samples of plasma sEVs (*N* = 42) and the corresponding unfractionated plasma paired-aliquot (*N* = 42) to assess expression levels of 1,305 targets encompassing a diverse set of molecular functions, including cancer \[[@B23-cancers-12-01147],[@B26-cancers-12-01147],[@B27-cancers-12-01147]\].

The distribution of proteins among LUAD and PDAC cases and controls in plasma-derived sEVs and unfractionated plasmas as analyzed by aptamer array is summarized in [Figure S3](#app1-cancers-12-01147){ref-type="app"}. Classifier performances of individual proteins analyzed in the respective compartments were calculated using T test and Receiver Operating Characteristic (ROC) area under the curve (AUC) values to evaluate capacity for distinguishing cases from matched controls. The LUAD and PDAC cohorts were analyzed separately and also as a combined, pan-adenocarcinoma case cohort. A total of 108 and 397 proteins were identified in plasma-derived sEVs that yielded statistically significant (2-sided Wilcoxonis a glycoprotein modulator of Wnt-signaling that has been observed to play both tumor suppressor and oncogenic roles in a number of human cancers and to also be subject to epigenetic regulation via DNA methylation or microRNA transcriptional silencing \[[@B44-cancers-12-01147]\]. A recent study demonstrated functional relevance of exosome-associated SFRP family proteins and that human lung cancer cells take up SFRP-containing exosomes, whereby SFRPs co-localize with β-catenin in both the cytoplasm and nucleus to mediate β-catenin/TCF-mediated transcription of Wnt target genes known to effect cancer stem cell properties \[[@B45-cancers-12-01147]\]. B2M (Beta-2-microglobulin) is a component of the class I major histocompatibility complex (MHC-I) and is a crucial factor required for MHC-I assembly and maintenance of stable surface presentation of antigens to immune system effectors \[[@B46-cancers-12-01147]\]. We previously found MHCs and


of tumor-derived EVs from uninformative, circulating background populations. Herein, we have identified cancer-associated EV-protein features that may offer utility for early interception of disease. Our findings provide a basis for inclusion of identified EV-resident protein targets on validation studies that encompass other biomarker candidates \[[@B51-cancers-12-01147],[@B53-cancers-12-01147],[@B54-cancers-12-01147]\].

4. Materials and Methods {#sec4-cancers-12-01147}
========================

4.1. Blood Samples {#sec4dot1-cancers-12-01147}
------------------

Whole blood samples were collected at MD Anderson Cancer Center (MDACC) through informed consent following institutional review board (IRB) approval (PA14-0552). Healthy control samples were obtained from volunteers in the clinic waiting rooms and for the most part, are relatives of the patients. Plasma was prepared from EDTA-treated whole blood by two successive room temperature centrifugation steps for 12 min at 1200× *g*, without braking and subsequently stored in −80 °C until use.

4.2. Exosome Isolation {#sec4dot2-cancers-12-01147}
----------------------

Cell linethe pellet for an overnight washing step, again at 100,000× *g*. The resultant sEV pellet was resuspended in PBS and harvested for further analyses.

For the isolation of plasma sEVs we applied a density gradient flotation approach. Cell debris and large EVs were depleted by centrifugation at 2000× *g* for 20 min followed by 16,500× *g* for 30 min; the resulting supernatant was additionally filtered through a pre-wetted 0.22 µm vacuum filter (Steriflip SCGP00525, MilliporeSigma, Burlington, MA, USA). The lEV-depleted plasma was mixed with OptiPrep iodixanol solution (MilliporeSigma, St. Louis, MO, USA) to a final density of 1.18 g/mL. This was loaded into the bottom of a polycarbonate ultracentrifuge tube (Seton Scientific Inc., Petaluma, CA, USA) and overlaid with 2--3 mL of 1.14 g/mL iodixanol/PBS (phosphate buffered saline) solution


Q:

Problem in installing Ubuntu 12 using USB

I have a Sony laptop (VPCEH25EN) and i am trying to install Ubuntu 12.04 LTS. I downloaded the iso named "ubuntu-12.04-desktop-amd64.iso". For installing i created a bootable USB using UltraISO.
When i booted the USB it hangs and shows " Booting from USB ", I even left it for hours and it didn't moved a bit. When I booted the ISO in Virtual Box, it ran well.
I even used other tools to make a bootable USB, then it says " BOOTMNGR missing ".
Please help, I am new to Ubuntu and my optical drive is fried.
Thanks in advance..

A:

Try creating the bootable USB using UnetBootIn.
My experience with this program is excellent.
Otherwise if you have another Ubuntu computer you may try "Startup Disk Creator"

has been in direct contact with both the Cayman Islands government and the UK government, urging them to finally work together to ensure that this government-owned facility transitions into a true turtle sanctuary. Unfortunately, these calls have been repeatedly sidestepped and ignored.

Now the Farm has yet again proved that it represents a severe threat to the health of both its turtles and tourists alike. The burning question now is how much disease and dishonesty will it take for them to instigate real change at this farcical facility?


FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
// AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
// LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
// OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN
// THE SOFTWARE.

using System;
using System.Linq;
using MonoDevelop.Core;
using System.Collections.Generic;
using MonoDevelop.Projects.Text;

namespace MonoDevelop.Ide.TextEditing
{

	public class LineCountEventArgs : TextFileEventArgs
	{
		int lineNumber;
		int lineCount;
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		{
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		public override string ToString ()
		{
			return String.Format ("[LineCountEventArgs: LineNumber={0}, LineCount={1}, Column={2}]", lineNumber, lineCount, column);
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	}}
create an instance of Class2. Your Params object of Class1 needs to be initialized like so:
var model = new Class1
{
    Id = Convert.ToInt32(reader["ID"]),
    Name = reader["Name"].ToString(),
};
model.Params = new Class2();
model.Params.Param1 = "param1";

A:

Because when you use Class2. you're referencing the class itself, not an instance of the class.
You have to either declare Class2 as static or, in your case, create an instance of it:
private Class1 GetData(SqlDataReader reader)
{
    var model = new Class1
    {
        Id = Convert.ToInt32(reader["ID"]),
        Name = reader["Name"].ToString(),
        Params = new Class2 { Param1 = "foo", Param2 = "bar", Param3 = "other" }


pattern recognition and area measurement applications. The video inspection system of the present invention is small, powerful, fast, relatively inexpensive and very reliable.
In an illustrative embodiment the present invention is employed in a quality control application to compare labels on bottles coming off a high speed fill line with a reference label to determine whether the bottles bear the correct labels and whether the copy on the labels has been smudged or otherwise damaged. In a preferred mode of operation the difference, if any, between the reference label and the label being inspected is displayed on a TV monitor for viewing by an operator. The advantages of this application are readily apparent since now it is possible to have 100% quality control inspection without incurring large labor expenditures.
In\mathbb{N} | n=4m+7k \geq 18   ~~~ m,k \in \mathbb{N} \}$ is infinite.
so: $\{1...17\}$ is finite set. QED.
I am not sure about this proof because it seems "specific" about $n-4$, and what about $n-3$?
I would appreciate your help!

A:

This follows from the Chinese Remainder Theorem, but here is a cool way that I like to teach younger children of realizing this fact. Suppose we have a number $n = 4m_1 + 7k_1$. Note that if $k_1 \geq 1$, then we can immediately conclude that $n + 1$ is expressible as $4m + 7k$, as we can "exchange" one of the sevens for two fours, thereby constructing $n + 1$. That is $n + 1 = 4(m_1 + 2) + 7(k_1 - 1)$.
With


Yardbarker: Sun-Woo Kimhttp://www.yardbarker.com/mlb/players/sun_woo_kim/349
Recent articles about Sun-Woo Kimen-usKATOH Projects: Seattle Mariners ProspectsPrevious editions: Arizona / Baltimore / Boston / Chicago AL / Chicago NL / Cincinnati / Cleveland / Colorado / Detroit / Houston / Kansas City / Los Angeles (AL) / Los Angeles (NL) / Miami / Milwaukee / Minnesota / New York (AL) / New York (NL) / Philadelphia / Pittsburgh / San Diego / San Francisco.
Last week, lead prospect analyst Dan Farnsworth published his excellently in-depth prospect list for the Seattle Mariners. In this companion piece, I look at that same Seattle farm system through the lens of my recently refined KATOH projection system. The Mariners have the 24th-best farm system in baseball according to KATOH.
There’s way more to prospect evaluation than just the stats, soand his walk rate is significantly worse than average. If you didn’t know any better, you might look at Owens’ 2015 stat line and conclude that he’s a fringe prospect.
Owens’ 2015 numbers may not be much to look at, but he performed 04 Aug 2015 14:00:40 -0400http://network.yardbarker.com/mlb/article_external/henry_owens_to_debut_in_boston/s1_8637_19288324
http://network.yardbarker.com/mlb/article_external/henry_owens_to_debut_in_boston/s1_8637_19288324Henry Owens to Debut in Bostonhttp://www.yardbarker.com/mlb/articles/henry_owens_to_debut_in_boston/s1_8637_19288324http://www.yardbarker.com/images/yb_logo_square_grey.pngSouth Korea beats Iraq for under-19 crownSouth Korea came from a goal down to beat Iraq in a penalty shootout and claim its 12th under-19 Asian title on Saturday.
Iraq, looking for its first title since the war-torn country won the 2007 Asian Cup, stuck first in the 35th minute when Mohanad Abdulraheem took a pass in the area and scored from close range in the United Arab Emirates.
But just when Iraq was preparing to celebrate, South Korea


I could watch you sleep
Hold you body closer, breathe you deep
And everything feels broken
When you're not next to me(exactly what it says ) ( they are not together because of everything)
Would you still be you
If we weren't we ( would she be the way she is with anyone else.) would? Could she be happy with another ) would she let her guards down for another )

Under your scars I pray
You're like a shooting star in the rain
You're everything that feels like home to me, yeah
Under your scars, I could live inside you time after time
If you'd only let me live inside your mind

So hey, if you feel like coming down
If you feel like coming around
Just call my name out loud, na, na, na
Hey, if you feel like comingMissions & Ministry Guide – Free Download

Missions and Ministry Guide is a listing of the missions, ministries, and state missionaries for the Georgia Baptist Convention. This is a Free downloadable guide that you can view or print from your computer (PDF 14.4 mb).

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Our Church Plans is a 19-month planning guide and calendar (PDF 9.8 mb) with listings of GBC and SBC events and special dates. The Free download includes extra planning pages not currently included in the printed Our Church Plans.

Great Commission Budgeting Guide

This resource will help move your church to a budget process that is more sensitive to the basic teaching of Scripture and helps a church evaluate its ministries in light of the Great Commission.*FREE to GBC Churches (see description)

Our Church


Ohio, who is emerging as a rare exemplar of measured opposition to Mr Trump. Mr Sessions, he said, “is a former colleague and a friend, but I think it would be best for him and for the country to recuse himself” from the relevant probes.

Mr Trump was having none of that. Asked on March 2nd whether he stood behind Mr Sessions, whose strong antipathy to illegal immigration made him an early passenger on the Trump train, the president said he had “total” confidence in him. He also said Mr Sessions had “probably” told the truth in his Senate confirmation hearing and should not recuse himself from any investigation.

A couple of hours later, at a press conference called to address the scandal, Mr Sessions said he had recused himselfQ:

select distinct(date) return the same date several time

On my Oracle database, I have a table with a column with Date as data type.
When I do this :
select distinct(MY_DATE) from MY_TABLE where extract(year from MY_DATE) = 2014;

I get this :

And when I do this query :
select MY_DATE from MY_TABLE where extract(year from MY_DATE) = 2014;

That's what I have :

I guess it's because of the different seconds and milliseconds.
How to ignore the time in date to have only one result in my fisrt query ?

A:

Try the Query below, which just adds TRUNC() to your date column before taking a DISTINCT of it.
select distinct(TRUNC(MY_DATE)) from MY_TABLE where extract(year from MY_DATE) = 2014;

This is because the time factor in your column data is not the same.
TRUNC() will nullify the time element, retaining


the date only
The query will actually reveal it. TO_CHAR() to output the date saved in the format specified.
select TO_CHAR(MY_DATE,'MM-DD-YYYY HH24:MI:SS') from MY_TABLE where extract(year from MY_DATE) = 2014;

More about TRUNC from Oracle Docs

Adelaide United recruit James Troisi says the moves involving himself and Melbourne Victory coach Marco Kurz will add more fuel to the A-League rivalry between the two clubs.

Socceroos midfielder Troisi moved across from Victory last month and Melbourne swooped on Kurz to replace Kevin Muscat, after the German coach's contract wasn't renewed by Adelaide.

The two teams clash at Coopers Stadium on Saturday in what Troisi rated as probably the biggest home game of the season for United.

With no other South Australian A-League club, Troisi said the match against Victory was Adelaide's equivalent of a derby given the great rivalry and history between the two clubs.

"I guess this one (on Saturday) is a little bit more enhanced because Marco has gone to Victory and I've come to Adelaide, so


racial fixations, we may soon have to undergo computer scans of our skin colors to rank competing claims of grievance.”

For 200 years, European-American immigrants and the generations that followed were united behind constitutional republicanism. But with the social and cultural entropy of the 1960s, that unity began to disintegrate. In recent decades, ethnocentric divisions have emerged, and, most notably, those divisions have become significant politically manufactured obstacles to the integration of immigrants coming to America.

In 1991, I acquired a copy of Arthur Schlesinger’s book, The Disuniting of America, now a benchmark classic on ethnocentric divisions. As a distinguished Harvard professor and former senior advisor to JFK, Schlesinger condemned the orthodoxy of self-interested hyphenated-Americanism — those who, rather than unifying to become one, were diversifying to become many. Hemade.

"Ho Ching and I deny these allegations, especially the absurd claim that I have political ambitions for my son."

His response says the statement from his younger brother and sister "has hurt our father's legacy," and that he would "continue serving Singaporeans honestly" to the best of his ability.

The prime minister said he would address the issue more fully on his return.

Fears of repercussions

Lee's siblings, in their statement, also claimed Hsien Yang will be leaving Singapore as they feared "the use of state organs" against them and Hsien Yang's wife.

"Singapore is and remains my country," Hsien Yang said in the joint statement. "I have no desire to leave. Hsien Loong is the only reason for my departure."

It is the second time in as many years that the family has


Q:

OnClickListener cannot be resolved to a type (Eclipse)

Hello im new to programming, im trying to construct my first simple application, im looking to play a short soundclip on the push of an ImageButton.
while typing out my code i get an error with the statement;
 Button.setOnClickListener(new OnClickListener() {

The on click listener is underlined and when i go to the error eclipse tells me that OnClickListener cannot be resolved to a type.
Here is my code:
import android.app.Activity;
import android.os.Bundle;
import android.view.view;
import android.view.view.OnClickListener;
import android.widget.Button;
import android.widget.ImageButton;

public class main extends Activity {
/** Called when the activity is first created. */
@Override
public void onCreate(Bundle savedInstanceState) {
    super.onCreate(savedInstanceState);
    setContentView(R.layout.main);

final ImageButton Button = (ImageButton) findViewById(R.id.imageButton1);
Button.setOnClickListener(new OnClickListener() {
    public void onClick(View v) {
        // Performexpression. In contrast, ATF3 depletion resulted in cell growth reduction and p21 transcriptional upregulation. More importantly, ATF3 overexpression partially antagonized TSA-induced growth inhibition and p21 activation. Collectively, these data demonstrate that ATF3 acts as an essential negative regulator of TSA-induced cell growth inhibition through interfering with TSA-induced p21 activation.


Q:

What does "get through their brains" mean?

I can't seem to get through their thick brains.

Get through someone means: to succeed in talking to someone on the phone, but what does "get through their brain" means? Is it an idiom derived from the idiom "get through someone"? I am a little confused on where the expression comes from, and what it means exactly. Could you explain what "get through someone" can mean, and then tell us what "get through their brains" mean?

A:

It is a fairly rude way of saying

I can't get them to understand me.

It would be slightly more common as "get through their thick skulls". It says that "I can't get information into their brains".
Calling someone "thick" or saying that they have a "thick skull" or "thick brain"[Changes in the affinity of oxygen for hemoglobin during general anesthesia].
The well known effects of the lowering of the intraerythrocyte 2, 3, diphosphoglycerate (2, 3, DPG) level and hypothermia, on the affinity of oxygen for hemoglobin, lead the authors to study the influence of these parameters on this affinity during general anesthesia. The following observations were made in 15 adult subjects, undergoing prolonged general anaesthesia (average time: 3 hrs. 10 minutes): the dissociation curve of oxyhemoglobin (DCO) by the method of mixing, the intraerythrocyte 2,3, DPG level, the hemoglobin concentration and arterial blood parameters (PO2, PCO2, pH). These measurements were recorded before and after the general anaesthesia. The results were the following: a significant reduction of P50, measured under standard conditions (from 27.64 +/- 1.74 torr to 25.57


King's Food Bank

Main menu

There are several donation points where non-perishable food items can be taken including some supermarkets where items can be purchased. These are:

Asda, Kendal

Booths, Kendal

Morrisons, Kendal

Cumbria County Council, County Offices, Kendal

Kendal Library

Nat West Bank, Kendal

SLDC South Lakeland House, Kendal

Wilf’s Café, Staveley

and local Churches

Monthly Update

During these difficult weeks, we have been extremely busy at the Food Bank with an increase in referrals for families and individuals who find themselves in crisis situations. So far this year up to the end of April we have received over 500 referrals and supplied 10,600 meals. We are overwhelmed by the generosity of so many individuals, businesses, and societies, who have donated so abundantly, both financially and with items of food, we would not be able to help so many peoplesame call. Perhaps what you're seeing is the OpenCL runtime waiting for one of the multiprocessors to free up. This relates most directly to the occupancy issue - if the work size can't keep the multiprocessor busy, through memory latencies and all, it has idle cycles. The limit here depends on how many registers (local or private memory) your kernel requires. In summary, you want to write your kernel to operate on multiple pieces of data more so than queueing it many times.
Did your measurement include reading back results from the apparently fast executions?


what Russia is doing with the properties. Once the US agrees to list them as diplomatic posts they become inviolable,” continued Assange, who in a subsequent online discussion argued the “US has a right to expel any diplomat. Not property.”

It doesn't matter what Russia is doing with the properties. Once the U.S. agrees to list them as diplomatic posts they become inviolable. — Julian Assange 🔹 (@JulianAssange) September 2, 2017

“The govt signed the treaty. It can demonstrate that its signature is worth nothing but that will affect all past and future agreements,” surmised Assange.

Moscow similarly flagged up the Vienna Convention, the foundation document of post-war diplomatic relations, when it said the US had plans to search the Washington trade mission building and the San Francisco consulate, “including theAfter an investigation, Local 38 concluded that Tripodi was the responsible party. On October 5, 1994, at a hearing *292 before the Executive Council of Local 38 (the "Hearing"), Tripodi was charged with violating seven provisions of the Union Constitution. After the Hearing, the Executive Council issued a fine of $3,000 per violation, or a total of $21,000. Defendant has neither paid nor appealed this fine. Local 38 brought the instant action to collect the $21,000 fine assessed at the Hearing.
Defendant's principal argument is that he was no longer a member of Local 38 at the time of the alleged violations and at the time of the Hearing. He argues that the Executive Committee and Local 38 thus lacked the power to issue a fine against him. He


argues in the alternative that, even assuming that he technically was a member of Local 38, plaintiff still may not fine him for operating a sheet metal business without a Union Agreement because he was given leave to do so.
At trial, Local 38 presented three witnesses and introduced various documents into evidence. The crux of its case is as follows:
1) In August 1994, defendant Tripodi performed sheet metal work at two locations without first receiving a "withdrawal card" from Local 38. At the time, Tripodi was a member of Local 38 and a signatory to the Union Constitution which provided, inter alia, that
Good standing members who become owners, partners, agents, contractors, or subcontractors ... of a sheet metal shop or business ... shall be eligible to receive andEstrogen replacement therapy. Universal remedy for the postmenopausal woman?
The menopausal woman is in a state of estrogen deficiency that induces a variety of metabolic, structural, and symptomatic disturbances. Indications for estrogen replacement therapy include vasomotor symptoms, psychosomatic complaints, urogenital atrophy, prevention of osteoporosis, and prevention of coronary heart disease. Potential risks of therapy include development of endometrial and breast cancer. The incidence of both can be decreased with combination estrogen-progestin therapy. Future research efforts should be directed toward identifying the postmenopausal woman at increased risk for osteoporosis and/or coronary heart disease.


[@B24]; Sun et al., [@B102]; Takayanagi et al., [@B104], [@B105]; Ardekani et al., [@B3]), functional-based (Georgopoulos et al., [@B57]; Calhoun et al., [@B21]; Demirci et al., [@B37]; Michael et al., [@B78]; Arribas et al., [@B4]; Shen et al., [@B96]; Castro et al., [@B25]) or combination of structural and functional features (Fan et al., [@B45]; Ford et al., [@B49]).

In recent years, spontaneous modulation of blood oxygenation level-dependent (BOLD) signal during the resting condition has found fruitful clinical applications (Fox and Greicius, [@B51]). Resting-state fMRI (rfMRI) experiments are less prone to multi-site variability, allow a wider range of patients to be scanned and make it possible to study multiple cortical systems from one dataset (Fox and Greicius, [@B51]). Moreover, more accurate connectivity maps can be detected using rfMRI data comparedGarrity et al., [@B55]). In the seed-based approach, individual seed voxels from predefined brain regions of interest (ROI) are chosen and the cross correlation of other voxels\' time courses (TCs) with the selected seeds then computed, to derive a correlation map. This map can then be thresholded to identify voxels showing significant FC with the seed voxels.

An alternative approach is based on ICA, a multivariate data-driven method which as a blind source separation method, can recover a set of signals from their linear mixtures and has yielded fruitful results with fMRI data (Calhoun et al., [@B19]; Calhoun and Adali, [@B15]). ICA estimates maximally independent components using independence measures based on higher-order statistics. Compared to general linear model approaches, ICA requires no specific temporal model (task-based design matrix), making


and paradigm description
-------------------------------------

One session of resting-state fMRI data was collected from 28 healthy and 28 schizophrenic patients. Participants gave written, informed, Hartford hospital and Yale IRB approved consent at the Institute of Living and were compensated for their participation. Schizophrenia was diagnosed according to the DSM-IV TR criteria on the basis of a structured clinical interview (SCID) (First et al., [@B48]) administered by a research nurse and review of the medical file. Exclusion criteria included any participants with auditory or visual impairment, mental retardation (full scale IQ \< 70), traumatic brain injury with loss of consciousness greater than 15 min, presence or history of any central neurological illness and a positive urine pregnancy test. Participants were also excluded if they met criteria for alcohol or drug dependence within10 × 10 × 10 mm^3^ FWHM Gaussian kernel was performed.

### Group ICA and back reconstruction

Prior to the ICA, data dimensionality was reduced at two levels using principal component analysis (PCA). First at the subject level, dimensionality was reduced to 80. Then reduced data from all subjects and all sessions were concatenated together and put through another reduction step. The number of components for the second level reduction was estimated to be 20 by minimum description length (MDL) criterion (Li et al., [@B71]). This is also the number of IC components. Note the MDL is a data driven approach, so it is not dependent on whether data are collected at rest or during a task.

Infomax group sICA (Calhoun et al., [@B16]) was conducted to decompose the aggregated data


be considered as simple feed forward ANN (Rosenblatt, [@B93]). First the input vector is transformed using a non-linear transformation to give a feature vector. The algorithm then tries to change the weight vector of the neural network using gradient stochastic descent algorithm to minimize the error in an iterative manner. At each iteration, the weight vector of the network is manipulated by perceptron learning rule. The perceptron convergence theorem guarantees that the perceptron learning algorithm can find the solution in finite number of steps if such a solution (data is linearly separable) exists (Block et al., [@B9]).

*Linear support vector machine (SVM)*. Over the last 15 years following the work by Cortes et al. (Cortes and Vapnik, [@B31]), SVM has proven useful in many machine learning and pattern recognitionthe Results section.

*Non-linear support vector machine*. By using the kernel trick, SVM can map the not-linearly separable data into a higher dimensional space where the samples are hopefully lineally separable. This mapping to higher dimensional space is difficult, but since SVM formulation depends on the inner product of each of training samples with the support vectors, the kernel is defined as this inner product so the problem is solved in the same fashion as the linear case. There are many kernel functions but the most widely used ones are Gaussian radial basis function (RBF) and polynomial kernel. There is at least one parameter in a kernel (except for the linear kernel) which should be optimized along with the soft margin usually by grid search over reasonable values of


    35.2        22.3           (45, 40, −10)
  R inferior parietal lobule      40           16.6        27.3           (45, −62, 39)
  R inferior frontal gyrus        44, 45       28.1        19.5           (48, 40, −12)
  R superior frontal gyrus        6, 8, 9  a lot to be thankful for this weekend because both the Eat-Clean Diet and the Eat-Clean Diet Cookbook have been great successes.

I am happy to announce the Eat-Clean Diet Cookbook was #1 in its first week!

This is all because of you!! Thank you so much for supporting me and believing in me. All I want to do is share my passion for a healthy lifestyle with you and motivate you to do the same!

Keep up the good work and remember to Eat Clean for health and for life!

Tuesday, October 2, 2007

What a great weekend in Miami. The Hotel Victor was fantastic and the JNL crew put together a wonderful event. I had an excellent time interacting with 30 wonderful women who gave it their all at the High


Scaling of MOS transistors, which has been a driving force for the semiconductor industry for more than 40 years, is now becoming more and more difficult to execute. One possible solution for continuing the trend of performance increase of MOS transistors is to replace the silicon channel by other semiconductors, such as Ge or III-V. However, although having superior transport properties compared to Si, III-V materials based devices seem to have more severe short channel effects and leakage currents than in the case of silicon technology. It is therefore necessary to rigorously evaluate the intrinsic performance of these devices. This work presents a theoretical evaluation of the performance of MOSFET devices based on III-V materials and demonstrates that higher dielectric constants and lower effective masses of these materials /**
     *
The name of the error.

     */
    inline NamespaceInfoV2& WithName(const Aws::String& value) { SetName(value); return *this;}

    /**
     *
The name of the error.

     */
    inline NamespaceInfoV2& WithName(Aws::String&& value) { SetName(std::move(value)); return *this;}

    /**
     *
The name of the error.

     */
    inline NamespaceInfoV2& WithName(const char* value) { SetName(value); return *this;}

    /**
     *
The namespace ARN.

     */
    inline const Aws::String& GetArn() const{ return m_arn; }

    /**
     *
The


SetIdentityStore(const IdentityStore& value) { m_identityStoreHasBeenSet = true; m_identityStore = value; }

    /**
     *
The identity store used for the namespace.

     */
    inline void SetIdentityStore(IdentityStore&& value) { m_identityStoreHasBeenSet = true; m_identityStore = std::move(value); }

    /**
     *
The identity store used for the namespace.

     */
    inline NamespaceInfoV2& WithIdentityStore(const IdentityStore& value) { SetIdentityStore(value); return *this;}

    /**
     *
The identity store used for the namespace.

     */
    inline NamespaceInfoV2& WithIdentityStore(IdentityStore&& value) { SetIdentityStore(std::move(value)); return *this;}

    /**
     *
An error that occurred when the namespaceKarzai praise Afghan forces for foiling deadly Kabul attack

Afghan president Hamid Karzai praised Afghan security forces for their bravery and speedy action to control the situation and kill a group of suicide bombers who attacked the Afghan spy agency on Wednesday.

Six suicide bombers launched a coordinated attack on Afghanistan’s spy agency in Kabul on Wednesday, killing two people and wounding 30 others.

The attack started at around noon when a suicide attacker detonated a large car bomb near a gate of one of the National Directorate of Security’s (NDS) buildings.

Afghan presidential palace following a statement said Afghan security forces shot dead the remaining suicide bombers who were looking to detonate their explosives and kill further innocent Afghans.

In a statement released on their propaganda website, Voice of Jihad, the Taliban


Ishaan Tharoor reviews Trump’s Riyadh speech:

But let’s be clear about what the speech really was: A sop, soaked in platitudes, to the Saudi agenda in the Middle East.

Trump’s embrace of the Saudis and their agenda is in keeping with his general enthusiasm for our most authoritarian clients and allies, and the speech was a statement of his administration’s Iran obsession and what passes for conventional wisdom in Washington regarding relations with our clients in the region. According to the latter view, Obama was insufficiently supportive of U.S. clients in the region and too open to accommodating Iran, and so Trump has made a point of proving how different he is from Obama by subordinating U.S. policy in the region to the preferences of Riyadh. Where Obama was shamefullya handful--all that's needed is a Slack group and video calling tools.

"It is easy," says Gregorio Rojas, head instructor of Sabio, a Southern California-based coding bootcamp. Earlier this year, Sabio received approval from the California Bureau for Private Postsecondary Education. "It is easy even for people with no coding experience. Someone with a technical background could produce a very credible online presence in no more than a day."

There are several bootcamps that have proved their worth as respectable institutions. Schools like Hack Reactor, Thinkful, Wyncode, and Turing School, for example, regularly publish their student outcomes as a way to be transparent and build trust with prospective students and the public. Other schools--Flatiron School, MakerSquare, Epicodus, and Zip Code Wilmington--have launched partnerships with established universities in conjunction with the


U.S. Department of Education.

Collectively, however, coding boot camps have struggled with self-regulating. Last year, many top schools tried forming a trade association with the goal of creating universally accepted standards for outcome reports, which can include stats such as job placements, program completion rates, and average salaries. But ultimately, the organization fell apart, with bootcamps saying they disagreed over standards. Several top schools also initially failed to deliver on a promise to President Obama to report outcomes audited by third parties.

Since then, more schools have begun reporting outcomes and increasing transparency about what portion of their students graduate, get jobs, the types of jobs they land, how much they pay, and how long it takes to find those jobs. But generally speaking, lack of regulation makes it easywhat is called a “production cushion” by its ability to quickly pump additional oil (around 2 million bpd) to balance abrupt global oil shortages. Pari passu, instability in the Saudi state infuses a higher risk premium into the oil price, which otherwise would not be necessary. The bravado positioning by the Saudis or the Iranians, the “I can bomb the hell out of you” cant may not all be to waste because it injects additional dollars into the oil price. The Saudis and Iranians can sell the oil, but neither Iran nor definitely Saudi Arabia command history. The Saudis and the Iranians cannot bear serious influence on the strategic character of oil. Ultimate control of oil is in the remit of the imperialist power and or the way


time span relative to the historically determined living standards and life expectancies. Technological progress under capitalism improves the war-related technology, and involuntarily, the means for the prolongation of life. Growth of technology, war technology and war are market processes alienated from social control under capitalism.

War,as a domain of accumulation, is the shortest route to premature life extinguishing and, therefore, the furnace of surplus value making. People are value. They are the labourers and the stock of labour power at once. People are not cheap, they are consumed as existing value and de-commissioned by a history of imperialist slaughter. This is quite different from the conventional notion of military Keynesianism, which measures monetary form, as opposed, to the value content of war.

China, in particular, bore tremendous losses at theguys into which socialism will appear from nowhere. His was the real intercausal world dominated by belligerent imperialism opposed by weak anti-systemic liberation movements whose fights are shaped by cultural identities infused with class consciousness. This was an anti-dogmatic position in which not only and not always were Soviet-allied communist parties internationalist.

Just as capital counteracts its own homogenising forces via identity politics or labour differentiation, labour through the exercise of its “particularity”, through national liberation movements, re-universalises the condition of production for labour and bridges global living standards. Capital integrates the world market, but as the less developed must become similar in level of development (homogenisation), it bludgeons them into inferior status (differentiation). By shifting the focus in the struggle on class as opposed to identity and, equivalently,


its own objective and alien market forces. It unavoidably must stop China. The case may be that it is only the reasonable view of some US strategists who foresee the prospects of any nuclear disaster as mutually assured destruction or a nuclear winter, which mitigates the realisation of that abominable first strike scenario (Johnstone, 2017).

The market imbroglio

With the nuclear confrontation’s prospect being serious but remote, China’s market-led expansion remains vulnerable so far as its trade routes fall in areas of US sponsored or instigated wars or through states under the thumb of Uncle Sam, like the Gulf states. More to the point, China’s energy security and circuits are vulnerable. The recent coup by the defiant Saudi prince potentially destabilises that circuit in a region that exports a fifthcapacity and financial wherewithal to withstand the shock and possibly use the opportunity to recapitalise with alternative energy sources. China is also adopting measures to avert an energy sparked crisis. Already, China invests in electric vehicles, renewables, and its own shale and coal reserves, which will reduce the country’s dependence on foreign suppliers (Butler, 2017).[23] Moreover, higher oil prices incentivise regions that produce at high cost, shale and tar sands, to join the chorus of oil producers. With so much additional oil production and state credit available, wither the window of opportunity by which a Saudi-US instigated oil shock can trigger a financial bust in China.For imperialism, neither the first-strike nor the market-strike windows of opportunity are viable options.

China is the world’s leading auto-sufficient system of market accumulation,


of US imperial twilight. The US had tried in vain to enact a no-fly zone over Syria, but was faced with by the Chinese and Russian veto. More recently, the US’s attempts to sacrifice the Kurds in Iraq have failed. Such concrete events as manifestations of many chance occurrences signal an opportunity to be appreciated, a novel historical necessity, the rise of the developing world behind the new big wall of China.

The US’s Saudi sponsored coup, a fratricidal spectacle torn from the pages of a Shakespearian play, will most likely flounder because manic MBS has confronted public power (the Leninist class-based understanding of the deep state as an instrument of capital), the bureaucratic structure and the order of kinship and clientelism holding together the kingdom. The coup willto the definition of MBS as an incontrovertible war-asset to imperialism. The extolled NY Times reformer, is more than just a custodian of the oil spigots on behalf of empire. War and oil politics are complex and inseparable. MBS combines more of both than his predecessors.

History is against the US/Saudi alliance

There are other sociological reasons that might hasten the failure of the coup. The US held Saudi Arabia in a state of animated suspension to control/usurp its oil, it imposed upon that society an immutable state of consciousness re-enacted by a fabricated Islamic conservatism; such stasis, in which the European colonial settlement of Palestine remained unforgiven, would backfire if the gung-ho prince was to allegorically hoist the Zionist flag over Mecca. Saudi life before oil was of the


region. Such legacies instilled at the popular level are the brakes that will hold back impetuous pro-Zionist-imperialist rapprochement.

Of course, the imperialist sponsored Sunni-Shiite identity schism reared by the invasion of Iraq and its US-erected Sectarian constitution is a sinkhole into which Iran had fallen, othering many into the Sunni hand-me-down imperialist rubric (The Bremer constitution for Iraq). But the recent gains of the multi-sectarian Arab Syrian army and the bitter victory of Yemen, a country that withstands a baleful famine in the process, had thrown a monkey wrench into the imperialist plot. The blowback from the defeat of the MBS-Zionist alliance/coup will air on the side of China. What China had sown into the Arab world, especially its long-standing support for the rights of the Palestinian people, willservices have an interest in such a topic. https://thediplomat.com/2017/11/what-the-saudi-shake-up-means-for-china/

[15] There are many strands within the Saudi ruling circles. The “what is in it for me bunch” are, as the term implies, the sections of the royal family and associates who seek a higher share of the rent for themselves, but are also unwilling to sacrifice the whole social formation in the process. There are also those with sentiments of distrust toward US policies that have emerged from the extension of Iranian power to Iraq.

[16] OPEC sees evidence of oil market moving to balance.

http://www.channelnewsasia.com/news/business/opec-sees-evidence-of-oil-market-moving-to-balance-9403148

[17] China’s ‘Best And Brightest’ Leaving U.S. Universities And Returning Home

https://www.forbes.com/sites/kenrapoza/2017/04/17/chinas-best-and-brightest-leaving-u-s-universities-and-returning-home/#43d121751d41

[18] The Comintern is an abbreviation of the Communist International,

https://www.marxists.org/history/international/comintern/

[19] For portentous or propaganda reasons, there are many articles that flaunt American nuclear primacy as an


option with China. The Rand’s study by Gompert, David C., Astrid Stuth Cevallos and Cristina L. Garafola entitled,War with China: Thinking Through the Unthinkable. Santa Monica, CA: RAND Corporation, 2016, https://www.rand.org/pubs/research_reports/RR1140.html, is one such example.

[20] Keck Z. (2015) “The Most Dangerous Nuclear Weapon in America’s Arsenal”, The National Interest,

http://nationalinterest.org/blog/the-buzz/the-most-dangerous-nuclear-weapon-americas-arsenal-13433

[21] In unusual criticism, Tillerson slams Russia’s ‘malicious tactics’ ahead of trip to Europe.http://www.latimes.com/nation/la-fg-tillerson-russia-20171128-story.html

[22] Chossudovsky M (2017) Imagine What Would Happen if China Decided to Impose Economic Sanctions on the USA? Global Research, September 03, 2017

[23] Butler N (2017) Made in China – the world energy market of the future, Financial Times,

https://www.ft.com/content/c1ddb6e1-b9df-39f9-bcd5-ee97989928b3

[24] Avoiding war: Containment, Competition, and Cooperation in US-China Relations, Brookings,

https://www.brookings.edu/wp-content/uploads/2017/11/fp_20171121_china_interview.pdf

[25] Ai S. (1965) Surreptitious Substitution of Theory of Reconciliation of Contradictions and Classes for Revolutionary Dialectics Must NotIntroduction {#Sec1}
============

Hematocrit (Hct), the volume percentage of red blood cells (RBCs) in total blood, and hemoglobin (Hb) are associated with a risk of cardiovascular disease. A high Hct level has been shown to be associated with an increased risk of cardiovascular disease^[@CR1]--[@CR3]^. On the other hand, J- or U-shaped relations between Hct and morbidity and mortality from cardiovascular events have been shown^[@CR1]^. The relationship between a low Hct level and cardiovascular disease is controversial^[@CR1],[@CR3],[@CR4]^. It is well known that Hct and Hb levels are major determinants of blood viscosity and oxygen delivery dynamics. It is thought that changes in blood viscosity and oxygen delivery dynamics alter vascular function and structure. Indeed, Lee et al. showed that high blood viscosity was associated with increased carotid intima-media thickness (IMT)^[@CR5]^. However,


a quadratic function gives a better fit. Peak Hct of 46.64% was calculated by the delta method. Peak Hct was used to determine the Hct range of 46.0--48.9% at which NID was the highest among the six groups, and the Hct range of 46.0--48.9% was used as the reference group in the multiple logistic regression analysis. Similar reverse U-shaped relations were found between Hb and NID and RBCs and NID. The peaks of Hb and RBCs were used to determine the ranges of 16.0--16.9 g/dL for Hb and 5.00--5.39 × 10^6^/μL for RBCs at which NID values were the highest among the six groups, and the ranges of 16.0--16.9 g/dL for Hb and 5.00--5.39 × 10^6^/μL for RBCs were used as reference groups in the multiple logistic regression analysis. Age, body mass index (BMI),with all authors. S.K., Y.H. contributed to the writing of the manuscript. Y.K. and K.C. revised the article critically for important intellectual content. All authors contributed to interpretation of date and review of the manuscript, and approved this manuscript for submission.

The authors declare no competing interests.


Q:

Custom XMPP IQ in iOS XMPP Framework

I want to send custom IQ using xmpp framework in iOS for the following XML:
<iq type="get">
<questionrequest xmlns="xyz" group="abc">
</questionrequest>
</iq>

I used the below code in iOS:
XMPPIQ *iq = [[XMPPIQ alloc] initWithType:@"get"];
DDXMLElement *query = [DDXMLElement elementWithName:@"questionrequest" xmlns:@"xyz" group:@"abc"];
[iq addChild:query];
[[[self appDelegate] xmppStream] sendElement:iq];
NSLog(@"iq: %@", [iq prettyXMLString]);

It is giving an error when I add group="abc"> part in DDXMLElement *query. Please help.

A:

it worked by using the below code:
XMPPIQ *iq = [[XMPPIQ alloc] initWithType:@"get"];
    DDXMLElement *query = [DDXMLElement elementWithName:@"questionrequest" xmlns:@"naseebprofile"];
    [query addAttributeWithName:@"group" stringValue:@"Tastes"];
    [iq addChild:query];
    [[[self appDelegate] xmppStream] sendElement:iq];

comprising; a movable assembly mechanism to act on a workpiece received from the first assembly station; and a drive train between the movable assembly mechanism and the main drive mechanism for driving the assembly mechanism in response to rotation of the main drive mechanism; wherein the first assembly station is movable with respect to the second assembly station in a direction parallel to the main drive mechanism central longitudinal axis between a plurality of positions, each position of the first assembly station being at a different spacing from the second assembly station to vary the distance between the assembly stations.

Full Text

APPARATUS, KIT AND METHOD FOR ROLLER CHAIN ASSEMBLY
FIELD OF THE INVENTION
The present invention relates to the assembly of products requiring multiple assembly stations. More particularly, the present invention


the bushings 24 to assemble a complete roller link. The assembler 10 could also comprise a roller chain assembler apparatus, with the first station 12 comprising a pin link assembly station for pressing pins 26 into holes in a pin link plate 22, the second assembly station 14 comprising a roller link assembly station for placing a complete roller link on the adjacent pins 26 of adjacent pin link plates 22, and the third assembly station 16 could comprise a coverplate assembly station for pressing the covering pin linkplate 22 to complete the roller chain.
The illustrated assembler apparatus 10 includes a main drive mechanism 40 having a central longitudinal axis 42- The main drive mechanism 40 is rotatable about its central longitudinal axis 42, and is driven byindexes to pull the chain or partial assemblies from the second assembly station 14 to the third assembly station 16, after the second assembly station movable assembly mechanism 54 has operated on the chain workpieces, and after the third assembly station movable assembly mechanism 54 has operated on the chain workpiece, from the third assembly station 16 to a storage area.
Each locator unit 84 workpiece support 150 functions to provide a substantially continuous horizontal support for the workpieces between the ram 82 of each assembly station 12, 14, 16 and for the complete chain to the sprocket 180. As shown in FIGS. 7-9, in some assembly stations, the workpiece support 150 may also provide vertical supports or walls 181 to define an undercut channel 179 through which a


bottom plate, such as a roller or pin link plate 20, 22 with upstanding pins 26 or bushings 24 maintained uprights by the vertical supports 181 assure proper positioning of partial or complete assembly of workpieces as it travels from one assembly station to the next. A continuous horizontal suppon 183 may [ie beneath the vertical supports 181, as shown in FIGS. 7-9.
It should be understood that the shape of the support 150 will depend on the use of he apparatus. For example, it may be desirable to have such vertical supports 181 and indercuts along a substantial length of me apparatus, particularly if the apparatus is being

used to assemble a roiler link component for later assembly into a completed chain. For such an apparatus, the sprocket 180be provided for any one or all of the locator units 84 of FIG. 2 or FIG. 7. More than one set of alternate locator units may also be provided, depending on the variety of products to be made with the assembler. Each of the bridges 152 and workpiece supply lines 154 may also be removable and interchangeable with alternate structures that may be provided with a kit.
In the method of the present invention, roller chain products of different pitch may be made on a common assembly system apparatus 10. The method comprises the steps of

providing First, second and third assembly stations 12, 14, 16. Each assembly station includes an assembly mechanism 54 and a drive train 56 for driving the assembly mechanism. A main drive mechanism 40


were stopped on the frontier of the Wadai Empire, Sultan Yusuf proving firm in his adherence to the Senussi teachings.

Muhammed al-Mahdi's growing fame made the Ottoman regime uneasy and drew unwelcome attention. In most of Tripoli and Benghazi his authority was greater than that of the Ottoman governors. In 1889 the sheik was visited at Jaghbub by the pasha of Benghazi accompanied by Ottoman troops. This event showed the sheik the possibility of danger and led him to move his headquarters to Jof in the oases of Kufra in 1894, a place sufficiently remote to secure him from a sudden attack.

By this time a new danger to Senussi territories had arisen from the French colonial empire, who were advancing from the French Congo towards the western and southernThe 15 most bizarre video game Collector’s Editions and... wait, one of them is $10 million? Really?

A collector’s edition usually represents a great opportunity to nab yourself some official, bespoke merchandise to truly solidify your love for a franchise, character or universe. They’re never cheap, but what else are you supposed to line your trophy cabinet with other than the mini fridges, superhero masks and RC cars that come packaged within these vintage bundles of gaming goodness?

That said, not every collector’s edition has been worth the investment, with the following examples representing an ill-fated selection of overpriced, poorly conceived, and weirdly designed products that probably should have never left the drawing board.

Dead Island: Riptide Zombie Bait Edition (2013)

RRP: £99.99

This one is bound to go down in the annals


edition.

Despite arriving in the form of a Blu-ray disc, however, the film runs in bog standard definition, with stereophonic audio quality to match. Ironically, the fact that it’s still a Blu-ray disc means that Xbox 360 owners are treated to nothing more than a brief making-of DVD about the game itself.

Looking for the next great game to add to your collection? Check out our list of the best new games of 2018.      return (int)Math.Floor(Math.Log(_count, (1.0 + Math.Sqrt(5)) / 2.0)) + 1;
    }

    class Node
    {
        public TKey Key;
        public TValue Value;
        public Node Parent;
        public List<Node> Children = new List<Node>();
        public bool Mark;

        public void AddChild(Node child)
        {
            child.Parent = this;
            Children.Add(child);


     {
            child.Parent = null;
            // TODO: shouldn't _count be updated?? Same in Consolidate();
            Root.Add(child);
        }
        Root.Remove(result);
        if (Root.Count == 0)
        {
            Min = null;
        } else
        {
          that I got to go through it and I don’t think it is fair that not everyone gets the opportunity to go through it.”

“I cannot give you the pin,” DeGeneres said. “But what I can do, I know you want to go to college, … so Shutterfly is giving you a check for $20,000.”

Watch:

Andresen had recently completed the final requirements to earn his Eagle Award, including his final project of building a “tolerance wall” at his former middle school to show victims of bullying that they are not alone.

“I went through a lot of bullying in my life,” he said.

After his troop denied him the Eagle Scout award, his mother started a petition October 2 on Change.org demanding that Boy Scout officials reconsider their decision. Within two days


{#sec:stop_less_lyot_coronagraph}
==========================

Interest of the SLLC {#sec:interest_sllc}
--------------------

Pupil apodization suppresses the diffraction pattern of the telescope by concentrating most of the energy of the PSF inside a central peak rather than inside the Airy rings. The use of a focal plane opaque mask is, however, still required as an antisaturation and stray-light control device. As long as this mask fully covers the central peak of the apodized PSF, diffraction at the mask edge will be minimal, keeping the Lyot stop from being imperative. In the following, we use the term stop-less Lyot coronagraph (SLLC), previously introduced by @ndiaye2007 [@ndiaye2008], to refer to the combination of such a pupil apodization and a focal plane mask.

In the IFS mode of FRIDA, the forthcoming spectro-imager for the adaptive optics system of the *Gran Telescopiodifferent central obscuration stop sizes and an outer pupil stop with a size of 92% of the entrance pupil diameter as in the SPHERE/IRDIS LSS mode to mostly eliminate the diffraction due to the focal plane mask. The contrasts in the presence of a centrally obstructed pupil stop prove larger than in the case of a clear pupil stop, underlining the interest in the inner stop for removing the diffraction due to the entrance pupil obscuration. Additional tests showed little impact of the inner stop size on the overall coronagraphic performance for values beyond 20%, which remained larger than the 14% entrance obscuration diameter. A common intensity level of $7.7 \times 10^{-5}$ is reached at 0.25, which proves to be higher than the SLLC value and thus shows


IRDIS), and the photon noise. Thermal background from the instrument ($\sim$340 photon sec$^{-1}$ pixel$^{-1}$) and sky are also included. The sky is modeled by a constant emission below 2 [$\mu$m]{}and a black body at longer wavelengths [@lena1998]. The emission values are calculated to match the typical sky brightness in the near-IR provided by ESO[^1] ($J$ = 16.5, $H$ = 14.4, $K_{\mathrm{s}}$ = 13.0). The temporal evolution of the OH lines is not considered in these simulations.

![image](fig10){width="100.00000%"}

Observations representing one hour of total exposure time are created that combine various stars and planets. The stars are G0, K0 and M0 at 10 pc, simulated using standard Kurucz models [@kurucz1979; @castelli2003]. The planets cover a wide range of effective temperatures ([T$_{e\!f\!f}$]{}= 400–2000 K) and surface gravity ([log *g*]{}= 3.5–5.0) values. They are simulated using the BT-SETTL10 library[^2]of the average contrast difference between a G0 star at 10 pc and all the simulated planets in the data. The $1\sigma$ error bars are obtained by introducing each fake planet in the five independent data sets, at two symmetric positions on either side of the star (e.g. +0.4and -0.4, see Fig. \[fig:example\_data\]), resulting in ten measurements for each planet.

As explained in the previous section, a smaller restoration factor denotes an extracted spectrum of better quality. From Fig. \[fig:restoration\_contrast\] it clearly appears that the ALSC offers a significantly better restoration of the spectra at small angular separation. The effect is the most significant at 0.3, and slowly decreases up to 0.75where the restoration factors have identical values for both coronagraphs. The cutoff of the extreme AO system occurs at $\sim$0.5and $\sim$1.2at


13 and injuring 145. It was a 40-year-old bridge, and quite obviously there were hidden weaknesses that went undetected until it was too late. Sad to say, it can also happen to Christians. When I spoke at a seminary this past year, one of the professors came up to me and said something like, “Bob, I’m so encouraged to see men like you who are still faithfully proclaiming God’s Word.”

This started me to thinking. It was as though this professor was indicating that a number of seminary students do not persevere. A fellow-graduate and I were discussing this not long ago, and he proceeded to list a number of men in his class at seminary who had failed to persevere. I am aware of some who have deniedAnd second, “What is meant by the expression ‘drift away’?” We have several possible answers to the question, “Who is the author referring to when he says ‘we’?

1. The “we” refers to Jewish unbelievers who have heard the gospel, but have not really embraced it for salvation.

2. The “we” refers to believers.

3. The “we” refers to the members of a particular church, a few of whom might be unsaved.

The first view is held by John MacArthur, who writes:

“To whom is the warning directed? It cannot be to Christians. They can never be in danger of neglecting salvation – in the sense of not receiving it – since they already have it. They can neglect growth and discipleship, but they cannot neglect salvation. Nor can the warning be to


confidence firm until the end (Hebrews 3:12-14, emphasis mine).

These are “brothers and sisters.” The danger is “becoming hardened by sin’s deception.” And the solution is not “repent and be saved,” but “exhort one another each day.” It sounds to me like the author is speaking to believers.

11 On this topic we have much to say and it is difficult to explain, since you have become sluggish in hearing. 12 For though you should in fact be teachers by this time, you need someone to teach you the beginning elements of God’s utterances. You have gone back to needing milk, not solid food. 13 For everyone who lives on milk is inexperienced in the message of righteousness, because he is an infant. 14 But solid food is for theno friction, no dramatic sense of departure. But when the winds of trouble come, the things of Christ are left far behind, even out of sight. The writer of Revelation uses different language, but refers to the same thing when he says to the ostensibly healthy Ephesian church, ‘Yet I hold this against you: You have forsaken your first love’ (Revelation 2:4).”7

So, the danger is that Christians may grow cold in their love for Christ, drift from their dependence upon the nourishment of His Word, and by this neglect, put themselves in danger. The nature of that danger will now be addressed in the verses which follow.

The Consequences of Drifting

2 For if the message spoken through angels proved to be so firm that every violation or disobedience received


salvation, we are drifting.

2. My awareness of the nearness of God has become ancient history. If the intimacy I once knew and enjoyed is now a faint memory, I am drifting.

3. My love and desire for God’s Word falls short of what I find in Psalm 119.

4. The realities of heaven and hell seem distant and unreal.

5. I fall apart at the first sign of suffering or persecution.

6. I am unaware of the constant, downward pull of the world, the flesh, and the devil.

7. Prayer, Bible study, witnessing, and going to church are a duty, rather than a delight.

8. The Lord’s Table is dull, and preaching is boring.

9. Remembering the work of Jesus Christ on the cross does not emotionally move me.

10. I become autonomous, rather than deeplyNEW ENGLISH TRANSLATION, also known as THE NET BIBLE, is a completely new translation of the Bible, not a revision or an update of a previous English version. It was completed by more than twenty biblical scholars who worked directly from the best currently available Hebrew, Aramaic, and Greek texts. The translation project originally started as an attempt to provide an electronic version of a modern translation for electronic distribution over the Internet and on CD (compact disk). Anyone anywhere in the world with an Internet connection will be able to use and print out the NET Bible without cost for personal study. In addition, anyone who wants to share the Bible with others can print unlimited copies and give them away free to others. It is available


this is a transient effect provoked by the photoperiod extension, it is also possible that the previous study in sheep underestimated effects on maximal levels of expression for technical reasons. We therefore favour the view that extended light exposure on the light-inducible elements of the SCN clockwork leads to heightened cycle mean levels of *Per1-2* gene expression. This explanation probably also accounts for the LP-induced doubling of 24-h cycle mean expression for *Fbxl21* observed in the present study.

In contrast to *Per1*/*Per2* and *Fbxl21*, exposure to LP blunted the peak to trough amplitude of the *Bmal1* daily rhythm. Such changes in daily amplitude of clock gene expression were not observed between SP-adapted vs LP-adapted sheep \[[@pone.0159201.ref036]\]. Indeed, although photoperiodic differences in phasing and duration of clock gene expression areeffect of light have been reported: in rat, *Vip* mRNA and protein exhibit clear daily rhythms with high levels during the night and decreasing levels concomitant with lights-on (references in \[[@pone.0159201.ref062]\]; contrastingly, *Vip* mRNA is not rhythmic in the golden hamster \[[@pone.0159201.ref066]\], only a weak oscillation is observed in the Siberian hamster \[[@pone.0159201.ref067]\] and no variations of immunoreactivity are found within the human SCN \[[@pone.0159201.ref068]\]. Likewise, no large variations in mRNA levels are found in the mouse or the diurnal rodents *Arvicanthis ansorgei* and *Arvicanthis niloticus* exposed to a light-dark cycle \[[@pone.0159201.ref062],[@pone.0159201.ref069]\]. These differences suggest that rhythmic *Vip* expression is not a prerequisite for SCN function across mammals.

Interestingly, we did not detect *Grp* mRNA within the ovine SCN. This might be relevant since *Grp*-expressing cells of the rodent


from the other mammalian species, ranged from 59.9% to 89.5%, and 52.9% to 77.3%, and from 61.1% to 93.2%, and 58.7% to 88.4%, respectively. Phylogenetic analysis based on both nucleic and amino acid sequences showed that the beluga whale IL-2 was closely related to that of the ruminant species, which includes the bovine, while the grey seal IL-2 was closely related to that of the canine.the 4.6-kb COX-2 mRNA, only site I is present in the shorter 2.8-kb isoform. HuR in MDA-MB-231 cell extracts associated with COX-2 mRNA at the identified sites. Further, HuR location in the cytoplasm was induced by serum withdrawal, a stimulus known to induce COX-2 mRNA. Down-regulation of HuR by two independent methods, namely RNA interference as well as antisense RNA expression, significantly attenuated serum withdrawal-induced increase in COX-2 mRNA (both the 4.6- and 2.8-kb isoforms) and protein levels. These data suggest that HuR binding to COX-2 is critical for its post-transcriptional mRNA stabilization.


2017 Chevrolet Niva Review, Engine, Release Date, Price and Photos

New generation of the Chevy’s crossover Niva was presented at most current car show in Moscow. Nevertheless, production model really should arrive as 2017 Chevrolet Niva. As it was presented in Russia, SUV will be launched there through next year. Comparing to current model, this vehicle is significantly improved, in particular on performance end by boosting its 4×4 system. Street tests are on the way and first photos of new vehicle have arrived. Although it was heavily covered.

2017 Chevrolet Niva Engine

Current model of the crossover gets its power kind 1.7-l petrol drivetrain with direct fuel injection. New 2017 Chevrolet Niva may have 1.8-l four-banger PSA powertrain installed under its hood. Manual transmission will likely be applied again, with 5a case.

Case Description
================

In 1991, a 2-day-old newborn male with simple TGA, normal coronary artery pattern (1L-2RCx), and an intermediate position of the great arteries (aortic root to pulmonary root between anterior--posterior and side-by-side position) underwent the arterial switch operation using spiral anastomoses of the great arteries and a pantaloon patch of untreated autologous pericardium to fill the coronary button holes and to extend the short main PA for 1.0 cm ([Fig. 1](#FI160227crc-1){ref-type="fig"}). In 2012, the patient underwent invasive catheterization showing a mild pulmonary stenosis (i.e., maximum gradient of 20 mm Hg) with normal function of semilunar valves. In 2015, a 3D model of his heart was developed out of polyurethane according to phase-contrast cardiac MRI data ([Fig. 2](#FI160227crc-2){ref-type="fig"}: MR voxel size 1.12 × 1.11 × 7 mm; [Fig. 3](#FI160227crc-3){ref-type="fig"}: 3D model pixel size 0.66 × 0.66 mm,


Q:

Highcharts static line with background color below it

I need a "minimum" style line that is spread across value y and is static at it. What I have so far:
yAxis: {
    plotLines: [{
        color: 'red',
        width: 2,
        value: <?=$product[0]['current_price']?>
    }]
}

Now what I want to do, is take the background below this line, and color it. How do I achieve that?

A:

Unfortunately background under plotLine is not supported. You can only use Renderer http://api.highcharts.com/highcharts#Renderer and add extra shape, or use plotBand, below plotLine.
http://api.highcharts.com/highcharts#xAxis.plotBands

Stokes, who was trying to complete his second run, and deflected towards the boundary. The umpires awarded the home team six runs. Also Read - IPL 2020 News: MS Dhoni on Ambati Rayudu's Return, Slams CSK Batsmen And Bowlers For Inconsistent Performances vs Delhi Capitals

But, the replay showed that when Guptill threw the ball Stokes and Adil Rashid, the non-striker batsman, had not crossed each other thus they should have been awarded five and not six runs. The extra one run went on to decide the champions of the World Cup as the match ended in a tie, resulting in Super Over from where England won. Also Read - CSK vs DC IPL 2020 Match Report: Prithvi Shaw, Kagiso Rabada Shine as Delhi Capitals Inflict 44-run Defeat on


 5,832,802     4,964,887      31.81
  Duplicate                     534                       549,426,400   5,494,264     4,720,781      32.81

######

Mutations observed in coding sequences (CDS) of *F*5 gene in the investigated proband and her blood relatives.

  Patient                                 Bleeding phenotype   169479974    169479975    c                t              rs970740

Hom: homozygote, Het: heterozygote, SNP: single-nucleotide polymorphism, Del: deletion, and Ins: insertion

[^1]: Academic Editors: S.-C. Chae, P. D. Cotter, A. Sazci, and C. Yapijakis


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centre this morning as the row over some of their ages continued.

Charities helping child refugees into the UK from France have called the process run by the Home Office a 'shambles'.

Beth Gardiner-Smith – from charity Citizens UK, which oversees the safe passage of young migrants into Britain – told Newsnight: 'In the camp, you've had people with megaphones, walking around calling for children to come forward and register themselves on separate lists [of UK charities seeking to help them].'

New arrivals: Child migrants covered their faces with blankets as they arrived in Britain today

Around 200 unaccompanied children with family already in the UK will be brought across the Channel by the end of the week, according to French police.

Row: Some have claimed that the refugees, who are mainly youngyears of age or over, which must be signed off by two social workers. Advertisement

Aid workers in Calais have warned the most vulnerable children face being stranded there as some adults are lying about their age to try and gain entry to Britain.

And now questions are being raised about how the children are being identified by the charities working there themselves.

Migrants and charity workers in Calais' Jungle camp admitted today the 'majority' of young migrants are 'lying' about their age to get to Britain as children because it gives them a better chance to enter the UK.

The Home Office has refused to order dental checks on the new arrivals - insisting they were 'unethical' and 'intrusive' and unless the asylum seeker appears 'significantly' over 18, they should be


Field-based and laboratory stable isotope probing surveys of the identities of both aerobic and anaerobic benzene-metabolizing microorganisms in freshwater sediment.
Laboratory incubations of coal-tar waste-contaminated sediment microbial communities under relatively controlled physiological conditions were used to interpret results of a field-based stable isotope probing (SIP) assay. Biodegradation activity of 13C-benzene was examined by GC/MS determination of net 13CO2 production and by GC headspace analysis of benzene loss. Key experimental variables were: the site of the assays (laboratory serum-bottle incubations and in situ field sediments), benzene concentration (10, 36 or 200 p.p.m. in laboratory assays), and physiological conditions (anaerobic with or without sulfate or nitrate additions versus aerobic headspace or the uncontrolled field). In anaerobic laboratory incubations of benzene at 10 p.p.m., greater than 60% of the substrate was eliminatedtheir performance and fitness (Cahill et al., [2010](#ece33794-bib-0007){ref-type="ref"}; Caldwell, Dudley, & Lilieholm, [1992](#ece33794-bib-0008){ref-type="ref"}; Chen, Koide, Eissenstat, & van der Heijden, [2018](#ece33794-bib-0011){ref-type="ref"}; Fort, Cruz, & Jouany, [2014](#ece33794-bib-0016){ref-type="ref"}; Hutchings & de Kroon, [1994](#ece33794-bib-0023){ref-type="ref"}).

Plant species vary in their degrees and types of root plasticity. Studies on the effects of soil heterogeneity on root morphology have shown that some species exhibit much stronger selective root placement than other species. The former are called "precise foragers" and the latter, which grow roots less selectively within their rooting zones, are called "scalers," and they represent two alternative strategies for root foraging (Campbell, Grime, & Mackey, [1991](#ece33794-bib-0010){ref-type="ref"}). The contrast between scale and precision of root foraging is often used to characterize rooting strategy of a plant species (Grime, [2007](#ece33794-bib-0020){ref-type="ref"}; Einsmann, Jones, Pu, & Mitchell, [1999](#ece33794-bib-0013){ref-type="ref"}; but


see Kembel, de Kroon, Cahill, & Mommer, [2008](#ece33794-bib-0027){ref-type="ref"}). Studies have shown that dominant species usually employ a low‐precision but high‐scale foraging strategy to maximize root foraging area, whereas subordinate species show greater precision (Mommer et al., [2011](#ece33794-bib-0037){ref-type="ref"}; Rajaniemi, [2007](#ece33794-bib-0043){ref-type="ref"}; Ravenek et al., [2016](#ece33794-bib-0044){ref-type="ref"}).

The growth of plants with different types of root plasticity and competitive abilities are affected by different patterns of soil heterogeneity (Hutchings, John, & Wijesinghe, [2003](#ece33794-bib-0024){ref-type="ref"}). There is evidence that more precise species are stronger competitors in heterogeneous soils (Bliss, Jones, Mitchell, & Mou, [2002](#ece33794-bib-0004){ref-type="ref"}), and species with higher physiological plasticity (i.e., more flexible resource‐uptake rates but less morphological changes) have an advantage under temporally heterogeneous soil conditions (Fransen, de Kroon, & Berendse, [2001](#ece33794-bib-0017){ref-type="ref"}). In addition, the presence and identities of competitors can also affect the rooting behavior10% P~2~O~5~, 12% K~2~O, plus micronutrients, Scotts Co., Marysville, Ohio) was applied on the surface of the patch to create a stable nutrient patch. The temporal nutrient patches were created by applying 31 ml of 24:1,000 solution made from the slow‐release fertilizer (equivalent to 0.75 g of the slow‐release fertilizer) to the nutrient patch once per week for 16 weeks. For the patches with stable nutrient or control treatments, the same amount of water was added every week when nutrient solution was applied. After 16 weeks, the granules of the slow‐release fertilizer were all empty, indicating that all nutrients had been released. In a previous study with testing pots, soil nutrient levels in variable nutrient treatments were reduced by about 75% after a week (Mou et al., [2013](#ece33794-bib-0039){ref-type="ref"}).

Combining the fertilization and competition treatments


focal plants grown in the same plot were not independent of each other, we used a linear mixed model for our analyses, with species, nutrient treatment, and competition type as fixed factors and sandbox and plot as random factor in a nested structure (plot within sandbox). Before performing the analyses, we examined if there was any influence of initial plant size on the final measurements and found no significant effects (*p *\>* *.1).

To test hypotheses 1 and 2, we compared the aboveground biomass, in‐patch fine root mass, total fine root biomass, and root/shoot (R/S) ratio of the focal plants of the two species in different treatments with linear mixed models.

The relative fine root mass difference (RFRMD), which is a measure of the ability of plants to selectively grow their roots*L. styraciflua* proliferated more fine roots than *P. taeda* in the deeper layers (Figure [3](#ece33794-fig-0003){ref-type="fig"}). When competing with *P. taeda*,*L. styraciflua* grew more roots than *P. taeda* in the third layers (160% and 200% more in stable and variable nutrient patches, respectively; Table [2](#ece33794-tbl-0002){ref-type="table-wrap"}, Figure [3](#ece33794-fig-0003){ref-type="fig"}), although the increase was only marginally significant. A similar trend was also found in the second layer (Figure [3](#ece33794-fig-0003){ref-type="fig"}). The variable nutrient treatment significantly reduced fine root mass of both species in the third layer compared to stable nutrient treatment (Table [2](#ece33794-tbl-0002){ref-type="table-wrap"}). In general, vertical root distribution patterns inside and outside the nutrient patches were similar both species across all treatments ([Figure S3](#ece33794-sup-0001){ref-type="supplementary-material"}).

![Distribution of fine root mass of focal plants by soil layers under the stable (a, b) and variable (c, d) nutrients, interspecific (a, c) and intraspecific (b, d) competition conditions. Ls,


*Liquidambar styraciflua*. Pt, *Pinus taeda*. Error bars represent ±*SE* (*n* = 6)](ECE3-8-3367-g003){#ece33794-fig-0003}

######

Analyses of effects of species (S), competition (C, inter‐ or intraspecific), and treatment (T, stable or variable nutrient) on the fine root mass in different soil layers. Data were ln transformed to obtain normal distribution and homoscedasticity of residuals. Numbers are *F* values in ANOVAs. Significant effects (*p *\<* *.1) are marked in bold

  Source            *df*   0--7 cm                                              7--14 cm   30--45% in the interspecific competition compared to intraspecific competition, but the in‐patch fine root mass of *P. taeda* remained unchanged. The total fine root mass showed a similar pattern. It is also possible that *L. styraciflua* grew bigger root system under interspecific than conspecific competition because the latter is more severe. Although the two species had similar fine root mass in the nutrient patches in conspecific competition, roots of *L. styraciflua* are thinner than that of *P. taeda* (Mou et al., [2013](#ece33794-bib-0039){ref-type="ref"}; Wang et al., [2006](#ece33794-bib-0053){ref-type="ref"}), implying that, with similar root mass, root length density of the former is higher than the latter, which is supported by our minirhizotron observations (Figure [S4](#ece33794-sup-0001){ref-type="supplementary-material"}). Root length density may be a better indicator of competitiveness than root mass (Mommer et al. ([2011](#ece33794-bib-0037){ref-type="ref"}). If this is true, thinner roots


were born between gestational weeks 27 and 38 was 1,330,822. Of these, the number of singletons, twins and triplets was 1,330,822, 90,245, and 840, respectively. A mean gestational age was 37.3±1.5 weeks, 36.0±2.0 weeks, and 33.3±2.4 weeks in the corresponding order. A mean birth weight was 3,071±490 g, 2,414±455 g, and 1,836±454 g in the corresponding order. These results indicate that gestational age and birth weight decreased depending on the plurality ([Table 1](#T1){ref-type="table"}). Mean age of mothers was 29.7 yr in cases of singletons, 30.2 yr in cases of twins and 30.5 yr in cases of triplets. These results indicate that age of mother increased significantly depending on the plurality ([Table 1](#T1){ref-type="table"}). The birth rate of triplets was increased from 0.06% in 1998 to 0.1% in 2007.

[Table 2](#T2){ref-type="table"}in our previous study ([@B12]). According to this, in the overall gestational age ranging from gestational week 27 to 38, it was relatively smaller as compared with birth weight obtained from twins and singletons ([Table 4](#T4){ref-type="table"}, [Fig. 2](#F2){ref-type="fig"}).

And we compared 50th percentile curve of Korean triplets with those of USA and Norway, it was smaller than those in the USA and Norway ([Fig. 3](#F3){ref-type="fig"}).

DISCUSSION
==========

In Korea, the birth rate has been annually decreasing. However, with the advancement of assisted reproductive techniques such as ovulation-inducing agents, the birth of multiples has been increased. With the well-trained neonatal intensive care unit personnel treating newborns and the well-equipped facility, the survival rate of premature birth has also been increased ([@B6], [@B21]).

Multiples show a higher degree of the mortality of newborns as compared


it was shown that triplets were increased by approximately two times during a 10-yr period from 1998 to 2007 in Korea. Other studies have shown that the birth rate of multiples was increased as mothers\' age was increased ([@B1], [@B4]). In Korea, it has also been shown that mean age of mothers of singletons, twins and triplets was increased. These reports suggest that the increased birth rate of triplets originated from the increased age of mothers and the development of assisted reproduction technology.

In the present study, birth weight was significantly greater in male triplets when compared with female triplets at the same gestational age. These results were in agreement with the previous reports ([@B22], [@B23]). This implies that an intrauterine growth pattern may vary genetically between male andthat can be drawn from recent ECS estimates. The most important, however, is that they do not change the big picture if all available evidence is taken into account. (...) Even the lowest ECS estimate assumed in this study only results in a delay of less than a decade in the timing of when the 2 °C threshold would be crossed when emission trends from the past 10 years are continued."

This conclusion, what we found, comes from the Supplementary Material of the paper. There, two ECS distributions, among others, were used for comparison; one was named as *IPCC AR4 consistent* and the other as *IPCC AR5 consistent*. By comparing those two, Rogelj et al. concluded that the differences of climate sensitivity 'do not change the picture'. What matters is that


and 2.5 °C, instead of the median value under the probabilistic mode assuming the probability density function. Table 1Relationship between CO~2~ eq. concentrations, emissions reductions and temperature changesCO~2~ eq Concentrations in 2100 \[ppm CO~2~ eq\] category label (concentration range)SubcategoriesCumulative CO~2~ emissions \[GtCO~2~\]Change in CO~2~ eq emissions compared to 2010Temperature change (relative to 1850--1900)2011--21002050 (%)2100 Temperature change \[°C\]Likelihood of staying below temperature level over the twenty first century1.5 °C2.0 °C3.0 °C450 (430--480)Total range630--1180−72 to −411.5--1.7 °C\
(1.0--2.8)More unlikely than likelyLikelyLikely500 (480--530)No overshoot of 530 ppm CO~2~ eq960--1430−57 to −42 1.7--1.9 °C\
(1.2--2.9)UnlikelyMore likely than notOvershoot of 530 ppm CO~2~ eq990--1550−55 to −251.8--2.0 °C\
(1.2--3.3)About as likely as not550 (530--580)No overshoot of 580 ppm CO~2~ eq1240--2240−47 to −192.0--2.2 °C\
(1.4--3.6)More unlikely than likelyOvershoot of 580 ppm CO~2~ eq1170--2100−16 to +72.1--2.3 °C\
(1.4--3.6)The above table is an extract from Table SPM.1 from AR5 WG3 that shows information including the relationship between CO~2~ eq. concentrations and temperature changes inorange line shows an emissions pathway that limits temperature increase below 2 °C over the twenty first century with a climate sensitivity of 3 °C, which corresponds to the scenario where concentration stays below 500ppmCO~2~ eq. through 2100. The red line shows an emissions pathway until 2030 on the assumption that the INDCs of countries that have been submitted by June 30 will be implemented. We estimated China's emissions will peak out in 2030 at 16.7 GtCO~2~-eq. based on its upper range of CO~2~/GDP improvement ratio of 65 % with annual GDP growth ratio of 6.2 % through 2015--2030. For the calculation of the 2030 emissions of United States, refer to the legend to Fig. [1](#Fig1){ref-type="fig"}.Fig. 1Estimated emission pathways toward 2050 by the DNE21+ model (and MAGGC model) which is a global energy system model


until 2030 based on the assumption that individual country's INDCs submitted at the end of June will be implemented. We assumed China's emissions in 2030 to be 16.7GtCO~2~-eq. This almost corresponds to its BAU emissions. The US pledge covers only until 2025 and comprises two targets, i.e., 26 and 28 % emissions reduction relative to 2005. We assumed here that the 28 % emission reduction will be implemented by 2025, thereafter with a linear interpolation to 80 % reduction in 2050. (*Source* Research Institute of Innovative Technology for the Earth)

The outcome of our model shows global total emissions under major countries' INDCs (red line) in 2030 will not be on track to attain the 2 °C target if climate sensitivity is 3 °C (orange line). On the other hand, the red line emissionsFerritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment.
Lead nitrate induces hepatocyte proliferation and subsequent apoptosis in rat livers. Iron is a constituent of heme and is also required for cell proliferation. In this study, the expression of ferritin light-chain (FTL), the major iron storage protein, was investigated in rat livers after a single intravenous injection of lead nitrate. Western blotting and immunohistochemistry revealed that FTL was increased in hepatocytes around the central veins and strongly expressed in nonparenchymal cells. Some FTL-positive nonparenchymal cells were identified as Kupffer cells that were positive for CD68. FTL-positive Kupffer cells occupied about 60% of CD68-positive cells in the periportal and perivenous areas. The relationships between FTL expression and apoptosis induction or the engulfment of apoptotic cells were examined.


Overflow': fontcolor=white: fontsize=24: box=1: boxcolor=black@0.5: boxborderw=5: x=(w-text_w)/2: y=(h-text_h)/2" /Users/user/Desktop/test.mp4

So it seems that the output portion is the part FFmpeg doesn't like in Nginx.conf
My thought is I should be passing the overlayed FFmpeg stream to the "overlay" app and have the stream published to Youtube and the frame capture from there. (And also potentially recorded).
Update: When I have tried point to a sh file to run the command rather than the direct FFmpeg exec_push I get:
[alert] 56849#0: kevent() error on 15 filter:-1 flags:4002 (2: No such file or directory)

Thanks so much!
rtmp {
server {
       listen 1935;
       chunk_size 4096;

       application live {
          Q:

How to reach the localhost of a unity game from android emulator

I'm developing a game using Unity3d and I'm facing a problem. The game which is written in C# has a database that linked using PHP (XAMMP)..
But the issue: I tried to post my Ip address instead of Localhost in c# script but still I can't connect the db,,
I used both: "http:MY_PC_IP:8080/insertuser.php";
and: "http:MY_PC_IP/insertuser.php";
I'm using Nox as an emulator..

A:

Use the internal IP address 10.0.2.2


What better place to enjoy some sex than with your boy friend on a pool table in a gorgeous house in a wonderful city on a sunny day? Nothing that’s what. The two start by playing a game of pool. Karlie Brooks looks great in her pink dress. We hope we can get a peek at that tight pristine body.

She’s smiling as he reaches his hand forth to grasp a firm titty. A cute face and a petite body equals an erection. Her sexy eyes peer into her boyfriends eyes because she knows what’s about to go down. She’s about to get fucked hard on a pool table. The two film it and sell it to the porn industry. You can’t put a price on original quality content.

KarliePolitics, Economics, Culture, and Theology with a Biblical Viewpoint

Whither the Wicker?

Guest Post by Rob Hadding

I’ve been watching politics since I was about ten. My earliest political recollections are of the 1972 Republican and Democratic conventions. I was captivated by the theater of it all. The speeches were full of pathos, the nominating process was full of drama, and it seemed like everyone was full of enthusiasm for the possibilities that lay ahead if their man (or woman – Shirley Chisholm ran that year) won the day. It all seemed so important. I’ve watched coverage of almost every political convention since, if with significantly less awe. Somewhere along the way since 1972, I began to see what every other informed observer of American politics sees. To say that I’ve


floor as a show of support and to give him a moment to rest his voice. C-SPAN 2’s existence was justified. I went to bed that night before he had finished. I said to my wife as I turned out the bedroom light, “I hope he’s still going in the morning.” But by the time the day had ended, Mr. Paul had done something that hadn’t been done in a long time – he captured the imagination of the political right, and gave them something to be excited about.

In just thirteen hours – which is a long time to stand without peeing, but not so long if you’re talking about the history of the world – a freshman senator breathed life into his party and into those ofbivalent plus a univalent, where the univalent is undergoing precocious disjunction leading to a chromosome 21 plus a chromatid in each of the daughter cells. b) Formation of a trivalent with chiasmata in an aberrant position, i.e. in this example distally within the long arm. Secondary non-disjunction at anaphase 1 will lead to two chromosomes 21 traveling into one of the daughter cells and one chromosome 21 into the other](1755-8166-1-21-4){#F4}

Materials and methods
=====================

All procedures were performed with informed consent and ethical approval from the local ethical committees. Foetal ovarian cells were obtained from eight foetuses at gestational age 14--22 weeks, following termination of pregnancy for social reasons with all the foetuses having a normal phenotypic appearance. Ovaries were removed within a few hours post-mortem and placed in L-15 (Leibovitz)


applying stringent criteria for establishing chromosome 21 copy numbers in foetal ovarian cell nuclei, we detected a proportion of T21 cells in all eight apparently normal female foetuses. Our aim was to analyse at least 1000 foetal ovarian cells in each case and this was possible in all but one of the eight cases. The average incidence of T21 cells was 0.54% with a range of 0.20--0.88% in a total cell population of 12,634 (Table [1](#T1){ref-type="table"}). There was no statistically significant difference in incidence between the eight individual cases (SD 0.23; P \> 0.05).

######

Proportion of T21 cell nuclei in foetal ovaries identified by two chromosome 21-specific probes

                 T21 cells (%) \> 0.05).

Using the same criteria as for FISH analysis of foetal ovaries we did not find any indication of a similar type of mosaicism as regards *in vitro*cultured blood lymphocytes from three children with T21 and three children with normal karyotypes by traditional metaphase analysis. Thus, in a total of 12,320 cells analyzed we did not detect any cell nucleus showing extra dual chromosome 21 signals.

Discussion
==========

Most women may be T21 ovarian mosaics
-------------------------------------

We have found that all eight ovaries obtained from foetuses, where termination of pregnancy has been performed for social reasons at gestational age 14--22 weeks, contain a proportion of cells with an extra chromosome 21. In other words these apparently normal female foetuses are ovarian mosaics with trisomy 21 in 0.20--0.88% of cells. It is tempting to


act & a symbol of #Trump's open hostility to the Iranian people.

US opposition to granting #Iran's requested facilities from @IMF to provide items needed to deal with #CoronaVirus is a real case of crimes against humanity. — علی شمخانی (@alishamkhani_ir) April 5, 2020

"Trump is more dangerous than coronavirus," Shamkhani added.

More than 3,600 people have died of COVID-19 in Iran, while the number of confirmed cases in the country reached nearly 60,000, according to Johns Hopkins University.

'We'd love to meet'

Trump on Friday said he would have a "moral responsibility" to help Iran in its fight against the coronavirus pandemic if leaders of the country asked for assistance.

"Well they haven't even asked us to do that," said Trump when asked if the United States would consider easing sanctions on IranOctober 28, Chicago - National Futures Association (NFA) has ordered IKON Global Markets, Inc. (IKON), a forex dealer member to pay a fine of $320,000 as a result of an NFA Complaint issued and a settlement offer submitted by IKON and its principal, Diwakar Jagannath.

The Complaint alleged that IKON engaged in certain price slippage practices on the MetaTrader platform that were favorable to IKON and caused disadvantageous trading conditions for certain customers. The Complaint also charged that IKON failed to supervise the MetaTrader platform used for their forex business, and failed to supervise the firm's operations.

In addition to the fine amount, IKON must provide appropriate refunds to its customers as a result of these asymmetrical slippage practices.


/*
 *   fs/cifs/smb2file.c
 *
 *   Copyright (C) International Business Machines  Corp., 2002, 2011
 *   Author(s): Steve French (sfrench@us.ibm.com),
 *              Pavel Shilovsky ((pshilovsky@samba.org) 2012
 *
 *   This library is free software; you can redistribute it and/or modify
 *   it under the terms of the GNU Lesser General Public License as published
 *   by the Free Software Foundation; either version 2.1 of the License, or
 *   (at your option) any later version.
 *
 *   This library is distributed in the hope that it will be useful,
 *   but WITHOUT ANY WARRANTY; without even the implied warranty of
 *Sending out a never ending string of follow up emails might feel a bit spammy to you, and it is. There is no magic number, or one size fits all – I tend to stop after five or six follow up’s.

With that being said, every industry and list is going to be different… it all comes down to what you’re offering. I always ask myself this: Am I trying to sell them on something they already use, or will this be new to them?

If it’s something they are already familiar with and using (some version of), that justifies a larger amount of follow up emails that are appropriately spaced out.

An example:

If I’m trying to generate leads for an architectural rendering service, I know that 90% or more of


architects are already using some type of renderings; therefore, I have no problem following up more often. The thought process is that they are already somewhat interested in my service, as they are probably already using it. I just need to get in touch with them at the right time – such as when a new project pops up that needs renderings, or their current renderer is booked and they need to look elsewhere. By continuously following up, I can stay in front of them for a month or two and hope that “perfect time” lines up close to one of my emails.

On the opposite side of the spectrum, if I’m trying to generate interest for something that will be brand new to them, I’m more likely toLimit Search To:

Rich Pellegrino Illustrations

From the brush of a RISD-trained artist still crushing it in Warwick, RPI's a wildly colorful portfolio of portraits that impose a caricature-esque aesthetic on iconic movie characters & musicians, though not ironic ones, because who wants to line their house with Juno?


valuable asset to the Patriots since entering the league.

He became the first player in NFL history to start in three Super Bowls in his first three seasons, and he's never missed a game in over his four-year career.the sampling system.

In reviewing QC data from two cities, we found that 9% and 7% of data collected were discarded due to failing to meet QC criteria. The most commonly failed QC criteria was vehicle speed, which accounted for the vast majority of discarded data. Although survey areas generally did not include high-speed roadways, the drivers often commuted from their home to the survey region via highways, and the instruments collect data whenever the car is running. Low cavity pressure, an indicator of a clogged sampling inlet, was the next most commonly failed QC criteria.

Because there is a delay in the time between when air is sampled at the front bumper and when it is analyzed by the instrument, we adjust GPS locations to account for this delay.