Purification and characterization of lysine- and arginine-specific gingivain proteases from Porphyromonas gingivalis.
Four gingivain proteases, active in presence of L-cysteine, were purified from spent culture media of oral pathogen Porphyromonas gingivalis by ion-exchange chromatography on MonoQ and chromatofocusing on MonoP columns. Three of the purified proteases, with molecular masses of 75 kDa, 70 kDa and 55 kDa, respectively, hydrolyzed synthetic chromogenic substrates with arginine in the P1 position. One protease, with a molecular mass of 80 kDa, hydrolyzed substrates with lysine in the P1 position. It is proposed these enzymes be named: arg-gingivain-75, arg-gingivain-70, arg-gingivain-55, and lys-gingivain-80, respectively, based on their molecular mass and specificity for either arginine or lysine in the P1 position. # are now in libsupc++ (not built yet).  In addition, this test has
    # cored on solaris in the past.  In addition, --gc-sections doesn't
    # really work at the moment (keeps on discarding used sections, first
    # .eh_frame and now some of the glibc sections for iconv).
    # Bzzzzt.  Thanks for playing, maybe next time.
    AC_MSG_CHECKING([for ld that supports -Wl,--gc-sections])
    AC_TRY_RUN([
     int main(void)
     {
       try { throw 1; }
       catch (...) { };
       return 0;
     }


of historical temperaments.\
    **Online Supplement:** Spreadsheet with calculations and solutions
author:
-
title: |
    Well Temperaments based on the Werckmeister definition\
    From Werckmeister, passing Vallotti, Bach and Kirnberger,\
    to Equal Temperament.\
    Inspired by Kelletat and Amiot
---

[well; circulating; temperament; interval; just; perfect; optimal; diatonic; wohltemperiert; Werckmeister]{}

“Ce qui se conçoit bien s’énonce clairement, et les mots pour le dire arrivent aisément.”[^1]

[@Boileau1674]

Issue
=====

Ever since Antiquity, temperaments are a subject of discussion. Well Temperaments (WT)[^2] emerged in the 17-th century. Many differing WT are applied, but none is universally accepted. Musical WT criteria are pretty hard to translate into comprehensive objective evaluations or classification [@Hall1973 pp. 274-290]. All this results in the fact that the choice of a musical temperamentmodel in temperament rankings (at tables \[table 8\] and \[table 9\]).

### Domain for $B=kF$, with $k=2^{10}/3^6$

Further diatonic C-major optimisation is possible substituting $B$ by $kF$, and applying the same method as in § 2.2.1. The modified partial derivatives of the sum of the modified squares formula \[equ 13\], are given in Appendix A.2 to this paper.

With F solved, altered notes can be calculated more easily, based on their perfect fifths ratio, instead of solving the formula \[equ 14\].

The domain of solutions is displayed in fig. \[fig. 6\]. The minimum impurity is obtained at ($P_{MT}=P_{mt}=0$), with a weighted diatonic purity equal to 1.778; this model is identical to the historical Vallotti temperament.

\[h\]

![Diatonic Impurity as $F(P_{MT}$; $P_{mt}$)[]{data-label="fig. 6"}](Fig_07_new.jpg)

A spreadsheet with solution can be downloaded.

Plenty of combinations of $P_{MT}$ and $P_{mt}$


are possible, but solutions above the C-D line, for ($P_{MT}$; $P_{mt}$) from (0; 0.466) to (0.357; 1), are not WT, because of major thirds exceeding the 81/64 ratio. The almost free choice of $P_{MT}$ and $P_{mt}$ values allows for investigation on which combination might be preferred, taking additional considerations into account, on top of the calculated and desired optimal diatonic C-major impurity. Following musical considerations make sense:

-   Maintain the ***C-major diatonic fifths*** as close as possible to the perfect ratio

-   Achieve a good balance between thirds and fifths impurities

These two points above, require insight into the course of the impurity contributions of thirds and fifths.\
Those ***group*** contributions can be investigated by means of formulas \[equ 16\]. $$RMS_{MT;mt}=\sqrt{\frac{\sum{(\Delta MT_{C,F,G}^2+\Delta mt_{D,E,A,B}^2)}}{13}} \mathrm{;}\ RMS_{Fi}=\sqrt{\frac{\sum{\Delta Fi_{C,D,E,F,G,A}^2}}{13}}
\label{equ 16}$$ Thefavourable ranking.

Comparisons with the Beat-WT model
----------------------------------

Another ranking is possible, ***comparing*** historical temperaments with the obtained Beat-WT model. This comparison makes sense: a low C-major diatonic impurity does not necessarily imply best possible fifths in good balance with thirds, as was indicated during the development of the Beat-WT model (§ 2.2.2). Temperaments can be ***compared***, by calculating the RMS-$\Delta$-Cents of ***mutual impurity differences*** of ***all thirds and fifths***, applying formula \[equ 18\] (with Cent impurities according formula \[equ 9\]).\
$RMS$-$\Delta$-$Cents_{C; C\sharp; D; E\flat; E; F; F\sharp; G; G\sharp; A; B\flat; B} $ $$=\sqrt{\frac{\sum{[(\Delta MT_1 - \Delta MT_2)^2+(\Delta mt_1 - \Delta mt_2)^2+(\Delta Fi_1 - \Delta Fi_2)^2]}}{36}}
\label{equ 18}$$ This formula is useful too, for very precise and accurate ***recognition of temperaments***. ***Recognition*** can be carried out by comparing the unknown temperament with


P_G^2 P_{MT}+25P_D^2 P_{mt}+36k^2 P_B^2 P_{mt}+4k^2 P_E^2 +9P_F^2  )F-12P_F^2  C$\
$ -(30P_D^2 P_{mt}+60kP_B^2 P_{mt} )D-6kP_E^2  E-20kP_G^2 P_{MT} G =20P_F^2 P_{MT} A$\
$\frac{\partial}{\partial G}\mathrm{:}\quad -6P_C^2  C-12P_G^2  D-30P_E^2 P_{mt} E-20kP_G^2 P_{MT} F$\
$+(25P_G^2 P_{MT}+25P_E^2 P_{mt} +4P_C^2 +9P_G^2 )G=0 $

Solution for § 2.2.1.3 Domain above the AB line, fig. \[fig. 5\]
-----------------------------------------------------------------

The model of § 2.2.1, for $P_{MT}=P_{mt}=1$, has major thirds on E, B, F$\sharp$, C$\sharp$ and G$\sharp$ exceeding the 81/64 ratio, and major thirds on F, C and G below the 5/4 ratio. This goes against the formula 2 conditions. Compliance with those conditions was achieved in § 2.2.2, by presetting the AB-line condition (see § 2.2.1.1, setting B=kF, and fig. 5).

An alternate way to achieve compliance with formula 2, might be, in a first step, to preset an 81/64---------- --------
  Pitches              263.32      278.12      294.40      311.64     329.15    352.00
  ***EF-Beat-WT***    F$\sharp$       G       G$\sharp$      A       B$\flat$     B
  Pitches              370,09      393.97      416.35      440.00     468.39    492.47

  :


  \mathrm{\quad hence\quad}   G=\frac{2D^2}{AE}
\label{equ B7}$$ Notes F or B; we have, counting the octaves $$\frac{B}{D}=\frac{2D}{F} \qquad       \mathrm{\ hence} \qquad   F=\frac{2D^2}{B}
\label{equ B8}$$ Notes D and G$\sharp$ being diametrically opposite, we have $$\qquad      G\sharp=D\sqrt{2}
 \label{equ B9}$$\

#### Possible additional substitution (for models with $B/F =2^{10}/3^6$)

Six perfect fifths between B to F, containing an altered note, means also three perfect fifths from G$\sharp$ to F. Setting F and B to the same octave, it can be said. $$B= \frac{2^{10}}{3^6} F \mathrm{\quad and\quad }    F=\frac{3^3}{2^5 }G\sharp=\frac{3^3}{2^5 }\sqrt{2}D \mathrm{\quad hence\quad }  B=\frac{2^{5.5}}{3^3} D
\label{equ B10}$$

#### Possible additional elimination (for WT models with $B/F =2^{10}/3^6$)

See fig. \[fig. A1\]. The line connecting F to B stands perpendicularNguyễn Quang Minh

Nguyễn Quang Minh (born 16 December 1982) is a former Vietnamese badminton player who later played for the United States. He was part of the national team that won the bronze medal at the 2005 Southeast Asian Games. He reached a career high of world number 100 in the men's singles and number 57 in the men's doubles partnered with Trần Thanh Hải. He represented his country at the 2006 Asian Games. Played for the Ho Chi Minh City team, he won the men's doubles title at the 2007 Vietnamese National Championships with Nguyễn Tiến Minh.

Nguyễn left the national team in 2008, and immigrated to the United States. In the US, he won the Dave Freeman Open in 2010 and 2011, also at the Boston Open


worse by the fact that one of the two ruling parties, Matteo Salvini’s Lega, which is hostile towards the EU, made an outstanding electoral performance.

“However, I cannot exclude that, building on the success of the elections, Salvini could be more interested in softening the spat with the EU,” Monti pointed out.

He said he didn’t think Italy was in for a bashing in Brussels. “It’s still a big EU member and it’s not in the Council’s interest to cut ties with Rome, but rather try to keep alive a dialogue that had become a little tarnished in the last year,” he said.

In his view, the Lega’s strategy could shift from harsh words against Brussels to a search for compromise with EU institutions on the application of existing fiscal rules.an effect in terms of less credibility.”

“I think that both quality of the Commissioner and the good chances of passing through the scrutiny of the Parliament will be an asset,” he said, highlighting also the ever-increasing role of gender balance.

Gender balance becomes paramount in race for top EU jobs Initial battle lines were drawn between member states over who will replace Jean-Claude Juncker as European Commission President on Tuesday (28 May) as EU leaders met to discuss “no names, just process”, in preparation for a decisive summit in June.

[Edited by Zoran Radosavljevic and Frédéric Simon]


surrogate indicator of oxphos) and pyruvate carboxylase (PKM, for lactate). While both enzymes were active, supplementation with glucose favoured lactate production. Inhibition of glycolysis using an Akt inhibitor reversed this effect \[[@B68-bioengineering-05-00022]\]. This illustrates that cells can adapt their metabolic activity to their environment. Rat hepatoma cells (JM1) have been probed using \[^13^C\]-labelled glucose while cultivated in either 2D or 3D conditions (encapsulated in alginate beads). These studies showed that in both conditions, 85% of \[^13^C\]-glucose was converted either to lactate or alanine by aerobic glycolysis \[[@B69-bioengineering-05-00022]\].

Jiang et al., compared the metabolic activity of human H460, A549, MCF7, and HT-29 cells grown in 2D and 3D cultures \[1-^13^C\] glutamine or \[5-^13^C\] glutamine tracers clearly illustrated that citrate and lipids predominantly were synthesised via reductive glutaminolysis. In particular, whilephysiological levels in the brain. 100 µm radius spheroids have about 1.6% PO~2~ and larger spheroids less \[[@B76-bioengineering-05-00022]\]. In irrigated spheroids, where media flows past the spheroid, the PO~2~ falls to about 13% measured in the media at the surface of the spheroid \[[@B77-bioengineering-05-00022]\]. Thus, even when irrigated, there is a 'diffusion-depleted zone' in the media surrounding each spheroid (grey zones in [Figure 3](#bioengineering-05-00022-f003){ref-type="fig"}). The PO~2~ reaches a minimal plateau of 3.3% at about 150 µm into a 352 µm radius irrigated EMT6 spheroid, and 1.6% at about 225 µm into a 480 µm radius spheroid. In the latter case, stopping the media flow causes the core PO~2~ to quickly fall to 0. Doubling the flow rate had a marginal effect and was confined to the spheroid surface


While all three processes probably occur, both isotope tracing and enzyme abundance suggests that the latter route is the most active \[[@B57-bioengineering-05-00022],[@B61-bioengineering-05-00022]\].

### 3.4.3. NADH {#sec3dot4dot3-bioengineering-05-00022}

Conversion of α-ketoglutarate to isocitrate requires the cofactor NADPH. The reduction in the mitochondrial MDH2 (−1.35) and the essentially unchanged abundance of its NAD(P) transhydrogenase (NNT 1.13) suggest that the mitochondrial source is of low significance. MDH1 is increased (1.53) but lacks a malate source (the SLC25A11 transporter is reduced −1.28) and the conversion of cytoplasmic pyruvate to lactate would actually consume the NADH that is produced. The richest source of NADPH is the pentose phosphate pathway where G6PD and 6PD are both upregulated (1.90 and 2.37 fold respectively), in agreement with isotope tracing data \[[@B57-bioengineering-05-00022],[@B61-bioengineering-05-00022]\].

### 3.4.4. Citrate {#sec3dot4dot4-bioengineering-05-00022}

Citrate is used for fatty acidunchanged ([Table 1](#bioengineering-05-00022-t001){ref-type="table"}) in concordance with metabolic reprogramming to aerobic glycolysis.

The three rate-limiting glycolytic pathway steps (HK2, PFKL, and PKM) are three of the four most increased enzymes of the pathway (the 4th being aldolase). Interestingly, PFKL is repressed by high ATP/AMP ratios \[[@B101-bioengineering-05-00022]\]. Since spheroids have high ATP amounts \[[@B19-bioengineering-05-00022]\], high PFK levels suggest that AMP levels are also high.

The glutamine-dependent cytosolic carbamoyl-phosphate synthetase 2, is upregulated in spheroids (CAD 3.49). CAD is the rate-limiting enzyme carrying out the first three steps in pyrimidine synthesis. CAD is essential for uridine diphosphate (UDP) synthesis, which in turn, is essential for glycogenesis. This correlates with the appearance of glycogen granules in hepatocyte spheroids and with protein glycosylation and the hexosamine pathway \[[@B102-bioengineering-05-00022]\].

3.7. Signal Pathways Involved in Orchestrating Metabolic Reprogramming


transcription factor MAX. Inhibition of Myc/MAX dimerization prevents specific gene expression, most significantly of p53, cyclin D1 and pro-apoptotic factors \[[@B115-bioengineering-05-00022]\]. Therefore, while Myc regulates many proteins in cancer \[[@B107-bioengineering-05-00022]\], it appears that the slow proliferation of cells in spheroids is a result of low myc activity.

### 3.7.3. p53 {#sec3dot7dot3-bioengineering-05-00022}

The tumour suppressor p53 can transactivate a broad array of target genes that are involved in redox maintenance, DNA repair, cell cycle checkpoints, and can thus affect cellular senescence, proliferation, and apoptosis. Mutations of p53 are found in over 50% of human tumours and disturb the IGF1-AKT branch of the mTOR pathway \[[@B116-bioengineering-05-00022]\].

p53 activity is tightly linked to the oncogene protein DJ-1 (1.83). In a self-regulating loop, DJ-1 is necessary for hypoxic stress-induced p53 activation, while p53 prevents theDenmark. We would also like to acknowledge the support of the COST actions CM1407 (Challenging organic synthesis inspired by nature---from natural products chemistry to drug discovery) and CA16119 (In vitro 3-D total cell guidance and fitness). The funding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, and in the decision to publish the results. We would like to thank Kira Eyd Joensen for excellent technical assistance, Aleksandra Amaladas for help with preparation of glucose/glycogen utilization experiment and Adelina Rogowska-Wrzesinska for critical review of the manuscript.

The following are available online at <http://www.mdpi.com/2306-5354/5/1/22/s1>, Video S1: 17 day old spheroids in clinostat culture.

######

Click here for additional data file.

K.W. and S.J.F. conceived and designed the


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This Meticulously Designed One Bdrm+Den Nearly 1200 Sf Townhome/Loft Will Be Your Own Private Oasis In Downtown Toronto. Lots Of Upgrades: New Floors Throughout, Stairs, New Chandelier/Lights, New Paint. Chefs Kitchen Opens Fluidly Into Dining&Living, Soaring Ceilings, Walls Of Windows-Plenty Of Natural Lights, Den Can Be Converted To 2nd Bedroom, Blinds Can Be Remoted.Front Door From Street/Foyer. Large Private Terrace, Shared Amenities With 500 Sherbourne.to their ambitious tribune. Whatever it was obviously delighted him and he was in high spirits when he ordered his men to break camp, seemingly well able to ignore the worried looks they gave him when he kept going west, moving away from the main army base. Soon they were well past the point that Quintus had laid down as the boundary beyond which his flying columns could not operate with any degree of safety, and, as soon as this was realised, the complaints became vocal, as Aquila and Fabius engaged in a mock-argument as to their precise location, to the point where they were ordered forcibly to remain silent.

'Permission to speak, Tullius?' said Aquila.

The centurion, who had been standing at the top of the rise gazing into


the holder, I would want him to have it.'

They buried their dead with due ceremony and Aquila, as the replacement, spoke the funeral oration for Spurius Labenius, composing a simple speech, but one with the power to wound. He spoke of an ordinary family of farmers, which included the sons of the _primus pilus_ , who had died for the Republic, asking for, and receiving, little reward compared to that bestowed on less worthy men who garnered great wealth and power from the blood of the ordinary Roman. Quintus was angry at the tone of the address, which was clearly aimed at him, but needing to restore senatorial dignity, he decreed that as a signal mark of honour, Labenius's arms and decorations should be taken back to Rome,right round, looking at the platform, with a meaningful stare. 'I've often wondered what it's like to be up here. Somehow I thought the air would smell different, more refined and pleasant, but it doesn't. It still smells of you and horses' piss, in that order.'

They laughed as he held his nose. 'Mind, we've heard some ripe old lies told from up here, lads, haven't we?' Some of the other tribunes looked at each other with alarm as the men cheered loudly in agreement. 'We've been promised everything under the sun from the bastards that have used this spot.'

Now even some of the men looked uneasy. Aquila was pushing it; calling senators of good family bastards, however far away they were, was dangerous stuff. None of them realised


fortress, so there won't be one battle. In fact, I'll be surprised if we don't see a round dozen before we even get near the place. As for casualties, if we get it right, at least one man in five of you won't be coming back. If we get it wrong, none of us will.'

'Then why the fuck are we goin'?' said a voice from the ranks.

'I said I won't lie to you. It's not for glory and it's certainly not an excuse to line some consul's pockets, but going we are. It's the battle we should have fought years ago, and when we leave this camp we're going to be the best men that Rome can put in the field. You're all about to lose some weight,conditions that applied to Pallentia apply here, tenfold. We've got further to go. Instead of building a few bridges, we'll have to construct a dozen. Every inch of the road we build will have to be guarded if supplies are to get through. If we do that, we won't have the troops to attack.'

'I don't intend to attack, at least not right away.'

'Then forgive me, General, but how in the name of Hades Hall do you expect to win?'

Titus indicated the map on the table and gestured for those present to come closer. 'We march straight to our goal. We will bridge only those rivers we can't ford and we'll destroy them behind us. Once we get to Numantia we'll need to live off the land for perhaps


abreast, Marcellus, in the bows, relieved to see that his enemies had done that which he expected; he had no need to abort his progress. Instead he called for more effort.

The Lusitani, thinking the Romans had departed, had broken ranks and they were milling about like a mob, half still on shore, the rest anything from ankle- to knee-deep in the shallows. The horns sounded in panic as their chieftains tried to reform them, which only added to the confusion. The gorgeously clad warrior who had challenged them to battle was in the water, in front of his men, using the boss of his shield to try to get them back into line. Marcellus watched the shore eagerly as it came near, and also the two galleys onHe had also assiduously questioned the skeletons who had survived the siege and noted that when he mentioned Aquila Terentius, they became less willing to speak, as though the name terrified them.

There was a mystery about the man he knew he would have to discover, because now that he had been brought back to Rome, elevated by Titus, and given his radical ideas, there was no doubt he could pose a threat to the Republic.

Cholon was patting her hand. 'You fainted, Claudia. It must have been the journey from Rome. It can be very fatiguing on a hot day. Titus has gone to fetch a physician.'

Behind Cholon's shoulder she could see the tall young man and she could also see, flashing on his chest, the charm in the


place of birth in women and in men. We used log-binomial regression to quantify the association of place of birth with obesity in women and men before and after controlling for selected covariates. We tested interactions terms between place of birth and educational attainment in the fully-adjusted model for women and for men.

Data management procedures were carried out using SPSS 24.0. (IBM, Armonk, NY, USA) whereas the statistical analyses were conducted using SUDAAN 11.0.1 (RTI, Research Triangle Park, NC, USA) to take into account the complex sampling design and yield unbiased standard error estimates. Sample sizes presented in [Table 1](#ijerph-15-01620-t001){ref-type="table"} were a-weighted, but all other estimates (proportions, standard errors, prevalence ratios \[PR\] and their 95% confidence intervals (95% CI) were weighted.

3. Results {#sec3-ijerph-15-01620}
==========

[Table 1](#ijerph-15-01620-t001){ref-type="table"} shows the distribution ofand to have a partner than their native counterparts (all *p*-values \< 0.001). Immigrant men were also less likely to smoke, consume alcohol, be sedentary at work but more likely to have leisure time than native men (*p*-values \< 0.01).

[Table 2](#ijerph-15-01620-t002){ref-type="table"} presents the prevalence estimates for obesity for selected characteristics according to place of birth in men and in women. For women, the prevalence of obesity was higher in immigrants (20%) than in native women (12.5%), with the highest prevalence among those from Africa (30.9%). When compared to native women, older age, low educational attainment, manual social class, married or living couple, and poor perceived health were associated with higher prevalence estimates of obesity among immigrants (all *p*-values \< 0.001). In addition, lower prevalence of obesity was associated


natives is also consistent with previous studies in Europe regardless of the country of birth \[[@B14-ijerph-15-01620],[@B15-ijerph-15-01620],[@B16-ijerph-15-01620],[@B26-ijerph-15-01620],[@B32-ijerph-15-01620],[@B34-ijerph-15-01620]\]. In addition, similarly to studies conducted in the Netherlands \[[@B16-ijerph-15-01620]\] and Sweden \[[@B14-ijerph-15-01620]\] with immigrants from Morocco, sub-Saharan Africa Central and South America, obesity inequalities between native and immigrant women, persist after adjusting for sociodemographic characteristics and health behaviors. Hence, place of birth in women may be considered a social determinant of obesity inequality. For women, factors associated with double discrimination, gender and immigration status, can explain their greater prevalence of obesity.

Despite the extant evidence on the protective effect of higher educational attainment on health status and specifically in obesity \[[@B18-ijerph-15-01620],[@B19-ijerph-15-01620],[@B21-ijerph-15-01620],[@B22-ijerph-15-01620]\], we found a protective effect at lower educational levels in immigrant men relative to their native peers. This finding may befor the immigrant population. The lack of this information may have masked greater obesity inequalities between the immigrant and the native populations. However, we repeated the analyses using region of birth (Europe, Latin America, Africa and Asia). Although not statistically significant, the results were consistent to the ones reported here for men (lower PR for immigrant relative to native) and women (higher PR for immigrant than native) with the exception of Asian women who exhibited lower prevalence of obesity than their native counterparts. Third, BMI was calculated using self-reported weight and height by the respondents. Evidence suggests that women may underestimate the body weight while men may overestimate their height. This misreporting may have biased the actual prevalence of obesity \[[@B43-ijerph-15-01620]\]. Finally, the proportion of missing values for


it the researchers discovered hardcoded AWS keys and keys for Azure, Microsoft’s cloud computing platform, along with “other internal proprietary information, such as usernames and passwords.

Finally, the researchers discovered a shared AWS key granting access to customer financial data tied to a financial services company, in addition to “trade secrets that included financial models and possibly direct consumer data.”

“Our intention with releasing this information was not to attack customers or security vendors, and we don’t pretend that we’ve performed an exhaustive analysis of the breadth of the leaks,” Broome writes. “We only know that every time we looked, we found this same serious breach of confidentiality.”

Broome concluded that DirectDefense was unsure if the problem was unique to Carbon Black, “only that Carbon Black’s prevalence in the marketspace andfilename saved in the specified folder. Something like this:
{
   "id":"6454364d8facd7a88e627e9329ffc2b7a5c879dc838.jpeg",
   "uri": "the-same-uri-we-uploaded",
   "size": 1156
}

Here, the "id" is the filename.
Then you can attach this file name to the user object as:
{
   email:  this.state.Username,
   Nom: this.state.Name,
   Image: "6454364d8facd7a88e627e9329ffc2b7a5c879dc838.jpeg",
}

and save it using the users service or whatever you are already using to save the user.
Also, if you want to do it in a single request, then submit the file and user data to users service and in a before hook call the uploads service, save the file and attach this data in the user object, so that the users service can save it.
Also, remember to save your images in public/images folder so that they


median follow-up of 2.8 (1.2--4.9) years, 72 patients died due to CVD (29 (40.3%)), infection (23 (31.9%)), malignancy (9 (12.5%)), and other causes (11 (15.3%)). The relationship between the GNRI and the ECF/ICF ratio with all-cause and cardiovascular-specific mortality is summarized in [Table 3](#nutrients-11-02659-t003){ref-type="table"}.

In the univariate Cox proportional hazards analysis, the GNRI and the ECF/ICF ratio were significant predictors for both all-cause and cardiovascular mortality. First, we divided patients by the median GNRI into low and high groups: the 10-year all-cause survival rates were 18.7% and 67.0%, respectively; the 10-year cardiovascular survival rates were 48.7% and 83.3%, respectively (*p* \< 0.0001, all). Second, we divided patients by the median ECF/ICF ratio into low and high groups: the 10-year all-cause survival rates were 0% and 84.6%, respectively; the 10-yeara = "Hola chico raro" // declaramos la cadena
mi_cadena_inicia_con_h = cadena.inicia_con(a, "H")
si mi_cadena_inicia_con_h
  imprimir("La cadena 'a' inicia con la letra H")
sino
  imprimir("La cadena 'a' no inicia con la letra H")
fin


between the levels of projections and depressions is about equal to the wavelength of light, so that light is diffracted. By contrast, in Fresnel lenses, the difference between the levels of projections and depressions is several times or more as great as the wavelength of light, so that light is deflected exclusively by refraction.
Diffractive optical devices and Fresnel lenses have the great advantage of being thin optical devices.
According to the Japanese Patent Application Laid-Open No. H10-197827 mentioned previously, a polarization separation device is built as a diffraction grating formed out of an isotropic transparent material, and an optically anisotropic layer formed out of a birefringent material, and the like. However, even when a diffraction grating is formed out of an isotropic transparent material, unless due consideration is givenThe Kansas Court of Appeals recently ruled that dismissal of a case based on the statute of limitations does not constitute a favorable termination and will not support a claim of malicious prosecution.   Miskew v. Hess, 910 P.2d 223, 233 (Kan.App.1996).  In framing its own decision, the Miskew court adopted the reasoning of other courts that had rejected favorable termination claims based upon statute of limitations dismissals:

17
[B]ecause a favorable termination should indicate the innocence or nonculpability of the accused, the favorable termination must reflect on the merits of the initial action.  The court observed that the dismissal of a case based on a statute of limitations defense is not on the merits.  '[T]he purpose served by dismissal on limitations grounds is in no


           params["_err"] = open(os.devnull, "wb")

        with params["_err"]:
            stream = cmd(**params)

        # Wait 0.5 seconds to see if program exited prematurely
        time.sleep(0.5)

        process_alive = stream.process.returncode is None

        if not process_alive:
            if self.errorlog:
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         [Acute and chronic alcohol abuse--effect on inpatient treatment of trauma surgery patients].
The effect of alcoholism on the length of stay and costs of hospital treatment is not well documented. The posttraumatic course of treatment of 75 alcohol intoxicated patients was prospectively followed. A shortened MAST-test served to identify chronic alcoholised patients. The obtained data were compared with a control group according to the matched-pair method. The course of treatment of 44 drunken patients without signs of chronic alcoholism was not different from the control group. However 31 chronic alcohol intoxicated patients showed a clearly different course from the control group. The hospital stay was nearly doubled (13.5 days) compared to the control group (7.5 days). There were explicitly more consultations of specialists (26 vs. 9) necessary and the


team, Stevens was the last he’d imagine becoming a coach. He was too smart, too bound for success elsewhere.

“He’s going to make a lot more money in whatever he does than coaches could ever make,” Sollman believed.

Friends, family, coaches, former teammates, and colleagues say he is one of the rare few who would have excelled at anything because of his intellect and drive. But growing up in the basketball-steeped culture of Indiana and coaching in Butler’s Hinkle Fieldhouse, a national historic landmark that was once the largest gym in the US and was where part of “Hoosiers” was filmed, all but ruined him for anything else.

He is all-ball, a Hoosier in search of anything with a scoreboard, who no longer plays as an outlet for his ultra-competitiveness but[Synergic effect of alprostadil injection and ginaton in treating sudden deafness].
To explore synergic effect of Alprostadil injection and ginaton in treating sudden deafness. ninety one patients with sudden deafness were divided into group A, group B and group C at random; 33 ears of group A were treated with 70 mg ginaton by vein, 30 ears of group B were treated with 10 microg Alprostadil injection by vein, 31 ears of group C were treated with 10 microg Alprostadil injection and ginaton by vein,once a day, the time of treatment is 14 days. the effective rate of group A is 60.61%, the effective rate of group B is 60.00%, the effective rate of group C is 87.09% the treating effect was significantly different in the group A and


with one clean rag and wipe off with another. Superficial scratches can catch the light and make damage seem large. Shadows can appear as dents. If the paint and metal aren’t actually damaged simply buffing out the scratches will improve your appearance dramatically.

Another trick we’ve heard of, but not had a chance to try yet is taking a common house plunger to medium-sized dents. We’ve used some of the commercially available dent removal options with mixed results. Honestly, anything that starts with the words, “drill a whole,” is something you want to live with or pay a pro.more integrative and interpretable. Sparse Logistic Regression [@shevade2003simple] is one such model. As is known to all that logistic regression is a popular model for clinical risk prediction [@miravitlles2000factors] [@sun2012combining][@wu2010prediction]. However, the pool of potential risk factors is usually very large and noisy, which would affect the efficiency and performance of predictive modeling. The main difference between sparse and conventional logistic regression is it adds an one norm regularizer on the model coefficients to encourage the model sparsity, so that only those [*important*]{} risk factors will contribute to the final predictions. In recent years people have also been doing research on constructing different regularization terms to enforce different sparsity structures on the model coefficients, such as the $\ell_p$ norm [@liu2007sparse], group sparsity [@meier2008group] and elastic net regularization [@ryali2010sparse].

One


representation of patient Electronic Health Records (EHRs) to capture the interactions between different [*modes*]{} in patient EHRs. For example, medication order information for every patient could be captured by a 2nd order tensor with 2 modes, where each mode is an aspect of a tensor: a) medication and b) diagnosis. With such a representation we can take into consideration the correlation between diagnosis and drugs when predicting the patient risk. If there are more inter-correlated modes in the data then we will need to represent the patient in higher order tensors. In these cases, if we still want to apply logistic regression one straightforward way is to stretch those matrices and tensors into vectors as people did in image processing, but this will lose the correlation information amongnicotine or e-cigarette use; andContinuous smoking abstinence forat least six months with no medicinal nicotine or e-cigarette use for 3 months or more.

Secondary outcomes {#Sec27}
------------------

The secondary outcomes are:Seven-day point prevalence abstinence measures of the above primary outcomes;The proportion of each condition concurrently using medicinal nicotine and cigarettes, the quantity of each consumed, their interest in quitting smoking, and interest in eventually quitting all medicinal nicotine;The proportion of condition C concurrently using e-cigarettes and cigarettes, the quantity of each consumed, their interest in quitting smoking, and interest in eventually quitting all use;The quantity of cigarettes consumed by current smokers as a function of medicinal nicotine or e-cigarette use in each condition, and their interest in quitting smoking;The proportion of each condition that order a product, what product is ordered, the amount


1. Field of the Invention
The present invention relates to a method of fixing a polygon mirror used for scanning laser beam in a laser beam printer or a digital copier to a side of a rotating member of a motor and a polygon scanner motor using the fixing method.
2. Description of the Related Art
In an optical system such as a laser beam printer or a digital copier, there is used a polygon scanner motor as means for scanning laser beam. A polygon scanner motor of this kind is constituted by fixing a polygon mirror which is formed as a polygonal member in a shape of a thin plate comprising a material of, for example, aluminum and a side face of which is formed by a light reflecting facea drawback in scanning light to the reflecting face of the polygon mirror.
Further, when a flange member of a rotating member is fitted to an attaching hole of a polygon mirror, an outer peripheral edge of the flange member is plastically deformed outwardly to be brought into press contact with an inner peripheral edge of the attaching hole of the polygon mirror to thereby achieve bonding of the rotating member and the polygon mirror as is disclosed in, for example, Japanese Patent Laid-Open No. 230268/1997, there poses a problem that there is operated force in a direction of bringing the polygon mirror into press contact with the rotor by calking, thereby, attitude of the polygon mirror is deviated from required attitude relative to the rotor, rotational balance is


expansion coefficients substantially equal to each other to thereby enable to prevent a state of bonding the polygon mirror and the rotor from being changed by a change in temperature. The polygon mirror and the rotor can be constituted by the same metal material.
According to another aspect of the invention, there is provided a polygon scanner motor which is a polygon scanner motor constituted by fitting and fixing an attaching hole of a polygon mirror formed with reflecting faces for scanning light at side faces thereof to a projected portion provided at a rotor of a motor wherein the projected portion includes a fitting face end edge opposed to a vicinity of a center in an axial direction of an inner peripheral face of the attaching hole offactor in SSc susceptibility and discovered two non-HLA, African ancestry-specific loci, IFT43/TGFB3 and FSD2/HOMER2. rs35915063 was the top scoring variant in the HLA-DQB1 gene (P=2.2 x 10e-17, OR=1.96). Stepwise conditional regression analysis using an additive model revealed the DQA1 variant rs9271620 and the DPB1 variant rs2071354 as independent risk variants. Upon performing eQTL analysis in whole blood from the GTEx RNA sequencing data, the African-American SSc-associated alleles of these 3 risk variants were associated with increased expression of HLA-DQB2/DQA2 and decreased expression of HLA-DQB1 and HLA-DQA1 genes. rs59063398 showed the strongest non-MHC association (P=2.0 x 10e-8, OR=0.47). This variant is part of an evolutionarily conserved haploblock in the IFT43 gene region that is African ancestry-specific. On performing eQTL analysis of the GTEx RNA sequencing data of sun-exposed skin


of the lower leg, we observed decreased expression of TGFB3 associated with the minor variant in the IFT43/TGFB3 region (P=0.02). We used MHC region genotypes from the MEGA array to impute classical HLA types and analyzed their associations with scleroderma in the GRASP cohort. We extracted the genotypes of 25,256 markers from 20 Mb encompassing the greater MHC region to impute classical HLA types using the HLA*IMP:03 web server. The most significantly SSc-associated HLA type was a predominantly African allele, HLA-DRB1*08:04, OR=2.95. Regression analysis conditioning on the disease-associated alleles identified another African DRB1 allele, *11:02, as well as HLA-DPB1*13:01 and HLA-DRB4*01:01 as independent contributors to disease risk, but no association was found for MHC class I alleles. 34.6 percent of GRASP cases carry either DRB1*08:04 or *11:02 comparedsets.

If you find a match, stop comparing pairs and start over with the first item in the first group.  (Using deferred execution here helps you, so that you don't bother pairing up the groups as soon as you find a match.)
If you go through the entire set without finding a match then you are done, there are no more combinations to be made.

So, walking through your example.  First it would pair up the first and second groups.  The first two category sets are the same, the third is different, so they can be merged.  You now have a list that is:

[Cat], [Blue], [Long, Short]
[Dog], [Blue], [Long]
[Dog], [Blue], [Short]
[Dog], [Green], [Long]
[Rat], [Red], [Short]
[Rat], [Blue], [Short]

Next we compare the (new) first and second groups.  Both


at preinjection and 2 weeks, 6 weeks, 6 months, and 1 year postinjection. The groups were compared with regard to repeated injection or surgery within 1 year after the initial procedure. The fluoroscopic time and the procedure-related complications including severe pain (visual analogue scale score>7) during injection, dural puncture (subdural contrast spread), headache, neurological symptoms, and infection were also compared. There were no significant differences in leg pain, back pain, or Oswestry Disability Index improvement at each visit between the ventral ESI group and the conventional ESI group (all P>0.05). The numbers of repeat injections and surgical procedures were not significantly different between 2 groups (P=0.262 and 0.385, respectively). There were no significant differences in severe pain at injection (P=0.326), dural puncture (P=0.428), headache (P=0.393), neurological symptom (P=0.419),MagicalSakura I spent two weeks working on this picture of Vivian James for Gamergate. I was watching a stream ofand she said that she had a special technique where she'd use masking instead of clipping layers to color in subsections of the picture that had to be contained in a smaller area. She complained that people always asked her what her technique was and that whenever she told them, they'd always get stubborn and say that they liked their way better. I decided to give her technique a try, and I like it.

To blend in everything, I used the watercolor tool at default settings though with the falloff set to hard so that things weren't blurry and muddy.

And with Gamergate, I've been following GG and learned a lot


Hamiltonian}
{V_{\mathrm{MBO}}}(x,\{Q_i\})={V_{\mathrm{S}}}(x)+\sum_{i}\frac{1}{2}\omega_{i}^{2}\left (Q_{i} - \frac{g_i}{\omega_i^2} x\right )^2
\enspace .$$ This form of the CL model is often termed multi-mode Brownian oscillator (MBO) model [@Mukamel1995]. Here we will adopt this terminology and refer to [Eq. (\[eq:CL Hamiltonian renormalized\])]{} and to [Eq. (\[eq:MBO Hamiltonian\])]{} as to the CL and the MBO model, respectively. Note that there are no differences between the models, apart from the presence/absence of the aforementioned renormalization term.

Given the similarity of the models, a GLE can be derived from either of them both in the classical [@Zwanzig1973; @Cortes1985a; @ZwanzigBook2001] and quantum [@Ford-JSP-1987; @Ford-PRA-1988] domains; the respective subscripts (CL or MBO) will be omitted from now on unless there would be a need for explicit distinction. Limiting ourselves to the classical description, the derivation can be straightforwardly performed without any further approximations by integrating the@Gottwald-JCP-2015]. Our previous analysis yielded that the aqueous systems considered in [@Gottwald-JPCL-2015] exhibited almost linear coupling on the system side (the deviations were smaller that 2%), whereas for the ionic liquid considered therein it was completely non-linear (the deviations were up to $\approx 40\%$). The Gaussianity of the noise revealed the opposite trend, that is the noise was not centered at zero and fairly asymmetric for aqueous systems, whereas it was almost Gaussian and zero-centered for the ionic liquid considered. Since the GLE spectrum for the ionic liquid was closer to the MD results compared to those of the aqueous systems, which were miserably wrong in shape and peak position, we concluded that Gaussianity might be more important than the linearity of the coupling on the system side [@Gottwald-JPCL-2015].


of about 25% in the liquid regime and about 10% in the solid regime. Performing a quadratic fit shows an improvement in both cases, which underlines that the linearity assumption of the coupling does not hold for the investigated system. In general, having a higher non-linearity in the liquid regime is expected as the motions are of larger amplitude than in the solid regime. One might wonder, whether a quadratic dependence of the system-bath coupling on the bond length indicates that the MBO model is to be preferred to the CL model, as, in the MBO model, the quadratic counter-term is viewed as a part of the system-bath coupling, see [Eq. (\[eq:MBO Hamiltonian\])]{}. Then, this quadratic term should coincide with the renormalization term, [Eq. (\[eq:renormalized Potential\])]{}. However, the renormalization termcould not be responsible for this quadratic behaviour as it turned out to be orders of magnitude different. Furthermore, the renormalization term does not depend on the particular bath configuration, whereas the quadratic fit coefficient exhibits strong dependence on bath coordinates. The assumption of a Gaussian distributed noise (panels b and e) is sufficiently verified for the solid regime. In the liquid regime one observes a slightly asymmetric profile that still fits well a Gaussian shape. In both cases the mean of the noise is not centered at zero but at negative values. This can again be attributed to the high pressure which, on average, produces environmental forces that shrink the I$-$I bond. This, however, results only in small shifts in the spectra, see [Fig. \[fig:results\]]{}, implying that the


  >'ice/cice/ar9v1_20090520.kmt'       </kmt_file>
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<kmt_file hgrid="us20"      >'ice/cice/domain.ocn.us20.20110426.nc'</kmt_file>

<gridcpl_file               >'unknown_gridcpl_file'                </gridcpl_file>
<gridcpl_file hgrid="ar9v2" >'ice/cice/domain.ocn.ar9v2.090614.nc' </gridcpl_file>
<gridcpl_file hgrid="ar9v4" >'ice/cice/domain.ocn.ar9v4.100920.nc' </gridcpl_file>

<kcatbound> 0 </kcatbound>

<!--------------------------->
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<ndte> 120 </ndte>
<maskhalo_dyn>.true.</maskhalo_dyn>
<maskhalo_remap>.true.</maskhalo_remap>
<maskhalo_bound>.true.</maskhalo_bound>
<maskhalo_stress>.true.</maskhalo_stress>
<splitcomm_dyn>.false.</splitcomm_dyn>

<!--- ice albedos --->

<albicev  hgrid="gx3v5" >0.68</albicev>
<albicev                >0.75</albicev>
<albicei  hgrid="gx3v5" >0.30</albicei>
<albicei           Right now, that’s what we do with Social Security. It is a popular program. It is a universal program,” he continued.

Buttigieg has proposed limiting free public college tuition to American households with incomes of $100,000 a year or less. He has also called for $50 billion in new investments in historically black colleges and universities and minority-serving institutions.


my blood sugar has been alot lower. I am also on Glyburide which helps keep it lowered but the club soda has lowered even more. Which is awesome.

Amanda

Does anyone have any suggestions/cautions/information about the Sodastream? I just got one for my birthday and I really love it, but I’m diabetic. I’m not a big soda drinker so I stick mostly to the Kool-aid and diet flavors like Pink Grapefruit. I’ve also started just adding the liquid drops of flavor to the plain carbonated water just like you can regular water but I starting wondering if the carbonation might be bad for me.

MARK LULLEY

Amanda, I have a Soda Stream for a year now. I live in the Caribbean. I use it every day and drink a tremendous amount ofdown to a safe level.

jezz2k .

In regards to carbonic acid, is it safe to brush my teeth 10 minutes after drinking sparkling water? I want to switch from Diet Pepsi because I believe drinking that before brushing my teeth is what caused them to start eroding 🙁

acampbell

Hi jezz2k,
It should be fine to brush your teeth after drinking sparkling water. The amount of carbonic acid in the water is very low.

MaryKay Simoni

I don’t think carbonated water is bad for your teeth or contributes to diabetes etc….What I’m concerned about, that no one has mentioned is the fact that you’re introducing carbon dioxide into your system, which is a waste product. After all, many like to add oxygenated expensive drinks. Am wondering if anyone has researched this aspect. Thanks.

acampbell

Thanks for


            $('#dectinationDivId').html(data);
                $('#buttonId').hide();
            },
            error: function(jqXHR) {
                alert(jqXHR.responseText);
            }
        });
    });
</script>

For multiple buttons there is a better, more generic, approach which makes it easier to maintain code (add and remove buttons, in this case).
HTML/JS:
<script src="http://code.jquery.com/jquery-2.1.3.min.js" type="text/javascript"></script>
<script type="text/javascript">
    $(document).ready(function() {
  lead the climate change and health assessment for the two health units.

What does this mean?

We’ll be looking at specific risks to the Region of Waterloo, City of Guelph, County of Wellington and County of Dufferin. Localized climate projections predict increased annual temperatures, more extreme heat days, and more intense precipitation (rain, snow) and wind resulting in property damage and flooding.

We already are seeing more frequent and violent thunderstorms, and other types of severe weather affecting water supplies and agricultural production. Food or water shortages and illnesses related to drinking water contamination could be coming to a neighbourhood near you. Those who live in inadequate housing or unprepared neighbourhoods are particularly at risk and this study will look how to reach out and help the most vulnerable among us.

The


to the end of November 2012 when she consulted a local hospital and *Streptococcus viridans*was detected by blood culture. Transthoracic echocardiography (TTE) revealed the presence of vegetations on the aortic and mitral valves with regurgitation. On the basis of the Duke criteria, she was diagnosed with definite infective endocarditis (IE), and intravenous antibiotic treatment (penicillin G 18 × 10^6^ units/day + gentamicin 80 mg/day) was started. She was admitted to our hospital on December 6, 2012.

On presentation, her clinical characteristics were height 155 cm, weight 50.9 kg, blood pressure 141/76 mmHg, heart rate 93 beats per minute regular, body temperature 36.4°C, SpO~2~ (room air) 96%, and heart sound systolic murmur (Levine IV). Blood test data were as follows: WBC 6.17 × 10^3^/*μ*L, C-reactive protein 1.7 mg/dL, aspartyl aminotransferase 29 IU/L, alanine aminotransferase 17 IU/L, lactate dehydrogenaseoptical axis by using an L-shaped guide shaft. The guide shaft guides the correction lens in a direction at an angle of 45 degrees with respect to the direction of driving by the actuator.
In each of the optical image stabilizers disclosed in Japanese Patent Laid-Open No. 11(1999)-258651 and No. 10(1998)-197911, the guide mechanism for preventing the rotation of the correction lens about the optical axis causes the correction lens to move in parallel through sliding. This presents a problem in which sliding friction produced in the guide mechanism reduces driving responsivity especially when the correction lens is driven slightly.
To address this, Japanese Patent Laid-Open No. 2004-101721 has disclosed an optical image stabilizer that prevents the rotation of the correction lens about the optical axis by using a ball


used to study the behavior of the sheet structure. Auto- and cross-correlation functions are calculated from the time histories with relaxation times of tens to hundreds of picoseconds. Sheet-coil rate constants of tens of ns-1 were found for the fixed strand cases.surrendering control of America’s destiny to a rival superpower — and all without a shot being fired.

Consider the scale of the problem.

With President Obama’s 2010 budget, 42 cents of every dollar the federal government spends will have to be borrowed. In the last decade, foreign investors have wound up lending us roughly half of all federal debt — with just two countries, China and Japan, providing nearly half of that sum, or 44 percent, through the purchase of US Treasury securities.

China now tops Japan as our biggest lender by some $30 billion a year, at $789 billion. (By comparison, our No. 3 lender, Great Britain, comes in at a measly $277 billion).

But that’s not all. As its booming economy becomes more global, China is also the world’s largest


Secretary may require equitable contribution from interested persons or agencies desiring such alteration as a condition precedent to ordering the alteration. 229 Id. 280 Act of August 18,1894, § 5, 28 Stat. 338, 362, as amended, 33 U. S. O. 499.","id":1138497,"created_tdt":"2005-09-21T00:00:00Z","parent_i":1139162,"_version_":1613593364781858816}]},"highlighting":{"1138497":{"ocr_t":[]}}}HAVE_STRNDUPA
+static inline char *strndupa(const char *old, size_t n)
+{
+	size_t len = strnlen(old, n);
+	char *tmp = alloca(len + 1);
+	tmp[len] = 0;
+	return memcpy(tmp, old, len);
+}
+#endif
+
 /* Returns 0 on success and 1 on error */
 static int extract_timestamp(const char *b, au_event_t *e)
 {
diff --git a/auparse/interpret.c b/auparse/interpret.c
index 51c4a5e..67b7b77 100644
--- a/auparse/interpret.c
+++ b/auparse/interpret.c
@@ -853,6 +853,13 @@ err_out:
 		return print_escaped(id->val);
 }

+// rawmemchr is faster. Let's use it if we have it.
+#ifdef HAVE_RAWMEMCHR
+#define STRCHR rawmemchr
+#else
+#define STRCHR strchr
+#endif
+
 static const char *print_proctitle(const char *val)
 {
 	char *out = (char *)print_escaped(val);
@@ -863,7 +870,7 @@ static const char *print_proctitle(const char *val)
 		// Proctitle has arguments separated by NUL bytes
 		// We need to write over the NUL bytes with a space
 		// so that we can see the arguments
-		while ((ptr  = rawmemchr(ptr, '\0'))) {
+		while ((ptr  =


receive_bytes(rest);
    }

    return received;
}

/**
 * @brief Send the message `msg` as one frame.
 * @returns How many bytes were sent; should be `msg.size()`.
 * @throws socket_exception
 */
ssize_t dgram_over_stream::sndmsg(const std::vector<uint8_t>& msg) {
    return sndmsg(static_cast<const void*>(msg.data()), msg.size());
}

/**
 * @brief Receive up to `dst.size()` bytes and store them in `dst`.
 * @returns Number of bytes actually received.
 * @throws socket_exception
 *
 * Resize `dst` before calling in order to adjust the number of bytes you will
 * receive.
 */
ssize_t dgram_over_stream::rcvmsg(std::vector<uint8_t>* dst) {
    uint32_t expected = receive_header();

    if (expected <= dst->size()) dst->resize(expected);

    size_t to_receive = dst->size();
    size_t received = 0;
    std::vector<uint8_t>::iterator dst_iter = dst->begin();

    while    received += result;
    }

    // Consume remaining frame that doesn't fit into dst.
    ssize_t rest = expected - to_receive;
    while (rest > 0) {
        rest -= receive_bytes(rest);
    }

    return received;
}

/**
 * @brief Send the message in buf with length len as one frame.
 * @returns The total number of bytes sent.
 * @throws A socket_exception.
 */
ssize_t dgram_over_stream::sndmsg(const void* buf, size_t len) {
    encode_uint32(uint32_t(len), prefix_buffer);
    ssize_t result = inner->snd(prefix_buffer, FRAMING_PREFIX_LENGTH, 0);

    if (result < 0) return result;

    result = inner->snd(buf, len, 0);

    if (result <


0) return result;

    return result;
}

/**
 * @brief Receive a message and store the first `len` bytes into `buf`.
 * @returns The number of bytes received.
 * @throws A socket_exception.
 *
 * Bytes in the message beyond `len` are discarded.
 */
ssize_t dgram_over_stream::rcvmsg(void* dst, size_t len) {
    uint32_t expected = receive_header();

    size_t to_receive = len < expected ? len : expected;
    size_t received = 0;

    while (received < to_receive) {
        ssize_t result = receive_bytes(to_receive - received);

        if (result < 0)
            throw socket_exception(
        We're now in the process of designing the final product and can't wait to get it in to your hands this summer. And that's where you come in. We're raising funds here on Kickstarter primarily to help cover printing and production costs. About two-thirds of the money go toward producing a big, beautiful, offset-print magazine. We want to really showcase the people and the work in its best possible light. And, because we're working with you to fund this, Issue #1 will be completely ad free! Any money raised on top of this will go towards shipping and contributor costs, as well as business setup costs to help get this thing off the ground.

Your Rewards

Every backer will receive a free copy of Issue #0, our 12-page promotional newspaper


     (i < flightPath.getPath().getLength() && dist < metres); i++) {
      olddist = dist;
      dist += google.maps.geometry.spherical.computeDistanceBetween(
        flightPath.getPath().getAt(i),
        flightPath.getPath().getAt(i - 1)
      );
    }
    if (dist < metres) {
      return null;
    }
    var p1 = flightPath.getPath().getAt(i - 2);
    var p2 = flightPath.getPath().getAt(i - 1);
    var m = (metres - olddist) / (dist - olddist);
    return new google.maps.LatLng(p1.lat() + (p2.lat() - p1.lat()) * m, p1.lng() + (p2.lng() - p1.lng()) * m);
 reports have shown that SR can both promote bone formation and inhibit bone resorption \[[@b14-medscimonit-24-6525]--[@b16-medscimonit-24-6525]\]. Additionally, it can promote fracture healing by increasing osteogenesis and bone formation in the fracture site, thereby improving the microstructure of trabecular bone and enhancing the biomechanical properties of the callus \[[@b14-medscimonit-24-6525],[@b17-medscimonit-24-6525]\]. Moreover, SR increased the expression of the osteoblast marker osteocalcin (OCN) \[[@b14-medscimonit-24-6525]\]. We therefore hypothesized that SR would promote fracture healing in rats with estrogen deficiency and T2DM when pre-treated with insulin. In the present study, we evaluated the effect of SR combined with insulin on the healing process of a fracture model in OVX rats with T2DM induced by the consumption of a high-fat diet (HFD) and the injection of a single low dose of streptozotocin (STZ).

Material and Methods
====================

Animals and


estimate of the percentage of immunoreactive cells (A, quantity score) with an estimate of the staining intensity (B, staining intensity score), as follows: A, no positive cells=0, 1--10% positive cells=1, 11--50%=2, 51--80%=3, and 81--100%=4; B: negative=0, weakly positive=1, moderately positive=2, and strongly positive=3 \[[@b29-medscimonit-24-6525]\].

Statistical analysis
--------------------

All data are given as means ± standard deviation and were analyzed using SPSS version 19.0. A one-way analysis of variation was performed to analyze all data. Post hoc analysis was performed using an LSD test or Dunnett's T3 test, as appropriate. A value of P\<0.05 was considered to indicate a significant difference.

Results
=======

Establishment of animal model
-----------------------------

The survival rate of rats treated with the STZ injection was 91.9%, and the success rate for T2DM model establishment was 86.5%. The remaining animals tolerated the fracture procedurehad to demonstrate that she was up to task and able to not only replicate the work of her predecessor, but to actually prove herself as her own unique performer. Thankfully for her, if reviews and comments are anything to go by, she has proven her worth more than enough.

If I want to look sexy I’m going to do it, and you’re still going to listen to my music because it’s fucking good music!

Metal Blast: When you were first offered the position as Angela’s replacement, how much of a challenge did you feel you were going to face filling her shoes? Alissa: Angela is very iconic and broke down a lot of barriers not just for women in music, but in music in general. It’s not a simple


in some new elements later, but I’m really happy to play the old songs live in Angela’s style, then play the new songs in a little bit more of my style.

Photo: Patrick Ullaeus

MB: In The Agonist, for instance, you had a lot of clean singing mixed with the growling vocals, while in Arch Enemy, of course, they prioritized the growling. Do you think that it’s possible to have the sort of clean/growling style in Arch Enemy, or do you think it’s best to continue with just the growling in the band?Alissa: Although right now I feel like Arch Enemy sound good with mostly just growls, I still do a very musical growl, since I include melody in it. In any case, I don’t feel like Arch Enemy reallynew band that I just mentioned, for example, it’s all girls because they’re my friends, and they’re also the best musicians that I know so, of course, I’m going to have a band with them. I think it’s a little silly to be like “hey look, there’s a girl in this band!” So what?! Show me the music, and then I’ll tell you if I like the band.

Photo: Patrick Ullaeus

MB: As a female musician in the industry, do you feel like sometimes labels fall into exploiting the fact that one of the performers is a woman in order to get more views on the music videos and so on?Alissa: I think it’s only exploitation if they’re doing something that the band doesn’t want to do. If any female,


corresponding peak shift in the ultraviolet-visible spectrophotometry (UV-vis) or surface plasmon absorption spectrum. Color changes can be easily observed by the naked eyes in the AuNP colloid solution with nanomolar concentration. Therefore, these nanoparticles exhibit potential for colorimetric sensing. Colorimetric assays based on AuNPs for the detection of cancer has been reported in a previous study, it displayed many great advantages.[@b30-ijn-11-5335] Chen et al utilized AuNP probes for the DNA methylated detection of *E-cadherin, p15*, and *p16* genes in three human colon cancer cell lines, which showed that this method is simple, rapid, and has a high sensitivity to simultaneously detect methylation.[@b30-ijn-11-5335] However, there were no studies utilizing nanoparticles for the detection of cervical cancer.

In this study, we present a novel method for direct colorimetric detection of *PAX1*primers were used.

Control experiments were conducted using the extracted DNA of IVD and NL, which represent unmethylated *PAX1* gene (*PAX1^m^*^−^) and methylated *PAX1* gene (*PAX1^m^*^+^), respectively. Instantaneous color change from red to purple-gray was observed from 0 to 6 minutes in the AuNP colloid solution containing the *PAX1^m^*^−^ specimen. The color change could be due to salt addition. UV--vis spectroscopy showed a narrow peak located at 520 nm at the beginning, and the peak shifted from 520 to 660 nm within 6 minutes. The band became broad, and the optical density value of absorbance decreased as the time increased. This finding indicated the aggregation of AuNPs after salt addition ([Figure 2A](#f2-ijn-11-5335){ref-type="fig"}). By contrast, the color of the AuNP colloid solution with the *PAX1^m^*^+^ gene remained red after salt


SCC were 16.67%, 15.38%, 57.14%, 100%, and 100%, respectively. The methylated percentages detected by qMSP in normal, CIN1, CIN2, CIN3, and SCC were 33.33%, 46.15%, 85.71%, 100%, and 100%, respectively. The results of the two methods showed that the percentage of methylation of the *PAX1* gene is higher in HSIL or SCC than that in minor cervical lesions, such as ASCUS, ASCUS-H, and LSIL.

The distribution of methylation level Δ*Cp* in different clinical and pathological characteristics is shown in [Table 3](#t3-ijn-11-5335){ref-type="table"}. The methylation status of the *PAX1* gene was not associated with patients' age, cytology, and HPV. The results of both methods showed that the methylated frequency of the *PAX1* gene was significantly associated with pathological features.

Discussion
==========

DNA methylation could be a suitable biomarker for the detection of cervical cancer.with enzyme-linkage reactions showed that with the increase of the inhibitor concentration, the velocity of methylation decreased and the ratio of absorbance A~620~/A~520~ increased slowly.

Apart from the direct colorimetric methods of AuNPs and UV--vis spectroscopy, many studies have demonstrated that AuNPs exhibit various optical properties for the detection of DNA in cancer therapy.[@b39-ijn-11-5335]--[@b41-ijn-11-5335] AuNPs hold great promises in the detection of cancer because of their good biocompatibility, easy synthesis and functionalization, chemo-physical stability, and optical tunable characteristics. AuNPs, such as gold nanorods or nanoshells,[@b42-ijn-11-5335] have optical properties of light absorbance and scattering in near-infrared (NIR) wavelengths (650--900 nm).[@b43-ijn-11-5335] The therapy with NIR laser and AuNPs was effective in cancer cell lines in vitro.[@b44-ijn-11-5335],[@b45-ijn-11-5335] AuNPs could act as contrast agents by microscopy for the diagnosis for cancer. For instance,


medicine as prescribed, annual medical spending is reduced by almost $9,000 per patient with congestive heart failure, more than $4,000 per patient with hypertension or diabetes, and about $2,000 per patient with high cholesterol.

In many cases, patients may intend to take their medicine but forget or get confused, says Pascal Imperato, dean of the School of Health at SUNY Downstate in Brooklyn. Unintentional slipups are especially likely for elderly patients, those with cognitive decline or psychiatric disorders, and those who have to deal with multiple chronic conditions and may be taking several medications prescribed by different doctors. Affordability is another major hurdle. Study after study finds that the high cost of drugs and steep insurance co-payments prevent many patients from filling prescriptions and taking full dosages.

In some cases,Role of the compact node and its posterior extension in normal atrioventricular nodal conduction, refractory, and dual pathway properties.
The functional origin of AV nodal conduction, refractory, and dual pathway properties remains debated. The hypothesis that normal conduction and refractory properties of the compact node and its posterior nodal extension (PNE) play a critical role in the slow and the fast pathway, respectively, is tested with ablation lesions targeting these structures. A premature atrial stimulation protocol was performed before and after PNE ablation in six isolated rabbit heart preparations. Discrete (approximately 300 microm) histologically controlled PNE lesions amputated the AV nodal recovery curve from its left steep portion reflecting slow pathway conduction and prevented reentry without affecting the right smooth fast pathway portion of the curve. The ablation shortened


moment values also greatly increased after posttreatment with formamidopyrimidine-DNA glycosylase (Fpg). This suggests that in human cells PAT is a potent clastogen with the ability to cause oxidative damage to DNA. However, no significant change in the tail moment values in CTN-treated cultures was found, suggesting that CTN is not genotoxic to HEK293. Incubation of HEK293 with CTN increased the mRNA level of heat shock protein 70 (HSP70), but not that of human 8-hydroxyguanine DNA glycosylase 1 (hOGG1). PAT treatment did not modulate the expression of either HSP70 or hOGG1 mRNA.Old and Middle Kingdom periods. All Egyptian pyramids were built on the west bank of the Nile, which as the site of the setting sun was associated with the realm of the dead in Egyptian mythology. The Pyramids contain a maze of passage ways, designed to protect the Mummies of the Pharaohs and the treasure which they would take to the afterlife.

Karnak & Luxor Temples

Second in popularity only to the iconic pyramids, the temples of Karnak and Luxor are some of the most striking relics of ancient history in the world. The Karnak complex is made up of four distinct sections, of which only the Amun-Re precinct is open to the public. The Amun-Re part of the complex consists of numerous, intricate temples, columns and an obelisk. The


!= null)
    {
        Exception ex = (Exception)HttpContext.Current.Cache["LastError"];
        if (ex.Data["ErrorTime"] != null && ex.Data["ErrorSession"] != null)
            if ((DateTime)ex.Data["ErrorTime"] > DateTime.Now.AddSeconds(-30d) && ex.Data["ErrorSession"].ToString() == Session.SessionID)
                Label1.Text = ex.InnerException.Message;
    }
}

Of issue: I don't want to do a Server.Transfer from Global.asax because.. I don't know. Seemed clumsy to me. Want to be able to change customErrors to RemoteOnly. So have to save last exception somewhere, but can't be Session, so save to Cache but with some extra data (time and SessionID) since Cache is global andwant to make sure not showing wrong error to someone.

I changed my code somewhat. Now it's just:
void Application_Error(object sender, EventArgs e)
{
    HttpContext.Current.Cache["LastError"] = Server.GetLastError().GetBaseException();
    Server.ClearError();
}

...and...
protected void Page_Load(object sender, EventArgs e)
{
    if (IsPostBack) return;

    if (HttpContext.Current.Cache["LastError"] != null)
    {
        Exception ex = (Exception)HttpContext.Current.Cache["LastError"];
        if (ex != null)
            Label1.Text = ex.Message;
    }
}

Note SessionID not there if anonymous user, and ex.Data.Add a key that's already there will cause error making me realize it's important to call ClearError

A:

I think that's a decent way to do it.  It's not


Mark Cuban is an ideas man, and he's got a hell of an idea. In late November, Cuban announced that he had asked the NBA Board of Governors to consider letting injured players use synthetic human growth hormone (HGH) while rehabbing and that he was willing to fund the necessary clinical studies to ensure player safety himself. I was intrigued, and I wasn't the only one.

"They're open-minded," Cuban said, referring to the Board of Governors. "Knowing that it'll take 10 years to get [the studies] done, it's easy to be open-minded and say when it's there, it's there. But hopefully it's something I can accelerate. I've talked to a couple of different universities about funding studies."

Cuban compared HGH use to Tommy John surgery, in which the ulnar collateralthere assigned 103 recreational athletes ages 18 to 40 into four treatment groups: 1) HGH, 2) Testosterone, 3) HGH with testosterone, or 4) Placebo. The study found that HGH users saw a 4-5% increase in speed on a bicycle, while testosterone users had an 8% increase. The study, which was funded by the World Anti-Doping Agency, also found that in a hundred meter dash, sprinters using HGH had a 0.4-second improvement in their times. (These figures will obviously shift based on where an athlete is as they begin using HGH.) Understandably, HGH remains banned from competitive sport; it simply provides an unfair competitive advantage, allowing athletes to achieve feats that weren't previously attainable. Think of it as Testosterone Lite.

How does it help heal?

But what about injured athletes—athletes like


pressas mot cementgolvet som hon låg på. Den sidan var _ner. Upp_ var den grova madrass som hon krupit in under vid det sista avbrottet av starkt, bländande ljus. Huvudvärken var borta nu och den enda verkliga smärtan satt i fingrarna på den vänstra handen. Ringfingret var brutet, det visste hon.

Hon hade en täckjacka på sig som hon inte kände igen. Den var ren och luktade mjukmedel. Golvet var också rent så när som på de kycklingben och grönsaksrester som hennes fångvaktare hade rakat ner genom hålet. De enda övriga föremål som fanns nere hos henne var madrassen och en toaletthink med ett snöre fäst vid handtaget. Det kändes som ett bomullssnöre och det fortsatte uppåt i mörkret så högt hon kunde nå.

Catherine Martin kunde röra sig fritt,i storlek 40, och där fanns också några Reeboks och några loafers. En lätt ryggsäck och en tennisracket låg på översta hyllan.

Saker som tillhörde en privilegierad flicka, en student och lärarpraktikant som levde bättre än de flesta.

Det låg fullt med brev i sekretären. Lustiga, tvetydiga brev från gamla klasskamrater österut. Frimärken, adressetiketter. Presentpapper i nedersta lådan, en hel bunt i olika färger och mönster. Starling kände på dem med fingrarna. Hon funderade på att prata med något biträde i den lokala drive-in-butiken när hennes fingrar stötte på en rulle i högen av presentpapper som kändes för tjock och för hård. Hennes fingrar gled över den och så tillbaka igen. Hon var tränad i att reagera för allt som var avvikande och hon rullade ut den till hälften och


följde också med. En bonde som var lutheran ställde upp med hö. Man hade redan ett stall på hemmet. Vi plöjde trädgården med henne. Men man måste se upp med var hon gick. Hon kunde gå rakt genom spaljén med vaxbönor och trampa på alla plantor som var så låga att hon inte kunde känna dem mot benen. Och vi ledde henne runt och lät henne dra barn i en kärra.«

»Men så dog hon?«

»Ja.«

»Berätta om det.«

»Det hände förra året. Man skrev till mig från skolan. De trodde att hon var omkring tjugotvå år. Hon drog en kärra full med ungar sista dagen hon levde och hon dog i sömnen.«

Doktor Lecter tycktes besviken. »Så rörande«, sade han. »Låg er fosterfar i Montana med er, Clarice?«

»Nej.«

»Försökte han?«

»Nej.«

»Vad var det somni dem?«

Hon nickade. »De... förde ut mig ur arresten. De uppträdde helt korrekt.« _Pembry som kom runt Chilton, generad, beslutsam men artig. Följ med mig nu, sa han. Han hade leverfläckar på händerna och i pannan. Död nu, blek under leverfläckarna._

Plötsligt måste Starling ställa ifrån sig kaffet. Hon fyllde lungorna med luft och såg upp i taket. »Hur bar han sig åt?«

»Han kom undan i ambulansen, sa Copley. Vi ska undersöka det. Vad fick ni fram om LSD:et?«

Starling hade tillbringat eftermiddagen och en del av kvällen med att analysera bladet med Plutofigurer i enlighet med Krendlers order. »Ingenting. Man försöker med läkemedelsregistren för att se vem som tillverkat det, men det är tio år gammalt. Man kan kanske få fram mer genom själva trycket än vad Läkemedelsinspektionen kan


mot fotsvett i sina sandaler. Snörhålen var uttänjda i hennes gymnastikskor.

Kanske Fredrica brukade motionera – hon hade några urvuxna joggingdräkter.

De var av märket Juno.

Catherine Martin hade också haft ett par stora byxor som var gjorda av Juno.

Starling gick ut ur garderoben. Hon satte sig med armarna i kors vid sängens fotända och såg in i den tända garderoben.

Juno var ett vanligt märke som såldes på många ställen där man sålde extrastora plagg, men det gav anledning till en fråga om kläder. Varje någorlunda stor stad hade minst en affär som specialiserade sig på kläder åt tjocka människor.

Stod Buffalo Bill på vakt utanför sådana butiker, valde ut ett offer och följde efter henne?

Gick han in i sådana butiker i damkläder för att se sig omkring? Alla butiker som säljerIn-situ growth of zeolitic imidazole framework-67 on nanoporous anodized aluminum bar as stir-bar sorptive extraction sorbent for determining caffeine.
The objective of the present study was to develop a simple, sensitive and cost-effective sample pretreatment technique to extract and determine caffeine in different samples of beverage as well as urine. An anodized aluminum bar was electrochemically prepared and employed as nanoporous substrate for in-situ growth of crystals of the zeolitic imidazole framework-67 (ZIF-67). The above-mentioned sorbent, too, was applied as a stir bar sorptive extraction (SBSE) device along with HPLC-UV. Under predetermined experimental condition, the detection limit of the aimed method was 0.05 μg L-1 in beverages, and it was 0.1 μg L-1 in urine samples. Moreover, the linear dynamic range was 0.2-200 μg L-1 for beverages, and it


A Seattle police officer has been caught on tape telling a recently arrested young African American man that he was going to make up evidence against him.

Josh Lawson and Christopher Franklin were arrested at gunpoint in November of 2010 after police spotted them several blocks away from where an assault had been reported. Neither man was charged with any crime after their arrest, and they have sued the city for excessive force and wrongful arrest.

ADVERTISEMENT

Both men allegedly suffered facial bruises after being kicked and thrown on the pavement as the police officers arrested them. While Lawson and Franklin were being taken to the police department, one of the officers also said he was going to make up evidence against them, an audio recording obtained KOMO 4 News revealed.

“Well,Suppose 5*v - 3*z = 40, -v - w*z + 16 = v. Is 8 a factor of v?
True
Let y(q) = 3*q**3 - q**2 - 34*q - 4. Does 46 divide y(8)?
True
Let j(v) = 19*v**2 - 10*v - 9. Is j(5) a multiple of 20?
False
Let i = 16 - 20. Let y(w) = w + 9. Let v be y(i). Suppose 0 = v*f - 165 + 25. Is 7 a factor of f?
True
Suppose 0 = -25*h + 10*h + 450. Does 10 divide h?
True
Let u = 107 + -128. Let j(m) = m**2 + 10*m + 5. Let k be j(-6). Let l = k - u. Is 2 a factor of l?
True
Let n = 148 - -428. Is 16 a factor of n?
True
Suppose -23*a = -15*a


(IFN-*γ*), tumor necrosis factor-*α* (TNF-*α*), IL-17, and IL-22, can induce inflammatory molecules and angiogenic factors in keratinocyte and alter their differentiation pathway \[[@B5], [@B10]\]. These events lead to the cutaneous expression of the disease which consists in large erythematous desquamative plaques. However, psoriasis is frequently associated with the development of arthritis (PsA), due to focal bone erosion and repair processes consequent to inflammatory involvement of peripheral or axial joints \[[@B11], [@B12]\]. A key role in development of psoriatic lesions appears to be due to the expression of homing receptors by activated T cells, facilitating their migration to the skin \[[@B13]\]. Among them, the cutaneous lymphocyte-associated antigen (CLA), an epitope generated by fucosyltransferase-VII mediated modification of P-selectin glycoprotein ligand-1, which binds to E-selectin on vascular endothelium in the skineffector cells belonging to either the innate or the adaptive immune system and is capable of amplifying the response of both systems with pleiotropic modalities \[[@B17]\]. This notion is reinforced by the results of clinical trials based on the administration of anti-TNF-*α* therapy in patients with psoriatic arthritis \[[@B18]--[@B21]\]. A further link between altered immunologic circuitries, lymphocytes infiltration, and epidermal hyperplasia has been provided by recent studies which show that T cells expressing IL-17 may play a major role in psoriasis \[[@B22], [@B23]\]. This pathological immune circuitry appears driven by interleukin-23 \[[@B24]\]. In mice, injection of IL-23 leads to epidermal hyperplasia mediated by IL-22 which, in turn, is produced by IL-17-expressing T cells \[[@B25]\]. A similar scenario is suggested by study in humans \[[@B26], [@B27]\]. On the other


hand, an impairment of regulatory T lymphocytes (Treg) may play a pivotal role in the pathogenesis of the disease. In fact, the balance between regulatory and effector functions is important for maintaining efficient immune responses, while avoiding autoimmunity. Indeed, the hyperproliferation of pathogenic effector T cells in psoriasis has been associated with either a reduction or a functional impairment of blood and tissue Treg cells \[[@B28], [@B29]\].

The therapeutic approach to psoriatic patients is based on two major categories of drugs, namely, the conventional immunosuppressive drugs (i.e., methotrexate cyclosporine) or acitretin and the last generation biological agents. In addition to TNF-*α* antagonists such as infliximab (a chimeric monoclonal antibody composed of a human IgG1 constant region and a murine variable region), etanercept (a soluble TNFR, made of two extracellularblood of psoriasis patients before and during therapy with etanercept (a), adalimumab (b), and infliximab (c). Measurements were compared by one way ANOVA for repeated measures, nonparametric test. Depicted values are median and interquartile ranges.](MI2014-236060.005){#fig5}

![Lymphocyte proliferation toward*Candida albicans* and CEF antigens as performed at baseline (T0) and after 24 weeks of treatment (T2) in a representative group of 30 patients under therapy with etanercept (10), adalimumab (10), or infliximab (10). Stimulation indexes of CD4+ (a) and CD8+ (b) lymphocytes.](MI2014-236060.006){#fig6}

######

Clinical characteristics of patients and treatments.

  -------------------------------------------------------------------
  Therapy (patients)   *T*        PASI 50\    PASI 75\    PASI 90\


from the carbon backbone. In the case of the molecules bound directly to gold, these eigenstates are the HOMO and LUMO of a reduced system (terminal atoms removed). However, when we consider the system with binding groups, these orbitals are not necessarily the HOMO and LUMO of the full system and a reader should keep this in mind.

In Fig. \[tau\_tc0\], a relatively strong coupling between the chain and the gold is assumed. As $t_{Au-bind}$ decreases the transmission in the HOMO-LUMO gap develops more structure as can be seen in Fig. \[bindinggroup\] a). Here $\tau(E)$ is shown for chains with $\ell=10$ and parameters the same as in Fig. \[tau\_tc0\] except for $t_{Au-bind}=-1$ eV and $E_{bind}=-1$ eV. When $\Gamma=t_{Au-C}=1$ eV, two peaks are observed around $E=0$. As $\Gamma$ increases to $4$ eV only the lower peak remains.on how one can break down the encryption protections on Android smartphones powered by Qualcomm Snapdragon processors.

Basically, Android's disk encryption on devices with Qualcomm chips based only on your password. However, in real, Android uses your password to create a strong 2048-bit RSA key (KeyMaster) derived from it instead.

Qualcomm runs in the Snapdragon TrustZone to protect critical functions like encryption and biometric scanning, but Beniamini discovered that it is possible to exploit an Android security flaw to extract the keys from TrustZone.

Qualcomm runs a small kernel in TrustZone to offer a Trusted Execution Environment known as QSEE (Qualcomm Secure Execution Environment) that allows small apps to run inside of QSEE away from the main Android operating system. KeyMaster is also a QSEE app.

The researcher has detailed how attackers


can exploit an Android kernel security flaw to load their own version of QSEE app inside this secure environment, thereby exploiting privilege escalation flaw and hijacking of the complete QSEE space, including the keys generated for full disk encryption.

Once getting hold of this key, an attacker could perform a brute-force attack to grab the user password, PIN or lock, cracking Android's full disk encryption.

Moreover, Qualcomm or OEMs can comply with government or law enforcement agencies to break the FDE.

"Since the key is available to TrustZone, Qualcomm, and OEMs [Original Equipment Manufacturers] could simply create and sign a TrustZone image which extracts the KeyMaster keys and flash it to the target device," Beniamini wrote. "This would allow law enforcement to easily brute force the FDE password off the devicegoaltender and he played well."

LSSU (6-4-0, 4-4-0-0 WCHA) was called for a penalty late in the game and L'Esperance added to the lead with 1:14 left on the clock. Mark Auk fed it over to L'Esperance for the one-timer and his 27th career goal.

"Joel is doing some things away from the puck better and that's translating into his offensive game," Pearson said. "Tonight is only going to help his confidence because he's an important player for us."

Angus Redmond improved to 5-1-0 between the pipes for the Huskies with 18 saves, making six saves in each period. Defiel stopped 43-of-47 shots for the visitors.

"Angus was sharp again tonight," added Pearson. "Our defensemen are doing such a good job limiting shots on our goal. Angus has been in a number


the smallest value?  (a) 1/5  (b) -6  (c) 6  (d) 0.3  (e) 2/3  (f) -4
b
What is the fifth biggest value in -22/15, 7, 3, 0, -2/11?
-22/15
Which is the fourth smallest value?  (a) -2539  (b) 2/9  (c) -2/17  (d) -1/3  (e) -4
c
Which is the smallest value?  (a) -35/181  (b) 3/7  (c) 4
a
Which is the fifth biggest value?  (a) -1/6  (b) 4  (c) -17  (d) 0  (e) 8  (f) 1/2
a
Which is the second biggest value?  (a) -9  (b) -0.03  (c) -2033
a
What is the smallest value in -3/7, 230, -0.7, -1/4, 0.5, -0.4?
-0.7
Which is the biggest value?  (a) 1/24  (b) 130  (c) 0.5
b
Which is thesome colorful Edison bulbs, and this pallet made bar was a real source of surprise for my friends. They really enjoyed and loved being served on it in the night time.

This Pallet Bar is created by: slorgegridlock


of this breaking to be above that of the inflation reheating, thus imposing constraints on both cosmological as well as particle physics aspects of models.

In practical construction of models with spontaneous CP breaking, one must have one or more Higgs fields to have complex vevs[@lee]. It is obvious that implementing this requires extending the standard model, by having either more Higgs/or fermion fields plus Higgs because gauge invariance allows no room for Higgs vevs to be complex in the standard model. Furthermore, since spontaneous CP violation (SCPV) requires nontrivial constraints on the realistic gauge models, it is not surprising that the process of implementing it can lead to unpleasant side effects. One such unpleasant effect is the plethora of flavor changing neutral current (FCNC) effects induced in theIt is clear that although CP is spontaneously broken at a high scale $\Lambda$, at low energies, one has CP explicitly softly broken [@rebelo] by the bilinear terms in $\lambda_{12}$. Note that both the fields $\phi_{1,2}$ have Yukawa couplings and we can make a redefinition of the phase of one of the doublet fields (say $\phi_2$) i.e. $\phi_2\rightarrow
e^{-i\beta}\phi_2$ so that all the bilinear and $O(\Lambda^2)$ terms in the potential become phase independent but the Yukawa couplings become complex. Thus the effective theory at low energies looks naively like hard CP violation, even though it is spontaneous CP violation at a very high scale. The Yukawa coupling Lagrangian looks like $$\begin{aligned}
{\cal L}_Y~=~\bar{Q}_{La}(h^{u,1}_{ab}\phi_{1}~+~
h^{u,2}_{ab}e^{-i\beta}\phi_{2})u_{R,b}+
\bar{Q}_{La}(h^{d,1}_{ab}\tilde{\phi}_{1}~+
h^{d,2}_{ab}e^{i\beta}\tilde{\phi}_{2})~d_{R,b}+ h.c.\end{aligned}$$ This still does not imply a viable complex CKM matrix; to achieve that, we must


\frac{R}{v}\\ \nonumber
+i\left[\bar{u}(N_uP_R-N^\dagger_uP_L)u-\bar{d}(N_dP_R-N^\dagger_dP_L)d
\right]   \frac{I}{v}\end{aligned}$$ where $$\begin{aligned}
H~=~\frac{1}{v}\left[v_1R_1+v_2R_2\right]\\ \nonumber
R~=~\frac{1}{v}\left[v_2R_1-v_1R_2\right]\\ \nonumber
I~=~\frac{1}{v}\left[v_2I_1-v_1I_2\right] \end{aligned}$$ with $\phi^0_1~=~\frac{1}{\sqrt{2}}\left[v_1+R_1+iI_1\right]$ $\phi^0_2~=~\frac{1}{\sqrt{2}}e^{i\delta}\left[v_2+R_2+iI_2\right]$. where $$\begin{aligned}
N_d~=~U^\dagger_{dL}\left[\frac{v_2}{\sqrt{2}}Y^d_1-\frac{v_1}{\sqrt{2}}
e^{i\delta}Y^d_2\right]U_{dR}\end{aligned}$$ where $U_{d_{L,R}}$ are the unitary matrices which diagonalize the down quark mass matrix $M_d$. Analogous expressions are there for $N_u$. It is clear that $N_{d,u}$ are in general not diagonal and therefore $R$ and $I$ mediate FCNC.

The quark mass matrices are in the form $$\begin{aligned}
M_dM^\dagger_d~=~H_{real}+
2iv_1v_2sin\delta(Y^{d2}{Y^{d1}}^T-Y^{d1}{Y^{d2}}^T)\end{aligned}$$ where $H_{real}$ is a symmetric real matrix. It is clear that $M_dM^\dagger_d$ (and similarly $ M_uM^\dagger_u$) is an arbitray complex matrix and therefore CKM is a complex matrix.

If one fine tunes such that $Y^d_1 \propto Y^2_d$, $N_d$ would be diagonal and FCNC would be eliminated. But in that case, Eq(34) implies that $M_dM^\dagger_d$ becomes real. This illustrates the connection between FCNC and the possibilitycould easily be replaced; and (4) his sentence should not have been enhanced for reckless endangerment. Because we reject each of these arguments, we affirm.

I.  Background

2
This case is before us for the second time. The first time, we held that Judge Brian Barnett Duff had "denied the government a fair suppression hearing" and remanded the case for a new hearing. See United States v. Watson, 87 F.3d 927, 928 (7th Cir. 1996) ("Watson I"). On remand, the case was transferred to Judge Ann Williams, who conducted a new suppression hearing and granted Watson's motion to suppress his confession. However, on reconsideration, Judge Williams vacated her earlier order and found that the confession was admissible.

3
The facts underlying the suppression controversy, as well as the rest of this appeal,


government filed a response signed by Krulewitch. Watson filed a motion to strike the government's response on the grounds that it was improper for Krulewitch to be involved in the case after he had testified as a witness at trial. The district court denied the motion to strike.

10
In a written opinion dated August 7, 1997, the district court found that the amount of loss attributable to the robbery exceeded $250,000, and that the reckless endangerment enhancement was warranted. However, the court declined to apply the obstruction of justice enhancement, finding that it was unclear whether Watson's false statements during the suppression hearings had been made with a willful intent to obstruct justice. On August 11, the government filed a motion, again signed by Krulewitch, in which it pointedDetermination of ethyl carbamate in distilled alcoholic beverages by gas chromatography with flame ionization or mass spectrometric detection.
Quantitative methods are detailed for determination of ethyl carbamate in distilled alcoholic beverages by capillary gas chromatography with flame ionization detection (GC/FID) and by packed-column gas chromatography/mass spectrometry (GC/MS) using selected ion monitoring. Five g samples of distillate of known ethanol concentration are diluted with water to 25% ethanol (v/v), washed with petroleum ether, and extracted with dichloromethane prior to GC/FID or GC/MS analysis. As necessary, sample extracts that exhibit GC/FID interference are passed through alumina for additional cleanup. When internal standards (tert-butyl carbamate and n-butyl carbamate for GC/FID, or ethyl 13C-15N-carbamate for GC/MS) were used for quantitation, the limit of detection for ethyl carbamate was in the range of 5-25


diagnosis.

PROFET™ stands for protected MOSFET and the product family includes all High Side switches, whether they are automotive qualified or designed for the needs of industrial applications. PROFET™ intelligent power switches consist of DMOS power transistor and CMOS logic circuitry for complete built-in protection. They are highly integrated load switches and incorporate a broad range of smart features, including diagnosis and protection.

All PROFET™ sub-families offer protection against overload, overvoltage, short-circuit, excessive temperature, ground loss, power supply loss and Electrostatic Discharge (ESD). Additionally, depending on the applications they were designed for (automotive, industrial, consumer, transportation and commercial vehicles ...), the PROFET™ load switch subfamilies can also protect against dynamic overvoltage such as load dump and inductive load turn-off.

SPIDER products are highly integrated multichannel SPI driver for small current loads,Impact of comorbidities on hospitalization costs following hip fracture.
Hip fractures are common in the elderly, and patients with hip fractures frequently have comorbid illnesses. Little is known about the relationship between comorbid illness and hospital costs or length of stay following the treatment of hip fracture in the United States. We hypothesized that specific individual comorbid illnesses and multiple comorbid illnesses would be directly related to the hospitalization costs and the length of stay for older patients following hip fracture. With use of discharge data from the 2007 Nationwide Inpatient Sample, 32,440 patients who were fifty-five years or older with an isolated, closed hip fracture were identified. Using generalized linear models, we estimated the impact of comorbidities on hospitalization costs and length of stay, controlling for patient, hospital,


Web sites are having a field day with this one.

3. Most embarrassing of all is the site where the beating-robbery-stripping occurred: in front of the Clarence Mitchell Jr. Courthouse.

Mitchell was a Baltimore civil rights icon, a member of the NAACP who was the organization’s lobbyist in Washington. He was so instrumental in influencing congressmen to vote for civil rights legislation that he earned the nickname “The 101st Senator.”

He was a man of dignity and grace. Last month a group of so-called black folks with neither dignity nor grace desecrated the courthouse named for him.

Time for me to grab that bag. Readers now know that I’m from Baltimore. I have only one request.

Please, don’t spread that around.

—

Gregory Kane is an award-winning columnist and Pulitzer finalist who writes from Baltimore.of modern parenthood." "Bouncy chair, three-compartment diaper bag assorted books and toys, all certified nontoxic and educational." "Oh, get a look at this:" "Electric bottle warmer." "So how'd the meeting with the lawyer go?" "Very well, very well." "We've been approved as temporary guardians." "Attorneys say that if they're not able to find Kathy within 90 days we have a good chance of being awarded permanent custody." "We wouldn't even have to formally adopt." "She could come back, you know." "Yeah, I'm aware of that." "But you try not getting attached to this little angel." "Mother, what is all this?" "Packing." "I can see that, but it seems like an awful lot for a vacation." "It's not for a vacation." "I'm moving to Africa." "Gonna shack up with


her head." "HARRY:" "Okay, I will, yeah." "Love to you too, sweetheart." "Unbelievable." "What is it, dear?" "Mother never called Linda  nor is my sister expecting her any time soon." "No, the woman blatantly lied to me." "Maybe she hasn't got around to calling yet." "Oh, no, no, no, she was on her way." "Her bags were packed." "Obviously, my mother was making up the entire thing." "The question is why." "Maybe she met someone." "That's crazy." "It's only been two weeks." "It's happened before." "Oh, indeed." "The funeral baked meats did coldly furnish forth the marriage tables." "There's no need for Shakespeare, dear." "We get the point." "It would explain why she's so embarrassed to tell the truth." "ROSE:" "Do you see what I have toamazing faculty, complete scholarship my mom's totally excited about it." "Plus, it's far away from my ex-boyfriend." "Yeah, El Jerko?" "El Jerko, right." "Well, it would just be a lot easier to get over him fully." "Okay, so those are some okay pros." "Now what about AM?" "Okay." "Um...." "I like the campus." "Beautiful campus." "Yes." "Mm-hm." "Uh...." "Mm-hm." "And I'd get to dorm with Amy, which would be fun." "And...." "What, that's all?" "Stop it." "It's got a great Sociology program, so it's not like I'd be getting a terrible education but, I mean, nothing like Notre Dame." "Seriously." "[HANNAH sighs]" "Really, the only reason I'm considering it is because you guys are here." "Well, yeah, sure." "Which is a huge pro, you know?" "It's" " It


what my life is anymore." "So let us help you, Mother." "That's what we've been trying to do." "I know you want to, but you can't." "No one can." "I just need to be alone right now." "That's your plan, then?" "Just get in the RV and drive around all by yourself for a month or so?" "I couldn't say for how long." "Frankly, without Harper I don't see myself going much longer anyway." "Mother, well, now you are acting crazy." "You have plenty of time left." "You have a family who wants to take care of you." "I have never been taken care of in my lifetime and I don't intend to start now." "I'm not gonna be a burden." "Not to you or Rose or anyoneelse." "Mother." "Please don't try to talk me out of this." "It was a tough decision, but I've made up my mind." "I'm going." "Amy, you haven't moved for over two hours." "Are you sick, sweetheart?" "No, I'm stupid." "I had the thing, Mom." "I had the thing that everybody wants, and I threw it away." "And now Ephram has become Stephram." "You can't go up to Stephram and be like:" ""Hi, I'm in love with you again." Especially since she's buying him jackets." "Okay." "She's working it from the inside." "She has home-court advantage." "I thought I could work the old-school angle but now I'm realizing that I have no angle." "All I have is how I feel, and I can't describe how I feel, because it's


a line of the table-file it
prints a warning message on its standard output and goes on to
the next line in the table-file without performing any of the actions
specified by the erroneous rule.

If it cannot create a link for some filesystem-related reason it prints
an error-message and continues with the current rule.

If it cannot read necessary data it prints an error message and
continues with the next table-file line.

Examples

Example 1 Using the /etc/devlink.tab Fields

The following are examples of the /etc/devlink.tab fields:

type=pseudo;name=win win\M0
type=ddi_display framebuffer/\M0 fb\N0

The first example states that all devices of type pseudo with a
name component of win will be linked to /dev/winx, where x is
the minor-component of the devinfo-name (this is always a single-digit number for the
win driver).

The second example states that all devinfo nodes of type ddi_display will
be linkedlike running in this year's zombie 5k in my hometown of Charlottesville, VA isn't in the cards for me. Initially, I thought it would be a convenient jaunt as we're going to be in northern Virginia that weekend for a family event, but between the University of Virginia having family weekend, thus filling the area hotels, and some UFC pay-per-view event the night before that my husband simply can't miss (thus ruling out a stay at my mom's cable-free house) it looks to be more trouble than it's worth. Besides, why add an extra four-hour drive to our trip just so I can do a 35-minute run? At least that's what I'm trying to tell myself when I get all teary eyed at the thought of missing it.


only surprised me with a delicious meal at a fancy restaurant and a yummy marzipan-covered cake, but they also gave one of the best birthday presents I've ever gotten. I can't tell you how shocked I was when I opened my wonderful gift. To understand how thrilling this acquisition is to me, allow me to share the saga of my quest for a Jo Totes bag:

A long time ago in a galaxy pretty much exactly where I am now, I started seeing giveaways for a pretty camera bag making the rounds in the blog world. The bag is not only sturdy with padded inserts that can be rearranged to suit one's camera configuration, but it's also absolutely adorable. It comes in all sorts of trendy colors and stylesit’s not sticking. If it seems to be snapping back, cover it with your damp towel and let it rest for 5 minutes before continuing (I had to do this twice during the process).

Spread the browned butter over the surface of the dough with a pastry brush and then sprinkle the sugar mixture over the top, patting it down to ensure it mostly sticks. Joy the Baker encourages you to use it all even though it seems like a ton, but I admit I got squeamish at the amount and only used most. It was fine despite my nerves. Go ahead and pile it on.

With the long edge of the rectangle toward you, cut it into 6 strips (do this by cutting the rectangle in half, then cutting