([Fig. 6](#pone-0004686-g006){ref-type="fig"}). Thus c-Src functions as a switch that initiates the Akt pathway associated to both the G~i/o~-protein dependent pathway and β-arrestin-scaffolded complex.

![Model of upstream activation of Akt by ghrelin.\
Binding of ghrelin to GHS-R1a activates the generation of the second messenger PtdIns(3,4,5)P~3~ (PIP3) by PI3K activation through G~i/o~-protein dependent signaling pathway. Akt translocates to the plasma membrane by binding to PIP3 where it is phosphorylated at Y by the membrane bound c-Src. This phosphorylation (Y) is followed by phosphorylation of Akt A-loop (T308) and HM (S473) by PDK1 and mTORC2 respectively. Once the receptor is activated, a second signaling pathway is mediated by β-arrestins 1


and 2, involving the recruitment of GHS-R1a, c-Src and Akt into an β-arrestin-scaffolded complex.](pone.0004686.g006){#pone-0004686-g006}

We thank Prof. R.J. Lefkowitz for antibody against β-arrestins (Howard Hughes Medical Institute and the Departments of Medicine and Biochemistry, Duke University Medical Center).

**Competing Interests:**The authors have declared that no competing interests exist.

**Funding:**This work was supported by grants from Instituto de Salud Carlos III (Ministerio de Ciencia e Innovacion: PI060239, PI060705, PI070908), and Xunta de Galicia (PGIDIT05BTF20802PR, PGIDIT06PXIB918322PR, PGIDIT06PXIB918360PR). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The work of M Lodeiro is funded by Instituto de Salud Carlos III (Ministerio de Ciencia e Innovacion). The work of M Theodoropoulou was supported by a research fellowship at the University of Santiago de Compostelacontrol points (GCPs). However, in spite of these advances, MMS remains prohibitively costly for many applications and requires extensive technical expertise. In this regard, low-cost unmanned airborne vehicles (UAVs) equipped with directly georeferenced passive- and active-imaging systems are emerging as alternative mobile-mapping platforms that can suit the needs of several applications such as precision agriculture. To that end, UAV-based MMS are gaining tremendous interest from researchers in the mapping and plant-science fields to satisfy needs such as precision agriculture, high-throughput phenotyping, etc.
Precision agriculture has become an important activity for 1) optimizing crop yield given diminishing resources, 2) increasing the reliability of crop-yield prediction, and 3) reducing the agricultural impact on the environment through efficient use of fertilizers and pesticides. Technologies are also being adapted for advanced plant breeding


where phenotypic data are obtained to quantify plant growth, structure, and composition at multiple scales over the growing season. Traditional phenotyping has primarily been conducted in field-based plots, which is time-consuming, labor-intensive, and includes destructive sampling.
To obtain a rich set of structure and chemistry based traits, airborne vehicle platforms are being equipped with RGB cameras and hyperspectral scanners. RGB cameras provide high geometric resolution for accurate localization and estimation of important plant traits such as height, canopy closure, and leaf structure. Hyperspectral scanners with fine spectral resolution provide useful data for the estimation of canopy nitrogen, chlorophyll content, and various narrow-band vegetation indices. Due to the volume of collected data, in general, RGB cameras implement frame arrays whereas hyperspectral scanners are most commonly based on a linear arrayVS's main window doesn't, and things like the editor don't have win32 horizontal scrollbars, they'll refuse to send horizontal scroll messages.  This one is unfixed.
(Definitely not your case, but) VMWare Fusion (on OS X) running windows doesn't forward on horizontal scroll events to the client OS.

I'll check with people to see if the MX1100 is known or falls into either of the first two categories.

A:

Try out my solution with AutoHotKey:
https://superuser.com/a/1144201/240650
; Shift + Wheel for horizontal scrolling
+WheelUp::
    ; Scroll to the left
    MouseGetPos,,,id, fcontrol,1
    Loop 8 ; <-- Increase for faster scrolling
        SendMessage, 0x114, 0, 0, %fcontrol%, ahk_id %id% ; 0x114 is WM_HSCROLL and the 0 after it is SB_LINERIGHT.
return
+WheelDown::


 ;Scroll to the right
    MouseGetPos,,,id, fcontrol,1
    Loop 8 ; <-- Increase for faster scrolling
        SendMessage, 0x114, 1, 0, %fcontrol%, ahk_id %id% ;  0x114 is WM_HSCROLL and the 1 after it is SB_LINELEFT.
return

Q:

Can't assign to operator

i = 0
num = 0
while i <= 1000:
    if i % 3 and i % 5 == 0:
        num + i = num <--- Adding Up Numbers Divisable by 3 & 5...
    i += 1
print num

Error:* can't assign to operator (line 5)

A:

Are you sure you don't want:
num = num + i

or equivalently:
num += i

?
Note that this can be done  a little easier using sum, range and a generator expression:
sum( x for x in range(0,1000,5) if x % 3 == 0 )
                            #^only take every


were not attached to any particular company but held general supervisory positions.  The lockbox keys for all of the companies were interchangeable;  thus, any company officer on E-Block would have been able to open another company's lockbox with his own set of keys and thereby gain access to that company's control panel.

7
On September 4, 1991, Armitage was the sergeant in charge of E-Block;  he had held that position for some two years.  Fischl had been housed on E-Block's "Four Company" since late August 1991.  His cell was the 17th away from the officer's cage.  Marshall was the officer in charge of Four Company;  Marshall was not regularly assigned to E-Block, and September 4 was the only day he worked there.  This reasoning was flawed.  Fischl does not seek to recover for the postattack threats;  he seeks to recover for the assault.  Armitage's bringing two of the attacking inmates with him when he visited Fischl in the hospital, discussing the assault, and threatening Fischl with further harm are admissible to show Armitage's collaboration with Fischl's attackers.  And Armitage's warning Fischl not to bring charges against "us" is admissible to show Armitage's own acknowledgement of his involvement.

42
Accordingly, this testimony would be admissible at trial and, if credited by the jury, would suffice to permit a finding of the personal involvement of Armitage.  The jury would of course be free to disbelieve Fischl's testimony, but the assessment of his credibility is within the province of


Second, this statement would not be offered for the truth of its contents, see Fed.R.Evid. 801(c), but rather for the simple fact that Armitage made a preattack statement to the inmates with regard to the assault, revealing his foreknowledge and endorsement of the assault.

45
The statement of Fuquan that it was the "sergeant" who had instructed him, which is the statement the district court concluded was hearsay, is subject to a different analysis.  While that statement would be offered for the truth of its content, i.e., that it was in fact Armitage who had made the preattack statement to the inmates, we would view it as falling outside the definition of hearsay because it was the statement of a coconspirator in furtherance of the conspiracy, see Fed.R.Evid. 801(d)(2)(E).On June 24, 2016, at the headquarters of the National Front in Nanterre, France, Marine Le Pen hosted an impromptu press conference to celebrate the result of Britain’s referendum on EU membership. “What no one had envisaged a few months ago is now a reality that must be acknowledged by all: Yes, it is possible to leave the European Union,” she said. A poster of two fists, breaking free of their heavy chains, plastered the wall behind her. “Et Maintenant La France!” the caption read: And now France.

As Le Pen spoke, fellow travelers across Europe took to Twitter to express their euphoria. “All I want to say: THANK! YOU!! #NigelFarage For #Brexit and #Independenceday,” wrote Beatrix von Storch, leader of the far-right Alternative for Germany. “Hurray for the


spinnerDuration int 1500 The spinner animation duration in miliseconds

CustomSliderWidths parameters #

Parameter Default Description trackWidth double progressBarWidth / 4 The width of the slider's track. progressBarWidth double slider's size / 10 The width of the slider's progress bar. shadowWidth double progressBarWidth * 1.4 The width of the slider's shadow. handlerSize double progressBarWidth / 5 The size of the slider's handler.

CustomSliderColors parameters #

Parameter Default Description trackColor Color #DCBEFB The color of the slider's track. progressBarColor Color The color of the slider's progress bar. Won't be used if the slider uses gradient progressBarColors != null progressBarColors List [#1E003B, #EC008A, #6285DA] The list of colors for the progress bar's gradient. gradientStartAngle double 0 The start angle for the progress bar's gradient. gradientEndAngle double 180 The end angle for the progress bar's gradient.A simple elimination of clonogenic tumor cells from human bone marrow in vitro by heat: its application to autologous bone marrow transplantation for B-cell lymphoma.
The application of hyperthermia to the treatment of neoplastic disease has focused on solid tumors. Since the hyperthermic sensitivity of human B-cell lymphoma cells is not known, we have examined the effect of hyperthermia on the growth of B-cell lymphoma cell lines (Raji and Daudi) in vitro to evaluate the ability to purge tumor cells from normal bone marrow by heat, utilizing a limiting-dilution assay to measure log depletion of tumor cells in a 20-fold excess of normal bone marrow. When exposed at 42 degrees C and 43 degrees C for 120 min, both clonogenic Raji and Daudi cells were dramatically decreased (a 4-


Q:

Codecepetion Acceptance Test with self signed SSL

I am trying to login to my app using WebGuy. I created a Cept file MergeCompaniesCept.php with contents:
$I = new WebGuy($scenario);
$I->wantTo('login into admin, merge companies, & verify data');
$I->amOnPage('/login.php');
$I->fillField("username","name");
$I->fillField("password","xxxxxxxxxxxxxxxxx");
$I->click("LOGIN");

But I get the following error:
[Codeception\Exception\ModuleConfig]
Codeception\Util\Mink module is not configured!                                entered, or attempted to enter, Switzerland illegally. According to data reported by Swiss television, the new measures have made a notable difference in the effectiveness of border security, with some 70% of illegal being sent back to Italy, as opposed to only 10% up to a month ago.

The migrants’ new itinerary takes migrants through northern Italy’s beautiful Great Lakes region, in the foothills of the Italian Alps.

Migrants caused a media stir earlier this month after setting up a makeshift camp around the San Giovanni train station at the southern tip of Lake Como, vacation home to such celebrities as George Clooney.

A vocal spokesman for open European borders to migrants, Clooney came under fire earlier this year for the apparent inconsistency between his demands for privacy in his 22-room


analysis showed abnormal nuclear retention and apparent co-localizations of RanGAPl with NUP205 and NUP205 with NUPl07, meanwhile, GP210 with NUP205 mainly co-localized in the nuclear envelope (NE) of motor neurons. Furthermore, RanGAP1, GP210 and NUP50 showed similarly abnormal nuclear precipitations and cytoplasmic upregulations in SOD1-Tg mice and ALS patients, moreover, aberrant co-localizations of RanGAP1 with TDP-43 and NUP205 with TDP-43 were also observed in motor neurons. The present study indicated that the mislocalization of these proteins of NPCs may underlie the pathogenesis of ALS both in SOD1-Tg mice and human sporadic ALS patients, and these dysfunctions may be a fundamental pathway for ALS that is not specific only in C9-ALS but also in SOD1-ALS, which may be amenable to pharmacotherapeutic intervention.$p(\theta)$ often circumvents many complexities of $p(x)$, potentially allowing it to be known in analytical form *a priori*. Also, the distribution over parameters corresponding to a set $\mX$ is independent of whether $x\!\in\!\mX$ are labelled, thus empirical distributions over model predictions should be similar for labelled and unlabelled data, whereby the former provides a prior for the latter. We formalise this within a probabilistic model for *discriminative* semi-supervised learning that underpins a family of SSL methods that rely on properties of $p(\theta)$ rather than $p(x)$. The explicit form of $p(\theta)$ is considered in several cases, including classification where classes are mutually exclusive and $y|x$ deterministic, i.e. where every $x$ is only ever associated with a unique $y$ (despite any epistemic uncertainty as to which), as applicable to popular


$x$ varies. State-of-art models [@berthelot2019mixmatch; @berthelot2019remixmatch] combine methods of both types. A canonical SSL method that relies on explicit assumptions of $p(x)$ is the classical generative model: $$p(\mX^l, \mY^l, \mX^u)
    =
    \int_{\psi, \pi} p(\psi, \pi) p(\mX^l|\mY^l, \psi)p(\mY^l | \pi)
    \underbrace{{\sum}_{\mY^u\in\mathcal{Y}^{N_u}}p(\mX^u| \mY^u, \psi)p(\mY^u |\pi)}_{p(\mX^u|\psi, \pi)}
    \label{eq:ssl_generative}$$

Parameters $\psi,\pi$ of $p(x|y)$ and $p(y)$ are learned from labelled and unlabelled data, e.g. by the EM algorithm, and predictions $p(y|x) \!=\! p(x|y)p(y)/p(x)$ follow by Bayes’ rule. Figure \[fig:graph\_models\]  shows the corresponding graphical model. Whilst generative SSL has an appealing probabilistic rationale, it is rarely used in practice, similarly to its counterpart for fully supervised learning, in large part because $p(x)$ is often complex yet mustover predictions for labelled data provides an empirical approximation to $p(\theta)$; and under certain assumptions (considered in Sec. \[sec:scenarios\]), the analytical form of $p(\theta)$ can be derived *a priori*. To formalise, we define: $\smash{\theta^{\mX^l\!} \!=\! \{\theta^{x}\}_{x\in\mX^l}}$ as the set of parameters of $p(y|x)$ for each $x \!\in\! \mX^l$ ($\smash{\theta^{\mX^u\!}}$ defined similarly); and $\alpha$ as parameters of the marginal distribution over $\theta$. For example, in $K$-class classification $p(y|x)$ is a categorical distribution with parameter vector $\theta$ on the simplex $\smash{\Delta^K}\!\subseteq\!\sR^K$, with $\smash{\theta^{x}_k \!=\! p(y \!=\!k|x)}, k \!\in\!
\{1\, ...\, K\}$; and $\alpha$ defines a distribution over $\Delta^K\!$. Treating $\theta$ and $\alpha$ as latent random variables, the conditional distribution of the data factorises comparably to Eq. \[eq:no\_use\]: $$\begin{aligned}
    \label{eq:SSL_new}
    p( \mY^l| \mX^l\!, \mX^u)


our last concert, they wouldn't let me say anything to the audience!" "Who the heck did that?" "Chief Go, saying that if fans hear my voice, they will be completely put off." "That stupid Chief Go needs to learn a lesson." "What's wrong with our Bit Na's voice?" "It's unique and sexy!" "I don't know!" "Bit Na, you wanted a new car, right?" "Why?" "I'll buy you one." "A nice one." "Are you serious?" "I've got a big payment coming in." "Then I'll buy you one." "Oppa..." "I la la, I love you!" "I suppose all your experience counts for something, seeing that you managed to bring in Kang Hyun Min when the Empire failed to do that." "You know, once I target an actor, I never letKang Hyun Min, and changed the writer." "Why can't you issue us a certificate when you've already given us the slot?" "Who says I'm not issuing you one?" "Bring me the bank statement that has the funds for this production." "What?" "Not something you just type up on Word, but an actual bank book that shows the money." "Director..." "You know it, too." "How many drama productions bite off more than they can chew, and end up in a wreck with insufficient funds." "That hurts the reputation of the broadcasting station as well!" "Once you give me the certificate, I get the investment from Japan." "Not just a couple billion, but 10 billion!" "Well then, show me the bank book with that 10 billion." "Director ..." "A certificate


" Here, another bottle." " Thanks." " Aunty, we'd like another grilled mackerel." " Yes." "Yes, coming!" "Hey, what are you doing here?" "Because they liked my script so much, I'm on vacation." "For a week." "Well then, hurry up and grill some mackerels." "Can't you see how busy we are?" "Yes, Madame Kang .(Madame Tenacity)" "The money?" "It will be withdrawn from the bank in 30 minutes." "Ohhyung Golf Course in Nonhyun-dong." "Director Moon's locker number and combination." "8911?" "8911..." "No, put it in your mouth and swallow it." "What?" "We can't leave any trace behind unless they cut our guts open." "Get the money and deliver it right away." "I'll go get the certificate of broadcasting slot." "Yes, I got it." "Where did they all gonice, asking me to help you, right?" "asking me to help you, right?" "No, I'm not like that." "It's no use." "Come to think of it, I was a bit nervous about the writer being a rookie." "This is for the best." "Don't get your heart broken over this." "It's the nature of this field." "That's not it!" "What the heck?" "I put my everything at stake for my "The Morning of Kyeongseong."" "Though I'm leaving, I want you all to take it seriously with affection." "Is that so hard, you idiots?" "!" "Is she crazy?" "What are you doing?" "Drag her out of here." "Yes." "Leave." "You morons!" " You're so drunk." " It's mine!" " What's yours?" " Just go!" " Let go of me!" "You


protective antibodies for all dengue virus serotypes by a recombinant protein, and potentially offers advantages over the tetravalent mixture of four domain III fragments.

Material and Methods
====================

Cells and viruses
-----------------

Four serotypes of the dengue virus, (DENV 1 strain 16007, DENV2 strain Th-NH-81/93, DENV3 strain BR/D3LIMHO/ 2006, DENV4 strain PH/BID-V3361/1956), were used for this study. Virus propagation and titration was performed in Vero B4 cells. All obtained from Bernhard Nocht Institute for Tropical Medicine (BNITM, Germany). Cells were maintained in Dulbecco\'s Modified Eagle\'s Medium (DMEM) with 4.5 g/l glucose \[were obtained from PAA Laboratories, Colbe, Germany\] supplemented with 10 % (v/v) heat inactivated fetal calf serum (FCS) \[PAA\], 2 mM glutamate \[PAA\], 50 U/ml penicillin and 50 µg/ml streptomycin \[Gibco\] in a 5 % CO~2~ humidified incubator, at 37 °C.

Designing andthe blocking step was carried out by using 5 % skimmed milk in PBS for 1 h at 37 ºC. Mouse serum samples were serially diluted (100 μl/well) in blocking buffer (1:100 to 1:12800, and incubated for 2 h at 37 ºC. After washing, bounded IgG was detected with horseradish peroxidase-conjugated rabbit anti-mouse IgG Fc (Abcam, UK), diluted 1:4000 in blocking buffer. Finally, 100 μl of 3,3\',5,5\'-tetramethylbenzidine (TMB) as chromogenic substrate were added and the plates were incubated at RT for 15 min. The reaction was stopped by adding 100 μl of 2N sulfuric acid and the absorbance at 450 nm was performed by using ELISA reader (Bio-Rad).

Focus reduction neutralization tests (FRNT)
-------------------------------------------

Anti-dengue neutralizing antibodies were detected by using a focus reduction neutralization test (FRNT), as reported previously (Leng


shown in Table 2[(Tab. 2)](#T2){ref-type="fig"}, anti-ED3F serum reduced the number of FFU when was pre-incubated with virus. These results indicate that tetravalent ED3F protein is able to elicit cross-neutralizing antibodies to block all four serotypes of dengue virus. While, all of the monovalent antiserum samples (sera G1-G4) showed cross-neutralizing effects, serotype specific neutralization was observed only in high diluted sera (1:80 and 1:40). Interestingly, in a very similar way with anti-ED3F serum, the serum from immunized mice with tetravalent formulation of four ED3 proteins (G5) cross-neutralized all four serotypes of dengue virus. Complete neutralization of dengue viruses by all anti-ED3 sera was observed up to a dilution of around 1:40. These data revealed the potential of recombinant envelope protein domain III in developing neutralizing immune responses against dengueupward. Though, there is significance in cell proliferation between different time points (24 h and 72 h). In comparing with mock immunized group (G7), it can be concluded that the cell proliferation is higher in dengue vaccine immunized mice. Furthermore, quantitative ELISAs were used to detect the secreted IFN-γ and IL-4 cytokines from splenocytes of the immunized mice re-stimulated with the corresponding antigens (Figure 4[(Fig. 4)](#F4){ref-type="fig"}). Splenocytes of unimmunized mice stimulated by ConA were included in cytokine assay as a positive control group (G8). In comparison with the negative control group (G7), the concentration of two measured cytokines increased markedly in all ED3-immunized groups. However, in both MTT and cytokine assays no significant differences between the immunized groups were detected. It is likely due to application of high


previously (Fahimi et al., 2014\[[@R12]\]). However, this study was aimed to design a tetravalent vaccine candidate in the form of a physical mixture of four ED3 fragments or in a single chimeric protein. One approach that has been suggested to minimize the possibility of antibody-dependent enhancement of infection, occurring after vaccination, is to design a tetravalent subunit vaccine containing potent neutralizing epitopes against all four serotypes. In the current study, a tetravalent ED3-based recombinant antigen (ED3F) was designed and expressed. To facilitate easy purification, ED3F protein and four ED3 proteins with a C-terminal 6x-HisTag were expressed in soluble form and without any bulky fusion partner like MBP or GST. Immunogenicity of this tetravalent fusion protein was verified and also compared with tetravalent formulation of ED3s. The reactivity ofafter the second purification step. Lane 7 and 8, ED3-F tested for immune reactivity against anti-dengue monoclonal antibodies (lane 6) an anti-His~6~-Tag antibody (lane 7) by Western blot. Lanes 1, 4 and 6 protein molecular weight markers](EXCLI-17-1054-g-001){#F1}

![Antibody titers to ED3 in pooled sera from immunized mice. Sera collected from BALB/c mice (n=6) that had been immunized subcutaneously with the recombinant ED3 antigens were pooled for each group and the pooled sera were tested at various dilutions for their reactivity to ED3 antigens by ELISA. The mock-immunized mice serum pool G7 was used as a control. (A) The four ED3 proteins ED3-1, ED3-2, ED3-3 and ED3-4 were coated onto ELISA plate as individual antigens or as a mixture in order to determine anti-ED3 antibody titers in the pooled sera


have been described in bacteria: one begins with a dehydrogenation step, followed by phosphorylation, and the other begins with a phosphorylation reaction, followed by dehydrogenation ([@B28], [@B29]). In either case, the terminal metabolic currency is dihydroxyacetone-P. In the soil bacterium *P. putida* KT2440, the second pathway is the prevalent (and likely the only) glycerol dissimilatory process ([Fig. 1](#fig1){ref-type="fig"}). Uptake of the compound is mediated by the GlpF facilitator, which fosters a diffusion reaction ([@B30]). Once inside the cell, glycerol is phosphorylated by an ATP-dependent glycerol kinase (GlpK) to *sn*-glycerol-3-P (G3P), which cannot diffuse out of the cell. G3P is the substrate for GlpD, a membrane-bound G3P dehydrogenase that yields dihydroxyacetone-P ([Fig. 1A](#fig1){ref-type="fig"}). Some microorganisms, such as *Escherichia coli* and *P. aeruginosa*, are able to internalize and utilize G3P or dihydroxyacetone ([@B28]), intermediatesμ~max~ values, all individual samples reached more or less the same maximal OD~600~ values (in the case of glycerol cultures, ca. 0.5 to 0.6 units).

![(A) Growth of *P. putida* KT2440 in single-cell batch cultures. Multiwell microtiter plates were inoculated with a highly diluted preculture previously developed in LB medium in order to start each culture from 1 cell per well. Cells were grown at 30°C in 200 µl of M9 minimal medium containing 40 mM glycerol with rotary agitation. The time needed to reach an optical density measured at 600 nm (OD~600~) of 0.3 (mid-exponential phase of growth) is indicated by a red arrowhead for 50 independent cultures to illustrate the delay in growth initiation among individual wells. This parameter, termed time of metabolic response (*t*~MR~), was further used to quantify the response


the bistable phenotype of *P. putida* KT2440 on glycerol. When the analysis of single-cell batch cultures in microtiter plates was performed with these recombinant cells, the two subpopulations previously seen for the wild-type strain were not observed (data not shown). These results are in line with the notion that if cells are pregrown on glycerol (ensuring a sufficiently high G3P supply), the stochastic growth phenomenon is no longer observed.

Conclusion. {#s1.8}
-----------

Phenotypic variation within an otherwise genetically clonal population endows bacterial populations with functionalities that, under given particular circumstances, protect the genetic pool of the group under adverse conditions. The essence of the phenomenon is that either a genetic or a metabolic device generates differential expression of a certain trait, whether structural (e.g., phase variation of pathogens \[[@B50]\]), biochemical, or physiological.the plasmids used in this study are listed in [Table 1](#tab1){ref-type="table"}. *P. putida* and *E. coli* were routinely cultured in 250-ml Erlenmeyer flasks containing 50 ml of the corresponding culture medium with agitation at 170 rpm at either 30°C (*P. putida* strains) or 37°C (*E. coli* strains). For the propagation and construction of vectors, *E. coli* CC118 λ*pir* was cultured in LB medium ([@B70]) containing the appropriate antibiotics. Physiological experiments were carried out in M9 minimal medium ([@B70], [@B71]), containing 6 g ⋅ liter^−1^ Na~2~HPO~4~, 3 g ⋅ liter^−1^ KH~2~PO~4~, 1.4 g ⋅ liter^−1^ (NH~4~)~2~SO~4~, 0.5 g ⋅ liter^−1^ NaCl, 0.2 g ⋅ liter^−1^ MgSO~4~⋅7H~2~O, and 2.5 ml ⋅ liter^−1^ of a trace element solution ([@B72]). Either 40 mM glycerol, 20 mM glucose, or 30 mM sodium succinate was added to M9 minimal medium as filter-sterilized solutions as the sole carbon source (i.e., the final medium contained 120 mM carbon atoms in all the experiments). Solid medium


binds CD58 (LFA-3), another adhesion molecule broadly expressed on both hematopoietic and non-hematopoietic cells \[[@B43-cells-09-00753]\]. CD2 engagement by LFA-3 is involved in NK cell activation \[[@B7-cells-09-00753]\], suggesting that it may function as co-receptor during natural cytotoxicity.

Even if, as already mentioned, LFA-1 engagement mediates NK cell granule polarization \[[@B27-cells-09-00753],[@B34-cells-09-00753],[@B35-cells-09-00753],[@B36-cells-09-00753]\], it has been also shown to inhibit NK cell functions inducing both lower percentages of degranulating NK cells \[[@B27-cells-09-00753],[@B35-cells-09-00753],[@B36-cells-09-00753]\] and apoptosis of activated NK cells. For these reasons, LFA-1 engagement has been also proposed as a negative feedback regulatory mechanism to keep NK cell cytotoxic function under control \[[@B44-cells-09-00753]\].

On account of what was previously said, it is clear that target cell recognition by NK cells in both (patho)physiological and immunotherapeutic conditions is a highly dynamic process controlled by integrated signalsCD56^dim^ NK cells and combinations of anti-NKp46 with coactivating mAbs induced an increase of degranulating NK cells in both CD56^dim^CD16^bright^ and CD56^bright^CD16^dim/neg^ subsets ([Figure 3](#cells-09-00753-f003){ref-type="fig"} and [Figures S2 and S3](#app1-cells-09-00753){ref-type="app"}). Of note, a synergistic response of anti-NKp46 mAb in combination with anti-2B4 was confirmed in CD56^dim^CD16^bright^ NK cells ([Figure 3](#cells-09-00753-f003){ref-type="fig"} and [Figures S2 and S3](#app1-cells-09-00753){ref-type="app"}), but not in CD56^bright^ ones (both CD16^neg^ and CD16^dim^, [Figure 3](#cells-09-00753-f003){ref-type="fig"} and see [Figures S2, S3 and S5](#app1-cells-09-00753){ref-type="app"}). Combination of anti-NKp46 with anti-2B4 induced about threefold increase in the number of CD56^dim^ degranulating cells respect to anti-NKp46 alone (NKp46 vs. NKp46+2B4, *p* \< 0.05) and the CD107a MFI of CD56^dim^ degranulating NK cells incremented of about 20% respect to NKp46 alone ([Figure 3](#cells-09-00753-f003){ref-type="fig"}A,B). Differently, coactivation with anti-DNAM-1 or anti-CD2 did not induce statistically


not significantly different from NK cells cultured without cytokine stimulation ([Figure 5](#cells-09-00753-f005){ref-type="fig"}A).

Indeed, along with days of culture, surviving NK cells showed a progressive increase in their degranulation response which was relatively independent on cytokine stimulation (see [Figure S5](#app1-cells-09-00753){ref-type="app"}, as an example). As a matter of fact, NK cells cultured for three days with or without IL-2 and stimulated with anti-NKp46 showed degranulation percentages which were more than fourfold higher than those of resting NK cells ([Figure 5](#cells-09-00753-f005){ref-type="fig"}A and [Figure 1](#cells-09-00753-f001){ref-type="fig"}). After NK cell activation with cytokines, no statistically significant degranulation differences were detectable in the various NK cell subsets (CD56^bright^ and CD56^dim^ or licensed and unlicensed CD56^dim^ NK cells) for the mAb combinations tested ([Figure 5](#cells-09-00753-f005){ref-type="fig"}B,C). Moreover, PBMCs stimulated with anti-NKp46 plus anti-2B4 produced a diffuse CD107a labellingreceptor with its ligand CD48 \[[@B87-cells-09-00753]\]. Indeed, 2B4-CD48 *cis*-interaction has been shown to modulate 2B4 cell surface expression, baseline phosphorylation and cytotoxicity induced after contact with susceptible target cells, suggesting a general role for *cis* interactions in modulating the threshold for receptor engagement in *trans* and the regulation of receptor function \[[@B87-cells-09-00753]\]. *Cis* interactions can increase or decrease the threshold of NK cell activation depending on receptor type. As already mentioned, it facilitates NK cell activation, as the number of inhibitory receptors available to interact in *trans* is reduced (e.g., mouse Ly49 receptors); by contrast, 2B4-CD48 *cis* interaction dampens NK-cell activation. Interestingly, the acquisition of activation receptor ligand by trogocytosis has been described to dampen NK cell response \[[@B90-cells-09-00753]\], suggesting that *cis* association of activating receptor (Ly49H) with


interaction with LFA-1 on leukocytes. Because ICAM function is regulated primarily by its surface expression level, *cis* interaction could both modulate ICAM surface expression and dual (activating or inhibiting) functions of LFA-1 receptor. Finally, *cis* interactions mediated by intracellular or surface "adaptors" might explain human NK cell licensing mechanism mediated by self-KIR and NKG2A molecules, as functionally analogous mouse Ly49 molecules.

5. Conclusions {#sec5-cells-09-00753}
==============

The possibility to expand and activate NK cells is a crucial aspect to benefit of NK cell functions in immunotherapeutic approaches. Indeed, ex-vivo activated NK cells can be exploited to counter cancer cells after their injection; however, we have only limited knowledge regarding the activating and inhibitory signals induced in the different NK cell subsets. In the present work, we have identified synergistic and antagonistic activationthe League Table (measuring qualitative results) and… Near bottom of my Composite Index (measuring quantitative results). If you’re a Chicago Fire supporter be prepared for some pretty harsh numbers as additional analysis gets offered below…

Working from the back – forward – Defending first…

Here’s the Defending Possession with Purpose (DPWP) Index for starters:

First things first:

Chicago are the worst in team performance when it comes to overall defending – in other words the combined results of their opponents in Possession, Passing Accuracy, Penetration, along with creation of Shots Taken, Shots on Goal and Goals Scored is last; this Index does not measure Points garnered in the League Table.

In terms of racking and stacking the Six Steps measured, one by one, Chicago yield the third highest amount of Possession, to their


faction is accused by all other three as the most revisionist one. This faction is trying to understand the problems of 20th century socialism from critical perspectives. this faction believes that socialism needs to be re-articulated given the experiences, both positive and negative, of the socialist experiments in the last century. It has published many books including "Globalisation Of Capital".

The fourth faction and is among the most organized factions, is the Re-organizing Committee, Communist League of India (Marxist-Leninist). It regularly publishes a party-organ called "Lal Salaam" every six months and maintains a web-site www.cli-ml.com.  This faction is mainly engaged in organizing industrial workers in North India.

External links
Communist League of India (Marxist-Leninist)

.

Category:Defunct communist parties in India
Category:Political parties established in 1978
Category:1978 establishments in India
Category:Political parties with year of disestablishment---
address:
- |
     Physics Department, University of Warwick, UK.\
    [E-mail: p.f.harrison@warwick.ac.uk]{}
- |
    Centre for Fundamental Physics (CFFP), and Particle Physics Department (PPD),\
    CCLRC Rutherford Appleton Laboratory, Chilton, Didcot, OX11-0QX, UK\
    [E-mail: w.g.scott@rl.ac.uk]{}
author:
- 'P. F. HARRISON'
- 'W. G. SCOTT'
title: ' STATUS OF TRI/BI-MAXIMAL NEUTRINO MIXING [^1]'
---

RAL-TR-2004-004\
hep-ph/0402006\
31 Jan 2004

and

Tri/Bi-Maximal Mixing
=====================

Tri/bi-maximal mixing (TBM) is a specific lepton mixing ansatz, which is now already five years old in the literature [@tbm]: $$\begin{aligned}
     \matrix{  \hspace{0.4cm} \nu_1 \hspace{0.3cm}
               & \hspace{0.2cm} \nu_2 \hspace{0.3cm}
               & \hspace{0.2cm} \nu_3  \hspace{0.4cm}


\right)
\label{tb0}\end{aligned}$$ In TBM (Eq. \[tb0\]) the intermediate mass neutrino $\nu_2$ is [*tri*]{}-maximally mixed between all three lepton flavours, as in the original trimaximal scheme [@tri], while the heavy neutrino $\nu_3$ is [*bi*]{}-maximally mixed between mu and tau flavours, as in the original bimaximal scheme [@bim] (where we take a conventional mass-hierarchy for simplicity). TBM may also be viewed as a special case of the Altarelli-Feruglio mixing scheme [@alf].

Of course we recognise that TBM (Eq. \[tb0\]) is unlikely to be realised [*exactly*]{} in nature [@syms]. In particular, the absence of $CP$-violation predicted in exact TBM would be surprising, given the success of the Standard Model explanation of $CP$-violation in the case of the quarks. We see Eq. \[tb0\] as a useful summary of the trends in the current experimental data, suggestive of possibleSun, giving $P(e \rightarrow e) = 1/3$ there. These predictions remain valid in tri/bi-maximal mixing, because the solar neutrino remains trimaximally mixed in that case.

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A. J. Baltz, A. S. Goldhaber and M. Goldhaber, Phys. Rev. Lett. 81 (1998) 5730, hep-ph/9806540. D. V. Ahluwalla, Mod. Phys. Lett. A 18 (1998) 2249.\
H. Giorgi and


S. L. Glashow, Phys. Rev. D 61 (2000) 097301, hep-ph/9808293. G. Altarelli and F. Feruglio, Phys. Lett. B 439 (1998) 112, hep-ph/9807353; Phys. Lett. B 451 (1999) 388, hep-ph/9912475. P. F. Harrison and W. G. Scott, Phys. Lett. B 535 (2002) 163, hep-ph/0203209. P. F. Harrison and W. G. Scott, Phys. Lett. B 333 (1994) 471, hep-ph/9406351. Y. Fukuda et al.  Phys. Rev,. Lett.  81 (1998) 1562, hep-ex/9807003.\
M. Sanchez et al.Phys. Rev. D 68 (2003) 113004, hep-ex/0307069. M. H. Ahn et al.Phys. Rev. Lett. 90 (2003) 041801, hep-ex/0212007. M. Apollonio et al.Eur. Phys. J. c27 (2003) 331, hep-ex/0301017;\
Phys. Lett. B 466 (1999) 415, hep-ex/9907037;\
Phys. Lett. B 420 (1998) 397, hep-ex/9711002 F. Boehme et al.Phys. Rev. D 64 (2001) 112007, hep-ex/0107009;\
Phys. Rev. Lett. 84 (2000) 3764, hep-ex/9912010;\
Phys. Rev. D 62 (2000) 072002, hep-ex/0003022. G. L. Fogli, E. Lisi and A. Marrone, hep-ph/0308055. Q. R. Ahmad et al.  Phys. Rev. Lett. 89 (2002) 011301, hep-ex/0204008. S. N. Ahmed et al.  Submitted to Phys. Rev. Lett. hep-ex/0309004. J. N. Bahcall, M. H. Pinsonneault and S. Basu,\
AstroPhys. J. 555 (2001) 990, astro-ph/0010346.

J. Abdurashitov et al.  J. Exp. Theor. Phys. 95 (2002) 181, astro-ph/0204245. J. W. Hampel et al. Phys. Lett. B447 (1999) 127.\
M. Altman et al. Phys. Lett.Q:

Looks like a query string, but won't act as a query string

I am working with VB in asp.net,
The basic problem is, I want to pair up the elements in a string, exactly like request.QueryString() will do to the elements in the query string of the web page.
However instead of the function looking at the current webpage query string I want it to look at a string (that is in the exact form of a query string) stored as a variable.
So if I define a string such as:
Dim LooksLikeAQueryString As String = "?category1=answer1&category2=answer2"

I want a function that if I input LooksLikeAQueryString and "category1" it outputs "answer1" etc.
Is there anything that can already do this or do I have to build my own function? If I have to


Sgt. 1st Class William “Kelly” Lacey, 38, of Niceville was killed Jan. 4 while defending his outpost from an insurgent attack in Afghanistan.
His stepmother, Karla Lacey, and brother, Shawn Lacey, accepted two plaques commemorating Lacey on behalf of his wife, Ashley, and his father, John.
“We all pray that there will be no more names and portraits added,” said Meredith McQuagge, commander of the Military Order of the Purple Heart Chapter 811.the other questions seem to have tried to address the all objects part of the question.
I'm amazed you have to roll your own with this - I expected there to be a drop schema blah cascade.  Surely every single person who sets up a dev server will have to do this and having to do some meta-programming before being able to do normal programming is seriously horrible.  Anyway... rant over!
I started looking at some of these articles as a way to do it by clearing out a schema: There's an old article about doing this, however the tables mentioned on there are now marked as deprecated.  I've also looked at the documentation for the new tables to help understand what is going on here.
There's another


'use strict';

module.exports = function (t, a) {
	a(t.call(new Date(2001, 0, 1)), 31, "January");
	a(t.call(new Date(2001, 1, 1)), 28, "February");
	a(t.call(new Date(2000, 1, 1)), 29, "February (leap)");
	a(t.call(new Date(2001, 2, 1)), 31, "March");
	a(t.call(new Date(2001, 3, 1)), 30, "April");
	a(t.call(new Date(2001, 4, 1)), 31, "May");
	a(t.call(new Date(2001, 5, 1)), 30, "June");
	a(t.call(new Date(2001, 6, 1)), 31, "July");
	a(t.call(new Date(2001, 7, 1)), 31, "August");
	a(t.call(new Date(2001, 8, 1)), 30, "September");
	a(t.call(new Date(2001, 9, 1)), 31, "October");
	a(t.call(new Date(2001, 10, 1)), 30, "November");
	a(t.call(new Date(2001, 11, 1)), 31, "December");
};
Over the years, Congress has earned monikers ranging from the world's greatest deliberative body, to a bunch of children. Last week it was hard to argue with the second one. A profile in The National Journal says the first day of Congress resembles the first day of school. Freshmen lawmakers get the same jitters.

The General Services Administration has a confession: The industrial funding fee added to orders through its signature Multiple Awards Schedule program pays for a little something extra. Now GSA wants to make sure federal buyers know where its money is going.

It seems like only yesterday the Defense Department was stepping gingerly into the world of Windows 3.1. Flag officers used Minesweeper to learn how to use a mouse. Fast forward 20 years and now we're


to keep pace. Like every disruptive scenario assessed through this recent Blog series, there are massive implications that drive the need to analyze the scenario and formulate a set of responses.

The Maker Economy is one of several disruptive scenarios in our line of sight. An additional challenge becomes very apparent when you look across this growing set of disruptive scenarios – they impact each other. This will force companies to view relevant disruptive scenarios holistically, while effectively connecting the dots between scenarios. For example, the Smart City scenario intersects with the maker movement to create a differentiated environment that attracts talent.

So what are the Maker Economy implications and possible responses? A recent report published by Deloitte captures the Impact of the Maker Movement across several industries, and presentsNance Jr. has logged. Veteran Brandon Bass is steady, but he can't stretch the floor the way World Peace can.

As Synergy Sports Technology observed, World Peace shot it well during his brief run in Italy:

And, as Sporting News' Adi Joseph quipped, it wasn't that long ago that World Peace gave the Lakers good minutes:

That Lakers squad went 45-37, and it never played better than when World Peace was on the floor. With him, L.A. outscored opponents by 4.9 points per 100 possessions. Without him, the Lakers were outscored by 3.2 points per 100 possessions.

No one on that team had a higher on-off split. And, for a refresher, that roster featured Bryant, Dwight Howard, Pau Gasol, Steve Nash and Antawn Jamison, among others.

Days can feel like decades in today's


Tony Gonzalez tells agent to start negotiating

Tony Gonzalez hasn't publicly declared that he will return for a 17th NFL season, but here's another sign that he apparently is leaning in that direction: The Atlanta Falcons tight end has given his agent, Tom Condon, the green light to talk to the team about a new contract, a person with knowledge of the negotiations told USA TODAY Sports.

Fantasy Impact:

It looks as if Gonzalez is going to return for another season provided he the Falcons agree to let him miss a portion of training camp. He finished #3 in fantasy PPG in 2012 and #6 in 2011 so another top 5 season is well within reach.at a big discount at Sally Beauty Supply.

Here is the full plate image from the Pueen Palte 57. There are so many ways you could wear this, I just love it. I think I will have to do a Yellow Brick Road mani verrrrry soon! Happy Monday!


extra layer of immediacy. But it’s most to be cherished for bringing us a rounded portrait of a woman whose life was deeply engaged with her work, and whose work illuminated many aspects of her life.

Had I expanded my selection to include theater books not exclusively related to Broadway or Broadway figures, I might have included any number of other choices, from Kenneth Tynan’s fiery “Curtains,” or for that matter the revealing volume of his diaries that were edited by John Lahr. The seminal theater director Peter Brook has written insightful books about his inquisitive approach to creating theater, beginning with “The Empty Space.” And new theater books keep coming: Hal Holbrook and John Lithgow have just published autobiographies, and I’m interested in reading the new volume ofSpalding Gray’s diaries that has just hit the stores.

Then again, as I turn from the computer to the vista of my living room, which is largely furnished with books – books on traditional shelves, books on those trendy upright tower shelves, books simply stacked up on the floor in neatly arranged piles that I desperately hope appear decorative – I realize that I am in danger of becoming an honorary Collyer brother and should probably begin the process of divestment. (Oops: three new Thirkells just arrived from Amazon.) Perhaps it’s time to make that Kindle leap?

Still I’d be curious to hear if you have any old or new favorite books about theater that might have escaped my attention, even if their acquisition might make it impossible for me


years old who receive the operation within 6 months of injury (Nagona, 1998).

Spinal accessory nerve (SAN) {#sec2-3}
----------------------------

Classified as an extra-plexal nerve, SANs are rarely injured in patients who have brachial plexus injury (Samardzić et al., 2000). When they were first used in 1972, SANs produced satisfactory outcomes. Since then, SANs have been transferred to suprascapular and musculocutaneous nerves to restore shoulder abduction and elbow flexion, respectively. Brunelli and Brunelli (1991) showed that SAN transfer to the suprascapular nerves was the best solution because the supraspinatus and infraspinatus muscles are supplied by similar nerves. In 1987, Gu proved that the efficacy of directly suturing SANs to suprascapular nerves was higher than that of using a nerve graft. Nerve transfers involve the donor nerve being brought closer to the endorgan. The closer the transfer is to the target muscle, the shorter the distance the regenerating axons have to travel and the better the functional re-innervation (Addas and Midha, 2009).

Traditionally, accessory to suprascapular nerve transfer has been accomplished through an anterior supraclavicular approach. However, there are some disadvantages of this method, such as scarring, nerve retraction or displacement, and nerve tumor. Each of these complications may cause difficulties when searching for the suprascapular and accessory nerves. Consequently, clinicians have started to use a posterior approach, particularly when transfer of the triceps branch of the axillary nerve is considered in combination to accessory nerve transfer (Rui et al., 2013). Colbert and Mackinnon (2006) used the posterior approach, and achieved better protection to the nerves supplying the trapezius as well


well-vascularized bed.

In recent years, the thoracoscope has been widely used in cutting out the phrenic nerve. In 1999, Gu and Shi (1999) first carried out a study of this procedure. Preliminary results showed that this method was used to transfer the phrenic nerve to the ulnar nerve, successfully restoring thumb flexion in 20 patients. Compared with traditional methods used in cutting out the phrenic nerve, the length of the excised nerve can be increased by using a thoracoscope. In 2002, Xu et al. (2002) successfully cut out the full length of the phrenic nerve with the aid of a thoracoscope and transferred it to the musculocutaneous nerve. This method reduced the recovery time for elbow flexion to an average of just 5 months.

The greatest concern in phrenic nerveGallery in Overton Park, and the McKeller Lake Boat Dock.  In June, 1961, the Park Commission's plan, which was approved by the court in the instant case, proposed to desegregate Fairgrounds Amusement Park at the end of 1961.  This park, at the time of the hearing of this appeal, had already been desegregated.  The Park Commission's plan also proposed, beginning in January 1962, to desegregated all 7 public golf courses on a three-year schedule.  Four golf courses had already been desegregated at the time of the hearing of this appeal.

7
From the testimony of the Director of Parks of the City of Memphis, it appeared that, as each park and facility was desegregated, more recreational directors and supervisors were necessary and were appointed, and more


facilities should be integrated.  In addition to the avoidance of confusion and violence, the city officials also took into consideration the effect of immediate or gradual desegregation upon the question of revenue from concessions operated by others for the Commission, and by the Commission itself.

13
The concessions, for certain amusement devices, operated by individuals, are granted by the Commission for rentals based upon gross receipts.  The Commission felt that if it were to desegregate the Fairgrounds Amusement Park in the middle of the year, it would be unfair to such concessionaires and detrimental to the Commission.  This amusement park was, however, to be desegregated six months after the hearing in the district court, or on January 1, 1962, and it has been desegregated since that date.with the park officials, the police officers, and his knowledge of the City and its people.

14
None of the evidence introduced on behalf of the City of Memphis is questioned.  Whether the system of organized play in which these thousands of children take part, may be greatly curtailed or put in jeopardy by immediate desegregation of all the parks and playgrounds, is deemed irrelevant by appellants.  The probable closing down of many of these facilities is considered equally irrelevant by appellants, as are any questions of orderly transition, police protection, maintenance of the present friendly and peaceful relations between all of the white and colored citizens of Memphis.

15
The evidence before us shows that what the City of Memphis proposes is not a mere promise to do something,


proposed to accelerate this program where judged practicable.

18
The foregoing was the plan which the district court approved; the court also directed that the City should file a further plan for the integration of all of the parks, playgrounds, and recreational facilities within a period of six months from the date of its judgment; and the court expressly retained jurisdiction of the case for such further proceedings as might be necessary from time to time.

19
Appellants made no specified objections to the plan which the district court approved.  As the court stated in its opinion:

20
'No valid objection to this plan in the Court's opinion is offered in this case.  The plaintiffs merely say they want all of these facilities fully integrated now.  Nothing else seems to matter.'

21
ThisQ:

Looking for help coding a Lowest Common Multiple function without a GCF function in python

I figured out how to do it with the use of a gcf function. However, I need to create an LCM function with two parameters, "x" and "y" with the use of recursion. This is what I have so far:
def lcm(x, y, counter=1):
    if (counter%x == 0 and counter%y == 0):
        return counter
    return lcm(x, y, counter+1)

I'm wondering if I could create a similar function without the use of the third parameter, "counter".
Thanks.

A:

You can check that hte following does the trick
def lcm(x, y):
    if y > x:
        x, y = y,


Q:

MDX: How to make a WHERE when a member from the same Hierarchy already is in rows or cols?

I have a dimension called Date, with one hierarchy in it (default).
From that I want Months on rows and filter on Year = 2014.
This doesn't work:
SELECT
  [Date].[Month].Members ON 0,
  Measures.Amount ON 1
FROM [GL]
WHERE [Date].[Year].[2014]

I have tried with FILTER, and tuples also but nothing works. In SSAS (Im using Mondrian) I would use a Sub Query but there is no support for that in Mondrian.
Does anyone know how to accomplish this?

A:

Try the DESCENDANTSfunction:
SELECT
  DESCENDANTS(
    [Date].[Year].[2014] //<<this should be a member
    ,[Date].[Month]      //this should be a level name
  ) ON 0,
  Measures.Amount ON 1
FROMis in ERISA a so-called "preemption" clause and a so-called "savings" clause. The preemption clause, 29 U.S.C. § 1144(a), preempts any state law claim that "relates to employee benefit plans." Pilot Life Ins. Co. v. Dedeaux, 481 U.S. 41, 107 S.Ct. 1549, 1552, 95 L.Ed.2d 39 (1987). According to the Supreme Court in Dedeaux, the savings clause, 29 U.S.C. § 1144(b)(2)(A), excepts from this preemption "laws that regulate insurance." Dedeaux, 481 U.S. at 45; 107 S.Ct. at 1552 (emphasis supplied). If the Eleventh Circuit correctly interpreted Dedeaux in Anschultz v. Connecticut General Life Ins. Co., 850 F.2d 1467 (11th Cir. 1988), Alabama Code § 27-12-6 would not meet the criteria for an exception from *807 ERISA preemption, especially since this particular Alabama statute does not purport to transfer


to two very fine, traditional American specialties called ‘spaghetti with meatballs,’ and ‘cotoletta parmigiana,’” which he thought were “just for fun called Italian,” but added “as a matter of fact, I found them both extremely satisfying and I think someone in Italy should invent them for Italians over there.”

So there you go, spaghetti and meatballs may not be Italian, but it is a symbol of Italian-American cuisine and as The Lady and the Tramp may tell you, as American as Walt Disney himself:Q:

Who is Govindaraja and how is he related to Venkateshwara?

Tirupati is most commonly associated with the world-renowned Tirumala Venkateshwara Temple.  But there is another Vishnu temple in Tirupati, the Govindaraja Swami Temple.  (This isn't the only Govindaraja temple; there's also one in Chidambaram.)  As I understand it, the story of the temple goes roughly as follows: when Venkateshwara (the Vishnu deity in Tirupati, AKA Srinivasa or Balaji) wanted to marry Padmavathi, he got a large loan from Kubera (the god of wealth) to pay for the wedding expenses.  Afterwards, Govindaraja, an elder brother of Venkateshwara and another form of Vishnu, helped Venkateshwara by counting the money.  He spent a long time weighing the gold on a giant scale until he fell asleep on


//   1) retrieve its properties
    double myvar1 = sqlite3_colum_double(statement,6)
    double myvar2 = sqlite3_colum_double(statement,7)
    ....
    double myvar25 = sqlite3_colum_double(statement,25)
    //   2) create the object and add it to a vector for the interpolation
}
sqlite3_reset(statement);
sqlite3_clear_bindings(statement);

The database is opened with
sqlite3_open_v2(path,&db,SQLITE_OPEN_READONLY,NULL)
Problem
It takes about 2.5 seconds to make 16 queries and extract 1024 points. Sqlite3 operations take 99.8% of the computing effort (callgrind)...
What am I doing wrong ?
I have tried EXPLAIN QUERY PLAN SELECT * FROM myTable WHERE (v1=0 AND v2=0 AND v3 BETWEEN 0 AND 3 AND v4 BETWEEN 0 AND 3 AND v5 BETWEEN 0 AND 3.
The result is SEARCH TABLE myTable USING INDEX idx (v1=? AND v2=? AND v3>? AND v3<?)
WillAssociations between caregiving and health outcomes among parents of children with mental illness: an attachment perspective.
This study examines the associations between attachment, caregiving, and health outcomes (perceptions of somatic and depressive symptoms) in a sample of 194 parents who have a child with mental illness. Securely attached parents reported using more comforting behavior and tactile communication with their children with mental illness. Parents with a fearful attachment reported using more overinvolved and egocentric caregiving, as well as less tactile communication, and these caregiving behaviors partially mediated a positive association between fearful attachment and both somatic and depressive symptom reports. Parents with a preoccupied attachment style reported using more overinvolved, supportive, egocentric, and emotionally insensitive caregiving behavior, as well as having more depressive symptoms. The association between preoccupied attachment


The index of industrial production (IIP) numbers released on Monday seems to have dampened sentiments of the automobile industry. Along with the downtrend, a likely hiring freeze is on the cards.

The index of industrial production (IIP) numbers released on Monday seems to have dampened sentiments of the automobile industry. Along with the downtrend, a likely hiring freeze is on the cards.

“Many companies have gone for production cut,” said P Balendran, vice-president, General Motors India. “No fresh hiring is taking place.”

“There is a need for caution,” said Prince Augustine, executive vice-president, human resources, Mahindra & Mahindra, who heads human capital group of the auto industry body Society of Indian Automobile Manufacturers (SIAM). “It is easy to hire but downsizing is very painful.”

According to SIAM, it is doubtful whether the1. Field of the Invention
This invention relates to a V-type engine, and more particularly to an improvement in the engine cooling system of a V-type engine.
2. Description of the Prior Art
In Japanese Unexamined Patent Publication No. 55(1980)-114845, there is disclosed an arrangement of the engine cooling system for a V-type engine in which the row of cylinders in one bank is rearwardly displaced from the row of cylinders in the other bank in the axial direction of the crankshaft so that a space is formed forwardly of the one bank, and a water pump is disposed in this space, thereby reducing the overall size of the engine.
However, this arrangement is disadvantageous in that the cylinder block becomes irregular in shape, which adversely affects manufacture of the cylinder block,


Talaba Islam Hamadullah Ansari, father Shah Rukh, Hindu leader Dileep Kumar, Riaz Ahmed Abro, Ghulam Sarwar Sadhayo and others said that Modi government had been playing with fire since it came to power. Modi was a terrorist and killer of thousands of innocent people, they said.

They said that incidents of desecration of the holy book of the Sikh community appeared to be aimed at creating a law and order situation. Instead of maintaining peace, police further added fuel to the fire by opening fire on innocent Sikh protesters who were expressing their anger at the sacrilege, they said.

They demanded that the United Nations Organisation and international human rights organisations take immediate steps to stop the Modi government from such provocations and hurting religious sentiments of minorities.

They warned ofwho drove the van containing the shipment of cocaine.

6
In addition, Betancourt was observed driving to Toledo's Fashions with an Hispanic male.   While driving, he continuously used a cellular telephone.   Betancourt was seen speaking with two males inside Toledo's.   During this period, two cars drove to Toledo's.   One of them, a silver vehicle, parked in an alley at the rear of the business.   One of the men with whom Betancourt was speaking drove in a Ford Bronco to the rear of the business to meet the silver car, and both left.   Police later stopped both cars separately.   The Bronco was driven by one of the men with whom Betancourt conversed at Toledo's.   Inside


to establish that the wiretap was necessary.   See 18 U.S.C. § 2518(1)(c), 2518(3)(c).   We review for abuse of discretion the issuing court's factual finding that the government made the required showing of necessity.  United States v. Commito, 918 F.2d 95, 98 (9th Cir.1990), cert. denied, 502 U.S. 879 (1991).

10
The government is not required to "exhaust every conceivable alternative before obtaining a wiretap."  Brone, 792 F.2d at 1506.   We interpret the necessity requirement in "a practical and commonsense fashion, and [wiretaps] need not therefore be used only as a last resort."  United States v. Bailey, 607 F.2d 237, 241-42 (9th Cir.1979), cert. denied, 445 U.S. 93 (1980).   Necessity is established where "normal investigative techniques employing a normal amount }

    void swap(unique_fd& other) noexcept
    {
        using std::swap;
        swap(fd_, other.fd_);
    }

private:
    int fd_;
};

inline void swap(unique_fd& a, unique_fd& b) noexcept
{
    a.swap(b);
}

inline unique_fd invalid_fd() noexcept
{
    return unique_fd{-1};
}


25% OOTV words in the training set vocabulary, 5% in the development set vocabulary, and 9% in the test set vocabulary. We map unseen words using the mapper tuned on the WSJ development set. We use the same Dependency Tree-LSTM experimental settings as Tai et al. Results are shown in Table \[table:lstm\]. We improve upon the original accuracies in both binary and fine-grained classification. [^5] We also reduce the OOTV rate from 25% in the training set vocabulary to about 6%, and from 9% in the test set vocabulary down to 4%.

[max width=]{}

       Fine-Grained                Binary
  ----------------------- ------------------------ --
the drive at the Batcave, Wayne dreams of a post-apocalyptic world, where he leads a group of rebels against a fascist Superman. He is snapped out of the vision by an unidentified being who warns him of Lois Lane‘s crucial role in the future, and urges him to find “the others” before vanishing. Wayne later discovers that Luthor is not only experimenting with kryptonite, but also investigating metahumans. One of them is Prince herself, who is an immortal warrior. Wayne admits to Alfred Pennyworth that he plans to steal the kryptonite to weaponize it, should it become necessary to fight Superman.

At a congressional hearing, as Finch questions Superman on the validity of his actions, a bomb goes off and kills everyone present but Superman. Believing he should have


for 5 min. Amplification products were analyzed by gel electrophoresis on 1.5% agarose gel using a 1 kb DNA ladder as a marker. A gel extraction kit (Qiagen, Valencia, CA, USA) was used for purification of the amplified PCR products and DNA strands of the amplified DNA fragments were then sequenced with the same PCR primers. Sequences of the amplified gene for each isolated yeast were merged in a single nucleotide alignment. Multiple sequence alignment by Florence Corpet was used for alignment of the resulting sequence and relevant sequences available in the GenBank database maintained by the NCBI with manual adjustment when necessary.

Screening for new species among yeasts isolated from wild flowers.
==================================================================

Among 80 yeasts isolated from wild flowers in Daejeon, Korea, 78 were identified based on ITS genec(j) = -3*j - o + j + 1. Let p(t) = 8*t. What is p(c(k))?
-16*k
Let k(w) = -7*w. Let i(t) = 96*t**2 - 194*t**2 + 94*t**2. Give i(k(f)).
-196*f**2
Let o(i) = i**2 - 9*i**2 + 12*i**2. Let r(s) = -2*s - 3. Let k(t) = -t - 1. Let m(l) = -3*k(l) + r(l). Give m(o(z)).
4*z**2
Let s(n) = -415*n**2 + 196*n**2 + 216*n**2. Let y(q) = -6*q**2 - 3 + 3. Calculate y(s(m)).
-54*m**4
Let o(t) = -156*t + 2. Let c(p) = -183*p + 1. What is o(c(h))?
28548*h - 154
Let s(v) = v**2. Let h(n) = -4*n + 4*n + 3*n**2 - 313 + 315. Determine h(s(o)).
3*o**4 + 2
Let z(q) = 2*q + 2. Let i be (1 + 2)/3 + 1. Let f(m) = -m**2 - 3*m -


is c(b(n))?
-8*n**4 - 523
Let k(u) be the third derivative of u**5/30 + 306*u**2. Let j(h) = h**3 - 4*h**2 - 4*h - 2. Let z be j(5). Let i(a) = z*a**2 - 5*a**2 - 2*a**2. What is i(k(d))?
-16*d**4
Let a(v) = 46*v**2. Let o(u) = -284*u**2 + u. Determine o(a(i)).
-600944*i**4 + 46*i**2
Let c(p) = -1403*p**2 + 552*p - 368. Let v(q) = 23*q**2 - 9*q + 6. Let k(z) = 3*c(z) + 184*v(z). Let s(u) = -8*u. What is s(k(d))?
-184*d**2
Let f(p) = 21*p**2 + 26*p - 11. Let g(l) = -11*l**2 - 12*l + 5. Let q(o) = -6*f(o) - 13*g(o). Let c(j) = -j. What is c(q(t))?
-17*t**2 - 1
Let w(v) = 177*v. Let d(b) = 104*b. Calculate w(d(c)).
18408*c
Let f(s) = 144 + 6*s - 281 + 137 -Naringin Abrogates Cisplatin-Induced Cognitive Deficits and Cholinergic Dysfunction Through the Down-Regulation of AChE Expression and iNOS Signaling Pathways in Hippocampus of Aged Rats.
Chemotherapy-related cognitive deficits are a major neurological problem, but the underlying mechanisms are unclear. However, very few studies have looked at the possible ways of preventing this stress-induced deficit. Thus, we investigated the relationship between cisplatin (Cis) exposure to acetylcholinesterase, ATPase, oxidative stress biomarkers, and impaired behavior performance and the possible protecting mechanism of naringin (Nar), a plant-derived flavonoid, in aged rats. The experimental procedures were divided in two sets of experiments. In the first, the animals were divided into four groups: vehicle, Nar 25 mg/kg, Nar 50 mg/kg, and Nar 100 mg/kg. In the second, the animals were divided into four groups: Cis (5 mg


give off the vibe of a casual place to hang out. Given that, I would only recommend coming here if you happen to be on Roosevelt Island anyway. The park is a 15 minute walk from the train station if you’re coming by subway. If you’re driving, you will need to park near the station. (The only parking closer to the park is limited to visitors and staff of the nursing facility nearby.) The park is open from 9 to 7 every day except Tuesdays. No bikes or dogs are allowed.

I seem to find more and more places to explore in Long Island these days. I had never heard of this place until I caught sight of a sign while passing through Oyster Bay one weekend. Planting Fieldsis considered a State Historic Park, but definitely not a place that I would normally think of as a park. It is more of a horticultural center that happens to be on a vast tract of grassy fields, complete with a mansion to drool over. The property was founded by English tycoon William Robertson Coe, a maritime insurer whose company happened to do the insurance for the Titanic, among other ships. His wife was an heiress of the oil industry. Certainly, this kind of money allowed for a very impressive abode on the historic Gold Coast of Long Island.

The grounds are 409 acres, but much of what you want to see is a walkable distance from the estate. There are two greenhouses. The main one has various wings


is today. While I wouldn’t call this a destination, this park has a few things going for it that merit a look if you’re in the area, say, picking up that 3 gallon jar of peanut butter at Costco or visiting the Noguchi Museum nearby. As you can guess by the name, the park has art. Large art. Installations come and go, and sometimes the art is fascinating, and other times it’s just weird and maybe a little uncomfortable. Regardless, there is plenty of lawn space to showcase the creative spirit with the Manhattan skyline as backdrop.

Some other things that weigh in its favor for a visit are the movie screenings in the summer and the greenmarket on Saturdays. There is also the occasional crafts fair. I don’t– it’s so large it has its own golf course. Before you grab that super duper golf club, I do have to point out that it’s limited to a driving range and miniature golf. This park has a dizzying array of recreational spots. In addition to golf, you’ll catch folks enjoying a game of baseball, tennis, soccer, football, handball, basketball, even cricket! There are also plenty of wide open lawn spots for barbecues and picnics.

Look at these guys playing cricket in super white!

Much of the park still holds value as an active ecosystem with wetlands and forests. In fact, it’s considered the most ecologically diverse park owned by the city. If you are a bird watcher, you’re in for a treat. The park hosts hundreds of thousands of


park in Queens, ought to generate some civic pride, but alas, it doesn’t get the same respect as smaller green spaces in the wealthier parts of the city.

What this park does have going for it that’s unique and worth the trek out is its treasure trove of World’s Fair relics. The park was host to not one but two World’s Fairs – one in 1939 and the other in 1964. Most of you have probably seen the Unisphere and the strange rusty towers jutting into the sky on your way to and from LaGuardia, but have you ever taken the step to see these structures up close from the ground? Their imposing facades hide a rich history of people’s hopes and dreams from two different eras. What youswim, this is not the beach for you. Also, if you like to avoid crowds when possible, like I do, I suggest going here during the off-season, from mid-September to mid-April. During this time, you will be able to park at the fisherman’s parking lot off of Beach 193rd St, on Shore Road, rather than at the lot for Jacob Riis Park on the eastern side of the island.

I do recommend parking at the fisherman’s lot so that you can easily walk to the two historical structures that the fort is famous for – Battery Harris East and Battery Harris West. The trail that leads to the Battery Harris West is across from the lot. This is what the beginning of the trail looks like. You can bring


may have to alter your BIOS settings, to make this possible), and when a screen appears asking you to choose between Install Ubuntu and Try Ubuntu without installing, pick the latter.
Open a terminal (Ctrl+Alt+T) and issue these command:
  sudo apt-get install gparted gdisk
Now open gparted (sudo gparted) and erase the partition containing Windows 7. First of all, make sure you are looking at the disk, not at the USB stick: this should be reasonably clear from the partitions size. Also, be careful to choose the right partition, you can identify it from its size, 65.4 GB. Leave the space thus vacated empty, i.e., do not create a new partition in its stead. Execute this operation, close gparted.
Now, from the terminal, issue this command:
 sudo fixparts /dev/sda
which willfor clearances, flight plans, etc. Their information is expensive but indispensible – particularly if you’re doing it in an unusual aircraft (autogyro).

3) Flight clearances are also from other private vendors. International Flight Clearances cc based at Lanseria Airport (Johannesburg, South Africa) is one such company with whom we have had good experience. Tel:- +27 11 701 2330 (24 Hours) Fax:- +27 11 701 2334 Email: flightops@flyifc.co.za.

4) Charts: The best available charts for navigating anywhere in Africa are the ONC’s (Operational Navigational Charts 1:1,000,000) published by the US government NOAA and available from many map companies and pilot shops. http://www.maptown.com/worldaviation/af-1.html is one of them. Google “ONC charts” for a larger list. They are also probably available in Spain. These charts are useful for planning but they are big and


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A:

Hi, I find the solution :)

for using two triggers on one property "Trigger.EnterActions" and "Trigger.ExitActions" should be used instead of using two separate Triggers
excuse me for my bad english :D
Code:
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    <Trigger Property="IsEnabled" Value="True">
        <Trigger.EnterActions>
            <BeginStoryboard>
                <Storyboard>
           Personality disorders and time to remission in generalized anxiety disorder, social phobia, and panic disorder.
This investigation assessed the effect of personality disorders (PersDs) on time to remission in patients with generalized anxiety disorder, social phobia, or panic disorder. Selected Axis I and II predictors of time to remission during 5 years of follow-up were assessed in 514 patients with 1 or more of these anxiety disorders who participated in the Harvard/Brown Anxiety Research Program, a multisite, prospective, longitudinal, naturalistic study. The presence of a PersD predicted a 30% lower likelihood of generalized anxiety disorder remission, a 39% lower likelihood of social phobia remission, and no difference in likelihood of panic disorder remission. More specifically, a lower likelihood of remission from generalized anxiety disorder was predicted by the presence


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ENGIE develops its businesses (power, natural gas, energy services) around a model based on responsible growth to take on the major challenges of energy’s transition to a low-carbon economy: access to sustainable energy, climate-change mitigation and adaptation and the rational use of resources.

ENGIE develops its businesses (power, natural gas, energy services) around a model based on responsible growth to take on the major challenges ofthe opening brief in the Department of Labor’s push to bring a complaint against Uber and similar forms."

Byron Goldstein, an Oakland-based lawyer who is currently representing two clients who are suing Homejoy, the on-demand home cleaning service, told Ars that this new memo is "good news for workers."

"In the 'sharing economy,' for example, many companies have sought to avoid employment laws by proclaiming that their workers are independent contractors," he told Ars. "But, at the same time, these companies not only have substantial control and supervision of their workers but also make it clear to their customers and their workers that it is the company providing the service to the customers."

Uber, for its part, maintains that its drivers want to be independent and enjoy the flexibility, according to