then an abrupt transition would be evident within overlap area 104 and image compositing software would have a difficult time properly stitching the images together. Conventionally, images are aligned to form a larger composite image after all of the smaller images have been captured, typically by software on a computer separate from the imager used to capture the smaller images. If adjacent smaller images cannot be sufficiently aligned (e.g., because the as-captured smaller images were vastly askew or do not share a sufficient overlap area), the resulting composite image may be unsatisfactory. Therefore, a method and system enabling a user to better align small images used to form a composite image is desirable.miserly spell from George O’Brien (2/14) that dismissed both Xavier Marshall (4) and Steven Taylor (0). Fray ran out Monank Patel for 3 and the US were struggling at 39/3 off 7.4 overs. They recovered somewhat with knocks from Jaskaran Malhotra (33) and Aaron Jones (40), but when Jones fell to a stunning leaping catch by Rawlins on the boundary, they were 100/5 needing 42 off the last 4 overs. This was reduced to 18 off 2 before some excellent death bowling from both man-of-the match Rawlins and Leverock meant the US only scored 11 off the last two overs and saw Bermuda home by six runs for an upset win.

The second game of the day pitted T20I debutants Cayman Islands against Canada, who batted first. The highlight


Rodrigo Thomas set out quickly in an effort to beat the rain, reaching 39/0. But Mother Nature had the last laugh when the heavens opened at the end of the fourth over. The game was abandoned just six balls before an official result could be declared. It was tough on Canada who were well ahead on DLS, but the points were shared.

In the afternoon game, rain again played a major part. It all started routinely enough with the USA skittling the Cayman Islands for 89, but the Americans’ chase was to cause more than a few puzzled looks.

They were creeping along at such a snail’s pace that they fell behind the DLS target at the five over mark that would have constituted an official result had it beensuccessive fifty and a second successive man-of-the-match award.

The afternoon game was the big one, a game on which the fate of the tournament was to hang. With Canada on 7 points, Bermuda 5 and the USA just 2, a Bermuda win would see both the hosts and Canada heading to the Emirates website to book their flights to Dubai.

Fray struck first blood for Bermuda, winning the toss and inserting the Americans. In the second over, Monank Patel lobbed a simple catch to Delray Rawlins off the bowling of Malachi Jones – the only remaining member of Bermuda’s 2007 World Cup team and the bowler of the ball that resulted in that Dwayne Leverock catch! Sluggo’s nephew Kamau helped Bermuda get their second wicket in the next over here


Q:

WebRTC renegotiation between Chrome and Firefox

I am able to establish WebRTC connection between Firefox and Chrome, but renegotiation between Firefox-Chrome does not work properly.
There is no problem in renegotiation between Chrome-Chrome pair and Firefox-Firefox pair.
With Firefox-Chrome pair, when I start the renegotiation from chrome after removing or adding a track, renegotiation is successful and onremovestream or onaddstream callbacks are triggered on firefox correctly.
But when I start the renegotiation from Firefox after removing or adding a track using pc.removeTrack or pc.addTrack,  renegotiation was successful without any error. But in Chrome onremovestream or onaddstream callbacks are not triggered. When I get the MediaStream using pc.getRemoteStreams I can see that tracks' ids are changed after renegotiation, but MediaStream does not work when I tried to play it.
One oddRConv08

2008 US Republican National Convention Market

This graph is also available in flash format with the datapoints annotated, or in a simple jpg format.

Graph in Flash format (this image may take a few seconds to load)

Graph in JPG format (use this link if you are unable to see the graph above)


the ARL4DΔ16C transfected cells exhibit an abnormal, swollen morphology. Bar, 10 µm. (C) Quantification of the ARL4D mutant protein present in the mitochondria. The data represent the results of three independent experiments. At least 100 cells from each population were examined. The data represent the mean ± SD. \* p\<0.005 vs ARL4D(T35N) transfected cells.](pone.0043552.g004){#pone-0043552-g004}

ARL4D(T35N) Dissipates the Mitochondrial Membrane Potential through its C-terminus {#s2d}
----------------------------------------------------------------------------------

To study the significance of the ARL4D(T35N) association with mitochondria, mitochondrial function was examined. We first used MitoTracker Red CMXRos, a mitochondrial membrane potential (ΔΨ~m~)-sensitive fluorescent mitochondrial dye, to monitor the ΔΨ~m~ in cells expressing ARL4D mutant proteins. MitoTracker Red CMXRos accumulates only in actively respiring mitochondria that have an intact ΔΨ~m~ [@pone.0043552-Pendergrass1]. As shown in [Figure 5A](#pone-0043552-g005){ref-type="fig"}, cells that overexpressed ARL4D(WT) or ARL4D(Q80L) showed normalprecise temporal and spatial control of their GTP binding and hydrolysis. The conformational differences that accompany the binding of GDP or GTP can directly account for the changes in their affinities for specific proteins, lipids, and membranes [@pone.0043552-DSouzaSchorey1], [@pone.0043552-Moss1]. By expressing two ARL4D Thr-to-Asn mutants, T35N and T52N, we found that inactive forms of ARL4D localize to the mitochondria. Thr35 is a conserved residue in the phosphate-binding P-loop, mutation of which has been used to investigate the inactive, presumably GDP-bound, form of small GTP-binding proteins. However, a study by Macia et al. showed that mutation of this conserved Thr residue in ARF6 results in a mutant defective in guanine nucleotide binding with low affinities for GTP and GDP (Macia et al., 2004). These reserachers subsequently cloned a new


from GE Healthcare (Little Chalfont, Buckinghamshire, United Kingdom), and the Alexa Fluor 594 or 488-conjugated anti-rabbit and anti-mouse antibodies were obtained from Invitrogen.

Expression Plasmids {#s4b}
-------------------

The cDNAs corresponding to ARL4D, ARL4C, ARL4A and their various mutants were cloned into the mammalian expression vector pSG5 (Stratagene, La Jolla, CA, USA), as previously described. These constructs were used to express untagged ARL4s [@pone.0043552-Li1]. To express C-terminally myc-tagged ARL4D(T35N), the ARL4D(T35N) fragments were cloned into pcDNA 3.1/myc-His A (Invitrogen). To express N-terminal His-tagged ARL4D(T35N) and (T52N), ARL4D(T35N) and ARL4D(T52N) fragments were cloned into pET32a (Novagen). The plasmid expressing Bax-GFP was kindly provided by Dr. Pei-Hsin Huang (National Taiwan University).

Cell Culture and Transfection {#s4c}
-----------------------------

COS-7 cells and HeLa cells were obtained from the American Type Culture Collection (ATCC) (Manassas, VA). Human rhabdomyosarcoma (RD) (ATCCthe mitochondria-enriched fractions were treated with 0.1 M Na~2~CO~3~ (pH 12), 0.1% or 1% Triton X-100, or isotonic mitochondrial buffer (Mock) for 1 h on ice and centrifuged at 20,000×*g* for 20 min. The resulting pellet and supernatant fractions were analyzed.

The submitochondrial fractionation with digitonin was performed as previously described, with minor modifications [@pone.0043552-Sharer1]. The mitochondrial preparations (above) were incubated with increasing concentrations of digitonin (Sigma) in the isotonic buffer at the protein concentrations described in the figure legends. The preparations were incubated on ice for 30 min with occasional mixing by inversion. The preparations were then quickly diluted with 3 volumes of mitochondrial isotonic buffer and centrifuged at 20,000×*g* for 20 min at 4°C. The supernatant was saved separately. The pellet suspensions were assayed by Western blotting


for 30 min at 37°C, washed twice with prewarmed medium to remove excess dye, and then fixed in prewarmed growth medium containing 4% formaldehyde for 15 min at 37°C. The quantification of MitoTracker fluorescence was performed using Axiovision 4.6 software (Carl Zeiss). The images were taken under the same conditions, and any intensity-saturated images were excluded from the analysis. The area around each cell was delineated, and the fluorescence intensity was measured in pixels. The background fluorescence was obtained from a cell-free field in each image and subtracted from the actual fluorescence. The cationic dye JC-1 emits a bright red fluorescence after forming aggregates in intact mitochondria. Mitochondrial aggregates do not form when the ΔΨ~m~ is disrupted; rather, the dye remains in monomeric form in the cytoplasm andthat they are both fused to the skull and jaw bones by thin ridges (ankylodont) as well as placed in deep sockets (thecodont). They are also serrated, similar to those of archosauriforms but unlike practically every other archosauromorph. Although not all of the teeth are preserved in good condition, those that are have a curved shape and are compressed from the side, making them knife-like, similar to most carnivorous archosauromorphs.

Spine and ribs

Vertebrae

The Tasmaniosaurus holotype preserves 2 presacral (pre-hip) vertebrae, one probably from near the transition between the neck and back and the other probably from mid-way down the back. The cervico-dorsal (neck-back) vertebra is slightly compressed with a shallow depression each side, and does not possess an opening for the spinal cord. Both the neural arch (the


Hearing and hearing loss in 5-year-old children. Pure-tone thresholds and the effect of acute otitis media.
Air and bone conduction pure-tone thresholds of 420 unselected urban children were measured with standard clinical audiometry. The mean of air conduction pure-tone averages (average threshold at 0.5, 1 and 2 kHz) was 8.6 dB HL in girls and 8.3 dB HL in boys. In only 5 ears (0.6%), was this average greater than or equal to 35 dB HL. The threshold greater than or equal to 35 dB HL at 4 kHz was found in 1.4% of the ears and at 8 kHz in 4.1%. The bone conduction threshold greater than 20 dB HL at any of the frequencies from 0.5 to 4 kHz was very rare, and only once, at 4internet doesn’t need government watchdogs, ready to pounce whenever someone’s feelings get hurt. Again, the idealism behind the bill is nice, but there’s just no way it can be implemented without a lot of people getting falsely accused in the process. But, hey, that doesn’t matter, right? This is Arizona we’re talking about!

Arizona: Come for the hate, stay because our views on the world haven’t changed in over a century.


Focal segmental glomerulosclerosis and kidney transplantation.
The recurrence rate of focal segmental glomerulosclerosis after kidney transplantation is ranging between 20% and 40%. Focal segmental glomerulosclerosis is associated with poor graft survival. In this review, the etiology, pathogenesis, clinicopathological features, risk factors of recurrence, and updated lines of management are discussed.L Hernandez/HOU/ECT@ECT
cc:
Subject: Re: Bay State

Good Elizabeth,
Could you give me an update on this matter.  Please let me know if you need
anything from me or if you want me to speak to someone.

Thank you
isabel
---------------------- Forwarded by Isabel Y Resendez/HOU/ECT on 09/11/2000
10:29 AM ---------------------------

	Enron North America Corp.

	From:  Shawna Johnson @ ENRON                           09/05/2000 11:32 AM

To: Isabel Y Resendez/HOU/ECT@ECT
cc:
Subject: Re: Bay State

I have forwarded the following request to Elizabeth Hernandez.  She handles
the East desk.  Any deals regarding the Central, Ontario or West desk please
send to me!!

:  )
smj

Isabel


the metal is corroded with a residual oxidizing agentxe2x80x9d. By this anticorroding treatment, it is possible to prevent the electrochemical corrosion of the metal wirings to a considerable extent. The term xe2x80x9celectrochemical corrosionxe2x80x9d refers to the corrosion of the metal accompanied by the battery action of the formed closed circuit which includes the metal, the pn junction, the metal and the polishing liquid component on the pattern of the wafer. The method further comprises the steps of immersing the anticorroded major face of the wafer or keeping it in a wet state so that it may not become dry. The term xe2x80x9cwet stockxe2x80x9d generally means xe2x80x9ckeeping or transferxe2x80x9d while preventing a dry state by immersing the wafer in pure water or the like, by feeding a pure watershower or by keeping the wafer in a saturated vapor atmosphere. The method then provides the step of post-cleaning the major face of the wafer which has been kept in the wet state. The xe2x80x9cpost-cleaningxe2x80x9d treatment is generally performed before the surface becomes dry, with a view to clearing the wafer surface of undesired particles, such as abrasive grains introduced at the polishing time. This cleaning treatment frequently involves both a mechanical cleaning treatment, such as a scrub cleaning treatment using a brush, and a weak etching treatment with a chemical solution.
A summary of the features of the invention will be briefly described as follows.
1. A process for manufacturing a semiconductor integrated circuit device, comprising the steps of:
(a) forming a metal layer whose main component is a metal,


provide summaries of the summaries.

Rep Gowdy does not want the FBI determining for him what is relevant and what is not, noting that he may interpret the content of one 302 differently than Mr. Herring does. Gowdy also takes exception to being told that Congress will need to file a FOIA request in order to be given access to the missing 302s.

He asks, “Since when did Congress have to go through FOIA to obtain 302s from an investigation that’s not even resulting in any prosecutions, that your boss has already said is over, since when did we have to go through FOIA?”

The stumbling and fumbling for words of Mr. Herring makes it clear that he’s covering up for the wrong, politically motivated decisions of Comey and his accomplices,has allowed him to retire. With Solo Capital under his belt and the success of the company doing so well, he has been able to really focus his avenues of interest on Autism Rocks. Solo Capital UK has multiple offices located in Central London and Dubai where they continue to provide successful, safe business transactions. Solo Capital employs some of the most efficient, reliable management team that is highly experienced and professional in their field of work. They strive to provide exceptional services to each and every client.


My Communities

My Discussions

My Email Digests

Announcements

Morning FMily....MiMi in NC....and the rain has arrived....woke up too darn early this am and then it seemed like forever until I was able to go back to sleep....about the time I got to sleep....the furbabies decided it was time for them to get up and go out....so I left them out of their room and tried to let them out the door....they refused....it was raining and raining hard. They hate to get wet to begin with. I knew they needed to go but that was NOT going to happen. So they settled back down and waited until it stopped raining. Finally they were able to get outside and by this time Harley arrived for the week-end. My older son dropped her off asall... So nice to be typing... this has been a worse then worse month... Still waiting to battle the high enzymes in my liver... No sclerosis... no fatty liver... but they did find a stone like from my kidney in it... and it twisted my liver... So that might be the cause... Don't know if it is or what happens from here until Tuesday when I go see my favorite dr...

My diabetes isn't doing a lot better but is crashing more then having highs so my hopes are up... the Dr I see on the 6th of June will be working with it and hopefully taking care of my cyst on my thyroid... I am anticipating that worrisome... for I have had cancer 7 times but I also


nicer still to have them ' home' before we leave.

DH and I took in the new Star Trek movie Into Darkness in 3D yesterday afternoon. DH also paid more for the larger theater, larger, reclying, seats and of course the bigger screen. Floor to ceilling and the surround sound was amazing. Good movie, not so much a girl's one tho. DH liked it and the actors who play Kirk and Spock are dead on to the orginals. It's more than worth the price of addmission. Of course the first Spock made a camio and that was a nice touch.

Not a lot of plans for my day. Gonna stay here pretty much. No errands to do. No appointments. That really says my next week as well. But I likeonto the next post. Sending gentle hugs and well wishes to all. Have a great weekend everybody. LindaR.

Back from mom and dad's ...Went over earlier today..and dad had messed up his pills..was doing ok...got the pills sorted out (hopefully correctly)..and then had a talk about the need to look into assisted living..or what our options are..I do think they would do better with more people around..I think they get so bored there...just nobody around most of the time..but the cost is so outrageous..So back to figuring out who will take them..

After the pills got a chance to work..dad didn't seem to be to bad..so I took mom and we walked around Costco..She wanted to buy something..but really wasn't much for her to buy...I got the eggs I wanted


we walked around Costco..She wanted to buy something..but really wasn't much for her to buy...I got the eggs I wanted and I took her home...She doesn't last all that long either..

Related Drug Reviews

Report Problems With Your Medications to the FDA

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

The opinions expressed in WebMD Communities are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. Communities are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions mayladies, and so was only open to under 40s. In 1953, former members of Bournemouth Ladies Circle formed their own group, Tangent.

In the 1990s, Ladies Circle opened up  membership to non wives/female partners of Tablers/ ex Tablers

Like the three other clubs in the movement, there are various Tangent clubs in towns and cities across the UK, and overseas.

Recently, some Tangent clubs have opened their doors to non ex Circlers.

Tangent clubs are affiliated to the National Association of Tangent Clubs (NATC). The members of each club will usually meet monthly, and organise various social events, and also activities to raise funds for charity or to support the community. Clubs will often hold Friendship or Fellowship evenings and invite other clubs in the neighbourhood to attend. Members of different


or a comma (Done this, using another list and list comprehension)
Check if there are any commas next to each other and then delete duplicates. (I should be able to do this rather easily)
Use a "for" loop to check the positions in the list, and when finding a comma, merge all items in the list prior to this comma, and up until the previous comma, together. (This is what I cannot do)

Any responses would be highly appreciated.

A:

You can split the list on the ',' character, then iterate over each sublist and join the characters that are digits.
>>> s = "1231,fdkgjdkfj45,294d"
>>> [''.join(i for i in chunk if i.isdigit()) for chunk in s.split(',')]
['1231', '45', '294']

If you are not yet familiar with list comprehensions (which is what is shown above) here isthis done and sent it to some local tile laying companies for quotes. The responses I have received have indicated that this is not the way they would recommend prepare a floor for laying tile and they recommend alternatives. After I received those responses I went to a tile store and asked about this and they also said not to do this.
I have three questions

Is the way described in the book a good way to prepare floor for
laying tile?
Why would he write this in his book if it wasn't a
    good/standard way of preparing the subfloor?
If you were having a
    tile floor installed in your house what subfloor preparation would
    you want assuming you are looking for the highest


bacgkround and then you attach another mouseout event. That's bad.
You are attaching click event "live" and mouse* with normal procedure. Why? Basically if you need live attaching use it, otherwise better stay clear (better performance).
It is much easier to use css classes to change UI. Like

CSS
.menu_clickable { background-color: #FFF; /* default color */ }
.clicked { background-color: #FCC; /* color for clicked button */ }
.mouseover { background-color: #F00; /* color when hovered */ }

HTML

first

second

third

jQuery
$(document).ready(function () {
    $(".menu_clickable")
        .mouseover(function () {
            var t = $(this);
            if (!t.hasClass("clicked")) { data centers to work harder and burn more electricity in the process.

Security and privacy weaknesses abound in IoT networks but wireless connectivity is a notorious hacker’s hangout. About 90 percent of all IT networks will have an IoT-based security breach within two years.

Put bluntly, if we keep doing what we are doing now, much of the IoT we are all anxiously awaiting is going to suck.

“We live in a real world where bandwidth is neither infinite nor free. There’s a lot of data being generated. We talk about 50 billion sensors by 2020. If you look today at all the sensors that are out there, they’re generating 2 exabytes of data. It’s too much data to send to the cloud. There’s not enough bandwidth, and it costs too


    int spanStart = in.getSpanStart(span); // If you;ve found one

                if (lastImageSpanPosition == spanStart)
                    continue; // check if image is first span (avoid creation of empty spans).
                res.add(new SpannableStringBuilder(in.subSequence(lastImageSpanPosition, spanStart))); // add all previous spans as a single Spannable object

                ImageSpan imageSpan = (ImageSpan) span;
               far as Hungary. The good thing about them is that they are bilingual; they have learned several foreign languages and can thus liaise very effortlessly from clients.The next time you find yourself looking for the best escorts from Europe, then consider trying Baltic escorts; you can never go wrong with them.

Conclusion;

The next time you find yourself looking for the best escorts from Europe, then consider trying Baltic escorts; you can never go wrong with them

Most people go on holidays to relax and get away from the daily hectic lives they lead. A holiday with family in a serene destination is the ideal idea for most people. However for others, a holiday entails more than just relaxing in a quiet hotel. Sex tourism has become increasingly popular with many


that the country is gearing itself to host the FIFA World Cup.

Conclusion;

The above 5 destinations are among the top sex tourism hotspots. There are many more including Spain, Colombia, Kenya, even Indonesia.

Sin city is the Disneyland fantasy location for grownups – where anything can take place – where anything goes and where other halves will certainly never ever figure out.

Its mischievous, raunchy advertising motto, ‘What happens in Vegas, stays in Vegas’, represents the wicked side of tourist. It has to do with sex and also sin, not credibility, green meadows and also terrific mountain sights.

Vegas is a destination that provides the opposite of ethical usage, caring for the world and worrying about environment change. It has to do with conspicuous consumption and luxury instead of neighborhoods and alsoa "conscious coma" and intubated. The other six victims suffered minor injuries. None of their names has been released.

Witnesses said that the truck, which had been modified for off-road use, seemed to accelerate as it approached the intersection. "He revved the throttle like crazy. We heard the RPMs build," Alex Bissett, a student at Hemet, told the Riverside Press-Enterprise. "I'm still trying to wrap my head around it. I've seen a lot of crazy stuff, but this tops it."


*
 * THIS SOFTWARE IS PROVIDED BY ERIC YOUNG ``AS IS'' AND
 * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
 * IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
 * ARE DISCLAIMED.  IN NO EVENT SHALL THE AUTHOR OR CONTRIBUTORS BE LIABLE
 * FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
 * DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS
 * OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
 * HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
 * LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
 * OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF
 * SUCH DAMAGE.
 *
compare with galaxy evolution models of massive spheroids. The galaxies in the sample have apparent magnitudes $14.5\lesssim m_r \lesssim 17.5$ (based on deVaucouleur fits to the surface brightness profiles). (The SDSS photometric parameters for these objects have been corrected for known sky subtraction problems which affect bright objects.) Estimated stellar masses and ages for these objects are from @Gallazzi05. These are based on running a likelihood analysis of the spectra that returns a mass-to-light ratio $/L_z$ (defined for a @Chabrier03 initial stellar mass function), which is in turn converted to a stellar mass using the SDSS petrosian $z$-band restframe magnitude (see @Bernardi09b for a comprehensive discussion and comparison of such stellar mass estimates with other methods). Our main results do not change if we use the ages published


fixed mass is approximately $\sim 0.6$ dex for masses below $\sim 3\times 10^{10}$, decreasing at large mass. This behavior in the scatter as a function of stellar mass was already noted by @Shen03, and we here further suggest, after @ShankarBernardi and the discussion below, that this is mainly induced by the different gradients in the size-age relation in different stellar mass bins. The solid contours, the same in each panel, bracket the regions containing 30%, 65%, and 95% of the full sample, respectively.

The orange, green, and blue coloured regions show the corresponding distributions when we restrict the sample to narrow bins in (luminosity-weighted) age. Notice that the older galaxies tend to populate the high-mass end of this relation (the shaded regions peak at higher  in the bottom rightis essentially the same problem we found in Figure \[fig|RezModelsFixedMstar\]; the only difference is that there the galaxies in a given panel were selected to have the same  at all lookback times, whereas here they have the same  only at $z=0$, and we then study their progenitors at earlier times.)

![image](figMineMerg.eps){width="0.9\hsize"}

If the problem with the models is simply the overall normalization of the sizes for a given , then it is interesting to study what aspect of the models produced the flat size-age relation. The first question which arises in this context is what these objects looked like in the past. The red circles in each panel show the sizes, masses and densities (top to bottom) of these objects at the time they formed. The middle panels show that the


common divisor of v and r.
3
Suppose m = -5*d - 20, 88*m - 89*m - 3*d - 10 = 0. What is the highest common factor of 1265 and m?
5
Let v = 186 - 126. Let f be 14/(-105) - (-34088)/v. What is the highest common factor of 71 and f?
71
Suppose 0 = -4*n + 2*y + 18, n - 3*y = 17. Suppose -4*q - n*t + 156 = 0, -4*t = -4*q + 24 + 144. Calculate the highest common divisor of q and 5.
5
Let v be 0 + 0 + 113 + -2. Let u(w) = -2*w**3 - 197*w**2 - 3084*w - 200. Let z be u(-79). Calculate the highest common factor of v and z.
37
Suppose 5106 = 2*p - 3*h, -9*p = -7*p +-1 + (-39)/(-1). What is the greatest common factor of s and f?
4
Suppose 72*o - 2392 - 3782 = -75*o. What is the highest common divisor of o and 861?
21
Let m(k) = -3*k**2 - 30*k + 66. Let i be m(2). Let j(z) = 18*z + 130. Let u be j(i). Calculate the highest common divisor of 66 and u.
22
Let c = -82165 + 115775. Calculate the greatest common divisor of 10 and c.
10
Let t(j) = j**3 - 27*j**2 + 13*j - 51. Suppose -4*z = -4*x - 130 + 18, 3*z = -2*x + 79. Let s be t(z). Calculate the greatest common factor of 15 and s.
15
Let j = 404 + -405. Let m be j*((-12)/(-60) - (-202)/(-10)). What is the greatest common factor of m


use of HIV Env polypeptides in immunogenic compositions has been described. (see, U.S. Pat. No. 5,846,546 to Hurwitz et al., issued Dec. 8, 1998, describing immunogenic compositions comprising a mixture of at least four different recombinant virus that each express a different HIV env variant; and U.S. Pat. No. 5,840,313 to Vahlne et al., issued Nov. 24, 1998, describing peptides which correspond to epitopes of the HIV-1 gp120 protein). In addition, U.S. Pat. No. 5,876,731 to Sia et al, issued Mar. 2, 1999 describes candidate vaccines against HIV comprising an amino acid sequence of a T-cell epitope of Gag linked directly to an amino acid sequence of a B-cell epitope of the V3 loop protein of an HIV-1 isolate containing the sequence GPGR. There remains a need forDisgraced movie producer Harvey Weinstein opened up to Greek journalist Panagiotis “Taki” Theodoracopulos in a “world exclusive,” detailing how offering sex for movies is and always been common in Hollywood.

“You were born rich and privileged and you were handsome,” Weinstein was quoted saying to Theodoracopulos, who said the embattled producer’s attorney, Ben Brafman, was also present during the interview. ” I was born poor, ugly, Jewish and had to fight all my life to get somewhere. You got lotsa girls, no girl looked at me until I made it big in Hollywood.”

“Yes, I did offer them acting jobs in exchange for sex, but so did and still does everyone,” Harvey Weinstein said, adding, “But I never, ever forced myself on a single woman.”

The interview was published just days


Amnesty International Warns of Growing Risk of Civil War in Yemen; Calls on Authorities to Stop Attacks on Peaceful Protesters, as Security Forces Kill Dozens

Press Release

September 19, 2011

Amnesty International Warns of Growing Risk of Civil War in Yemen; Calls on Authorities to Stop Attacks on Peaceful Protesters, as Security Forces Kill Dozens

Contact: Suzanne Trimel, 212-633-4150, strimel@aiusa.org

(New York) -- Yemeni authorities must immediately stop the killing of peaceful protesters by security forces, Amnesty International said today, after dozens of people were shot dead in the capital, Sana'a, since Sunday.

The organization called for an independent, impartial commission of inquiry to be set up with international assistance to investigate the attacks on protesters.

Around 26 people were killed on Sunday. The continuing violence has seen more killed in Sana'a today.

Hundreds more aresaid to have been injured after security forces used snipers and rocket-propelled grenades (RPGs) against protesters marching to demand the resignation of President Ali Abdullah Saleh.

The situation is also worsening in the southern city of Ta'izz after security forces opened fire on protesters marching in solidarity with those killed in Sana'a.

"Yemen is on a knife edge. Those who have been protesting peacefully for change are increasingly frustrated by the political deadlock," said Philip Luther, Amnesty International's deputy director for the Middle East and North Africa.

"Eruptions of violence point to a growing risk of civil war. The Yemeni authorities must stop the use of excessive force before the violence spirals out of control."

Since February 2011 some 200 people have been killed and more than a thousand have been injured


to discover a “good” ordering for given input polynomials during the Gröbner basis computation. Algorithm \[alg: Dynamic Buchberger Algorithm\] describes a **dynamic Buchberger algorithm**. As with the static algorithm, its basic form contains a number of unresolved ambiguities:

------------------------------------------------------------------------

**algorithm** *dynamic\_buchberger\_algorithm*

**inputs:** $F\subseteq R$

**outputs:** $G\subseteq R$ and $\sigma\in{\ensuremath{\mathcal T}}$ such that $G$ is a Gröbner basis of $\ideal{F}$ with respect to $\sigma$

**do:**

1.  Let $G=\left\{ \right\} $, $P=\left\{ \left(f,0\right):f\in F\right\} $, $\sigma\in{\ensuremath{\mathcal T}}$

2.  **while** $P\neq\emptyset$\[enu: while loop of dynamic algorithm\]

    1.  Select $\left(p,q\right)\in P$ and remove it

    2.  \[enu: r full reduction of s(p,q) (dynamic)\]Let $r$ be a remainder of ${\ensuremath{\mathrm{spoly}}}\left(p,q\right)$ modulo $G$

    3.  **if** $r\neq0$

        1.  Add $\left(g,r\right)$ to $P$for all $g\in G\backslash\left\{ r\right\} $, so that $\tau$ refines $\sigma$. This allows the algorithm to discard line \[enu: modify P after new order\] altogether, and this is probably a good idea in general.

\[prop: caboara second optimization\]Let $G=\left\{ g_{1},\ldots,g_{\ell}\right\} \subsetneq R$ and $t_{1},\ldots,t_{\ell}$ be potential leading terms of $g_{1},\ldots,g_{\ell}$, respectively. The system $$\left\{ t_{k}>u:u\in{\ensuremath{\mathrm{supp}}}\left(g_{k}\right)\right\} _{k=1}^{\ell}$$ is equivalent to the system $$\left\{ t_{k}>u:u\mbox{ a PLT of }g_{k}\mbox{ consistent w/}t_{j}=\lt\left(g_{j}\right)\;\forall j=1,\ldots,k-1\right\} _{k=1}^{\ell}.$$

Proposition \[prop: caboara second optimization\] implies that we need only compare $t_{k}$ with other potential leading terms $u$ of $g_{k}$ that are consistent with the previous choices; we will call such $u$, **compatible leading terms**.[^1] From a practical point of view, refining the cone in this way is a good idea, as the technique of refining the order allows one to


x^{2},xy\right\} $ and $\lt[\tau]\left(G\right)=\left\{ y^{2},xy\right\} $. Suppose we choose $\sigma$ and compute the $S$-polynomial. This adds $r=y^{3}+x-4y$ to the basis, and the cone containing $\sigma$ splits, giving us two choices for $\lt\left(r\right)$. ](circle_hyperbola_cones_split "fig:")

Even though *some* cones *can* split when we add new polynomials, not *all* clones *must* split. In particular, the cone containing the desired ordering need not split, especially when the algorithm is nearly complete. For this, reason, it is not necessary to refine the cone every time a polynomial is added. The methods of the next section help detect this situation.

\[sec: ideas\]Exploiting the narrowing cone
===========================================

The main contribution of this paper is to use the narrowing cone to switch the refiner on and off. We propose two techniques to accomplish this: one keeps track of conesto the expense of building a linear program to check whether $C_{v}\cap C_{T'}\neq\emptyset$.

### Algebraic implementation

We could determine whether $C_{v}\subseteq C_{u}$ by building a linear program, but we will content ourselves with determining when one set of inconsistent linear constraints is a subset of another set.

Let $L_{T}$, $L_{U}$, and $L_{V}$ be sets of linear constraints. If $L_{T}$ is inconsistent with $L_{U}$ and $L_{U}\subseteq L_{V}$, then $L_{T}$ is also inconsistent with $L_{V}$.

Assume $L_{T}$ is inconsistent with $L_{U}$ and $L_{U}\subseteq L_{V}$. The first hypothesis implies that $L_{T}\cap L_{U}=\emptyset$. The second implies that $L_{V}$ has at least as many constraints as $L_{U}$, so that the feasible regions $C_{U}$ and $C_{V}$, corresponding to $L_{U}$ and $L_{V}$, respectively, satisfy the relation $C_{U}\supseteq C_{V}$. Putting it all together, $C_{V}\cap C_{T}\subseteq C_{U}\cap C_{T}=\emptyset$.

In our situation, $L_{U}$


we pointed out that creating constraints only for the terms identified as potential leading terms by the use of boundary vectors can lead to an inconsistency with previously-chosen terms. For this reason, we not only try to solve the linear program, but invokes algorithm *monitor\_lts* (Figure \[alg: ensuring monomials invariant\]) to verify that previously-determined leading terms remain invariant.

------------------------------------------------------------------------

**algorithm** *monitor\_lts*

**inputs**

-   $G$, the working basis

-   $\sigma\in{\ensuremath{\mathcal T}}$, the old ordering

-   $\tau\in{\ensuremath{\mathcal T}}$, a new ordering

-   $L={\ensuremath{\mathrm{mlp}}}\left(\tau,G\right)$

**outputs**

-   (`True`, $\mu$) if there exists $\mu\in L$ refining $C\left(G,\sigma\right)$ and $\lt[\mu]\left(g_{\textrm{last}}\right)=\lt[\tau]\left(g_{\textrm{last}}\right)$, where $g_{\textrm{last}}$ is the newest element of $G$

-   `False` otherwise

**do:**

1.  let $\mu=\tau$

2.  **while** there exists $g\in G$ such that $\lt[\mu]\left(g\right)\neq\lt[\sigma]\left(g\right)$

    1.  **for each** $g\in G$ whosethe leading term. Thus, it returns (`True`, $\mu$) if and only if it is possible to build a linear program $L$ whose solution $\mu$ lies in the non-empty set $C\left(\tau,G\right)\cap C\left(\sigma,G\right)$.

It remains to put the pieces together.

------------------------------------------------------------------------

**algorithm** *dynamic\_algorithm\_with\_geometric\_criteria*

**inputs:** $F\subseteq R$

**outputs:** $G\subseteq R$ and $\sigma\in{\ensuremath{\mathcal T}}$ such that $G$ is a Gröbner basis of $\ideal{F}$ with respect to $\sigma$

**do:**

1.  Let $G=\left\{ \right\} $, $P=\left\{ \left(f,0\right):f\in F\right\} $, $\sigma\in{\ensuremath{\mathcal T}}$

2.  Let $\textit{rejects}=\left\{ \right\} $, $\Psi=\left\{ e_{k}:k=1,\ldots,n\right\} $

3.  **while** $P\neq\emptyset$\[enu: while loop of dynamic algorithm-1\]

    1.  Select $\left(p,q\right)\in P$ and remove it

    2.  \[enu: r full reduction of s(p,q) (dynamic)-1\]Let $r$ be a remainder of ${\ensuremath{\mathrm{spoly}}}\left(p,q\right)$ modulo $G$

    3.  **if** $r\neq0$


standard degree;

-   `use_boundary_vectors`: boolean, default is `True`;

-   `use_disjoint_cones`: boolean, default is `True`.

At the present time, we are interested in structural data rather than timings. To that end, experimental data must establish that the methods proposed satisfy the stated aim of reducing the size and number of linear programs constructed; in other words, the algorithm invokes the refiner only when it has high certainty that it is needed. Evidence for this would appear as the number of linear programs it does *not* construct, the number that it *does*, and the ratio of one to the other. We should also observe a relatively low number of failed linear programs.

Table \[tab: comparison dyn, static\] summarizes the performance of this implementation on several benchmarks. Its columns indicate:

-  become more congested due to your neighbors. Use tools such as Ekahau HeatMapper or Wi-Fi Analyzer for Android to find a clean channel.

4. 5 GHz is your favorite band: Your Wi-Fi router / access point likely operates on two main frequency bands at the same time: 2.4 GHz and 5 GHz. Client devices (laptops, smartphones, tablets, etc.), only use one frequency or the other at a time but likely can choose which one they decide to use at any time. The 2.4 GHz frequency band has just three interference-free channels (numbers 1,6,11). The 5 GHz band has a lot more. Thus, it’ll be easier to find a clean channel from the 5 GHz spectrum.

The client may not know what’s “best for itself”. In other words, the client device


The forte SFP-based 10/100/1000M Gigabit Ethernet Media Converter series designed to meet the needs for network deployment.

It can extend a copper-based Gigabit network via fibre cable over 120+ km. Our Gigabit Ethernet Media Converter series is fully compliant with IEEE802.3/8 02.3u/802.3ab/802.3z, 10/100/1000Base- TX, and 1000Base-FX standards. The 415021 has an operating temperature of -10°C to 60°C which makes it suitable for a wide range of environmentsQ:

Best practices to use when targeting multiple screen resolutions on Android

When designing an UI, we need to target many android mutations and various screen resolutions.

How to differentiate layout for 480 * 800 and 480 * 854 screen resolutions in android?
how to layout support for various screen in android?

Both questions above recommend to use different Layout code for different screens. Is it really necessary?

http://developer.android.com/guide/practices/screens_support.html

recommends to

Provide different layouts for different screen sizes
Provide different bitmap drawables for different screen densities

But I still think, we can support multiple screens without creating standalone layout for each screen resolution. Or am I wrong?
I know, and I do use, 9-patch for scalable background images (or form inputs, and so on)
and I do use dp (density pixel) to declare sizes relatively to screen density
But what are


investigated the crystallographic, transport, and magneto-transport properties of Ru$_{1-x}$Ir$_{x}$Sr$_{2}$Gd$_{1}$Cu$_{2}$O$_{8}$ compound in order to study the relationship between superconductivity and magnetism. We have found that Ir substitutes Ru up to 10 % in Ru-1212 without appreciable structural changes. In addition to this, the combined data indicate a possible phase-separation in the Ru-1212 compound.

Experimental Procedure {#experimental}
======================

Polycrystalline samples of Ru$_{1-x}$Ir$_{x}$Sr$_{2}$GdCu$_{2}$O$_{8}$ (Ru(Ir)-1212);0 $\leq$ *x* $\leq$ 0.10; were prepared following a two-step procedure.[@15] The two-step synthesis minimizes the formation of the SrRuO$_{3}$ phase, yielding samples with better quality.[@16] Initially, the Sr$_{2}$GdRu$_{1-x}$Ir$_{x}$O$_{6}$ (Sr-2116) precursor was prepared by mixing stoichiometric quantities of high purity Ru, Ir, SrCO$_{3}$, and Gd$_{2}$O$_{3}$, grinding together and heating in air at 1250 $^\circ$C for 12 h. Then, CuO was mixed to the Sr-2116 powders, ground together, pressed into pellets, andable to infer that the magnitude of the magnetic moment decreases with increasing Ir concentration. The latter result, combined with the gradual decrease of *T$_{M}$* with increasing Ir content, is compelling evidence that Ir does replace Ru in this series. In the lower inset of Fig. 3, *T$_{M}$* as a function of Ir content is displayed. The results indicate that *T$_{M}$* decreases linearly with Ir content at the rate of $\sim$ -1.6 K/Ir at %. Values of *T$_{M}$* are summarized in Table II.

The suppression of the diamagnetic signal in Ru(Ir)-1212 at very low applied magnetic fields $\sim$ 5 Oe is of interest and has been discussed previously for similar compounds.[@9] It was argued that these oxides are comprised of two different phases due to a phase separation phenomenon:


Ir; for *H* = 0, the transition temperature decreases from $\emph{T$_{1}$}$ $\sim$ 39 K ($\emph{x =}$ 0.00) to $\emph{T$_{1}$}$ $\sim$ 22 K ($\emph{x =}$ 0.10). The value of *T$_{1}$* is nearly magnetic field independent *H* up to 0.5 T. However, two features in the *H* $\sim$ 0.035 - 0.500 range are of interest: (i) the reduction in the peak intensity; and (ii) a pronounced broadening of the peaks, culminating in a split into two convoluted peaks. A further increase in *H* $\geq$ 0.5 T results in a progressive reduction of the amplitude of the high temperature peak, leading to its gradual suppression, and the appearance of another peak at low temperatures for applied magnetic fields $\emph{H}$ $\sim$ 1 - 2 T. The amplitude of the peak at lower). A. C. McLaughlin, and J. P. Attfield, Phys. Rev. B [**60**]{} (1999) 14605. A. Hassen, J. Hemberger, A. Loidl, and A. Krimmel, Physica C [**400**]{} (2003) 71. G. V. M. Williams, Ho Keun Lee, and S. Krämer, Phys. Rev. B [**67**]{} (2003) 104514. Z. Sun, S. Y. Li, Y. M. Xiong, and X. H. Chen, Physica C [**349**]{} (2001) 289. See, for instance, T. P. Papageorgiou, T. Herrmannsdorfer, R. Dinnebier, T. Mai, T. Ernst, M. Wunschel, and H. F. Braun, Physica C [**377**]{} (2002) 383; R. F. Jardim, E. A. Early, and M. B. Maple, J. Alloys Comp. [**221**]{} (1995) 1. S. Andrade, F. C. Fonseca, R. F. Jardim, I. Bossi, M. S. Torikachvili, A. H. Lacerda, and L. Ben-Dor, Braz. J. Phys. [**33**]{} (2003) 686. R.


Z. Cao, Phys. Rev B [**63**]{} (2001) 64506. C. Attanasio, C. Coccorese, V. N. Kushnir, L. Maritato, S. L. Prischepa, and M. Salvato, Physica C [**255**]{} (1995) 239. T. T. M. Palstra, B. Batlogg, R. B. van Dover, L. F. Schneemeyer, and J. V. Waszczak, Phys. Rev. B [**41**]{} (1990) 6621. G. Blatter, M. V. Feigel’man, V. G. Geshkenbein, A. I. Larkin, and V. M. Vinokur, Rev. Mod. Phys. [**66**]{} (1994) 1125. T. T. M. Pastra, B. Batlogg, R. B. van Dover, L. F. Schneemeyer, and J. V. Waszczak, Appl. Phys. Lett. [**54**]{} (1989) 763. *Introduction to Superconductivity and High-TC Materials*, edited by M. Cyrot and D.Pavuna ( World Scientific, Singapore, 1992 ).

[**Figure Captions**]{}\
Figure 1: XRD patterns taken at room temperature of polycrystalline samples of Ru$_{1-x}$Ir$_{x}$Sr$_{2}$GdCu$_{2}$O$_{8}$;*x* = 0.00of the magnet (H $\sim$ 1 Oe). Upper inset: temperature dependence of the in-phase component of the $\chi_{ac}$(T) near the magnetic ordering temperature *T$_{M}$*. Lower inset: plot of the *T$_{M}$* as a function of the Ir content.\
Figure 4: Electrical resistivity versus temperature at several applied magnetic fields to 18 T for the Ru$_{1-x}$Ir$_{x}$Sr$_{2}$GdCu$_{2}$O$_{8}$; *x* = 0.00 and *x* = 0.10; compounds. The remnant field of the superconducting magnet has been estimated to be 0.03 T.\
Figure 5: Temperature dependence of the derivative of the electrical resistivity for the compound Ru$_{0.98}$Ir$_{0.02}$Sr$_{2}$GdCu$_{2}$O$_{8}$ in applied magnetic fields up to 18 T. The upper inset displays a plot of *d$\rho$/dT* versus temperature at *H* = 14 T in samples with Ir concentrations *x* = 0.00, *x* = 0.05, and *x* = 0.10.\
Figure 6:


α,β-unsaturated aldehyde moiety, such as (−)-perillaldehyde (**2ak**) and (−)-myrtenal (**2al**). The corresponding vinylogous products (**5ak**, **5ak′**, **5al,** and **5al′**) were obtained in moderate yields with high diastereoselectivity. It is evident that in the case of (−)-myrtenal with (*S*)-DTBM-SEGPHOS, mismatch phenomenon was observed. The absolute configuration of **5a** was assigned to be *R* by its transformation to a known compound (for details, see [Supplemental Information](#mmc1){ref-type="supplementary-material"}). Analogically, the stereochemistry of other products was dictated tentatively. It should be pointed out that the gram-scale syntheses of both **3a** and **5a** were successfully carried out with constant results. Moreover, it should be mentioned that aliphatic aldehydes afforded α-adducts mainly in low yields at the present reaction conditions, which is a limitation of the present reactions. However, the vinylogous products of aliphatic aldehydes        using (SqlCommand command = new SqlCommand("UPDATE Messages SET NewMessageCount=@NewMessageCount", connection))
                {
                    command.Parameters.AddWithValue("@NewMessageCount", totalNewMessages);
                    command.Notification = null;
                    DataTable dt = new DataTable();
                    SqlDependency dependency = new SqlDependency(command);


Q:

Max size of varchar(max) in SQL Server 2000

I would like to know what is the maximum size of varchar in SQL Server 2000. While I was googling somewhere it was written 8000 characters and somewhere it was written 8060 bytes. Which one is correct?

A:

Varchar is 8000 and nvarchar is 4000.
Here's the varchar msdn reference:
http://msdn.microsoft.com/en-us/library/aa258242(SQL.80).aspx

A:

A SQL Server data page has 8k: 8192 bytes. From this a portion is reserved for the page header, leaving 8060 bytes the maximum lnegth a single row can have. In a row, the varbinary(n), varchar(n) and nvarchar(n) types cannot exceed 8000 bytes, which means that varchar(8000) is the maximum Ascii length and nvarchar(4000) is the maximum Unicode length (since Unicode stores each character on 2 bytes).
The best explanation of all these details comes frompolitical issues and social movements.

Negative stereotypes about activists can negatively affect opinions about a given political issue once the issue is associated with activism. Consequently, because the term repels many people, it cognitively blocks their entry into collective action.

Yet, some people are attracted to activism for that very reason. Many activists take pride in activism partly because it is an expression of their willingness to do something that is unpopular. Indeed, some come to see their own marginalization as a badge of honor, as they carve out a radical oppositional niche identity.

This clustering of activists into silos fits into a broader trend in advanced capitalist nations toward greater individualistic self-expression and less civic participation. With this backdrop, it is as if activism has morphed into a specific identity


(this.elements == null) {
					this.elements = new ArrayList();
				}
				this.elements.add(element);
			}
			root = (IPackageFragmentRoot) element.getAncestor(IJavaScriptElement.PACKAGE_FRAGMENT_ROOT);
			projectPath = root.getJavaScriptProject().getPath().toString();
			String relativePath;
			if (root.getKind() == IPackageFragmentRoot.K_SOURCE) {
				containerPath = root.getParent().getPath();
				relativePath = Util.relativePath(getPath(element, false/*full path*/), 1/*remove project segmet*/);
			} else {
				containerPath = root.getPath();
				relativePath = getPath(element, true/*relative path*/).toString();
			}
			containerPathToString = containerPath.getDevice() == null ? containerPath.toString() : containerPath.toOSString();
			add(projectPath, relativePath, containerPathToString, false/*not a package*/, null);
	}

	if (containerPath != null)
		addEnclosingProjectOrJar(containerPath);
}

/**
 * @param exclusionsPaths
 */
private void addExclusions(IPath containerPath, IPath[] exclusionsPaths) {

	this.exclusionPathList.put(containerPath.toString(), exclusionsPaths);
}

public boolean shouldExclude(String container, String resourceName) {
	boolean shouldExclude = false;

	if(container==null  || resourceName==null || exclusionPathList.size()==0) return false;

	IPath[] exclusions = (IPath[])exclusionPathList.get(container);
	if(exclusions==null) return false;
	IPath fullPath = new Path(container + "/" + resourceName); //$NON-NLS-1$

	for(int i=0;!shouldExclude && i<exclusions.length;i++) {
		shouldExclude = Util.isExcluded(fullPath, null, new char[][] {exclusions[i].toString().toCharArray()});
	}

	return shouldExclude;
}

/**
 * Adds the given path to this search scope. Remember if subfolders need to be included
 * and associated access restriction as well.
 */
private void*/
public boolean encloses(String resourcePathString) {
	int separatorIndex = resourcePathString.indexOf(JAR_FILE_ENTRY_SEPARATOR);
	if (separatorIndex != -1) {
		// internal or external jar (case 3, 4, or 5)
		String jarPath = resourcePathString.substring(0, separatorIndex);
		String relativePath = resourcePathString.substring(separatorIndex+1);
		return indexOf(jarPath, relativePath) >= 0;
	}
	// resource in workspace (case 1 or 2)
	return indexOf(resourcePathString) >= 0;
}

/**
 *
Returns paths list index of given path or -1 if not found.
 * If there are multiple paths in the index that enclose the given path,
 * the index for the most specific enclosing path will be given.

 *
 * NOTE: Use indexOf(String, String) for path inside jars
 *
 * @param fullPath the full path of the resource, e.g.
 *   1. /P/src/pkg/X.js
 *   2. /P/src/pkg
 */
private int indexOf(String fullPath) {
	// cannot guess the index of the container path
	// fallback to


Introduction {#sec1-1}
============

Diabetes is the most prevalent metabolic disorder in humans and affects approximately 8.3% of the adult population worldwide (Shi and Hu, 2014). Diabetes is characterized by high blood glucose levels over a prolonged period. This hyperglycemia produces many clinical symptoms because of the resultant damage to various organs, including the brain. In the brain, diabetes reduces the ability of neurons to adapt to oxidative and metabolic stress (Kapogiannis and Mattson, 2011). In addition, diabetes can cause stroke and worsen episodic memory impairment (Messier, 2005) and synaptic plasticity deficits. Increasing evidence shows that oxidative stress is an important pathway through which several diseases, including diabetes, exert their deleterious effects (Rains and Jain, 2011).

There is a growing body of evidence demonstrating that the glycation toxicity caused by hyperglycemia elicitsthe generation of excess reactive oxygen species (ROS) and nitric oxide in neurons. Brain tissue is highly susceptible to ROS because it has a high rate of oxidative metabolic activity, high concentration of polyunsaturated fatty acids in membrane lipids, and low antioxidant capacity (Fukudome et al., 2008; Nishikawa et al., 2000). Once a radical is formed, propagation can lead to increasing levels of damage. The highly reactive hydroxyl radical, in turn, can cause lipid peroxidation and DNA damage (Robb-Gaspers and Connor, 1997). In diabetic patients, oxidative and nitrosative stress is increased, which can damage cellular proteins, lipids, and DNA, thereby inhibiting their normal functions and disturbing homeostasis within the neurons, ultimately resulting in cell death (Paradies et al., 2011).

Antioxidant-like protein-1 (AOP-1) was first identified as a molecule exhibiting


temporal changes of AOP-1 expression and oxidative stress-induced protein modification in the hippocampus of rats with STZ-induced type 1 diabetes.

Materials and Methods {#sec1-2}
=====================

Experimental animals {#sec2-1}
--------------------

7-week-old male Wistar rats, weighing 190--200 g, were purchased from Orient Bio, Inc. (Seongnam, South Korea). They were housed at 23°C with 60% humidity and a 12-hour light-dark cycle, with free access to food and tap water. Animal handling and care conformed to guidelines established to comply with current international laws and policies (NIH Guide for the Care and Use of Laboratory Animals, NIH Publication No. 85-23, 1985, revised 1996), and were approved by the Institutional Animal Care and Use Committee (IACUC) of Seoul National University. All of the experiments and procedures were designed to minimize the number of animals used and the suffering(pH 7.2) and mounted on gelatin-coated slides. Sections were mounted in Canada Balsam (Kanto, Tokyo, Japan) following dehydration.

The number of AOP-1-immunoreactive cells in each section of the hippocampal CA1, 3 region and dentate gyrus was counted using an image analysis system (Optimas 6.5, CyberMetrics, Scottsdale, AZ, USA) equipped with a computer-based CCD camera. The cell counts from all sections of all rats were averaged.

Indirect measures of oxidative stress {#sec2-5}
-------------------------------------

To elucidate the effects of STZ on protein modification, the carbonylation of proteins by oxidative stress was determined in control and STZ-treated rats at 2, 3 and 4 weeks after STZ treatment (*n* = 5 in each group) by the Levine method (Levine et al., 1990). The color intensity of the supernatant was measured using a spectrophotometer (Agilent, Sata Clara,


R1 reagent (1:3 of methanol:N-methyl-2-phenylindole) were added and mixed with 150 μL of 12 N HCl. Each reaction was incubated at 45°C for 60 minutes and centrifuged at 10,000 × g for 10 minutes. The supernatant was collected and MDA formation was determined by measuring the absorbance at 586 nm. MDA data were normalized to the protein concentration.

Statistical analysis {#sec2-6}
--------------------

The data shown here are expressed as the mean ± SEM and were analyzed by using GraphPad Prizm 5.0 software (GraphPad Software Inc., La Jolla, CA, USA) and differences between groups were statistically analyzed by one-way analysis of variance followed by Bonferroni\'s *post-hoc* analysis.

Results {#sec1-3}
=======

Changes in blood glucose levels {#sec2-7}
-------------------------------

In the control group, the mean fasting blood glucose level was 5.85 mM. The blood glucose level significantly increased to(Biessels et al., 1996). In the present study, we induced type 1 diabetes with 75 mg/kg STZ in rats because administration of 75 mg/kg STZ influences the Km values and Vmax of tryptophan-5-hydroxylase in the brain (Herrera et al., 2005). Reactive oxygen species, which are formed during oxidative stress, induce cellular and molecular abnormalities in the hippocampus of STZ-treated rats. In addition, the accumulation of ROS causes an imbalance between their production and removal by the antioxidant system, which finally leads to an increase in DNA oxidation and lipid peroxidation in neurons.

We first measured blood glucose levels 3 days after STZ treatment and excluded rats showing low fasting blood glucose levels lower than 8.00 mM because some of these rats did not show any significant increase in blood


glucose levels after STZ treatment. At 2--4 weeks after STZ treatment, the blood glucose levels were higher than 20 mM. We used these rats for AOP-1 immunohistochemistry and for biochemical analysis. AOP-1 immunoreactivity was predominantly observed in the non-pyramidal cells of the CA1, 3 regions or neurons of the dentate gyrus. This result is consistent with our previous study where AOP-1 was primarily found in non-pyramidal cells through double immunofluorescent labeling for AOP-1 and glutamic acid decarboxylase 67 or parvalbumin, which are markers for GABAergic neurons (Hwang et al., 2005). The number of AOP-1 immunoreactive neurons decreased in the hippocampal CA1, 3 regions, but not in the dentate gyrus, 2--4 weeks after STZ treatment. These spatial and temporal changes of AOP-1 suggest that AOP-1 immunoreactive neurons in theShare this:

President Donald Trump’s re-election campaign used a photo of a survivor of the Parkland, Florida, shooting in an email Saturday that asks its recipients to donate money to the campaign.

The email contains a photo of 17-year-old Madeleine Wilford in a hospital bed surrounded by her family, Trump and the first lady. The President visited Wilford on February 16, two days after the attack at Marjory Stoneman Douglas High School, which left 17 dead.

“The nation has turned its attention to the senseless school shooting in Parkland, Florida,” the email reads.

“Trump is taking steps toward banning gun bump stocks and strengthening background checks for gun purchasers,” it says. “The President has made his intent very clear: ‘making our schools and our children safer will be our top priority.'”

Near the


which the transfer layer 5' is to be laminated. As a result, a non-adhered portion between the substrate 6 and the transfer layer 5' is enlarged to cause a problem that sufficient production yield cannot be obtained.
Various means to cope with the problems as described above have been proposed. For example, a method of coating water on a base material and then laminating a laminate film on the base material has been described (see Japanese Provisional Patent Publications No. 21890/1982 and No. 21891/1982).
In this method, in order to adhere a thin water layer to the base material uniformly, the surface of the base material should be cleaned. When through holes with a small size or the like exist in the base material, water held in the through holesare accurate to 0.1$''$ rms or better in each coordinate; the largest expected errors are 0.2$''$ (see Pier et al 2003). The SDSS coordinates are placed in the International Celestial Reference System, primarily through the USNO CCD Astrograph Catalog (Zacharias et al. 2000), and have an rms accuracy of 0.045$''$ per coordinate.

4\) The quasar redshifts. A total of 377 of the CAS redshifts were revised during our visual inspection. A detailed description of the redshift measurements is given in Section 4.10 of Stoughton et al. (2002). A comparison of 299 quasars observed at multiple epochs by the SDSS (Wilhite et al. 2005) finds an rms difference of 0.006 in the measured redshifts for a given object. 5–14) The DR3 PSF magnitudes and errors (not corrected for Galactic reddening) from BEST photometry (or, when BEST is unavailable, from


column 17 or 20 that also have at least one FIRST counterpart located between 2.0$''$ (the SDSS-FIRST matching radius) and 30$''$ of the optical position. Based on the average FIRST source surface density of 90 deg$^{-2}$, we of these matches to be chance superpositions.

22\) The logarithm of the vignetting-corrected count rate (photons s$^{-1}$) in the broad energy band in the [*ROSAT*]{} All-Sky Survey Faint Source Catalog (Voges et al. 2000) and the [*ROSAT*]{} All-Sky Survey Bright Source Catalog (Voges et al. 1999). The matching radius was set to 30$''$; an entry of “$-9.000$" in this column indicates no X-ray detection.

23\) The S/N of the [*ROSAT*]{} measurement.

24\) Separation between the SDSS and [*ROSAT*]{} All-Sky Survey coordinates (in arc seconds).

25–30) The $JHK$ magnitudes and errors from the 2MASS All-Sky Data Release Point Source Catalog (Cutri et al. 2003)certain (as we thought we were when using the DR1 database) of the celestial positions.

5\. The positions of two DR1 quasars, whose spectra were taken on spectroscopic plate 540, changed by more than one arcsecond (in these cases, 2.0$''$ and 3.5$''$) in the DR3 database.

Four of the entries in the DR3 catalog have redshifts that differ by more than 0.1 from the DR1 values (the changes in redshift are large: 0.52, 0.84, 1.44, and 2.33). These quasars are reviewed in §5.10. Only seven quasars have $i$ measurements that differ by more than 0.5 magnitudes between DR1 and DR3. In all cases the DR3 measurements are considered more reliable than those presented in previous publications.

Bright Quasars
--------------

Although the spectroscopic survey is limited to objects fainter than , the SDSS continues to discover “PG-class" (Schmidt &


Green 1983) objects. The DR3 catalog contains 56 entries with ; seven were previously unknown. The spectra of the brightest two discoveries, , and , , are presented in Figure 1. Six of the seven new bright quasars have redshifts below 0.2 and are in the low-luminosity tail of the catalog see Figure 5); but the $z$ = 2.21 object is spectacularly luminous (see §5.3). A comparison of the SDSS and PG surveys is presented in Jester et al. (2005).

Luminous Quasars
----------------

There are 68 catalog quasars with (3C 273 has in our adopted cosmology); 25 are published here for the first time. HS 1700+6416, at is the most luminous quasar in the catalog. Four objects have , including (see previous section), which, at is the third most luminous catalog entry. The spectrum of this object possesses a numberwith redshifts greater than or equal to 4.99) are displayed in Figure 6.

The processed spectra for a few of the high-redshift quasars have gaps (usually caused by extreme contamination of the spectrum from bright, neighboring objects) that include all of the region containing the Lyman $\alpha$ emission line. The shape of such spectra (in particular the region associated with the Lyman $\alpha$ forest), however, are so distinctive that we are confident that our redshift assignments are correct. To verify that this is an appropriate procedure, we obtained a spectrum with the Low Resolution Spectrograph (Hill et al. 1998) on the Hobby-Eberly Telescope (HET) of the highest redshift quasar with this defect in the SDSS spectrum: The HET spectrum confirmed that this is indeed a redshift 4.9 quasar.

The flux limits of the RASS are such


the powder melts, flows into a continuous phase and solidifies when the mold cavity is subsequently cooled (all without the application of pressure). This process has proved to be quite successful in producing relatively satisfactory articles at very low costs.
The electrostatic spray process has, however, been used successfully only with polymeric materials which soften at relatively low temperatures such as polyethylene and polyvinyl chloride. Polymeric materials which are stable at higher temperature, such as polyethylene terephthalate, have not been used successfully in the electrostatic spray process. In fact it has not, insofar as is known, been possible heretofore to prepare ovenable articles utilizing this process.to pour rain (not for comic effect, it’s really raining on him to make us more emotionally involved).

The nail in the coffin is the role Marisa Tomei has, a one-night-stand of Carell who seems just out for a wild ride and gets off on his plain honesty about still being in love with his wife and yet who throws a fit in the middle of a parent-teacher conference over how he never called again. Fake, lame, hyper, and trying to get a reaction from the audience with manipulative garbage we’ve seen in pretty much every other get-her-back rom-com, “Crazy Stupid Love” teases with aspects like a simply perfect Emma Stone while gorging us on insightful lines by a thirteen-year-old who’s in love with a girl because he’s jacking


weights, red blood cell count, hematocrit, mean corpuscular hemoglobin and hemoglobin were observed at 200mg/kg in females. In males, this extract decreased white blood cell count, lymphocytes and relative weight of seminal vesicles and ventral prostate at 200mg/kg. The aqueous extract of Myrianthus arboreus leaves was non-toxic in acute administration and exhibited a relatively low toxicity potential on accessory sex organs in both sexes, and leukocytes in males following the repeated 28-days oral administration of the dose 200mg/kg.abandoned and filled with water. While the Shanghai Metro was put into service in 1995, the economic decline of Shenyang during the 1980s-1990s meant that there was no capital available for subway construction and the program was continually postponed.

A light rail system was designed in the early 1990s as a cheaper alternative, however this plan was also abandoned after a national suspension of subway projects was declared due to worries of high cost and financial debt.

Shenyang's economy revived in 2000, and with it growing traffic congestion and pollution caused by the expanding urban population. This prompted the Chinese central government to approve the subway proposal on November 8, 2005. Construction of the first phase of Line 1 started on November 18, 2005 with the entire phase opened on


of “extreme” weather events are being seen worldwide as our climate warms. Maybe one of the scenarios above could be one of them.

Jan Null, meteorologist and private consultant, Golden Gate Weather Services

This is a dry year after a wet year, and actually since the middle of 2015 or so, we’ve been alternating dry-wet, dry-wet, and if you average those years together, you get average. The stress level depends on who you are.

If you’re a farmer in the San Joaquin Valley coming out of the drought from the early-2010s, the ground water hasn’t been replenished in those areas. You’re going to be more stressed than a farmer in the Sacramento Valley, where ground water wasn’t drawn down as much. If you’re a water district manager, you’re going to beNew members of the Minnesota Wild join in on the Skol chant at the Vikings season opener

The NFL is finally back and fans across North America couldn’t be happier.

The first Monday night of the season features a double header with the opening game taking place in Minnesota between the Vikings and the New Orleans Saints.

The Vikings got off to a great start in their season opener as they jumped out to a 16-6 lead in the first half and the crowd got behind them right from the get-go, including Minnesota Wild players Tyler Ennis, Landon Ferraro and Marcus Foligno.

All three players recently joined the Wild organization this past offseason and were checking out the stadium for the first time.

Unbelievable new stadium here. Great atmosphere!!! https://t.co/NnupauPvA8 — Landon Ferraro


Senate Committee on Indian Affairs Legislative Hearing to receive testimony on the following bills: S. 2636, S. 3216, S. 3222, S. 3300 Date: 09/14/2016 02:30 PM Location: Dirksen 628 Type: Legislative Hearing S. 2636, a bill to amend the Act of June 18, 1934, to require mandatory approval of applications for land to be taken into trust if the land is wholly within a reservation, and for other purposes; S. 3216, a bill to repeal the Act entitled “An Act to confer jurisdiction on the State of Iowa over offenses committed by or against Indians on the Sac and Fox Indian Reservation”; S. 3222, To authorize the Secretary of the Interior to assess sanitation and safety conditions at Bureau of Indian Affairs facilities that were constructed to provideAs firefighters emerge from another record wildfire season in the Western United States, University of California, Berkeley, scientists say it’s time to give them a 21st century tool: a fire-spotting satellite.

An artist’s concept of the FUEGO satellite, which would snap digital photos of the Western U.S. every few seconds in search of hot spots that could be newly ignited fires. Image by R. E. Lafever, Lawrence Berkeley National Laboratory.

Such a satellite could view the Western states almost continuously, snapping pictures of the ground every few seconds in search of hot spots that could be newly ignited wildfires. Firefighting resources could then be directed to these spots in hopes of preventing the fires from growing out of control and threatening lives and property.

The UC Berkeley scientists have designed such


"Mozilla Messaging has published a proposed schedule for Thunderbird 3.1, the next release of the popular e-mail client. The organization is refining its development process and could potentially shift towards shorter release cycles and a more incremental approach to development.

"Mozilla Messaging, the Mozilla subsidiary behind the Thunderbird project, has revealed a preliminary roadmap proposal for the next major version of the open source e-mail client. The developers could potentially adopt a more incremental development model with shorter release cycles.

"According to a new proposed schedule that has been published in the Mozilla wiki, Thunderbird 3.1 is tentatively planned for release in April. The new version will include an updated Gecko engine and some features that weren't quite ready for the 3.0 release. The roadmap states that large and disruptiveCowpox virus infection: an emerging health threat.
Human cowpox, a rare zoonotic infection, evokes a self-limited disease, except for immunocompromised and eczematous patients, particularly children, where it can become severe. The causative agent, cowpox virus, is distributed in Europe, west former USSR, and adjacent areas of Northern and Central Asia, with an increasing number of reports in Europe. The purpose of this paper is to review cowpox with an emphasis on its epidemiology and management. Numerous reports of human cowpox affecting young people in Europe indicate that lack of smallpox vaccination, which has been abandoned since 1977, may render the population more vulnerable to cowpox virus. The ownership of wild and exotic animal pets is becoming more popular, and the range of recognized wild and domestic animal hosts is


wall of the casing or the pipeline, after which it is hardened.
The wall of the preform is usually made from a thermosetting resin reinforced with fibers and hardened is achieved by heating (by the Joule effect or by means of a hot liquid introduced into the preform).
This method is satisfactory.
However, there is not always a good seal between the lining and the borehole, the casing or the pipeline around it.
In some cases liquids or gases in the soil can pass through perforations or other openings in the wall of the borehole, casing or pipeline, finding their way into the annular space between the lining and the borehole, casing or pipeline, and eventually flowing into the interior of the latter.
The pressure of the liquid or the gas in thisannular space, even if it has a size on the micrometer scale, firstly causes the lining to contract and secondly causes the borehole, casing or pipeline to expand, so increasing the size of said annular space and degrading the seal.
To our knowledge there is no simple method of achieving a good seal at this location.
An object of the present invention is to propose such a method.


Introduction {#Sec1}
============

Bluetongue virus (BTV) represents the type species of the *Orbivirus* genus, family *Reoviridae* and causes bluetongue disease (BT) in susceptible species \[[@CR1], [@CR2]\]. BTV is usually transmitted to domestic and wild ruminants by the bite of haematophagous female midges of the *Culicoides* genus yet direct transmission was demonstrated at least for serotype 26 \[[@CR3]\]. From 1998 to 2006, Europe had to face an unprecedented emergence of BTV serotypes 1, 2, 4, 9 and 16 (BTV1, 2, 4, 9, 16) throughout the Mediterranean Basin, including several countries where the virus was never detected before. August 2006 is a tipping point in BTV epidemiology, with a first detection of BTV8 in Europe Mainland \[[@CR4]\] and a subsequent wide spread throughout Europe during the following 2 years. BTV8 emergence was easilyspread through Culicoides species that were not known as the historic BTV transmission species, i.e. *Culicoides obsoletus* complex species \[[@CR5]\]. This epidemic---affecting abundantly cattle whereas previous outbreaks largely occurred in small ruminants---is considered to have caused greater economic damage than any previous single serotype outbreak \[[@CR6]\]. Most of the countries involved in the beginning of the BTV8 epidemic and that paid the heaviest toll were declared bluetongue-free in 2012 (Belgium, the Netherlands, Germany, France \[[@CR7], [@CR8]\]).

Bluetongue virus virulence and transmission potential is not serotype driven thus outcome of the infection cannot be predicted based on the serotype alone \[[@CR9]\]. Within a serotype, the geographical origin can be used to define topotypes with different pathogenicity. As an example, some Australian strains were reported to be less virulent than their


and Bovine herpesvirus 1 (BoHV1). In addition these calves were also born from BTV naïve dams (seronegative and RTqPCR negative). They were introduced in an insect secured BSL3 facility 1 week before the beginning of the experiment to allow their acclimatization.

Virus {#Sec4}
-----

BTV1, BTV2, BTV4, BTV9 and BTV16 were all derived from the reference strains of the Onderstepoort Veterinary Institute. These strains underwent further passages at The Pirbright Institute (TPI); passage history is available at the RNAs and Proteins of dsRNA Viruses \[[@CR17]\]. The BTVs were subsequently passaged at Sciensano, Ukkel, Belgium (formerly CODA--CERVA) between two and four times on BHK-21 cells. BTV8 originated from a field sample (BEL2006/01) afterwards passaged 6 times in BHK-21. Each serotype has been tested by RTqPCR specific of the serotypes used in the studyto rule out potential contamination of the inocula.

Experimental design {#Sec5}
-------------------

Five animals were kept as environmental control, and were inoculated with Dulbecco's Modified Eagle Medium (DMEM, Life Technologies, Gent, Belgium). Groups were identified by their vaccination status against BTV8 (V\_ or NV\_, respectively vaccinated and non-vaccinated) followed by the subsequently inoculated BTV serotype (BTV1, BTV2, BTV4, BTV9 or BTV16). For each tested serotype, two groups of three calves each were used. The animals from the first group were vaccinated against BTV8 (BTVPUR AlSap 8, Merial, Lyon, France) following manufacturer instructions, with the second vaccine injection 33 days before challenge. In the other group the animals were not vaccinated.

To be infected, the animals received between 2.5 and 4 mL of inoculum, properly diluted to a normalized titre of 10^6^ TCID~50~/animal. Inoculations were


standard error of the mean. \**P* \< 0.05 between vaccinated and non-vaccinated groups infected with the same serotype. ^\#^*P* \< 0.05 compared to the control group.

BTV RNA detection {#Sec15}
-----------------

No viral RNA was detected in any of the control animals at any time point. Inoculated animals showed different viraemia patterns depending on the inoculated serotype and their vaccination status. The earliest BTV RNA detection in the blood occurred at 1 dpi in NV\_ and V_BTV1 groups. The latest onset of viraemia occurred in one calf of V_BTV2 group at 11 dpi. In calves infected with serotypes 2 and 4 BTV RNA could only be detected inconsistently and RNAemia reached moderate levels when compared to calves infected with BTV1, 9 and 16 (Figure [2](#Fig2){ref-type="fig"}). After the challenge of vaccinated animals, the Log copy number ofVandenbussche et al. \[[@CR19]\] (PN ≤ 66). All these 4 animals had PN that reached values under 35 within 7 dpi.Figure 4**Evolution of serogroup specific antibodies.** The results are presented for each animal as the percentage of negativity (PN) obtained in the competitive ELISA. Data for non-vaccinated (filled circle) and vaccinated (triangle) animals are shown for BTV1 (**A**, **B**), BTV2 (**C**, **D**), BTV4 (**E**, **F**), BTV9 (**G**, **H**) and BTV16 (**I**, **J**). Dotted line represents the cut-off value recommended by the manufacturer and dashed line the one suggested by Vandenbussche et al. \[[@CR18]\]. dpi: day post-infection.

Haematology {#Sec17}
-----------

Monocyte counts increased shortly after infection in all groups but control animals independently of their vaccination status. The increase started between 4 and 11 dpi, peaked at 15 or 18 dpi and then came back


cytotoxic lymphocyte

VERO

:   verda reno

The authors declare that they have no competing interests.

Authors' contributions {#FPar1}
======================

LM, FDP, CS and KdC designed the experimental protocol. CS and KdC allowed the coordination of the project. KdC and IDL provided the inocula. LM and WVC carried out experimental infections, cattle sampling and clinical follows-up. LM and CS performed the necropsy. CT, LM and IDL carried out the laboratory analyses. CS and LM realized the statistical treatment of the data. LM, FDP, CS, KdC and ET contributed to the manuscript drafting. All authors read and approved the final manuscript.

Acknowledgements {#FPar2}
================

The authors are grateful to the members of staff at the Sciensano Machelen Experimental Centre (Belgium).

Availability of data and materials {#FPar3}
==================================

The datasets used and/or analysed during the current study are available from thediscretion. It is properly allowed upon a showing of a misapprehension of the facts or of the law, of any misrepresentation by a person having apparent authority, or where there is a reasonable doubt of guilt or a defense worthy of consideration. People v. McKirdie, 45 Ill.2d 300, 259 N.E.2d 16, People v. Morreale, 412 Ill. 528, 107 N.E.2d 721.
 5, 6 It is argued that the court did not "entertain" the "request" to withdraw the plea. At that time defendant did not have counsel to represent him. The withdrawal of a plea is a critical stage, and should be made and disposed of by orderly proceedings. Defendant has the burden of establishing the basis in fact for the exercise of judicial discretion. People v. Olden, 130 Ill.


Scrap Metal Art - Ordinary plumbing parts—pipes, fittings, and faucets—come together to make robot table lamps full of personality and charm. Turn one on and you suddenly don’t feel so alone in the room. Haha Yosef would love this ;The GMRT image has an rms noise of $\approx$60 $\muup$Jy per beam in the central area (see @2008MNRAS.387.1037G [@2010BASI...38..103G], for details of the data reduction and source extraction). This deep image and the catalogue derived from it are used here.

A deep survey at 1.4 GHz carried out with the WSRT overlaps a large portion of the 10C survey (Fig. \[fig:source\_map\]) in the Lockman Hole [@Guglielmino2012]. The rms noise in the centre of the map is $\approx$11 $\muup$Jy; this map and the associated source catalogue are used in this study.

We also make use of several other catalogues and surveys covering the Lockman Hole region. The Faint Images of the Radio Sky at Twenty cm (FIRST; @1997ApJ...475..479W), NRAO VLA Sky Survey (NVSS; @1998AJ....115.1693C) and Westerbork Northern Sky Survey (WENSS; @1997A+AS..124..259R) cover


the whole area. There are also several deep observations made with the VLA within the Lockman Hole area: @2009AJ....137.4846O at 324 MHz (OMK2009) and @2006MNRAS.371..963B and @2008AJ....136.1889O at 1.4 GHz (BI2006 and OM2008). The locations of these surveys are shown in Fig. \[fig:source\_map\] and are summarised in Table \[tab:surveys\].

Sixteen 10C sources in the Lockman Hole are labelled in the 10C catalogue as part of a ‘group’ (see @2011MNRAS.415.2708D for details) – in this case consisting of eight pairs. Contour maps of these eight pairs were examined by eye, along with images of their counterparts in FIRST and/or GMRT. For three of these pairs, there is evidence of structure connecting the two components, so it was decided to combine the two components into one source (an example of oneGMRT catalogues for the true and shifted distribution of 10C sources. Beyond 15 arcsec the number of true and shifted matches becomes comparable so 15 arcsec is chosen as the match radius.[]{data-label="fig:radiomatches"}](separation.eps){width="8.2cm"}

### Results of the matching {#section:matching-results}

A summary of the matching between the 10C sources and the other radio catalogues is shown in Table \[tab:matching\]. In total, 266 out of the 296 10C sources are detected at at least one other wavelength. Table \[tab:multi-matches\] summarises the number of sources with matches in more than one other catalogue.

[p[2cm]{}ddd]{} Catalogue & & &\
& & &\
(1) & (2) & (3) & (4)\
GMRT & 205 & 291 & 8\
WSRT & 160 & 182 & 10\
FIRST & 196 & 296 & 0\
NVSS & 166 & 296 & 0\
WENSS & 86 & 296 &


for any of the unmatched 10C sources in the WSRT area. The upper limit of flux density was taken to be three times the local noise in the WSRT image. For the 28 sources which were unmatched at 1.4 GHz and outside the WSRT area, an upper limit of 1 mJy was placed on the flux density because this is the FIRST completeness limit and these sources are all within the FIRST survey area but not detected.

### OM2008 and BI2006

The two deep 1.4 GHz surveys made with the VLA (OM2008 and BI2006) have very small synthesised beams ($\approx 1.5$ arcsec) compared to the 10C survey. As images are not available for these surveys, the flux density values from the catalogues were used. OM2008 do account for the fact that somein any of the 1.4-GHz catalogues which are in the WSRT survey area, the upper limit from the WSRT image (as described in Section \[section:WSRT-FIRST\]), is used to calculate a limiting spectral index. For the remaining sources, an upper limit of 1 mJy from the FIRST survey is used.

The second value, $\alpha_{1.4}^{15.7}N$, only uses values from the NVSS catalogue as this has a resolution comparable to the 10C survey. For the 10C sources which do not appear in NVSS, the limit is derived from the NVSS image (see section \[section:NVSS\]). These values of the spectral index contain a larger number of upper limits but provide a useful comparison when considering the effects of resolution.

Possible effects of variability on the spectral indices are discussed in Section \[section:variability\].

Extent of the


to noise. Sources were classified as extended if they had a signal to noise ratio greater than 20 in the GMRT data and values of $R > 1.35$ in at least two of the datasets used, or a value of $R > 2$ in at least one of the datasets. Sources with a signal to noise ratio less than 20 in the GMRT data were classified as extended if the value of $R$ was greater than 2 in any of the datasets. A comparison of two of the $R$ values used is shown in Fig. \[fig:R\]. For most sources the two values are similar and some of the largest variations are for those sources with low signal to noise values, which is expected because the errors in theintegrated flux densities are larger for the fainter sources.

We are confident that all the sources which fulfil these criteria are extended; however, as we have erred on the side of caution, there will be some sources which have not been classified as extended but do in fact have extended emission on the scale investigated here. In particular, sources which only have a value of $R$ from the WSRT catalogue are not classified as extended as the WSRT beam is larger than that of the other catalogues used here. For this reason, those sources which are not classified as extended are placed in the ‘unclassified’ bin. The 36 sources which do not have a counterpart in any of the four catalogues used here are classified as ‘no information’. The


one such model in Section \[section:s3\].

![The spectral index distributions for sources selected at 1.4 GHz from NVSS (sample Q, shown in the top panel) and FIRST (sample P, middle panel) and 10C sources selected at 15.7 GHz (bottom panel). Limiting spectral indices for the unmatched sources are shown in white – note that these are lower limits in the FIRST and NVSS cases, therefore could only move to the right, and upper limits in the 10C case.[]{data-label="fig:alpha-NVSS-FIRST-10C"}](alpha-NVSS-FIRST.eps){width="8.2cm"}

Comparison with the SKADS Simulated Sky {#section:s3}
=======================================

@2008MNRAS.388.1335W [@2010MNRAS.405..447W] produced a semi-empirical simulation of the extragalactic radio continuum sky which contains $\approx320$ million sources. This simulation covers a sky area of $20 \times 20$ $\rm deg^2$ out to a cosmological redshift of $z = 20$ and down to flux density limits of 10 nJy at71 percent of the source population (Table \[tab:s-cubed\]) in agreement with the discussion in Section \[section:counts\]. The second largest source population are FRII sources, while radio quiet AGN, GPS sources and starforming galaxies each make only small contributions to the simulated source population. The $\rm S^3$ sample covers a region of area 400 $\rm deg^2$ while the deep 10C regions from which sample A is drawn cover 1.73 $\rm deg^2$. In order to investigate the possible impact of clustering on these results, five regions of the $\rm S^3$ sample with areas of 1.73 deg$^2$ were selected at random. The fraction of different sources types in each of these five regions was calculated and the range of values this gave is shown in Table \[tab:s-cubed\]. Although the exact percentages


from that of the 10C sample selected at 15.7 GHz, the flat spectrum population present at 15 GHz being poorly represented in the 1.4-GHz samples. This demonstrates the well-known problem with extrapolating from lower frequencies to predict the properties of the high-frequency population.

The 10C sample was compared to a comparable sample selected from the SKADS Simulated Sky constructed by @2008MNRAS.388.1335W. The spectral index distributions of the two samples differ significantly; there are essentially no sources in the simulated sample with $\alpha < 0.3$ while 40 percent of the 10C sample have $\alpha^{15.7}_{0.61} < 0.3$. There is also a larger proportion of sources with flux densities below 1 mJy in the 10C sample than in the simulated sample – 57 percent of the 10C sources have a flux density below 1 mJy comparedswitching speed is the form of the beam. In particular, the highest switching speed is defined by the resonance frequency of the beam, which is a function of the beam geometry. Conventional beams in MEMS switches have essentially a solid rectangular structure. While such a structure is relatively easy to fabricate, is strong, and is suitable for many switching applications, the resonance frequency of the beam is generally too low to perform high-speed switching.


against the fees explaining his reversal. Day sent mailings to voters criticizing Lingamfelter for supporting the fees in the first place, describing them as "abusive driver taxes," a reference to the revenue-generating purpose of the fees.

Immigration

Lingamfelter accused Day of being insincere in his opposition to illegal immigration. Lingamfelter opposes providing state and local governmental services to illegals. Day focuses more on sanctions for employers of illegals, saying that this issue comes down to jobs.

Personal issues

Lingamfelter also pointed out that while Day describes himself as a licensed counselor and avid hunter, Day's counseling license actually has expired, and he has not had a hunting license in the past 15 months. Day responded that he let his counseling license expire in order to devote himself to the campaign and that13th Directorate by Barry Chubin
Atropos by William DeAndrea
The Red President by Martin Gross
The Ceiling of Hell by Warren Murphy
The Trojan Hearse by Richard S. Prather
President Fu Manch by Sax Rohmer
The Big Fix by Roger L. SimonPresidential Crisis
Seven Days in May by Fletcher Knebel and Charles W. Bailey II
Vanished by Fletcher Knebel
A Fine and Dangerous Season by Keith Raffel

The JFK PlotToo many to list, but...
Mongoose, RIP by William F. Buckley
Executive Action by Mark Lane, Donald Freed and Stephen Jaffe
The Tears of Autumn by Charles McCarry

Presidential Families
Deadly Aims by Ron L. Gerard
The President's Daughter by Jack Higgins
The Devil's Bed by William Kent Krueger
The First Lady Murders, edited by Nancy Pickard
Murder and the First Lady (and other novels) By Elliot Roosevelt
Murder in the White House (and other novels) by Margaret Truman
They've


by Steven Wilson

An Anthology
Mr President, Private Eye, edited by Martin H. Greenberg. Different historical presidents in the role of sleuth

Abraham Lincoln Mysteries
Abraham Lincoln: Detective by Allen Appel
A Night of Horrors: A Historical Thriller about the 24 Hours of Lincoln's Assassination by John C. Berry
The Impeachment of Lincoln by Stephen L. Carter
Lincoln's Hand by Joel Fox
The Lincoln Letter by Gretchen Elassani and Phillip Grizzell
Lincoln's Diary by DL Fowler
Abraham Lincoln: Vampire Hunter by Seth Grahame-Smith
The Assassin's Accomplice by Kate Clifford Larson
The Lincoln Letter by William Martin
The Lincoln Secret by John A. McKinsey
The First Assassin by John J. Miller
The Lincoln Conspiracy by Timothy L. O'Brien
The Murder of Willie Lincoln by Burt Solomon
The Cosgrove Report: Being the Private Inquiry of a Pinkerton Detective into the Death of President Lincoln by G.J.A. O'Toole
President– why would a financial titan want to head-up a brand office? He would acquire the White House, not occupy it. And I made his motivation personal rather than political: he had an old score to settle, one that required nothing less than the resources of the Commander in Chief. I also knew that he needed an antagonist, with an old score of his own to settle. Thus was born the central conflict at the heart of Presidents’ Day: one man’s need for revenge, via the White House, and another’s need to stop him.

Now that reality appears to have “trumped” fiction, I’m often asked if current events inspired Presidents’ Day. My answer is always the same: the idea came to me over three decades ago, and I finally


available back in 1974, when dinosaurs ruled the Earth. For almost thirty years, as I’ve lived my life and traveled the country, I kept my ear open to any news about that missing girl. In April 2001, a local detective reopened the case. Using new investigative methods, including DNA technology, the Kansas Bureau of Investigation’s Cold Case Squad tracked the killer down and charged him with first-degree felony murder. Case closed.

In No Rest for the Wicked, DNA is the key to deciphering a genetic family puzzle. When state archaeologists lift the lid on a suspicious steamer trunk buried in Nantucket’s landfill, the contents reactive intense interest in the island’s most notorious cold case crime, the Baby Alice Spenser kidnapping in 1921. As John pursues the Baby Alice investigation,package saq_KE

import (
	"testing"
	"time"

	"github.com/go-playground/locales"
	"github.com/go-playground/locales/currency"
)

func TestLocale(t *testing.T) {

	trans := New()
	expected := "saq_KE"

	if trans.Locale() != expected {
		t.Errorf("Expected '%s' Got '%s'", expected, trans.Locale())
	}
}

func TestPluralsRange(t *testing.T) {

	trans := New()

	tests := []struct {
		expected locales.PluralRule
	}{
	// {
	// 	expected: locales.PluralRuleOther,
	// },
	}

	rules := trans.PluralsRange()
	// expected := 1
	// if len(rules) != expected {
	// 	t.Errorf("Expected '%d' Got '%d'", expected, len(rules))
	// }

	for _, tt := range tests {

		r := locales.PluralRuleUnknown

		for i := 0; i < len(rules); i++ {
			if rules[i] == tt.expected {
				r = rules[i]
				break
			}
		}
		if r == locales.PluralRuleUnknown {
			t.Errorf("Expected '%s' Got '%s'", tt.expected, r)
		}
	}
}

func TestPluralsOrdinal(t *testing.T) {

	trans := New()

	tests := []struct {
		expected locales.PluralRule
	}{
	// {
	// 	expected: locales.PluralRuleOne,
	// },
	// {
	// 	expected: locales.PluralRuleTwo,
	// },
	// {
	// 	expected: locales.PluralRuleFew,
	// },
	// {
	// 	expected: locales.PluralRuleOther,
	// },
	}

	rules := trans.PluralsOrdinal()
	// expected := 4
	// if len(rules) != expected {
	// 	t.Errorf("Expected '%d' Got '%d'", expected, len(rules))
	// }

	for _, tt := range tests {

		r


:= locales.PluralRuleUnknown

		for i := 0; i < len(rules); i++ {
			if rules[i] == tt.expected {
				r = rules[i]
				break
			}
		}
		if r == locales.PluralRuleUnknown {
			t.Errorf("Expected '%s' Got '%s'", tt.expected, r)
		}
	}
}

func TestPluralsCardinal(t *testing.T) {

	trans := New()

	tests := []struct {
		expected locales.PluralRule
	}{
	// {
	// 	expected: locales.PluralRuleOne,
	// },
	// {
	// 	expected: locales.PluralRuleOther,
	// },
	}

	rules := trans.PluralsCardinal()
	// expected := 2
	// if len(rules) != expected {
	// 	t.Errorf("Expected '%d' Got '%d'", expected, len(rules))
	// }

	for _, tt := range tests {

		r := locales.PluralRuleUnknown

		for i := 0; i < len(rules); i++ {
			if rules[i] == tt.expected {
				r = rules[i]
				break
			}
		}
		if r == locales.PluralRuleUnknown {
			t.Errorf("Expected '%s' Got '%s'", tt.expected, r)
		}
	}
}

func TestRangePlurals(t *testing.T) {

	trans := New()

	tests := []struct {
		num1     float64
		v1       uint64
		num2     float64
		v2       uint64
		expected locales.PluralRule
	}{
	// {
	// 	num1:      -0,
	// 	v:        2,
	// 	expected: "0.00",
	// },
	// {
	// 	num:      -0,
	// 	v:        2,
	// 	expected: "0.00",
	// },
	}

	trans := New()

	for _, tt := range tests {
		s := trans.FmtNumber(tt.num, tt.v)
		if s != tt.expected {
			t.Errorf("Expected '%s' Got '%s'", tt.expected, s)
		}
	}
}

func TestFmtCurrency(t *testing.T) {

	tests := []struct {
		num      float64
		v        uint64
		currency currency.Type
		expected string
	}{
	// {
	// 	num:      1123456.5643,
	// 	v:        2,
	// 	currency: currency.USD,
	// 	expected: "$1,123,456.56",
	// },
	// {
	// 	num:      1123456.5643,
	// 	v:        1,
	// 	currency: currency.USD,
	// 	expected: "$1,123,456.60",
	// },
	// {
	// 	num:


Texans @ Bengals

Fresh off a season opener which featured an electric rookie breakout and tons of scoring, the first “true” Thursday night game gets back to form this week, offering a Bengals-Texans matchup that should be nothing short of unwatchable. With Andy Dalton coming off a five turnover performance and the Texans still actually debating sending Tom Savage back out there, NBC ought to provide complementary ice picks so their viewers can mercifully gouge their own eyes out before halftime. With a murky Cincinnati backfield situation, awful QB play, and lockdown defenses, there simply isn’t a lot to get excited for in this matchup. I bet AJ Green gets uncorked in the first half, but outside of that, there aren’t many safe plays in this awful affair.

Story toinvolved with this game being tighter than the previous contest. While it may sound like I’m a bit down on Cam, that’s not the case this week – I see him as a good bet for 250 yards and two touchdowns.

Hope For The Best: If Kelvin Benjamin is your WR1 somehow, well, I feel sorry for you. That said, there’s no reason to sit him down just yet. He had a chance at a deep touchdown last week before a Niners defender pulled off the top highlight of week 1, intercepting the ball with one hand. I love Jonathan Stewart this year, but his upside is definitely capped. He’s a fine RB2/flex on a weekly basis. Tyrod Taylor will have a tough assignment on the road, but you


very useful when a new tester comes.

3. You can see the whole view of your design which isn’t covered in requirements.

4. The workflow is clear when you see the test cases.

The main benefit of writing test cases is in the activity of writing them.

Now we know, why we will write test cases. Let’s dive into the code. I recommend Mocha as a testing engine. It runs in a Node Environment.

It’s very simple to install, run the command below in the project

npm install --save-dev mocha

then,

to use it with Babel

npm install --save dev babel-register

and configure it to use ES6 features in .babelrc:

{

"presets": ["es2017"]

}

Then, add this to scripts in your package.json:

{

...

"scripts": {

...

"test": "mocha --compilers js:babel-register --recursive",

"test:watch": "npm test -- --watch",

},

...

}

Run ‘npm test’ to run it once, or ‘npm run test:watch’ to{ return new Projectss(item); });
                self.Projects(MappedProjects);
            },
            error: function (xhr, status) {
                alert(status + " - " + xhr.responseText);
            }

        });
    };

    $(document).ready(function () {
        var VM = new ProjectModel();
        ko.applyBindings(VM);
    })

</script>

This is where I