false) }

      // child1
      .down.tapSomeOrFail { assertRole(_, isRoot = false, isLeftMost = true, isRightMost = false, isLeaf = false) }

      // grandchild1
      .down.tapSomeOrFail { assertRole(_, isRoot = false, isLeftMost = true, isRightMost = false, isLeaf = true) }

      // grandchild2
      .right.tapSomeOrFail { assertRole(_, isRoot = false, isLeftMost = false, isRightMost = true, isLeaf = true) }

      // child1
      .up.tapSomeOrFail { assertRole(_, isRoot = false, isLeftMost = true, isRightMost = false, isLeaf = false) }

      // child2
      .right.tapSomeOrFail {off-the-cuff building up of arguments (which at one point included a recitation of Leonard Cohen’s Everybody Knows).

The case for: Clarkson’s position was that the Americans have long had a “strategy” toward integrating Canada within its economic and military sphere, through efforts like free trade and border security agreements. He noted that the power of the U.S. is such that it’s hard for Canadian homegrown industries to compete, which has led to our acceptance of American branch plants dominating our manufacturing sector.

The case against:Granatstein argued that Canada is strong and prosperous because we share the continent with a great democracy. We may think we are different, but there are in fact many similarities between the two nations; he pointed out the ease with which we have adopted American fashions


notion that the United States already effectively controlled Canada, along with his insistence that we shouldn’t get too uppity when questioning American economic and military policies. Perhaps a stronger resolution than one which both debaters seemed to question the wording of might have produced sharper contrasts between their positions. Meanwhile, we hope anyone who raised their hand in support of the resolution won’t be questioned about it next time they cross the Niagara River.immediately when the target's color became random in the subsequent testing phase. In the other set of experiments, we manipulated the diagnostic values of the two colors: Color 1 was more often a target than a distractor; Color 2 was more often a distractor than a target. Participants found Color 1 targets more quickly than Color 2 targets. Importantly, and in contrast to the first set of experiments, the featural preference was sustained in the testing phase. These results suggest that short-term and long-term attentional biases are products of different statistical information. Finding a target momentarily activates its features, inducing short-term repetition priming. Long-term changes in attention, on the other hand, may rely on learning diagnostic features of the targets.


0.951 to 0.977 respectively and decreases the false viability rate (FVR) from 0.712 to 0.652 (see [Appendix](#app1-metabolites-05-00536){ref-type="app"}). Brief summaries of few of the proposed model modifications have been listed in [Table 2](#metabolites-05-00536-t002){ref-type="table"}, [Table 3](#metabolites-05-00536-t003){ref-type="table"} and [Table 4](#metabolites-05-00536-t004){ref-type="table"}. Comprehensive information on the exact cause of disagreement between model and experiment can be found in [Supplemental File S3](#metabolites-05-00536-s001){ref-type="supplementary-material"}. *In silico* analysis also generates results for deletion combinations unexplored so far. For example, box SL2U (see [Figure 1](#metabolites-05-00536-f001){ref-type="fig"}) contains 10 *in silico* lethal gene pairs for which double deletion experiments have been unverified (U) so far in the literature. These unverified results often reveal non-intuitive lethal gene sets to be avoided while designing overproduction strains. Conversely, predicted viable synthetic lethals are prime candidates to be tested experimentally to assess the functionalityFile S1: Table 1](#metabolites-05-00536-s001){ref-type="supplementary-material"}). They generally fill in gaps in existing pathways by introducing *in vivo* verified reactions and the corresponding genes in the model. They also reconcile ESSL2 inconsistencies to SL2SL2 agreements. For example, restoring the *BAT1-BAT2* *in silico* synthetic lethal pair by adding α-keto isovalerate transport between mitochondria and cytosol in the model (see [Table 2](#metabolites-05-00536-t002){ref-type="table"}). Another reconciliation of ESG case to GG case involved an iron (II) transporter reaction being added to the model (see [Table 2](#metabolites-05-00536-t002){ref-type="table"}). Yeast 7.11 contains a low-affinity iron (II) transporter gene *FET4* causing ESG inconsistency. *In vivo* evidence \[[@B58-metabolites-05-00536]\] revealed the presence of a high-affinity iron (II) transporter (encoded by *FET3*) that can also transport iron (II) across the plasma membrane rendering the *FET3-FET4* gene combination an *in vivo* synthetic


the endoplasmic reticulum, which is then transported out to the cytosol and forms a biomass precursor. The existing GPR (see [Figure 6](#metabolites-05-00536-f006){ref-type="fig"}) suggests that either one of *PMT3*, *PMT4*, *PMT5* or both of *PMT1* and *PMT2* need to be present for the reaction to occur. However, recent experimental evidence \[[@B69-metabolites-05-00536],[@B70-metabolites-05-00536]\] implies that PMT genes are classified in the following three sub-families (sub-family 1: *PMT1 and PMT5*), (sub-family 2: *PMT2 and PMT3*) and (sub-family 3: *PMT4*). Literature evidence \[[@B68-metabolites-05-00536]\] suggests that only the removal of *PMT4* in combination with deletions in both sub-family members 1 and 2 is lethal. Therefore, the GPR is modified from *((PMT1 and PMT2) or PMT3 or PMT4 or PMT5)* to *((PMT1 and PMT5) or (PMT2 and PMT3) or PMT4).* This modification puts forth theto verify the viability of all double deletion mutants. Computational tools, such as the SL finder can identify *in silico* synthetic lethal combinations thus narrowing down the combinations to be tested *in vivo*. [Supplementary Tables 3 and 4 (see Supplemental File S4)](#metabolites-05-00536-s001){ref-type="supplementary-material"} tabulate the list of gene pairs and higher order gene deletions in Yeast 7.11 that are *in silico* lethal but have not been tested yet *in vivo*. While the lethal effect of some of these deletions is straightforward, a number of cases reveal non-intuitive lethal deletion combinations from distal parts of metabolism that either hinder cofactor synthesis or transport to another compartment. Four such cases identified using the corrected Yeast 7.11 model are described next in more detail.

### 2.2.1. Proline Auxotrophy (Δ*pro1*Δ*car2* Double Mutant) {#sec2dot2dot1-metabolites-05-00536}

*YDR300C (PRO1)*


1 uses Akg-citrate antiport to translocate mitochondrial Akg to cytosol reversibly, which is coupled to *ctp1* catalyzed citrate-pep antiport. Pathway 2 uses S-malate-Akg antiport to synthesize mitochondrial Akg which is prevented in a Δ*mae1* strain. A Δ*ctp1*Δ*mae1* double mutant is thus both cytosolic and mitochondrial-Akg auxotrophic and thereby is unable to synthesize mitochondrial L-glutamate.

![Valine and Arginine auxotrophy due to simultaneous deletion of *YBR291C* and *YKL029C* gene. Paths 1 and 2 represent two alternate routes to regenerate mitochondrial glutamate and the yellow path shows the part that is common to both paths. Mitochondrial valine goes to valine biosynthesis and 2-acetyl ornithine goes to arginine production. SL gene pairs are marked with red crosses.](metabolites-05-00536-g009){#metabolites-05-00536-f009}

### 2.2.4. Disruption of Lipid Metabolism (Δ*itr1*Δ*ino1*Δ*itr2* triple mutant) {#sec2dot2dot4-metabolites-05-00536}

Lipid (a biomass precursor) is an intermediate metabolitethe number of lethal pairs they were associated with. The graph shows that *pc3,* encoding for diacylglycerol choline phosphotransferase (DCP) activity in phosphatidyl choline (PTC) pathway, is associated with a maximum number of eight synthetic lethal gene pairs (see [Figure 13](#metabolites-05-00536-f013){ref-type="fig"}). For example, *pc3* forms a lethal pair with *pc4* encoding for methylene-fatty-acyl-phospholipid synthase (MPS) reaction. *In silico* simultaneous gene deletion of *pc3* and *pc4* prevents synthesis of biomass precursor PTC synthesis (see [Figure 14](#metabolites-05-00536-f014){ref-type="fig"}). Similarly, *impA2* is associated with four *in silico* SL2 (See [Figure 13](#metabolites-05-00536-f013){ref-type="fig"}). One such case is lethality due to deletion of *impA2* and *ugtLa2* genes, which prevents the synthesis of biomass precursor phosphatidyl myoinositol. Note that the results of node centrality analysis (see [Supplemental File S4: Table 8](#metabolites-05-00536-s001){ref-type="supplementary-material"}) can be utilized to prioritize


Psychological assessment is a process of testing that uses a combination of techniques to help arrive at some hypotheses about a person and their behavior, personality and capabilities. Psychological assessment is also referred to as psychological testing, or performing a psychological battery on a person. Psychological testing is nearly always performed by a licensed psychologist, or a psychology trainee (such as an intern). Psychologists are the only profession that is expertly trained to perform and interpret psychological tests.

Psychological assessment should never be performed in a vacuum. A part of a thorough assessment of an individual is that they also undergo a full medical examination, to rule out the possibilities of a medical, disease or organic cause for the individual’s symptoms. It’s often helpful to have this done first,information from their affidavits, including:  1) that they did not reveal a deal for leniency that the agents made with Ladoucer;  2) that they did not reveal that Ladoucer was violating the law by meeting with Chairman Wall;  3) that they did not explain that some of the targets' admissions were made when the targets were intoxicated;  and 4) that they failed to reveal that the targets had refused to act unlawfully on several occasions.

19
The government contends that the evidence contradicts Tomblin's first two assertions.  The record reflects that the government did reveal that Ladoucer was expecting a deal in return for his cooperation.  The record also reveals that Gonzales testified about the attendees of the meeting with Chairman Wall, and that


U.S. 915, 99 S.Ct. 289, 58 L.Ed.2d 262 (1978).14  Accordingly, Tomblin's challenge fails.

B

23
Next, Tomblin raises several challenges to his convictions for bribery.  He contends that the district court erred in refusing to give his requested jury instruction regarding intent.  He also asserts that the evidence was insufficient to find that he intended to bribe Mauldin.

24
* Tomblin challenges the district court's refusal to grant his requested jury instruction regarding his intent to bribe Mauldin.15  Specifically, he argues that the jury instruction actually given did not require the jury to find an explicit quid pro quo, which is a predicate to the specific intent required.  We review jury instructions for abuse of discretion.  United States v. Pennington, 20 F.3d 593, 600 (5th Cir.1994). Dozier, 672 F.2d at 542 (approving instructions that "fairly presented the issues to the jury").18  Consequently, the district court did not abuse its discretion when it refused to give the instruction Tomblin requested.

2

27
Assuming the instruction was proper, Tomblin also argues that the evidence was insufficient for the jury to convict him of bribery.  See Jackson v. Virginia, 443 U.S. 307, 318, 99 S.Ct. 2781, 2788-89, 61 L.Ed.2d 560 (1979) ("[T]he critical inquiry on review of sufficiency of the evidence to support a criminal conviction must be not simply to determine whether the jury was properly instructed, but to determine whether the record evidence could reasonably support a finding of guilt beyond a reasonable doubt.").  To determine sufficiency in a criminal case:

28
The evidence is reviewed in


the light most favorable to the government, drawing all reasonable inferences in support of the verdict.  But if the evidence viewed in the light most favorable to the prosecution gives equal or nearly equal circumstantial support to a theory of guilt and a theory of innocence, the conviction should be reversed.  It is not necessary that the evidence exclude every reasonable hypothesis of innocence;  the jury is free to choose among reasonable constructions of the evidence.  The only question is whether a rational jury could have found each element of the offense beyond a reasonable doubt.

29
United States v. Pennington, 20 F.3d 593, 597 (5th Cir.1994) (citations omitted);  see also United States v. Stephens, 964 F.2d 424, 427 (5th Cir.1992);  United States v.out-of-state restaurant.  Payment from funds of a business engaged in interstate commerce satisfies the requirement of an effect on interstate commerce.  Coyne, 4 F.3d at 111.   Consequently, the evidence was sufficient to support the jury's finding that the alleged extortion affected interstate commerce.

2

33
Tomblin next contends that, because he was a private citizen, he cannot be convicted of extortion under color of official right.  Usually, only public officials are charged with extorting property under color of official right.  See United States v. Snyder, 930 F.2d 1090, 1093 (5th Cir.)  (discussing trial court's definition that "extortion under color of official right means the wrongful taking by a public officer of money or property not due to the officer or the office"), cert. denied,


502 U.S. 942, 112 S.Ct. 380, 116 L.Ed.2d 331 (1991).  The official need not actually have the powers he threatens to use, nor is the offense limited to elected officials.  See United States v. Freeman, 6 F.3d 586, 593 (9th Cir.1993) ("[T]he Hobbs Act reaches anyone who actually exercises official powers, regardless of whether those powers were conferred by election, appointment, or some other method."), cert. denied, --- U.S. ----, 114 S.Ct. 1661, 128 L.Ed.2d 378 (1994).  Moreover, the victim need not actually know the official's position;  it is enough that the victim reasonably believe the official can do what he threatens.  Stephens, 964 F.2d at 430 (holding that victim need not know extortioner's official position, so long as victim believes extortioner haswas sufficient evidence to support one of the theories presented, then the verdict should be affirmed.  However, if the challenge is legal and any of the theories was legally insufficient, then the verdict must be reversed.

42
United States v. Garcia, 992 F.2d 409, 416 (2d Cir.1993).  The reason for the varying treatment is that jurors can, from their own experience, weed out evidentiary deficiencies,40 but not legal insufficiencies.41

43
Legal insufficiency occurs when, even if the government proved everything it possibly could prove, the defendant's conduct would not constitute the crime charged.  Self, 2 F.3d at 1093 (reversing conviction where, for one theory, "both the government and the district court were mistaken about the law ... and, therefore, Defendant's actions were not within the statutory definition of the


evidence does not apply here.53

3

53
Tomblin next argues that the prosecutor made improper remarks during his closing argument which constitute plain error and require reversal.  When the prosecutor's remarks during closing argument are both inappropriate and harmful, a defendant may be entitled to a new trial.  United States v. Simpson, 901 F.2d 1223, 1227 (5th Cir.1990), cert. denied, --- U.S. ----, 114 S.Ct. 486, 126 L.Ed.2d 436 (1993).  The prosecutor's improper remarks standing alone, however, are insufficient to overturn a criminal conviction.  United States v. Young, 470 U.S. 1, 11, 105 S.Ct. 1038, 1044, 84 L.Ed.2d 1 (1985).  Rather, the defendant must show that the prosecutor's remarks affected his substantial rights.  Simpson, 901 F.2d at 1227.54  "To determine whether the argument affectedand does not constitute bribery.
It must be remembered that TOMBLIN is not required to prove his innocent motivation.  Rather, the prosecution must prove beyond a reasonable doubt that TOMBLIN did not act innocently ....

16
 Although the fact that the court used a pattern instruction is not conclusive, we encourage their use.  United States v. Williams, 20 F.3d 125, 132 (5th Cir.1994) ("[T]he Pattern Jury Instructions provide a useful guide for the district courts, [but] we have never required the trial courts in this Circuit to use any particular language in a jury charge."), cert. denied, --- U.S. ----, 115 S.Ct. 239, 130 L.Ed.2d 162 (1994);  United States v. Turner, 960 F.2d 461, 464 (5th Cir.1992) (affirming refusal to give instruction where judge instructed with Fifth


taking those receipts to Sarasota with him in a shoe box and then asking Robert Dejong to lie to the F.B.I. for him.  Darrell Tomblin didn't deny it and he didn't admit it.  What he did was say, 'Do you have any tapes?   Do you have any tapes?'   When it comes to the crimes charged here--here, we have tapes."

56
 The prosecutor commented:
[I]t was quite clear [defense counsel] and Mr. Tomblin did not want to try the case.  They did not want to appear before you....  This is a case that is truly overwhelming in the strength of its evidence.  Knowing what all the evidence would be, I don't blame them for not wanting the try the case.  Instead,you and ___’. I often see it as between you and I but it really should be between you and me. It is a difficult one to explain but it is because between is a preposition and it should be followed by an objective pronoun – me, him, her etc. It will be interesting if the rule ever changes because it is commonly (but incorrectly) used and therefore becomes acceptable. Keep up your great work.

Thanks for your speedy reply. I think your tips are excellent and I am planning to share them with my class.
I think your sentence is correct. I worked it using your tip to remove the other noun (Eli) and just said it to see if it makes sense – and it did! Top work.
Is


(a) 1/9  (b) 0.3  (c) p
a
Let t = 3.6 + 0.4. Let x be (-24)/(-14) - (2 + 0). Let g = 124664.7 - 124665. What is the second smallest value in 1/10, t, x, g?
x
Let z = -1229.3 - -1230.3. Let f = -5.6 - -6. What is the second smallest value in f, z, 2/7, -6?
2/7
Let n(k) = 17*k**2 - 2*k - 16. Let l be n(4). Let s = l + -1238/5. Which is the second biggest value?  (a) s  (b) 1/7  (c) 3
a
Let n = -0.06 + 0.26. Which is the second smallest value?  (a) 4  (b) 0.8  (c) 1/3  (d) -0.2  (e) n
e
Let h = 4496 + -4810. Which is the fourth smallestvalue?  (a) -3  (b) h  (c) 2  (d) -2
c
Let t = -34/57 + 24/19. Let l = 197 + -200. What is the smallest value in 45, l, t?
l
Let t = -203.137 - -203. Let z = t + -0.863. What is the second smallest value in 4, z, -5, -28?
-5
Let u = 19.93442 - -0.06558. Which is the biggest value?  (a) -0.5  (b) -4.1  (c) u  (d) 1
c
Let x be 55/125*-5 + (3 - 0). Let w = 21 + -83/4. Let q be ((-3)/6)/((-1)/2). Which is the second biggest value?  (a) q  (b) w  (c) -4  (d) x
d
Suppose 108 = 17*t - 15*t. Suppose 57 - t = 3*g. What is the smallest value


to some pharmaceutical companies and health regulatory agencies that govern the entry of certain medications.

This of course has a huge interference regarding the sustainability or otherwise of a product that supposedly has some very admirable virtues but that, as hinted above, still have key differences. Each person experiences in their own way what you believe or what you may believe about this product. The important thing is that the conditions are met to make a deep, serious, research about the alleged or effective actions of this Chinese complement. Thus, of course, there will be a greater control regarding the use of this element which would not harm most or that would not maintained in uncertainty as many people as now.of using a cycolor type photosensitive medium such as a cycolor film, the photosensitive medium is exposed to the optical color image at the optical exposure system, then compressed with a receiver paper by a developing system in order to develop the color image thereof onto a receiver paper which is then heated by the heat fixing system in order to fix the color image thereof.
In the above-mentioned conventional optical exposure system for a color video printer, the number of color gradations of the printed image is substantially influenced by the number of gradations of transmissivities of the liquid crystal elements. Recently, the number of gradations of transmissivities of the liquid crystal elements have gradually increased as the technique for manufacturing the liquid crystal elements have advanced. However,


13 days ([Figure 3A](#f3-opth-6-1623){ref-type="fig"}). Slide culture preparations showed conidiophores that were hyaline and hypha-like, unbranched or branched, and forming a scanty cluster ([Figure 3B](#f3-opth-6-1623){ref-type="fig"}). Conidiogenous cells were phialides occurring on the tips of conidiophores or as side branches of hyphae. These were hyaline, hypha-like, and tapered toward the tops, with an open end and collarette ([Figure 3B and C](#f3-opth-6-1623){ref-type="fig"}, arrows). Phialides were straight or occasionally twisted ([Figure 3B and D](#f3-opth-6-1623){ref-type="fig"}, asterisks). Phialoconidia formed in masses from the open ends. These were hyaline, cylindrical, pointed at both ends, straight or slightly curved at the basal portion, with 0--3 septa (mostly uniseptate), and were 7.0--12.9 × 1.8--3.6 μm (average 10.0 × 2.6 μm) in size. Based on these morphological characteristics, the isolate was identified as *P. tabacinum.*[@b4-opth-6-1623]

A Basic Local Alignmentdiffer from those of *Microdochium* species, where conidia are blastic rather than phialidic. The name *Plectosporium tabacinum* was established by Palm et al in 1995, and has since been widely accepted.

*P. tabacinum* is a rare human pathogen. To our knowledge, only two cases have been reported, including one of fungal keratitis[@b2-opth-6-1623] and one of onychomycosis.[@b3-opth-6-1623] The previous report of fungal keratitis came from Hungary, and was presented in abstract form at the 14th International Society for Human and Animal Mycology World Congress, Buenos Aires, Argentina, in 2000. According to this abstract, a 57-year-old man had developed a corneal ulcer after grass struck his eye while he was weeding. Despite the lack of a pronounced inflammatory reaction, the clinical picture was highly suggestive of a fungal etiology. Corneal scrapings


from contact with a palm tree. In cases of fungal keratitis caused by rare human pathogens, the pathogen is often difficult to detect. We verified the morphological identification of our pathogen by DNA analysis. The pathogen in the case of Simon et al was identified as *P. tabacinum* at the Centraalbureau voor Schimmelcultures, which maintains a world-renowned collection of fungi, but the method of fungal identification was not described in the abstract. The fungus in the case of Theoulakis et al was also identified by a DNA sequence analysis with a BLAST search. Therefore, the ITS sequence analysis is useful for identification or confirmation of uncommon fungal pathogens.

Drug susceptibility testing in our case showed low susceptibility to fluconazole and miconazole, but high susceptibility to voriconazole. Voriconazole, a triazoleComment

Well you know what they say, "It's not the Arrow, it's the Indian..." I did the best I could with the tools available. And now that I've learned I like doing this, please believe I will be investing in better equipment & editing software henceforth!


value is perceived to be available from that source than from a domestic supplier (Leenders et al, 2006).

The first stage, "domestic purchasing only", as the name implies, the company on purchases from domestic supplier (Robert J. Trent & Robert M. Monczka, 2002). Although the company might have international operation, such as, marketing or sales, the purchasing activities do not encompass country borders (Martin, 2007). The reasons to pure domestic sourcing to pure domestic sourcing are many, but could include lack of scale economics, lack of need resources or lack of competencies need to internationalize purchasing activities (Martin, 2007). Reasons for internationalizing purchasing is a primarily to lowest cost, but could also be due to a lack of domestic suppliers (Trent & Monczka, 2003). Marci- economic such as taxdeal with pressure

Understand people well

Observe well

Can handle confrontation

Have sound business judgement

Are skill at dealing with risk and asking questions

Can handle time effectively (Peter et al, 2005)

9.0 (h) Supply Chain Information Systems for Procurement

9.1 Definition of Information Systems

Information supply chain within an enterprise are often more complex, difficult and less systematic than those between with enterprises (Joseph L et al, 2006). Besides that, information system is comprised of interconnected components that process, store, and collect data and distribute information to support, control, decision making and coordination within the organization environment (Leenders et al, 2006). However the information system technology allows the organization to connect with partners or supplier in their supply chain network.

According to Joseph L et al, (2006) state that, the intranet is a relatively secure method to


move business processes online by providing a common interface and communication environment. Data can be input without concern for where the information resides, thus enabling more complete and timely reporting because organization data is to provide (Joseph L et al, 2006). However manual internal processes, such as sourcing, requisitioning, purchasing, receiving, releasing, and contract management, can be performed online to reduce manual and paper-intensive processes (Joseph L et al, 2006). Information systems can be classified to four types, each can consider to serve the requirements and needs of the organization at different levels of management and across functions (refer to Appendix 6) (Leenders et al, 2006).

9.2 The Benefit of Electronic Data Interchange (EDI)

Electronic data interchange (EDI) technology was gives organizations an opportunity to exchange their information and messagegap between where we are and 'best in class' organizations.

The opportunity to creatively incorporate the best practice from any industry into an organization's operations.

Decision support for setting objectives and a basis for cost-benefit analysis.

It is motivating as it identifies objectives that have been achieved by others.

Resistance to change can be diminished when ideas for improved performance come from external sources.

Innovations and technical breakthroughs from other industries can be identified earlier and their applicability assessed.

The experience and knowledge bases of employees can be enhanced (Lysons et al, 2006).

Conclusion

Today, the challenge of global competition is increasingly leading many organizations to replace segmented structures with integrated structures in which purchasing is a part of larger grouping, such as logistics or supply chain management. The ability to relate the effectively to outside


Vegans across the region can rejoice that Millennium is returning this week in the former Box & Bells space in Rockridge. The beloved, high-end, vegan eatery thrived for 21 years, first on McAllister and then on Geary Street, before being forced to close a month ago, but chef chef Eric Tucker and partner and general manager Alison Bagby vowed to reopen in the East Bay and launched a highly successful Kickstarter to help them do so. They landed on the basically turnkey Box & Bells space, cleaned any remaining animal grease off the griddles, put up a new sign, and they'll be making their Oakland debut on Thursday, June 4, as Inside Scoop reports.

As they announce on their revamped website, "After some very incredible years in our locationcompared using ethyl acetate as an extraction solvent. For both techniques, high recoveries from spiked quartz fiber filters (PLE, 82-110%; USE, 67-97%) were obtained. Recoveries obtained from real PM10 samples were also high (76-107%), and no significant matrix effects (ME) on the ionization process (enhancement or suppression) were found (ME, 89-123%). Method limits of quantification (S/N=10) were in the range between 2 and 336 pg/m(3). This method was used to analyze real PM samples collected at several urban and rural locations in the Antwerp area. For the first time, concentrations for Belgium are provided. Concentrations of individual oxy-PAHs are in the lower pictograms per cubic meter to 6 ng/m(3) range. High concentration differences between individual compounds are found as exemplified by the 75th percentile of the phenanthrene-9,10-dione and


We employed 2-photon (2-PE) excitation microscopy by setting the excitation wavelength to 950 nm to co-excite NR and EGFP. For all experiments, spectral images were acquired using the lambda mode 32 channels from 416 nm to 728 nm and a bandwidth of 9.78 nm. The frame resolution was set to 256 × 256 pixels and with a pixel dwell time of 12.61μs/pixel. All data were analyzed using SimFCS software available at ([www.lfd.uci.edu](http://www.lfd.uci.edu)). All cells were maintained at 37 °C and 5% CO~2~ during imaging.

Spectral Phasor Plot and Linear Combination Rule {#Sec3}
------------------------------------------------

Here we employed an elegant way to separate fluorescently tagged protein signal from LAURDAN signal in living cells using a fit-free spectral phasor analysis (Fig. [1](#Fig1){ref-type="fig"}).Figure 1Spectral phasor transformation and the three-component analysis. (**A**) Three spectra for LAURDAN (in a low or high polarity environment, blueWe observed a sharp shift using spectral phasor analysis in LAURDAN emission toward longer wavelength indicating increased fluid membrane in HD in both HEK 293 cells and differentiated PC12 cells. As previously discussed, increased membrane fluidity observed here can be related to the observation due to alteration of biosynthesis of fatty acid or disruption of transport mechanism of lipid in HD. In addition, mHTT toxicity through physical or biochemical means can also result in the cell membrane defects reported here. Such alternation in membrane fluidity can be used as a HD biomarker and also for future drug discovery.

Electronic supplementary material
=================================

 {#Sec12}

Supplementary Figures

A correction to this article is available online at <https://doi.org/10.1038/s41598-018-24031-9>.

**Electronic supplementary material**

**Supplementary information** accompanies this paper at 10.1038/s41598-018-19160-0.

**Publisher\'s note:** Springer Nature remains neutral with regard to jurisdictional


The biosynthesis of menaquinone (vitamin K2) will be studied in bacteria, particularly E. coli and Mycobacterium phlei. The role of 2- ketoglutarate and its addition to shikimate will be investigated by conventional tracer techniques and by the aid of a gas chromatography- mass spectrometer-proportional counting combination. Intermediates will be isolated where possible and structures will be determined for them: in some experiments, the use of inhibitors to cause accumulation of intermediates will be explored. Possible intermediates will be examined to determine whether they can substitute for the vitamin K requirement of the strict anaerobe, Bacteroides melaninogenicus. Finally, individual reactions and their mechanisms will be examined by use of cell-free enzyme systems.is no association between total carbohydrate intake and diabetes risk \[[@B17]-[@B19]\], and other studies reported that total carbohydrate intake is inversely related to HOMA-IR \[[@B20]\].

Current dietary guidelines are recommended for the general population, but emerging evidence suggests an individualized approach involving MNT in accordance with the specific conditions. MNT for Korean individuals with diabetes mellitus involves treatment using dietary choices that consider Korean dietary patterns, treatment, and duration.

In this study, we aimed to investigate the dietary intake of Korean patients with type 2 diabetes according to treatment type and duration and examine the effects of changing dietary intakes on the metabolic risk for diabetes.

Subjects and Methods
====================

Protocol and subjects
---------------------

The subjects were type 2 diabetes patients treated with medical nutrition therapy (MNT group) alone, oral hypoglycemic agents (OHA group), or


duration of diabetes (0.3% per 1 year of diabetes duration; [Fig. 1](#F1){ref-type="fig"}). No independent associations were found for duration with protein percentage of total energy intake.

Clinical characteristics according to treatment type and duration
-----------------------------------------------------------------

The mean values of clinical characteristics according to treatment type are presented in [Table 4](#T4){ref-type="table"}. There were no differences in fasting glucose, postprandial 2 hours glucose, T-Chol, LDLC, hemoglobin, hematocrit, total-protein, and albumin levels according to treatment type. The levels of HgA1c and HDLC were higher in the insulin group than the MNT and OHA groups. However, the level of HgA1c adjusted for duration, age, and sex was not higher in the insulin group compared to the other groups. TG and VLDLC levels were higher in the MNT group than the OHA and insulin groups. HgA1cenergy ratios with triglycerides and total cholesterol

![](nrp-5-157-i005)

The relationship between dietary intake and metabolic risk factors was assessed after adjusting for duration, age, treatment, and sex.

Values are regression coefficients ± SEE (*P* value).

CHO percents, carbohydrate percents from energy intakes; Fat percents, fat percents from energy intakes; Duration, duration of diabetes; Treatment, the types of treatments; INS, insulin treatment with MNT; MNT, only medical nutrition therapy; OHA, oral hypoglycemic agents treatment with MNT; F, female; M, male Adjusted variables were age, treatments, and sex analyzed by general linear model (GLM).

^\*^Dummy codes are 0 = OHA.

^\*\*^Dummy codes are 0 = Male.


and a patient who is asleep (sedated or unconscious). With intubated patients, the waveforms are generally more repeatable, especially for duration and duty cycle of the breath cycle because of the ventilator settings and generally sedated state of the patient. With non-intubated patients the shapes of each waveform are more sporadic.
Several problems are associated with the displaying and usability of prior art moving waveforms, such as the CO2 concentration moving waveforms produced and presented in capnography. These problems include for example the following:                1. The existing Capnographs show a series of two or three waveforms at a time and they are continuously being built up and crossing the screen relative to the patient's1. Field of the Invention
The present invention relates to a non-planar FET and a manufacturing method thereof, and more particularly to a non-planar FET which includes a sub spacer only on a middle sidewall of the fin structure and a manufacturing method thereof
2. Description of the Prior Art
In recent years, as various kinds of consumer electronic products have been constantly developed towards miniaturization and the size of semiconductor components has reduced accordingly, in order to meet requirements of high integration, high performances, and low power consumption for the products.
However, with the miniaturization of the electronic products, current planar transistors no longer meet these requirements. Non-planar transistors, such as fin field effect transistors (Fin-FET), have been therefore introduced to reach a high drive current and to lower short channel


2016 Geospatial Intelligence Hall of Fame.
Dantone flew over 150 combat missions in Southeast Asia. His military decorations include:
 Defense Superior Service Medal
 Legion of Merit
 Meritorious Service Medal
 Air Medal
 Navy Commendation Medal with combat "V"
 Vietnam Service Medal
 Southwest Asia Service Medal
 Kuwait Liberation Medal
 National Intelligence Medal of Achievement

References

Category:Recipients of the Defense Superior Service Medal
Category:Recipients of the Legion of Merit
Category:Recipients of the Air Medal
Category:Recipients of the National Intelligence Medal of Achievement
Category:Living people
Category:Year of birth missing (living people)
Category:Directors of the National Geospatial-Intelligence Agency# frozen_string_literal: false
begin
  require 'win32ole'
rescue LoadError
end
require "test/unit"

if defined?(WIN32OLE_TYPELIB)
  class TestWIN32OLE_TYPELIB < Test::Unit::TestCase
    def test_s_typelibs
      tlibs = WIN32OLE_TYPELIB.typelibs
      assert_instance_of(Array, tlibs)
      assert(tlibs.size > 0)
      tlib = tlibs.find {|t| t.name == "Microsoft Shell Controls And Automation"}
      assert(tlib)
    end

    def test_initialize
      assert_raise(ArgumentError) {
        WIN32OLE_TYPELIB.new(1,2,3,4)
      }

      assert_raise(TypeError) {
        WIN32OLE_TYPELIB.new(100)
      }

      tlib = WIN32OLE_TYPELIB.new("Microsoft Shell Controls And Automation")


accompanying the poll results.

"Employers will have their hands full if a quarter of teens grow up still willing to resort to violence and other unethical behavior when it comes to making decisions about how to settle differences, protect their interests or get ahead," said Miller, who is also author of "God at Work: The History and Promise of the Faith at Work Movement (Oxford University Press, 2006).

There are potential problems with Miller's take on the poll, however.

Teens lie

First, polls can be greatly skewed based on how questions are framed and by how honestly people respond. Adults are known to lie through their teeth in sex surveys, for example. In one Web-based survey, women claimed on average 8.6 lifetime sexual partners. The men claimed 31.9. Some researchers doubt thoseA thrilling 30-ball 55 by Aviwe Mgijima helped the World Sports Betting Cape Cobras consolidate their position at the top of the CSA T20 Challenge table with a narrow three-wicket win over the Multiply Titans at Eurolux Boland Park in Paarl on Wednesday.

The right-hander struck three sixes and three fours for his best career score in a high-scoring affair that saw the 182 for three set by the defending champions chased down with seven balls to spare.

The home side had briefly lost top position earlier in the evening when the Warriors thumped the bizhub Highveld Lions, but regained their spot with a composed victory that put them two points clear with two round-robin games remaining.

They had won the toss and put the Titans into bat but Mark Boucher’s


side responded by amassing a healthy total.

This was thanks in the main to Tony de Zorzi’s 70 off 47 balls (4 fours, 3 sixes) as well as a half-century from Theunis de Bruyn (50 off 37 balls, 4 fours, 1 six).

Farhaan Behardien also provided some fireworks at the end with an unbeaten 39 off 18 balls, which included three fours and two sixes.

After the early loss of Hashim Amla (3), Janneman Malan and David Bedingham struck 37 apiece in a 63-run second-wicket stand that helped the Cobras motor along to 83 for one in the ninth over.

Disaster then struck when Shaun von Berg (1/22) hit back to break the stand, before Junior Dala (3/32) nabbed two wickets in four balls to alter the course of the game.

It wassuddenly 86 for four, but Mgijima and Jason Smith (28 off 18 balls) rebuilt with a stand worth 59 for the fifth wicket.

And by the time the partnership ended, just under 40 were needed from the last five overs, with Mgjima ticking along quickly to carry his side over the line.


 @type Boolean
    @default true
  ###
  autoSelect: true

  ###
    The maximum number of suggestions to show.

    @property items
    @type Number
    @default 10
  ###
  items: 10

  ###
    The number of ms to wait after the user finishes typing before beginning
    the suggestions retrieval process. If your suggestions are fetched
    asynchronously from a server, a bigger number will help to reduce the
    frequency of remote queries.

    @property delay
    @type Number
    @default 10
  ###
  delay: 10

  ###
    The minimum length a search stringsuggestion is set as the value when
    the input loses focus.

    @property autocompleteOnFocusOut
    @type Boolean
    @default false
  ###
  autocompleteOnFocusOut: false

  ###
    The view class to use as the input field.

    @property inputViewClass
    @type Ember.View
    @default 'Emberella.AutocompleteInputView'
  ###
  inputViewClass: AutocompleteInputView

  ###
    The view class to use as the suggestion collection view.

    @property listViewClass
    @type Ember.View
    @default 'Emberella.AutocompleteListView'
  ###
  listViewClass: AutocompleteListView

  ###
    The view class to use for individual suggestion listing views.

    @property itemViewClass
    @type Ember.View


   @default 'Emberella.AutocompleteItemView'
  ###
  itemViewClass: AutocompleteItemView

  ###
    A custom string.replace function to highlight matching strings in
    a suggestion.

    See the "Specifying a function as a parameter" section at
    https://developer.mozilla.org/en-US/docs/Web/JavaScript/Reference/Global_Objects/String/replace
    for additional guidance.

    @property highlighter
    @type Function
    @default defaultHighlighter
  ###
  highlighter: Ember.computed.oneWay 'defaultHighlighter'

  ###
    A custom function for injecting a selected value into the input value.

    @property updater
    @type Function
    @default defaultUpdater
  ###
  updater: Ember.computed.oneWay 'defaultUpdater'

  ###
    A custom function for determining if a string or object should be   @return RegExp
  ###
  stringToSearchExpression: (str, search) ->
    str = str.replace SEARCH_SUBSTITUTION, @escapeSearch(search)
    str = str.replace QUERY_SUBSTITUTION, @expressionFor(search)

    new RegExp(str, 'gi')

  ###
    Shows and hides the list of completion options as the `suggestions` array
    property changes.

    @method suggestionsDidChange
  ###
  suggestionsDidChange: Ember.observer ->
    set(@, 'selected', if get(@, 'autoSelect') then (get(@, 'suggestions.firstObject') ? null) else null)
  , 'suggestions', 'suggestions.length'

  # didRetrieveSuggestions: (search, results) ->

  ###
    Respond to the up arrow key while focus is on the input view.

    @event upArrowPressed
    @param Event e The jQuery keyDown event


Control key is pressed
    @param Boolean meta Meta/Command key is pressed
    @param Boolean shift Shift key is pressed
  ###
  downArrowPressed: (e, alt, ctrl, meta, shift) ->
    len = get @, 'suggestions.length'
    return if len is 0 or alt or ctrl or meta or shift
    e.preventDefault()
    @show().next()

  ###
    Respond to the return/enter key while focus is on the input view.

    @event enterPressed
    @param Event e The jQuery keyDown event
    @param Boolean alt Alt/option key is pressed
    @param Boolean ctrl Control key is pressed
    @param Boolean meta Meta/Command key is pressed
Ember.A()

    for term in source
      do (term) =>
        suggestions.push(term) if matcher.call(@, term)

    suggestions

  ###
    @private

    Trigger action on context.

    @method _triggerRemote
    @param Mixed source
    @chainable
  ###
  _triggerRemote: (source) ->
    context = get @, 'context'
    action = 'searchForSuggestions'

    # Trigger action only if the context will handle it
    # or the source is a string (async/remote search)
    if (typeOf(source) is 'string') or (context? and typeOf(context[action]) is 'function')
      @triggerAction(


In the Greek capital thousands of anti-fascist demonstrators took to the streets in a rally against far-right extremism.

The protest was in response to a planned march by the Greek far-right party Golden Dawn.

Golden Dawn won 17 parliamentary seats in the recent election, but it is unclear if any will be allowed into the chamber as six MPs and the leader of the party are on remand.

The group are accused of creating and participating in a criminal organisation.

Far-right parties from across Europe were invited in a show of solidarity.

Jens Puhse, from the German National Democratic Party (NPD) attended the rally:“We, German nationalists, think that nationalists all over Europe must work together and this is the reason why we are here today to support Golden Dawn.”

Our correspondent Michalis Arampatzoglou inAntenatal diagnosis and obstetric management of Dandy-Walker syndrome.
Real-time ultrasound equipment has the potential for investigating the fetal neural axis and allows the diagnosis of many anomalies arising from this area. Five cases of Dandy-Walker syndrome, one of the major causes of congenital hydrocephalus, were diagnosed antenatally. In all cases ultrasound allowed specific recognition of the defect in the cerebellar vermis. This defect connected the fourth ventricle to a posterior fossa cyst in four cases and to an occipital meningocele in one case. In three cases the diagnosis was made prior to viability, and the parents elected termination of pregnancy. In two cases recognized in the third trimester, neurosurgical care was provided soon after delivery.


drugs there will undoubtedly be some that fail to meet current hopes, but we can be optimistic that a handful will find a useful place in keeping advanced breast cancer at bay for longer than can be achieved at present. However, the holy grail of a cure is likely, in the medium term, to remain elusively at the end of the rainbow for most of these patients. Several other methods for the management of these patients are in development. These include strategies to overcome endocrine resistance and methods to target deregulated endocrine and growth factor signaling pathways using gene and immunotherapy approaches.     logFolder.mkdirs();
    }

    File recordsFolder = new File(Environment.getExternalStorageDirectory() + "/" + main_folder, records_folder);
    if (!recordsFolder.exists()) {
        recordsFolder.mkdirs();
    }
}

The following code gets run on a different thread once the user is walked through a setup menu (requestPermissions just requests permissions normally, the exact code is not important - what is important is that the condition in the first snippet does in fact get satisfied once permissions are granted)
        runOnUiThread(()->{
            if(!(//checks and asks for permissions if necessary


don't think eventually can be today, all right?" "I'm not" "I'm just not..." "Ready." "I got to go." "[Beep]" "Elena." "Hey." "I didn't think you were here today." "Yeah." "No." "I changed my schedule around." "Ok." "Follow me." "[Typing]" "[Beep]" "[Beep]" "Sarah, what are you doing?" "Could ask you the same question." "You can't be in here." "From the look on your face, either you're downloading porn or you're not supposed to be here, either." "What are you doing in Tripp's office?" "What do you want?" "Information on some people who used to live here." "You know anything about the Salvatores?" "Not really." "Well, according to Jeremy," "Zach Salvatore was my dad." "He supposedly died from an animal attack, and, coincidentally, so did my mom, but I've beenno stable complexes with emission in the deep-blue region, which is essential for both high quality displays and lighting. TADF molecules promised to solve these problems in an elegant way (Uoyama et al., [@B26]).

TADF molecules create excited states with strong charge transfer character (CT) which can have vanishingly small electron exchange energies, resulting in nearly equivalent singlet and triplet energies. Using thermal energy to promote the up-conversion of non-emissive triplet states back to the singlet manifold is thus efficient through reverse intersystem crossing (RISC), thereby giving a method of "harvesting" up to 100% of triplet states formed by charge recombination in OLEDs (Dias et al., [@B9]). TADF emitters can thus combine the most desirable properties of metal-carrying phosphorescent emitters, namely 100% triplet harvesting, with the added benefit of


sensitive to the presence of oxygen, temperature, the dielectric medium, and may even vary due to the presence of analytes. As an example, if the TADF molecule selectively interacts with an analyte, most probably this will have a significant effect on the properties of the triplet excited state of the TADF emitter. These changes will be inevitably reflected in the TADF efficiency and lifetime (Chen and Song, [@B5]).

The DF component can be used as a long-lived luminescence to enable time-gated acquisition methods that ignore nonspecific and non-negligible resolution-limiting signals from autofluorescence and light-scattering (Zhao et al., [@B34]). For these reasons, TADF emitters have attracted significant scientific interest as an alternative to heavy metal-based complexes in optical imaging (Chen and Song, [@B5]). Despite these very interesting properties the applicationof TADF molecules in the optical imaging and sensing remains largely unexplored. Since most TADF dyes are weakly soluble in water and show very weak luminescence in polar solvents due to their charge transfer properties, their direct use in biological media has been critically hindered. To overcome these drawbacks, TADF emitters have been encapsulated in macromolecules (Xiong et al., [@B30]), precipitated onto nanoaggregates (Ni et al., [@B18], [@B19]; Zhu et al., [@B35]) or assembled in amphiphilic polymer micelles with other small-molecular-weight dopants (Li et al., [@B13]; Luo et al., [@B14]; Tsuchiya et al., [@B25]). In addition, we previously reported the preparation of TADF emitting silica nanoparticles using a simple doping procedure with a silane-bearing TADF derivative (Crucho et al., [@B6]). These approaches were successful in achieving TADF emission


fluorescent nanoparticles exhibit improved biocompatibility, photostability, and optical brightness when compared to free dyes, and find application in biological optical imaging, theragnostic, and chemical sensing (Montalti et al., [@B17]; Li et al., [@B12]). In this work, we describe the preparation of TADF emitting polymeric nanoparticles using a simple straightforward swelling procedure, which is advantageous for the encapsulation of dyes with strong potential for generalization. Two well-studied TADF emitters (Wang et al., [@B27]; Dias et al., [@B8]) were selected and encapsulated in polystyrene (PS) nanoparticles. PS is a versatile and attractive matrix for dye encapsulation, being commercially available as nanoparticles in a broad size range and has been extensively used in the encapsulation of organic and inorganic fluorophores for imaging and sensing applications (Mader and Wolfbeis, [@B15]; Lee etthe high hydrophobic character of these particles, stable aqueous suspensions are usually difficult to obtain from aggregated PSPs. For this reason and because aggregation could reduce cellular uptake, the centrifuged pellets were discarded and the supernatants were extensively dialyzed against water to remove surfactant molecules and traces of unreacted styrene monomer, which are the main source of PSPs cytotoxicity. The washed suspensions were characterized by TEM and exhibited nanoparticles of spherical morphology with diameters of 32 ± 4 nm, as shown in [Figure 1A](#F1){ref-type="fig"}. The amino-modified particles (PSNH~2~) were also imaged by TEM, showing spherical morphologies with diameters of ca. 100 nm ([Figure 1B](#F1){ref-type="fig"}).

![TEM images of the unloaded nanomaterials PSP **(A)** and PSNH~2~ **(B)**. Scale bar = 100 nm.](fchem-08-00404-g0001){#F1}

Both dyes, **1** and **2**, were loaded into PSP and


loaded with dye **2** ($\lambda_{\text{em}}^{\text{PS}3} =$539 nm vs. $\lambda_{\text{em}}^{\text{PS}4}$ = 555 nm) than those with dye **1** ($\lambda_{\text{em}}^{\text{PS}1} =$550 nm vs. $\lambda_{\text{em}}^{\text{PS}2}$ = 556 nm), due to the different polarity sensitivity of both dyes, in terms of optical properties.

![Normalized steady-state emission spectra of free dyes (black) and dye-loaded neutral (blue) and charged (red) nanoparticles in aqueous suspension: **(A)** dye **1**, **PS1**, and **PS2**, λ~ex~ = 340 nm; **(B)** dye **2**, **PS3**, and **PS4**, λ~ex~ = 420 nm.](fchem-08-00404-g0002){#F2}

The effects of encapsulation on the luminescence quantum yields are also evident. Comparing the prompt fluorescence quantum yields of dye **1** in solution with those of materials **PS1** and **PS2** in aqueous suspension, it is evidenced the encapsulation into polystyrene nanoparticles enhances the prompt emission quantum yield (Φ~PF~) in fluid media, takingremoval of oxygen ([Figure 5](#F5){ref-type="fig"}). However, the increase in intensity due to oxygen removal is less than that observed for dye **1**. [Figure 6](#F6){ref-type="fig"} depicts the time-resolved emission spectra of **PS3** and **PS4**, suspended in water, where it is evidenced that a delayed fluorescence component is observed in the microsecond time range ($\lambda_{\text{em}}^{\text{TADF}}$ = 571 nm for **PS3** and $\lambda_{\text{em}}^{\text{TADF}}\  =$ 581 nm for **PS4**). Similarly to what is observed for materials loaded with dye **1**, both materials also exhibit a blue-shifted phosphorescence in the millisecond time-scale ($\lambda_{\text{em}}^{\text{Phos}}\  =$ 559 nm for **PS3** and $\lambda_{\text{em}}^{\text{Phos}}\  =$ 553 nm for **PS4**). Probably due to polarity effects, the PLQY value is ca. 3 times higher for **PS3** than for **PS4**, affecting both Φ~PF~ and Φ~DF~ values. Nevertheless,


in distilled H~2~O for \~15 min and rinsed thoroughly with distilled H~2~O. All chemicals employed for synthesis were of reagent grade from TCI and used as received. For optical measurements, solvents were of spectroscopic grade and used without prior purification. Toluene was PA grade and was dried using metallic sodium and benzophenone and distilled before use. Tetrahydrofuran (THF) was of UV-spectroscopic grade and purchased from Sigma-Aldrich. Deionized water purified using a Millipore Milli-Q system to a resistivity of 18.2 MΩ was used throughout the experiments unless otherwise stated. Argon (Ar) gas (Alphagaz 1, 99,999%) was purchased from Air Liquid. Reagents and solvents used in synthesis were all analytical grade.

Dye and Particle Synthesis/Preparation
--------------------------------------

### Synthesis of DPTZ-DBTO~2~ (1)

The synthesis of **1** was carried out according to a previously reported strategyinto the 96-well plate and cultured for 24 h at 37°C in 5% CO~2~ atmosphere. Then, **PS3** and **PS4** at different concentrations (0--100 μg/mL) were added in duplicate and incubated for additional 24 h. After the incubation period, media was carefully replaced with 100 μL of fresh complete media without disturbing cell contents followed by addition of 20 μL of MTT solution (5 mg/mL) and incubated for 3--4 h. Finally, the formazan crystals formed in the wells were dissolved using 150 μL of MTT solvent and the absorbance was read at 590 nm using a microplate reader (bmg labtech 96 Spectrostar Nano).

Data Availability Statement {#s5}
===========================

All datasets generated for this study are included in the article/[Supplementary Material](#SM1){ref-type="supplementary-material"}.

Author Contributions {#s6}
====================

Experimental: CC did the nanoparticle synthesis and characterization. JA did the


this one" while Martha says awkwardly, "Foshizzle."

This content is imported from Third party. You may be able to find the same content in another format, or you may be able to find more information, at their web site.

Follow Delish on Instagram.

This content is created and maintained by a third party, and imported onto this page to help users provide their email addresses. You may be able to find more information about this and similar content at piano.ioDuring the brief heyday of Southern California’s turf removal rebate program, 17 Orange County country clubs, cities and homeowners associations got rebate checks of more than $100,000 for tearing out turf and replacing it with drought-tolerant plants, according to records.

The country clubs were part of a flood of rebate applications from homeowners and businesses that drained several hundred million dollars from the Metropolitan Water District’s reserves in a matter of months, leading the district to institute caps on maximum rebates and, eventually, shut down the program for lack of funds.

The six-figure payouts – in the county’s largest payout, one country club got $1.9 million – were funded largely by unexpectedly high water sales in recent years and came in the form of bills collected from homeowners, businesses and


businesses.

El Niguel General Manager Eric Troll did not respond to messages seeking comment.

No other business in Orange County collected more than $1 million. The next highest was just over $500,000. The highest residential rebate here was about $32,000.

Homeowners were issued 10 times as many rebates as businesses. But the businesses collected more money total – more than $9.9 million compared with just over $7 million. The average commercial rebate was also more than 14 times higher than the average residential rebate.

In Orange County, 345 commercial rebates were handed out, and the average was more than $28,800. Homeowners got roughly 3,500 rebates, with an average of $2,014.

After El Niguel started its headline-making renovation, MWDOC’s phones started ringing off the hooks with applications from other golf courses. Some didn’t applytiered rates. The rebate money comes from a pool that includes those water bills.

“You’re not just returning money. You’re returning money in a way that’s going to have a lasting and durable impact,” Feldman said.

LOW-INCOME HELP?

Any way you cut the checks, given California’s long love affair with water-sucking grass, the breakup is bound to be expensive.

“You have to start somewhere. We’ve invested in a certain kind of aesthetic in the region for many, many years, when water wasn’t such an inhibiting factor as it is today,” Feldman added.

The next step, he suggested, might be finding ways to open the turf rebate program to low-income homeowners. Currently, homeowners must first pay contractors to redo their lawns – the rebate comes later.

The turf rebate program has not been without its


since 1960, Sunset has staged at least one production geared expressly for families as an outreach and educational service. The program includes a repertoire of original plays written expressly for the Sunset audience. An "invited audience" program has been an important part of the children's theatre project. It has allowed us to perform for many metro Milwaukee children and other residents who might not otherwise experience live theatre. Sunset has been honored by Milwaukee County for our efforts with County institutions on behalf of children and adults.present in both samples are iron, zinc and lead with minor amounts of manganese, calcium and silicon. The dominant mineralogical phases identified in both materials are Magnetite, Franklinite and Zincite. The recent sample has Laurionite whereas the weathered sample has Hydrocerussite and Hydrozincite.


Pulmonary receptor discharge and expiratory muscle activity.
Expiratory activity in abdominal muscles can be elicited when animals breathe against a continuous positive airway pressure (CPAP). To evaluate possible pulmonary receptor mechanisms underlying this effect, graded bilateral vagal cooling was used to inhibit expiratory discharge of abdominal muscles in anesthetized adult opossums during CPAP (6-8 cm H2O); then the discharge patterns in fibers from slowly adapting pulmonary stretch receptors and rapidly adapting pulmonary receptors were assessed when cut vagus nerves were cooled to temperatures similar to those required to inhibit expiratory muscles. Expiratory motor responses were completely inhibited by cooling the vagi to a mean temperature of 9.6 degrees C (range: 7-12 degrees C), but concurrently observed augmentation of amplitude and duration of inspiratory (diaphragm) discharge continued with further loweringthen transferred onto a 96-well plate and irradiated with the laser. All samples were then again returned to the incubator for various periods of time (0.5 h; 1.5 h; 3 h; 4.5 h; 6 h; 12 h; 24 h). After the respective incubation time, 350 µl of RLT-Buffer (Qiagen, Hilden, Germany) were added to each sample to disrupt the cells and total RNA was extracted from Rb-cells by using the RNeasy Mini Kit (Qiagen). The quality of the RNA was analyzed by agarose gel electrophoresis. The A~260~/A~280~ ratio of optical density was measured using the GeneQuantpro device (Pharmacia, Uppsala, Sweden), and was between 2.0 and 2.2 for all RNA samples, indicating sufficient quality. After treatment with DNase I (Roche, Mannheim, Germany), cDNA was synthesized from 1 µg total


cell cycle further driving apoptotic cell death [@pone.0087453-Peng1]. GADD45G increase reflects the stressful growth arrest conditions via treatment with DNA-damaging agents [@pone.0087453-Takekawa1]. Increased GADD153 also participate to the arrested cell growth and promote programmed cell death, in part via activation of AP1 target gene [@pone.0087453-Ubeda1]. Last but not least, it has been shown that cytosolic heat shock proteins such as HSP105 are preferentially induced in response to specific and localized intramitochondrial damage [@pone.0087453-Ho1]. The induction of apoptosis was also suggested by the chromatin condensation (pyknotic nucleus) and the karyorrhexis (nucleus fragmentation) seen in Rb cells treated with mild THPTS-PDT (25 µg/ml, 90 min). Together with cytoskeletal restructuration and membrane blebbing, those damaged nuclei are hallmarks of the undergoing apoptotic process. Altogether, our results demonstrate that THPTS-PDT leads toto patent the methodology or to protect further any of the information contained in this article. This situation does not alter the authors\' adherence to all the PLOS ONE policies on sharing data and materials.

[^2]: Conceived and designed the experiments: SS PW JN TC. Performed the experiments: JW SDS JN TC. Analyzed the data: JW SS SDS PW JN TC. Contributed reagents/materials/analysis tools: SS JN TC. Wrote the paper: JW SS SDS JN TC.


to the relief bore's dump.[ we once again interrupt this broadcast to announce the following Type 4 Oil Filter Bypass bulletin:There is another relief valve inside the oil filter mount that opens at only 9-12 psi.This does not mean that it opens every time there is more than 9 psi oil pressure in the engine. A well-maintained filter can flow 4 gpm of factory specified viscosity at 34*, that is what your positive displacement pump flows at 3,500 rpm dead cold, so don't . . . do that. Only if/when the filter cannot maintain a *flow rate* that is within a 9-12 psi differential between the filter's own "in" and "out" will the relief open. This occurs only very briefly when the engine is cold and the galleriesorders at the indicated levels.

“While the candle gives the impression that liquidity was exhausted between $8–12k, the wicks on either side are hollow,” adds Kraken. “Stops in the range of $8–12k were triggered. Stop market orders were correctly filled at market price (best bid/ask available).”

The exchange also recommended that users involved in the incident contact them to clarify their questions, later publicly announcing that they would not roll back transactions and take on any losses incurred. At the same time, they could not avoid their share of criticism due to the execution of stop orders.

“So, because a bug is discovered in a limited production beta once every few years it means there’s no testing? Our new order types undergo thousands of automated and human tests for months before


to the infantry unit. So for a command to go from Marshal Beresford, to Major General Stewart to Colborne’s Brigade will take a minimum of 14 minutes of game time plus additional time penalties based on the leadership abilities of Beresford and Stewart.

Lastly, the leadership of Colborne’s Brigade is used to calculate how quickly the unit will act upon the received orders. This is an example of the detailed Simulation mode for General Staff.

However, in Kreigsspiel mode, all headquarters units are removed and the user issues orders directly to the units that immediately respond to the commands.

Also, all unit information except a simple value (1-4) is ignored. Kriegsspiel mode is the simple, introductory wargame that I originally envisioned.= 0x1F;
        public const Int32 InverseDecalTypeMask = 0xE0;
        public const Int32 DecalTypeShift = 0x0;

        // Byte - [0001 1111] Ramp Type
        //        [0010 0000] Sunlight
        //        [0100 0000] Explored
        //        [1000 0000] Player built voxel
        public const Int32 RampTypeShift = 0x0;
        public const


vesicles of \~100 nm in diameter.

ECL‐based assay system {#acn3264-sec-0010}
----------------------

The Meso Scale Discovery (MSD, Gaithersburg, MD) assay platform utilizes Ruthenium (II) tris‐bipyridine‐(4‐methylsulfone) \[Ru(bpy)3\] for detection. The Ru(bpy)3‐based tag (sulfo‐tag) undergoes a rapid redox reaction that emits light in the presence of an applied voltage.[28](#acn3264-bib-0028){ref-type="ref"}, [29](#acn3264-bib-0029){ref-type="ref"} The assay was performed using high‐bind plates (384‐well) at room temperature. Briefly, 1 *μ*g of membranes was added to each well for 1 h followed by blocking with 25 *μ*L of blocking solution composed of 3% Bovine serum albumin (BSA) and 1% skim milk powder. As negative control, Phosphate‐buffered saline (PBS) buffer instead of membranes was applied. Subsequently, the plate was washed with washing buffer (50 mmol/L Tris pH 7.5, 0.15 mol/L NaCl, 0.02% Tween‐20). 25 *μ*L of CSF samples diluted in PBS (1:5)Subsequently, 25 *μ*L of 1:5 diluted CSF samples were added for 1 h, followed by washing steps. The plates were then incubated with anti‐human IgG sulfo‐tag antibody for 1 h. After washing, the reading buffer was added and the ECL signal was measured with the SECTOR Imager 6000. Experiments were performed with the operator being blinded for the patients′ diagnosis.

Statistical analysis {#acn3264-sec-0012}
--------------------

To analyze the ECL‐based data, two‐way analysis of variance (ANOVA) was performed using IBM SPSS 20 statistical software, Armonk, NY, USA. For cytotoxicity analysis, one‐way ANOVA was performed. Values are expressed as mean ± standard deviation of the mean (SD). Univariate analysis was performed to evaluate the association of CSF total protein concentration, serum albumin concentration, CSF albumin concentration, albumin CSF/serum ratio, CSF IgG concentration, serum IgG


concentration, IgG Index, ECL antimyelin score, and confirmed diagnosis of MS. Multivariable logistic regression was conducted including variables with significant association with confirmed MS diagnosis in univariate analysis. The ability of ECL score to help with identifying MS was evaluated by receiver operating characteristic (ROC) curves.[30](#acn3264-bib-0030){ref-type="ref"}, [31](#acn3264-bib-0031){ref-type="ref"} The analysis was conducted firstly among all the patients regardless of presence of OCBs, and subsequently performed only within patients with CSF OCBs. We calculated the area under the ROC curve (AUC) and its 95% confidence interval. We compared the AUC value ECL antimyelin score and IgG index, which was recommended as an supportive marker for MS diagnosis by the 2010 McDonald criteria.[23](#acn3264-bib-0023){ref-type="ref"} Logistic regression and area under the ROC curve are two standard methods evaluating biomarkers.[32](#acn3264-bib-0032){ref-type="ref"}, [33](#acn3264-bib-0033){ref-type="ref"}, [34](#acn3264-bib-0034){ref-type="ref"}, [35](#acn3264-bib-0035){ref-type="ref"} Logisticantibodies against neuronal, astrocytic, and myelin proteins (Methods see Data S1, Fig. S1).

To obtain a sensitive and quantitative detection system, we set up a custom‐designed ECL‐based assay. Myelin particles were absorbed to carbon‐coated plates and the specificity of the assay system was evaluated with antibodies against myelin proteins and control antibodies followed by secondary sulfo‐tag‐coupled antibodies. A membrane fraction depleted of myelin was used as a reference (nonmyelin fraction). Myelin protein antibodies showed higher reaction toward myelin than nonmyelin (ratio \> 1), verifying the specificity of this method and serving at the same time as the positive control for further antibody detection (Fig. S2). Multiple trials in which the fractions were placed at different plate locations were conducted at different time point. No significant intra‐assay variability was observed.


\< 0.001). (B) The CSF reactivity of 43 MS OCB ^+^, 25 OND OCB ^+^, and 14 OND OCB ^−^ patients was tested in an ECL‐based liposome assay against wild‐type myelin liposome (WT M), and *CerS2* KO mice myelin liposome (CerS2 KO M). The CSF reactivity of MS OCB ^+^ patients against WT M was significantly higher than toward CerS2 KO M (*P* \< 0.01). The CSF reactivity of OND OCB ^+^ and OCB ^−^ patients against WT M and CerS2 KO M were not significantly different (*P* \> 0.05). (\*\**P* \< 0.01, \*\*\**P* \< 0.001) CSF, cerebrospinal fluid; KO, knockout; MS, multiple sclerosis; OCB, oligoclonal bands; OND, other neurological diseases; ECL, electrochemiluminescence.](ACN3-2-1116-g003){#acn3264-fig-0003}

Using ROC curve, we analyzed the ability of the ECL score against myelin particle in diagnosingbilayered liposomes as a method to prepare artificial membranes with a defined lipid composition. This allowed us to indentify cerebroside‐specific antibody reaction in a subpopulation of MS patient. There was a strong correlation between the reactivity of CSF toward myelin particles and liposomes containing cerebrosides suggesting that antibody responses against myelin were primarily directed against cerebrosides.

Lipid(s) and the autoantibody response toward lipid(s) in serum and CSF have been increasingly investigated as biomarkers.[3](#acn3264-bib-0003){ref-type="ref"}, [11](#acn3264-bib-0011){ref-type="ref"}, [17](#acn3264-bib-0017){ref-type="ref"} Our study is unique that we were able to isolate purified myelin particle without detergent and immobilize the particle in a highly sensitive assay. The platform developed in our study allows detection of a combination of different lipids using synthesized liposomes. The high AUC value of the ECL myelin score indicated its potential as


nonfiction works, including articles in the gaming magazine Knights of the Dinner Table and an ongoing blog at BabyCenter.com.

Charlie is a lifelong resident of Vermont, having been born and raised in the town of St. Johnsbury. He received an English degree at the University of Vermont, where he met his future wife Sarah. In 2008 he changed his name to Charlie Brooks in honor of the man who raised him. He now lives in St. Albans, Vermont with Sarah and their son Quentin.stars, including Sting, Michael Jackson, Ringo Starr and Tony Bennett, with whom Gaga collaborated on a rendition of "Lady and the Tramp," for his album, "Duets II."

Will Gaga turn Lisa into one of her "monsters?" Tune into the May 20th finale, titled "Lisa Goes Gaga" to find out!


streamer. It "functions as a media player" and requires an external power source. The power source rules out any sort of wireless battery-powered device, indicating this is, in fact, designed to stay put. In addition the new gadget was tested on a 24 inch dell monitor, indicating that it's designed to output to an external display. Oddly enough the two were connected via USB.

The original Nexus Q was a cool idea. Being able to stream music and video to your TV, all while controlling it with your smartphone, would've been fun. Unfortunately for Google, the Q was pitted against all kinds of cheaper, android powered set-top boxes. Those boxes could not only play video and music, they could run actual applications. While they may not have been nearlyEffect of histidine-free and -excess diets on anserine and carnosine contents in rat gastrocnemius muscle.
Anserine and carnosine contents were determined in muscle of rats subjected to histidine depletion or excessive supplement. The contents of anserine and carnosine were reduced in the gastrocnemius muscle of rats fed a histidine-free diet. The diet showed especially a remarkable decrease of carnosine content. After rehabilitation for one week, the muscle anserine and carnosine contents in histidine-deficient rat returned to the normal level. The body and gastrocnemius muscle weight were decreased in rats fed a histidine-excess diet. However, anserine and carnosine content in muscle of rats fed a histidine-excess diet were twice of that of control rats. Urinary excretion of Npi-methylhistidine and Npi-methylhistidine was increased in rats fed a histidine-excess diet.


presidential straw poll conducted by the Independence Party of Minnesota.

Results

Key results:

 The table is meant to show all the contests Edwards competed in and won, not a complete list of primary states. That is to say everything on Super Tuesday and Before as well as North Carolina should be included in the table.

 Edwards won the nominating Contest (North Carolina and South Carolina)
Edwards came in either 2nd or 3rd place in the nominating contest (Iowa, Delaware, Missouri, Oklahoma, Michigan, Tennessee, Virginia, Nevada, Wisconsin, Hawaii, Utah, California, Connecticut, Georgia, Maryland, Massachusetts, Minnesota, New York, Ohio, Rhode Island, Vermont)
 Edwards came in 4th Place or Below in the nominating contest (New Hampshire, Arizona, New Mexico, North Dakota, Washington)

After withdrawal

Surprise North Carolina win
After withdrawing from the race, he went on tothe left hand while ducking his or her head under uke’s right arm and grabbing uke’s right thigh with the right arm. Tori must squat low while keeping the back upright so that uke rests squarely on tori’s shoulders with his or her belt directly behind tori’s head.

Tori throws by continuing to pull with the left hand while lifting with the right arm so that uke is wheeled over the shoulders of tori.

Welcome to the official Judo Information Site.
Please enjoy the online lessons at the original injury-free Kodokan Judo virtual dojo.
If you have any questions that are not answered on JudoInfo.com, feel free to contact us.


regulation for complex diseases, since genes interact with each other in complex regulatory networks. For example, gene coexpression networks comprised of modules of genes demonstrating high levels of co-regulation^[@CR6]^.

We implemented a systems genetics framework to integrate genetic loci identified from the largest BMI GWAS meta-analysis with gene expression profiles in adipose tissue from 200 subjects to explore underlying molecular mechanisms for obesity (Fig. [1](#Fig1){ref-type="fig"}). Genetic loci associated with diseases from GWAS can perturb specific parts of gene networks, whose overall dysregulation may shift homeostatic processes and lead to disease^[@CR4],\ [@CR7],\ [@CR8]^. Using weighted gene coexpression network analysis (WGCNA), we identified modules composed of genes that were highly interconnected with one another and displayed significant associations with obesity and related metabolic traits. Through characterization of module content and topology, weBoston, MA, and Baton Rouge, LA, in 2004--2007. The study was approved by the human subjects committee at the Harvard School of Public Health and Brigham and Women's Hospital, Boston, MA; the Pennington Biomedical Research Center of the Louisiana State University, Baton Rouge, LA; and a data and safety monitoring board appointed by the National Heart, Lung, and Blood Institute. All participants gave written informed consent. Detailed information on the The POUNDS LOST Trial study design and methods was previously described^[@CR36]^. Major criteria for study exclusion were the presence of diabetes or unstable cardiovascular disease, the use of medications that affect body weight, and insufficient motivation.

A total of 811 overweight or obese subjects (BMI ≥ 25 and ≤ 40 kg/m^2^), age 30--70 years, were randomly assigned to one of weight loss diets. Each


data analysis. G.A.B., F.M.S. and L.Q. contributed to the study concept and data acquisition. H.S., W.C. and L.Q. provided comments and suggestions for the manuscript. H.H. and H.W.D. contributed to study concept and design, the critical revision of the manuscript, and administration, material support, and study supervision. All authors contributed to interpretations of data and to revisions of the manuscript. H.H. and H.W.D. are the guarantors of this work and had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Competing Interests {#FPar1}
===================

The authors declare that they have no competing interests.
to achieve an 82%>.

Embracing and promoting our organization's Zero Accident Culture through communications along with the motivation and drive to get us there, will help us to succeed in achieving this goal.

The second area is with our internal management of claims. Every claim should be tracked and an employee's medical status monitored weekly. There needs to be verbal communication with the employee on a weekly basis, whether the employee is at work or disabled from work to assure they are following their medical care plan. (Early Return to Work and control of medical costs) This will serve to obtain the latest medical updates and dates of follow-up visits to doctor.

Conclusion

Medical claim costs are on the rise in healthcare. As more staff become active in reporting work-related injuries, some


flaw or a dirt, data acquired on all lines are integrated to generate shading image data as flattened data, a difference between the original data and the shading image data is calculated, and when the difference shows a singular point larger than a prescribed value, the singular point is determined to be a singular point due to the defect (refer to e.g. Japanese Patent Application Laid-Open No. 2006-050356).listeners learn more about your classes and contact you?http://cjhsla.org/jewscanshoot/2014/10/28/home-defense-personal-protection-inside-the-home-sunday-nov-30-shoot-safe-learning/

Segment 4 DGUs
-A Tuscaloosa woman has a stalker. He called her earlier in the day and threatened he was coming over to kill her. She fired two cartridges from her shotgun when he pulled up in her driveway. The stalker left and then called for an ambulance after being struck in the neck by the shotgun pellets. He was treated at a local medical center where police investigators discovered his history of domestic violence. He was charged with stalking and trying to set this woman’s house on fire last April. Witness confirmed what happened this week, and the stalker was arrested again, charged with third-degree domestic violence harassment, and booked in the County Jail.

-The shop keeper closed the store without


We keep fighting to restore and preserve the 2nd Amendment, but the forces against us continue, and seem to be gaining strength in a perpetual tug-of-war.

Is it time we realize this fight will continue forever? Is it time we realize there are just some factions in this Nation who will never accept our civil rights, will never accept the 2nd Amendment, and will fight as long as we fight? A never-ending battle. I do have a solution.

Is it time we accept the reality that we have Free States and Slave States? A house divided against itself cannot stand. Perhaps we should not repeat the First Civil War, and rather than enter into a Second Civil War, we should just accept the reality and break into 2 separate Countries?Ginny Burdick (D-Portland) says that “We have a working majority for background checks.” Currently, Oregon requires background checks for sales by a gun dealer or at a gun show. It is unclear if the as of yet unwritten legislation will just cover sales or will include transfers. The effort for background checks fell short in the last session of the Oregon legislature.

-The ten worst anti-knife cities stand out for their outright persecution of honest knife owners and extraordinarily restrictive anti-knife ordinances, far more severe than even the state laws in those areas. All too often this results in unwary citizens being subject to arrest and prosecution, and loss of their knives, for having a knife that is perfectly legal elsewhere in the state.

New York, NY (majority of pocketknives


health protections were far more effective. Now he says “My goal is to educate the public, because the mainstream media and the governor’s office are intentionally lying to people,”

After the hearing, Ms. Paskel explained why she ordered McCauley not to answer. The testimony “was not about policy; it is just [about] votes.”

-There is more news about Maryland assault on civilian long guns. 21 State Attorneys General filed an amicus brief opposing Maryland’s gun ban. The brief was filed in the U.S. Fourth Circuit Court of Appeals in the case of Kolbe v. O’Malley. The States Attorneys said Maryland’s Firearm Safety Act violates citizens’ rights to keep and bear arms by imposing a ban on the possession of commonly-used weapons. They also said Maryland law must be subject tocalls, but that’s not always possible. Now they carry concealed and spend a day at the range to brush up on their skills.

Quote, “Because we deal with such a wide variety of real estate from the high-end stuff.. all the way down to the very lowest of low.. we never know what we’re walking into,” said Kevin Craig. Some ranges in Tempe now offer monthly self-defense courses for realtors.

-A gun owner is suing the Atlanta Botanical Gardens after he was escorted off the property because he was openly carrying a permitted gun. Phillip Evans and GeorgiaCarry are bringing the lawsuit. The Botanical Gardens allow “no weapons except as permitted by law.” Since open carry by licensed firearms owners is legal in Georgia, Evans visited the gardens while armed.


that hunting over a baited trap if you dog is tied on a lead, and a bear tries to eat the dog?

-Four masked people broke in through the front door of this Atlanta home. The couple and their children complied. Three thieves took valuables upstairs while the adults and one of their children were held in the basement. The husband attacked the robber when the robber put his hands on his wife and pulled her clothes down. The homeowner said, “I realized he wasn’t holding the gun firmly. He wasn’t holding it strong. So I was waiting for a time when I could attack.” During the fight the gun went off and shot the robber in the leg. The gunman ran out through the front door but stoppedNew Jersey. The Franklin Revolver and Rifle Association held its 26th Women & Guns class. 23 women came to learn firearms safety and practice with handguns. The club provided volunteer coaches, range safety, and the use of the shooting range. Ammunition, targets and refreshments were paid for by a grant from the NRA.

Franklin Borough native and National Pistol Champion John Heller gave a one-hour lecture on firearms safety and basic pistol marksmanship. Each student shot 60 rounds during the half day event. Dawn Siek of Stockholm, New Jersey won top honors in the electronic illuminated red dot sighting category by scoring 95 and 97 out of a possible 100 points. Her coach for the day was Mark Jenkins

In the open sights classification, Virginia Tomala of Wantage earned “top


Personal news from each participant

Rob- I took some training at a local gunshop Thursday night. We reviewed presentation from concealment. I recorded the end of class summary with the instructor. I wrote it down when I got home. Now I’ve got homework when I dry practice! I also cleaned my 45 magazines, and cleaned the 22 I use with new students. I was impressed. That little gun will run when it is very dirty.

John – Did some dry practice with my SIRT pistol. Had snow on Saturday morning but still went out to a gun auction on Saturday night to see if I could pick something up cheap. Not enough people showed up so they turned it into a silent auction.

Break
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Seg 2- News

-A few years ago, Marycar and crashed a short distance away. He was found dead with his pistol in his hand. Police are calling the shooting justified and have no plans to charge Mr. Lummus. They did, however, refer the incident to a grand jury.

–Four thugs tried to break into a Jacksonville, Florida home around 1:45 AM on Friday. The homeowner was armed with a rifle and shot one of the suspects multiple times causing them all to flee. Shortly thereafter, a car pulled up to UF Health Center with the injured suspect. Police took all four into custody. They don’t expect to bring any charges against the homeowner who was uninjured.

– This next example of armed self-defense was sent to us by one of our listeners in Houston. Thank you, Scott!

There


Dublin Street Pub where they got into an argument. They returned to the hotel around midnight where the argument escalated. Deputy Chan shot Deputy Martin in the back as Martin fled toward an elevator. The wounded deputy was taken to local hospital and pronounced dead. Officer Martin was married and had three children under the age of 10. A spokesman for the sheriff’s department said deputies are allowed to drink alcohol as long as they are not on duty, but they are held to a code of conduct.

BREAK

-A voter in Douglasville, Georgia was told to remove his hat before being allowed to vote. A poll worker complained because the hat said “NRA Instructor” which the poll worker associated with the Republican party. Bundy Cobb, who is certified byknow for example MONEY!
Quarter, Nickels, Dimes, those are very helpful
when it comes to math and then we apply it
back to our questions.
Be sure to join me in the next video where
I take you through multiplication and division
tricks showing you the decimal trick that
I applied here and so much more!
Are you stuck on a specific MCAT topic? I
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contaminant posing health hazards to humans and animals even when present at low levels.
The accumulation of lead shot also represents an unrealized economic resource. When the accumulation of shot is great enough, the contaminated bottoms might be more efficiently mined than other sources of lead found in nature, if a suitable recovery device existed. Reclamation of the lead shot from the lake bottom could, therefore, reduce environmental stress associated with other lead mining operations that are needed without the lead shot recovery.
While various mineral recovery devices are known in the art for recovering items such as gold particles, nuggets or flakes from a slurry of feed material, these devices typically are not designed to recover uniformly sized particles. Furthermore, most recovery devices known in the art cannot operateThe invention relates to a device according to for the individual adjustment of the intensity of several spectral lamps.
Absorption spectrometers, in particular, frequently contain several spectral lamps for the generation of measuring radiation which is suitable for the sample to be investigated in each case. When the lamps are activated individually in sequence, their respective operating parameters can be regulated, in a simple fashion, directly by means of the central power unit, as a function of a measurable variable derived from the measuring ray path. However, if all the lamps are activated simultaneously and combined into a common measuring ray bundle with the aid of reflecting mirrors, several regulators, arranged after the common power unit, are required for individual adjustment of the operating parameters of the individual lamps.


Tuesday, September 8

When we bought this house first on my list was to rip up the carpet and see what was in store...4 layers of paint and hundreds (maybe thousands) of staples later laid beautiful pine treads all in great shape! A lot of sweat, stripping and sanding later here is a newly refurbished pine staircase. The treads were stained with a dark mahagony finish, same as the railing. Our wood worker (Jason from One Stop Wood Shop) removed the rail and post and finished that in his shop. The risers were replaced with textured paintable wall paper - beautiful and durable and was only $40 for 2 rolls! I've had people question the wall paper but with 4 animals (1 rambuncous puppy) and not one rip itsplayed just 14 game snaps, yet is the only NFL player with three sacks. That's three more that Clay Matthews and Julius Peppers have combined.

"Then they started calling me by name and calling me 'Sackmaster,'" Elliott said. "So it's just fun to joke around with Clay and Pep, because you know Peppers never really talks to anybody, so it's fun to hear him talk."

Not only did Matthews talk to Elliott, he talked about him on Monday.

"I heard he's starting this weekend in front of me," Matthews joked.

That won't happen this week, when the Packers likely will play their defensive starters for at least the first half of Friday's preseason game against the Oakland Raiders. But it could happen in the preseason finale against the Kansas City Chiefs on


Eruption of the nevado del ruiz volcano, Colombia, on 13 november 1985: gas flux and fluid geochemistry.
The 13 November 1985 eruption of Nevado del Ruiz volcano, in Colombia, released a small volume of pyroclastic material and a disproportionately large volume of volcanic gas. Before the eruption, summit fumarole gases became less water-rich, and the sulfur/chlorine ratio increased. Remote measurements of sulfur dioxide flux after the eruption indicated active degassing at levels associated with eruptive or inter-eruptive stages of other volcanoes. Thermal water analyses revealed increases in magnesium, calcium, and potassium and an increase in the magnesium/chlorine ratio, suggesting that these elements may have been leached from new magma. Ash leachate data showed sulfate and chloride concentrations and ratios that would be expected for the late stages ofa major43. Let m be i(25). Let j(h) = m*w(h) + 3*r(h). Give j(-6).
-1
Suppose -3*p - 28*o + 46 = -33*o, 2*p + 5*o - 39 = 0. Let x(h) be the first derivative of 1/3*h**3 + 1/2*h**2 - p - 4*h. What is x(0)?
-4
Let b be (2/(-3))/((-4)/(-36)). Let r(n) = -4*n - 3. Let x(f) = -4*f + 7. Let l(s) = s - 2. Let y(i) = 7*l(i) + 2*x(i). Let o(z) = r(z) - 5*y(z). Give o(b).
-9
Let z(b) = 5*b + 6*b**2 + b - 2 + 1 + b**3. Let s(j) = -j**2 - j + 3. Let u(c) = -6*c**2 - 33*c - 55. Let p(x) = 5*s(x) - u(x). Let a be p(-25). Give z(a).
-6
Let h be (-3 + 42/15)*-5. Let o be


with characters, it’s only natural to think of them as having lives of their own—lives that exist in some parallel universe, and go on even when we’re not tuning in. We may receive text messages or alerts when something significant has happened during the course of a character’s day, or we may get “breaking news” alerts pushed to our smartphones when an important battle has been won.

Storytelling Goes Bottom-Up

People have been putting their own material on the Web for a long time now, but new business models have been slow to evolve. Big studios and production companies are just beginning to take audience participation seriously—such as with Syfy’s hybrid game/TV show Defiance.

Creators will continue to find elegant ways to incorporate audience ideas and participation into professional-quality programming andDebû, France; Dr. Shinsuke Fujioka, Japan; Dr. Anhar Hassan, USA; Dr. Mark Hirsch, USA; Dr. Ioannis Isaias, Germany; Dr. Janis Miyasaki, USA; Dr. Rajesh Pahwa, USA; Dr. Owen Ross, USA), and we herewith express our sincere gratitude for their work.

We do hope to see the posters and hear the oral presentations belonging to these abstracts, and to discuss their content with the presenters, colleagues, and distinguished IAPRD congress faculty, during the **upcoming IAPRD XXVI World Congress on Parkinson\'s Disease and Related Disorders, on 1**--**4 May 2021 in Maastricht, The Netherlands**.

Authors who wish to re-submit to the 2021 congress an abstract that is published here are encouraged to do so; however, the same abstract, or a slightly modified abstract of the same study, will not be published again in


and Other Movement DisordersA 414 - A 435Rehabilitation, Nursing/Physiotherapy, Other Allied Health; Patient ParticipationA 436 - A 451 Image 1

Fig. 1. **Countries of origin of abstract submissions**. Light blue: 1--5 abstracts; blue: 6--20 abstracts; dark blue: more than 20 abstracts. Image created with mapchart.net© (CC BY-SA 4.0).

[^1]: Chair, Abstract Review Committee, IAPRD 2020.

[^2]: Chair, Scientific Program Executive Committee, IAPRD 2020.
Q:

What are interesting cases of ATC agreements between countries?

I'm doing some research about cooperative documents between nations regarding ATC; does anybody can mention interesting cases of agreements across the globe? Relations such as Swiss/Others and Hong Kong/China (during British domain) comes to my mind. Also, is there known, famous cases of events (incidents/accidents) caused by disagreement between ATC of different countries you could mention?

A:

You could look into the situation regarding the airspace above northern Cyprus. This relates to 'disagreements', rather than 'agreements'!
Cyprus was invaded by Turkey in 1974, and since then the country has been split into two sections with a UN 'buffer-zone' between the two. The northern portion of Cyprus is not recognised as a separate country (well, not recognised by many States ...), and whenever 'Cyprus'


flights generally ignore that instruction, and contact Nicosia ATC directly.
Heading in the opposite direction flights are told (by Nicosia ATC) to contact Turkish ATC, completely ignoring Ercan Control.
In practise, there are extremely few flights flying these routes, so the problem rarely arises. The use of Ercan Control is limited to Turkish flights heading from Turkey to northern Cyprus.
See Cyprus ATC

and all funds raised will be used to provide vital services and programmes to the Australian community.

The Executive Centre was once again proud to be the Gold sponsor of the Experience Gala Charity Ball 2015, organised by the Canadian Chamber of Commerce in Hong Kong on May 23 at the Grand Hyatt Hotel.

The Executive Centre is pleased to have been honoured as “Caring Company” by Shenzhen Autism Society, a registered non-profit organisation dedicated to conducting research on the autistic children’s psychology, behaviour and education. The award is in recognition of the Company’s launch of “Care for the Autistic Children” initiative from 28 March to 2 April 2015 in China to bring public awareness on the autistic children and their families. The award presentation ceremony was held at Shenzhen


digital letters must be balanced against
the historic value of having such records available for further students of
history, so to speak.

But it just occurred to me that a system like looking glass could easily
accommodate both: have the system automatically archive a copy of incoming and
outgoing email, both encrypted to the (gpg-)key belong to the system owner.
Such a system might retain "cryptological" plausible deny-ability (the owner,
having the key, could fabricate a fake archive) -- but it would probably loose
any "legal" equivalent. (eg: anyone can fake their browser history log files,
but they're still used as evidence etc).

It would be easy to automate what should be archived, and it would also remain
possible to shred certain things from the archive, if wanted. It might even be
possible to store an archive in a git-like   dd if=/dev/disk6 of=disk.bin
 *
 * To produce an ".iso" file with 2048-byte sectors, we must eliminate the extra “junk” (eg, sync
 * and address bits, headers, error correction, etc) from each sector in the ".bin" file.
 *
 * We do this by extracting each 2352-byte sector from bufferBin, discarding the first 16 and the
 * last 288 bytes, and writing a 2048-byte sector out.
 *
 * It probably goes without saying that if the ".bin" file is from anything other than a simple data
 * CD-ROM with a single track of data, the resulting ".iso" will likely be unusable.  One warning
 * sign that something is amiss is if the ".bin" file doesn't contain a perfect multiple of 2352-byte
 * sectors.
 *
 * Note


    bufferBin.copy(bufferSector, 0, iBuffer, iBuffer + cbSector);
        streamISO.write(bufferSector);
        cbTotal += cbSector;
    }
    streamISO.on('finish', function() {
        printf("%d bytes written\n", cbTotal);
        process.exit(0);
    });
    streamISO.end();
}

if (args.argc < 3) {
    printf("usage: node bin2iso [input file] [output file] [options]\n");
} else {
    let argv = args.argv;
    convertBinToISO(argv[1], argv[2], argv['debug'], argv['overwrite'], argv['verbose']);
}
groups.

….and a lot more.

Architecture

The basic principles of this implementation are as follows:

Etcd members will reside in private subnets and accessed via an internal load-balancer.

Etcd members will be joined to a cluster by leveraging the Etcd discovery URL.

A bastion host will be used to proxy all access to the private subnets.

The Terraform script creates all the components, at the VPC level and beyond.

The scripts are separated into the following files:

. ├── deployetcd.tpl ├── etcdBootstrapScript.tf ├── etcdEC2Instances.tf ├── etcdMain.tf ├── etcdNetworking.tf ├── etcdSecurityGroups.tf ├── etcdVPC.tf ├── terraformec2.pem ├── terraform.tfstate └── terraform.tfstate.backup

deployEtcd.tpl

This is a template file for Terraform, it’s used to generate a bootstrap script to run on each of our Etcd nodes.

To begin with, download Etcd, extract and do some general housekeeping with regards to access and users. It will


     return "../icons/" + d.type + ".png";
                    }
                })
                .attr("x", -25)
                .attr("y", -25)
                .attr("width", 50)
                .attr("height", 50);
                         console.log("before",node);
                if (!superNodeShown){
                        node.style("visibility", function(d) {

                        if (d.id =="supernode") return "visible";
                        else return "hidden";