If you thought George and Jeb were dodgy, check out the twin president–prime minister combo in Poland. I am not sure how happy I would be about this if I were a SolidarnoÅ›Ä‡ member (and I would likely have been one, had I been Polish at that juncture). (But then, Bulgaria had an ex-king for a prime minister until last year.)

4 Comments

John Waite investigates the legacy of the 1960s building boom for those who did the spadework. Thousands of Irish labourers came here hoping to escape grinding poverty but ended up destitute in old age. Many are homeless and have no right to a state pension as they worked for cash in a system known as “the lump”. John asks who benefitted from the system and as theJune 4th was the day of the historic elections in Poland that elected Solidarity as the new government. They hadn’t had elections there in decades. And this was the event that really set off the domino — whatâ€™s now referred to as the domino effect in Eastern Bloc countries — and ultimately resulting in the breaking apart of the Soviet Union. But itâ€™s worth remembering what it actually looked like in June of 1989. In Poland, people didnâ€™t think that history was over, because they had just elected Solidarity as their government. They thought that history was just beginning and that they were finally going to be able to implement what the movement, which was a labor movement, had always seen as the third way, the third way


by 35% (p = 0.0114) and expression of serum amyloid protein - the main protein induced upon LPS challenge - by 44% (p < 0.0001). On contrary, in presence of synovial membrane, the protective effects of S-(+)-ibuprofen on cartilage damages were significantly diminished. At 1mM, S-(+)-ibuprofen reduced the cell lysis during culture of cartilage and joint capsule either in mono- or in co-culture. This study performed on sheep explants shows that 1 mM S-(+)-ibuprofen inhibited cartilage degradation via a mechanism independent of cyclooxygenase inhibition. Reduction of prostaglandins synthesis at 50 µM in all treatment groups and reduction of cartilage degradation observed at 1 mM suggest that S-(+)-ibuprofen could be considered as a promising drug candidate for the loading of intra-articular DDS.various social media accounts and anything that might send me alerts, subscriptions, etc) and only the important one is sent to my phone. Any non-essential or time sensitive email I receive is tagged and saved for later—usually on long flights when I have nothing to do (a great time to respond to reader and fan mail).

However, I also find that phone calls are the biggest interruption to my writing and work so I have always been a deliberately heavy user of email. I’d prefer you email me instead of call so I can deal with it on my own time. I don’t handle any business over text messages, preferring that people email me. The result is that I have become increasingly dependent on email for my business life—so


John Delaney John Hickenlooper Julián Castro Kamala Harris Kirsten Gillibrand Marianne Williamson Michael Bennet Mitch Landrieu Pete Buttigieg Seth Moulton Stacey Abrams Steve Bullock Tim Ryan Tom Steyer Tulsi Gabbard Wayne Messam Someone else Undecided

OPTIONAL: I support holding Republicans accountable for their health care votes in 2018 and want updates from the Health Care Voter campaign.

OPTIONAL: Can you chip in $3 to our work electing a progressive president in 2020 and making sure they have a progressive Congress that will enact their agenda? Yes, I'll donate $3. Yes, but I'll donate more. How much? $10 $20 $50 $100 $250 $1000 I would donate monthly.

Please text me progressive action alerts!

By entering your cell phone number, you are consenting to receive periodic text message alerts from PCCC about progressive actions.Single-agent methotrexate chemotherapy for the treatment of nonmetastatic gestational trophoblastic tumors.
Our purpose was to evaluate the efficacy and toxicity of single-agent methotrexate chemotherapy and to identify factors associated with chemotherapy resistance in patients with nonmetastatic gestational trophoblastic tumors. A total of 337 patients with nonmetastatic gestational trophoblastic tumors (choriocarcinoma and invasive mole) received treatment at the Brewer Trophoblastic Disease Center of Northwestern University Medical School from 1962 through 1990. Of the 337 patients, 253 (75.0%) were treated initially with single-agent methotrexate 0.4 mg/kg intravenously daily for 5 days per treatment course repeated every 14 days. All 337 patients with nonmetastatic gestational trophoblastic tumors were cured. Of the 253 patients initially treated with methotrexate, resistance developed in 27 (10.7%), 22 (8.7%) required a second agent (actinomycin D), 3 (1.2%)


local bike rides each week through a club called the Lansing Bike Party.

Jeff Potter, a Williamston resident, says he's "wildly enthusiastic" about plans for an east side connector, noting that it's difficult for members of his club to avoid busy streets when biking from East Lansing to Lansing.

"There seems to be a gulf between the two cities," Potter said. "(U.S. Route) 127 creates a real barrier, socially and physically."

Tim Potter, also an advocate for bike-friendly transportation through the Tri-County Bicycle Association, bikes each day from Okemos to his job at Michigan State University's bike shop in East Lansing.

Many amateur cyclists, he said, only feel comfortable riding to work if there is dedicated infrastructure such as bike lanes that are set apart by physical barriers.

"There's a lot of peoplevarious perspectives including planning, control, and learning. In real-world grasping, the full 3D shape of the object is hard to perceive and certain grippers are difficult to replicate with a physical model for study and grasp planning.
Several approaches have been successful in solving the problem of robotic grasping. For example, if the kinematics of the EOAT are known and a two-dimensional (2D) or three-dimensional (3D) model of the object is available, methods that consider form closure and force closure can be used to plan a grasp. Heuristic rules have been used to generate and evaluate grasps for three-fingered hands by assuming that the objects are made of basic shapes such as spheres, boxes, cones and cylinders, each with pre-computed grasp primitives. Other methods focus on grasping 2D planar


objects using edges and contours to determine form closure and force closure. Further methods considered grasping planar objects by classifying them into a few basic shapes, and then used pre-scripted rules based on fuzzy logic to predict the grasp. Yet other methods used support vector machines to estimate the quality of a grasp given a number of features based on spin images. Closed loop feedback has also been used to perform grasps, both with visual feedback and tactile feedback. Most of these methods however assume a physical model of the gripper and often a very detailed physical model is required. In instances when the object geometry is known as well as the gripper geometry, control and planning algorithms are designed from the known geometric information for successful graspingconform to vesting rules

Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

Explanation:The Employee Retirement Income Security Act of 1974 (ERISA) is a federal law that sets minimum standards for pension plans in private industry. For example, if your employer maintains a pension plan, ERISA specifies when you must be allowed to become a participant, how long you have to work before you have a non-forfeitable interest in your pension, how long you can be away from your job before it might affect your benefits, and whether your spouse has


them here and get a little more foundation under them before they get out.”

Parton said many who come through Pathways’ doors suffer from some kind of an addiction problem.

“It’s probably 90 percent for the folks who come through our doors either are having or have had some kind of substance abuse issue,” he said.

Although Parton acknowledges that Pathways can’t meet the needs for those going through withdrawals who have serious medical or rehabilitation needs, the facility does require recovering addicts to attend recovery meetings and seek adequate treatment.

He added that Pathways is considered a 100 percent no-tolerance facility, but the group has had to change its policy slightly to truly reach those in need.

The shelter used to not admit people who tested positive for drugs or alcohol, butofficers. Courts. Alteration.

Part 12: Repeals and Date of Commencement
 Sections 141 and 142.
Commencement. Revocations.

Schedules
 1: Definition of Belize.
 2: Alteration of Constitution (Section 69).
 3: Oath of Allegiance and Office
 4: Revocations.

Creative history
Belize in the late 1970s was engaged in a territorial dispute with Guatemala. It became increasingly clear that Belize had more international support and a stronger case, hence the talk of independence which had existed since self-government in 1963. Repeated demands by Guatemala and the United Kingdom that Belize cede territory were rejected by Premier George Cadle Price and the ruling People's United Party. By contrast, the newly formed Opposition United Democratic Party wanted the claim settled before proceeding to Independence. In the general elections of 1979, the PUP won and the seeds


/*
 * Password Management Servlets (PWM)
 * http://www.pwm-project.org
 *
 * Copyright (c) 2006-2009 Novell, Inc.
 * Copyright (c) 2009-2020 The PWM Project
 *
 * Licensed under the Apache License, Version 2.0 (the "License");
 * you may not use this file except in compliance with the License.
 * You may obtain a copy of the License at
 *
 *     http://www.apache.org/licenses/LICENSE-2.0
 *
 * Unless required by applicable law or agreed to in writing, software
 * distributed under the License is distributed on an "AS IS" BASIS,
 * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 * See the License for the specific language governing permissions and
 * limitations under the License.
 */

package password.pwm.config.value.data;

import lombok.Value;
import password.pwm.util.PasswordData;

import java.io.Serializable;
import java.util.List;

@Value
public class NamedSecretData implements Serializable
{
  KOTOR GAMES 1 N 2

hey guys have u guys ever played Knights of the old republic 1 or 2 its a fun game to me in eny way. eavn u all ready played the game a thousand times and its boring its good to put Mods and cheats lol.

Hey blue ninja im srry for dubble posting i new that someone will get me on that its jest that........i thout it would be weird that i would say i love u to graanu and he will man a topic about it lol... btw i know this is not the part of the topic but how do you put your screenshots on your posts???


namely creationism and its modern form, intelligent design (ID), into schools and into the science classroom specifically. This paper looks at recent events in the UK, paying particular attention to NI, and presenting data regarding the possible impact of such attempts on pre-service science teachers studying in NI over the past 2 years. In 2006, Truth in Science (TiS), a UKbased group set-up in 2005, sent resource packs promoting ID to the science department of all UK secondary schools. The resource pack includes a DVD resource featuring members of the Discovery Institute1, information regarding Evo Edu Outreach (2009) 2:372–385 DOI 10.1007/s12052-009-0141-4 1 A Seattle-based group, which has been described as an intelligent design think-tank (Brumfiel 2005; Holden 2006), but more generally describes itself as a public-policy organization, withstudents in 2008 comprised a number of demographic items (gender, age, religion, course of study), three open-ended items on the nature of science (NoS) and evolution, and an evolution attitude scale, which incorporated items from existing scales (Rutledge and Warden 1999; Ingram and Nelson 2006). This paper intends to provide a snapshot of the attitudes of prospective science teachers in NI toward evolution and creationism and survey responses to challenges presented concerning evolution. Data relating to religious variables were collected in the questionnaire of 112 prospective science teachers, but not at the time of focus groups. Further research is under way, examining the effects of variables such as religious affiliation, selfidentified worldview, and religious upbringing, and it is the intention of the authors to build on the attitude


acceptance of evolution and prepared to challenge what they perceived as an attempt to advance creationism: What you have to think about that video is that I think they would listen to that and go "oh Darwinism is just rubbish and why even bother to teach me that?"... Like you say they just hear something and accept it as fact. Well I can't accept it as fact that this "proves" creationism, when it doesn't even prove that. [Suze, gp1] "Theory Not fact" and "Teach the Controversy" The majority of participants in discussion did not indicate strong leanings to either creationism or evolution and were more accurately characterized by a "middle-ground" position. Typically, the language used in articulating their opinions indicated either a form of relativism, treating all theoriessupport it has within the Evo Edu Outreach (2009) 2:372–385 383 community of scientists. Only by identifying attitudes toward the relevant issues, including any misconceptions concerning the nature of science and evolution generally, can it be hoped that the attempts to undermine evolution education can be defended against by those in a key position to do so-classroom science teachers. The implications of these findings raise a number of important questions and general points: – The DVD resource persuaded many new teachers- how should science educators respond? – These new teachers took an unsolicited resource at face value-the same DVD had been sent to all UK secondary schools. How can new teachers be helped to make critical judgments about what resources are suitable to support the curriculum? – The


secondary pupils attending catholic and Protestant schools in Northern Ireland. Public Underst Sci. 1999;8:93–103. doi:10.1088/0963-6625/8/2/302. Francis LJ, Greer JE. Shaping adolescents' attitudes towards science and religion in Northern Ireland: the role of scientism, creationism and denominational schools. Res Sci Technol Educ. 2001;19 (1):39–53. Gregory TR. Evolution as fact, theory, and path. Evo Edu Outreach. 2008;1(1):46–52. Henry LA. Tussle of Biblical proportions over creationism in Ulster classrooms. 2007. http://www.belfasttelegraph.co.uk/news/education/ tussle-of-biblical-proportions-over-creationism-in-ulster-classrooms13479246.html. Accessed 30 Sept 2008. Hofer BK, Lam CF, Hopkinson A. Understanding evolutionary theory: issues of epistemology, science education, and conceptual change. 2006. Text of paper presented at the annual meeting of the American Educational Research Association. April Holden C. Ohio school board boots out ID. Science. 2006;311 (24):1083. Ingram EL, Nelson CE. Relationship between achievement and students' acceptance ofMcGill J Edu. 2007;42(2):307–3126. Scott EC, Branch G. Evolution: what's wrong with "teaching the controversy". Trends Eco Evo. 2003;18(10):499–502. Scott EC, Branch G. Not in our classrooms: why intelligent design is wrong for our schools. 1st ed. Boston: Beacon; 2006. Shanks N. God, the devil, and Darwin: a critique of intelligent design theory. Oxford: Oxford University Press; 2004. Shermer M. Why Darwin matters: the case against intelligent design. 1st ed. New York: Times Books; 2006. Sinatra GM, Southerland SA, McConaughy F, Demastes JW. Intentions and beliefs in students' understanding and acceptance of biological evolution. J Res Sci Teach. 2003;40(5):510–28. Sober E. What is wrong with intelligent design? Q Rev Biol. 2007;82 (1):3–8. Spencer N, Alexander D. Rescuing Darwin: God and evolution in Britain today. 2009. http://campaigndirector.moodia.com/Client/ Theos/Files/RescuingDarwin.pdf. Accessed


enquiry form below and one of our friendly staff will get in touch with you to discuss your every need! If there is anything you are unsure about you can always call us on 0208 547 2857 where we'll be happy to help.revealed that z-ligustilide and n-butylidenephthalide are major components accounting for 39% and 5% in the AE-AS, respectively (Fig. [1A](#Fig1){ref-type="fig"}). Hypoxia-induced ROS formation is known to increase HIF-1α protein stability^[@CR15]^. Exposure of human bladder cancer (T24) cells to hypoxia for 3 h markedly increased O~2~ ^**−**^ and H~2~O~2~ formation, which was dose-dependently inhibited by AE-AS (Fig. [1B](#Fig1){ref-type="fig"}). Additionally, elevated HIF-1α mRNA expression (Fig. [1C](#Fig1){ref-type="fig"}), HIF-1α transcriptional activity (Fig. [1D](#Fig1){ref-type="fig"}), and nuclear HIF-1α protein level (Fig. [2A](#Fig2){ref-type="fig"}) in hypoxic T24 cells were significantly inhibited by AE-AS. Similarly, a marked increase of nuclear HIF-1α protein level in T24 cells caused by deferoxamine (DFO), an iron chelating agent acting as a hypoxia mimetic agent, was also inhibited by AE-AS (Fig. [2B](#Fig2){ref-type="fig"}).Figure 1AE-AS inhibited ROS formation, HIF-1α mRNA expression and activation in hypoxic T24 cells. The analysis of chemical components


of PHD-mediated HIF-1α hydroxylation and degradation. To further examine whether AE-AS affects HIF-1α protein synthesis, T24 cells were pretreated with MG132 for 30 min to prevent HIF-1α degradation, followed by hypoxia for 8 h in the presence or absence of AE-AS. As shown in Fig. [3C](#Fig3){ref-type="fig"}, hypoxia-induced newly synthesized HIF-1α protein was dose-dependently inhibited by AE-AS. Recent study has demonstrated that the WD repeat and SOCS box-containing protein-1 (WSB-1), a pVHL E3 ligase, can promote pVHL ubiquitination and proteasomal degradation in various tumors via WSB-1-pVHL interaction^[@CR15]^. To further investigate whether WSB-1 regulates the HIF-1α/VEGF cascade in bladder cancer, the short interfering RNA (siRNA) WSB-1 was used. Consistently, hypoxia-induced nuclear HIF-1α level and VEGF synthesis in T24 cells was greatly reduced by si-WSB-1 (Fig. [3D](#Fig3){ref-type="fig"}), indicating that WSB-1 also stimulates the HIF-1α/VEGF cascadeby VEGF (100 ng) in Matrigel plugs was photographed and stained with H&E (200×). The infiltrating microvessels with intact RBC were quantified by manual counting using high power fields (200×) \*\**P* \< 0.01, \*\*\**P* \< 0.001 versus VEGF-treated alone group.

AE-AS inhibits tumor growth and HIF-1α/VEGF/VEGFR pathway *in vivo* {#Sec7}
-------------------------------------------------------------------

In a xenograft mouse cancer model, the tumor size and weight of AE-AS-treated mice were much lower than that in untreated cancer mice (Control group), and AE-AS treatment did not affect the body weight of mice (Fig. [6A](#Fig6){ref-type="fig"}). As expected, the increased protein expression of HIF-1α, VEGF, pVEGFR2, and CD31 (PECAM-1), a specific endothelial cell marker, in tumor tissues determined by immunohistochemical staining or Western blotting assay was also greatly suppressed after AE-AS treatment (Fig. [6B](#Fig6){ref-type="fig"}).Figure 6AE-AS reduced tumor angiogenesis and growth. The mice were injected


for promoting HIF-1α degradation, and suppressing the transcriptional activity of HIF-1α by preventing PHD and FIH inactivation.

It has been reported that loss or mutation of pVHL remarkably enhances HIF-1α protein accumulation, and tumor angiogenesis, proliferation and metastasis^[@CR22]--[@CR24]^, supportting that preventing pVHL protein loss is capable of attenuating tumorigenesis. Recent study has identified that WSB-1 reduces the pVHL protein amount by stimuating pVHL ubiquitination and proteasomal degradation, thereby stabilizing HIF-1α^[@CR15]^. Importantly, WSB-1 is a target gene of HIF-1α^[@CR24]^, suggesting a positively feedback loop existing in WSB-1 and HIF-1α via regulation of pVHL turnover. Our data showed that knocking down WSB-1 with si-WSB-1 markedly reversed the elevation of nuclear HIF-1α level and VEGF synthesis in hypoxic T24 cells, indicating that WSB-1 plays a crucial role in the activation of HIF-1α/VEGF(Applied Biosystems, Carlsbad, CA, USA) were incubated in 10 μl at 50 °C for 10 min and 95 °Cfor 5 min, followed by 45 cycles of 95 °C for 10 s, and 72 °C for 30 s. Each reaction was run in duplicate and the threshold (*C* ~T~) values for each mRNA were subtracted from that of β-actin mRNA, averaged, and converted from log-linear to linear term.

The primer sequences used in the PCRs were as follows:

HIF-1α (forward) 5′-TGAGGAAATGAGAGAAATGCTTACA-3′

HIF-1α (reverse) 5′-ACACTGAGGTTGGTTACTGTTGGT-3′

VEGF (forward) 5′-CCAGCACATAGGAGAGATGAGCTT-3′

VEGF (reverse) 5′-TCTTTCTTTGGTCTGCATTCACAT-3′

β-actin (forward) 5′-TCTGGCACCACACCTTCTACAA-3′

β-actin (reverse) 5′-GTACATGGCTGGGGTGTTGAAG-3′

HIF-1α activity and VEGF measurement {#Sec16}
------------------------------------

The HIF-1α activity was determined by HIF-1α Combo Transcription Factor Assay Kit according to the manufacturer's instructions (Cayman, Ann Arbor, MI, USA). The amounts of VEGF were measured by using VEGF enzyme-linked immunosorbent assay (ELISA) kit (R&D Systems, MN, USA).

Western blotting assay {#Sec17}
----------------------

The nuclear and


and corresponding roles, so ideally the method would not demand specifying the column names. One solution which I came up with is below, but I don't think it is the most elegant way to go. And I still would need to deal with some data frames containing participant.3, role.3 etc.
good_df2 <- rbind(bad_df %>% select(id, participant.1, role.1) %>%
                    rename(participant = participant.1, role = role.1),
                 bad_df %>% select(id, participant.2, role.2) %>%
                    rename(participant = participant.2,    sep='var.stubs')[, 2:= NULL]
#      id participant     role
#1: id001        Jana   writer
#2: id001        Niko observer
#3: id002      Marina   writer
#4: id002       Micha observer
#5: id003     Vasilei  speaker
#6: id003        Niko observer

Or using dplyr/tidyr
library(dplyr)
library(tidyr)
gather(bad_df, Var, Val, -id) %>%
        separate(Var, into=c('Var1', 'Var2')) %>%
        spread(Var1, Val) %>%
        select(-Var2)
#    id participant     role
#1 id001


     Jana   writer
#2 id001        Niko observer
#3 id002      Marina   writer
#4 id002       Micha observer
#5 id003     Vasilei  speaker
#6 id003        Niko observer

A:

I'd go this way in base R:
 #find the participant columns
 partCol<-grep("part",colnames(bad_df))
 #... and the role columns
 roleCol<-grep("role",colnames(bad_df))
 data.frame(id=rep(bad_df$id,each=length(partCol)),
            partecipant=as.vector(as.matrix(t(bad_df[,partCol]))),
            role=as.vector(as.matrix(t(bad_df[,roleCol]))))

GCroke.
Monday
BTS – Starlin Castro (Was 4 for 5 yesterday v. Braves)
HR – Hamilton v. Harden who was with Cubs a few years ago and can be great or terrible. Gives up the long ball alot.
Game in TX and Hamilton is hot – like my chances here.
Survivor – RSox
Wednesday Aug 25 – Rockies in a day game and Tulowitzki has hit in all the day games he has played in this year.

“Looks like Dave is saying the leader, George, has more tie breaker hits than GCroke.”
Don’t know, depends on how you read between the lines. One may read it as: “Though Dick lost the tiebreaker, this is what a good sport the guy is…” Though I doubt Dave was hinting one way or the other & may be prevented


We believe there is only one true and living God. He is immutable, indefatigable and infinite. He is an intelligent Spirit, reality and creator of all. He is God the Father, God the Son, and God the Holy Spirit.

Rev. Fred Jeff Smith

Rev. Fred Jeff Smith was recently elected the new pastor of the church. He's following his father, Rev. Charles T. Smith, who pastored the church for 50 years and his grandfather, Rev. Dudley T. Smith.

Early Learnig Center

An Early Learning Center where we offer classes for children from 3 months through 1st grade. We have an enrollment of 150 students. Its called the Shiloh Early Learning Academy and 23 full time and 3 part time employees.

Rev. Charles T. Smith

"This, then, is how you should pray: " 'Our Father

                scope = new ManagementScope(@"\\<IP address/machine name>\root\CIMV2", options);

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                using (ManagementObjectCollection queryCollection


in New Iberia Broadcasting Co., supra, Note 4, and in the present case, the Commission abandoned that approach and held the power increase policy to be paramount without a hearing and without discussion of the facts in the particular case.

II.  This Case

5
Radio Stations WGNY of Newburgh, New York, and WKIP of Poughkeepsie, New York, about 15 miles away, intervenor here, are commonly owned.  An overlap of coverage had been waived at the time they came under common ownership.  Immediately prior to the application here in suit the overlap amounted to 210 square miles containing 40,181 persons. /11/ In 1961 WKIP, a Class IV station then operating at a power of 250 watts from a rooftop antenna, made application to increase transmitter power to 1,000 wattsper cent is due to the antenna change, and only 20 per cent to the transmitter power increase.  Antenna changes of this magnitude under Commission regulations would constitute a 'substantial change' in facilities, requiring publication of the application to afford opportunity to interested parties to file objections.15  Petitioner filed objections based on the overlap rule which prima facie would require rejection of the application.  But the Commission granted the application without a hearing in an opinion which never mentions the antenna change and cites no authority which is pertinent to antenna change applications.

9
The Commission in brief attempts to justify this sub silentio approval of the antenna change on the ground that 'the authority for Class IV stations to use power of 1 kilowatt daytime is


chose amohg them.  Its brief contains a composite statement of facts selected from the pleadings which it asserts support the grant of the application.

16
Facts militating against the grant are dismissed as 'not important.'  Obviously, counsel cannot perform the fact finding function for the Commission.  Nor can we assume that the facts submitted by its counsel are the facts on which the Commission acted.24

17
Turning to the second criterion, the issue is whether the Commission could determine, without the aid of adversary presentation, that the grant of this application would serve the public interest, convenience and necessity.  The Commission here contends that it could, arguing (1) that the overlap policy is relatively unimportant, and (2) that the Class IV power increase policy is more strongly inextent of the overlap.  Other facts, such as the relationship of the two cities, remained in dispute

24
 'The Commission's action cannot be upheld merely because findings might have been made and considerations disclosed which would justify its order as an appropriate safeguard for the interests protected by the Act.  There must be such a responsible finding.'  Securities & Exchange Comm. v. Chenery Corp., 318 U.S. 80, 94, 63 S.Ct. 454, 462, 87 L.Ed. 626 (1943)

25
 Note 1, supra

26
 Kansas Broadcasters, Inc., 23 R.R. 1112a (1963); Sheffield Broadcasting Co., 21 R.R. 514j (1962)

27
 Paul A. Brandt, supra, Note 2

28
 See Note 10, supra

29
 27 F.R. 6846 (1962)

30
 The importance of this policy has also been emphasized by the courts.  See Sunbeam Television Corp. v. Federal


peripheral neuropathy pain medicine ulnar nerve neuropathy therapy

It helps to manage the symptoms which are associated with diabetic neuropathy like fatigue, pain in calf muscles, weight loss, loss of sensation in feet, sharp pains around shoulders and neck region.
The Hopkins study is different from those done in the past because it showed deterioration over the entire length of sensory nerve fibers and not just at the ends, which suggests the damage is not peripheral neuropathy pain medicine localized.
A major challenge, however, is the lack of specific treatment to slow the progression or prevent the development of CAN.
The important role of supersensitive structures after neuropathy or denervation was previously neglected.
During chemotherapy treatment it is important to use therapies that do not interfere with the chemotherapy drugs.
This unit will givemore rural areas, reaching the residential community of Pottersville.

After crossing the Lamington River, CR 512 enters Bedminster Township in Somerset County and becomes Pottersville Road, heading out of Pottersville and back into areas of farms and woods with a few residences. The road enters Peapack-Gladstone and immediately crosses US 206 in woodland before entering residential areas. CR 512 intersects CR 671 and turns south onto Main Street, passing the Gladstone station, which serves as the western terminus of New Jersey Transit's Gladstone Branch. The road runs to the east of the railroad tracks before turning east and then south at a junction with CR 647. The route continues through a mix of homes and businesses, intersecting CR 661. CR 512 enters a mix of fields and residences before


that should work in Debian or Ubuntu and a PPA that should work in Ubuntu. Arch has its own rEFInd package.) This should then get you booting -- but again, you may need to tweak things a bit.
Run the Boot Repair utility from a boot of an Ubuntu emergency disk, booted in EFI mode. This should install the EFI version of GRUB 2 to your computer, which should pick up your distributions and make them bootable. Unfortunately, GRUB 2 can be a bit iffy with multiple Linux distributions, especially exotic ones -- the OS-detection scripts sometimes aren't optimized or up-to-date for distributions other than the one for which the package was made. Thus, if you use Boot Repair (which is basically an Ubuntu tool), it's quite possible that        @ is arg >= maxlong?
    cmp     r0, #0                      @ nonzero == yes
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    mvnne   r1, #0x80000000
    ldmnefd sp!, {r4, pc}

    mov     r0, r4                      @


to be more about sharing reflection and potentially starts the voyage into a paradigm shift in my coaching. However, I hope you can see where I am coming from and that you may have similar thoughts and conversations from your own coaching.

When I look back over the years I have been coaching, having started at 16 and now just turned 37, I can reflect and say that I think I have honestly only ‘coached’ for the last five years. Before that, I’m not convinced what I was doing was coaching, maybe putting on football practices for kids, but I certainly didn’t KNOW what I was doing or WHY I was doing it. Having spent time considering the journey and influencers on my coaching I can now start tonew InvalidOperationException(string.Format("Service {0} is required.", typeof(T).Name));
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        }

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        {
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        }
    }
}


Iraq, the US will retaliate on a tactical level, and they will strike against military targets. The second part of this is: Bush has made the decision to launch a strategic attack against Iranian nuclear facilities, although not before next year. He has been lining up some Sunni countries for tacit support for his actions."

US and British officials have complained to Iran about the use by Shia militias in Iraq of what they say are Iranian-made weapons. The main concern is the proliferation of roadside bombs that fire a bolt of molten metal through any thickness of armour, which the officials say must have been made in Iran.

A US military spokesman in Baghdad, Major General Kevin Bergner, raised the stakes when he said the 240mm rocket that hitthe US military headquarters outside Baghdad this week, killing an American soldier and wounding 11, had been supplied to Shia militants by Iran.

Gen Bergner used to work in the White House, where he was aligned with administration hawks, and his dispatch to Baghdad was seen by some as a move to increase pressure on Iran.

"There are an awful lot of lower level officers who are very angry about the deaths from explosively formed projectiles said to come from Iran. There is a certain amount of military pressure to do something about this," said Patrick Clawson, the deputy director for research at the Washington Institute for Near East Policy. "That said, it is very difficult for us to do anything without much better evidence. In that respect, border control


in the delayed formation of barrels observed in nutritionally restricted rats. It was found that the rates of development and the segregation of thalamo-cortical fibers were normal in nutritionally restricted rats. SERT, but not 5-HT(1B) immunoreactivity, was decreased in the primary somatosensory cortex during barrel specification. The availability of both proteins in nutritionally restricted rats was lower than that observed in their well fed counterparts at later developmental times. It is concluded that the delayed formation of barrels observed in nutritionally restricted rats is due to a retarded reorientation of dendritic arbors of cortical neurons. This might happen as a secondary effect of decreasing the availability of SERT and/or increasing the availability of 5-HT(1B) receptor early in postnatal life.aesthetic diversity had further Westernized the world. America’s sacred idea of individualism had been diminished through the nation’s own technology. Selfies, Tom and I realized, are part of an emergent phenomenon that we dubbed the “Autopanopticon.”

Thus far on my road trip and into my assignment, the only absolute I’d reached was that we’ll never have direct access to reality. We don't exist outside of ourselves. We’re born having no knowledge about consciousness; it's something we become aware of through science, images, language, interaction and experience. Most of it is determined through culture and geography. Reality is not at one with the mind.

The Autopanopticon is the only reliable tool we have for acting from a unified perspective. It not only posits that we are aware of the world around


Spiritual Life

Following is the second in a three-part series on Young’s experience as a Christian pastor at Burning Man, the annual art event and temporary community based on radical self-expression and self-reliance in the Black Rock Desert of Nevada.

Burning Man, the weeklong festival in the northern Nevada desert, is one of the largest religious rituals in the western world.

We danced, created and destroyed things together. We talked, cried, yelled and sat in silence. We came to the holy desert from wildly different places, but even in our ecstasy and despair, mostly we were one – like the future city that John of Patmos calls the New Jerusalem.

Burners greet each other with hospitality, saying, “Welcome home!” For me, this means, “Express your wonderful uniqueness, because we act as athis series are named using the pattern "NL<number>".
Further, numerical expressions are not formed merely by arranging numerals and symbols, and there are rules that govern the interpretation of the contents of expressions. In a fraction, for example, normally two numbers are juxtaposed with an intervening "/" symbol, since ordinarily not more than two strings of numerals are used with an intervening "/", and in addition, in a fraction a number before or after a "/" usually does not begin with a "0". However, in a date expression that employs the same "/" symbol, three numbers may be included, as in "Nov. 05, 1997", and a number that is set off by a "/" may begin with a "0".
Furthermore, the rules governing numerical expressions depend not only on the


As I’ve gotten involved with helping the WordPress.org theme review team, I’ve seen some strange things. One of the stranger ones was a theme virus that actually propagated from one theme to all others in a WordPress installation. That one was awfully clever, but it ultimately didn’t really do anything but propagate and generally be a pain in the ass.

However, today, @chip_bennett discovered that one of his themes had been copied and was being redistributed by a site called top-themes.com.

It had malware inserted into it that is of a much more malicious and spammy nature. Further investigation reveals that ALL of the themes on that site contain basically the same code. This code is not actually “viral”, but it’s definitely malware and it’s worth investigating to see someexception I’ve found is Leland’s Themes at ThemeLab. I don’t know if I would trust any other extra-repository, free-Theme distributor.

Given the state of the free-Theme environment right now, I am fairly confident in saying: buy a commercial Theme from a reputable developer, or get a free Theme from within the WordPress.org Repository. Anything else, and you will almost certainly get a compromised Theme.

I’m wondering if it would be possible to develop some sort of WPORG-hosted digital-signature database against which to verify Themes?

Outside of that, Theme developers are going to have to start looking at registering their Theme names as Trademarks, and then enforcing those Trademarks. Unfortunately, this route is very likely prohibitively expensive for free-Theme developers.

Nice analysis! And I didn’t even realize that PHP had a pack() function,


of your own family. Maybe those random movements weren't so random after all.

2 comments:

For what it's worth, I have the next stage of the same problem, but from an unexpected source, perhaps... My GG GF's younger brother, Robert Constable Bruce (1841-1924) emigrated from Dundee, Scotland, to San Francisco in 1863 (via Cape Horn). Not the most obvious time for someone to emigrate to America. I can only imagine his move had something to do with someone spotting a commercial opportunity, possibly to do with Dundee's textiles - he joined an import / export business in SF and ended up a partner in it, so he was certainly talented in business (a trait his elder brother, my GG GF, did not share going bankrupt - or nearly so -soon as I’ve reached a good amount of players. You can also contact me through Twitter: @GeekishGaming. Feel free to contact me with any questions you might have.

Hope to be gaming with you soon,

Kevin

(EDIT: The contact form is currently down. I’ll work to get it back up as soon as I can. In the meantime, please contact me through Twitter.)

(EDIT 2: Form is back uo again. Sorry for the inconvenience!)


leaves, or coming to an urban intersection where a generation of cars has marinated the asphalt in old 10W-30. And if you’re just a commuter or fair-weather rider caught out by a cloudburst, you don’t have the benefit of full-wet race tires. But, mere mortals can use some of the same techniques racers use to bring it home safely.

Don’t snatch that brake! Start with a gentle squeeze to transfer weight to the front and push water out of the way.

Even though, as an ex-racer, I trust my front brake in the wet, I often use my rear brake to reduce rear-wheel momentum and initiate braking. A lot of street riders shift almost all their braking emphasis to the rear in the wet; that’s OK at slow speeds, but "That's Life" (Live at The Point) - 4:30
  "Benediction" (remix) (with Georgie Fame & Ben Sidran) - 3:01
  "The Healing Game" (remix) - 5:17
  "I Don't Want to Go On Without You" (with Jim Hunter) - 3:27

Disc two
  "Shenandoah" (with The Chieftains) - 3:53
  "Precious Time" - 3:08
  "Back on Top" (remix) - 4:20
  "When the Leaves Come Falling Down" - 5:38
  "Lost John" (Live at Whitla Hall) - 2:57
  "Tupelo Honey" (with Bobby "Blue" Bland) (previously unreleased) - 3:37
  "Meet Me in the Indian Summer" (Orchestral Version) (Remix) - 3:31
  "Georgia on My Mind" - 5:37
  "Hey Mr. DJ" - 3:49
  "Steal My Heart Away" - 4:11
  "Crazy Love" (with Ray Charles)


of small non-coding RNAs (termed sRNAs in bacteria and microRNAs in eukaryotes) ([@gks385-B6]--[@gks385-B9]). Approximately 40% of known transcription factors in *Escherichia coli* are subject to negative transcriptional autoregulation (NTAR) ([@gks385-B10],[@gks385-B11]). Several functions have been proposed for the widespread NTAR motif, including speeding up the response time of transcription networks to reach steady-state ([@gks385-B11]), linearizing the dose--response relationship of a downstream gene ([@gks385-B12]), and the control of noise ([@gks385-B13],[@gks385-B14]). The noise properties of regulation by small RNAs are still poorly understood ([@gks385-B15]), especially so in the case of negative autoregulation (termed NSAR here). Incoherent, microRNA-mediated feedforward loops can couple finetuning of protein means and noise control ([@gks385-B16]).

Previous theoretical work has reported that NTAR can suppress intrinsic noise ([@gks385-B17],[@gks385-B18]). As we will see, relying exclusively upon one of the twosystem that is identical except for the absence of the negative feedback loop---the system with all other rate parameters unchanged. Results holding the mean protein expression level constant are also given to facilitate comparison with some previous work. We provide results that are valid when all parameters are allowed to vary within broad, biologically plausible ranges and that are exact (up to Monte Carlo sampling error). By contrast, the accuracy of analytical approximations deteriorates for low numbers of molecules when reaction kinetics are non-linear due to the presence of bimolecular reactions such as promoter binding and complex formation by sRNA with mRNA. Figure 1.Comparing suppression of the mean and fluctuations of protein under transcriptional and sRNA-mediated negative autoregulation. Results for 2000 parametrizations of each feedback control system, selected


uniformly from the biologically plausible rate parameter space (Supplementary Data). (**A**) NTAR with the reactions added to the unregulated system to obtain the corresponding NTAR system shown in red. (**B**) NSAR, with the reactions added again shown in red. Complete descriptions of both reaction networks are in [Supplementary Table S1](http://nar.oxfordjournals.org/cgi/content/full/gks385/DC1). (**C**) For NTAR, the ratio of the variances of the number of protein molecules in the regulated (r) and unregulated (u) systems, as a function of the ratio of the corresponding means (using logarithmic axes). Each point corresponds to a pair of rate parameter vectors (one each for r and u): rate parameters present in both systems are held constant. The colour bar shows the logarithm of the ratio of average cost per molecule of mean expression (perhence no cooperativity in promoter binding.

For both mechanisms NTAR and NSAR (detailed in [Supplementary Table S1](http://nar.oxfordjournals.org/cgi/content/full/gks385/DC1)), the mean of the protein level is always reduced on the addition of negative feedback compared to the unregulated mean, typically more so for NTAR than for NSAR. The strength of variance suppression by the two feedback mechanisms can be assessed by comparing the loci of points in panels C and D of [Figure 1](#gks385-F1){ref-type="fig"}. For a given reduction in (the logarithm of) the mean, a greater reduction in (the logarithm of) the variance indicates stronger suppression. These reductions do not depend on the units in which protein levels are measured. Broadly speaking, NSAR suppresses the variance more strongly than NTAR. However, suppression by NSAR is more sensitive to rate parameters than


(squared) deviation of the protein level from the mean over a long time period (for an ergodic system). Biologically relevant timescales over which some form of time-averaging by downstream modules takes place may be considerably shorter, in which case the lifetime of excursions away from the mean becomes important. This lifetime can be measured by the autocorrelation function for the protein level and its autocorrelation time. We have quantified and explained analytically how beneficial reductions in both the autocorrelation time ('noise whitening') and in the relative variance of a transcription factor combine to control the noise in downstream gene expression, for the case of proportional transcriptional activation. We find that transcriptional autorepression whitens noise more substantially and reliably, compared to small RNA-mediated negative autoregulation.

We have provided an extensivemiR-20a/E2F1, miR-195/E2F3, miR-19b/MYCN, miR-9/NFKB1, miR-25/PTEN, miR-27a/RUNX1, miR-21/STAT3, miR-410/CDKN2A, miR-302a/SOX2.Predicted by us (see Supplementary Data) using bioinformatics databases (53 pairs identified using TransmiR ([@gks385-B35]) and microRNA.org databases) or found in the literature ([@gks385-B36],[@gks385-B37]) (8 pairs).*Caenorhabditis elegans*23miR-43/Lin-26, miR-48/DAF-3, miR-236/Lin-26, miR-80/ODR-7.Predicted from bioinformatics data by ([@gks385-B38]). Negative and positive feedback loops not distinguished.*Escherichia coli*4OmpA/OmpR, OmrB/OmpR, GadY/GadX, RybB/RpoE.Identified by us using the RegulonDB dataset of regulatory interactions ([@gks385-B39]) (3 pairs) or in the experimental literature ([@gks385-B40]) (1 pair).[^1]

It would be interesting to perform similarly detailed comparisons in the presence of extrinsic noise, although exactly how to specify the extrinsic processes is challenging. Previous work considering transcriptional autorepression and extrinsic noise points to the existence of an optimal feedback strength ([@gks385-B20],[@gks385-B27],[@gks385-B33]). Experiments using chromosomal rather than plasmid-borne genes should be performed to compare


threefold, that v=-2+h\^[2,1]{}(B\^3).

Now in constructing specific $F$-theory fourfolds, we make use of the fact that the heterotic $CY^{19,19}$ is a ${\bf Z}_2$ orbifold of the space $K3\times T^2$, which represents the geometric starting point for a heterotic $N=2$ compactification. As explained in the appendix A.2 the $dP$’s in the $CY^{(19,19)}$ arise in two different ways, namely either by [*‘emergence’*]{} or by [*‘reduction’*]{} from $K3\times T^2$ (the differences will show up again in two different choices of heterotic gauge bundles). Therefore on the $F$-theory side again two possible $Z_2$ moddings present themselves naturally. First $X^4$ might be obtained by modding out the corresponding ${\bf Z}_2$ involution on $T^2\times CY={\tiny
\left[\begin{array}{c|cc}P^2_x&3&0\\P^1_y&0&2\\P^1_z&0&2\\P^2_w&0&3
\end{array}\right]}$ (model A), i.e. the model is a $Z_2$ orbifold of the type IIA string on the $CY={\tiny \left[\begin{array}{c|c}P^1&2\\P^1&2\\P^2&3\end{array}\right]}$. Onof the modded $N=2$ parent model is simply the modded spectrum of the $N=2$ model. For this note that in (leaving out the intermediate step over $X_{11}(j)$)

[ccc]{} K3\_[10-6]{}T\^2\_[6-4]{}& &CY\^[19,19]{}\
-ell\_[K3]{}& & -ell\_[dP\_[10-6]{}]{}\
P\^1\_[K3]{}T\^2\_[6-4]{}& &dP\_[8-4]{}

a bundle V over $CY^{19,19}$ - to be considered as being modded from the $N=2$ situation on the left hand side - has by consistency to pullback to a bundle ’living’ (varying) purely in the K3-sector, i.e. V must not vary along $ell_{dP_{8-4}}$. So the spectral surface $C^2_{spec}$ (at first over $X_{11}$ in the intermediate step, say) is double covered (with branching only in codimension two) by $C^1_{spec}\times T^2_{6-4}$ with $C^1_{spec}$ the spectral curve of the $N=2$ parent model on the left. So counting the deformations in the spirit of [@BJPS] one finds that again by $h^{2,0}(C^2_{spec})=h^{2,0}(C^1_{spec}\times


modular weight $-2$ is around the minima $w_i^0$ simply given by a $\tau$-independent mass term ($\mu$-term) for the fields $\phi$ W\^|\_[SUSY]{}\~q\_9\^2.\[wprimesusy\] To argue for this correction by $\eta^{-12}$ we can compare with a precise rational curve counting on the del Pezzo provided by mirror symmetry [@KMV]. In the $CY^{3,243}$ over $F_1$ (where $dP$ occurs over the exceptional section of the $F_1$ base) one finds among the instanton numbers n\_[0,1,k]{}q\^k=, where the zero index indicates that we are considering the del Pezzo sector of the threefold and the 1 indicates that inside the del Pezzo itself one has $C\cdot f=1$ as intersection with the elliptic fibre of del Pezzo; i.e. considering the $n_{0,1,k}$ sector implements exactly the counting we want to do. Now in the del Pezzo lattice $H\opluspreserving minimum ($W=0$, $dW=0$) $\phi_{1,i}=\phi_{3,i}=0$. Therefore the vacuum expectation values of the Wilson line fields $\phi_{1,i}$, $\phi_{3,i}$ are set to zero after the minimization, i.e. the vacuum expectation values are not free, continuous parameters in the presence of this superpotential. Going away from the minimum of the superpotential by turning on the Wilson line fields $\phi_{1,i}$, $\phi_{3,i}$ means in the context of conformal field theory, that one is in fact going away from the conformal point, i.e. going off-shell.

Finally let us also remark on the factor $q_9$ in eq.(\[supwi\]). In the orbifold limit the possible $z_9$-depedence of the superpotential is again restricted by $T$-duality. However the duality group with respect to the modulus $z_9$ is no longer the full modular group $PSL(2,Z)$ but only a subgroup of it,


Vafa, [*Evidence for F-Theory*]{}, Nucl. Phys. [**B469**]{} (1996) 493, hep-th/9602022.

E. Witten, [*Nonperturbative Superpotentials in String Theory*]{}, Nucl. Phys. [**B474**]{} (1996) 343, hep-th/9604030.

R. Donagi, A. Grassi and E. Witten, [*A Nonperturbative Superpotential with $E_8$ Symmetry*]{}, hep-th/9607091.

R. Gopakumar and S. Mukhi, [*Orbifold and Orientifold Compactifications of F-Theory and M-Theory to Six and Four Dimensions*]{}, hep-th/9607057.

O. J. Ganor, [*A Note on the Zeroes of Superpotentials in F-Theory*]{}, hep-th/9612077.

I. Brunner and R. Schimmrigk, [*F-theory on Calabi-Yau Fourfolds*]{}, Phys. Lett. [**B387**]{} (1996) 750, hep-th/9606148;\
I. Brunner, M. Lynker and R. Schimmrigk, [*Unification of M-theory and F-theory Calabi-Yau Fourfold Vacua*]{}, hep-th/9610195;\
P. Mayr, [*Mirror Symmetry, $N=1$ Superpotentials and Tensionless Strings on Calabi-Yau Four-Folds*]{}, hep-th/9610162;\
S. Katz and C. Vafa, [*Geometric Engineering of $N=1$ Quantum Field Theories*]{}, hep-th/9611090;\
M. Bershadsky, A. Johansen, T. Pantev, V. Sadov and C. Vafa,by abuse of language we do not distinguish between the curves and their homology classes

[^7]: Essentially $A_i=E_i-E_{i+1}$, where a $C$ then has coordinates $m_i$, say, instead of the $n_i$, and $w_i=z_i-z_{i+1}$, $i=1,...,7$; cf. [@DGW] for details; $z_9$ is the Kähler modulus of the the base $P^1_y$; $\tau$ is the Kähler modulus of the fibre $T^1_x$, and the $w_i$ correspond to the $E_8$ part; note that $m^2:=\sum_{i=1}^8 m_i^2-(m_1m_2+\cdots +m_6m_7+m_3m_8)$ is $-\frac{1}{2}$ times the $\vec{m}^2$, say, built with the intersectionform of the (negative definite) $E_8$ intersection lattice

[^8]: Namely $u=1-2\frac{\theta_2^4}{\theta_3^4}=\frac{\theta_4^4-\theta_2^4}{\theta_3^4}$ gives (using that $\theta_{3\mbox{\, resp.}2}^4=8\frac{1}{2\pi i}\partial _{\tau}\log
    \frac{\theta_{2\mbox{\, resp.}3}}{\theta_4}$ (cf. [@DK]) so that $4\partial _{\tau}\log \frac{\theta_2}{\theta_3}=\pi i \theta_4^4$) that $\partial _{\tau}u=(u-1)\partial _{\tau}\log (1-u)=
    (u-1)4\partial _{\tau}\log \frac{\theta_2}{\theta_3}=(u-1)\pi i \theta_4^4=
    -2\pi i\frac{\theta_2^4\theta_4^4}{\theta_3^4}$, so $\frac{\partial


which is also a number of quite visible origin: ${\cal B}$ can be considered (cf.[@DGW]) as the blow-up of ${\scriptsize \left[\begin{array}{c}P^1\\P^2\end{array}\right]}$ at the base locus $\Gamma:={\scriptsize
    \left[\begin{array}{c|cc}P^1&2&2\\P^2&3&3\end{array}\right]}$ of the pencil of K3 surfaces. The cohomology class of $\Gamma$ is $-2J_1-3J_2$, denoting by $J_i$ the respective classes coming from the factors, so $e_{\Gamma}=-\Gamma^2=-54$ (showing again $e_{{\cal B}}=6-54=-48$), i.e. $\Gamma$ has genus 28.
smoking a bit. Then a piece fell into the hole and down into the wall where it sat and smoked for a while. A couple of squirts from my trusty fire extinguisher, and all was well.

The kind of plaster makes a difference. There is hard stuff and soft material that seems to be as much animal hair or other filler as it is plaster.

It is often easier to use a wood chisel and mallet to tap an outline in the soft material then remove the material inside the outline with light taps on the chisel. Then the lath can be cut - I usually use a very fine tooth in a sabre saw as the plaster will destroy a Roto-Zip bit or 2 per opening. Usually I only


able to work in plaster walls without tearing them up.

The Following User Says Thank You to itsunclebill For This Useful Post:

Just cut a bunch of boxes into some 100 year old horsehair plaster. I used my dremel tool with a fine cutting wheel to score the plaster, removed it, and a spiral bit to cut the lath. Worked great, except the spiral bit got that old lath to smoking a bit. Then a piece fell into the hole and down into the wall where it sat and smoked for a while. A couple of squirts from my trusty fire extinguisher, and all was well.

Receps turned out great.

Fire has always been on my mind with the rotozip cutting. What if it was smouldering and you didn't know and itapp's real potential." "Revived Media has stepped in to give Developers who want the world to find their app the easiest way and most efficient tracking to do just that," said Ralph Ruckman, Managing Partner of Revived Media.

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of the Guthrie family in northeast Scotland in the early 1900s. The family is led by a patriarch (Peter Mullan) who is prone to anger and has caused his fearful wife to retreat into silence. Chris, their beautiful and intelligent daughter, and her brother Will dream of freedom and escape from their situation and the village in which they live. Freedom comes suddenly and Chris eventually finds happiness in the form of newcomer Ewan Tavendale. Unfortunately, Chris’ newfound happiness is not to be. Despite their change in fortune, the lives of Chris, Will, Ewan and everyone else are ultimately disrupted by the beginning of WWI. Sunset Song opens in Toronto today and in select cities across Canada later in May and into June. Click here for showtimes.Trailer: Sunsetdon't like storing photos, because they are only ephemerally relevant, whatever few photos I take, go to [Flickr](http://www.flickr.com/photos/nimbupani "Divya's photos on Flickr."). I have [Microsoft Office][office] out of necessity of dealing with antiquated documents that I sometimes get sent.

I use [zsh][] with [oh-my-zsh][]. This is where most of my work gets done. I use [MacVim][] for coding. [Python][]'s SimpleHTTPServer is sufficient for setting up a local server. For shared testing, I use Dropbox's Public folder if I need to share it with someone else. Any code goes into a git repo that is either deployed to [Github][] or other remote git repos. For quick bug testing, [jsfiddle][] or [jsbin][] are my tools of choice along with [Opera Dragonfly][dragonfly]. I also have the latest stable releases of [Chrome][], [Firefox][],


Electron-Deficient Alkynes as Dipolarophile in Pd-Catalyzed Enantioselective (3 + 2) Cycloaddition Reaction with Vinyl Cyclopropanes.
The activated alkynes have been used successfully for the first time as the dipolarophile in the palladium-catalyzed asymmetric (3 + 2) cycloaddition, affording highly functionalized cyclopentenes in good to high yields with high chemoselectivities and good to high enantioselectivities. The introduction of an additional carbonyl group at the α-position of the alkynyl esters is the key to activating the carbon-carbon triple bond. The reaction process was investigated, and an inverse process of Pd-catalyzed (3 + 2) cycloaddition was observed.an old-fashioned centralized system, but it's a bit of a pain to set up imo. Requires special software on the server.
I personally am quite fond of Bazaar, which is distributed, and a server repository only requires FTP access and nothing else on the server.

A:

Eric Sink has written a nice Source Control HOWTO.
Disclaimer: Eric Sink is a principal of SourceGear which develops and sells several source control-related tools (including SourceGear Vault).  However, the Source Control HOWTO is a pretty neutral, balanced writeup.

A:

Version control systems aren't just for large teams! The individual developer working on a hobby project has much to gain from versioning their code.
Most version control systems are centered around the concept of a repository, which is managed by the system and never touched directly. When you


50, 15, and 33 differentially expressed gill proteins, respectively. Venn diagram analysis revealed substantial different responses to the three stressors. Only xanthine dehydrogenase/oxidase showed a similar expression pattern across the three stress treatments, suggesting that reduction of ROS accumulation may be a conserved response to these stressors. Heat shock caused significant overexpression of molecular chaperones and production of S-adenosyl-l-methionine, indicating their crucial protective roles against protein denature. In addition, heat shock also activated immune responses, Ca(2+) binding protein expression. By contrast, hyposalinity and aerial exposure resulted in the up-regulation of 3-demethylubiquinone-9 3-methyltransferase, indicating that increase in ubiquinone synthesis may contribute to withstanding both the osmotic and desiccation stress. Strikingly, the majority of desiccation-responsive proteins, including those involved in metabolism, ion transportation, immune responses, DNA duplication, and protein synthesis,seclusion, away from everyday city life. I normally run off to my mother’s home in Bodrum Turkey, whereby I spend quality time with my sketchbook, pencil set, and the sounds of crashing waves.

Where is your go-to meeting spot?

I don’t have a set go-to meeting spot but I try placing myself in “fun” surroundings, as I always try blurring the line between the seriousness of work with the joy of life!

How would you describe your customer base?

There is no set demographic to my customer base in terms of age or demography, but they all share one thing in common; their urge to express their personal style. Most of my designs can be worn in a multitude of ways, and this allows my customers to bring out their inner artist.

Is


work you particularly admire?

I, for creative purposes, do not follow the works of any jewelry designers. I do however admire Stella McCartney simply because she has been revolutionary in her standpoint against animal cruelty.

What’s the best piece of advice you’ve ever been given?

Listen to your heart. Believe in your self. Nothing is impossible.

What drew you to Wolf & Badger?

I have always been a supporter of independent artists, and basically, the black sheep movement. As both a person and as a brand, conformity is not one of our pillars, which I found is a view shared with Wolf & Badger.

Where do you see the brand in 5 years?

I see MSJ by Mira S. Designs as an internationally renowned brand that is synonymous with both unique design and social contribution.nanoparticles, but blue shifting to the positions of 1,160.97 cm^−1^ for the C-O-C stretching vibration and 1,681.87 cm^−1^ for the C-H bending vibration, respectively. Noticeably, the absorption intensities and vibration and bending shapes vary between the pure PEO-PPO-PEO molecules and the PEO-PPO-PEO-capped Cu-ZnO nanoparticles. The shape change and blue shifting in the C-O-C stretching and C-H bending modes may be due to the interactive coordination of the oxygen atoms in the PEO-PPO-PEO main chains to the Cu and Zn atoms in the hybrid nanostructure which could be attributed to changes in the elastic constants of the bonds of the macromolecules sitting on the nanoparticle surface of high curvature owing to the small nanoparticle size and interactions between the macromolecules and the nanoparticle surface \[[@CR27]-[@CR29]\]. Mine while, the double C-H stretching


dispersible function intended for an easy transport of the nanoparticles between polar and non-polar solvents without further surface decoration. Figure [5](#Fig5){ref-type="fig"}a (a to d) shows the UV--vis spectra of the PEO-PPO-PEO-capped Cu-ZnO hybrid nanoparticles dispersed in ethanol, hexane, and water, together with that of ZnO nanoparticles dispersed in hexane. Apparently, Cu-ZnO hybrid nanoparticles exhibit two kinds of absorption bands. The strong absorption bands observed around 367, 368, and 369 nm for the spectra of the Cu-ZnO hybrid nanoparticles dispersed in ethanol, hexane, and water, respectively, are assigned to the most characteristic absorption of ZnO semiconductor \[[@CR35]\], which correspond to red shifting from the absorption band of the ZnO nanoparticles in hexane at the position of \~364 nm. The red shifting of the polymer-capped Cu-ZnO hybrid nanoparticles may be explained in thesystem is based on the generation of electron--hole pairs. When light with energy higher or equal to the band gap energy is irradiated to the ZnO surface, the transition of photoelectrons from the valence band (VB) to the conduction band (CB) may be promoted, leaving behind a hole in the valence band. The photoelectrons may be captured by the O~2~ on the surface of ZnO for the formation of O~2~^•−^ radicals, while the holes react with ethanol in order to generate ethoxy radicals. The ethoxy radicals and O~2~^•−^ radicals are found to be major species responsible for organic dye degradation \[[@CR49],[@CR50]\]. The weak photocatalytic activity of ZnO nanoparticles may be due to the quick recombination of photo-generated charge carries. The Cu-ZnO hybrid nanoparticles likely result in a lower


or do paperwork — and he will look inattentive. But it’s not ADHD.

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Now, as a physician, I get it. The information just isn’t out there —that’s why it took me years to figure this out. I missed it. Our doctors missed it. Our teachers and social workers and, yes, the nurses missed it. The only thing we’ve all ever heard of is ADHD, so these other disorders aren’t even considered.

On the other hand, there really is no excuse for overlooking food allergies — and they are surprisingly common. Milk allergy is the most common food allergy, affecting 2 to 3 percent of us and probably higher in children. Wheat and soy allergies are increasingly common. Unfortunately, milk and wheat are everywhere in school. (Imagine how these kids feelWatch your ass." " Ow ow ow ow!" "You could have killed me back there." "If I wanted to kill you, you'd be dead." "I wanted to graze you, you're grazed." "It was a training bullet." "Well, I'm bleeding, although you might call it "training blood."" "Here, use this." "Taco sauce?" "Yes, it's a natural antiseptic." "Sprinkle some of that on your ass so you don't get an infection." "Yeah, well, I don't even wanna know how you discovered that." "So what, you keep this in your glove compartment and just splash it on a salami sandwich and then splash some on your behind?" "Use it or don't use it." "It's your ass." "You got any guacamole in there?" "I hear it makes a great cold compress." "


"How can you not trust your mother?" " She could be playing me." " How can a person go through life like that?" "Hey, at least I'm honest about it." "What, you trust everybody you meet?" "I give everybody the benefit of the doubt, yes." "And what happens when they screw you over?" "Who's gonna screw me over?" "What, do you think people are just waiting to screw people over?" "You think the world is one big screw-over?" "I couldn't live my life like that." "I never met anyone" "I wasn't friends with eventually." "Well, I never met anyone whose ass I didn't kick eventually." "Well, you must be very proud." "Guns and shooting and kicking ass." "You know, problems can be solved without ever touching a gun."groups, in case reports from a 19-month-old girl\[[@ref8]\] to adults.

The most familiar agents are organophosphate compounds, but Abamectin, Carbamat, Avemectin, Chwastox and finally Pyrethroid intoxication are reported in the literature. In organophosphate intoxication some related and defined clinical manifestation like motor neuropathy, mixed sensory motor polyneuropathy and myelopathy have been reported,\[[@ref9][@ref10]\] but there is no uniform description of signs and symptoms in other pesticide. Most of the authors reported neurologic manifestation of organophosphate compounds as a delayed sensory motor polyneuropathy\[[@ref11]\] and rarely pure motor and rapidly evolving myelopathy. In a study in India, Guillain-Barre like syndrome is seen in intoxication with organophosphate poisoning. In this case neuropsychiatric disorders are defined as a chronic manifestation of this poison.\[[@ref12]\] Our case presented with similar rapidity in onset, but was unusual


Learning What It Means to Feel Empowered

A few weeks ago we went to a seminar about ‘Sexism in Everyday Life’ and it was one of the best experiences I’ve had in a while.

Right now, I’m doing a volunteering year as gap between school and university. I’ll make a post about the whole thing soon because it’s kind of hecking awesome, but all you need to know for this is that we can attend about any form of seminar as part of the year.

One of my friends here is recently getting interested in lots of social issues and found a seminar about ‘Sexism in Everyday Life‘ which was held in Bremen – about 4 hours from here. It’s also one of the cities I consider going to uni in,"-maxiter",100);
    nm = nmplot_configure(nm, "-maxfunevals",300);
    nm = nmplot_configure(nm, "-tolxmethod",%f);
    nm = nmplot_configure(nm, "-tolsimplexizerelative",1.e-8);
    nm = nmplot_configure(nm, "-simplex0method","spendley");

    //
    // Setup output files
    //
    simplexfn = TMPDIR + filesep() + "history.simplex.txt";
    nm = nmplot_configure(nm, "-simplexfn",simplexfn);

    //
    // Perform optimization
    //
    mprintf(_("Searching (please wait) ...\n"));
    nm = nmplot_search(nm);
    //
    // Print a summary
    //
    exec(fullfile(dname,"nmplot_summary.sci"),-1);
    nmplot_summary(nm)
    //
    // Plot the contours of the cost function and the


including how his own immigrant experience has meshed with his expertise in Machine Learning to help produce Eightfold’s AI and Machine Learning driven tools to close the talent gap. For Ashutosh and everyone at Eightfold, the US is the arena where the world’s top talent can make the most of its abilities, and Eightfold is working to make that talent as accessible as possible to firms that need it to drive the world’s innovation.of times before the first photoresist is developed.
Thereby, a complicated pattern can be dealt with.
In the above described method for the formation of a semiconductor device pattern, the second exposure is, preferably, carried out a plurality of times before the second photoresist is developed.
Thereby, a complicated pattern can be dealt with.
A method for designing a photo mask pattern according to the present invention includes the following steps.
First, figure parts of microscopic line pattern is extracted from a design pattern layout. And the line width W2 of the mask dark lines in the figure parts of microscopic line pattern is adjusted so as to satisfy the relationship of 0.35 less than W2/(xcex/NA), wherein the wave length of exposure light is denoted as xcex and the numerical aperture of the


were set to be the frightening offensive team they were at the end of last season. That lasted about a week, and it wasn’t only because Kaepernick’s next stop was Seattle. In the next two months, Kaepernick threw for more than 200 yards just once while the Niners’ offense limped along. Some of that was a renewed commitment to the run in Weeks 4-8 (a stretch in which San Francisco managed to put up more than 30 points per game thanks to a mix of Kaepernick and Frank Gore running over defenses), but anyone watching could see that this was a passing game that wasn’t quite right. That feeling was only confirmed when San Francisco dropped its next two games as Kaepernick threw for 218 total yards.

There arefrom bssbmmnmmesnnbo. What is prob of sequence senb?
3/3640
Two letters picked without replacement from uuutuuutu. What is prob of sequence ut?
7/36
Calculate prob of sequence hzhr when four letters picked without replacement from {h: 2, o: 1, r: 3, z: 1}.
1/140
Three letters picked without replacement from {n: 5, l: 2}. Give prob of sequence lnn.
4/21
Two letters picked without replacement from {f: 1, w: 3, h: 2, c: 4, t: 1}. What is prob of sequence cc?
6/55
Two letters picked without replacement from {d: 5, g: 2, c: 3, v: 1, z: 5}. Give prob of sequence vg.
1/120
Four letters picked without replacement from {l: 4, c: 3, s: 2, u: 6}. What is prob of sequence uuus?
2/273
Two letters picked without replacement from {q: 2, n: 1, r: 3, h: 2, e: 3,


ppfpffpfppppfpfppfp. Give prob of sequence pff.
28/323
What is prob of sequence uvb when three letters picked without replacement from uyerbvv?
1/105
Calculate prob of sequence rrrr when four letters picked without replacement from rrrrr.
1
Three letters picked without replacement from {j: 4, a: 10}. What is prob of sequence jaj?
5/91
Two letters picked without replacement from {c: 3, h: 3, d: 2, v: 1, g: 3, n: 1}. What is prob of sequence ch?
3/52
Calculate prob of sequence yy when two letters picked without replacement from {y: 3, e: 3, b: 7}.
1/26
Two letters picked without replacement from uraururu. Give prob of sequence uu.
3/14
Calculate prob of sequence wnw when three letters picked without replacement from wnnwwwwwwwwnww.
55/364
Three letters picked without replacement from {n: 5, o: 2, x: 7}. Give prob of sequence nno.
5/273
Calculate prob of sequenceDevices for water supply and sanitary purposes which involves purification and recycling or discarding of water are known. One such example, called a hybrid device, is disclosed in WO 2013/095278. In WO 2013/095278 there is disclosed a hybrid device for a recirculation shower, allowing purification and either recycling of water or discarding of water, said hybrid device comprising a recirculation loop, a filter system with a nano-filter, at least one filter quality sensor, and at least one pre-filter, said hybrid device being arranged to redirect the water from recirculation to drainage when the at least one filter quality sensor indicates the need thereof.
One aim of the present invention is to provide an improved apparatus for water supply and sanitary purposes, which apparatus is easier to control and install


within its gates so I didn't realise the severity of [the fire] until we got home," user littlegraythread wrote.

The fire burning through the canyons in Orange County was one of many blazes to hit California on Monday (local time).

Fires in California's wine country, an area in the north of the state, broke out nearly simultaneously and then exploded overnight, sending residents fleeing as embers rained down and flames raged around them.

At least 10 people have been killed and at least 100 have been injured in the fires, and the death toll is expected to grow.

ABC/AP

Topics: social-media, fires, human-interest, united-statesto $SI_{{x +}1}^{}$ was significantly lower than that of $SI_{x}^{}$, $SI_{x}^{}$ matched the typical morphological attributes of the building clusters that might exist in the scene. Therefore, it was necessary to consider $SI_{x}^{}$ as a typical interval, and the corresponding scale parameters need to be retained to ensure that the connected areas corresponding to $SI_{x}^{}$ could be effectively extracted during the differential processing.

Step 4: Traverse all intervals and use all optimized scale parameters extracted to form the final scale parameter set $T_{opt} = \left\{ T_{0},T_{1},\ldots,T_{W} \right\}$. Then, the proposed AMAP--OBC could be produced based on $T_{\mathit{opt}}$ and under object boundary constraint.

Step 5: Conduct DAP by the steps introduced in [Section 3.1](#sec3dot1-sensors-19-03737){ref-type="sec"}. On this basis, the pixels in each DAP that conformed to the attribute range of the building


shook her hand yet. She was gorgeous. He approached her with a smile, “I’m Lucan Vintari.” The young man extended his hand. He had been gone for nine years, it was reasonable that he wouldn’t recognize his cousin.

"I know who you are, Cousin," Isis replied idignantly, sipping at her drink again before placing the cup back down on the table. She turned to Lucan then and stared hard at him before coming to a sudden realization. "You really don't recognize me at all, do you?" She said with a laugh, smiling at her cousin, "Those Clanners must have messed you up more than I thought."

As Lucan looked into the woman’s eyes realization hit him. “You were eleven when I left.” He said softly. “And you never wrote.” Hecooling components, expensive high-pressure hydraulic pumps that sense the load requirements and adjust the velocity of linear or rotary actuators, expensive high-pressure hydraulic valves used to limit horsepower and control the force and velocity of hydraulic actuators, high-pressure hydraulic directional valves to control the direction of movement of the linear or rotary hydraulic actuators, and expensive remote sensing devices that signal the velocity of the linear or rotary hydraulic actuators.
Hence, current centralized high pressure hydraulic systems require considerable physical space for both the placement of the central system and the associated piping. Many times a specific room is utilized or required to enclose the central system.
Furthermore, current centralized high pressure hydraulic systems and methods utilize electric motors as a “prime mover” which are repeatedly started and stopped thereby


The present invention relates to low voltage vacuum switches which are typically used in electrolytic chemical processing plants. The switches are used as shorting switches for shunting around a single series-connected electrolytic cell. Numerous such electrolytic cells are connected electrically in series to a D.C. plant power supply which provides several thousand amperes continuous current and an overall supply voltage of up to about 400 volts D.C. Since these cells are series-connected, and there may be up to about 100 such cells in series with approximately equal resistive characteristics, the voltage across an individual cell is about 4 volts D.C.
The vacuum switches are shunting switches for bypassing an individual cell without shutting down the plant. When a vacuum switch is in the closed contact position, effectively shunting theroll back the 2014 Cole Memorandum, which guided federal prosecutors away from targeting marijuana businesses operating legally under state law.

The Cole Memo was a federal response to the growing shift in public opinion given the number of states "that have moved to legalize marijuana for medicinal, agricultural or recreational use."

Attorney General Jeff Sessions (Gage Skidmore | flickr)

The Sessions memo sent ripples through a cannabis industry already struggling to fund state legalization under contradictory federal laws, but those who have been on the front lines of the legal battles responded forcefully. As Maria McFarland Sánchez-Moreno, executive director of the Drug Policy Alliance, said:

Jeff Sessions' obsession with marijuana prohibition defies logic, threatens successful state-level reforms and flies in the face of widespread public support for legalization. Rescinding the Cole memo


in a CAN. This is, so to speak, an ultimate compact projector including only one light source (1CAN3LD), one condenser lens (CL) and one two-dimensional deflecting mirror. This is a very simple configuration, but includes difficult technologies to realize, such as 1CAN3LD.
As mentioned above, various light paths have been considered, and the deflecting mirrors are commonly arranged diagonally to a beam optical axis. This seems natural because the beam is reflected, but is a large hurdle to overcome to achieve greater compactness of the projector.
In consideration of downsizing the scanning image displayer (laser projector), two single-deflection deflecting mirrors in Japanese Patent No. 4174420 and Japanese published unexamined application No. 2008-275930 are noticeably disadvantageous, whereas a two-dimensional drive deflecting mirror is definitely used for a laser projector aiming atso. But on a lovely Sunday afternoon? Man, that’s extra cold.

Here’s how fans handled the news of AB’s digits hitting the interwebs. It seemed to reverberate a bit in Cleveland, which seems to have a bit of AB envy.

How Cleveland reacts to Antonio Brown's number getting tweeted by an IG model pic.twitter.com/3LgXefeWUy — Brody Logan (@BrodyLogan) June 11, 2017

Funny stuff, even if it’s gallows humor for Brown. He seems to have some bad luck with social media. Who could forget the infamous Facebook live incident after the divisional round playoff victory? Teammate Le’Veon Bell also recently was called out for sliding into the DMs of an online model, so there might be a lesson here.

Of course, life is still good for Brown. The Steelers still believe in him,


Eburodacrys rhabdota

Eburodacrys rhabdota is a species of beetle in the family Cerambycidae. It was described by Martins in 1967.

References

Category:Eburodacrys
Category:Beetles described in 1967NJPW has had agreements with various MMA and professional wrestling promotions around the world, currently with the WWE. NJPW's biggest event is the January 4 Tokyo Dome Show, held each year since 1992 and currently promoted under the Wrestle Kingdom banner.


#!/usr/bin/env python
# -*- coding: utf-8 -*-

import os
import shutil
import datetime
import time

qt_version = "5_9_1"

def p(s):
    now = datetime.datetime.now()
    nowstr = str(now)
    print(nowstr + " > " + s)

def get_version(bpath):
    with open(bpath + "\\ChangeLog.md", 'rb') as f:
        ver = f.readline().split(b" ")[0]
        build_ver = datetime.datetime.now().strftime("%Y%m%d%H%M%S")
        full_ver = ver.decode("utf-8") + "_" + build_ver
        return full_ver

    return None

if __name__ == "__main__":

    bpath = os.path.dirname(os.path.abspath(__file__))

    ver = get_version(bpath)
    if ver is None:
        p("version get error ,SM along with a beautiful unified picture of SM gauge couplings. Among the classes of $SO(10)$ GUTs, supersymmetric versions have multiple features such as successful unification of gauge couplings and natural dark matter candidate owing to an automatic R-parity, while it solves the gauge hierarchy problem based on symmetry principle. In addition, supersymmetric models offer a mechanism for triggering electroweak symmetry breaking (EWSB) via radiative effects [@SUSYREWSB]. In this scenario, the positive mass parameter of the Higgs boson at high energy becomes negative at low energy due to the renormalization group flow which dictates how the parameters evolve with scale.

The purpose of this paper is to explore the possibility of radiative EWSB breaking in non-supersymmetric (non-SUSY) extensions of the SM. Since this is an attractive mechanism to trigger


momentum scale close to the mass of the Higgs scalar.

The outline of the paper is as follows. In Sec. \[sec:SM and type-I\], we discuss the absence of such radiative EWSB in SM and type-I seesaw model. Even though such a mechanism fails for type-I seesaw models, in Sec. \[sec:Type-II Seesaw\] we show that the presence of a TeV scale weak triplet makes radiative EWSB a success for the case of type-II seesaw models. In Sec. \[sec:Two-loop neutrino mass model\], we show that for a two-loop neutrino mass model positive Higgs mass parameter at a high energy scale turns negative in the renormalization group flow to low energy. In Sec. \[sec: IDM\] and Sec. \[sec:scalar singlet DM model\], we show that simple dark matter models such as inert doubletconditions upto the energy scale of new physics such as GUTs.

Using vertex corrections and the wave function renormalization factors, we can calculate the complete set of $\beta$-functions and renormalization group equations (RGEs). We have also determined the RGEs for the mass parameters of the model which are related to the anomalous dimensions $(\gamma_m)$ of the scalar masses by $$\gamma_m \equiv \dfrac{1}{2}\dfrac{d \ln(m^2)}{d t}$$ where $t=\ln \mu_r$ and $\mu_r$ is the running scale. The set of RGEs for the mass parameters is given by [^4]: $$\label{mass RGEs Type-II}
\begin{split}
16\pi^2 \dfrac{d \mu_\phi^2}{d t} =&\[- \frac{9}{10}g_1^2-\frac{9}{2}g_2^2+6\lambda_1+2 T\] \mu^2_\phi +6 \lambda_4 \mu_\Delta^2+6|\mu|^2;\\
16\pi^2 \dfrac{d \mu_\Delta^2 }{d t}  =&\left[\l(-\frac{18}{5}g_1^2-12g_2^2\r)+8\lambda_2+2\lambda_3+2\tr\left(\mathbf{Y_\Delta^\dagger
Y_\Delta}\right)\right]\mu_\Delta^2+4\lambda_4 \mu_\phi^2+2|\mu|^2;\\
16\pi^2 \dfrac{d \mu }{d t} =&\left[\lambda_1+4\lambda_4-8\lambda_5-\frac{27}{10}g_1^2-\frac{21}{2}g_2^2
  +2 T +  \tr\left(\mathbf{Y_\Delta^\dagger Y_\Delta}\right)\right]\mu;\\
\end{split}$$ where $$T =\tr \[\mathbf{Y_e^\dagger Y_e}  +3 \mathbf{Y_d^\dagger Y_d} +3 \mathbf{Y_u^\dagger Y_u}


masses is not naturally suppressed any more [@Merle:2015gea]. We consider TeV scale right-handed neutrino masses to avoid such undesired situation.

The model
---------

The scotogenic version of the inert doublet model requires three right-handed neutrinos $(N_i)$ along with inert scalar doublet $(\eta)$ and the SM particles. All the newly introduced particles are charged under the additional $\mathbb{Z}_2$ parity symmetry while all the SM particles are neutral under this parity. The neutral component of the inert scalar doublet is the only dark matter matter candidate for the general inert doublet model while for the scotogenic case the lightest $\mathbb{Z}_2$ odd particle$-$ either a neutral scalar from the doublet, or the right-handed neutrino $-$ is a dark matter candidate. The survival of the $\mathbb{Z}_2$ symmetry is crucial for the model as this symmetryextension of SM by a real scalar singlet in Fig. \[fig:sample RGE SM\_+ real singlet\]. Note that the mass parameter of the dark matter candidate $\mu_s^2$ corresponds to the value needed for the right amount of thermal relic abundance.[]{data-label="table: sample point SM+real singlet"}

[.5]{} ![One-loop running of the parameters of scalar singlet dark matter model from Planck scale down to weak scale. The black dashed line corresponds to the scale, $\mu_r=\mu_s$. In Fig. \[fig:sub1:sample RGE SM\_+ real singlet\] the evolution of the absolute value of the SM Higgs mass parameter $\left(\left| \mu_\phi \right| \right)$ along with the mass of the dark matter candidate has been plotted. The point at which $\left| \mu_\phi \right|$ touches the horizontal line corresponding to mass =$\;0 \; \text{GeV}$, is the energy scale where radiative


EWSB is triggered as the sign of the SM Higgs mass-squared parameter $( \mu_\phi^2)$ switches from positive to negative while evolving from high to low energies. Note that $\mu_\phi^2$ turns negative around $\mu_r \approx 10^{11} \; \text{GeV}$, while $\mu_s^2$ remains positive all the way up to Planck scale emphasizing the fact that the $\mathbb{Z}_2$ that protects the dark matter candidate remains unbroken. In Fig. \[fig:sub2:sample RGE SM\_+ real singlet\] shows the evolution of all the quartic couplings of the model from Planck scale down to weak scale. Note that the model remains perturbative all the way for the selected sample point.[]{data-label="fig:sample RGE SM_+ real singlet"}](SM_real_singlet_mass_parameters.png "fig:"){width="8cm"}

[.45]{} ![One-loop running of the parameters of scalar singlet dark matter model from Planck scale down to weak scale. The black dashed line$$V=\dfrac{1}{2}\;  \boldmath{x}^T \boldmath{\lambda\, x},$$ where $$\bm{\lambda}=\begin{pmatrix}
\lambda_1 & \lambda_4+\lambda_5 \cos 2\beta & \lambda_4-\lambda_5 \cos 2\beta \\
\lambda_4+\lambda_5 \cos 2\beta & \lambda_2 &\lambda_2+\lambda_3 \\
\lambda_4-\lambda_5 \cos 2\beta & \lambda_2+\lambda_3 & \lambda_2
\end{pmatrix}.$$ We use known results from the copositivity conditions of real symmetric matrices [@Hadeler:1983; @Klimenko:1985] to determine the boundedness conditions as

1.  2.  3.

where $$\det \bm{\lambda}=-2 \lambda_1 \lambda_2 \lambda_3 -\lambda_1 \lambda_3^2+2 \lambda_3 \lambda_4^2-2\left(2 \lambda_2 +\lambda_3\right) \lambda_5^2 \cos^2 2\beta.$$ As this set of boundedness conditions need to be satisfied for all values of $\beta$, this set of conditions reduces to the set of inequalities (\[cond1\], \[cond2\] and \[cond3\]). Note that, all the conditions mentioned in inequalities (\[cond1\]) and (\[cond2\]) and at least one of the conditions in inequality (\[cond3\]) need to be satisfied for the potential to be bounded


the same high-quality training with unbeatable prices that we have been providing to our students at the Greenbelt, Maryland location since 2001.

As a Network Administrator you can expect a career that allows upward mobility and comes with a good salary. According to Indeed, Network Administrators can expect an impressive pay rate in Washington, DC, which is 25% above the national average. So is a job as a Network Administrator right for you? Keep reading to find out more about this profession.

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LEOMINSTER -- The City Council voted Monday night to amend the city's zoning ordinances to insert a recreational marijuana establishment moratorium.

Discussion on the moratorium was limited Monday night, with only Council President David Cormier voting against the amendment.

The council had initially approved the moratorium unanimously when they first voted on it in March. At the time Cormier remarked that he had only voted for it in order to hear from the city solicitor what the consequences of not actually implementing the moratorium would be.

"I don't think it's going to mean much. I think the legislature has put a stop to this until July 2018 anyway," Cormier said after Monday night's meeting. "I think we'd just be wasting our time."

The city's moratorium would


Durham, North Carolina. (See how "Birds Evolved From Dinosaurs Slowly—Then Took Off.")

View Images Carmine bee-eaters are actually the descendants of a predatory bird that likely dashed its victims against hard surfaces when making its kills. Photograph by Michael Nichols, National Geographic Creative

An Odd Duck

That accelerated rate of change in birds—as compared with the rate in "living fossils" like crocodilians and the common ancestor of birds and crocodilians—makes them the odd ducks on this branch of the family tree, says David Ray, a biologist at Texas Tech University in Lubbock.

And while birds evolved at similar rates as mammals, bird genomes are only about one-third the size, he says. They have all the same basic functions as mammals, though, including the capacity for vocal learning.

In fact, one of the excitingparts of this massive project is what Jarvis and colleagues have learned about how birds and people learn unique vocalizations. Through this enormous genetics project, researchers have also pinpointed areas of the brain involved similarly in vocal learning in both birds and people.

Similarities in vocal-learning genes in both groups will allow scientists to use birds in studies of conditions such as stuttering or Parkinson's in people, Jarvis says.

Now that his team has identified the genes for vocal learning in birds and people, Jarvis wants to see if he can start manipulating the genes with an eye to repairing damaged ones.

Ancient Biology

Another revelation is the relatively rapid rate at which birds evolved compared with their crocodilian relatives, which have remained essentially unchanged for over 100 million years.

By comparing the


discretion in such matters, we find no error in denying the award of attorneys' fees.
For the foregoing reasons, we affirm the judgment of the trial court.
STEPHAN, P.J., and PUDLOWSKI, J., concur.
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- \frac{1}{4}{\left\langle k \right\rangle
^3}\left( {\left\langle {{k^{ - 1}}} \right\rangle  - {{\left\langle
k \right\rangle }^{ - 1}}} \right)\Delta {\lambda ^2}.\label{e20}\end{aligned}$$ Since $\left\langle {{k^{ - 1}}} \right\rangle  > {\left\langle k
\right\rangle ^{ - 1}}$ for any degree inhomogeneous networks in terms of Jensen’s inequality, $\Delta \rho^{opt}<0$ and thus $\rho$ will be reduced. The corresponding optimal allocation $\mu_k=\mu_k^*+\Delta \mu_k$ with $$\begin{aligned}
\Delta {\mu _k} = \frac{\mu }{2}\left\langle k \right\rangle \lambda
 \left( {\left\langle k \right\rangle  - k} \right) \Delta \lambda
\simeq  \frac{\mu }{2} \left( {\left\langle k \right\rangle-k}
\right)\Delta \lambda.\label{e21}\end{aligned}$$ This implies that as $\lambda$ is increased from $\lambda_c^{opt}$, the curing rates of the nodes with degrees less than the average degree will be increased, while the curing rates of the nodes with degrees larger than the average degree will be decreased. The amplitudeand BA networks (b) with equal $N=1000$ and $\left\langle k \right\rangle=4$. The solid lines correspond to the results from the optimal SIS model, the dotted line to the results of the standard SIS model, and the dashed line to the SIS model with $\mu_i=\mu_i^*$. The squares correspond to the results from SA. \[fig1\]](fig1.eps){width="1.0\columnwidth"}

Figure \[fig1\] shows the optimized results of $\rho$ as a function $\lambda$ (solid line) in Erdös-Rényi (ER) random networks (a) and Barabási-Albert scale-free networks (b) with equal network size $N=1000$ and average degree $\left\langle k
\right\rangle=4$. For comparison, we also show the results of the standard SIS model (dotted line) and of the SIS model with the curing rates $\mu_i=\mu_i^*$ (dashed line). As expected by the theoretical prediction, the epidemic threshold of the optimal SIS model $\lambda_c^{opt}=1/\left\langle


(e.g., $\mu_i=\mu$ for all $i$). Then, we randomly choose two distinct nodes, say $i$ and $j$, and try to make the changes $\mu_i \leftarrow \mu_i +\delta$ and $\mu_j \leftarrow \mu_j -\delta$ with the standard Metropolis probability $\min(1, e^{-\beta_{SA}\Delta\mathcal {E}})$, where $\delta$ is randomly chosen between $-\mu_i$ and $\mu_i+\mu_j$ to guarantee the curing rate is always not less than zero. $\beta_{SA}$ is the inverse temperature of SA which slowly increases from $10^{-2}$ to $10^{4}$ via an annealing protocol. $\Delta \mathcal
{E}$ is the change of the energy function $\mathcal {E}$ due the change of $\mu_i$ and $\mu_j$, We tested several different annealing protocols and we adopted one in which the inverse temperature of SA $\beta_{SA}$ is updated by $\beta_{SA} \leftarrow 1.01 \beta_{SA}$ after each $N$ attempts for updating $\{\mu_i\}$. TheSA results are also shown in Fig.1 (square dots), which agree with the theoretical prediction.

![(color online). The optimal allocation of $\{\mu_k\}$ as a function of node degree $k$ for several distinct $\lambda$ in ER random networks (a) and BA scale-free networks (b) with equal $N=1000$ and $\left\langle k \right\rangle=6$. The lines and dots indicate the theoretical and SA results, respectively. \[fig2\]](fig2.EPS){width="1.0\columnwidth"}

In Fig.\[fig2\], we show the optimal allocation of $\{\mu_k\}$ as a function of node degree $k$ for several distinct $\lambda$ in ER random networks (a) and BA scale-free networks (b), in which the theoretical results and the SA ones are indicated by the lines and dots, respectively. For $\lambda \gtrsim \lambda_c^{opt}$, $\mu_k$ increases linearly as $k$ with the slope depending on the distance to the epidemic threshold. The


_k} + \left( {1 - {\Theta ^*}}
\right)\Delta \Theta.$$ In the following we use LMM to minimize $\Delta \rho$ under the constraints $\sum\nolimits_k P(k)\Delta \mu_k=0$ and Eq.(\[eq5\]). Note that the first constraint is due to the fixed average curing rate, and the second one is the requirement of the HMF dynamics. Utilizing Eq.(\[eq8\]) and the two constraints, the Lagrange function can be written as $$\label{eq9}\tag{S9}
\begin{split}
\mathcal {L} =  &- \frac{{{\Theta ^*}}}{\beta }\sum\limits_k
{\frac{{P(k)}}{k}} \Delta {\mu _k} + \left( {1 - {\Theta ^*}}
\right)\Delta \Theta  \\&+ \tau \left( { - \Delta \Theta  +
\frac{1}{{{\beta ^2}\left\langle k \right\rangle }}\sum\limits_k
{\frac{{P(k)}}{k}} \Delta \mu _k^2} \right){\kern 1pt}  + \kappa
\sum\limits_k {P(k)} \Delta {\mu _k},
\end{split}$$ where $\tau$ and $\kappa$ are the Lagrange multipliers. Taking the derivative of $\mathcal {L}$ with respect to $\Delta \Theta$ and $\Deltaa man adorned with modesty and eloquence,
and the venerable Master Gerard let summon him from
Amsterdam in Holland to hear the confessions of the
devout, likewise Gerard committed to him the governance
of the Sisters of his House. For awhile he abode
with the first Brothers in the ancient House of Florentius,
and rose up with the others in the morning to recite
the Hours; and when the time for rising came, he awoke
straightway and went forthwith to arouse the other
Brothers, knocking and saying: “Arise, watch
and pray, that ye enter not into temptation.”
Of this thing Master Gerard maketh mention in the
letter which he wrote to the priests at Amsterdam,
what time he besought that John should be sent to
him, for this alacrity did especially please him.


---
author:
- 'Sergey V. Dolgov [^1]'
title: 'TT-GMRES: on solution to a linear system in the structured tensor format'
---

Introduction
============

Solving linear systems arising from problems with many dimensions is a computationally demanding task. Such problems are posed, for example, in quantum chemistry [@meyer-mctdh-book-2009; @lubich-moldyn-2008], financial mathematics [@sloan-quasi-MC-1998; @wang-high-dim-finance-2006] and many others. To work with $d$-dimensional arrays is a challenging problem due to the *curse of dimensionality* [@beylkin-high-2005]: the number of elements of a tensor grows exponentially with the number of dimensions $d$, and so does the complexity to work with fully populated tensors. For $d$ of order tens or hundreds some other approaches are needed, for example, special low-parametric representations or *formats*. As soon as such a format comes with fast linear algebra algorithms, such as additions, Matrix-by-Vector multiplications and scalar\Leftrightarrow h_{j+1,j}=0$.

In the following we will consider the *inexact* GMRES, for which this theorem does not take place.

Role of preconditioners and smoothers {#sec:precs_and_smooths}
=====================================

A well known way to improve the convergence of an iterative method is to use a preconditioner: $$Ax = b \rightarrow MAx = Mb, \quad \mbox{or}~AMy=b,~x=My,$$ which may shrink the spectrum of a matrix to a small interval (for the discretized PDE problems one usually requires a mesh-independent spectral interval), or make clusters of eigenvalues (see [@tee_clustering_1996; @dkot-P2-2011]).

The first formula is called a *left* preconditioner, the second is a *right* one. The main difference of these approaches (at least, for symmetric matrices) is what residual is computed and considered: the first works with $||MAx - Mb||$, i.e. the *preconditioned* residual, the second - with the real