This adjustment is described in algorithm v1.0. As an example, if the GPS-sampling time delay is 2 seconds, latitude and longitude coordinates are reassigned to CH~4~ readings that were observed two seconds previous.

2.3 Peak detection {#sec005}
------------------

The first step in identifying NG leak indications is to characterize departures from typical levels of CH~4~. We characterize these departures by first defining a baseline (or background) CH~4~ concentration. Atmospheric CH~4~ concentrations are typically around 2 parts-per-million (ppm), but they vary at the small, localized scale where CH~4~ measurements are taken during a mobile survey. Thus, it is necessary to define a baseline concentration as a function of local CH~4~ measurements. We calculated a baseline concentration for each CH~4~ measurement made by the survey instrument.

We updated our baseline calculation methodology between v1.0blowing the plume away from the roadway) and soil conditions (e.g., wet soil preventing the escape of gas). As a result, the leak indications reported from our survey efforts are a subset and not a census of all leaks present in the distribution system. See also Weller et al. \[[@pone.0212287.ref022]\] for a discussion of this phenomenon.

New to algorithm v2.0, we calculate the location of leak indications using a weighted spatial average of the locations of the OPs that compose the leak indication. The location of a leak indication is an estimate of the location of a potential natural gas leak. In algorithm v1.0 we used an unweighted spatial average. Each OP has a maximum recorded CH~4~ concentration and a location associated with this maximum concentration. When OPs are


joined, we average the coordinates of the maximum CH~4~ concentration from each peak. Coordinates with the largest CH~4~ concentrations are given the most weight. We use a weighted average because data from controlled CH~4~ releases showed that, for a given leak size, the largest measured CH~4~ concentrations are more likely to be observed when the vehicle is closest to the expression point. The final estimate of the leak's location is given by: $$\left( {{Long},{Lat}} \right) = \frac{\sum_{j = 1}^{p}w_{j}\left( {{long}_{j},{lat}_{j}} \right)}{\sum_{j = 1}^{p}w_{j}},$$ where w~j~ is the maximum CH~4~ concentration from the j^th^ observed peak and p is the number of OPs that were joined to create the verified peak.

We used a handheld GPS to record the coordinates of leaks during field work in one city to assessthe logistics of driving in an urban area, many roadways are surveyed more than two times. We similarly define a road point as having been driven three times, four times, etc. In the overwhelming majority of cases, road points driven 2+ times have been surveyed on at least two separate days. We estimate the number of miles driven 2+ times by interpolating adjacent road points that were driven 2+ times using ArcGIS. [Table 2](#pone.0212287.t002){ref-type="table"} displays the number of road miles driven and number of survey attempts from two cities.

10.1371/journal.pone.0212287.t002

###### The number of road miles driven by survey effort in two cities.

![](pone.0212287.t002){#pone.0212287.t002g}

                 2     3     4


new year Tuor began a journey west, towards the Ered Lómin mountains, in order to find the Gate of the Noldor, following a small river which he considered to be a sign. With the help of Gelmir and Arminas he passed through the gate and entered the coast known as Lammoth. Further on, he entered Nevrast and became the first of the race of Men to have seen the Great Sea Belegaer.

Lead by swans, Tuor found the city of Vinyamar on the slopes of Mount Taras and from the great halls he took the armor and weapons that Turgon
had left, then climbed down towards the sea once more. There, on the shores of Belegaer, the Valar Ulmo appeared before him and spoke of Gondolin, where Tuor, with the''I just can't get my head around … looking at the ladder and seeing Sydney on top, Adelaide second. I can't get my head around them being the best two sides in the comp - because they're not,'' Malthouse said on 3AW yesterday.

''It's a lot to do with the draw. They're not the best sides.

''If Sydney and Adelaide finish first and second and they knock over [in week one] the next two on the ladder, say it's Collingwood and Hawthorn, then [Collingwood and Hawthorn] will run into Geelong, who've run into some good form, North Melbourne, who've snuck up on people … and West Coast, who are a better side than how they've been playing. You can throw a blanket right over this group at the moment.''

Malthouse said


he considered Hawthorn to be ''a far better side'' than Sydney, despite the Swans having convincingly beaten the Hawks in Launceston in round five. He also said Adelaide, drawn to play Gold Coast and GWS twice as well as local rival Port Adelaide, was benefiting significantly from having finished fourth from bottom last season.

''I'm not saying they're a dreadful side, but … I don't think they're the best side, and they can finish on top of the ladder,'' he said.Metabolic engineering of Pichia pastoris for production of hyaluronic acid with high molecular weight.
The high molecular weight (>1 MDa) of hyaluronic acid (HA) is important for its biological functions. The reported limiting factors for the production of HA with high molecular weight (MW) by microbial fermentation are the insufficient HA precursor pool and cell growth inhibition. To overcome these issues, the Xenopus laevis xhasA2 and xhasB genes encoding hyaluronan synthase 2 (xhasA2) and UDP-glucose dehydrogenase (xhasB), were expressed in Pichia pastoris widely used for production of heterologous proteins. In this study, expression vectors containing various combination cassettes of HA pathway genes including xhasA2 and xhasB from X. laevis as well as UDP-glucose pyrophosphorylase (hasC), UDP-N-acetylglucosamine pyrophosphorylase (hasD) and phosphoglucose isomerase (hasE) from P. pastoris were constructed and tested.


only thing anyone is interested in hearing is "The leak is plugged, the oil has been skimmed, and life is returning to normal." Anything else just backfires and makes BPs image worse.

If I were in BP's shoes, I'd buy ad space and show a live 30-second feed of the rovers, th

Yes. It worked, for the most part, for Exxon and Union Carbide. They'll, probably, just try to play by the play-book those two companies used. History shows that the public has a short memory/attention span.

The Valdez incident was in a fairly unpopulated part of a state with a very small population. Union Carbide was in India, and thus not only a long way off, but impacting foreigners.

This is literally happening in a very populated, economically important region ofthat - people pay to have their links appear when certain terms are searched; that's how search engines make money. Sponsored links aren't the best and most relevant result for your search (and are likely the exact opposite).

I have a friend who does affiliate marketing, and makes a lot of money off of people's dumb search habits, specifically their willingness to click sponsored links, believi

The problem is that they weren't leaving the pump unattended, they were interfering with what the operators thought needed to be done and skimping on materials. Had they just been leaving it unattended, we probably wouldn't be in the current mess. But then again BP has a substantial history of fucking things up, and has yet to actually learn anything from past experience.

You're out


Renesas signs up for PowerVR SGX graphics coreNews & Analysis 3/31/2006 Post a commentImagination Technologies Group plc, a licensor of graphics processor designs, has said that Japan’s Renesas Technology Corp. has licensed one of the PowerVR SGX graphics and video processing core family members under a multiple-use license arrangement.

Commentary: Qimonda has to cope with uncertaintyNews & Analysis 3/31/2006 Post a commentDespite the fact that the memory business was considered Infineon's problem child, Qimonda, the memory subsidiary of the German chip giant set to begin operations on May 1, has a chance to make its way in the memory market. But there are still many uncertainties to overcome, not least surrounding its still uncertain initial public offering of shares.

Opto to surpass discrete ICs in 2006News & Analysis 3/30/2006 PostSign up for our COVID-19 newsletter to stay up-to-date on the latest coronavirus news throughout New York City

BY ARTHUR S. LEONARD | The standard rule in family law is that the legal spouse of a woman who gives birth to a child is presumed to be the child’s legal parent. Traditionally, that meant that when a married woman gave birth, her husband was accepted as the father. The doctrine was developed to ensure that children were not subjected to the legal status of illegitimacy.

In some states the parental presumption is incontestable, while in New York and elsewhere it can be overturned if evidence of another man being the biological father is produced.

Applying this presumption and its traditional underpinnings to a same-sex married couple is not a precise fit,


Monroe County Supreme Court Justice Joan Kohout in Rochester, during a separation that began in late 2011, Ms. C began a relationship with Mr. M., which she has acknowledged led to her becoming pregnant with J.C. In fact, after the infant was born, by which time Ms. C was back together with her wife, she allowed the biological father two visits with their daughter.

Shortly after the second visit, Mr. M. filed his paternity suit, seeking genetic testing to confirm J.C. is his daughter and also to deny Ms. S the right to claim access to the child other than that afforded voluntarily by the biological mother.

Ms. S was with her wife when she gave birth to J.C., “selected the child’s name and signed her birth certificate,” according toarguments, specifically saying that marriage between two women changes the equation.

“With the advent of same-sex marriage, the role of the non-biological spouse, especially in a marriage of two women, requires a re-examination of the traditional analysis of the presumption of legitimacy,” the judge wrote. “Most of the cases to date concerning same-sex couples involve children born of artificial insemination where female spouses have planned together to raise the child.”

Kohout noted that sperm donors are usually anonymous so “there is no legal father.”

Responding to Ms. C’s argument about the parental presumption, the judge wrote, “the Marriage Equality Act does not require the court to ignore the obvious biological differences between husbands and wives.” Even though the 2011 law “requires same-sex married couples to be treated the same as all


from the patient's body and are detectable by nuclear imaging instruments and reflect, for example, blood flow or metabolic function in the organ.
In order to calibrate and check the accuracy of nuclear imaging instruments, test structures, known in the field as phantoms, are utilized. Other prior nuclear imaging phantoms have been produced in forms which encase radioactive sources within a structure which simulate the shape and gamma ray attenuation properties of the human body. Such conventional test phantoms may employ concentrated radioactive sources which are imaged as “hot” spots or small non-radioactive structures within a homogenous radioactive source which exhibit “cold” spots in the image produced. The nuclear imaging instruments are used to produce images of the phantom. By examining the images produced, the degree to which theline, and each point on the line has an [X,Y] coordinate on the map. However, each [X,Y] coordinate on the map does not have a position on the line. Another way to look at this is … consider the rainbow. Can you find brown in it? Not really. But there’s brown in RGB space. Revision History August 11, 2016 Add information about chakra systems and Alexander Scriabin. August 8, 2016 Add the Color of Sound chart in collaboration with Nicholas “Nexdrum” Melendez.

Add caveat section. October 9, 2012 Added a note about the issues of converting RGB colors to frequencies. Version 1.02 — December 12, 2010 Overhaul to improve colors, fix black colors, and add onChange() events to all inputs. Version 1.01 — December 11, 2010 Initial release.


certainly open discussion and changes would
be recommended. Perhaps even a list of recommended public figures that are
well-aligned with the philosophy.

I know that Steve Jobs, for example, is Zen Buddhist. But Buddhism is one of
those things (if I understand correctly) that isn't necessarily considered a
"religion" and people are also encouraged to change it to their own likings.
For example, I believe a lot of Buddhist concepts (4 truths), but I don't
believe in reincarnation at least in the physical sense. I believe that
reincarnation means someone goes through mental changes, and metaphorically
become a different or new person through mental and psychological changes.

Sort of thinking out loud on this. Some of it may make no sense.

~~~
siong1987
You can actually ask me more about Buddhism. In my country, we have actually 4
different main religions: Buddhism,Islam, Hinduism, and Christianity. Most of
the Chinese here believe in Buddhism. Here, Buddhism is really a religion.

But, I agree with what you have said. You can actually extend what you believe
or refuse what you don't believe in basically every religions as long as you
"believe" that you are actually doing the right thing.

So, is "belief" actually a religion?

~~~
jmtame
Siong, did you take the HIST120 class yet? It look at Buddhism, Daoism, and
Confucianism. Very interesting, of the three I was a biggest fan of Buddhism.

~~~
siong1987
This is my first semester. But, is it an easy A? I need some As to pump up my
CGPA.

~~~
jmtame
It's not bad, lots of reading though.


the simplicial complex is a $O(\frac{1}{d^2})$-local-spectral expander. So, the reduction of Oppenheim is basically lossless in the regime where Kaufman-Oppenheim’s \[t:KO\] applies.

### Analyzing Mixing Times of Markov Chains {#analyzing-mixing-times-of-markov-chains .unnumbered}

Recently, Anari, Liu, Oveis Gharan, and Vinzant [@AnariLOV18] found a striking application of \[t:KO\] and \[c:opp\] in proving the matroid expansion conjecture of Mihail and Vazirani [@MihailV87], answering a long standing open question in Markov chain Monte Carlo methods.

To illustrate their result, consider the special case of sampling a random spanning tree from a graph $G=(V,E)$. Let $X$ be the simplicial complex where the ground set is $E$ and each acyclic subgraph of $G$ is a face of $X$. Then $X$ is a pure $d$-dimensional simplicial complex, where $d = |V|-2$ and the spanning trees of $G$ are the maximal\in \Ii$ and $T \subset S$, then $T \in \Ii$,

-   (extension property) if $S, T \in \Ii$ such that $|S| > |T|$ then there is some $x \in S\backslash T$ such that $\set{x} \cup T \in \Ii$.

A partition matroid is the special case where the ground set $E$ is partitioned into disjoint blocks $B_1, \ldots, B_l \subseteq E$ with parameters $0 \leq d_i \leq |B_i|$ for $1 \leq i \leq l$, and a subset $S$ is in $\Ii$ if and only if $|S \cap B_i| \leq d_i$ for $1 \leq i \leq l$.

The intersection of two matroids $M_1 = (E, \Ii_1)$ and $M_2 = (E, \Ii)$ over the same ground set $E$ can be used to formulate various interesting combinatorial optimization problems [@Schrijver03]. We are interested in


a parameter $\lambda > 0$, the problem is to sample an independent set $S$ with probability $\frac{\lambda^{|S|}}{Z_G(\lambda)}$ where $Z_G(\lambda) := \sum_{S \subset V: S {\rm~independent}} \lambda^{|S|}$ is the partition function. An important work of Weitz [@Weitz06] gave a deterministic fully polynomial time approximation scheme to estimate $Z_G(\lambda)$ for $\lambda$ up to the “uniqueness threshold”, but the exponent of the runtime depends on the maximum degree $\Delta$ of $G$. It is conjectured that the natural Markov chain for sampling independent sets mixes in polynomial time up to the uniqueness threshold. Anari, Liu, and Oveis Gharan prove this conjecture and obtain a polynomial time algorithm to estimate $Z_G(\lambda)$ up to the uniqueness threshold for any graph (even with unbounded maximum degree). They consider a pure $n$-dimensional simplicial complex for sampling independent$X_{\alpha}$. More explicitly, each singleton $\{v\}$ in $X_{\alpha}$ is a vertex $v$ in $G_{\alpha}$, each pair $\{u,v\}$ in $X_{\alpha}$ is an edge $uv$ in $G_{\alpha}$, and the weight of $uv$ in $G_{\alpha}$ is equal to $\Pi_1^{\alpha}(\{u,v\})$. A simple observation is that if $X$ is a pure $d$-dimensional simplicial complex and $\Pi$ is the uniform distribution on $X(d)$, then for any $\alpha \in X(d-2)$ the weighting $\Pi_1^{\alpha}$ on the edges of $G_{\alpha}$ is uniform. We will use this observation in \[sec:sampling\].

Local Spectral Expanders {#ss:local-spectral}
------------------------

### Random Walk Matrices {#random-walk-matrices .unnumbered}

The definition of local spectral expanders will be based on the random walk matrix of $G_{\alpha}$. Let $\Aye_{\alpha}$ be the adjacency matrix of $G_{\alpha}$. Let $\Dee_{\alpha}$ be the diagonal degree matrix where $\Dee_{\alpha}(x,x) = \sum_{y} \Aye_{\alpha}(x,y) = 2\Pi_0^{\alpha}(x)$ where the last


\[eq:onestep\] satisfies this condition with $c_k = 1/(k+2)$.

\[thm:oppenheim\] Let $(X,\Pi)$ be a pure $d$-dimenisonal weighted simplicial complex where $\Pi$ satisfies \[eq:onestep\]. For any $0 \leq j \leq d-2$, if $G_\alpha$ is connected for every $\alpha \in X(j-1)$, then $$\gamma_{j - 1}\le \frac{\gamma_j}{1 - \gamma_j}.$$

An inductive argument proves the following corollary.

\[cor:oppenheim\] Let $(X,\Pi)$ be a pure $d$-dimenisonal weighted simplicial complex where $\Pi$ satisfies \[eq:onestep\]. If $G_\alpha$ is connected for every $\alpha \in X(k)$ and every $k \leq d-2$, then $$\gamma_j \le \frac{\gamma_{d - 2}}{1 - (d-2- j)  \cdot \gamma_{d-2}}.$$

Higher Order Random Walks {#sec:updown-defn}
-------------------------

### Up and Down Operators {#up-and-down-operators .unnumbered}

Let $(X, \Pi)$ be a pure $d$-dimensional weighted simplicial complex. In the following definitions, $\alpha \in X(k)$, $\beta \in X(k+1)$, $\eff \in \RR^{X(j)}$, $\gee \in \RR^{X(k+1)}$, and $j \in \{-1,0,\ldots,d-1\}$.

Thea bound on the second eigenvalue of the $d$-th down-up walk based only on the maximum second eigenvalue of the graphs in dimension $d-2$. This will be useful in \[sec:sampling\].

[corollary]{}[maincooked]{}\[cor:main-cooked\] Let $(X, \Pi)$ be a pure $d$-dimensional weighted simplicial complex. For any $0 \leq k \leq d$, suppose $\gamma_k \leq \frac{1}{k+1}$ and $\gamma_j < 1$ for $-1 \leq j \leq k-2$, then $$\lambda_2(\DownW_k) = \lambda_2(\UpW_{k - 1}) \le 1 - \frac{1}{(k+1)^2}.$$

Since $\gamma_{k-2} \le \frac{1}{k+1}$ and $\gamma_j < 1$ for $-1 \leq j \leq k-2$, it follows from Oppenheim’s \[cor:oppenheim\] that for any $-1 \leq j \leq k-3$, $$\gamma_j \leq \frac{\gamma_{k-2}}{1-(k-2-j)\cdot \gamma_{k-2}}
    \leq \frac{\frac{1}{k+1}}{1-\frac{k-2-j}{k+1}}  = \frac{1}{j+3}.$$ Therefore, by \[thm:main\], $$\begin{aligned}
        \lambda_2(\DownW_k)


$\DownW_{j+1}$ and $\UpW_j$ have the same non-zero eigenvalues. By \[lem:updownrel\], $\NUpW_{j+1} \preceq_{\Pi_{j+1}} \gamma_{j} \Ide + (1-\gamma_{j}) \DownW_j$, and thus for $-1 \leq r \leq j$ the matrix $\NUpW_{j+1}$ has at most $|X(r)|$ eigenvalues with value greater than $$\gamma_{j} + (1 - \gamma_j) \cdot \parens*{ 1 - \frac{1}{j + 2} \prod_{i=r}^{j-1} (1 - \gamma_i) }
    = 1 - \frac{1}{j+2}\prod_{i=r}^{j} (1 - \gamma_i).$$ Using the definition of the \[eq:nupw-def\], we have that for $-1 \leq r \leq j$, $\UpW_{j+1}$ has at most $|X(r)|$ eigenvalues with value greater than $$\frac{j+2}{j+3} \left( 1 - \frac{1}{j+2}\prod_{i=r}^{j} (1 - \gamma_i) \right) + \frac{1}{j+3}
    = 1 - \frac{1}{j+3} \prod_{i=r}^{j} (1 - \gamma_i).$$ For $r = j+1$, it is trivial that there at most $|X(j+1)|$ eigenvalues greater than $\frac{j+1}{j+2}$ since$S_{t+1}$ to be a uniform random common independent set of size $k$ that contains $S_t\setminus \{i\}$. The stationary distribution of $\DownW_{k-1}$ is the uniform distribution $\Pi_{k-1}$; see \[eq:stationary\].

The main result in this subsection is the following upper bound on the second eigenvalue of $\DownW_{k-1}$.

### Proof of \[t:matroid\] {#sss:proof}

The plan is to use \[cor:main-cooked\] to prove \[t:matroid\]. To apply \[cor:main-cooked\], we need to prove that:

1.  $C_{M_1, M_2, k}$ is a pure simplicial complex. This is a simple proof in \[prop:mint-pure\].

2.  For each $S \in C_{M_1, M_2, k}$ with $|S| \leq k-2$, the random walk matrix $\Emm_S$ of the graph $G_S$ of the link $(C_{M_1,M_2,k})_S$ satisfies $\lambda_2(\Emm_S) < 1$. This is proved in \[lem:connected\], showing that the underlying graph of $G_S$ is the complement of the line graph


(E, \Ii_2)$ be two matroids with a common independent set $T \in \Ii_1 \cap \Ii_2$ of size $|T|=r$. Any common independent set $S \in \Ii_1 \cap \Ii_2$ with $|S| < r/2$ is contained in a larger common independent set. In particular, this implies that the simplicial complex $C_{M_1, M_2, k}$ is a pure simplicial complex as long as $k \le r/2$.

By the extension property of matroids, there is a subset $T_1 \subset T$ with $|T_1| \geq r-|S|$ such that $S \cup \set{x}$ is an independent set in $\Ii_1$ for any $x \in T_1$. Similarly, there is a subset $T_2 \subset T$ with $|T_2| \geq r-|S|$ such that $S \cup \set{y}$ is an independent set in $\Ii_2$ for any $y \in T_2$. As $|S| < r/2$, this implies that    \Ide),&&\textrm{ (by the \ref{eq:var-form})}\label{eq:refer-later2}
\\
        &~\le~\norm*{\Dee_H^{-1}} \cdot (|\lambda_{\min}(\Aye_L)| -
        1),&&\textrm{ (by using $\lambda_1(-\Aye_L) = -\lambda_{\min}(\Aye_L)$)
        }\notag
\\
        &~=~\norm*{\Dee_H^{-1}}.&&\textrm{ (by using \cref{fac:lg-eigbd})}\label{eq:last-mint}\end{aligned}$$ For \[eq:refer-later2\], we have used the \[eq:var-form\] $\lambda_1(\Why) = \max\set*{\langle \eff, \Why \eff\rangle : \eff \in \RR^V, \norm{\eff}= 1}$ in the following way: Let $\Why = -\Aye_L - \Ide$ and $\gee$ be an unit top-eigenvecor of $\Dee_H^{-1/2} \Why \Dee_H^{-1/2}$, i.e. $\norm{\gee} = 1$ and $\langle \gee, \Dee_H^{-1/2} \Why \Dee_H^{-1/2} \gee\rangle = \lambda_1(\Dee_H^{-1/2}\Why \Dee_H^{-1/2})$. Then, $$\lambda_1(\Why)
\ge \left\langle \frac{\Dee_H^{-1/2} \gee}{\norm{\Dee_H^{-1/2} \gee}}, \Why
        \frac{\Dee_H^{-1/2} \gee}{\norm{\Dee_H^{-1/2} \gee}}\right\rangle
= \frac{\lambda_1(\Dee_H^{-1/2} \Why\Dee_H^{-1/2}) }{\norm{\Dee_H^{-1/2}g}^2}
\ge \frac{\lambda_1(\Dee_H^{-1/2} \Why\Dee_H^{-1/2})}{\norm{\Dee_H^{-1}}}.$$

It remains to


The outbreak of war in 1939 put people living and working in various
British colonies at risk. This was especially so after Japan entered
the war in December 1941 and threatened to invade countries such
as Malaya and Hong Kong. In order to protect these people, the British
government decided to evacuate many of its officials from several
colonies.

Evacuation started in 1940. The first people to be evacuated were
the wives and children of British officials serving in the colonies.
The officials themselves were left behind so that they could continue
to run the colony and were not evacuated until the country was threatened
with immediate invasion. In total, the British government estimated
that by 1942 over 2,000 people had been evacuated from Hong Kong
and over 9,000 from Malaya.

Very few of the evacuees from the Colonies were sent---------------------- Forwarded by V Charles Weldon/HOU/ECT on 02/13/2001
03:17 PM ---------------------------

Sanjeev Khanna@ENRON
02/13/2001 03:25 PM
To: Maria Garza/HOU/ECT@ECT, V Charles Weldon/HOU/ECT@ECT, Mark
Breese/HOU/ECT@ECT, Eric Moon/HOU/ECT@ECT, Michelle Zhang/HOU/ECT, Edith
Cross/HOU/ECT@ECT
cc:
Subject: Check your coworkers

In the Birmingham Sunday Mercury (7th Jan 2001)

  Worker Dead at Desk For 5 Days

     Bosses of a publishing firm are trying to work out why no one noticed
  that one of their employees had been sitting dead at his desk for FIVE
DAYS before anyone asked if he was feeling okay.

     George Turklebaum, 51, who had been employed as a proof-reader at a New
  York firm for 30 years, had a heart attack in the open-plan office he
  shared with 23 other workers. He quietly


football tournament twice, in 1924 and 1928, before the creation of the World Cup. Uruguay also won the 1980 Mundialito, a tournament among former World Cup champions. In total, Uruguay have won 20 official titles, a world record for the most international titles held by any country.

Their success is amplified by the fact that the nation has a very small population of around 3.4 million inhabitants (2011 est.). Uruguay is by far the smallest country in the world to have won a World Cup in terms of population, 1.75 million inhabitants in 1930. The second-smallest country, by population, to have won the World Cup is Argentina with a population of nearly 28 million people in 1978. Uruguay is also the smallest country ever to win any World CupF.C. one, in the unofficial debut of the national team v Argentina in 1901. Then Uruguay worn a variety of shirts, including a solid green one and even a shirt with the colors of the flag of Artigas.

On 10 April 1910, now-defunct club River Plate defeated Argentine side Alumni 2–1, being the first time an Uruguayan team beat that legendary team. That day River Plate wore its alternate jersey, a light blue one due to the home jersey was similar to Alumni's. Ricardo LeBas proposed Uruguay to wear a light blue jersey as a tribute to the victory of River Plate over Alumni. This was approved by president of the Uruguayan Association, Héctor Gómez. The light blue (Celeste) jersey debuted in a Copa Lipton match v Argentina on


SEE NEW POSTS

Texas Lt. Gov.: Grandparents aren't afraid to die to get economy going again Dan Patrick, Texas’ Republican lieutenant governor, on Monday night suggested that he and other grandparents would be willing to risk their health and even lives in order for the United States to “get back to work” amid the coronavirus pandemic. “Those of us who are 70 plus, we’ll take care of ourselves. But don’t sacrifice the country,” Patrick said on Fox News’ “Tucker Carlson Tonight.” Read the full story here. Share this -

Hospitals limiting visitors in delivery rooms Mothers-to-be spend months perfecting their birth plans. And while births often don't go according to those plans, most women find comfort in knowing they have support — and at least one person advocating for theirMost of the exterior building lights at Paris Las Vegas, including on its 50-story replica Eiffel Tower, are turned off except for the marquee as parts of the Las Vegas Strip go dark as a result of the statewide shutdown on March 19, 2020. Ethan Miller / Getty Images The coronavirus pandemic has caused a wave of restaurant, bar and casino closures across the country, as state officials from California to Vermont have scrambled to reduce large gatherings of people to limit the spread of COVID-19. According to the American Gaming Association, at least 973 commercial and tribal casinos — or 98 percent of all gaming properties in the United State — have closed, directly affecting about 649,000 casino gaming employees. Nevada Gov. Steve Sisolak's statewide order last


the league. Without Bowman in the middle to pressure the quarterback, Willis’ responsibilities will increase and he may not physically be able to do what is asked of him.

Chances he makes the roster:

100%.defined by the magnitude of the negative vector sum of all transverse energies measured in calorimeter cells, corrected for the transverse energy of isolated muons and for the different response to electrons and jets. A more detailed description of objects reconstruction can be found in [@Abachi:2007:prd].

The final selection in the $e\mu$ channel requires that the scalar sum of the leading lepton $p_T$ and the $p_T$ of the two most energetic jets be greater than 110 GeV. To reject background in $ee$ and $\mu\mu$ events, where  arises from mismeasurement, we compute a  significance which takes into account the resolution of the lepton and jet measurements. We require the significance to exceed five standard deviations. In the $\mu\mu$ channel, events are furthermore required to have ${\mbox{\ensuremath{E\kern-0.6em\slash_T}}\xspace}> 40$ GeV.

The  signal is modeled using the


  Statistical uncertainty          0.33   -0.35

  : \[tab:systematics\_f\] Summary of uncertainties on $f_{\mathrm{meas}}$.

![\[fig:fc\_f\] (Color online) For all channels the 68.0% (inner), 95.0% (central), and 99.7% (outer) C.L. bands of $f$ as a function of $f_{\mathrm{meas}}$ from likelihood fits to MC events. The thin yellow line indicates the most probable value of $f$ as a function of $f_{\mathrm{meas}}$, and therefore represents the calibration of the method. The vertical dashed black line indicates the measured value $f_{\mathrm{meas}}=0.74$.](FC_f){width="50.00000%"}

To estimate the expected uncertainty on the result, ensembles of MC experiments are generated for different values of $f$, and the maximum likelihood fit is repeated, yielding a distribution of $f_{\mathrm{meas}}$ for each generated $f$. Systematic uncertainties are included in this procedure,taking correlations between channels into account. We then apply the “ordering principle” for ratios of likelihoods [@fc_limit] to the distributions of $f_{\mathrm{meas}}$ and generated $f$, without constraining $f_{\mathrm{meas}}$ to physical values. The resulting allowed regions for different confidence levels as a function of $f_{\mathrm{meas}}$ and $f$ are shown in Fig. \[fig:fc\_f\]. From the maximum likelihood fit to data, we obtain $$f_{\mathrm{meas}} = 0.74^{+0.40}_{-0.41} \, ({\text{stat+syst}}) \,\,.$$ The simultaneously extracted  cross section is found to be $${\mbox{${\sigma}_{t\bar{t}}$}\xspace}= 8.3 ^{+1.1}_{-0.9} \, ({\text{stat+syst}})  \ \, {\text{pb}}$$ for $m_t=172.5$ GeV and in good agreement with the SM prediction of ${\mbox{${\sigma}_{t\bar{t}}$}\xspace}= 7.46 ^{+0.48}_{-0.67} \ \,
{\mathrm{pb}}$ [@SMtheory_MochUwer]. The comparison of $f$ for prediction and data with the fitted result is shown in Fig. \[fig:D\_template\]. The measured fraction is consistent with the SM expectation ($f=1$) and we exclude the


exercise regularly in order to stop new fat cells from being produced.

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With the incentives for Conto Energia now closed and the incentives for other forms of renewable energy nearing their limit of €5.8 billion per year at €5.634 billion as of 31 January 2016, a further €166 million per year remained to be distributed amongst non solar PV renewable energy sources.

Conto Termico
The conto termico was introduced by ministerial decree on 28/12/12. It provides incentives for renewable energy production as well as efficiency savings in the heating and cooling sector. The total value of the incentives available are €900 million per year with payments lasting 2–5 years.
The fund is divided into €200 million


me. You cannot pay me personally enough funds to go back to senior high school or be a teen. As far as Mister Jones, nicely, he had been right I’d an intense eating disorder and I also was not going to give in to be able to anyone as well as eat in which candy bar. All things considered it was the one thing I sensed I had treatments for.

Most nights I felt that My partner and i lived exterior my body and it was so very significantly alone, plus it seemed in which my father has been the only person that may see through myself. He would point out, “You are different Alex which world does not like those who are in contrast to them. Do notby price and availability. Artwork is also usually selected by a small subset of the people who will actually view the artwork
Content creators are varied and numerous. Typically, they create a digital work and provide it to consumers at a purchase price. However, many content creators lack the technical abilities to reach a greater number of potential consumers as well as the ability rent or lease their content.
Therefore, what are needed are superior systems and methods for displaying and controlling centralized content.


/*
 * This Source Code Form is subject to the terms of the Mozilla Public
 * License, v. 2.0. If a copy of the MPL was not distributed with this
 * file, You can obtain one at http://mozilla.org/MPL/2.0/.
 * Copyright (c) Swan & The Quaver Team <support@quavergame.com>.
*/

namespace Quaver.Shared.Config
{
    public enum OrderMapsetsBy
    {
        Artist,
        Title,
        Creator,
        DateAdded,
        Status,
        BPM,
        TimesPlayed,
        RecentlyPlayed,
      been requested by WorldMarkets users, or simply added ‘because they can.’ No doubt, if it turns out to be a popular feature, it will be popping up on your favorite trading platform soon.

CEO and Founder of Celsius Network, Alex Mashinsky, wants to bring the next 100 million people to the blockchain. How? Through high-interest cryptocurrency savings accounts with no lock-up or penalties for withdrawing your HODLings, low-interest USD loans using crypto as collateral–and correcting our ‘bad financial habits’.

EARN INTEREST ON YOUR BITCOINS

If you’re HODLing your BTC or ETH stash, waiting for the next bull run, the Celsius Network proposal is what Mashinsky calls a “no-brainer.”

As the inventor of VOIP (Voice Over IP) technology, a serial entrepreneur, and part of the “one-tenth of the one percent,” Alex hasn’t always


fire and theft: This insurance cover would be dealing with the matters of third party along with the compensation of replacements and repairs. In case your car is stolen or it is destroyed by fire then your damage will be covered.

Comprehensive: It is known as the highest level of the insurance cover, that you can get from the car insurance. This insurance cover will be focusing on the damage that is caused to your car due to accidents. It also involves other people, sometimes they will also include the courtesy car and the legal expenses insurance.

Sometimes you can be required by the insurer to add the name of the driver with in the insurance policy. But you have to make sure that the name you have given shouldYear: 2011

Vitamin B5, also known as pantothenic acid, is a water soluble vitamin considered essential to well-being. It is needed to synthesize and metabolize proteins, fats and carbohydrates amongst other important enzymes. It is found in a range of food products including cereals, legumes, eggs and meats and may be used as an ingredient in personal… Read more »

It’s that time of year again: when we at PhaMix wish our followers and customers the warmest winter holidays. By the time you read this, we will be fully occupied giggling into our eggnog lattes. No doubt you are employing your time just as wisely. You can’t go wrong over the holidays if you follow… Read more »

Ferulic acid, as found in apothekari Phloretin + C Antioxidant Serum, works to


better positive predictive value, odds ratio, and detection. Despite the relative (\>33%) or absolute change (\>12.5 mL) combination definition was most used in recent studies, the preferred cutoff for clinically significant HE has not reached a consensus. Thus we believe mathematically or clinically optimal cutoffs could be validated, not only to lower the heterogeneity among studies, but also to better stratify high-risk patients.

HE presents the extended distribution of initial hemorrhage, including ventricle invasion, transition or rebleeding into compartments adjacent to the initial zone and intraparenchymal volume growth. HE occurs in about 73% of patients within 3 hours from symptom onset and clinically prominent expansion occurs in 35% of patients \[[@R13], [@R22], [@R23]\]. However, the pathophysiology of HE remains unclear and needs further investigation. Previous studies have proposed severalin which the preference for ID speech decreases temporarily; and Stage 3, in which older infants again show a consistent preference for ID speech. For the native/non-native speech pair, there is a tendency for an increased preference for native speech over non-native speech, although infants did not demonstrate a U-shaped pattern. The difference in developmental pattern between the two types of speech pairs was discussed.


of personal jurisdiction in this case is North Carolina's long-arm statute, which allows the exercise of personal jurisdictions to the limits allowed by due process. See Dillon v. Numismatic Funding Corp., 291 N.C. 674, 231 S.E.2d 629 (1977). Thus, if the exercise of personal jurisdiction in this case comports with due process, as outlined in Burger King and its progeny, personal jurisdiction will lie in this case. See Burger King Corp. v. Rudzewicz, 471 U.S. 462, 105 S.Ct. 2174, 85 L.Ed.2d 528 (1985). "[T]he constitutional touchstone [of this due process inquiry is] ... whether the defendant purposely established `minimum contacts' in the forum." Id. at 474, 105 S.Ct. 2174. See also Hardee's Food Systems, Inc. v. Beardmore, 169 F.R.D. 311, 314 (E.D.N.C.1996) (discussing minimum contacts in the franchiseare not so isolated or attenuated that an exercise of personal jurisdiction would offend due process. Defendants entered into multiple agreements with a North Carolina corporation which required a continuing relationship with that corporation. The agreements clearly indicated that Plaintiff Hardee's was a North Carolina corporation with its principal place of business in North Carolina. Each agreement, furthermore, contained a North Carolina choice-of-law provision. Pursuant to those agreements, the Defendants paid monthly royalty and advertising fees to Hardee's in North Carolina and submitted monthly royalty reports to Hardee's in North Carolina. Finally, Defendants' alleged refusal to make contractually-required payments to Hardee's caused injury, if at all, to Plaintiff in North Carolina. Cf. Burger King Corp., 471 U.S. at 480, 105 S.Ct. 2174.
Therefore, Defendants have purposely established "minimum contacts"


with North Carolina such that personal jurisdiction exists in that state. Consequently, this Court must deny Defendants' Motion to Dismiss for lack of personal jurisdiction.

*770 2. Venue

A. Propriety of Venue in the Eastern District of North Carolina
Defendants argue that the Eastern District of North Carolina is an improper venue for this action, pursuant to 28 U.S.C. § 1406(a). In diversity actions, venue is appropriate in "(1) a judicial district where any defendant resides, if all defendants reside in the same State, (2) a judicial district in which a substantial part of the events or omissions giving rise to the claim occurred, or a substantial part of the property that is the subject of the action is situated, or (3) a judicial district in which any defendant is subjectZhang Yun Ying is a perfect specimen of grandmother, with bright white hair and profound wrinkles that get better when she smiles. But it’s her stride that really hits you -- how she balances on her heels like a kid. She can't help it: like most women who grew up in China when she did, Zhang's feet were bound until she couldn't walk straight anymore.

A photograph of Zhang's feet, courtesy Jo Farrell.

We know this because of another woman, Jo Farrell. For nearly a decade, the British photographer -- who bills herself as a documentarian of endangered “traditions and cultures” -- has visited Zhang in her home in a small village in China annually, snapping portraits each time. As the years have passed, Farrell has met and photographed other


Q:

When using sudo to run pip "pip: command not found" but it's installed

sudo easy_install pip
Searching for pip
Best match: pip 1.4.1
Processing pip-1.4.1-py2.7.egg
pip 1.4.1 is already the active version in easy-install.pth
Installing pip script to /home/nyzlfc/.local/bin
Installing pip-2.7 script to /home/nyzlfc/.local/bin
Using /home/nyzlfc/.local/lib/python2.7/site-packages/pip-1.4.1-py2.7.egg
Processing dependencies for pip
Finished processing dependencies for pip

And then when I run
sudo pip install -U pyyaml nltk

I get:
sudo: pip: command not found

A:

If you install pip from the Ubuntu repositories pip will work with sudo (I have used pip this way on 12.04 through to 14.04).
sudo apt-get install python-pip

A:

Your pip is installed in /home/nyzlfc/.local/bin, which is not in the sudo path and with a good reason. Just add ~/.local/bin to your path and step away of sudo as it's unnecessary.

A:

I had the same problem, and the reason I had this problem (onJust like strncmp, but the second argument must be a literal string
   and you don't specify the length.  */
# define STRNCMP_LIT(S, Literal)                        \
  strncmp (S, "" Literal "", sizeof (Literal) - 1)

/* Whether Literal is a prefix of S.  */
# define STRPREFIX_LIT(Literal, S)              \
  (STRNCMP_LIT (S, Literal) == 0)

//#include <unistd.h>
//#include <inttypes.h>

# ifndef UINTPTR_MAX
/* This isn't perfect, but it's good enough for Bison, which needs
   only to hash pointers.  */
typedef size_t uintptr_t;
# endif

/* Version mismatch. */
# define EX_MISMATCH 63

/*---------.
| Gnulib.  |
`---------*/

//#include <unlocked-io.h>
# include


   </uap:InitialRotationPreference>
      </uap:VisualElements>
    </Application>
  </Applications>
  <Capabilities>
    <Capability Name="internetClient" />
    <uap:Capability Name="picturesLibrary" />
    <uap:Capability Name="videosLibrary" />
    <DeviceCapability Name="webcam" />
    <DeviceCapability Name="microphone" />
  </Capabilities>
</Package>Category Archives: Stuff that winds me up

WHY WERE THEY ALLOWED BACK INTO THE UK IN THE FIRST PLACE??? Shutting the gate after the horse has bolted, comes to mind Difficult enough housing the local population and ex servicemen and women Send back to their last port … Continue reading →

THEY FORGOT TO ADD, WHO IS PAYING THIS “THE BRITISH TAXPAYER” Revealed: The £75,000 annual bonuses paid out to half of NHS consultants as Jeremy Hunt demands more reform days after forcing them to work weekends There are 43,475 consultants … Continue reading →

WHO IS THIS ASSHOLE? I TOTALLY MISSED THIS ONE (July 2014) A COUNCILLOR who called soldiers “hired killers” on Armed Forces Day breached the council’s code of conduct, a panel has ruled Ben Duncan said he


subsidizing multi-million-pound Ministry … Continue reading →

BBC Newsnight / The Bureau of Investigative Journalism Military charity Help for Heroes has been criticized by some of the UK’s worst-wounded troops for spending money on buildings rather than everyday care. They claim the recovery centers are not always … Continue reading →

Petition Background (Preamble) Isimeli Baleiwai known as ‘Bale’ to his friends is facing deportation from the UK after serving 13 years with the British Armed Forces. Bale is a foreign and commonwealth soldier from Fiji who was recruited by the … Continue reading →

This is an old one but well worth reviving it again (October 2008) A retired Royal Marine has been fined for having a replica badge printed on his car number plate to recognize his service tois the success sequence they know and they are sure their kids are going to follow," he said, noting that those closest to them would disapprove of any other path.

In addition to the economic divide in our view of marriage and child-bearing, there has been a cultural shift as well, and Hollywood has played its part in this. "Kim Kardashian is only 'Exhibit Z,'" Mr. Wilcox said.

"She can afford to do this," he said. "The sad reality is that most women can't afford it, and their kids suffer."

Social scientists have ascribed a long list of ills for children born outside a stable marriage: They are more likely to live in poverty, more likely to fail in school, less likely to go to college and achieve status jobs, more


World's First Underwater Hotel Residence To Open In Maldives

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A luxury resort in the Maldives is set to open the world's first undersea villa, offering guests the chance to sleep with the sharks in a dream-like, watery marine setting.

In the race to bag the title of world's first undersea residence the Conrad Maldives Rangali Island looks to be in the lead, having announced that its US $15 million residence The Muraka will open later this year.

Named after the local Dhivehi word for coral, the residence will span two levels, with the lower space featuring a king size bedroom, living area, bathroom and spiral staircase that leads to the upper floor.

Guests sleep 16 feet (five meters) below sea level with 180-degree panoramic views of the Indian Ocean and its inhabitants:about $400 from insurance company.  The second time was less of a hit but a truck so it really scraped it due to height differences.   The field service guy the insurance sent out saw the damage and then said let me check the padding under the bumper.
It was damaged/cracked which negates much of the damage control from the bumper unit.   BUT this was probably done on the first accident.   That insurance and their shop only was going to pay for the bumper cover not replacing the whole bumper unit.   This was $400 compared to $1100 (including paint/install).   The second guy was honest the first wasn't and neither was the shop.
So he


    be    sufficient    to

establish    by    clear     and   convincing    evidence        that,    but   for

constitutional error, no reasonable factfinder would have found the

petitioner guilty of the offense.            28 U.S.C. § 2244(b)(2) (2000).

Easter’s    claims     do    not   satisfy    either   of    these       criteria.

Therefore, we deny authorization to file a successive § 2254

petition.

         fact, I will go on record now as being profoundly anti-murder. However, one cannot deny the sheer brilliance it took to pull this off. I can only imagine what this man would have been capable of had he used his powers for good rather than evil. This illustration is intended to supplement books and podcasts on the topic and to help people visualize how the hotel that Holmes built might have looked and how it was used.


design power supply system using close to final services, and the Detector Control System (DCS). To demonstrate the functionality of the pixel detector system a stepwise transition was made from the normal laboratory readout and power supply systems to the ones foreseen for the experiment, with validation of the data obtained at each transition.'
address:
- 'University of Wuppertal, Gaußstr. 20, 42097 Wuppertal, Germany'
- 'University of Bonn, Nussallee 12, 53115 Bonn, Germany'
author:
- Joachim Schultes
- 'Karl-Heinz Becks'
- Tobias Flick
- Tobias Henß
- Martin Imhäuser
- Susanne Kersten
- Peter Kind
- Kerstin Lantzsch
- Peter Mättig
- Kendall Reeves
- Jens Weingarten
title: Validation Studies of the ATLAS Pixel Detector Control System
---

,

,

,

,

,

,

,

,

,

, and

ATLAS ,Pixel ,Detector Control System (DCS) ,System Test ,Power Supplies ,Interlock System

The Atlas Pixel Detector {#PixDet}
========================

The pixel detector of the ATLAS experiment is the innermost part ofin a total number of just over 80 million readout channels.

![Scheme of detector module[]{data-label="fig:Module"}](Module.eps){width="\columnwidth"}

Each detector module (Figure \[fig:Module\]) consists of 16 frontend chips which are connected to the associated sensor cells. The readout and control of the frontend chips is provided by the Module Controller Chip (MCC). The analog part of the frontend chips is separately supplied, while their digital part is supplied together with the MCC. During operation of a detector module, it is also necessary to provide a depletion supply channel for the sensor. In addition, the detector module will have a thermistor (NTC[^1]) which is used to provide temperature information for each detector module. This thermistor, with a related interlock circuit [@Interlock], is used to prevent damage to the hardware due to high temperatures.

The Read


a functional approach. Once the physically connected hardware is connected to the DCS using the FIT, the SIT will create a virtual image of the detector inside the DCS. This image will then be used to navigate through the detector’s geographical structure and to monitor and control the relevant data. The system therefore allows for operation of the DCS without deeper knowledge of the physical cabling, which was also tested at the system test.

The DAQ-DCS Communication {#DDC}
-------------------------

During the experiment, the DAQ[^19] system will not only be responsible for taking physics data but also for starting and stopping of runs. On the other hand, DCS has to react correspondingly to ensure correct detector operation. Therefore it is necessary to synchronize the DAQ system with DCS.

For the synchronisation DDC[^20] willWal-Mart announced plans Wednesday to enter the District for the first time, laying out an aggressive strategy to open four stores and hire 1,200 people in the city by 2012.

The blueprint is part of a national effort by the chain to expand beyond rural and suburban areas, where its low prices and massive stores transformed the retail landscape, into urban markets. Although Wal-Mart already operates stores in Northern Virginia and suburban Maryland, it has never had a store in the District.

The four stores would be built in D.C. neighborhoods where retail options are relatively scarce: on the site of a former car dealership on Georgia Avenue NW; at New York Avenue and Bladensburg Road NE; as part of a new mixed-use development on New Jersey Avenue NW; and


experiment is:
$$ S = A \ \times B = \{(x,y):x \in A \ \land y \in B\}$$
The number of possible outcomes is
$$ |S|=|A|\cdot|B|=100 \cdot 99=9900 $$
For question (a): Let $ C $ be the set of the defective semiconductor chips that are defective. The event of interest is:
$$ K = \{(x,y)\in S:x\in C \ \land y\in B \}=C \times B $$
The probability of $ K $ is (assuming uniform probability measure):
$$ \Bbb P(K)=\frac{|K|}{|S|}=\frac{|C| \cdot|B|}{|A| \cdot |B|}=\frac {|C|}{|A|}=0.2 $$
For question (b):
Let $ U $ be the set that contains all the elements of S where the second selected item is defective. The probability of interest is:
$$ \Bbb P(U|K)= \frac{\Bbb P(U \cap K)}{\Bbb P(K)} $$
We know $ \Bbb P(K) $ but we don't know the value of thejudge.

In a statement read out in court, the dead man's daughter Melissa Bland eviscerated him.

"You are stupid, a stupid boy who never learned from his mistakes," she said.

"You are a little coward with no sense of integrity or responsibility.

"You are now a convicted killer. I hope you think about it every night before you go to sleep. You took the life of a great man."

Trevor Bland's partner, Kim Robinson, who suffered fractures to her face, eye socket, ribs, sternum and spine in the crash, also had a statement read.

"You destroyed a big part of my life and left me broken. You will get to walk free, live again in the future. Trevor gets nothing. He is now ashes and you did that to him. I hope every day


   formatted_wmi_object = self._format_property_values(previous_wmi_object, current_wmi_object)
                yield formatted_wmi_object
        else:
            #  No format required
            for wmi_object in self._current_sample:
                yield wmi_object

    def __getitem__(self, index):
        """
        Get the specified formatted WMI Object from the current sample.
        """
        if self.is_raw_perf_class:
  Create a new WMI connection
        """
        self.logger.debug(
            u"Connecting to WMI server (host=%s, namespace=%s, provider=%s, username=%s).",
            self.host,
            self.namespace,
            self.provider,
            self.username,
        )

        additional_args = []

        if self.provider != ProviderArchitecture.DEFAULT:


          item = CaseInsensitiveDict()
            for prop_name in self.property_names:
                item[prop_name] = None

            for wmi_property in res.Properties_:
                # IMPORTANT: To improve performance, only access the Qualifiers
                # if the "CounterType" hasn't already been cached.
                should_get_qualifier_type = (
                 u"CounterType qualifier not found for %s.%s", self.class_name, wmi_property.Name
                        )

                try:
                    item[wmi_property.Name] = float(wmi_property.Value)
                except (TypeError, ValueError):
                    item[wmi_property.Name] = wmi_property.Value


  searchBar = (EditText)findViewById(R.id.searchBar);
    }

fetch method:
    public void fetch(View v){                                              //onClick in xml starts this "fetch" method

        String w = searchBar.getText().toString();                          // get the text the user enters into searchbar
        String finalURL = head.trim() + w.trim() +Characterization of the first-order visual interneurons in the visual system of the bumblebee (Bombus terrestris).
The bumblebee (Bombus terrestris) has become a common model animal in the study of various aspects of vision and visually guided behavior. Although the bumblebee visual system has been studied to some extent, little is known about the functional role of the first visual neuropil, the lamina. In this work, we provide an anatomical and electrophysiological description of the first-order visual interneurons, lamina monopolar cells (LMCs), of the bumblebee. Using intracellular recording coupled with dye injection, we found that bumblebee LMCs morphologically resemble those found in the honeybee, although only the LMC type L1 cells could be morphologically matched directly between the species. LMCs could also be classified on the basis of their light


a history of aborted cardiac arrest, documented ventricular tachycardia or fibrillation, and syncope. While 75% of patients had normal standard echocardiograms, 54 patients (25%) had at least one abnormal echocardiographic finding. Most common were subclinical cardiomyopathic changes, including increased left atrial volume index (n = 25), left or right ventricular enlargement (n = 7), and grade I-II diastolic dysfunction (n = 7). Left atrial volume index was higher in LQTS patients with arrhythmic events compared with those without (24.4 ± 5.5 mL/m(2) vs. 22.3 ± 6.1 mL/m(2) , P =.02). Corrected QT intervals and left atrial volume index correlated significantly albeit weakly (r(2) = 0.04, P <.01). Concomitant congenital heart disease was found in two patients. Subclinical cardiomyopathic changes were found in nearly 20% of LQTS patients. Left= j - p. List the prime factors of v.
2, 3
Let r = 21 - -199. Suppose -l + r = 4*l. Suppose l = -f + 5*f. List the prime factors of f.
11
Let g be (2/(-1) - 0) + 0. What are the prime factors of 0/5 - 5*g?
2, 5
Let b = -4 + 6. Suppose 4*v = b*v + 38. What are the prime factors of v?
19
Let v(w) = -5*w**3 - 12*w**2 - 13*w - 9. Let m(s) = -3*s**3 - 6*s**2 - 7*s - 4. Let i(p) = 7*m(p) - 4*v(p). List the prime factors of i(6).
2, 13
Let r = -19 - -118. List the prime factors of r.
3, 11
Suppose r - 3 - 6 = 0. Let g = 6 - r. What are


+ 20. Suppose 2*v = v + d. List the prime factors of v.
2, 5
Let b(f) = 2*f + 1. Let l be b(-2). Let r be (-2 - l)/((-1)/(-19)). What are the prime factors of r + -2 + -4 + 3?
2
Suppose 0 + 12 = 4*z. Suppose 3*a - z*f = 54 - 18, -5*a + 53 = 2*f. List the prime factors of a.
11
Let o(q) = -q**2 - 10*q - 11. Let x be o(-8). Suppose 0 = 4*r - x - 11. What are the prime factors of r?
2
Let u = 4 + -3. Suppose 2*d + 3*b - u = 0, -2*d = -d - 3*b - 5. Suppose -5*g + 54 = -c, 4*g - 44 = -d*c + 3*c. List thechromosome movement \[[@B17],[@B18],[@B42]-[@B45]\], but no physiological data were presented. More recent evidences that implicate myosin function in anaphase chromosome movements are based on experiments using various inhibitors of myosin or inhibitors of myosin phosphorylation \[[@B1],[@B21],[@B22],[@B46]\]. In particular, movement of chromosomes during anaphase is stopped or slowed by the myosin inhibitor 2,3-butanedione monoxime (BDM) \[[@B1],[@B16],[@B21]\] or by the Rho-kinase inhibitor Y27632 \[[@B1]\]. Our present experiments utilise Calyculin A (CalA), a compound which prevents myosin dephosphorylation.

In order for non-muscle and smooth muscle myosin to be functional, the regulatory light chain (RLC) of myosin must be activated by phosphorylation by specific kinases, either myosin light chain kinase (MLCK) \[[@B47]-[@B49]\] or Rho-kinase (Rho-K) \[[@B40],[@B50]-[@B52]\], and possibly others \[e.g. \[[@B53]-[@B55]\]\]. Myosin homeostasis is achieved by the balance between activation by phosphorylation, and inactivation


the 3 half-bivalent pairs are from one cell in which LatB had no effect and 1 of the 3 pairs is from a cell in which LatB slowed chromosome movement

To further test whether the effect of CalA on anaphase is due to its action on myosin, we double treated cells with CalA followed by BDM made up in CalA solution. BDM, a myosin inhibitor that acts directly on phosphorylated myosin and inhibits its motor activity \[[@B93]\], stops or slows chromosome movement in crane-fly spermatocytes when added during anaphase \[[@B1],[@B21]\]. When we added 5 mM BDM to CalA treated cells as the chromosomes started to accelerate their poleward movement, the chromosomes slowed down or stopped (Table [3](#T3){ref-type="table"}; Fig. [4C](#F4){ref-type="fig"}). The chromosomes resumed their accelerated movement after washing out BDMthan those in normal cells and are wavy (Fig. [6B,B\'B\"](#F6){ref-type="fig"}). Microtubules also seem to leave the kinetochore bundle by detaching at the kinetochore end and \"peeling off\" at an angle (Fig. [6B,B\',B\"](#F6){ref-type="fig"}), which is never seen in control cells. In control prometaphase spermatocytes, the kinetochore microtubule bundles are thinner and much less prominent than at metaphase because of the more abundant non-kinetochore microtubules. In prometaphase cells treated with CalA, kinetochore microtubules are not seen (Fig. [6C\'](#F6){ref-type="fig"}), i.e., the microtubules do not end at the kinetochore, and there seem to be fewer non-kinetochore microtubules than in control cells. Thus it appears that the chromosomes lost their kinetochore attachment to the microtubules, which would explain how they were able to rotate in the spindle. In some of the CalA-treated spermatocytes


cells were analysed from images time-lapsed from the DVDs using Virtual Dub \[[@B113]\] as described in \[[@B114]\]. Graphs were plotted using SlideWrite.

Competing interests
===================

The author(s) declare that they have no competing interests.

Authors\' contributions
=======================

JT made the initial observations on the effects of Calyculin A on several anaphase cells while working as a summer NSERC student. LF did the rest of the experimental work, did the bulk of the writing and the preparation of the final manuscript. AF conceived the study, treated some cells with calyculin, participated in the design of the study and analysis of the data, and edited the manuscript.

Supplementary Material
======================

###### Additional file 1

Movie representing meiosis I in control crane-fly spermatocyte. Two half-bivalent pairs (out of the total three) are in focus. After the autosomes reached the poles, thePhysical function computer adaptive test outcomes in diabetic lumbar spine surgical patients.
Diabetes is a highly prevalent comorbid condition among patients undergoing spine surgery. Several studies have used legacy patient-reported outcome measures to implicate diabetes as a predictor of increased disability, pain, and decreased physical function and quality of life following spine surgery. The effect of diabetes on postoperative physical function has not yet been studied using the PROMIS Physical Function Computer Adaptive Test (PF CAT). To understand the effect of diabetes on physical function outcomes among patients undergoing lumbar spine surgery, as reported by the PF CAT. A retrospective cohort study was performed at a single university-based spine clinic. Patients who underwent lumbar spine surgery between October 1, 2013 and April 26, 2018 with both PF CAT and


1. Field of the Invention
This invention relates to the recording of audio on the sound tracks of video or film and more particularly for a system and method for combining a translation of the original audio into another language while maintaining such original audio at an audible level and with the translation properly positioned relative to the original audio.
2. Discussion of the Prior Art
Various techniques are used in the prior art for providing a translation of a video or film sound track into another language. The most common methods are dubbing, i.e. substituting audio in the second language for that of the original and the use of subtitles. In dubbing, the original speech of the actors is lost completely and along with it much of the flavor andA novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa.
Recently, mutations in several genes have been identified as being responsible for the pathogenesis of autosomal recessive retinitis pigmentosa (arRP). These genes include rhodopsin, beta-subunit of rod cGMP phosphodiesterase (PDEB), alpha-subunit of rod cGMP phosphodiesterase (PDEA), and alpha-subunit of rod cGMP-gated channel. We here attempted to identify a novel mutation in the PDEB gene in Japanese arRP patients. Using the PCR-SSCP method, sequencing analysis, and restriction endonuclease digestion assay, we analyzed the PDEB gene in 17 Japanese families with non-dominant retinitis pigmentosa. A novel Ile535Asn mutation was identified in two patients in a single family and the mutation cosegregated with RP in this family. Among


90 unrelated healthy individuals, no one was identified as homozygous for this mutation, except for one individual who was found to be heterozygous. Isoleucine at codon 535 in the PDEB gene is conserved among various mammals. Missense mutations of the PDEB gene causing arRP have been reported in a limited region (codon 527-codon 699) in which codon 535 is located. Thus, the Ile535Asn mutation is an additional missense mutation which is responsible for the pathogenesis of arRP.Q:

How to construct a database diagram using phpmyadmin?

hi everyone i have a question. there is a database in phpmyadmin that include a lot of tables which are connected to everyone almost. is there some mean so that i can have the diagram of all of the tables which are connected to each other
Thnx in advance

A:

You can't do this in phpmyadmin... You need to use some external tool.
Try:
MySQL Workbench:
http://dev.mysql.com/downloads/workbench/

When you choose your OS and download type mysql site will take you to one page where it asks you to login/register this is not required, there is link beneath that it says "» No thanks, just start my download!"

Export your database (structure only export) and use "Reverse Engineer Database" mode.


skull have indicated that a machete may have been used by his attacker or attackers to murder him."

After beating Ali in 1981 in an unanimous decision in the Bahamas, Berbick went on to win the WBC heavyweight title fours years later in a decision over Pinklon Thomas.

His reign was short, however, as a 20-year-old Tyson knocked out Berbick in the second round Nov. 22, 1986, to become the youngest heavyweight champ.

He fought from 1976 to 2000, finishing with a record of 50-11 with one draw and 33 knockouts. He also fought for his Caribbean homeland at the 1976 Montreal Olympics.

Following his retirement from the ring, Berbick was convicted in the U.S. for sexual assault, grand theft and burglary.

"We have our challenges in life, but Trevor seemed to handleapp drawer via a simple swipe-up gesture. The handsets will also come with Google Duo for video calling pre-installed.

Availability :

Surprisingly, Google will be offering the Pixel and Pixel XL exclusively through Verizon in the United States, though you can also purchase the handset unlocked from Google Store. The unlocked 5-inch Pixel has been priced at $649 for the 32GB variant, while the 5.5-inch Pixel XL is priced at $769 .The handsets will go on sale from October 20th in most of the key markets of the world including the United States and Europe.

The Pixel and Pixel will be available in Quite Black, Very Silver, and an exclusive Really Blue color.

Pre-orders for the phone starts from today in United States, Australia, Canada, UK, and Germany. In India, pre-orders for


deterioration in PO2 after bypass [to 25(6)% of baseline 3 h after bypass] whereas low responder animals showed recovery of oxygenation after the first hour postbypass and improved to 80(8)% of baseline at 3 h. Changes in adhesion molecule expression serve as a marker of neutrophil activation during cardiopulmonary bypass. The percentage of activated neutrophils in the circulation within 3 h after cardiopulmonary bypass may be predictive of an ongoing inflammatory process that is linked to pulmonary dysfunction.store. We've got collectible styles that adults will love, as well as cute cartoon ones for kids. A comprehensive in-car solution, controlled The Avis App is provided by Avis Rent A Car System, LLC, 6 Sylvan Way Parsippany, NJ 07054, Tel. 3. But one company is developing an infrared iPhone accessory Benefits of My Smart Remote With MSR when you start your car engine and heater/AC and if any thief wants to take away such a car by unlocking its doors (such as by breaking the window or through any other means, then the car will automatically switch off for such a user when he attempts to take away the car. Speed of movement or rotation depends on how much you tilt the device. Since 1985, RC Car


Action has been the world's #1 RC magazine. Toyota launched an app-controlled, car-sharing service today in Honolulu called Hui. com/2017/05/24/sphero-ultimate-lightningDisney and Pixar's Cars 3 comes out in theaters on June 16, but if you can't wait for that sweet, animated automotive drama, you can bring the action home with the Ultimate Lightning McQueen app The DeskPets app also has the website name on the bottom of the control page, where it can be accidentally tapped, and will then rip you out of the app and send you to Safari. ispytank. All the principles discussed are based on chassis engineering applied to large race cars. Answered Nov 11, 2017 · Author has 599 answers and 757. Mi Remote is a multi-purpose IR remote app, compatible with a wide varietyyour car’s ‘secret port’ and starts fetching all the information to their computer just before your eyes, thus you wonder ‘what kind of sorcery is this?’Toyota launched a Honolulu car-sharing service that allows customers to use smartphones to unlock and start cars for rent by the hour or day. autoblog. Sphero Darkside Black Red 1B01BV3 Sphero Darkside Black Red 1B01BV3 Buy Now At Amazon $63. This is our Team App homepage. e. 5/5(13)Windows Phone Controlled Car using Arduino - TechNet https://social. 99. A smart vehicle is able to optimize its performance to reduce RC Car Setup is the ultimate app to manage your setup actions and your setup sheets of your RC Car. The ultimate control Leap over the competition and your camera app and adjust Viper SmartStart


which the video image of an Android device can be displayed on the KENWOOD Multimedia Receiver and can be controlled from an Multimedia Receiver's touch panel. Buy Now, Pay Later on DAB Digital Radio Tuner App controlled DAB receiver for vehicles without DAB radio SMARTDAB USB port for device charging SMARTDAB APP CONT Like us on Facebook. You can Power levels, interior climate control and location can all be managed with the app – which will also remotely open the car doors with a single tap. Watch video · As far as THE fastest RC car available for sale is concerned, it is the Traxxas XO-1 Supercar. I first became aware of the remarkable road safety benefits of reducing traffic speeds while researching a project for the NSWprices, including cheap rc drift cars, rc buggy, gas rc cars, rc car parts, electric rc cars and all kinds of amazing remote control cars online shopping from GearBest. Explore a range of different designs, from colourful sports cars to powerful monster trucks. Make sure to stock up on some batteries, rechargeable batteries or nitro gas with your order! Scroll down and check out some the hottest remote control cars on the market! SIGN UP. Pair your phone to your HC …11/07/2018 · Toyota recently launched an innovative car-sharing program that is controlled through a mobile app and aimed toward "round-trip" drives to the beach, for …Racer interactive r/c car this high speed race car is controlled by iPod,iPhone or iPad only certain devices work for this item


and, of late, parts of Sub-Saharan Africa – a volatile mix of youth unemployment, social and economic exclusion, lack of genuine democracy – in short, governance deficits. A situation now complicated by skyrocketing food prices which today are higher by 2% compared to the peak of the global food crisis in 2008.

In the world we live in – the world of the Internet, Twitter and Facebook – the people, especially the young, are all too aware of opportunities closed, of freedoms denied and aspirations thwarted by elites who are tempted to promote their own interests over the general good.From Avenue Bourguiba to Tahrir Square, like Eastern Europe in 1989, the people are against political systems that leave limited legitimate avenues for expressing discontent; but to take grievances ontoof the AfDB, it is a tremendous honour to lead this great institution, to lead talented men and women in the management team and staff of the Bank. I thank you, Mr. Chairman, the Bureau, Governors and the Governments you represent, for your constant support, our Board of Directors, management and staff for their dedication.

I thank eminent persons who joined us today, my predecessors, sister institutions, partners in the business world, and civil society for our mutually beneficial collaboration. It is an enormous honour and pleasure to work with you all.Together we are a force for good.


morphology of the NPs was analyzed by scanning electron microscopy. NPs suspended in water were dropped on a carbon tape and air-dried at room temperature in a fume hood or a desiccator. Samples were then coated with platinum for 2 minutes in vacuum and viewed by field emission scanning electron microscopy (S4800, Hitachi, Japan) at an acceleration voltage of 1--5 kV.

### Particle size analysis

A qNano size analyzer (Izon Sciences, Christchurch, New Zealand) coupled with an air-based variable pressure module (VPM) was used for the size determination of NPs using 200 nanopore and 200 nm calibration particles. NPs and calibration particles (5 µL) were suspended separately in 1,000 µL of Izon Tris buffer electrolyte and sonicated for at least 30 minutes prior to use. Each recorded measurement was based(No 2009-0083538).

**Disclosure**

The authors report no conflicts of interest in this work.

![Schematic illustration of NPs preparation.\
**Notes:** Time-NPs and pH/Time_NPs were prepared with Eudratig RS100 and mixture of Eudratig FS30D:Eudragit RS100 (1:1 w/w), respectively, using O/W emulsion method supplemented by sonication while pH-NPs were prepared with Eudratig FS30D without sonication.\
**Abbreviations:** NPs, nanoparticles; pH/Time_NPs, Eudratig FS30D/Eudratig RS100_NPs; O/W, oil-in-water; pH-NPs, Eudratig FS30D_NPs; Time-NPs, Eudratig RS100_NPs.](dddt-9-3789Fig1){#f1-dddt-9-3789}

![Morphology and size distribution of NPs.\
**Notes:** (**A**) SEM images of NPs (scale bar =500 nm). (**B**) qNano size histogram of NPs.\
**Abbreviations:** NPs, nanoparticles; SEM, scanning electron microscopy; pH_NPs, Eudratig FS30D_NPs; Time-NPs, Eudratig RS100_NPs; pH/Time_NPs, Eudratig FS30D/Eudratig RS100_NPs.](dddt-9-3789Fig2){#f2-dddt-9-3789}

![In vitro drug release profiles of NPs.\
**Notes:** Drug release profiles of pH_NPs, Time_NPs and pH/Time_NPs at pHs 1.2, 6.5, and 7.4 resembling stomach, early small intestine, and ileum and colon pHs,


amount of budesonide in the stomach. Although pH--NPs retain the drug in stomach and early part of the GI tract, complete drug release occurs at ileum (pH \>7). The premature drug release can result in drug loss and systemic absorption in the stomach and small intestine before reaching the colon. In contrast, pH/Time_NPs can prevent the premature and complete drug release in acidic and alkaline pH harsh conditions of the GI tract and efficiently deliver the drug to sites of colitis.\
**Abbreviations:** GI, gastrointestinal; NPs, nanoparticles; pH_NPs, Eudratig FS30D_NPs; Time_NPs, Eudratig RS100_NPs; pH/Time_NPs, Eudratig FS30D/Eudratig RS100_NPs.](dddt-9-3789Fig9){#f9-dddt-9-3789}

######

Physicochemical characteristics of NPs

  Formulations   Particle size (nm)   Polydispersity index   Loading efficiency (%)   Encapsulation efficiency (%)   Yield (%)
  -------------- -------------------- ----------------------COSHOCTON - Formal charges have been filed against a man who was threatening people over the weekend with a knife at the Coshocton McDonald's.

The Coshocton County Sheriff's Office said Nicholas L. Hayes, 22, of Coshocton, was charged on Tuesday with attempted aggravated robbery, a second-degree felony. Additional charges are pending further review of the case by the Coshocton County Prosecutor's Office.

The sheriff's office said at about 11:15 a.m. Saturday Hayes was threatening people inside the restaurant with a knife. James H. Bartlett, 70, from Kentucky, was in the restaurant at the time and confronted Hayes in an attempt to protect customers and employees, authorities reported.

Bartlett had a concealed carry permit and drew his weapon while ordering Hayes to drop the knife. He refused to comply and started to


leave the store. Bartlett followed Hayes outside and eventually convinced him to drop the knife. The sheriff's office credits Bartlett's actions with allowing deputies to peacefully take Hayes into custody once on scene without any injuries or loss of life.for the collection of personal information, the sale of personal information or the deletion of personal information. It may also offer a different price, rate, level, or quality of goods or services to the consumer if that price or difference is directly related to the value provided to the consumer by the consumer’s data. In either of these cases, the consumer must affirmatively opt in to these financial incentives, after receiving a notice that meets certain specific requirements.

Operational Changes

The CCPA also requires Business Entities to provide a privacy policy, which it must update at least every 12 months, describing:

The consumer’s rights under the CCPA, together with one or more methods for submitting requests;

A list of the categories of personal information it has collected about consumers in the preceding


personal information deletion, including arguably broader rights to request deletion under the CCPA and different exceptions under the two laws;

The CCPA also includes arguably broader rights to access personal information held by a Business Entity than does the GDPR and does not provide all of the exceptions available under the GDPR; and

The CCPA includes more stringent restrictions on sharing personal information for commercial purposes than does the GDPR.

Therefore, it is unlikely that compliance with the GDPR will necessarily result in compliance under the CCPA. Business Entities that are GDPR-compliant must carefully consider the particular rights, obligations and exceptions under the CCPA.

Key Takeaway: The Future Is Uncertain

The CCPA could become the most significant privacy law in the United States in terms of the rights offered to consumers and the       }
            else if (ResultFileManager::getTypeOf(id) == ResultFileManager::PARAMETER) {
                const ParameterResult *parameter = manager->getParameter(id);
                writer.recordParameter(parameter->getModuleName(), parameter->getName(), parameter->getValue(), parameter->getAttributes());
            }
            else if (ResultFileManager::getTypeOf(id) == ResultFileManager::STATISTICS) {
                const StatisticsResult *statistics = manager->getStatistics(id);


about.

just read on packers news that koren will not be prosicuted until after the 2006 season and this means that the nfl officials will not be able to punish him until after the season is over.... so i dunnno what to think?

nice...sign him...yeah, he's a charcter issue, but green bay is a relatively small and boring town...not a lot to do to get yourself in trouble...and packers haven't had a kick returner since desmond howard.

dude the town on mankato Minn where he got arrested is prob the biggest **** hole of a town ever and he still managed to ge in trouble there. he'd be more likely to get busted in a small town because the only thing to do is get hammered.

__________________
What do the vikings and marijuananjx9

as far as i'm concerned, DWI's and DUI's are far WORSE than anything Owens has ever done. Owens is scum in the locker room. Robinson attempted to murder someone by getting behind the wheel.

You just answered your own question.

Quote:

Originally Posted by Nitschke-Hawk

Anybody putting him in the same category as T.O. and such should stop. Those people don't have this type of problem.

--------------------------------------------------------------------
I hate Owens as much as most, but these two guys problems are completely different, the only category they belong in together is being wide recievers that have problems and get extra chances. T.O. isn't an alcoholic and isn't putting his life in danger as well as others. Robinson was already in rehab and even went back this summer to help prevent a relapse, well he had


an intelligent automatic power-off function terminates current when charging is complete. Don’t hesitate any more!

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How do you deal withvarious environment. Moreover, automatic memory function, reverse power protection and low voltage indication are all supported. A bargain for you!

Mini and portable, this MANKER E11 XP-L V5 7-Mode 800lm Cool White Flashlight has been widely accepted by people for daily lighting performance. With top-grade aluminum coating, this flashlight is too wear-resistant to break easily. Special treatment on surface makes this flashlight resistant to any potential damage. It features 7-mode design, allowing you to select any mode you need. Also, with excellent waterproof performance, it can be used under wet condition. Would like to buy one for climbing, camping, diving or other purposes? Come to have a try!

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are yet to be discovered. Making an OS lighter by
changing the implementation is likely to introduce unintended new
vulnerabilities.

The OSes you mention have relatively small user base and thus their security
models are relatively unproven. I note that all of the environments you
mention use Linux for the userland and thus you will have apps that also have
potential security risks.

Perhaps it would be better to re-frame your question in terms of the
requirements that you intend to address. For example for highest level of
security you could go with an OS like seL4 and rewrite everything to avoid
Linux system vulnerabilities. Probably not practical. And the rewrite is not
guaranteed to be bug free.

The most secure environments are carefully specified and architected for their
intended application. The more general purpose an environment the greater the
number ofFurrow-related contractions are inhibited but furrow-unrelated contractions are not affected in af mutant eggs of Xenopus laevis.
In embryos from af mutant females of Xenopus laevis, the cleavage furrows stayed on the surface and cytoplasmic divisions did not take place at all, while nuclear divisions continued (Kubota et al., 1991). To gain insights into the roles of the normal product of af on early development, contractile events which have been observed in the period from fertilization until first cleavage in wild-type eggs were examined in af mutant eggs. Activation waves, activation contraction, and surface contraction waves which were identical to those in wild-type eggs were observed in af eggs by time-lapse video recording. However, second polar body elimination was inhibited in af eggs, although a sign of the polar


and May of this year, more than 80 percent of people who have fled from Russia are Chechens. The fifth-largest group of asylum seekers in Germany currently hails from Russia, with around 2,770 refugees. Russia follows Syria, Afghanistan, Iran, and Iraq.

Other numbers can still be found on the website for the Federal Office for Migration and Refugees (BAMF). According to the site, just 850 people came from Russia in April, which would put it in ninth place.

Whatever the number, relatively few Chechens are ever granted asylum. Only around 6 percent of asylum seekers from the region have their applications approved. State Secretary in the Federal Interior Ministry Ole Schröder (CDU), wants things to stay that way. According to EU rules, asylum seekers have to file their application inothers. Another approach to address the innovation gap in natural product discovery is to utilize the intrinsic chemical reactivity of functional groups that are enriched in a target class of metabolites. Here, we report the development of a reactivity-based screening method to identify, isolate, dereplicate, and characterize novel natural products using a combination of bioinformatics and a simple chemical probe for modifying a reactive functional group (Figure [1](#fig1){ref-type="fig"}).

![Strategy for natural product discovery by bioinformatics-guided prioritization and nucleophilic 1,4-addition chemistry. (a) Reaction scheme for the thiol (DTT/DIPEA) labeling method with 1,4-addition sites indicated with yellow circles. (b) Work flow for the bioinformatics-based strain prioritization, subsequent DTT-labeling, and MS screening (reactivity-based screening). (1) Prediction of DHAA-containing thiopeptide biosynthetic gene clusters from 400 in-house sequenced genomes (all from the USDA ARS


been demonstrated that thiol nucleophiles participate in 1,4-addition into α,β-unsaturated carbonyl/imine DHAAs under mild conditions to yield covalent thioether adducts (Figure [1](#fig1){ref-type="fig"}a).^[@ref17]^ This reactivity has been exploited previously in the chemical modification of thiostrepton,^[@ref18]−[@ref20]^ the mapping of Ser/Thr modifications in proteins,^[@ref21]^ the design of solid-phase capture resins,^[@ref22]^ and the identification of lanthipeptides.^[@ref23]^ Thus, we sought to employ this well-established, reliable chemistry as part of a novel tandem bioinformatics/reactivity-based screening effort.

![Representative natural products bearing dehydrated amino acids (DHAAs). Structures of example molecules that contain DHAAs suitable for nucleophilic addition are shown. The sites of potential nucleophilic reactivity (*i.e.*, the DHAA alkenes, often in the form of an α,β-unsaturated carbonyl) are indicated with yellow circles. LAP, linear azol(in)e-containing peptide.](cb-2014-00324n_0003){#fig2}

Many classes of DHAA-bearing natural products are ribosomally produced, rendering them idealwith compound detection or analysis.

Bioinformatics-Guided Strain Prioritization {#sec2.3}
-------------------------------------------

Like lanthipeptides, thiopeptides are RiPPs, and the biosynthetic genes responsible for their production are often clustered, rendering them identifiable by sequence similarity searching. From the perspective of the present study, we sought to prioritize bacterial strains for subsequent screening based on the presence of biosynthetic genes capable of installing DHAAs (often misleadingly annotated as "lantibiotic dehydratases").^[@ref12]^ These genes, however, can be found in a variety of other natural product gene clusters and not exclusively in thiopeptide clusters. Therefore, we first identified clusters that encode for the YcaO cyclodehydratase protein that is necessary for the biosynthesis of all thiazole/oxazole-modified microcin natural products, of which thiopeptides can be broadly categorized. Strains containing a YcaO cyclodehydratase were analyzed further for the local co-occurrence of


the Cyclothiazomycin C Biosynthetic Gene Cluster {#sec2.6}
-------------------------------------------------------------------------

To provide additional evidence that the thiopeptide gene cluster from WC-3908 was responsible for the production of cyclothiazomycin C, conservation analysis was performed with the cyclothiazomycin A, B, and C (putative) gene clusters. The cyclothiazomycin A biosynthetic genes derived from *Streptomyces hygroscopicus* subsp. *jinggangensis* 5008, while the cyclothiazomycin B genes were from *Streptomyces mobaraensis*. A subset of the genes predicted for the production of cyclothiazomycin B^[@ref37]^ was conserved among the three clusters (Figure [5](#fig5){ref-type="fig"}b). All three clusters contain a short open reading frame, here designated *ctmA*, encoding the precursor peptide. *CtmD* encodes a "fused" TOMM cyclodehydratase (E1 ubiquitin-activating enzyme/MccB-like and YcaO domains), which implicates CtmD in the formation of thiazolines.^[@ref43],[@ref44]^*CtmB* encodes a flavin mononucleotide-dependent protein, putatively responsible for the dehydrogenation of thestars stand for the Shoshone, Paiute, Goshute and Ute tribes that lived in the area before the arrival of white settlers, and the blue background is inspired by the blue skies that help define Salt Lake City as a world-class destination for outdoor recreation.

“The shape of the mountain symbol is inspired by a crown,” Annsa wrote. “This is meant to reference the city’s status as the capital of Utah, and as the primary city in our region.”

(Courtesy of Amie Annsa) A proposed Salt Lake City flag by Amie Annsa.

Nickname: “Gull”

Daniel Jensen’s design uses red for the University of Utah and Salt Lake City’s sunsets, dark blue for Lake Bonneville, light blue for the Great Salt Lake, white for snow and salt, and gray for the shadows of Lake


programming language, one that
is widely used among developers working in that language.

  The "System Libraries" of an executable work include anything, other
than the work as a whole, that (a) is included in the normal form of
packaging a Major Component, but which is not part of that Major
Component, and (b) serves only to enable use of the work with that
Major Component, or to implement a Standard Interface for which an
implementation is available to the public in source code form.  A
"Major Component", in this context, means a major essential component
(kernel, window system, and so on) of the specific operating system
(if any) on which the executable work runs, or a compiler used to
produce the work, or an object code interpreter used to run it.

  The "Corresponding Source" forthe status
of the particular user or of the way in which the particular user
actually uses, or expects or is expected to use, the product.  A product
is a consumer product regardless of whether the product has substantial
commercial, industrial or non-consumer uses, unless such uses represent
the only significant mode of use of the product.

  "Installation Information" for a User Product means any methods,
procedures, authorization keys, or other information required to install
and execute modified versions of a covered work in that User Product from
a modified version of its Corresponding Source.  The information must
suffice to ensure that the continued functioning of the modified object
code is in no case prevented or interfered with solely because
modification has been made.

  If you convey an object code work under this section in,


In the following three paragraphs, a "patent license" is any express
agreement or commitment, however denominated, not to enforce a patent
(such as an express permission to practice a patent or covenant not to
sue for patent infringement).  To "grant" such a patent license to a
party means to make such an agreement or commitment not to enforce a
patent against the party.

  If you convey a covered work, knowingly relying on a patent license,
and the Corresponding Source of the work is not available for anyone
to copy, free of charge and under the terms of this License, through a
publicly available network server or other readily accessible means,
then you must either (1) cause the Corresponding Source to be so
available, or (2) arrange to deprive yourself of the benefit of the
patent license forOF MERCHANTABILITY AND FITNESS FOR A PARTICULAR
PURPOSE.  THE ENTIRE RISK AS TO THE QUALITY AND PERFORMANCE OF THE PROGRAM
IS WITH YOU.  SHOULD THE PROGRAM PROVE DEFECTIVE, YOU ASSUME THE COST OF
ALL NECESSARY SERVICING, REPAIR OR CORRECTION.

  16. Limitation of Liability.

  IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING
WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MODIFIES AND/OR CONVEYS
THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, INCLUDING ANY
GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES ARISING OUT OF THE
USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT NOT LIMITED TO LOSS OF
DATA OR DATA BEING RENDERED INACCURATE OR LOSSES SUSTAINED BY YOU OR THIRD
PARTIES OR A FAILURE OF THE PROGRAM TO OPERATE WITH ANY OTHER PROGRAMS),
EVEN IF SUCH


One of the gun control opponents says the bills on the table are an infringement on their second amendment rights.

"Guns are the only way we have of defending ourselves against someone who outweighs us, or catches us (off guard) and I believe we should have the right to defend our homes against intruders and anyone else who threaten to do us harm," said Ellis Thompson, a gun control opponent.

A Minnesota Senate committee is expected to analyze several gun control bill proposals on Thursday and Friday at the capitol.                  | ![Screenshot](https://github.com/SabakiHQ/theme-photorealistic/raw/master/screenshot.png)                           |
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| [Cartoon Theme](https://github.com/geovens/Sabaki-Theme#cartoon)


confinement of prochiral reactants (and transition states formed at the chiral active center) would provide an altogether new method of boosting the enantioselectivity of the anchored chiral catalyst. Initially, we anchored chiral single-site heterogeneous catalysts to nanopores covalently via a ligand attached to Pd(II) or Rh(I) centers. Later, we employed a more convenient and cheaper electrostatic method, relying in part on strong hydrogen bonding. This Account provides many examples of these processes, encompassing hydrogenations, oxidations, and aminations. Of particular note is the facile synthesis from methyl benzoylformate of methyl mandelate, which is a precursor in the synthesis of pemoline, a stimulant of the central nervous system; our procedure offers several viable methods for reducing ketocarboxylic acids. In addition to relying on earlier (synchrotron-based) in situ techniques for characterizingHunter Biden wasn’t qualified to be on Burisma’s board4.Lt. Col. Vindman and Jennifer Williams both agreed Hunter’s position at Burisma had the potential for the appearance of a conflict of interest3.Ambassador Taylor basically admitted Hunter Biden’s position at Burisma ‘raises questions’2.Marie Yovanovitch confirmed that there was concern in the Obama State Department about Hunter Biden’s conflict of interest at Burisma1.George Kent said there were legit concerns about Hunter Biden, and Burisma should be investigated

ARI MELBER

RIGHT SCOOP sets this clip with the followin: “This is pretty great. Ari Melber actually told the MSNBC panel and their audience that the Democrats did not prove their case that Trump committed obstruction of Congress, and everyone flipped out.” By “flipped out,” they mean Lefties responses to this commentary, which you should see


Great Budget Bag

I was in the market for a down sleeping bag that would keep me warm without wiping out my funds. Unfortunately all the nice, high quality bags are usually hundreds of dollars. Then I spotted this bag. It's been reviewed by backpacker magazine so after reading that I went ahead and got it (for about $110). It's 550 fill down so it's not AS lofty or thick feeling as some of my friends high end bags but it definitely gets the job done. I took it backpacking above Chilnualna Falls in Yosemite and was comfortable even when the temperature dipped slightly below 20F overnight.

Overall I would say this is a great bag if you want something that will keep you warm and is relatively cheap, but1. Field of the Invention
The present invention relates generally to an electro-photographic printer or copier, and, in particular, to an apparatus for exposing a photoconductive intermediate image carrier of the printer or copier with different gray scale levels using a light source.
2. Description of the Related Art
Electrographic printing or copying devices are known (as shown for example in European patent document EP 0 683 954 B1). Such a printing device contains a driven intermediate support, which may be a photo-conducting drum, on which charge images of images to be printed are generated. The charge images have toner applied to them, the toner is transferred to a print medium, such as paper, and the toner is fused onto the print medium. To accomplish this, the printing device contains the


Randomized treatment study of inosiplex versus combined inosiplex and intraventricular interferon-alpha in subacute sclerosing panencephalitis (SSPE): international multicenter study.
The efficacy of oral inosiplex alone (group A) versus combined treatment of inosiplex (Isoprinosine) and intraventricular interferon-alpha2b (Intron A) (group B) in patients with subacute sclerosing panencephalitis (SSPE) was compared. One hundred and twenty-one patients who met the diagnostic criteria for subacute sclerosing panencephalitis and presented at stage 2 or less were randomized into group A or B. Data were analyzable on 67 patients who met the inclusion criteria and adhered to the protocol. The inosiplex dosage was 100 mg/kg/day to a maximum of 3 g/day, taken orally in three divided doses for 6 months. Interferon-alpha2b started with 100,000 U/m2 and escalated to 1,000,000 U/m2 over 5 inpatient days anda university level SEO content writer to describe our services and including pages on "About" "How it Works" "Why we are different" and then specific content about our industry including compelling reasons to use our services. Ideally 300...

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Sunday, January 6, 2013

And Again

I'll give my rides so far this year one thing: consistency. As in, we have been consistently sucking ass with jumps.

I pretty much never jump more than once a week, and if I do, it's only twice a week. However, since Bobby's jumps have been more along the lines of ground poles and jumps so little they may as well be considered ground poles, I made Saturday another jumping ride. I set up a wide-ish 2'6" oxer and left the little 2' vertical up with no intention of going over it. Stupid little jump that hates my soul.

We started off with a really good canter to the right. Thanks again, George.

I've been working really hard mentally to judge Bobby's approach to jumps. Sometimes heSite-directed mutagenesis of conserved Thr407, Asp433 and Met464 residues in small subunit of Escherichia coli gamma-glutamyltranspeptidase.
Sequence comparison showed that residues Thr407, Asp433, and Met464 in the small subunit of Escherichia coli gamma-glutamyltranspeptidase (EcGGT) were conserved in the aligned enzymes. In this study, we further investigated the functional significance of these conserved residues by site-directed mutagenesis. The wild-type and mutant enzymes were overexpressed in the recombinant E. coli M15 cells and purified to near homogeneity by Ni2+-NTA resin. Except M464L, other mutants had shown no GGT activity under enzyme assay conditions and activity staining. Furthermore, mutations on these residues impaired the capability of autocatalytic processing of the enzyme. Based on these observations, it is concluded that these residues play an important role in the enzyme maturation.