PRL-specific RNA sequences. The striking effect of BrdUrd on PRL synthesis is being utilized to obtain information on hormone receptor interactions with specific DNA binding sites. The recently observed BrdUrd-induced amplification of the PRL gene will help elucidate the mechanism of turning the switch "on" or "off" for the process of gene amplification in this system. As drug-induced amplification seems limited within the 20 kilobase segment within and around the PRL gene-coding sequence, these results suggest initiation and termination of such preferential DNA replication site(s) within this region that selectively respond to the drug BrdUrd. Identification of this site(s) will be of significant interest for the understanding of gene amplification in eukaryotic cells. (C)million in 16 days at AP Box office, and was expected to reach the 500 million mark worldwide. The film completed a 25-day run in early February 2014, collecting more than 380 million at the AP Box office. The film collected 393.4 million at the AP Box office and 471 million worldwide during its lifetime, and was declared as one of the Ram Charan's biggest hits.

 Overseas
According to Taran Adarsh, the film collected 14.6 million in its opening weekend in the United States. In its first five days in the US, the film collected 22 million. By the end of its second week, the film's performance was disappointing; and it only collected a total of $330,000 as of 20 January 2014, while 1: Nenokkadine'' collected $1 million


One of the major challenges with the SONY Alpha System has been the lack of information about up and coming products. The biggest knock has been, just like nuclear weapons, that SONY will neither confirm or deny where they are going with their camera line. It is complete supposition by the buying public.

I have to say, for me, as well as many others ... this has cost them dearly in NEW business sales as well as keeping the bridge up between older, more dedicated users.

I can say I am not an aficionado of this particular business plan. Personally, I believe it has more negatives about it than many, if any, positives. If anything, it is silly to think that Canon or Nikon would be that much more benefited<cc:java>
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 with analytic singularities
---

[^1]

Introduction
============

We say that a plurisubharmonic (psh) function $u$ on a complex manifold $X$ has [*analytic singularities*]{} if locally it can be written in the form $$\label{as}
  u=c\log|F|+b,$$ where $c\geq 0$ is a constant, $F=(f_1,\dots,f_m)$ is a tuple of holomorphic functions, and $b$ is bounded. For instance, if $f_j$ are holomorphic functions and $a_j$ are positive rational numbers, then $\log(|f_1|^{a_1}+\cdots +|f_m|^{a_m})$ has analytic singularities.

By the classical Bedford-Taylor theory, [@BT1; @BT2], if $u$ is of the form , then in $\{F\neq 0\}$, for any $k$, one can define a positive closed current $(dd^c u)^k$ recursively as $$\label{snabel}
(dd^c u)^k:=dd^c\big (u(dd^c u)^{k-1}\big ).$$ It was shown in [@AW] that $(dd^cu)^{k}$ has locally finite mass near $\{F=0\}$ for any $k$ and that the natural extension ${{\bf 1}}_{\{F\neq 0\}}(dd^cu)^{k-1}$ acrossdecreasing sequence of psh functions converging pointwise to $u$, then $(dd^cu_j)^k\to
(dd^cu)^k$ weakly. Moreover, a general psh function $u$ is said to be in the domain of the Monge-Ampère operator $\mathcal D(X)$ if, in all open sets $\mathcal U\subset X$, $(dd^cu_j)^n$ converge to the same Radon measure for all decreasing sequences of smooth psh $u_j$ converging to $u$ in $\mathcal U$. The domain $\mathcal D(X)$ was characterized in [@Bma; @Bajm]; in case $X$ is a hyperconvex domain in ${\mathbb{C}}^n$ $\mathcal D(X)$ coincides with the Cegrell class, [@C].

In this paper we study continuity properties of the Monge-Ampère operators $(dd^c u)^k$ defined by . It is not hard to see that general psh functions with analytic singularities do not belong to $\mathcal D(X)$, cf. Examples  \[skola\] and  \[dagis\] below, and therefore we


do not have continuity for all decreasing sequences in general. Our main result, however, states that continuity does hold for a large class of natural approximating sequences. It thus provides an alternative definition of $(dd^cu)^k$, and at the same time gives further motivation for that this Monge-Ampère operator is indeed natural.

\[conv\] Let $u$ be a negative psh function with analytic singularities on a manifold of dimension $n$. Assume that $\chi_j(t)$ is a sequence of bounded nondecreasing convex functions defined for $t\in(-\infty,0)$ decreasing to $t$ as $j\to\infty$. Then for every $k=1,\dots,n$ we have weak convergence of currents $$\big (dd^c(\chi_j\circ u)\big )^k\longrightarrow(dd^cu)^k$$ as $j\to\infty$.

For instance, we can take $\chi_j=\max(t, -j)$ or $\chi_j=(1/2) \log( e^{2t}+1/j)$. Applied to $u=\log |F|$ and $\chi_j=(1/2)\log( e^{2t}+1/j)$ Theorem  \[conv\] says that $$\big(dd^c (1/2)\log (|F|^2+1/j)\big )^k \tois an $\omega$-psh function with analytic singularities, we can define a global positive current $(\omega + dd^c \varphi)^k$, by locally defining it as $(dd^c (g+\varphi))^k$, see Lemma  \[niko\]. We will prove the following formula for the total Monge-Ampère mass:

\[tmass\] Let $\varphi$ be an $\omega$-psh function with analytic singularities on a compact Kähler manifold $(X,\omega)$ of dimension $n$. Let $Z$ be the singular set of $\varphi$. Then $$\label{north}
\int_X(\omega+dd^c\varphi)^n
      =\int_X\omega^n
      -\sum_{k=1}^{n-1}\int_X{{\bf 1}}_Z(\omega+dd^c\varphi)^k
         \wedge\omega^{n-k}.$$

In particular, $$\label{tvol}
   \int_X(\omega+dd^c\varphi)^n\leq\int_X\omega^n.$$

Let $\varphi$ be a general $\omega$-psh function such that the Bedford-Taylor-Demailly Monge-Ampère operator $(\omega +dd^c
\varphi)^n$ is well-defined; if $\varphi$ has analytic singularities, this means that the singular set has dimension 0. Then it follows from


Stokes’ theorem that equality holds in .

To see that in general there is not equality in consider the following simple example:

\[ormar\] Let $X$ be the projective space $\mathbb P^n$ with the Fubini-Study metric $\omega$ and let $n\ge 2$. Define $$\varphi\big ([z_0:z_1:\ldots:z_n]\big ):=\log
\Big (\frac{|z_1|}{|z|}\Big),\ \ \
     z\in\mathbb C^{n+1}\setminus\{0\}.$$ Since $(dd^c\log|z_1|)^n=0$ in $\mathbb C^{n+1}$, cf. , it follows that $(\omega+dd^c\varphi)^n=0$ on  $\mathbb P^n$.

In Section \[kahl\] we provide a geometric interpretation of Theorem \[tmass\] which in particular shows that inequality in is not an “exceptional case”.

The paper is organized as follows. In Section \[sec3\] we prove a continuity result for currents of the form $$u\,dd^cv_1\wedge\dots\wedge dd^cv_k,$$ where $u$ is psh and $v_1,\dots,v_k$ are locally bounded psh, defined by Demailly [@D], cf. . In Section  \[sec4\] we prove Theorem \[conv\] for functionsavailable at [http://gamma.im.uj.edu.pl/$\widetilde{\phantom{p}}$blocki]{}.

, [*On the definition of the Monge-Ampère operator in $\mathbb C^2$*]{}, Math. Ann. 328 (2004), 415–423.

, [*The domain of definition of the complex Monge-Ampère operator*]{}, Amer. J. Math. 128 (2006), 519–530.

, [*A note on maximal plurisubharmonic functions*]{}, Uzbek Math. J. 1 (2009), 28–32.

, [*Monge-Ampe‘re equations in big cohomology classes*]{} Acta Math.  [205]{}, (2010), 199–262.

, [*The general definition of the complex Monge-Ampère operator.*]{} Ann. Inst. Fourier (Grenoble) 54 (2004), no. 1, 159-–179.

, [*Potential theory in several complex variables*]{}, lecture notes, 1989, available at [http://www-fourier.ujf-grenoble.fr/$\widetilde{\phantom{p}}$demailly]{}.

, [*Regularization of closed positive currents and intersection theory*]{}, J. Alg.Geom. 1 (1992), 361–409.

, [*Monge-Ampère operators, Lelong numbers and intersection theory*]{}, Complex analysis and geometry, 115–193, Univ. Ser. Math. Plenum, New York, 1993.

, [*Complex Analytic and Differential Geometry*]{}, 1997, available at [http://www-fourier.ujf-grenoble.fr/$\widetilde
{\phantom{a}}$demailly/books.html]{}

, [*Pseudo-effective line bundles on compact Kähler manifolds*]{}, Internat. J. Math. 12 (2001), 689–741.

, [*Segre numbers and hypersurface singularities*]{}


images of Matthew Modine and Joseph Gordon Levitt in The Dark Knight Rises? Can Jonathan Nolan comment on that film and when might we see the next trailer? Read about that and more in today’s Superhero Bits. Read More »

What does James McAvoy have to say about a sequel to X-Men: First Class? Did Michael Shannon reveal any General Zod details from Man of Steel? Want to hear what Rhys Ifans‘ The Lizard might sound like in The Amazing Spider-Man? Can we finally put the question of Captain America 2‘s timeline to bed? How can you win a trip to the Ghost Rider: Spirit of Vengeance world premiere? Read about this and much more in today’s Superhero Bits. Read More »

What Thor 2 secrets did Tom Hiddleston andAn open trial of 'grief-help': a cognitive-behavioural treatment for prolonged grief in children and adolescents.
In the past years, there is growing recognition of a syndrome of disturbed grief referred to as prolonged grief disorder (PGD). Although mostly studied in adults, clinically significant PGD symptoms have also been observed in children and adolescents. To date, no effective treatment for childhood PGD yet exists. We recently developed a nine-session cognitive-behavioural treatment for childhood PGD combined with five sessions of parental counselling. In the current article, we present outcomes of treatment of 10 consecutive children and adolescents turning to our university clinic with elevated PGD symptoms as their primary problem and main reason to seek therapy. Patients were significantly improved at post-treatment, with large improvements in self-rated PGD and post-traumatic stress


surround, support, and protect the oocyte \[[@B16]\]. Follicles within the avian ovary are ordered progressively by size from many follicles \<1 mm in diameter to the pre-ovulatory or F1 follicle at around 40 mm \[[@B17]\]. Follicles can be grouped into 2 basic types, white follicles, which range from 1--7 mm in diameter, and yellow follicles, from approximately 8--40 mm, which are distinguishable by the deposition of yolk, that gives them their colour, and the increased vascularisation needed to support their growth \[[@B17]\]. Most follicles will not grow sufficiently to undergo ovulation and the majority \<8 mm will become atretic. Normally under appropriate endocrine conditions following ovulation a follicle from the 6--8 mm pool is recruited into the pre-ovulatory hierarchy \[[@B18],[@B19]\]. Once recruited and unless gonadotrophin support is removed these follicles are highly likely topoints in 35 games. He's the only Electrician with more than 10 goals.

"He's in his third year and has adapted to more of a leadership role," Nebel said. "He has good speed, good hands and a good shot."

Forward Eric Chapman is next on the scoring list with two goals and 24 assists for 26 points, with forward Nicholas Cammarata third at five goals and 13 assists for 18 points.

The Electricians have picked up forward Dustin Goupille from the Negaunee High School hockey team for more of a scoring punch. In five games with the Electricians, Goupille has recorded two goals and three assists.

"He provides leadership, energy and competitive skills," Nebel said of Goupille, who scored six goals in one game for the Miners against Lapeer earlier this season.


its definition of "curtilage".

In UK listed-building legislation
The concept of curtilage is relevant to town and country planning in the United Kingdom, particularly as it relates to listed building legislation. The consideration afforded to a listed building may extend to other structures or landscape within the curtilage of the primary structure, if the item(s) in the curtilage is old enough, and physically attached to the main building or otherwise important to the setting of the structure. Current legislation uses a cut-off date of 1947, so that later additions, while they may be within the curtilage, are not included in the listing designation.

The listing of a building or structure does not define its specific curtilage, and so this can become a matter of interpretation and contention. Various factors needOne Pan Sesame And Lemon Chicken Recipe

03/10/2013 16:54
|
Updated
22 May 2015

parentdish.co.uk
Parentdish UK

One pan sesame and lemon chicken

This easy and relaxed dish has a bit of everything for everyone. It's great for entertaining with family and friends and easily doubled up to serve more if you're caught out with more guests than you planned for.

2. Lay the chicken in a large roasting tin and scatter the butternut squash and garlic cloves around it. Drizzle over the oil and squeeze the juice from the lemon quarters, tucking the empty shells in and around the chicken and squash.

3.Roast in the oven for 40 minutes, until the chicken is crisp and the squash in soft and lightly caramelised. If your chicken thighs are particularly large you may need to increase cooking by 10


minutes.

4. Blanch the Tenderstem in boiling water for two minutes, drain and set aside. Remove the tray from the oven, stir through the blanched Tenderstem, coating it well in the lemony juices.

5. Drizzle the honey all over and sprinkle on the sesame seeds. Return to the oven for a further 10 minutes until the chicken is sticky and golden. Serve immediately with plenty of rice and perhaps a little soy sauce.the asymptotic covariance matrices in our CLTs are random (as said before, they depend on the random variable $Z_\infty$). This is why we do not use the simple convergence in distribution, but we employ the notion of stable convergence, which is, among other things, essential for the considered statistical applications. Moreover in [@mok-pel], the authors find two different convergence rates, depending on the two different step-sizes, while, as already said, we find a common convergence rate also in some cases with $\nu\neq \gamma$.\
Summing up, this work complete the convergence results obtained in [@ale-cri-ghi-MEAN; @ale-cri-ghi] for the stochastic processes of the personal inclinations $Z^j=(Z_{n,j})_n$ and of the empirical means $\overline{X}^j=(\overline{X}_{n,j})_n$, and it extend them to the weighted empirical means $N^j=(N_{n,j})_n$. However the main focus here concerns the new decomposition employed


for the analysis of the asymptotic behavior of the pair $(\mathbf{Z}_n,\mathbf{N}_n)$, that, among other things, allows us to solve the research question arisen in [@ale-cri-ghi-MEAN] regarding the statistical test on $W$ in the case $\gamma< 1$. Thus, in what follows, we will go fast on the point in common with [@ale-cri-ghi-MEAN; @ale-cri-ghi], while we concentrate on the novelties.\
The rest of the paper is organized as follows. In Section \[section\_model\] we describe the notation and the assumptions used along the paper. In Section \[section\_main\_results\] and Section \[section\_statistics\] we illustrate our main results and we discuss some possible statistical applications. An interesting example of interacting system is also provided in order to clarify the statement of the theorems and the related comments. Section \[section\_proofs\_1\] and Section \[section\_proofs\_statistics\] contain the proofs$$q_{n,n}=1-\frac{\sum_{l=1}^{n-1}a_l}{\sum_{l=1}^na_l}=
    1-\left(1-\frac{1}{n}\right)^{\delta}= \delta n^{-1}+O(n^{-2}),$$ so that we have $\nu=1$ and $q=\delta>0$;

-   $\sum_{l=1}^na_l=\exp(b n^\delta)$ with $b>0$ and $\delta\in(0,1/2)$, which brings to $$a_n=\exp(b n^\delta)-\exp(b (n-1)^\delta)$$ and $$\begin{split}
    q_{n,n}&=1-\frac{\sum_{l=1}^{n-1}a_l}{\sum_{l=1}^na_l}=
    1-\exp\left[b\left((n-1)^{\delta}-n^{\delta}\right)\right]\\
    &=
    b
    n^{\delta}\left( 1- (1-n^{-1})^\delta \right)
    +O\left(\, n^{2\delta}( 1-(1-n^{-1})^\delta )^2 \,\right)
    =b n^{\delta}\left( \delta n^{-1}+O(n^{-2}) \right)+O(n^{-(2-2\delta)})\\
    &=b \delta n^{-(1-\delta)}+O(n^{-(2-\delta)})+O(n^{-(2-2\delta)})=
    b \delta n^{-(1-\delta)}+O(n^{-2(1-\delta)}),
    \end{split}$$ so that $\nu=(1-\delta)\in (1/2,1)$ and $q=b\delta >0$.

To ease the notation, we set $\widehat{r}_{n-1}:=cn^{-\gamma}$ and $\widehat{q}_{n,n}:=qn^{-\nu}$, so that condition can be rewritten as $$r_{n-1}=\widehat{r}_{n-1}+O\left(\frac{1}{n^{2\gamma}}\right)\qquad\hbox{
and }\qquad
q_{n,n}=\widehat{q}_{n,n}+O\left(\frac{1}{n^{2\nu}}\right).$$

For the CLTs provided in the sequel, we make also the following assumption:

\[ass:case1\] When $\gamma=1$, we assume the condition $c>1/[2(1-\mathcal{R}e(\lambda^*))]$,


of $N\geq 2$ interacting reinforced stochastic processes. However, it is worth to note that Theorem \[th-as-synchro\], and the consequent limit , hold true also for $N=1$. Moreover, statements (d) and (e) of Theorem \[clt-Y\] with $N=1$ are true and they correspond to [@ale-cri-ghi-MEAN Theorems 3.2 and 3.3]. Finally statements (a), (b) and (c) of Theorem \[clt-Y\] with $N=1$ (and so without the condition on $\lambda^*$) can be proven with the same proof provided in the sequel (see the following Remark \[rem-N=1-bis\]).

We conclude this section with the example of the “mean-field” interaction.

\[esempio\] The mean-field interaction can be expressed in terms of a particular weighted adjacency matrix $W$ as follows: for any $1 \leq j_1, j_2 \leq N$ $$\label{medione}
w_{j_1,j_2} = \frac{\alpha}{N} + (1-\alpha)\delta_{j_1,j_2} \qquad
\mbox{with }\alpha\in [0, 1],$$ where $\delta_{j_1,j_2}$variables $Z_{n,j}$, nor the knowledge of the initial random variables $\{Z_{0,j}:\, j\in V\}$ and nor of the exact expression of the sequence $(r_n)_n$. They are based on the weighted empirical means of the random variables $X_{n,j}$, that are typically observable.\
The second result stated in this section can be employed for the construction of asymptotic critical regions for statistical tests on the weighted adjacency matrix $W$ based on the weighted empirical means (given the values of $\gamma,\,\nu,\,c$ and $q$). In particular, we point out that in our previous work [@ale-cri-ghi-MEAN] we succeeded to provide a testing procedure based on the standard empirical means only for the case $\gamma=1$; while we announced further future investigation for the case $1/2<\gamma<1$. In the present work we face and solve this issue, providing


&\hbox{if } \nu=1\;\hbox{and } q=\gamma-(2u)^{-1}>1/2,\\
O\left(n^{-2\gamma u+1}\right)
\qquad &\hbox{if } \nu=1\;\hbox{and } q>\max\{1/2,\gamma-(2u)^{-1}\}\,.
\end{cases}
\end{split}$$ For the second term, we apply Lemma \[lemma-tecnico-O\] together with Lemma \[lemma-tecnico-G\] so that we get:

Case $\nu<\gamma$

:   We have $G_{k+1,n-1}(c\alpha_j,q)=O\big(n^{-(\gamma-\nu)}|F^{\nu}_{k+1,n-1}(q)|+
      k^{-(\gamma-\nu)}|F^{\gamma}_{k+1,n-1}(c\alpha_j)|\big)$ by means of Lemma \[lemma-tecnico-G\], and so we find $$\begin{split}
    &\sum_{k=m_0}^{n-1} O\left((\Gamma^{21}_{k+1,n-1})^{2u}\right)
    =\sum_{j\in J,j\neq 1} I_{\{2\in I_j\}}
    O\left(\sum_{k=m_0}^{n-1}\frac{1}{k^{2\gamma u}}|G_{k+1,n-1}(c\alpha_j,q)|^{2u}\right)
    =
    \\
    &\sum_{j\in J,j\neq 1} I_{\{2\in I_j\}}
    O\left(
    n^{-2(\gamma-\nu)u}
    \sum_{k=m_0}^{n-1}\frac{1}{k^{2\gamma u}}|F^\nu_{k+1,n-1}(q)|^{2u}
    +
    \sum_{k=m_0}^{n-1}\frac{1}{k^{4\gamma u-2\nu u}}|F^\gamma_{k+1,n-1}(c\alpha_j)|^{2u}
    \right)\,,
    \end{split}$$ where, by Lemma \[lemma-tecnico-O\], the first term is $O(n^{-4\gamma u +2\nufor $x=q$ or $x\in\{c\alpha_j:\, j\in J,\,j\neq 1\}$ $$\sum_{k=m_0}^{n-1}
    \frac{1}{k^{2\gamma u}}|F^{\gamma}_{k+1,n-1}(x)|^{2u}
    =
    \begin{cases}
    O\left(n^{-\gamma(2u-1)}\right)
    \qquad &\hbox{if } 1/2<\nu=\gamma<1,\\
    O\left(n^{-2a_xu}\right)
    \qquad &\hbox{if } \nu=\gamma=1\;\hbox{and } 1/2< a_x<1-(2u)^{-1},\\
    O\left(n^{-2u+1}\ln(n)\right)
    \qquad &\hbox{if } \nu=\gamma=1\;\hbox{and } a_x=1-(2u)^{-1},\\
    O\left(n^{-2u+1}\right)
    \qquad &\hbox{if } \nu=\gamma=1\;\hbox{and } a_x>1-(2u)^{-1}
    \end{cases}$$ and so, setting $x^*:=\min\{q,ca^*\}$, we can write $$\sum_{k=m_0}^{n-1} O\left((\Gamma^{21}_{k+1,n-1})^{2u}\right)
    =\sum_{j\in J,j\neq 1} I_{\{2\in I_j\}}
    \begin{cases}
    O\left(n^{-\gamma(2u-1)}\right)
    \qquad &\hbox{if } 1/2<\nu=\gamma<1,\\
    O\left(n^{-2x^*u}\right)
    \qquad &\hbox{if } \nu=\gamma=1\;\hbox{and } 1/2< x^*<1-(2u)^{-1},\\
    O\left(n^{-2u+1}\ln(n)\right)


j=1
\\
&\lambda_{j}\widehat{r}_{k-1}G_{k+1,n-1}(c\alpha_j,q)+
\left(\widehat{q}_{k,k}-\widehat{r}_{k-1}g(\lambda_{j})\right)F^{\nu}_{k+1,n-1}(q)
\;\hbox{for } j\geq 2\,,
\end{cases}
\end{split}$$ where $g$ is defined in , and so, for each $j\geq 2$, we have $g(\lambda_j)=\lambda_j$ when $\nu<\gamma$, while $g(\lambda_j)=0$ when $\nu\geq\gamma$.\
Here, for each of the six cases $(i)-(vi)$ listed in Lemma \[conv-general-sum\], we compute the limit $$d^{j_1(i_1),j_2(i_2)}\ =\
\lim_{n}t_n(J(I))^2
\sum_{k=m_0}^{n-1}d_{k,n}^{j_1(i_1)}d_{k,n}^{j_2(i_2)}\,.$$ For all the computations, we make the assumptions stated in Section \[section\_model\] and we use Lemma \[lemma-tecnico\_2-nuovo\] and Lemma \[lemma-tecnico-G\].

Case $(i)$

:   Take $\nu<\gamma$, $j_1,j_2\in\{2,\dots, N\}$ and $i_1=i_2=1$. We have $$\begin{split}
    \lim_n t_n(J(I))^2
    \sum_{k=m_0}^{n-1}d_{k,n}^{j_1(i_1)}d_{k,n}^{j_2(i_2)}
    &=
    \lim_n
    n^{\gamma}\sum_{k=m_0}^{n-1}\widehat{r}_{k-1}^2
    F^{\gamma}_{k+1,n-1}(c\alpha_{j_1})F^{\gamma}_{k+1,n-1}(c\alpha_{j_2})
    \\
    &=
    c^2
    \lim_n
    n^{\gamma}\sum_{k=m_0}^{n-1}
    k^{-2\gamma} F^{\gamma}_{k+1,n-1}(c\alpha_{j_1}) F^{\gamma}_{k+1,n-1}(c\alpha_{j_2})
recalling two convergence results that we need in our proofs.\
From [@cri-pra Proposition 3.1], we can get the following result.

\[thm:triangular\] Let $({\mathbf T}_{k,n})_{ 1\leq k\leq k_n,\, n\geq 1}$ be a triangular array of $d$-dimensional real random vectors, such that, for each fixed $n$, the finite sequence $({\mathbf
T}_{k,n})_{1\leq k\leq k_n}$ is a martingale difference array with respect to a given filtration $({\mathcal G}_{k,n})_{k\geq 0}$. Moreover, let $(t_n)_n$ be a sequence of real numbers and assume that the following conditions hold:

-   ${\mathcal G}_{k,n}{\underline{\subset}} {\mathcal G}_{k, n+1}$ for each $n$ and $1\leq k\leq k_n$;

-   $\sum_{k=1}^{k_n} (t_n{\mathbf
      T}_{k,n})(t_n{\mathbf T}_{k,n})^{\top}=t_n^2\sum_{k=1}^{k_n} {\mathbf
      T}_{k,n}{\mathbf T}_{k,n}^{\top} \stackrel{P}\longrightarrow \Sigma$, where $\Sigma$ is a random positive semidefinite matrix;

-   $\sup_{1\leq k\leq k_n} |t_n{\mathbf T}_{k,n}|


crush on the local lifeguard? Fake your own drowning so you can get the chance to kiss her. How to make friends in a new neighborhood when school is out? Join the local group of rambunctious boys on their cherished baseball field, and let them teach you the game. And when you have a huge problem like knocking your stepdad’s baseball autographed by Babe Ruth into the yard with a vicious dog in it…well, it will feel like the end of the world, but at least your friends will help you! And maybe years later you’ll be laughing about it.

Now and Then (1995)

There are very few great coming-of-age films for girls and women. Among that small group, Now and Then might just be the definitive one. It’s specialany time.

Judd Nelson’s John Bender is another one of those special teenage characters. It’s hard not to watch the film without thinking that in his own way, John Bender was the epitome of cool.

The Outsiders (1983)
If the kids of Shermer High in The Breakfast Club thought they had it bad—if Allison the “basket case” thought she was ignored by her parents—then they should have paid a visit to the Greasers. The Greasers (very young stars of the time like Rob Lowe, Matt Dillon, Ralph Macchio, and Tom Cruise) were boys who weren’t just ignored: they were either beaten, orphaned, or non-existent. The Outsiders is a coming of age tale about one of the Greasers and his friends; all young men who were left to fend for themselves to


where they should be,
they could be anywhere!

I went to the bathroom and glanced at the sink,
the toilet tank cover didn’t hold them at all,
I gazed at the tub, but I don’t wear them to bathe,
I viewed where the ointments sit in a row,
I ogled the t.p., stored in its stack,
the rolls stayed silent, the glasses weren’t there.
I went to the car and checked over the visor,
I scoured the floor, even under the seats,
I got out a ladder and went up to the roof,
the gutters were filled with debris, not eyewear,
the whole roof was bare of spectacles too.
I called nine-one-one and they laughed in my ear,
I tried four-one-one and they hadn’t a clue.
I asked my neighbors if they’d seen them around,
they seemed quite concerned, a bit alarmed,
but had notQ:

How to check if HTML5 session storage has enough space for storing new item

I want to store an array of items in html5 session storage.
But before storing new items in array I want to see if there is enough space and if it doesn't has enough I want remove first element and add new item.
How I can know about available space in session storage?

A:

Try to put the data there and catch possible error:
try {
    sessionStorage.setItem('key', data);
} catch (e) {
    if (e.name === 'QuotaExceededError') {
        /* do something else */
    }
}


or images in signatures your post count must be 10 or greater. You currently have 0 signatures.

The first question would be is your slug barrel rifled? If that is case then it has no choke and will not pattern buckshot. If it is a smooth bore it is an I/c choke and is going to pattern the same as any 18.5" I/c barrel you get.

Next is since money is an issue then the Remington factory barrel - 18.5 Parkerized Police barrel with bead sight and a fixed I/C choke is the best value out there at $101 on the Remington parts list or as little as $98 from Remington parts Dealers (like me)
Or, if he has to match the Express finish then the same barrel in the Expressthe BOD.sub.5. Subsequent treatment in a stage containing heterotrophic bacteria where no oxygen is added anaerobic conditions) (anaerobic sufficient organic carbon is present results in reduction of nitrate nitrogen to elemental nitrogen which is given off in gaseous form.
Organisms responsible for oxidation of carbonaceous organic material are ubiquitous and are generally considered to be largely heterotrophic organisms such as zooglea, pseudomonas and chromobacterium which require organic carbon as a food and energy source. Organisms responsible for nitrification are classed as chemotrophic because of their ability to fix inorganic carbon (CO.sub.2) as their carbon source. Nitrosomonas and nitrobacter are representative of the group responsible for nitrification. Denitrification is accomplished by facultative organisms capable of utilizing the oxygen in the nitrate form. Schematically the various transformations are represented as follows:
Heterotrophic


Organisms Organic C + O.sub.2 .fwdarw. CO.sub.2 + H.sub.2 O + Cells Nitrosomonas 2NH.sub.4 .sup.- + 3O.sub.2 .fwdarw. 2NO.sub.2 .sup.- + 2H.sub.2 O + 4H.sup.+ Nitrobacterium 2NO.sub.2 .sup.- + O.sub.2 .fwdarw. 2NO.sub.3.sup.- Facultative 2NO.sub.3 .sup.- + Organic C .fwdarw. N.sub.2 + 3CO.sub.2 Heterotrophic Organisms
In conventional biological nitrification and denitrification systems the growth rate of the organisms responsible for nitrification is much slower than the heterotropic organisms. Thus long cell residence times are required to maintain a viable nitrifying mass in order to prevent washing out of nitrifiers either in the effluent or in the wasted sludge. The nitrification rate is strongly dependent upon pH, the optimum value lying between 7.5 and 8.5. Oftentimes it is necessary to add alkalinity to sewages deficient in alkalinity in order to maintainthe parties an opportunity to
work through their marital difficulties. Mother initially refused the idea, but she finally
agreed in an attempt to save her marriage. According to Father, on November 24, 2015,
he and Mother signed a letter to the Bureau of Immigration in India in the presence of an
Executive Magistrate giving written permission to the paternal grandfather “to submit
forms, applications, and other necessary documents” so that the Child could receive
status as a registered Overseas Citizen of India (“OCI”).1

       Soon after departing India without the Child, Mother began to question the
decision. She sent multiple text messages and emails to Father expressing her concern
and also her displeasure with the fact that he did not exhibit a desire to save the marriage.
Over time, she concluded that


a conveyance to her of certain rights she alleges in
             and to [Father]’s parents’ house at Mohali, Punjab, India. . . .
             This matter is still pending in trial court in Mohali, India.

             f. On June 15, 2016, [Mother] filed a complaint under the
             Protection of Women from Domestic Violence Act of India
             wherein she requested “custody/temporary custody/interim
                    Chandigarh.

             g. . . . [Father] finally filed a petition for divorce under the
             Hindu Marriage Act in the District Court of Chandigarh,
             India, a court of competent jurisdiction, on July 30, 2016. . . .
             [Father]’s complaint for Divorce was accompanied by his
             Application for a restraining order seeking to enjoin [Mother]


 II. ISSUE

       We limited review to the following issue:

              Are the orders of the Indian court in the matters pending in
              India entitled to the full faith and credit, such that the trial
              court lacks jurisdiction over custody of the minor child, under
              the Uniform Child Custody Jurisdiction and Enforcement
              Act.

     CHICAGO (CBS) — A Jewish woman said she was asked to leave the Chicago Dyke March for displaying a rainbow flag with a Jewish Star of David on it.

Jewish people celebrating Saturday’s march in Chicago were reportedly told not to display Star of David flags, as others found them “offensive.”

The flag was banned from the Dyke March, which is an annual celebration in the city. Several people carrying a flag with a Jewish Star on it were removed from the march because, according to a member of the Dyke March collective, their presence “made people feel unsafe,” Windy City Times reports.

Sunday afternoon, the Chicago Dyke March released a statement on Twitter addressing why they asked some to leave. It said, in part:

“The Chicago Dyke March Collective is explicitly


The authors confirm that all data underlying the findings are fully available without restriction. All data underlying the findings in our study are freely available in the paper.

Introduction {#s1}
============

The role of olfactory cues in shaping mosquito behavior in response to host odor has been studied extensively [@pone.0103765-Geier1]--[@pone.0103765-Allan1]. In those studies, the use of olfactometers was established to monitor the orientation (attraction/repellency) of flying mosquitoes towards an odor source. In other studies, a mosquito landing approach was used in which the number of mosquitoes landing on a treated substrate (e.g. human skin) was used as indicator for attraction/repellency of the compound [@pone.0103765-Syed1]--[@pone.0103765-Dube1].

Here, we follow a terminology that was proposed to describe mosquito olfactory cues [@pone.0103765-Dethier1]; an "attractant" is a substance that encourages mosquitoes to make oriented flights towards theboth chambers (two fingers of an experimenter). Mosquitoes did not discriminate between the two sides (p = 0.792, Student *t*-test, n = 6) showing no side bias. We also tested whether mosquitoes could discriminate the side that contains an attractive odor (two fingers) when there is no odor in the other side (two fingers covered with a glove). Mosquitoes preferred the chamber with the attractant more than the chamber with no odor (p = 0.027, Student t-test, n = 3). This shows that mosquitoes could follow the odor plume of an attractant in the olfactometer.

Afterwards, all compounds were tested twice with two different skin odors (two experimenters). With skin odor 1 (experiment 1), each compound was tested using 5 groups of mosquitoes and each group was tested twice to confirm there was no side bias (once


*t*-test, n = 7, [Fig. 3B](#pone-0103765-g003){ref-type="fig"}).

Oviposition behavior {#s3b}
--------------------

We tested the oviposition effect of the four compounds at three different concentrations (1, 10, and 100 ppm). MDA was not deterrent at any concentration (p = 0.396, 0.472, and 0.484 for 1, 10, and 100 ppm, respectively, paired *t*-test, n = 5 each, [Fig. 4](#pone-0103765-g004){ref-type="fig"}, [Table 1](#pone-0103765-t001){ref-type="table"}). On the other hand, EA had no effect at 1 ppm but was deterrent at 10 and 100 ppm (p = 0.774, 0.017, and \<0.001, respectively, paired *t*-test, n = 5 each, [Fig. 4](#pone-0103765-g004){ref-type="fig"}, [Table 1](#pone-0103765-t001){ref-type="table"}). BA had no effect at 1 ppm (p = 0.513, paired *t*-test, n = 5, [Fig. 4](#pone-0103765-g004){ref-type="fig"}, [Table 1](#pone-0103765-t001){ref-type="table"}) but surprisingly showed a strong oviposition deterrence at 10 and 100 ppm (p\<0.001, paired *t*-test, n = 5, [Fig. 4](#pone-0103765-g004){ref-type="fig"}, [Table 1](#pone-0103765-t001){ref-type="table"}). DEET was not deterrent at 1 or 10 ppm and only deterrenteffect was not large, and may be irrelevant in a field situation.

MDA was repellent against host seeking mosquitoes but had no effect on gravid females, at least at the tested concentrations. One reason could be that the effect of MDA is specific for host seeking behavior. It has been shown that olfactory responsiveness of female mosquitoes towards host odor is reduced following blood feeding [@pone.0103765-Klowden1]--[@pone.0103765-Takken1]. This reduced response was attributed to down-regulation of odorant receptor expression after a blood meal [@pone.0103765-Fox1]. MDA could therefore be selectively repellent for host seeking behavior due to a sensitivity change through the gonotrophic cycle of the female mosquito. Another reason could be that unlike other repellents, MDA might not have a strong repellent smell *per se* but rather a smell that masks


in an arm-in cage host seeking paradigm [@pone.0103765-Kain1], we conclude that BA has a general repellent effect only in still air situations when mosquitoes are allowed to land on (or above) a treated surface, whether this surface is an oviposition substrate or human skin.

In conclusion, our results together with others suggest that the compound MDA is a host seeking repellent. EA on the other hand is a general repellent comparable to DEET, while BA inhibits oviposition and acts as a limited repellent in a host-seeking context. These substances could be integrated in mosquito control programs, either against host seeking (MDA) or egg laying behavior (BA) or both (EA). Future studies, in which field or semi-field experiments are used, need to confirm the potential of these compounds against mosquitoesthe Fascist Government by the addition of fasces.

Municipalities
Most populated municipalities
Below is a list of the ten municipalities of the province sorted by number of inhabitants at 31 December 2010:

See also
Aveto Natural Regional Park

References

External links

 Wikipedia in Ligurian language
Official website

Genoa
.01
Genoa
Category:2015 disestablishments in Italy
Category:States and territories disestablished in 2015


back to zero ITME ', the regression lines for pens in positive energy balance gave an estimate of .420 MJ loss, After 7 days on experiment, the energy retained as fat (RE'f) and as protein (RE'p) increased approximately linearly with ITME ', but after 14 days some curvature was apparent, the deposition of protein increasing more rapidly at the lower levels of energy input, and the deposition of fat increasing more rapidly at the higher levels of energy input. The RE'p was only slightly higher on the proteogenic diet than on the lipogenic diet, at the same level of ITME ', but the effect of basal diet on RE'f was considerable. For both diets at RE' = 0 there was gain in body protein accompanied by loss ofdemonstrated heterogeneity of response to cytotoxic drugs \[[@pone.0140721.ref004]\].

The PC-3 human prostate cancer cell line has been shown to be a promising model to study tumor heterogeneity. The differential morphology of parent PC-3-GFP, PC-3-GFP-circulating tumor cells (CTC) and disseminated PC-3-GFP cells. Disseminated tumor cells (DTC) from multiple metastatic sites were compared. The cultured CTC and DTC from various organs had distinctive morphologies. The distinct morphologies were maintained during in vitro culture \[[@pone.0140721.ref005]\].

In the present report, we describe isolation of high metastatic variants of PC-3-GFP human prostate cancer cells by serial cycles of isolating lymph node metastasis in nude mouse models. There was a marked shift in the heterogeneous population of cancer cells within this high metastatic variants compared to parental cells that caused drug sensitivity as well as very


node, axillary node, and cervical node (A&B). The morphology of in vitro cultured metastatic PC-3-GFP-LN cells, from each cycle, cultured from inguinal lymph node metastasis and parental PC-3-GFP are shown. The giant cell number was enriched with the cycle number, indicating that giant cells are more aggressive and highly metastatic cells.](pone.0140721.g001){#pone.0140721.g001}

The PC-3-GFP-LN-6 variant contained round, spindle and giant cells ([Fig 2](#pone.0140721.g002){ref-type="fig"}). The giant cells contain multiple-nuclei. The number of nuclei per cell ranges between 2--22 ([Fig 2](#pone.0140721.g002){ref-type="fig"}). The giant cells may contain more information and higher ability of metastasis than single-nuclei cells. Giant cell number increased with each selection, which in turn became more metastatic, presumably due to the increased number of giant cells.

![Cellular morphology of PC-3-GFP-LN-6 (A-C).\
PC-3-GFP-LN-6 contained round, spindle and giant cells. The giant cells containAn automatic sewing machine system which processes pallets containing workpieces is illustrated in U.S. Pat. No. 4,422,393 entitled "Sewing Machine Having Automatic Pallet Handling". This system processes pallets from an input location to a sewing location and thereafter to a remote location wherein a further pallet may be automatically processed from the input location to the sewing location. The processing of pallets to the sewing location is accomplished by a set of rotatable shelves that cooperate in a manner which allows first one edge of a pallet to be dropped before a second edge is dropped to the sewing location. The thus dropped pallet is locked to a carriage which is movable in the X and Y directions relative to a reciprocating sewing needle so as to thereby


files).  It takes about half an hour to set up this project (so I carefully rebuild the indexes once per night, and use the files for the day, accepting that they are a little less accurate at the end of the day).  It allows me to track down unused stuff, and find out where stuff is used, and so on.
If you're used to an IDE, it will be primitive.  If you're used to curses-mode programs (vim, etc), then it is tolerably friendly.

that can speak about both not only of cytogenetic instability, but and the degree of environmental genotoxicity, in particular, ambient air. There was noted the tendency to increase the level of cytogenetic damage and destruction of the nucleus in the group of girls in comparison with boys.


students with three faculties: Arts, Science and Commerce. The college is affiliated to Gauhati University which is an institute of higher repute in the country. Having contributed significantly to the academic and cultural life of Dhekiajuli, in the college has not only withstood the test of time but has also carved a niche for itself in the sphere of higher education in Assam.

Originally, the college offered education in higher secondary and degree only in Arts. However, in the latter part of the eighties, the need for the Science was strongly felt and in 1992 the college introduced the Science faculty with well-equipped laboratory facilities. To meet the growing demand opened by the corporate enterprises, the college started the B.Com Three Years Degree Course in the session 2010-11. Theis connected to the user's television in a similar fashion to a conventional cable-TV decoder.
Along with the audio and video signals associated with the television channels, the satellite transmits various files such as text and graphics. These files and portions of these files may be used by the IRD to provide the user with additional information such as supplements to an electronic program guide. For example, a file may describe a particular actor or identify a movie's director.
Typically, these files are stored in a relational database and retrieved by key fields. However, relational databases, particularly in an IRD environment, are slow and consume a large portion of RAM. Consequently, users must wait to retrieve program guide data and/or the cost of the IRD is increased by additional memory.


1:26–27; Jas 3:9). In the economy of grace, God’s saving wisdom and power are revealed in the weakness and folly of the cross, choosing the lowly and despised things of the world (1 Cor 1:17–31). As the New Testament scholar John Barclay concludes in his 2015 book Paul and the Gift, “the Christ-event fits no preformed evaluative schema.... Baptism ‘into Christ’ provides a radically new foundation for communities freed from hierarchical systems of distinction, not because of some generalized commitment to ‘equality’ but because of the unconditioned gift of Christ, which undercuts all other reckoning of worth.”

That is, God’s raising a crucified Jew from Nazareth as Messiah and Lord recalibrates human worth, requiring us to have new eyes for our neighbors and especially for the most vulnerable inour midst.

Detractors from Celsus to Nietzsche gaze upon the body of Jesus nailed to the cross and perceive only weakness, folly and the scandal of something useless in a world of power—something that must be eliminated. But those who believe the good news that “he has risen; he is not here” behold on the cross nothing less than the image of the invisible God and prepare for the beatific vision by conforming to “the image of the Son” in cruciform love for others (Rom 8:28).

A world indifferent or hostile toward the claims of faith needs reminding that every last one of us is dust, and to dust each of us, in our utility and inevitable burdensomeness, shall return. Those who cleave for life to a crucified and risen


that occurred on February 19th, 2019 on the Sproul Plaza (UCPD case #19-00455). Based on current information available to the department, the suspect is not a student at, or affiliate of the University. This is still an active investigation and to support its efforts to apprehend the suspect, UCPD is encouraging anyone with information regarding this case to contact the UCPD Criminal Investigations Unit at: (510) 642-0472 during business hours, except holidays; and (510) 642-6760 at all other times. The University has also confirmed that the victim is not a student at, or affiliate of the University, and had joined members of a student group as a member of an advocacy training program. “The fact that the victim was not a campus affiliate has no bearing on thisconnected through a variety of networks 5. This requires a system of replication, where the database is replicated in multiple locations. In such a system, data synchronization management between the databases becomes critical to ensure reliable data at every location.
One such system, “Smallworld 3” from GE Smallworld, Inc., manages the replication and synchronization of version managed databases by relying on a single process to connect live to all of the databases at once in order to synchronize. This single process gains exclusive control of the relevant versions and records in all of the databases being synchronized, thus preventing access to the data during the synchronization process. In the case where the network 5 connecting the version managed databases 1 is unreliable or high-speed communications between database 1 sites


becomes the Yukawa potential $V_Y(r) \propto \frac{e^{-mr}}{r}$ in the ideal superconductor obeying the London equation. Similarly, the dual gluon $B_\mu$ is expected to be massive in the the monopole-condensed system, and the mass acquirement of $B_\mu$ leads to the dual Meissner effect. In other words, the acquirement of dual gluon mass $m_B$ reflects monopole condensation, and brings electric confinement. Hence, we can investigate the dual Higgs mechanism in QCD by evaluating the dual gluon mass $m_B$, which is evaluated from the inter-monopole potential.

To estimate the inter-monopole potential, we propose the dual Wilson loop $W_D$ [@INNOCOM_Tanaka; @YKIS_Suganuma]. The dual Wilson loop $W_D$ is defined by the line-integral of the dual gluon field $B_\mu$ along a closed loop $C$, $$W_D(C) \equiv
Re[\exp{(i \oint_C B_\mu dx_\mu)}],
\label{eq:def-dw}$$ which is the [*dual version ofthe study of the dual Higgs mechanism in QCD, we numerically calculate the dual gluon propagator $G^D_{\mu\mu}(r_{\!\!_E}) \equiv \langle B_\mu(x) B_\mu(x) \rangle_{\rm MA}$ and try to estimate of the effective mass $m_B$ of the dual gluon field $B_\mu$ in the MA gauge using the SU(2) lattice with $24^4$ and $\beta=2.4,2.45$. All measurements are performed at every 200 sweeps after a thermalization of 10000 sweeps using the heat-bath algorithm. We prepare 60 samples of gauge configurations. These simulations have been performed using NEC SX-4 at Computation Center of Osaka University.

For the effective-mass acquirement of the dual gluon $B_\mu$ as the result of infrared monopole condensation, we evaluate the dual gluon propagator obtained from the lattice QCD in the MA gauge. Since the massive vector-boson propagator is expected to behave


$B_\mu$ supports the dual Higgs mechanism by monopole condensation in the QCD vacuum.

Summary and Concluding Remarks
==============================

In order to clarify the dual superconductor picture for the quark confinement mechanism in the QCD vacuum, we have studied the effective-mass acquirement of the dual gluon field, which is essential for the dual Higgs mechanism. In the maximally abelian (MA) gauge, QCD is reduced into an abelian gauge theory including both the color-electric current and the color-magnetic monopole current.

For the investigation of the dual Higgs mechanism by monopole condensation in QCD, we have introduced the dual gluon field $B_\mu$ and have studied its features in the monopole part (the monopole-current system) using the MA gauge in the lattice QCD Monte Carlo simulation. Owing to the absence of the electric current, the monopoleobeys the perimeter law for large loops. Considering the finite-size effect of the dual Wilson loop, we have numerically derived the inter-monopole potential $V_M(r)$, and have found that $V_M(r)$ is short-ranged and flat in comparison with the linear inter-quark potential. Then, we have compared the inter-monopole potential $V_M(r)$ with the Yukawa potential and have estimated the dual gluon mass as $m_B \simeq {\rm 0.5GeV}$, which is consistent with the phenomenological parameter fitting in the dual Ginzburg-Landau theory [@SST]. The generation of the dual gluon mass $m_B$ supports the realization of the dual Higgs mechanism and monopole condensation in the QCD vacuum. To explain the short-range deviation between the inter-monopole potential $V_M(r)$ and the Yukawa potential, we have considered the effective size $R_{^{_{\rm M}}}$ of the monopole, which is


“Quarks, Leptons and Gauge Fields”, (World Scientific, Singapore, 1991) 1.

I. J. R. Aitchison and A. J. G. Hey, “Gauge Theories in Particle Physics” (Adam Hilger, Bristol and Philadelphia, 1992) 1.

W. Greiner and A. Schafer, “Quantum Chromodynamics” (Springer,1994) 1.

H. J. Rothe, “Lattice Gauge Theories” (World Scientific, 1992) 1.

Y. Nambu, .

G. ’t Hooft, .

S. Mandelstam, .

A. A. Abrikosov, “Fundamentals of the Theory of Metals” (Adam Hilger, 1988) 1.

R. W. Haymaker, V. Singh, Y.-C. Peng and J. Wosiek, . V. Singh, D. A. Browne and R. W. Haymaker, .

H. Suganuma, S. Sasaki, and H. Toki, .\
H. Ichie, H. Suganuma and H. Toki, Phys. Rev. [**D 52**]{}, 2994 (1995); [**D 54**]{}, 3382 (1998).\
S. Umisedo, H. Suganuma and H. Toki, Phys. Rev.[**D 57**]{}, 1605 (1998).

G. ’t Hooft, .

Z. F. Ezawa and A. Iwazaki, [Phys. Rev.]{} [**D 25**]{}, 2681 [(1982)]{} ; [**D 26**]{}, [631]{} [(1982)]{}.

A. S. Kronfeld, G. Schierholzand U.-J. Wiese, .

F. Brandstater, U.-J. Wiese and G. Schierholz, .

T. Suzuki and I. Yotsuyanagi, . S. Hioki, S. Kitahara, S. Kiura, Y. Matsubara, O. Miyamura, S. Ohno, and T. Suzuki, .

O. Miyamura, Phys. Lett. [**B 353**]{}, 91 (1995); Nucl. Phys. [**B**]{} (Proc. Suppl.) [**42**]{}, 538 (1995).\
O. Miyamura and S. Origuchi, “Color Confinement and Hadrons (Confinement ’95)”, edited by H. Toki, Y. Mizuno, H Suganuma, T. Suzuki and O. Miyamura, (World Scientific, 1995) 65.

R. M. Woloshyn, .

T. DeGrand and D. Toussaint, Phys. Rev. [**D 22**]{}, 2478 (1980).

J. D. Stack, R. J. Wensley and S. D. Heiman, .

G. S. Bali, V. Bornyakov, M. Muller-Preussker and K. Schilling, Phys. Rev. [**D 54**]{} 2863 (1996).

A. Di Giacomo, Nucl. Phys. [**B**]{} (Proc. Suppl.) [**47**]{}, 136 (1996) and references therein. M. I. Polikarpov, Nucl. Phys. [**B**]{} (Proc. Suppl.) [**53**]{}, 134 (1997) and references therein.

H. Suganuma, A Tanaka, S Sasaki and O Miyamura, Nucl. Phys. [**B**]{} (Proc. Suppl.) [**47**]{}, 302 (1996).\
H. Suganuma, M. Fukushima, H. Ichie, and


variable frequency in .632+ bootstrapped runs of the 116 discriminatory gene set in all cohorts, meaning that they were most frequently present in the trees of the random forest analyses performed (Additional file [3](#S3){ref-type="supplementary-material"}: Table S3). Their possible role in TB, lung disease or inflammatory processes is displayed in Table [4](#T4){ref-type="table"}. While the minimal set was a mere combination of genes that had a good predictive value for active TB in each of the source databases, the robust ten gene set represents a set of genes that perform well in the discrimination of active TB from LTBI and HC in all datasets used for its composition and probably also as in future cohorts from other study sites. The overlap between the minimal nine gene set for TB vs.poorly understood phenomenon \[[@B36]\]. In lung tissue, several processes related to calcium homeostasis are thought to contribute to *M. tuberculosis* persistence and the aggregation of macrophages in granulomas. Over-production of 1,2-dihydroxyvitamin D3, which plays a traditional role in calcium metabolism, in alveolar macrophages in granulomas has a protective effect against oxidative injuries from the nitric oxide burst from granulomatous macrophages \[[@B37]-[@B39]\]. Furthermore, *M. tuberculosis* inhibits a calcium-dependent phagolysosome formation pathway which leads to the prevention of maturation of *M. tuberculosis*-containing phagosomes into phagolysosomes. This process, referred to as the *M. tuberculosis* phagosome maturation arrest, is critical for *M. tuberculosis* persistence in the human host \[[@B22]\]. S100P, which significantly discriminated TB from LTBI in our study children, and TAS2R46, which significantly distinguished TB cases from HC, are genes involved


a newly identified cohort from a different geographic region. As the datasets used for the composition of the minimal set were based on European, African and South American populations the minimal set may not be applicable to individuals from Asia, while this region carries almost two-third of the global TB burden \[[@B42]\]. Furthermore, this signature set could be only indicative of damage to the lung epithelium, similar to what has been described for the overlap of the gene set determined by Berry *et al.*\[[@B4]\] and the biosignature characteristic for sarcoidosis \[[@B7]\]. Therefore, we used bootstrapping procedures to select a robust set of ten genes that had a high discriminative value in our population, in the two populations described by Maertzdorf *et al.*\[[@B5],[@B6]\] and in the comparison between TB,patient recruitment and sampling; PH: supervision and funding of microarray, qRT-PCR and bioinformatic analyses; LV, AZ and PH wrote the paper. All authors commented on the manuscript. All authors read and approved the final manuscript.

Supplementary Material
======================

###### Additional file 1: Table S1

Detailed characteristics of 27 children with TB, LTBI and HC in which microarray analyses were performed.

######

Click here for file

###### Additional file 2: Table S2

Enriched gene sets in the 116 gene set.

######

Click here for file

###### Additional file 3: Table S3

Sheet 1. Minimal discriminatory gene set to discriminate between TB and LTBI. Sheet 2. Minimal discriminatory gene set to discriminate between TB, LTBI and HC. Sheet 3. Variable frequencies estimated by the bootstrapping procedure implemented in VarSelRF (1). Sheet 4. Variable frequencies estimated by the bootstrapping procedure implemented


Use of carbon nanotubes and electrothermal atomic absorption spectrometry for the speciation of very low amounts of arsenic and antimony in waters.
A procedure for the determination of inorganic arsenic (III, V) and antimony (III, V) in water samples by using a miniaturized solid-phase extraction with carbon nanotubes followed by electrothermal atomic absorption measurement is proposed. The trivalent species are first complexed with ammonium pyrrolidinedithiocarbamate, next retained in a mini-column containing nanotubes and then eluted by means of a plug of an ammonia solution. The atomizer is impregnated with a tungsten salt which acts as an effective chemical modifier during the heating cycle. Total inorganic arsenic and antimony are determined after the reduction of the pentavalent forms with an ammonium iodide solution. Pentavalent arsenic and antimony are calculated byIn recent years, there has been an ever-increasing utilization of satellite television systems (TVRO) and cable TV which has created an increased demand by an ever-increasing audience for programming beyond the typical programming presently commercially available. This has led to the development of premium channels and other "special event" premium programming which is accessible only upon the payment of an additional fee, i.e. such as in pay-per-view (PPV) which permits a viewer of specific special event programming to pay a surcharge for the privilege of viewing the "special event" over his cable TV connection. Such "special events" have included major sporting events, first run movies, and other programming which is not ordinarily commercially available. This has met with wide success and has greatly enhanced the desirability of subscribing


it more convenient and safer. To transmit a drawing via iTunes, users just need to connect an IOS device to a PC with a USB cable, open iTunes and switch the page of the device, choose the application in the menu, find GstarCAD MC PRO in file sharing section and click “Add” button. Then, the drawings will be added into local drawing page system. Besides, according to this update, users can send the drawings to their E-mail boxes or network disks, then download the files to GstarCAD MC PRO to browse and edit. There’s no need to copy drawings to iPhone/iPads via USB cable. The transmission is becoming more convenient and easier. Users also can send the drawings which are edited and annotated by GstarCAD MC PRO as$\leqslant T \leqslant$ 230 K for 2ENO/1LNO SL (see Appendix: Fig. \[fig:Fig6\]). Such classical percolation picture has been reported in other oxides as well when they undergo normal to superconducting phase transition [@kiss1994noise; @daptary2016correlated]. It can be seen from Fig. \[fig:Fig3\] that the magnitude of noise of 1ENO/1LNO is three orders larger than that of 2ENO/1LNO. Large increase in noise have been seen in other oxide undergoing long range charge-ordering transition [@bid2003low]. We speculate that because of the absence of long range CO in 2ENO/1LNO SL, noise magnitude is smaller than 1ENO/1LNO SL.

While the origin of noise in metallic phase can be understood from the Dutta-Horn model  [@dutta1981low; @daptary2017effect], such defect scattering based mechanism fails to explain the peculiar behavior of noise in the temperature range $0.85 \lesssim T/T_{MIT} \lesssim


             input buffer to checksum
 * \param inLen              length of input buffer
 * \param crc32              pointer to Uint32 to store the final CRC into
 *
 * \returns 0 for OK, -1 on error
 *
 */
int SDLTest_Crc32Calc(SDLTest_Crc32Context * crcContext, CrcUint8 *inBuf, CrcUint32 inLen, CrcUint32 *crc32);

/* Same routine broken down into three steps */
int SDLTest_Crc32CalcStart(SDLTest_Crc32Context * crcContext, CrcUint32 *crc32);
int SDLTest_Crc32CalcEnd(SDLTest_Crc32Context * crcContext, CrcUint32 *crc32);
int SDLTest_Crc32CalcBuffer(SDLTest_Crc32Context * crcContext, CrcUint8 *inBuf, CrcUint32 inLen, CrcUint32 *crc32);

/**
 * \brief clean up CRC context
 *
 * \param crcContext        pointer toLexicon is a serif font originally created by Dutch designer Bram de Does, and most recently published by The Enschedé Font Foundry (TEFF). It’s a beautiful typeface, whether it deserves its huge $4,996 is a completely different question.

So is it worth it? Well it depends really, would I ever pay the best part of $5,000 for a typeface, no. However to companies that spend millions of dollars per year on marketing, spending five grand on a typeface that’s going to fit their branding perfectly really isn’t that much of a big deal.

Most typefaces nowadays price their fonts cheaply to make their product more accessible to the masses, and in turn hopefully get more sales. Lexicon however takes the complete opposite approach – they price their product at a


$U(1)$ gauge symmetries in $E_{8}\times E_{8}$. These symmetries can be broken by vacuum expectation values of singlet fields charged under the additional $U(1)$s. This then allows a mass term for the vector-like pairs and removes them from the low-energy spectrum. We have now to find a mechanism that removes all the vector-like exotics (including additional pairs of Higgs-doublets) and keep exactly one of the Higgs-doublet-pairs light. In the framework of supersymmetric models this is known as the $\mu$-problem. Within the MiniLandscape we can identify models that show a solution of the $\mu$-problem. In explicit constructions we remove vector-like exotics through couplings to singlet fields. This requires a determination of allowed terms in the superpotential $${\phi_1}^{n_1}....... {\phi_k}^{n_k}   H \bar{H}$$ at various orders in the power of singletfields $\phi_i$. Typically most vector-like pairs gain a mass at the first few orders (some-times all the Higgs-pairs are gone). But there are models where a Higgs-pair remains light even at higher orders in the singlet fields[^2]. It seems that the $\mu$-parameter of this particular Higgs-pair is protected by some new mechanism. A detailed inspection of these models reveals two important facts[@L]:

-   the Higgs-pair is living in the bulk,

-   its $\mu$-parameter is protected by a discrete $R$-symmetry.

This is a remarkable observation. The explicit string construction has provided a solution to the $\mu$-problem following from geometric and geographical properties of the compact manifold[@N]: the Higgs-pair lives in the bulk! But what is the origin of these discrete $R$-symmetries?

$R$-symmetries
==============

$R$-symmetries are defined as those symmetries that transform


compactified space. In addition the “geography” of fields in extra dimensions gives rise to many possibilities for discrete groups (through the influence of the string theory selection rules). In many cases the discrete symmetries lead to “better behaved” quantum field theories in the ultraviolet. They might be used to forbid certain counter terms and explain the appearance of large mass hierarchies.

Flavour symmetries
------------------

An obvious application concerns the flavour symmetries of quarks and leptons and the pattern of Yukawa couplings. In our simple example we had a non-abelian $D_{4}$ flavour symmetry (as a subgroup of flavour $SU(2)$) where the first two generations of quarks transform as a doublet. More general symmetries within the orbifold compactification of the heterotic string and other string constructions can be found in refs.[@I; @ACK; @ACK1;leads to a pattern of soft terms reminiscent of a mediation scheme[@Y1] known as mirage mediation[@Y2]. Bulk fields with $N=4$ will be subject to a no-scale structure [@YYY] of the soft terms: they vanish at tree level and will only become nonzero when coupling to other sectors with less supersymmety. Non-trivial $R$-symmetries can protect soft terms as e.g. gaugino masses. Fields localized at fixed points feel the full breakdown of superymmety, they are thus the heaviest of the supersymmetric partners. In the models at hand, these are the (localized) scalars of the first two generations of quarks and leptons. A hierarchical structure of soft terms emerges naturally[@S; @Z]. This implies that even in the framework of so-called low-scale SUSY only few fields might be found in the TeV-region,


1 hour, were obtained from wrist activity and light measurements. The trade-off between highest precision and least obtrusive configuration is discussed for applications to sleep and mood disorders caused by a misalignment of the internal phase with the external solar and social times.journalist Mike Elk discusses the election dispute in the CWA Newspaper Guild over the right to vote. According to Elk 2,000 members under the present bylaws are inelegible to vote in the upcoming election.

Bernie Lunzer who is president of the CWA Newspaper Guild is running unopposed in the upcoming election. According to labor journalist Mike Elk, delegates at a NG convention refused to change the rules to allow 2,000 members the right to vote in the election. Also the freelance members while paying dues are ineligible to vote under the present Newspaper Guild bylaws.

According to labor journalist Mike Elk, Dave Regan the president of SEIU UHW has been accused of sexual harassment and sexual misconduct and is now trying to get information from Google about who is whistleblowing


cognitive inhibition (prefrontal cortex) and the fear circuit of the amygdala-hippocampal-prefrontal axis are considered to be the neuroanatomical correlates for panic disorder. The neural perspective supports the idea that cognitive-behavioral therapy normalizes alterations in the top-down cognitive process among brain structures. An essential component of "personalized medicine" is the application of reliable indicators of predictions/outcomes, which are used to select the most appropriate therapeutic for subgroups of panic disorder. Consistent with the concept of "personalized medicine," the Research Domain Criteria can provide a more precise framework for further treatments that target the underlying dysfunctions of panic disorder and provide us with better definitions of moderators that can be used to identify subgroups, according to different responses to treatment.

Several cognitive, behavioral and neurobiological theories have been proposed to explainand anxiety. In addition, the insular integrates filtered sensory information via the thalamus from the sensory regions of the occipital, parietal, and temporal lobes and sends the information to the frontal regions for cognitive processing, and to the limbic system for primitive response, which causes the imbalance in panic disorder. Additional extensive and advanced neuroimaging studies that focus on imaging genetics, machine learning, and pattern recognition are necessary in the future, to confirm the role of the advanced fear network model in the pathophysiology of panic disorder.

Panic disorder is a complex heterogeneous multifactorial and polygenic disorder \[[@b7-pi-2019-01-08]\]. This heterogeneity not only complicates panic disorder diagnosis but also the treatment outcomes and prognosis. To date, no valid, specific, or sensitive biomarkers have been identified for panic disorder, or for


valid approach to include the susceptibility, diagnostic, prognostic, and predictive markers of panic disorder. Biomarkers would be more specific if they could be related to specific stages of panic disorder. In this review, the authors \[[@b8-pi-2019-01-08]\] shed light on the staging model of panic disorder with stagespecific biological markers.

In general, panic disorder can be effectively treated with pharmacological and psychological treatments such as cognitive behavioral therapy and mindfulness interventions \[[@b9-pi-2019-01-08]\]. Although pharmacological treatments have proven to be potent in panic disorder therapy, their potential side effects can be obstacles for adherence to treatment and the long-term maintenance of achieved treatment outcomes. Thus, it is important to provide effective psychological interventions for panic disorder either as adjunctive or stand-alone treatment. However, despite evidence-based psychological therapy programs, the availability ofthe examiner, not the patient, moving the target would be to retain some standardisation of the speed of movement.

Some early investigators[@bib0660], [@bib0680], [@bib0685] found lower results for AoA with the push-down method than with the push-up method. Later researchers[@bib0540], [@bib0545] found similar results with the two methods and speculated that the earlier findings were due to the difference in reaction time between the push-up and push-down methods. Another study[@bib0655] found similar results with the two methods, for 25 participants aged 10--40 years, citing other studies that found the same effect, but their push-down method used the end-point criterion of just recognising the test-object, giving large error due to depth of focus as shown by earlier research.[@bib0690] The error due to depth of focus in push-down to recognition would


have tended to counterbalance the error due to reaction time in push-up.

Some research[@bib0510], [@bib0695], [@bib0700] adopted the strategy of moving the push-up test object in step changes. This would have eliminated reaction-time error because the target was stationary during measurement. However, the increased testing time of this strategy may have reduced its utility and its accuracy.

Displacement {#sec0050}
============

This error is caused by displacement of the moving visual object beyond the end-point, as follows. The end-point is registered when, in the push-down method, the observer detects that the test object\'s sharpness stops changing. This judgement requires comparison of sharpness at points after passing the near point, whereas in push-up the observer seeks for the sharpness to start changing, by comparing the sharpness at points before and after passing the end-point.is horizontal.15.The other source of error inherent in the design of this instrument applies to monocular measurements. The error is that the rule is placed on the midline between the two eyes, rather than on the visual axis of the eye being measured.[@bib0680] This would inflate results by an amount that can be trigonometrically estimated as about 5% at the highest levels of AoA and approximately proportionately less at lower levels, so it is not as large as some other errors listed above. Correction for this source of error has been precise,[@bib0680], [@bib0815] approximate[@bib0535] or missing[@bib0665], [@bib0845] with the latter studies reporting higher upper measurements of AoA than other studies.

In the above list of sources of error arising from apparent weaknesses in the design and production of the


RAF Rule, published information was not found for items 1--13.

Measurement with the minus-lens method minifies the target because it is viewed through negatively-powered lenses. The negative power, and hence the minification, is greater at higher levels of measurement. The minification has been cited[@bib0525], [@bib0660] as a possible source of error. No theoretical or empirical reports were found of the size of this error being clinically significant.

When viewing through spectacle lenses, AoA may be influenced by refractive error, the degree of influence depending on the power of the lens.[@bib0635] This may be an additional source of error with the minus-lens method.[@bib0785]

Examiner bias {#sec0090}
=============

This is a source of error in any measurement that is not fully automatic. The practitioner examining the patient will often, and perhaps always, have an expectationrule\'s accuracy by measuring the near-point distance with a separate rule;-the practitioner should consider taking a first measurement using the push-up method and then moving the slider away from the patient to obtain a push-down measurement. The recorded AoA would be the average of these two values.[@bib0525], [@bib0530]

When using the minus-lens method, the visual object should be as close to the eye being measured as feasible, and minus-lens power should be changed slowly. For retinoscopy, the practitioner may consider reducing error by using a normal working distance such as 67 cm, adding minus lenses in the trial frame for the refracted eye. This possible method does not appear to have received research attention.

Notwithstanding these possible improvements to existing methods, a new AoA-measurement method has been sought by the current


service could be found for entity " + entityId);
        }

        val peerEntityContext = outboundContext.getSubcontext(SAMLPeerEntityContext.class, true);
        if (peerEntityContext == null) {
            throw new SamlException("SAMLPeerEntityContext could not be defined for entity " + entityId);
        }
        peerEntityContext.setEntityId(entityId);

        val endpointContext = peerEntityContext.getSubcontext(SAMLEndpointContext.class, true);
        if (endpointContext == null) {
            throw new SamlException("SAMLEndpointContext could not be defined for entity " + entityId);
                } else {
                    if (acsEndpointFromMetadata == null
                        || !adaptor.getAssertionConsumerServiceLocations(binding).contains(acsEndpointFromReq.getLocation())) {
                        throw new SamlException(String.format("Assertion consumer service from unsigned request [%s], does not match ACS from SP metadata [%s]",


        LOGGER.debug("Resolved AssertionConsumerService from the request is [{}]", acs);
            if (StringUtils.isBlank(acs.getBinding())) {
                throw new SamlException("AssertionConsumerService has no protocol binding defined");
            }
            if (StringUtils.isBlank(acs.getLocation()) && StringUtils.isBlank(acs.getResponseLocation())) {
                throw new SamlException("AssertionConsumerServicAcceptableUsagePolicySubmitActione has no location or response location defined");
            }
          *p* \< 0.001). More specifically, there was a strong decrease in the use of an overdose medication from 83.0% (95% CI 80.6%-85.2%) in 1987--1989 to 77.4% (95% CI 74.3%-80.2%) in the period 2011--2013 (χ^2^ for trend: 26.32 *p* \< 0.001) and a decrease in the use of pesticides or gases and unspecified chemicals and noxious substances from 5.5% (95% CI 4.3%-7.0%) in 1987--1989 to 2.8% (95% CI 1.9%-4.2%) in the period 2011--2013 (χ^2^ for trend: 38.25, *p* \< 0.001). During the 26 years of monitoring, females (85.7%; 95% CI 84.7%-86.6%) used significantly more commonly self-poisoning with an overdose of medication as method than males (74.6%; 95% CI 73.2%-75.9%; χ^2^ (1) = 169.98, *p* \< 0.001). Males (4.1%; 95% CI 3.5%-4.7%) used significantly more commonly self-poisoning with pesticides or


   1990--1992[\*](#t002fn001){ref-type="table-fn"}     411   74.6 (70.8, 78.1)   504   88.0 (85.0, 90.3)
                            1993--1995[\*](#t002fn001){ref-type="table-fn"}     406   79.1 (75.4, 82.4)   443   86.4 (83.1, 89.1)
                            1996--1998[\*](#t002fn001){ref-type="table-fn"}     496   76.0 (72.5, 79.1)   696   86.2 (83.7, 88.5)
                           1990--1992[\*](#t002fn001){ref-type="table-fn"}     19    3.4 (2.2, 5.3)      3     0.5 (0.2, 1.5)
                            1993--1995                                          43    8.4 (6.3, 11.1)     37    7.2 (5.3, 9.8)


                        1996--1998[\*\*](#t002fn002){ref-type="table-fn"}   27    4.1 (2.9, 6.0)      12    1.5 (0.9, 2.6)
                            1999--2001                                          10    3.6 (2.0, 6.5)      9coincides with a change in the definition of self-harm in the hospitals since 1994 as described in the method section. However, as the decline in rates of self-poisoning was much more outspoken than the change in rates of self-injury it is unlikely that the decrease in rates is attributable to the change of definition. It is possible that local prevention activities have contributed to the decrease in self-harm rates. For example, in 1995, we demonstrated a near-significant effect of home visits by a community nurse in case of non-compliance with referral to outpatient aftercare among self-harm patients after discharge from the A&E departments involved in the current study, on repetition of self-harm \[[@pone.0156711.ref034]\]. Since 1997, this activity has been integrated in a suicide prevention programme in which community


members.

As noted above, in Ethiopia, the quantitative data were supplemented by qualitative data. Specifically, in-depth interviews (IDIs) were conducted with ever-married women aged 18--45, who were married before the age of 18 years, and had been married for at least five years. In addition, participatory focus group discussions (PFGDs) were held with mothers and fathers who had daughters between the ages of 8 and 17 years in an urban and a rural site in Oromia and Amhara regions. Study participants were purposively selected based on demographic, socio-economic and cultural characteristics of the population. A total of 32 IDIs (16 in each region) and 8 PFGDs (2 with fathers and 2 with mothers in each region) were completed. Of the 32 IDIs completed, half were with women aged 18--24 years and theoutcomes. Also, given the cross-sectional nature of the survey, it is hard to fully account for endogeneity bias. However, given the normative preference for early marriage in both countries, the likelihood for psychological well-being to be a cause of early marriage seems very low. Moreover, the regressions controlled for many factors associated with child marriage and/or psychological well-being, including several community level variables. The cross-sectional nature of the data also limited our ability to examine the mechanisms by which child marriage impacts psychological well-being. Therefore, we were not able to parse out the direct and indirect effect of child marriage on psychological well-being, and hence the parameter estimates are likely to be an underestimation of the relationship between child marriage and psychological well-being. We tried to address this


losing control over the way you act, talk, think, feel or your memory during the past month?11I was emotionally stable and sure of myself this past monthVitality (VIT)12How much energy, pep, or vitality did you have or feel during the past month?13I woke up feeling fresh and rested this past month?14.Did you feel active, vigorous, or dull, sluggish during the past month?15.I felt tired, worn out, used up, or exhausted during the past monthPositive Well-being (PWB)16.How have you been feeling in general this past month?17.How happy, satisfied or pleased have you been with your personal life during the past month?18.My daily life was full of things that were interesting to me during the past month.19.I felt cheerful, lighthearted during the past month.General Health (GH)20.How often were you botheredBen Platt, who more than three years ago spoke the words and sang the music of “Dear Evan Hansen” for the first time, going on to win the Tony Award in June for best actor in a musical, will leave the celebrated musical in the fall, the show’s producers announced Monday.

His last performance at Broadway’s Music Box Theatre, where the show collected a total of six Tonys, will be on Sunday, Nov. 19, according to the production and Platt, who confirmed his departure on Twitter. “2 readings, 2 workshops, 3 productions and almost 4 years — hard to fathom that’s it’s nearly time to say goodbye to Evan and my DEH family,” Platt said.

In a portrayal that will be long remembered as an extraordinary Broadway milestone, Platt has


in the division of the separating art that follows. As the two groups of examples show, separation can be undertaken in two different ways: you can either separate like (homoios) from like, which is what i.e. spinning does, or you can separate worse (cheiros) from better (beltios), which is what i.e. straining does. This last kind of separation, which is identified as a kind of purification (katharmos tis), is what the ES is after. The other kind, the one that separates like from like, is, I believe, the one that has been practiced so far10. Kristian Larsen – The Soul of Sophistry Filosofiske Studier, årgang 2007, no. 102, side 4 af 14 ● www.filosofiskestudier.dk ● ISSN 0106-0449 If this is correct, the problem the foregoing descriptions have beenliving (empsychon) or Kristian Larsen – The Soul of Sophistry Filosofiske Studier, årgang 2007, no. 102, side 5 af 14 ● www.filosofiskestudier.dk ● ISSN 0106-0449 dead (apsychon); it makes little difference to it (i.e. the method) which name would seem most fitting. It only has to separate (chōris) the cleansing of the soul in binding all the other kinds of cleansing together. It was the cleansing of thought (dianoia) that now had to be separated from all others, that is, if we understand what it (i.e. the method) wanted." We see, then, that the function of this passage is to point out the difference between bodily and psychic purification, which is exactly the opposite of showing that every part of reality is as good as any other; first


the other is only willing to follow, and so it has always been"27. The implication is that virtuous conduct is basically a question of imitating good people's behaviour and of submitting oneself to the ruling norm. This can be seen as one of the main reasons why so many Greeks resented the sophistic movement: the sophists saw themselves as the educators of Greece, and they believed they had the 'technical' knowledge that according to them was required in order to make people virtuous. Their educational 'program' was thus a frontal attack on the "kalakagathos"-view, which in essence held that virtue is either something you are born with or something you simply 'learn' through imitation. The Socratic view of virtue can be said to follow the gist of theof fact, this methodological reflection can be said to be the Socratic conception of philosophy, in so far as its purpose was to show that the difference between philosophy and sophistry must be sought in the effect the two have on the soul. It is only with this criterion in mind that the real difference between the two can be shown. I believe that this new 'level' of inquiry is the basis for the rest of the dialogue. Philosophy is a certain kind of education and education is necessarily carried out through speech (logos, cf. 229d10). Philosophy is thus a certain kind of imitation of reality. The problem is that the sophist is Kristian Larsen – The Soul of Sophistry Filosofiske Studier, årgang 2007, no. 102, side 12


the unfortunate consequence that the passage doesn't have a real function for the development of the dialogue as a whole. W. K. C. Guthrie, A History of Greek Philosophy, vol. 5, Cambridge University Press, 2001. pp. 128-29, is basically of the same opinion as Trevaskis. 9 Many commentators have noted that the last bipartition of the fifth description (the "babbler" who doesn't earn any money vs. the professional "controversialist") reminds us of Socrates, cf. Friedländer, Platon III, Walter de Gruyter, Berlin 1960, 235 and Guthrie, 127-28 10 Cf. S. Rosen, Plato's Sophist, Yale University Press, 1983, 119-20, and S. Benardete, The Being of the Beautiful, The University of Chicago Press, II, 92 for a similar view. 11 J. Stenzel, Studien zur Entwicklung der Platonischen Dialektik, Wissenschaftliche Buchgesellschaft Darmstadt,"lack of regulation" ( breathtaking since regulations CAUSED this), and the ever popular..what was it..predator lending?..anti-bank/greedy big guys spiraled.

All needing the right politicians to step in and "save" us from these monsters.

Unfortunately, skilled populist politicians will always win over by preying on fearful people clutching their wallets, afraid of and against what they can't understand, looking for a savior, being bombarded by "sky is falling" media and candidates whipping them into a frenzy. Fear is easier fed than rationality. Remember the laughter at Bush rationally saying, post 9/11, "don't panic, keep living and buying"? His was the rational approach, and it worked. But "a Great Depression is coming" works better in an election year if the circumstances are right and the media support you.

Every move by the Feds


1% agarose gel electrophoresis was used to analyze the PCR products. The results were representative of three individual experiments.

3.6. Western Blot Analysis
--------------------------

BV-2 cells seeded at 40 × 10^4^ cells/mL and cultured in 6-well plates were rinsed twice with ice cold PBS after EOP and LPS treatment. The total cell extract was obtained by adding 80 μL RIPA buffer (1*×* PBS, 1% NP-40, 0.5% sodium deoxycholate and 0.1% SDS, containing fresh protease inhibitor cocktail). In a related experiment, a nuclear extraction kit from Thermo Scientific (Rockford, IL, USA) was used to separate nuclear proteins. Electrophoresis and immunoblotting procedures were carried out as per our previous report \[[@B41-molecules-19-19361]\]. PVDF membranes were incubated overnight with anti-iNOS (1:1000), anti-(inhibitor of κB-α) IκB-α (1:1000), anti-p-IκB-α (1:1000), anti-total-ERK (1:1000), anti-phospho-ERK (1:1000), anti-total-p38 (1:1000), anti-phospho-p38(1:1000) anti-β-actin (1:2000), anti-p65 subunit of NF-κB (1:500), anti-nucleolin (1:1000) and anti-COX-2 (1:2000) antibodies, followed by a 1-h incubation with horseradish peroxidase-conjugated secondary antibody (1:2000). The LAS-3000 Luminescent Image system (Fuji, Tokyo, Japan) was used to visualize antibody-specific bands on the PVDF membrane. Results are representative of three individual experiments.

3.7. Immunocytochemistry
------------------------

BV-2 microglia cells, seeded at 5 × 10^4^ cells/well on sterile cover slips, were cultured in 24-well plates. The cells were pre-treated with 10 µM EOP for 1 h followed by exposure to LPS (100 ng/mL) for 30 min. Cell fixation on cover slips and further steps were carried out as per our earlier report \[[@B41-molecules-19-19361]\]. Detection of the intracellularly localized p65 sub-unit of NF-κB was performed using a fluorescence microscope.

3.8. Statistical Analyses
-------------------------

GraphPad software ver. 5 (Graph Pad


Consequently, our study finds that serological examination is a method of tumor diagnosis through the examination of biomarkers in the serum. Clinically, after testing cytokeratin fragment 19 antigen 21-1 (Cyfra 21-1), neuron-specific enolase (NSE), alpha fetoprotein (AFP), carcino-embryonic antigen (CEA), carbohydrate antigen 125 (CA125), CA153, CA199, CA724, alkaline phosphatase (ALP), hemoglobin (Hb), and calcium in the serum during the serological examination to find different values of serum markers between IOM and NIOM. According to some recent research and clinical usage, CA153 was highly expressed in a variety of epithelial adenocarcinoma cells and exhibited a high positive rate in serous and mucous ovarian cancer. AFP is the most sensitive and specific marker for the early diagnosis of primary liver cancer ([@bibr19-1557988320908998]). CA125 is a glycosylated antigen that can beA common intron 3 mutation (IVS3 -48c-->g) leads to misdiagnosis of the c.845G-->A (C282Y) HFE gene mutation.
Amplification of the region of the HFE gene that contains the c.845G-->A (C282Y) mutation is usually performed using one amplimer that binds to a sequence in intron 3 and another that binds to a sequence in intron 4. Previously, a mutation that interferes with efficient binding to the intron 4 site has been described. We now find that another common mutation in intron 3, IVS3 -48c-->g, prevents binding of the amplimer to that site. This polymorphism occurs at a gene frequency of 0.128 in the African-American population and at a frequency of only 0.006 in the European population. DNA samples heterozygous for the IVS3 -48c-->g polymorphism and C282Y were undistinguishable from samples


Yeezy asked the Keeping Up With The Kardashians star to marry him on her 33rd birthday last Monday (October 21), presenting Kim with a 15-carat Lorraine Schwartz sparkler at the AT&T Park in San Francisco.

Despite previously revealing that pregnancy was harder than she had anticipated, Kimmy has now told Extra that she's keen to give daughter North a sibling, stating: "[Becoming a parent is] everything you could ever imagine and more.

"It's the best feeling [and] it's the most rewarding job. I recommend everyone go through the process."

Speaking of her engagement, Kim also revealed that she was "shaking" when West popped the question, stating: "I had absolutely no idea, I think nobody one did.

"Everyone thought they were coming to San Francisco for my surprise day… It was a magicala well defined oval or round shaped mass but MRI provides superior evaluation of the orbit ([@R5]). MRI shows T1W hypo-isointensity and T2W hyperintensity. Variable homogenous or inhomogeneous contrast enhancement is the rule ([@R6]). These lesions have a small arterial input with small venous outflow channels and very slow flow within. These typical radiological features are seen in the present case.

Multiple cavernous hemangiomas of the orbit are extremely rare ([@R7]). Conjunctival cavernous hemangioma is also a rarity. It arises often from the conjunctival vessels and rarely from the scleral, muscular or orbital vessels ([@R8]). We here present a case of multiple cavernous haemangioma of orbit, which was superomedial in location and associated with conjunctival hemangioma; a rare entity. There are very few case reports of multiple CH of


someone in Bonn or Magdeburg forgot to repeal any laws, ordinances or decrees of the "pre-reunification" period, or because they have not yet been replaced by new state laws. No, in Magdeburg this happened on purpose.
In 1996, the Landtag adopted a special law on legal restructuring.
What is going on in Magdeburg? Has the PDS pushed or duped its toleration partners to at least partially preserve the "unjust state" of the GDR?
Not at all. The SPD politician Schubert said that apart from the Green Arrow, there were other "quite sensible regulations in the GDR which were not simply thrown overboard". She referred to the protection of nature and the environment, to regulations on leaving religious communities, and in the law on foundations. The GDR had often formulated laws moreSaxony-Anhalt's Minister of Justice Karin Schubert (SPD), that all laws from GDR times have automatically lapsed with the reunification. On the contrary: a large part of the 3300 GDR laws that fell under the jurisdiction of the states after reunification will remain in force until the East German parliaments repeal them or replace them with new ones. In June 1996 Saxony-Anhalt was the first of the new Länder to adopt a law on legal consolidation. It adopted 46 legal regulations of the GDR as state law. Of these, 14 were not adopted until 1990 under the de Maizière government, but most of them date back to the 1950s and 1960s.
All laws not listed in the Rechtsbereinigungsgesetz have been out of force since the end of 1996. Since


Electrosonic spray ionization. A gentle technique for generating folded proteins and protein complexes in the gas phase and for studying ion-molecule reactions at atmospheric pressure.
Electrosonic spray ionization (ESSI), a variant on electrospray ionization (ESI), employs a traditional micro ESI source with supersonic nebulizing gas. The high linear velocity of the nebulizing gas provides efficient pneumatic spraying of the charged liquid sample. The variable electrostatic potential can be tuned to allow efficient and gentle ionization. This ionization method is successfully applied to aqueous solutions of various proteins at neutral pH, and its performance is compared to that of the nanospray and micro ESI techniques. Evidence for efficient desolvation during ESSI is provided by the fact that the peak widths for various multiply charged protein ions are an order ofESSI is comparable to or even smaller than that in the case of nanospray, emphasizing the gentle nature of the method. The unique features of ESSI are ascribed to very efficient spraying and the low internal energy supplied to the ions. Evidence is provided that the method is capable of generating fully desolvated protein ions at atmospheric pressure. This allows the technique to be used for the study of ion-molecule reactions at atmospheric pressure and examples of this are shown.


\leq t_i^{j-2} \leq \ldots \leq t_i^{1} \leq t_i^0$ and for $j < 0, t_i^j \leq t_i^{j+1} \leq t_i^{j+2} \leq \ldots \leq t_i^{-1} \leq t_i^0$.

Denote by $\mc{T}_\ell^k$ the set of admissible sequences of $(k-1)$ paths in an $\ell \times \ell$ square.

\[pathseqex\] Fig. \[pathseq\]a is an element of $\mc{T}_4^3$, where $p_1$ and $p_2$ are shown in Fig. \[pathseq\]b and Fig. \[pathseq\]c, respectively. Notice that between $p_1$ and $p_2$, there is one box of color 0.

  ----------------- ----------------- -----------------
   ![image](Fig3a)   ![image](Fig3b)   ![image](Fig3c)
          a                 b               1 \leq i \leq k$, is an extended Young diagram and since we have exactly $\ell - |j|$ boxes available of each color, we obtain an extended Young diagram. Thus, we are able to draw a lattice path along the right edge of the new diagram. We take this path to be $p_{k-2}$. Now, we add the boxes of $Y_{k-1}$ in the same manner and draw $p_{k-3}$. We continue this process until we add in the final boxes of $Y_2$ to make a complete square. Let $\T$ be the sequence of $k-1$ lattice paths in the square. As before, we define $t_i^j$ to be the number of $j$-colored boxes between $p_{i-1}$ and $p_{i-2}$. Notice that $t_i^j$ is the number of boxes of color $j$ in $Y_i$. Since each


j_r \} \mapsto \{1, 2, \ldots, \ell \} \setminus \{w_{j_1}, w_{j_2}, \ldots, w_{j_r} \}$ in increasing order. It follows from the construction that $w$ is a 321-avoiding permutation.

Conversely, let $w = w_{1}w_{2}\ldots w_{\ell}$ be a 321-avoiding permutation of $[\ell]$. Define $C_{i} = \{j \mid j > i, w_{j} < w_{i} \}, c_{i} = |C_{i}|,$ and $J = \{ j_{1} < j_{2} <  \cdots <  j_{r} \} = \{j \mid c_{j} > 0 \}$. We define a path, $p \in T_{\ell}^2$, from $(0,0)$ to $(\ell,\ell)$ by the moves given in Table \[pathrules\].

   Direction                  From              affect their attitude in the classroom. Don’t be afraid to “geek out” with your students. Tell them what things thrill you about your subject, share new research or news in your field, and let them know how passionate you are about teaching them, too. Your attitude will be infectious!


very pleasant Asian girl said she was Seadiver 262 attending Oxford's Lady Margaret College. Driving through Aylesbury, she recognized the road name from LP sleeves and wanted to meet the man she'd been corresponding with these past months. Her name was Benazir Bhutto, the future Pakistan prime minister who was assassinated on December 27, 2007. He favorite Mott song was "All the Way From Memphis."Na has by and large avoided this tournament since then, but the last time he teed it up at TPC San Antonio he did scrape together a Top 20 finish, so maybe he’s exorcised the demons a bit. He disappointed a lot of people (ok, maybe just me) at the Heritage last weekend but he rallied back from a lackluster first round to shoot a 69 on Friday and just miss the cut by a shot. I’ll take a mulligan and utilize him in DraftKings lineups once again.

Scott Piercy – 70/1, $7,400

Brandon Harkins – 160/1, $7,300

Tom Hoge – 160/1, $7,000

Here’s a trio of cheaper longshots that I’ll have my eye on this weekend. Scott Piercy’s futures odds are a bit inflated but I love his DraftKings price this


(Pilokarpin, Ophtha AS, Norway) in both groups.

The "epithelium-on" CXL was performed without epithelial debridement. Two drops of local anesthetic proparacaine 0.5% (Alcaine, Alcon Norway AS), preserved by 0.001% BAC, and two drops of local antibiotic gentamycin 0.3% (Garamycin, Schering-Plough AS, Norway), preserved by 0.005% BAC, were applied to the cornea, one drop every minute for the initial five minutes. Thereafter, two drops of proparacaine and two drops of hypotonic 0.5% aqueous riboflavin solution without dextran (Vitamin B2; Streuli, Uznach, Switzerland) were applied alternating every 30 seconds until the riboflavin saturation was verified by the slit-lamp inspection of the cornea and by determination of presence of riboflavin flare in the anterior chamber.

In the "epithelium-off" group, the epithelium was removed in a diameter of 8 mm with an Amoils-epithelial scrubber (Innovativeand its stem cells from UVA radiation.

The cornea was subjected to UVA radiation with a wavelength of 365 nm at a working distance of 5 cm for 30 minutes. The UV-X lamp (IROC AG, Zürich, Switzerland) provided an irradiance of 3 mW/cm within a circular diameter of 9 mm. During the irradiation, BSS was applied every three minutes and proparacaine drops were added as needed.

After the UVA irradiation, two drops of atropine 1% (Atropine minims, Chauvin, England) and 2 drops of gentamycin were applied. The cornea was protected with a soft bandage contact lens for 12--18 hours for group 1 and for one week for group 2. Instructions were given to apply a mixture of 0.1% dexamethasone and 0.5% chloramphenicol (Spersadex med Kloramfenikol, Novartis, Norway) eye drops four times daily for one


both "epithelium-off" CXL \[[@B9], [@B11]\] and "epithelium-on" CXL \[[@B20]\]. As all previous reports applied 0.1% riboflavin, we speculate that use of 0.5% riboflavin solution may have caused the decrease in effect of CXL in the current study. One possible rationale for this is the increased use of oxygen by riboflavin due to its higher concentration in the stroma. Richoz et al. \[[@B39]\] recently revealed that the removal of oxygen after 30 seconds of irradiation essentially halts the photopolymerization process in CXL. They concluded that CXL requires oxygen in sufficient quantities to participate in the reaction. It is conceivable that when CXL is performed with 0.1% riboflavin, the supply of oxygen balances its consumption and allows the CXL process to continue. In contrast, the increased riboflavin concentration in thestudy showed no difference in safety and efficacy between the "epithelium-on" and the "epithelium-off" CXL using a protocol that ensures corneal saturation with 0.5% hypotonic riboflavin solution. However, efficacy in reversing topography features of keratoconus with use of 0.5% hypotonic riboflavin seems to be lower compared to the reported results with "standard" 0.1% riboflavin.

The authors have no financial, professional, or personal competing interests in connection with any of the materials mentioned in this paper. The SynsLaser Surgery AS and the Norwegian Research Council supported this research. No additional external funding was received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the paper.

Conflict of Interests
=====================

The authors declare that there is no conflict of interests regarding the