ME into body tissues and milk (most of the HPx derived from OXCHO: 59.2%). The other two diets were lipogenic, and lipogenic nutrients originate either from fibre or dietary fat, or from body reserves \[[@pone.0151215.ref049]\]. Fat mobilization was found in OP and SH, although greater OXF (76.6%) was found in SH than OP (49.2%). Therefore, BRL behaved as a glucogenic diet, SH as a lipogenic diet and OP as intermediate, but due to possible asynchrony between protein degradation and type of carbohydrate, the NH~3~-N increased in OP and SH and fat mobilization increased to meet energy demand and milk performance.

Conclusions {#sec018}
===========

This paper provides data on energy partitioning, substrate oxidation, carbon and nitrogen balances, methane emissions and milk performance in Murciano-Granadina goats during midlactation fed mixed diets. Replacing 59%dropped his loincloth and uncovered the region where his
genitals ought to be. Cheetara gazed - the youth was not yet aroused so
the flesh was nestled within tufts of white and black fur. Invisible.
Except to a woman's judging eyes....

Overwhelmed by urges fomenting between her legs, she grasped his hips
and shoved his crotch into her face. Against her cheek she felt his
warm, firm tip. His length started to unfurl and sputter. She drew
away, still squeezing and holding onto his cheeks, and watched as his
rough, pink organ poked through the fuzz.

Unfurl and sputter? Dude, you need to see a regular doctor, ASAP.

Cheetara blew into a balloon while Bengali stroked her mane. When full
of air she only pinched its tip. Then she rubbed it along the fur
between the tiger's thighs. She felt,


its tip. It stood horizontal - and she lathered the
glans with the rubber until the whole of the head what enveloped by the
toy. It popped and the youth replied with a shudder. The woman replied
with a chuckle. She kissed where the flesh was reddened by the burst
and the tiger repeated that head to toe jerk.

Um, what? What the fuck is going on here? First of all, bitch, you pop a balloon near my junk you gonna get the pimphand. Second of all, "lathered the glans" until "the whole head was enveloped"? Is Bengali's dick in the balloon? Is the balloon Bengali's dick? What the fuck does this mean? And how did the Thundercat penis make the balloon pop? AND WHY AM I ASKING THESE QUESTION OH GOD LOOKKea. The project won a series of approvals from Hawaii, including a permit to build on conservation land in 2011.

Protests disrupted a groundbreaking and Hawaiian blessing ceremony at the site in 2014. Construction stopped in April 2015 after 31 protesters were arrested for blocking the work. A second attempt to restart construction a few months later ended with more arrests and crews retreating when they encountered large boulders in the road.

Hawaii Attorney General Clare Connors said the state Supreme Court ruling must be respected, but that people’s right to free speech is also protected and that the conversation should continue.

“It is important that it not stop even as the telescope is constructed,” Connors said. “For safety we encourage that this conversation happens somewhere other than on Mauna Kea.”

The


Observatory Board of Governors. “It has been a long process to get to this point.”

Richard Ha, a Native Hawaiian farmer who lives on the Big Island and supports the project, said he thinks the telescope will provide an opportunity for the community to learn and grow.

He does not practice religion on the summit, he said, but he does visit Mauna Kea and respects the connection Native Hawaiians have to the place.

“Once you get above the clouds, you’re in a different world,” Ha said. “You’re in the universe and it’s just amazing to look up and see so many stars. It makes you feel like humans are just a small part.”Ex-NYPD officer indicted on murder charge in New Orleans A former New York City police officer has been indicted on murder charges in Louisiana

NEW ORLEANS -- A former New York City police officer has been indicted on murder charges in Louisiana.

The New Orleans Advocate reports 29-year-old Gerardo Bugallo-Beret was charged Thursday with second-degree murder in the March shooting death of Tyrone Reese.

A press release from District Attorney Leon Cannizzaro's office says Bugallo-Beret shot 29-year-old Reese in front of an apartment building in the Treme neighborhood. Bugallo-Beret says he shot Reese in self-defense after Reese verbally threatened him. Cannizzaro's office says Reese was unarmed.

Bugallo-Beret served as an NYPD officer from July 2014 to May 2016. He left the force after being charged with misdemeanor assault following a reported fight


circumstances. Even a direct perpetrator need not have known that his or her act amounted to an inhumane act either in the legal or moral sense. Furthermore, all acts of assistance, by words or acts and omissions, that lend encouragement or support will suffice if the accused knows or is aware that such conduct can or will facilitate the use of what happens to be an illegal tactic or form of treatment.

The Convention Against Torture and the 1949 Geneva Conventions both require the United States to either initiate prosecution of or to extradite every person who is reasonably accused of having criminal responsibility with respect to torture. President Obama should confirm to the nation that no one is above the law.

Jordan J. Paust is the Mike & Teresasituation, the media is in control. They can change interview times. They can decide not to use your quotes or your product in a feature. Their job is to put out the best possible stories and they are not concerned whether your business gets exposure. Do not be difficult. Cater to their needs. Understand if you don’t fit into a particular story. If you want to control a story or insure your product is featured, then you must use paid advertising.

You have no control over what they say.

You may be featured along with three or four of your competitors in the story. They may do a review that turns out unfavorable. We cannot proof read an article for those print. You can’t force them to include your biography


a reduced price half-day package for new clients. A management consultant or executive coach could propose a staff seminar instead of consulting/coaching work. Once clients see you in action, they’ll be more willing to spend.

6. Find the silver linings. When companies cut back on staff, opportunities are created. With fewer people on the payroll to handle essential tasks, downsized organizations present possibilities for project work, interim assignments, and outsourced functions. Economic changes beget other needs. People who are out of work need resume writers and career coaches. Folks concerned about their finances need investment advisors and financial planners.

Landing clients during a down period requires not just more marketing, but more strategic marketing. So instead of getting depressed by the news, get inspired by it. When you hear aboutsaid good-bye, come back now and called them by name. I loved that man so much and never , ever told him enough. “Do you hear me now dad?”

Unlike the readers of my last post, who were so articulate and insightful about the sweetness of solitude, many professional researchers have had a much harder time recognizing that solitude can actually be beneficial. Maybe part of the reason is that psychologists – especially social psychologists – are so attuned to humans as social animals who need and crave connection with other people. In fact, the title of a journal article that has attracted much attention over the years is “The need to belong.”

I don’t dispute the social needs of humans. I just don’t see them as incompatible with an


of us.) Of course, even living alone does not preclude the possibility of having other people around – even lots of them – but it can add up to lots of time spent with no other hovering humans.

Solitude

Those who would pity us for the time we spend alone think of our experiences as loneliness. That’s the negative sense of being by yourself – having no other humans present with whom you can connect in a meaningful way, but wishing that you did. Surely, there are singles who feel lonely when they are in their homes (or even out and about) on their own, just as there are coupled people who feel lonely when their romantic partner is not at their side. But there is far more to theprofessor at UC Santa Barbara. belladepaulo.com

Whenever you are lucky enough to work with the media, remember the Boy Scout Motto, “Be Prepared.” Do your homework in advance, research your topic, ( of course if it’s yours you should know it inside and out.) One trick I learned is to prepare a set of questions and quiz myself on them and practice until my answers are short, crisp, pithy [love that word] – the kind that make great soundbites.

1. Tell them what kind of information you will be able to provide so they know you will give them good content. NEVER, NEVER sell on radio or TV. You will quickly get on their “never call” list again. If you provide good content and are good on camera, you will


to practice your talk; if you don’t know if by now, it’s too late, But being as calm and as clear headed from deep breathing can work wonders.

Watch for next time’s tips where we polish off this list – and good luck!from the National Diabetes Information Clearinghouse. Examine the list of symptoms of hypoglycemia: hunger, shakiness, perspiration, dizziness, possible loss of consciousness. See also this webpage from the Hypoglycemia Support Foundation, about changes in personality (outbursts of temper, mood swings, etc.). That's Mrs. Johanssen, isn't it?

If Mrs. Johanssen is giving herself too much insulin, she could be hypoglycemic. She might be doing this by accident, misreading the instructions, or she might be doing it on purpose because she fears the effects of diabetes or wants to eat more sweets, or the doctor might have prescribed too high a dosage. Since she is aware of the condition, however, it is far more likely that her body is creating a little insulin on its own but unreliably, so her insulin levels


Johanssen gets into a fight with Mr. DeMartino at a PayDay warehouse store (think Sam’s Club or Costco) over a “Cheez Log.” She also asks for help from Daria and Jane (once again not recognizing them) in reaching chocolate on a high shelf, saying she had a seizure some time ago. The seizure might have been the fainting spell she had in “Café Disaffecto” or something more serious.

It is in “Psycho Therapy” that we learn a little bit about why she is the way she is, when she is in therapy with Dr. Jean-Michel Millepieds and says, “Maybe I do use food for comfort, but at least a chocolate bar never told me I was an accident.” Ouch. Interestingly, Mrs. Johanssen does not seem to recognize Quinn, thoughawaiting her appeal in Kinsington Prison. (It's amusing that the first pen pal encountered in the book is from Australia and the last is from Zimbabwe, the literal A-to-Z of world nations.)

Rhonda has appeared in several fanfics in different forms, but to my knowledge none of Daria's other e-mail pals has ever shown so much as the end of his/her nose in any story. (If I am wrong, please set me straight.) That's sort of weird, since here you have several thumbnail character descriptions all ready to go, with names, ripe for development in nearly any direction the author wishes to take, and they're just sitting there. Such a shame. So much story, nothing happening. [sigh] You get the message.

Speaking of Australia, Deref has sent in some interesting


of "Murder, She Snored" on cable TV at a relative's home, but everyone was there with me and I didn't want to look interested in a cartoon, even if I was becoming quite interested in it. That was all I knew about Daria until I saw a website about it in late 2001 (still not sure which one it was) and read part of that crossover Daria/Predator story. I finally found the rest of the fandom in April 2002, after the show was COMPLETELY FREAKIN' OVER WITH GAH DAMN IT but I am not bitter over missing everything, thank God, or I'D BE PRETTY GAH DAMN MAD ABOUT IT.

Why was I attracted to the show? A lot of people say their love of Daria is based on herthe Fashion Club go “Eww!” in unison.

And yet . . . he’s something more. He doesn’t blackmail Brittany for sex favors in “The Lab Brat,” instead being content to have her be his personal gopher (go for this, go for that, etc.) while he works on the mouse maze. He has the capitalist spirit in spades, being the creator/manager of an Internet website selling exotic candies (“Prize Fighter”). There are little hints dropped along the way (his wide vocabulary, for instance) that he is brighter than most students, and he is certainly clever. His Ultrasuave Universe website in The Daria Diaries speaks of interests in collectible items, Three Stooges movies, Jerry Lewis, Playboy, The X-Files, history, movies, Star Wars, brassieres, comic books, music, and Monty Python trivia. (He


and better things. That would be rrrowrrr, feisty!

Yo, my homies, this be X talkin' at ya! Be excellent to each other all year long, and don't hog the nog!

Peace out on Earth, and Good Will Hunting!

This has been another Very Special Message from X, the Holiday Formerly Known as Christmas, speaking from the Holiday Island High School Christmas Party at the Holiday Island High School Gym. This greeting is not void even if prohibited by law. Don't Hog the Nog is a trademark of X. All Rights Reserved.

One of the background characters described on Wraith's Sick, Sad World website is a guy called the Blind Man. He is said to have appeared in "Esteemsters" but later reappeared fully sighted. I've watched the SSW appearance of the guy whodue to either condensation or a build-up of surface contamination. The structure is also designed to prevent electrical arcing between the interrupter and the frame, and to prevent corona discharge caused by the ionization of air due to a high electric field gradient near a surface.
In one general aspect, a switchgear assembly includes a vacuum interrupter assembly having an internal switching contact. A conductive current exchange is in electrical contact with the switching contact, and the current exchange defines an internal chamber within the current exchange. A plug of non-conductive, compliant material has a first portion that extends into the internal chamber and is positioned against the current exchange. An insulative encapsulation surrounds the vacuum interrupter assembly, the current exchange, and the plug.
Implementations may include one or more


Q:

How can I specify a specific TFS folder in Visual Studio 2008

I'm trying to add a Team Foundation Server address to Visual Studio 2008.  However, the modal won't let me specify a directory to use after the port-number.
In other words, I'd like to specify http://www.example.com:8080/tfs .  However, using the following modal (pictured below), I'm only able to specify http://www.example.com/tfs:8080 (which isn't valid).
If it matters, I'm running VS2008 in Windows 7, attempting to connect to TFS 2010.

A:

It's been a long time since I used VS2008, but you should be able to either type the full URL in, including the protocol, or leave off everything but the server name.
So, http://examplecom:8080/tfs or example.com
Also, make sure you've installed the VS 2008 forward compatibility hotfox: https://blogs.technet.microsoft.com/chrad/2010/01/08/visual-studio-2008-connecting-to-tfs-2010-server/

the 6-4, 220 lb. LB attended training camp with the Bombers, before the team released him in mid-June. Before that, he’d enjoyed a stand-out five-year career at Maryland, where he moved around the defence and a strong junior season. That year, he put up 100 tackles, 3.5 sacks and three picks. In 2011, he started off with 35 tackles and two picks in four games, before being sidelined with injury, and returned the next year.

The other new LB, Wilson, is a 6-2, 205 lb. athlete who played four years at Western Michigan University, starting 45 of his 49 total games. He put up 245 tackles and nine picks over that span.

Downs started 10 games as a senior at Delta State in 2012, snagging 44 passes for 550 yards


in the Mirror..." "There's no turning back now that I've realized the seriousness of the crime." "You've broken my heart." "Line Out!" "Kasuga!" "Darling!" "A..." "Ayukawa!" "Kasuga..." "You've stopped time once too often!" "We can never be at the same place together ever again!" "A..." "Ayukawa!" "Immobilized Madoka!" "Kyosuke's Mysterious Watch." "It was... a totally unexpected situation..." "We'll aim for Wimbledon!" "One, two!" "One, two!" "Looks like you're really into it, huh, Hikaru..." "You bet!" "I mean, it's been a while since the three of us went out together." "Madoka, you won't beat me!" "Oh, yeah?" "!" "I'll remember those words!" "This is going to be so much fun, huh, Darling!" "Huh...?" "Uh-huh..." ""I hope tomorrow comes quickly!"" "Uh-oh!" "Hikaru!" "Hikaru!" "Hikaru..." "Huh?" "!" "Thank goodness!" "It's all"Because, if you use it too often..." "Quiet, Ojiisan!" "Oh?" "The red fog people will get suspicious..." "Wh..." "What?" "!" ""There!"" ""Oh, no!"" ""Kasuga!" "That was amazing!"" ""You're awesome, Kasuga!"" ""Gee, you're too kind!"" "Ow!" "Darling!" "How could you be dozing off when it's only noon?" "!" "That hurt..." "Oh?" "Am I up already?" "!" "Get some points back, okay...?" "Ready or not!" "This way, she won't get hurt." "Ayukawa..." "Oh!" "Better not!" "Why am I always like this?" "!" "Morals!" "Morals!" "Morals!" "Ayukawa..." "No matter what..." "Ayukawa surely is gorgeous..." "What're you up to, all of a sudden?" "!" "You perverted old fart!" "M..." "Miss, please don't shout at an old man..." "I was only trying to... find something that I've, er, lost..." "Old or not, a


to come play tennis leaving the elderly behind?" "!" "To top it off, look at these bozos you brought along!" "Okay!" "Is everybody paired up and ready to go?" "Yep, sure are!" "So, we'll be having a round-robin match." "And, the winning pair, as partners, will exchange the "Kiss of Victory!"" "What?" "!" "A kiss?" "!" "Yes!" "Yes!" "I consent to that!" "D..." "Do you have any idea what you're saying, Komatsu?" "!" "What's wrong with that?" "Isn't a certain person here into things of that nature?" "Kyosuke, lose!" "Kyosuke, lose!" "Ayukawa is..." "Kyosuke, lose!" "Kyosuke, lose!" "...still upset about what happened..." "Kyosuke, lose!" "Still... the thought of Ayukawa and Yuusaku kissing..." "Kyosuke, lose!" "...is something I can't possibly approve of!" "Kyosuke, lose!" "Kyosuke, lose!" "Whatdidjasay?" "!" "Why,tough, and now we're only a point away from victory..." "Advantage:" "Kyosuke-Hikaru Team!" "If I win this point, Ayukawa won't be kissing!" "But, wait a second..." "If we win, then I'll be kissing Hikaru..." "I..." "I won't make it!" "It..." "It won't stop!" "Line Out!" "My body..." "Kasuga!" "Darling!" ""A..." "Ayukawa!" "Ayukawa, where are we?" "!"" ""Kasuga..." "You've stopped time once too often!" ""We can never be at the same place together ever again!" ""Looks like we're through."" ""A..." "Ayukawa!" ""Why..." "Why can't I stop time?" "!" "I was only doing it for you!"" ""Wait!"" ""Darling..." "We can't always be together like we are now!"" ""You're kidding!" "Why are you saying that?" ""Why can't we be like the way we are?" "!" ""Why can't I stop time?" "!""


P\<0.01, \*\*\* P\<0.001, ns = not significant. (C) Cell lysates were analyzed via western blot using anti-HN, anti-phosphorylated eIF2α, anti-eIF2α, and anti-GAPDH antibodies.](ppat.1006948.g001){#ppat.1006948.g001}

Since the phosphorylation of eIF2α is critical for SG formation, we evaluated the phosphorylation status of eIF2α in HPIV3-infected cells and found that the level of phosphorylated eIF2α increased at 12 hpi, peaked at 24 hpi, and remained stable until 36 hpi. ([Fig 1C](#ppat.1006948.g001){ref-type="fig"}). Furthermore, we examined the distribution of phosphorylated eIF2α via immunofluorescence and found that little phosphorylated eIF2α was detected in mock-treated cells. In contrast, both HPIV3 infection and AS stimulation obviously increased the level of phosphorylated eIF2α, and phosphorylated eIF2α was recruited into SGs, which co-localized with G3BP ([S1C Fig](#ppat.1006948.s001){ref-type="supplementary-material"}), suggesting that HPIV3 infection activates eIF2α phosphorylation and subsequently induces SG formation.

Assembly ofwith or without CHX in the presence of AS for another 1 h. (A) Cells were immunostained for TIA-1 (green) and G3BP (red). Nuclei were stained with DAPI (blue). The white scale bar corresponds to 10 μm. (B) The percentage of cells containing SGs was quantified in three independent experiments. (C-H) HeLa cells were mock-infected or infected with HPIV3 (MOI = 1) for 24 h and subsequently mock-treated or treated with CHX for another 1 h, 2 h, or 3 h. (C) Cells were immnostained for HPIV3 (purple), TIA-1 (green), and G3BP (red). Nuclei were stained with DAPI (blue). The white scale bar corresponds to 10 μm. (D) The percentage of cells containing SGs was quantified in three independent experiments. (E) Cell lysates were analyzed via western blot


contrast, PKR-knockdown cells failed to form SGs upon HPIV3 infection ([Fig 4A](#ppat.1006948.g004){ref-type="fig"}, panel "sh-PKR," and 4B). Similarly, neither RNAs from HPIV3-infected cells nor pIC induced SG formation in PKR-knockdown cells ([Fig 4C and 4D](#ppat.1006948.g004){ref-type="fig"}; [S3A and S3B Fig](#ppat.1006948.s003){ref-type="supplementary-material"}), suggesting that HPIV3 induced SG formation in a PKR-dependent manner. Because SGs were still able to form upon AS treatment in PKR-knockdown cells ([S3C and S3D Fig](#ppat.1006948.s003){ref-type="supplementary-material"}), the inhibition of SG formation in PKR-knockdown cells during HPIV3 infection or pIC treatment was not due to an intrinsic defect of cells in response to stress.

![HPIV3 triggers SG formation in a PKR-dependent manner.\
(A and B) HeLa cells with or without PKR knockdown were infected with HPIV3 (MOI = 1) for 24 h. (A) Cells were immunostained for HPIV3 (green) and G3BP (red).supernatants were collected for a plaque assay to determine the viral titer. Data are represented as means ±SD. Student's t test: \* P\<0.05, \*\* P\<0.01, \*\*\* P\<0.001, ns = not significant.](ppat.1006948.g004){#ppat.1006948.g004}

Next, we detected the phosphorylation level of PKR and eIF2α in both mock- and PKR-knockdown cells during HPIV3 infection. In mock-knockdown cells, HPIV3 infection obviously induced PKR/eIF2α phosphorylation, whereas in PKR-knockdown cells, phosphorylated PKR/eIF2α was not detected ([Fig 4E](#ppat.1006948.g004){ref-type="fig"}), suggesting that HPIV3-induced eIF2α phosphorylation depends on PKR phosphorylation. Interestingly, knockdown of PKR expression significantly increased viral HN protein expression and viral titers ([Fig 4E and 4F](#ppat.1006948.g004){ref-type="fig"}), indicating that HPIV3-induced SGs may play an inhibitory role in viral replication.

Inhibition of SG formation facilitates HPIV3 replication {#sec006}
--------------------------------------------------------

Several viruses have been reported to trigger the formation of SGs that capture viral


or P, and over-expressed N or P distributed homogeneously in \>90% of HPIV3-infected cells ([Fig 7A--7C](#ppat.1006948.g007){ref-type="fig"}), but, to our surprise, we did find that \~8% of cells over-expressing N or \~3% of cells over-expressing P formed IBs in HPIV3-infected cells (due to over-expressed N interaction with P derived from HPIV3 infection or over-expressed P interaction with N derived from HPIV3 infection), and all the cells containing IBs appear to have no SGs ([Fig 7A--7C](#ppat.1006948.g007){ref-type="fig"}; "+"implies a cell forming IBs), indicating that over-expression of N or P does not inhibit HPIV3-induced SG formation unless N or P form IBs, which also implies that IBs may play an inhibitory function on SG formation.

![HPIV3 IBs inhibit HPIV3-induced SG formation.\
(A-C) HeLa cells were transfected with an empty plasmid or plasmid encoding NABclonal), rabbit anti-eIF4A (1:500, ABclonal), rabbit anti-eIF4E (1:500, ABclonal), rabbit anti-eIF4G (1:200, CST), rabbit anti-phosphorylated eIF2α (1:200, CST), mouse anti-G3BP (1:500, BD Bioscience), mouse anti-HA tag (1:2000, Sigma), mouse anti-Flag tag (1:1000, Sigma), and mouse anti-Myc tag (1:200, Santa Cruz). The secondary antibodies used were as follows: Alexa Fluor 647 donkey anti-goat IgG (1:1000, Invitrogen), Alexa Fluor 488 donkey anti-rabbit IgG (1:1000, Invitrogen), and Alexa Fluor 594 donkey anti-mouse IgG (1:1000, Invitrogen).

RNA-FISH {#sec016}
--------

The RNA-FISH assay was performed according to the manufacturer's instructions for the QuantiGene ViewRNA ISH Cell Assay kit (Affymetrix). Cells were fixed in 4% paraformaldehyde solution at room temperature for 30 min and permeabilized with detergent solution at room temperature for 5 min. Protease solution was added to the cells at a suitable dilution (1:1000--1:4000) in


5'-AGAAGAACAGTCAAAGCGAAAG-3';

HPIV3 M protein reverse: 5'-CTCCAACTAATCCCAAAG-3';

Human GAPDH forward: 5'-GAGTCAACGGATTTGGTCGT-3';

Human GAPDH reverse: 5'-GACAAGCTTCCCGTTCTCAG-3';

Mouse IFNB1 forward: 5'-AGTTACACTGCCTTTGCC-3';

Mouse IFNB1 reverse: 5'-TGAGGACATCTCCCACGT-3';

Mouse GAPDH forward: 5'-GCATTGTGGAAGGGCTCA-3';

Mouse GAPDH reverse: 5'-AGGCGGCACGTCAGATC-3'.

HPIV3 mini-genome replicon system assay {#sec022}
---------------------------------------

HeLa cells were infected with vTF7-3 for 1h, then transfected with pGADT7-P (125ng), pGEM4-L (100ng), HPIV3 minigenome plasmid carrying the luciferase reporter gene (50ng) together with pCDNA3.0-N-Myc (100ng) or pCDNA3.0-NΔN10-Myc (100ng, 200ng or 400ng) for 24h. Cell lysates were collected to determine the luciferase activity or analyzed via western blot.

Supporting information {#sec023}
======================

###### HPIV3-triggered SG formation is a general process.

\(A\) HeLa cells were infected with HPIV3 (MOI = 1) for 24 h. Cells were immunostained for HPIV3 (purple), eIF4A/4E/4G (green), and G3BP (red). Nuclei were stained with DAPI (blue). The white scale bar corresponds to 10μm. (B) HEp-2 cells were infected withvolume blood flow quantification. We expected that antenatal distress would be more strongly correlated with volume blood flow than with the arterial resistance indices.

Materials and Methods {#s2}
=====================

Ethics Statement {#s2a}
----------------

The study was approved by the Regional Committee for Medical Research Ethics, Southern Norway, Oslo, Norway (S-05281). Written informed consent was obtained from all participants, and the study was conducted according to the Declaration of Helsinki.

Methods {#s2b}
-------

The present study is part of a larger prospective study investigating psychological distress in three groups of pregnant women, with either a current diagnosis of fetal malformation, malformation in previous offspring, or no history of malformation. The present study describes only the group with no previous or current fetal malformations. Design, choice of psychometric tools, and sample size of the different groups was determined


IES intrusion scores and fetoplacental volume blood flow (Q~UVAC~)), but not with any other distress measure. Intrusion dichotomized at the mean (i.e. 6.8) showed a significantly lower Q~UVAC~ in the more distressed group (mean difference = --0.791 ml/cm/min; 95% CI --1.319, --0.264; *P = *0.004).

In univariate regression analyses, the only distress score meeting inclusion criteria was intrusion. Covariates with *P*\<0.20 were maternal age and fetal gender (see [Table 4](#pone-0057071-t004){ref-type="table"}). In multiple regression models, keeping only covariates with an adjusted *P*\<0.10 (i.e. maternal age), intrusion as a continuous variable was statistically significant (*P = *0.032) and uniquely explained 4% of Q~UVAC~ variance. For intrusion dichotomized at the mean, the *P*-value was 0.003 and explained 9% variance (see [Table 5](#pone-0057071-t005){ref-type="table"}). The effect estimate for the dichotomous variable corresponded to 0.61 SD. The regression models explained 5%between distress measure IES intrusion and umbilical vein volume blood flow normalized for fetal abdominal size (Q~UVAC~; ml/min/cm). IES intrusion scores are continuous in section A, and dichotomized at the mean in section B.

Maternal age does not fulfill criteria of P\<0.10 for continued inclusion into this regression model, but is retained for easier comparison with section A.

B, regression coefficient; β, standardized regression coefficient; IES, Impact of Event Scale; UA, umbilical artery; PI, pulsatility index.

UA PI was significantly correlated with Q~UVAC~ (*r* = --0.30, *P* = 0.003). To explore a possible mediating effect of placental vascular resistance, we included both UA PI and intrusion as predictors in multiple regression models with Q~UVAC~ as dependent variable. Other covariates were tested and included as previously described. The strength of the association between intrusion scores and


medium ([Fig. 6](#pone-0110291-g006){ref-type="fig"}).

![Effect of (A) series 1, (B) series 2, (C) series 3, (D) series 4, (E) series 5 and (F) series 6 chelators, relative to the controls DFO and Dp44mT, on ^59^Fe mobilization from prelabeled SK-N-MC cells.\
Cells were incubated for 3 h/37°C with ^59^Fe-transferrin (0.75 µM), washed 4 times with ice-cold PBS and then reincubated for 3 h/37°C in the presence or absence of the chelators (25 µM). Release of ^59^Fe was then assessed using a γ-scintillation counter. Results are mean ±SD (3 experiments).](pone.0110291.g006){#pone-0110291-g006}

Compounds of series **1**, **3**, **4** and **6** generally displayed high efficacy at mobilizing cellular ^59^Fe ([Fig. 6](#pone-0110291-g006){ref-type="fig"}). In particular, the ligands, **1c**, **1e**, **3b--3f**, **4a**, **4c**, and **6b--6f** all demonstrated comparable ^59^Fe mobilization efficacy to that of Dp44mT, resulting in the efflux ofwas calculated. Results are mean ±SD (3 experiments).](pone.0110291.g010){#pone-0110291-g010}

As previously observed, the redox-inactive iron complex of DFO resulted in very limited ascorbate oxidation ([Fig. 10](#pone-0110291-g010){ref-type="fig"}) [@pone.0110291-Richardson4], [@pone.0110291-Mladenka1], with the ligand acting in a protective manner, significantly (*p*\<0.05) inhibiting ascorbate oxidation at IBEs of 1 and 3 to 47% and 23% of the control, respectively ([Fig. 10](#pone-0110291-g010){ref-type="fig"}). In contrast, the iron complex of the positive control, EDTA, significantly (*p*\<0.001) increased ascorbate oxidation at IBEs of 0.1, 1 and 3 to 208%, 449% and 936%, respectively, in comparison to the control ([Fig. 10](#pone-0110291-g010){ref-type="fig"}). This is in agreement with our previous studies that showed its ability to mediate ascorbate oxidation [@pone.0110291-Kalinowski2], [@pone.0110291-Richardson4], [@pone.0110291-Kalinowski3], [@pone.0110291-Kalinowski4]. Additionally, the Dp44mT-iron complex also mediated ascorbate oxidation, significantly (*p*\<0.01--0.001) increasing it to 129%, 203% and 196% at


anti-proliferative effects ([Table 1](#pone-0110291-t001){ref-type="table"}), iron chelation efficacy ([Figs. 6](#pone-0110291-g006){ref-type="fig"}&[8](#pone-0110291-g008){ref-type="fig"}) and ascorbate oxidation ([Fig. 10](#pone-0110291-g010){ref-type="fig"}), this suggests that the series **3** analogs may act as bidentate ligands that utilize the 8-hydroxyl oxygen and quinoline nitrogen as donor atoms. Significantly, the use of the "hard" oxygen donor atom in series **3** may result in the formation of redox-inactive iron complexes that cannot oxidize ascorbate and consequently show poor anti-proliferative activity [@pone.0110291-Kalinowski1], [@pone.0110291-Kalinowski3].

Those ligands based on the 7-hydroxyquinolin-8-yl (series **4**) moiety bind iron in an analogous manner to that of 2-hydroxynaphthaldehyde thiosemicarbazone [@pone.0110291-Lovejoy3] or 2-hydroxy-1-naphthaldehyde thiobenzoyl hydrazone (H~2~NTBH; [@pone.0110291-Kalinowski3]) and utilize the *O*,*N*,*S* donor atom set [@pone.0110291-Serda1]. Similarly, those chelators of series **6**, based on the salicylic moiety, also bind iron *via* the *O*,*N*,*S* donor atom set in a similar mannerThe EP was well received, and was nominated for Album of the Year and Best R&B & Soul Album on Korean Hip-Hop Awards and Korean Music Awards, respectively, as well the two track on the album "D (half moon)" and "21" received multiple nomination.

In 2016 he had several collaborations, notably featuring on Taeyeon's single "Starlight", Heize's single "Shut Up & Groove" and "And July", and a collaboration on a single and music video with Zico and Crush, named "Bermuda Triangle", which debuted on Billboard'''s World Digital Songs chart at No. 3, making it the highest position he had received on that chart. He also placed for the first time on two "overall popularity" charts; he and his song "D (Half Moon)" featuring Gaeko debuted at No. 2 on


d’Alembertian system with unit propagation speed (see Proposition \[prop\_gov-Um\]). To a certain extent, the derivation of hyperbolic-type governing equations provides an appropriate formulation which enables systematic investigations of problems related to structure transformations in both theoretical and numerical senses. As a tentative application, it was demonstrated in the previous section that efficient forward solvers are readily implemented on basis of this alternative framework instead of the original model.

More significantly, the transform from an integral equation to partial differential equations also initiates smooth discussions on the corresponding inverse problems by using classical results of inverse hyperbolic problems. In a forthcoming paper, we shall study the problem of identifying the nucleation rate $\alpha(\bm x,t)$ by several kinds of observation data of the generation events $u(\bm x,t)$, for instance, by final measurementsDiversity of Acinetobacter baumannii strains isolated in humans, companion animals, and the environment in Reunion Island: an exploratory study.
Acinetobacter baumannii can be responsible for community-acquired infections in tropical climates like that of Reunion Island. The epidemiology of these community-acquired A. baumannii infections is not well understood. The aim of this study was to characterize A. baumannii strains isolated from patients at the time of admission to the university hospital of Saint-Denis, from environmental samples, and from pets. In this exploratory study, samples were collected by swabbing the rectum and mouth. A. baumannii isolates from positive samples were identified by VITEK 2 system, blaOXA-51-like gene PCR, and partial sequencing of the rpoB gene. Antimicrobial susceptibility testing was then performed. Strains were further analysed by multilocus sequence typing and pulsed-field


Q:

Need a suggestion

I want to make website for a school and because of that I need a suggestion. I'm trying to make a schedule table for each teacher would it be good to set them in one table or in different tables for each teacher(Note: Teachers can change the schedule from the site.)? The schedule table looks like this but in order to include the schedule of all teachers I wanted to add the ID column too.
And the second question about chatting. In order to add the chatting function to my site, I've  opened a new table with name Chats. So the question is would it be good to open different tables for the chats or it would be good if I modify the Chats table eachivec4(5 * m - 2048), greaterThanEqual(m, ivec4(1536)));

        ivec4 decoded = (e << 10) + (mt >> 3);
        // +Inf or NaN are decoded to 0x7bff (max finite value).
        decoded = mix(decoded, ivec4(0x7bff), bvec_or(greaterThan(decoded & 0x7fff, ivec4(0x7c00)), equal(decoded, ivec4(0x7c00))));

        if (decode_mode == MODE_HDR_LDR_ALPHA)
            decoded.a = int(round_down_quantize_fp16(color.a));

        return decoded;
    }
    else
    {
        return round_down_quantize_fp16(color);
    }
}

struct BlockMode
{
    ivec2 weight_grid_size;
    int


weight_mode_index;
    int num_partitions;
    int seed;
    int cem;
    int config_bits;
    int primary_config_bits;
    bool dual_plane;
    bool void_extent;
};

bool decode_error = false;

BlockMode decode_block_mode(uvec4 payload)
{
    BlockMode mode;
    mode.void_extent = (payload.x & 0x1ffu) == 0x1fcu;
    if (mode.void_extent)
        return mode;

    mode.dual_plane = (payload.x & (1u << 10u)) != 0u;

    uint higher = (payload.x >> 2u) & 3u;
    uint lower = payload.x & 3u;

    if (lower != 0)
    {
        mode.weight_mode_index = int((payload.x >> 4u) & 1u);
            mode.weight_grid_size = ivec2(6, 10);
            else if (lo == 1)
                mode.weight_grid_size = ivec2(10, 6);
            else
                decode_error = true;
        }

        int p0 = int(bitfieldExtract(payload.x, 4, 1));
        int p1 = int(bitfieldExtract(payload.x, 2, 1));
        int p2 = int(bitfieldExtract(payload.x, 3, 1));


      mode.weight_mode_index = p0 + (p1 << 1) + (p2 << 2) + (p3 << 3);
    }

    // 11 bits for block mode.
    // 2 bits for partition select
    // If partitions > 1:
    //   4 bits CEM selector
    //   If dual_plane:
    //     2 bits of CCS
    // else:
    //   10 for partition seed
    //   2 bits for CEM main selector
    //   If CEM[1:0] = 00:
    //     4 bitsbitfieldExtract(vd1, 0, d_bits);

    int x0 = (v2 >> 6) & 1;
    int x1 = (v3 >> 6) & 1;
    int x2 = (v4 >> 6) & 1;
    int x3 = (v5 >> 6) & 1;
    int x4 = (v4 >> 5) & 1;
    int x5 = (v5 >> 5) & 1;

    int ohm = 1 << mode;
    if ((ohm & 0xa4) != 0) va |= x0 << 9;
    if ((ohm & 0x08) != 0) va |= x2 << 9;
    if ((ohm & 0x50) != 0) va |= x4 << 9;
    if ((ohm & 0x50) !=


     ret = (cem & 3) * num_partitions + bitCount(bitfieldExtract(uint(cem), 2, num_partitions));
    }
    else
    {
        ret = (cem >> 2) + 1;
    }
    return ret;
}

void decode_cem_base_endpoint(uvec4 payload, int weight_cost_bits, inout int cem, out int base_endpoint_index,
    int num_partitions, int partition_index)
{
    if (num_partitions > 1)
    {
        bool single_cem = (cem & 3) == 0;
        if (single_cem)
        {
            cem >>= 2;
   (hiking): Follows the Willow River in the undeveloped northeastern part of the park, past a glacial mound ().

Willow River Nature Center
The Willow River Nature Center is located near the main picnic area, and features natural history exhibits.  Naturalists offer public programs throughout the year.

References

External links

 Willow River State Park website

Category:1967 establishments in Wisconsin
Category:IUCN Category V
Category:Nature centers in Wisconsin
Category:Protected areas established in 1967
Category:Protected areas of St. Croix County, Wisconsin
Category:State parks of Wisconsin


in order to support grass-roots organisations to increase access to safe abortion. One such organisation which received support under the last round of funding ...

The Safe Abortion Action Fund (SAAF) which is hosted by IPPF was set up in 2006 in order to support grass-roots organisations to increase access to safe abortion. One such organisation which received support under the last round of funding ...

The Safe Abortion Action Fund (SAAF) which is hosted by IPPF was set up in 2006 in order to support grass-roots organisations to increase access to safe abortion. One such organisation which received support under the last round of funding ...

I became a sex worker after a friend advised me that this job can provide me with some income. My husband left me sixWisconsin Democrat Rep. Tammy Baldwin has been named the projected winner in her race against Republican Tommy Thompson. Baldwin's victory makes her the first openly gay candidate elected to the U.S. Senate.

"Tammy Baldwin's victory showed what a majority of Americans already know: that candidates should be judged on their qualifications for the job and not their sexual orientation," said Herndon Graddick, president of the Gay & Lesbian Alliance Against Defamation (GLAAD).

In a recent interview with the Guardian, Baldwin said, "If you are not in the room, the conversation is about you. If you are in the room, the conversation is with you."

She continued, "We never had an openly LGBT member of the U.S. Senate, and even though there are strong pro-equality allies who serve there, it has always


question itself non-trivial; you can look up trivial stuff directly on wikipedia or elsewhere.
If it is anything mentioning "P vs NP", and claiming a result, you are doing it wrong: you should be claiming how your result doesn't make sense, as it would mean a breakthrough, and the question should be to help find the faults. Therefore, always change "check my proof" to "find my error" (and I don't mean just the tags).
Ask the question with humility.
If you edit the question to fix it up, and it changes the meaning of the question too drastically, ask it again. Of course, if the question is bad in other ways aside from your edit, it might just sink again.

A:

I think it has been explained why such posts are not suitablestirring constantly for a few minutes until milk thickens. The floury taste of the corn starch should be gone before you are done.

Remove the mix from heat and chill in fridge overnight.

Next day, mix the sloe gin with the berry mix. Blend 2/3 of the blueberries until smooth and keep 1/3 aside. Mix together the thickened milk, blended blueberries and whole blueberries till well combined.

If you own an ice cream maker:

Transfer the mix into ice cream maker and process according to manufacturers instructions.

If you do not have an ice cream machine:

Freeze the mix, for about 1.5 hours, take it out & scrape/whisk with an electric mixture or with hand till smooth & all the crystals are gone from the mix. Do this for at least 5 times before


you finally freeze in a metal container.

Serve topped with some fresh blueberries. I served the ice cream in little kiddie cones with ice cream scooped with the small melon scoop.

Well by the time you finished reading the post the ice cream melted:-)

What more could I say except that this was declared as delicious by all. The beautiful color & the abundance of berries in every bite, unlike the store bought ice creams were the extras which added to the grading scale. We are still enjoying so berry Blueberry Gelato.

What is Gelato?

Gelato, (plural gelati), is Italy’s regional variant of ice cream. It is made with some of the same ingredients as most ice-creams; milk & cream, sugar, flavorings fruits, nuts, essences, etc. and air are the main ingredients. Unliketransfer your file to us. Please use DropStuff, WinZip or any major compression software to compress the file before you send it. If you do not have compression software installed, visit the Software Downloads area in Resources & Support for additional information.


                     √

The novel miRNAs were numbered sequentially from 1 to 25.

Star sequences were also identified for at least five of the novel miRNAs, supporting the authenticity of the corresponding miRNAs, as their detection is an important criterion for miRNA validation (Figure [6](#F6){ref-type="fig"}). Such star sequences are small RNAs complementary to mature miRNAs, which are produced during pre-miRNA processing, but are not loaded into the RISC complex and are degraded \[[@B1]\]. Indeed, star sequences were not identified for 20 novel low abundance miRNAs, most likely due to their rapid turnover. Most of the new miRNA genes were intergenic rather than intronic, however the novel highly expressed miR_8 was non-conservedin our analysis. This approach was unable to identify candidate targets for some of the novel miRNAs, a result that may be explained by the high stringency of the prediction algorithm because targets of conserved miR_4 and miR_11 were also missed. Alternatively, some of these low abundance non-conserved miRNAs may have appeared recently and do not yet have targets, or misannotation or incomplete annotation of the ZF genome may have prevented identification of such targets.

Star sequences of zebrafish microRNAs
-------------------------------------

Star sequences for 50% of the miRNAs, both known and novel, were also detected and identified (see Additional File [2](#S2){ref-type="supplementary-material"}). This corresponded to 102 star sequences complementary to known miRNAs. Of these, 42 were sequenced previously \[[@B19],[@B20]\] or registered in miRBase and 5 were complementary to the novel miRNAs. As


tried to escape." "The master knew." "He knows everything." "He hunted him and caught him and strapped him to a cross and cut away piece after piece until there was no Theon left." "Good." "If it weren't for you, I'd still have a family." "If I could do what Ramsay did to you right here, right now, I would." "I deserved everything." "I deserve to be Reek." "I did terrible things." "Turned on Robb." "Captured Winterfell." " Killed those boys." " They weren't "those boys."" "They were Bran and Rickon." "They were your brothers." "You'd known them since they were born." "They weren't." "They were only..." "Only what?" " I can't." " Tell me." "I can't, not unless the master says." " Tell me." "They weren't what?" "for six months." "We are more prepared for a siege than they could ever be." "All we have to do is wait for them to freeze, starve, and mutiny." "You disagree?" "Stannis isn't from the North." "You are, Father." "I think you're missing an opportunity to show the people of the North how House Bolton treats southern invaders." "And what do you recommend?" "That we not sit and wait for Stannis to decide what sort of fight this is going to be." "That we hit first and hit hard and leave a feast for the crows." "A smart commander does not abandon a defensive advantage." "As long as we stay behind these walls, they can't touch us." "Not to mention that the snow is so deep, we couldn't


Ash HN: Suggestions for Good Resources for Investing - harshamv22
I would love to understand economics and build knowledge around investing. Please suggest some good resources around economics and investing (stocks, companies etc.)
======
shoo
A reasonably sound place to start for investing as an individual is the
Bogleheads wiki:
[https://www.bogleheads.org/wiki/Main_Page](https://www.bogleheads.org/wiki/Main_Page)
The general Bogleheads approach isn't to try to estimate value of individual
stocks or sectors of the economy, basic idea is passive investment: buy & hold
index funds to get diversified exposure to market returns, then minimise costs
by avoiding funds with high management fees. Bernstein's
[http://www.efficientfrontier.com/](http://www.efficientfrontier.com/) is good
reading, from perspective of individual investor.

If on the other hand you want to learn about how to estimate value of
companies (this will probably will not have a good return on time or money
invested for an individual compared to low effortspecific steps. Once you have CrossOver installed and running you can come back to this page and click the Step 2 button, or follow the manual installation guide, to begin installing your Windows application.

Well there are a few things I look for (I will produce a bonus video about this topic and add it to the other bonus video tutorial) but basically I like to see sites like forums/niche sites/Q&A sites in the top 10 along with other things like sites that are not targeting exact keyword in title/meta, sites with low page authority and domain authority, sites that are less than 3 years old etc etc

Finding the best keyword research tool also depends on your own experience with SEO subjects such as buying keywords, long tail content,


just as diverse.No special rules apply to them, but they do get to purchase Social Standing normally – the other races interact differently with the Social Standing Tiers.

SpritesThe Sprites are a race of usually small growth, usually living in proximity to various expressions of nature, such as trees, ponds, and streams, but also caves and other such. Depending on their origin, they may exhibit various different physical traits and abilities.Being relatives to spirits of the elements, the Sprites are inherently magical, naturally gifted with a special art of Transfiguration that all Sprites are privy to, making them uniquely skilled craftsmen.Some Sprites expand on their magical abilities: they may pick up the Ghost Hand, a common trick among Sprites, or they may be training in the art of Glamoursize, a Sprite's Brawn is limited to 3.

-Social Standing Limitations:Sprites who take Social Standing above Tier 3 (High Freeman) are limited to the T3 trappings and cashout. However, their Sprite magic Trait is upgraded (after upgrading it with trait points normally), beyond the maximum of 3d: T4 gains +1d. T5 gains +2d.

Todo: defining the specific origins and the additional traits as mentioned in the fluff text above.

TrollsTrolls are made what they are by their absurd Toughness, both physical, but also in spirit. Perhaps, this is why these harsh folks chose to live in similarly harsh places: in the depths of bogs, high atop mountains, underground in tunnels, or in the cold desert nights.Trolls have a peculiar physique, in that throughout their lives, they never cease growing, and seem


Compass Reset as a way to help other women who are suffering from the same kind of loss. According to Grief Coach Ursula, there was a time, a very long time, when she floundered, a time when even normal daily activites seemed impossible. While there were lots of resources available, few spoke to her and what she believes is the grieving heart that is unique to a mom.

She never believed that she would ever find happiness or be happy again. In fact, she felt the very idea of happiness to be an insult to her daughter and her memory. But she now knows that mindset was actually the opposite of what Kelli would have wanted and the opposite of what she would have taught her if she wasstill alive. According to Coach Ursula, someday, as hard as it might be to believe right now, a happy, meaningful life after the death of your child is possible.

Ursula is a graduate of Fowler International Academy (FIA) as a Professional Certified Coach. She is a graduate of the University of Phoenix and has a BS in Business Management she has combined her love of business with that of public speaking and has educated thousands of high-school and college-aged students about the joy of philanthropy and the importance of becoming organ donors. She has over 20 years business management, accounting and consulting experience. She is married to her long-time sweetheart, Kevin, and is the mother of three children, Tristan, Kelligar(deceased) , and Aidan.


human endeavor? Even dying?

Adam Smith, who lauded the efficiency of capitalism, would answer
"yes." Why not include dying as part of the Gross Domestic Product --
one addition to the Wealth of the Nation?

Within the past five years, hospice has joined up in the army of
capitalism -- one more listing on the Dow-Jones. It is not a bad
investment. Since the ultimate mortality rate is 100%, hospice is
assured a stream of customers. People, moreover, die at home -- no
expensive hospital tab. And insurers will pay. Thirty years ago
Medicare crafted a hospice benefit: If patients with "terminal"
illnesses abandoned expensive and futile heroic medical wizardry,
Medicare would pay for all the palliative care the patient might need
-- including nursing care, physicians, medications and homemakers.
Medicare money was a boon to struggling hospices, forced to relyA non-profit
Blue Cross plan may have a few for-profit subsidiaries. The nursing
home industry has always divided into non-profits and for-profits. As
for home care, forty years ago the non-profit Visiting Nurses
dominated -- but, with Medicare reimbursement making this market more
attractive, the profit-driven agencies, particularly the mega-chains,
rushed in.

The sometimes Jesuitical distinction between for-profit and
not-for-profit does not necessarily signal poor care. One study
comparing for-profit and not-for-profit hospices faulted the latter
-- but, anecdotally, patients have not registered complaints. The
staff at both kinds of hospices -- the physicians, nurses, social
workers and chaplains -- hold dear their professional commitment to
patients.

Yet in the long run this one last step in the capitalization of
health care is troubling. The hospice model is built on teams of
caregivers. Will accountants now sit at the table, discussing the
costs of the


Q:

How to add headers to slumber in python?

I'm trying to send a request to parse.com's REST API. According to parse's documentation I need to put the App ID and API Key on the request.
I tried to do this using slumber but I keep getting
    Client Error 401: http://api.parse.com/1/installations/
What is the proper way to add headers to slumber? I tried following the docs http://slumber.readthedocs.org/en/latest/options.html#custom-session-objects but it seems to be outdated and even after some modifications, it still didn't work.
For reference, here is my code:
session = requests.Session()
session.headers = {"X-Parse-Application-Id": APPLICATION_ID, "X-Parse-REST-API-Key": API_KEY}

api = slumber.API("http://api.parse.com/1/", session=session)
api.installations.get()

EDIT:
Instead of X-Parse-REST-API-Key, it's actually X-Parse-Master-Key

A:

I think best way to do this is to use a custom Authentication class http://slumber.readthedocs.org/en/latest/options.html#specify-authentication:
import slumber
from requests.auth import AuthBase

class ParseAuth(AuthBase):
    def __init__(self, app_id, api_key):
 come and see me." "Will you take it easy?" "Your health comes first." "No, the championship comes first." "That's why you're here, MacGyver." " And I appreciate it." " Hey, whoa." "We're down to a two-game season." "We got to win both." "Right, and Derek's our only chance." "You're the coach now." "You have to do something with him." "How about canning him for starters?" "For every goal he scored, he spent four to six minutes in the penalty box." "What did you see in him to think he was Olympic material?" "I saw the next Gretzky, maybe better." "He's got that fire inside him, something that can make him a champion." "That same something you took to the Olympics in 1 960?" "I see a little bit


[Localized benign pleural mesothelioma].
Benign mesothelioma of the pleura is a very rare tumor. The cells responsible originate from either the mesothelium or the submesothelium. This is why such tumors are described in the literature as fibroma of the pleura, mesothelial fibroma, localized fibrous mesothelioma and monophasic spindle cell tumor. Their growth, is very slow taking several years or even decades. In contrast to the more common malignant mesothelioma of the pleura, it is not related to asbestos exposure. This report deals with a 47-year-old woman patient with a giant benign mesothelioma of the pleura in the region of the right thorax, which was completely removed by thoracotomy.(and may even pay for) one you’re discarding. Try that with an old vinyl or composite fence!

Inevitably, chain-link fencing possesses a utilitarian aesthetic, but style options exist. Different mesh sizes and wire gauges are available, and the polymer coatings now come in colors, such as brown, green, and black (any of these provides a softer look than silver). When installed among shrubs or along the border of wooded areas, it’s possible for a chain-link fence to be nearly invisible, especially if outfitted with fabrics or lattice panels.

Bob Vila is the home improvement expert widely known as host of TV’s This Old House, Bob Vila’s Home Again, and Bob Vila. Today, Bob continues his mission to help people upgrade their homes and improve their lives with advice online at


BobVila.com. His video-rich site offers a full range of fresh, authoritative content – practical tips, inspirational ideas, and more than 1,000 videos from Bob Vila television.

Note: The views and opinions expressed in this article are those of the author and do not necessarily reflect the opinion or position of Zillow.something that hacktivists in general do. As a member of this group then why has this gotten you so angry that someone has dared to hack into private data?

LN: The Chaos Computer Club is an organization that respects citizen’s private rights and I can tell you any hacker will go to jail for far less than what we are seeing on German grounds here. So I try to correct this image of the evil hacker. I also want to remind you of what we do every day by helping people to protect their systems. So the knowledge about computer security weakness is not necessarily the motivation to actually exploit this, but it can also be pursued by the motivation to close this in order to protect citizens better.

RT:


at turning visual thoughts into real designs.

A:

If you need ways to come up with more ideas, then check out the post referenced in the comments.
If the question is more about having ideas and getting them turned into reality, well, this is a big challenge of being a designer.
Sketch out your ideas. Get them out of your head and onto paper or on the screen. Do it with the mindset that the sketches can be quick and rough. This archives your ideas and helps you start to develop the idea further.
If executing ideas is a problem for you, you'll find that getting better takes practice. If you want to get better at math, you learn about math and then solve math problems. So if you want to getQ:

Alamofire always give me error with status code 500 in response

I'm facing the following problem, I'm trying to use Alamofire to access to a few Web services in my application, this is the code that i'm using:
Alamofire.request(.GET, "https://httpbin.org/get")
        .validate()
        .responseJSON { response in
            switch response.result {
            case .Success:
                print("Validation Successful")
            case .Failure(let error):


He became friends with Theodore Roosevelt, who was a member of the council of police commissioners which governed the NYPD. Fluent in several Italian dialects, Petrosino was able to 'make' cases that other officers could not. His ability to solve crimes in the Italian community was such that whenever a serious crime took place in that area, his superiors would call out, "Send for the Dago!"

On July 20, 1895, Roosevelt promoted him to detective sergeant in charge of the department's Homicide Division. The pinnacle of his career came in December 1908 when he was promoted to lieutenant and placed in charge of the Italian Squad, an elite corps of Italian-American detectives assembled specifically to deal with the criminal activities of organizations like the Mafia, which Petrosino saw as#ifndef SRC_NODE_METADATA_H_
#define SRC_NODE_METADATA_H_

#if defined(NODE_WANT_INTERNALS) && NODE_WANT_INTERNALS

#include <string>
#include "node_version.h"

namespace node {

// if this is a release build and no explicit base has been set
// substitute the standard release download URL
#ifndef NODE_RELEASE_URLBASE
#if NODE_VERSION_IS_RELEASE
#define NODE_RELEASE_URLBASE "https://nodejs.org/download/release/"
#endif  // NODE_VERSION_IS_RELEASE
#endif  // NODE_RELEASE_URLBASE

#if defined(NODE_RELEASE_URLBASE)
#define NODE_HAS_RELEASE_URLS
#endif

#define NODE_VERSIONS_KEYS_BASE(V)                                             \
  V(node)


Scars And Stripes: Assassin’s Creed III

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There are three remarkable things about the new Assassin’s Creed III trailer, although ‘remarkable’ may be too strong a word really, so let’s dial it back to ‘notable’. Thing number one is that, having just read all about Rome II, I couldn’t help but think the opening of this video would make more sense as an advert for Total War of Independence. Secondly, I was surprised to learn that despite not actually being released yet, Assassin’s Creed III was the best adventure game and action game at E3. It was also the best trailer, which makes more sense. The last thing I noted was that some of the single player missions are so big that it’s only possible for consolemen to getmethacholine will also be assessed. The second specific aim is to determine whether vitamin C can attenuate the ability of ozone to enhance responsiveness to allergen challenge after ozone. Subjects (n=10) will be given vitamin C (500mg X 4/d) or placebo for 3 days before ozone exposure. The level of cellular chemiluminescence and plasma Trolox equivalent antioxidant capacity will be determined before and after ingestion of vitamin C. Allergen challenge will again be conducted 18 hours following ozone exposure. This study's overall goal is to determine whether baseline oxidative state is a useful marker of risk for asthma exacerbation by oxidant pollutants, such as ozone.


By Andy Rowell

It may be a New Year, but there is an old oil spill that keeps on spilling. The trouble is that you will probably have never have heard about the spill.

But you need to know. Because, for more than 14 years, some 10,000 to 30,000 gallons of oil have leaked daily from a sunken oil rig owned by Taylor Energy into the Gulf of Mexico, about 12 miles south of the mouth of the Mississippi River.

The disaster began way back in September 2004, when the company's oil platform, known as MC-20 Saratoga, was destroyed by Hurricane Ivan. Although the company contained some of the pollution caused by the loss of the platform, it did not stop all the leaks.

Unless the oil spill is stopped, the sunkenrig could carry on leaking for 100 years, becoming America's worst environmental disaster. Even now, if you take the high end of the leak estimate, the site may have released an estimated 150 million gallons of oil. This is silently creeping towards the estimated 200 million gallons spilled by BP during the Deepwater Horizon oil spill in 2010.

Back in November last year, the U.S. Coast Guard directed Taylor Energy to implement a new containment plan which "must eliminate the surface sheen and avoid the deficiencies associated with prior containment systems." In theory the company could be fined $40,000 a day for failing to comply.

As you would expect, the company responsible for the spill, Taylor Energy not only disputes the figures concerning the leaks, but even whether it is


in Greater Manchester north of Gloucester. On September 16th, many people in those cities reported a loud, pulsating noise that lasted for five minutes. Some said the noise sounded like it was moving across the sky. Others described it as a low frequency, pulsating bass tone. All of those traits make this boom baffling. Nearby Beetham Tower, the 47-story Manchester skyscraper, is known to create an intermittent hum in windy weather but conditions weren’t right and the sound didn’t match. One witness proposed a link to the earthquake in Chile, which happened at about the same time. No official explanations have been given to date.

Did the mysterious noise then cross the Atlantic? Residents of Oliver in British Columbia heard a loud noise at 3 a.m. on September 18th.other-sports

Updated: Jun 14, 2017 08:37 IST

Former world champion Viswanathan Anand beat Fabiano Caruana of United States in the sixth round to register his first win of the Altibox Norway chess tournament.

Having lost two and drawn three, Anand was under pressure to find back his winning ways and the Indian ace did that in style at the expense of Caruana who suffered his first loss in the tournament.

Anand moved up to 2.5 points out of a possible six and two white games out of the remaining three rounds might just help him recover more.

Armenian Levon Aronian was the other winner of the day, accounting for a rather out-of-sort Vladimir Kramnik of Russia while world champion Magnus Carlsen of Norway remained winless for the sixth day running as he was


masks.

"We supply the products that you might need if you were injured on the job, so we serve the worker’s comp marketplace nationwide, with a focus on Connecticut because that’s where we’re based, but we also have concentrations of business in Texas, Florida and California."

Usually when I profile a small business, I go to visit their premises, take a look at the shop floor in action, and meet the people working there.. so why are we in a Starbucks?

"We’re largely virtual. We have a very small warehouse where we stock goods. But I’m a big fan of technology and we’re really fortunate that the technology today allows us to be very decentralized. We can have people that work in their jammies all hours of the day and they’rein buying trips--those are the entrenched attitudes that you find in big companies."

VidaCura has the state of Connecticut as a customer and also several towns within the state. In fact the state has an explicit set-aside policy favoring Connecticut based contractors whose revenues are less than 15 million dollars a year.

"The bureaucracy runs wide and deep there, and I really believe that they’re interested in doing a good job and I believe they’re looking to save taxpayers money, but on a daily basis it’s often just hard for them to get out of their own way in order to be able to do that."

Berk says that 2010 was a good year for VidaCura and he’s bullish about 2011. He believes the ultimate weapon of a small business like


Criteria* {#os12740-sec-0008}
-------------------------------

The exclusion criteria are: participant suffered from severe spinal degeneration or severe irreversible damage of multiple spinal columns such as spinal tuberculosis and tumor.

*Ethics Statement* {#os12740-sec-0009}
------------------

This study was conducted based on the principle of voluntary participation and was in accordance with the protocols proposed by the committee of our hospital. The patient involved in this study signed written informed consent prior to the study. The participant knew well about the study prior to the experiment and had the capability to complete all plans (Table [1](#os12740-tbl-0001){ref-type="table"}).

######

Unit attribute of lumbar L~3~--L~5~ finite element model

  Component             Type                  Elements foraminoplasty); the ROM of L~4/5~ was 4.6°, 3.2°, 3.4°, 3.4°, 2.9°, 2.9° under the six conditions of M3 (Model 3,Three‐dimensional FE model after basement foraminoplasty) (shown in Table [4](#os12740-tbl-0004){ref-type="table"}, Fig. [3](#os12740-fig-0003){ref-type="fig"}).

######

The ROM of L~4/5~ segment after different parts of formation on L~5~ facet joint (°)

  Model   Condition
  ------- ----------- ----- ----- ----- ----- -----
  M1      4.6         3.2   3.4   3.4   2.8   2.8
  M2      4.6


   3.5   3.5   3.5   3.3   3.0
  M3      4.6         3.2   3.4   3.4   2.9   2.9

![It shows the comparison of the ROM of L~4~/L~5~ segment in the M1 against M2 and M3 under a torque of 7.5 Nm in flexion, extension, left bending, right bending, left rotation and right rotation. According to results obtained by our study, for extension, M2 increased the ROM of L~4~/L~5~ segment by 9.4%, while the ROM of M3 little changed. In left axial rotation, M2 and M3 increased the ROM of L~4~/L~5~ segment by 7.14% and 3.6%, respectively. In right axial rotation, After foraminoplasty performedon the tip facet, M2 notably increased the ROM of L~4~/L~5~ segment by 17.9%, and this was the largest increase at L~4~/L~5~ motion segment among all loading cases.](OS-12-1277-g003){#os12740-fig-0003}

The ROM of L~3/4~ were 3.9°, 3.3°, 3.5°, 3.5°, 2.7°, and 2.7°, respectively, under the six conditions of flexion, extension, left and right bending, and left and right rotation of M1 (Model 1, The intact L~3~--L~5~ FE model); the ROM of L~3/4~ were 3.9°, 3.4°, 3.5°, 3.5°, 2.8°, and 2.8°, respectively, under the six conditions of M2 (Model 2, Three‐dimensional FE model after tip foraminoplasty); the ROM of L~3/4~ under the six conditions of M3 (Model 3, Three‐dimensional FE model after basement foraminoplasty) were 3.9°, 3.4°, 3.5°, 3.5°, 2.8°, 2.8°, respectively (Table [5](#os12740-tbl-0005){ref-type="table"}, Fig. [4](#os12740-fig-0004){ref-type="fig"}).

######

The ROM of L~3/4~ segment after


for extension, M2 increased the ROM of L~4~/L~5~ segment by 9.4%, while little changed in the ROM of M3. In left axial rotation, M2 and M3 increased the ROM of L~4~/L~5~ segment by 7.14% and 3.6%, respectively. In right axial rotation, after foraminoplasty was performed on the tip facet, M2 notably increased the ROM of L~4~/L~5~ segment by 17.9%, and this was the largest increase at L~4~/L~5~ motion segment among all loading cases. This is similar to *in vitro* results reported by Abumi *et al*.[^13^](#os12740-bib-0013){ref-type="ref"} where ROM increased significantly for axial rotation, and increase in ROM occurs in opposite direction for axial rotation. Our predicted results also show similar behavior in axial rotation. Our model predicted that base‐facet foraminoplasty also had less impact on the IDP of L~4~/L~5~antioxidants \[[@B6-microorganisms-08-01095]\] and even probiotic microorganisms \[[@B7-microorganisms-08-01095],[@B8-microorganisms-08-01095],[@B9-microorganisms-08-01095]\].

Probiotics are defined as "live microorganisms which when administered in adequate amounts (10^8^−10^9^ CFU/day) confer a health benefit on the host" \[[@B10-microorganisms-08-01095]\]. The major bacterial strains showing probiotic properties are lactic acid bacteria (LAB) from *Lactobacillus* and *Bifidobacterium* spp., which have been accorded the Generally Recognized as Safe (GRAS) status. The various health benefits documented for probiotics include suppression of obesity and type 2 diabetes through modulating glucose metabolism and prevention of liver disease, as well as suppression of hypercholesterolemia and cardio vascular disease through modulating total cholesterol, LDL-cholesterol and triglyceride metabolisms \[[@B11-microorganisms-08-01095]\]. Other health disorders, such as allergic inflammation and atopic dermatitis; colon, bladder and cervical cancers; inflammatory bowel disease; diarrhea; lactose intolerance; renal diseases; hormonal immune response failure and poisoning


Type Collection (strain CECT 4063, University of Valencia, Valencia, Spain) was selected as a probiotic microorganism in this study due to its potential effect against the infection caused by *Helicobacter pylori* and its ability to adaptat to the apple solid matrix \[[@B8-microorganisms-08-01095]\]. Revival of the lyophilized strain was carried out in MRS Broth at 37 °C, following supplier's recommendations. Then, the stock culture was plated on MRS Agar and incubated at 37 °C for 24 h. During the experiments, the plates were stored at 4 °C. When required, the white layer grown on the surface of each plate was collected in a test tube containing 9 mL of sterile MRS Broth and was further incubated at 37 °C for 24 h in order to obtain inoculums with aexpressed as mg of Trolox equivalents (purity ≥ 97%, Merck KGaA and affiliates, Darmstadt, Germany) per gram of dried sample by comparison with a standard calibration curve prepared in the range between 100 and 300 ppm (y = −0.0014x + 0.4949; R^2^ = 0.9981).

### 2.3.3. Color Measurements {#sec2dot3dot3-microorganisms-08-01095}

Optical properties of apple samples were measured on a black background with a spectrocolorimeter (Minolta, CM-3600d), using D65 as illuminator and as 10° observer. Color measurements were given in CIE L\*a\*b\* coordinates, where L\* is the lightness that varies from black (0) to white (100), a\* is the green (−) to red (+) color component and b\* is the blue (−) to yellow (+) color component.

### 2.3.4. Mechanical Properties {#sec2dot3dot4-microorganisms-08-01095}

Mechanical properties of apple samples were evaluated by means of a puncture


test in a TA-XT Plus texturometer (Stable Micro Systems, Godalming, United Kingdom). The test was carried out with a 2 mm diameter stainless steel cylindrical probe (Stable Micro Systems, Godalming, United Kingdom) that passed completely through the sample at a rate of 2 mm/s. From the force vs. distance curves provided by the equipment, the maximum force (*F*~max~, in N) and the distance travelled by the punch to reach the maximum force (*d*~max~, in mm) were obtained.

### 2.3.5. Microbial Counts {#sec2dot3dot5-microorganisms-08-01095}

*Lactobacillus salivarius* spp. *salivarius* content in both liquid and solid samples were estimated by serial dilution from 10^−1^ to 10^−6^ with peptone water, inoculation onto MRS Agar and incubation at 37 °C for 24 h. In the case of apple samples, the first dilution was obtained in apublished version of the manuscript.

This research was funded by Generalitat Valenciana, project reference GV/2015/066 entitled "Mejora de la calidad functional de un snack con efecto probiótico y antioxidante mediante la incorporación de trehalosa y la aplicación de altas presiones de homogeneización".

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

![Colorimetric maps (L\* vs. a\* and b\* vs. a\*) of fresh apple (FRESH), vacuum-impregnated apple (VI), freeze-dried apple (FD) and air-dried apple at 40 °C until a final water activity of 0.45 (AD_0.45) or 0.35 (AD_0.35). Mean values of samples impregnated with the different impregnation liquids. Error bars represent


stations, the electronic wafer maps are downloaded into an equipment database to ensure that defective chips will not be packaged.
As further shown in FIG. 1, in an integrated circuit pattern of each dice 5, the input, output, power supply and other terminals of the circuit are formed by multiple metalized contact pads 6, adjacent ones of which are usually deployed in lines along the periphery or margins of the pattern in what is commonly known in the art as a test key pattern. Metal lines or traces 7 electrically connect the contact pads 6 to the circuit elements of the dice 5. The outline of the test key pattern is either square or rectangular, and the marginal locations of the contact pads thereon depend on the circuit configurationcontact pads to be tested on an integrated circuit.
Still another object of the present invention is to provide a probe card having multiple probe needles, the pitch of which may be automatically adjusted depending on the test key pattern or contact pad spacing or configuration on an integrated circuit.
Yet another object of the present invention is to provide a probe card having multiple probe needles, the height of which may be automatically adjusted for a particular application.
A still further object of the present invention is to provide a probe card which prevents the need to fabricate multiple test cards for the testing of integrated circuits having various test key layouts.
Another object of the present invention is to provide an automatically adjustable wafer probe card which includes multiple probe


]. Data for this figure are in S4 Data. https://doi.org/10.1371/journal.pbio.1002573.g004

The journal-level analysis strongly suggests the existence of gender segregation across sub-disciplines. However, many journals are multi-topic and even multidisciplinary, thus they may not accurately represent narrower research topics. To overcome this limitation of the journal-level analysis, we must determine the research topic of each publication at a finer scale. To this end, we use a highly accurate and reproducible topic classification algorithm to identify the topics of publications [35]. We identify a total of 69 topics using the titles and abstracts from the set of 61,116 publications by molecular biology faculty in our database. S3 Table lists the identified topics and the most representative words and journals associated with them.

For the publications in each topic, we calculate thebut excluding the publications of the 5 most prolific scientists for each outlier topic. Strikingly, we find that the characteristics of these topics revert to the mean for the entire discipline. That is, the gender of the most prolific authors determines the characteristics of the topic. We believe that this finding raises an important question: Why females have not been able to succeed in genomics in proportion to their numbers? No female in our dataset made it into the top 10 most prolific scientists in genomics, the first female appearing in 12th place. If genomics was gender blind, and considering that females comprise 26% of the biology researchers in our database, this would be an unlikely situation (p ≃ 0.0095).


Evidence that binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell cultures results in extensive substitution of both adenine and guanine residues.
Primary mouse embryo cell cultures were grown in the presence of [14C]guanine, labeling primarily deoxyguanosine residues in the cellular DNA, or in the presence of [14C]adenine, labeling both deoxyguanosine and deoxyadenosine residues in the cellular DNA. These cultures were subsequently exposed to 7,12-[3H]dimethylbenz(a)anthracene for 24 hr. The DNA was isolated and hydrolyzed to deoxyribonucleosides, and the 7,12-dimethylbenz(a)anthracene:deoxyribonucleoside adducts were separated chromatographically allowing the three major adducts found to be identified as bay-region anti-dihydrodiol-epoxide:deoxyguanosine and :deoxyadenosine adducts and a bay-region syn-dihydrodiol-epoxide:deoxyadenosine adduct. Therefore, in contrast to what is known for benzo(a)pyrene, substantial amounts of deoxyadenosine adducts are formed with the more potent carcinogen, 7,12-dimethylbenz(a)anthracene.                                         Context context) {
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corner of the Cushman Street bridge. There is a riverboat tied up to the north side of the bridge and a...

Title taken from front. View of first snowfall of the season on Front Street in Nome, Alaska, with pedestrians and wagon on street. A photography studio is at right and Lacey Barber Shop and Baths is at left. Photographer's number 1078. Oct. 17,...

Title taken from front. View of Fairbanks, Alaska as seen from across Chena River, with bridge in center of photo. Signs on businesses shown read: "N.C. Co.", "Sargent & Pinska", "The Lacey", "The Senate", "The Eagle", and "Tanana". Also from...

Title from caption. "Fairbanks Alaska from across Chena River. July 25th 1905." Other writings on the photograph: "No. 10385" and "Copyright 1905 By L.E. Robertson." Panoramic photographfollowing headings composed the different sections of the questionnaire:Site and respondent: the first section was used to obtain information on the survey site and the water users group.Social and cultural information: the second part gives information on the survey site communities, their representativeness, and social organization, everyday diseases of children, men and women.Climate context: this part informs on communities' awareness of changing climate, relative risks, observed effects and local adaptation measures, vulnerable population and economic sectors to changes in climate.Livelihood: we used this section to obtain information on communities' source of income, source of domestic energy, available resources to fight against natural disasters, infrastructures for water management.Extreme events: the last section was used to collect information on extreme events frequency, the understanding of these extreme events, the loss


et al. [@CR21]; Domfeh et al. [@CR19]). The presence of mosquitoes is mainly a question of temperatures and humidity. Increased temperatures will increase occurrence of malaria. Crops destruction is increasing the cost of food because it is leading to low yields, food shortage and communities incomes declining (MICCA [@CR50]). Food insecurity due to climate change is reality in the CRB as well as in various geographic areas of Cote d'Ivoire (Yabile [@CR76]).

Various adaptation measures are employed by water users to respond to climate change. The foremost adaptation strategy adopted by the study communities is crop diversification. The advantage of crop diversification is in the compensation of one crop failure by the yield of another crop. Many crops are grown at the same time on the same field. AssociationRCP8.5

:   representative concentration pathways 4.5 and 8.5

SAPH

:   Société Africaine de Plantations d'Hévéa

SPI

:   Standardized Precipitation Index

WASCAL

:   West African science service center on climate change and adapted land use

WEY designed and conducted the survey, analysed the data and wrote the manuscript. BTAG, BD and AA revised the draft paper and they have approved the current version for submission and publication. All authors read and approved the final manuscript.

Acknowledgements {#FPar1}
================

Authors are grateful to the Meteorological and Hydrological Agencies of Burkina Faso and Cote d'Ivoire for providing data. We thank the Reviewers and the Editor for their constructive comments. The German Federal Ministry of Education and Research (BMBF) has funded this research through the West African Science Service Center on Climate Change and Adapted


Are Getting Some Surprising Pushback—From Republicans Bob Dreyfuss

“Our boy can become president of the USA and we can engineer it,” wrote Sater. “I will get all of [Vladimir] Putins [sic] team to buy in on this, I will manage this process.… I will get Putin on this program and we will get Donald elected.” Echoing a line that would later become Trump’s own description of why he and Putin might get along, Sater wrote that the Russian leader “only wants to deal with a pragmatic leader, and a successful business man is a good candidate for someone who knows how to deal.” Sater claimed, “I arranged for Ivanka to sit in Putins [sic] private chair at his desk and office in the Kremlin.”

Sater couldn’t resist adding, “Michael IMonday, March 21, 2016

I recently joined Twitter to grow my ability to advocate and share resources, and I have had several interactions with Ender Wiggin, who wrote an outstanding article about what it is like to grow up with pedophilia and why pedophiles do - and do not - need help. This article was originally found here. Ender Wiggin has also written other articles on the topic of pedophilia.

The only thing I would add to this story is that there are organizations that offer expert guidance and know exactly who to connect a pedophile in your area to the help that they need, and have sex-specific training to know when someone really is a risk to children and when they are not, regardless of mandatory reporting. If you


unless it is cleared. It is also possible for a knowledgeable person to hack wireless networks. While I do not encourage keeping secrets, I recognize that some people struggling with these issues might need added protections. If you are looking for help for yourself but need extra security and privacy for peace of mind, Mozilla with the Blur (formerly known as Do Not Track Me), HTTPS Everywhere, Adblock Plus, and NoScript add-ons will give you privacy and security tools, and they are free. Other options include the use of virtual private networks (VPN), which can sometimes cost money.P.S. -In a related side note, our old pals at Phone Scoop pinged us earlier this morning to let us know they've gone magenta for the day in an act of solidarity. Much love, Phone Scoop! Oh, and now so did Phone Arena, Fitch, and GearBits! Also, myself and some other eds are in on the action.


possible value of *k*has been estimated as 0.89. The Full Width at Half Maximum (FWHM) values measured for \[111\], \[200\], \[220\], and \[311\] planes of reflection were used with the Debye-Scherrer equation ([4](#EEq1){ref-type="disp-formula"}) to calculate the size of the nanoparticles.

Further analysis of the silver particles by Energy-dispersive spectroscopy confirmed the presence of the signal characteristic of silver. [Figure 4](#fig4){ref-type="fig"} shows the Energy-Dispersive Absorption Spectroscopy photographs of derived AgNPs.

All the peaks of Ag are observed and are assigned. Peaks for Cu and C are from the grid used, and the peaks for S, P, and N correspond to the protein capping over the AgNPs. HRTEM images of Ag nanopatrticles derived from the plant extract are shown in [Figure 5](#fig5){ref-type="fig"}. The morphology of the NPs was predominantly spherical, and they*Bacillus subtilis* (spore bacteria) (106 CFU/mL) and incubated at 37°C. Presence of the growth was visibly monitored after 48 hours of incubation.

Tubes in which no visual growth was observed were selected. 5 *μ*L of the content was inoculated on the MH agar plates. The absence of growth on the plates confirmed antibacterial activity. The MIC values of *gentamicin* and *active iodine* were determined in similar manner for comparison ([Table 1](#tab1){ref-type="table"}).

The authors wish to acknowledge UGC for the financial support towards the Major Research Project.

![UV/Vis spectra recorded from the culture supernatant that shows the production of AgNPs after 24 hours of reaction. Inset photograph shows change in colour after adding AgNO~3~, (a) after 5 minutes, (b) after 20 minutes and (c) 1 hour.](BTRI2011-454090.001){#fig1}

![Schematic representation of glycolysis and its reaction with


was known in these times as Eilintone and Ellintone.

Among the persons named in the entry for Old Edlington were among others Aubrey de Coucy, Earl of Northumbria, Ilbert de Lacy, Roger de Busli, Walter D'Aincourt, William 1st Baron Percy and William de Warenne, 1st Earl of Surrey.

Churches

St Peter's Parish Church

St Peter's Church dates from the late 12th century, when the Norman style was becoming Transitional, and it is considered a masterpiece of curious Norman carvings, and has a chancel arch decorated with several rows of chevrons. The upper stage of the tower and the north chapel are Perpendicular. A Norman corbel table runs along the south exterior wall, with a variety of carved figures depicting grotesque beasts and human heads. There is a similar corbel table withPro-Steel Prostate Milking Device

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(2 - -6) + -4.
4
What is -4 + (29 + -29 - (-11 - (3 + -3)))?
7
What is 6 + -3 + (-11 - (-9 + -7) - 8)?
0
0 - -5 - (53 - 63) - 1
14
What is the value of -19 + 37 - (-1 - -5)?
14
(-3 - -1 - -4) + 48 + -33
17
What is the value of (25 - (9 - -12)) + (2 - -1) - -8?
15
Calculate -7 + 1 - (-16 - 12).
22
What is the value of -4 + (46 - 17 - 24)?
1
What is 0 - (10 - 4 - -6)?
-12
What is (-3 + -5 - -3 - -25) + 8?
28
Evaluate (-1 - 0) + -9 + 146 + -106.
30
What is (40 - 45) + (2 - -6 - 0)?
3
What is 3From his predictions about space, to what
will happen on Earth, and the dangerous rise
of AI, join us as we explore Stephen Hawking's
predictions of Earth's future!
Without a doubt, Stephen Hawking is one of
the most famous minds in the history of the
world.
His work in various fields of science helped
us grow in many ways, and despite his medical
condition he continued to push science forward
and given detailed looks at how humanity might
be one day.
He helped push the need for space exploration
in the modern day, warned about the rise of
A.I., talked about various events that could
happen to Earth, and more.
Though he is gone, our need to listen to his
words and predictions has not waned.
8.
The Need To Leave Earth
Stephen Hawking spent a lot of time thinking
not just about Earth, but about space.
He made many


that missed us
by mere hours because of the placement of
the Earth.
So what does that mean on the grand scale?
Simple, it means we have to colonize space,
and Hawking was easily one of the biggest
proponents of that, and he made many points
about colonizing other planets to help us
have more of a reach and thus ensure that
our population isn't solely on one planet.
Though to be clear, he wasn't a fool in thinking
we can just GO to another world and colonize
it:
"We will not establish self-sustaining colonies
in space for at least the next hundred years,
so we have to be very careful in this period."
When he made this statement, the world was
very much anti-space because of the money
we were spending in order to do very little
in terms of space exploration.
But his words resonated withvarious technologies to get us to
travel through space faster.
Such as the Breakthrough Starshot initiative.
Which is designed to send a probe to Alpha
Centauri in a fraction of the time that we
travel through space right now.
6.
A.I.
"Judgment Day is inevitable."
- T-850 Terminator
"The development of full artificial intelligence
could spell the end of the human race".
- Stephen Hawking
It may spell out like a line from a sci-fi
movie, but Stephen Hawking never joked about
the fact that when it came to artificial intelligence,
it could be good and helpful to mankind, but
it could also be one of the things that dooms
us all.
And he was an advocate against making it real
in the way that many sci-fi movies have depicted.
Now, like with the space projects and thoughts
on colonization, Hawking was no fool when
it came to the uses of


one of
the biggest, yet most controversial, elements
going on in our world right now.
Not the least of which is because it's affecting
our world all around us, and yet, there are
many people, including many "big business"
people, saying that it's overblown and not
real.
If it was random people saying it was real,
you could understand the skepticism.
But when people like Stephen Hawking speak
up and say it's real, we really should listen.
What's more, he didn't just say it was real,
he noted that he felt it was the biggest danger
to our world right now.
So much so that we're reaching a tipping point
with it where if we don't do something, it
can't be reversed:
"We are close to the tipping point where global
warming becomes irreversible.
Trump's action could push the Earth over the
brink, to become like Venus, with aways, this change in accessibility mimics the progression we’ve seen in software development as a whole. Over the last 50 years, software development has gradually migrated from “low-level” languages — highly technical languages that closely relate to a computer’s underlying architecture — to high-level languages with significantly lower barriers to entry. Similarly, software deployment has migrated from hosted machines and data centers to cloud-based services, with massive decreases in the time and capital required to deploy a new system.

These changes have not simply made software developers more efficient; they have allowed a much broader set of people to develop software and start software companies. Software bootcamps now train working engineers in a matter of months, and startups can turn ideas into products in a few development cycles.

All of


429 So.2d 1092 (1983)
Billy G. CASH
v.
Virda MAYO.
Civ. 3540.
Court of Civil Appeals of Alabama.
March 30, 1983.
*1093 T.J. Carnes of Carnes & Carnes, Albertville, for appellant.
F.J. Allen, II, Boaz, for appellee.
HOLMES, Judge.
This is a breach of contract case.
Appellant contends that the trial court erred to reversal in determining that appellant was entitled to recover $25 a month for rent past due under the terms of an oral agreement. Additionally, appellant alleges error in the trial court's computation of interest and taxing of costs. We affirm.
The pertinent facts are as follows:
Appellee-plaintiff brought suit against appellant-defendant for breach of contract on a written lease. Under the terms of the lease appellant-defendant agreed to rent approximately fifty acres of farm land from appellee for five years at $1,350 per year. Appellant did notThe Minnesota Vikings' electric offseason and draft have produced a crop of players that experts everywhere are reasonably excited about. Whether they're bloviating on the Cordarrelle Patterson trade or questioning the value of being the first team to select a specialist in the draft, pundits certainly are talking about the smaller-market team from Minnesota, where Minneapolis is home to the 15th largest television market in the United States (although it would be appreciably larger if the TV market was expanded to Iowa and the Dakotas).

One criticism that caught my eye—and one I was thinking about on the first day of the draft—is what the Vikings will do with two new three-technique players and a high-performing but quickly aging pass-rushing defensive tackle currently on the roster.

While I and several


run up.

Most concerns about an explosive first step or getting skinny are not as relevant to Wide 9 ends, simply because of the stance and run up that they take. The transition from speed to power remains an important skill and they need to do it in a way that doesn't lose momentum, but for the most part it creates production where there originally might not be any.

The wide alignment actually makes it somewhat difficult to bounce outside, because tackles and ends don't have the ability to block the defensive ends down. At the same time, however, zone runs to the outside create enormous lanes and it is easy for a defensive end to allow the running back to slip underneath. For the most part, it does aends momentum against tackles still working to set their pass protection, they force the tackles to kick out, testing their agility and balance. With that, they almost always create an isolated block between just themselves and the tackle, leaving him on an island. This makes it an ideal blitzing formation.

Both the defensive ends and the under tackles are tasked with aiming themselves at the point where the quarterback would be if they completed their five-step drop, which is a bit different than some systems that simply find ways to put players in the backfield and make plays themselves.

I'm not so sure that the Vikings have the perfect defensive ends for the system, nor do I think it would maximize sack production if employed in total. Jared Allen isn't


the defense. They do have advantages in making sure they can reduce completion percentages given how closely they can mirror receivers. They will also generally reduce passing windows, so that they can potentially make the quarterback wait longer.

The final advantage of man coverage is the ability to send additional players as blitzers to increase pressure. I'm not so sure this is important, however, as the defense is designed (like the Tampa-2) to create pressure by sending just four rushers.

They will also need to consider the fact that their priorities will in large part be dictated by the Vikings offense and what looks they'll see from their opponents as a result of the scoreboard and time remaining. If the Vikings continue to (and I see no reason why theywe cannot use the inherited #merge! because albeit the algorithm
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Title

Author

Date of Award:

1969

Document Type:

Thesis

Degree Name:

Master of Science (MS)

Department:

Nutrition, Dietetics, and Food Sciences

Department name when degree awarded

Food and Nutrition

Advisor/Chair:

Ruth E. Wheeler

Abstract

A total of 33 common fruit juices and drinks representing 15 different fruits were analyzed for ascorbic acid content by a slight modification of the method of Loeffler and Ponting (1942). The juices ranged from 0.96 to 50.88 mg per 100 ml. The drinks ranged from 2.12 to 66.10 mg. All the citrus juices ranked high in ascorbic acid content. One drink was fortified with sufficient ascorbic acid to contain considerably more vitamin than was found in pure orange juice.

The ascorbic acid values of different forms of orange drinks and pure orange juices were compared. Except for one brand, all of the fortified orange drinks contained less ascorbic acidan agreement with nearby small shop owners who are opposing the store ― or until the government can arbitrate in the event the two parties fail to find an amicable solution. According to the ministry, six small shop owners' federations near the Hanam outlet filed for an arbitration between them and Costco Korea to the Korea Federation of SMEs (K-Biz) and demanded the company halt the opening, saying their businesses would be jeopardized. The Act on Cooperation between Large Enterprises and SMEs allows small shop owners to request a negotiation with large enterprises opening a supermarket or a massive discount store in a region, in a bid to prevent small shop owners from sustaining excessive damage.After K-Biz's review on the issue, the ministry advised Costco Korea to postpone