287 – 296.

N. Krog, and K. Larsson *Fett Wissen schaft Technologie/Fat Science Technology* **1990**, *2*, 54 – 57.

P.L. Benitez-Sanchez, M. Leon-Camacho, R. Aparicio *Eur. Food. Technol.* **2003**, *270*, 13 – 19.

M.Goto, K.Kozawa, and T.Uchida *Bull. Chem. Soc. Jpn.* **1988**, *61*, 1413 – 1436.

J.R. Dyer *Prentice-Hall Inc.* **1969**, 36 – 37.

[^1]: We gratefully acknowledge S.M. Clarke, I. van Damme and A.R. Tajbakhsh for useful discussions and guidance. The help of D.Y. Chirgadze, in obtaining the SAXS X-ray data is gratefully appreciated. This work has been supported by Mars U.K.
hand scalers only. SEM revealed that root surfaces planed in situ by hand-scaling combined with APAD were smoother than those root-planed using hand scalers alone. The control tooth surface was as smooth as those submitted to combined root planing. The clinical study showed that sites submitted to combined root planing displayed enhanced attachment level gain and pocket reduction. These results, associated with the shortened instrumentation time, suggest APAD as a useful instrument for root planing during flap surgery.


I’m happy to debate whether or not table tennis is an art form. But for me the art in the above video is the storytelling itself. This piece has exceptional visuals, wonderful interviewees and a sense of humor. Now why don’t we have more reporting like this on TV?directory as your Haskell file:
{-# LANGUAGE QuasiQuotes #-}
{-# LANGUAGE OverloadedStrings #-}
{-# LANGUAGE TemplateHaskell #-}
import Text.Blaze.Html.Renderer.String (renderHtml)
import Text.Blaze.Html
import Text.Hamlet

-- | The main template
renderTemplate :: String -> String
renderTemplate testVariable = renderHtml ( $(shamletFile "mypage.hamlet") )

main = do
    putStrLn $ renderTemplate "foobar"

When executed, it prints:
<!DOCTYPE html>

This is a test

Value of test variable: foobar

Note that in your application you might need to use either shamletFile, xshamletFile, hamletFile or ihamletFile. See the Hackage documentation and the Yesod book on Shakespearean templates for information on when to use any of those.


survival for 6 days in a murine model without the loss of overall immune responsiveness \[[@R17]\]. However, despite these promising results, the use of magnetic or latex beads as an acellular scaffold may evoke concerns regarding biosafety and organ toxicity *in vivo.* Therefore, a biodegradable, non-toxic, and biocompatible platform should be further developed.

Polylactic-co-glycolic acid (PLGA) is a biocompatible and biodegradable polymer that has been approved by the United States Food and Drug Administration (FDA) and has been widely used to deliver proteins, small molecule drugs, and other macromolecules in research and clinical settings \[[@R18], [@R19]\]. In this report, we investigated whether PLGA polyesters could covalently load antigen and monoclonal antibody (mAb) in order to generate killer microparticles (MPs) that could deplete antigen-specific T cells. PLGA MPs with aPLGA MPs\
Representative SEM image **A.**, size distribution **B.**, and zeta potential distribution **C.** of PLGA MPs generated on-site.](oncotarget-07-12176-g001){#F1}

The capacity of PLGA MPs to couple proteins and mAbs {#s2_2}
----------------------------------------------------

To detect whether PLGA MPs were able to load proteins, 5 × 10^6^ MPs were incubated with 1 mL of PBS containing a series of BSA quantities at 4°C overnight with rotation. After centrifugation, retention of the protein in the supernatant was quantified using a Micro BCA Protein Assay. The amount of protein coupled onto the MPs was calculated by subtracting the amount remaining in the supernatant from the original amount in 1 mL of PBS. The maximum amount of protein loaded onto 5 × 10^6^ MPs was approximately 80 μg (data not shown). The MPs were also incubated with a


molecules) in order to generate antigen-specific cytotoxic MPs. OVA antigen-targeted killer MPs could significantly deplete OVA-specific CD8^+^ T cells both *in vitro* and in OT-1 mice in an antigen-specific manner. Moreover, the H-2K^b^ alloantigen-targeted killer MPs were able to eliminate low-frequency alloreactive T cells in bm1 mice and markedly prolong alloskin graft survival. These results demonstrate the therapeutic potential of killer PLGA MPs for allograft rejections and autoimmune disorders.

It is important to note is that this is a preliminary observational study and mechanistic insights are needed. After two injections of killer MPs, not all target T cells in the OT-1 mice were eliminated, and the effects of the depletion persisted for only 4 days. The incomplete effect may have been due to an insufficient dosage, an inappropriate ratioA85-1), and FITC-labeled mouse anti-Armenian and Syrian hamster IgG mAb (clone G192-1) were purchased from BD Biosciences (Franklin Lakes, NJ, USA). PE-labeled anti-mouse CD4 (clone GK1.5), FITC-labeled anti-mouse CD8a (clone 53-6.7), APC-labeled anti-mouse CD3e (clone 145-2C11), and PE-labeled anti-mouse Vα2 TCR were purchased from eBioscience (San Diego, CA, USA). Polyethylenimine (PEI, 1,800 Da), N-hydroxysuccinimide (NHS, 98%) and N-(3-dimethylaminopropyl)-N- ethylcarbodiimide hydrochloride crystalline (EDC, 99%) were all obtained from Sigma-Aldrich. The Micro BCA Protein Assay kit was purchased from Thermo Fisher Scientific (Waltham, MA, USA). The OVA~257-264~ (SIINFEKL) and TRP2~180-188~ (SVYDFFVWL) peptides were purchased from China Peptides Co. (Shanghai, China), and the purity of each peptide was \> 95%.

Mice {#s4_2}
----

C57BL/6 (H-2K^b^) mice were purchased from the Comparative Medicine Center of Yangzhou University (Yangzhou, Jiangsu, China). Transgenic OT-1 mice were kindly


log-rank comparison of the groups was used to calculate the P values. *P* values \< 0.05 were considered significant.

SUPPLEMENTARY MATERIAL FIGURES {#s5}
==============================

This work was supported by the National Natural Science Foundation of China (Grant No. 81172823 and 81372448), Science and Technology Support Program of Jiangsu Province (Grant No. BE2012739); Fundamental Research Funds for the Central Universities of China and the Post-graduate Research & Innovation Program of Jiangsu province (Grant No. KYLX-0194). The authors thank Dr. Hua Tang (Tai Shan Medical College, Shandong, China) for providing the transgenic OT-1 mouse strain.

**CONFLICTS OF INTEREST**

The authors declare that there are no potential conflicts of interest.
 lst = []
        for num,layer in self.num2layer.iteritems():
            if layer in self.layer2num and self.layer2num[layer] == num:
                dir = "<->"
            else:
                dir = " ->"
            lst.append((num,"%#6x %s %-20s (%s)" % (num,dir,layer.__name__,layer.name)))
        for layer,num in self.layer2num.iteritems():
            if num not in self.num2layer or


Los Angeles (CNN) -- A task force made up of local and federal law enforcement agencies is actively pursuing leads into the 1997 slaying of hip hop artist Christopher Wallace, better known as Biggie Smalls or Notorious B.I.G., according to two sources familiar with the investigation.

According to one law enforcement source, the investigation into the 13-year-old unsolved case was "reinvigorated" months ago as a result of new information, but the source would not elaborate further because of the ongoing investigation that includes the Los Angeles Police Department, L.A. County District Attorney's Office and the FBI.

On March 9, 1997, Wallace, 24, was shot and killed while riding in a Suburban that was driving away from a music industry party at the Petersen Automotive Museum in Los Angeles.

Los Angeles policeVehicle

2010 BMW 3 Series 328i 4dr Sedan (3.0L 6cyl 6M)

Review

I was excited to find that BMW offers a diesel version of the 3 series. I had a 325i and it was running high on miles and decided it was time to change. I found the 335d affordable since they offer an eco credit discount which does help a lot. The car is smooth like my old 325i (2006). The updated I Drive also works great. The best part, well two of the greatest thing about this car are fuel economy which gives me 36 mpg on the freeway and at times I've seen it average more than 36 on the freeway while going 80 mph. The other great thing is the acceleration. 0-60 is fast but going from


density $\rho=N/V$. Interestingly, the DQPT is of second order nature without the RWA, while it is first order if the RWA has been imposed [@1st]. The corrections due to the RWA to various physical observables have been considered [@hioe; @orszag].

More detailed analysis about miscellaneous aspects of the DQPT have been presented in numerous publications. Especially various extensions [@ext; @onePT] as well as approximate methods [@approx] concerning the DQPT has been outlined. Recently, C. Emary and T. Brandes applied the algebraic Holstein-Primakoff boson representation on the DM. The method turned out to be very powerful and have since then been applied frequently to the DM [@alg].

Despite the numerous publications on the DQPT, the existence of this phase transition was widely discussed. If the two-level atoms in the DM correspondatomic density. A natural consequence of the coupled system considered here is that the motional state of the atoms are entangled with the internal state. Thus, the phases (normal and superradiant) are intrinsically different from the ones of the regular DM. The regular DQPT derives from a competition between the free field energy and the interaction atom-field energy. While the free field is minimized by vacuum, the interaction energy decreases with an increasing field intensity. In the present model does the kinetic energy contribute to the total energy. It is thus an interplay between three terms; free field, atom-field interaction (containing the bare internal atomic energies), and motional energies. This is not so evident from the free energy per particle (\[phi1\]), where the kinetic energy is hidden in


the second term. To illuminate the importance of the atomic motion we study the atomic inversion $W$ defined as the probability for a single atom to be in its excited state $|e\rangle$ minus the probability for it to be in the ground state $|g\rangle$. Once the adiabatic approximation has been imposed we are left with a single internal state; the lower adiabatic state $|-\rangle_{ad}=\sin\theta|e\rangle+\cos\theta|g\rangle$. In particular, the angle $\tan2\theta=2g(\hat{x})\sqrt{\rho_0}\alpha/\Omega\sqrt{N}$ depends on the spatial coordinate and the inversion becomes $$\label{atinv}
W\equiv\mathrm{Tr}\left[\hat{\sigma}_z\rho_{at}(x)\right]=\int dx\left(\sin^2\theta-\cos^2\theta\right)\rho_{at}(x).$$ The above equation clarifies that the atomic motion enters the problem in a non-trivial way. It also shows how the internal atomic properties are taken care of even though in the adiabatic approximation the system properties derives from a single internal state $|-\rangle_{ad}$. We have numerically verified the{#sec4}
===========================

In the previous section we studied how the DQPT was modified due to motion of the atoms in a finite potential well, assuming the atomic motion to be frozen out in the longitudinal and one transverse direction. Here we instead assume the atoms to move freely along the center axis of the Fabry-Perot cavity while tightly bound in the transverse directions.

The corresponding single atom Hamiltonian (\[oneatomham\]) reads $$\label{jonham}
h(\alpha)=\frac{\hat{p}^2}{2m}+\frac{\hbar\Omega}{2}\hat{\sigma}^z+\hbar\frac{\lambda\cos(\mu\hat{x})\sqrt{\rho_0}}{\sqrt{N}}\left(\alpha\hat{\sigma}^++\alpha^*\hat{\sigma}^-\right),$$ where $\mu$ is the scaled photon wave number which will be set to unity hereafter, $\mu=1$. This Hamiltonian, with the field still quantized, has been considered in several papers, see for example [@effmass]. Normally $L\gg 2\pi$, where $L$ is the cavity length, so neglecting boundary effects is not a crude approximation [@effmass]. The Hamiltonian is of the form of a


range of parameters $\omega$ and $\lambda$, but there also exist parameter regimes where no QPT occurs for zero temperature.

Like in the previous section the nature of the PTs is studied by introducing the scaled field intensity $I$ maximizing $f_2(y)$. It is found that the QPT’s are of second order character in all cases.

Conclusions {#sec5}
===========

In this work we have studied a new regime in the DM. The atoms are assumed trapped by the cavity field itself and ultracold such that their center-of-mass kinetic energy is of the order of the atom-field interaction. This calls for a full quantum mechanical treatment of the atomic motion and at the same time take into account for spatial mode variations. The analysis is motivated from our earlier findings, where we demonstrated that atomicRitter, T. Bourdel, M. Köhn, and T. Esslinger, Nature [**450**]{}, 268 (2007)\
P. Truetlein, D. Hunger, S. Camerer, T. Hänsch, and J. Reichel, Phys. Rev. Lett. [**99**]{}, 140403 (2007)\
Y. Colombe, T. Steinmetz, G. Dubois, F. Linke, D. Hunger, and J. Reichel, Nature [**450**]{}, 272 (2007)\
F. Brennecke, S. Ritter, T. Donner, and T. Esslinger, Science [**322**]{}, 235 (2008).

C. Machler and H. Ritsch, Phys. Rev. Lett. [**95**]{}, 260401 (2005).

M. Lewenstein, A. Kubasiak, J. Larson, C. Menotti, G. Morigi, K. Osterloh, A. Sanpera, in *Atomic Physics 20*, ed. by C.F. Roos, H. Häffner, and R. Blatt, (AIP Proceedings, Melville, 2006), **869**, pp. 201-211; J. Larson, B. Damski, G. Morigi, and M. Lewenstein, Phys. Rev. Lett. [**100**]{}, 050401 (2008); J. Larson, S. Fernandez-Vidal, G. Morigi, and M. Lewenstein, New J. Phys. [**10**]{}, 045002


In an interview published last year, an exasperated Danish asked our leaders: “You want to make India a Hindu country? Would you kill all the Muslims or turn them out of the country? Please tell us to what extent you would go to finish Muslims?”

AD

He added: “I’m very uneasy. I have a feeling that if the BJP comes back then something big will happen. I cannot say what it is. I feel as if something will break in our country and we will not be able to fix it.”

AD

Danish’s fear permeates life for all Muslims in India. In recent years, we have seen an explosion of ethnic and religious mob violence. This year’s election campaign is fanning the flames.

On April 11, the first day of voting, the rulingno one cared.

They noticed, all right, as he plowed through their ranks. In fact, some of them were actually applauding as he passed. As if to say, "Yeah! HIT THE ROAD, MOTHERFUCKER!"

It was the first and only applause he'd gotten all night.

Anger got him off the stage, but shame took him the rest of the way out the door. That, and the eyes that followed him, mocking, as if suddenly _he_ was the asshole.

Then Nando laughed into the other mic and yelled, "Yeah? _You_ WALK _home,_ pendejo!"

That was when the fear set in.

Tommy slammed the door behind him, and the volume cut abruptly in half. But the applause roughly doubled, and the band kicked in hard, as if to signal they were _glad_ that he was gone, like


itself, as if everything out here was just a little bit radioactive.

The ugly, blank buildings that crowded the buckled sidewalk were colorless brick boxes, anonymous or scabbed with illegible, ancient signage, most of the doorways boarded or bricked up. There was no sign of anyone else on the street, for blocks in either direction.

_You could die out here._

The farther he got from the party, the quieter and more unearthly it became, with just the echoing buzz of freeway traffic bouncing off the walls from far away. As desolate as anywhere in New Mexico, this sub-basement of Los Angeles only drove home the emptiness of the rest of it.

Packed with people who wouldn't piss on you if you caught fire, L.A. was easily the loneliest place he'd ever known.

Skippingcool. Are you feeling me?"

"No problem . . . sir." Rory knew what the role required, but he wasn't wearing a chauffeur's hat, and he wasn't angling for a fat tip from this smug, lanky kid, who might be a first-round NBA draft pick if he bothered to work out.

The vibe he got off this kid had Rory despising him and his hoochie harem before he closed the door and got behind the wheel, trying to ignore the mocha-colored virago beside him. The kid and his girlfriends were so high they couldn't feel their faces, and it made Rory a lot madder than it should have. Because underneath—and in spite of everything he had to be grateful for—he was jealous of them.

Those days were long gone, and he


or black. Every bloodshot eye that rolled up to take her in registered only the slightest pulse of interest as she tore through their midst, screaming, "Get out of here! _Apurate!_ These crazy gringo motherfuckers are poisoning _la gente!"_

They just stared at her. The doors flew open behind her and the nurse she stabbed shouted, "Stop her! She's a thief!"

Nobody moved. Whatever they were doing to the people in the ER, they hadn't got around to these people, yet.

Or so she thought.

Someone's leg shot out and tripped her. She tumbled into a grandmother who threw out her arms and caught Trixie by her ponytail.

Her hacking cough blasted spit and phlegm in Trixie's face, but she couldn't bring herself to hit the old woman, who was at least eighty.

_"Bedesperate measures behind closed doors. The only way to give dying people choice and control at the end of life, while also best protecting vulnerable people, is through an assisted dying law with upfront safeguards. Sadly people will continue to suffer in search of the death that they want as long as this cruel law exists, a law that the overwhelming majority of the public want to change.”

Dignity in Dying
Dignity in Dying campaigns for greater choice, control and access to services at the end of life. It advocates providing terminally ill adults with the option of an assisted death, within strict legal safeguards, and for universal access to high quality end-of-life care.


to the right?

I'm not sure what you mean, but I'll try to explain them. They are just the default icons for the user folders in Windows 7. The smaller icon images in the folder are to represent what the folder is for.

For example:

blue down arrow for "Downloads"

Windows Photo Viewer icon for "My Pictures"

Same "Favorites" star used in Internet Explorer Favorites

The blue curved arrow pointing up and to the right for "Links" is like a "shortcut arrow" since links are basically shortcuts.

Well I went through the instructions and my machine appears to be operating in something that appears to be like the default configuration that was setup when I installed Windows 7. There is one exception (problem) however. When I right click on Libraries I get an error messagenew PC, but for the first time I've installed a SSD to hold Win7 while all my data (in theory) will be held on my data drive (2 TB Hard Disk).
I've redirected most of my user folders just fine, "My Documents", My Music, Downloads etc. however when I installed my...

General Discussion

Viewing the documents library displays my documents folderOk, I need some help..
I know that the documents library is a "library" and when I save anything there it really saves the file to the default location(my documents).
I teach a basic PC course usage course to seniors and some of the PCs are now listing the "My Documents" and the "Public"...

Customization

Contents in My Documents are both in My Documents and My Music.I can't say when this started to happen, but


= 0.5$). Not taking either effects into account causes about 0.1 change in the derived matter density (compare results using methods A and D). As we can see, the temperature function is very sensitive to CDM model parameters if one uses a full CDM treatment, and thus a precise determination of the matter density is possible if the Hubble constant is known. We should keep in mind, however, that the normalization of the $M(T)$ relation, for example, causes much larger error in determining $\Omega_m$. Since this method does not allow us to separate the density parameter from the Hubble constant, the result is a best fit function of the two. We can make use of the results from the power law approximation which gives the best fit density  /* years - [1980..2044] */
} tm_unz;

/* unz_global_info structure contain global data about the ZIPfile
   These data comes from the end of central dir */
typedef struct unz_global_info_s
{
    uLong number_entry;         /* total number of entries in
                       the central dir on this disk */
    uLong size_comment;         /* size of the global comment of the zipfile */
} unz_global_info;

/* unz_file_info contain information about a file in the zipfile */
typedef struct unz_file_info_s
{
    uLong version;


           int* level,
                                           int raw,
                                           const char* password));
/*
  Same than unzOpenCurrentFile, but open for read raw the file (not uncompress)
    if raw==1
  *method will receive method of compression, *levelwill receive level of
     compression
  note : you can set level parameter as NULL (if you did not want known level,
         but you CANNOT set method parameter as NULL
*/

extern int ZEXPORT unzCloseCurrentFile OF((unzFile file));
/*
  Close the file in zip opened with unzOpenCurrentFile
  Return UNZ_CRCERROR if all the file was read but the CRC is not good
*/

extern int ZEXPORT unzReadCurrentFile OF((unzFile file,
                      voidp buf,
                      unsigned len));
/*
  Read bytes from the current


has an advantage. Biden is slightly more competitive against Bush, and he's equally competitive against Trump. Clinton beats Rubio by a slightly better margin than Biden and does significantly better than Sanders.

Quinnipiac also reports that Biden's general matchup numbers are a little better than that of Clinton's, and that the vice president "has the best favorability rating among top Republican and Democratic candidates." But Clinton still leads the Democratic field at 45%, with 22% going to Sanders and 18% going to Biden. This number, however, represents a drop for her from 55% in late July.

It's early, most of the numbers are within the margin of error, and it's only one poll. Plus, this group is only a component of a successful Democratic campaign - we need a broad     float_minheap_array_t *res,
                 bool init_finalize_heap = true) const;

    /// Symmetric Distance Table
    std::vector<float> sdc_table;

    // intitialize the SDC table from the centroids
    void compute_sdc_table ();

    void search_sdc (const uint8_t * qcodes,
                     size_t nq,
                     const uint8_t * bcodes,


your instance of Uber.
Point 2 is impossible. The server is not allowed to provide you info about the instances of Servlet it has created. The method to obtain these, ServletContext#getServlet, is deprecated. Also, the application server may use a single instance or multiple instances of a Servlet, the server will decide the behavior at runtime.
Since we don't exactly know your purposes on knowing the instances of Servlets and what to do with them, we cannot provide more help.
Still, in point 1, since you create the instance of Uber, you can store it as an attribute in ServletContext, and then retrieve it in each servlet using HttpServletRequest#getServletContext.

From your comment, it looks like you want/need to implement Front Controller. For that, it will be better to use a single servletme" "Bree, what's got into you?" "I have the same recipe for English plum pudding" "It takes six hours to prepare" "How would you have time to make all this and everything else that we ate today" "This's not the pudding of an honest woman" "FBI, open up" "What on earth... looking for a Maxine Bennett" "I'm Maxine" "We have a warrant." "This is the premier's mail" "A warrant?" "I'm in the middle of a luncheon" "Over here" "Found her" "Maxine Bennett, you are under arrest, for involuntary servitude" "Is this the woman who locked you up?" "Bree, what's going on?" "Well, I'm not sure, but I think Maxine had a slave" "I can't believe it, I just can't believe it" "But Bree could you see, for her


it sound like we are angry, we are not angry" "I'm a little angry" "Can we talk about this later?" "I have ice-cream in here" "Bree, could this flip-flop have something to do with the fact that Daniel is dating Matthew?" "Yeah, that would get her" "Who told you that?" " Mrs. McClosky- she saw them making out in the park" " Eddie!" " What?" "Can't you sugar-coat a little?" "I did, he had his hand down her shirt" "Bree, we know that you have a good reason for wanting Betty to hang out with us" "We just wondered if you could clue us in a little" "When it comes to Betty Applewhite, I know what I'm doing and you two are just gonna have to trust meGary Grantham your future ex-husband." " Wow, nice to meet you." " Hi." "Okay, listen, um, I've got to meet a client." "I've got to go, so just talk amongst yourselves, and you two make a very handsome couple." "Oh." "Yeah." "Uh,- hi.- hi." "So do you wanna get married on Wednesday?" "'Cause Thursday and Friday I'm out of town." "Oh!" "Oh, yeah." "Sure, that's--Wednesday's great." "I'm--I'm just curious... how did Eddie convince you to do this so quickly?" "Well, she explained your situation to me." "I'm sort of in need of a fake bride myself, so I figured, what the heck?" "Why would you need a fake bride?" "Uh, I'm gay, and I've never come out to my mother." " Really?" " Yeah." "At first, I just


didn't want to upset her." "Then she got older, she got emphysema and diverticulitis, and I started thinking, if I just kept my mouth shut, then one day nature would take its course and we could avoid what is sure to be a very ugly scene." "So what changed?" "She told me at her81st birthday party last month, the only reason she's hanging on is to see me get married." "Oh." "Oh, so by marrying me... yeah, I'd get my inheritance that much sooner." "No, but mostly, I wanna make sure she's happy." "well, you seem very nice, Susan." "Uh, it will be a pleasure being married to you." "Uh, likewise." "here, you can finish the rest of the fries." "Here's your mail and your pills." "Ugh." "Moretoilet?" "Yeah!" "For the Galveston jewelers account." "I don't care!" "You're not gonna do this!" "Look, Lynette, you're the one who told me to find a way to click with ed." "Well, now we've got our thing, and it's paying off for me!" "That's because ed gets off on humiliating you." "Please, don't do this!" "We're waiting, scavo!" "This is my moment." "so, caleb, besides your mother and brother, does anybody else know that you're here?" "No." "You're pretty." "thank you." "That's very sweet." "So where have you been living this whole time?" "Upstairs?" "No." "I just moved upstairs." "My room's downstairs." "Downstairs?" "In the basement." "You wanna see it?" "Caleb, have you been down here all these months?" "Yeah." "Did your mother make you wear those?" "Most


"Oh, do you have a thing to play music?" "I had Steven burn a little wedding mix for us,." "for ambience" "Sure, just, um, give me a sec" "do you have a problem?" "You said she was sick." "She is." "She has a wandering spleen." "It sounds nothing like cancer." "It doesn't even sound real." "Well, it is." "I-I could die." "You look fine to me, honey." "Don't do this." "I have asked you six times to fly with me to Holland to get married, and you always have some la me excuse." "But the second some chick with a silly disease comes along, well, you drop everything and head for a chapel." "Oh,no,it's a serious illness." "See, it just sounds silly 'cause of the word "spleen."" "Whatplay anymore." "No,no,no, I can't." "I can't." "If I back down now, he'll see it as a sign of weakness." "Look, this is the way that guys do business." "But-- so you called it." "He made me his bitch." "Come on." "Here you go." "Oh." "You know, ed, I've been thinking." "We've had a lot of fun and games around here lately, but maybe it's time to set a slightly more professional tone in the office." "Oh, I get it." "Somebody went running to mommy, didn't he?" "Huh?" "What?" "Tom loses a few bets, so he tries to get his wife to make me back off?" "Oh, this is so alpha tau." "I am gonna make him pay." "No." "No, you're not gonna make him pay." "You are


I think you're gonna need a little help getting through it." "his name's Zach young." "He lives with his father." "Mother committed suicide about a year ago." "How did he end up with these people?" "How do you think?" "Deirdre was strung out, noah." "She gave him up." "I wanna see this boy." "Well, he's got a new family now." "I can't just snap my fingers and get him in here." "Maybe not, but I can snap my fingers, and detective Sullivan can make it happen." " You don't wanna do that." " No?" "Is that really the way you wanna meet him-- have that thug drag him in here so grandpa can give him a hug?" "Fine." "You bring him." "I'll give you two days." "As you[Strabismus determined by anatomical changes in the extrinsic ocular muscles].
The anatomical primitive strabismus is prenatal and its characteristic is the loose in the elasticity of the muscles of the surrounding tissues. The cause is the deficit of embryogenesis, originating in the first two months of pregnancy. They are presented the clinical cases of anatomical strabismus, investigated and treated in the Ophthalmological Clinic during 10 years, the surgical techniques used and the postoperative functional and obstetrical results the ocular disturbances are intense and the debut is early. The surgery involves both eyes and the results depend on the clinical form, the restant ocular motility and the degree of fibrosis of the affected muscle.


2016-05-05T16:50:00-04:00
> typeof(dates)
[1] "integer"
> as.POSIXct(dates[1])
[1] "2016-05-05 EDT"
> as.character(dates[1])
[1] "2016-05-05T16:46:21-04:00"
> as.POSIXct(as.character(dates[1]))
[1] "2016-05-05 EDT"

A:

You can use as.POSIXct with the tz argument to convert the timestamps with the right level of control.
If the timezones are all UTC-04:00 and that is your local timezone, you can use:
dates = as.POSIXct(dates, format="%Y-%m-%dT%H:%M:%S", tz=Sys.timezone())

If they are all UTC-04:00 and that is not your local timezone, but you know the exact location, then you can specify the appropriate timezone from the tz database:
dates = as.POSIXct(dates, format="%Y-%m-%dT%H:%M:%S", tz="America/Port_of_Spain")

Alternatively, you can use a generic GMT-4 timezone:
dates = as.POSIXct(dates, format="%Y-%m-%dT%H:%M:%S", tz="Etc/GMT-4")

[EDIT: With thanks to Roland for his comment below. I originally used strptime, which uses the same syntax, but returns a POSIXlt object.]

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Ricki was rushed to Queen’s Hospital in Rom Valley Way where he was placed on an antibiotics drip.

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Israel's Netanyahu denies wrongdoing ahead of investigation Published duration 30 December 2016

image copyright Getty Images image caption Mr Netanyahu said all scandals in the past have turned out to be "baseless"

Israel's Prime Minister Benjamin Netanyahu says a probe into alleged wrongdoing will uncover no evidence against him.

Local media reports suggest that the nation's attorney general is set to launch an investigation into the prime minister's actions.

Israeli media have reported allegations that he has received significant gifts or "favours" from businessmen.

But Mr Netanyahu denies the claims, saying there is nothing to uncover.

He said rumours of impropriety will turn out to be as false as previous claims against him have been.

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Asked whether the White House has the support of four publicly undecided senators on the confirmation of Supreme Court nominee Brett Kavanaugh, deputy press secretary Raj Shah replied, “At this moment, I cannot say for certain that we do.” | Win McNamee/Getty Images White House White House spokesman: Can't say 'for certain' that we have the votes for Kavanaugh

White House deputy press secretary Raj Shah said Friday that he couldn’t say “for certain” that President Donald Trump has enough Senate support to confirm Supreme Court nominee Brett Kavanaugh, though he said “we’re getting there” on securing votes.

Shah’s statement came one day after Kavanaugh spent hours Thursday vigorously denying an allegation that he sexually assualted professor Christine Blasey Ford while the two were in high school. After hearing fromkids are healthy and happy (for the most part) and for now, I'll keep doing my best to do my best.

About Me

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with large bellies and small bodies walk among the crowds at the 10:30 a.m. lunch on Wednesday. Out of more than 600 students, there are always about a dozen or so girls pregnant or with newborns, teachers say. More young men than that are fathers.

"Put shoes on," said Maria Anderson, an assistant principal at Brainerd, to one pregnant student wearing open-toed shoes in the hallway.

"My feet be swollen," she said, a little whine in her voice. Anderson lets her pass.

"They grow up quick. They grow up quick," said David Rogers, another assistant principal, who watches the kids shuffle out of the cafeteria.

The school resource officers, wearing a thick belt of guns, handcuffs and Tasers, laugh with students in the hallway. Deputy Marty Ray teased one student about when"I think they look at me like their grandmother. They are good kids."

Senior portraits and tokens of student accomplishments cover a bulletin board in Joynes' office. But one corner is pinned with the funeral programs of several students he has lost.

Joynes had mentored one of them at Brainerd. He was a gang member who was on track to graduate. Joynes said he was one of the few he confronted and actually reached. He remembers the teen bragging about his improving grades not long before he was shot in the head and back.

He wants to reach teens sooner, before they build the relationships that could kill them. He wants to tell them to stop having sex if they don't want to be parents. And if they father a child,


he wants them to own up to it. He wants to tell them that gangs will use them up and spit them out. He wants to tell them that if they look like thugs people will be afraid of them.

Above all, he wants to tell them that being black doesn't mean what they think it means. And dressing professionally, cleaning up their speech and focusing on school doesn't mean they are "acting white."

"What should have happened when you were little: your daddy, your momma, your granny should have yanked your pants up for you," he told the group of boys on Friday. "Cussing and sagging is not normal to the rest of the world. It might be in your small community."

Earlier this school year, Joynes gave copies ofthey weren't that shaken by Principal Joynes' plea.

"Maybe a couple people will change. Five people, maybe 10," said Dexter Jones, 17.

"What people say in school doesn't have a big influence," said Jeremy McGhee, 16. "It's really the community that has the influence."

For Joynes, the verdict is still out. He's doing his part.

On the Monday after spring break, he'll see whether the kids will do theirs.

Gallery: Life changersLocals share memories of the pieces of tech that changed everything for them


Lawyer: Snowden Can Stay 3 More Years in Russia

Former NSA systems analyst Edward Snowden, who is wanted by the U.S. for leaking details about once-secret surveillance programs, has been granted permission to stay in Russia for three more years, his lawyer said Thursday.Operators, Inc., 701 S.W.2d 238, 241-42 (Tex.
1985), cert. denied, 476 U.S. 1159, 106 S.Ct. 2279, 90 L.Ed.2d 721 (1986).  The mere fact that a trial
judge has decided a matter within his discretionary authority in a different manner than we would
does not constitute an abuse of discretion.  See id. at 242.
ALLEGED DEFICIENCIES OF THE REPORT
	We begin by addressing the individual deficiencies raised by Dr. Grindstaff.  While he lists
ten issues for review, they may be answered in three segments:  (1) Was Dr. Cartwright qualified to
render an expert opinion regarding the care provided by Dr. Grindstaff?; (2) Did his report
adequately set forth the applicable standard of care?; and (3) Did his report adequately address
causation?  If these questions are answered in the affirmative, then the report meets


the statutory
requirements of the Act as contained in Chapter 74 of the Texas Civil Practices and Remedies Code.
Qualifications
	First, Dr. Grindstaff contends Dr. Cartwright's report is deficient because Dr. Cartwright is
not a podiatrist and he does not articulate how he is qualified to render an opinion on the standard
of care applicable to a podiatrist.  Dr. Grindstaff also contends Dr. Cartwright's curriculum vitae
fails to indicate his training involving proper treatment for diseases of the feet.
	A health care liability claim is defined as a cause of action against a health care provider or
physician for treatment, lack of treatment, or other claimed departure from accepted standards of
medical care, or health care, or safety or professional or administrative services directly related to
health care, which proximately results in injury to orof care.  See Section 74.351(a).  Identification of the standard of care is critical since
"[w]hether a defendant breached his or her duty to a patient cannot be determined absent specific
information about what the defendant should have done differently."  American Transitional Care
Centers of Texas, Inc. v. Palacios, 46 S.W.3d 873, 880 (Tex. 2001). "While a 'fair summary' is
something less than a full statement of the applicable standard of care and how it was breached, even
a fair summary must set out what care was expected, but not given."  Id., citing Palacios v. American
Transitional Care Centers of Texas, Inc., 4 S.W.3d 857, 865 (Tex.App.--Houston [1st Dist.]
1999)(Taft, J. dissenting).
	Dr. Cartwright's report contains the following opinions:
	 The conservative approach prescribed by Dr. Grindstaff was neither sufficiently
inclusive nor of sufficient


Q:

alternate CSV row deletion

I have a csv file as follows:
gindex
1
1
2
2
3
3
7
7

I printed each element twice by mistake. How can I delete each repeated row and get the following results:
gindex
1
2
3
7

A:

No need for fancy csv handling, if it is really just every second line you want to dismiss, do something like:
with open("csv") as f:
    for i, line in enumerate(f):
         if i % 2 == 0:
             print(line)

baseStorage, active);
                }
            }

            // it was all completed in the recursive calls above
            return;
        }

        if ((reflection.options & EShReflectionBasicArraySuffix) && terminalType->isArray()) {
            name.append(TString("[0]"));
        }

        // Finally, add a full string to the reflection database, and update the array size if


0)
                    topLevelArrayStride = variables.back().arrayStride;
            }

            if ((reflection.options & EShReflectionSeparateBuffers) && terminalType->getBasicType() == EbtAtomicUint)
                reflection.atomicCounterUniformIndices.push_back(uniformIndex);

            variables.back().topLevelArrayStride = topLevelArrayStride;

            if ((reflection.options & EShReflectionAllBlockVariables) && active) {
                    0, 0, base->getQualifier().storage, false);
                        }
                    }
                } else {
                    // otherwise - if we're not using strict array suffix rules, or this isn't a block so we are


    return type.isArray() ? type.getOuterArraySize() : 1;
    }

    TReflection& reflection;
    std::set<const TIntermNode*> processedDerefs;

protected:
    TReflectionTraverser(TReflectionTraverser&);
    TReflectionTraverser& operator=(TReflectionTraverser&);
};

//
// Implement the traversal functions of interest.
//

// To catch dereferenced aggregates that must be reflected.
// This catches them at the highest level possible in the tree.
bool TReflectionTraverser::visitBinary(TVisit /* visit */, TIntermBinary* node)
{
    switch (node->getOp()) {
    case EOpIndexDirect:
    case EOpIndexIndirect:
    case EOpIndexDirectStruct:
        addDereferencedUniform(node);
        break;
    default:
        break;
    }

    // still need to visit everything below,   if (getLocalSize(dim) > 1)
                printf("Local size %s: %d\n", axis[dim], getLocalSize(dim));

        printf("\n");
    }

    // printf("Live names\n");
    // for (TNameToIndex::const_iterator it = nameToIndex.begin(); it != nameToIndex.end(); ++it)
    //    printf("%s: %d\n", it->first.c_str(), it->second);
    // printf("\n");
}

} // end namespace glslang


other interferants showed weak response on the sensor surface (up to 35% quenching of red emission with picolinic and isophthalic acid). The response half-time of DPA was determined based on the exponential decay curve in [Figure 6](#f6-ijms-12-07335){ref-type="fig"}, and DPA showed a response half-time of around 5 min.

The high selectivity of DPA sensing on **2**-**1**.Eu^3+^ is attributed to a higher binding affinity of DPA to Eu^3+^ \[[@b60-ijms-12-07335],[@b61-ijms-12-07335]\] due to its stronger coordination to Eu^3+^ via two carboxylic acid groups and the basic nitrogen atom on its aromatic ring, whereas the other aromatic ligands coordinate to Eu^3+^ via fewer groups. In addition, the carboxylic acid screening in solution was also performed and only DPA selectively displaced **2** after 10 min (data not shown) owing to the much stronger coordination of30 min in the microchip. The self-assembly of the Eu(III)-EDTA conjugate and naphthalene β-diketone resulted in the formation of a highly red luminescent lanthanide system on the microchannel surface via the energy transfer from the antenna to the surface-anchored Eu(III).

3.5. Microfluidic Fluorescent Sensing Experiments
-------------------------------------------------

Different analytes (phosphates such as ATP, ADP, AMP, pyrophosphate, hydrogen phosphate and carboxylic acids such as *o/m/p*-phthalic acids, picolinic acid and dipicolinic acid) in 50 mM HEPES buffer with 50 mM NaCl (pH 7.4) were injected from five inlets with a 1 μL/min flow rate at room temperature at a multiplexed format for turn-off sensing experiments. For these sensing experiments, all phosphates and carboxylic acids were used at 1 mM concentration. For detection sensitivity experiments, an ATP concentration down to 50 μM and a DPA


concentration down to 40 nM was used. The decrease in red emission for each channel in the microchip upon sensing was quantified using a fluorescence microscope using filter R (*λ~em~* = 615 nm), and a narrow band excitation filter (300 nm \< *λ~exc~* \< 400 nm) was used to eliminate direct excitation of analytes such as DPA (*λ~exc~* = 270 nm). The data shown in [Figures 3](#f3-ijms-12-07335){ref-type="fig"} and [6](#f6-ijms-12-07335){ref-type="fig"} were reproduced 5 times on the same chips, and found to be reproducible to within 10%.

4. Conclusions
==============

In conclusion, we have developed a supramolecular sensing platform on a microchip surface that allows the detection of biologically relevant phosphate anions and aromatic carboxylic acids at a multiplexed format. ATP and pyrophosphate among various phosphate anions, and the anthrax biomarker DPA amongvarious aromatic carboxylic acids, showed a strong response to the sensitized Eu^3+^ luminescence-based microchip surface, exhibited by strong quenching of red emission for the anions and DPA in a few to tens of minutes. ATP was sensed by **2**-**1**.Eu^3+^ and showed μM detection sensitivity. Higher detection sensitivity (\~100 nM) was achieved for DPA.

Therefore, as a first demonstration of phosphate and carboxylic acid sensing on the same lanthanide-based surface-receptor platform in a microfluidic chip at a multiplexed format, this study offers a general detection platform for phosphates and carboxylic acids in a single test run with high detection sensitivity and selectivity. From this point of view, this supramolecular surface assisted sensing system in multichannel opens new avenues to yield new classes of surface-based detection devices for biologically relevant ions


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Also make sure that you have a strong reference to the subscribed object held somewhere (this in your subscription code).


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2016

Product Details

2016 BH Bikes RX Team Ultegra

Equally at home at Hoogerheide, Holy Week, and your local cyclocross series, the RX Team Frameset from BH delivers World Cup-level performance. Every tube on this exquisite carbon frame is shaped to optimize efficiency, and the tapered carbon fork provides precise handling and a smooth ride over even the roughest courses. An 386EVO bottom bracket ensures pedaling efficiency, while 'cross-specific features like the shoulder-friendly top tube, ample mud clearance, and maintenance-reducing internal cable routing keep you ready for whatever the course throws at you. A buttery-smooth Shimano Ultegra drivetrain provides reliable, crisp performance to get you up steep walls, while the TRP Spyre disc brakes keep you in control through off camber corners. Rounding out the build areequally and entering the unknown depths through both farmhouse and stone building. Capt. Whipple's belief in the existence of catacombs was absolute, and he took no alternative into consideration when making his plans. He had with him a whistle of great power and shrillness, and did not fear any upsetting or misunderstanding of signals. The final reserve at the landing, of course, was nearly out of the whistle's range; hence would require a special messenger if needed for help. Moses Brown and John Carter went with Capt. Hopkins to the river-bank, while President Manning was detailed with Capt. Mathewson to the stone building. Dr. Bowen, with Ezra Weeden, remained in Capt. Whipple's party which was to storm the farmhouse itself. The attack was to begin as soon as


had now been so perfected that it could be taught successfully. One must be careful about evocations, for the markers of old graves are not always accurate.

Willett and Mr. Ward shivered as they passed from conclusion to conclusion. Things—presences or voices of some sort—could be drawn down from unknown places as well as from the grave, and in this process also one must be careful. Joseph Curwen had indubitably evoked many forbidden things, and as for Charles—what might one think of him? What forces "outside the spheres" had reached him from Joseph Curwen's day and turned his mind on forgotten things? He had been led to find certain directions, and he had used them. He had talked with the man of horror in Prague and stayed long withas the grotesquely weathered stones of the Garden of the Gods in Colorado, or the fantastically symmetrical wind-carved rocks of the Arizona desert. Perhaps we even half thought the sight a mirage like that we had seen the morning before on first approaching those mountains of madness. We must have had some such normal notions to fall back upon as our eyes swept that limitless, tempest-scarred plateau and grasped the almost endless labyrinth of colossal, regular, and geometrically eurhythmic stone masses which reared their crumbled and pitted crests above a glacial sheet not more than forty or fifty feet deep at its thickest, and in places obviously thinner.

The effect of the monstrous sight was indescribable, for some fiendish violation of known natural law seemed certain at the outset.


Danforth's present breakdown. But it had to be; for we could not issue our warning intelligently without the fullest possible information, and the issuance of that warning is a prime necessity. Certain lingering influences in that unknown antarctic world of disordered time and alien natural law make it imperative that further exploration be discouraged.

#  VII.

The full story, so far as deciphered, will shortly appear in an official bulletin of Miskatonic University. Here I shall sketch only the salient high lights in a formless, rambling way. Myth or otherwise, the sculptures told of the coming of those star-headed things to the nascent, lifeless earth out of cosmic space—their coming, and the coming of many other alien entities such as at certain times embark upon spatial pioneering. They seemedMartinique (an island controlled by the French up to 1762, when it was captured by the British); St. Eustatius (an island controlled by the Dutch); Havana (the chief city of Cuba, at this time controlled by the Spanish); and Port Royal (a port on the south coast of Jamaica, controlled by the British).

 The "Royal" (British) troops were on their way to New France (Canada) because of the Seven Years War (or French and Indian War) of 1756-63, in which the British and their colonies in America fought the French and their colonies.

 All these shopkeepers are mentioned in Kimball: James Green (326), Joseph and William Russell (326), Clark and Nightingale (321).

 The old Colony House burned down in 1758 and the new one overlooking North Main Street


cotrimoxazole prophylaxis (CTXp), and if eligible, ART. At the time of the study, the CD4 count threshold for ART eligibility in Uganda was ≤500 cells/mm^3^ [12](#jia225014-bib-0012){ref-type="ref"}.

2.3. Intervention {#jia225014-sec-0009}
-----------------

### 2.3.1. Development {#jia225014-sec-0010}

The intervention was developed based on published evidence indicating that psychosocial factors are common barriers of linkage to HIV care in SSA [13](#jia225014-bib-0013){ref-type="ref"}, [14](#jia225014-bib-0014){ref-type="ref"}, [15](#jia225014-bib-0015){ref-type="ref"}, [16](#jia225014-bib-0016){ref-type="ref"}, [17](#jia225014-bib-0017){ref-type="ref"}, [18](#jia225014-bib-0018){ref-type="ref"}, [19](#jia225014-bib-0019){ref-type="ref"}, [20](#jia225014-bib-0020){ref-type="ref"}, [21](#jia225014-bib-0021){ref-type="ref"}, [22](#jia225014-bib-0022){ref-type="ref"}, [23](#jia225014-bib-0023){ref-type="ref"}, and that counselling can reduce the effects of these barriers [17](#jia225014-bib-0017){ref-type="ref"}, [24](#jia225014-bib-0024){ref-type="ref"}, [25](#jia225014-bib-0025){ref-type="ref"}, [26](#jia225014-bib-0026){ref-type="ref"}, [27](#jia225014-bib-0027){ref-type="ref"}, [28](#jia225014-bib-0028){ref-type="ref"} and may increase linkage [6](#jia225014-bib-0006){ref-type="ref"}, [7](#jia225014-bib-0007){ref-type="ref"}, [9](#jia225014-bib-0009){ref-type="ref"}.

### 2.3.2. Content {#jia225014-sec-0011}

Counselling sessions addressed the following generic points: acceptance of HIV diagnosis, plans to seek care, fear or experience of stigma, importance of HIV status disclosure and availability of psychosocial support for linkage to care; and information about available care services, antiretroviralstudy outcomes. To assess the potential of contamination between trial arms, counsellors asked participants if they had discussed the study with fellow participants from other villages.

For each participant who reported that they linked to care, a field team member visited the clinic to verify whether the participant had indeed been registered for care. Participants whose records could not be found were re‐interviewed to clarify whether they had actually linked or not. Only participants whose records were found were categorized as "linkers". Participants' clinic records were checked to confirm CD4 count testing and receipt of the results, and initiation of CTXp and ART. Adherence to CTXp was measured by self‐reported responses to a question on missed doses. Participants who missed ≤5 of 30 doses in the past month were


might change over time. Therefore, the proportional hazards assumption was examined by splitting follow‐up time into two intervals (0--2 months and \>two months) at a point corresponding with the time of the second counselling session, and testing for an interaction between trial arm and time. Similar methods were used to estimate the effect of the intervention on the proportions that adhered to CTXp, and on the time to obtaining CD4 counts, and ART initiation among HIV‐positive participants, and on the proportion that accepted repeat HCT among HIV‐negative participants.

Analyses based on cluster‐level summaries (Supplementary File) were also performed to check the robustness of the individual‐level analysis, using methods for stratified cluster‐randomized trials [36](#jia225014-bib-0036){ref-type="ref"}. Intervention effects on binary outcomes were measured using prevalence ratios (PR), calculated as the ratio of the            --                  --

IQR, interquartile range.

Socio‐economic status categories were obtained from a wealth index scale based on ownership of household and other properties using principal component analysis.

John Wiley & Sons, Ltd

3.1. Linkage to care {#jia225014-sec-0027}
--------------------

134/302 participants (44.4%) reported to have linked to care but clinic records were found for 127 (42.1%) only. Seven participants whose clinic records could not be found were re‐interviewed; all admitted that they had not linked. Of those confirmed to have linked, 8 (6.3%) had registered with a facility outside of the study area. Linkage to care was higher in the intervention arm compared to the control


aHR=3.27, 95% CI = 1.57--6.81\]. Results from the cluster‐level analysis were consistent with an intervention effect on time to obtaining CD4 counts \[RR = 2.10, 95% CI = 1.14--3.84; aRR = 2.12, 95% CI = 1.22--3.70\].

3.3. ART initiation {#jia225014-sec-0029}
-------------------

Of those enrolled, 90 (29.8% of all participants and 70.9% of those who linked) individuals initiated ART. This included 61 (95.3%) of 64 individuals who had a CD4 count of ≤500 cells/mm^3^, the ART eligibility threshold at the time of the study [12](#jia225014-bib-0012){ref-type="ref"}. Overall, 50 (33.6%) participants initiated ART in the intervention arm *versus* 40 (26.1%) in the control arm \[HR = 1.31 (95% CI = 0.85--2.04)\]. The effect estimate was unchanged after adjusting for age, sex and travel time to the HIV clinic \[aHR = 1.33, 95% CI = 0.85--2.06; Table [3](#jia225014-tbl-0003){ref-type="table-wrap"}\]. There was strong evidence of interaction between trial arm and follow‐up time (*p* = 0.0007). In the first follow‐upsecond counselling visit. Although the two counselling sessions covered similar content, the second session also provided an opportunity to follow‐up on issues identified in the first session as well as address new concerns.

The effect estimates observed in our trial were stronger than those observed in the only other trial that previously investigated the impact of counselling on linkage to care among HIV‐positive persons identified through community‐based HCT (mobile HCT and HBHCT) in SSA [37](#jia225014-bib-0037){ref-type="ref"}. Counselling in that trial increased the proportion of individuals linking to care by 4% only. This was probably due to the already high (89%) level of linkage to care in the standard‐of‐care (referral only) arm of that trial. In contrast, linkage to care in our standard‐of‐care arm was 33%, a figure consistent with that


HBHCT in SSA. The trial was conducted under real‐world conditions in a relatively large geographical area with facilities that provided standard services. Participation and retention rates were high and did not differ by treatment arm thereby reducing risk of selection bias. The cluster‐randomized design further minimized selection bias, and ensured that the risk of contamination between treatment arms, and consequently that of diluting intervention effects, was low. Referrals were tracked to verify outcomes for all participants who reported having linked to care. This minimized the risk of bias that would have resulted from reliance on self‐reported data or incomplete tracking of referrals.

The study also had some limitations. First, it was an open‐label study: knowledge of the interventions may have influenced participants' decisions to remain in the study. However,Colpomimus

Colpomimus colpodoides is a species of beetle in the family Carabidae, the only species in the genus Colpomimus.

References

Category:Platyninae


One of the textbooks for my “Judaism, Christianity, and Islam” class has this quote on the moral of the Garden story in Genesis 3. It’s long, but it’s good, and I thought it was worth sharing.

=====

Who or what is responsible for man’s expulsion from Eden? In order for man and woman to be responsible for their behavior they would have to be free both to abstain from eating the fruit of the Tree of Knowledge and to understand the consequences of eating from it. Man surely was not without all knowledge before he partook of the Tree of the Knowledge. He knew enough, for instance, to name the beasts which the Lord God paraded before him. He certainly knew that the woman was “bone of my bones, flesh447 F.2d 496
UNITED STATES of Americav.James Richard SMITH, Appellant.
No. 71-1230.
United States Court of Appeals, Third Circuit.
Argued June 10, 1971.
Decided June 16, 1971.

Appeal from United States District Court for the Eastern District of Pennsylvania; John P. Fullam, Judge.

1
James W. Tracey, III, Wollman, Tracey & Schlesinger, Philadelphia, Pa., for appellant.

2
Richard R. Galli, Asst. U. S. Atty., Philadelphia, Pa. (Louis C. Bechtle, U. S. Atty., on the brief), for appellee.

3
Before STALEY and ADAMS, Circuit Judges, and GARTH, District Judge.

OPINION OF THE COURT
PER CURIAM:

4
Appellant was convicted of having refused to perform alternate civilian service at the Williamsport Hospital in lieu of military service. He had been classified 1-O by his local board despite his assertion of entitlement to a ministerial exemption.

5
Appellant asserts that there was no basis in fact for his 1-O


has since donated blood to three other Americans infected with the virus, including missionary doctor Richard Sacra, NBC cameraman Ashoka Mukpo and Dallas nurse Nina Pham. Sacra recovered. Mukpo and Pham are hospitalized.

Transfusing whole blood from one patient to another has drawbacks, but there is great potential for giving immune globulin, or purified antibodies, said Peter Hotez, dean of the National School of Tropical Medicine in Houston. Unlike whole blood, these purified antibodies could be given to anyone, regardless of blood type, Hotez said.

They would not provoke an immune reaction. And they would not risk exposing people to other blood-borne diseases, such as malaria or HIV. Any facility with the ability to do blood banking could handle these procedures. That could allow the therapy to offered across much.
In the correspondence of Mrs. S. R. Riggs, the wife of
another famous missionary to the Sioux, is found a vivid picture
of a Mackinaw boat, belonging to the old Indian trader, Philander
Prescott, in which she ascended the Minnesota in September,
1837. It was about forty feet long by eight feet wide and capable
of carrying about five tons. It was manned by a crew of five
persons, one to steer, and two on each side to furnish the motive
power. Oars were used as far as to the Little rapids, about three
miles above Carver, and thence to Traverse des Sioux poles were
employed. The journey consumed five days.
Illustrative of the size and capacity of some of the canoes
used by the traders, we find George A. McLeod in April, 1853,
bringing down from Lac qui Parle


a small field of wheat, probably the
first ever raised in the valley. It certainly was fitting that this
first year of steamboating in the valley should also be the first
year to grow that commodity which was to play so important a
part in the river's traffic.
The second night was spent at the upper end of Kascta
prairie. It was a charming moonlight night, and a number of
the Yankee's party held a dance on the grassy floor of this level
plateau. The band furnished the music (some of the dancers
said that several mosquito bands were out too) .
Early Wednesday the Yankee started up stream again, soon
passing the sign the Anthony Wayne had fastened to a neighbor-
ing tree the w r eek before. On the mound at the mouth of the
Blue Earth our travelersClarion, 12; Minnesota, 8; Ocean Wave,
6; J. Bisscll, 5; Red Wing, 3; and Fire Canoe, i. The total
trips were 292, an increase of 85 from the year before. The
last boat was the Antelope which arrived at St. Paul on the
1 4th of November.
The winter of 1857-8 proved very mild, and the river broke
up unusually early. The first boat to leave St. Paul for the
Minnesota was the Jeannette Roberts, Captain Thimens, on
March 2Oth, but the Medora, Captain Charles T. Hinde, follow-
ing in a short time, passed her before reaching Shakopee. In
doing so, the boats rubbed too close together, and one of the Me-
dora's wheels was injured, so that she had to tie up an hour or
two for repairs. She managed again to overtake and pass the
Jeannette while the latter


were in total
131, as follows:
From St. Paul From the West
Favorite 44 4
Jeannette Roberts 31 8
Frank Steele 19 "
Freighter 2 I
Ocean Wave 2 2
STEAMBOATING ON THE MINNESOTA RIVER. 147
/
Time and Tide 2 i
Isaac Shelby I i
Belfast i i :
Total 102 29
The total arrivals from the Minnesota at the St. Paul wharf
were 300, which included some boats, like the Antelope, which
did not come to Mankato at all. Navigation continued this year
until quite late, the last boat to pass down over the Little rapids
being the Jeannette Roberts on the 6th of November.
In 1860, the Minnesota again broke up quite early and the
first boat, the Time and Tide, left St. Paul March iQth, reach-
ing St. Peter on March 2ist, and Mankato the next morning.
The river was quite low this spring and noneof the freight was now being carried in barges, w r hich,
having no occasion to stop in St. Paul, passed down the Missis-
sippi without being registered in the St. Paul wharfmaster's
books.
The year 1867 was exceptionally good for boating, as a fine
stage of water continued during the entire season. The first
boat to land at Mankato was the Chippewa Falls on the i8th of
April .
During the summer and until the first of September, the
Mollie Mohler, Captain H. W. Holmes, made daily trips be-
tween Mankato and Belle Plaine, a distance of 175 miles, making
close connections at the latter place with the St. Paul trains.
She would leave Mankato every morning at 8 o'clock and arrive
at Belle Plaine about 4 o'clock in the afternoon, and then leave
STEAMBOATING ON THE MINNESOTA RIVER. 155
Belle Plaine


of
May. She struck a snag as she was coming up the river, under
a full head of steam, well loaded with passengers and freight, and
sank in twelve feet of water. None of the passengers were in-
jured, and nearly all the freight was recovered, but the boat itself
was a wreck. Her machinery and upper deck were eventually
removed, but the hull lies in the sands of the Minnesota to this
day.
In 1868, the Chippewa Falls was again the first boat at St.
Peter and Mankato, arriving at the latter place on the 3ist of
March. Navigation was not nearly as good this year as the
year before, yet by the first of May there had been over 50 steam-
boat arrivals at Mankato. No new boat, as far as known, en-
tered the river this year ;Capt. George Houghton;
Ariel, Capt. James Houghton; City Belle, Capt. A. T. Chamblm; Clara
Hines ; Eolian; Fanny Harris; Favorite, Capt. P. S. Davidson; Frank
Steele; Jeannette Roberts; Victor (barge). Total arrivals, 318.
1862. Albany, Capt. Webber; Antelope, Capt. George Houghton;
Ariel, Capt James Houghton; Clara Hines; Favorite, Capt. Edwin
Bell; G. H. Wilson; Jeannette Roberts, Capt. N. Robert; New Ulm Belle,
Capt. Scott; Pomeroy. Total arrivals, 413.
1863. Albany, Capt. Webber; Antelope, Capt. George Houghton;
Ariel, Capt. James Houghton; Eolian; Favorite; Flora; G. H. Gray;
Jeannette Roberts, Capt. N. Roberts ; Pomeroy ; Stella Whipple. Total
arrivals, 177.
1864. Albany, Capt. Jones; Ariel, Capt. James Houghton; Express;
Firesides, Capt. Joseph Hopkins; Henderson (barge), Capt. Frank
Aymond; Jeannette Roberts; Mollie Mohler, Capt. George Houghton;
Monitor; St. Cloud, Gapt. James Houghton; Stella Whipple, Capt. J. V.
Webber; Turtle. Total arrivals, 166.
1865. Addie Johnson ; Albany,


lung were acetone-fixed and then incubated with 10% normal rabbit serum in PBS (10 minutes, 37°C) to block nonspecific staining. Sections were then incubated with mouse anti-intercellular adhesion molecule-1 (ICAM-1) or rabbit anti-myeloperoxidase (MPO) overnight at 4°C, followed by incubation with biotinylated donkey anti-rabbit or donkey anti-mouse IgG (1:200) for 30 min. Positive staining was revealed by diaminobenzidine, according to the manufacture's instruction of the ABC kit. The number of MPO positive cells was counted within a field of view under the microscope with a 20 × objective lens and 5 fields were selected randomly in each section with the Imaging-Pro Plus 6.0.

Real-time reverse transcription-polymerase chain reaction (RT-PCR) {#Sec8}
------------------------------------------------------------------

Real-time RT-PCR analysis was performed as described previously with some modifications \[[@CR10],[@CR11]\]. Briefly, total RNA was extracted from lung tissue as describedstaining was carried out as described previously. The cells were fixed with 3.7% paraformaldehyde and permeabilized with 0.25% Triton X-100. After rehydrating with 5% bovine serum albumin, the cells were exposed to rabbit anti- NF-κB p65. On washing 3 times with PBS, they were exposed to goat anti-rabbit IgG. The cells were then stained with 3,3′-diaminobenzidine and the negative control group received only the secondary antibody. The cells were analyzed under inverted microscope. Total and nuclear proteins were extracted from cells to measure the NF-κB p65 at the end of observation.

Western blotting {#Sec13}
----------------

The cells were washed twice with cold PBS. Then, cells were lysed with SDS sample buffer containing 50 mM Tris (pH 7.4), 2% SDS (wt/vol), 5% 2-mercaptoethanol and 10% glycerol. Cell homogenates were centrifuged at 10,000


decrease of NF-κB activity, which plays a crucial role in regulating the expression of proinflammatory molecules including TNF-α and MCP-1. The molecular mechanism behind the protective effect of Ginsenoside Rb1 on the LPS-induced lung injury is unclear and requires further identification, although the advantage of using Ginsenoside Rb1 is evident.

**Competing interests**

The authors declare that they have no competing interests.

**Authors' contributions**

QY carried out the lung histologic study, cytokines detection, immunohistochemical study and drafted the manuscript, Y-WJ participated in the molecular biology studies and cell culture. T-TM carried out the ultrastructure assessment. Q-HF participated in the design of the study and performed the statistical analysis. LP conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the finalmanuscript.

The study was supported by Beijing Municipal Health Bureau Youth Research Foundation (QN2010-022), Beijing, China. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript. Study on Railway Workers Chronic Disease Management Network Information Platform No. 2013Z003-C.


Mr. Hawkes talked real estate until he was finished his muffin. "Well, I'm off," he said, with a final gulp. "Don't work too hard, Lucan."

Ivy stumbled in while I was washing my dishes later. Actually, I was washing her dad's dishes too. He'd left them in the sink. Ivy shuffled towards the refrigerator in red sweat shorts and a long yellow T-shirt with a picture of Snoopy on the front. She didn't smell like lemon, not even like shampoo. She must not have showered yet, but I couldn't catch any hint of last night's bug lotion either. Way too much thought was going into what Ivy didn't smell like. I gritted my teeth and shifted my concentration to the dishes.

"Morning," she mumbled groggily.

"Morning," I said back.

We didn't talkquasi provides such fetus the status of an independent patient, to whom both the physician and the mother would have stronger moral obligations. In some countries the landmark of viability is reflected in the legislation on legal abortion for medical reasons. The fetus would in this perspective at a given timepoint (viability) be considered as a patient, irrespective of the mother's preferences (Chervenak et al., 1993). This is tempting, but not true: the fetus -- irrespective of its gestational age- is dependent on the mother and her body, and no treatment can be offered without involving the mother as well. For this reason maternal consent for any fetal therapy is necessary. It is the mother who bears the burden of fetal therapy (including its failure). She acts as the


indicate that about $11.6 billion were paid in 2013, with the lowest taxes in Montana ($2.2 million) where 4,000 undocumented immigrants reside to more than $3.1 billion in California, which is home to more than 3 million undocumented immigrants.

Like all Americans, they also pay sales and excise taxes when they pay for goods or buy services -such as gasoline, utilities, and clothing. Further these undocumented immigrants also pay property taxes. Current evidence indicates that at least 50 percent of these undocumented immigrant homeowners also file income tax returns using Individual Tax Identification Numbers (ITINs). However, there are countless more of them who never file income tax returns but still have their employers deduct taxes from their paychecks.

President Obama’s executive actions are not enough

Thousands of undocumented immigrants are waitingQ:

Mercurial is ignoring new files

How can I make new files show up in hg status output?
Newly created files in my project directory do not appear when I run hg status.  If I run hg status --all, I see that they are ignored.  I would expect that newly created files would be indicated as untracked and that I would have to manually ignore them, rather than the other way around.
The new file type is not listed in .hgignore nor do I have anything that should affect it in my mercurial.ini.

# .hgignore

syntax: glob

## Specific Files ##

## File Types ##
*~
*.pyc
*\#

## Directories ##
venv/*
.idea/*
.pytest_*
__pycache__/*
*/__pycache__/*

; mercurial.ini

[ui]
username = Lorem Ipsum <loremipsum@dolorsitamet.com>
editor = "C:\Program Files\emacs-26.1-x86_64\bin\emacsclientw.exe"

[pager]
pager = C:\Program Files (x86)\less-530-win32-static-x86\less.exe

[color]
mode = win32

[alias]
; Prevents creation of .orig files
undo = revert --no-backup

A:

The trouble is that hash is


short-bond RVB was found recently [@Cano]. Although the $S=1/2$ and $S=1$ states we study here may not be its exact lowest states in these sectors, one can still expect them to be good variational states—the actual excitations of the Cano-Fendley Hamiltonian should be very similar.

We characterize the RVB spinons in Fig. \[fig2\]. The $S=1/2$ distribution $P_{AA}(r)$ demonstrates a well-defined intrinsic spinon wave packet, decaying as $e^{-r/\lambda}$ with the spinon size $\lambda = 2.96(1)$. The $S=1$ distribution $P_{AB}(r)$ is peaked at short distances and appears to decay as $r^{-\alpha}$ with $\alpha \approx 0.6$. This implies marginal deconfinement due to weak attractive spinon-spinon interactions. In Fig. \[fig2\] we also show that the length-scales observed in $P_{AA}(r)$ and $P_{AB}(r)$ are manifested in the $S=0,1$ correlation function $C(r)$ as well. Hence, the distributions dothe effective spinon-spinon interactions is not immediately clear). Note that we have only studied the lowest $S=1$ state, and in higher states the kinetic energy should overcome the weak attraction, leading to essentially independent spinons, as found when comparing the critical $J$-$Q$ model with a gas of free bosonic $S=1/2$ excitations [@Sandvik3].

In the simple RVB spin liquid, we also found weak attractive interactions, but in this case the spinons are small. The differences between the RVB liquid and the critical $J$-$Q_3$ model should be due to the fact that the spin correlations decay exponentially in the former (and there is a spin gap), while they have a power-law decay the latter. Both models exhibit algebraic dimer correlations, which should be responsible for the residual spinon interactions. In the


against Cohmad, founder Maurice “Sonny” Cohn, daughter Marcia Cohn, Robert Jaffe, Richard Spring, Alvin J. Delaire, Jr., Stanley Mervin Berman, Jonathan Greenberg, Cyril Jalon, Morton Kurzrok, and Rosalie Buccellato, among more than two dozen individuals and trusts in U.S. Bankruptcy Court in New York. The lawsuit claims that up to 90 percent of Cohmad’s income came from referring clients and that the firm had a “symbiotic” relationship with Madoff, having earned hundreds of millions of dollars from the fraud.  The lawsuit seeks more than $100 million paid to Cohmad six years prior to Madoff’s firm declaring bankruptcy, and more than $105 million in profits Cohmad employees and their families withdrew from the investment accounts they held with Madoff.

On June 22, 2009,  the U.S. Securities and Exchangea stop on the St. Louis, Memphis & South Eastern Railroad, which began construction on 22 September 1902, with the intention of linking Perry County with St. Louis in time for the 1904 World's Fair.  A post office was opened in 1904 (closed in 1996).

Floods
The Town of Menfro is located on Cinque Hommes Creek, which is usually called "Menfro Creek" by the local population. Menfro Creek empties into the Mississippi River just a mile (1.6k) downstream from the Town of Menfro. When the water level in the Mississippi River rises, the Menfro Creek runs backwards, taking in the rising water from the Mississippi. As such, when the Mississippi River floods, so does Menfro.

Three major floods have affected Menfro (1943, 1973 and 1993).  Each time, the Town


been stopped earlier that morning in the Chevrolet van. Among the items discovered in the Concord house were firearms, ammunition, empty shells which had been fired from the .380 Walther and the .38 caliber Rossi, pipe bombs and Molotov cocktails, several SLA "communiques" (including the original of Communique No. 1 from which the copies received by the news media had been duplicated), a typewritten list containing the names and addresses of the five news organizations to which Communique No. 1 had been sent, a hand-drawn map of the Foster ambush-murder scene, Oakland School District publications from which Foster's photograph had been torn out, a document containing the time and date of the school board meeting following which Foster had been killed, cyanide bullets similar to those which killedminority jurors to reevaluate their positions in light of the views of the majority and an assertion that the case at some time must be decided.[1]
*820 Deliberations then resumed extending throughout the day. At 6:30 p.m. on June 9, the jury returned to the courtroom. After some discussion, the court reread two instructions, CALJIC Nos. 1.00 and 17.40.[2] The foreman indicated that the instructions were sufficient and asked to resume deliberations. At 6:37 p.m., the jurors retired. They returned to the court at 7:04 p.m. at which time verdicts of guilty were rendered against each defendant for first degree murder and attempted murder. The verdicts against Remiro were dated June 8, 1975; those against Little were dated June 9, 1975. Each verdict was read in its entirety and


C. (1978) 21 Cal.3d 888, 894 [148 Cal. Rptr. 366, 582 P.2d 957].) Officer Duge stopped the van because he suspected the possible involvement of the occupants in criminal activity. His suspicions were objectively supported by the unusually slow speed of the vehicle (Williams v. Superior Court (1969) 274 Cal. App.2d 709, 712 [79 Cal. Rptr. 489]), the lateness of the hour (People v. Rosenfeld (1971) 16 Cal. App.3d 619, 622 [94 Cal. Rptr. 380]), the frequency of burglaries and thefts from vehicles in the area (Rosenfeld, supra, at p. 622), and the circuitous route of the van through the neighborhood, suggesting to Duge the occupants were "casing" the area preparatory to some criminal activity (People v. Jackson (1968) 268 Cal. App.2d 306, 310 [74 Cal. Rptr. 40]).been shown Horner's written consent before he conducted the warrant search.
(11) Abandoned property is subject to search and seizure without a warrant. (Abel v. United States (1960) 362 U.S. 217, 241 [4 L.Ed.2d 668, *834 687, 80 S.Ct. 683]; People v. Smith (1966) 63 Cal.2d 779, 801 [48 Cal. Rptr. 382, 409 P.2d 222].) A landlord may consent to a search of premises abandoned by a tenant (People v. Urfer (1969) 274 Cal. App.2d 307, 310 [79 Cal. Rptr. 60].) Here the owner of the premises, not himself a law enforcement official, determined that his tenants had abandoned the property. This determination was based on the belief that his tenants had themselves unlawfully fired the house and permanently absconded. This conclusion in turn was based on information from