Lee [@CR52]).

Resistin, although classified as an adipokine, in humans is expressed in macrophages and plays important roles in inflammation throughout the body. Its serum level is increased in cardiovascular disease (Karbowska et al. [@CR30]; Reilly et al. [@CR48]), other inflammation-related diseases (Pang and Lee [@CR43]) and in diabetes (Rajala et al. [@CR47]), however, studies relating human resistin to insulin resistance, or diabetes have shown conflicting results.

The impact of resistin on the physiology and the pathophysiology of the central nervous system remains poorly defined. The potential protective effects of resistin against Aβ neurotoxicity in mouse cells which overproduced Aβ was stated by Liu et al. ([@CR38]). The results of the two clinical studies are inconclusive. A recent study of Mirabell et al. ([@CR40]) suggested that resistin was not related(Karbowska et al. [@CR30]). Some authors stated that it was secreted as a marker of chronic inflammation (Bo et al. [@CR8]; Olefsky and Glass [@CR42]) and on the other hand it was considered to be a factor causing enhanced production and secretion of pro-inflammatory cytokines (Silswal et al. [@CR50]).

Another interesting finding in our study is the significant positive correlation of resistin level with serum chitotriosidase activity stated in all patients with dementia, particularly in dementia with vascular changes. Chitotriosidase (CHIT1) is an enzyme involved in the degradation of chitin and chitin-like substrates. CHIT1 activity is increased in several lineages of activated macrophages which are involved in both physiological and pathologic processes. CHIT1 expression is altered in a number of non-infectious inflammatory diseases. Being a nonspecific marker of macrophage


healthcare plan work.

I know so far God’s in control and we have to trust that God is going to give this new administration the time wisdom to make it all work.

The Trump Cabinet

President Donald J. Trump has formally announced that the 24 people listed below will be serving with him on his Cabinet.

Vice President Michael R. Pence

Secretary of State Rex W. Tillerson

Secretary of the Treasury Steven T. Mnuchin

Secretary of Defense James Mattis

Attorney General Jeff Sessions

Secretary of the Interior Ryan Zinke

Secretary of Agriculture-designate Sonny Perdue (announced)

Secretary of Commerce Wilbur L. Ross, Jr.

Secretary of Labor-designate Alexander Acosta

Secretary of Health and Human Services Thomas Price

Secretary of Housing and Urban Development Benjamin S. Carson, Sr.

Secretary of Transportation Elaine L. Chao

Secretary of Energy James Richard Perry

Secretary of Education Elisabeth Prince DeVos

Secretary of Veteransit clear that his decision applied nationwide, ruling that the ban could not be enforced at any U.S. borders or ports of entry or in the issuance of visas.

Nominated to the federal bench by President Barack Obama in 2012, he is currently the only Native Hawaiian judge serving on the federal bench and the fourth in U.S. history. He received his law degree from Harvard in 1991.

In Maryland, attorneys told a federal judge that the measure still discriminates against Muslims.

Government attorneys argued that the ban was revised substantially to address legal concerns, including the removal of an exemption for religious minorities from the affected countries.

“It doesn’t say anything about religion. It doesn’t draw any religious distinctions,” said Jeffrey Wall, who argued for the Justice Department.

Attorneys for the ACLU


a trillion dollars (or more) of our wealth will have left the United States for good.

17) All of this wealth leaving the United States is having a huge impact on the standard of living of average Americans. Ten years ago, the United States was ranked No. 1 in average wealth per adult. In 2010, the United States has fallen to seventh.

18) It is now just a matter of time until India is going to pass us as an economic power. In fact, the economy of India is projected to become larger than the U.S. economy by the year 2050.

19) It is now being projected that China will soon dwarf us as an economic power. One prominent economist now says that the Chinese economy will be three times largerthan the U.S. economy by the year 2040. According to one recent study, China could become the global leader in patent filings by next year.

20) China has been accumulating a gigantic mountain of dollars from all of the wealth we have been sending them each month, and they have been lending massive amounts of money back to us. Over the past few decades, the communist Chinese have been able to accumulate approximately $2.5 trillion in foreign currency reserves, and the U.S. government now owes them close to $900 billion. We constantly have to send top government officials over there to beg them to continue to lend us money. This is a direct threat not only to our financial system, but also to our national security.

Judging from Obama’s comments


a phony and just found some proof. The Supreme Court must act responsibly and without pause to remove the phony without delay, as The Constitution of the United States dictates.

“I’m naturally inclined to think of it in those terms,” said Thiel on the topic of how Trump’s victory showed the American people’s dissatisfaction with globalization. “There’s something around globalization that’s not been working that well.”

“The internet was designed to survive a nuclear war, but even so, I think there are a lot of regulatory challenges that Silicon Valley will be facing from Western Europe and elsewhere in the years ahead,” he continued. “There’s a technological determinism story you can tell where this is the future and China will eventually buckle under and cave and eventually adopt all ofonly that – she explains very clearly the origin of the devil´s number(666 = 6+6+6 = 18) being 18 years long from 1999-2017 called ”Cain´s Age” – The Age Of Murder.

Cain´s Age – The Persecution Of Falun Gong(1999-2017)

Therese Neumann also explained that Cain´s Age will imply the ”slaughter of the pious men, men of understanding.”

We all know that there is only one mass persecution of ”pious men” going on in the world since 1999 to 2017: The persecution of Falun Gong! Hence, Therese Neumann reveals the real truth in plain sight here for everyone to see. The Beast which persecutes Falun Gong is of course the ”Chinese Communist Party” which has been a death machine since its foundation in 1949.

In her prophecy we may finally decipher the Number


gives us two hints: 13 is an unlucky number and 18 signifies the number of years of persecution giving our theory further credibility.

Therese Neumann – Summary Of Her Most Interesting Prophecies

The most significant part of Therese’s predictions affect our current time. At the end of World War II, when people cheered for the end of dictatorships (an end that Teresa had prophesied when the ”Pact of Steel” was entered on the eve of the conflict between Italy and Germany ) she said,., ‘this is justified joy, because the nightmare is over .. but the great plague will open in 1999 and it will bleed for eighteen years: this will be the time of Cain(the murderer)”.

”On the highest throne – Teresa confided to a friend – I saw seatedin the great Universe. The Universe will always be more powerful and intelligent than the human beings. Yet it seems like human beings always forget their frailty and due to their pride destroy this earth in order to obtain a little bit of ”comfort” and fulfilling their ”carnal desires” during their human life. It seems like every civilization is terminated in the same way with some kind of cataclysmic event cleansing all evil people and the earth before restarting a new civilization.

If you read this article it means that you can position yourself on the right side. Knowing what will come and the reasons for it will make it possible for you to position your mind correctly and be mentally prepared.


in gait and balance that occur when incorrect information is given visually.

SUBJECTS AND METHODS {#s2}
====================

Fifty healthy volunteers were recruited: 25 young male adults (age = 21.68 ± 1.91 years, weight = 66.60 ± 6.63 kg) and 25 young female adults (age = 21.04 ± 0.98 years, weight = 54.76 ± 6.80 kg). The subjects were chosen because they did not have any alcohol-related disorders, visual perception problems, gait problems, neurological diseases, or orthopedic disorders. The study objectives and procedures were explained to the study subjects, and their consent to participation in the study was obtained. The ethical committee of Kangwon National University's institutional review board approved the study.

In this study, virtual drunk experience goggles were used to generate visual disturbance. The Drunk Busters Goggles used in this study were patented in theUSA (Patent No. 6206521). They simulate the effects of visual distortion, viewing angle reduction, and confusion, making wearers feel as if they have an alcohol-induced drunken feeling. The goggles have three levels of visual disturbance which simulate blood alcohol concentrations (BAC): low BAC (0.07--0.10%), medium BAC (0.17--0.20%), and high BAC (\>0.25%). The higher the blood alcohol concentration, the more severe the visual distortion and disturbance. The subjects in this study wore no goggles and goggles with visual disturbance levels associated with low, medium, and high blood alcohol concentrations, and visual perception as well as balance and gait performance were measured. First, a correlation analysis between goggle type and visual perception was conducted to determine whether the virtual drunk experience goggles disturbed visual perception. The results show that the


bullshit over the parlour tricks and ramble mysteriously about the "wisdom of crowds", hold cryptic objects up to the camera when trailing your programmes, speak in an odd way and repeat or emphasise certain words in an unnatural manner as if this holds some mysterious significance. Strike just the right note of hollow pseudoscientific significance and the punters will lap it up.

Just to be clear, I'm quite confident Derren Brown himself views what he does as a series of parlour tricks dressed up with a bit of flummery to get the punters in. As he himself says, just to have people wondering if he could really predict the lottery numbers (check out the byline on the Daily Mail article - now that's magic) or work out which gunrents for himself. He also permitted a policeman to erect a structure and keep his police dog on the property. In the early 1950's Hardesty & Johnson erected a sign advertising a subdivision Lynn Havenand he knocked it down the same evening it was erected. Sometime after this occurrence, Hauschulte Realty Co. and the Nooney Realty Co. erected signs on the property and he knocked them down also. Sometime in 1972 some men commenced removing some maple trees from the property and he ordered them off of the property.
There was also testimony by Jack and Sue that approximately three months after *633 he built the house Harold told him that he had a farm in Dexter, Missouri, which he would let Jack have if Jack moved off the


man, testified that he prepared their income taxes, that he never took off any deductions for real estate taxes, and that on one occasion Jack told him he did not have to worry about paying any rent. Ralph Bastean testified that he rented six acres of the farm from appellants in 1972, farmed it, and paid the rent to appellants. Joseph Montrey testified that he has known appellants for thirty years or more and although Jack never told him that he owned the Dunn Road property he had the understanding from conversations around the tavern he owned that Jack's mother owned the property. Herman Kienstra, who has known the appellants since around the late forties or early fifties, testified that he furnished some ready-mix concrete, sand and cementmemories – we’re forgiving with them, and forgetful. Thirteen years of distance can’t weaken the iconic hums of Halo: Combat Evolved’s menu music, nor can a decade make you forget how you felt when you scored that last amazing flag capture on Coagulation. But you’ve probably forgotten about everyone’s blocky mouths, the flat textures on walls and floors, and the toothless explosions. It was all fine at the time, anyway.

That’s not to point out failures on Bungie’s part. Expecting a game’s sights and sounds to hold up after two console generations of technological advancements is beyond unfair. Still, times have changed. The bar is higher. These lesser “faults” won’t (and can’t) kill what makes Halo so special, but they are small and constant reminders that Master Chief has


need to pick sides. Second, there will always be a place for great shooters with immersive worlds, and respect for the power of intrigue and mystery in storytelling. There’s a place for Halo.

What’s that great quote from the Halo novel? Oh yeah.

“Didn’t you know? Spartans never die.”

BONUS: Interesting Facts About Master Chief Collection

We asked and are awaiting confirmation on whether or not Master Chief Collection will support digital pre-ordering/pre-loading.

Halo 3 and Halo 4 make use of the Xbox One controller's impulse triggers out of the box (we experienced it!), and Halo: CE and Halo 2 may have that functionality added in via a game update shortly after release.

The Scorpion tank still lives in the Coagulation Anniversary remake, but you have to turn it on in Forge (more onor adjust the bandwidth occupied by each ONU in each frame until every m frames have elapsed, where m is an integer greater than 1 and is generally an integer multiple of 2. As shown in FIG. 1, the update period of the DBA is 8 frames. In non-measurement periods, the bandwidth occupied by ONU1 in one frame (125 us) is only M us, for example, M=25. ONU1 transmits data in the 25 us time. For the purpose of measuring the Received Signal Strength Indicator (RSSI) for ONU1, a bandwidth of a continuous time bucket needs to be allocated to ONU1 and the continuous time bucket is greater than the 25 us in each frame (125 us), for example, bandwidth of at least 100 us. In order for


the DBA module to allocate bandwidth of at least 100 us to ONU1, the bandwidth occupied by other ONUs in the same OLT will decrease accordingly. The bandwidth occupied by each ONU keeps unchanged in an update period of a DBA, namely, the DBA allocates bandwidth of at least 100 us to ONU1 in each frame in an update period of the DBA. Therefore, only the remaining bandwidth in each frame is available to other ONUs in the update period of the DBA. As shown in FIG. 1, during the period of measuring the RSSI, within an update period (8 frames) of the DBA, ONU1 occupies at least 100 us in each frame. In practice, it takes only 100 us to measure the optical power. That is, therevolt to realise freedom, exists in every being; I should say that it exists in some form and to some degree in the smallest particle that composes matter, but ages of priest- and State- craft have almost smothered it, and ages of alleged democracy, of triumphant Social Democracy even, are not likely to kindle it again.

Here Bakunin”‘s Socialism sets in with full strength mental, personal, and social freedom to him are inseparable—Atheism, Anarchism, Socialism an organic unit. His Atheism is not that of the ordinary Freethinker, who may be an authoritarian and au anti-Socialist; nor is his Socialism that of the ordinary Socialist, who may be, and very often is, an authoritarian and a Christian; nor would his Anarchism ever deviate into the eccentricities of Tolstoi and Tucker.


ever made, and the necessity of replacing semi-authoritarian proceedings like that of Bakunin by the free play of individual initiative or other improved methods, never seems to arise.

Bakunin”‘s best plans failed from various reasons, one of which wee the smallness of the means which the movements, then in their infancy, offered to him in every respect. Since all these possibilities are a matter of the past, let me dwell for a moment on the thought of what Bakunin would have done had he lived during the First of May movements of the early “nineties” or during the Continental general strike efforts of the ten years next following With the tenth part of the materials these movements contained, which exploded some here, some there. Like fireworks, in splendid isolation,of Anarchism to a minimum; but when Italy, Spain, and France were silenced, some corner in Switzerland where Bakunin”‘s seed had fallen always remained, and in this way, thanks to the solid work of Bakunin and his comrades, mainly from 1868 to 1874, Anarchy, was always able to face her enemies and to revive.

The immediate influence of Bakunin was reduced after he had retired from the movement in 1874, when certain friends left him; bad health—he died in June, 1876—prevented him continuing his work with fresh elements gathered round him. Soon after his death a period of theoretical elaboration began, when the methods of distribution were examined and Communist Anarchism is its present form was shaped. In those years also, after the failure of many collective revolts, the


in many other countries was in its vigorous youth, a period when the tendency to look ahead is greatest, and the past is neglected like a cradle of infancy. For this reason, and because very little information on Bakunin was accessible to the Anarchists of the “eighties,” Bakunin”‘s influence in those years remained small. I ought to have mentioned that certain opinions of Bakunin”‘s gained much ground in the Russian revolutionary movement of the “seventies” and later, but cannot dwell further on this.

In 1882, Reclus and Cafiero published the choicest extract from the many manuscripts left by Bakunin: “Dieu et Etat!” (God and the State), a pamphlet which B. R. Tucker fortunately translated into English (1883 or 1884). This or its English reprint circulated in England when noV-pulse P@MTR-R P-wave at maximum tracking rate followed by a R-wave MAGNET Magnet placed over the implanted device--either singly or in combination with an external telemetry system ______________________________________
U.S. Pat. No. 5,431,691 to Snell et al. entitled "Method and System for Recording and Displaying a Sequential Series of Pacing Events" provides a detailed description of the operation of the APS II system of Pacesetter Inc. including a description of the processing and displaying of the diagnostic information set forth in TABLE I. In particular, the Snell et al. patent describes a technique whereby the pacemaker processes and records diagnostic data in the form of "event records" which allow the data to be efficiently stored within the pacemaker, transmitted to the APS II system, and displayed. U.S. Pat. No. 5,431,691


not the perfect student.

“I'm useless with game plans. That's probably the one thing he just gets so frustrated with me about,” Sharapova, who will take over from Victoria Azarenka as world number one if she reaches the final in Paris, told a news conference.

“I go out there and I do my own thing, and then he's like, after the match, 'Really? What's the point of having me?'

“But I apologised when I hired him in advance, so he's okay.”

There was nothing Hogstedt could do, however, about the swirling winds that disrupted play on Court Philippe Chatrier.

Twenty-one of the 30 games went against serve as the players sometimes struggled to throw the ball properly and the geranium displays took a beating from gusts of wind.

“The conditions were difficult, so itresponded.

“Prophiter,”
I said to him.

“And when
were you born?” he continued.

“The 16th
of Evening Star.”

“Alright.,
and your trade?”

“I’m an
acrobat.” An acrobat, the usual alias of a thief. It wasn’t really a
lie.

“Hmm, well
Prophiter, that should be enough. You’ll take these papers through to
the next building.”

I
followed his instructions and continued to the next building. There I
found another imperial; this one with more impressive armor. It was
golden, or maybe brassy coloured, with red cloth lining. Very
expensive looking. I figured he must have killed a lot of people to
get such a suit of armor. At first, he said nothing to me and instead
he just took the papers from my hand.

“So…Prophiter,
my name is Sellus Gravius, but my background is not important. All
that’s important is that you follow your orders and do not get into
trouble. You will begin


go now, and you can be in Balmora by this afternoon. Complete
your task and you will be cleared of your charges and allowed to
return to Cyrodiil. If you betray these orders, you will be betraying
the Emperor, and you will suffer the fate of all traitors. Remember,
we will be keeping our eyes on you.” He stared at me, sternly, as if
waiting for a response. His eyes were very serious, and he stood
still like a rock. I couldn’t help but smirk somewhat.

“Gotcha,”
I said before exiting from the building. I stood outside on the
streets, or street of Seyda Neen, and reflected upon my new mission:
to infiltrate the Thieves Guild. I didn’t think that would be too
hard. What Captain Gravius apparently didn’t know, was that I was
already a member. I had beenthere in Seyda Neen. I saw mostly
Dunmer and Imperial guards, but there were a few other elves about.
One of them approached me.

“Hello.
Are you off an Imperial prison ship as well?” the Bosmer said to me.
I was somewhat startled, as he came up from behind me. I turned
around though, and responded.

“Huh?” I
queried.

“Well, by
those dirty clothes I just assumed that you were another prisoner
being released. By the Imperials, that is. They’ve been doing that a
lot, recently. Well, are you?” he asked, with optimistic, cocked
eyebrows. I looked down at the clothes that I had been wearing for
the last two weeks and realized that he was correct; they were dirty.
I then responded.

“Yes, I
am. Who are you?”

“Oh!
Forgive me. My name is Fargoth. And yours?” I did not forgive him.

“Prophiter,”
I said.

“Well,
Prophiter, now that we’ve


if there was anything he could
help me with. I held up my end of a conversation that was of no
interest to either of us. As we spoke, I spotted a few items that
would be of use to me.

“Fargoth
actually recommended that I come here. You two…are friends?” I asked.
His face made a quick look that was a mix of recognition and
contempt.

“Yes…I
know Fargoth,” was his response. “How long will you be staying in
Seyda Neen?” he asked.

“Oh, not
long. Then I’ll be heading to…Balmora,” I said to the Altmer.

“To
Balmora?” Arrille asked unnecessarily. I nodded, noticing a map
pinned to the wall, to the side of Arrille.

“Do you
suppose…that you could show me the best route to take on that map
there?” I asked. The Altmer turned, and I swiped the short sword that
lay on thetable beside me. He examined the parchment, and I fit the
blade in the back of my pants, underneath my shirt. I then moved
towards him, and leaned in to where he was pointing.

”If you
began leaving the town here…” With his long, elegant, fingers, he
pointed to a path that led directly from Seyda Neen to the city of
Balmora. “…and that will lead you to Balmora,” he finished.

“Excellent,”
I proclaimed, having just lowered a few gold coins into my pocket.
“Well, thank-you for the advice. I think I’ll leave right away.” I
left the shop and made my way to the exit from Seyda Neen. I didn’t
know the terrain or the wildlife of Morrowind well, but that wasn’t a
problem. I knew the way, and that was enough for me. As I walked out
of town


the innate immune system in vertebrates. The only human cathelicidin identified to date is LL-37, which derives from its precursor protein hCAP18 through proteolytic cleavage^[@CR18]^. The respective homologue in mice is cathelicidin-related antimicrobial peptide (CRAMP). LL-37 was detected in neutrophils and other leukocyte populations (i.e., lymphocytes, monocytes, and eosinophils)^[@CR19]--[@CR22]^. It is also present in tissues, where high local concentrations can be reached^[@CR23]^. LL-37/CRAMP exerts broad antimicrobial effects in response to bacterial^[@CR24]^ and viral infections^[@CR25]^ and, dependent on the context and leukocyte subset involved, both pro- and anti-inflammatory effects of this peptide have been described^[@CR26]^. These complex and differential functions were assigned to the ability of LL-37 to activate a broad variety of receptors including the formyl peptide receptor (FPR2), chemokine (C-X-C motif) receptor 2 (CXCR2), or purinergic receptorsconditions and acute thrombosis.

Discussion {#Sec10}
==========

We report here that hematopoietic LL-37/CRAMP induces platelet activation and secretion, which mediates platelet--leukocyte aggregate formation and neutrophil recruitment at sites of inflammation. We identified LL-37/CRAMP in thrombi and demonstrated that depletion of CRAMP reduces the development of arterial thrombosis in mice. Further, in a mouse model driven by platelet--neutrophil interactions, absence of CRAMP abrogated pulmonary injury. Inhibition of hematopoietic cathelicidin may therefore represent a novel strategy to reduce thrombo-inflammatory disease.

Arterial thrombosis is a common condition with high morbidity and mortality. While platelets are considered key elements of this process, immune cells have recently been identified in coronary artery thrombi of patients with AMI^[@CR12],[@CR13]^. The implications of these findings are only partly understood, but the local release of leukocyte content at sites of vascular


a cryotome (CryoStar NX70, ThermoFisher Scientific) into 10 μm sections, fixed with 4% formaldehyde and blocked with the respective serum. The sections were incubated with primary antibodies for 1 h at room temperature. Rabbit polyclonal anti-LL-37 (Cat No. PA-LL-37-100) and rabbit polyclonal anti-CRAMP (Cat No. PA-CRPL-100) antibodies were from Innovagen (Lund, Sweden), mouse monoclonal anti-human myeloperoxidase (MPO) antibody (clone 2C7) was from Abcam (Cat No. ab25989), goat polyclonal anti-human MPO antibody was from R&D Systems (Cat No. AF3174), mouse monoclonal anti-human CD41 (clone HIP8) was from Biolegend (Cat No. 303710), and rat anti-mouse CD41 (clone MWReg30) antibody was from eBioscience (Cat No. 14-0411-82). Mouse monoclonal anti-human histone H3 citrulline antibody (clone 7C10) was from Covalab (Cat No. mab0072-P) and rabbit polyclonal anti-mouse histone H3 (citrulline R2+R8+R17) antibody was from Abcamvisualization and thrombus formation was monitored for 60 min by placing the carotid artery under a fluorescence microscope equipped with a camera (AxioScope; Carl Zeiss). Fluorescent images were acquired sequentially (1 image/s) and thrombus size and kinetics (i.e., time to occlusion, duration of occlusion) were analyzed using AxioVision 4.7 imaging software (Zeiss). In some experiments, neutrophil depletion was performed before thrombus formation using a Ly6G-specific mAb (clone 1A8, BD Biosciences, Cat No. 551459). The antibody was injected intravenously at a concentration of 5 µg/g body weight (in 150 µL PBS) 24 and 6 h before induction of thrombosis^[@CR63]^.

To analyze binding of CRAMP to thrombus in vivo, 5-carboxyfluorescin (5-FAM)-labeled CRAMP peptide (Innovagen, Sweden, CAT No. SP-5352-1) or 5-FAM-labeled scrambled peptide (custom made from Innovagen, Sweden) were infused intravenously (4 μg per gram body weight


and stained with anti-human MPO antibody (Abcam), anti-human histone H3 citrulline antibody (7C10) (Covalab, France) and respective secondary antibody and DAPI to visualize NET formation. Imaging was conducted by fluorescence microscopy (Axiovert 200M microscope Zeiss, Jena, Germany) and quantitative analysis was carried out by manual counting of NET-structures per visual field of 3-5 randomly defined ROIs per sample.

Platelet preparation for cremaster experiments {#Sec35}
----------------------------------------------

Platelets were isolated from WT C57Bl/6 mice. Platelets were labeled with Rhodamine (0.05%; 50 μL/mL, Sigma) for intravital studies and with anti-GPIb-X649 (1:200; non-blocking antibody, Emfret, Germany) for post-imaging FACS-analysis. Labeling was carried out in PRP for 30 min in the presence of prostaglandin (0.5 µg/mL) to avoid activation, and platelets were then centrifuged at 400×*g* for 5 min. Isolated platelets were treated with 20 µmol/L CRAMP for 20 min. CRAMP wasin a marked sustained K+ release. ACh produced a further increase in K+ efflux in the continuing presence of ouabain. Incubation of the tissue with 10 mM-tetraethylammonium (TEA) resulted in an uptake of K+. The result suggest the presence of a diuretic-sensitive Na+-Cl- co-transport system in lacrimal acinar cell membranes.


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Just the Thing

21839

I was looking for a spare battery and charger for my/our phones and came across this. This will support both our phones as well as a few other small devices. It seems to me to do the job and I hope it continues to do so. It is cheaper and more flexible than my original solution.

Roger Reed

20th September 2014

Samsung S3 mini, KIndle, Sony eReader

Aberdeen

Good and does as it says in the tin lol

24149

Works fine. Some user guides would have been useful. Delivery good

Zoe small

13th July 2014

Kit power junkie twin usbbportable charger

Corby

What I needed but something important missing

24376

Received the charger but no power lead so I basicallyrisk damage to the motherboard. Use it ONLY for charging from your battery pack.
Overall, a decent battery pack, well made with a large capacity. Just be prepared for slow charging times for a smart-phone if you are not prepared to hack into a standard USB cable.

Will

21st October 2010

Nottingham

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Wire Guards & Shields

At Emergency Lights Co., we understand that outfitting your property with exit signs, emergency lights and combo units can be a significant investment of time and financial resources. Also known as cages, wire guards are perfect for gyms, garages, and other applications that face moderate levels of abuse. We’re committed to reducing the cost and effort required in meeting compliance strictures, and provide the products and accessories to help make this happen.

To avoid the cost and hassle involved in replacing emergency lighting and signage, we strongly recommend the use of wire guards or polycarbonate shields.

Easy to install and extremely long-lasting, wire guards provide an important protective barrier between your exit signage and anything that might impact or alter it. An ideal choice for athletic facilities,The following is a “No Frills” walkthrough of
this freeware game, with minimum (vital) description & verbiage.

In a few places the action is not essential
but helpful … these are highlighted in blue. Some actions take place in
inventory … these are highlighted in pink.

After each essential
action, the number of points is included in curly red brackets. No cumulative
score is given since many actions can be done in different orders yielding
different numbers of accumulated points.

If you follow the order I played the game as
below and perform all the actions described, you will obtain the full 205 points
(out of a maximum of 205).

If you play in any different order but perform
all the actions described below, I see no reason why you should not obtain the
full 205 points also !


1991 World Championships in Athletics – Men's long jump

These are the official results of the Men's Long Jump event at the 1991 IAAF World Championships in Tokyo, Japan. There were a total number of 43 participating athletes, with two qualifying groups and the final held on Friday August 30, 1991.

Medalists

Analysis
This was perhaps the greatest long jump competition ever as both of the top two athletes achieved distances beyond the then world record which had stood for almost 23 years (though one was over the wind-legal limit of 2.0 m/s).  Both made the best wind-legal jumps of their careers in this competition; the still best and still third best wind-legal jumps in history; and the best two long jumps not aided by altitude.

Carl Lewis' record at the timein *S. aureus* infections ([@B4]--[@B8]). Ordered *S. aureus* PSMs aggregate into amyloid-like fibers can facilitate biofilm structuring, thereby protecting *S. aureus* from immune systems ([@B9]--[@B13]). While monomeric PSMs will disperse biofilms ([@B14], [@B15]). More importantly, PSMs can modulate immune response using aggregation as a control point for their activity ([@B16]).

The proinflammatory activity of *S. aureus* PSMs is arguably the most important contribution to staphylococcal pathogenesis ([@B16]). At nanomolar concentrations, *S. aureus* PSMs attract leukocytes and initiate immune responses *via* formyl-peptide receptor 2 ([@B4], [@B17]). While in the micromolar range, *S. aureus* PSMs can cause cytolysis of leukocytes after phagocytosis, leading to the release of damage-associated molecular patterns (DAMPs) ([@B18]--[@B20]). The best characterized DAMP is a nuclear protein, high mobility group box-1 protein (HMGB1), which directs the triggering of


and response were recorded. The binding curves were analyzed using a kinetic analysis supplied with the BIA evaluation software (Biacore) ([@B11]).

Immunoprecipitation {#S2-4}
-------------------

The recombinant HMGB1 with a calmodulin-binding protein (CBP) tag was provided by Kevin Tracey (The Feinstein Institute for Medical Research, Manhasset, NY, USA) ([@B23]). The CBP-tagged HMGB1 or 10 µg CBP peptide alone was incubated overnight with 50 µL HEK-Blue hTLR4 cell lysates (precleared with calmodulin beads) at 4°C with gentle shaking. The mixture of HMGB1-CBP or CBP and HEK-Blue hTLR4 cell lysates was then incubated with 30 µL drained calmodulin beads for 1 h at 4°C. After extensive washing with PBS containing 0.1% Triton X-100, proteins bound to the beads were analyzed by immunoblotting with anti-TLR4 (R&D Systems) or anti-CBP antibodies.

Stimulation Assays {#S2-5}
------------------

Cells were stimulated with 1.0 µg/mL HMGB1 in theModeling {#S2-10}
-----------------

Homology modeling was carried out using the software package Discovery Studio 2017R2 (Accelrys, San Diego, CA, USA). The structure of PSMα1 (PDB ID: 5KHB) was found *via* BLAST and used as a template in the alignment and modeling of PSMα2 and PSMα4. PSMβ2 (PDB ID: 5KGZ) was selected for PSMβ1 modeling ([@B35]). And the three-dimensional (3D) structure of deta-toxin (PDB ID: 2KAM) was an ideal template for *S. aureus* δ-toxin. Homology model was constructed using MODELLER.

Receptor--Ligand Interaction {#S2-11}
----------------------------

ZDOCK was applied in the docking of HMGB1 (PDB ID: 2LY4) and all the *S. aureus* PSMs to TLR4 (PDB ID: 3FXI) ([@B36], [@B37]). Angular step size for the rotational sampling of the ligand orientations was set to 6, and a total of 3,000 poses were generated for each ligand-receptor


HMGB1 effectively binds to TLR4 (Figure [2](#F2){ref-type="fig"}A).

![*Staphylococcus aureus* phenol-soluble modulins (PSMs) α1--α3 attenuate HMGB1-toll-like receptor (TLR4) binding. **(A)** Mixture of calmodulin-binding protein (CBP)-tagged HMGB1 or CBP alone with the HEK-Blue hTLR4 cell lysates was immunoprecipitated (IP) with calmodulin beads, and immunoblotted (IB) with anti-human TLR4 (hTLR4) or CBP antibodies. Recombinant hTLR4 protein was included as positive control (right lane 7). **(B)** Surface plasmon resonance (SPR) analysis was performed to assess HMGB1 binding to hTLR4. HMGB1 binding to hTLR4 was tested at different concentrations (1.25, 2.5, 5.0, 10.0, and 20 µM) with a *K*~D~ value of 9.199 µM. SPR analysis of HMGB1 binding to TLR4 was performed in the presence of PSMα1 **(C)**, PSMα2 **(D)**, PSMα3 **(E)** as shown. Data were representative of three repeats.](fimmu-09-00862-g002){#F2}

Moreover, we observed significant HMGB1 binding to*S. aureus* PSMs α1--α3 inhibit HMGB1/TLR4/NF-κB signaling.

![*Staphylococcus aureus* phenol-soluble modulins (PSMs) α1--α3 inhibit HMGB1-induced NF-κB activation. **(A)** HEK-Blue hTLR4 cells were stimulated for 30 min with 1.0 µg/mL recombinant HMGB1 or *S. aureus* PSMs (PSMα1, 5 µg/mL; PSMα2, 5 µg/mL; PSMα3, 0.5 µg/mL, PSMα4, 5 µg/mL; PSMβ1, 10 µg/mL; PSMβ2, 10 µg/mL; δ-toxin, 2 µg/mL). NF-κB p65 protein and phosphorated p65 at Ser536 in the cytoplasm were assessed by immunoblotting. β-actin and LaminB were used as control. LaminB in the cytoplasm was detected to ensure that there was no contamination during the fractionation. **(B)** Phosphorylation of NF-κB in HEK-Blue hTLR4 cells challenged with HMGB1 in the presence and absence of *S. aureus* PSMs as prior described. **(C)** HEK-Blue hTLR4 cells and HEK-Blue Null2 cells (as control) were stimulated for 30 min with 1.0 µg/mL recombinant HMGB1 or *S. aureus*


Tribunal to decide on extra time

THE SMITHWICK Tribunal is expected to announce today whether it will seek additional time to investigate new information on possible Garda-IRA collusion.

The move comes as the North’s DUP Minister Arlene Foster said she will lead a delegation of IRA victims to Dublin to seek an apology from the Irish Government for what she said was the failure of the South’s authorities to adequately combat the IRA.

The Smithwick Tribunal has been asked by legal teams for the families of murdered RUC men to fully investigate new material which comprised PSNI intelligence documents alleging a previously unknown Garda officer may have been passing information to the IRA on security matters.

The tribunal which has been running for more than six years and has been holding publicis not derived from scientific observation, but was born fully hatched seeking supporting arguments. Over the coming years as scientific evidence supporting evolution continues to mount (and it is near overwhelming as I write this) I suspect that process will continue and that those organizations which now continue to deny that evolution as a scientific fact will eventually come to accept the inevitable or they will intellectually cease to exist. However, that may take another 100 years.

The concept of climate change, much more recently arrived on the scene, has followed the pattern of other unpopular scientific discoveries. Climatologists made unbiased observations of the records in nature of climate change throughout the earth’s long history. Using those records they also sought to understand why the earth over millions of


assistance dogs for veterans, part of a program by the VA to make the provision of an assistance dog an integrated part of treatment plans. In addition, FSD has partnered with the Peak Military Care Network to help provide service dogs to veterans.

Training
The majority of animals entering the program are unwanted and/or abandoned dogs rescued from animal shelters. Each dog undergoes a comprehensive health assessment and a behavioral/training assessment. Dogs are then assigned a trainer and begin the 9- to 12-month training program.

Service dogs are trained to increase independence for people with disabilities. Each dog is matched to a specific client and custom trained according to his or her individual needs. Dogs can be trained to assist a client in their mobility, as well as retrieving items,Fan: [Jonghyun] What kind of skinship do you like lately? Hug? Holding hands? Putting arms across shoulders?[Jonghyun]: More than what you expect

Fan: [Jonghyun] What skinship are you wishing for? ㅋㅋㅋㅋㅋ If you could say this wish then we could fulfill it right now ㅋㅋㅋㅋㅋ[Jonghyun]: Let's Go hahaha

Fan: [Jonghyun] I want to hear you singing…can I?JongHyun: Yup, How about I call you?

Fan: [Jonghyun] You’re really going to sing for me?? Can I look forward to it?JongHyun: Yup, Look forward to it!

Fan: [Jonghyun] What is NUABO?!?!JongHyun: Because nuna is pretty so oppa is angry( In Korean, the first word in nuna is NU, the first word in pretty sounds similar to A while the first word in angry is B and oppa is O )

mE

supposedly i write bout me in


majority. Fifty-five percent of rhizobia isolates in this study formed colonies on YEMA media within three days of incubation and were therefore classified as fast growers according to Odee et al. \[[@B30]\]. The colonies formed by these fast-growing isolates in the present study were yellow with creamy margins, convex, round with entire margins of size ranging from 2 to 5 mm. Isolates of rhizobia forming colonies within 72 hours have been reported by Singh et al. \[[@B31]\] on soybean and Ngakou et al. \[[@B32]\] on Bambara groundnut, cowpea, and soybean. Slow-growing isolates formed colonies after 7--10 days of incubation that were small to medium sized, white or milky, and translucent and were raised with smooth margins. These are characteristics of*Bradyrhizobium*spp. as described by Howieson and Dilworth \[[@B26]\]. Sanginga etindicates that cowpea can form symbiotic associations with bacteria harbouring different culture characteristics. These results concur with those of Zilli et al. \[[@B19]\] who reported slow-growing strains of rhizobia that were acid producers. Both fast- and slow-growing isolates showed mucus production that ranged from high to intermediate with some isolates being dense and elastic and others diffuse and nonelastic. Mucus production probably represents a mechanism of rhizobia adaptation and endurance in hostile climatic and edaphic conditions. It prevents desiccation of the bacteria and helps them withstand fluctuations in temperature, salinity, and acidity \[[@B40]\]. Batista et al. \[[@B41]\] noted increased production of mucus in isolates of*Bradyrhizobium*as a mechanism of adaptation to acid soils of Cerrado region in Brazil. Mucus production by most rhizobia isolates is a fundamental characteristic that


significant because it suggests the university was warned about Sandusky, in no uncertain terms, as early as 1998, but did not stop the alleged abuse.

Sandusky, a longtime defensive coordinator for the Nittany Lions, is currently under house arrest as he awaits trial on more than 50 counts of child sexual abuse. He has pleaded not guilty.

Former school officials Tim Curley and Gary Schultz are charged with perjury and failure to report a crime in relation to the investigation.

In addition to Chambers’ evaluation, NBC News released a 1998 campus police report tied to the same sexual misconduct allegations against Sandusky. It described a second evaluation conducted by John Seasock, identified as another psychologist.

Like Chambers, he spoke to the child in question about what transpired between him and Sandusky. Hewere dead.”

No charges were ever filed in that instance, and local and state law enforcement authorities did not look deeper into those and other allegations against Sandusky until years later.

Howard Janet, attorney for Victim 6, released a statement soon after news of the report broke on Saturday, blasting Penn State for failing to take action.

“Why was a second opinion sought from someone with a connection to Jerry Sandusky? Why were reports of inappropriate contact between Sandusky and young boys on the Penn State campus and Penn state activities consistently ignored?”

“Much of the evidence coming to light points to a conspiracy of silence surrounding Sandusky’s behavior at the expense of children,” he wrote.


fall apart this year and has delivered one of the most miserable seasons at Stamford Bridge in recent memory. It’s got so bad that we even feel a slim slither of sympathy for Chelsea fans.

Then we remember that train incident in Paris. Never mind.

This season in isolation, without the slightest hint of an unjust personal vendetta, gives us reason alone to hurl abuse at our TV screens and hoist up the Red Devil and weird, broken-necked, fire-breathing lion who’s eating its own tail whilst holding a bubble wand kind of effigies.

When you add things like Stamford Bridge’s on-site hotels, United supposedly being supported by almost one in eleven people alive and players such as Jesse Lingard and the rest of the Dabtastic Krazy Krew, you concoct an eventhese lower-molecular-weight ET-AR transcripts may result from alternative RNA splicing. Therefore, we isolated the cDNAs of novel transcripts of hET-AR that might be generated by alternative RNA splicing. These results suggest that the alternative RNA splicing might contribute to the regulation of ET-AR gene expression.


function colorscale = CBIG_GenerateHSVColorscale(res, min_val, max_val, output_dir)

% colorscale = CBIG_GenerateHSVColorscale(res, min_val, max_val, output_dir)
%
% Produce a discretized colorscale based on Matlab's HSV color scheme
%
% Input:
%   - res       : number of discrete values in the colorscale
%   - min_val   : minimum of the colorscale
%   - max_val   : maximum of the colorscale
%   - output_dir: output directory of the colorscale's image
% Output:
%   - colorscale: colorscale in Matlab's format with res number of values discretized from the HSV color scheme
%
% colorscale = CBIG_GenerateHSVColorscale(28, 5e-5, 1, ...
%   '/Work/data/colorscale')
%   Generate a discrete colorscale of 28 bins with the value ranging from
%   5e-5 to 1. The colors come from thethe
   * exception of the logic to find the actual start of the ECD64.
   * ECD64Locator contains only its position in the file, which is off by
   * preamble size, but does not contain the actual size of ECD64, which in
   * theory is variable (the fixed fields may be followed by some custom data,
   * with the total size saved in ECD64::remaining_size and thus unavailable
   * until we find ECD64.  We assume that the custom data is missing.
   */

  // First, sanity checks.
  uint32_t cen_position = ecd->cen_offset32();
  if (!ziph::zfield_has_ext64(cen_position)) {
    if (!mapped_file_.mapped(mapped_file_.address(cen_position))) {
      diag_warnx("%s:%d: %s is corrupt: Central Directory location 0x%"


         ecd64->cen_size());
      preamble_size_ = mapped_file_.offset(cdh_) - ecd64->cen_offset();
      // Find CEN and preamble size.
    } else {
      if (ziph::zfield_has_ext64(cen_size) ||
          ziph::zfield_has_ext64(cen_position)) {
        diag_warnx(
            "%s:%d: %s is corrupt, expected ECD64 locator record at "
            "offset 0x%" PRIx64 " is missing",
            __FILE__, __LINE__, path.c_str(), mapped_file_.offset(ecd64loc));
        return false;
  can access the Big Branch Trail, a streuous, 2-mile loop known for its small waterfalls, wildflowers and old farmsteads.

The National Park Service opened the Sandstone Visitor Center in 2003 in the hamlet of Sandstone.

The facility focuses on the New River watershed, its natural and cultural history and its activities over the years including timbering and coal mining.

It offers educational exhibits on the park, its resources and its heritage.

Hours: 9 a.m. to 5 p.m. daily except a few holidays.

For information, call 304-466-0417.

Nearby Hinton, once a major rail town on the New River, has its own historic district that is on the National Register of Historic Places. A walking tour of the downtown area is available.


initial charged particles are hadrons.

After rejection of one-prong decays containing muons and electrons the following exclusive and semi-exclusive $\tau$ decay modes have been isolated and their branching ratios measured:

-   Charged multiplicity one:\
    $h^- \nu_\tau$,    $h^- \pi^0 \nu_\tau$,    $h^- 2\pi^0 \nu_\tau$,     $h^- \geq 3\pi^0 \nu_\tau$;

-   Charged multiplicity three:\
    $2h^-h^+ \nu_\tau$,     $2h^-h^+ \pi^0 \nu_\tau$,     $2h^-h^+ \geq 2 \pi^0 \nu_\tau$;

-   Charged multiplicity five:\
    $3h^-2h^+ \nu_\tau$,     $3h^-2h^+ \geq 1 \pi^0 \nu_\tau$.

where $h$ is either a $\pi$ or $K$ meson. The charge conjugate decays were also included.

The $\pi^0$ mesons were detected and reconstructed via the photons produced in the decay $\pi^0\to\gamma\gamma$. This $\pi^0$ decay mode has a branching ratio of (98.798$\pm$0.032)%, the remainder decayingthis led to three additional classes, corresponding to those decays which were unclassified. Having three classes instead of just one for all the unclassified modes, does not improve the precision on the measurement, but gives additional information on the comparison of topological and exclusive branching ratios.

If we do not take into account these three extra classes, the problem is undetermined, since there are $n_c+1$ unknowns (the $n_c$ branching ratios and $N_\tau$) and only $n_c$ measurements. The inclusion of these three classes, corresponding to the events not assigned to any given class, does not help, because, despite having three additional measurements, the equations are nearly degenerate (the matrix is almost singular) and the resulting fit is highly unstable. We avoid the problem by setting an additional constraint that all


variable, where the fake photons rate is comparable to that of the real photons. The simulation was found to reproduce correctly the data to a relative $3$%.

### Energy scale {#sec:eemphot}

In addition to the previously measured electron samples, the HPC energy scale was studied using isolated photons in $\mm\gamma$ and $\ee\gamma$ final states and $e\gamma$ compton scattering events. In these three cases the direction is well defined and the particle energy can be inferred with a very good precision using kinematic constraints, independently from the energy measurement in the calorimeter. This allowed the HPC energy response to be calibrated as a function of energy. A precision of 0.5% or better was obtained on the energy scale throughout the entire energy spectrum. The measured energy resolution was $\sigma(E)/E = 0.31at least one charged particle in each hemisphere.

Hadronic decays of the Z were suppressed by requiring that there be a maximum of eight charged particles in an event. Background from four-fermion events was reduced, together with a further suppression of Z hadronic decays, by requiring that the event isolation angle be greater than $160^\circ$. The isolation angle was defined as the minimum angle between any pair of charged particles which were associated to opposite $\tau$-decay hemispheres. Backgrounds from $\mm$ and $\ee$ final states and cosmic rays were reduced by requiring that the isolation angle be less than $179.5^\circ$ for events with only two charged particles.

The $\mm$ and $\ee$ contamination was reduced further by requiring that both and be less than unity. The variables $\vec{p}_1$ and $\vec{p}_2$ are the


              0.00 0.10     17.26 1.18     23.08 1.31      0.00 0.10      2.20 0.46
  $\pi^-3\pio{\nu_{\tau}}$                            0.02 0.01     10.65 0.25     41.23 0.40      0.05 0.02      2.16 0.12
  ${2\pi^-\pi^+ {\nu_{\tau}}}$                        0.02 0.00 0.02 0.00      1.32 0.02      0.51 0.01      0.16 0.01      0.01 0.00
  ${\mu^- {\nu_{\tau}}\bar{\nu}_{\mu}}$               0.10 0.01     88.02 0.07      2.50 0.03      0.41 0.01      0.01 0.00      0.00 0.00
  $\pi^- {\nu_{\tau}}$                                2.07 0.04      1.80 0.04


mode for all decays are shown in Figs. \[fig:neuronop1\] and  \[fig:neuronop2\]. In most cases, this shows satisfactory agreement between data and simulation.

### Three-prong decays {#sec:nn_threeprong}

The three-prong $\tau$-decay candidates selected were divided into three classes: $2h^-h^+ \nu_\tau$, $2h^-h^+ \pi^0 \nu_\tau$ and $2h^-h^+ \geq 2 \pi^0 \nu_\tau$.

A simpler network was used in this case, with all the electron/muon/hadron-identification variables removed and the remaining variables kept, giving a total of seven variables:

-   the total momentum of the charged-particle system;

-   the total electromagnetic energy associated to the charged-particle tracks;

-   the total electromagnetic energy deposited in a cone of half-angle 15$^\circ$ around the momentum vector of the charged-particle system including that associated to the charged-particle tracks;

-   the number of reconstructed photons;

-   the number oftotal $\chi^2$, computed with statistical errors only. In parenthesis is shown the number of data points used in each case. The last three lines compare the measured number of unclassified events with the expectation after the fit.*[]{data-label="tab:nn_res"}

The invariant-mass distributions of the different classes of selected decays are shown in Figs. \[fig:nninvmass\] and  \[fig:nninvmass2\].

Systematics {#sec:systematics}
===========

The systematic uncertainties due to any specific source were estimated simultaneously for all measured decay modes in the neural-network and sequential-cuts analyses. This was also the case for inclusive branching ratios, where the calculated systematic errors accounted for the existing cancellations between the errors of the different channels involved, leading in many cases to smaller errors. The systematic errors were evaluated using test samples of events as discussed in Sections \[sec:chargedparticles\] and \[sec:photons\]. Where appropriate the relevant input variables were


regions far from the cut, and where the signal and background separation was very clear and therefore did not affect the results significantly compared to the quoted systematic errors. In particular, the largest contribution, arising from the ${{\tau^- \rightarrow}{\mu^- {\nu_{\tau}}\bar{\nu}_{\mu}}}$ channel is due to the slight widening of the sharp peak on the neural network output distribution (Fig. \[fig:neuronop1\]) caused by the HCAL and muon chamber response systematics, with a migration of a small fraction of events from values close to 1 to the region from 0.5 to 1. This has a large impact on the $\chi^2$, but very small one on the results, since they are nevertheless identified clearly. Similar arguments apply to the second largest contribution, from the ${{\tau^- \rightarrow}{2h^-h^+ {\nu_{\tau}}}}$, but in this case the neuralmethods utilizing while blood cells [@bib11] and a feeder-free culture system [@bib12] have been established for use in medical treatment. The construction of medical iPS cells stocks was discussed among the Ministry of Health, Labour and Welfare (MHLW) [@bib26], CiRA, and the Japanese Red Cross Society, and these organizations have begun to cooperate in its construction. For transplantation of an organ or tissue, it is necessary to at least partially match the human leukocyte antigen (HLA) between the donor and recipient to reduce the incidence of graft rejection; three loci, HLA-A, -B, and DR, are important for this process [@bib27], [@bib28]. Okita et al. estimated that the establishment of 140 HLA-homozygous lines for iPS cells selected from 160,000 individuals would provide a match for 90% of the Japanese population


was no significant difference in those who answered "for anyone" between males and females. Participants who answered "person whom the hospital and specialized agency chose" increased in an age-dependent manner (p \< 0.001). These findings suggest that regarding organ or tissue donation for regenerative medicine, students focused more on the characteristics of the donors.Table 4Role as a recipient and donor in regenerative medicine (%).Table 4Sex (n)Junior high schoolHigh schoolUniversitySexTotal (2396)pMale (374)Female (350)Total (724)Male (311)Female (555)Total (866)Male (280)Female (526)Total (806)Male (967)Female (1429)**As recipient**I would receive an organ (tissue) prepared from my cells.54.870.062.246.067.259.646.468.861.049.568.560.9\*\*\*I would receive an organ (tissue) prepared from cells from my family.48.467.457.641.264.756.245.766.559.345.466.057.7\*\*\*I would receive an organ (tissue) prepared from cells from my friend.25.924.625.321.228.125.625.425.925.724.326.425.5I would receive an organ (tissue) prepared from cells of a person whom the hospital and specialized agencies chose.34.830.932.934.441.338.843.943.243.437.339.438.6\#\#\#I wouldfamily (p \< 0.001)" more than males. The proportion of participants who disagreed with cryopreservation of their own cells was 11.6%. The proportion of participants who wanted to stock cells for people whom the hospital and specialized agencies chose significantly increased in an age-dependent manner (p \< 0.001). Furthermore, regarding use of cryopreserved cells as a medical resource, the proportions of participants who answered "I want to stock my cells for the people whom the hospital and specialized agencies chose" and "I want to stock my cells for everyone" were 19.3% (n = 463) and 34.0% (n = 814), respectively. Because 148 participants answered "yes" to both cases, the total number of participants answering "yes" to either option was 1129 (47.1%). These results reveal that approximately 90% of students had a positive view on the storage


of the participants, respectively. Taken together, 73.9% thought that education was necessary. There was significant difference between males and females (p \< 0.001) and kinds of schools (p \< 0.001). The necessary of education for the public increased in an age-dependent manner (p \< 0.001). On the other hand, 75.6% of participants wanted to receive education for improving their understanding of iPS cells and regenerative medicine ([Fig. 6](#fig6){ref-type="fig"}B). Females wanted to undergo the education than males (p \< 0.001), and it increased in an age-dependent manner (p \< 0.001). Thus, more than 70% of students supported education for the understanding of iPS cells and regenerative medicine.Fig. 6Need of education of iPS cells and regenerative medicine. (A). Q18. Do you think that education for the understanding of iPS cells and regenerative medicine is necessary for the public? Statistical significance: p \< 0.001 vs.(a) 32  (b) 0.5  (c) 4  (d) -1013
a
Which is the second biggest value?  (a) 113/3  (b) -0.1  (c) 1/3  (d) -0.2  (e) -1/11
c
Which is the biggest value?  (a) 0.4  (b) -3/4  (c) -0.2  (d) -12  (e) -191  (f) 5
f
Which is the fourth biggest value?  (a) 0.9  (b) 1  (c) -143  (d) -3/7
c
Which is the fifth smallest value?  (a) -10  (b) 2/11  (c) -1  (d) 3  (e) 2/5  (f) -3/8
e
Which is the smallest value?  (a) 6  (b) 1490  (c) -1.6
c
Which is the second biggest value?  (a) 0.001  (b) -0.4  (c) 5  (d) 1/3  (e) -0.081
d
What is the


 (a) -0.19  (b) 3  (c) -3  (d) 104
c
Which is the fourth biggest value?  (a) 3/2  (b) 2  (c) -0.8  (d) -2  (e) -0.18
c
Which is the second biggest value?  (a) 454  (b) 0.2  (c) 866
a
Which is the second biggest value?  (a) -3/5  (b) -10/9  (c) 5/111  (d) 21
c
Which is the biggest value?  (a) 5  (b) -31  (c) 215
c
Which is the fourth biggest value?  (a) 4  (b) -64  (c) -2/23  (d) -0.42
b
What is the biggest value in 2/9, -0.1, -2/2837, 3, -5, -0.4?
3
What is the biggest value in 0, -4, -1/643, -12?
0
What is the fourth smallest value in -1/2, -1/5, 3, 204?
204
Which is the third smallest value?Surviving adults were further investigated. Insecticide-treated RE adults with LC1 and LC10 of cypermethrin showed significantly slower onset of predation averaged 14.20 and 18.35 h, lower number of preys killed, averaged 4.8 and 4.2 larvae/d, respectively, as compared to those of untreated ones. The corresponding figures of treated adults with deltamethrin were 30.5 and 42.2 h, 4.6 and 3.8 larvae/d respectively. Similar results were obtained on RE adults that fed on insecticide-treated 3rd instar SSB larvae with the same concentrations of insecticides. The only different result was recorded on the number of preys killed by indirectly treated adults with LC1 of cypermethrin and deltamethrin averaged 9.6 and 8.8 larvae/d, respectively, which was not significantly different as compared to those of untreated ones. Insecticide-treated RE adults with LC10 of


Q:

Why the application crashes when I add methods to run audio using MediaPlayer Class?

I've added an mp3 file to the resource "raw" directory in order to have a button that plays the audio file and another one that pauses it, but when I try to run it, it crashes
This is the MainAcitvity class file:-
package com.sefonia.mediaplayer;

import androidx.appcompat.app.AppCompatActivity;

import android.media.MediaPlayer;
import android.os.Bundle;
import android.view.View;

public class MainActivity extends AppCompatActivity {

    @Override
    protected void onCreate(Bundle savedInstanceState) {
        super.onCreate(savedInstanceState);
        setContentView(R.layout.activity_main);
    }

    // Define the Media file player with MediaPlayer Object
    MediaPlayer mediaPlayer= MediaPlayer.create(MainActivity.this,R.raw.mine);

    /**
     * Starts playing the music

Man tracks stolen laptop hundreds of miles away, calls thief - ChrisArchitect
http://storify.com/btballenger/man-tracks-stolen-laptop-thousands-of-miles-away

======
ChrisArchitect
the perceived risks taken by locals in this story, and the way this plays out
in the 'storify' flow is great. That Prey company should have some 'emergency'
guidelines for how to track and get back your laptop. Like -- what is the best
way to approach law enforcement, instead of vigilante tactics. heh

~~~
nantes
How about a way to automatically file a police report?

~~~
ktsmith
You'll find that in most cases you have to be physically present to file a
police report as was the case in this story.


was 1) saturable with a Vmax value of 19.78 and 6.24 nmol/g tissue/5 min and an apparent Km value of 16.20 and 8.19 microM, respectively, 2) not affected by metabolic inhibitors, and 3) partially temperature dependent (Q10 = 2.51 and 1.92, respectively). The structural analogues retinal (50 microM) and retinoic acid (50 microM) did not affect the uptake of [3H] retinol (0.06 microM) whereas unlabeled retinol (50 microM) caused significant (p less than 0.01) inhibition. No difference in retinol metabolism by intestinal tissue was observed in the two age groups. These results demonstrate that retinol uptake in suckling rats is similar to that of adult rats in being a passive carrier-mediated process. The results also suggest that a decrease in the number and/or activity and an increase incatchphrases made famous by Barack Obama and Hillary Clinton — "You didn't build that" and "It takes a village."

Obama's 2012 message to business founders, "You didn't build that; somebody else made that happen," shaped the Republican counterattack in Summer 2012. "I DID build that," team Romney cried, again and again.

But in its full context, "you didn't build that" is true. Obama's line began this way: "If you were successful, somebody along the line gave you some help. There was a great teacher somewhere in your life. Somebody helped to create this unbelievable American system that we have that allowed you to thrive ..."

This is actually something conservatives frequently celebrate. Entrepreneurs often need investors and they always need customers.

Also, consider what economists call "complimentary goods": Steve Jobs' iPhone wouldn't


be worth as much without Twitter, Yelp, or Google maps. The high-resolution camera is a major selling point of the iPhone 5, and Sony makes the camera — Steve Jobs didn't build that.

H.J. Heinz's ketchup couldn't have dominated the country 100 years ago if other businessmen (and governments) hadn't improved shipping, refrigeration, and bottling. Free-marketeers celebrate the dynamic interconnectedness of the marketplace.

More importantly, when those entrepreneurs were young they needed parents and a family — and a community where they could learn and grow.

So why did conservatives so hate "You didn't build that"? Why did this drive the right to the Ayn Rand hymnal?

Because they feared Obama meant something else — something threatening to liberty. After all, "You didn't build that" was Obama's justification for more taxes, regulations,I'm not that surprised. There are written accounts from Gaul of druids using mistletoe to treat a number of ailments, including some with symptoms similar to some abdominal cancers. I can't remember if it was Pliny or Agrippa who wrote of it being used to cure stomach/bowel pain "that brings on death".

Jgok:I'm not that surprised. There are written accounts from Gaul of druids using mistletoe to treat a number of ailments, including some with symptoms similar to some abdominal cancers. I can't remember if it was Pliny or Agrippa who wrote of it being used to cure stomach/bowel pain "that brings on death".

And he advised sticking bread in your ears. To cure headaches IIRC. So we know we should take his comments on medicine serious.

Kyosuke:tennessee.hillbilly:Then again, it probably


centuries ago... you just have to sift through the crap to find the good stuff.

I actually enjoy reading through that stuff and trying to find the nugget of truth behind all the traveler's tales that they recorded. I've been reading through Agrippa's "Three Books of Occult Philosophy" lately, and there are some crazy bits in there... especially in the first book's section on plants and animals that exist under the influence of planetary bodies/astrological signs. It's mostly over-exaggerated BS, of course, but it's interesting to read through, and some of the medicinal plants listed are still being used today.results support the idea that a BCG and its host cluster coevolve.

As shown in @lee17, the pCMD backbone analysis is a useful method for comparing the formation histories of galaxies even with different mass or size scales, but it needs to be more simplified to be efficiently applied to a large number of galaxies. One of the remarkable quantities is the color dispersion at given $\mu_r$ in a pCMD. This quantity is thought to reflect the complexity of stellar populations. That is, a dynamically young galaxy, in which multiple stellar populations are not well mixed spatially, must have large color dispersion. Based on this inference, @lee17 concluded that the BCG of A1139 is dynamically younger than the BCG of A2589. However, since BCGs usually have simple structures, it


target galaxy, whereas the masking is conducted when it is unclear whether the target is over-masked or not. At least among our sample galaxies, there was rarely ambiguous situation and thus we decided the final masking sets relatively at ease.

However, the adaptive masking has a fundamental weakness: late-type galaxies with complicated structures tend to be masked too little, compared to early-type galaxies with simple structures. Because late-type galaxies are expected to have remaining contaminants that were not sufficiently masked in the SE-detection-based masking process, a supplementary masking process is necessary. For this, we additionally masked the pixels that correspond to the pCMD outliers. The processes are listed as follows:

1.  Estimate the 5, 50, and 95 percentiles in the pixel $g-r$ color distribution at given $\mu_r$, using theOn the other hand, the full masking processes were applied to every elliptical galaxy. That is, the masking processes for early- and late-type galaxies are not identical in the standard procedure, and thus the comparison of the final pCMDs between galaxies with different morphological types may not be fair.

To address this issue, we try an alternative masking procedure that does not depend on subjective ‘adaptation’ according to galaxy morphology. This procedure is based on the idea that the light from contaminants tends to be brighter than the brightness expected at the distance from the target galaxy center. The detailed procedure is as follows:

1.  Trim a sufficient area around a target galaxy,

2.  Trim the image again with a radius of $f_c\times R80_{(22.2-23.2)}$, where $f_c$ is a fixed


face-on S0 galaxy in our sample (A1139-00002) shows a blue pCMD-tip feature, which indicates that this galaxy may have experienced central star formation activity very recently.

The (barred and unbarred) spiral galaxies show complex and diverse features in their pCMDs. The pCMD structures of a spiral galaxy is roughly described to consist of a (red and bright) bulge part and a (blue and faint) disk part, which form an overall inverse-L feature. However, whereas this division is quite clear in some spiral galaxies (A1139-00016, A2589-0004 and A2589-00011), some other spiral galaxies show more complicated and amorphous features (A1139-00017 and A2589-00015). The bulge-dominated spiral galaxies (A1139-00008, A1139-00009 and A2589-00007) show relatively simple pCMD features compared to the other spiral galaxies, but more distorted than the pCMDs of typical elliptical galaxies.

Finally,of stellar populations in those galaxies may not necessarily originate from merger events, but it may be naturally caused by recent star formation not from merger origins. Even in that case, however, the recent star formation must have been spatially not uniform at scales larger than 600 pc ($\sim0.8''$ in our images) to enlarge the color dispersion in a pCMD. It may require anisotropic infall of gas. Gas interactions without disturbance of stellar orbits can be such an origin, which may happen even for cluster galaxies with high encounter velocities [@par09]. Although the exact origin of the recent star formation cannot be determined in this paper, it is plausible that some environmental effects acted on the large color dispersion in a pCMD.

The interpretation of the max($g-r$)$_{\mu_r\le23.2}$ versus \[4.6\]


$-$ \[12\] plot (Figure \[wise1\](b)) is somewhat complicated (Figure \[wise1\](b)). At first glance, the data points seem to be randomly scattered in this plot. However, as shown in Table \[wisecc\], we find two opposite trends when we inspect the sub-samples of the elliptical + disky elliptical galaxies and the spiral galaxies: (1) the elliptical galaxies with infrared-color excess tend to have redder maximum pCMD color, but (2) on the other hand, the spiral galaxies are getting bluer in the optical band as infrared color increases.

These two opposite trends imply that multiple physical origins may be involved in the max($g-r$)$_{\mu_r\le23.2}$ versus \[4.6\] $-$ \[12\] relation. For example, the marginal correlation of elliptical + disky elliptical galaxies may result from dust remnants in some elliptical galaxies. That is, elliptical galaxies that have recentlyexperienced star formation may have remaining dust, which cause red infrared color (due to remaining warm dust) and red optical color (by dust extinction) at the same time. On the other hand, spiral galaxies with redder infrared color may have more active current star formation unlike elliptical galaxies, and thus they tend to have blue optical color due to a large amount of young stars that cannot be sufficiently obscured by dust. It will be worth checking if these trends are established still in a sufficiently large sample of galaxies in future studies.

CONCLUSION
==========

We analyzed the pixel color-magnitude diagrams (pCMDs) of 32 bright galaxies in two galaxy clusters A1139 and A2589 at low redshifts. We yielded the pCMDs of the sample galaxies using the SE-detection-based masking or the $R(\mu_r)$-based


Shona McIsaac

Shona McIsaac (born 3 April 1960) is a British Labour Party politician. She was the Member of Parliament (MP) for Cleethorpes from 1997 to 2010. She was defeated by Conservative candidate Martin Vickers in the 2010 election.

Before politics
She went to the SHAPE High School in Mons in Belgium, then Barne Barton Secondary Modern school in St Budeaux and Stoke Damerel High School for Girls in Stoke, Plymouth, which closed in 1986. She studied for a BSc in Geography whilst at St. Aidan's College of University of Durham, being taught by David Bellamy, and graduated in 1981.

She wrote and worked on women's weekly magazines, being deputy chief sub-editor of Bella, senior sub-editor of Chat and chief sub-editor of Woman.

Parliament
McIsaac started her political career as a councillor to the One effect of these rules is that -bareword is equivalent to the string "-bareword".

This behavior of the unary minus operator is applied to the bareword before the strict checks are applied. Therefore, unary minus is a kind of quoting operator that also works in strict mode.
Similarly, barewords as the invocant in method invocation do not need to be quoted as long as they are not a function call:
Foo->bar;    # 'Foo'->bar(); --- but only if no sub Foo exists
print->bar;  # print($_)->bar();

However, the unary minus behaviour seems to be due to constant folding, not due to a special case in the parser. For example, this code
use strict;
0 ? foo : bar;

will only complain about the bareword "bar" being disallowed, suggesting that the bareword check happens


change supervisor. That being said, depending on what you mean with 'preliminary results', this seems far from obvious to me.

Another query is, is it ethical to collaborate with people outside the university (of course after letting my supervisor know) for my PhD work. My Masters supervisor would be happy to help me out.

Ethical? Sure - but that does not mean that your supervisor needs to be happy about it or let you do it if (s)he perceives that your main work suffers from it. Look around on this site on the topic of side projects - this has been discussed a number of times here.

identified to date. To further complicate matters, the solvent or medium in which the absorber is formulated will affect its absorbtion spectrum. While these shifts in absorbtion spectra can be qualitatively estimated, to some extent sunscreen formulation is an empirical art.
On the other hand, dermatologists have been resorting to the use of UVA and UVB radiation for the treatment of various skin conditions. UVB has been used for treating acne for some time. More recently, UVA radiation has been used for treating various dermatological fibrotic conditions: M. C. Polderman et al., “Ultraviolet A-I phototherapy for skin diseases,” Ned Tijdschr Geneeskd, 1999 May 1, 143(18):931-4; M. El-Mofty et al., “Low-dose broad-band UVA in morphea using a new method for evaluation,” Photodermatol Photoimmunol Photomed 2000 Apr. 16(2):43-9; J. Dutz, “Treatment


wishing to improve local allergy service provision.

I am personally indebted to the Chairpersons, all of the members of the Committees, and the WAO staff for the outstanding work they did.

Education {#s1-2}
---------

WAO continued its educational outreach globally with its Global Resources In Allergy and Immunology (GLORIA). International placements were hosted in Singapore, the Philippines, Georgia, Honduras, India, Dubai, and Bangladesh. In the United States, in association with the American College of Allergy, Asthma and Immunology, 25 placements were hosted at regional and local allergy society meetings. Also successful were WAO seminars and conferences, which supported invited lecturers in South Africa, Mongolia, Argentina, the United Arab Emirates, and Italy. Four successful "World Allergy Forum" symposia were held at the annual meeting of the American Academy of Allergy Asthma and Immunologyand a poster on the emergency management of anaphylaxis for display in European Emergency Rooms.WAO representatives attended the 2008 EAACI/GA^2^LEN Urticaria guidelines meeting, expanding the output to a global recommendation.WAO and Genetic and Rare Diseases Information Center (GARD) collaborated on a global survey of allergy diagnostic methods, preparatory to the development of inexpensive allergy diagnostic tools.Interasma hosted the winter 2008 WAO Board meeting; WAO experts contributed to the Interasma scientific program.The WAO sublingual immunotherapy meetings brought together many international scientific organizations.WAO agreed with the International Primary Care Respiratory Group to develop an immunotherapy document for general practitioners.

INITIATIVE 3. EXPLOIT WEB TECHNOLOGY AND THE WAO WEB SITE: "WE SHOULD REACH EVERY ALLERGIST IN THE WORLD" {#s3}
=========================================================================================================

WAO is indebted first to Richard Lockey, Juan Carlos Ivancevich, and the WAO staff


with the first comprehensive Web-based learning activity on food allergy in 2008, followed by the second module on Drug Allergy in 2009. The library of educational synopses in the Allergic Diseases Resource Center grew to more than 40 concise overviews, all peer reviewed, on clinical allergy topics for practicing allergists and immunologists.

Distance learning was launched with the successful hosting by the WAO also of 3 live lectures or webinars. Speakers gave lectures from the University of South Florida, US, as their audiences watched, listened, and interacted from the Highlights in Allergy and Respiratory Disease Conference, Genoa, Italy, the World Congress on Asthma, Monaco, and the first Middle East-Asia Allergy, Asthma, Immunology Congress (in Dubai). Those historical lectures are archived on the WAO Web site ([www.worldallergy.org/educational_programs/webinars.php](www.worldallergy.org/educational_programs/webinars.php)).

INITIATIVE 4. EMPOWER THEbinding operator recognize $a but do not return my desired sequence (with ID stored in $a), instead it returns the very first sequence.
The result I expect is:
'>' SCO0755, putative ABC transporter 797720:799942 forward MW:79858
VSTAQETRGRRRAAPPRRSVPKSRARTVRTPTVLQMEAVECGAASLAMVLGHYGRHVPLE
ELRIACGVSRDGSRASNLLKAARSYGFTAKGMQMDLAALAEVTAPAILFWEFNHYVVYDG
'>' SCO1144, putative ABC transporter ATP-binding protein 1202480:1204282 reverse MW:64637
MHPDRESAWTAPADAVEQPRQVRRILKLFRPYRGRLAVVGLLVGAASLVSVATPFLLKEI
LDVAIPEGRTGLLSLLALGMIFGAVLTSVFGVLQTLISTTVGQRVMHDLRTAVYGRLQQM

A:

First, don't use $a and $b in your code.  They're special variables that only make sense within a sort block; avoid them elsewhere, use meaningful variable names instead.
Secondly,
my @PID = '<'PID'>';

Assuming you're trying to read the contents of the filehandle PID into an array, you mean:
my @PID = <PID>;

Thirdly, common best practice these days is to use 3-arg open and lexical filehandles, for instance:
open(my $pidfh, '<', 'PID.txt') or die "...";
my @PID = <$pidfh>;
close $pidfh;

Do you have use strict; at the top


in the next 20 years, which is considered to be high in comparison to developed regions. This rapid growth in air passenger traffic from Asia-Pacific is expected to lead to aircraft manufacturers in the region increasing their aircraft capacities by procuring new airplanes. This increased number of planes would require more adhesives, which is projected to drive the growth of the aerospace interior adhesives market.

In the process of determining and verifying the market size for several segments and subsegments gathered through secondary research, extensive primary interviews were conducted.

Research Coverage:
The report provides an analysis of the global aerospace interior adhesives market and its different segment across different industry verticals and regions. It aims at estimating the market size and future growth potential of this market across different segments suchAuthor: ChiefBrick

Life is full of ups and downs. Click, click, clicks and wizzy bits. Trying to fit everything into every day, every week or even every month is always challenging. Winter is right around the corner and I can’t believe summer and fall have passed by so quickly. My life has finally started to calm… Read more

I know the Brick Barn has been fairly silent lately as I get use to my new job (come say hi at Walmart). Hopefully, I will be able to add more hours as the weeks roll on this summer. For starters, I have two Sunday’s off in the next two weeks and I will… Read more

If you are planning a future visit to the Brick Barn please be advised it is now


Q:

What is the significance of Shasta soft drinks?

In the movie, Signs, there is a scene depicting an old man who is an owner of a book store complaining about soda commercials and the frequency that they are being aired.

It's just a bunch  of crock. They're trying to sell sodas.   It's
  plain and simple. Been watching these reports since morning. I have
  seen twelve soda commercials so far...twelve!

There is a commercial for Shasta soft drinks shown during this time.  The commercial is an ad from 1984. Signs is set in present day 2002, when the movie was released.
What is the significance of showing a commercial for Shasta soft drinks?  Shasta is not a brand of soft drink that is aspopular vote. Those laws were now in jeopardy as a result of the court's ruling, legal experts said. The decision on Tuesday, however, also raised the prospect that electors could legally defect at the last minute, and decide the occupant of the White House on their own in dramatic fashion, weeks after Election Day.

Leading House Dem slams 'Squad' members and Trump for allegedly spreading anti-Semitism

House Judiciary Chairman Jerry Nadler, D-N.Y., called out both his fellow Democrats, Reps. Ilhan Omar, D-Minn., and Rashida Tlaib, D-Mich, and President Trump on Thursday, claiming they helped further anti-Semitism in the nation's "political dialogue." "The growing anti-Semitism in our political dialogue is repugnant," Nadler said. He pointed to Trump's comments about "disloyalty" in Jews who voted for Democrats, as well as a cartoon


as 'nipple, breast, penis, scrotum and uterus.' And once they are promoted to first grade, children will learn that sexual relations could happen between two men or two women. By the time students are 10 years old, instruction will include the various ways people can have intercourse, be it vaginally, orally or through 'anal penetration.'"

What is at the heart of evil in our world, and how do we lessen its power in our own lives? Check out David Kupelian's newest book, "How Evil Works: Understanding and Overcoming the Destructive Forces That Are Transforming America"

First of all, since when do school nurses have the authority to teach anything? I don't even think my school nurse was an actual nurse. Check for lice, give them a cool towel for theirOssification of the posterior longitudinal ligament in non-Asians: demographic, clinical, and radiographic findings in 43 patients.
Ossification of the posterior longitudinal ligament (OPLL) is a disorder afflicting as many as 2% of East Asians. However, reports of OPLL in non-Asians have been sporadic in the medical literature. This study describes clinical and radiographic findings with OPLL in non-Asians at a tertiary care center treating a diverse multiethnic population. Over a 6-year period, 43 patients not of East Asian descent presented to an urban tertiary medical center with OPLL. Patient data, including ethnicity, spinal cord function, Nurick grade, radiographic findings, OPLL subtype, and degree of cervical stenosis, were recorded. The average patient age was 59 years (range 32-92 years) with 18 women and 25 men. There were 22 Caucasian patients,


17 Hispanic patients, and 4 Black patients. With respect to the radiographic findings, OPLL morphology was continuous in 19, segmental in 17, mixed in 6, and other in 1. Average canal diameter was 7.6 mm (range 4.2-9.0 mm) at the most stenotic points. The mean Nurick grade was 2.95 at presentation, but 7 of the patients had OPLL identified incidentally and with early or minimal symptoms and signs of myelopathy. Ossification of the posterior longitudinal ligament in non-Asians demonstrates similar demographic and radiographic characteristics as in East Asians. The representation of different ethnic groups mirrors the demographics of the medical center population in general, showing no specific predilection for particular ethnic groups. Surgical decompression in appropriately selected patients results in similar rates of improvement when compared with the As security the bank took a chattel mortgage on substantially all of Pawnee's equipment and an assignment of three coal leases.  Lamar Hawkins, president of Pawnee, personally guaranteed the loan, and three Chicago investors guaranteed the loan up to $700,000.  Pawnee Construction, a related corporation, signed the note as co-maker.  In 1976 the bank loaned Pawnee an additional $750,000 to provide working capital, to bring current the arrearage on the first loan and to pay for the equipment and construction costs of a cleaning plant.  As collateral the bank took a security interest in the cleaning plant and the lease of the real estate on which the plant was located, as well as mortgages on realty in Winston and Marion Counties, Alabama.

4
In early


$183,586.94 by three o'clock that afternoon.  On leaving the bank Barterline decided there was not enough time to investigate the purchase and decided against it.

6
During lunch Barterline and Pawnee representatives sat a few tables apart at a restaurant.  Simner (of Pawnee) talked to Barterline about the proposed sale.  Simner asked if Barterline would buy Pawnee if Barterline obtained an assignment of the bank's collateral position.  Interest was rekindled and negotiations continued.  Reports and lists were compiled, a contract was drawn up, and papers concluding the sale of Pawnee to Barterline were signed around six o'clock that evening.

7
A one-page letter agreement signed by Barterline, Birmingham Trust, and Pawnee allowed Barterline to assume the bank's collateral position.  It recited the principal of the twowas not intact.  The only evidence we can locate that the equipment was not intact was that a bulldozer and a crusher were missing,7 but this does not give appellant an action for misrepresentation.  Birmingham Trust never said these were part of the collateral, and the first time any Barterline representative could have known the two pieces were ever part of the collateral was when a list attached to the purchase agreement listed the two pieces of equipment, both pieces marked through and the words "insurance claim" beside the dozer.  Therefore, at the same time Barterline found out Pawnee might have owned the two pieces of equipment it also learned that the items were no longer part of the collateral, or at minimum had knowledge


think about her behavior and to determine whether she wanted to remain

employed with respondent.

       When appellant returned to work, she apologized for her behavior, and Cedarblade

indicated that if appellant had another outburst she would be terminated. But a few days

later, Cedarblade reprimanded appellant for using an e-cigarette at her workstation.

Appellant denied that she used the e-cigarette inside the office and instead claimed that

she just showed the e-cigarette to a patient. A week later, on July 10, 2013, Cedarblade

again confronted appellant, this time about a patient who had complained about her poor

telephone demeanor.

       Appellant was involved in yet another alleged outburst on July 29, 2013, when it

was alleged that she “slammed down [her] phone” after she perceivedthat a co-worker,

Kate Braun, remarked negatively about her. Appellant denied that her conduct

                                             3
constituted an outburst, but she admitted being upset with Braun. Later that day,

appellant had a conversation with another administrative assistant, Sarah Benson, in

which appellant expressed her displeasure with the fact that Benson, rather than

appellant, was training a new employee. Although appellant claimed that the

conversation was cordial, Benson reported to Cedarblade that appellant accused her of

trying to steal her job.

       Appellant was reprimanded for her behavior


                                          13
the legal theory of a lawsuit” (quotation omitted)). A review of the letters at issue

demonstrates that appellant sent two letters to respondent laying out a basis for a sexual

harassment/hostile work environment claim, stating that appellant has “authorized

[counsel] to commence litigation on her behalf,” and proposing a settlement sum “in

exchange” for “a release” of appellant’s claims. Respondent’s August 30 letter

responded to the allegations and disputed that appellant had a viable cause of action. The

letter also stated that respondent had a valid basis to terminate appellant’s behavior based

onresponses. The district court has wide discretion

to issue discovery orders and, absent a clear abuse of that discretion, its discovery orders

will not be disturbed. In re Comm’r of Pub. Safety, 735 N.W.2d 706, 711 (Minn. 2007).

       Appellant argues that the district court abused its discretion by denying her motion

to compel information concerning the identity of any patients in the reception area on

September 10, 2013, as well as the individual to whom she was speaking when the

                                             19
alleged outburst


V. PEABODY WESTERN COAL CO.                   7

investigation, the EEOC sued Peabody in federal district
court in Arizona in 2001. The EEOC alleged that Peabody’s
implementation of the tribal hiring preference provisions
constituted national origin discrimination forbidden by Title
VII.

    After the EEOC brought its Title VII claims, Peabody
moved for summary judgment. The district court granted the
motion on two grounds, holding that the suit presented a
nonjusticiable political question and that the Nation was a
necessary party for whom joinder was not feasible. Peabody
I, 214 F.R.D. at 560–61. We reversed, holding that the suit
did not present a political question and that Rule 19 joinder
was feasible, provided that the EEOC sought no affirmative
relief against the Nation.government’s special
trust obligation to the tribes as quasi-sovereign political
entities, tribal preferences are permissibly based on political
classifications. Means v. Navajo Nation, 432 F.3d 924, 932
(9th Cir. 2005); Kahawaiolaa v. Norton, 386 F.3d 1271, 1278
(9th Cir. 2004); see Mancari, 417 U.S. 535.

    For the reasons that follow, we hold that the tribal hiring
preferences in the Peabody leases are based on tribal
affiliation, a political classification. We also hold that Title
VII does not prohibit differential treatment based on this
political classification.

                   1. Statutory Framework

   We begin by reviewing the relevant provisions of the
IMLA and of Title VII.

        a. The Indian Mineral Leasing Act


Indians
over non-Indians.

    The EEOC issued a policy statement in 1988 in which it
concluded that Section 703(i) is limited to general Indian
hiring preferences and does not, in itself, authorize
preferential employment practices based on tribal
affiliation—a statement to which we have accorded
deference. See Dawavendewa I, 154 F.3d at 1121. But this
statement does not end the inquiry. That Section 703(i) does
not itself authorize or create an exemption for tribal hiring
preferences on or near Indian reservations does not dispose of
the question before us: whether Title VII’s prohibition against
national origin discrimination prohibits the tribal hiring
preferences in the mineral leases.

          2. Tribal Affiliation and National Origin

    The correspondence between tribal membership, on the
one hand, and national origin, on the other,forms of preferential treatment
of Indians are based on political classifications rather than
national origin. Id.; see infra Subsection III.A.3. We also
held, giving EEOC’s 1988 policy statement “due weight,”
that Section 703(i) did not authorize tribal hiring preferences.
Dawavendewa I, 154 F.3d at 1121–22.

    The EEOC contends that our analysis must begin and end
with Dawavendewa I. But four years later, in a second appeal
in that case, we limited the scope of what we had earlier
written. In Dawavendewa v. Salt River Project Agricultural
Improvement & Power District (Dawavendewa II), 276 F.3d
1150 (9th Cir. 2002), we heard an appeal from the district
court’s dismissal of a claim for failure to join the Nation as a
defendant under Rule 19. We affirmed. In doing so, we
specifically rejected the plaintiffs’ contention that we had
previously held that


PEABODY WESTERN COAL CO.                  25

viewed Title VII as a recalibration of its policy toward tribal
communities that had been articulated in its prior legislation.
Nor is there any suggestion that Congress viewed Title VII as
a specific disapproval of Interior’s longstanding and settled
practice of approving tribal hiring preferences in mineral
leases. Cf. Dames & Moore v. Regan, 453 U.S. 654, 686
(1981) (“[L]ong-continued practice, known to and acquiesced
in by Congress, would raise a presumption that the [action]
had been [taken] in pursuance of its consent.” (alterations in
original) (quoting United States v. Midwest Oil Co., 236 U.S.
459, 474 (1915)).

    We therefore conclude that Title VII does not reach the
tribal hiring preferences in the Peabody leasesloophole in the law until specifically banned in 2012. It was used in AKM copies chambered or modified for it. It was a popular cartridge because it was easy to modify AKMs to fire it but still fed from standard AK magazines. Saquib brand makes 44 bore ammunition.

The ammunition used in the Khyber Pass region is often underloaded, being made from a variety of powders or even old film (which contains nitrocellulose, a key component of smokeless powder); Khyber Pass Copy rifles cannot be expected to withstand the pressures generated by modern commercial ammunition. A few collectors have made extremely mild handloaded cartridges for their Khyber Pass rifles and fired them, at substantial personal risk.

The packaging and headstamps are often forged versions of quality foreign brands like GECO


University City Campus Clean-Up

Monday, August 26, 2013

12:00 AM-12:00 AM

University Facilities is coordinating the annual University General Clean-Up from Monday, Aug. 19, through Friday, Sept. 20. This is an opportunity for departments and offices to dispose of obsolete or broken equipment, furniture and other large, non-hazardous materials. To participate:

Identify items to be discarded.

Submit a WEB TMA work order request or call (215)
895-1700 to arrange for a pick-up of items to be discarded. (Some
oversized pieces of equipment and sensitive items may not qualify for the
University General Clean-Up and will require special handling for
disposal.)

Once University Facilities receives the work order request, the items will be removed.

Items being disposed from laboratories may not include hazardous waste or dangerous chemicals. For all laboratory hazardous waste, contact Environmental Safety & Health at (215) 895-5891or a chain.
It is the object of the present invention to provide a drive unit for a vehicle, which drive unit comprises at least one electric machine and has, in connection with a wheel suspension which ensures a high level of driving comfort, a compact design and small unsprung masses.


to form the small central canal of the spinal cord.  The alar plate and the basal plate are separated by the sulcus limitans.
Additionally, the floor plate also secretes netrins. The netrins act as chemoattractants to decussation of pain and temperature sensory neurons in the alar plate across the anterior white commissure, where they then ascend towards the thalamus. Following the closure of the caudal neuropore and formation of the brain's ventricles that contain the choroid plexus tissue, the central canal of the caudal spinal cord is filled with cerebrospinal fluid.

Earlier findings by Viktor Hamburger and Rita Levi-Montalcini in the chick embryo have been confirmed by more recent studies which have demonstrated that the elimination of neuronal cells by programmed cell death (PCD) is necessary for  -------
        result : int
            The compiler node index for the node represented by the
            current parent ast node.

        """
        return self.index_map[self.ancestor()]

class FirstPassBlockCompiler(BaseBlockCompiler):
    """ The first pass block compiler.

    This is a base class for the first pass compilers for the enamldef
    and template block definitions.

    """
    #: A mapping of auxiliary ast node -> compiler node index.
    aux_index_map = Typed(dict, ())

    def


in node.body:
            self.visit(item)

    def visit_TemplateInstBinding(self, node):
        # Grab the index of the parent node for later use.
        self.aux_index_map[node] = self.parent_index()

    def visit_Binding(self, node):
        # Grab the index of the parent node for later use.
        self.aux_index_map[node] = self.parent_index()

    def visit_ExBinding(self, node):
        # Grab the index of the parent node for later use.
        self.aux_index_map[node] = self.parent_index()

    def visit_AliasExpr(self, node):
      Urgent and Important

What should you do right now? Obviously the thing that has to get done right now. But how do you know what that is.. and then what?

I found this chart a little while back and immediately learned a ton about how I do things wrong.

I had never distinguished the ideas of urgent and important. They were jumbled up together in a tangled web of stress, but we can split them out fairly easily. Urgency has a sense of time while importance has a sense of value.

Two of these quadrants are also very obvious. Of course the top of my list should be the thing that both has a lot of value and has to be done right now. And the things on the bottom of my


an article will never change its category, although it may change its title, so they just keep the general topic, which is business and the unique identifier 24511283.
In the end, what I suggest you do, as it's by far the most scalable solution is to just generate the following format:
http://localhost/blog/permalink/unique-id

The format above lets you have unique identifiers, which are important for guaranteeing singularity, and permalinks for all the search engine friendly-ness! Now if the title of the article changes, display the updated title to the user on the page, but don't do anything to the permalink, so that your URLs never change.
By also using IDs in the URL, you know for sure that you can use a permalink multiple times, and your system will still scale correctly.

[Court of Appeals unable to review

domestic violence conviction when transcript not provided].

       {¶14} Appellant’s sole assignment of error is overruled.

                                    CONCLUSION

       {¶15} Appellant’s sole assignment of error is overruled and the judgment of the

Delaware Municipal Court is affirmed.

By: Delaney, P.J.,

Wise, John W. and

Baldwin, J., concur.