analysis was carried out as previously described using primers specific for sequences located within WPRE region of the vector to determine copy numbers \[[@B22]\]. The average copy number of the transgene in genomic DNA isolated from transduced K562 cells was determined using the ABI 7900 sequence detection system and TaqMan chemistries (Applied Biosystems, Foster City, CA). In all the real time PCR analysis a single-copy eGFP lentiviral transgene containing DNA sample from a clone of 293T cells were included as reference control.

Statistical analysis
--------------------

Analysis of variance and Tukey\'s studentized range test were used to determine the significance of the differences in HIV-1 *Gag*(p24) levels in the vector supernatants.

Competing interests
===================

The author(s) declare that they have no competing interests.

Authors\' contributions
=======================

NC and DC participated in the design of experiments, carried out somein terms of the existence of the Fe vacancies, which results in a nonmonotonic change of the anion height with S content [@21]. In Fig. 6(c), we plot $T_{\rm c}$ as a function of chalcogen height from the Fe layer for (Li$_{0.8}$Fe$_{0.2}$)OHFeSe$_{1-x}$S$_x$, which shows that the $T_{\rm c}$ is monotonically decreased with shrinking of the anion height from Fe layer, with no sudden change in slope at $h$=1.38 or 1.45 Å. This does not follow the previous -shape in FeSe-derived superconductors or the inverse -shape in FeAs-based superconductors, suggesting the existence of peculiar physics in the (Li$_{0.8}$Fe$_{0.2}$)OHFeSe$_{1-x}$S$_x$ system. In FeAs-based superconductors, it is also thought that the regular tetrahedron of FeAs$_4$ might favor higher $T_{\rm c}$ and this might hold in FeSe-derived superconductors. However, Fig. 6(d) shows that


10 = 0 for z.
5
Solve -4*p + 8*q - 4*q = -8, -q = 4*p - 18 for p.
4
Solve 0 = c - 205 + 210, 3*v = 2*c - 5 for v.
-5
Solve 4*f + 4 = -2*q - f, 3*q = -f - 6 for q.
-2
Solve -4*n + 6*n + 8 = l, -5*n + 3*l - 22 = 0 for n.
-2
Solve 0 = -4*z - 16, 26 = -4*c - 5*z + 2 for c.
-1
Solve 5*q = -3*w + 34, -2 = -4*q - w + 21 for q.
5
Solve -3*q = 5*a - 20, 4*a = -q + 3*a + 6 for q.
5
Solve -62*z + 13 = 2*m - 63*z, -3 = 3*m + 3*z for m.
4
Solve -4*n + 8 = -2*n + 3*l, -l -1\n2017-09-16 00:07:59        1\n2017-09-16 00:07:56        1\n2017-09-16 00:07:50        1\n2017-09-16 00:07:32        1\n2017-09-16 00:07:49        1\n2017-09-16 00:07:48        1\n2017-09-16 00:07:39        1\n2017-09-16 00:07:38        1\n2017-09-16 00:07:37        1\n2017-09-16 00:07:36        1\n2017-09-16 00:07:33        1\n2017-01-01 00:00:08        1\nName: purchase_date, Length: 16395300, dtype: int64')

distributed.scheduler - ERROR - Workers don't have promised key: ['inproc://192.168.1.2/1271/2'], ('value-counts-agg-ef7612c5460d97ec66a1f75a33de8c6d', 0)
NoneType: None
distributed.client - WARNING


they fellows lock down(KEEP IT GANGSTA)Keep a glock in they pocket blowin shots till they pray I'm in town(KEEP IT GANGSTA)And to the snitch that ratted on rich the streets got you 16 rounds(THAT AIN'T GANGSTA)But theres only one place for a gully rat, six feet under the ground(YOU SAY KEEP IT GANGSTA)I'm gon keep it gangsta(YOU SAY KEEP IT GANGSTA)La la la la, la la la la(YOU SAY KEEP IT GANGSTA)

[Big Jack] (Butch Cassidy)Pick it up, pick it up, pick it upYo, stop with the posinY'all ain't really holdinI'm about to open, a chapter of the OmenCasket, closin, bodies, frozenI've, been chosen, y'all forsakenAnte up, so the chains get takenFlash backs of the rock season in the makingAin't no more MC'n, ice is just gleaminAnd you wondermetric. Both uncountable cofinality and Cayley boundedness have been studied in the literature, though aparently mostly independently of eachother. Uncountable cofinality grew out of J.P. Serre’s work [@serre] on property (FA), which is a fixed point property for actions on trees, in which it proved to be one of the three conditions in his equivalent formulation of property (FA) for uncountable groups. It was first proved to hold for certain profinite groups by S. Koppelberg and J. Tits [@koptits] and has subsequently been verified for a large number of primarily subgroups of the infinite symmetric group. S. Shelah [@shelah], on the other hand, has constructed a group of cardinality $\aleph_1$ having width $240$ with respect to any generating set, so, in particular, the group is Cayley bounded, but


do homeomorphism groups of compact metric spaces have property (OB)? What about the isometry groups of bounded Polish metric spaces? (Some special cases will be verified in the following.)

Recall that a mapping $f$ between metric spaces $X,d$ and $Y,\delta$ is called a Hölder$(\alpha)$ map for some $\alpha>0$ if there is a constant $c\geq 1$ such that $$\delta(f(x),f(y))\leq c \cdot d(x,y)^\alpha$$ for all $x,y\in X$. Hölder$(1)$ mappings are thus simply Lipschitz mappings.

Let $G$ be a Bergman group acting by Hölder maps on a metric space $(X,d)$. Then the action of $G$ is semi-simple, i.e., $\{{\overline}{G\cdot x}\}_{x\in X}$ partitions $X$ into (bounded) invariant pieces each on which $G$ acts minimally. Moreover, there is an $N$ such that any $g\in G$ is Hölder$(\alpha)$ with constant $N$ for some $\alpha\in [1/N,N]$.

The sameabelian torsion group contains a basic subgroup.

An infinite abelian group has a countably infinite quotient group.

[*Proof :* ]{}

Let $G$ be an infinite abelian group and $T$ its torsion subgroup. Then $G/T$ is torsion free and hence embeds into a direct sum of copies of ${\mathbb Q}$, $G/T\sqsubseteq  \oplus_{i\in I}{\mathbb Q}$. If $G$ is not itself a torsion group, then the projection of $G/T$ onto one of these summands must be non-trivial and thus there is some non-trivial quotient of $G/T$, and hence of $G$, which is isomorphic to a subgroup of ${\mathbb Q}$. Clearly, this quotient is countably infinite.

So we can assume that $G=T$, i.e., that $G$ is a torsion group. Therefore, by the theorem of Kulikov, let $H$ be a basic subgroup of $G$. Assume first


is also an isometry of $Y$. Thus, every partial isometry of $X$ extends to a full isometry of $Y$.

We now need the following concept, which will also be used in a later section.

Suppose $G$ is a Polish group and consider for each finite $m\geq 1$ the diagonal conjugacy action of $G$ on $G^m$ given by $$g\cdot(h_1,\ldots,h_m)=(gh_1g{^{-1}},\ldots,gh_mg{^{-1}})$$ $G$ is said to have [*ample generics*]{} if for each $m\geq 1$ there is a comeagre orbit in $G^m$ for this action.

Notice that since $\Omega$ is countable, ${\rm Iso}(\Omega)$ is a Polish group in the permutation group topology. In section 5 (A) of Kechris and Rosendal [@kecros] it is shown how the above extension property for finite rational metric spaces of bounded diameter $1$ implies that ${\rm Iso}(\Omega)$ has ample generics andtherefore work in some subfield of ${\mathbb R}$ too. This would give similar results for the orthogonal group of the real separable Hilbert space, but we shall be content with the above setting. Notice first that ${{\boldsymbol}Q}$ is dense in ${\mathbb C}$.

We let ${\mathbb V}$ be the ${{\boldsymbol}Q}$-vector space with basis $(e_i)$ and notice that ${\mathbb V}$ is a dense subset of $\ell_2$. The inner product restricts to an inner product on ${\mathbb V}$ taking values in ${{\boldsymbol}Q}$, as ${{\boldsymbol}Q}$ is a field closed under complex conjugation. Since ${{\boldsymbol}Q}$ is algebraically closed, the norm of an element of ${\mathbb V}$ also belongs to ${{\boldsymbol}Q}$. This will give us enough space to perform the usual tasks of Gram-Schmidt orthonormalisation etc.

Our first result is the following extension property.

Let $T$ be


the conjugacy class of the $m$-tuple $(K_1,\ldots,K_m)$ is comeagre in ${\mathcal}U({\mathbb V})$.

By Lemma \[hrushovski\] we see that for any $P_1,\ldots, P_m\in
{\mathcal}U({\mathbb V})$ and $v_1, \ldots, v_k\in {\mathbb V}$ there are finitary operators $H_1, \ldots, H_m\in{\mathcal}U({\mathbb V})$ such that for all $t\leq
m, s\leq k$, $P_t(v_s)=H_t(v_s)$.

So list all $m$-tuples ${\mathsf K}=(K_1,\ldots,K_m)$ of unitary operators on some common finite-dimensional subspace ${\mathbb V}_i=[e_1,\ldots,
e_i]$ as $${\mathsf K}_1=(K^1_1,\ldots,K^1_m), {\mathsf K}_2=(K^2_1,\ldots,K^2_m),\ldots$$ and let $a_n$ be the dimension of the space $[e_1,\ldots, e_i]$ on which the $K_1^n, \ldots, K_m^n$ act. Let also $b_n=\sum_{j=1}^na_j$. We suppose furthermore that each ${\mathsf K}_i$ is repeated infinitely often.

We can now paste these operators together as $$M_t=
\left[\begin{array}{ccccc}
K_t^1 & &&\\
& K_t^2 &&\\
&& K_t^3&\\
&&&\ddots
\end{array}\right]$$ In other words, $M_1, \ldots, M_m$ are disjoint sums of unitary operators on finite-dimensional spaces of the form $[e_l,\ldots,e_k]$$A_t$. For if $(P_1,\ldots,P_m)$ is above, then the tuple can be approximated arbitrarily well by a tuple of finitary operators. So we can suppose that $P_1,\ldots,P_m$ are finitary themselves. Assume that we want to approximate $P_1,\ldots, P_m$ on ${\mathbb V}_k=[e_1,\ldots, e_k]$, where $k>b_i$ is such that $P_t(e_p)=e_p$ for all $t\leq m$ and $p\geq k$. Then we can find $j>i$ such that $k=b_i+a_j$ and $$P_t=\left[
\begin{array}{ccccc}
M_t{\!\upharpoonright}_{{\mathbb V}_{b_i}} & & \\
& K_t^j &\\
& & I
\end{array}\right]$$ Find a unitary operator $T$ such that $T{\!\upharpoonright}[e_1,\ldots,e_{b_i}]=
I_{b_i}$ and $T$ sends the ordered basis $\{e_{b_{j-1}+1},\ldots,e_{b_j}\}$ to $\{e_{b_i+1},\ldots,e_{b_i+a_j}\}$. Then $$TM_tT{^{-1}}= T\left[
\begin{array}{cccc}
K_t^1 & &\\
& K_t^2 &\\
&&\ddots
\end{array}\right]T{^{-1}}=
\left[
\begin{array}{ccccc}
M_t{\!\upharpoonright}_{{\mathbb V}_{b_i}} & & \\
& K_t^j &\\
& & B_t
\end{array}\right]$$ for some $B_t$. Thus $TM_tT{^{-1}}$ agrees with $P_t$ on ${\mathbb V}_k=[e_1,\ldots, e_{b_i+a_j}]$ for every $t=1,\ldots,m$.

A similar argument shows that the conjugacy class of $(K_1,\ldots,
K_m)$


of the rational Urysohn metric space, ${\rm Iso}({\mathbb U}_{\mathbb Q})$, with the permutation group topology, has ample generics and a cyclically dense conjugacy class. Moreover, in Kechris and Rosendal [@kecros] it is shown that Polish groups with ample generics and a cyclically dense conjugacy class cannot be written as the union of a countable chain of proper subgroups. So this means that ${\rm Iso}({\mathbb U}_{\mathbb Q})$ has property (FA). Moreover, V.G. Pestov [@pestov] shows that ${\rm Iso}({\mathbb U})$ has no non-trivial continuous representations by isometries in a reflexive Banach space, so in particular it has property (FH). However, this does not solve the corresponding problem for ${\rm Iso}({\mathbb U}_{\mathbb Q})$.

[99]{} Atkin, Christopher J. [*Boundedness in uniform spaces, topological groups, and homogeneous spaces.*]{} Acta Math. Hungar. 57 (1991), no. & 103619293824707388  & 0.866 \\
  13 & 7983517393715262672 & 9176358300744339432 & 0.870 \\
    \hline
\end{array}
Because of the exponential nature of this problem, calculating the success rate for larger $N$ would be pretty hard – at least with this approach.


Pederast Homosexuality at the time. But on the other hand such practices were not only VERY common in India, but were a way of living of Hindus. A greek sophist of the Roman imperial period, Philostratus has devoted two and a half of the eight books of his Life of Apollonius (1.19–3.58) to the description of a journey of his hero to India. So its clear that traveling to India for things like medical treatment, education (Pythagoras traveled to India for treatment of his Epilepsy, thats when he came across the advanced ideas of Geometry taught in Indian 'Gurukuls'. Whatever that has been attributed to him is actually Indian knowledge.)
Because of Apollonius' Yogic skills, Apuleius ranked him with Moses and Zoroaster. Lampridius tells us that Alexander Severus includedfor what you find. Don’t say you weren’t warned.

I just want to make a few points.

First, much of the most trenchant criticism of Paul and his cultish followers (more on them later) comes from people who are sympathetic with many of the position he takes. These critics think that government is far too large, and that our liberties have been progressively (pun intended) eroded. And I agree.

But the dislike of Paul and the Paulians for the government has curdled into a hatred of America. There is no ugly anti-American conspiracy theory that they do not embrace. 9-11 Trutherism, for instance. They routinely recycle theories first floated by the KGB. No wonder RT loves Paul and gives Rockwell plenty of air time. And it is this profound anti-Americanism that


libertarian label, that many like me are revisiting Hayek’s question: what’s my name again? And further: what is the practical political program that will lead to a smaller, less intrusive, less controlling, less destructive state? That is what Hayek pondered. That is what Friedman wrote about. That is what serious Smithian liberals think about today. That is not what Ron Paul and the Paulians do. And what they do gives libertarianism a bad name.

There isn’t much honor in the whole of the political class at this time and so the prospect of reducing the size of this class does hold attraction. Your point about easy solutions applies to the whole of election politics. Complete misrepresentation of reality has become the abominable norm.

I can’t imagine the common theme ofusing Carto mailing lists, which proved lucrative. What Paul did was a carry over. In short, the neo-confederates want Russia to take out Washington so they can have a fascist Southern republic. They already have their own constitution as well: google Tom Moore or Thomas Moore, constitution and Southern National Congress (all together). It’s frightening.

I guess the general left and others would feel tingly better about Israel if they instituted public stonings of women for adultery and a minimum 100 lashes for sorcery. Also all this business about putting former presidents in prison for sexual harassment charges absolutely must stop.

S/O-you completely missed the point of this post whether by choice or other (I will not further describe other).

Ron Paul is the only major US politician who still respects


that Obama would have more chances against Ron Paul than against a “mainstream” Republican candidate? I agree! I also happen to think that whatever his faults, Obama is still a far better bet than a grey apparatchik like Romney or insidious, ignorant demagogues Gingrich or Perry who are worshiped around these parts of cyberspace.

Ah Professor, I await your strongly worded criticism of the CME and Wall Street’s dear Fed for these endless ‘currency swaps’ with those bankrupt, decadent, Russia-appeasing EUrosocialists. Nary a peep of audit or even abolishing the institution that the U.S. functioned with successfully without until 1913 and that has created a 95% decline in the dollar’s value since then. Just a strongly worded ‘critique’ from an ornery cuss who knows the Establishment will turn onfacts was Paul’s opposition to the Patriot Act. The Professor’s observation is timely in that these simple labels are becoming less objectively applicable and without commonly understood meaning particularly with respect to current American conservatism and libertarianism.

My guess is you would be in British terms a classical liberal. Unfortunately, the word liberal has been mangled beyond all recognition in the US in the same way libertarian has, both having been turned into insults.

[…] Worldwide though we are seeing people rise up against central planning. It’s the millions versus the monolith. The Arab spring was something that could not have been fathomed 10 years ago. Some say its the result of social media, others the Iraq War, and some say a little of both. In China, people are becoming


good job of demolishing the Proudhonists, Blancians, etc. – of which you are one. For critiques of direct democracy, see Aristotle.

Re our name: Bastiatians?, Hayekians? Or how about the sons or children or lovers of liberty?

Re reading and writing posts – a new motto: Absinth makes the heart grow fonder. or at least more tolerant!

I definitely disagree with the article. First of all, the newsletters were not written by Paul and he did not have knowledge of them until after the fact. He’s repeatedly said this; however, those who do not like his views, like to bring this up often, ignoring the part where we all learned he didn’t write them. Even the writing style and the kind of language used is very different from his writings.

Secondly, 9/11done little research. I would ask the same of Republicans who attack Democrats, and Democrats who attack Republicans, and independents who attack them both.

“And it is this profound anti-Americanism that repels people like me, and other Paul critics–people who believe that America is flawed but the last, best hope of mankind that has on balance been a profound force for good at home and in the world at large.”

This is just nationalistic self glorification. The usa do what other countries, given the size, would have done if it could: trying to increase its control and influence around the world. And what “hope” are you talking about? If we were talking about usa anno 1776 or so, I would agree, but we don`t. Have you forgotten that the american


is as follows: Any answer that makes any effort to be helpful, deserves at least 1 upvote. Even if the answer is wrong (unless its blatantly wrong). If it's a few paragraphs and kinda goes above and beyond, it deserves 5 or 6 upvotes. If it really goes the extra mile to be completely thorough, and it seems the author did special research for the answer, that deserves more than 10. If an answer is really long and really thorough, but it doesn't answer the question in any way (I've seen this a lot), it deserves one upvote at the most. I hate it when people do that. Blatant rep mining. Unless they post an apology or something explaining how they mis-interpreted the question, I'll most likely voteother great biomolecular visualizations out there, particularly
around kinesin

[https://www.youtube.com/watch?v=y-uuk4Pr2i8](https://www.youtube.com/watch?v=y-uuk4Pr2i8)
[https://www.youtube.com/watch?v=7sRZy9PgPvg](https://www.youtube.com/watch?v=7sRZy9PgPvg)

~~~
rotskoff
This is actually a heavily criticized animation within the computational
biophysics community. Our intuition for physical determinism breaks down at
the nanoscale. One major fault of this video is that, at low Reynolds number,
there's essentially no inertia. So the representation of kinesin taking
deterministic, 100% processive steps is an absurd idealization. The motion is
dominated by thermal fluctuations (which, by the way, are occurring on a
nanosecond timescale).

At the same, even as a biophysicist, I think these animations are superb
learning tools. Those beautifully rendered animations actually describe the
mechanism in far greater detail than, say, textbook diagrams. One should just
be aware that fluctuations dominate at these scales.

------
icegreentea
I remember watching these animations in high school biology class. They've
definitely had this big long-term impact on how I visualize and


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For more information on the UAE please visit the official site on : www.uaeinteract.com
... Read more »2158, 2787, 3416, 4045?
629*p + 271
What is the c'th term of 134, 269, 404, 539, 674?
135*c - 1
What is the z'th term of -486, -604, -722?
-118*z - 368
What is the w'th term of -304, -830, -1576, -2542?
-110*w**2 - 196*w + 2
What is the u'th term of -1856, -1841, -1826?
15*u - 1871
What is the p'th term of -180, -241, -350, -513, -736, -1025, -1386, -1825?
-p**3 - 18*p**2 - 161
What is the y'th term of 761789, 1523576, 2285363, 3047150, 3808937, 4570724?
761787*y + 2
What is the w'th term of 682, 705, 750, 829, 954, 1137, 1390?
2*w**3 - w**2 + 12*w + 669
What is the n'th term of -1176, -2437, -3786, -5223, -6748?
-44*n**2 - 1129*n - 3
What is the u'th term of -194, -584, -1366, -2648, -4538?
-18*u**3 - 88*u**2 - 88
What is


bit of information. The LPOS values of two consecutive LPOS words differ by one. Accordingly, an LTO drive can position the data/servo head assembly down a tape to a given LPOS value with a longitudinal resolution of 7.2 mm by using the LPOS information. The timing-based servo format has not changed over five generations of LTO drives (LTO-1 to LTO-5).
Optimum detection of the servo patterns is achieved by a synchronous servo channel employing an interpolator/correlator, which ensures that optimum filtering of the servo reader signal for extraction of timing information is performed not only at constant tape velocity, but also during acceleration and deceleration. A synchronous servo channel thus ensures the optimum processing of a servo signal for the generation of head lateral position estimates, velocity estimates, andIt seemed to be the source of power for the entire
complex, and everything in proximity to the roiling, crystalline material
seemed to warp and twist. They called this element ‘Terrestrial Aether’, and
learned much of its practical application.

The complex was
greater than the fabled library of Alexandria,
and soon the Consulate had learned enough to put some of their new inventions
into practice. Giving new instructions to their factories across France,
the fires of industry burned day and night. With the application of Terrestrial
Aether, metal could be made both lighter and stronger, any number of devices
could be powered without coal or oil, medicines of previously unimagined
potency could be concocted, and mankind could at last take to the skies in
small airships, the likes of which had never before been seen. Most interesting
to young Louis-Napoleon, however,


will of the people, but that soon changed when Louis-Napoleon
unleashed his super-weapon upon the Palais
Bourbon, sundering it with a shot launched from over a mile away, and
reducing it to ash. His army then marched into Paris in a display of power, and as the
people cheered and shouted for a new Emperor Napoleon, Charles X relinquished
the throne.

Dismayed
that the Consulate of Peace had resorted to military might, Adolphe Thiers
nonetheless continued his plan. He swiftly set his supporters in place as a new
National Assembly, and began dismantling the old monarchy and last vestiges of
Catholic power. The cathedral of Notre Dame was rededicated as the home of the
Cult of Reason. Charles X was imprisoned for his crimes against the people, but
his son, Louis Antoine, Duke of Angoulême, was exiled to Britain, underthis in my car,” he said as he reached into his pocket. I held my breath. Out came an empty holy water bottle, which he simply wanted to fill. “My dog is dying, and I figured I’d try blessing him as a last resort.” He smiled, suddenly looking innocent as a lamb.

I reached into the drawer next to me to retrieve the holy water bottle and watched shame-faced as he filled his little container with the blessed sacramental.

“Take the wooden beam out of my eye, Lord,” I prayed after the poor man left, embarrassed over my judgment of both him and the political candidate.

I had definitely gotten the point. And I could almost hear God giggling in the silence.

Judy Landrieu Klein is an author, theologian, inspirational speaker, widow


rest of us are hapless pie-in-the-sky types who don’t get things done?

Clearly, Clinton’s self-characterization was meant, at least in part, as a diss aimed at Bernie Sanders. During primary season, Sanders and Clinton debated the question of who and what qualifies as progressive. When reporters asked Bernie whether Hillary is a “true progressive,” he replied, “I think, frankly, it is hard to be a real progressive and to take on the establishment in a way that I think has to be taken on, when you come as dependent as she has through her super PAC and in other ways on Wall Street and drug-company money.”

At a Democratic debate a few days later, Clinton was asked to respond. “I am a progressive who gets things done. And the rootand ADV to develop its care-matching technology and grow its team.

Cultivate’s chief commercial officer, Andy Robinson, said: “The Care Sourcer team is tackling one of society’s greatest challenges. The technology has the potential to scale and transform the care sector and we’re excited to be supporting this journey. It’s also great to see two Edinburgh tech companies working so closely together, and we’re proud that our team’s expertise can play a part in tackling such a significant challenge.”

Charles Harley said: “We are on track to build industry-leading technology to tackle the UK’s care crisis, and it’s great to do that with the support of a high quality team like Cultivate. It’s further evidence of Edinburgh growing its credentials as a world-class engineering hub.”

Andrew McGinley said: “We’ve known the


in Hobart
Category:Casino hotels
Category:Sandy Bay, Hobart
Category:1973 establishments in Australiamouse generation are provided in the [Supplementary Material](#SM1){ref-type="supplementary-material"}. Details of the CIA experimental procedure, with the arthritis score for each mouse, are given in [Supplementary Material](#SM1){ref-type="supplementary-material"}. Animal experiments were performed after approval by the ethical committee of the University of Perugia.

*A. tonkinensis* Extracts
-------------------------

Leaves of *A. tonkinensis* were harvested in Hanoi, Vietnam in October 2015, and the voucher species (No. AT-2015) was deposited in the Institute of Chemistry, Vietnam Academy of Science and Technology. Briefly, freshly harvested leaves were air-dried for 2 days and oven-dried at 40--50°C in a forced-air oven. To obtain the decoction, 5 g dried *A. tonkinensis* leaves were boiled 3 times in a total volume of 100 mL (5 g/100 mL final concentration) distilled water. The decoction was then given to mice *ad libitum* instead


cells.

![Effect of decoction and TAT-2 on isolated mouse splenic CD4^+^ T lymphocytes. **(A)** Number of untreated mouse splenic CD4^+^ T lymphocytes (Control), Th17-polarized (Th17) cells, and Th17 polarized treated with At (Th17 At). **(B)** Expression of *IL-17* (left) or *RORC* (right) in these groups was measured by real-time PCR. Bars represent values ± 1 SEM from three independent experiments. Statistical analysis was performed with a Student's *t*-test: ^∗∗∗^*p* ≤ 0.001, ^∗∗^*p* ≤ 0.01. **(C)** Transcription of *IL-17* (left) or *RORC* (right) by real-time PCR in CD4^+^ splenic lymphocytes stimulated with anti-CD3 plus anti-CD28 monoclonal antibodies (Control), polarized to Th17 differentiation (Th17), or polarized and treated with varying concentrations of TAT-2. Bars represent absolute expression levels ± 1 SEM of three independent experiments.](fphar-10-00503-g006){#F6}

Since TAT-2 ([@B22]) is one of thecan be found online at: <https://www.frontiersin.org/articles/10.3389/fphar.2019.00503/full#supplementary-material>

######

Click here for additional data file.

At

:   *Artocarpus tonkinensis* decoction

IL

:   interleukin; CIA, collagen-induced arthritis

mAbs

:   monoclonal antibodies

RA

:   rheumatoid arthritis

RANKL

:   receptor activator of nuclear factor kappa-B ligand

VTM

:   Vietnamese traditional medicine.

[^1]: Edited by: Judit Hohmann, University of Szeged, Hungary

[^2]: Reviewed by: Wei Wei, Anhui Medical University, China; Ricardo Machado Xavier, Federal University of Rio Grande do Sul, Brazil

[^3]: This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology


You’d go out and just go straight from the club to the stadium on Sunday.”

That changed, Houshmandzadeh said, when Marvin Lewis became the head coach. But Mike Brown continues to own the team. And he continues to understand the connection between minimizing expenses and maximizing profits.

Houshmandzadeh has said publicly that he and others who know how the Bengals do business won’t be saying bad things about the Bengals to Burrow. But with Houshmandzadeh already saying negative things publicly, he doesn’t need to say anything privately to Burrow.

Actually, nothing Houshmandzadeh says should matter much. Former Bengals franchise quarterback Carson Palmer, a No. 1 overall pick, already has said it all. He believes based on his time with the team (and with other teams) that the Bengals aren’t trying to1 + 5, -m*i - 3*n - 4 = 0 for i.
-2
Suppose -18 = i + 5*a, 4*i - a = 8 + 4. Let t be i - 5/(5/(-3)). Suppose t*z = 12 + 13. Solve -z*y - 15 = 2*h, 3*y = 3*h - 4*h - 10 for y.
-5
Let g(u) = -17*u**2 + 2*u + 17. Let p(l) = 6*l**2 - l - 6. Let r(q) = -4*g(q) - 11*p(q). Let s be r(2). Solve s = -b - 4*c, 2*c + 6 = -4*b - 14 for b.
-4
Suppose 2*j = 5*k - 19, -j - 4*j + 35 = 4*k. Solve -4*m - 3*z = -16, -16 = -4*m - 0*m + j*z for m.
4
Suppose -5*b + b + 2*j = 28, -3*b = -4*j


-5*v = h - 0*v + 10, -s = 3*h - v for h.
-5
Suppose 4*u - 36 = u. Let v be (-8)/(-10)*30/u. Solve 0 = 3*k - 4*h + 11, 3*k - h = -v - 12 for k.
-5
Suppose 2*l + 0 = -12. Let j be (-30)/(-8) + l/(-24). Suppose 2*w = 5*p - 8, 16 + j = -p - 5*w. Solve -2*u - 5*q = 16, 0 = -p*q + 4*q + 8 for u.
-3
Suppose -3*f + 2 = -4. Solve 4*c + 3*q = -f*q - 8, -2*c = -5*q + 4 for c.
-2
Let r be (-6)/(-57) + 1014/114 + -6. Suppose -5*t = 20, 4*t = 7*s - 2*s - 41. Solve -3*c + 4 = 4*q + 3, -s*c + r*q577, 92 S.Ct. at 2709. Where restrictions exist as to how an employee may be terminated, the employee has a constitutionally protected property interest. O'Donnell v. Village of Downers Grove, 656 F.Supp. 562, 566-67 (N.D.Ill.1987); see Gates v. Sicaras, 706 F.Supp. 169, 172 (D.Conn.1989). Plaintiff claims that she had a written contract which provided that she could be terminated only for cause. Defendants claim that she was an employee-at-will.
It is unnecessary, for purposes of this motion, to determine whether plaintiff, as a legal matter, was an at-will employee, as defendants are entitled to qualified immunity. "[G]overnment officials performing discretionary functions, generally are shielded from liability for civil damages insofar as their conduct does not violate clearly established statutory or constitutional rights of which a reasonable person would have


pic.twitter.com/pa8qiI1thv — ALX 🇺🇸 (@alx) September 23, 2019

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*Correction: Our previous information referred to Thunberg as Swiss but she is Swedish.membrane. This method has two main advantages over the previously implemented methodologies; first, it is completely deterministic since no stochastic move like particle insertion–deletion is needed, and second, it allows us to perform simulations of mixture permeation through membranes at fixed feed composition.

We first explain the new methodology and then demonstrate it by simulating permeation of pure methane (CH4), ethylene (C2H4) and ethane (C2H6) through a zeolitic imidazolate framework-8 (ZIF-8)28 membrane, and by applying it for the separation of an equimolar ethylene/ethane mixture, again in a ZIF-8 membrane. We chose the separation of ethylene from ethane due its paramount importance. Market data confirm the necessity of this separation; the demand of ethylene as feedstock in chemical industry for production of rubbers, plastics and other valuable chemical products is


in the control regions and needs to be tuned (see Table S1 and Fig. S1†). We underline that, in order to establish a steady state concentration gradient, the use of periodic boundary conditions (PBCs) along the z direction is crucial. Indeed, as the molecules permeate through the membrane, they can flow from the outlet of the membrane back to the inlet region, establishing a stationary flux. A detailed discussion of eqn (1) & (2), as well as the definition of G, can be found in the work of Perego et al.27

Fig. 1 Conceptual representation of the concentration gradient driven MD method. Red line demonstrates an arbitrary concentration profile. Dashed line shows the boundaries of the simulation box. Fluid molecules return to feed side from the permeate side through5 blocks.

A private version of PLUMED 2.2.2 plugin35 was used to apply the bias forces, FIi and FOi, in order to control concentrations in ICR and OCR. Target concentration in the ICR was set to a molecular density which corresponds to the total feed pressure (which varied between 2 to 40 bars in our simulations) based on the pressure/density data from the NIST database.36 The target concentration in the OCR was set to 0 to create a vacuum effect on the permeate side in all simulations. Here we note that in MD simulations of membranes creating a vacuum effect is a challenging task as also mentioned by others.15,21 To create the vacuum effect, a larger outlet force constant, kOi, was used compared to the inlet force constant, kIi.


in ICR were set to the molecular density of the fluid at 40 bar (feed pressure). In all cases concentration of the species are stable and fluctuate around an average value. The average concentrations calculated for ICR and OCR are given in Table 1 for each fluid. For the inlet the standard deviations are very small in comparison to the average concentrations, which demonstrate excellent control of the concentration in ICR. The relatively high fluctuations in OCR with respect to the average values indicates the difficulty of controlling the concentration at very low target values (see Fig. S3† for OCR concentration data plotted on a smaller scale). However, such fluctuations are actually insignificant because the number of molecules present in the OCR at any time is extremely smallcreate some value (action).
The interesting question here is, if you define a function, what exactly is sent to the RDD (and distributed among different nodes, with its transfer cost)? A nice explanation  here:
http://spark.apache.org/docs/latest/programming-guide.html#passing-functions-to-spark


level of IFIT1 and IFI27 expression was observed in U251EGFR cells compared to vector transfected cells confirming that IFIT1 and IFI27 expression is driven by EGFR ([Figure 1c and d](#F1){ref-type="fig"}). Surprisingly, addition of EGF to cells abrogated EGFR induced expression of IFIT1 and IFI27 ([Figure 1c and d](#F1){ref-type="fig"}) arguing against an autocrine mechanism for expression of these genes. In addition, inhibition of EGFR kinase activity with Erlotinib results in a block of IFIT1 and IFI27 induction indicating that these genes are induced by EGFR activity ([Figure 1c and d](#F1){ref-type="fig"}). Importantly, although increasing EGFR expression in multiple cell lines results in tyrosine phosphorylation of the EGFR, it does not result in ERK or Akt activation unless EGF is added ([Figure 1e](#F1){ref-type="fig"}, and [Supplementary Fig. 1a--b](#SD1){ref-type="supplementary-material"}), suggesting that constitutive andexpression of IFIT1 and IFI27 in U251EGFR cells. Silencing of IRF3 blocked constitutive EGFR induced expression of these genes compared to control (scrambled) siRNA transfected cells ([Figure 3a--b](#F3){ref-type="fig"}). A similar result was found in U87EGFR cells ([Supplementary Fig. 6a--c](#SD1){ref-type="supplementary-material"}). Furthermore, re-expression of IRF3 following IRF3 knockdown restored EGFR induced expression of IFIT1 and IFI27, arguing against a non-specific siRNA effect and supporting a specific role for IRF3 ([Figure 3d--f](#F3){ref-type="fig"}). These experiments suggest that IRF3 is required for EGFR mediated upregulation of IFIT1 and IFI27.

Constitutive EGFR signaling results in IRF3 activation {#S5}
------------------------------------------------------

IRF3 is a key transcription factor involved in antiviral responses and is activated by stimuli such as double stranded RNA and TLR signaling^[@R29]^. IRF3 is known to bind to the interferon sensitive response element (ISRE). To investigate whether


constitutive or ligand-induced EGFR signaling induces phosphorylation of IRF3 and/or TBK1. Indeed, we find constitutive serine phosphorylation of IRF3 in U251EGFR cells that is abolished by Erlotinib and by EGF, indicating that it is EGFR driven and also a feature of constitutive EGFR signaling ([Figure 6a](#F6){ref-type="fig"}). [Figure 6A](#F6){ref-type="fig"} also shows a low level of EGFR tyrosine phosphorylation in the absence of ligand. In addition to IRF3, TBK1 is also phosphorylated in U251EGFR cells. Addition of EGF or Erlotinib abolishes TBK1 serine 172 phosphorylation in U251EGFR cells ([Figure 6b](#F6){ref-type="fig"}). Similarly, IRF3 and TBK1 are phosphorylated in MDAMD468 cells and exposure to EGF or Erlotinib abolishes this phosphorylation ([Figure 6c--d](#F6){ref-type="fig"}). Also, silencing EGFR in MDAMB468 cells results in a loss of IRF3 activation ([Figure 6e](#F6){ref-type="fig"}). We did not detect tyrosinein GBM. In high EGFR expressing tumors, we would predict that in tumors with low levels of ligand, constitutive EGFR signaling would be prevalent leading to increased expression of IRF3 mediated gene expression. Indeed, we find that there is an inverse correlation between TGFα levels and IFIT1 and IFI27 levels in GBMs that express a high level of EGFR. Thus, the presence or absence of ligand in individual tumors may determine signaling networks activated by the EGFR, and, in turn, may have important implications for targeted treatment.

Methods {#S14}
=======

Plasmids transfection and generation of Cell lines {#S15}
--------------------------------------------------

U251MG cells were obtained from Dr. Robert Bachoo. U87MG and MDA-MB-468 cells were obtained from ATCC. 429NS cells were provided by Dr. Santosh Kesari. The glioblastoma cell lines U251MG was used to generate cell


(vector transfected cells). Addition of EGF leads to a statistically significant decrease in reporter activity. Furthermore, Erlotinib also downregulates reporter activity, indicating that the high IRF3 transcriptional activity in the absence of EGF is driven by EGFR. **(b)** The same experiment as A was conducted in U251EGFR cell using an IFI27-Luc reporter. **(c)** The EGFR induced transcriptional activity of IRF3 is not blocked by Cetuximab compared to control IgG in U251EGFR cells. **(d)** A kinase inactive EGFR (EGFRK-) fails to activate the pISRE-Luc reporter in U251 cells, whereas the EGFRwt efficiently activates the reporter. Data for **(a--d)** were analyzed by 1 way ANOVA followed by Tukey's multiple comparison test. **(e)** A CHIP assay examining IFIT1 promoter occupancy by IRF3 in U251EGFR cells with or without EGF. IRF3 promoter$$\hat{M}^2_Z\approx m_z^2\left (1-\sum_{n=1}\frac{m_z^2F_n^2}{m_n^2}+\mathcal{O}(m_n^{-4})\right )$$ If we now define the predicted weak mixing angles to be $$\label{spcp}
s_p^2=\frac{1}{2}\left (1-\sqrt{1-\frac{4\pi\alpha}{\sqrt{2}G_f\hat{M}_Z^2}}\right ),\qquad c_p^2=\frac{1}{2}\left (1+\sqrt{1-\frac{4\pi\alpha}{\sqrt{2}G_f\hat{M}_Z^2}}\right ).$$ Then after a little algebra one arrives at the result $$\label{ }
s_Z^2\approx s_p^2\left (1-\frac{c_p^2}{c_p^2-s_p^2}\sum_{n=1}\left [\frac{m_z^2F_n^2}{m_n^2}-\frac{m_w^2\left(F_n-F_\psi^{(n)}\right )^2}{m_n^2}\right ]+\mathcal{O}(m_n^{-4})\right ).$$ Likewise the correction to the W mass can be computed using an analogous method $$\label{ }
M_W^2\approx c_p^2\hat{M}_Z^2\left (1+\sum_{n=1}\left [\frac{(m_z^2-m_w^2)F_n^2}{m_n^2}\right ]+\frac{s_p^2}{c_p^2-s_p^2}\sum_{n=1}\left [\frac{m_z^2F_n^2}{m_n^2}-\frac{m_w^2\left(F_n-F_\psi^{(n)}\right )^2}{m_n^2}\right ]+\mathcal{O}(m_n^{-4})\right ).$$ Note that provided $F_\psi^{(n)}<F_n$, the W mass is always shifted in the correct direction with regard to recent precision measurements at the Tevatron [@Aaltonen:2007ps]. Another quantity of importance for EW observables is the extent to which the Z coupling is perturbed by the boundary mass, which using (\[Uinv\]) is given by $$\label{ }
\sqrt{g^2+g^{\prime\;2}}f_Z^{(0)}\approx \sqrt{g^2+g^{\prime\;2}} f_\psi^{(0)}\left (1-\sum_{n=1}\frac{m_z^2F_nF_\psi^{(n)}}{m_n^2}+\mathcal{O}(m_n^{-4})\right ).$$ This shows that the size of the EW


corrections is determined by three quantities, the relative gauge-Higgs coupling $F_n$, the relative gauge-fermion coupling $F_\psi^{(n)}$ and the of course the KK mass scale. In our best case scenario where the $F_\psi^{(n)}$ can be suppressed by, for example localising towards the UV brane, then the lower bound on the KK scale arising from EW corrections is largely determined by the scale of $F_n$. For example the 5D RS model with $F_n\approx8.3$ (for $\Omega=10^{15}$) typically has much larger constraints than that of universal flat extra dimensions with $F_n\approx \sqrt{2}$. A well known cure for these large constraints is to impose a custodial $SU(2)_R\times SU(2)_L$ symmetry on the bulk which essentially fixes $\rho\equiv\frac{m_w^2}{c^2m_z^2}$ to be 1 [@Agashe:2003zs]. The result of this is that when the additional $SU(2)_R$ gauge field is2001, when a U.K. citizen named Richard Reid did just that. In December of that year – just a few months after the attacks of Sept. 11, 2001, Reid tried to kill 197 passengers and crew members aboard an American Airlines flight from Paris to Miami by detonating explosives in his shoes.

Reid pleaded guilty the following year. He said he was a follower of Osama bin Laden and did not recognize the American justice system, but admitted to the acts outlined in an indictment against him. He was sentenced to life in prison.

In the more than 12 years since, Transportation Security Administration agents have asked travelers to doff their shoes at airport security checkpoints as a matter of standard operating procedure.

Under current TSA regulations, passengers 12 and under


of lupus nephritis were obtained from the medical records. The peripheral blood samples were obtained and allowed to clot prior to centrifugation. The sera were aliquot and stored at −80°C until respective analysis was carried out. Serum ICAM-1 and VCAM-1 levels were measured by using precoated ELISA kit (Cusabio, China) that employed the sandwich enzyme immunoassay technique for quantitative measurement of human ICAM-1 and VCAM-1 concentrations. The anti-C1q antibody levels were measured using precoated ELISA kit (Orgentec, Germany) that quantitatively measures the IgG subclass of antibodies against C1q in human serum or plasma. Analyses were carried out according to manufacturers\' protocols. Anti-dsDNA was measured semiquantitatively using Fluoro nDNA test (MBL, Japan) that employed*Crithidia luciliae* indirect immunofluorescent test (CLIFT) method. Anti-dsDNA with titer 1 : 10 was considered positive and thehigher (10.0%).

Anti-C1q antibody showed good correlation with anti-dsDNA and it was better correlated than VCAM-1. Anti-C1q antibody also showed significant moderate correlation with serum C3 and serum C4 levels. Interestingly, better correlation was seen between anti-C1q antibody and serum C3 compared to serum C4, as demonstrated by VCAM-1. This discrepancy between findings of sera C3 and C4 cannot be clearly explained. Other studies had also yielded conflicting results regarding relation of SLE disease activity with levels of sera C3 and C4. Some studies have found that serum C3 was superior in SLE disease monitoring, while some demonstrated the same for serum C4 \[[@B25]--[@B26]\].

Many of previous studies have found that anti-C1q antibody was a useful marker for lupus nephritis \[[@B10]--[@B31]\]. However, there were also studies that proved anti-C1q antibody


been driving the real estate business, and any downfall in the process can bring down the estates or rather elevate the cost of the property. Every process is similar to the process of the food chain that we studied in the school. It is an advanced version of the vicious cycle of life, where one sector is linked to another, and another goes on linked to some other sector. There is a loss in one sector and the other sectors also have to bear the consequences. It is a chain reaction where inflation of one country affects the other. The global scenario of the real estate business has affected the business in Indian land to a great extent. There is a demand for sustained growth, urbanization, expansion ofQ:

How can we extract values from a raster and put it in a shapefile?

I just started using QGIS for a research project and I am not at all familiar with the software nor the formats used. I have a shapefile representing the different departments of France, delimited by borders, and a TIFF file with data points from all over the world that I want to extract and put in the shapefile.
I would like to capture the data from the TIFF file and compute an average for each department (from the shapefile), and put the results in a table (one average data point for each department).
How to do that?

A:

Welcome to gis.stackexchange!
You are looking for the Zonal statistics raster analysis tool:

Under Raster layer select your raster, while Vector layer


development is an injustice. Economic growth is a necessary but not a sufficient condition of development and thus ought to be promoted in a frame work of equality, equity, environmental sustainability and respect of human rights for all irrespective of gender, sex, colour, opinion and social status. According to the National Development Plan, „‟the Ugandan Economy experienced varying growth rates when the Poverty Action Plan was being implemented, with an average GDP growth rate of 7.2% between 1997/1998 and 2000/2001 to 6.8% between 2000/2001 and 2003/2004, increasing to 8% over the period 2004/2005 to 2007/2008 (NDP I, 2010: i)‟‟. However, the plan is silent on how increased growth has enhanced the wellbeing, capabilities and livelihoods of the poor men and women in Uganda. We ought to be awaremanagement and structural reform between the 1990 and 2000s. The country was among the first Sub-Saharan African countries to embark on liberalization and pro-market policies in the late 1980s. During that time, a stable macroeconomic environment and sustained private sector-oriented reforms led to Uganda‟s graduation into a mature reformer in 2006. Real gross domestic product (GDP) growth averaged 7% per year in the 1990s and the 2000s (World Bank, 2008a)‟‟. Uganda is regarded as the African country that has adopted the neo-liberal reform package most extensively (Harrison, 2006). It is considered the star performer of liberal economic reforms and the poster example that other African (and other developing) countries on the verge of starting reforms should copy it in almost every aspect (Kuteesa, 2010). The country‟s „‟apparent success


2017(NDP1, 2010:43). Although the NDP claims to have been greatly informed by the experiences from PEAP which comprised of a number of human development imperatives, it categorically aims at eradicating poverty through promoting economic growth (NDP1, 2010). This economic growth yard stick was not derived from the views of the poor but is rather a view of neo-liberal technocrats in the ministry of finance. According to Amnesty International 2009 Human rights report: For the past two decades, the state has been retreating or reneging on its human rights obligations in favour of the market in the belief that economic growth would lift all boats. With the tide receding and boats springing leaks, governments are radically changing their positions and 38 J. Afr. Stud. Dev. talking about a newtrack and most seriously so on primary education completion and child and maternal mortality. This leaves Uganda with serious challenges to poverty reduction which, as is economic growth, is further hampered by the high population growth of 3.3% (Austrian Development Cooperation, 2010). Development in the region of Northern Uganda was affected by two decades of violent conflict. Towards the end of conflict, the poverty rate was estimated at 61% which is double the national average. Socioeconomic activities had virtually come to a standstill for most of the population in the central North and humanitarian assistance has become regular for several years. Confined within conflict, the population of the North in addition suffered from sociopolitical marginalistion in the national context. Violence, particularly against women and children, and land disputes


means of livelihood and are struggling to make ends meet. David Kureeba from the National Association of Professional Environmentalists (NAPE) / Friends of the Earth Uganda opines that: People‟s rights to land are being demolished despite protection for them under the Ugandan Constitution. Small scale farming and forestry that protected unique wildlife, heritage and food of Uganda is being converted to palm oil wastelands that only profit agribusinesses. The Ugandan Government must prioritise small scale ecological farming and protect people‟s land rights (Friends of the Earth International, 2012). John Muyiisha, a farmer from Kalangala, tells of how he woke up one morning to find bulldozers destroying his crops. He had on the land for 34 years. Other community members were contracted to plant palm oil and then forcedbe centered on social justice and human rights. CONFLICT OF INTERESTS The authors have not declared any conflict of interests. Kizito et al. 43 REFERENCES African Development Bank (2011). Eastern Africa Regional Integration Strategy Paper 2011-2015. Austrian Development Cooperation (2010) .Uganda Country Strategy 2010-2015. <http://www.entwicklung.at/uploads/media/Uganda_CS_20102015_01.pdf>, accessed on 15-8-2016. Chomsky N (2010). American Foreign Policy. <http://www.chomsky.info/talks/19850319.htm>, accessed 9-7-2016. Cox WR (2005). Civil Society at the Turn of the Millennium, Prospects for an Alternative World Order. In: Amoorel L(2005). The Global Resistance Reader London and New York: Routledge. Craig D, Porter D (2006). Development Beyond Neo-liberalism? Governance, Poverty Reduction and Political Economy. New York: Routledge. FIAN (2010).Mubende: Evictees Struggle to Get Access to Justice and Land. <http://fian.org/cases/cases2/mubende-uganda-coffeeplantation-by-neumann> accessed in 17-8-2016. Friends of the Earth International (2012). Land Grabbing for Palm


the ruling Congress and the main Opposition, BJP, the retired bureaucrat-turned-politician said: "If political parties are serious about curbing crime and making our city safe, they must put an end to the criminalization of politics."

"We can't have criminals make laws. They simply cannot be the custodians of law," added the 45-year-old.

Kejriwal went on to say that his party, if elected, would not only rigorously work towards fixing the deteriorating crime situation in Delhi, but also introduce stronger, more stringent laws.

"One of the first goals for us would be to bring in a strong anti-rape law. These tainted lawmakers are in no position to do that. Many of them, in fact, would themselves be behind bars if such a law were introduced."

Kejriwal was reacting to the findings of aQ:

AWS Webapp tutorial: how to choose source in database security group?

I am following the AWS tutorial to create a Webapp here: http://docs.aws.amazon.com/gettingstarted/latest/wah-linux/getting-started-create-rds.html
I am stuck at the part 'Create a Security Group for Your DB Instance'.
The tutorial instructs you to start writing 'WebserverSG' into the IP source, and to select an option. However, even after completely typing 'WebserverSG', no such option is presented and I am unable to create the security group.
Is there a way to know the source without selecting it from the options? Alternatively, have I done something wrong for the option to not be presented?
This is my first time dealing with AWS; I don't have a concrete understanding of the purpose of security groups - so please bear this in mind!
Thanks in advance for any answers.

A:

A


of dying businesses and obsolete capital. I think part of the problem here is arbitrary moral rules that don't actually help anyone.

What's the case for your claim that libertarianism leads to "monopolism"? The ideology deliberately weaken government which is the both the most powerful sort of monopoly out there and the principal creator of monopolies historically.

And what's supposed to be wrong with vulture capitalism? Capitalism has always been fairly good at disposing of dying businesses and obsolete capital. I think part of the problem here is arbitrary moral rules that don't actually help anyone.

There is an old business adage: "Nothing Succeeds like Success". It breeds corollaries such as "Nobody got fired for buying IBM". (Microsoft, for the younger generation).

A successful business breeds a positive feedback process just aspeople are among the most despised, least trusted people on the planet. I don't think there are any auto manufacturers that wouldn't kick independent dealerships to the curb if they could.

Tesla could probably sell their cars just fine if they contracted with the local dealerships. Why they don't... I do not know.

$$$$$$$

Dealerships don't work for free. They would either need to add at least $3k to the price of a bottom-end Model S or Tesla would have to eat that cost.

Also, I wouldn't rule out the dealers saying no to electrics on the basis of the lack of maintenance revenue. The stealerships wouldn't be able to charge Tesla drivers obscene rates for oil changes and such.

The stealerships wouldn't be able to charge Tesla drivers obscene rates for oil


read the laws tesla is lobbying for on their website, it's a rather specific exemption from the dealership law for basically them:

"a manufacturer of only all electric-powered or all battery-powered motor vehicles, or a distributor of only all electric-powered or all battery-powered motor vehicles, that (i) owned and operated a new motor vehicle dealership in the United States on or before March 1, 2013, and (ii) has never sold its line make in the United States through an independent franchised new motor vehicle dealership, may own or operate a dealer or dealership, or act in the capacity of a dealer, at any location within the state and may obtain a dealer general distinguishing number under Section 503.029 of the Transportation Code."

"let's write ourselves an exemption, but slam theof al-Qaeda that was seized in Sarajevo in 2002 during a raid of the premised of the Benevolence International Foundation. The operation, led by Bosnian police, uncovered what has been later labeled as “The Golden Chain,” a list later vouched by al-Qaeda defector Jamal al-Fadl that included 20 top Saudi and Gulf States financial sponsors.

Al-Aqsa Islamic Bank was 20% owned by Beit el-Mal Holdings, an investment group based in the West Bank with chapters in East Jerusalem and Gaza. The two financial institutions shared senior officers and directors, and a majority of their shareholders were renown to be affiliated with Hamas. Mohammed Sarsour, a U.S. citizen who served as Vice-President of Bir Zeit University, was both Deputy General of Al-Aqsa Islamic Bank and General Manager of Beit al-Mal


Holdings.

Beit al-Mal itself was originally established to fundraise and transfer money for associations that the Palestinian Authority had identified as associated with Hamas. Both Al-Aqsa Islamic Bank and Beit al-Mal Holdings are part owners of Sinokrot Global group and “cooperatively act[ed] as a buffer between Hamas and its donors.”

Cooperation with Citigroup
Shortly before the bank started operations, the affiliations with Hamas of several of its employers and board members became evident, and a number of banks refused to clear its transactions.

In particular, Al-Aqsa Islamic Bank's money laundering operation on behalf of Hamas cost the bank the possibility to do business in Israel. Therefore, in order to evade Israeli sanctions, Al-Aqsa Bank embarked on joint projects with Citigroup, intertwining itself the bank's Israeli division.

The joint projects with Citigroup ledfor single payer, Democrats should home in on this. Will you have to switch plans? Yes. But you will have to switch plans at some point anyhow, and when you do, you will be at the mercy of a system that will try to milk your changing circumstances, for profit, at your expense. Let’s deny them that power. Let’s switch, together, all at once, and then never again.

It will of course be an administrative challenge to transition the population to Medicare by a certain date. But the worst thing Democrats could do is try to outsource that challenge to millions of us who have better things to do in life than argue with insurance companies and collections agencies, and who don’t have $17,000 lying around to make the


malignant lymphoma. Of those patients not included in follow-up analysis, 14 had died from other causes, 47 had received a diagnosis of lymphoma within the past 5 years, and 21 were lost to follow-up. Among the 114 patients with a 5-year follow-up, 49 had died of the disease and 65 were alive (24 with lymphoma and 41 without). Analyses showed no difference in the distributions among survival categories relative to MCPyV status ([Table 5](#T5){ref-type="table"}). Of the MCPyV-positive patients for whom follow-up data were available, 3 (42.9%) of 7 were alive and in remission compared with 38 (35.5%) of 107 MCPyV-negative patients. There were 3 (42.9%) deaths among the MCPyV-positive group and 46 (43.0%) deaths among the MCPyV-negative group (p = 0.88).

###### Clinical outcomes for lymphoma patients over aSea Change German Shipyards See Future in Wind Power

After years of decline, Germany's shipyards are now pinning their hopes on offshore wind farms, a key component of the country's energy revolution. Some have converted entirely to building equipment for wind farms. But the initial euphoria has worn off as the true challenges of the transition become clear.


This causes guys from around the globe to look for drugs for erection dysfunction, remedies and the best medications. Just what exactly can you need to impress a girl sexually? It's very easy, a rock hard penis along with the capacity to come more than once. That is what all girls want! Along with Cialis Cheap Generic Cialis, Levitra and Viagra are such love medications which takes one to the degree of ideal hard-on during sexual intercourse. The best thing about these medications is the fact that all of them are are FDA approved for the treatment of ed. Isn't it enough to prove effectiveness and their dependability? Its reality these medications are not ineffective on over 90 90 individuals and numerous men are using everything over theRobinson gave as an example the fact that India moved, over the period it was a colony, from an informal, to a formal part of the empire, and then back to an informal part in its later years. An "informal empire," then, is not wholly distinct from a "formal empire," but indicates that the level of influence exerted by the mother country over this part of the empire is limited. Informal empire means that the mother country has successfully exerted political and commercial power over the country's territories, economy, people and resources, and is able to influence the political machinations of the subordinate country in pursuit of its own interests. However, there may not be any formal connection between the two countries, with the "conquered" country not bound


find the most innovative ways to make the lives of Canadians better."

Francesco Sorbara, Member of Parliament for Vaughan-Woodbridge

"The FedDev Ontario grant is the largest ever in Mohawk's 50-year history. The Government of Canada's investment in applied research at Mohawk will put our students and faculty to work with industry partners to test clean energy solutions that could revolutionize how we power our homes and communities."

Ron McKerlie, President, Mohawk College

Quick Facts

FedDev Ontario's non-repayable contribution, under the Investing in Commercialization Partnerships (ICP) initiative, will support total project costs of up to $9.3 million and will leverage investments from up to 11 strategic partners.

These partnerships will result in the development and commercialization of 11 technologies, such as energy-management software and energy storage.

FedDev Ontario Invests in New Site to Create Energy-Efficient Technologies

Thealso home to iDeaWorks, an internationally-recognized applied research and innovation centre, which focuses on leveraging multidisciplinary industrial collaborations to commercialize innovations in three high growth sectors: energy; e-health; and, additive manufacturing.

The Investing in Commercialization Partnerships (ICP) initiative supports business-led partnerships that create globally-competitive products, technologies and services, and the development of innovation platforms that can demonstrate commercial value.

For more information, visit the Investing in Commercialization Partnerships website.


cellular telephone or personal digital assistant (PDA). The portable communication device is traditionally carried in a case that is separate from the holster and that is also secured to an article of the user's clothing by a connecting clip.
As such, it is necessary for a law enforcement officer, combat personnel or individual possessing a CCW permit to carry both a handheld firearm holster and a cellular telephone case secured to their waistband. Carrying multiple devices is cumbersome. Additionally, due to the connecting clips it is not physically possible to position both the handheld firearm holster and the cellular telephone case in a location on the user that would be considered optimum for the handheld devices.
Accordingly, what is needed in the art is an apparatus capable of containing multiplepretty high. Good luck!

I'm not up enough on the new admission policy (the one that's supposed to be adopted for next year's cycle, and thus the one that would apply to the OP if he went back for upgrading) to know. I thought the language was unclear - that it seems possible that they're just going to use first-undergrad UGPA. I think grad school etc. is going to be a soft, but as I say I don't know about post-degree upgrading.

Still, I probably should've flagged Oz too. Good point.

And I guess in the interest of completeness, the schools with a holistic element to their admissions will consider upgrading, though it's hard to know to what extent.


letters picked without replacement from cccccdcwdwccwcc?
4/21
What is prob of picking 2 m when two letters picked without replacement from myymmmm?
10/21
What is prob of picking 2 g when two letters picked without replacement from {g: 4, d: 3}?
2/7
What is prob of picking 2 t when two letters picked without replacement from ijtiiti?
1/21
Calculate prob of picking 1 f and 2 d when three letters picked without replacement from {f: 2, d: 7}.
1/2
Calculate prob of picking 1 a and 1 r when two letters picked without replacement from {i: 5, a: 1, q: 1, d: 2, r: 1}.
1/45
Four letters picked without replacement from kkbkkdkbkdkbbekk. What is prob of picking 4 b?
1/1820
Two letters picked without replacement from ovawowwaoewvowoooe. Give prob of picking 1 o and 1 a.
14/153
Three letters picked without replacement fromQ:

notepad++ find number greater than a specific number

I have logs with some random numbers.
What I want to do is find numbers greater than a specific number, eg : find all number > 1234567.
Can anybody help?

A:

A weird regex (not sure it's really usefull) :
\d{8,}|123456[8-9]|12345[7-9]\d|1234[6-9]\d{2}|123[5-9]\d{3}|12[4-9]\d{4}|1[3-9]\d{5}|[2-9]\d{6}\b

It works only for the number 1234567 you have to modify it for another number.


locking moisture in and doesn't leave your hair greasy or heavy. Since it aids in locking moisture into hair it’s fantastic for keeping your hair protected against the weather.

You can use it alone or you can add it to your favorite conditioner to give you extra moisture. It’s also a great additive for shampoos and hair creams.

Protection Against Heat

Shea butter does not sit on the hair, instead it absorbs into the hair strand/shaft without leaving a greasy or heavy feel. However it does coat the hair shaft so that it is protected against damage from the heat tool being passed along the hair.

Apply in small amounts before blow drying and straightening natural hair.

Shield Against UVS

Shea butter is believed to have a low amount but sufficient SPF to protectthe setup and photos.

Here's how my setup looks with the new soft box. I'll be the first to admit I have no idea what I'm doing...

I'm using 8 60W light bulbs with the soft box: 5 on a stand behind the box, 1 on either side of the box and one just below the light box. I setup a glass shelf as the base of the soft box.

Believe it or not that's the PG Strike + Aile Pack in the box. You could probably fit two PG Strike Freedoms completely stretched out in Extreme Burst Mode without a problem!

Here are some comparison photos taken using my old setup and with the new box.

Before

After

Before

After

The soft light box practically eliminates blown out surfaces on glossy paint.

Before

After

Before

After

Before

After

Before

After

Before

After

Before

After

Before

After

Before

After

Overall I'm pretty happy with


know a lot of the people who read my blog noticed this stuff. They never called me out, judged or ridiculed. They guided me. And I learned.

The point is this. If it weren’t for all those bad projects, I would’ve never gotten to the good ones. (Halfway decent, at least.) I know the ugliness was aimed at bloggers who sell things- I guess they shouldn’t be able to earn money because they aren’t as experienced as others? Anybody can learn to sew. Not everyone can inspire.

Those blogs are popular because aside from their talent; they are fostering a love for sewing. Encouraging us to keep trying. They help us get better at the craft. That’s a beautiful thang!

I commend every single person who shares their sewing and craftingconfiguration options of the widget.
If no option is specified, returns a list describing all of
the available options for pathName (see Tk_ConfigureInfo for
information on the format of this list).  If option is specified
with no value, then the command returns a list describing the
one named option (this list will be identical to the corresponding
sublist of the value returned if no option is specified).  If
one or more option-value pairs are specified, then the command
modifies the given widget option(s) to have the given value(s);  in
this case the command returns an empty string.
Option may have any of the values accepted by the spinner
command.

 pathName down

 Derived classes may overload this method to specialize functionality.

 pathName up

 Derived classes may overload this method to specialize functionality.

COMPONENTS

Name:


it to the new .csproj format. You can read about the migration process in this blog post.
Visual Studio 2017 will also provide stable RTM tooling for .NET Core 1.0 (note that the tooling in Visual Studio 2015 is only in preview). There is another interesting blog post here which discusses the move to the new project format, Joe Morris from Microsoft confirms there are no plans to have VS 2015 support the build/project system.
Update
With the release of Visual Studio 2019, the latest .NET Core SDKs are not supported in Visual Studio 2015 or 2017. Here is the compatibility matrix:

she had learned, at least, to rate the virtue of a sense of humour.

If only she could make him laugh! Was it, she wanted Augusta to tell her, a trick that could be taught? She had taken a position (this is what she tried to explain to her 'sister'), she wasn't quite sure where, only it was in his way, and for whatever reason, she wasn't budging. Not that she didn't try to, only somehow she couldn't help it—she was stuck where she was. Augusta had responded that it wasn't only a question of making him laugh; it was also a question, of course, of laughing oneself. Annabella could not help but acknowledge the good sense of this remark, and yet, in spite of her best intentions, there


up was the note of rivalry aroused in her breast by the sound of her breathing. Her husband's state of excitement was undeniable. Annabella had slipped between his legs and was forced to stoop under his arms as he reached towards his sister. Their laughter had become hysterical; and Lord Byron, it seemed, satisfied with the results of his experiment, had been acting for some time on the preference it established. In any case, Annabella's patience for waiting her turn had come to an end.

She opened her eyes at last, but what she saw had little to do with what she had heard. 'Gussie' (Byron repeatedly invoked her pet name) was sobbing, and the deep breath of her passion was brought on only by tears. Her brother hadfriend, 'to wound her more hurtful in the long run than compelling her to adopt, in all their relations, so contorted a sense of being in the right, that it was almost impossible to keep it up for very long.' This little attempt at persuasion had perhaps a greater effect than she intended. Miss Montgomery was finally moved, not only to concede the point and to agree to the sending of the letter, but even to a brief faint show of tears, which she turned on her friend with an earnestness that suggested the force of self-reproach.

This was the letter Lady Byron sent her sister:

Before your confinement I would not risk agitating you. But having the satisfaction of knowing you are recovered, I will no longer conceal from


types of unconditioned responses may be observed suggesting an anxiety or fear. We suppose that, after injections of heparin, complicated biochemical modifications of the rat organism that cause harmonization of inhibiting and excitatory processes of central nervous system, take place.Blair's new focus: Global prosperity

Oct. 18, 2013
|

Former British Prime Minister Tony Blair shares his thoughts during an interview with The Des Moines Register on Thursday at the World Food Prize in Des Moines. / Christopher Gannon, The Des Moines Register

by Jennifer Jacobs, The Des Moines Register

by Jennifer Jacobs, The Des Moines Register

DES MOINES, Iowa -- Six years after his less-than-voluntary exit from Downing Street, Tony Blair's new career as an emissary for global peace and prosperity might be more satisfying than his decade-long stint as Britain's prime minister.

"I have to be careful here about that, but in some ways, I find what I do now more exciting and sometimes - always - more productive," Blair told The Des Moines Register in an interview Thursday.

Blair now crisscrosses the world


referred to Blair, who erroneously echoed claims that Saddam Hussein harbored weapons of mass destruction, as "Bush's poodle."

In June 2007, before the end of the full third term he had intended to serve, Blair tendered his resignation to the Queen.

Blair is still often dogged by protesters at public events back home.

"Happy, Tony?" someone tweeted to @tonyblairoffice this week. "We will not forget."

Asked during Thursday morning's panel discussion if he has experienced resentment, Blair smiled.

"Resentment generally? Yes. A fair amount of it," he said.

He went on to acknowledge that in foreign aid work "sometimes there's a feeling that people from the outside shouldn't tell us what to do." He also stressed that it's often the locals who have the best ideas.

In the Register interview, Blair said his work insuch as platinum. Nevertheless, oxygen may diffuse through the platinum bottom electrode to oxidize any silicon underlying the bottom electrode (e.g., a polysilicon plug or the silicon substrate). Although diffusion barriers may be incorporated to protect any underlying silicon from oxidation, these diffusion barriers are costly to integrate into the manufacturing process flow and are at any rate subject to breakdown during subsequent processing.
Use of ferro-electric materials introduces other special requirements for the process flows. One of the advantages of ferro-electric materials is the sharp switching characteristics of memory cells incorporating them, allowing their use in non-volatile memory applications. These switching characteristics, however, are sensitive to any variation in the thickness of the ferro-electric layer. Thus, the fabrication process should be such as to produce a ferro-electric layer


to be precipitated is provided within an enclosed space. Gases produced in the electroplating container upon the advance of the electroplating process are guided, together with the electroplating solution, into the enclosed space and applied there to the supply of metal in order to dissolve the latter. Then, the dissolved supply of metal is again added to the electroplating solution in the electroplating container. The apparatus required for carrying out of the process is, however, very expensive, because it must be gas-tight.
However, the discussed processes have the disadvantage that the plating solutions to be regenerated contain no additives, which, are generally required in order to control the physical-mechanical properties of the deposited metal layers. Such substances are predominantly organic substances.
It is only by these additives that the required
This is a test

So this includes the jQuery, Bootstrap, font-awesome and my personal stylesheet as you can see.
Question: What if someone goes to another page in my site for instance: /profileSettings.html
Will I have to load all the libraries again?
Sorry if this is a simple question but I am completely new to front-end development.
Thanks in advance

A:

As your code grows in size, you'll start using more sophisticated frameworks that may use something along the line of an MVC setup. Some of these frameworks allow you to define multiple "views"(think of them as HTML files for now) that are called from a


+ 9 = -0*f, w*f + 4*h = 0 for f.
3
Suppose -5*o + 13 = -4*o. Let k(a) = -a**3 + 13*a**2 - a + 15. Let d be k(o). Solve s + 2*u - 2 = u, 2*s = d*u - 16 for s.
-3
Let s be 4 + -7 + 1 + 0 + 4. Solve s*i - 2*u + 2 = 0, 0*u - 3 = -3*u for i.
0
Let x(d) = -d**3 + 8*d**2 + 4*d - 9. Let w be x(7). Suppose -6*i + w = -2*i. Suppose 3*g - i + 5 = 0. Solve v - 4 + 12 = -g*f, 0 = -4*v for f.
-2
Suppose 5*b = 4*r + 230 - 12, 224 = 5*b - 2*r. Let a be 2/7 +Q:

Antonym for "thimbleful"

What word can be used to describe a large quantity or amount in a way that it would sound like an antonym for "thimbleful". Preferably a word that rhymes with it or starts with "t". As in:
I had a thimbleful of patience and the task required "?antonym?".
I am looking for a word that has a highly positive connotation, and can be used in formal writing; in praise of someone.  I did not come across any entries in places like thesaurus.com for this word. Figurative usage does not seem to be defined even though examples are occasionally given.
Edit:
I chose "torrent" (plural "torrents"), hoping that it would be correct to use it as a unit for measuring something that is essentially limitless and unbounded, something


user, not just law enforcement. But
I suspect our FBI “expert” knows his.

But oddly when the FBI says “Apple” three times in a whiny voice, an iPhone
shows up in my shopping cart instead of an Android phone. My conspiracy theory
says the FBI is on the take from Apple, it’s the best advertising they have
right now.

------
cheeze
“It is difficult to get a man to understand something, when his salary depends
on his not understanding it.”

― Upton Sinclair

If I worked for Apple and had any part of this, I'd take his words as a
compliment.

~~~
cantrip
I think you could use this quote to justify both sides of the debate.

Unlike Google, which generates money from ads, Apple is a hardware company, so
data security is both economically viable and integral to their brand.

------
MatthiasP
FBI complaints are the bestQ:

CakePHP 3 : date comparison in view

I'm working on CakePHP 3.2.
I want to compare date from timestamp in database with isThisMonth() function of CakePHP.
I am listing products whose created date is within 1 month. It will show NEW badge with product.
This is what I have done in view
<?php $date = new DateTime($product->created);
      $date = $date->format('Y-m-d');
      if ($date->isThisMonth()): ?>   // error is pointing this line
          NEW
<?php endif; ?>

Here $product is an error item and created is a timestamp column in database.
But this gives error as
Call to a member function isThisMonth() on string

A:

Try adding this below $date = $date->format('Y-m-d');
$time = new Time($date);

then swap $date->isThisMonth()): with $time->isThisMonth()):
http://book.cakephp.org/3.0/en/core-libraries/time.html#comparing-with-the-present
include use Cake\I18n\Time;


white_lower, white_upper)
mask = cv2.bitwise_not(mask)

Now we fill find contours in this mask and select the largest one.
im, cnt, hierarchy = cv2.findContours(mask.copy(), cv2.RETR_EXTERNAL, cv2.CHAIN_APPROX_NONE)
largest_contour = max(cnt, key=lambda x:cv2.contourArea(x))
bounding_rect = cv2.boundingRect(largest_contour)

cropped_image = img[bounding_rect[1]: bounding_rect[1]+bounding_rect[3],
                bounding_rect[0]:bounding_rect[0]+bounding_rect[2]]

have earned their right to live in the city,” Keller begins to grapple out loud with the question of why Adam Smith’s “invisible hand” hasn’t already swept the homeless to somewhere else, out of sight.

AD

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“I want my parents when they come visit to have a great experience, and enjoy this special place,” he writes, before warning — in bold type — that “there is going to be a revolution” if the city doesn’t act soon.

“People on both sides are frustrated, and you can sense the anger,” he writes. “The city needs to tackle this problem head on, it can no longer ignore it and let people do whatever they want in the city. I don’t have a magic solution.

“It is a very difficult and complex situation,” Keller adds


for using the term riff raff. It was insensitive and counterproductive.”

AD

At the end of the day, however, Keller’s open-letter debacle might have been avoided if he had just heeded the advice of his Silicon Valley heroes.

“Be accountable,” Keller had written down during Startup School, quoting Watsi founder Chase Adam. “Be clear, assertive and thoughtful.”

Perhaps the best quote — the “shower epiphany” that slipped away from Keller — also came from Adam.

“Find something to work on that you care about more than yourself.”Q:

Representing a network in Python

I have a vertices such as dic = {'a': 0, 'b': 1, 'c': 2, 'd': 3, 'e': 4, 'f': 5, 'n':6, 'm':7, 'g':8} and i have two columns as follows represent the relationship between the vertices :
a a
b d
e f
c f
n f
m g

I want to associate each vertex in the first column with the corresponding vertex in the second column by an edge. So a with a is represent a loop. b with d is fine. e,c and n they are sharing the same vertex f. Instead  to say e with f, c with f and n with f we can say e, c and n with f.

A:

See:  https://www.python.org/doc/essays/graphs/
graph = {
    'a' : [ 'a' ],


'b' : [ 'd' ],
    'c' : [ 'f' ],
    'd' : [],
    'e' : [ 'f' ],
    'f' : [],
    'g' : [],
    'm' : [ 'g' ],
    'n' : [ 'f' ]
}

print [ vertex for vertex, edges in graph.items() if 'f' in edges ]

EDIT:
Ok, it sounds like you just want a function to build the graph from your given inputs?
Something like this:
def build_graph( vertices, edges ):
    graph = dict( (v, list()) for v in vertices.keys() )
    for a, b in edges:
        graph[ a ].append( b )
    return graph

If yourallying cry for parties like the ostracized far-right Alternative for Germany: “I absolutely want to empower other conservatives throughout Europe.”

Unaccustomed to such remarks from an ambassador of a close ally, the German government formally asked the U.S. government for clarification. Meanwhile, the State Department defended Grenell’s remarks. Martin Schulz, the former leader of the center-left SPD who was defeated by Merkel in 2017, called the comments “insufferable.” Schulz added: “Grenell isn’t behaving like a diplomat but instead like a right-wing extremist colonial governor.”

With an unmistakable style resembling Trump’s, Grenell has been an unabashed irritant to Germany ever since. Like Trump, he has openly criticized Germany on several fronts, especially for not spending enough on its own defense and falling far short on fulfilling pledges made to NATO to


distance to Grenell,” said Thomas Jaeger, a political scientist at the University of Cologne in Germany, referring to a 2018 Der Spiegel magazine article that said Grenell was largely ostracized by Germany’s political establishment.

“He had no qualms about putting the German government under pressure in public, which might not have always been the smartest thing to do,” Jaeger said. “But everyone knew Trump listened closely to him. I think they could have used that connection a lot better. In any case, Grenell has been highly effective in getting Germany to talk more about defense spending and about the Nord Stream 2 pipeline. The public opinion on those two issues has changed, and Grenell certainly had a role in that.”

It’s customary for ambassadors to refrain from commenting on successors,seat he currently holds has been represented by a New Democrat for more than three decades — John Holm held the riding for 19 years before Wilson.

What Wilson would do if he becomes the premier:

Establish mental health emergency rooms.

Cap the size of math and science classes in high schools.

Create a $15 minimum wage.

Lenore Zann

The longtime actor and world traveler has represented the riding of Truro-Bible Hill-Millbrook-Salmon River since 2009.

She was one of the only New Democrat backbenchers to survive the 2013 election.

Zann was arguably the most high profile non-cabinet minister in the previous legislature. According to the Internet Movie Database, IMDb, she has more than 100 film and TV credits to her name, including voice work on several animated series.

Not surprisingly, she has been one of her party's


someone i have never knowingly kissedhas a smoother tongue than i; has a taller steepleupon his behemoth of a cathedral;has a birthday which no mother has missedbecause her son is so grand. he reaches deeply into hispocket and pulls out a dimeso that her teeth can reach for another glass of wine:an indignation of a tombstone made of pearly glitz.

someone i have never willingly kissed shall meetmy tempers in a churchyard—a waking dawnwhich evaporates the holy water from the lawnand rains upon him to wash his muddy feet.

someone i have never knowingly kissed has left me deadwith a crown of forgotten kisses upon my head.

She said she would be there ten minutes ago; but—per usual—she had no sense of time. She was always worried about years rather thanhis eyes and fell right back to sleep. He thought his body would be able to help him get back into that glorious state again where he could hold her hand again and maybe even touch her lips with his.

i plan to reroute the paths of riversand the roads carved into mountain sidesby rains eroding stone.the course of the seasons will see my handand tremble, shift and take new realmsin different months. the sun and moonwill battle in the sky at my own willof change. i will shift the gleams of loveback in time; forward.


Juan Nunez-Iglesias, a fellow core-developer of scikit-image, and I gave
a scikit-image tutorial at SciPy 2014! I gave the first 2 hours (minus
a quick intro), and Juan gave the second 2 hours. Surprisingly, this was the
first tutorial at the (U.S.) SciPy conference (Emmanuelle Gouillart gave a
tutorial at EuroSciPy 2013).

Anyway, if anyone happens to have 4 hours to kill, here are links to the
videos:

But, even if don't want to watch these videos, the accompanying notebooks are
worth a look: notebooks on github. Currently, the scikit-image website
doesn't have any introductory tutorial docs, so this is probably the most
complete source for introductory material. I'd like to integrate these
notebooks as a user guide on the website, but that may take a bit of time.chose this technology to conduct the three-component condensation reaction. As a result, a similar yield was obtained under the same catalytic conditions when the reaction was carried out under microwave irradiation for just 2 h ([Table 1](#molecules-22-01503-t001){ref-type="table"}, entry 2). Then, we tried to optimize the reaction conditions under microwave heating. At first, various catalysts such as ZnCl~2~, FeSO~4~∙7H~2~O, CuBr~2~, and AlCl~3~ were evaluated ([Table 1](#molecules-22-01503-t001){ref-type="table"}, entries 3--6), and none of them exhibited a higher catalytic performance than FeCl~3~∙6H~2~O. Next, employing FeCl~3~∙6H~2~O as the catalyst, a series of additives were added and screened in order to improve the reaction yield ([Table 1](#molecules-22-01503-t001){ref-type="table"}, entries 7--12). Both BF~3~∙OEt~2~ and BBr~3~ caused no obvious enhancement of the reaction yield ([Table 1](#molecules-22-01503-t001){ref-type="table"}, entries 7 and 8). As TMS-X-type (X = Cl, I, OTf)


investigation for the development of medical therapies for hand, foot and mouth disease (HFMD). We anticipate that these important heterocyclic compounds may find their potent pharmaceutical applications after further exploration.

We gratefully acknowledge financial support from the National Natural Science Foundation of China (No. 21602022), the Open Project Program of Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province (No. ARRLKF15-01), Chengdu University New Faculty Start-up Funding (No. 2081915037) and the Open Project Program of Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department (No. 10Y201711).

**Sample Availability:** Samples of the compounds **4** and **6** are available from the authors.

Supplementary Files (Copies of ^1^H and ^13^C-NMR spectra of compounds **4** and **6**) are available online.

######

Click here for additional data file.

F.Z. conceived and designed the experiments; 9       ![](molecules-22-01503-i064.jpg)   ![](molecules-22-01503-i065.jpg)   ![](molecules-22-01503-i066.jpg)   83
  10      ![](molecules-22-01503-i067.jpg)   ![](molecules-22-01503-i068.jpg)   ![](molecules-22-01503-i069.jpg)   88
  11      ![](molecules-22-01503-i070.jpg)   ![](molecules-22-01503-i071.jpg)   ![](molecules-22-01503-i072.jpg)   87
  12      ![](molecules-22-01503-i073.jpg)   ![](molecules-22-01503-i074.jpg)   ![](molecules-22-01503-i075.jpg)   82

^a^ Reaction conditions: **1** (0.5 mmol), **2** (0.5 mmol), **5a** (0.75 mmol), FeCl~3~∙6H~2~O (0.05 mmol) and TMSBr (0.5 mmol) in CH~3~CN (3.0 mL) at 90 °C for 2 h under microwave irradiation (sealed vessel at fixed power, 30 W); ^b^ Isolated yield.


planet (or brown dwarf) material to the core and around it may have several effects. First, the low entropy material can absorb heat, and may reduce for a short period of time the stellar luminosity (Harpaz & Soker 1994). If the material reaches the core, or close to it, the release of gravitational energy and nuclear burning of the fresh hydrogen-rich material may lead to stellar expansion and enhanced mass loss rate (Siess & Livio 1999a,b). Recently, Retter & Marom (2003) proposed that three planets which deposited gravitational, and then nuclear, energy into their parent RGB star, along the calculations of Siess & Livio (1999b), with about a month delay from one planet to the next, can account for the erupting of V838 Mon. Second, the high specific$M_1$ are the luminosity, radius, and mass of the giant (RGB or AGB star), respectively, $M_{\rm {env}}$ is the giant’s envelope mass, and $\tau_{\rm ev}$ is the evolution time on the upper AGB or RGB.

Influencing the Horizontal Branch Morphology
============================================

After RGB stars ignite helium in their core they move to the horizontal branch (HB) on the HR diagram. Stars which lose more mass on the RGB become bluer (hotter) HB stars. The HB morphologies, i.e., the distribution of stars on the HB of a stellar system, differs substantially from one globular cluster to another. It has long been known that metallicity is the main factor which determines the location of HB stars on the HR diagram. Metallicity is the [*first parameter*]{}. For more than 30 years, though, it has


cohort registry that collects questionnaire responses from WWE upon 5 visits. The questionnaire has been used in a previous preliminary study \[[@pone.0189497.ref016]\]. Visits were selected to match regular maternal check-up schedules, in order to increase compliance. The 1^st^ visit occurred in early pregnancy, the 2^nd^ visit was at 12 and 13 weeks of gestational age (GA) follow-up, and the 3^rd^ visits recorded responses at 28--32 weeks GA. Following delivery, the 4^th^ questionnaire responses was recorded 7 days after birth, while the last questionnaire was recorded 1 year after birth. During the course of data collection, 50 mothers had more than one pregnancy. We included multiple pregnancies because women's profile (Age, parity, AED profile, seizure event/frequency, birth outcomes) differed enough to be considered independently.

Study sample {#sec004}
------------

TREP is a registry                                                                      Category      Malformation\   Malformation\   *aOR*[^*c*^](#t004fn005){ref-type="table-fn"}^,^[^*d*^](#t004fn006){ref-type="table-fn"} *(CI95%)*   P-value


Registry of Epilepsy and Pregnancy* (TREP) questionnaire for pregnant women with epilepsy.

Translated into Mandarin from the EURAP questionnaire (see [S1 Fig](#pone.0189497.s001){ref-type="supplementary-material"}).

(PDF)

######

Click here for additional data file.

###### Fetal malformation listed by cases (N = 16).

*Notes*. ^a^ MCM = major congenital malformation, ^b^ PDA = Patent Ductus Arteriosus, ^c^ DORV = Double outlet right ventricle. ^*d*.^ *Live Birth*: *Y = live birth*, *N = still birth*, *a = aborted*. ^*e*.^ *Ultrasound Screening Performed*: *Y = Yes*, *N = No*, *n/a = not available*. ^*f*.^ *Positive Findings*: *5/9 = 55*.*6% accuracy*. ^g.^ Means reported for live births only. \*, \*\*, \*\*\*, †, ‡, indicate concurrent maternal complications ([S2 Table](#pone.0189497.s004){ref-type="supplementary-material"}).

(PDF)

######

Click here for additional data file.

###### Obstetric complications listed by cases (N = 14).

*Notes*. ^a.^ CS = Cesarean section, ^b.^ PPROMless efficient mechanisms for supporting oxidative energy production. The overall goal is to intervene via pharmacologic and genomic manipulation of the metabolic adaptations that occur during compensated and later stage, decompensated hypertrophy in rat hearts. Our experimental aims will 1) explore the energetic implications of such adaptive changes in intermediary metabolism by pharmacologically augmenting pyruvate entry into the TCA cycle at PDH; 2) elucidate the link between increased OMC activity, a protein transferring cytosolic reducing equivalents into the mitochondria, and alleviation of the cytosolic redox load due to uncoupling of glycolytic rate from glucose oxidation in the hypertrophic heart; 3) exploit our newly developed advances in the efficiency of cardiac-specific in vivo gene transfer to elucidate the regulatory role of OMC in providing TCA cycle intermediates via induced


traveling with her. “We expect all of our partners who share that concern, as these countries certainly do, to stay as focused as they can, and to do everything within reason that will help to implement these sanctions.”

Last week, the departing chief of Israel’s intelligence agency, Meir Dagan, said that Iran would not be able to produce a nuclear weapon before 2015 because of “measures that have been deployed against them.” American officials have also suggested that technical complications may have slowed Iran, which was once seen as being only a year or two away from a bomb.Q:

Com DLL Gives Exception .NET 4 only

A COM DLL works in .NET 3.5 SP1, but gives exception in .NET 4.0
The full error is

Retrieving the COM class factory for component with CLSID {B229C879-1B52-4DE9-A42B-75C415EA1EBC} failed due to the following error: 8007045a A dynamic link library (DLL) initialization routine failed. (Exception from HRESULT: 0x8007045A).

If I change the target framework to 3.5 it works, back to 4.0 it doesn't.
The application is a desktop WPF app.
How can this be solved?

A:

The DllMain() method of the DLL returned FALSE. You'll need to use a debugger to find out why.  Set a breakpoint on it and enable unmanaged debugging with Project + Properties, Debug tab.  Source code and a .pdb file for the DLL is required.


tmpdir.join("default").mkdir()
    with tmpdir.join("default").join("color").open("w") as f:
        f.write("#8ab6d2")

    db = Database([tmpdir.join("default")], tmpdir.join("cache.sqlite3"))
    list_ = next(db.lists())

    assert list_.colour == "#8ab6d2"

def test_list_colour_cache_invalidation(tmpdir, sleep):
    tmpdir.join("default").mkdir()
    with tmpdir.join("default").join("color").open("w") as f:
        f.write("#8ab6d2")

    db = Database([tmpdir.join("default")], tmpdir.join("cache.sqlite3"))
    list_ = next(db.lists())

    assert list_.colour == "#8ab6d2"

    sleep()

    with tmpdir.join("default").join("color").open("w") as f:
        f.write("#f874fd")

    db = Database([tmpdir.join("default")], tmpdir.join("cache.sqlite3"))
    list_ = next(db.lists())

    assert list_.colour == "#f874fd"

def test_list_no_colour(tmpdir):
    tmpdir.join("default").mkdir()

    db = Database([tmpdir.join("default")], tmpdir.join("cache.sqlite3"))
is that people turn up the volume to block out annoying background noise. Noise-isolating and noise-cancelling headphones help to remove the background noise so you don’t turn the volume to dangerous levels.

Alternatives to Headphones

Turn your hearing aids into built-in headphones.

If you were fit with two individual Hearing aids, they were created to interact as a single unit to deliver a more cohesive technology. Your units speak to one another, so when you make an adjustment for one, the other adjusts automatically. And with wireless Bluetooth® technology, you can stream audio from your television, calls from your cell phone or landline, or music from your computer with minimal effort.

Made for iPhone® Hearing Aids

Many hearing aids offer a wireless streaming function that pushes phone calls, music, video, and other audio


Q:

Wrong levels after storing character as factor

In my dataframe df I have Likert-Scale items coded 0-4. After importing these from the raw file into R, they were stored as characters.
I then created a list with boolean indicating whether each variable was a character, then used lapply to change it to factor.
i <- sapply(df, is.character)
df[i] <- lapply(df[i], as.factor)

When looking at some of the now factor variables (all are originally coded as 0-4), I get:
df$reactance1
[1] 3   3   4   3     2   4   1   4   3   3   1   1   4   3   4   3   4   4
Levels:src="<?php echo $mp4URL; ?>" type="video/mp4">
        <?php
        }
        echo t("Your browser doesn't support the HTML5 video tag.");
        ?>
    </video>
<?php
}
?>
</div>


and we consider *ω*~*c*~=*ω*~*a*~.

We use the Heisenberg equation of motion $\documentclass[12pt]{minimal}
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  on the distance between cavity *c* and cavity *a* \[[@CR26]\] (also the coupling strength decreases exponentially with increasing the distance of the two cavities). Here, we expect the coupling strength $\documentclass[12pt]{minimal}
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coupled to an auxiliary cavity with high-quality factor. We investigate the optical bistability under different parameter regimes such as the coupling strength *J* between the two cavities and the decay rate ratio *δ* of the two cavities in the system. The optical bistability can be adjusted by the pump field driving the optomechanical cavity, and the intracavity photon number in the two cavities is determined by the coupling strength *J*. Further, we have also demonstrated how to control the FWM process in the photonic-molecule optomechanical system under different driving conditions (the red sideband and the blue sideband) and different parameter conditions (the coupling strength *J* and the ratio *δ*). Numerical results show that the FWM process can be controlled with such parameters. These results are beneficial for betterLaboratory tests used in diagnosis and treatment of AIDS.
Detailed knowledge of the structure of the human immunodeficiency virus (HIV) triggered a rapid development of methods for diagnosing the infection. The enzyme-linked immunoadsorbent assay (ELISA) determining the presence of antibodies to the protein components of the virus in toto is highly sensitive and provides thus the basic screening approach. It is however somewhat less specific and therefore all positive results are verified by the Western blot method which detects individual HIV proteins and possesses a 99.9% specificity. In sporadic cases the latent period between HIV infection and the possibility to establish antibody response may extend to six months and even longer. The polymerase chain reaction (PCR) revealing the presence of DNA HIV in infected cells is suitable for detecting