      sendHorizontalToo = event.ControlDown();
            break;

        case WXK_END:
            newEvent.SetEventType(wxEVT_SCROLLWIN_BOTTOM);

            sendHorizontalToo = event.ControlDown();
            break;

        case WXK_LEFT:
            newEvent.SetOrientation(wxHORIZONTAL);
            // fall through

        case WXK_UP:
            newEvent.SetEventType(wxEVT_SCROLLWIN_LINEUP);
     else
            m_targetWindow->Refresh(true, GetScrollRect());
    }

    if (oldYScroll != m_yScrollPosition)
    {
        if (m_yScrollingEnabled)
            m_targetWindow->ScrollWindow( 0, m_yScrollPixelsPerLine * (oldYScroll-m_yScrollPosition),
                                          GetScrollRect() );
        else
            m_targetWindow->Refresh(true, GetScrollRect());
    }
}

void wxScrollHelper::DoScroll( int x_pos, int y_pos


the weights, since it represents the actual ratio between the amount of values of one class vs the other. However this seems to be favoring the minoritary class, which can be seen by inspecting the confusion matrix:
array([[18881, 19195],
       [  657,  2574]])

So just by trying out different weight values, I've realized that with a fairly close weight ratio, specifically array([1, 7]), the results seem much more reasonable:
array([[23020, 15056],
       [  837,  2394]])

So my question is:

Why using the actual weights of each class yielding poor metrics?
Which is the right way to set the weights for an unbalanced problem?

A:

Depending on your choice of accuracy metric, you'll find that different balancing ratios give the optimum value ofset the device to minus two units. For lunch and dinner, he has to use a 20-unit cartridge, setting the device to minus five units at noon and to minus eight units in the evening. This all requires great care and may easily lead to mistakes.
A so-called rumen injector is also known from German Patent 3 527 066. In this device, the piston rod of the injection piston has a handle on its free end, and an adjustable stop provided on the device facing the handle limits the motion of the handle and thereby determines the injection dose. With this device, the veterinarian inserts the hypodermic needle manually into the animal, and the insertion initiates an automatic injection process, in which a spring presses the piston rod so


of defendant’s
guilty plea that defendant would be required to waive his right to
appeal, thereby making clear to defendant “ ‘that the right to appeal
[was] separate and distinct from those rights automatically forfeited
upon a plea of guilty’ ” (People v Dames, 122 AD3d 1336, 1336, lv
denied 25 NY3d 1162; see People v Barber, 117 AD3d 1430, 1430, lv
denied 24 NY3d 1081; People v Ware, 115 AD3d 1235, 1235). We further
conclude that the record as a whole establishes that defendant
understood that the waiver of the right to appeal meant that entry of
the judgments of conviction upon his plea of guilty would constitute
                            in 100% ethanol, followed by 1:1 ethanol/xylene, and 100% xylene. The antennae were spread on a slide and mounted in Canadian gum. Ten antennae were used for both males and females.

Scanning electron microscope (SEM) observation {#sec005}
----------------------------------------------

Ten insects for each gender were used for SEM observations. Antennae were dissected from the head and fixed in 70% ethanol for 2 hrs, then cleaned in ultrasonic bath (KQ118, Kunshan, China) for 1 min in the same solution, and then dehydrated in a series of graded solution of ethanol, from 70% to 100%. After treatment with 100% ethanol for 30 min, the samples were critical-point dried with a critical point dryer (LEICA CPD 030, Wetzlar, Germany). The dried antennae were mounted on holder and gold-sputtered in a Hitachi sputtering ion exchanger (HITACHI


are tightly embedded by the dendrite sheath. cw: cuticle wall, d: dendrite, ds: dendrite sheath.](pone.0174643.g007){#pone.0174643.g007}

![The morphology and ultrastructure of the type III s. coeloconica of male diving beetle *C*. *japonicus* Sharp.\
(A) SEM of the type III s. coeloconica showing this type of sensillum is characterized externally by a smooth peg, with about 10μm in height. (B) Four dendrites are located in two separated cavities, and three of them reach the tip of the peg, which was shown at higher magnification in (C), while one of them ends in a tubular body beneath the base of the peg (D), shown at higher magnification in (E). d: dendrite, tb: tubular body, ds: dendritic sheath.](pone.0174643.g008){#pone.0174643.g008}

S. placodea and the type I s. coeloconica are detected along all flagellar segments, except that theGynecology

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  { name: 'Address', type: 'string' },
            { name: 'Title', type: 'string' },
            { name: 'HireDate', type: 'date' },
            { name: 'BirthDate', type: 'date' }
        ],
        hierarchy:
        {
            keyDataField: { name: 'EmployeeID' },
            parentDataField: { name: 'ReportsTo' }
        },
     Franz Steiner Verlag Stuttgart, Stuttgart, 2006, MR2310176 (2008b:11105).
The review, written by Wolfgang Schwarz, begins, "This paper is an up-to-date (2004) and most interesting survey paper (with an emphasis on results established during the last few years) on estimates of the number of lattice points in large regions, with nearly 200 references.
"Section 1 deals with the Gauss' circle problem (Hardy's identity, O-estimates, lower bounds, mean-square estimates)."
Some other recent papers that might be of interest:
Martine Babillot, Points entiers et groupes discrets: de l'analyse aux systemes dynamiques, Panor. Syntheses, 13, Rigidite, groupe fondamental et dynamique, 1–119, Soc. Math. France, Paris, 2002. MR1993148 (2004i:37057)
Fernando Chamizo, Antonio Cordoba, Lattice points, Margarita mathematica, 59–76, Univ. La Rioja, Logroño, 2001. MR1882616 (2003j:11118)
M. N. Huxley, Integer points in plane regions and


“edition contains corrections of dates and place-names and also a few other minor corrections” ought to keep the cat from getting out of the bag.

Revelation, Translation, and Seer Stones

were seer stones (by quoting Alma 37:23-24), and uses them as a bridge to discuss the other seer stones Joseph Smith used. “He also sometimes applied the term [Urim and Thummim] to other stones he possessed, called seer stones because they aided him in receiving revelations as a seer. The Prophet received some early revelations through the use of these seer stones.” Dirkmaat also talks about Joseph Smith’s use of seer stones, yet another one of the critics favorite “hidden topics.” Dirkmaat explains, “Some of the Prophet Joseph’s earliest revelations came through the same means by which he translated thewhose type parameter happens to be called IFoo.
Maybe you were aware of this, and you really were asking, "Why would I want to constrain a generic type parameter at all?" If that's the case then I think the other answers have addressed this to some extent. But it sounded like you were asking, "Why would I define my type like that, instead of like this (since they are practically the same)?" The answer to this is, quite simply: they are not the same.

Now, here's another question—one you didn't ask, but the one I originally set out to answer ;)
Why define a type like this:
class A<T> where T : IFoo
{
    T GetFoo();
}

...instead of this?
class A
{
    IFoo GetFoo();
}

Here's one reason that springs to my


tumor necrosis factor α (TNF-α) but increases IL-10 expression in the LTs of the CLP group

To examine the involvement of inflammatory factors at the gene expression level in the LTs obtained from mice, the expression levels of IL-6, IL-1β, MCP-1, IL-10 and TNF-α were quantified using RT-qPCR ([Fig. 5](#f5-etm-0-0-7779){ref-type="fig"}). IL-6, IL-1β, MCP-1 and TNF-α expression were upregulated in the CLP group; however, this upregulation was attenuated in the TQ + CLP group. By contrast, IL-10 expression was downregulated in the CLP group; however, this was upregulated in the TQ + CLP group.

Discussion
==========

To the best of our knowledge, TQ affects autophagy in myocardial ischemia-reperfusion (I/R) injury in Langendorff- perfused rat hearts and exhibits anti-inflammatory activities in rheumatoid arthritis rat model ([@b25-etm-0-0-7779],[@b26-etm-0-0-7779]). However, limited information is available regarding the effectin the prevention and cure of various diseases. A previous study reported that TQ dose-dependently increased intracellular LC3 expression in camptothecin-11-resistant LoVo colon cancer cells ([@b37-etm-0-0-7779]). Additionally, Chu *et al* ([@b38-etm-0-0-7779]) reported that TQ treatment increased the accumulation of autophagosomes in human squamous carcinoma cells. As for beclin 1, the present study indicated that pretreatment with TQ may increase expression of beclin 1 in CLP-induced sepsis. Wan *et al* ([@b36-etm-0-0-7779]) demonstrated that the expression of autophagy-associated proteins, including beclin 1, declined to basal levels by 12 h post-CLP. Liu *et al* ([@b39-etm-0-0-7779]) revealed that TQ increased beclin 1 gene and protein expression levels; this result was in accordance with the results of the present study. However, high p62 aggregation in the LT was observed in the CLP group


Q:

Find an equation of the plane spanned by $v_1$ and $v_2$, find a vector $v_3$ that can be added to produce a basis for $\mathbb{R}^3$

Let $v_1=(-1,2,3)$ and $v_2=(5,3,-1)$. Find the equation of the plane spanned by $v_1$ and $v_2$. Also find a vector $v_3$ that can be added to the set $\{v_1,v_2\}$ to produce a basis for $\mathbb{R}^3$.
I'm stuck on both parts because everywhere I read it says I need a point in addition to these two vectors to find the equation.
For the second part I'm not sure of the method to find a vector to produce a basis, we haven't been told how to do that... I know a basis for $\mathbb{R}^3$ would have to have $3$ vectors that span $\mathbb{R}^3$ and must be L.I., sowith a SMART Board interactive whiteboard needs to know how to make use of the interactive features of a SMART Board. And in order to become comfortable in using these tools this site http://www.fuuni.com/smart/smart provides for teachers an easily accessible series of bite-sized videos on specific tasks. So when you need to know how to do a specific task you can quickly find the appropriate video and watch just that video. Each video is only a few minutes in length so is straightforward to get going with just what is needed. Beside the title of each video the length of the video is indicated.

When that skill is embedded there are ideas for moving on to make greater use of the interactive features of the SMART Board. It’s when


that a cyberattack occurred in 2014—because it didn’t, as Wheeler reaffirmed this June—Pai’s FCC dreamt up its own version of events last year. Suddenly the fake attack was canon; it was shared with the Wall Street Journal, which happily reported it; and a new reason was concocted to explain away why the baseless 2014 “attack” had never been reported via official channels before: Wheeler had wanted it kept secret.

Mainly, the bogus claim that the agency had been attacked three years ago was used to bolster the much newer claim that it had been attacked “again” last year. As Gizmodo reported out the trail of inconsistencies and dubious leaks, the interests of both House and Senate lawmakers was piqued. And while answers were demanded, every effort to get atthe truth has been stymied by Pai and the officials under him.

The agency has effectively instituted a media blackout over the controversy by refusing to respond to questions about it from reporters at multiple outlets. Repeated inquiries from Gizmodo, dating back to June 1, have received no response. The FCC did not respond to request for comment for this story either

The FCC’s claims are currently under investigation by its own inspector general, as well as the General Accountability Office, Congress’ watchdog.

Dingell was able to press Pai in person this week, however, during a televised oversight hearing. But in response to having a long list of times Dingell and others had requested information from him read aloud, Pai declined to answer any questions, saying he is legally forbidden from


&sensor_dev_attr_temp1_input.dev_attr);
	device_remove_file(dev, &sensor_dev_attr_temp1_max.dev_attr);
	return err;
}

static int w83l785ts_remove(struct i2c_client *client)
{
	struct w83l785ts_data *data = i2c_get_clientdata(client);

	hwmon_device_unregister(data->hwmon_dev);
	device_remove_file(&client->dev,
			   &sensor_dev_attr_temp1_input.dev_attr);
	device_remove_file(&client->dev,
			   &sensor_dev_attr_temp1_max.dev_attr);

	return 0;
}

static u8 w83l785ts_read_value(struct i2c_client *client, u8 reg, u8 defval)
{
	int value, i;
	struct device *dev;
	const char *prefix;

	/*
	 * We might be called during detection, at which point the client
	 * isn't yet fully initialized, so we can't use dev_dbg on it
	 */
	if (i2c_get_clientdata(client)) {
		dev = &client->dev;
		prefix = "";
	} else {
		dev = &client->adapter->dev;
		prefix = "w83l785ts: ";
	}

	/*
	 * Frequent read errors have been reported on Asus boards, so we
	 * retry on read errors. If it still fails (unlikely), return the
	 * default value requested by the caller.
	 */
	for (i = 1; i <= MAX_RETRIES; i++) {
		value = i2c_smbus_read_byte_data(client, reg);
		if (value >= 0) {
			dev_dbg(dev, "%sRead 0x%02x from register 0x%02x.\n",
				prefix, value, reg);
			return value;
		}
		dev_dbg(dev, "%sRead failed, willthe “Saudi Arabia” of tidal power.

Observers have long speculated about the potential for electricity generation using tidal energy, and though there are still only a handful of tidal power plants completed worldwide, many other projects are nearing construction or have been proposed. Of these, none equals the Pentland Firth in terms of estimated power generation capacity—Scotland has suggested it could provide as much as 10 gigawatts of electricity on average over the course of a day, enough to supply a quarter of the European Union’s daily needs—and as a result, a number of energy companies have recently acquired leases to install turbines in the waterway.

Until now, though, despite the lofty predictions, no scientists had conducted a systematic study to figure out exactly how much energy the Firth might


be generated.
The commercial ethane dehydrogenation process, which is an equilibrium limited thermal reaction, must rely on the use of high reaction temperatures to obtain reasonable per pass yields of ethylene. As a result of the high temperatures required, rates of competing cracking and coking reactions are high enough to adversely affect product selectivities.
Convent onal oxydehydrogenation processes, which are not inherently equilibrium limited, also suffer from poor product selectivities at high ethane conversions.
The present invention overcomes the disadvantages inherent in the prior art processes in order to achieve high conversion to unsaturated hydrocarbons combined with low rates of competing cracking and coking reactions.
Processes for the substitution of aromatic compounds are well known. Continued efforts have been made in recent years to improve such processes in order to improve thefact women
have multiple interests...All of these things drew
criticism anyone with an IQ over 80 and enough intelligence to
know that the interests of women extend beyond fashion,
cosmetics, and celebrities and that this is not novel."

Even Dave McClure, an investor in Bustle who's also known to be
outspoken, agrees Goldberg handled his launch wrong. "There are
ways that you want to go out of the door that aren't
disrespectful to your audience,"
he told Inc.

Goldberg says he has a thick-skin from his Bleacher Report days
but has admittedly struggled with the recent criticism. He calls
the blow back "incredibly painful."

Today, he's written a heartfelt apology to all of the people he's
enraged. Titled "Take Two," his
first line sums up the lengthy post. "I messed up," says
Goldberg.

He
bullet points his initial post's biggest
mistakes.

It over-simplified the editorial landscape.

It failed to


same carrier density.

In conclusion, we studied the ultrafast relaxation and recombination dynamics of photogenerated carriers in epitaxial graphene using optical-pump THz-probe spectroscopy. We measured the interband electron-hole recombination rates in graphene for the first time. Our measurements show that the recombination times in graphene depend on the carrier density.

The authors acknowledge support from the National Science Foundation, the Air Force Office of Scientific Research (Contract No. FA9550-07-1-0332, monitor Dr. Donald Silversmith), and the Cornell Material Science and Engineering Center (CCMR) program of the National Science Foundation (Cooperative Agreement No. 0520404). The authors would also like to thank Dr. Daniel Grischkowsky and Dr. Adam Bingham from Oklahoma State University for help in the design of the THz emitters used in this work.

[99]{}

R. Saito, G. Dresselhaus and M. S. Dresselhaus,Replaceable wear liners are often incorporated into cone crushers to form the crushing surfaces used to crush various materials. Cone crushers typically comprise of an assembly that rotates about a stationary shaft resulting in a gyratory motion which is harnessed to crush material as it traverses between crushing surfaces in the crushing chamber where the replaceable wear liners are located. Material to be crushed is effectively reduced into smaller dimensions as a result of being subjected to compression between the tapered crushing surfaces of the crushing chamber. The reduced material then exits from a gap between the crushing surfaces sometimes called the “closed side setting” where the minimum width of the reduced material is predetermined by manipulating the closed side setting in accordance with the desired geometry of


extremely fortunate to live in a county with a strong public library. The Spartanburg County Public Library System consists of one main branch and nine other branches spread throughout the county. One look at their events calendar will convince you that they are a vital part of our community, reaching out to all age levels. The dedicated staff responds to community needs and would gladly (I am sure) include digital literacy training for families meeting the requirements of the FCC’s digital literacy corps.

I’m sure my public library system is not an anomaly; public libraries throughout the country make it their mission to improve the lives of those in their communities. The FCC needs to use the sense of community each library’s staff has created and provide them withon Student Achievement?

We know that our programs increase student achievement, but being able to provide data that demonstrates it can be powerful. What suggestions do you have for measuring your program’s impact?

I’m starting small. Tomorrow, two English classes are coming in for brief instruction before they begin researching aspects of the Roaring Twenties. I’ll ask them to complete a Google form and use the feedback to help us as we plan library instruction for next semester.

*You’ll want to read this excellent article for more details on their accomplishment. I do not subscribe to Teacher Librarian but was able to locate the article through SC DISCUS, the databases our state library helps provide. You might be able to locate it through databases in your own school or public library.

Library


the same name. The film tracks the gradual deterioration of perfect suburban life in post-war America as a couple slowly, painfully, unravels at the seams after their teenage daughter commits an act of political terrorism at the age of 16 to protest the Vietnam War. It marks McGregor's directorial debut, and is an ambitious project, given the difficulty of previous attempts to transform Roth's novels for the silver screen. If he succeeds in doing the novel justice, however, it is going to be brilliant.Another literary adaptation, this time from Ben Fountain's brilliant debut novel exploring the public image of war. It's the latest project from director Ang Lee (Life of Pi)Just look at Eddie Redmayne in the trailer for Fantastic Beasts. Just look at him. Look at hisfreckles. Look at his big nervous eyes. He will absolutely be the most adorable thing in a film chockablock with all manner of cute CGI monsters. In this JK Rowling-scripted addition to the Harry Potter universe, Redmayne plays Newt Scamander, a very English, Eddie Redmayne-like wizard who's something of a Lobalug out of water (look it up) in New York. Colin Farrell also stars, underneath a hairdo of immaculate hipster credentials.Dwayne 'The Rock' Johnson has the kind of star presence that is fairly unusual for ex-wrestlers. Ever since he turned his (huge, meaty) hand to acting, he's used his blindingly white grin to up the wattage of even the most rote B-movie: HerculesDisney's modus operandi is now: we heard you like Star Wars


is entered, the user may provide a further input, such as selection of a “submit” button, to signify readiness to actually complete the payment transaction.
In response to receipt of the input signifying user readiness to complete the payment the browser can then be redirected to a secure payment web page hosted on the payment gateway server. In performing the redirection, the user-entered personal or payment-related information may also be transmitted to the payment web page hosted by the payment gateway.
In many cases, following the redirection, the user completes the payment by interacting with the payment gateway's web page. For example, the user may enter credit card information or bank account and routing information through the payment interface in order to complete the payment. The payment gateway server typicallyHealth board deficits have fallen by 42% over the last year - but there are still worries about Wales' largest.

Latest end-of-year projections see a combined deficit of £97.4m across Wales' seven health boards.

But while three have broken even in the last 12 months, in north Wales Betsi Cadwaladr's deficit has risen to £42m.

Complex adult care, mental health costs and hiring agency nurses to cover staff shortages at Glan Clwyd and Wrexham Maelor hospitals are factors.

Health board deficits in Wales £m Health board 2017/18 2018/19 Abertawe Bro 32.4 10 Betsi Cadwaladr 38.8 42 Cardiff and Vale 26.9 9.9 Hywel Dda 69.43 35.5 Total 167.53 97.4

Hywel Dda had the highest deficit in the previous year - £69.4m - but is now on track to meet its forecast deficit of £35.5m,


it had "worked constructively and maturely with my officials to address a number of delivery and financial issues".

Abertawe Bro Morgannwg said it was on a target with its £10m forecast overspend and was "managing a number of potential risks" to meeting this.

From this weekend, its boundaries have changed, with Cwm Taf taking over responsibility for hospitals and health services in Bridgend.

Cwm Taf has been breaking even since 2009 and a spokeswoman said: "Being in a balanced financial position helps us to address the challenges that all health boards face to meet the needs of an ageing and growing population."

Meanwhile, Aneurin Bevan and Powys health boards both broke even for a second successive year.

Analysis by Owain Clarke, BBC Wales health correspondent

Overall, this will be very welcome news to thelayer having $3\times 3\times M \times L$ parameters. The other was a separable CNN like that shown in Figure \[fig:arch\]. This also has eight layers, with each layer having $3\times 3\times 1 \times M$ parameters for the depth-wise convolution and $1\times 1\times M \times L$ parameters for the point-wise convolution. In the experiment, we divided an HSI into $20 \times 20\times \text{\{number of spectral bands\}}$ blocks and used them as inputs. The training was carried out by carefully tuning the hyper-parameters to attain the best performance. Note that this training with differs from DIP in that we used the image as is, while DIP starts with random samples to generate a clear image.

Figure \[fig:cs\] illustrates an example of the hole-filling task. Figure \[fig:cs\] (a) and (b) show the


    ![image](./images/Loukia_hip.eps){width=".18\linewidth"}
    ![image](./images/Nefeli_org.eps){width=".18\linewidth"}     ![image](./images/Nefeli_dip.eps){width=".18\linewidth"}     ![image](./images/Nefeli_n2v.eps){width=".18\linewidth"}     ![image](./images/Nefeli_hip.eps){width=".18\linewidth"}
                            Original                                                       DIP                     of our knowledge, this is the first work that shows the superiority of deep learning for HSI restoration over the conventional model-based methods.

[^1]: This work was partially supported by the Ministry of Internal Affairs and Communications of Japan under the Strategic Information and Communications R&D Promotion Programme of 2017, No. 3620.

[^2]: The authors are with the Department of Information System Engineering, The University of Kitakyushu, Japan (email: okuda-m@kitakyu-u.ac.jp).


wrote about the African American experience and issues of exclusion and belonging. She was the first black woman to become a Nobel laureate. 📸: Helen Marcus, @smithsoniannpg https://t.co/nrVW1hP6Dz pic.twitter.com/NoJsa0bZdp — Smithsonian (@smithsonian) August 6, 2019

"It has to be both: beautiful & political at the same time. I’m not interested in art that is not in the world. And it’s not just the narrative, it’s not just the story; it’s the language & the structure & what’s going on behind it."

—Toni Morrison (1931–2019) pic.twitter.com/FEncMHvTX3 — Poets.org (@POETSorg) August 6, 2019

“Art invites us to know beauty and to solicit it, summon it, from even the most tragic of circumstances. Art reminds us that we belong here. And if we serve, we last.”

Rest in power, Toni Morrison, a fearless genius whoseit is also critical to refuse to succumb to its malevolence.” - Toni Morrison#ToniMorrison pic.twitter.com/56uEwzfiDf — Greg Proops (@GregProops) August 6, 2019

Toni Morrison was the first African-American woman to win a Nobel Prize. May she rest in power. #RememberHerName https://t.co/0Q6MX8MJF7 — Billie Jean King (@BillieJeanKing) August 6, 2019

Our American story has lost a singular and courageous voice. Toni Morrison had to overcome the founding prejudices of her nation to claim a rightful place among the greats of American letters. The brilliance of her mind and spirit will live on in her words. May she rest in peace. — Dan Rather (@DanRather) August 6, 2019

Like honestly has there ever been a baddie as bad as Toni Morrison? A woman who published her first novel at 39 after waking up


need to save room for dinner. There is also a decadent box of chocolates included to take home.

Available on Wednesday, Thursday, Friday & Saturday at 2.45pm / Sunday at 3.45pm.

Breakfast is as fresh as the day at Woodman Estate. Dining inside or out overlooking the breathtaking private lake, is indeed the perfect vista to enjoy your first meal of the day. Gourmet cooked breakfast, fresh seasonal fruit and Estate squeezed juices, muffins and bircher muesli are just a sample of the many delights to enjoy. Includes a glass of Woodman Estate Sparkling for each guest.

Breakfast is as fresh as the day at Woodman Estate. Dining inside or out overlooking the breathtaking private lake, is indeed the perfect vista to enjoy your first meal of the day. Gourmet cookedChalet at the time of your choice and features continental selections, an a la carte cooked breakfast, fresh juices and espresso coffee and tea choices.

Treat someone special. Enjoy open fires in Winter and Terrace dining by the lake in Summer. Choose two courses (and a side to share) from our outstanding a la carte menu with a glass of Woodman Estate wine to savour. Finish with tea / coffee and a chocolate and then enjoy a leisurely stroll in the gardens.

Arrive and enjoy a leisurely stroll by the lake before taking your seat in the Brasserie Restaurant. Enjoy 3 courses from our sumptuous a la carte menu plus your choice of one side to share and a bottle of Woodman Estate wine. Coffee & chocolates will top off


style and which academy they join to fulfill this need. The objective is to get more people to come out of their homes and take dance as a group or shared activity," he added.

Lewis became popular as a mentor and judge on Zee TV's Dance India Dance, and he has imparted dance lessons to many people through his institute Terence Lewis Academy.

"I took up this initiative on behalf of the UNESCO's Counseil De La Danse, where I am a member representing India. This is a non-profit initiative that I have chosen for the aam janta (common man)," he said

"I would like the whole of India to take up dance not as a fun activity, but serious lifestyle change activity. If we can do regular exercise, then why can'tmost anxious to go,” Washington wrote. “In fact I made them believe that I was tereblely afred of the Yankees, any way. My Master was well satisfied at my appearant disposition and told me I was quite Right, for if the Yankees were to catch me they would send me to Cuba or cut my hands off or otherwise maltreat me. I of course pretended to beleive all they said but knew they were lieing all the while.”

Washington secretly resolved to remain in Fredericksburg until his employer prepared to leave, then conceal himself and await the arrival of the Union army. Washington’s calculations paid off when Union troops arrived in April 1862. After serving as an army guide, he eventually found freedom in Washington, D.C.

Now I’m perfectly aware


If block producers do not know the nature of a transaction, it’s harder for them to discriminate against it. This is one of the reasons privacy-preserving transactions help with censorship resistance. However, these currently only really work for simple transfers and not for complex interaction with smart-contracts.

One way to take this idea and apply it to arbitrary transactions is to allow for encrypted transactions which block producers must later decrypt for the chain to advance.

This works as follow:

A user picks uses RSA timelock encryption to encrypt a transaction and publishes the transaction.

Block producers include the encrypted transaction, which has, at this point no effect.

Block producers start cracking the timelock encryption.

During that time, the user can submit of factoring of the RSA modulus and, absent censorship, it gets included,presented in Fig. [4A](#Fig4){ref-type="fig"}. Adding a large excess of non-labeled affibody molecule resulted in a highly significant (p \< 5 × 10^−7^) reduction of cell-associated activity. This demonstrates a saturable character of binding and indicates specificity for CAIX.Figure 4(**A**) *In vitro* specificity of \[^111^In\]In-DOTA-HE~3~-ZCAIX:2 binding to renal cell carcinoma SK-RC-52 cell line. In blocking group, receptors were pre-saturated by 100-fold excess of nonlabeled HE~3~-ZCAIX:2. (**B**) Internalization of \[^111^In\]In-DOTA-HE~3~-ZCAIX:2 by renal cell carcinoma SK-RC-52 cells during continuous incubation. Cells were incubated with conjugate (10 nM) at 37 °C. Data are normalized to the highest cell-bound activity and presented as mean values from 3 cell dishes and SD. Error bars might be not seen because they are smaller than symbols.

Data concerning processing of \[^111^In\]In-DOTA-HE~3~-ZCAIX:2 by SK-RC-52 cells during continuous incubation are presented in Fig. [4B](#Fig4){ref-type="fig"}. The binding and


an imaging camera. Detection of such small metastases requires a high absolute tumour uptake and contrast with normal tissue, especially at the main metastatic sites^[@CR44]^. For RCC, metastases are most frequently observed in lungs and bone, and somewhat less frequently in liver and brain^[@CR45],[@CR46]^. Accordingly, a probe for visualization of CAIX expression in RCC metastases should have maximal tumor-to-lung, tumor-to-bone, and tumor-to-liver ratios. High tumor-to-blood ratio is always desirable to reduce the background that is due to the blood-borne activity. Thus, development of very good binders with high affinity and high tumor uptake is not enough; we have to minimize the uptake in critical tissues by reduction of off-target interactions. We took into account these considerations when planning further improvement of an affibody-based tracer for imaging of CAIX inmin before adding of \[^111^In\]In-DOTA-HE~3~-ZCAIX:2, CAIX on cells in a set of three dished was pre-saturated by non-labeled HE~3~-ZCAIX:2 to a total concentration of 1 mM. All cells were incubated for 1 h at 37 °C in a humidified incubator equilibrated with 5% CO~2~. Then, the medium was collected, the cells were washed with cold serum-free medium and detached by treatment with trypsin-EDTA solution for 10 min at 37 °C. The detached cells were collected, and the radioactivity of cells and media was measured. Binding specificity of \[^99m^Tc\]Tc(CO)~3~-HE~3~-ZCAIX:2 and \[^111^In\]In-G250(Fab')~2~ has been confirmed earlier in a similar way^[@CR32],[@CR36]^.

For evaluation of cellular processing, cells were incubated in a humidified incubator (5% CO~2~, 37 °C) with \[^111^In\]In-DOTA-HE~3~-ZCAIX:2 (at concentration of 10 nM). A set of three dishes was taken from the incubator at 1, 2, 4, 8


peak, 670 μA, 480 projections, 5.26 min acquisition time. SPECT scanning was performed during 30 min using ^111^In gamma-peaks of 245.4 keV and 171.3 keV (window width of 20%). CT raw files were reconstructed using Nucline 2.03 Software (Mediso Medical Imaging Systems, Hungary). SPECT raw data were reconstructed using Tera-Tomo™ 3D SPECT reconstruction technology.

**Publisher's note** Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This research was financially supported by grants from the Swedish Cancer Society \[grants CAN 2018/436 and 2017/425\] and Swedish Research Council \[grants 2015-02353 and 2015-02509\]. Research of Dr. Garousi is supported by a personal postdoctoral grant from Uppsala University.

J.G. participation in the study design; production of affibody molecules; labeling chemistry development; *in vitro* and *in vivo* studies, data treatment and interpretation, drafting of thephotos. Here I am right after I reached the concourse:

As you can see, I was rather excited. (It was so cold that I was wearing black gloves on both hands. I was also wearing long underwear. Just thought you should know.)

Within a minute, I was surrounded by security guards and supervisors. Fans were high-fiving me, and some of the guards recognized me and shook my hand. It was a truly awesome moment, but I knew that things could quickly turn ugly if I didn’t handle it properly. Meanwhile, the cameras had found me again. Here’s another screen shot that shows me posing with the ball:

“What’s it gonna take?” asked one of the supervisors.

“Well,” I began, “at the very least, I want to be the one to give the


Avionics

For aircraft control systems, we don't speak of operating systems but of avionics, integrated avionics or computer airborne systems in general. And they are actually a combination of a multitude of independent or inter-dependent systems, for different functions (flight control, collision avoidance, weather, communications, blackboxes...).

Each controller is usually an independent module (hardware and software) for obvious security and safety reasons: they are critical control and monitoring systems and if one of them were to fail or get damaged, it's a rather big "inconvenience" for the people which are depending on the aircraft. Dependability takes all its meaning when you are in the flying machine. So usually it's

custom built for the purpose of their mission,

built to work independently and interface with other systems,

built to be fault-tolerant to its ownCanadian Innovation Week: Celebrating Women Entrepreneurs

It’s no secret that sexism is rampant in tech culture; there’s a Wikipedia page titled “Sexism in the technology industry,” among the plethora of content that has chronicled the problem in recent years. As announced in the Federal Government’s Budget 2018, the Canadian Business Development Bank has increased the size of its Women in Tech fund to $200 million. It is now the largest VC fund in the world dedicated exclusively to investing in women-led technology companies.

Canadian Innovation Week is an opportunity for us, as a country, to celebrate innovation and mobilize around the goal of strengthening a culture of innovation in Canada. With this year’s inaugural edition of Canadian Innovation Week, it is important to look to innovation bright spots with the


that she could not defend him publicly over the matter, as demanded by the principle of cabinet solidarity.

The Canadian Press Liberal MPs Jody Wilson-Raybould and Jane Philpott take part in a cabinet shuffle at Rideau Hall in Ottawa on Jan. 14, 2019.

❤ When you add women, please do not expect the status quo. Expect us to make correct decisions, stand for what is right and exit when values are compromised. Thank you @janephilpott for articulating this beautifully. +1 https://t.co/hyVSB4MREk — MP Celina 🇨🇦 (@MPCelina) March 4, 2019

Finance Minister Bill Morneau also received some blowback online Monday for pointing out to a reporter that Philpott is a "close personal friend" of Wilson-Raybould's, remarks interpreted by some as a suggestion that her decision was driven by considerations other than herJews Demand Autonomous Jewish State Within Germany

Doubtful many Jews would ever want to return to Germany or many other places in Europe considering how badly they were treated most of the time and the German genocide of them.

That is why there are no Jews left in Poland or many other places where Hitler's Nazi's ran through. Moreover, most Jews know that far too many Europeans were only too happy to see it all happen and to take over their homes.

There are still strong anti-Semitic sentiments throughout many European countries, especially Eastern European ones.

So not likely many would want to go back there. Why give any of them even a long-shot chance to do it again?

Quoting: anonanon 4148733

Ever hear about how the Jews acted in Eastern Europe when they


time and the German genocide of them.

That is why there are no Jews left in Poland or many other places where Hitler's Nazi's ran through. Moreover, most Jews know that far too many Europeans were only too happy to see it all happen and to take over their homes.

There are still strong anti-Semitic sentiments throughout many European countries, especially Eastern European ones.

So not likely many would want to go back there. Why give any of them even a long-shot chance to do it again?

Quoting: anonanon 4148733

Ever hear about how the Jews acted in Eastern Europe when they were commies in power there?

oh the jews should not be afraid any more :-) they can come and live and work here in germany as long as they want :-)

you know:the idea to the rest of the 16 million non-German people living in Germany today, Jewish population is only 200 thousand in Germany. Maybe some kind of multikulti NGO project. The creator of the project is an artist and he says he got the idea from Ahmadinedjad in 2005 hehe, he also says he wants to test the boundaries of the the complex relationship involving Germany, Jews and Israel. Maybe it's not that organized of a plan after all but a kind of a provocative artist trying to put through a political message. He states he's non-zionist.

The important thing is that the head of the Jewish community of Thuringia (800 people according to the article) totally opposes and condemns this campaign. Being in arts meself too though Swin,


authenticated, so how will you know if to hide the 'Forgot Password' link?
In ASP.Net Identity a user can have a local login AND external account logins at same time, its built in. So if a user logged in with an external account press 'Forgot Password', the framework will create a local login for that user with a 'reseted' password (he will not reset the external login). That user will end up having to 2 ways to login in his account.
If that should be an option? In my opinion, it should.

from the UK Met Office Hadley Centre and University of East Anglia Climate Research Unit, baseline period 1850-1899 (Morice et al. 2012) with the grey area representing the 95% confidence range, 2) Red line – MLOST from the US National Oceanic and Atmospheric Administration (NOAA) National Climatic Data Centre, baseline period 1880-1899 (Smith et al., 2008), and 3) Blue line - GISSTemp from the National Aeronautics and Space Administration (NASA) Goddard Institute for Space Studies, baseline period 1880-1899 (Hansen et al., 2010). Upper graph shows annual anomalies and lower graph shows decadal average anomalies for the same datasets.

How to read the map:
Warm days are defined as being above the 90th percentile of the daily maximum temperature.
Grid boxes outlined in solid black contain at least 3 stations and so


Oceanic and Atmospheric Administration (NOAA) National Climatic Data Centre, baseline period 1880-1899 (Smith et al., 2008), and 3) Blue line - GISSTemp from the National Aeronautics and Space Administration (NASA) Goddard Institute for Space Studies, baseline period 1880-1899 (Hansen et al., 2010).

Grid boxes outlined in solid black contain at least three stations and so are likely to be more representative of the grid box. High confidence in the long-term trend is
shown by a black dot. (In the map above, this is the case for all grid boxes.) Area averaged annual time series of percentage changes and trend lines are shown
below each map for one area in northern Europe (green line, 5.6 ° to 16.9 °E and 56.2 ° to 66.2 °N) and one in south-western Europe (purple line,software predicted that there were multiple binding sites of miR-942 in the 3′ UTR region of *FOXA2* gene. As *FOXA2* is an important gene associated with tumor growth and is often low-expressed in multiple tumor specimens \[[@B15],[@B16]\], the current study further investigated the relationship between miR-942 and FOXA2 to reveal the role of miR-942 in the development of BCa cells.

Materials and methods {#sec2}
=====================

Clinical specimens {#sec2-1}
------------------

Whole blood samples were obtained from 62 participants (31 BCa patients and 31 healthy subjects) who received treatment or examination from May 2017 to January 2019 in Baoding No.1 Central Hospital (HBH20170425). Anticoagulant blood specimens were stored in a cryogenic refrigerator (3695576, Shanghai Weiwu Cryogenic Vacuum Equipment Co., Ltd., <https://b2b.hc360.com/supplyself/669456707.html>, Shanghai, China) at −20°C. The BCa tissue and adjacent tissue samples were obtained from


inserted into a pmirGLO dual-luciferase vector to generate MUT pmirGLO-FOXA2 3′ UTR. The pmirGLO vector containing WT or MT FOXA2 3′ UTR was respectively co-transfected with miR-942 mimic into MCF-7 cells, while the pmirGLO vector containing WT or MT FOXA2 3′ UTR was co-transfected with miR-942 inhibitor into MDA-MB-468 cells by Lipofectamine2000 (Invitrogen, U.S.A.). After incubation for 48 h, the relative luciferase activities in the cells were measured by Dual-Luciferase Reporter Assay protocol (Promega, Madison, WI).

Wound scratch {#sec2-6}
-------------

The transfected cells were incubated in a six-well plate at 5 × 10^5^ per well. After the cells adhered to the cell wall for 24 h, an uniform scratch was quickly drawn on the cells. After washing the suspended cells, the cells were cultured in 1% serum. Then, cell migrations atswab. Invasion cells were counted at ×200 magnification.

Cell viability detection {#sec2-8}
------------------------

The cells were seeded into 96-well plate, and 10 μl cell counting kit-8 (CCK-8) (CK04, Japanese Tongren Chemical Company, <https://china.guidechem.com/trade/pdetail8419763.html>, Japan) was added to each well and incubated for 4 h. The absorbance at 450 nm was determined by an enzyme microscopy (Multiskan GO, Shanghai Bajiu Industrial Co., Ltd., <http://www.89-china.com/>, Shanghai, China). The experiment was conducted in triplicate, and the average value was calculated.

Colony formation assay {#sec2-9}
----------------------

The cells at 100 cells/well were transfected and digested, counted and cultured in 12-well plates at 37°C for 3 weeks, and the culture medium was changed every 3 days to observe the formation of clones. The culture was terminated when the colonies filled 50--150 fields, and the medium was discarded. Next, the


CST, 14472, 1:1000), anti-glyceraldehyde-3-phosphate dehydrogenase (anti-GAPDH, mouse, 1:2000, ab8245, Abcam, U.S.A.)) at 4°C overnight. The membranes were then respectively incubated with goat anti-mouse, goat anti-rabbit and goat anti-goat IgG (H+L) HRP--conjugated secondary antibody (Proteintech, U.S.A.) for 2 h and then washed with PBS for three times. The protein bands were detected by ECL Western blotting kit (93-K820-500, MULTI SCIENCES, Hangzhou, China) and scanned by super sensitive multifunctional imager (ImageJ, version 4.7, National Institutes of Health, U.S.A.).

Quantitative real-time polymerase chain reaction {#sec2-12}
------------------------------------------------

Total RNA was extracted using TRIzol reagent (BY11909, Hefei Bomei Biotechnology Bo., Ltd., China), and Nanodrop (Thermo Scientific™, San Diego, CA, U.S.A.) was used to measure the concentration of RNA, which was then diluted to 500 ng/μl. Superscript II first-strand cDNA synthesis System (Invitrogen, U.S.A.) was used tosurvival rate of 60 BCa patients. (**C**) The expression of miR-942-3p with 1085 cancer and 104 normal samples in BRCA from database (*P*=0.001). (**D**) QRT-PCR was performed to detect the expressions of miR-942 in MCF-10A and BCa cell lines of normal breast epithelial cells (*n*=3, \*\**P*\<0.001, vs. MCF-10A). (**E,F**) The transfection of miR-942 was detected by qRT-PCR (*n*=3, \*\**P*\<0.001, vs Blank; ^\#\#^*P*\<0.001, vs MC or IC). (**G,H**) CCK-8 was used to detect cell viability (*n*=3, \*\**P*\<0.001, vs Blank; ^\#\#^*P*\<0.001, vs MC or IC). (**I--L**) Colony formation assay was performed to detect the effect of miR-942 expression on cell proliferation (*n*=3, \*\**P*\<0.001, vs Blank; ^\#\#^*P*\<0.001, vs MC or IC), U6 served as intrinsic parameters of experiment.](bsr-39-bsr20192298-g1){#F1}

The effects of miR-942 on the apoptosis and expressions of EMT-related proteins of BCa


+ siNC; ^\#\#^*P*\<0.001, vs. MC + FOXA2 or IC + si FOXA2; ^∧∧^*P*\<0.001, vs. mimic + NC or inhibitor + siNC).](bsr-39-bsr20192298-g7){#F7}

Discussion {#sec4}
==========

BCa patients are likely to develop tumor recurrence and metastasis after surgical treatment \[[@B18]\]. In recent years, miRNAs in BCa research have attracted increasing research attention \[[@B7],[@B19]\], for example studies on the interaction between miRNA with related target genes and the regulative role of signaling pathways revealed the critical effects of miRNAs on tumors \[[@B20],[@B21]\]. Thus, discovering clinical targets indicating the prognosis of BCa may contribute to the treatment of BCa.

MiR-942 has been found to regulate the development of esophageal squamous cell carcinoma, colorectal cancer and ovarian cancer \[[@B12]\]. The overexpression of miR-942 promotes the growth of esophageal squamous cell carcinoma tumors, with higher miR-942 indicating aMicrowave-assisted synthesis of phenylene-bridged aminophosphine ligands: acceleration of N-arylation and aryl fluoride phosphorylation reactions.
Hindered beta-aminoarylphosphines show promise as bidentate ligands for metal centers, but their reported synthesis requires heating at high temperatures for several days. Herein are reported conditions by which the two steps composing this synthesis, Buchwald-Hartwig amination and nucleophilic phosphorylation reactions, may both be completed in less than 3 h using microwave irradiation. The effects of several parameters on the outcome of the amination reaction are discussed, as are some indications of the scope within which each of these microwave protocols is effective.


30, 1984, ordered that "the letter and the subject matter of its contents are inadmissible and it may not be used for any purpose by plaintiff in this or any other proceeding, and that the letter and all copies and written summaries thereof shall be returned forthwith to counsel for Lawyers Title."

III
STANDARD OF REVIEW

30
A grant of summary judgment is reviewed de novo.   Darring v. Kincheloe, 783 F.2d 874, 876 (9th Cir.1986).  We will affirm only if, viewing the evidence in the light most favorable to the non-moving party (KL), there are no genuine issues of material fact and the moving party (Case Kay) is entitled to judgment as a matter of law.   See Ashton v. Cory, 780 F.2d 816, 818 (9th Cir.1986). resolving this choice of law issue:  (1) Assume that the state "which supplies the rule of decision" is the state which also supplies the privilege law;  (2) apply the privilege rules of the state in which the federal court sits;  or (3) apply the conflict of law doctrine of the state in which the federal court sits.  See 23 C. Wright & K. Graham, Jr., Federal Practice and Procedure Sec. 5435, at 865-69 (1980);  2 J. Weinstein & M. Berger, Weinstein's Evidence p 501, at 501-22 (1986).

55
We need not decide the question whether Hawaii or California law applies to the privilege issue in this case because the result is the same under the law of both states.  In both states, the client


court's action until final judgment on the merits.  KL's notice of appeal was timely filed within thirty days of final judgment on the merits.

6
 Rule 501 provides:
Except as otherwise required by the Constitution of the United States or provided by Act of Congress or in rules prescribed by the Supreme Court pursuant to statutory authority, the privilege of a witness, person, government, State, or political subdivision thereof shall be governed by the principles of the common law as they may be interpreted by the courts of the United States in the light of reason and experience.  However, in civil actions and proceedings, with respect to an element of a claim or defense as to which State law supplies the rule of decision, the privilege of ayou really don't want to miss. Included in this set is twelve of the 3" Black Composite Tactical Folders, twelve of the 4 1/2" Camo Composite Tactical Folders, featuring Stainless Steel Blade, twelve of the 5 ... (Cont'd)


and wait into one block and was thinking of using a Func.
Would this make sense in this particular case? How would such a Func loop like?

A:

Can you replace it with one if-condition?
if (wait || worker.IsPaused)
{
    Thread.Sleep(delay);
    wait = false;
    continue;
}

If wait is true you always set it to false. If it's false you will set it to false again.

Hubble time [@brown_ELM5].

All of the previously published ELM Survey analyses have noted the presence of the [Ca [ii]{} $\lambda$3934]{} K resonance line in the spectra of all ELM WDs with [$\log g$]{} $\leqslant$ 6.0. The fact that all of the lowest mass ELM WDs share this spectroscopic signature suggests that a physical phenomenon related to their evolution might be responsible. However, a systematic study of the metal abundances in ELM WDs has never been performed; abundances have only been measured for a handful of systems. These include the hot ELM WD [GALEX J1717+6757]{} [@vennes11; @hermes14b], the WD companion to [PSR J1816+4510]{} [@kaplan13], and, most recently, @gianninas14 analyzed the unusually metal-rich and tidally distorted ELM WD binary J0745+1949 (hereafter, J0745).

For canonical mass WDs, @zuckerman03 [@zuckerman10] showed that $\approx$ 25% of hydrogen atmosphere DA WDs and $\approx$ 30% of


total of 57 targets were observed at the 6.5m MMT telescope with the Blue Channel spectrograph [@schmidt89]. With only one exception, the observations were obtained using the 832 line mm$^{-1}$ grating but with two different slit widths. First, 35 targets were observed using a 1$\farcs$0 slit providing a spectral resolution of 1.0 Å and an additional 21 targets were observed using a 1$\farcs$25 slit achieving a spectral resolution of 1.2 Å. Finally, the spectra of J0651+2844 (hereafter, J0651) were obtained using the 800 line mm$^{-1}$ grating coupled with a 1$\farcs$0 slit producing a resolution of 2.3 Å. All the spectra obtained at the MMT provide spectral coverage from 3600 Å to 4500 Å spanning the Balmer series from [H$\gamma$]{} to the Balmer jump.

The four remaining targets were observed using the Fred Lawrence Whipple Observatory’s (FLWO) 1.5m Tilinghast telescope equipped with thewhich we again infer from the models of @althaus13. We note again that the parameters for J0745 are taken from @gianninas14.

In Table \[tab:bin\] we provide the binary parameters based on our updated atmospheric parameters. First, we list the orbital period, $P$, and velocity semi-amplitude, $K$, for each system. Based on these values we compute the mass function of the system. Next, we use the mass function to compute the minimum companion mass, $M_{2}$, assuming an orbital inclination angle of $i = 90^{\circ}$, and the most likely companion mass by taking $i = 60^{\circ}$, except for the three eclipsing systems discussed below. We also provide the merger times for those systems that will merge within a Hubble time. The last two columns provide the orbital separation and the expected


gravitational wave strain. Note that no significant radial velocity variability has been observed for six ELM WDs in our sample and only upper limits on their velocity semi-amplitudes are provided. Consequently, we cannot provide binary parameters for those six systems.

There are three eclipsing systems in our sample: [NLTT 11748]{}, J0651, J0751 [@kaplan14b; @brown11; @kilic14b respectively] for which eclipse modeling provides model independent measurements of the parameters of the system. In particular, the orbital inclination angle and the mass of the secondary can be constrained and we adopt these values as the most likely secondary mass for these three objects. Both J0651 and J0751 have $i\approx 85^{\circ}$ and it is not surprising that the secondary masses derived from modeling their eclipses, $M_{2, {\rm
    eclipse}}$ = 0.50 [$M_{\odot}$]{} and 0.97 [$M_{\odot}$]{}, respectively, areall the ELM WDs with [$\log g$]{} $<$ 6.0 are polluted with Ca. The only exception to this rule is J0818+3536. However, the spectrum of J0818+3536 has a S/N = 17 (see the second panel of Figure \[fg:DA1\]). The noise level in the continuum between [H$\epsilon$]{} and H8 could easily conceal a weak Ca line. It seems therefore that the presence of metals in the lowest mass ELM WDs is a rather ubiquitous phenomenon and possibly linked to the evolution of these objects.

![image](f09.eps)

![image](f10.eps)

In Figure \[fg:plotCa\], we plot the measured Ca abundances as a function of both [$T_{\rm eff}$]{} (top) and the stellar mass (bottom). ELM WDs which also contain helium are shown in red. @kaplan13 suggested that H-shell flashes may mix the interior of the WD subsequently bringing metals back to the surface. We


it happens and as long as it’s not too egregious or a regular habit, I think we can probably all just let it slide, don’t you?

“I’ve noticed that the children’s book world is full of sentimental/boring works that only adults would be interested in. Every time I go to the library, it seems like I come home with at least one book that looked good, but turns out to be about a kid who’s pet died or a bird whose best friend turned out to be a snowball and then melted. Or about how the author grew up in poverty but it’s okay because they liked eating paint. (I am not making that up.)

Kids like books about cheeky toy trains, hoppy bunnies, funny superheroes, or grand adventures. Theya chalking on the University of Michigan Diag Wednesday, March 30. Someone had written #StopIslam and Trump 2016, causing a response from university officials and backlash on social media.

“This is an opportunity to spread love and peace, even with small actions like this,” said Open Principal Meg Fenech. “We can combat hate. Even a kindergartner speaking your thoughts of unity and togetherness, that’s important.”

I read a comment from a man recently on a blog that asserted, possibly somewhat tongue-in-cheek, that the goal of most women is to never work a day in their lives. All joking aside, while it is no doubt possible to find real life examples of such women, I would assert this is not generally true.

I have wanted to comment on women having to register


Properties -> JavaScript option when in a PyDev Project.
Question: What do I need to do (e.g. config wise) to get JavaScript auto completion in Eclipse, when NOT in a JavaScript Project (i.e. when in a PyDev Project)?
Is it possible to add a JavaScript perspective/(I'm not sure what call this exactly...) to a PyDev Project in Eclipse?
I'm very new (2 days) to JavaScript development, so preemptive apologies if the problem/solution is trivial!

A:

To add JavaScript to an existing project convert it to a 'Faceted Project' type and then add the JavaScript facet; to do so go 'Project' > 'Properties'.

A:

You should create a javascript project first and then make it a PyDev project (right click it > PyDev > Set as PyDev project).
Also, if you're starting out, you may want tothat weak and get information out of them. As far as any physical effects, they're too weak to have almost any physical effect,” he said.

Karl Reardon, the Planetworks engineer who performed the tests for CTV News, said that the signals coming from the Wi-Fi units were too low to measure on most equipment.

“It’s so far below any of the standards; it's literally thousand of times below the Health Canada limits. It's comparable and lower than the environment we're exposed to every day when we're outdoors,” he said.

The province’s two largest school districts, Vancouver and Surrey, are hoping to have Wi-Fi installed in all of their schools by the end of next year.

With a report from CTV British Columbia’s Mi-Jung Lee


                 20                                 1.06 (0.72, 1.60)\*   1.13 (0.90, 1.36)     182 (153, 214)\*     11.1 (10.0, 12.4)\*   16.2 (13.8, 18.6)\*
  BMI at initial visit (kg/m^2^)                                             where these associations became inverse in direction. These results suggest that environmental phthalate exposure may alter thyroid hormone parameters in pregnant women. Moreover, our findings indicate that the timing of phthalate exposure during gestation may be important for a pregnant woman's susceptibility to thyroidal disruption.

Three epidemiological studies have previously investigated the potential phthalate-associated alterations in thyroid hormone parameters among pregnant women ([@r24]; [@r28]; [@r30]). Notably, only one of these investigations, which we conducted using pilot data, assessed the relationships using biomarker measurements collected at multiple time points in pregnancy ([@r28]). In that population of pregnant women in Puerto Rico, which used data from two study visits in pregnancy, no statistically significant associations were observed between urinary phthalate metabolites and serum concentrations of TSH or free T~4~ in repeated


18 weeks of gestation ([@r20]; [@r43]). In later pregnancy, maternal thyroid hormones are essential for fetal thyroid homeostasis ([@r21]). Even mild alterations in circulating thyroid hormones in pregnancy may have important implications for fetal health. In pregnant women with normal range free T~4~ and TSH levels, increases in free T~4~ in the first trimester were associated with lower birth weight and an increased risk of small for gestational age ([@r35]). Notably, we observed significant phthalate-associated increases in free T~4~ levels at study visit 1 (first trimester) in the present study.

Our study was limited by the lack of iodine status of our study participants, which is a trace element essential for normal thyroid function ([@r61]). Although recent population-based studies have shown that pregnant women in the United States may88.2%\
& & - & 18.9 &\
& & - & 4798 &\
4 & 0.395 & 236.3 & 71.1 & 92.1%\
& & - & 6.7 &\
& & - & 4780 &\
\
\
\
\

We applied LSSMs with different order AR processes. An LSSM using an AR\[0\] process corresponds to a pure white noise process without any temporal correlation and a flat spectrum. The used Kolmogorov-Smirnov test rejects this model at any level of significance (see table 1). Without loss of generality, $Q$ is set to unity, the mean and variance are set to 0 and 1, respectively. We see that the X-ray lightcurve of NGC 5506 can be well modelled with a LSSM AR\[1\] model, as the residuals between the estimated AR\[1\] process and the measured data are consistent with Gaussian white noise. Fig.3


strand of his own hair and conceal it within a compartment at the top of the staff, which is closed by a round silver screw top. The King will also attach each colour with its own ceremonial Buddha image, and bless each colour with holy water. The ceremony is steeped in Buddhist and Brahmic heritage, it symbolizes and cements the King's role as Chief Kshatriya (กษัตริย์) or Warrior ruler of his realm. It also emphasizes his constitutional role as Head and Chief of the Thai Armed Forces (จอมทัพไทย: Chomthap Thai).

These colours are similar to the Flag of Thailand and therefore are treated like the State Colours of the Commonwealth, but are not lowered to the ground but above it to the tune of Sansoen Phra Barami (the Royaldo not carry colours; this goes back to their formation, when they were used as skirmishers and sharpshooters. While individual units may have had banners or pennants to distinguish themselves from other units, regiments as a whole never needed a full stand of Colours. Today, the two rifle regiments in the British Army, The Rifles and the Royal Gurkha Rifles carry their battle honours on their drums, while the Royal Green Jackets also had theirs inscribed on their cap badge; this tradition is maintained by The Rifles, who wear the Maltese Cross badge of the Royal Green Jackets, inscribed with the regimental honours, as the belt badge. In place of a Regimental Colour, the Gurkhas carry the Queen's Truncheon.

The Sri Lanka Sinha Regiment was the first non-British


tassels, and is mounted on a pike with the usual British royal crest finial. The Army Banner bears the Australian Coat of Arms on the obverse, with the dates "1901–2001" in gold in the upper hoist. The reverse bears the "rising sun" badge of the Australian Army, flanked by seven campaign honours on small gold-edged scrolls: South Africa, World War I, World War II, Korea, Malaya-Borneo, South Vietnam, and Peacekeeping. It was presented to the Army in celebration of its 2001 centennial year.
 In the Canadian Army, Royal Canadian Armoured Corps (RCAC) regiments designated horse guards and dragoon guards, along with the Canadian Special Operations Regiment, have regimental standards. RCAC standards have a crimson field and the CSOR standard has a tan field. RCAC regiments other than horseIn the second and third quarters are horizontal stripes of red, yellow and blue, the colours of the unit's uniforms.

The flag also has the coat of arms of the commander within a wreath, on a background of the colour of his canton. The design of the flag changes with the election of a new pope and the appointment of a new commander.

Hungary

The 120 cm × 140 cm Unit colour of the Hungarian Defence Force is the current regulation colour of all Hungarian Defence Forces units since March 15, 1991. The flag is made of white fibres-satin. The height of the coat of arms with the crown is 57, and the width is 58 cm along with the crown. The coat of arms is made of silk with gold and silver embroidery.
The


those outdoors must stop to render proper courtesies by saluting if in uniform or, if out of uniform, by standing at attention, until "Carry On" is sounded. Marines and sailors driving on base during this time are expected to stop their vehicles and stand at attention until the ceremony is over.

Yacht clubs
Many traditional yacht clubs worldwide also conduct morning and evening colour ceremonies. At 0800 each morning and at sunset during the club's active sailing season the ceremony is performed by the launchmen or harbourmaster.
 First, a bell is sounded as an alert for all members and guests present to stand at attention.
 A cannon is then fired and the national ensign hoisted (or lowered if sunset).
 At the conclusion of the ceremony the most senior officer presentThe content published in Cureus is the result of clinical experience and/or research by independent individuals or organizations. Cureus is not responsible for the scientific accuracy or reliability of data or conclusions published herein. All content published within Cureus is intended only for educational, research and reference purposes. Additionally, articles published within Cureus should not be deemed a suitable substitute for the advice of a qualified health care professional. Do not disregard or avoid professional medical advice due to content published within Cureus.

Introduction
============

Ultrasound is a rapid and non-invasive tool ideal for the imaging of soft tissue infections, and it has been associated with a change in clinician management in 50% of emergency department soft tissue infections \[[@REF1]\]. Necrotizing fasciitis (NF) is a devastating infectious disease process characterized by


this was determined to be beneficial given that many cases of NF do not present with these symptoms. The cadaver model closely mimicked the ultrasound appearance of fluid and gas as seen in actual clinical cases of NF (Figure [1C](#FIG1){ref-type="fig"}-[1F](#FIG1){ref-type="fig"}). The desired location for NF was well maintained even with repeated palpation and sonographic examination. The NF simulation was successfully placed in several anatomic locations as well as at varying fascial depths thereby simulating various clinical scenarios and appearances (Figure [2](#FIG2){ref-type="fig"}).

![Preparation and Results\
A) Setup of the cadaver model showing ultrasound guided needle entry into the desired fascial plane. B) Sagittal ultrasound of the anterior lower extremity of the cadaver model showing needle guidance into the crural fascia; 18 gauge needle (yellow arrowhead), crural fascia (red arrowhead), tibialis anteriordiabetes mellitus, immunosuppression, intravenous drug use, skin injury, peripheral vascular disease, and end-stage renal, pulmonary, and liver disease \[[@REF3],[@REF11],[@REF14]\].

The diagnostic gold standard for NF is surgical exploration with tissue cultures, and its treatment centers around source control through aggressive necrotic tissue debridement, fluid maintenance, and appropriate antibiotic therapy \[[@REF2]-[@REF3]\]. While the laboratory risk indicator for necrotizing fasciitis (LRINEC) score has been shown to be highly specific with a high negative predictive value, newer studies have shown that it is not adequately sensitive \[[@REF16]-[@REF17]\]. Plain radiographs may show thickening of soft tissues and sometimes soft-tissue gas, but they rarely contribute to the diagnosis \[[@REF18]\]. Contrast-enhanced CT scans may be comparable to MRIs, but their utility is limited by the common concurrence of acute kidney injury in this patient population \[[@REF4],[@REF18]-[@REF19]\].


that can help expedite the diagnosis and provide information without delaying patient care \[[@REF11]\].

Since ultrasound imaging can be highly operator dependent, suitable teaching models should be available to properly train clinicians on how to best diagnose and recognize sonographic findings of NF. A mannequin-based model for NF (in addition to plain radiographs and CT scans demonstrating NF) has been shown to improve diagnostic ability of learners; however, this study did not include the use of ultrasound \[[@REF4]\]. To our knowledge, the model described in this manuscript is the first cadaver-based simulation tool to help clinicians learn to diagnose necrotizing fasciitis using bedside ultrasound. The anatomically realistic cadaveric model described in this paper is ideal to expose students and clinicians to NF in a non-urgent situation so that theywith a big mallet and lock me in his stationery cupboard if I ever mention marriage again, I have caught myself, of late, staring at Instagram stories of women with good arms in Vera Wang nude-and light-ivory tulle with hand-finished gold Chantilly lace bodices, being 100% that amazing bitch, and I have thought: “Oh, but could it really hurt?” To cure myself, I scour Mumsnet and Reddit for tales of brides and grooms going fully bonkers in the run-up to their big day. Their insanity keeps me sane. My favourite this year is a bride who wrote to one guest insisting she buy tattoo camouflage cream, as her blue arm inkings would spoil the wedding colour scheme. Another bride sent out a weight chart decreeing anyone over 80kg


died in 991, Willigis became guardian of the minor, thus making him, together with Otto's grandmother, Adelaide of Italy, de facto regent of the Empire until Otto III reached his majority in 994.

In 996 he was in the retinue of the King on his journey to Italy. Together with Otto III he pushed the election of Pope Gregory V against the resistance of the Roman nobility led by Crescentius the Younger and was present at the consecration and at the synod convened a few days later. In this council Willigis strongly urged the return of Bishop Adalbert of Prague, who, unable to bear the conflicts with the Vršovci noble family and the ruling Přemyslid dynasty, had left his diocese for a second time, to which, after much correspondencejust Burchard, who was appointed Bishop of Worms by Emperor Otto III in 1000. Upon the Emperor's early death, Archbishop Willigis on 7 June 1002 crowned the Duke of Bavaria Henry IV as King of the Romans at Mainz, after the assassination of his rival Margrave Eckard I of Meissen. Willigis presided at the 1007 synod at Frankfurt am Main, where thirty-five bishops signed the bull of Pope John XVIII for the erection of the Diocese of Bamberg.

Though Willigis has never been canonized, Roman Catholics celebrate his feast on 23 February, the day of his death in 1011. It has also been alternatively given as 18 April.

Builder

In his diocese he laboured by building bridges, constructing roads, and fostering commerce. In Mainz he initiated the construction of Cathedral and


Q:

How do I get to employer view of Careers?

Possible Duplicate:
What if you have a careers CV but want to post a job as an employer?

I've previously associated my OpenID with semi-finished CV and SO account on Careers. Now I'd like to get an idea of how many developers are available in my area, but http://careers.stackoverflow.com/employer redirects me to my own CV.
Is there a way to search for people from my account, or do I have to use a different OpenID?

A:

You need a second OpenID.
Update:
Duplicates:
Can I be registered on careers.stackoverflow.com as an employer and a candidate?
What if you have a careers CV but want to post a job as an employer?

shootout where the Battery would eliminate their USL Championship rivals.

Like a number of his Battery teammates, Daley represented his country this past season on the international stage. Daley made appearances for the Reggae Boyz during their qualifying run for the 2020 Olympic games. The pacey forward also spent time with the U-20 team, scoring six goals in five matches during the CONCACAF Championships in 2018.

Don't miss out on a chance to be part of history! Purchase your season tickets for our inaugural season at Patriots Point online or by calling (843) 971-GOAL!


Highlight’s Yoon Doojoon will finally be returning to the small screen!

A source from the group’s agency Around Us Entertainment revealed on November 9, “Yoon Doojoon has been confirmed to appear as the lead male role in KBS2’s new drama ‘Radio Romance’ [working title].”

“Radio Romance” explores what happens when a top star who likes to follow a script becomes a radio DJ, and how people become comforted by listening to the radio.

This production will also mark the singer’s first drama role in two years since “Let’s Eat Season 2” and “Splash Splash Love.”

“Radio Romance” is currently in talks to premiere sometime in the first half of 2018.

Source (1) (2)Q:

Are reinventions patentable?

Suppose company A invented X, but kept it a trade secret. If then company B reinvents X, either using reverse engineering, or completely independently, can company B patent it, and if so, can company B enforce that patent against company A?

A:

The two scenarios -- reverse engineering X or independently inventing X -- are significantly different.
Assuming that X was not publicly available, B could very well independently invent X and be granted a patent on it (i.e., "first to file").
In the of X being made publicly available (as a product sold by A), X itself could not be patented by B. However, if the method of making X was novel and non-obvious in view of what was publicly disclosed, B might be able to obtain


DTE's carbon emissions by more than 80 percent by 2050.

DTE Chairman and CEO Gerry Anderson made it clear that the old jobs-versus-environment debate is no longer operational:

"We have concluded that not only is the 80 percent reduction goal achievable – it is achievable in a way that keeps Michigan's power affordable and reliable. There doesn't have to be a choice between the health of our environment or the health of our economy; we can achieve both."

The 80 percent goal will be reached in a series of steps. DTE expects to hit the 30 percent mark by the middle of the next decade. It hopes to hit 45 percent by 2030 and 75 percent 10 years later.

Renewable energy will not entirely drive the transition, but it does plays areliability factor makes grid modernization a vital driver of renewable energy adoption. Accordingly, the new DTE initiative calls for a five-year, $5 billion upgrade that includes its natural gas infrastructure as well as its electric grid. (In addition to its electricity business, DTE has 1.1 million gas customers in Michigan.) In sum, the grid upgrades could put DTE in a good position to outperform its goals on renewables for electricity generation while easing back on its commitment to natural gas.

So, what about small business?

For the foreseeable future, DTE business customers do not have collective bragging rights to 100 percent renewables. However, that goal is in reach individually. Any DTE customer can take a shortcut to bona fide 100 percent renewables by opting into the company's MIGreenPower solar and


to 1 in -4, -0.1, 35, y?
-0.1
Let i = 5870 + -5867. Let d = -11/4 - -13/4. What is the nearest to 0 in d, -5, i?
d
Let l = -0.1792 + 1.1792. Let h = -46 - -48. Let k = -2/63 + 107/63. What is the closest to l in k, h, -4?
k
Let b = -5030.96 - -5031. What is the nearest to 0.1 in 0.5, 1, b?
b
Let b be (2/(-5))/(18/10). Let g = -3439/18551 - -45/1427. Let w = 2.1 - 2. What is the closest to w in b, 24, g?
g
Let o = -0.013 - -25.013. Let t = -56.366 - -55.366. What is the closest to o in t, 1/4, 0.2?
1/4
Let j be (-33)/5*(-59)/177. Which is the closest to -1?  (a) -0.18used for individual and population genetics because of their high abundance, variability, and neutrality \[[@pone.0236483.ref013]\]. For instance, polymorphic loci have been used to distinguish *T*. *rubripes* from *T*. *chinensis* and *T*. *pseudommus* \[[@pone.0236483.ref014]\]. Although microsatellites facilitate examination of genetic variation and genetic structure, tools that use such markers have disadvantages such as inconsistencies in allele size calling caused by use of automatic sequencers and errors in size determination \[[@pone.0236483.ref015]\]. Among the various types of markers in use, single nucleotide polymorphisms (SNPs) are the most abundant in a genome and the most suitable for identification and genotyping \[[@pone.0236483.ref016]\]. Genotyping-by-sequencing (GBS) enables the identification of SNPs for high-throughput screening \[[@pone.0236483.ref017]\]. Compared to next-generation sequencing (NGS), GBS is a simpler and more rapid method for generating SNP data \[[@pone.0236483.ref018]\]. It has


extracted using the DNeasy 96 Blood & Tissue Kit (Qiagen) according to the manufacturer's instructions. DNA was quantified using a NanoDrop ND-1000 instrument (Thermo Fisher, Barrington, IL). The DNA concentration was normalized to 10 ng/μL and used for library preparation.

Analysis of COI gene {#sec004}
--------------------

To analyze genetic variation among the three *Takifugu* species, the polymerase chain reaction (PCR) products of the cytochrome oxidase subunit I (COI) gene in mitochondrial DNA were obtained using the universal primers VF2 (`5′-TCA ACC AAC CAC AAA GAC ATT GGC AC-3′`) and FishR2 (`5′-ACT TCA GGG TGA CCG AAG AAT CAG AA-3′`). The PCR mixture consisted of 1× PCR buffer, 250 μM each dNTP, 2.5 U Ex-Taq DNA polymerase (TaKaRa), 20 ng DNA sample, and 10 pmol universal primers in a total volume ofvarieties. When selecting common SNPs in the same variety, ≤50% missing data were allowed.

A subset of selected polymorphic SNPs was used for validation by Sanger sequencing. Primers were designed to produce 500--600 bp amplicons containing at least one putative SNP using Primer3 v. 2.3.5 \[[@pone.0236483.ref028]\]. Each 20 μL PCR reaction comprised 1× PCR buffer, 2.5 U Ex-Taq DNA polymerase (TaKaRa), 250 μM each dNTP, 10 pmol each SNP marker, and 20 ng genomic DNA template. PCR was performed using an ABI 2720 Thermocycler as follows: 10 min of denaturation at 95°C, 35 cycles (45 s at 94°C, 45 s at 58°C, and 45 s at 72°C) of amplification, and a final extension for 5 min at 72°C. The PCR products were assessed by 2% agarose gel electrophoresis and


purified with Expin PCR SV (GeneAll Biotechnology, Seoul, ROK). The purified PCR products were amplified using an ABI BigDye Terminator v. 3.1 Cycle Sequencing Kit (Applied Biosystems), and run on an ABI 3730XL DNA analyzer (Applied Biosystems). The acquired bidirectional sequences and the reference sequence were aligned in SeqMan software (DNASTAR).

Data analysis {#sec009}
-------------

The COI sequences were assembled using ClustalW multiple alignments with BioEdit software v. 7.2 (<http://www.mbio.ncsu.edu/bioedit/bioedit>), and haplotypes and polymorphisms were analyzed using DnaSP v. 5.1 \[[@pone.0236483.ref029]\]. Genetic relationships were inferred by the maximum-likelihood method with 1,000 replications based on the Tamura-Nei model using MEGA v. 6 \[[@pone.0236483.ref030]\]. Analyses of population genetic structure were assessed to SNP dataset by Bayesian model-based cluster analyses in STRUCTURE v. 2.3.4 \[[@pone.0236483.ref031]\]. The analyses were based on the admixture and correlatedand missing data and 16,577 loci with MAF\> 10% and \<30% missing data were obtained. These SNPs were analyzed common SNP loci referring SNP location common within the same species in integrated SNP matrix of the 96 sample, resulted in 210,656 of *T*. *rubripes*, 141,481 of *T*. *chinensis* and 117,348 of *T*. *pseudomonas* and 159,284 comparable common SNP loci were selected. Among these, 18 polymorphic SNP loci which showed the interspecies polymorphism at the same SNP location among *Takifugu* were selected. Eighteen SNPs were used to construct a maximum-likelihood phylogenetic tree ([Fig 2](#pone.0236483.g002){ref-type="fig"}) with 1,000 bootstraps and a 70% cut-off value among the *Takigufu* groups. *T*. *chinensis* and *T*. *pseudommus* formed one clade. The *T*. *rubripes* clade was separated into their respective taxa excluded three individuals which included


A comprehensive study into the molecular methodology and molecular biology of methanogenic Archaea.
Methanogens belong to the kingdom of Euryarchaeota in the domain of Archaea. The Archaea differ from Bacteria in many aspects important to molecular work. Among these are cell wall composition, their sensitivity to antibiotics, their translation and transcription machinery, and their very strict demands to anaerobic culture conditions. These differences may, at least partly, be responsible for the delay in availability of genetic research tools for methanogens. At present, however, the research within genetics of methanogens and their gene regulation and expression is in rapid progress. Two complete methanogenic genomes have been sequenced and published and more are underway. Besides, sequences are known from a multitude of individual genes from methanogens. Standard methods for simple DNA }
  }

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    if (protoProps) _defineProperties(Constructor.prototype, protoProps);
    if (staticProps) _defineProperties(Constructor, staticProps);
    return Constructor;
  }

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        value: value,
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    for


that you’re choosing the right collaborators to work with. Steps to take include:

Compatibility: Do you see yourself as able to work with the YouTube personalities involved? I mean actually work with them, on a human to human basis. Some YouTubers are quite abrasive. Is that something you want to associate with, or do you think you get along better with someone who are friendlier?

Ideas: There’s absolutely no point going forward with a YouTube collaboration if you don’t have an idea. If you are the person initiating the partnership you are the person who is going to have an idea. Write a script which plays towards both of your strengths.

Offer: I’m willing to bet that you want to work with a YouTube channel that is more famous than youEstre and factory development driver Lars Kern ran four sub-7:00 laps on the day of testing.

That's crazy when you realize that the new GT3 RS only has 20 more horsepower than its predecessor. You can credit those extra 24 seconds to significant chassis upgrades, including much stiffer springs with helper springs, and new solid mountings on both the front and rear subframes. A new Weissach Package also brings optional magnesium wheels, which surely help too. Those wheels wrapped in a new, stickier version of Michelin's Pilot Sport Cup 2 tires, the Pilot Sport Cup 2 R.

And lots of credit has to go to Estre—track conditions were ideal, and he was on it. Just watch the amazing video below.

This content is imported from YouTube. You may be able to


at alees1@hotmail.com for further details or visit his website at http://andrewlees.webs.com/ to discover more of his work. Part of the proceeds from this disk will go to the Center for Whale Research to help fund continued research of the Southern Resident Orcas.

Visit our Website

Contributors

About

This is a public journal and blog for those working at 5 star whale watching. This will provide documentation of the southern resident killer whales, transient killer whales, baleen whales, marine life, birds and nature for your enjoyment. It will also serve as a research data bank for Marine Mammal Research Group and the public.Inc website, it frees up my staff to focus on creating excellent customer experiences.

We were able to complete the whole setup ourselves, it was simple and easy to do, and we didn’t need any custom web development to integrate Meeting Hub with our website.

Alan Arriaga

CEO, Work Inc

We noticed a worrying trend which was a large drop-out rate on our conference room landing pages which previously had an enquiry only form.

Since implementing Meeting Hubs meeting room booking system, we’ve seen that drop-out rate convert into paying customers as they can now search for available meeting rooms, book and pay via credit card straight from our website.

Our meeting room occupancy and utilization rates are up, and so is our revenue since using Meeting Hub.


1. Field of Invention
The present invention relates to a skate, and more particularly to a skate with an adjustable sole plate.
2. Description of the Related Art
Conventional skates have rollers or blades to increase the speed and versatility of the skates. The conventional skate has a boot, a sole plate mounted on the boot and a roller or blade assembly mounted on the sole plate. Most types of skates are a fixed length and width and cannot be adjusted to the sizes of different people's feet, so children need to obtain new skates as their feet grow. The fixed length also necessitates the production of many different sizes. Consequently, the quantity of skates in any given production run is limited. To solve such problems, skates with adjustable sole platesQUETTA, Pakistan (Reuters) - At least nine people died and 21 were wounded when gunmen blasted their way into a police station in southwestern Pakistan on Tuesday while candidates were sitting for a police entrance exam, officials said.

The Pakistani military said a group of three gunmen attacked the entrance of the deputy police inspector’s office in Loralai district in Balochistan, a volatile southern province which has seen a string of militant attacks.

One gunman blew himself up and the others opened fire on police and around 800 candidates taking an exam to join the force, killing three police, five civilian employees and one candidate. Twenty one people including 12 police and nine candidates were wounded.

Soldiers from the army and the Frontier Corps were called in to evacuate the building


and clear the gunmen.

“During the clearance operation, the remaining two suicide bombers have been shot dead and the area has been cleared,” a statement from the military said.

The Pakistani Taliban, also known as Tehrik-i Taliban Pakistan or TTP and which is separate from the Afghan Taliban, claimed responsibility.

Militant violence in Pakistan has fallen sharply from levels a decade ago, but incidents still occur periodically in Balochistan, Pakistan’s largest and poorest province which is at the centre of the strategic China Pakistan Economic Corridor (CPEC) infrastructure development project.

At least four members of the security forces were killed this month in an attack on a Frontier Corps training base in Loralai.muscle performance, e.g., excitation contraction coupling and Ca^2+^ homeostasis^[@CR5]^, a long-term predictor of muscle function is found in structural changes. This is particularly important as skeletal muscle has a high plasticity to respond to exercise with hypertrophy, to disuse with atrophy^[@CR6]^, and to injury with complete regeneration and repair^[@CR7]^. Similarly, muscle structure and cytoarchitecture are also major targets in muscle diseases, such as chronic inflammatory or degenerative diseases associated with ongoing degeneration-regeneration cycles, imperfect repair, and tissue and cellular remodeling. Examples include (poly/dermato-)myositis^[@CR8]^, cancer cachexia^[@CR9]^, muscular dystrophies^[@CR10]^, and even aging^[@CR11]^. Muscle structure remodeling involves not only the extracellular matrix (e.g., fibrosis) but also the remodeling of the sarcomere and the myofibrillar cytoarchitecture. For instance, a hallmark of structural cellular changes as a result of regeneration has been found


ongoing fiber stretch not only resulted in spreading of the sarcomere lengths but, most importantly, in a marked myofibrillar disorder, as reflected by a marked decline in the CAS (Fig. [6c](#Fig6){ref-type="fig"}). In particular, there was a prominent bend of the myofibrillar lattice spacing towards the periphery of the fibers (Fig. [6c](#Fig6){ref-type="fig"}). Lumping together the CAS and VD values for all stretches did not reveal any difference between the wt and *mdx* fibers (Fig. [6f, g](#Fig6){ref-type="fig"}). When stretching fibers, however, one has to keep in mind that with an increasing SL, fewer verniers will remain in the respective field of view. This phenomenon can be compensated for by using a stretch-corrected VD, as described in the Methods. Thus, when correlating CAS and the stretch-corrected VD to the maximum stress values and theSL in all stretched single fibers, Pearson correlations confirmed significant relationships between the SL and the degree of myofibrillar disorder, i.e., a massively declining CAS and an increasing corrected VD (Fig. [7a, b](#Fig7){ref-type="fig"}). Since increasing the SL also means increasing restoration forces and thus increasing maximum stress, the resulting correlations for the maximum stress values corresponded to the SL-CAS/-VD~*corr*~ relationships (Fig. [7c, d](#Fig7){ref-type="fig"}). Thus, these data confirm a marked myofibrillar disorder with stretch, which was similar in the wt and *mdx* fibers and thus was not related to the presence or absence of dystrophin in single EDL fibers.Fig. 6Simultaneous assessment of passive single fiber viscoelasticity biomechanics and SHG myofibrillar ultrastructure in wt and *mdx* EDL muscles.**a** sequence of SHG images (left) taken during a protocol stretching a single EDL fiber


psoas muscle showed no major changes in the filament lengths of actin or myosin within sarcomeres under rigor, isometric contraction or relaxing conditions^[@CR46]^. Using an E-shaped tendon force transducer clamped to a *tibialis anterior* muscle of living mice and applying SHG imaging to an electrically stimulated whole muscle in vivo, a vast increase in the sarcomere length variability was seen as a broadened SL distribution, in particular at short muscle lengths (90° ankle) over long muscle lengths (180° ankle)^[@CR47]^. That very recent study focused on planar images from the top 100 µm and collecting backscattered SHG signals from whole muscle without further details on the 3D aspect of myofibrillar structure under contractile activation; however, it may provide a basis to explain our observed increase in angular disorder of myofibrils if oneSo we need to be able to create a new instance of the
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    let mirror = Mirror(reflecting: self)
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    var keyPaths: [KeyPath<Self, Any?>] = []
    let instance = Self()
    for (key, _) in instance._keyPathReadableFormat {


Q:

Find all elements with a certain attribute value in jquery

I need to find all elements that has a special attribute value.
Here is the div I need to find (I have many of them..)
<div imageId='imageN'>...

I simply need to loop through the divs which have imageId='imageN'

A:

Although it doesn't precisely answer the question, I landed here when searching for a way to get the collection of elements (potentially different tag names) that simply had a given attribute name (without filtering by attribute value). I found that the following worked well for me:
$("*[attr-name]")

Hope that helps somebody who happens to land on this page looking for the same thing that I was :).
Update:
It appears that the asterisk is not required, i.e. based on some basic tests, the following seems to be equivalent to    # Eliminate prefixes that are counted as part of words and break the completion.
        prefix = '' if prefix.slice(-1).match(/(\)|\.|:|;)/g)
        suggestion = @suggestionFor(word, prefix)
        suggestions.push(suggestion)

      return suggestions

    return []

  mapType: (type) ->
    switch type
      when 'Function' then 'function'
      when 'Module' then 'module'
      else type

  dispose: ->


-1/4?  (a) -0.109  (b) -1  (c) -16/3
a
What is the closest to 0 in -1617, -5, -2/11?
-2/11
Which is the nearest to -1/3?  (a) -0.7  (b) -2  (c) 4  (d) -2/5
d
Which is the nearest to 0?  (a) -4  (b) -4/47  (c) -8  (d) 3
b
What is the closest to -2 in -0.3, -4.98, 4, 1/2?
-0.3
Which is the closest to -26?  (a) 3/7  (b) 3  (c) -18  (d) -0.5
c
What is the closest to 2 in -1, 1, 0.2, -0.3?
1
Which is the nearest to -1?  (a) -1  (b) -2  (c) 1  (d) 6
a
What is the closest to -1/4 in 0.34, -1/6, 5, 4?
-1/6
Which is the nearest to -0.8?  (a) 2/19  (b) 2Q:

Javascript/jQuery: Remove item from multidimensional array by value

I have a dynamically generated multidimensional array from which I want to remove a specific value.
I have this code, so far:
mainARR = [[1,2,3,4], [5,6,7,8]];
delARR = [1,2,3,4];

function removeByValue(array, value){
    return array.filter(function(elem, _index){
        return value != elem;
    });
}
mainARR = removeByValue(mainARR, delARR);

console.log(JSON.stringify(mainARR));

I don't know the index of the value I want to remove. Instead, I know the actual value. The code does not work when the value is an array. It works perfectly for simple arrays like [1,2,3,4] when I want to remove, let's say, the value 1.
Any help is appreciated.

A:

If you make the elem and value into a string then your code works just fine.
function removeByValue(array, value) {
  return


in after the unit has been "started".
Also, try to log using print >>os.stderr as output to stdout is buffered and hard to see timing.
You should not have
Environment=NOTIFY_SOCKET=/run/%p.sock
Environment=WATCHDOG_USEC=1000000

as these are set by systemd. You should pass the proxy socket via --env and also the WATCHDOG_USEC as it'll be "lost" otherwise:
ExecStart=/usr/libexec/sdnotify-proxy /run/%p.sock /usr/bin/docker run \
--env=NOTIFY_SOCKET=/run/%p.sock --env=WATCHDOG_USEC=1000000

with regard to cigarettes, which they state to be a danger" (Kaiser Daily HIV/AIDS Report, 3/22). In response to Trujillo's statements, the World Health Organization said that although condoms can be less effective if they slip, break or are expired, a June 2001 review of the available literature on male condoms found that they are 90% effective at preventing HIV transmission if used consistently and properly (Kaiser Daily HIV/AIDS Report, 10/15/03). The Vatican prohibits the use of condoms for both contraception and protection against HIV infection, according to BBC News. Nielson said, "This is where bigotry gets into the big discussion," adding that the Vatican's position shows a "lack of love for human beings" and an "unwillingness to take their situation seriously," according to BBC News. The Vatican


the internal collapse of the system itself. With the crucial exception of Poland, the countries in the old Soviet bloc aren't even Roman Catholic, or are so only partially. Whatever his contribution to that historic set of events, though, the Pope is on the wrong side of history now. Women's equality, sexual rights for all, the struggle of the individual against authoritarian religion and of course the global AIDS epidemic--the Pope has been a disaster on all these crucial issues of our new century. It's all very well for David Brooks to mock those who critique the Pope for his "unfashionable views on abortion," as if 78,000 women a year dying in illegal procedures around the world was just something to chat about over brie and chablis. ButAIDS Day to hammer home the Vatican's position, which has drawn criticism from many quarters.

In a message addressed to Catholics, Cardinal Javier Lozano Barragan, president of the Pontifical Council for Health Pastoral Care, called for new ways of helping people change lifestyles. "We have to present this as the main way for the effective prevention of infection and spread of HIV/AIDS, since the phenomenon of AIDS is a pathology of the spirit...," he said.

The Roman Catholic church opposes artificial contraception -- including condoms, which it says promote promiscuity. The five-page message spoke of the "importance of respecting the religious and moral values of sexuality and matrimony, namely fidelity, chastity and abstinence."

Barragan, who is Mexican, invited "each and every one to step up prevention according to the doctrine of


fact," according to the BBC.

Dr Thomas Quinn, an HIV expert speaking on behalf of the Infectious Diseases Society of America, said several scientific studies show the virus cannot pass through condoms. "The mechanical barrier is 100 per cent except when there are tears or breaks, so they are absolutely incorrect," he said. "They are going to need to come up with scientific proof to prove that statement wrong because there is a multitude of publications that show that the virus cannot pass through the latex of the condom."

Lopez Trujillo had no immediate comment. Last year, the Vatican repeated its opposition to condoms. Monsignor Javier Lozano Barragan, president of the Pontifical Council for Health Workers, acknowledged that to some, the Vatican position may sound "ridiculous in the society inLymphocyte migration into the CNS modelled in vitro.
We report on a series of experiments which examines the factors controlling lymphocyte adhesion to brain endothelium in vitro and the factors which control cell migration across the endothelium, using a new migration assay. Although lymphocyte adhesion preceded migration across the brain endothelium, the two processes are not identical. We noted that activated CD4+ T cells were particularly good at migrating across endothelia. CD8+ T cells and B cells did not migrate but adhered well to endothelia. Moreover, the endothelium maintained high levels of cell traffic without being disrupted and without exhausting the molecular systems which allowed migration. From the viewpoint of migration of dividing cells, the state of lymphocyte activation appeared to be the most important controlling factor--these cells migrated