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                \begin{document}$$R_t$$\end{document}$ \[[@CR9]\].

If data-based forecasts are the primary scope, it seemed reasonable to us developing a hybrid approach: a simple dynamic model that can be easily tuned with available data. This goal is obtained with our approach based on a single prognostic variable, which is found to satisfy an ordinary integro-differential equation.

To our knowledge, there are only a few approaches that are equally simple and effective. In \[[@CR10]\] a delay model is presented with a single prognostic equation that has even \usepackage{amsfonts}
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                \begin{document}$$\varDelta P_n$$\end{document}$ on day *n* and the weighted sum of new cases on the previous $\documentclass[12pt]{minimal}


               \begin{document}$$\{{\widetilde{R}}_j\}_{j=N_r}^n$$\end{document}$, thus providing us with a law, purely based on data, on how this epidemic variable evolves. The data we observed show that, prior that restrictive measures have been adopted, $\documentclass[12pt]{minimal}
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                        \begin{document}$${\widetilde{R}}_n$$\end{document}$ are strongly smeared out, we simply model data by one single step with an asymptotic decay. Obviously, in order to gain higher accuracy, *R*(*t*) could be described with a more complicated, piece-wise defined function but at the price of introducing additional fitting parameters. The time $\documentclass[12pt]{minimal}
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                \begin{document}$$\gamma = 1/T_r$$\end{document}$, $\documentclass[12pt]{minimal}
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                \begin{document}$$R_0$$\end{document}$, *S*(0) and *N*, are subsumed into a single function *R*(*t*), which is obtained from real data, without having to speculate on how it comes about. This makes the model simple---and setting the weights constant---even simpler so that it can be set up quickly to produce satisfying prognoses.From the comparison with the compartmental SIR models, we see that our epidemiological variable *R*(*t*) assume the meaning of *generalized effective reproduction number* associated with the infectivity probability *g*(*t*), which is typical of the disease.With these assumptions we have been able to


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                \begin{document}$$I(t) = 0$$\end{document}$.

Discussion of model results {#Sec6}
===========================

Data for the COVID-19 epidemic are made available by the John Hopkins University \[[@CR25]\] and coincide, at least for Italy and Germany, with those from Worldometers \[[@CR26]\]. The original time series data show significant weekly fluctuations, hence we only work with 7-day averages, which acts as a low-pass filter.

Italy {#Sec7}
-----

Fig. 2Left: $\documentclass[12pt]{minimal}
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                \begin{document}$${\widetilde{P}}_n$$\end{document}$. Note that the last model-tuning was made on April 13, 2020. Two weeks later the relative deviation of the cumulative number of cases is about $\documentclass[12pt]{minimal}
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                \begin{document}$$N_r = 11$$\end{document}$ days.

The effective reproduction number *R*(*t*) is shown for the time period from March, 3 to April, 14. The most restrictive measure in Germany was the school closing on March, 14. Note that some days before the $\documentclass[12pt]{minimal}
              April 28, 2020.Table 1Fitting parameters for the effective reproduction number *R*(*t*)Country$\documentclass[12pt]{minimal}
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               frank or symptomatic hyperglycemia. Two research projects are investigating epithelial water and electrolyte transport with the long term objective of understanding the pathophysiology of the exocrine electrolyte abnormalities of CF. One of these projects using rat parotid retrograde perfusion assay, has found that polyamine-derived polycations isolated from CF seminal plasma inhibit sodium transport. Polycations with similar properties have been isolated from CF saliva. This project has had a change of emphasis toward polyamine catabolism in human exocrine glands. The second basic research project is investigating cellular mechanisms of epithelial electrolyte transport and has demonstrated that sodium transport inhibitors from CF saliva will inhibit short-circuit current in the rat colon. Contrary to reports from another laboratory (Araki, et al., Pediat. Res., 9:932, (1975), CF serum does not inhibit glucose


work, much in continuation of that of Refs.[@JimPhD; @Congleton].

This paper considers the ordinary nuclear muon capture process on a spin 1/2 isospin doublet in terms as general as is possible. Not only are all possible effects existing within the SM included in the present analysis, but any possible contributions which may appear beyond the SM due to new interactions are accounted for as well through an effective four-fermi quark-lepton interaction which describes all possible scalar, pseudoscalar, vector, axial and tensor couplings. Indeed, given the momentum transfer involved, much less than any of the mass scales characterizing such possible interactions, an effective four-fermi interaction at the quark-lepton level is perfectly justified.

Previous analyses over the years, beginning with Ref.[@Bernstein] pointing out the existence of the hyperfine effect in the capturethe (proton,neutron) doublet do indeed bear out such an expectation[@Donoghue; @Holstein2; @Dominguez; @Shiomi]. In the same manner, one could wonder about the effects of isospin symmetry breaking for the $F_V$ and $F_M$ form factors obtained through CVC. In this particular case, thanks to the Ademollo-Gatto theorem[@AG], isospin breaking corrections are only of quadratic order in the ratio $(m_d-m_u)/\Lambda_{\rm QCD}$, hence negligeable for our purposes. Let us also recall that CVC has been very well established through precision studies in $\beta$-decay[@CVC], and that even though limits exist on second-class form factors from correlation experiments in $\beta$-decay, the stringency of these constraints are nowhere close to the theoretically expected values for $g_S$ or $g_T$[@PDG].

In the matrix elements for the scalar, pseudoscalar and tensor quark operators, we have chosen not to


           \end{array}\right)\ \ ,\ \
\chi_-(\hat{s})=\left(\begin{array}{c}
        -e^{-i\varphi/2}\sin\theta/2\\
        e^{i\varphi/2}\cos\theta/2
            \end{array}\right).
\label{eq:chifunctions}$$

Finally in the case of solutions to the massless Dirac equation, “positive" and “negative" energy plane wave solutions of helicity $\lambda=\pm 1$ and momentum $\vec{k}$ are given by $$u(\vec{k},\lambda)=\sqrt{k^0}\left(\begin{array}{c}
            \chi_\lambda(\hat{k})\\
            \lambda\chi_\lambda(\hat{k})
                \end{array}\right)\ \ ,\ \
v(\vec{k},\lambda)=\sqrt{k^0}\left(\begin{array}{c}
           {\rm MeV}\ \ &,&\ \ \omega=2810.82\ {\rm MeV}\ \ &,&\ \
\omega-M_2=1.90\ {\rm MeV}.
\end{array}$$

As explained in Appendix 1, the overlap reduction factor $C$ in this case takes the value $C=0.979$[@JimPhD; @Congleton], while the latest value quoted in Ref.[@PDG] for the CKM $ud$ mixing angle is used, namely[^10] $$V_{ud}=0.9750\pm 0.0008.
\label{eq:Vud}$$ This value results from a global fit which includes the constraints of unitarity of the CKM mixing matrix, rather than the value which would follow solely from the $0^+$-$0^+$ superallowed $\beta$-decay $ft$-values.

Values for the nuclear form factors at the relevant momentum transfer $q^2_1=-0.954m^2_\mu$ must also be specified. For this purpose, we refer to the discussion in Refs.[@JimPhD; @Congleton] and use the values advocated by these authors. For the electroweak vector and induced magnetic form factors, one has $$F_V(q^2_1)=0.834\pm 0.011\


\ ,\ \
F_M(q^2_1)=-13.969\pm 0.052.$$ The situation for $F_A(q^2_1)$ is somewhat more delicate, since only its value at $q^2=0$ is known from $\beta$-decay of $^3$H, while its $q^2$-dependency may only be inferred through a nuclear model calculation of the associated mean square charge radius[@JimPhD; @Congleton]. This leads to the following value $$F_A(q^2_1)=-1.052\pm[0.005-0.01],$$ where the interval for the uncertainty is an attempt to reflect the lack of precise knowledge of this form factor. The lower uncertainty of 0.005 stems from the uncertainties on the $^3$H $\beta$-decay rate, while the corrections due to mesonic exchange currents may only be estimated in the nuclear model calculation, leading to a total uncertainty of 0.007 on $F_A(q^2_1)$[@JimPhD; @Congleton]. Thus the bracket $[0.005-0.01]$ represents a conservative evaluation of the uncertainty on that form factor,$F_A(q^2_1)$.

Finally, the remaining two second-class form factors for the vector and axial quark operators, $F_S(q^2_1)$ and $F_T(q^2_1)$, are taken to be vanishing, even though for the reasons explained in Sect.\[Sect2.2\], one should expect that their absolute values, normalized to those for $F_V(q^2_1)$ and $F_A(q^2_1)$, respectively, would be on the order of 0.02. As will become clear later on, the statistical capture rate is in fact rather insensitive to these two form factors, so that this reasonable approximation is certainly sufficient.

These are all the nuclear form factors required when considering muon capture within the SM. Beyond that model however, the genuine nuclear scalar, pseudoscalar and tensor form factors, $G_S(q^2_1)$, $G_P(q^2_1)$ and $G_T(q^2_1)$, are also required. As mentioned previously, values for these quantities are not known, but are expected to


$h^V_{--}$ does not imply any limit on the mass $M^W_2$ of the extra charged gauge boson, since an expression similar to that given in Appendix 3 for the coefficient $h^V_{--}$ also applies to the similar coefficient $f^V_{--}$ relevant to $\beta$-decay, so that when reexpressing all couplings in terms of physical quantities (such as the muon decay rate, and so on), such factors essentially cancel. As a matter of fact, the sole contribution which survives this comparison of muon decay, $\beta$-decay and muon capture amplitudes, is that in LRSM the CKM leptonic flavour mixing matrices may be different for the electron and muon flavours. Thus in fact, the above limit on $h^V_{--}$ translates into the following constraint on leptonic flavour mixing in these two sectors, when the mixing angle$\zeta$ of the charged gauge bosons is ignored, $\zeta=0$[@Gov1], $$(v_\mu-v_e)v_ur^4\delta^2=-0.00018\pm 0.01424,$$ with $$v_\mu=\frac{\sum_i'|U^R_{\mu i}|^2}{\sum_i'|U^L_{\mu i}|^2}\ \ ,\ \
v_e=\frac{\sum_i'|U^R_{e i}|^2}{\sum_i'|U^L_{e i}|^2}\ \ ,\ \
v_u=\frac{|V^R_{ud}|^2}{|V^L_{ud}|^2},$$ in which the summation over the index $i$ stands for all neutrino mass eigenstates whose production is kinematically allowed in muon capture on the one hand, and in $\beta$-decay on the other (in which case, their mass is taken to be negligeable as well). The other parameters are defined in Appendix 3.

Similarly, the result on $h^V_{-+}$ in (\[eq:hexp3He\]) may be translated in terms of parameters of LRSM as (see Appendix 3), $$rt\,{\rm Re}\left(e^{i\omega} v_{ud}\right)=0.000222\pm 0.0176.$$ In the case of manifest LRSM with $r=1$, $v_{ud}=1$ and $\omega=0$, this result provides a limit on the mixing angle $\zeta$ which does not improve such limits stemming


the $S_{1/2}(-2/3)$ LQ with the couplings $\lambda^{L*}_{S_{1/2}}\lambda^R_{S_{1/2}}$. Thus in the above lower bound, $M$ stands for the mass of one or the other of these scalar LQ, while $\lambda$ stands for the square root of the product of the two associated couplings constants.

Similarly considering the limit in (\[eq:hexp3He\]) on the coefficient $h^S_{++}$, one finds the lower bound, $$\frac{M}{\lambda}>915\ {\rm GeV}\ \ (95\%\ {\rm C.L.}),$$ in a similar notation referring now to either vector LQ $V_0(-2/3)$ or $\tilde{V}_{1/2}(-1/3)$ (for the associated combination of LQ couplings corresponding to the factor $\lambda$, see Appendix 3). Again, these limits are certainly as stringent as those recently presented in Ref.[@H1; @D0]. This is particularly relevant when one recalls again that the constraints from Ref.[@H1] refer to the electron sector, while the limits establishedthese observables, which all involve either initial polarization muonic atom states or final polarization measurements, or both, poses an almost impossible experimental challenge. But such a situation has never deterred any experimentalist at heart, quite to the contrary! We hope that this paper will also be of use in the experimental pursuit of the impossible polarization observables.

Acknowledgments
===============

One of us (JG) wishes to thank Tom Case, Jules Deutsch, Peter Kammel, Claude Petitjean and Alexei Vorobyov for the many conversations we have had on the topics of this work over the last years. This work has been completed while each of the authors is enjoying a sabbatical leave from his home Institution. We wish to thank for their warm hospitality and support our present host Institutions, Peter van Nieuwenhuizen and


the C.N. Yang Institute for Theoretical Physics of the State University of New York at Stony Brook (USA), and the INFN National Laboratory at Frascati (Italy).

This work has been partially supported under the terms of an agreement between the CONACyT (Mexico) and the FNRS (Belgium).

Appendix 1: The Overlap Reduction Factor {#A1 .unnumbered}
========================================

In the calculation as outlined in Section 2, it is implicitly assumed that one is dealing with point-like particles whose quantum states are described by plane waves. Since this is clearly not the case, further corrections have to be introduced in order to account for the finite spatial extent of the nuclear charge distributions, for the bound state character of the initial muonic atom, and for possible relativistic corrections since it is the non relativistic Coulomb waveof the muon (“carrying" the reduced mass $\mu$ of the muonic atom) in the electrostatic field of the nucleus of finite size. In principle, this function is to be obtained by solving the associated Dirac equation in the given electrostatic potential, but one would expect that the ensuing relativistic corrections should be sufficiently small to be ignored since of order $(\alpha Z)^2$, which is the squared velocity of the bound muon. This expectation is indeed borne out by the detailed numerical resolution of the associated Dirac equation in the case of $^3$He[@JimPhD] and of the proton, and this relativistic correction shall thus not be included here in the evaluation of $C_m$.

Hence, this leaves only to solve the Schrödinger equation in the same electrostatic potential of the electric charge


is to indicate how results pertaining to these hyperfine states may be extracted from the results derived in Sect.\[Sect2\].

First, let us note that for a spin 1/2 system, any of its normalized quantum states may be parametrized as $$|\hat{s}>=e^{-i\varphi/2}\cos\frac{\theta}{2}\,|+>\,+\,
e^{i\varphi/2}\sin\frac{\theta}{2}\,|->,$$ where $|\pm>$ represent the basis of states with spin eigenvalues $m=\pm 1/2$ with respect to an arbitrary quantization axis. The angular variables $(\theta,\varphi)$ may be interpreted as being the spherical coordinates for a unit vector $\hat{s}$ whose components are defined as in (\[eq:spherical\]), since one finds for the associated spin component operators given in terms of the usual Pauli matrices $\vec{\sigma}$, $$<\vec{\sigma}>\equiv<\hat{s}|\vec{\sigma}|\hat{s}>=\hat{s}$$ (note also that the state $|\hat{s}>$ corresponds to the bi-spinor $\chi_+(\hat{s})$ in (\[eq:chifunctions\])).

Let us now consider the quantum spin states of a bound system of two spin,\ \
t=\tan\zeta\ \ ,\ \
v_{ud}=\frac{V^R_{ud}}{V^L_{ud}}\ \ ,\ \
\rho=\frac{g^2_L}{(M^W_1)^2}\,\cos^2\zeta\,V^{L}_{ud}.$$ Given the parametrization (\[eq:effec\]), one then finds for the only non vanishing effective coupling coefficients, $$\frac{g^2}{8M^2}V_{ud}\,h^V_{--}=\rho\left(1+\delta t^2\right)\,U^{L}_{\mu i}
\ \ ,\ \
\frac{g^2}{8M^2}V_{ud}\,h^V_{-+}=-\rho rt\left(1-\delta\right)e^{i\omega}
\,U^{L}_{\mu i}v_{ud},$$ $$\frac{g^2}{8M^2}V_{ud}\,h^V_{++}=\rho r^2\left(t^2+\delta\right)\,
U^{R}_{\mu i}v_{ud}\ \ ,\ \
\frac{g^2}{8M^2}V_{ud}\,h^V_{+-}=-\rho rt\left(1-\delta\right)e^{-i\omega}
\,U^{R}_{\mu i}.$$ Here, the indices $i=1,2,3$ and $\mu$ on the neutrino CKM matrix elements $U^{L,R}_{\mu i}$ stand for the neutrino mass and muon flavour eigenstates, respectively.

Let us now turn to the parametrization of so-called contact interactions, which provide a simple-minded model to probe the scale for compositeness of quarks and leptons. Such interactions are typically represented through an effective four-fermi coupling of the form[@PDG], say in the case of vector operators, $$4\epsilon_{\eta_1\eta_2}\frac{g^2_c}{8\Lambda^2}
\overline{\psi}\gamma_\mu P_{\eta_1}\psi\,
\overline{\psi}\gamma^\mu P_{\eta_2}\psi,$$ where $\epsilon_{\eta_1,\eta_2}=\pm1$, $g_c$ is a contact interaction coupling constant, $\Lambda$ is the


that the lower index carried by each of these fields labels its weak isospin value. Moreover, $\tilde{S}_{0\nu}$ and $\tilde{V}_{0\nu}$ are those LQ related to the introduction of right-handed neutrinos.

The scalar LQ interactions are then parametrized according to the Lagrangian density, $$\begin{array}{r c l}
{\cal L}_S&=&\lambda^L_{S_0}\overline{q^c_L}i\tau_2\ell_LS^\dagger_0\\
 &+&\lambda^R_{S_0}\overline{u^c_R}\mu_RS^\dagger_0+
    \lambda^{R\nu}_{S_0}\overline{d^c_R}\nu_RS^\dagger_0
 +\lambda^R_{\tilde{S}_0}\overline{d^c_R}\mu_R\tilde{S}^\dagger_0+
    \lambda^{R\nu}_{\tilde{S}_{0\nu}}\overline{u^c_R}\nu_R
            \tilde{S}^\dagger_{0\nu}\\
 &+&\lambda^L_{S_{1/2}}\overline{u_R}S^\dagger_{1/2}\ell_L+
    \lambda^R_{S_{1/2}}\overline{q_L}S^\dagger_{1/2}i\tau_2\mu_R
 +\lambda^L_{\tilde{S}_{1/2}}\overline{d_R}\tilde{S}^\dagger_{1/2}\ell_L+
    \lambda^R_{\tilde{S}_{1/2}}\overline{q_L}\tilde{S}^\dagger_{1/2}
            i\tau_2\nu_R\\
 &+&\lambda^L_{S_1}\overline{q^c_L}\vec{S}^\dagger_1\cdot
            i\tau_2\vec{\tau}\ell_L\
    +\ {\rm h.c.}
\end{array}$$ and similarly for vector LQ, $$\begin{array}{r c l}
{\cal L}_V&=&\lambda^L_{V_0}\overline{q_L}\gamma_\mu\ell_L{V^\mu_0}^\dagger\\
 &+&\lambda^R_{V_0}\overline{d_R}\gamma_\mu\mu_R{V^\mu_0}^\dagger+
    \lambda^{R\nu}_{V_0}\overline{u_R}\gamma_\mu\nu_R{V^\mu_0}^\dagger
 +\lambda^R_{\tilde{V}_0}\overline{u_R}\gamma_\mu\mu_R
      table. See (\[eq:Sen\]) for the definition of $\sigma({\cal O};h_X)$.[]{data-label="Table4"}

[^1]: On leave from the Institute of Nuclear Physics, Catholic University of Louvain, Louvain-la-Neuve, Belgium\
    E-mail: [govaerts@fynu.ucl.ac.be]{}

[^2]: On leave from the Instituto de Física, Universidad de Guanajuato, P.O. Box E-143, 37150 León, México\
    E-mail: [lucio@ifug3.ugto.mx]{}

[^3]: In heavier nuclei, the same axial electroweak probe enables to address the issue of hadronic coupling and mass renormalization in the nuclear medium.

[^4]: The principle of the experiment lies in the comparison between the muon disappearance rates, through the usual electron decay mode, for both positive and negative muons, only the latter being subject to nuclear capture. Since this experiment does not measure the neutron recoil energy distribution, it has no handle on the neutrino energy spectrum nor on


you could possibly want to eat and you could easily spend a lot of money here. If you are looking to avoid the supermarket this is the place to go. We went on a wet Monday morning so the place was relatively quiet but can get busy on weekends.

A short walk from the market is the Granville Island Brewery. The brewery has its beers on tap with many of them worth trying. If you want to try several beers on offer the brewery offer a sample tray which allows you to try up to 4 beers for about $12.

The best way to get to Granville Island is to take the False Creek Ferry that runs from Beach Avenue. Its may cost more than the bus but it isusers and hide its presence. Furthermore, Alureon has also been known to disable antivirus programs on the computers it invades, which makes its detection practically impossible. One thing that might give it away, though, are frequent BSoD crashes. These have shown to often accompany the presence of a Trojan of this type on a given PC.

But unfortunately, stealing your account passwords, online banking login credentials and various other financial data is not everything that Trojans like this are capable of. They are uniquely versatile in the purposes that they can be employed for. For example, malicious programs like this can easily be set to keep track of your keystrokes, tap your microphone and hack your webcam so as to spy on you and your environment. This can commonly


The Broad Institute is testing the limits of what ‘nonprofit’ means

hen a federal patent court ruled that the nonprofit Broad Institute of MIT and Harvard could legally license its version of the CRISPR-Cas9 genome-editing system, it opened the door to millions of dollars of revenue for the institute. It also contributed to the seismic shift occurring in science whereby tax-exempt research institutes established under an emerging model of “free market philanthropy” can amass money to further their research and protect their commercial interests.

The Broad Institute, a tax-exempt organization established by contributions totaling $1.4 billion by Eli Broad and Ted Stanley, is hardly the only one of these nonprofit models.

For instance, Napster cofounder and former Facebook president Sean Parker set up the nonprofit Parker Institute for Cancer Immunotherapy toearly shot at investing in Editas. That startup was founded by Feng Zhang, a core researcher at the Broad. Editas obtained an exclusive license to CRISPR-Cas9 from patent holders including the Broad for cash and stock equity, and began funneling $34.1 million (by the end of 2016) to reimburse the Broad’s legal fees in its court battle for the rights to CRISPR-Cas9. As millions were flowing from the now publicly traded Editas to the Broad, Editas cofounder David Liu was installed as a core member at the Broad, further strengthening ties between the Broad and its commercial partner. Zhang and colleagues then patented an application of a related genome-editing technique called CRISPR-Cpf1 and, through the Broad and other institutions, granted Editas an exclusive license to use this technology


for medical applications.

This kind of tight relationship with a for-profit corporation clearly puts the concept of “nonprofit” to the test. How many tens of millions should the Broad be allowed to take from Editas? How many of the founders of Editas should be installed into leadership positions at the Broad? Does granting of exclusive licenses constitute a special favor, a quid pro quo? Those are the kinds of questions that regulators should be asking, but aren’t.

The Broad, possibly aware that its nonprofit mission could be at risk, published at the end of 2016 a guide to its intellectual property licensing philosophy. It noted that “non-profit institutions [like the Broad] should, in general, favor non-exclusive licenses over exclusive licenses.” The document immediately walked back that principle, saying that investorsobjectives. I asked the Internal Revenue Service and the office of the Massachusetts Attorney General about this, but both declined to comment on how financially entangled the Broad and Editas could legally become and what, if any, breaches could trigger an investigation.

The privatization of federally funded science could scarcely have been imagined when national funding was first proposed. During World War II, President Franklin D. Roosevelt directed his chief of military research and development, Vannevar Bush, to create a model for funding science after the war. In Bush’s poetic 1945 document, “Science the Endless Frontier,” he argued for robust funding through the NIH and the creation of the National Science Foundation. These and other efforts led to a briskly expanding scientific research base in the US. In the


by globally renowned scientists from multiple academic institutions and prominent venture capital firms with a mission of translating the potential of CRISPR genome editing into medicines. While there will always be a few critics, most objective observers believe the bi-partisan Bayh-Dole Act has been a tremendous success. At Editas Medicine, we proudly partner with leading universities and research institutions in the U.S. and abroad, including Broad Institute, Massachusetts General Hospital, Harvard, MIT, Duke, Iowa, Wageningen University (Netherlands), and the University of Tokyo as we all attempt to help patients suffering from genetically defined or genetically treatable diseases.

Lee McGuire wrongly characterizes my article by suggesting that I believe Congress made a mistake in instituting the Bayh-Dole. My article is specific to the Broad’s abuse of power related to “surrogate table ::
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leads to a larger contribution to the confining potential in Eq. (\[energy\]). This result is consistent with that from QCD sum rules [@Suzuki:2015est; @Hilger], and from effective chiral models [@Sasaki:2014asa; @Suenaga2].

Constituent quark model calculation
===================================

Let us next perform a more detailed analysis using a non-relativistic constituent quark model. We start from the following nonrelativistic Hamiltonian. $$\begin{aligned}
H=\sum_{i=1}^{n}(m_{i}+\frac{\textbf{p}^2_i}{2m_i})-\frac{3}{4}\sum_{i<j}^{n}\frac{\lambda^c_i}{2}\frac{\lambda^c_j}{2}(V^{C}_{ij}+V^{SS}_{ij}),\end{aligned}$$ where $m_i$ and $\lambda^c_i/2$ are the quark masses and the color operators of the $i$’th quark, and $V^{C}_{ij}$ and $V^{SS}_{ij}$ are the confinement and the hyperfine potential between quark $i$ and $j$, respectively. We adopt the following form for the confinement and hyperfine potential [@Bhaduri:1981pn], $$\begin{aligned}
V^{C}_{ij}=-\frac{\kappa}{r_{ij}}+\frac{r_{ij}}{a_0}-D, \label{vc_ij-01}\end{aligned}$$ $$\begin{aligned}
V^{SS}_{ij}=\frac{\hbar^2c^2{\kappa}}{m_im_jc^4}\frac{1}{(r_{0ij})^2r_{ij}}e^{-(r_{ij}/r_{0ij})^2}
{\sigma}_i\cdot{\sigma}_j. \label{v-ss}\end{aligned}$$ Here, $r_{ij} = |\textbf{r}_i-\textbf{r}_j|$ is the distance between quark $i$ and $j$, and $(r_{0ij})$ is chosen to depend on the respective masses as follows: $$\begin{aligned}
r_{0ij}=1/(\alpha+\beta \frac{m_im_j}{m_i+m_j}).\end{aligned}$$too small quark masses as the non-relativistic approximation will become invalid. Fourth, the present argument will not be reliable for light-light meson systems as the hyperfine potential $V^{SS}$ in Eq. (\[v-ss\]) will become unrealistically large as the light quark masses decrease. $V^{SS}$ in fact will increase at a $1/m_q^2$ rate with a decreasing constituent quark mass, eventually leading to a negative pion mass, which does not seem to be realistic.

As a last point, let us discuss the results of the $D^*$ and $B^*$ mesons, shown as red triangles in Figs.\[D-meson\] and \[B-meson\]. It is seen in these figures that these mesons within our model behave almost exactly in the same way as their pseudoscalar counterparts. This means that our model predicts the $D^*$ and $B^*$ meson masses to increase


*Fusarium* spp., the production of fusaric acid was lower upon co-culture with a second fungus (data not shown). A ratio of around 0.5 (14 co-cultures) can be explained due to a dilution effect as two fungal metabolomes are present in the extract and might be interpreted as a non-affected production. Substantial lower ratios (0.1 and less) were observed for 36 co-cultures. This can be putatively explained by detoxification of fusaric acid \[[@B37-molecules-21-00370]\].

3. Experimental Section {#sec3-molecules-21-00370}
=======================

3.1. Taxon Sampling and Phylogenetic Analyses {#sec3dot1-molecules-21-00370}
---------------------------------------------

More than a hundred fungal pure cultures were obtained from nails fragments of patients suffering onychomycosis at the Centre Hospitalier Cantonal Vaudois (CHUV, Lausanne, Switzerland) \[[@B38-molecules-21-00370]\], from plants and soil. Pure cultures and co-cultures were prepared as previously described \[[@B19-molecules-21-00370]\] and growth conditions are detailed in the [Supplementaryco-culture. Although strain-specific, fusaric acid is overall produced, and in the highest amounts, by strains of the *F. oxysporum*--*F. fujikuroi* spp. complexes and not by strains of the *F. solani* spp. complex. However, the production of this mycoalexin can be strongly induced by interaction with a second fungal strain, this for strains that were not producing a significant amount of fusaric acid in pure culture.

The exact mechanism that triggers such a metabolic response remains to be studied in more depth to understand if specific conditions are needed for the upregulation of this mycotoxin. Recently, it was found that trace amounts of metal (Cu^2+^ and Zn^2+^) suppress fusaric acid production when the fungus (here *F. oxysporum* f. sp. *ciceri*) was cultured in liquid medium \[[@B59-molecules-21-00370]\]. Furthermore, a gene (FUBT)


fusaric acid production in the respective pure culture. Co‑cultures showing upregulation are shown in [Supplementary Figure S2](#app1-molecules-21-00370){ref-type="app"}. All strains are of human origin, except MYC860 and MYC906 (highlighted in red).](molecules-21-00370-g006){#molecules-21-00370-f006}

[^1]: These authors contributed equally to this work.

[^2]: Current Address: Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

[^3]: Current Address: Groupe Mer, Molécules, Santé-EA 2160, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Nantes, 9 rue Bias, BP 53508, F-44035 Nantes Cedex 01, France.
Creating your distribution model for China

an important component of a successful distribution strategy in China,

especially at the local level, where these networks may consist of only

a handful of decision makers.

Several distribution structures are available in China, including the

typical structures of distributorship, commission agency, franchise, trademark license and joint ventures. Apart from the usual business considerations such as whether the model can achieve better penetration into the market and serve the objectives of the brand owner, tax issues and actual logistic arrangements are also crucial in determining whether a certain structure is preferred. For example, it is common to use local agencies for importing cosmetic products due to certain testing procedures of the China Food and Drug Administration, and the distributors are supplied through such local agencies.

The most relevant


service lies outside a manufacturer’s core competencies. Few manufacturers have successfully transitioned from original equipment manufacturer to original designer and original brand owner.

With the liberalization of the commercial sector in 2004, a growing number of foreign agents and distributors have established themselves in China. A foreign company may establish its own entity or may enter into a joint ownership arrangement with a local company or importer. Through complex subcontracting networks, foreign distributors can work directly with traditional retailers. But these networks tend to lack advanced practices in demand planning, inventory management, and logistics networking—which leads to higher operational costs. This is primarily because such networking involves Chinese partners who lack a sophisticated knowledge of international-standard operations and technology.

Unless it is required by law that a joint venture beas $n!$, reflecting the uncertainty in the analytic form of the QCD coupling at low scales. Virtually all QCD processes are complicated by the presence of dynamical higher twist effects, including power-law suppressed contributions due to multi-parton correlations, intrinsic transverse momentum, and finite quark masses. Many of these effects are inherently nonperturbative in nature and require knowledge of hadron wavefunction themselves. The problem of interpreting perturbative QCD predictions is further compounded by theoretical ambiguities due to the apparent freedom in the choice of renormalization schemes, renormalization scales, and factorization procedures.

A central principle of renormalization theory is that predictions which relate physical observables to each other cannot depend on theoretical conventions. For example, one can use any renormalization scheme, such as the modified minimal subtraction scheme, and any choice


between observables. The renormalization group ensures that the forms of the CSR relations in perturbative QCD are independent of the choice of an intermediate renormalization scheme.

The Crewther relation was originally derived assuming that the theory is conformally invariant; [[*i.e.*]{}]{}, for zero $\beta$ function. In the physical case, where the QCD coupling runs, all non-conformal effects are resummed into the energy and momentum transfer scales of the effective couplings $\alpha_R$ and $\alpha_{g1}$. The general relation between these two effective charges for non-conformal theory thus takes the form of a geometric series $$1- \widehat \alpha_{g_1} =
\left[ 1+ \widehat \alpha_D( Q^*)\right]^{-1} \ .$$ We have dropped the small light-by-light scattering contributions. This is again a special advantage of relating observable to observable. The coefficients are independent of color and are theto be a step-function at the quark-mass thresholds. The figure shows clearly that there are hardly any plateaus at all for the continuous $\widetilde
{N}_{F,\overline{\mbox{\tiny MS}}}^{(0)}(Q)$ in between the quark masses. Thus there is really no scale below 1 TeV where $\widetilde
{N}_{F,\overline{\mbox{\tiny MS}}}^{(0)}(Q)$ can be approximated by a constant; for all $Q$ below 1 TeV there is always one quark with mass $m$ such that $m^2 \ll Q^2$ or $Q^2 \gg m^2$ is not true. We also note that if one would use any other scale than the BLM-scale for $\widetilde
{N}_{F,\overline{\mbox{\tiny MS}}}^{(0)}(Q)$, the result would be to increase the difference between the analytic $N_F$ and the standard procedure of using the step-function at the quark-mass thresholds.

Figure \[fig:adiff\] shows the relative difference between the two different solutions of the 1-loop renormalization


the non-singlet hadronic width of the Z-boson, including finite quark mass corrections from the running of the coupling[@bmr]. The results are compared with the standard treatment in the $\overline{\mbox{MS}}$ scheme where finite quark mass effects are calculated as higher twist corrections.

The finite quark mass effects which are of interest are in leading order given by the “double bubble" diagrams, which are shown in Fig. \[fig:doublebubble\], where the outer quark loop which couples to the weak current is considered massless and the inner quark loop is massive. These correction have been calculated in the $\overline{\mbox{MS}}$ scheme as expansions in $m_q^2/s$[@Hoang] and $s/m_Q^2$[@Chetyrkin] for light and heavy quarks, respectively, whereas they have been calculated numerically[@Soper_Surguladze]. In addition the $\alpha_{\mbox{\scriptsize{s}}}^3$ correction due to heavy quarks has been calculated as an expansion inscheme or scale dependence. Recently it has been shown[@BPT] how the commensurate scale relation between the radiative corrections to $\tau$-lepton decay and $R_{e^+e^-}(s)$ can be generalized and empirically tested for arbitrary $\tau$ mass and nearly arbitrarily functional dependence of the $\tau$ weak decay matrix element.

An essential feature of the (Q) scheme is the absence of any renormalization scale ambiguity, since $Q^2$ is, by definition, the square of the physical momentum transfer. The  scheme naturally takes into account quark mass thresholds, which is of particular phenomenological importance to QCD applications in the mass region close to threshold. As we have seen, commensurate scale relations provide an analytic extension of the conventional [$\overline{\mbox{MS}}$]{} scheme in which many of the advantages of the  scheme are inherited by the  scheme, but only minimal


analytic V-scheme without any scale ambiguity. The commensurate scale relations provides the relation between the physical scales of two effective charges where they pass through a common flavor threshold. We also note the utility of the  effective charge in supersymmetric and grand unified theories, particularly since the unification of couplings and masses would be expected to occur in terms of physical quantities rather than parameters defined by theoretical convention.

As an example, the finite quark mass corrections connected with the running of the coupling for the non-singlet hadronic width of the Z-boson have been calculated in the analytic V-scheme and compared with the standard treatment in the $\overline{\mbox{MS}}$ scheme. The analytic treatment in the V-scheme gives a simple and straightforward way of incorporating these effects for any observable. Thison High Energy Physics, eds. Z. Ajduk and A. K. Wroblewski, World Scientific, p.705; J. Bartels, A. De Roeck and H. Lotter, Phys. Lett. [**B389**]{}, 742 (1996).

S. J. Brodsky, J. R. Pelaez, and N. Toumbas, hep-ph/9810424, to be published in Phys. Rev. D.

[^1]: Work partially supported by the Department of Energy, contract DE–AC03–76SF00515.


how much "lean" is invested. The rest seems to be window dressing on the different postures, which all correlate right back to Yang Luchans small frame. Not to say it isn't "necessary" window dressing or important, it's just not the "main" difference in my opinion.In Wu style, I have learned a 108 posture Saber form. Also a 108 posture Tai Chi Sword (I have heard it called a Gim, but don't know if I'm spelling that right) form. I learned the "fourth" generational forms of those, as my instructor was a fourth generation Wu member. I have seen demonstrated a "demo" or Olympic form of Wu style that is relatively new, but have not studied it in any depth.

That is just the one other family I have anycan provide it to you. The way it was explained to me, they have re-incorporated "cannon fist" back into their Taiji. I don't know that for sure, but some knowledgable people have told me that. Let me know if you're interested.

Wushuer, thanks for the information about the Wu Family forms. I think your account could also stand for the variety that exists in the other branches of Taijiquan.

By the way, “gim” (pronounced with the “hard ‘g’” of the English word “go” and with a mid-level tone) is one way to spell the Cantonese equivalent of the Mandarin word “jian.” Both mean “sword.” As you may know, many Taiji lineages have portions that go through Hong Kong or Guangdong (Canton), where Cantonese is the dominant language. Cantonese is not


their style. These shortened forms were apparently created to reach more people as they are easier to learn and perform. I'm going to go back there and look for the names of the movements. CQAha! Here they are:1 Opening (Qi Shi)2 Wave Hands like Clouds, only one (Yun Shou)3 Single Whip (Dan Bian)4 Punch under the Elbow (Zhou Di Chui)5 White Crane Spreads its Wings (Bai He Liang Chi)6 Brush Knee and Push (Lou Xi Ao Bu)7 Hands Strum the Lute (Shou Hui Pi Pa)8 High Pat on Horse (Gao Tan Ma)9 Thrust Palm (Chuan Zhang)10 Turn Body and Chop with fist (Zhuan Sheng Pie Sheng Chui)11 Step Forward, Parry, Block and Punch (Jin Bu Ban Lan Chui)12 Step Forward Grasp the Bird¡¯s Tail (Shang Bu LAN Quethat I can find in my entire state! Believe me, I've looked. Hard.I took the course with an admitted bias against "Yang style", as, let's go ahead and say it, most "Yang style" teachers in this country (USA, I guess I should add) wouldn't know their Tantien from their behind if you gave them a map and don't teach anything approaching a legitmate form of Taijiquan. There's a lot of what we called "new-age crystal wavers" out there CLAIMING to be teaching Taijiquan, but aren't.So I took that class and was extremely impressed by the level of skill of the instructors at my local YCF Center. I now find I really enjoy that 13 posture form. I do it at least once a day. Usually more. It is


tiny bits of it. I took it over ten years ago, and never got what you would call "proficient" at it. I am afraid I took it too soon after the Saber form and my brain only seems to want to remember the Saber. I remember all the warm ups and the version of the Nine Cuts that was associated with the Gim, slightly different from the Saber, but that's as far as I can recall.I'm afraid I don't remember much of my spear/staff form either. Too long ago and no viable way to practice it. Again, I remember the warm ups, I remember a lot of static postures, but I cannot remember the transitions to go between them. Let that be a warning to one and all!under the direct guidance of a Disciple or Master at all times, so despite the fact that I taught at that level for a number of years, I would not feel comfortable teaching others what I feel I have not yet Mastered myself.

Could I do this and be succesful?Sure. I know enough Taiji prinicpals to pull it off more conviningly than most and, after all, there's not a "Taijiquan Police Force" that goes around arresting fakes.The difference is, I couldn't mislead people like that in good conscience.Of course, what I would teach might be closer to the real thing, but that still wouldn't make it right.

Do you have any idea how hard it is to walk in to a classroom and the instructor has no idea what the


B or C and C' are severed.
If, however, the remaining portion of a coupler segment on either end of the terminal after the severing operation is too long, the remaining portion may in use come into contact with another member, thereby short-circuiting the terminal. Also, the insulation of the lead wire can be damaged if the remaining portion of the coupler segment at the rear (lead wire end) of the terminal is too long. On the other hand, if, for instance, the coupler segment at the front end of the terminal is cut off too short, damage to the contact portion of the terminal may occur.4.0 Working With My Login

My Login is a collection of sensitive information, such as your username and password. You can define a login so that two different applications can share the same login data.

Through the My Login page, you can view and edit Novell SecureLogin user data, such as usernames and passwords, that allow you to successfully log in to an application.

To use Novell® SecureLogin to automatically log you in to an application, you create a Login (set of credentials) and link it to that application.

If you add an application that has a predefined application, you need to link the login to it. You can provide login variables the next time that you access the application. However, you do not need to add or create login for applications


you doing?" "Hey!" "What are you doing?" "!" "What the hell are you doing?" "!" "No, you have to go through the sternum." "The sternum." " Like in the movies." " I know, I know." " One..." " What are you doing?" "!" "Two..." "Wait!" "Don't mind me, brother." "I'm just gonna take one of your clubs." "Hurley said it'd be all right." "Hurley, huh?" "Must mean you're off to save the day." "So..." "I can take one of these?" "Take the 5-iron." "I never use it." "That way, when you die in the jungle doing whatever you're doing," "I don't have to go looking for it." "Thanks, mate." "You know, you might want to square your shoulders a bit more." " You play golf?" " I'm scottish.""Cheers." "What the hell?" "Hey, come on." "Hey, move." "Let's move." "Hey, come on, come on, come on!" " What are you doing?" " Come on." "Come on," "Let's move it, let's move it." "What's your problem?" "Did you just kill that bunny?" "You know what a pacemaker is?" "What?" "They stick 'em in the tickers of people who've had bypass work, whose hearts need just a little jump, a kick start." "The rabbit had a small pacemaker set to deliver its kick start, should it get too excited... or anxious or frightened... or should it try to escape." "Assuming that you were telling the truth about your age and weight, your resting heart rate should be about 70 beats per minute." "Your active heart rate, however, that


place you've always wanted, George?"" "Sorry?" "What, don't you read?" "It's from "of mice and men."" "You'd like it." "Puppies get killed." "You bring me up here to kill me?" "Make that thing you put inside me blow up my damn heart?" "Your heart's not gonna blow up, James." "The only thing we put inside you was doubt." "Oh, the watch is a heart rate monitor, but nothing more." "Look." "We gave him a sedative, not a pacemaker." "How do I know that's the same bunny?" "That you didn't just paint an "8" on another one?" "You don't." "You son of a bitch." "The rabbit wasn't the thing I wanted to show you." "What the..." "You ever been to Alcatraz?" "Take the tour?" "Right now you're standing onCrab avocado tostadas

Use a corn
tortilla as a base then top with storecupboard crabmeat, guacamole-style Mexican dip and salad

Production-Takes 10 mins

Ingredients

1 small red onion, sliced into thin rings

juice 2 limes, plus wedges to serve

juice 2 limes, plus wedges to serve

170g can white crabmeat in brine, drained

2 spring onions, finely sliced

1 red chilli, deseeded and chopped

1 really ripe avocado, peeled, stoned and chopped

1 small garlic clove, crushed

2 corn tortillas

handful mixed salad leaves

Method

1-Put
the onion in a bowl and cover with half the lime juice and a good pinch each of
sugar and salt. Leave to soften while you get everything else ready.

2-Mix
together the crabmeat, spring onions and half the chilli. Season with black
pepper and set aside. Mash the avocado with the remaining lime juice,
garlic and some seasoning. You can leave it quite


this problem. And after a few months of pondering, I decided that my next exam would be based on a maximum score of 137. And on this exam, they didn’t do quite as well percentage-wise, but the average score was well into the 90s—and they were thrilled. This is behavior that no economist would think is remotely sensible.

TANYA OTT: So basically, you were getting at the idea that humans aren’t perfectly rational. You describe Homo Economicus versus Homo Sapien. What do you mean by those two terms?

RICHARD THALER: Homo Economicus—I call them Econs for short—they’re people you study in any basic economics class. They’re really smart. They can make any kind of calculation. Never forget anything. Unemotional. No self-control problems. And they’re complete jerks. If you leave yourthey bought a bottle of wine for $20 and it was now worth $75, and they could sell it for $75. What would it feel like when they went to drank one of these bottles? And we made it multiple-choice.

TANYA OTT: Option #1: $0—I already spent the money. Option #2: $20—that’s what I paid for it. Option #3: $75—that’s what economists would say would be the right answer, because that’s what you could get for it.

RICHARD THALER: And my favorite, the mental accountant’s answer: I saved $55 by drinking this bottle, because it’s worth $75 and I only paid $20.

TANYA OTT: So back to the bar patrons. This time, a four-top: two sisters and their husbands.

SHERRY KRELL: I’m Sherry Krell, and I’m from Birmingham. I am a Hebrew


on top of the trashcan that is a very simple visual of how you should put your trashcan out. The tops of the trashcans have embossed arrows that show which direction they’re supposed to be in, but it’s very easy to miss that information when you’re actually rolling out your cart.

MARIEL BEASLEY:Right, so these are very bright stickers that will go right on top of the can, with three illustrations for how to put your can out. Some of them will get the sticker. Some of them will also get a letter from their trash collector that basically says, “Hi, My name’s Sam. I’m your garbage man. And it will make my job a lot easier if you do this right. Here are three steps to do thissaw the old language the New Mexico’s Department of Workforce Solutions had been using for a while, and other people saw new messages.

JOY FOREHAND: To us it became: Let’s provide messaging where it has the biggest impact, where it can really affect somebody’s decision and nudge them, sway them into providing really robust information and correct information.

TANYA OTT: Can you give me an example of a switch in wording? Is there something that stands out where it was worded this way and then you changed it and worded it that way and then got completely different results?

MIKE GREENE: The one that’s really my favorite: You file your initial claim and figure out, “Okay, I’m eligible to get paid.” Then what happens is you have to come back every


accurately report their earnings” message were twice as likely to go back and report new earnings. New Mexico continues to test messages and refine the way it interacts with people filing for unemployment.

And that’s what research is about, right? Figuring out how and where something is effective, and when it’s not, why not? To close out this podcast, let’s hear from some big minds and rising stars in behavioral economics about what most occupies their thoughts these days.

MICHAEL NORTON: We had this intuition . . .

TANYA OTT: That’s Michael Norton.

MICHAEL NORTON: I’m Michael Norton. I’m a professor at Harvard Business School and a psychologist by training who actually became interested in behavioral economics because I was studying social interactions and happiness, and it turns out that we needtravelled with bears or cats, but it resolved itself in favour of the cats.

The word köttr, used in the other two mentions of Freyja’s cats, could also mean a martin or weasel. Just to make it more confusing. Unlike bears, you can actualy see this one, since they’re all about the same size, and if cats were mainly feral or only semi-domesticated, it’s easy to see how the word became a catch-all term for agile medium-sized animals with fur.

Bears may be larger and more fitting animals for a Nordic deity, but the cat seemed more appropriate for a goddess who combined the Venusian and the witchy. At any rate, modern commentators on Norse myth seem to have settled that they’re cats, at least until proved otherwise.1

Did Thor give


Vassal and tributary states of the Ottoman Empire

Vassal States were a number of tributary or vassal states, usually on the periphery of the Ottoman Empire under suzerainty of the Porte, over which direct control was not established, for various reasons.

Functions
Some of these states served as buffer states between the Ottomans and Christianity in Europe or Shi’ism in Asia. Their number varied over time but notable were the Khanate of Crimea, Wallachia, Moldavia, Transylvania and the Principality of Serbia from 1815 until its full independence half of century later. Other states such as Bulgaria, the Eastern Hungarian Kingdom, the Serbian Despotate and the Kingdom of Bosnia were vassals before being absorbed entirely or partially into the Empire. Still others had commercial value such as Imeretia, Mingrelia, Chios, the Duchyto star in his wrestling/horror movies which were then the rage of Mexican cinema. Mil Máscaras was the first Lucha Libre personality that was created specifically to be a movie star, since his whole persona and flashy look was designed initially for the movies. (His real life wrestling career followed and grew out of the excitement generated by his film appearances.)

Vergara's two regular movie stars had suddenly become unavailable. Santo had walked out on him over a contract dispute, and Blue Demon was injured unexpectedly and would require a prolonged time-out. Not wanting to stop making his successful cinematic quickies, Vergara decided to transform Lucha Libre newcomer Mil Máscaras as the star of his next two movies. Mil began a movie career that has continued to this day,


six-man tag team match.

In April 2012, Máscaras was inducted into the WWE Hall of Fame by his nephew Alberto Del Rio.

Personal life
Máscaras has never been unmasked in the ring, and like most masked luchadores, he goes to great lengths to conceal his true appearance and personal life. Máscaras has two brothers who wrestled, Dos Caras and Sicodélico. He has two sons and two daughters with his first wife, who died in 1975, and two daughters with his second wife, whom he married in 1995. His nephews are Alberto Del Rio (also known as Dos Caras Jr., El Hijo de Dos Caras, and Alberto El Patrón); the current El Hijo de Dos Caras; Sicodélico Jr.; and Hijo Del Sicodelico.

Máscaras is an avid golfer and plays in many charity golfus shake our heads in disbelief that parents could be so horrible to their children and that the system could, in turn, be so horrible in its response. And then we forget about it until the next report comes along.

This year, despite a general pull back on finances, the state has actually funded more social worker positions. Too bad those social workers will find the same dismal support systems in place as their predecessors. You see, without the wrap around support services many troubled families need, helping a family to heal and become whole is nothing more than a pipe dream.

Social workers are trained to do a lot of things. Those who go into front line work intervening with troubled families, removing kids from dangerous situations and placing


diagnosis is implemented in order to avoid a failure, increasing the availability and reliability of the traction system. The solution proposed provides both the FDI and severity of the fault. An easy to tune solution is proposed in the face of input filter parameter variations and fault magnitude to be detected. Thus, the proposed solution is simple to adapt to other railway traction drive configurations.

The paper has the following structure: [Section 2](#sec2-sensors-18-01998){ref-type="sec"} presents the railway traction drive description and problem statement. [Section 3](#sec3-sensors-18-01998){ref-type="sec"} proposes a SMO for DC-link voltage and catenary current sensors. [Section 4](#sec4-sensors-18-01998){ref-type="sec"} proposes a fault diagnosis and reconstruction approach for DC-link voltage and catenary current sensors. In [Section 5](#sec5-sensors-18-01998){ref-type="sec"}, the validation in a HIL platform is presented. Finally, the discussion and conclusions are given.

2. RailwayFrozen has reportedly signed a contract worth $200,000 a year

According to internal information published by Turkish League of Legends website 5mid.com, the 1907 Fenerbahce Midlaner Frozen has signed a contract worth $200,000 a year.

This would make him the highest-paid player in the Turkish league.

Due to Frozen’s incredible performances in the Turkish league, Fenerbahce (please don’t sue us for not using the “1907” all the time, thanks) was able to 3-0 BAUSuperMassive in the Turkish Champions League finals and qualify for Worlds.

From then on, the team was able to dominate the Play-In-Stage, taking the first place of Group D against Honk Kong Attitude and Rampage.

Fenerbahce was then placed in Group C, where they didn’t win a single game against the likes of Samsung Galaxy, RNG and G2 Esports.

Frozen will


possibility of upper mantle serpentinization by seawater penetration at the Marie Byrd Seamount province. Hints of seaward-dipping reflectors indicate some degree of volcanism in the area after break-up. A set of gravity anomaly data indicate several phases of fully developed and failed rift systems, including a possible branch of the West Antarctic Rift System in the Amundsen Sea Embayment.establish Bloomington held over after the termination of the written the lease. Because Bloomington held over, the written lease is deemed to have renewed for the year. Thus, Bloomington controlled the park and is liable for Kuruzovich's injuries.[3]
*412 Bloomington argues there could have been no extension of the lease, even one arising out of its own actions in holding over, because it was prevented from assenting to a lease extension without the approval of the Bloomington Parks Board. In making this argument, Bloomington relies on I.C. XX-XX-X-XX, which reads, in relevant part:
"(a) Real and personal property may be granted, devised, leased, bequeathed, or conveyed to a city for park purposes ...
(b) The city may take and hold the property in trust or upon conditions that are approved by


the [park] board. The property and the rents, issues, and profits from it are subject to the exclusive control of the board."
We find this statute did not prevent Bloomington from renewing the lease by holding over. The statute does not state that the Parks Board approval is a precondition to a city taking or renewing any interest in land. Rather, the statute states that if a city seeks to take an interest in land, the Parks Board is charged with the duty to establish the conditions under which the city will take the interest. In this case, when the Bloomington Parks Board negotiated and approved the written lease, it determined the conditions under which Bloomington should take an interest in Sherwood Oaks Park. In holding over, Bloomington merelyand the ultimate result." Havert v. Caldwell (1983), Ind., 452 N.E.2d 154, 159.
Here, Bloomington's design and maintenance failure resulted in a softball field being placed too near an obscured, raised manhole cover. The relationship between the field and the cover raised the reasonably foreseeable possibility  perhaps even probability  that someone would trip, fall, and be injured. When Kevin Coates threw the ball he may have given rise to a condition which allowed the accident to occur, but he did not proximately cause the accident. Bloomington, then, cannot avail itself of immunity under I.C. 34-4-16.5-3(9).
Bloomington also claims immunity under I.C. 34-4-16.5-3(11), which provides immunity for failure to inspect property other than the property of a governmental unit. This argument fails for two reasons. Kuruzovich did not seek


covered in other instructions, and if the substantial rights of the tendering parties would be prejudiced by failure to give the instruction. Captain & Co. v. Stenberg (1987), Ind. App., 505 N.E.2d 88; Board of County Commissioners of the County of St. Joseph v. Arick (1985), Ind. App., 477 N.E.2d 112. Obviously, the court cannot give instructions which do not correctly state the law. Furthermore, the court is not required to give an instruction which covers matter already covered in other instructions. Thornton v. Pender (1978), 268 Ind. 540, 377 N.E.2d 613; Captain & Co., supra.
Bloomington challenges the trial court's refusal to give its tendered instruction number 2. This instruction was a restatement of the terms of the Recreational User Statute. We have held that the Recreational Userthe failure to exercise that care is negligence."
If Bloomington intended this instruction as an instruction on the defense of open and obvious defect, the trial court certainly did not err in refusing to give it, since open and obvious defect is a defense to products liability actions and not to negligence actions. Bridgewater v. Economy Engineering Co. (1985), Ind., 486 N.E.2d 484. If it was intended as a contributory negligence instruction, the trial court still did not err in refusing it, since the trial court instructed the jury on contributory negligence. Bloomington was not entitled to an instruction on an issue which the trial court had already given an adequate instruction. Captain & Co., supra.
Bloomington next challenges the court's refusal to give its tendered instruction number 8, which


dealt with the burden of proof and preponderance of evidence. Bloomington concedes the trial court covered the preponderance of the evidence in another final instruction, but claims the court failed to give the burden of proof instruction in the preliminary instructions as mandated by Ind.Rules of Procedure, Trial Rule 51(A). The trial court stated on the record it had given a burden of proof instruction. Bloomington, as appellant, bore the obligation of demonstrating error occurred, Cox v. State (1985), Ind., 475 N.E.2d 664, yet Bloomington did not choose to supply this court with the record of the preliminary instructions. We will not presume the trial court failed to give an instruction which it said it had given and, consequently, we find no error here.
Bloomington submitted, and the trialof reasonable care under all the circumstances in the maintenance and design of parks. See McKenna, supra; Mills, supra. No Indiana case has ever applied the traditional economic benefit distinction between invitee and licensees to those injured in public parks. The trial court was correct not to do so here.
Furthermore, Bloomington was not entitled to have instruction 10 read. The trial court read Kuruzovich's tendered instruction 2, which stated:
"The City of Bloomington has a duty to exercise reasonable care in the design, construction, maintenance and repairs of its parks for the safety of persons rightfully frequenting the parks and equipment. In designing, constructing, maintaining and repairing parks, the City of Bloomington must exercise that care which would be exercised by an ordinary prudent person under the circumstances."
This instruction


defendant. Lambert v. Parrish (1984), Ind. App., 467 N.E.2d 791, vacated on other grounds, Lambert v. Parrish (1986), Ind., 492 N.E.2d 289. Bloomington simply has not met its burden. It failed to order up those parts of the record containing evidence on how the field and manhole appeared at the time of the accident. Since Bloomington failed to provide this court with any evidence relevant to the conditions at the time of the accident, we cannot be so presumptuous as to hold, as a matter of law, that Kuruzovich was contributorily negligent for failure to use care around a known hazard.
Finally, Bloomington argues the evidence that Kuruzovich's injuries were caused by accident was insufficient. Bloomington's expert witness testified that it was highly improbable, but not impossible, for theof 1791 and 100296.
100296
Calculate the smallest common multiple of 1200 and 20.
1200
What is the lowest common multiple of 2387 and 768180?
8449980
Calculate the smallest common multiple of 71155 and 99617.
498085
Find the common denominator of 107/822 and -62/5.
4110
Find the common denominator of 38/107297 and 107/246.
643782
Find the common denominator of -19/660 and -91/16434.
164340
What is the common denominator of -101/31932 and 1/108?
95796
What is the least common multiple of 63 and 2387?
21483
What is the common denominator of 63/1240 and -49/122100?
7570200
What is the common denominator of 91/3286 and -49/155290?
4813990
What is the common denominator of -79/2489289 and -25/1357794?
14935734
Find the common denominator of 131/13870 and -23/11.
152570
What is the least common multiple of 3822 and 43316?
129948
Find the common denominator of -145/924 and 71/27720.
27720
What is the smallest common multiple of 425160 and 12?
425160
Calculate the common denominator of 71/2


-127/12?
2146920
Find the common denominator of -81/3296 and 29/20.
16480
What is the common denominator of 5/297 and -17/264?
2376
Calculate the smallest common multiple of 260 and 293137.
5862740
Calculate the lowest common multiple of 162260 and 2440.
324520
What is the common denominator of -39/44 and 11/337364?
3711004
Find the common denominator of 11/45352 and 23/136056.
136056
What is the least common multiple of 25665 and 295?
25665
Calculate the lowest common multiple of 50 and 10455.
104550
What is the least common multiple of 1506 and 14376?
3608376
Calculate the least common multiple of 10 and 77552.
387760
Calculate the smallest common multiple of 2619 and 293328.
293328
Calculate the lowest common multiple of 879408 and 788.
879408
Find the common denominator of -27/8 and 79/259466.
1037864
Calculate the common denominator of -37/987 and 17/9870.
9870
Calculate the common denominator of -5/609 and -53/9918.
69426
Calculate the least common multiple of 850100 and 22.
9351100
Calculate the leastcommon multiple of 21 and 1589.
4767
Calculate the lowest common multiple of 6465 and 12.
25860
Calculate the least common multiple of 60 and 22188.
110940
What is the smallest common multiple of 12 and 312896?
938688
Calculate the common denominator of -139/719274 and -107/7512.
2877096
What is the common deno


fact that I was a sleepwalker was particularly odd until I went to college. I have five siblings, and all of us were sleepwalkers and/or sleep-talkers as kids. Three of us (that I know of) have continued this behavior into adulthood, which I guess is unusual. We often share our funnier stories of sleepwalking at parties and family gatherings, because…well…they’re kind of weird stories, and after a few drinks they can be downright hilarious.

The sleepwalking story I share is one from college. I was dreaming that I was trapped in some kind of a large box. I couldn’t find my way out, so I thought of my friend, Bob, who was really smart. I knew he could figure out how to rescue me from the box. When Ihave happened because I never brought him into bed with me…for this very reason!)

I also almost injured my poor, snoring husband several times as I dove across him to catch our imaginary baby as he fell off the side of the bed. Sometimes my sleepwalking brought me into the hallway where I dreamed that our boy was just about to fall down the stairs. Always my dream was of me searching for him or rescuing him from impending doom. Even in sleep, my mind just could not rest.

So I’d like to take this opportunity to give props to Mother Nature for the brain chemical/hormone cocktail she invented for the purpose of mother/baby bonding. Seriously, that is some powerful stuff. You are handed this rashy, stinky, screaming baby that


waking me up going shh shh shh while he dreamed about trying to calm a baby, and more than once I woke myself up jerking awake thinking one of the girls had rolled off of my chest. Lordy. Here’s hoping you get some good solid rest soon, even if it’s a long shot, it’s a nice idea, isn’t it? You’re spot on about the love part and Mother Nature.

Lol! You have twins, right? It must have felt strange to NOT be holding at least one – it’s not surprising that you guys were dreaming of holding and calming them! Luckily, I’m writing these posts a few years after my son’s baby years, so I’m finally getting some rest…hooray! Hope you are too!!

I think every roommate I’ve had hasHot Tamale Festival, Oct. 13-16. “If everything goes as planned we would love, absolutely love, to be open for the tamale fest. …But if not, we’re going to be open as fast as we can,” he said, noting they will have a soft opening at first to make sure the staff is well trained and the food is excellent.“We don’t want to rush ourselves, we want to make sure everything is covered.”A local family businessHarmon said Hot Tamale Heaven began about 35 years ago, when his father and mother, Willie and Inez Harmon, decided to delve into the tamale business.“I was just a young lad of 6- or 7-years-old. My father started this business, my mother and father. My father at the time was working a factory job


liked the product. And he began to slowly grow it from that point on,” Harmon said, laughing as he noted he and his five siblings were his father’s first laborers.“We began to help him in business when we got home for school, and on more than one occasional he would get us out of school if he had a big order for tamales and needed some help,” he said.But, the tamales were too good to just sell to neighbors. Harmon said they started selling tamales on Washington Avenue and what is now Stein Mart Square. He said often his mother would be set up at Stein Mart Square and his father at the old Greenville Mall location.“And it took off from there. My brothers and sisters and Ifound in three patients on intraoperative ultrasound. A total of 27 patients with 50 liver lesions were treated successfully with laparoscopic RFA. The mean maximum tumor diameter was 5.5 +/- 2.0 cm. The mean length of time for RFA per lesion was 20.7 +/- 11.9 min, and the mean blood loss was 134.4 +/- 88.9 ml. Laparoscopic cholecystectomy was performed simultaneously for gallstones in 13 patients and for abutting of gallbladder from hemangioma in 2 patients. In addition, 3 patients also had a laparoscopic deroofing of simple hepatic cysts. Although postoperative low-grade fever and transient elevation of serum transaminase levels were observed in 13 patients, there were no complications related to laparoscopic RFA. During a median follow-up period of 21 months (range, 12-42 months), complete lesion necrosis was


We want to keep the entire community together through this journey.

As a producer, this has been the most exciting time for me, creating an experience that is built to grow. We will get to go on this journey with you, looking for opportunities to continually surprise the community with the unexpected. This is truly a living Battlefield.

Experience the Tides of War with your Company on Xbox One, PlayStation® 4, and PC – starting on October 11 for the EA Access and Origin Access Play First Trial*, October 16 for Battlefield™ VDeluxe Edition early enlister access, and October 19 for the Battlefield™ V Standard Edition. Pre-order here to secure your copy of Battlefield V.for 1 h at room temperature and incubated with primary antibody overnight at 4°C, then washed with 1xTBS-T and incubated with the appropriate horseradish peroxidise conjugated secondary antibodies for 1 h at room temperature. The enhanced chemiluminescence (ECL) (GE health care) system was used to detect bands, which were imaged with a Chemi-Doc MP system (Bio-Rad). Densitometry was performed using the ImageLab software version 4.0 (BioRad). Protein levels were normalised to β-tubulin, α-actinin or to total protein levels on the PVDF membrane after the transfer. Quantified results represent n = 3 samples. Statistical significance determined using Student's t-test (P \< 0.05).

Results
=======

The effect of hypoxia on Dicer protein levels in breast cancer cell lines
-------------------------------------------------------------------------

Hypoxic regulation of Dicer gene expression was initially measured at the protein level. Dicer protein levels in two different breast cancer cell


this time point, no significant changes were observed in mature or precursor miRNA levels in MCF7 cells exposed to hypoxia (0.1% O~2~) vs. normoxia after 16 h (data not shown).

In a similar experiment undertaken with a longer duration of hypoxic exposure (0.1% O~2~ for 48 h) several miRNAs were significantly up or down regulated in MCF7 cells (see Additional file [1](#S1){ref-type="supplementary-material"}: Figure S1). Eight miRNAs were significantly up regulated (see Additional file [1](#S1){ref-type="supplementary-material"}: Table S2), and four miRNAs were significantly down regulated in hypoxia when compared to normoxia (see Additional file [1](#S1){ref-type="supplementary-material"}: Table S3). Even following a longer duration of hypoxic exposure (0.1% O~2~ for 48 h) there were no significant changes between individual precursor miRNA: mature miRNA ratios either with hypoxia (see Additional file [1](#S1){ref-type="supplementary-material"}: Figure S2) or, surprisingly, followingnormoxia. **B**, Pre-miR-21 and miR-21 expression, precursor/mature ratio in MCF7 cells exposed to hypoxia (0.1% O~2~ for 48 h) vs. normoxia**. C**, Pre-miR-185 and miR-185 expression, precursor/mature ratio in MCF7 cells exposed to hypoxia (0.1% O~2~ for 48 h) vs. normoxia. Data represent normalized mean ± S.E (error bars) (n = 3). miRNA levels were analysed by RT-PCR and normalised to RNU6B levels.](1471-2407-14-533-10){#F10}

The effect of hypoxia on microRNA function
------------------------------------------

Given the multiple potential influences of hypoxia on miRNA biogenesis proteins and RISC activity, the effects of hypoxia on miRNA function were studied. For this a plasmid containing the 3'UTR of ZEB1 gene downstream of a Renilla luciferase (RL) reporter was used \[[@B37]\] along with a plasmid that expresses a pre-miR-200b. ZEB1 is an E-cadherin transcriptional repressor involved in epithelial


hypoxia on the expression of genes encoding proteins that are essential in miRNA biogenesis. This is consistent with previous work indicating co-ordinate regulation of the levels of these proteins. When Dicer expression was suppressed there was a significant decrease in TARBP2 levels in keeping with previous reports \[[@B43]\]. Similarly, when TARBP2 levels were reduced by siRNA treatment there was a modest decrease in Dicer protein. When Dicer and TARBP2 levels were examined over a time course of hypoxic exposure both proteins seemed to decrease co-ordinately. Previously others have shown a powerful influence of the levels of Dicer protein on the levels of TARBP2 and vice versa \[[@B11],[@B43]\] and post transcriptional cross regulation between Drosha and DGCR8 \[[@B51]\]. In this work we have also observed a further relationship linkingbiogenesis.

Whilst hypoxia exerted only modest effects on the production of mature miRNAs, we did see a significant influence of hypoxia on the operation of an exogenously introduced precursor miRNA. The processing and function of miR-200b was reduced in hypoxia when compared to normoxia. Dicer and TARBP2 proteins are involved in the processing of a precursor miRNA in to a mature miRNA and the reduction of both these proteins in hypoxia would likely have impacted on the maturation of the pre-miR-200b.

This work points towards the operation of non-HIF but HIF hydroxylase dependent pathways by which hypoxia controls reductions in gene expression. This effect of hypoxia appears to operate via several mechanisms of regulation and we have shown important influences of the HIF hydroxylase PHD2 and of the hypoxically regulated


these abuses.

Most important, the Ethiopian government should ensure that no one is ever arrested for exercising their basic rights, including by peacefully expressing their political opinions.

That means urgently overhauling Ethiopia’s draconian civil society and counter-terrorism laws. But change is unlikely to happen unless key regional actors such as the African Union, the African Commission on Human Rights Peoples’ Rights, and Ethiopia’s foreign donors make their concerns known.

Turning a blind eye to the abuses in the centre of Addis Ababa should no longer be an option.

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Advocacy4Oromia (2010-2020)

Advocacy for Oromia was established in 2010 with the purpose of enabling and empowering Oromo people by providing accurate and timely information that will help to make better choices to create the kind of future in which they wish to live.
It also[R proteins as a reflection of disorders in the cellular reception mechanisms in kidney diseases].
As many as 47 patients with amyloidosis and 31 with chronic glomerulonephritis (CGN) were examined for the blood serum content of R proteins, chemotactic activity of blood leukocytes and the degree of the inhibitory influence of the autologous serum on chemotaxis. Amyloidosis and CGN were marked by an increase of the level of receptor proteins. A reverse correlation was established between the rise of the content of R proteins and the chemotactic properties of leukocytes. In CGN, the rate of demonstration of the high titers of R proteins and the magnitude of the chemotaxis decline depended on the disease phase (the degree of activity) whereas in amyloidosis, these reactions differed insignificantly in patients with


set of game
rules, and wherein the mating game cards have indicia representing the
plurality of stable positions of the collectible game pieces and game
play values of the collectible game piece,b. casting the collectible game
pieces onto a flat playing surface such that the game pieces come to rest
in any one of the plurality of stable orientations, thereby obtaining a
game play value for a roll,c. referencing the mating game cards to
determine the play value of the roll,d. determining whether a victory
condition has been satisfied and if yes, then the game is ended, and if
not, play continues by repeating the casting the collectible game pieces
step and the referencing mating game cards step until a victory condition
has been satisfied.

24. A rollable game piece comprising a random outcome generator having a
visual aspect that isuse of dice with a unique random outcome generator that
takes the form and function of a toy figurine with multiple stable
orientations, wherein the figurines when combined with a playing surface
designed for the game, allows two or more people to engage in a novel
method of play and game of chance and strategy.

SUMMARY OF THE INVENTION

[0006]In accordance with this invention, there is provided a game of
chance including a plurality of collectible game pieces, a game mat, a
plurality of collectible cards and associated rules. The game pieces are
in the form of the novel collectible game piece, a random outcome
generator, of this invention. Players take turns by casting the game
pieces onto the playing surface, preferably the game mat.

[0007]In accordance with this invention, there is also provided an
improved random outcome generator for games


and places
the cards onto the flat playing surface and the at least one opposing
player selects a predetermined number of cards from his hand and places
the cards onto the flat playing surface; Step 5 of performing a challenge
round wherein the active player and the at least one opposing player
casts one or more game pieces onto the flat playing surface and play
select cards of choice; Step 6 of performing a resolution round wherein
the active player and the at least one opposing player will determine the
results; Step 7 of determining whether a victory condition has been
satisfied and if yes, then the game is ended, and if not play continues
to the next step; Step 8 (Where a victory condition has not been
satisfied) of performing a player status change wherein one of theat
least one opposing player becomes the active player; and Step 9 of
repeating steps 3-7 until a player has achieved victory conditions.

[0009]The method, game of chance and collectible game pieces of this
invention may be applied to any type of theme or genre including, but not
limited to, historical, comic book, science fiction, mythical, political,
sports, entertainment, martial arts, war or battle related themes or
genres. The advantages of the present invention will be understood more
readily after a consideration of the drawings and the detailed
description.

[0010]It is an object of this invention to provide a unique random outcome
generator that takes the form and function of a toy figurine and
collectible game piece with multiple stable orientations.

[0011]It is a further object of the present invention to provide a novel
method of play that incorporates games of chance,


goal of
highest score wins.

[0046]Miniature figurines ("miniatures") are used in many games to enhance
the gaming experience and in many cases they are the central game
component for game play. Some miniatures are integrated with a complex
record-keeping system to track game statistics. The collectible game
pieces 2, 50 described herein are three-dimensional character figurines
representative of, but not limited to, an animal (e.g., see FIG. 3), a
human (e.g., see FIG. 1), a humanoid type character, a fictitious
character, a mythical character, a comic book character, a science
fiction character, a martial arts character, a political character, a
historical based character, a machine or robot, any anthropomorphic
character, an entertainment celebrity or sports figure.

[0047]The collectible game pieces 2 are designed with different but
distinctive sizes, stances, extremities, touch points, stable
orientations, and all with the same elasticity designed about adirectly affects the stability of the collectible game piece
2 when cast on a flat surface. The more stable a collectible game piece 2
stable orientation, the greater the probability of achieving that stable
orientation when cast on a flat surface. The designs are formed to result
in unpredictable behavior resulting in a probability based outcome when
collectible game pieces 2 are cast upon a flat playing surface. In order
for the three-dimensional collectible game piece 2 figurine to roll, the
size, stance and material are taken into consideration.

[0049]The polyhedron shape is used as a model for designing collectible
game pieces 2 in the form of miniature figurines. A polyhedron is a
geometric shape with flat surfaces. The collectible game piece 2 of the
present invention, on the other hand, is created to resemble a character
figurine. To create


piece depicted in FIG. 3. In the embodiment depicted, the polyhedron
comprises eight sides, forming intersections 110, 112, 114, 116, 118,
120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140. Each plane of the
polyhedron is defined by the points along its intersection with the
adjacent planes such that one plane is defined by the intersection points
along 128, 132, 134, 136 and another plane is defined by intersecting
points along 122, 126, 128, 130 and so on with each of the faces of the
imaginary polyhedron. The touch points of the collectible game piece 50
fall within and/or define its respective plane.

[0052]Unlike dice, rolling a three-dimensional character will not result
in even probabilities for each random outcome (except in the case where
it has been designed to do so). The dynamics of rolling an objectappendage may also be manipulated to create
a more stable landing surface, or stable orientation, on a particular
portion of the figurine.

[0055]The probability may also be manipulated by adding accessories to the
collectible game piece 2, 50 character. FIG. 6 depicts an embodiment of a
collectible game piece having supplemental weights. These accessories may
be weapons (as more fully described below) or may take the form of clip
on or snap in weights. Referring to FIG. 6, the body of the collectible
game piece 50 may be formed to receive a supplemental weight 142, 146 via
a recess 144, 148 where it may be removably snapped in during game play.
The supplemental weight 142, 146 may take a generic shape such as a
ball-like object, a disk shaped object (as depicted in FIG. 6), a
geometric shaped object, a


for example a (nine by nine) or (ten by ten) but not limited
to that. A grid matrix is basically a series of intersecting vertical and
horizontal axes. The grid will be divided into any number of squares as a
result of the intersections.

[0098]Novel Method of Game Play

[0099]Various embodiments of the present game invention comprise game
components (collectible game pieces 2, 50) that can be cast onto a
playing surface and methods of play suitable for one or more players. In
some embodiments, the object of the game is to acquire the highest number
of points. The players may compete against one another to establish or
maintain the highest score at the end of a set of game turns. Each of the
players may play with one or more collectible game pieces 2, 50, selected
by each playerfrom a collection of collectible game pieces 2, 50. Each
player may have her or his own collection of collectible game pieces 2,
50 acquired by purchase, competition or trading of the collectible game
pieces 2, 50.

[0100]Different rule sets can be provided. In some preferred embodiments,
a single rule set is used for any given tournament or game. In one
embodiment of the present invention, a game with collectible game
components (e.g., collectible game piece 2, 50 figurines, cards and game
mat) are provided. In one aspect, the present game invention will be
played in the context of imaginary battles or fights between characters
in an imaginary world. In one embodiment, players can represent a
character in the game.

[0101]In one method of play, each player takes his/her turn throwing, or
casting, the collectible game pieces 2, 50 in his


2, 50 which are cast onto a playing
surface.

[0102]During game play, players may take turns casting collectible game
pieces 2, 50 onto a playing surface. The playing surface can be a game
mat, tabletop or other planer surface, including playing surfaces
designed for use with the present invention. "Casting" the collectible
game pieces 2, 50 means throwing, tossing, rolling, dropping or bouncing
the collectible game pieces 2, 50 onto the playing surface. After each
player's turn, players can determine the value of each roll. In some
embodiments of the present invention, the stable collectible game piece
2, 50 orientation or "pose", the physical location of the game piece 2,
50 on the game mat and card interaction can affect the value of the turn.
In some embodiments, collectible game piece 2, 50 characters can be
associated with special abilities. Theseactive player
may now place required number of cards onto the table from their hand. At
the stage of the ready round various cards and combination of cards will
be brought into play and placed face-up on the table top. Examples of
cards to play but not limited to these cards include character cards,
event cards, location cards, equipment cards, effect cards, interrupt
cards, action cards, reward cards, grid cards and the like. Some cards
may affect one or all players in the game. In some embodiments of the
game rules, cards in the game will have a card cost to bring them into
play. Card cost is the number of cards you must discard from your deck to
play the card. When the active player has completed card placement, the
opposing player may now play his or her


does score the victory points
for the removed character, but the active player still gets to play any
`come into play` effects on the new character.

[0146]3) The active player can simply put the newly flipped character into
the character discard pile. This triggers nothing and no victory points
are awarded.

[0147]If at any time the character deck runs out of characters, the
character discard pile is simply reshuffled and becomes the new character
deck.

[0148]The above detailed descriptions of embodiments of the invention are
not intended to be exhaustive or to limit the invention to the precise
form disclosed above. While specific embodiments of, and examples for,
the invention are described above for illustrative purposes, various
equivalent modifications are possible within the scope of the invention,
as those skilled in the relevant art will recognize. For example, while
the game is describedembrace it. Live in it.

When I walked back into the room that day, I chose not to share what I had just experienced. And I think that was a mistake. Over the last year this group has become a significant source of encouragement for me. Many of them have become dear friends. I should have trusted them then but the truth is, I didn’t want their pity.

But if I had it to do all over again, I’m thinking I should have stayed in my seat, and when it came to my turn (tears and all) simply said, “I’m Amy and I’ve never been pregnant. And I’m beginning to understand that maybe it’s a gift.”

God’s healing of our hearts began to happen long before we became parents. And it


for 12 years and a mom for 6 years would have molded, shaped, changed, broken, and strengthened me. I never imagined having the confidence that this woman has to fight for her people and (on her bravest days) pursue her dreams.

And I never knew the courage and sacrifice it would take to slow down and lean in to the children God has graciously placed in my care. To choose the unexpected because it provides safety and security for my oldest.

To choose less productivity because it gives affection to my youngest.

To choose being their mom first over the pursuit of the many desires and passions and professional pursuits.

To choose to see my children fully in the brokenness of their stories but not wholly without the hope of their futures.

Beingthan a stroller to me.

When we were waiting to adopt our first child, our caseworkers had been very intentional about encouraging us to wait to prepare for our baby. Don’t decorate a room…don’t buy all the clothes…don’t have a baby shower…just wait. Everything you need, they explained, you can get when you bring your baby home.

I had watched people close to us walk through the heartbreak of situations falling through. And when a decorated and fully stocked room remained empty, I knew that there was wisdom is not fully preparing. In the end, there is nothing certain about the adoption process, and nothing is a done deal until the judge says it is.

I needed some physical representation of God’s provision. I needed something to hold on to. So


packed it away in the closet. But otherwise, I enjoyed looking at it when I walked past the room. I cried over it when situations fell through. I found myself staring at it when life was overwhelmingly hard. When darkness threatened to swallow me up, this was the physical manifestation of ultimate hope.

And just like the usually-not-so-nice cat that God used to comfort me in the midst of our infertility, this stroller, this tool, this inanimate object, became sacred. After having looked at the stroller for more than a year, when I put Jamie in the bassinet that first night (and checked on him roughly 135 times), it felt as though it was more than a bed. I was wrapping my baby in the longings of my heart.day and night.

This might be one of my favorite spots in Central Park. And those two little people are for sure the best.

It was a year ago this weekend that Brandon and I visited New York City for the first time. It may come as a surprise that neither of us had been here before, and here we found ourselves not only here, but we were actually exploring whether we could LIVE here. Only a few people knew the reason for our trip, so under the cover of “celebrating our anniversary” a little bit early, we came.

On the plane 1 year ago.

At Riverside Park a few months ago.

These two pictures were taken before our first visit (on the airplane) and after we’d been here a few months later.

And


made them in the mud yesterday, remember?" "So we could walk in them when they dried." "How clear it is." "Clear as the top of the world." "It is the top of the world." "Of course." "We came from way down there." "Tiptoe on top of the world." "Listen." "Do you hear it?" "Is it music?" "Music, sir," "I heard it today and I brought it with me so you could hear it, too." "I knew you'd like it." "And I have a gift for you." "It's why I brought you here." "Would you be good enough to look?" "Oh, Peter, how beautiful." "How did you do it?" "I built it for you out of the clouds, the heavens and the stars." "All very simple." "All very beautiful." Enter-PSSession -Session $dc1
  Invoke-Command -ScriptBlock {C:\TPAdmin\Greenshot-INSTALLER-1.2.10.6-RELEASE.exe /VERYSILENT /LOG="C:\SOFTWAREINSTALL.LOG"
 Remove-Pssession $dc1

A:

Enter-PSSession is for interactive use only, so not suitable for use in a function.[1]
Instead of using Enter-PSSession, pass the session you've created with New-Session to the Invoke-Command command's -Session parameter, which will run the command in the context of that (remote) session.
# Define your function...
function Invoke-InstallerRemotely {
  param([string] $ComputerName)
  $session = New-PSSession -ComputerName $ComputerName
  Copy-Item C:\TPAdmin\Greenshot-INSTALLER-1.2.10.6-RELEASE.exe -Destination C:\TPAdmin -ToSession $session
  # Do NOT use Enter-PSSession.
  # Pass your session to Invoke-Command with -Session
  Invoke-Command -Session $session -ScriptBlock {C:\TPAdmin\Greenshot-INSTALLER-1.2.10.6-RELEASE.exe /VERYSILENT /LOG="C:\SOFTWAREINSTALL.LOG"
  Remove-PSSession $session
}

# ... then invoke it.
# Note that functions must be defined *before* they're called.
Invoke-InstallerRemotely -ComputerName DC1

[1] Using it in a function means that an interactive session on


Q:

Undefined local variable or method for module

I have module CurrencyExchange with following methods
 CURRENCIES = %w(uah rub eur usd)

 def available_currencies
   CURRENCIES.join(' ').downcase.split.permutation(2)
 end

and when i want to use available_currencies with
define_method
 available_currencies.each do |(c1, c2)|
    define_method(:"#{c1}_to_#{c2}") do |cr| ... end end

i have got an error
undefined local variable or method `available_currencies'
 for CurrencyExchange:Module (NameError)

but when i use it like
     CURRENCIES.join(' ').downcase.split.permutation(2).each do |(c1, c2)|
  define_method(:"#{c1}_to_#{c2}") .... end end

it works fine
Why it happens?

A:

I think you need to write def self.available_currencies

stimulated the expression of Max without affecting c-Myc. Quantitation with real-time quantitative PCR detected on the ABI Prism 7700 Sequence Detection System revealed that adrenomedullin and calcitonin gene-related peptide (CGRP), as well as serum, up-regulated Max mRNA levels and that down-regulation of Max mRNA after serum deprivation was prevented by adrenomedullin. Neither adrenomedullin nor CGRP affected c-Myc expression. Transfection of a Max-expressing plasmid into endothelial cells rescued the apoptosis induced by serum deprivation. Neutralization with anti-adrenomedullin antiserum or blockade with a CGRP receptor antagonist, CGRP(8-37), reduced Max mRNA levels in growing endothelial cells and enhanced apoptosis after serum starvation. Introduction of an antisense oligodeoxynucleotide against Max mRNA using transferrin receptor-operated transfer led to inhibition of both adrenomedullin-induced up-regulation of Max transcripts and its cell survival effect, whereas random,


var left = Math.floor(Math.random()*850);
  var top = Math.floor(Math.random()*850);
  this.shapeElement = $(shapeHtml);
  this.shapeElement.css({
    'margin-left': left,
    'margin-top': top,
    'width': widthAndHeight,
    'height': widthAndHeight,
  });
  $("body").append(this.shapeElement);
}

Shape.prototype.colour = function() {
  var colours = '0123456789ABCDEF'.split('');
  var randomColour = "#";
  for (i = 0; i < 6; i++) {
    randomColour+=colours[Math.floor(Math.random()*16)];
  };
  this.shapeElement.css({backgroundColor: randomColour});
}

$(document).ready(function() {
var square = new Shape();
square.draw();
square.colour();
});

<!DOCTYPE html>

    <meta charset="UTF-8">
    <title>Shape</title>

 {
            result[i] = arr[i];
        }
    }
    return result;
}

This is an assignment in my java class and we have not learned Lists (one of the answers I stumbled upon in my googling) yet so that is not an option for me.
As it is now, it should be outputting:
[this, is, example, of, call]
Currently it is outputting: [this, is, null, example, of]
Any and all help will be much appreciated!

A:

You need 2 indices in the second loop, since you are iterating over two arrays (the input array and the output array) having different lengths.
Besides, newLength is a confusing name, since it doesn't contain the new length.