figure. Without iron, this detector is about 1/10 the mass of a conventional detector.

[r]{}[0.6]{}

![image](4th-detector.eps){width="0.55\columnwidth"}

Tracking by cluster counting in a low-mass He-based drift chamber
-----------------------------------------------------------------

The gaseous central tracker is under study as a cluster-counting drift chamber modelled on the successful KLOE main tracking chamber [@Trk-Review; @pisa]. This drift chamber (CluCou) maintains very low multiple scattering due to a He-based gas and aluminum wires in the tracking volume and utilizes carbon fiber end plates. Forward tracks (beyond $\cos \theta \approx 0.7$) which penetrate the wire support frame and electronics pass through only about 15-20% $X_{0}$ of material. The low mass of the tracker directly improves momentum resolution in the multiple scattering dominated region below 10 GeV/c. The He gas has a low drift velocity which allows a new cluster counting techniquecalorimeter modules. The dual readout of these crystals is essential: over one-half of all hadrons interact in the so-called [em]{} section, depositing widely fluctuating fractions of [em]{} and hadronic energy losses.

The fiber calorimeter shows promise of excellent energy resolution on hadrons and jets, as seen in Figure \[Fig:Eres-3\] for 200 GeV $\pi^-$: (a) the distribution of the scintillator ($S$) signal shows the raw resolution that a typical scintillating sampling calorimeter would achieve; (b) shows the leakage-dominated energy distribution using only the scintillating $(S)$ and [Ĉerenkov ]{}$(C)$ signals for each event; and, (c) shows the energy distribution with leakage fluctuations suppressed using the known beam energy (=200 GeV) to make a better estimate of the [em]{} fraction each event. The actual energy resolution of a fiber dual-readout calorimeter lies


remains larger than 0.5 T$\cdot$m out to $\cos \theta = 0.975$, allowing both good momentum resolution and low-momentum acceptance over almost all of $4\pi$ [@franco-mu-val].

For isolated tracks, the dual readout calorimeter independently provides a unique identification of muons relative to pions with a background track rejection of $10^4$, or better, through its separate measurements of ionization and radiative energy losses.

=6.0cm

The detector’s magnetic field is confined essentially to a cylinder with negligible fringe fields, without the use of iron flux return. This scheme offers flexibility in controlling the fields along the beam axis. The twist compensation solenoid just outside the wall of coils is shown in the above figure, along with the beam line elements close to the IP. This iron-free configuration [@Mik] allows us to mount all beamM. Tyndel, Y. Unno, C. Yuanbo, O. Qun. J. Brau, J. Haba, B. Zhou 15 April 2007.

ILC Calorimetry R&D Review, DESY ILC Workshop, 31 May - 4 June 2007, W. Lohmann (Chair).

ILC Vertex Chamber R&D Review, to be held at the ILC Workshop at Fermilab, October 2007.

4th Concept Detector Outline Document is available at the WWS-OC website http://physics.uoregon.edu/ lc/wwstudy/concepts/.

”Improving Spatial Resolution and Particle Identification”, G.F. Tassielli, F. Grancagnolo, S. Spagnolo, 10th Pisa Meeting on Advanced Detectors, 21-27 May 2006.

”Hadron and Jet Detection with a Dual-Readout Calorimeter”, N. Akchurin, [*et al.*]{}, [*Nucl. Instr. Meths.*]{} [**A 537**]{} (2005) 537-561.

”Measurement of the Contributions of Neutrons to Hadron Calorimeter Signals", N. Akchurin, et al., submitted to NIM.

”Dual-Readout Calorimetry with Lead Tungstate Crystals”, N. Akchurin, et al., submitted to NIM.

”A Few Comments on the


Status of Detectors for ILC”, Alexander Mikhailichenko, CLNS 06/1951, 15 Jan 2006.

”The Muon System of the 4th Concept Detector”, F.Grancagnolo, ILC Workshop - ECFA and GLD Joint Meeting, Valencia, Spain, Nov. 5-13, 2006.

”Electron Detection with a Dual-Readout Calorimeter”, N. Akchurin, [*et al.*]{}, [*Nucl. Instr. Meths.*]{} [**A 536**]{} (2005) 29-51.

”Muon Detection with a Dual-Readout Calorimeter”, N. Akchurin, [*et al.*]{}, [*Nucl. Instr. Meths.*]{} [**A 533**]{} (2004) 305-321.

Acosta, D., [*et al.*]{}, [*NIM*]{}, [**A302**]{} (1991) 36.

[^1]: This work has been supported by the US Department of Energy and by INFN, Italy.

[^2]: The [[dream ]{}]{}collaboration has recently succeeded in dual-readout of a single BGO crystal and will publish these results shortly. Separation in the more difficult PWO crystal[@dream-PWO] has also been accomplished .
electron microscope](EJD-12-574-g001){#F1}

RESULTS {#sec1-3}
=======

Cells cultured on hAM were identified in all samples prepared using either formaldehyde or glutaraldehyde, with or without sputter-coated gold. However, it was easier to recognize the cells' bodies and boards as well as the hAM surface topography on the samples prepared using formaldehyde fixative \[[Figure 2](#F2){ref-type="fig"}\]. Two undesirable features were observed in SEM images. The first was the presence of tears (ruptures) in some samples. The tears were observed in the cell layer as well as in the membrane \[[Figure 3](#F3){ref-type="fig"}\]. This feature was observed in both types of samples prepared using either glutaraldehyde or formaldehyde. The second undesirable finding was the presence of small white spots in some images \[[Figure 4](#F4){ref-type="fig"}\]. This finding was restricted to samples prepared using formaldehyde only. Finally, images from


(a) monitoring the cell voltage and current and calculating the resistance of the cell from the monitored voltage and current, PA1 (b) monitoring alumina additions to the cell, monitoring other additions to the cell bath and monitoring operational changes including anode movements, tapping, anode setting and beam raising, PA1 (c) continuously calculating the energy absorbed by the process from thermodynamic energy requirements associated with the cell reaction and the events identified in item (b) above, PA1 (d) calculating the heat available for dissipation in the cell from the cell voltage and current and from the continuously calculated process energy requirement determined in item (c) above, PA1 (e) calculating from the calculated heat available for dissipation in (d) and from a selected target power dissipation, the integral of theis one, a strong one." Simple but yet powerful. "As a community we are joined as El Paso strong," said Gloria Marquez. "This isn't going to go away tomorrow or the following month."A mural that shows unity, support and love for one another during a time of mourning."The artist actually said he would finish and he stayed all night to do it," said Pat Lira, a teacher in El Paso. "It's just showing that pride, and letting everybody know that we are united." Because when people think of El Paso, even though this Borderland community is 22 people less fewer -- they are stronger than they were the day before. "We are resolute in our desire to heal and persevere and we are resolute in our resilience and


points investigated. SSTS was also associated with greater patient ease of use (weighted mean difference [WMD]: 0.13; 95% confidence interval [CI]: -0.02-0.28) and a higher patient satisfaction score (WMD: 0.31; 95% CI: 0.05-0.57; p = .019) compared with PCTS. In terms of tolerability, all-cause withdrawals from treatment were reported to be less likely with SSTS (risk ratio: 0.65; 95% CI: 0.42-1.02). No significant differences were observed between SSTS and PCTS in terms of safety and adverse events. In the absence of direct head-to-head data, the combination of promising phase III trial results compared to IV morphine PCA, a SLR comparison against other opioid treatments, and the results of this exploratory analysis present a strong rationale in support of SSTS as a key option for management of post-operative pain.organization plays an imperative role in the incremental strategy development if it is harmonized with the environmental changes. Incompetent organizational culture may act as a barrier for a firm to keep their strategic directions in line with the environmental changes (Johnson et al., 2005). According to Pearce & Robinson 2009, the entity of today's global firms is that organizational culture should be acquainted with cultural diversity. Managing the relationship between strategy and culture in the firm is significant for the successful implementation of the strategy.

Organizational politics:

The Political observation of strategy development is that strategies develop as a result of processes of haggling and negotiation among the influential stakeholders of the firm. Political action is often perceived as an inevitable part of the strategy development process in an organization


follow strategy or does strategy follow structure?

Organizations seek new strategies for the reason that they offer new opportunities and potential advantages. Before implementing the strategy, a variety of factors needs to be considered because it involves change and risk. The link between structure and strategy is an important aspect to be considered before implementing the strategy. Structure of an organization is a vital factor since the change in corporate strategy might require some sort of change in the manner a firm is structured and in the type of proficiency required in specific positions of the firm (Wheelen & Hunger, 2008). According to Thomson & Martin 2008, although structures are designed primarily and changed later to fit the intended strategies of an organization, the daily activities and behaviors ofI examine this claim using three figures of merit: chemistry/Earth science, rainfall records, and flood records.

In chemistry, Henry’s Law states, in aqueous solution, as temperature increases, dissolved gases are driven from the solution. Regarding CO2, as ocean temperature increases, more CO2 is driven into the atmosphere. Temperature controls CO2, not the reverse. In the past 600 million years of Earth history, CO2 is now near its minimum; it’s been lost to limestone and other calcareous sediments. Temperatures, while fluctuating, have been relatively stable with no “tipping points.”

Flood records: The most severe Mississippi River/Louisiana flood occurred in spring 1927. Read the USGS’ “Floods of April-June 1953 in Louisiana and Adjacent States;” it rains and floods a lot in Louisiana, especially in spring.

Europeans have drawn flood watermarks on buildings and


half of all Donald Trump supporters as a “basket of deplorables.” In her mind, Trump’s troops include racists, sexists, homophobes, xenophobes and Islamaphobes, to name a few.

Heard of the Western “A Fist Full of Dollars”? How about a movie titled “A Basket of Deplorables,” or “Deplorable Me.” Hillary’s comments about deplorables is despicable.Hitler is on you @GOP. You’re carrying this monster to term. https://t.co/zwrU3EkxqQ — Mike Monteiro (@monteiro) July 4, 2016

Whether they support Trump or not there isn’t a single Jew on Earth who saw that Star of David and thought “that’s just a sherriff’ star.” — OhNoSheTwitnt (@OhNoSheTwitnt) July 4, 2016

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Remember when Hitler made six million Jewish sheriffs? Oh wait. He didn’t? He killed them instead. — (((Harry Enten))) (@ForecasterEnten) July 4, 2016

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*Trump starts drooling on himself* “I was just saying Hillary is a big star like Omar Sharif” *farts* — Ryan K Lindsay (@ryanklindsay) July 4, 2016

If this is true then why did the Trump campaign delete the image and change the star to a circle? https://t.co/4RmDi2FnPd — Sarah Burris (@SarahBurris) July 4, 2016

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57% of hate crimes are


underwent curative surgery, 5- and 10-year adjusted survival rates were 57.7% and 44.3%, respectively, with a median survival of 96 months. Postoperative hospital mortality was 6.8%:4.9% for R-0 resected patients, 9% for R-1 and R-2 resected patients, and 13.4% for those with palliative procedures. Multivariate analysis using the Cox model identified age older than 65 years, prior total gastrectomy, an increasing number of positive lymph nodes, a high pathologic N classification, male sex, a high pT classification, and low preoperative hemoglobin level as detrimental factors with an independent influence on survival. Radical lymphadenectomy in this 10-year Austrian study yielded survival rates similar to those in Japanese investigations without sacrificing low postoperative mortality. In particular, the relatively high overall survival rates seemed to reaffirm the value of radical lymphoriginally associated with the Elk, Reindeer or Ox.

The name is also invoked in songs telling of the origins of parts of other creatures including the cat's tail, and the raven's neck, body, legs, and guts, and one of its eyes. One song tells of the snake's creation from the saliva of a sleeping Hiisi, which was eaten by Syöjätär - it burned and she coughed it out - once dried out Hiisi gave it life.  (Tempo and Hiisi both appear in some forms of this creation text) The Aspen tree was also said to have come from Hiisi.

The Hornet (or wasp), closely associated with Hiisi (or Tempo) is a key element in the mythic creation of steel from iron - its sting - mistaken for honey by


the main one the same socket and everything else. And ZeroMQ seems to don't like this (programm aborted with a ZeroMQ error as soon as the process is forked).
I was looking for a module like Proc::Spawn that let me to share the STDOUT channel between the two process. Do you have any suggestion? Do you have any better way to accomplish this?

A:

Thank you for your help, but I've found a solution that fits perfectly to my problem using threads:
use threads;

my $loading_threads = threads->create(\&loading_animation, $process_name);
$loading_threads->detach();

Putting this just before the while I didn't have any problem.

Districts of Samoa

Samoa is made up of eleven itūmālō (political districts). These are the traditional eleven districts that were established well before European arrival. Each district has its own constitutional foundation (faavae) based on the traditional order of title precedence found in each district's faalupega (traditional salutations).

The capital village of each district administers and coordinates the affairs of the district and confers each districts' paramount title, amongst other responsibilities.

Examples of District Governance
Atua has it's capital at Lufilufi. The paramount pāpā title and ruler of Atua is the Tui Atua. The orator group which confers this title is the Faleono (House of Six) senior orators of Lufilufi.

The two paramount matai - called Tama a Aiga - are Tupua Tamasese, which is conferred by the Aiga Sa


MF led to an enhanced bioelectrochemical activity of Shewanella, and no significant promotion in mediator secretion was found. The improvement in the electricity production of MFCs under MF was mainly attributed to the enhanced bioelectrochemical activity, possibly through the oxidative stress mechanism. An accelerated cell growth under MF might also contribute to the enhanced substrate degradation and power generation.   Kavli Institute for Particle Astrophysics and Cosmology, Department of Physics and SLAC National Accelerator Laboratory, Stanford University, USA.\
    E-mail: mdimauro@slac.stanford.edu
author:
- 'Mattia Di Mauro, on behalf of the Fermi-LAT Collaboration'
bibliography:
- 'ws-pro-sample.bib'
title: 'The origin of the Fermi-LAT $\gamma$-ray background'
---

Introduction
============

The $\gamma$-ray sky has been observed since 1972 by the OSO-3 satellite . This experiment provided the first $\gamma$-ray sky map with 621 events detected above 50 MeV and it first revealed the existence of an isotropic emission. The presence of this isotropic component, called Isotropic Diffuse $\gamma$-Ray Background (IGRB), then has been measured by SAS-2 and the EGRET satellites. Recently the [*Fermi*]{}-LAT has released a new measurement of the IGRB spectrum from 100 MeV to 820 GeV at Galactic latitude ($b$) $|b|>20^{\circ}$ . The LAT


Q:

Concerning the use of relative pronouns

The relative pronoun quem in the following seems to function in a way that I wouldn't normally associate with relative pronouns:

Et accipiens puerum, statuit eum in medio eorum: quem cum complexus esset, ait illis:...

What strikes me as odd is that the dependent clause seems to be set off by both quem and cum.
The point becomes clearer when the phrase "quem cum complexus esset" is compared with the Greek for which it is a translation: καὶ ἐναγκαλισάμενος αὐτὸ. In the Greek, instead of a relative pronoun, a personal pronoun is used; i.e. αὐτὸ instead of quem, and the clause is set of by the participle without any interference by a relative pronoun.
Because of this, I'm led to think that quem, in this particular case,Q:

Reflection in Windows Universal Apps

I need to use the GetProperties method so I can test whether any properties in a particular class has a specified custom attribute. However it doesn't appear as though Windows Universal Apps supports this:
obj.GetType().GetProperties()

Raises the error:
'System.Type' does not contain a definition for 'GetProperties' and no extension method 'GetProperties' accepting a first argument of type 'System.Type' could be found (are you missing a using directive or an assembly reference?)

What do I need to reference in order to make use of the full reflection library?
Thanks in advance.

A:

Add this to your using statements:
using System.Reflection;

Then you can use obj.GetType().GetRuntimeProperties() method. This method returns all properties defined on the specified type, including inherited, non-public, instance, and static properties. Keep in mind that this behavior is slightly different than the


cnt; i++) {
		struct dso *dso = dsos[i];

		unlink(dso->name);
		dso__put(dso);
	}

	free(dsos);
}

static int set_fd_limit(int n)
{
	struct rlimit rlim;

	if (getrlimit(RLIMIT_NOFILE, &rlim))
		return -1;

	pr_debug("file limit %ld, new %d\n", (long) rlim.rlim_cur, n);

	rlim.rlim_cur = n;
	return setrlimit(RLIMIT_NOFILE, &rlim);
}

int test__dso_data_cache(int subtest __maybe_unused)
{
	struct machine machine;
	long nr_end, nr = open_files_cnt();
	int dso_cnt, limit, i, fd;

	/* Rest the internal dso open counter limit. */
	reset_fd_limit();

	memset(&machine, 0, sizeof(machine));

	/* set as system limit */
	limit = nr * 4;
	TEST_ASSERT_VAL("failed to set file limit", !set_fd_limit(limit));

	/* and this is now our dso open FDs limit */
	dso_cnt = limit / 2;
	TEST_ASSERT_VAL("failed to create dsos\n",
		!dsos__create(dso_cnt, TEST_FILE_SIZE));

	for (i = 0; i < (dso_cnt - 1); i++) {
		struct dso *dso = dsos[i];

		/*
		 * Open dsos via dso__data_fd(), it opens the data
		 * file and keep it open (unless open file limit).
		 */
		fd = dso__data_fd(dso, &machine);
		TEST_ASSERT_VAL("failed to get fd", fd > 0);

		if (i % 2) {
			#defineWe're taking a whole new approach.

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WATCH: Joy Behar Says Jesus Would Have Made Cake For Gay Weddings

In 2012, Jack Phillips of Masterpiece Cakeshop in Colorado declined to design a wedding cake for gay couple, Charles Craig and David Mullins.

As these things tend to go, “Craig and Mullins filed a civil rights complaint and won, first before an administrative court judge, then before the state Civil Rights Commission, and finally before the Colorado Court of Appeals,” according to USA


he approved of their sins; he ate with them because, like the physically sick, they were spiritually sick, and they needed a physician. People like Faris often use the “but Jesus hung out with sinners” argument. However, the text states that Christ met with sinners because he knew how spiritually ill they were — the clear implication being that he disapproved of their ways.

On to Behar, the prophetess. She claimed that Jesus would have baked the cake. She offered no reasoning as to why she believes this — although one can deduce her thought process based on her history. Behar likely holds to the progressive trope that Jesus was all about love, and because of that, he would do anything for anyone.

However, Christ himself condemned many sins. Heproblems in a more direct manner. The TGF mechanism will be studied by measuring single nephron glomerular filtration rate or glomerular pressure during perfusion from a late proximal tubular site or from an early distal tubular site. Studies evaluating the role of intrarenally generated angiotensin II will utilize peritubular capillary infusions or in vitro superfusion of angiotenin I. Using both in vivo and in vitro approaches, we will investigate further a) the relative contributions of the TGF mechanism and the myogenic mechanism to overall autoregulatory responses b) the regulatory influence of enhanced intrarenal formation of angiotensin II on afferent and efferent arteriolar resistances, the glomerular filtration coefficient and the sensitivity of the TGF mechanism, and c) the specific localization of the resistance adjustments during autoregulation. Further attention will


services to be performed by the plaintiff fall squarely within the category of "ancillary" or "incidental" work. The task of sanding and grinding rust spots and then painting the water tank at a height of between thirty-five and fifty feet obviously calls for a specially equipped crew. It is easily distinguished from the type of routine painting of *219 hydrants and pipes, painting over graffiti, and other maintenance carried on by the defendant's own employees. The job of painting the tank was undertaken only occasionally  prior to the accident in 1965, the tank was painted in 1960 and 1952  and the work was, as far as the record shows, consistently awarded to independent contractors. Thus, it could not be found that the plaintiff's work constituted athe same condition as they were or appeared to be in at the time *223 of the letting.[6] Reasoning that "the status of the person visited, landowner or lessee, should not affect the visitor's right to personal safety or the landowner's obligation reasonably to maintain premises in his control," we invoked the Mounsey rationale to impose a duty of reasonable care on the landlord with respect to all lawful visitors. Id. at 82. We thus recognized that the legal relationship between landlord and tenant was not a rational basis for distinguishing the duty owed by the landlord to his tenant's visitors from that owed to other lawful visitors.[7] Similarly, the employee of an independent contractor engaged to work on the property of a property owner is a "lawful


that such rule is the appropriate one to be followed consistently with the views expressed in Mounsey and its progeny.
For the reasons stated, the judgment of the Superior Court is affirmed.
So ordered.
QUIRICO, J. (with whom Hennessey, C.J., and Wilkins, J., join, concurring in the result).
This action was tried by the parties and submitted to the jury on the plaintiff's claim that he was injured by reason of a hidden or concealed defect on the defendant's premises, of which defect the defendant was aware or should have been aware through the exercise of reasonable care. The jury returned a substantial verdict for the plaintiff. The defendant appealed, contending that there was insufficient evidence to support the verdict. The Appeals Court agreed, reversed the judgment and vacated the verdict. Onyet, we see what actually happened: we see the barbarism with a modern face, barbarism with modern technologies, enabling the regimes, and their supporters of course, to commit or support crimes much bigger, much greater, in some cases more terrible than in any of the past. So, that view, which kind of cyclical view of history, you find it in writers like Machiavelli, in ancient Greek and Roman historians; some [?] apart from Machiavelli nearly modern period, then it nearly dies out more or less: that's what nearly all human beings believed until a few hundred years ago. And I think that in many cases--I'm not opposed to modernists, but sometimes I think I'm a pre-modernist--I think the ancient writers, the ancient thinkers, religious or not, were in


Russ Roberts: comfort-- John Gray: comforts of daily existence, and so on. Russ Roberts: I don't have to wash my clothes. I don't have to haul water from the-- John Gray: Yes. They are nearly all spin-offs from the new technologies, which in turn are spin-offs from the growth of knowledge. So, that's progress. Russ Roberts: But also--but you have to be fair: They are also spin-offs of the economic and political systems that are put in place-- John Gray: Yes, well that's where I become-- Russ Roberts: in places that don't have those, aren't doing so well-- John Gray: That's where I become more skeptical than you, and I think you should be, too-- Russ Roberts: [?]-- John Gray: You have stronger-than-my belief in the benign consequencesthey called barbarism--which preceded it and which still existed in parts of the Roman Empire or edges of the Roman Empire--it would be a very different experience, not a much better experience but a collapse. So, if one isn't sort of blindsided by looking back only 200 or 300 years, and if one doesn't think that what has been achieved on a more global level has to last and endure, then you can see that this could be a major setback. And of course, the work in the 20th century--the setback which followed the First World War and the Bolshevik Revolution in Russia was colossal. They didn't get back-- Russ Roberts: or Weimar-- John Gray: anything. Sorry? Russ Roberts: The Weimar Republic. And the post- -- John Gray:


everything is permitted. John Gray: Mm. Russ Roberts: And the--I think a lot of secular humanists, and the New Atheists, especially, believe that a morality can be fashioned without God. You can also argue--I'm not going to--I'm a religious person but obviously you can argue that religious morality has many flaws. That's not what I'm talking about. John Gray: Well, all kinds of hidden [?] concepts[?]-- Russ Roberts: Has many flaws. You can argue-- John Gray: What has many flaws? Russ Roberts: Religious morality. John Gray: Yes. Yes. Yes.

58:24 Russ Roberts: So, obviously, there's much to talk about there. But I think most people--most people who reject religion believe, earnestly, that a morality can be fashioned without a law-giver. Without the divine, a creator. And you are extremelyI'm trying to be a little cynical-- John Gray: Yeah. Russ Roberts: Yeah. Some would say enhanced. But have shaped atheist philosophies in ways that atheists are unaware of-- John Gray: Absolutely-- Russ Roberts: and it's a very--it's a somewhat condescending argument, but it may be true, nevertheless. I think the deeper point you are making right now, which is profound, is that it's very hard to be free of your time--and you think you are. There's a wonderful story in the Talmud where, through a dream, a rabbi encounters a wicked man from the past. I forget who it is. It's not important. But he says--and he finds out--he's actually a pretty decent guy. In the dream. And he says, 'Well, how can you be so wicked


mentioned this before: I get listeners who tell me, 'You're smart. Why are you a religious person?' And-- John Gray: Yeah-- Russ Roberts: the idea that in the past, of course, people were religious only because they didn't understand everything. And now that we understand everything, of course religion will wither and die away. But is, as you point out-- John Gray: I think that's a form of credulity. I think religions are useful now. Antidotes to credulity. Russ Roberts: Well, it's going to emerge and evolve in interesting ways, or thoughts on these things.

1:10:59 Russ Roberts: I want to close with two questions. First question is: You argue that much of human history--not 'much'--all of human history is cyclical. That the progress-- John Gray: Well, there arewe want, we just scrap it and get rid of it, you could say, 'Well, Judaism hasn't worked for me, or Christianity: I'm giving it up. Instead I'm becoming a drug taker.' 'Or, I'm becoming a follower of Ayn Rand.' I think that's a kind of way of life which will--you turn your life into a series of not-very-interesting short stories rather than being a deep human life. Which can only come from committing yourself rather deeply in daily practice to certain things, which might be religion or it might be learning an art or a craft of some kind, or it might be some human relationships, or even relationships with animals that you've cultivated. But it has to be deep and abiding and continuing. It can't just


Transaortic Aortic Valve Implantation in 100 Patients: Follow-up to 3 Years.
Transaortic aortic valve implantation (TAo-AVI) through the ascending aorta is a novel technique and is used as an alternative in patients with poor femoral access. Although early results have been promising, no midterm data have been published yet. To determine whether this approach is an acceptable treatment option, we analyzed the first 100 cases performed at our institution with a follow-up to 3 years. Between July 2011 and January 2015, a total of 100 patients with high-risk or inoperable aortic valve stenosis were treated with TAo-AVI. Preoperative patient data were collected and analyzed retrospectively. All surviving patients were seen for clinical and echocardiographic examination for follow-up. Median follow-up was 15 months. Device success was accomplished in 94 patientson Son Doong cave by Mark Jenkins in the January 2011 issue of National Geographic Magazine. But first, enjoy some of the beautiful pictures illustrating the natural beauty of Son Doong. A half-mile block of 40-story buildings could fit inside this lit stretch of Hang Son Doong, which may be the world's biggest subterranean passage. (Photo Credit: © Carsten Peter/National Geographic)

Like a castle on a knoll, a rock formation shines beneath a skylight in Hang Son Doong. A storm had just filled the pool, signaling that exploring season was coming to an end.(Photo Credit: © Carsten Peter/National Geographic) Navigating an algae-skinned maze, expedition organizers Deb and Howard Limbert lead the way across a sculpted cavescape in Hang Son Doong. Ribs form as calcite-rich water overflows pools. (Photo Credit:


massaging in the middle. I know all dogs are different and recover differently but Im wondering has anyone got their dog back out on the trail for overnight backpacking after this type of surgery? If so, in what what kind of time frame post surgery (again I know all dogs heal different and may require more or less time). I would like to take him on the annual Thanksgiving trip covering 30-40 miles over 4 days but I am wondering when it would be safe to start with some small hikes this summer. If it helps at all, we would be doing most of our hiking on the Appalachian Trail on the east coast.

Work him up to it slowly, and if he doesn't act sore, then he istake any damage at all. Sure, it’s cool to be able to survive being impaled and then regenerating, except for the part where it would really fucking hurt to get impaled. Sure, if you’re the Swamp Thing and you’re made of moss, it probably doesn’t hurt much, if at all, but if you’re Wolverine, it still hurts like hell. Obviously Wolvie has a bonkers pain threshold, but there’s got to be times where he wouldn’t mind switching powers with Kitty Pride or Colossus.

I’ve read a few LitRPG books, where characters are put in a position where they’re essentially playing a game. Sometimes they literally are, through a Matrix quality VR setup, and I don’t really care for those because as far as I’m concerned, the stakes are super


Spatial environmental heterogeneity affects plant growth and thermal performance on a green roof.
Green roofs provide ecosystem services, including stormwater retention and reductions in heat transfer through the roof. Microclimates, as well as designed features of green roofs, such as substrate and vegetation, affect the magnitude of these services. Many green roofs are partially shaded by surrounding buildings, but the effects of this within-roof spatial environmental heterogeneity on thermal performance and other ecosystem services have not been examined. We quantified the effects of spatial heterogeneity in solar radiation, substrate depth and other variables affected by these drivers on vegetation and ecosystem services in an extensive green roof. Spatial heterogeneity in substrate depth and insolation were correlated with differential growth, survival and flowering in two focal plant species. These effectsneed to change my requirements.txt file on my projects on each new release.
Simple git repository
Create a new repository to store my *.py files and include them as a django app such as 'common_deps'. Then add it to my PYTHON_PATH
I need some advices, I haven't chosen yet. I'm just telling myself that git submodules seems to be a bas idea.
Tell me guys.

A:

I will definitely go with the second option you listed - packaging your app. If you follow steps in the Packaging your app part of official Django tutorial, you'll get tar.gz file which will allow you to include your app in any project you want by simply installing (e.g. with pip) to the virtual env connected with the project or globally


relative to the predictions of the isobaric cooling-flow model. However, as predicted by the cooling-flow model, a temperature drop in the center of many clusters is observed, typically reaching one third of the peak temperature [e.g., @2003Peterson; @2005Vik]. Clusters presenting such a temperature drop in their cores are referred to as cool-core (CC) clusters [@2001Molendi].

Using a very large, high-resolution cosmological N-body simulation (Millennium-XXL), @2012Angulo showed that cosmological conclusions based on galaxy cluster surveys depend critically on the selection biases, which include the wavelength used for identification of clusters of galaxies. @2011PlanckXMMvalid [@2013PlanckXMMvalid] presented the first observational evidence of different morphological properties in X-ray vs. SZ selected samples: SZ selected clusters have a less peaked density distribution and are less X-ray luminous at a given mass than X-ray selectedvalues. $n_{\rm e}$ is the electron density, given by Equation \[eq:nenp\], and $T_{\rm 3D}$ is the deprojected 3D temperature, given by Equation \[eq:tprof\].

![image](conc_csb4.eps){width="33.00000%"} ![image](conc_cusp.eps){width="33.00000%"} ![image](conc_n0.eps){width="33.00000%"}

![image](csb4_cusp.eps){width="33.00000%"} ![image](csb4_n0.eps){width="33.00000%"} ![image](cusp_n0.eps){width="33.00000%"}

Results
=======

With the cluster gas density and emission measure profiles, we are able to compute the cuspiness of the gas density profile, concentration, and central gas density for the X-ray and [*Planck*]{} ESZ cluster samples. The uncertainties on the metrics for each cluster were computed using 100 Monte Carlo realizations of the density profile, including also a Gaussian distribution for $r_{500}$ ($r_{500} \pm
\sigma_{r_{500}}$). The top left panel of Figure \[fig:hist\_metrics\] presents the distribution of concentration parameters in the 0.15–1.0 $r_{500}$ range for both cluster samples. We used a Kolmogorov–Smirnov (K-S) test for the SZ and X-ray samples to evaluate the probability that the


Q:

Getting syntax error, unexpected end-of-input

I keep getting a syntax error, unexpected end-of-input, despite checking the code, and even after removing the code and running it the problem seems to not be solved.here is the code :
class BookingsController < ApplicationController

before_filter :authenticate_user!

def new
    @booking = Booking.new
end

def create
    @booking = current_user.booking.create(booking_params)
    if @booking.save
        flash[:alert] = "You have now booked a date"
        redirect_to root_path
    else
        flash[:alert] = "Error:booking did not save"
        redirect_to root_path
        render 'new'
    end
end

def show
    @booking =on your Drupal site. It basically inserts a hidden form field to Drupal (or other) forms with a field name like 'homepage' (you can set it to whatever you want). End users don't see the field, so they don't fill it out. But spam bots (usually using prewritten scripts) do see the field (usually), and add something to it. The Honeypot module detects this and blocks the form submission if there's something in the field. It does this without disabling cache.
Note: The Honeypot provides two methods. The timestamp method does disable caching, so use the Honeypot method.


my weakened muscles back to work and craniosacral therapy restored my body’s natural rhythms.

I was fortunate: I had the will, the family support, the research skills and the financial means to pursue unconventional healing methods. Fighting the system is much harder for those who don’t have the money, the knowledge of alternative therapies or the emotional strength to keep up the lonely struggle for recovery. Too often, such people live with pain, disability and despair.

Doctors must understand what illness means in the lives of their patients. They must use their positions, their authority and their words wisely. They have the power to heal, but they also have the potential to destroy hope and, along with it, the chance to recover.

In what appears to be a perfect union betweenAuldearn's because it was bigger than Auldearn's other hats. But there is a certain condition in which one's new hat will be bigger than one's old: it is if one happens to suffer from Paget's disease.'

If Gott relished the odd turn his narrative was taking he gave no sign. His voice flowed on without emphasis. 'Lord Auldearn was gravely ill. But why was there such passion behind a technical diagnostic discussion between Nave and Dr Biddle – a conversation overheard by Mr Appleby and myself in the hall? I can remember what they said. "Clearly the localized form," Nave said, "Leontiasis Ossium." And Dr Biddle replied "Leontiasis fiddlestick...simple generalized Paget's." And over that Nave was passionately angry. Why? Well, I need not and cannot be technical. Put it


see what I mean at once. The first thing I casually mentioned to Mr Appleby when speaking of Bunney was the fact of a certain resemblance to himself. And the same thing, Mr Appleby tells me; misled Rauth, the steward, this morning. The spies, then, guessing that the document had been transferred to Mr Appleby's possession, made one last throw. But the person they thought was Mr Appleby going to Bunney's room to investigate the business of the cylinder was actually Bunney himself. And when they found that their plan had miscarried they very adroitly stole the "curious message" cylinder, thus removing suspicion of the attack from themselves and transferring it to the murderer. With the realization of this simple sequence of events Nave's last defence breaks down.'

AAmpersand Papers
While Appleby is strolling along a Cornish beach, he narrowly escapes being struck by a body falling down a cliff. The body is that of Dr Sutch, an archivist, and he has fallen from the North Tower of Treskinnick Castle, home of Lord Ampersand. Two possible motivations present themselves to Appleby – the Ampersand gold, treasure from an Armada galleon; and the Ampersand papers, valuable family documents that have associations with Wordsworth and Shelley.
---|---
---
  | Appleby and Honeybath
Every English mansion has a locked room, and Grinton Hall is no exception – the library has hidden doors and passages...and a corpse. But when the corpse goes missing, Sir John Appleby and Charles Honeybath have an even more


humour, irony and devastating suspense.
---|---
---
  | A Night of Errors
A gruelling night of shrouded motives and confused identities develops when the last of the Dromios is found murdered, with both of his hands burnt off. He was one of triplets, whose brothers had died in a fire forty years previously. Inspector Appleby wrenches the facts from a melodrama in which the final solution is written in fire.
---|---
---
  | Old Hall, New Hall
The forbears of Sir John Jory, of New Hall, would seem to have committed several foul acts, including tomb-robbery and murder. Old Hall, the family's former residence, is now a University. Biographer Colin Clout, engaged to write an accountwhich enables fast universal qubit control.'
author:
- Hendrik Bluhm
- Sandra Foletti
- Diana Mahalu
- Vladimir Umansky
- Amir Yacoby
date: '11/27/10'
title: Enhancing the Coherence of a Spin Qubit by Operating it as a Feedback Loop Controlling its Nuclear Spin Bath
---

[^1]

[^2]

Spins in semiconductors are attractive qubits because of their long coherence times [@Ladd2005; @Tyryshkin2003; @Childress2006], their electrical control and readout [@Petta2005], and their potential for scalability [@Taylor2005]. Few-electron quantum dot devices have been used successfully in recent years to demonstrate universal control of electron spin qubits as well as single shot readout [@Elzerman2005; @Press2008; @Barthel2009; @Foletti2009]. However, interaction of the qubit spin(s) with nearby nuclear spins is a significant source of decoherence in several systems [@Petta2005; @Childress2006; @Koppens2006; @Fischer2008; @Tyryshkin2003]. It is therefore very attractive to prepare the spin environment of the electron


known to the outside world.

Electron-nuclear feedback mechanisms were previously observed in resonance locking experiments under microwave [@Vink2009] and optical irradiation [@Xu2009; @Latta2009; @Greilich2007]. In Refs. [@Vink2009; @Latta2009], a narrowing of the hyperfine field was inferred from the observed bidirectional polarization keeping the system on resonance, but not experimentally verified. In Ref. [@Xu2009], narrowing was detected spectroscopically, and Ref. [@Greilich2007] studied an ensemble of optically controlled quantum dots. Here, we directly measure the narrowed distribution of the hyperfine field and the dephasing time, $T_2^*$, of a single, electrically controlled qubit. $T_2^*$ is enhanced by nearly an order of magnitude. In contrast to previous experiments, where the feedback mechanism is intrinsic to the polarization dynamics [@Danon2009; @Rudner2007], we have intentionally designed it by manipulating the qubit.

The spin qubit studied inBody dysmorphic disorder in patients undergoing septorhinoplasty surgery: should we be performing routine screening?
Body dysmorphic disorder (BDD) is defined as having a preoccupation with a perceived flaw in one's appearance, which appears slight to others and significantly interferes with a person's functioning. When undetected in septorhinoplasty patients, it will often lead to poor outcomes. We performed a prospective cohort study to determine the prevalence of BDD in our patients and whether surgical correction could be considered. We recruited 34 patients being considered for septorhinoplasty in a tertiary referral rhinology clinic and a control group of 50 from the otology clinic giving a total of 84. Participants completed the Body Dysmorphic Disorder Questionnaire (BDDQ), the sino-nasal outcome test-23 (SNOT-23) and underwent nasal inspiratory peak flow (NIPF). Those found to


don't understand is why these languages don't have a var keyword to use on declaration, to make a distinction between a declaration and an assignment. This doesn't make the language any less dynamically typed, and I see no drawbacks.
What is the advantage of not having to explicitly define a variable?

A:

As a user rather (than designer) of Python there are three reasons I'm happy with this decisions:
Chiefly, it reads better. Of course I have to consciously decide to introduce a new variable when writing, but code is read far more often than it is written. A lot of code is simple in the sense that control flow and nesting has no influence on the meaning and existence of variables. When I read
it = Snark()
message = "A letter,since (at least in Python) a variable is either local for the entire function or not at all, you can't have tricky code that uses a local variable in one branch and a global one in another. You see a name being assigned to? You instantly know it was always local from the beginning. Well, unless the code is broken in a very special way (and will throw the dreaded UnboundLocalError at run time, when entering those cases).


R-Calif., yanked every last committee assignment from King, granting an effective green light to an emerging crop of Republicans aiming to primary King in the 2020 election.

The Democratic Party now faces its own question. Freshman Rep. Ilhan Omar, D-Minn., whom the Left has deemed a rising star in the progressive wing of the party, said the quiet part out loud, yet again.

Responding to a report of McCarthy promising "action" against Rep. Rashida Tlaib, D-Mich., and Omar for their anti-Semitic dog whistling and support of boycott, divestment, and sanctions policies punishing Israel, Omar commented on Twitter, "It's all about the Benjamins baby."

Hackneyed Puff Daddy reference aside, Omar's insinuation, that McCarthy is sensitive about anti-Semitism only because that's where the money is, echoes old anti-Semitic stereotypes and tropes about aGood morning Hank, it's Tuesday
I can't find my Norton Anthology of Poetry
I don't mean *the* Norton Anthology of Poetry
which can be purchased from any bookstore
I mean *my* Norton Anthology of Poetry
or, more specifically, my friend Chip's Norton Anthology of Poetry
that I borrowed from him in 11th grade and then eventually stole.
The 3rd edition of the Norton Anthology of Poetry is a deeply flawed book
for one thing, it contains almost no poems from the last 40 years
on account of having been published 35 years ago
but it is *my* deeply flawed book, or at the very least, Chip's
and I can't find it.
One of the central facts of my life is that
no matter how many times I reorganize my home library
in any given moment I will. not. be able
to find the


The following essay is a work in progress, produced for an anthology of essays on animation and its relations to live action comedy. I see it as a chance to explore cartoons, long a passion of mine, but so far, not a topic I've written about. It also gave me a chance to return to the field of comedy studies, where I began my career. For more of my work on this topic, see What Made Pistachio Nuts?: Early Sound Comedy and the Vaudeville Asesthetic, Classical Hollywood Comedy, and the essay on Lupe Velez in The Wow Climax. It also extends the exploration of the relations between high and popular art which runs as a theme through the essays in The Wow Climax, but especially those dealing withother spaces, creating different kinds of works for different kinds of audiences. They enjoyed their own marginality and often made fun of the pretensions and obscurtism of more exalted forms of artistic expression.

We might use the term, "vulgar," in a descriptive sense to describe the relatively low cultural status granted their work at the time it was being produced; we might deploy the term, "vulgar," to refer to certain intentionally distasteful aspects of their representation of the body and sexuality, their deployment of everyday materials including advertising as the inspiration for their own artistic production, though in that sense, they prefigure where art has gone in the postmodern period. Can we rescue "vulgar" by redefinining it in terms of transgressions committed both against the institutional practices of mainstream


repulsion blocks the current. The (donor) quantum dot is characterized by an odd ground state (red) and an even excited state (blue) so that $E_{ES}=E_{GS}+\Delta$. In the cases 1-3, the upper part of the stability diagram is generated by the processes **a** and **b** of Figure 2. Differently from standard Coulomb blockade diagrams of a two level system, the ES does not participate to tunneling because of its opposite valley index parity. In the lower part of the stability diagram, the selection of even (blue) electrons for tunneling generates a shifted triangle (processes **c** and **d**). In the case 1, the transition from ES to GS is forbidden so the current is allowed also for $eV_{sd}<\Delta$. In cases 2 and 3 one electron is present in the quantumdetermined by a control gate. Valley parity flip is prevented by the ideality of the sample. Donor quantum dots proved to have a high valley splitting (1.5 meV to tens of meV) in Silicon nanostructures. Irrespectively from the spin, the electrons flowing through the GS and the ES have a $o$ and $e$ valley parity respectively. The control gate switches the donor quantum dot from a 0 to a 1 electron state, in order to align alternatively the GS and the ES with the Fermi energy of the source. The source is supposed to contain spin and valley unpolarized electrons. The device is terminated by two drains $D_1$ and $D_2$ through two arms, each containing a donor quantum dot, with $E_s > E_{d1},E_{d2}$. Each donor quantum dot at


M. Fanciulli: Phys. Rev. B **80** (2009) 165331 M. Friesen, P. Rugheimer, D. E. Savage, M. G. Lagally, D. W. van der Weide, R. Joynt, and M. A. Eriksson, Phys. Rev. **B 67**, 121301(R) (2003) G. P. Lansbergen, G. C. Tettamanzi, J. Verduijn, N. Collaert, S. Biesemans, M. Blaauboer and S. Rogge: Nano Letters **10** (2010) 455 Y. Hada and M. Eto, Phys. Rev. **B 68**, 155322 (2003) S. Goswami, K. A. Slinker, M. Friesen, L. M. McGuire, J. L. Truitt, C. Tahan, L. J. Klein, J. O. Chu, P. M. Mooney, D. W. Van Dreweide, R. Joynt, S. N. Coppersmith and M. A. Eriksson: Nat. Phys. **3**, 41 (2006) G. Frucci, L. di Gaspare, F. Evangelisti, E Giovine, A. Notarigiacomo, V. Piazza, and F. Beltram, Phys. Rev.opted to ask writers who write picture books/board books.

Where would we meet?

In-person groups allow for more socialization. You can bring along a book you’ve found, break bread, and just get to hang with other writers.

Online groups, which allow you to critique at your own convenience, give you the opportunity to really study a submission before you comment. They are easier to fit into a busy schedule and don’t require geographical closeness to the other members.

I’m an online type of gal. I like to read a manuscript several times before I comment, and I like to get feedback in writing. It makes revising much easier for me.

How big?

Just how many members should you invite? This is an important question because it dictates how much time you devote to critiques.

I


scheme, we start an efficient and fast evaporation process as a result of the sub-second thermalization rate of the magnetically trapped ensemble.'
address: '$^1$Department of Physics of Complex Systems, Weizmann Institute of Science, Rehovot 76100, Israel'
author:
- 'Ido Almog, Jonathan Coslovsky, Gil Loewenthal, Arnaud Courvoisier and Nir Davidson'
bibliography:
- 'bibliography.bib'
title: High phase space density loading of a falling magnetic trap
---

*Introduction -* Quantum degenerate gases [@Anderson1995; @pethick_smith_2008; @Truscott2001] have proven to be essential tools in the exploration of fields such as condensed-matter physics [@Bloch2005], quantum simulation [@Bloch2012], study of phase transitions [@Greiner2002] or topological properties of matter [@Goldman2016]. Reaching quantum degeneracy in dilute gases requires numerous cooling stages [@Phillips1997], and their joint integration in a single experimental apparatus can become cumbersome. A prominent example is the combination of Raman sideband cooling (RSBC) [@Kerman2000] and conventional evaporation in a magneticthe jejunum and ileum of knockout and control mice, and the proximal colon of control mice (but not knockout mice) respond to the mucosal addition of 50 nM STa with decreases in absorption; and (5) mucosal guanylin caused similar decreases in proximal colon absorption in control and guanylin-deficient mice. These findings suggest that guanylin deficiency causes basal Cl- secretion and reduced responsiveness to STa in mouse proximal colon. The effectiveness of guanylin in this segment suggests a difference in the intestinal secretory actions of STa and guanylin.


over like this. I don’t think Patti’s comments were meant to offend but I’m a matchmaker for gay men and monogamy is a big topic with every single one of my clients. The truth is, if a gay man wants monogamy it’s available to him. In fact, most of my current clients want a monogamous relationship. A few have indicated they would consider an open relationship after a year or so, if it were important to their partner and provided there was good communication. But even the gay relationship success stories I’ve shared are all monogamous.

If a gay man wants a boy toy or a one-night stand, that too is available to him and he doesn’t have to pay a matchmaker to find it. You’ve heard of Grindr,as a result, the vortices, having thus been destabilized, move out of the cavity. Vortex instability actually increases with increasing *Re*, causing the effects of the base cavity to diminish.Fig. 12Size of flow separation region (*x)* for the thick blunt trailing-edge airfoils with and without the base cavity at various Reynolds numbers

In Fig. [13](#Fig13){ref-type="fig"}, the horizontal velocity component along the vertical section is given for the thick blunt trailing-edge airfoil with and without the base cavity. The distance from the airfoil trailing edge is equal to 40% of the chord length, and the Reynolds number and attack angle are equal to 2150° and 5°, respectively.Fig. 13Horizontal velocity component for a section located at 0.40% of the chord length form the trailing edge (angle of attack = 5° and *Re* = 2151)

Using the base cavity has


wrongly associate their opposition with a man who stabbed three men, killing two, on a Portland commuter train last month.

Across the street and two sets of police barricades, Marjorie Stamberg, a New York City teacher, held up a sign that read "drive fascists out of NYC."

“Two people were murdered in Portland a few weeks ago by their people," she said. "If they tell you it's about free speech, they're liars. They're killers. They're haters.”

Here’s a live feed from the New York march:

And another from Lansing, Michigan:

And a feed from Chicago:

Twitter user @bbusa617 tweeted a map showing all the planned protests:

@ACTforAmerica Saturday June 10Th 2017

**MARCH AGAINST SHARIA**

All Across Our Nation pic.twitter.com/COs0RrBSVG — ????brooks brown???????????? (@bbusa617) June 9, 2017

In Roseville, Calif. more than 100 counter-protesters were planning to show up,Mindful is a mission-driven non-profit. We’re dedicated to inspiring, guiding, and connecting anyone who wants to explore mindfulness—to enjoy better health, more caring relationships, and a compassionate society.

How often have you rushed out the door and into your day without even thinking about how you’d like things to go? Before you know it, something or someone has rubbed you the wrong way, and you’ve reacted automatically with frustration, impatience, or rage—in other words, you’ve found yourself acting in a way you never intended.

Intention refers to the underlying motivation for everything we think, say, or do. From the brain’s perspective, when we act in unintended ways, there’s a disconnect between the faster, unconscious impulses of the lower brain centers and the slower, conscious, wiser abilities of the higher centers


Memphis psychiatrist Richard Farmer was taken into custody of the U.S. Marshals as his sixty years of practice culminated in disgrace.

MEMPHIS: Dr. Richard G. Farmer, age 82, was indicted by a federal grand jury on April 11, 2019 on charges that he “issued prescriptions for controlled substances… at his medical clinic in Memphis, Tennessee, outside the usual scope of professional practice and without a legitimate medical purpose, and often in exchange for sexual favors or companionship.”

[Farmer] issued prescriptions for controlled substances… outside the usual scope of professional practice and without a legitimate medical purpose, and often in exchange for sexual favors or companionship.

The indictment states that Farmer often prescribed Oxycodone—a Schedule II drug that is highly addictive and has a high potential for abuse—along with Alprazolam (Xanax), awho has ever player COD: Black Ops 2's zombie mode; four players are dumped into a map filled with hostile creatures, given a task to accomplish and are awarded cash for each kill, with which they can then buy weapons and equipment. This time, however, they're fighting an invasion of feral alien quadrupeds, rather than a zombie horde.

Even without the undead, there's fun to be had. In Extinction, the idea is to use a drill to dig through the roots of alien plants while alien pooches attack from all sides.

Players can deploy ammo, guard turrets, explosives and there are even a couple of items in their environments – such as a firetrap – that they can unlock, provided they have the cash. It recreates the frenetic shooter action


Enosis Neon Trust

Enosis Neon Trust (, Enosi Neon Trust, "Youth Union Trust") was a Cypriot football club based in Nicosia. It was a founding member of the Cyprus Football Association. The disbanding of the Pancyprian Football Organization (, "Pagkypria Organosi Podosfairou (POP)") in 1924 led to the creation of two new clubs: Trust AC and Panergatikos. Trust took their name from the English word trust.

The first Cypriot Championship and first Cypriot Cup were organized in 1934/35 and Trust won both competitions, thus becoming double winners for the first time in Cypriot football history. In the cup final of 1934,/35 Trust beat APOEL 1-0 in the replay final. The first leg was 0-0.

They were again cup winners in 1935/36, when they beat LTSK 4-1, but were beaten in theIf God makes it happen, great! I’m there to learn and have a good time with 600 other people who know exactly what it’s like to argue with people who exist only in your head. Who don’t think it’s weird that someone is on the floor in the corner scribbling like a madman.

I also made the choice that first year to not make any appointments. I think that was the best choice I ever made. No pressure. At least of the pitching kind. This year, I’m doing appointments. But the thought doesn’t scare me because I took the time to just observe and enjoy myself.

So if you see someone looking like a sponge, it’s just me, enjoying myself and soaking up everything I can. (And if I have


cellular transcription factors \[[@B60]-[@B63]\]. However, cells that lack or have a low level of HIV-1 expression are also present and contribute to viral persistence. It is still controversial whether or not true latency occurs in infected cells from the monocyte-macrophage lineage. For this reason, but also to avoid confusion, the word latency will be used in the following sections, not *stricto sensu*as previously defined, but in a larger sense which includes true latency and low ongoing replication. Contrary to the CD4+ T cells, in which the mechanisms of the establishment and the maintenance of true latency have been well described \[[@B64]\], our knowledge of the molecular mechanisms underlying latency in the monocyte-macrophage lineage is poor. Like in CD4+ T cells, two types of latency occur in cells fromHIV-1 transcription and make them attractive for devising new drugs to control AIDS \[[@B97],[@B98]\]

HIV-1 transcription is also modulated by proteins of the Sp1 family which differ in the nature of the Sp protein bound to the LTR and of the cell type. Indeed, Sp1 and Sp3 are both expressed in microglial cells, unlike CD4+ T-cells, which express only Sp1. In microglial cells, although Sp1 acts as an activator of HIV-1 transcription, the Sp3 protein represses the HIV-1 promoter activity \[[@B99]\]. Some factors, like IL-6, or hydroxyurea could synergistically reactivate HIV-1 replication in latently promonocytic cells by increasing the ratio of Sp1/Sp3 \[[@B100]\]. Serpin B2, a serine protease inhibitor induced in activated monocytes and macrophages during inflammation is also able to increase the Sp1/Sp3 ratio by inhibiting Rb-degradation, and


involved in the activation of transcription. This strategy should be able to by-pass drug-resistance which arises with viral proteins. Therefore, ways to synthetize drugs which interfere with HIV-1 replication in monocyte-macrophage should be devised \[[@B175]\]. Several transcriptional inhibitors already characterized such as C-terminally truncated STAT5, Staf 50, Prothymosin α and thioredoxin reductase \[[@B176]-[@B179]\] could be used for controlling viral expression in the human macrophages. Inhibition of the NFAT5-LTR interaction by using small interfering RNA is also promising since it suppresses HIV-1 replication in primary macrophages and therefore progression of AIDS \[[@B180]\]. The discovery that only macrophages are able to repress HIV-1 transcription and replication in response to Il10 need further investigation since we could specifically control HIV-1 expression in these cells \[[@B129],[@B181]\]. The demonstration that treatment of HIV-1be designed with properties that allow them to penetrate tissue-sanctuary sites such as the brain \[[@B166]\].

Strategies based on virus reactivation from latent reservoirs
-------------------------------------------------------------

Recently, a new and original strategy has been proposed to eradicate the virus from infected patients. The main idea is to facilitate the reactivation of viruses from latent reservoirs, which are then destroyed by HAART (figure [3](#F3){ref-type="fig"}). Many factors have been involved in reactivation including physiological stimuli, chemical compounds like phorbol esters, histone deacetylase inhibitors, p-TEFb activators, and some activating antibodies (antiCD3). Many eradication protocols passed preclinical studies \[[@B2]\] but to date all failed in clinical trials. Some protocols failed due to the potential toxicity of treatments based on non specific cell activation such as IL2 \[[@B184]\]. The recent discovery that an alternatively spliced form of


Calculate k(x(s)).
-73381272608*s**2
Let c(j) = -112*j + 300. Let l(i) = 16*i - 41. Let h(t) = -6*c(t) - 44*l(t). Let n(d) = d. Give h(n(m)).
-32*m + 4
Let a(k) = -k**2 - 5*k + 5. Let b(v) = 2*v - 8. Let p(n) = -2*n + 7. Let u(t) = 5*b(t) + 6*p(t). Let i(d) = 2*a(d) - 5*u(d). Let j(f) = 5*f. Give i(j(w)).
-50*w**2
Let b(t) = -313*t**2 + 625*t**2 - 319*t**2. Let s(l) = 7*l. What is b(s(n))?
-343*n**2
Let a(i) = 21*i**2 + 19 - 14 - 5. Let c(d) = 2*d**2. What is c(a(w))?
882*w**4
Suppose -7*d + 1523 = -2572. Let w(t) = -585*t + t**2 + d*t. Let y(z) = -48*z. Determine y(w(l)).
-48*l**2
Let j(o) = -3*o**2. Let b(v) = -v**2 - 6*v + 27. Let w be b(-7).quantify pulsatile fluid velocities, flow rate, and flow reversal. Four-dimensional flow imaging in the dissected aorta revealed pockets of reverse flow and vortices primarily in the false lumen. The dissected aorta exhibited significantly greater flow reversal in the proximal-to-mid dissection as compared to normal (21.1 ± 3.8 vs. 1.98 ± 0.4%, p < 0.001). Pulsatility induced unsteady vortices and a pumping motion of the distal intimal flap corresponding to flow reversal. Summed true and false lumen flow rates in dissected models (4.0 ± 2.0 L/min) equaled normal flow rates (3.8 ± 0.1 L/min, p > 0.05), validated against external flow measurement. Pulsatile aortic hemodynamics in the presence of an anatomic, elastic dissection differed significantly from those of both steady flow through a dissection and pulsatile flow through a


At Opensignal we have always prided ourselves on our ability to measure what the consumer experiences on mobile networks . We measure the real-world speeds consumers see on their smartphones, rather than the highly optimized connections typically reported. We track how often real users have access to 4G signals in the places they frequent, rather than using complicated models to predict coverage. We run our latency tests not to specialty test nodes, but to the servers from which consumers seek their content. Opensignal's philosophy has always been that the only metrics that matter are the ones that measure the true consumer experience. The rest are just ephemera.

Real-world speed and real-world availability are very useful for gauging the power and reach of an operator's 4G services, but speed and  Elevation = waypoint.ElementOrNull(gpx + "ele"),
                      Name      = waypoint.ElementOrNull(gpx + "name"),
                      Dt        = waypoint.ElementOrNull(gpx + "cmt")
                 };

A:

Use what you feel the most comfortable with, as long as it gets the job done.  I use both methods depending on what I need to do to with


that information in the website
are up to date, accurate and correct, the readers/ users are requested to make an
independent enquiry with the Company before relying upon the same. Nothing on the
website should be misconstrued as advertising, marketing, booking, selling or an offer
for sale or invitation to purchase a unit in any project by the Company. The Company
is not responsible for the consequences of any action taken by the viewer relying on
such material/information on this website without independently verifying with the
Company.

The Alembic group is one of the top builders in Vadodara and Bengaluru and we have been changing the face of real estate in Gujarat and Karnataka. The real estate business in India has been slowly on the rise and we are glad to be a part of thecalls them, Rep. Katherine Clark, D-Mass., has campaigned for more effective tactics for dealing with online harassment. Furthermore, organizations such as Crash Override Network assist with the creation of safe spaces for those who feel they've been attacked online.

But there's still work to be done, Fox says. Because whether the industry is aware or not, "the adolescent teenage male gamer," is a thing of the past.

At 31 percent, women age 18 or older represent a significantly greater portion of the game-playing population than the 17 percent that concerns men age 18 or younger, according to the Entertainment Software Association.

Fox says QuiVr's response to Belamire's claim is one step in the right direction, and that women should not be disengaged from gaming just because there's some negative aspects.

"I really


Throughout history, Arcane has slaughtered the champions of the Red and the Green, and only Alec has escaped death – but for how much longer?

FRANKENSTEIN, AGENT OF S.H.A.D.E. #0

Written by MATT KINDT

Art and cover by ALBERTO PONTICELLI and WAYNE FAUCHER

On sale SEPTEMBER 12 • 32 pg, FC, $2.99 US • RATED T

• Frankenstein meets his maker…literally!

• Learn how Frankenstein was recruited by S.H.A.D.E.

• What does the future hold for S.H.A.D.E.?

I, VAMPIRE #0

Written by JOSHUA HALE FIALKOV

Art by ANDREA SORRENTINO

Cover by CLAYTON CRAIN

On sale SEPTEMBER 26 • 32 pg, FC, $2.99 US • RATED T+

• Witness how Andrew Bennett became a vampire!

• Who was the monster that attacked him? How did his powers develop? And why is he the only vampire able to control his terrible hunger for blood?

DEMONpaper did not suppress melatonin or cause participants to feel groggy the next day.

This study shows that the bright blue light from displays at night is impacting our sleep. If you stay up late reading a bright iPad until just before bedtime, your sleep will be negatively affected, and your body will expect to stay up later the next night (as much as 90 minutes later). You may have trouble winding down, feeling alert when you should be getting tired.

This level of melatonin suppression is quite large. Melatonin is known as the sleep hormone, and has many functions in the body related to sleep. It is also a strong anti-inflammatory known to suppress cancer cell growth.

Because the circadian shift of using an iPad at night is very large,


dont think you expiring it in the backed is going to work as you would like.
For the fun of it
TimeSpan t = TimeSpan.FromSeconds(Int32.MaxValue);
Console.WriteLine(t.Days);

results in a very ugly 24855 days or 68 years.

Dripsey

Dripsey () is a village in County Cork on the R618 regional road around 20 km west of Cork City. It is situated on a tributary of the River Lee, the Dripsey River. It is in the Catholic parish of Inniscarra. The Dripsey area hosts a Cork County Council water treatment plant, the Cork offices of the Environmental Protection Agency, and an award-winning garden center. The village has two pubs (The Lee Valley Inn and The Weigh Inn), and one shop - which also doubles as the post office. Dripsey has one primary school and one pre-school.

Name and formation
Dripsey's name is derived from the Irish name Druipseach, which means muddy river. The village is made up of the Lower Dripsey, Dripsey Cross and Model Village areas. 'Model Village' is


ONE OWNER, CLEAN VEHICLE HISTORY, Local Trade!, All Wheel Drive, 2015 Nissan Rogue SV, 4D Sport Utility powered by a 2.5L I4 cylinder engine mated to a CVT transmission with Xtronic. Finished in Super Black with Charcoal Cloth Seat Trim, ABS brakes, Alloy wheels, Front dual zone A/C, Fully automatic headlights, Power driver seat and Remote keyless entry.This vehicle has been fully serviced by our service department with a 150-point inspection and is offered with a 6-Month/6,000-Mile limited comprehensive warranty. This is just part of what it takes to become Kelly Certified. All of our vehicles come with our 3-Day/150-Mile Money Back Guarantee and 30-Day/1,000-Mile Trade Out Policy. It is Live Market Priced by scanning over 40,000 websites to assure you of the best value for your money.We'll show you our 150 point inspection in writing, and signed by one of our factory certified technicians. 4) We've been in the Lehigh Valley since 1967, we'll be here tomorrow. 5) Live Market Pricing: To assure you of the best value for your dollar. ***Kelly Nissan in Easton - Your New Nissan and Used Car Dealer Serving Easton, Nazareth, Allentown, Emmaus, Phillipsburg, Bethlehem, and the Pocono's***

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im 2 months pregnant. 2 weeks ago, around the time i usually get my period i started having brown blood for about 2 days. now 2 weeks later, im spotting light red blood. its only when i wipe myself and im having mild cramps. also about a week ago i started getting back pain. my neck head back legs and feet hurt. im really sore. my mom says im fine but im not sure.

Thanks for your Reply!

2 Replies |Watch This Discussion | Report This| Share this:adviceim 2 months pregnant. 2 weeks ago, around the time i usually get my period i started having brown blood for about 2 days. now 2 weeks later, im spotting light red blood. its only when i wipe myself and im having mildhis fatherly warmth. In fact, my annoying behavior encouraged him to start carrying his signature cane. As time passed, he began caning me and my brothers for the slightest infraction.

Thankfully, my father had a different attitude when it came to the females in our family. I never heard him shout at his mother, his sisters, my mother, or my sisters. I never saw him strike a woman. He reserved all the harsh treatment for his sons.

I remember one particular time, during the Russian occupation of Afghanistan, when he had been away for longer than usual. I was desperate for his attention. He was sitting on the floor quietly studying intricate military maps. I watched him as he carefully laid his map flat on the floor, his earnest face


kind of word." "It's got a masculine sound." "It's like shotgun and ash can and tow truck." "Cornhole." "Everything's been sanitized now and cleaned up." "First with these fucking Christians." "You just start with them." "You know." "I'm so, you know." "That's just one, wait a minute now." "Yeah, you know." "Let's not leave out these" "PC campus liberal assholes." "I mean they're just as fucking bad from a different direction." "But everything's different." "Everything's been polished up now." "It's anal intercourse." "Anal rape." "Bullshit." "Cornhole." "Now I'm a big fan of the prime time crime shows." "I like all of them pretty much." "You know." "I like "Law  Order"" "and all the spin-offs of that." "I like "CSl"" "and all of those spin-offs." "Yeah." "Because they're"Trying to get it just right." "First draft." "Second draft." "Third revision." "Whole new ending." "Finally, he'd turn it into a book proposal and have a reason to live." "That wouldn't work." "I think about stuff like that." "It's interesting to me." "Like I said." "Certain things are interesting." "Suicide's interesting." "Life is filled with interesting things." "That's why I could never commit suicide." "I'm having too much fun keeping an eye on you folks." "Watching what you do." "Human behavior." "That's what I like." "Humans do some really interesting things." "Like besides killing ourselves, we also kill each other." "Murder." "And we're the only ones who do that, by the way." "We're the only species on earth that deliberately kills members of our own species for personal


to be a parent, you got to be full of shit at least half the time." "Look at it this way, they have it both ways." "If the kid turns out to be a loser." "They had nothing to do with that." "But boy if he is a winner, got a scholarship or something like that, man, they are the first ones out there raising their hands trying to take a little credit." "It's a nice state of mind if you can talk yourself in to believing it." "But these are the kind of things I think about when I'm sitting home alone during an electrical storm waiting for the parole officer to give me a call." "And these ideas." "These ideas come floating into my head." "Justand the suburbs burn uncontrollably." "And thousands of identical homes have identical fires with identical smoke killing all the identical soccer moms and their identical kids named Jason and Jennifer." "And now." "Now the fire spreads to the farmlands and the farmlands burn intensely of 425 degrees creating millions of baked potatoes." "And as the farmlands burn." "As the farmlands burn." "Thousands of barns and farmhouses begin to explode from all hidden methamphetamine labs." "And the meth chemicals run downhill into the rivers and streams where wild animals drink the water and get completely geeked on speed." "So bears and wolves amped up on crank start roaming the countryside looking for people to eat even though they're not really hungry." "Then the fire spreads to the forest." "And


if it's an emergency or not." "He can't decide this." "He doesn't know." "Wow." "Oh it's hard work." "You know." "He can't decide because Dick Cheney is in prison." "So instead he takes a nap." "He takes a nap." "He puts his empty, fucking brainless head down on the little pillow his mother gave him at Christmas time and he takes a fucking nap." "So the fire moves to Philadelphia but it's a weekend and Philadelphia's closed on the weekends." "So the fire moves to New York City and the people of New York tell the fire to go fuck itself." ""Go fuck yourself."" "And it does." "And it does." "So instead it burns down Long Island and Connecticut killing all the rich white assholes and completely destroyingand all the dead people from the past begin falling through." "Babe Ruth." "Groucho Marx." "Davy Crockett, Tiny Tim," "Porky Pig, Hitler," "Janis Joplin, Alan Ludden my Uncle Dave, your Uncle Dave." "Everybody's Uncle Dave." "An endless stream of dead Uncle Dave's falling through the crack." "And all the dead Uncle Dave's gather around a heavenly kitchen table." "They light up cigarettes and they begin to talk." "They talk about how they never got a break." "How their parents didn't love them." "And their children were ungrateful." "They talk about how the government screwed them out of money and they just missed out on a big job." "They say the Jews own everything, and the blacks get special treatment." "And all the hatred and bitterness drips out of


Hill popped to second baseman Marco Scutaro.

He finished the eighth by winning an eight-pitch at-bat against Miguel Montero, who was the first Arizona hitter to get a three-ball count. Petit got out of the eighth inning with a full-count fastball that Montero grounded to first baseman Brandon Belt for the 24th out.

Petit opened the ninth inning by striking out Micah Owings on three curveballs. He threw just two pitches to Gerardo Parra, getting him to ground out to second.

And then it was Chavez, the respected old pro, called on to pinch-hit. With the count 2-2, Petit threw Chavez a slider that just missed low.

Had plate umpire Phil Cuzzi given Petit the call, no one would have said a word.

But with another full count, Petit threw Chavez an 89-mphof $2.3 billion over the past three years. That’s a lot of money!

Of course, losing money is fashionable in Silicon Valley, where investor subsidies are king and startups that bleed cash to acquire users reassure themselves that they’ll “make it up later in volume.” Profitability is also no longer a necessary precondition for a technology company to go public. Google (now Alphabet) and Facebook were profitable when they went public, but Twitter wasn’t, nor was Spotify, Blue Apron, Snapchat parent Snap, Box, Dropbox, Etsy, Roku, Square, Shopify, Twilio, and plenty of others.

Why does this matter? Well, a company that only loses money is not a very good business. Meal-kit company Blue Apron was valued at $3 billion by private investors who believed it could redefine the way America


have supported both the show, and the people involved in the show over these past four years. Thank you, everyone!

I will continue to be reachable via email and the contact link near the top of the site. Many times we have worked to connect developers and community members together and I do want that to continue. Please feel free to contact me anytime at me@ericmcclintock.com, all of the other addresses you have used in the past will continue to work as well.

The technical bits:

The FSBreak website and podcasts will continue to live on and be made available. We may switch servers but either way it will live on.

The Youtube, Facebook Page, etc will continue to stay up, and I'll try my best to stay connected to them.

The emailaddresses will continue to work just fine.

The voicemail line will continue to accept calls, but won't be monitored.

Eric's Skype account has never been a reliable way to get in touch, please email me!

Over the next few weeks, I'm going to be releasing all of the video episodes as separate RSS feeds for easy download. I have had this on my list for (literally) a year, but haven't had the time to do it.


There may be a light at the end of the tunnel for Britney Spears’ conservatorship. A source tells Us Weekly exclusively that the pop princess’ father, Jamie Spears, is looking into ending the court-approved order.

“Jamie is actively consulting with Britney’s medical team to determine if the conservatorship of Britney as the person should finally come to an end,” the insider says. “It’s just a question of timing as she is about to begin the tour, so the thinking is to do it at the conclusion.”

Britney, 36, is scheduled to kick off her Piece of Me tour in Washington, D.C., on July 12. She will travel across North America and Europe before the trek concludes in England on September 1.

The Grammy winner has been under the guidance of theconservatorship since 2008, after she was hospitalized for psychiatric evaluation in the wake of a highly publicized breakdown and divorce from Kevin Federline, with whom she shares sons Preston, 12, and Jayden, 11. The arrangement states that due to an undisclosed mental illness and past substance abuse, Britney cannot make personal or financial decisions without the approval of her father and lawyer Andrew Wallet.

“If anyone knew the real Britney, they would know that she would rather be remembered for being the great mother she is rather than the artist she is,” her ex-boyfriend David Lucado told The New York Times in May 2016. “And if anyone could see her interactions with her kids, they would know that there is no need for a conservatorship over Britney’s personal life.”

In


---
abstract: 'We report complex plasma experiments, assisted by numerical simulations, providing an alternative qualitative link between the macroscopic response of polycrystalline solid matter to small shearing forces and the possible underlying microscopic processes. In the stationary creep regime we have determined the exponents of the shear rate dependence of the shear stress and defect density, being $\alpha = 1.15 \pm 0.1$ and $\beta = 2.4 \pm 0.4$, respectively. We show that the formation and rapid glide motion of dislocation pairs in the lattice are dominant processes.'
author:
- Peter Hartmann
- 'Anikó Zs. Kovács'
- 'Angela M. Douglass'
- 'Jorge C. Reyes'
- 'Lorin S. Matthews'
- 'Truell W. Hyde'
title: Slow plastic creep of 2D dusty plasma solids
---

The direct in situ observation of dynamical processes in bulk condensed matter is not yet available with atomic resolution intemperatures. The shear stress curves in fig. \[fig:MD\](a) asymptotically join to a universal power-law function with a Norton exponent of $\alpha \approx 1/0.6 \approx 1.7$ at high shear rates. The effect of temperature is most dominant at low shear rates, where the system hardens with decreasing temperature, while reaching Norton exponents up to $\alpha \approx 1/0.12 \approx 8$ at the lowest investigated temperature. The defect fraction in fig. \[fig:MD\](b) shows a similar, but somewhat weaker asymptotic trend. The tendency of developing fewer defects at lower temperatures in a steady-state configuration still dominates over the effect of the external frustration.

In summary, we have experimentally determined the plastic properties of 2D dusty plasma single layers in the polycrystalline phase. The macroscopic measures, like the defect density – shear stress relation and Norton


East Friesland. This had previously been avoided, because in the clear weather the ships risked being sighted from the islands of Rottum and Schiermonnikoog and their movements reported to the British. It was assumed that the British would now be alerted to the movements of the German ships.

The British already knew that the German fleet had sailed at midday. More information arrived at 20:15, when an intercepted wireless message gave the information that they were headed for Yarmouth. At 15:50, the British fleet had been placed on two hours readiness and at 19:05 were ordered to sail south from Scapa Flow. Around midnight, the Harwich Force (Commodore Reginald Tyrwhitt) of three light cruisers and 18 destroyers was ordered to move north.

Around 20:00, German ships received a message from theof seven s, was moved from Rosyth to the Thames, together with . The presence of these ships on the Thames was given later as one reason the Harwich destroyers were not permitted to join the Grand Fleet at the Battle of Jutland: they were held back to escort the battleships should they be called upon to take part.

Casualties
The raid infuriated the British and it damaged German prestige in world public opinion, as the operation brought back memories of the 'baby killer' raids earlier in the war. British casualties were 21 British servicemen, who were killed at sea. A serviceman and three civilians were killed and 19 were wounded at Lowestoft.

See also
 Raid on Scarborough, Hartlepool and Whitby (1914)
 Raid on Yarmouth (1914)

References

Bibliography

External links
 Richthofen.com Germany's High Sea fleet in


of them? Indeed, do you see yourselves as essentially Evangelicals or as essentially 'Anglicans'?"

Those who answer the latter are, I fear, already absorbed into a theological framework dominated by Liberalism (see The Unhappy Fate of Optional Orthodoxy, by Richard John Nehaus - apologies for the format!). Only an Evangelicalism which is critical of the Anglican establishment more than it is critical of other wings of Evangelicalism is sufficient for the day. I look in vain for such criticism, though, from Fulcrum, at least.

It does strike me that open evangelicals have been absolutely marginalised by the NEAC organisers - if none of the bishops speaking at the post-Lambeth meeting actually attended the Lambeth Conference, then those committed to the Keele process of working with the whole of the Churchof England and taking the Anglican Communion seriously are going to feel very awkward about attending.

Evangelicalism has changed in recent years, and Fulcrum was formed as a response to the changes, and is not itself a cause.

Hmm, but should we be defining ourselves by who or what we criticise? I prefer to self define in terms of love (1John 4 7-12).

Fair do's, I don't go to Chelmsford DEF, but that's partly because of time (or lack of it) and partly because I am plugged in to the New Wine Network which is more enjoyable because it is less political. For example the CDEF relaunch with Pete Broadbent was an attractive idea but it clashed with parish stuff that I couldn't avoid.

Essentially I am a Christian. that Christianity is


as a result. So it should be possible, unless having (or not having) women as bishops is a requirement of the gospel, to respect and allow for the difference - which, as Pete Broadbent has taken pains to understand and state, is why what General Synod has currently proposed is wrong.

As to the link with the 'gay' issue, there clearly is one - not that women clergy must lead to gay inclusion (though you might ask Christina Rees about that one), but that 'corner cutting theology' in one area leads to corner cutting in others.

To close, my reason for my initial post is that I see (and remember, perception is fundamental) a knee-jerk tendency to criticize and complain about anything 'Conservative' on the part of some Open Evangelicals,evangelical group (with great reluctance given past encounters with some of the committee members). I certainly was critical in the meetings I attended because I just couldn't agree with the approach being adopted which was one of oppostionalism and constant criticism of the bishops, diocesan structures and other colleagues. I remember one meeting that went on for nearly three hours and which was just one moan after another about the diocese, bishops and others. So yes I was critical because I was astonished at the negativity, at times pettiness (e.g. over what bit of cloth we wore round our necks at ordination) and what I felt was a continual pursuit of confrontation. Is it a surprise that I wasn't that enthusiastic about attending the meetings and in the


case of GAFCON) having a go at others with virtually the same views - just because Reform was broadly supportive.

Criticism can be picky and petty (like Fulcrum boards picking on Reforms sense of humour - Oh come on!) but can be constructive, even if painful. For instance, John has talked about DEFs tackling the fact they've appealed to a narrower group.

IF as Fulcrum has claimed Evangelicalism has been broad, all the more reason to stick to NEAC and DEF. Fine set up a special intrest group. But to say there has been a narrowing process, just doesn't match history. Church Soc has doctrinally stood still since 1830s (when formed) and was involved in setting up CPAS, Pathfinders and DEFs. Those groups probably are now 'broader' that Church Soc.would not speak, but I would be very surprised if nobody was available and willing, and I for one would have been far happier and far more convinced this really was an attempt to gather the constituency if somebody like Nick Baines, (who blogged so helpfully from Lambeth) was speaking.

Of course you are right to point out in your second short reply that Pete Broadbent and Christina Baxter are going to represent the OE side, but again this does not address the point that there is nobody who attended Lambeth.

Darren,

If your post was in response to my comments, can I just say that of course it is right that there should be CE speakers. My objection is the absence of Lambeth attenders in a conference that is, in


I guess we all have to do that sometimes.

As I have mentioned before, Evangelicals are like the Pharisee's. Wrapped up in their own agenda's and wasting time and effort by arguing about a topic that prevents them from doing the actual thing they are arguing about. There are some bigger issues here at play like gay clergy etc etc and these issues have a dramatic effect on Evangelicals. The Gospel is simple and the life of faith once repentance has taken place is a journey but why oh why does the church seem to be able to make it so complicated and so unattractive. Any outsider looking in at all this would surely be put off?fill_in "requirement_maximum_people", with: max_ppl
      fill_in "requirement_minimum_people", with: min_ppl
      click_on 'Create Requirement'
      expect(page).to have_content "Requirement was successfully created."
      expect(page).to have_content @skill.name
      expect(page).to have_content "#{desired_ppl}"
      expect(page).to have_content "#{min_ppl}"
      expect(page).to have_content "#{max_ppl}"
      visit task_path(@task)
      click_on @skill.name
      expect(page).to have_content @skill.name
      expect(page).to have_content "Desired People: #{desired_ppl}"
      expect(page).to have_content "Minimum People: #{min_ppl}"
      expect(page).to have_content "Maximum People: #{max_ppl}"
    end
  end
end


5% glucose solution, no increased cell death was found (P =.94, n = 12), nor when infracyanine green was added (P =.13, n = 12). The observed toxicity of indocyanine green on RPE cells is probably related to the hypo-osmolarity of the solvent and may be avoided by using infracyanine green dissolved in glucose 5%.mitochondria through the mediation of Hsp60 and induces apoptosis as a consequence of mitochondrial damage^[@CR17]^. This recent finding showed that in the absence of mutations, higher FUS levels also represent a critical event in FUS-proteinopathies. Consistent with this finding, sequencing of the 3′-untranslated region (3′-UTR) of *FUS* mRNA in ALS patients, with no mutations in the currently known ALS-associated genes, identified four mutations linked to a marked increase in the accumulation of FUS^[@CR18]^, indicating that not only the nuclear--cytoplasmic imbalance of the mutant FUS, but also alterations in the physiological levels of the wild-type (wt) contribute to the pathogenesis of ALS.

Research over the past decade has revealed that FUS is a RNA-binding protein of the FUS, EWSR1, and TAF15 (FET) family, is 526 amino acids long, and is


eye disc-specific GMR-Gal4 triggers negative feedback on endogenous dFUS expression. However, a reduction of dFUS amount may not contribute to the hFUS toxicity because previous studies have shown that dFUS knockdown can induce a mild degeneration of adult eye compounds^[@CR41]^ while the phenotype herein observed was more similar to the aberrations caused by dFUS overexpression^[@CR9]^.Figure 2Abundance and solubility of endogenous dFUS are altered by hFUS expression. **(A**,**B**) Western blot analyses with an anti-dFUS antibody were performed using proteins extracted with lysis buffer from the adult heads of 6-day-old flies developed at 28 °C after eclosion. Two independent protein extractions, each loaded in duplicate for a total of four western blots, were statistically analyzed with GraphPad Prism 7.0. dFUS protein levels were normalized with respect to those of actin (\*\*p-value \< 0.005).region of eye imaginal discs with a dominant cytoplasmic localization of large and randomly sized hFUS-immunoreactive spots (Figure [S4f and f'](#MOESM1){ref-type="media"}), a smaller area of the hFUS immunoreaction with a distinct punctate cytoplasmic pattern was revealed in flies carrying *GMR/*+;*hFUS/*+;*hsrω IR/*+ (Figure [S4i and i'](#MOESM1){ref-type="media"}). Thus, in flies co-expressing hFUS mRNA and *hsrω* dsRNA, weak staining appeared to be due to the smaller amount of hFUS and the diverse hFUS-immunoreactive arrangement may agree with its insolubility.

As discussed above, since it currently remains unclear whether hFUS toxicity depends on its ability to form insoluble particles, these results represent an important step towards clarifying this issue. Based on the results in flies co-expressing hFUS mRNA and *hsrω* dsRNA showing that the rescue of toxicity coincides with both the establishment of insoluble hFUS


hFUS aggregates play a significant role in hFUS toxicity. Therefore, we considered the second effective mechanism triggered by *hsrω* depletion to rescue hFUS toxicity to be the elimination of hFUS relative soluble aggregates trough the formation of LAMP1-targeted hFUS insoluble inclusions.

The novel results of the present study suggest a new *scenario*; a lncRNA-dependent mechanism may control the formation of non-toxic FUS inclusions. Under these conditions, the mis-regulation of some lncRNAs may not only be a consequence of FUS aggregate formation, as previously proposed, it may also be an instigating event of FUS-proteinopathies such as alterations in FUS expression and specific targeting/packaging into harmless deposits.

Methods {#Sec10}
=======

Fly stocks {#Sec11}
----------

Fly stocks were maintained at 25 °C on standard food containing 0.7% agar, 5% glucose, and 7% dry yeast. Canton S was usedwere incubated with the following primary antibodies: mouse monoclonal anti-hFUS (1:50, Santa Cruz sc-47711), rabbit polyclonal anti-LAMP1 (1:100, Abcam ab30687), rabbit mono-specific synthetic peptide anti-cleaved caspase-3 (CC3) (1:00, Cell Signal Asp175-5A1E), and rabbit polyclonal anti-Hsp70 (1:100, Enzo ADI-SPA-812), at 4 °C for 16 h with agitation, and, after washing with PBT, they were treated with the fluorescent-conjugated secondary antibodies Alexa-488 anti-rabbit IgG (1:400, Invitrogen) and Alexa 594 anti-mouse IgG (1:400, Invitrogen) at 25 °C for 2 h. Staining with fluorescein isothiocyanate (FITC)-conjugated goat anti-Phalloidin (Pha) (1:1000, MP Biochemicals) was used at 25 °C for 30 min. All primary and secondary antibodies were diluted in PBT-2% NGS. Samples were mounted in Vectashield (Vector Laboratories-Inc.) and observed under a confocal laser-scanning microscope (OLYMPUS FLUOVIEW FV10i). Images were analyzed with MetaMorph Imaging System 7.7 (Molecular Devices Inc.).

Solubility


test {#Sec15}
---------------

Total proteins were fractioned according to their solubility by adapting the protocol described previously^[@CR40]^. One hundred *Drosophila* adult flies were frozen in liquid nitrogen, and the heads were separated by 45 s of vigorous vortexing and homogenized in 350 µl Low Salt buffer containing: 10 mM Tris, 5 mM EDTA, and 10% sucrose, pH 7.5. Homogenates were centrifuged at 2000 x *g* for 10 s. Fat and cuticles were discarded, and 50 µl of the homogenate was set aside as input (INP). The remaining 300 µl was centrifuged at 25000 x *g* at 4 °C for 30 min. The supernatant from this step was collected as the soluble fraction (LS). The pellet was further extracted with 150 µl ionic detergent buffer containing: 10 mM Tris, 5 mM EDTA, 2% N-Lauroylsarcosine (Sarkosyl), and 10% sucrose, pH 7.5 and then centrifuged$c\neq 0$ and $t_v<k$ for all $v\in V(G)$, then $(G,\sigma)$ is $k$-choosable. Thus, the notion of Alon-Tarsi number of unsigned graphs defined by Jensen and Toft [@Jensen1995] can be naturally extended to signed graphs.

\[AT\]

Parallel to the unsigned case, we have $$AT(G,\sigma)\ge \chi_l(G,\sigma)\ge \chi(G,\sigma).$$ For a subgraph $H$ of $G$, we use $(H,\sigma)$ to denote the signed subgraph of $(G,\sigma)$ restricted on $H$, i.e., $(H,\sigma)=(H,\sigma|_{E(H)})$. Note that $P_{H,\sigma}(\bm{x})$ is a factor of $P_{G,\sigma}(\bm{x})$. From Definition \[AT\], it is clear that $AT(H,\sigma)\le AT(G,\sigma)$.

For a vertex $v$ in a signed graph $(G,\sigma)$, a *switching* at $v$ means changing the sign of each edge incident to $v$. For $X\subseteq V(G)$, a switching at $X$ means switching at every vertex in $X$ one by one. Equivalently, a switching at $X$ means changing the


and $2$-colorable then $AT(G,\sigma)\le 4$. Moreover, there is a signed planar graph which is $2$-colorable but not $3$-choosable.

Orientation and Alon-Tarsi number for\
signed graphs
======================================

For an unsigned graph $G$, Alon and Tarsi [@Alon1992] found a useful combinatorial interpretation of the coefficient for each monomial in the graph polynomial $P_G(\bm{x})$ in terms of orientations and Eulerian subgraphs. By defining hypergraph polynomial and hypergraph orientation, Ramamurthi and West [@Ramamurthi2005] generalized the result of Alon and Tarsi to $k$-uniform hypergraph for prime $k$. In this section we consider the signed graphs. Instead of using orientations of signed graphs, we use orientations of the underlying graphs and find that the result of Alon and Tarsi has a very natural extension for signed graphs.

Let $(G,\sigma)$ be a signed graph and ‘$<$’ be an arbitrary fixed$D$ such that each outdegree is at most $AT(G,-)-1$. Thus, by Lemma \[madori\], $\textup{mad}(G)\le 2(AT(G,-)-1)$, i.e., $AT(G,-)\ge \frac{\textup{mad}(G)}{2}+1$. Therefore, $AT(G,-)\ge p+1$ since $AT(G,-)$ is an integer. This proves the corollary.

*Proof of Theorem \[AT4\]*. For a signed graph $(G,\sigma)$, Schweser and Stiebitz [@Schweser2017] showed that $\chi(G,\sigma)\le 2$ if and only if $(G,\sigma)$ is switching equivalent to $(G,-)$. Thus, by Proposition \[equAT\], it suffices to consider the case when $(G,\sigma)=(G,-)$, i.e., $\sigma(uv)=-1$ for each $uv\in E(G)$. Let $H$ be any subgraph of a planar graph $G$. Then by Euler’s formula for planar graph we have $2|E(H)|/|V(H)|\le 6$, i.e., $\textup{mad}(G)\le 6$. By Corollary \[negative\], $AT(G,-)\le 4$. This proves the first part of Theorem \[AT4\].

Let $(G,-)$ be the negative planar graph as shown in Figure 2. We show that $(G,-)$ is not