the isolated guinea pig ileum in a dose dependent manner but little depressed angiotensin II-induced contraction. On the other hand, in in vitro experiment using a synthetic peptide as a substrate, tea-leaf saponin showed almost no inhibitory activity against the angiotensin I converting enzyme (ACE) (IC50 > 10 mg/ml).men wearing suits and earpieces crossed a police line and attacked them.

DC Police Chief Peter Newsham strongly refuted the allegations Thursday, "there's no indication at all that the protesters were a terrorist group."

State Department spokeswoman Heather Nauert would not say whether the United States plans to seek the extradition of the security officials, who returned to Turkey prior to the completion of the investigation, avoiding arrest.

However, she did note that their diplomatic immunity lapsed when they left the country, and they would be subject to arrest if they returned to the United States.

"The charges filed against 12 Turkish security officials sends a clear message that the United States does not tolerate individuals who use intimidation and violence to stifle freedom of speech and legitimate political expression," Secretary of


in 2/15, -3.6, 2369/5?
-3.6
Which is the sixth biggest value?  (a) 5  (b) -146  (c) -1/8  (d) 750  (e) -5/4  (f) -7
b
Which is the fourth biggest value?  (a) -13/32  (b) 0.1  (c) -1.3  (d) -1/3  (e) 3
a
Which is the second smallest value?  (a) 2  (b) -0.3  (c) 5/7  (d) -10295/4  (e) -0.1  (f) 0.1
b
Which is the smallest value?  (a) 21  (b) 2  (c) -5  (d) 337
c
Which is the second biggest value?  (a) 1  (b) -0.1  (c) -224  (d) 5  (e) 283  (f) 10
f
Which is the third biggest value?  (a) 6  (b) 227  (c) 1/2  (d) -5/3  (e)in -4/165, -4, -3/113, -2, -3/4, 36?
-4/165
What is the fifth biggest value in 0.05, -1.3, 2/1263, -4, -4/3, -0.4?
-4/3
Which is the fourth biggest value?  (a) 81  (b) -2/31  (c) -1  (d) -796  (e) -12/13  (f) 0.2
e
What is the second biggest value in 0.3, -20, -4, 3, -3, -13/7, 22?
3
What is the fourth smallest value in -1/50, -1/7, -32, -48?
-1/50
Which is the fourth smallest value?  (a) 184  (b) -0.09  (c) -0.139  (d) 5  (e) 1/4  (f) 1/3
f
What is the biggest value in 2/9, -44, 17/5, -32, -7, -1/3, -2?
17/5
Which is the smallest value?  (a) 38490  (b) -1/5  (c) -7  (d) 4
c
Which is the second smallest value?  (a) 2056  (b) -1/6


is the fifth smallest value in 16, -1/2, 2/15, -1181, -2, -5, -0.2?
-0.2
What is the sixth biggest value in -534, -56, 3/5, 4/9, 2, -0.3?
-534
Which is the third smallest value?  (a) 3/2  (b) 311  (c) -998  (d) -3/11  (e) 3
a
Which is the fifth biggest value?  (a) 33  (b) -2/3  (c) 4  (d) -5  (e) -6  (f) -7/6
d
Which is the fourth biggest value?  (a) -625585  (b) -3/2  (c) 2/5  (d) 5
a
Which is the second biggest value?  (a) 16  (b) -43  (c) 4  (d) -3/944
c
Which is the biggest value?  (a) 0.07  (b) -3.85  (c) -2/5  (d) -0.2  (e) -77  (f) 1  (g) -1
f
What isthis case, namely that the map $$\mbox{MI}(\widetilde{{\Bbb C}^2};r,k) \rightarrow
\mbox{MH}(\widetilde{{\Bbb C}^2};r,k)$$ given by taking the holomorphic part of an instanton connection is a bijection. Therefore, a rank 2 instanton on $\widetilde{{\Bbb C}^2}$ is completely determined by a rank two holomorphic bundle on $\widetilde{{\Bbb C}^2}$ with vanishing first Chern class, together with a trivialization at infinity. The instanton has charge $k$ if and only if the corresponding holomorphic bundle extends to a bundle on $\Sigma_1$ trivial on $\ell_{\infty}$ having $c_2=k.$ We are led to study holomorphic rank two bundles on $\widetilde{{\Bbb C}^2}.$ As shown in [@JA], holomorphic bundles on $\widetilde{{\Bbb C}^2}$ are algebraic extensions of line bundles; moreover, by [@CA], if the first Chern class vanishes, then such bundles are trivial on the complement of the exceptional divisor.

[*Note*]{}: Triviality


form $y^n-x^m,$ $n < m,$ $n$ even for nodes and tacnodes, and $n$ odd for cusps and higher order cusps. We want to show that instanton numbers detect the parity of the smallest exponent. In fact, more is true, instanton numbers detect the multiplicity itself.

Suppose $n_1 < n_2.$ We claim that if $j >n_2$ then ${\bf w}(j,p_1) \neq
{\bf w}(j,p_2).$ In fact, for $n<m$ and large enough $j$ the width takes the value $${\bf w}(j,y^n-x^m)=   n(n+1)/2.$$ Alternatively, by vector bundle reasons we have that ${\bf w}(j,p_1) < {\bf w}(j,p_2).$ The second assertion is easier to show. The holomorphic bundle $E(j,p_1)$ restricts as a non-trivial extension on the $n_1$th formal neighborhood $l_{n_1 }$ whereas $E(j,p_2)$ splits on $l_{n_1 }.$ These bundle therefore belong to different strata ofmodifications, but give quite different results. One can also generalize to hypersurfaces in higher dimensions, using the equation of the hypersurface to define an extension of line bundles.* ]{}

Embedding theorem
=================

[**Proof of Proposition 3.1:**]{}

We want to show that $ (j,p) \mapsto (j+1,zu^2p)  $ defines an embedding ${\cal M}_j \rightarrow {\cal M}_{j+1}.$ We first show that the map is well defined. Suppose $ \left(\begin{matrix} z^j & p \cr 0 & z^{-j} \end{matrix}\right)$ and $ \left(\begin{matrix} z^j & p' \cr 0 & z^{-j} \end{matrix}\right)$ represent isomorphic bundles. Then there are coordinate changes $ \left(\begin{matrix}a  & b   \cr c  & d \cr\end{matrix}\right)$ holomorphic in $z, \, u$ and $ \left(\begin{matrix}\alpha & \beta  \cr \gamma & \delta \cr\end{matrix}\right)$ holomorphic in $z^{-1}, \, zu$ such that $$\left(\begin{matrix}\alpha &


images represent isomorphic bundles if the system $$\left(\begin{matrix}\bar\alpha & \bar\beta  \cr \bar\gamma &
\bar\delta \cr\end{matrix}\right)
= \left(\begin{matrix}\bar a + z^{-j } u^2p'\bar c &
z^{2j+2}\bar b +z^{j+2}u^2(p'\bar d  -\bar a p) - z^2u^4pp'\bar c  \cr
z^{-2j-2}\bar c & \bar d - z^{-j} u^2p\bar c \cr\end{matrix}\right) \eqno (**)$$ has a solution.

Write $x = \sum x_i u^i$ for $x \in \{a,b,c,d,
 \bar a,\bar b,\bar c,\bar d\}$ and choose $\bar a_i = a_{i+2},$ $\bar b_i = b_{i+2}u^2,$ $\bar c_i = c_{i+2}u^{-2},$ $\bar d_i = d_{i+2}.$ Then if $ \left(\begin{matrix}a  & b   \cr c  & d \cr\end{matrix}\right)$ solves (\*), one verifies that $ \left(\begin{matrix} \bar a  & \bar b   \cr \bar c  & \bar d \cr \end{matrix}\right)$ solves (\*\*), which implies that theof it) they’re bringing through. (Credit to Dawson for being carried by both Lyon’s Saints and Dockers).

The great teams have depth that holds up when its vital cogs go down. In 2014, Hawthorn lost Josh Gibson, Sam Mitchell and Brian Lake for 8, 9 and 14 games, and their coach for half the season, and still managed to win 17 games en route to the flag. Down Jarryd Roughead, Luke Hodge, Brad Hill and Liam Shiels, the Hawks still managed to embarrass their (perceived) biggest premiership threat by 46 points in Round 2.

Fremantle have never had that depth, and as it’s being exposed, so are they. In the past, the Dockers would have remained dangerous and competitive through their structures, but even those have fallen apart.

After ranking fourth


in inside 50 differential last season, Fremantle are 17th in that stat through three weeks. Aside from their defensive integrity, Fremantle’s greatest strength in the Lyon era has been their supremacy at stoppages, leading the league in clearance differential by a country mile last year. This year, they’re 11th.

Discussions of structure and positioning are often problematic because we, the public, aren’t privy to exactly what teams are intending to do. What is obvious though (and let me tell you, as a Collingwood fan, it is pretty freaking obvious) is a deficiency in skill execution.

It’s no surprise that the three bottom teams in effective disposal percentage – Collingwood, Fremantle and Port Adelaide – are also arguably the three biggest disappointments of the year to date (don’t worry, I haven’tdo you regret your actions? The Swiss media reported that the prize was worth 100,000 Swiss Francs. Would you consider returning these funds to the Libyan people?”

3. Purges Teachers, Now on UNESCO Board: In November, the U.N. agency for education, science & culture elected Turkey to its executive board—barely one year after President Erodgan summarily fired 100,000 teachers, university deans, academics, judges, and other officials. Erodogan persecuted heroic journalists like Can Dundar and Yavuz Baydar, yet will now be a U.N. judge of press freedom. Turkish propaganda celebrated the win, as reported by UN Watch. 2. Mother of All Rogues’ Galleries: In September, the U.N. Human Rights Council assembled the most despicable single panel of presentersin its 70-year history, legitimized by the presence and speech of a former


completed its review in the spring of 2019 but has yet to release its findings and has not answered questions from survivors, attorneys and members of Congress who want to know why it hasn't shared a final report.

"Our investigation found that the FBI was one of many institutions that enabled Larry Nassar's abuse," said Sen. Richard Blumenthal (D-Conn.), who helped lead an investigation into the Nassar scandal and co-authored a pending bill aimed at reforming the way Olympic sports governance handles abuse claims. "It is past time to see the Inspector General's investigation into federal law enforcement's failures. The survivors deserve answers."

That report is one of many offshoots from the sprawling Nassar case that remain unresolved years after the former doctor was sent to prison.

This week marks the- 4). Let k = 15 - r. Does 3 divide k?
True
Suppose 2*w = u + 1 + 1, 5*w - 35 = -5*u. Is (3 + (-22)/u)*-12 a multiple of 15?
True
Let r(t) = t**3 + 9*t**2 - 6*t - 11. Is 16 a factor of r(-9)?
False
Suppose w - 5*h - 23 = 0, -w - 6 = 3*h + 11. Is 16/6*(-9)/w a multiple of 6?
True
Let m(q) = -q**2 + 2*q - 3. Let w be m(3). Is 20 a factor of (30/(-4))/(w/32)?
True
Suppose 5*n - 3 - 20 = -c, 3*n + c = 15. Suppose -n*r = -5*r. Suppose p - 18 + 0 = r. Is p a multiple of 6?
True
Let x = 34 + -18. Let a = -7 + x. Suppose 2*p -


Inhalation of potentially lethal or incapacitating aerosols presents a real and present danger to numerous individuals. Whether deliberately released in a terroristic venue or through a passive incident, the resulting circumstances can be catastrophic. Inhaling aerosols containing lethal opioids, biological agents, or irradiated particles can cause irreparable harm or death.
Illicit opioids can commonly be fine powders which when disturbed, move through the air as dust-like particles. This lethal dust is easily inhaled. First interactors, such as law enforcement personnel, are often subjected to a serious risk of inadvertently inhaling harmful substances, such as fentanyl, when working to secure a contaminated area. These unintentional fentanyl overdoses can be life-threatening events. Similar unintentional overdoses may occur with other harmful substances, such as methamphetamine.
Law enforcement personnel are at risk of secondary# Copyright (C) 2017 Apple Inc. All rights reserved.
#
# Redistribution and use in source and binary forms, with or without
# modification, are permitted provided that the following conditions
# are met:
# 1.  Redistributions of source code must retain the above copyright
#     notice, this list of conditions and the following disclaimer.
# 2.  Redistributions in binary form must reproduce the above copyright
#     notice, this list of conditions and the following disclaimer in the
#     documentation and/or other materials provided with the distribution.
#
# THIS SOFTWARE IS PROVIDED BY APPLE INC. AND ITS CONTRIBUTORS ``AS IS'' AND
# ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
# WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
# DISCLAIMED.


Q:

Java: Save objects in a textfile? Are there readymade solutions?

I want to save the objects I generated in a program. After restart the App should load automaticly all Objects in an Array. I want to write them in a file and parse them after restart. Are the other smarter possibilities than do it by hand?
Thank you

A:

Yes, the concept you are looking for is called serialization. There's a fine tutorial at Sun here.
The idea is that classes you want to persist have to implement the Serializable interface. After that you use java.io.ObjectOutputStream.writeObject() to write the object to a file and java.io.ObjectInputStream.readObject() to read it back.
You can't serialize everything, as there are things that don't make sense to serialize, but you can work around them. Here's a quote about that:

Theand trying to
  run it in your JVM would make no sense
  at all. Another important point about
  java.lang.Object not implementing the
  Serializable interface is that any
  class you create that extends only
  Object (and no other serializable
  classes) is not serializable unless
  you implement the interface yourself
  (as done with the previous example).
That situation presents a problem:
  what if we have a class that contains
  an instance of Thread? In that case,
  can we ever persist objects of that
  type? The answer is yes, as long as we
  tell the serialization mechanism our
  intentions by marking our class's
  Thread object as transient.

A:

You can use the Berkeley DB PersistentMap class to save


and a $3\times 3$ matrix function $\gamma_*(x,t)$ satisfy $$\begin{array}{llllllll}
\dfrac{\partial}{\partial x} B &= & - (A B \sigma_2 + B \gamma)\sigma_1^{-1}& \dfrac{\partial}{\partial t} B & & = - (A \, B \widetilde\sigma_2 + B \widetilde\gamma)\widetilde\sigma_1^{-1}, \\
\dfrac{\partial}{\partial x} C &=& \sigma_1^{-1}( \gamma C - \sigma_2 C A_\zeta) & \dfrac{\partial}{\partial t} C  & & = \widetilde\sigma_1^{-1} (\widetilde\gamma C - \widetilde\sigma_2 C A_\zeta ), \\
\dfrac{\partial}{\partial x} \mathbb X & =&   B \sigma_2 C & \dfrac{\partial}{\partial t} \mathbb X &  & =  B \widetilde\sigma_2 C, \\
 0 &=& A \mathbb X + \mathbb X A_\zeta  + B \sigma_1 C, \\
\gamma_*& =&  \gamma + \sigma_2 C \mathbb X^{-1} B \sigma_1 - \sigma_1 C \mathbb X^{-1} B \sigma_2,
\end{array}$$ is a Boussinesq vessels. When the operators are bounded the(\lambda I - A)^{-1} B(x)\sigma_1 u(\lambda,x) - \\
\quad \quad - \sigma_1C(x)\mathbb X^{-1}(x) B(x)\sigma_2 u(\lambda,x) = \\
= (\sigma_2\lambda + \gamma + \sigma_2 C(x)\mathbb X^{-1}(x)  B(x)\sigma_1 -\sigma_1C(x)\mathbb X^{-1}(x) B(x)\sigma_2 )u(\lambda,x) - \\
- [\sigma_2 C(x)\mathbb X^{-1}(x) \lambda + \gamma_*(x) C(x) \mathbb X^{-1}(x)] (\lambda I - A)^{-1} B(x)\sigma_1 u(\lambda,x).
\end{array}$$ Using and the definition of $S(\lambda,x)$ we obtain that $$\begin{array}{llll}
\sigma_1 \dfrac{d}{dx} y(\lambda,x) & = [\sigma_2 \lambda + \gamma_*(x)] u(\lambda,x) - \\
& \quad\quad [\sigma_2 \lambda  - \gamma_*(x)] C(x)\mathbb X^{-1}(x) (\lambda I - A)^{-1} B(x) \sigma_1 u(\lambda,x) = \\
&= [\sigma_2 \lambda + \gamma_*(x)] [I - C(x)\mathbb X^{-1}(x) (\lambda I - A)^{-1} B(x) \sigma_1] u(\lambda,x)=\\
&= (\sigma_2\lambda + \gamma_*(x)) S(\lambda,x) u(\lambda,x) = \\
&= (\sigma_2\lambda + \gamma_*(x)) y(\lambda,x).\qed
\end{array}$$ One of the corollaries [@bib:CoddLev] of this Theorem is that the function $S(\lambda,x)$ must satisfy the following differential


\mathbb X_0, A & B_0 & \sigma_1\\
\mathbb C^2 & \mathcal K & \mathbb C^2 \end{array} \right]}$$ be a node, such that $A, A_\zeta$ generate analytic semi groups (or possess “functional calculus”) and $D(A)=D(A_\zeta)$. The **standard construction** of the operators $B(x), C(x), \mathbb X(x)$ from the node $\mathfrak N_0$ is as follows $$\begin{aligned}
\label{eq:StConB} B(x) = \dfrac{1}{2\pi i} \int\limits_\Gamma (\lambda I - A)^{-1} B_0 \Phi^*(-\bar\lambda,x-x_0) d\lambda, \\
\label{eq:StConC} C(x) = \dfrac{1}{2\pi i} \int\limits_\Gamma \Phi(\lambda,x-x_0) C_0 (\lambda I + A_\zeta)^{-1} d\lambda, \\
\label{eq:StConX} \mathbb X(x) = \mathbb X_0 + \int\limits_{x_0}^x B(y)\sigma_2C(y) dy. \end{aligned}$$

\[thm:STConpreVessel\]The collection $$\mathfrak{preV} = {\left[ \begin{array}{cccccccccccccccccc} C(x) & A_\zeta, \mathbb X(x), A & B(x)&  \sigma_1,\sigma_2,\gamma \\
\mathbb C^2 & \mathcal{K} & \mathbb C^2 \end{array} \right]}$$ defined by the standard construction from the node $\mathfrak N_0$ is a prevessel, coinciding with $\mathfrakthe corresponding vector-functions. The positivity of $d\bar\rho^-$ is immediate using on arbitrary integrable ${\left[ \begin{array}{cccccccccccccccccc} v_1(\mu)\\v_2(\mu) \end{array} \right]}$: $$\begin{gathered}
 \int_{\mathfrak R} {\left[ \begin{array}{cccccccccccccccccc} v_1^*(\mu) & v_2^*(\mu) \end{array} \right]} {\left[ \begin{array}{cccccccccccccccccc} d\rho_{11}^- + d|\rho_{12}| &0\\0&d\rho_{22}^- + d|\rho_{12}| \end{array} \right]} {\left[ \begin{array}{cccccccccccccccccc} v(\mu) \\ v(\mu) \end{array} \right]} = \\
= \int_{\mathfrak R} |v_1|^2 (d\rho_{11}^- + d|\rho_{12}|) + \int_{\mathfrak R} |v_2|^2 (d\rho_{22}^- + d|\rho_{12}|) \geq 0.\end{gathered}$$ For the measure $d\bar\rho^+$ we need more computations and the following formula can be shown: $$\begin{gathered}
 \int_{\mathfrak R} {\left[ \begin{array}{cccccccccccccccccc} v_1^*(\mu) & v_2^*(\mu) \end{array} \right]} {\left[ \begin{array}{cccccccccccccccccc} d\rho_{11}^+ + d|\rho_{12}| & id\rho_{12}\\-id\rho_{12}&d\rho_{22}^+ + d|\rho_{12}| \end{array} \right]} {\left[ \begin{array}{cccccccccccccccccc} v(\mu) \\ v(\mu) \end{array} \right]} = \\
= \int_{\mathfrak R} |v_1|^2 d\rho_{11}^+ +\int_{\mathfrak R} |v_2|^2 d\rho_{22}^+ + \int_{\mathfrak R} (\Re v_1+\Im v_2)^2 d\rho_{12}^+ + \int_{\mathfrak R}(\Re v_2-\Im v_1)^2 d\rho_{12}^+


substituted with $B_*(x)$ satisfies the same differential equation. Thus $\mathbb X_*(x)B(x)=B_*(x)$. As a result, we obtain that $$C(x)B_*(x) = C(x)\mathbb X_*(x)B(x) = C_*(x)B(x) = H_0(x).$$ Then the equations $C(x)\mathbb X_*(x) = C_*(x)$, $\mathbb X(x) B_*(x) = B(x)$ follows in the same manner.

\[cor:XxInvertible\] The operator $\mathbb X(x)$ is invertible for all $x\in\mathbb R$ with the inverse $\mathbb X_*(x)$.

[**Proof:** ]{}Notice that from Theorem \[thm:vesselmappings\] it follows that $$\begin{aligned}
 \dfrac{d}{dx} [\mathbb X(x)\mathbb X_*(x)] = B(x)\sigma_2 C(x) \mathbb X_*(x) - \mathbb X(x) B_*(x)\sigma_2 C_*(x) =
B(x)\sigma_2 C_*(x) - B(x)\sigma_2 C_*(x) = 0, \\
\dfrac{d}{dx} [\mathbb X_*(x)\mathbb X(x)] = -B_*(x)\sigma_2 C_*(x) \mathbb X(x) - \mathbb X_*(x) B(x)\sigma_2 C(x) =
B_*(x)\sigma_2 C(x) - B_*(x)\sigma_2 C(x) = 0.\end{aligned}$$ Since $\mathbb X(0)\mathbb X_*(0) = \mathbb X_*(0)\mathbb X(0) = I$, the Corollary follows.

\[thm:VesselFromqOnR\] The vessel, $$\begin{array}{lllllll}
\mathfrak{V} & = {\left[ultimate tool for studying solutions of . A most general Theorem in this connection is to show that if there is an open set $\Omega$, where solution is known to exist, then the operator $\mathbb X(x,t)$ is invertible in this region. Since we use the uniqueness of solutions for ODEs, the set $\Omega$ must be at least simply-connected. On the other hand, we do not want enter into topological difficulties, arising from such a general assumption, so we choose a very important and practical case of a strip. So, if it is known that the solution of exists on $\mathbb R\times [0,T]$, we would like to show that the vessel, which realizes $q(x)$ at $t=0$ will exist on this strip.

The idea of the proof of such a Theorem


functions similar results should be obtainable.

**2.** In the case $q(x)$ is analytic and satisfies $\int\limits_{-\infty}^\infty (1+|x|) q(x) dx<\infty$ [@bib:FaddeyevII] one obtains that the fundamental matrices $\Phi_*(i\mu,x), \Phi_*(-A_\zeta,x)$ are UNIFORMLY bounded, and as a result the operator $\mathbb Y^*(x)$ is uniformly bounded as well. Thus there exists $T = T_x$ - the same for all $x$, so that the operator $\mathbb X(x,t)$ is invertible. It follows that there exists a local solution on $\mathbb R\times[-T,T]$ of the KdV equation , which is a very well known result for the KdV equation [@bib:GGKM; @bib:FaddeyevII].

**3.** These vessel constructions are intimately related to the theory of systems [@bib:Staffans]. Their relations and interplay is left for a future work.

[^1]: In the literature one usually denotes the adjoint of an operators $T$, with respectSmall bowel obstruction: role and contribution of sonography.
The purpose of this study was to determine whether sonography provides additional clinical information in patients suspected of small bowel (SB) obstruction. During a period of 30 months, in a prospective setting, we evaluated with sonography 123 patients suspected of SB obstruction. Sonographic examinations of the entire abdomen were performed with state-of-the-art, real-time, grey-scale equipment. Fourteen patients were labelled 'gassy' and no added information was provided following abdominal ultrasound. Sonography confirmed the SB obstruction in 82 cases with 5 false positives, resulting in a specificity of 82.1 %. Sonographic examinations were negative in 27 cases with 4 false negatives and a sensitivity of 95 %. The accuracy was 91.7 % when the 'gassy' patients were excluded and 81.3 % overall. The


It turns out to be in fantastic shape, both cosmetically and functionally. I brought it in to work on the grounds that it might need a little work, and instead we've been having a great time playing with it. No repair work necessary. A wonderful addition to the collection (and quite appropriate for this site, don't you think?)the universe of Almost Famous, Jerry Maguire and Say Anything is an infinitely humane realm ruled by an endlessly benevolent deity: Crowe himself. It's a world where no existential quandary is so great that it can't be solved by the perfect combination of pop song and dream girl, a world of giddy pop epiphanies and gentle humanism unencumbered by protective irony or sneering cynicism.

In Elizabethtown, all of Crowe's formidable virtues as a filmmaker work against him. His palpable affection for his characters–always one of his most admirable traits–morphs into a kind of pathological emotional neediness. "Love me, love me, love me!" screams every frame and every character. Elizabethtown feels like an X-ray of Crowe's soul set to the soundtrack of his life.

Crowe has never been afraid to go


Sex differences in HAART-associated dyslipidaemia.
Because female sex protects against dyslipidaemia and atherosclerosis in normal subjects, we aimed to reveal potential sex differences in metabolic side-effects of a newly initiated highly active antiretroviral therapy (HAART) regimen, and to relate these changes to endothelial cell activation as measured by levels of circulating E-selectin (cE-selectin). Prospective longitudinal cohort study. Tertiary care centre at a University Hospital. HIV-seropositive male (n = 27) and female patients (n = 13) with a plasma viral load of > or = 10 000 copies/ml and 35 healthy controls were enrolled in the study. All participants were weight stable, free of acute opportunistic infections, and had not taken any protease inhibitors before. Serum levels of lipids, insulin, leptin, and cE-selectin were measured before initiation of HAART, andQ:

Using different e-mail account to send mail

I want to use a Excel macro to send a mail to a company. This mail should consist of a piece of text, a table and then the rest of the text.
In the function below I've compiled some code that works the way I want, but I would like to send the e-mail not from my personal account but from a corporate business account (in the code I refer to the latter as myemailadres@outlook.com). I think I have to use the .SendUsingAccount function, but if I implement it like shown below, the e-mail is send using my personal email account and not the one I specify. Can somebody help?
Sub Test()
Dim rng As Range
Dim OutApp As Object
Dim OutMail As Object
Dim TargetSheet As String
Dim


assessed the levels of PD-1, NKG2D and CD38 on CD4^+^ and CD8^+^ T cells. At baseline, we noted significantly lower levels of PD-1 and NKG2D in MPM vs. control patients on CD8^+^ T cells and significantly higher levels of NKG2D on CD4^+^ T cells. Furthermore, CD38 on CD4^+^ and CD8^+^ T cells was higher in patients when compared with controls. However, there were no significant changes in any of these T cell activation markers were elicited after GC1008 therapy.

Finally, as TGFβ has been implicated in the formation of Tregs and blockade of TGFβ in animal models inhibited their formation,[@R5]^,^[@R43]^,^[@R44] we measured the frequency of circulating CD4^+^ Tregs (marked by expression of FOXP3[@R33]) in the blood of healthy volunteers and MPM patients before and after treatment with GC1008. Inoverall survival times seen in our study is consistent with a growing understanding of immune-based responses, as this pattern has been recently described as characteristic of that seen in vaccines or immune checkpoint blockers.[@R46]^,^[@R47] Second, we were able to detect direct evidence of humoral anti-tumor immune responses. Without a clearly identified tumor antigen in a vaccine setting, it is very difficult to detect specific anti-tumor lymphocyte responses.[@R48] Using a polyclonal immunogene therapy activator (namely, the intratumoral injection of an adenovirus expressing Type I interferon), we have previously quantified the induction of humoral responses against known mesothelioma-associated antigens (i.e., mesothelin, SV40T and WT1) or mesothelioma cell lysates, invariably observing the induction of novel or pre-existing anti-mesothelioma antibodies after immunotherapy.[@R49] A number of other investigators have also used humoral responses


University of Pennsylvania and was funded primarily by the Richard Schulze Family Foundation. The study drug, GC1008, was provided by Genzyme (now Sanofi Oncology).

Eligibility
-----------

Eligibility required: 1) pathologically documented MPM, 2) at least one, but no more than two prior systemic therapies, of which at least one contained pemetrexed, 3) documented progressive disease evaluated by Modified RECIST criteria, 4) ECOG Performance status of 0 or 1, 5) serum albumin ≥ 2.5 mg/dL, 6) normal hematologic, hepatic, renal and coagulation parameters, and 7) ability to understand and give informed consent.

Treatment protocol
------------------

Based upon previous pharmacokinetic studies,[@R17] GC1008 was administered at a dose of 3 mg/kg every three weeks as a one-hour IV infusion. This dose was chosen based on non-human primate studies[@R18] and the data from the previous Phase I trialsamples for detection of TGFβ, platelet factor-4 (PF4), vascular endothelial growth factor (VEGF), CCL-18, and plasminogen activator-1 (PAI-1) levels in CTAD tubes (Becton-Dickinson, Franklin Lakes, NJ) to prevent platelet activation. PF4 is released in significant amounts from platelets as a result of activation and was therefore used as a surrogate marker to assess the quality of samples in which the presence of TGFβ may be due to platelet degranulation related to sample processing.[@R61] Serum markers were collected in SST tubes (Becton-Dickinson) to assess anti-tumor antibody responses (see below), serum mesothelin-related protein (SMRP) levels, osteopontin, hyaluronic acid, matrix metalloprotease-1 (MMP-1), MMP-7, PAI-1, and IL-6. SMRP was measured using an ELISA kit provided by Fujirebio, Inc. (Malvern, PA) All other markers were measured at Genzyme using commercially available ELISA kits.


(MOF) and exhibited outstanding detonation performances (9.02 km·s^−1^ of *D* and 33.6 GPa of *P*), which were comparable to that of Pd(N~3~)~2~. The compound **132** had a high density of 1.939 g·cm^−3^, high decomposition temperature of 213 °C and desired mechanical sensitivities (IS: 12 J; FS: 240 N), which could be a competitive candidate of RDX. These energetic compounds containing dinitromethyl or fluorodinitromethyl group enrich the energetic compound library of pyrazolo\[4,3-*c*\]pyrazoles. Furthermore, their group incorporated two tetrazole groups into DNPP molecule, and synthesized 3,6-dinitro-1,4-di(1*H*-tetrazol-5-yl)-pyrazolo\[4,3-*c*\]pyrazole (**133**) and its ionic derivatives (**133a**--**f**) shown in [Figure 42](#molecules-25-03475-f042){ref-type="fig"} \[[@B146-molecules-25-03475]\]. The physicochemical and energetic properties of these compounds are shown in [Table 19](#molecules-25-03475-t019){ref-type="table"}. These compounds were thermally stable and insensitive to mechanical stimulation. The potassium salt (**133a**) possessed a high thermal decomposition temperaturewin.

Anyway, blame foreigners for being born stronger than us Japanese — self-deprecation justifying exclusion.

Educational woesJuly 17's Zeit Gist discussed the
accusation that secondary school "hair police" tamp down on
non-Japanese kids born with the wrong hair color or texture. Now,
according to the Sunday Mainichi (July 8),
foreigners are disrupting the natural ordure as well. Citing an
"education insider" depicting international marriages as moneymaking
unions, foreign mothers allegedly scrimp so much to send money back
home that children lack basic hygiene. Japan's classrooms are
apparently being inflicted with stinky international children.

"In particular, native speakers who have lived in Japan for more than
10 years tend to have adapted to the system and have become ineffective
as teachers — this is also partly because their English has
become Japanized and is spoken to suit the ears of their Japanese
students."

Familiarity is


to see if that experiment, if that bargain for peace was worth the cost.”

“I believe, from what I’m seeing, it was not worth the cost,” he said. “Israel, the world, did not receive the benefit of the peace that was promised.”

He added, “This should be a warning to us all that we need to be careful that when we bargain for peace there has to be a desire for peace, not just on one side but on both sides. To bargain over the heartland of Israel, the land of Israel’s patriarchs, the land where the Bible was lived – that is land that is too sacred to be bargained over for an uncertain outcome.”the internet compared to those without disabilities. The disabled simply miss out on the benefits that the technology now provides. This has become even more of a concern as the coronavirus outbreak rampages throughout the globe. The pandemic has prompted governments to enforce lockdowns, forcing businesses and services to shift their operations online and people to stay at home more than ever. Imposed social distancing regulations have made life even more challenging for the disabled. With limited access to the internet, they risk becoming more isolated.

Fortunately, this important matter has not escaped forward-thinking ventures like accessiBe. The company looks to promote inclusion and wider web accessibility by making it easy for businesses and site owners to make their sites standards-compliant through artificial intelligence (AI).

Complying with standards

For websites to


de uma vez e elas não tem referencia ficando assim:
           DataSet ds = new DataSet();
           ds.ReadXml(caminho);

           ds.Tables[0];
           //Aqui consigo obter os clientes
           ds.Tables[1];
           //Aqui consigo obter os contatos

Dessa forma não consigo criar as referências, as chaves no bando da relação CLIENTE x CONTATO.

A:

Esta é, a meu ver, a pior maneira de ler um XML. Use XDocument no lugar:
XDocument document = XDocument.Load("clientes.xml");

var clientes = document.Root.Elements("cliente").ToList();
var primeiroCliente = clientes.First();
var contatosDoPrimeiroClienteand 1 × antibiotic/antimycotic. After 10 days, cells were fixed with 99.5% ethanol, colonies were stained with Giemsa solution, and the number of colonies was counted.

Statistical analysis
--------------------

Statistical analysis was performed using SigmaPlot (HULINKS). The results are expressed as means ± S.E. Student's *t* test was used for comparison between two groups. Groups more than three were compared using one-way analysis of variance, after which Fisher LSD test was used. For all analyses, a probability value of *P*\<0.05 was considered statistically significant.

RESULTS {#s2}
=======

To analyze the role of SET in cOSA, 2 cOSA cell lines, POS (primary origin) and HM-POS (established from nude mice lung metastatic site of POS cells) were used \[[@r2], [@r11]\]. The protein levels of SET and PP2A were not significantly different between the POS and HM-POS cells


in the Kingdom of Jerusalem through the Pactum Warmundi. In 1110, Ordelafo Faliero personally commanded a Venetian fleet of 100 ships to assist Baldwin I of Jerusalem in capturing the city of Sidon.

In the 12th century, the republic built a large national shipyard that is now known as the Venetian Arsenal. Building new and powerful fleets, the republic took control over the eastern Mediterranean. The first exchange business in the world was started in Venezia, to support merchants from all over Europe. The Venetians also gained extensive trading privileges in the Byzantine Empire, and their ships often provided the Empire with a navy. In 1182 there was an anti-Catholic massacre by the Orthodox Christian population of Constantinople, with the Venetians as the main targets.

The rise of Venetian powerto the Adda. Although the defeat had turned into a victory, the events of 1509 marked the end of the Venetian expansion.

The Gasparo Contarini book De Magistratibus et Republica Venetorum (1544) illustrates the unique system of government in Venice and extols its various institutions. It also shows the astonishment of foreigners at the independence of Venice and its resistance to Italy's loss of freedom – and at it having emerged unscathed from the war against the League of Cambrai. Contarini suggested that the secret of Venice's greatness lay in the co-existence of the three types of government identified by Aristotle: monarchy, oligarchy, and democracy. In the opinion of Contarini, the Maggior Consiglio was the democratic part, the Senate and the Council of Ten were the oligarchy, while the


lift the siege of Candia with joint action on land with the French contingent and by sea under Mocenigo also turned out to be a failure. The French returned home, and only 3,600 fit men were left in the fortress of Candia. Captain Francesco Morosini negotiated its surrender on 6 September 1669. The island of Crete was ceded, except for some small Venetian bases, while Venice retained the islands of Tinos and Cerigo, and its conquests in Dalmatia.

In 1684, soon after the Turkish defeat in the siege of Vienna, Venice entered an alliance, the Holy League, with Austria against the Ottomans; Russia was later included. At the beginning of the Morean War (1684–99) Francesco Morosini occupied the island of Levkas and set out to recapture the Greek ports.on patrol with you guys" "Paulie, Paulie, Paulie, look... you're far too valuable behind a typewriter." "See, what this malcontent needs is a, is a nickname." "Something we can put in the local paper to raise awareness." "Coming up with a name should be a snap for you." "You mean, something like The Michigan Mischief Maker?" "Boy, you writers are amazing." " It's nothing." "Boy, to come up with just the right turn of phrase you must have to wade through a million stinkers like that?" "You got grit." "He's got grit, Mary." "He's the grittiest." "Hey, Bridge, can I borrow your go-go boots to go with this skirt for that'sixties party everyone s going to?" "What'sixties party?" "Just some lame party, I'm totally gonna blow it off...


" Indeed I did." "As a young man about to embark on life's journey, I was faced with a dilemma..." "Hi, how 'bout Cliff Notes?" "Okay, well, when I graduated college I had to make a decision whether or not I was gonna go to law school, as I always planned, or become a writer." "Which did you choose?" "Anyway, Bridge, what I'm trying to say is: follow your heart." "I followed my heart and I ve never looked back." "That's your advice, follow my heart?" " Well, it's not that'simple." "I can't believe I never thought of that!" "I'mean, I'm always, like, so logical." "Bridget, hey, Bridget." "The Doyles brought this over for you." "They made Donny a video letter and they left some room at thebroke off." "And when I brought em back for a refund, they'd only give me a store credit." "I was all, Yeah, like I wanna buy more of your defects." "And I think we should see other people." "And I totally understand if you wanna tell all your Navy friends that you broke up with me." "Good luck at war and stuff." "Bye." "Dude, I'm sorry." "So, can I call her?" "Hey, Cate, listen to this." "I came up with a couple names for this prankster." "Which do you like better The Lone Eggman or The Neighbor-hoodlum?" "Why don't you try something like The Oakdale Vandal?" "The Oakdale Vandal?" "Who's gonna crack the case, the Hardy Boys?" "You know, you're right, Paul." "The Lone Eggman is gold." "Fine,


bathroom?" "What does that matter?" " You re right." "All that matters is seeing Bridget and winning her back." "She's the whole reason I went AWOL." " AWOL?" "Donny, you re in the military." "This isn't just cutting class." "It's desertion." "They, they shoot people for that!" "I don't care." "I d gladly face a thousand firing squads for Bridget." "I'm gonna have to call your parents." " No, don't do that." "They'll kill me." "No, wait." "Come on now, listen..." "You got pig smell." "I'm serious, Donny." "You have to get back to your dorm before anyone notices you ve gone 'A 'W 'O 'L." "Sir, I know I can make Bridget love me." "Then again, a long stretch in the brig might do you some good."can provide conservative solutions [@delage2010percentile; @xu2007robustness]. Some papers consider bringing prior knowledge of dynamics to robust MDPs, and name such problem distributionally robust MDPs. @xu2010distributionally discuss robust MDPs with prior information to estimate the confidence region of parameters abound, which is a moment-based constraint, and they also show that such distributionally robust problems can be reduced to standard robust MDP problems. @yang2017convex [@yang2018wasserstein] use Wasserstein distance to evaluate the difference among the prior distributions of transition probabilities. However, @yang2017convex’s algorithms are not appropriate for complex situations, because they need to estimate enough transition kernels to approximate prior distribution at each step.

Wasserstein robust reinforcement learning {#wass_robust}
=========================================

In this section, we specify the problem of interest, which is actually a minimax problem constrained by some Wassserstein-based uncertainty set. We start with introducing


transport function. For any two probability measures $Q$ and $P$ over the measurable space $(\mathcal{X},\mathcal{B}(\mathcal{X}))$, let $\Xi (Q,P)$ denote the set of all joint distributions on $\mathcal{X} \times \mathcal{X}$ with $Q$ and $P$ are respective marginals. Each element in $\Xi (Q,P)$ is called a coupling between $Q$ and $P$. Let $\kappa: \mathcal{X} \times \mathcal{X} \rightarrow [0,\infty)$ be the transport cost function between two positions, which is non-negative, lower semi-continuous and satisfy $\kappa(z,y)=0$ if and only if $z=y$. Intuitively, the quantity $\kappa(z,y)$ specifies the cost of transporting unit mass from $z$ in $\mathcal{X}$ to another element $y$ of $\mathcal{X}$. Then the optimal transport total cost associated with $\kappa$ is defined as follows: $$D_{\kappa} (Q,P) := \inf _{\xi \in \Xi (Q,P)}\left\{\int_{\mathcal{X}\times\mathcal{X}} \kappa(z,y) d\xi (z, y) \right \}.$$ Therefore, the optimalThis project involves two programs of research. The goal of the major program is to develop and assess techniques for enhancing the informativeness of child witnesses and for evaluating the credibility of their accounts. Most studies in the research program are focused on the relationship between interviewer style and the quality of information provided by young children. Several studies have confirmed that open-ended questions elicit longer and more detailed responses than more focused questions, regardless of the number of incidents experienced and the language (English, Swedish, or Hebrew) in which the interview was conducted. We have also shown similarities between the types of questions that are likely to elicit accurate and inaccurate information in analog and forensic conexts, thereby strengthening the generalizability of the results obtained in many


as well as children who are reluctant to disclose, are currently under closer investigation as these groups were under-represented in prior studies. In other recent studies, we have shown that mental context reinstatement facilitates recall better than physical context reinstatement. These procedures can be implemented nonsuggestively in forensic settings, so these results are potentially important. The goal of the other program of research is to explore the effects of domestic violence on children who were either victims of physical abuse, witnesses of spousal abuse, both victims and witnesses, or neither victims nor witnesses. A group of children were first assessed in 1988/9 when they were between 8 and 12 years of age. The children, their parents, and their teachers were reinterviewed in 1995 and 1996 and analyses ofgravity field to an extraordinary precision. Scientists use that information to infer Jupiter’s composition and interior structures,” said Shang-Fei Liu, associate professor of astronomy at Sun Yat-sen University in Zhuhai, China, and lead author of the research published in the journal Nature.

Computer models indicated that a head-on collision with a protoplanet - a planet in its formative stages - of roughly 10 Earth masses would have broken apart Jupiter’s dense core and mixed light and heavy elements, explaining Juno’s findings, the researchers said.

This protoplanet, with a composition similar to Jupiter’s primordial core, may have been slightly less massive than the solar system’s most distant ice giant planets Uranus and Neptune and would have become a full-fledged gas giant if it had not been swallowed by Jupiter, Liu said.

Jupiter


     return RedirectToLocal(returnUrl);
        case SignInStatus.LockedOut:
            return View("Lockout");
        case SignInStatus.RequiresVerification:
            return RedirectToAction("SendCode", new { ReturnUrl = returnUrl, RememberMe = model.RememberMe });
        case SignInStatus.Failure:
        default:
            ModelState.AddModelError("", "Invalid login attempt.");
            return View(model);
    }
}

A:

The UserName that you are using as the model name is the one used for identity authentification not the Email.take one campaign at a time.’’

Vice President Biden made headlines in early May when he spoke out about supporting gay marriage on "Meet the Press" before President Obama had the chance to make his own statement. Obama said Biden “got a little over his skis’’ with the early announcement, but Dr. Biden told TODAY that the two have since smoothed things over.

“Joe and Barack, they worked this out,’’ Biden said. “It’s fine. Joe speaks from the heart, and that’s what he did. That’s what I love about him. I know a lot of people aren’t used to that in politicians, and that’s what surprises them.’’

Dr. Biden's son, Beau, is currently deployed in Iraq as a member of the military. The Bidens celebrated the wedding of their daughter, Ashley,


The coarsening of nanoparticles occurs through two fundamentally different mechanisms[@b1][@b2][@b3]: In one mechanism, which is known as coalescence, the crystal sphere grows from migration and coalescence of islands or particles over the substrate surface[@b3][@b4]. The other mechanism, which is known as Ostwald ripening[@b5][@b6][@b7][@b8], is related to the growth by interparticle transport of single atoms[@b3], in which larger particles grow at the expense of smaller particles[@b9]. Its driving force is the difference in chemical potential, which arises from the difference in the radius of the curvature of the droplets or particles[@b8].

Carbon spheres have been intensively studied because of their peculiar properties and promising applications. Carbon spheres can be classified by two groups: hollow spheres and solid spheres. Most research has focused on the synthesis of hollow carbon spheres owinga microwave oven for three minutes, and the growth mechanism of the micro-scale SCSs were investigated by transmission electron microscopy (TEM), selected area electron diffraction (SAED) pattern, field emission scanning electron microscopy (FE-SEM), and Raman spectroscopy. This study revealed that the evolution of micro-scale SCSs is mainly controlled by the Ostwald-ripening process. In regard to the composite scheme with micro- or nano-scale carbon materials, the Ostwald ripening played a significant role in the growth phenomena. For example, it played a role in the growth of catalytic particles in a single-walled carbon nanotube (CNT) forest[@b21][@b22], in the electrochemical growth of metal catalysts supported on carbon[@b23], and in the growth of metal clusters attached to CNTs[@b24]. In addition, the effects of Ostwald ripening of catalytic particles on CNT chirality distributions


of substrate in a low-flux regime. In the evolution of SCSs, the occurrence of the layer-by-layer growth mode is not surprising because large, SCSs become larger by the vapor transport deposition of carbon elements. The island growth mode can be expected when carbon fluxes with higher rates adhere to the surfaces of the growing SCSs because high-rate carbon flux usually causes a deviation from the equilibrium growth state. In this case, heterogeneous nucleation may be prevalent, resulting in the formation of 3D island growth. The third mode, i.e., the mixed mode, can be operated under a carbon flux condition between the two aforementioned extreme cases.

The ostwald ripening process
----------------------------

The growth of micro-scale SCSs through a combination of the island, the layer-by-layer, and the mixed modes was clearly demonstrated onthe basis of the observed microstructure evolution. The Ostwald ripening process is the underlying phenomenon occurring in all cases, governing individual atom transfers, and contributing to the evolution to the larger SCSs. Importantly, the three growth modes ubiquitously and simultaneously operate on the growth of SCSs, following the Ostwald ripening process.

Through the Ostwald ripening process, carbon vapors are transferred from other solid carbon sources. Subsequently, the carbon vapors adsorb onto the sub-micron carbon spheres. Immediately after, the nature of the adsorption of the additional carbon vapors determines the mode, i.e., the island, the layer-by-layer, or the mixed mode. In addition to the microstructure observations, other convincing evidence supporting the operation of Ostwald ripening process is the fact that the carbon structure is disordered in the nano-scale particles but


presented, and programmed to play to the performer's strengths ... the ideal way to make a recording debut." -...continue...
Recording information: Dukes Hall, Royal Academy of Music, London, England (07/07/2008-07/09/2008)....continue...

The meteoric ascent of Vassily Primakov's international career has resulted from a series of competition victories, prizes in honor of his artistry, and his award-winning...continue...
Recording information: Academy of Arts and Letters, New York City (01/13/2011-01/15/2011)....continue...

Nikolai Lugansky, now a household name on the international concert stages, began his recording career in his early twenties for the label Vanguard Classics. This...continue...
Recording information: Doopsgezinde Kerk, Amsterdam, Netherland (01/26/1993-01/28/1993)....continue...

Works: Sergey Rachmaninov: Variations on a Theme of Chopin, for piano, Op. 22; Variations on a theme of Corelli, Op. 42; Transcription of Rimsky-Korsakov's "Flight of the Bumblebee" from "The Tale of the T...
Performers:
Wild, Earl [Piano]

Works:Hope and patience waning on self-driving bill Presented by Freight Rail Works

With help from Brianna Gurciullo, Stephanie Beasley and Tanya Snyder

PROGRAMMING NOTE: Morning Transportation will not publish on Thursday, Nov. 22, and Friday, Nov. 23. Our next Morning Transportation newsletter will publish on Monday, Nov. 26. Please continue to follow Pro Transportation issues here.

Editor’s Note: This edition of Morning Transportation is published weekdays at 10 a.m. POLITICO Pro Transportation subscribers hold exclusive early access to the newsletter each morning at 6 a.m. To learn more about POLITICO Pro’s comprehensive policy intelligence coverage, policy tools and services, click here.

LOSING PATIENCE WITH CONGRESS ON AV BILL: Hope is diminishing in the private sector that the Senate will be able to advance legislation on self-driving cars by the end of the


     } else {
                assert(vir_is_mul(inst));
                inst->qpu.flags.muf = uf;
        }
}

#if 0
uint8_t
vir_channels_written(struct qinst *inst)
{
        if (vir_is_mul(inst)) {
                switch (inst->dst.pack) {
                case QPU_PACK_MUL_NOP:
                case QPU_PACK_MUL_8888:
             c->defs_array_size;
                c->defs_array_size = MAX2(old_size * 2, 16);

                c->defs = reralloc(c, c->defs, struct qinst *,
                                   c->defs_array_size);
                memset(&c->defs[old_size], 0,
                       sizeof(c->defs[0]) * (c->defs_array_size - old_size));


c->cursor.link);
                break;
        case vir_cursor_addtail:
                list_addtail(&inst->link, c->cursor.link);
                break;
        }

        c->cursor = vir_after_inst(inst);
        c->live_intervals_valid = false;
}

/* Updates inst to write to a new temporary, emits it, and notes the def. */
struct qreg
vir_emit_def(struct v3d_compile *c, struct qinst *inst)
{
        assert(inst->dst.file == QFILE_NULL);

        /* If we're        prog_data->vpm_output_size =
                        align(prog_data->vpm_output_size, 2) / 2;
        }
        assert(prog_data->vpm_output_size <= 16);
        assert(prog_data->simd_width != 2);

        prog_data->out_prim_type = c->s->info.gs.output_primitive;
        prog_data->num_invocations = c->s->info.gs.invocations;
}

static void
v3d_set_fs_prog_data_inputs(struct v3d_compile *c,
                            struct v3d_fs_prog_data *prog_data)
{
        prog_data->num_inputs = c->num_inputs;


   struct v3d_fs_prog_data *prog_data)
{
        v3d_set_fs_prog_data_inputs(c, prog_data);
        prog_data->writes_z = c->writes_z;
        prog_data->disable_ez = !c->s->info.fs.early_fragment_tests;
        prog_data->uses_center_w = c->uses_center_w;
        prog_data->uses_implicit_point_line_varyings =
                c->uses_implicit_point_line_varyings;
        prog_data->lock_scoreboard_on_first_thrsw =
                c->lock_scoreboard_on_first_thrsw;
}

static void
v3d_cs_set_prog_data(struct v3d_compile *c,
                     struct v3d_compute_prog_data *prog_data)
{
                            glsl_vector_type(GLSL_TYPE_UINT,
                                                 glsl_get_components(var->type));
                }
        }
}

static void
v3d_nir_lower_fs_early(struct v3d_compile *c)
{
        if (c->fs_key->int_color_rb || c->fs_key->uint_color_rb)
                v3d_fixup_fs_output_types(c);


  void *debug_output_data),
                      void *debug_output_data,
                      int program_id, int variant_id,
                      uint32_t *final_assembly_size)
{
        struct v3d_compile *c;

        for (int i = 0; true; i++) {
                c = vir_compile_init(compiler, key, s,
          return v3d_return_qpu_insts(c, final_assembly_size);
}

void
vir_remove_instruction(struct v3d_compile *c, struct qinst *qinst)
{
        if (qinst->dst.file == QFILE_TEMP)
                c->defs[qinst->dst.index] = NULL;

        assert(&qinst->link != c->cursor.link);

        list_del(&qinst->link);
        free(qinst);

        c->live_intervals_valid = false;
}

struct qreg
vir_follow_movs(struct v3d_compile *c, struct qreg reg)
{
        /* XXX
        int pack = reg.pack;

        while (reg.file == QFILE_TEMP &&
               c->defs[reg.index]


  }

        uint32_t uniform = c->num_uniforms++;

        if (uniform >= c->uniform_array_size) {
                c->uniform_array_size = MAX2(MAX2(16, uniform + 1),
                                             c->uniform_array_size * 2);

                c->uniform_data = reralloc(c, c->uniform_data,
               to act as Fe^2+^/H^+^ exchangers. Thus it is interesting that the observed transport via sPfVIT occurred without the need to acidify the yeast vacuoles by the addition of ATP, which activates endogenous V-type H^+^ pumps. To support this finding, we further demonstrated that Fe^2+^ transport via sPfVIT was insensitive to the V-type H^+^ pump inhibitor bafilomycin A1 or to the proton ionophore CCCP ([Fig. 2d](#f2){ref-type="fig"}). Furthermore, to address the possibility that the transport measurements via sPfVIT are an artefact of Fe^2+^ vesicle surface binding, several additional experiments were performed ([Supplementary Fig. 3b](#S1){ref-type="supplementary-material"}). Adding the divalent cation chelator EDTA to the wash solution used during transport experiments (see Methods section) had no effect on ^55^Fe^2+^ uptake, while lysing vacuolar vesicle preparations by either three freeze-thaw cycles before experimentation or


performed to characterize the transport properties of ZIPCO; iron and zinc supplementation and depletion experiments suggested it plays a role in uptake of iron and zinc across the plasma membrane[@b26]. Mechanisms used by the parasite to store and detoxify excess iron remain unknown. Asexual erythrocyte stage parasites face high demands for maintaining iron homeostasis as they digest iron-containing haemoglobin and the LIP increases with their maturation from ring to schizont forms[@b32]. VIT family members have been described in plants and yeast[@b8][@b11][@b12][@b13][@b33][@b34] and, more recently, in the human pathogen *Trypanosoma brucei*[@b35] as important iron regulatory mechanisms. Our study is the first to characterize VIT homologues in *Plasmodium* and the first to confirm the iron transport properties of any VIT homologue.

We show here that expression of PfVIT restores transport ofFe^2+^ transport via VITs have yet to be demonstrated. Here we have measured ^55^Fe^2+^ uptake into isolated yeast vacuoles expressing sPfVIT (confirmed by western blot). sPfVIT-mediated ^55^Fe^2+^ uptake was consistent with transport via a Fe^2+^-specific carrier protein, with an estimated *K*~m~ value of approximately 15 μM, that was relatively insensitive to pH between 6.5 and 7.5 (note the physiological range of the parasite cytosol is pH 7.1--7.3 ref. [@b37]). The *K*~m~ value would suggest that PfVIT is a relatively low affinity/high capacity transport pathway, given that LIP measurements in malaria parasite iRBCs are 0.2--2 μM (ref. [@b38]). Most VITs have been proposed to be Fe^2+^/H^+^ exchangers, given their localization and proposed role (see below), with Fe^2+^ being accumulated into acidic vacuoles. Yet our data were produced without the need to


4*s. Calculate m(h).
5
Let g(h) = -6*h + 137. Let p(a) = 3138*a - 18814. Let y be p(6). Calculate g(y).
53
Let n(g) = -g**3 + g**2 - g + 3. Let x be ((-10)/6)/((-15)/45). Suppose -x*y + 15 = 3*j, 0 = -6*y + 2*y + j + 12. Calculate n(y).
-18
Let q(v) = v**2 - 13*v + 17. Suppose -4*h - 17 = -3*b, 76 - 58 = 2*b + 4*h. What is q(b)?
-25
Let v(n) be the second derivative of -n**4/12 + 2*n**3/3 + 7*n**2 - n - 925. Determine v(6).
2
Let w = 5516 + -5514. Let s(t) = t**2 + 4*t. Let z(x) = 6*x + 0 + 3*x**2 + 1 + x. Let p(n) = w*z(n) - 5*s(n). Calculate p(5).
-3
Suppose 3*x + 0*x + 31 = -2*d,6*i + 2. Let z(n) = -9*n**3 + 4*n**2 - 48*n - 9. Calculate 4*a(w) + z(w).
-9*w**3 - 24*w - 1
Let q(p) = 3*p. Let x be (28/((-24)/(-6)))/(1/(-43)). Let t = -298 - x. Let k(a) = -a**2 + 4*a. Give t*k(b) - 4*q(b).
-3*b**2
Let a(w) = -7*w + 4. Suppose -3*s + 0*c + 2*c = -28, 2*s = -4*c - 8. Let b(h) = -s + 10*h + 4 + 0 - 4. Suppose 0*n + n = -446 + 439. Determine n*a(k) - 5*b(k).
-k + 2
Let b(n) = -31713*n**2 - 63*n + 21. Let j(a) = 3171*a**2 + 6*a - 2. What is 2*b(u) + 21*j(u)?
3165*u**2
Let d(c) = -3*c**3 + 2*c**2 - 1. Let a(p) = -8*p**3 + 299*p - 4. Give -a(b) + d(b).
5*b**3 +


be short and thus aligns equally well to a large number of genomic positions. Guessing the true origin can be further hampered by polymorphisms near the splice site. Besides *incorrect* spliced alignments, this can also lead to *missed* splice junctions, i.e., exon--exon junctions that are not supported (covered) by any spliced alignment. Missed junctions can also result from read coverage fluctuations (biases) or a generally low transcript abundance. While some of the existing methods do take into account incorrect alignments by applying ad hoc filters (Scripture \[[@CR9]\] and CLIIQ \[[@CR10]\]) or by not requiring the isoform selection model to explain all input alignments (MITIE \[[@CR11]\]), none of the existing approaches is able to deal with missed junctions. In this work we present a novel framework CIDANE (comprehensive isoformsimultaneously and balance minimality and accuracy heuristically.Among methods that simultaneously optimize for both objectives, the measure of minimality has an enormous impact on the tractability of the resulting problem. The most immediate measure, the number of predicted transcripts (*L*^0^ norm), leads to non-convex objectives and a computationally intractable optimization problem. Methods like MITIE, StringTie, Montebello \[[@CR19]\], and iReckon, which employs a novel non-convex minimality measure, therefore resort to a forward stepwise regression strategy, a Monte Carlo simulation, or numerical optimization combined with random restarts, that generally do not find the best solution in this model. Methods like SLIDE and IsoLasso thus replace the *L*^0^ norm by the convex *L*^1^ norm, i.e., the sum of transcript abundances.Concerning the measure of accuracy, methods apply a least-squares loss function (e.g., IsoLasso,


modeled by a normal distribution *N*(250,25) for the 75-bp reads and *N*(300,30) for the 100-bp reads. We mapped each set of paired-end reads to the set of known transcripts using TopHat2 \[[@CR25]\]. We defined the ground truth as the set of all annotated transcripts (UCSC) for which at least one paired-end read has been produced.

We compared the performance of CIDANE to the transcriptome reconstruction quality of StringTie \[[@CR18]\], Cufflinks \[[@CR2]\], CLASS \[[@CR13]\], IsoLasso \[[@CR17]\], SLIDE \[[@CR16]\], and MITIE \[[@CR11]\]. All recall and precision values achieved by CIDANE include transcripts with uncovered splice junctions predicted in phase II. We did not include iReckon and GRIT \[[@CR26]\] in this first benchmark as both methods require TSSs and TESs to be provided, which, as shown by the experiments in Sections "[Annotation-guidedCAGE, and PAS-seq](#Sec14){ref-type="sec"}" show that the superior performance of CIDANE compared to StringTie and Cufflinks cannot be attributed (only) to the additional exon boundary information. When provided with the exact same partial annotation of transcripts (Section "[Transcript assembly with partial annotation](#Sec6){ref-type="sec"}") or when exon boundaries are inferred from the read data alone (Sections "[Integrating real RNA-seq, CAGE, and PAS-seq](#Sec14){ref-type="sec"}" and "[Ab initio prediction](#Sec11){ref-type="sec"}"), CIDANE still outperforms all existing methods.

The relative performance of the tools is similar on the larger data sets (Additional file [1](#MOESM1){ref-type="media"}: Figure S3). Cufflinks, however, seems to have difficulties assembling the 80 million 100-bp read pairs. Recall and precision achieved by the tools for the four different experimental designs are listed in Additional file [1](#MOESM1){ref-type="media"}: Tables S1, S2, S3, and S4.

#### Dependence on transcript abundance


specifically for the statistical estimation of abundances on the set of transcripts assembled by CIDANE, we expect a further improvement in accuracy. A known (or reconstructed) set of expressed transcripts allows for more involved statistical models that often operate, like iReckon's expectation-maximization algorithm, at single-read resolution. Fig. 4Fraction of correctly predicted expression of known isoforms (*Annot*) at different error thresholds

### Delayed recovery of transcripts {#Sec8}

In this benchmark, we demonstrate the capability of CIDANE to recover in phase II (see Fig. [1](#Fig1){ref-type="fig"}) isoforms containing splice junctions that are not supported by any read. Note that a junction between neighboring exons can also be supported ("covered") by a read pair that maps to the two exons, even if none of the reads span the junction. From the ∼ 6300 transcriptsreal RNA-seq, CAGE, and PAS-seq](#Sec14){ref-type="sec"}", information available on TSSs and TESs also significantly enhances CIDANE's assembly of transcripts. If the biological question involves a known set of genes, for example, then gene boundary information prevents fragmentation and fusion of genes caused by missing and ambiguous read alignments, respectively, and thus, helps to improve significantly both the sensitivity and precision of CIDANE's prediction. Not surprisingly, combining exon boundary, splice junction, gene boundary, or TSS and TES information yields even more accurate transcript reconstructions. At the extreme end of the spectrum, allowing CIDANE to exploit the full information content of the annotated transcriptome yields assemblies of the blood and monocyte reads that contain 10,883 (25,769 vs 14,886) and 14,724 (25,970 vs 14,246) more correctly discovered transcripts than CIDANE's ab initio


 \begin{document}$\mathcal {T}$\end{document}$ contain all transcripts that were correctly assembled by one of the four most accurate methods based on the full set of 180 million (blood) and 240 million (monocyte) read alignments, respectively. The numbers shown are conservative estimates of the true numbers of invisible transcripts. They do not include transcripts invisible in the full set of alignments and most methods filter the lowest-expressed transcripts for each gene, which would become invisible even if large fractions are sampled. Furthermore, invisible transcripts among false negative predictions are not taken into account either. Nevertheless, even in real RNA-seq data sets containing 54 million (blood) and 72 million (monocyte) reads, between 656 and 949 transcripts that were correctly assembled by StringTie or CIDANE from the full set of reads are \usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
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                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$c_{i}=(\bar {s}_{i},\bar {s}'_{i},b_{i})$\end{document}$ then counts the number *b*~*i*~ of read pairs *r*=(*r*~1~,*r*~2~) where *r*~1~ and *r*~2~ map with a *signature* consistent with $\documentclass[12pt]{minimal}


          \usepackage{amssymb}
                \usepackage{amsbsy}
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                \begin{document}$\mathcal {PAS}$\end{document}$, which contain potential TSSs and TESs, respectively. These sets can be compiled from annotated TSSs and polyadenylation sites, additional read data from the $\documentclass[12pt]{minimal}
           graph that start at a segment in $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
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                \usepackage{upgreek}


and the cDNA fragment length distribution. Equations defining *ℓ*~*t*,*c*~ as used in our model are given in Additional file [2](#MOESM2){ref-type="media"}: Section 3. In contrast, methods like TRAPH \[[@CR12]\], MITIE, and IsoInfer/IsoLasso define coefficients *ℓ*~*c*~ that neglect the dependence on transcripts *t*. Note that the distribution of reads along a transcript is generally not uniform, but typically unknown. The same applies to all the experimental data used in this study. Any prior knowledge concerning the likelihood of starting positions can be incorporated into our model through adjusted *ℓ*~*t*,*c*~ coefficients.

We employ the sum of squared errors (i.e., differences between estimated and observed number of reads) as a measure of accuracy of our prediction, weighted by an estimator for the variance of observations *b* \[[@CR14]\]. Fitting our model using all candidate \usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document} $$ \min_{\theta\geq 0} \sum_{\substack{c=(\bar{s},\bar{s}',b): \\ c \in \mathcal{C}}} \left(\frac{b-\sum_{t\in T}{\ell_{t,c}\theta_{t}}}{\sqrt{\max\{\epsilon,b\}}}\right)^{2} + \lambda \sum_{t \in T} \theta_{t}  $$ \end{document}$$

For faux covers, we replace *b*=0 by *ε* (default *ε*=1).


This so-called *Lasso* regression *selects* isoforms by setting the expression levels of all other transcripts to zero one at a time with increasing penalty terms *λ*.

The overall quality of the prediction crucially depends on the right choice of the regularization parameter *λ*. In contrast to previous methods, we balance the relative importance of the accuracy of the prediction and its simplicity (number of transcripts with non-zero expression level) based on the entire path of values for *λ*. As the coefficient path is piecewise linear, the entire regularization path can be computed at the cost of a single least-squares fit \[[@CR38]\]. We apply a coordinate descent algorithm implemented in the glmnet Fortran code \[[@CR39]\], that cyclically optimizes, for a given *λ*, each isoform abundance separately, holding all other abundances             \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$ \ell _{t_{j},c_{i}}$\end{document}$. The task is, therefore, to find a transcript *t*~*j*~ such that $$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}


      \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$\bar {V}(e)$\end{document}$ the set of vertices whose associated exons lie between the exons given by segments *i* and *j*, i.e., $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
               \usepackage{amsfonts}
                \usepackage{amssymb}
                \usepackage{amsbsy}
                \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$\bar {V}(e):=\{k\in V: i< k < j\}$\end{document}$. We assign to each edge *e*∈*E* a weight function $\documentclass[12pt]{minimal}


               \usepackage{mathrsfs}
                \usepackage{upgreek}
                \setlength{\oddsidemargin}{-69pt}
                \begin{document}$\hat {\ell }$\end{document}$ in the computation of *ℓ*~*t*,*c*~ (see Eq. ([1](#Equ1){ref-type=""}) in Additional file [2](#MOESM2){ref-type="media"}) that limit the lower and upper 5 *%* quantiles, respectively, of the estimated fragment length distribution. In Additional file [2](#MOESM2){ref-type="media"}: Section 7, we translate this fragment length restriction into lower and upper limits on the total length of exons in $\documentclass[12pt]{minimal}
                    \begin{document}$\mathcal {S}$\end{document}$ selected by the *x* variables form only valid exons in $\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
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                \begin{document} $$\begin{array}{*{20}l}[-2pt] x_{i} &\leq 1 - \sum_{j=i+1}^{|V|} ss_{j}, & v_{i}\in V  \end{array} $$ \end{document}$$

$$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
   to evaluation), and presence of emotional and behavioral problems. School absenteeism, use of medical resources, oral steroid dosage, other medications used to treat asthma, and pulmonary functions were not associated with academic performance. Investigation of poor classroom performance of a child with chronic asthma should include investigation of the roles of socioeconomic status, oral steroid therapy, and emotional and behavioral problems.


the media to stand together in the face of "the pressure of some groups," ISNA reported on July 9. He warned that "pressure and powerful groups" are threatening the press, which they regard as endangering their interests.

A member of the legislature's Culture Committee identified on July 9 by ISNA only as Soruri, said with some optimism that the government should "pave the way for a reduction of pressures on the media" in the run-up to parliamentary elections. The daily "Aftab-i Yazd" observed on July 9 that officials are so busy denouncing domestic enemies and previous administrations that they seemed to be overlooking topics it said were of greater concern to Iranians and Muslims. The paper said such matters include the recent reported mistreatment of Iranian pilgrims in Sauditrade union.

Iranian police were treating the case as a "criminal" investigation -- a classification that Bolhari says could allow them to later deny any government involvement.

Soon, Radio Farda's story was being broadcast into Iran -- one of the first reports by any of the world's media about the case.

Experienced Eye

The 44-year-old Bolhari has been working at Radio Farda's Prague offices for the past 18 months.

Before that, he worked for 17 years as a journalist inside Iran -- including work for the official "Iran" newspaper under reformist President Mohammad Khatami (1997-2005), and as an economic correspondent and international news editor for about a dozen reformist newspapers that all were shut down by Iran's conservative judiciary.

Bolhari says government intimidation and censorship against journalists in Iran makes it harder to report


below illustrates that complaints based on the ground of disability consistently far outrank other grounds of discrimination such as sex.

This table illustrates the total number of cases and percentage of total cases citing disability as the ground of discrimination received by the Canadian Human Rights Commission between 2002 and 2006 as seen in the annual reports. Note that disability is cited as the highest ground of complaint in each year. The disability figures are compared to the percentage of cases citing sex, the second highest ground of complaint received by the Commission, during the same time period. Rates citing disability as the ground of discrimination more than double those citing sex.

Reporting Year

Total number of signed complaints received by the CHRC

Number of cases where disability is cited as groundcertain mining operations and First Nations employers (for employment or service issues that are not exempt under s. 67 of the Act).

3. The Complaint Process

Section 40(1) of the Act permits any individual or group of individuals who believe that they have experienced discrimination to file a complaint with the Commission subject to certain exceptions. Additionally, s. 40(3) permits the Commission to initiate a complaint on its own volition where it has reasonable grounds to believe that a person is engaging in discriminatory acts or behaviour.

The Commission can refuse to deal with a complaint where it believes that another avenue of recourse exists, the complaint goes beyond the jurisdiction of the Act (i.e. the complaint is trivial, frivolous, vexatious or made in bad faith) or the complaint is based


adjudication with limited or no involvement by the Commission. In such situations, the responsibility for establishing a prima facy case of discrimination through the production of witnesses and official documentation rests almost exclusively with the complainant.

The Commission recognizes that legal precedents are important and serve as guides for the interpretation of the legislation. Thus, it has decided to focus its limited litigation resources on cases having the greatest impact, such as those involving allegations of systemic discrimination and precedent-setting cases that can clarify the law for all Canadians. To some degree, this model can be seen as a half way point between a model which grants all complainants direct access to the Tribunal as is the case in British Columbia and soon to be in Ontario, and aof the first steps taken by the Commission at the intake stage is to determine if, pursuant to ss. 41(1)(a) and (b), the matter at issue could be handled more effectively through another avenue such as a workplace grievance mechanism or another legislative mechanism. It argues that other redress procedures might offer a quicker, less litigious way of solving a problem. Similarly, it contends that certain specialized legislative bodies may be better placed to deal with particular situations.[30]

The Commission's decision to focus its resources on addressing systemic complaints with broad public impact accords with the aspirations of persons with disabilities.[31] However, the Commission's emphasis on screening out complaints to other avenues of redress does raise some alarm bells. While this approach is supported by the Act, there is


a rigorous application of this practice could well mean that significant human rights complaints involving employment discrimination, barriers to national transportation systems, and barriers to a host of tele-communication systems get rerouted to other redress venues. The Commission's screening practice therefore raises two key concerns for CCD.

The first concern stems from the fact that other redress venues may not offer persons with disabilities the same level of access and institutional expertise and support for resolving complaints of discrimination as may be available through the Commission. For example, the redirection of complaints forced CCD to take its complaints against VIA Rail to the Canadian Transportation Agency. Unlike human rights commissions, the Agency does not have the authority to carry the complaint in the name of the public interest andin the name of promoting the public interest, could actually provide less access to complainants rather than more access.

Recommendation #9: That the Commission interpret the notion of the "public interest" in a large and liberal manner to ensure that the resolution of complaints at the Tribunal level do not fall primarily on the shoulders of individual complainants.

Recommendation #10: That if the Commission continues to abandon complainants of an individual nature, it urge the federal government to establish a human rights legal support centre similar to the centre introduced by the Ontario government to assist complainants with Tribunal hearings.

The Commission's new business model stresses the importance and efficiency of carrying out the purpose of the Act through proactive prevention of discrimination by working with federally- regulated employers and service


accommodate: to render those services and facilities to which the public has access equally accessible to people with and without physical limitations."[39]

Recommendation #11: That the Commission adopt the findings of the Supreme Court of Canada in the VIA Rail decision into its discrimination prevention strategies. Specifically, it is recommended that the Commission adopt a plan of action based on the principles articulated in the VIA Rail decision to work proactively with employers and service-providers (particularly those in the transportation industry) to remove existing disability-related barriers and to prevent the creation of new barriers.

2. The International Convention on the Rights of Persons with Disabilities

In March 2007, the Canadian government decided to act as a signatory to the International Convention on the Rights of Persons with Disabilities (hereinafter referred toas the "Convention".[40] It is assumed that Canada will continue with this initiative by ratifying the Convention in the near future.

Article 33.2 of the Convention tasks national institutions, such as the Commission, with the role of "promoting, protecting and monitoring the implementation" of the Convention at the domestic level.

At the signing ceremony, the Commission speaking as the Chair of the International Coordinating Committee of National Human Rights Institutions (ICC) pledged that it and the other members of the ICC would take the steps necessary to give life to the Convention.[41]

This is an encouraging and promising announcement for persons with disabilities living in Canada. Unlike the Canadian Human Rights Act, the Convention spells out a wide range of specific rights to which persons with disabilities are entitled including the


26/5 of a century in decades?
52
How many minutes are there in 7/2 of a hour?
210
How many meters are there in 7.875328 millimeters?
0.007875328
What is twenty-seven fifths of a microgram in nanograms?
5400
How many grams are there in 59/4 of a kilogram?
14750
What is 48Mississippi Freedom Democratic Party Founded for preceding events.

Contents:

The Situation

The Dilemma

Pulling it Together

Mississippi Girds for Armageddon

Washington Does Nothing

Recruitment & Training

10 Weeks That Shake Mississippi

Direct-Action and the Civil Rights Act

Internal Tensions

[Sidebar: Organizational Stucture of Freedom Summer]

The Situation

According to the Census, 45% of Mississippi's population is Black, but in 1964 less than 5% of Blacks are registered to vote state-wide. In the rural counties where Blacks are a majority — or even a significant minority — of the population, Black registration is virtually nil. For example, in some of the counties where there are Freedom Summer projects (main project town shown in parenthesis):

Whites Blacks County (Town) Number Eligible Number Voters Percentage Number Eligible Number Voters Percentage Coahoma (Clarksdale) 5338 4030 73% 14004 1061 8% Holmes (Tchula) 4773 3530 74% 8757 8


taken against the politically well-connected officials who violate the law and flout the court rulings. Nor is there any relief in sight because LBJ has stripped out any meaningful voting rights protection from the draft Civil Rights bill being debated by Congress.

While most of the national media covers dramatic, photogenic events such as the Freedom Rides and the Birmingham marches they either ignore the issue of Black voting rights or relegate coverage to small articles on the back pages — leaving most Americans unaware of the brutal political realities of the Deep South.

The Dilemma

By November of 1963, Movement activists in Mississippi are exhausted, frustrated, and discouraged. Their efforts and strategies have built a movement — but not increased the number of Black voters. But movements move, if one(highly optimistic) plan calls for a large Summer Project budget, but by early May only $10,000 has been raised and there is not even $5 to fix the clogged toilet at COFO Headquarters in Jackson. Comedian and Movement stalwart Dick Gregory does a fund-raising tour that nets $97,000, but that is nowhere near enough, and on three occasions before summer SNCC is unable to pay its staff their munificent salary of $10 per week (equal to $75 a week in 2013).

Nonviolence. The issue of nonviolence is troublesome. Some activists hold to Gandhian "philosophic" nonviolence, but most organizers in Mississippi are "tactically" nonviolent. They adhere to nonviolence on protests because anything else is both counter-productive and suicidal, but self-defense outside of demonstrations is a different matter. Most Blacks in


Levison, and Bayard Rustin.

Few Freedom Movement activists have ever met an actual real-life Communist, but those who have generally consider them to be part of the, "You're going too fast, you're going too far" wing of the liberal establishment. So to those on the front lines of the Movement, the obsession over "Communist influence" is absurd and laughable — except when it threatens desperately needed fund raising. Which it very much does.

With rare exceptions, CORE and SNCC resist pressure to disassociate themselves from "dangerous radicals." Their attitude is that so long as leftists refrain from disrupting the Freedom Movement with extraneous political controversies, anyone willing "to put their body on the line" is welcome to participate regardless of their political beliefs or affiliations.

After John Lewis' speech at theMarch on Washington, and with growing media attention on the upcoming Summer Project, liberal pundits such as Theodore White and Arthur Schlesinger step up their attacks on SNCC, and SNCC's association with "Reds," while conservatives such as Evans & Novak allege that SNCC has been "penetrated" by "subversive elements." The FBI's COINTELPRO operation increasingly focuses on SNCC, working to isolate it and destroy its funding base. A favorite tactic is to plant smear stories in the media. One example is the The New York Times article titled, " Hoover Says Reds Exploit Negroes ," which runs shortly before the start of Freedom Summer. Hoover is enraged when Lewis responds with "The Director of the FBI should spend less time turning over logs looking for the Red Menace and


dawn-to-dusk curfews, and making it a crime to pass out leaflets advocating a boycott. The number of State Troopers is doubled, cities and towns hastily deputize and arm white men (many of them Klansmen) to repel the "beatnik horde." Jackson police purchase 200 new shotguns, stockpile tear gas, build troop carriers and searchlight trucks, and convert an armored car into an urban battle tank. Mayor Allen Thompson tells a reporter: "This is it. They are not bluffing, and we are not bluffing. We are going to be ready for them. ... They won't have a chance."

Washington Does Nothing

While white Mississippi mobilizes to defend the "Southern Way of Life" with billy clubs and jail cells, guns and bombs, the White House and Justice Department do nothing. Despite repeated pleasThere is no response.

At the volunteer-orientation in Oxford Ohio, DOJ official John Doar addresses the volunteers who are about to go down into Mississippi. They ask him: "What will be the role of the federal government in protecting our lives?" He replies that so far as their government is concerned they will have to take their chances with a hostile state — defenseless. They will be in the same situation that southern Blacks have endured for generations. The volunteers boo, but Bob Moses stops them, saying, "We don't do that." He tells them that Doar is just being honest.

This utter failure of the Johnson administration and Congress has tragic human consequences.

I remain convinced to this day that the slightest intervention — public or private — indicating firmly to


are arriving at COFO headquarters in Jackson — close to 1200 by June — and the screening process begins. The most important issue of concern is a volunteer's willingness to accept and work under the leadership of Blacks who might have little or no formal education. Where feasible, candidates are interviewed by SNCC or CORE staff, Friends of SNCC or CORE chapters, or sympathetic professors.

In truth, we ended up actively discouraging many more people than we accepted. [We needed volunteers who were] in control of their lives. Sober, intelligent, self-controlled, disciplined folk who were clear on what they were getting into and why. ... People, we hoped, who could handle a kind of stress they had never before imagined, much less encountered. ... No missionaries going to savethe benighted Negro or martyrs looking for redemption through suffering. ... No mystics. No flakes. No kids in rebellion, looking for attention or to get back at Mom and Dad. No druggies, beatniks, or premature-hippie types — too irresponsible. Plus folks in Mississippi wouldn't know what to make of them. Nobody flunking out of school and looking for a place to crash. No self-righteous ideologues or zealots out to make a personal statement to the world. — Kwame Ture. [1]

The Volunteers. Most histories estimate the number of Freedom Summer volunteers at between 700 and 1,000. This includes the 550-600 who attend one of the two training sessions at Western College for Women in Ohio and some or all of the many who arrive in Mississippi later. But those


all — violence.

Stories of violence, warnings of violence to come, training in how to survive beatings and jailings, frank discussions about fear and courage and endurance. Workshops in Nonviolent Resistance teach the techniques of survival when under attack, and the volunteers are trained in the safety practices and security procedures that are habitual with SNCC and CORE field staff:

Don't let cops or whites see you enter or leave the Black home where you are staying.

Don't carry the names of local supporters on you, don't tell cops or strangers who you are living with.

Keep the shades down at night and never stand in a lighted doorway.

Remove the dome light of your car so it doesn't illuminate you when the door is opened.

Each morning check your car for bombs (Volunteerrespected me for what I knew and what I had to offer. They wanted to know my ideas, to get my advice about what they should do. I was telling them what to do. Even in my own community, as a woman, my opinion didn't mean much unless it was in agreement with a man's. I had been beat way down, and the realization that I had something of value to give someone else was a powerful sensation. At the time I didn't even know how to describe it, but it gave me strength. — Unita Blackwell. [7] [ Unita Blackwell went on to become a SNCC field secretary and MFDP Delegate. In later life she became the first Black women in living memory to be elected Mayor


support those trying to register, and call attention to the denial of basic human rights in Mississippi, Black students eager for direct action are asked to peacefully picket the courthouse in violation of the state's anti-picketing law — it is certain they will be arrested. Most of the summer volunteers also want to join the line, but if everyone is in jail the main work of the project halts, so only a limited number are chosen.

On July 16, the line of Black adults waiting to register stretches down the courthouse steps and around the corner. No more than three are allowed into the courthouse at a time. The line crawls forward at a snail's pace — most will never even reach the door. A swarm of local andbut the families hold firm and prevail. The first autopsy done under FBI and state authority had reported no injuries other than the fatal gunshots, but Dr. Spain discovers obvious evidence of horrendous torture and brutality suffered by James Chaney. He tells reporters:

I could barely believe the destruction to these frail young bones. In my 25 years as a pathologist and medical examiner, I have never seen bones so severely shattered, except in tremendously high speed accidents or airplane crashes. It was obvious to any first-year medical student that this boy had been beaten to a pulp. — David Spain. [15]

Mickey Schwerner's parents ask that his body be buried next to James Chaney, but that violates Mississippi's rigid code of segregation extending even unto death — whites and


Associated Press

TRENTON, N.J. (AP) — A bill inspired by former "Jersey Shore" star Nicole "Snooki" Polizzi to cap what state public universities can pay to speakers was approved by lawmakers Thursday and now heads to the governor's desk.

The Democrat-controlled Assembly unanimously passed the legislation to cap the spending of state money at $10,000. The legislation is now up for consideration by Republican Gov. Chris Christie, who has disparaged the MTV reality show as bad for the state's image.

Republican Assemblyman John DiMaio said he was inspired to write the measure after Snooki was paid $32,000 collected from student fees to speak at a student event at Rutgers University in 2011. Snooki's pay was $2,000 more than Nobel Prize-winning author Toni Morrison received to speak at commencement.

Christie said at ankitchen area:

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Dave and Krista are a couple from the Pacific Northwest that led overwhelmingly busy lives. As her son Hayden was graduating high school, and daughter Korynn wrapping up college, they realized it was time to slow down. Life was going far too fast . They wanted to take the time to enjoy stress free living with their eight year old son Quinn.Having visited Hush Valley Lodge as guests in January of 2016, they decided this would be the exact change they needed.In the pursuit of happiness, they partnered with Jo, Peter, Molly, Gary and Dan to make this dream a reality, and are currently the stewards of the magic that is Hush


regulatory filing, to what I estimate totaled about $155 million. And that followed a 13% slide in print ads in 2010. Meanwhile, digital ad revenue last year rose in the low single-digit percentages, nowhere near enough to make up for the print losses.

USAT has no 'enemies'
Beusse has led Sports Media since he was hired in January 2011 to consolidate all of Gannett's sports content. Whatever ethical boundaries get tested, he says he'll move carefully, reflecting the longstanding culture at USAT itself.

“If you look at Gannett’s USA Today over the years, it has never, ever really upset anyone,’’ he told Janoff. “USA Today doesn’t have any enemies. It’s a friendly publication.”

22 comments:

QUOTE Beusse must do it while finessing ethical issues posed by recent sponsorship deals he negotiated with NASCARmany ads, exactly are next to that? (see the comment just above)- at the end of the day, what revenue is coming in? Whether it's a sports sales guy or just an old print ad sales guy, it's still a conversation about selling an ad in a paper....with declining circulation and readership. All the buzz and acquisitions are about increasing audience size, but where's the revenue? Haven't seen a $$ result of all that yet...that will be the litmus test for Beusse. How long a grace period will Gracia give these guys? - a friendly publication.....yes, it's really a backhanded compliment. USAT's a respected player of coverage in the sports world as a national newspaper mainly cause of that fact alone (national) - not really considered as a


demographic data, risk factors, clinical and comorbidity characteristics for all patients are shown on [Table 1](#T1){ref-type="table"}. The echocardiographic data and characteristics for all patients are shown on [Table 2](#T2){ref-type="table"}. The pattern of atrial fibrillation is shown on [Table 3](#T3){ref-type="table"}. The pharmacological therapy and antiarrhythmic drugs are shown on [Table 4](#T4){ref-type="table"}.

######

Baseline demographics and clinical characteristics

![](MSM-29-231-g001)

######

Echocardiographic parameters

![](MSM-29-231-g002)

######

Patterns of atrial fibrillation n (%)

![](MSM-29-231-g003)

######

Pharmacological therapy n (%)

![](MSM-29-231-g004)

In our study among 2352 patients, AF was reported to be first detected in 352, paroxysmal in 194, persistent in 728, and permanent in 1078 patients. Concomitant diseases were present in 84% of all patients. As many as 79% of patients were symptomatic during the follow up period. Oral anticoagulation drugs (VKAs and NOACs) were prescribed to 44.2% of the patients withvisual medium, its relationship to the society from which it emerges, the industry which created it and those who consumed it. Despite these obstacles, film is a crucial means for understanding the recent past.1

This is the second in a (very) occasional series highlighting some of the online resources available at the Library that will be of interest to students and staff in History, Classics and Archaeology.

Archives Unbound from Gale Cengage provides access to topically-focused digital collections of historical documents. This is a vast array of valuable primary source material covering a broad range of topics from the Middle Ages onwards and the material supports the research and study needs of students and scholars. Most of collections are chosen for Archives Unbound based on requests from scholars, archivists, and


students.

At present the Library has access to 9 collections from Archives Unbound, primarily covering topics and events from the twentieth century with one exception. Descriptions of these collections comes from the Archives Unbound site. Continue reading →

This is the first in an occasional series highlighting some of the online resources available at the Library that will be of interest to students and staff in History, Classics and Archaeology.

The Digital National Security Archive (DNSA) from ProQuest gives you access to a vast collection of important declassified U.S. government documents. This provides valuable primary source material central to U.S. foreign and military policy since 1945 and helps advance research in history, politics and international relations.

Within DNSA are collections that cover U.S. policy towards critical world events, including their military, intelligence,responsibility for the persona of each individual. Although the business world is dog eat dog and that is reflected in their behaviour. Some of the tasks have had me glued, the art gallery in particular was a fascinating watch and I had the fired candidate pegged from the start. Other weeks it’s not been so easy to guess. This series has renewed my love of the show, though and I can’t wait for the next instalment.

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Rossini’s La Cenerentola makes for a refreshingly vibrant, light and comedic Opera. Welsh National Opera’s latest production is a festive treat indeed just ahead of December too, perfect timing!

It’s essentially a Cinderella story as it revolves around a kitchen maid by the name of Angelina (Tara Erraught) who is bereft of


tale of the author’s childhood festivities which were humble yet always magical with thanks to her special mother whom the book is written about.

The story works on many levels as it’s a wonderful Christmas story for youngsters and teaches the more savvy children the lesson of less being more. It also doesn’t hurt for us adults to be reminded that not everybody’s Christmas might be as privileged as our childhood Christmases were. However, although it becomes clear that the family rely upon donations in order for Santa to do his job, it’s not a subject that’s dwelt upon with melancholy undertones. It’s simply a stitch in the tapestry of the author’s memories.

I think the idea of mum being a Christmas Elf is a fantastic idea and the bookRadio Australia. The ABC's headquarters is in Ultimo, an inner-city suburb of Sydney, New South Wales.

Origin
Founded in 1929 as the Australian Broadcasting Company, the ABC was a Government licensed consortium of private entertainment and content providers, authorised under supervision to broadcast on the airwaves using a two-tiered system. The "A" system derived its funds primarily from the licence fees levied on the purchasers of the radio receivers, with an emphasis on building the radio wave infrastructure into regional and remote areas, whilst the "B" system relied on privateers and their capacity to establish viable enterprises using the new technology. Following the general downward economic trends of the era, as entrepreneurial ventures in National infrastructure struggled with viability, the "Company" was subsequently acquired to become a fully state-owned corporation


had moved into satellite broadcasting, greatly enhancing its ability to distribute content nationally. In the same year, the ABC introduced a 24-hour-a-day AM rock station in Sydney, 2JJ (Double Jay), which was eventually expanded into the national Triple J FM network. A year later, a national classical music network was established on the FM band, broadcasting from Adelaide. It was initially known as ABC-FM (now called ABC Classic FM) – referring both to its 'fine music' programming and radio frequency.

ABC budget cuts began in 1976 and continued until 1985. In 1978 the ABC NSW Staff Association organised a strike against budget cuts and political interference. Sydney ABC was off air for four days. A packed free concert in support was held at the Regent Theatre and compered bywhen he broke an election-eve promise not to make cuts to the ABC as part of his "Budget repair" program. In early 2015, an internal ABC review of its coverage of Joe Hockey's first Budget criticised the post-budget interviews by 7:30 and Lateline, finding that the interviewers had given the impression of bias.

 Support for leadership coup against Abbott

When Abbott lost the leadership to the less conservative Turnbull in the September 2015 Liberal leadership spill, the hosts of the ABC's political programs spoke in favour of Abbott's demise. Kerry O'Brien and Barrie Cassidy, hosts respectively of the ABC's flagship weekly current affairs programs Four Corners and Insiders, welcomed the replacement of Abbott by Turnbull, as did ABC radio commentators Fran Kelly Paul Bongiorno and Amanda Vanstone. Fairfax and