  return components.getLast();
}

void MultiDocumentPanel::setActiveDocument (Component* component)
{
    jassert (component != nullptr);

    if (mode == FloatingWindows)
    {
        component = getContainerComp (component);

        if (component != nullptr)
            component->toFront (true);
    }
    else if (tabComponent != nullptr)
    {
        jassert (components.indexOf (component) >= 0);

        for (int i = tabComponent->getNumTabs(); --i >= 0;)
        {
            if (tabComponent->getTabContentComponent (i) == component)
 ---
author:
- 'A. Liakos'
date: 'Received September XX, 2017; accepted March XX, 2017'
title: Asteroseismology of $Kepler$ Algol type oscillating eclipsing binaries
---

[This research paper contains light curve modelling, spectroscopy and detailed asteroseismic studies for four out of five in total semidetached eclipsing binaries with a $\delta$ Scuti component, that have been detected to date through $Kepler$ mission, namely KIC 06669809, KIC 10581918, KIC 10619109 and KIC 11175495.]{} [The goal is to study the pulsational characteristics of the oscillating stars of the systems as well as to estimate their absolute parameters and enrich the so far poor sample of this kind of systems.]{} [Ground based spectroscopic observations provide the means to estimate the spectral types of the primary components and to model the light curves with higher certainty. The photometric data are analysed using eclipsing binary modeling


that makes frequencies with amplitudes of tens of $\upmu$mag feasible to be detected [e.g. @MUR13], (b) the continuous monitoring of the targets, that eliminates the effect of alias in frequencies detections [@BRE00], and (c) the relatively high time resolution of the short-cadence data ($\sim1$ min). It should to be noted that the long-cadence data (i.e. time resolution $\sim30$ min) can be also considered extremely valuable for asteroseismology in cases of other pulsating stars such as Cepheids, $\gamma$ Doradus etc., which show pulsation periods of the order of several hours to several days. In addition, long-cadence data for targets observed during many quarters of the mission allow the study of short term pulsation period changes (e.g. order of a few years). Another very important point is that all the archives of theKIC 11175495 are shifted vertically for better viewing.[]{data-label="fig:qs"}](q_search.eps){width="\columnwidth"}

The analyses of the systems confronted three main problems: (a) the spot migration over time, which did not allow to create one simple LC model using all the available points, (b) the widely known ‘unrealistic’ error estimation of PHOEBE, and (c) the LC asymmetries due to pulsations. At this point it should to be noted that the objectives of the LC modelling are the estimation of the systems’ parameters (geometrical and absolute) and also the elimination of the binarity influence to the data points in order to be used later for a frequency analysis. A plausible solution to the first two problems was to solve each LC separately, while for the third one, to use again mean points but this time


photospheric spot was assumed, while two cool spots were used to describe the brightness changes of KIC 105. For KIC 106 two bright spots were assumed on the secondary’s surface because the system presents flare activity [@GAO16] and wide bright regions are expected. In Table \[tab:spots\] are given all the spot parameters, namely co-latitude ($co-lat.$), longitude ($long.$), radius, and temperature factor ($Tf$) for each LC. As representative beginning time of the spot migration is the half value of the EB’s period. Then, every successive timing is derived from the previous timing plus the EB’s period. The upper parts of Figs \[fig:spotKIC066\]-\[fig:spotKIC111\] show the changes of the parameters of all spots over time for each system, while the lower parts show the spot on the secondaries’ surfaces during the first and last days 0.259(3)
  $r_{\rm point}$                      0.423(1)         0.383(1)        0.214(1)         0.298(1)        0.242(1)        0.308(1)        0.141(4)         0.377(4)
  $r_{\rm side}$                       0.400(1)         0.275(1)


problem is more obvious when reaching the last significant frequencies. In order to solve this problem and provide more realistic S/N for the detected frequencies, the background noise ($bgd$) of each data set was calculated and listed in Table \[tab:PulsPar\] in regions where no frequencies seem to exist with a spacing of 2 cycle d$^{-1}$ and a box size of 2. The software has a critical limit of 4$\upsigma$ (i.e. S/N$>4$) to detect reliable frequencies, so the same threshold was adopted and is given for each system in Table \[tab:PulsPar\]. In the same table, the Nyquist number ($Nyq.$) and the frequency resolutions ($\updelta f$) according to the Rayleigh-Criterion (i.e. 1.5/$T$, where $T$ is the observations time range in days) are also given for each data set. Finally, after the first frequency computationin Fig. \[fig:MR\].[]{data-label="fig:HR"}](MR.eps){width="\columnwidth"}

![Location of the components of all studied systems within the H-R diagram. Symbols and lines have the same meaning as in Fig. \[fig:MR\].[]{data-label="fig:HR"}](HR.eps){width="\columnwidth"}

Although none of the systems exhibit total eclipses, which can be potentially used for the determination of the pulsating component (i.e. occurrence/absence of pulsations during the flat-phase part of the total eclipse), the primaries of all systems are A-F type stars according to the present spectral classification, thus, they fit better to a profile of a $\delta$ Scuti star in comparison with the secondaries, which are much cooler. Therefore, it is plausibly concluded that, in combination with the previous results for their evolutionary stages, all systems can be considered by definition as oEA stars. Three independent $p$-mode frequencies in the range 23-38 cycle d$^{-1}$ were found for the primary


there is a large scatter between 1.2 d$<P_{\rm orb}<$2.6 d (i.e. $0.08<\log P_{\rm orb}<0.42$) and 6.4 cycle d$^{-1}<f_{\rm dom}<64.5$ cycle d$^{-1}$ (i.e. $-1.81<\log P_{\rm pul}<-0.81$) for unknown reasons so far.

In Fig. \[fig:gP\] the locations of the primaries of the studied systems and other of oEA stars within the $\log g - \log P_{\rm pul}$ diagram are also shown. Contrary to the previous empirical fit, in this case the contribution of the systems to a new empirical relation between $\log g - \log P_{\rm pul}$ is quite significant. The previous fit [@LIAN17 eq. 7] included all the known systems with a $\delta$ Scuti component, whose absolute parameters are known, regardless their Roche geometry. In the present study and for the following empirical correlation, only the oEA stars are taken into account. The four studied systems consist the $\sim7$%Long-term heart-specific mortality among 347 476 breast cancer patients treated with radiotherapy or chemotherapy: a registry-based cohort study.
Breast cancer survival has improved throughout the last decades, but treatment-induced cardiotoxicity remains a major concern. This study aimed to investigate competing causes of death and prognostic factors within a large cohort of breast cancer patients and to describe the heart-specific mortality in relation to the general population. In this registry-based cohort study, women diagnosed with breast cancer between 2000 and 2011, who were treated with radiotherapy or chemotherapy and followed until 2014, were identified from the Surveillance, Epidemiology, and End Results-18 (SEER-18) database. Cumulative mortality functions were computed. To investigate heart-specific mortality relative to the general population, long-term (≥10 years) standardized mortality ratios (SMRs) were calculated. Prognostic factors for heart-specific


plasma, during the hospitalization were also recorded.

2.2 Definition of abnormal liver function {#sec008}
-----------------------------------------

As there was no laboratory reference interval for underage patients in China \[[@pone.0224352.ref015]\], the adults' reference intervals for common clinical biochemistry tests were used for reference to define the liver function of underage inpatients temporarily. The reference intervals in Xiangya Hospital, which are based on the reference intervals of adults \[[@pone.0224352.ref015]\], are ALT, male (9--50 U/L), female (7--40 U/L); AST, male (15--40 U/L), female (13--35 U/L); total bilirubin (TBil), 1.7--17.1 μmol/L; direct bilirubin (DBil), 0--6.8 μmol/L; alkaline phosphatase (ALP), 45--125 U/L.

Definition of abnormal liver function: at least one of ALT, AST, ALP, TBil and DBil was above the upper limit (ULN) of the reference value. Abnormal liver function was graded by classification criteria in NCI.CTC v4.03                                    8.3 (7.4)     9.6 (8.9)

\* The highest liver function laboratory indexes during the IMP administration should be chosen.

3.2 Abnormal liver function in 108 patients {#sec014}
-------------------------------------------

108 of 188 patients had abnormal liver function after IMP administration. [Table 3](#pone.0224352.t003){ref-type="table"} showed the classification of abnormal liver function and the general situation of the 108 patients. The physiological status of 108 patients with abnormal liver function was poor, and the common complications were pulmonary infection (45.4%), septicemia (32.4%) and sepsis (13.0%). None drug withdrawal was due to abnormal liver function.

10.1371/journal.pone.0224352.t003

###### Abnormal liver function


infection and cystitis. The cases of such patients were small, so they were analyzed together.

3.3 Probability distribution of MVID {#sec015}
------------------------------------

As was shown in [Fig 2](#pone.0224352.g002){ref-type="fig"}, the probability distribution of the MVID of DBil and TBil was a symmetric distribution with a mean value of 0. However, in the probability distribution of AST and ALT, the curve was not symmetric around 'x = 0', but a positive deviation distribution. In [Fig 2D](#pone.0224352.g002){ref-type="fig"}, the area under the curve (AUC) of both sides was calculated. In the probability distribution curve of AST, the left AUC was 0.38, and the right was 0.62. On the right of 'X = 42', its probability distribution curve showed a significant increase trend, while between 'X = 0' and 'X = 42', it is still symmetricalfunction, the MVID of AST was less than 0 in the remaining 13 patients. 14 patients of the MVID of ALT was less than 0 after administration. The remaining 2 patients were also significantly reduced.

![**The distribution of MVID after intervention of liver protecting drugs (A. ALT; B. AST).** The "y = 0" was marked by a dotted line. From top to bottom, the three solid horizontal lines respectively represent the maximum MVID, the median MVID and the minimum MVID. The number of patients and the median value of MVID were respectively marked above the top line or the middle line. A+B and A+C represented combination therapy.](pone.0224352.g003){#pone.0224352.g003}

After using liver protecting drugs, the MVID of AST in 81.3% (13/16) underage patients and the MVID of ALT in 87.5% (14/16) underage


including special populations such as children and pregnant women in clinical trials. In the real world, the applicability of clinical trial results of general population to the special population remains to be verified. Therefore, the safety of drugs for special populations still needs to be studied and analyzed in daily clinical practice.

In a retrospective study of clinical data, principle of control is regularly used to determine whether the exposure factor has a statistically significant effect on clinical outcomes. However, in the clinical medication data, the heterogeneity of basic status and dosing regimen of each patient (the poor basic status of some patients and the existence of multiple infections) will lead to inconsistent data standards and huge data noise. The accuracy of the analysis results of traditional statistical methodsor bisexual people and that the Bakery would not have objected to a cake carrying the message “Support Heterosexual Marriage” or “Support Marriage”. It also held that the reason that the order was cancelled was that the Bakery would not provide a cake with a message supporting a right to marry for those of a particular sexual orientation. Therefore, it found it to be a case of association with the gay and bisexual community, with the protected characteristic being the sexual orientation of that community and could, therefore, amount to direct discrimination.

An Infringement of Human Rights?

Mr & Mrs McArthur argued that it is a breach of their Human Rights to require them to provide a service that is contrary to their religious beliefs and, in particular, Article 9,


You will keep up with your rivals.

According to Social Times, around 90% of companies use multiple social platforms to make their sales bigger.
If you are not among those ninety percent yet, we highly recommend you getting an account in order to keep up with the latest trends. Otherwise, your rivals will have access to clients you cannot reach.

7. It makes all businesses equal.

Social network is a platform where all the businesses start at the same level. Thus, everyone has an equal chance to succeed and attract more clients through such channels.
All you need to do is to deliver valuable information in a fun and entertaining way as well as establish your brand as the most trustworthy among numerous choices available. So, if you want to increase your revenue,ad networks the expansive influence will imply that more medium size and small publishers will scrutinize the esteem they are giving. The outcome will be the ad networks will enter a winding of decline.

4. Ads Get Bigger and More Intrusive

Ad networks, which are generally keep running by individuals with traditional advertising backgrounds, are reacting to their declining fortunes by making greater and more intrusive ads. Fortune.com has had a full screen, "over-the-page" ad that covers their homepage for quite a while, yet now even sites like Techcrunch are trialing them. Aside from spam emails, there is no other adverting group that bothers and pesters Internet clients more. Ideally this is a passing Trend, once publishers and advertisers realize that irritating their audience is no real way to build


impact on clinical practice, need to be explored. However, water replacement by oral nutritional support should take advantage of the patients' attitude to assuming a greater fluid intake, limiting at the same time fluid overload during the refeeding phase.[Considerations in determining indication for valvular surgery].
Between 1970 and 1987 valvular operations with cardiopulmonary bypass were performed on 636 patients, with an overall early mortality of 7.5%. To determine the critical indication for valvular surgery, preoperative clinical characteristics were examined by comparing 35 patients, who had died of surgery because of low cardiac output syndrome or multiple organ failure, with operative survivors. The multivariable logistic analyses demonstrated that NYHA functional class IV, multiple valvular disease, large CTR more than 70%, high left ventricular end-diastolic pressure more than 15 mmHg, depressed left ventricular ejection fraction less than 40%, and renal and hepatic dysfunction were powerful independent clinical characteristics concerning operative mortality. The mortality was highly significant when a patient was associated with more than three of the above factors


northward in the Northern Hemisphere, and further south in the Southern Hemisphere \[[@CR12]\]. The change in land use might also play a relevant role, especially for some important allergenic species, such as grasses. However, since most data come from the analysis of distribution of airborne pollen, these findings are potentially biased by the occurrence of long and medium distance transport episodes of allergenic pollen \[[@CR13], [@CR14]\].

Pollen allergy is frequently used to study the interrelationship between air pollution and allergic respiratory diseases (rhinitis and asthma).

Epidemiologic studies have demonstrated that urbanization, high levels of vehicle emissions and westernized lifestyle are correlated with an increase in the frequency of pollen-induced respiratory allergy in people who live in urban areas compared to those who live in rural areas \[[@CR15]\]. Studies on plantBy attaching to the surface of pollen grains and plant-derived particles of paucimicronic size, air pollutants could modify not only the morphology of these antigen-carrying agents but also their allergenic potential. In addition, by inducing airway inflammation, which increases airway permeability, pollutants overcome the mucosal barrier and could be responsible for "priming" the allergen-induced responses of pollinosis in allergic and atopic individuals.

The relationship between exposure to air pollution and the development of allergic respiratory diseases has been investigated in several studies, however there is still much to understand.

Nicolai and von Mutius carried out a study on this topic in reunified Germany. The prevalence of asthma and allergic disorders was assessed in East Germany and in West Germany \[[@CR32]\]. In East Germany the main sources of air pollution were


climate, and secondary prevention by clinical intervention to minimize climate change--related increases in asthma and allergic disease \[[@CR61]\]. In the future climate changes may depend on how rapidly and successfully global mitigation and adaptation strategies are deployed. The effect of human intervention and efforts to minimize changes in vegetation and aeroallergen exposure remains to be seen.

Reducing air pollution might contribute to lessening the impact of climate change on pollen and thus directly on patients, while recognizing that ozone, the key pollutant associated with climate change, may be the major driver of pollutant/pollen interactions.

What can we do to decrease the effects of environmental factors affecting respiratory allergic diseases? Suggested measures are as follows: encouraging policies to promote access to non-polluting sources of energy; reducing the private traffic in townsand improving public transport; decreasing the use of fossil fuels and controlling vehicle emissions; planting non-allergenic trees in cities, and in this context the proposed implantation of new trees should be evaluated by allergy specialists in order to avoid high allergenic species. Although in this paper the direct impact of the increase in plant growth on allergy has not been dealt with, more studies are needed to assess its contribution to the increase in allergy prevalence.

Many measures to reduce greenhouse gas emissions may have positive benefits for health. These co-benefits will offset at least some of the costs of climate change mitigation and should be taken into account in international negotiations (Table [2](#Tab2){ref-type="table"}). Strategies to reduce climate changes and air pollution are political in nature, but citizen and in


TV said Friday. The shelling underscored deep fears in government strongholds that rebels will escalate attacks in an attempt to disrupt the balloting.

Assad is expected to win a third, seven-year mandate in the vote scheduled for June 3, but the West and opposition activists have criticized it as a farce since it is taking place despite a raging civil war. The 49-year-old president has not made a public appearance in more than a month and was not at the gathering struck by the mortar shell late Thursday in the southern city of Daraa. But campaigning has begun in earnest, with supporters waving his pictures and Syrian flags during daily demonstrations in the capital, Damascus, the coastal city of Latakia and other government-held areas.

Many gatherings have been held incontrol: 10 omega (3-12 omega) p = 0.031. These data suggest that when administered during a procedure in which thrombus has occurred, aggregation may be rapidly arrested. This applies to quiescent platelets but also activated platelets undergoing aggregation.


witch!" "How do you know?" "Am I allowed to say something?" " Please." " I know that face." "She would not be one of your angels in the Florida chapel, would she?" "Yes, she is." "You're dangerously perceptive." "This is probably a very naive but I am a man of the cloth." "Do you?" "Do you painters not become very intimate with your models?" "It must be very... tempting... when you spend hours and hours alone with, not only beautiful, but young girl." "Would you like me to include your hands in the portrait?" " I'll leave that up to you." " No, it's up to you to decide." "Hands are not easy to paint and not everybody will spend the extra money." "Well, what is the difference?"name." "He's a heretic spreading these diabolical ideas to poison the souls of God- fearing people." "If you hear somebody talking about 'The Temple', instead of 'The Church', he is either a Judaiser, or, even worse, a Protestant." "Get his name." "If you are in a public place and see a man hiding his penis with his hand while urinating the man is probably circumcised." "And he's a Judaiser!" "I am giving you just a few examples of what to look for, whom to identify." "Bring their names to the attention of Holy Office." "Your eyes, your ears, your brain." "They are the servants of God." "Come on, Inés." "Taste it, it's good." "Come on." " Hey, where are you going?" " Oh, she's going to the dwarf."


notified immediately." "Well, certainly." "Oh, incidentally," "I have not yet been paid for the painting." "If we find him, we'll remind him." "As the image of the man vanishes into thin air... may his name forever vanish from all memory." "Whosoever pronounces his name may he burn in the fires of eternal damnation." "She will like this frame." "You've done beautiful work." "I've never been this close to our Queen." "But... is she really that ugly?" "What's your point?" "It's a beautiful painting." "Yes, but that does not make a Queen beautiful." "Don Francisco," "Her Majesty wishes for you to go to His Majesty's chamber." "Please, sit." "Sit, please." "Please, sit" "How did you like it?" "Very much, Your Majesty." "Very much." " Are you telling me thehow terribly wrong I had been all my life." "Reading..." "Reading Voltaire, Rousseau..." "Meeting Danton." "Look," "I was baptized again." "I shed blood for the Revolution." " A nasty wound." " And I even got married there." "Yes, Henrietta, my wife." "I love her..." "And I have three children." "Yes, I who took the vows of celibacy." "So you will have to paint my portrait with the whole family." "That's..." "That's ten hands to paint." "Ten." "And I can afford them all now." "Come in." "Inés." " This is Lorenzo..." " Casamares." "Lorenzo Casamares." "What can I do for you, miss?" "Don't, no, no, please, stop this, stop." "Stop, please." "Sit down." "Sit." "Just tell me what do you need?" "What can I do for you?" "What happened


does have a daughter." "How do you know?" " I saw her." " You saw her?" "Yes." "Did you talk to her?" "No, no, I just saw her." "How do you know that the girl you saw is Inés's daughter?" "She looked exactly like her mother did when I painted her 16 years ago." " She was, it was a perfect replica." " Where did you see her?" "In the Pardo Gardens." " In the Gardens?" " Yes." "She is a?" "Yes, she is." "Do you know her name?" " Alicia." " Alicia." "Do you think you could bring Inés to my house?" "I want the mother to meet her daughter." "Of course." "Come on." " Is your name Alicia?" " Yes." "Where were you born, Alicia?" "Inis higher than God and that the words of the Gospels are nothing but lies and poison." "You must never never be allowed to repeat your crimes." "Therefore, the Church declares you guilty, and your punishment will be death." "But if you repent publicly, the merciful hand of the Church will spare your life." "Your body will be saved, and even your soul, if you join us again in the ever- loving arms of God." "Lorenzo, my son," "will you repent?" "No, I'm sure." " In the name of the Father..." " God will forgive your sins." "You have lost your sight, Brother." "Open your eyes." "Lorenzo!" "Lorenzo!" "Lorenzo!" "Over here!" "Well, what do you think's going to happen to him now?" "Brother, repent." "You still have time


light intensity ranged from 25,000 to 40,000lux. In addition, the spectrum of the sunlight is across most of the electromagnetic spectrum, spanning a range of 200nm to about 1mm.

### Experiment B {#sec007}

To examine whether the early life exposure to sunlight would associate with the onset of refractive errors, all of the helmets were removed after the last biometry measurements of experiment A, at approximately 215±3 days of age. Then, the monkeys regained unrestricted vision and were raised in the same laboratory room (without exposure to outdoor light) until they were about 3 years old (1185 ± 3 days of age). That age in monkeys can be considered to be equivalent to 12 years of age in humans, well into the age range when school myopia frequently develops inthe mean±SD.**

However, it is interesting that the absolute anisometropia (i.e. the difference of maximum and minimum refraction) in 3-year-old monkeys that were treated by monocular hyperopic-defocus during infancy under artificial lighting was significantly greater and more myopic than that in monkeys in the NL group (AL vs NL: -1.66±0.87D vs -0.22±0.44D; P = 0.002) or the 3-year-old control group (AL vs Control: -1.66±0.87D vs -0.05±0.85D; P\<0.0001) at the same 3-year-old end-point. As illustrated in [Fig 3](#pone.0127863.g003){ref-type="fig"}, which shows the ametropia for the right eye and left eye of each animal at the age of 3 years, three of four animals in the AL group demonstrated absolute myopic anisometropia more than 1.75D: two of these developed relative myopia in the originally lens-induced eye, but the other developed myopia in


spectacles under sunlight for only 3 hours per day for 190 days (the duration of effective outdoor exposure suggested by the study of Rose et al\[[@pone.0127863.ref018]\]) induced significantly more hyperopia than those under artificial lighting, which is now considered to correlate with a lower incidence of myopia. Moreover, we observed different patterns over time, involving compensation to imposed anisometropia between the two groups, as 75% AL animals developed myopia more than -2.0D, whereas, most NL animals remained isometropic. Nevertheless, this difference was not statistically significant. Finally, these changes in refractive error were correlated with the rate and final extent of vitreous chamber growth, as reported previously in other animal studies. Overall, these findings provide support for the conclusion that daily exposure to natural light (sunlight) tends to inhibitduring which detrimental visual experience can disrupt the normal developmental process and induce long-lasting response deficits in visual function. Several lines of evidence show that the defocus differentiation and visual signal transduction processes involved in regulating refraction development and ocular growth are located mainly, if not exclusively, in the retina\[[@pone.0127863.ref049]--[@pone.0127863.ref052]\], where the sensitive periods of visual development are relatively short. For example, in rhesus monkeys, development of the basic spectral sensitivity functions of rods and cones ends at 3 months and 6 months of age, respectively\[[@pone.0127863.ref053]\]. Therefore, in our study the unilateral lens-rearing regimen was likely to cover the sensitive period of retinal function that is critical for accurate response to optical defocus, and this resulted in interocular imbalance of refractive state in later life.

On the other hand,


that. I think the problem is then conflating that with Germany's poor world cup performance. He's been used as a scapegoat.

"Excuse my dust.""It put me back in my place and made me realize, yes I'm just a cunt in a clown suit.""The world will little note, nor long remember what we say here, but it can never forget what they did here"

Goat Boy wrote:I can understand Ozil’s reasoning for meeting Erdogan and I don’t doubt his explanation but it was a naive decision given what is going on in that country. Not being German I don’t have much of an opinion past that because I don’t know enough about the context.

I think he received justified criticism for that. I think the problem is then conflating that with Germany'sscapegoat.

Perhaps he is but whether it’s racist, I dunno.

I’d like to read some German perspectives.

What does Boris Becker think?

Well it seems from his statement that he’s had racist abuse from fans and perhaps experienced discriminatory treatment from up on high too, in which case I think his reaction is brave and justified.

When the Swedish winger Durmaz was racially abused after the Germany game, the team and FA spoke out and supported him whereas nothing like that seems to have happened with Özil.

But then again if he is just having a go at the FA for being critical of his Erdogan hangout then sorry, they were right about that. Doesn’t excuse any other racism he’s experienced of course.

fange wrote:One of the things i really dislike in this life is


for being critical of his Erdogan hangout then sorry, they were right about that. Doesn’t excuse any other racism he’s experienced of course.

Well you’ll always get the idiots crawling out of the woodwork, especially these days. If the DFB weren’t more supportive in public then I agree that’s not good enough, especially when some were using Ozil’s and Gundogans meeting with Erdogan for nefarious far right purposes.

Grindel has made some statements in the past about multiculturalism but I can’t find the original context. One could infer certain attitudes from this (there is a quote about multiculturalism being a “lie”).

Whether there was something darker going on from Grindel in picking out Ozil I dunno, maybe him and Bierhoff simply saw it as expedient to protect their own arses. IAn insight into the performance of benthic classification indices tested in Eastern Mediterranean coastal waters.
This work evaluates four indices that have been used for benthic macroinvertebrate ecological quality classification in the Mediterranean Sea. Our study was based on the data obtained from the participation of Greece and Cyprus in the Mediterranean Geographical Intercalibration group. The indices AMBI, M-AMBI, MEDOCC and BENTIX were applied to the available benthic species data, and the succession of the ecological groups along the graded values of each index was plotted. The level of agreement among methods was calculated, and the performance of each method in estimating ecological quality status was evaluated. AMBI, based on the Atlantic model, and its derivative M-AMBI overestimated the statuses, while MEDOCC showed the best level of agreement with


control autoimmune disease, which is triggered by a ceramide-mediated induction of cell death in CF organs. Autoimmunity becomes in particular overt in cystic fibrosis mice lacking iNKT cells and although suppression of the autoimmune response by iNKT cells is beneficial, IL-17(+) iNKT cells attract macrophages and neutrophils to CF lungs resulting in chronic inflammation. Genetic deletion of iNKT cells in cystic fibrosis mice prevents inflammation in CF lungs. Our data demonstrate an important function of iNKT cells in the chronic inflammation affecting cystic fibrosis lungs. iNKT cells suppress the auto-immune response induced by ceramide-mediated death of epithelial cells in CF lungs, but also induce a chronic pulmonary inflammation.method, any two adjacent signal paths among signal paths 11 or gate signal paths 12 are connected to different groups of shorting bars, and any short defects between any two adjacent signal paths can be screened out.
There are often short defects between two adjacent signal paths during the manufacturing process of array cells. The testing method in FIG. 3 is an effective way to screen out those short defects between two adjacent signal paths but only suitable for the array testing of LCD devices. During the manufacturing process of liquid crystal cells, color filters are coupled with the substrate and liquid crystal molecules are injected into the substrate. Thus, the testing signals are converted through the liquid crystal cells into light signals and further into light with red,


The present invention relates to liquid tight conduit fittings and, more particularly, to liquid tight conduit fittings used to terminate flexible conduit to electrical enclosures.
Liquid tight conduit fittings are commonly used to terminate an end extent of a length of flexible conduit to an electrical enclosure such as a junction box. It will be appreciated that such conduit fittings, which are often formed from a plastic material such as UV resistant PVC, may be used in both exterior and interior applications. The fittings must be able to withstand certain environmental and/or physical conditions without failure.
One such category of fittings is used to provide a liquid tight connection between a section of type B liquid tight conduit and an electrical enclosure. Usage applications include exterior air conditioning wiring, swimmingpool pumps, hot tubs, compressors, outdoor lighting, heat pumps or any other application requiring electrical service of 600 VAC or less and which is not subject to high levels of physical abuse. It will be appreciated that such fittings may also be used in machine tool environments.
Prior art conduit fittings include a gland end having a helical rib formed about the outer surface thereof. This gland end is inserted into an end extent of flexible conduit via a twisting process. A bushing and/or sleeve is positioned proximate the terminating end of the conduit to assist in preventing ingress of moisture into the interior of the conduit. Moreover, the terminating end of the conduit, which has often been cut by the installer and may include uneven and/or unsightly edges,


the brain.

Their plight became better known after the 1992 movie about a couple who, desperate for a cure for their son, developed a treatment from olive and rapeseed oils that seemed to help him. The real life Lorenzo died in 2008 at age 30, having lived two decades longer than doctors predicted.

Lorenzo’s oil did not turn out to be a cure. The only effective treatment is a stem cell transplant from a matched sibling, but only about 1 in 5 boys with the disease have such a donor.

The gene therapy tested a way for boys to serve as their own cell donors.

Doctors remove some of the patient’s blood stem cells, modify them in the lab to carry the healthy gene and give them back intravenously.

Before the modified cellsof vulgar language or racial slurs, will be banned. Please be respectful of the opinions of others and keep the conversation on topic and civil. If you see an inappropriate comment, please flag it for our moderators to review.


Ireland and how these affect behaviour.

The Crisis Pregnancy Agency (CPA) and the sexual-health sector in general need robust evidence in order to develop sexual-health policies, to plan strategies and to inform the effective promotion of sexual-health messages. The ISSHR findings will be invaluable not only to the work of the CPA in preventing crisis pregnancy, but also to that of other organisations concerned with promoting sexual health, providing sexual-health services, preventing sexually transmitted infections, and providing sex education for young people.the error is probably output to stderr, so either do 2>error.log to redirect stderr to the file, or &>error.log to redirect both to the file. If the latter does not work, you are maybe not using Bash and >error.log 2>&1 will do the same. (the order is important for the last one)


More Information

Flying Oil

$8.00

Flying Oil is based off of the old European "flying ointment" and contains mugwort, anise and other entheogenic herbs that act as powerful allies in spirit work, astral travel, hag riding and shamanic journeywork. Caution: this blend includes potentially toxic herbs and is not intended to be used on the body.

Flying Oil Uses:

Facilitates out-of-body and astral travel

Enhance visual imagery during meditation or shamanic work

Enhance hag-riding skills when tormenting enemies

Flying Spell Ideas:

Dress purple candles with Flying Oil, roll them through ground wormwood leaf, and burn them by your side when performing shamanic journeywork, hag riding, out-of-body or astral travel. Anoint sacred objects with Flying Oil to assist you in your spiritual work. Flying Oil contains many herbs sacred to "witches" and would be perfect for any useOF THE INVENTION

Microprocessors, as is well-known in the art, are integrated circuit (IC) devices that are enabled to execute code sequences which may be generalized as software. In the execution most microprocessors are capable of both logic and arithmetic operations, and typically modern microprocessors have on-chip resources (functional units) for such processing.

Microprocessors in their execution of software strings typically operate on data that is stored in memory. This data needs to be brought into the memory before the processing is done, and sometimes needs to be sent out to a device that needs it after its processing.

There are in the state-of-the-art two well-known mechanisms to bring data into the memory and send it out to a device when necessary. One mechanism is loading and storing the data through


embodiment of the present invention.

DESCRIPTION OF THE PREFERRED EMBODIMENTS

FIG. 1 is a simplified diagram of memory management in a system 104 comprising a processor 100 and a memory 102 in communication with a device 106. In this example it is necessary to bring data from device 106 into memory 102 for processing, and sometimes to transmit processed data from memory 102 to device 106, if necessary. Management in this prior art example is by processor 100, which sends I/O commands to and receives responses and/or interrupts from device 106 via path 108 to manage movement of data between device 106 and memory 102 by path 110. The processor has to determine whether a data structure can fit into available space in memory, and has to decide where into learned results of operation as previously described above. A factor defining this ongoing determination is termed EnableVector[VPSize].

The above-described factors always remain in an undefined state for any block managed by software instead of hardware.

2) Block selection: The blocks with the smallest virtual page (enabled or not) that is able to fit the data packet in are candidates. The block with the smallest enabled virtual page is selected.

If Fits[j] = FALSE for all j Then

<Packet does not fit in hardware-controlled

memory>

Else

C = set of blocks with smallest MinVPS AND

Fits[MinVPS]

B = block# in C with the smallest enabled virtual

page

(if more than one exists, pick the smallest

block number)

If one or more blocks in C have virtual pages enabled

Then

Index = VPIndex[B]

VPSize = MinVPS[B]

NumAPs = ceil(S/256)

packetPage = (B*64KB + Index*VPSize) >>

8

Else

<Packet does not


in the 512-byte column has changed indicating that block as the next available 512-byte VP for a next packet of that size or smaller. Referring now to FIG. 7d, an absence of cross-hatching indicates that Block 1 was not selected for packet storage in the current cycle.

Referring now to FIG. 8a, the sequence now must deal with fits determination and allocation for a 1 KB data packet as is indicated above Block 0. In this example, the previous activity described with reference to FIGS. 7a (256-byte) and 7c (512-byte) is illustrated herein as double crosshatched blocks indicating past allocation and current ineligibility for consideration in this current cycle. It is also noted that neither column (1 KB) nor column (2 KB) is enabled. Even though a 1 KBconfiguration possibilities.

FIG. 11 is a process flow chart illustrating logic steps for packet overflow upload according to an embodiment of the present invention. At step 5100, a packet management unit analogous to PMU 5004 described with reference to FIG. 10 is notified of the arrival of a data packet for processing. At this step, the data packet is in buffer in a system interface unit (SIU) and originates from one of existing input devices. At step 5101, PMU determines if the pending packet fits into local packet memory (LPM). The PMU is aware of the size of the packet and checks if there are any pages available within LPM to store the packet. This process is algorithmic in nature. A page memory management unit analogous to PMMU 5010


          slider_pos[5];  /*  positions for the five sliders  */

  gboolean       enable_preview_update;
  gboolean       sample_show_selection;
  gboolean       dst_show_selection;
  gboolean       sample_show_color;
  gboolean       dst_show_color;
} t_samp_interface;

typedef struct
{
  guchar  color[4];     /* R,G,B,A */
  gint32  sum_color;    /* nr. of sourcepixels with (nearly the same) color */
  void   *next;
} t_samp_color_elem;

typedef struct
{
  gint32              all_samples;  /* number of all source pixels with this  " The out_low/out_high levels constrain the resulting intensity index"
        " The intensity index is used to pick the corresponding color"
        " in the sample colortable. If hold_inten is FALSE the picked color"
        " is used 1:1 as resulting remap_color."
        " If hold_inten is TRUE The brightness of the picked color is adjusted"
        " back to the original intensity value (only hue and saturation are"
        " taken from the picked sample color)"
        " (or to the input level,


        g_values.lvl_in_gamma  = GIMP_VALUES_GET_DOUBLE      (args, 7);
          g_values.lvl_out_min   = GIMP_VALUES_GET_INT         (args, 8);
          g_values.lvl_out_max   = GIMP_VALUES_GET_INT         (args, 9);

          if (main_colorize (MC_GET_SAMPLE_COLORS) >= 0)
            {
              main_colorize (MC_DST_REMAP);
            }
                                 GIMP_RGBA_IMAGE,
                              allrowsbuf,
                              PREVIEW_SIZE_X * 4);
      gtk_widget_queue_draw (preview);
    }
}

static void
update_preview (GimpDrawable *drawable)
{
  t_GDRW   gdrw;
  gboolean is_drawable = FALSE;

  if (! drawable || !g_di.enable_preview_update)
    return;

  if (gimp_item_get_id (GIMP_ITEM (drawable)) ==


gdk_cairo_set_source_rgba (cr, border_color);
  cairo_stroke (cr);
}

static void
smp_get_colors (GtkWidget *dialog)
{
  gint   i;
  guchar buffer[3 * DA_WIDTH * GRADIENT_HEIGHT];

  update_preview (gimp_drawable_get_by_id (g_values.sample_id));

  if (dialog && main_colorize (MC_GET_SAMPLE_COLORS) >= 0)  /* do not colorize, just analyze sample colors */
    gtk_dialog_set_response_sensitive (GTK_DIALOG (g_di.dialog),
                                       GTK_RESPONSE_APPLY, TRUE);
  for (i = 0; i < GRADIENT_HEIGHT; i++)
    memcpy (buffer + i * 3 * DA_WIDTH, g_sample_color_tab, 3 * DA_WIDTH);

  update_preview (g_values.dst);

  gimp_preview_area_draw (GIMP_PREVIEW_AREA (g_di.sample_colortab_preview),
                      g_values.lvl_in_max);
  if (update & LOW_OUTPUT)
    gtk_adjustment_set_value (g_di.adj_lvl_out_min,
                              g_values.lvl_out_min);
  if (update & HIGH_OUTPUT)
    gtk_adjustment_set_value (g_di.adj_lvl_out_max,
                              g_values.lvl_out_max);
  if (update & INPUT_LEVELS)
    {
      guchar buffer[DA_WIDTH * GRADIENT_HEIGHT];
      for (i = 0; i < GRADIENT_HEIGHT; i++)


GDK_MOTION_NOTIFY\n");
      mevent = (GdkEventMotion *) event;
      x = mevent->x;
      gdk_event_request_motions (mevent);
      update = TRUE;
      break;

    default:
      if (g_Sdebug)
        g_printf ("EVENT: default\n");
      break;
    }

  if (update)
    {
      if (g_Sdebug)
        g_printf ("EVENT: ** update **\n");
      switch (g_di.active_slider)
        {
        case 0:  /*  low input  */
   G_CALLBACK (level_in_draw),
                    NULL);

  gtk_widget_show (vbox2);
  gtk_widget_show (frame);

  /*  The sample_colortable prevev  */
  frame = gtk_frame_new (NULL);

  vbox2 = gtk_box_new (GTK_ORIENTATION_VERTICAL, 2);
  gtk_container_add (GTK_CONTAINER (frame), vbox2);
  gtk_grid_attach (GTK_GRID (grid), frame, 3, ty, 2, 1);

  g_di.sample_colortab_preview = gimp_preview_area_new ();
  gtk_widget_set_halign (g_di.sample_colortab_preview, GTK_ALIGN_CENTER);
  gtk_widget_set_hexpand (g_di.sample_colortab_preview, TRUE);
  gtk_widget_set_size_request (g_di.sample_colortab_preview,
                               DA_WIDTH, GRADIENT_HEIGHT);
  gtk_box_pack_start (GTK_BOX (vbox2), g_di.sample_colortab_preview, FALSE, TRUE, 0);
  gtk_widget_show (g_di.sample_colortab_preview);

  /*  The levels


      r = (gint) col_ptr->color[0];
                      g = (gint) col_ptr->color[1];
                      b = (gint) col_ptr->color[2];
                    }

                  if (cnt > 20)
                    col_ptr = col_ptr->next;
     return;

  fprintf (fp, "sample_colorize: params\n");
  fprintf (fp, "g_values.hold_inten     :%d\n", (int)g_values.hold_inten);
  fprintf (fp, "g_values.orig_inten     :%d\n", (int)g_values.orig_inten);
  fprintf (fp, "g_values.rnd_subcolors  :%d\n", (int)g_values.rnd_subcolors);
  fprintf (fp, "g_values.guess_missing  :%d\n", (int)g_values.guess_missing);
  fprintf (fp, "g_values.lvl_in_min     :%d\n", (int)g_values.lvl_in_min);
  fprintf (fp, "g_values.lvl_in_max     :%d\n", (int)g_values.lvl_in_max);
  fprintf (fp, "g_values.lvl_in_gamma   :%f\n", g_values.lvl_in_gamma);
  fprintf (fp, "g_values.lvl_out_min    :%d\n", (int)g_values.lvl_out_min);
  fprintf (fp, "g_values.lvl_out_max    :%d\n", (int)g_values.lvl_out_max);

  fprintf (fp, "g_values.tol_col_err    :%f\n", g_values.tol_col_err);
}

/* -----------------------------
 * DEBUG print procedures END
 * -----------------------------
 */

/* DEBUG: read values from file */
static void
get_filevalues (void)
{
  FILE  *fp;
  gchar  buf[1000];

/*
  g_values.lvl_out_min = 0;
  g_values.lvl_out_max = 255;


  (color[1] == col_ptr->color[1]) &&
          (color[2] == col_ptr->color[2]))
        {
          col_ptr->sum_color++;
          return;
        }
    }

  /* alloc and init element for the new color  */
  col_ptr = new_samp_color (color);

  if (col_ptr != NULL)
    {
      /* add new color element as 1.st of the list */
      col_ptr->next = g_lum_tab[lum].col_ptr;
      g_lum_tab[lum].col_ptr = col_ptr;
    }
}

/* sort Sublists (color) by descending sum_color in g_lum_tab
    break;
                    }
                }

              div = idx - (lum -1);
              new_color[0] = lo_color[0] + ((float)(hi_color[0] - lo_color[0]) / div);
              new_color[1] = lo_color[1] + ((float)(hi_color[1] - lo_color[1]) / div);
              new_color[2] = lo_color[2] + ((float)(hi_color[2] - lo_color[2]) / div);

/*
 *


   g_lum_tab[lum].all_samples = 1;
    }

  g_free (f_samples);
}

static void
end_gdrw (t_GDRW *gdrw)
{
  t_GDRW *sel_gdrw = (t_GDRW *) gdrw->sel_gdrw;

  if (sel_gdrw && sel_gdrw->buffer)
    {
      g_object_unref (sel_gdrw->buffer);
      sel_gdrw->buffer = NULL;
    }

  g_object_unref (gdrw->buffer);
  gdrw->buffer = NULL;
}

static void
init_gdrw (t_GDRW       *gdrw,
           GimpDrawable *drawable,
           gboolean      shadow)
{
  GimpImage    *image;
  GimpDrawable *sel_channel;
  gint32        x1, x2, y1, y2;
  gint        so far so good! LOGAN5's tool works great. i'm signed into PSN and it didnt ask me to update.. people had trouble with games but i'll give a game a shot now, friends list, PSstore and all that works fine tho.

Okay this is lame. The only way I can get online with my 60gig PS3 that I paid $600 for when it was first released is to go through with this update to DOWNGRADE my console by taking away one of its features. Sony really needs to come better than this.

Okay this is lame. The only way I can get online with my 60gig PS3 that I paid $600 for when it was first released is to go through with this update to DOWNGRADE my console by taking


The Heilophora larvae in question were collected in temporary water pools in Cuba and documented only once. No other studies on the development of *C*. *hislopi*\[[@B62],[@B67]\] have ever described a free-swimming Heilophora larva - on the contrary, they have all reported hatchlings from resting eggs which emerged in possession of the adult morphology. It therefore appears possible that the authors confused the larva in question with a spinicaudatan larva resembling *Eulimnadia braueriana*. *E*. *braueriana* larvae correspond almost exactly in shape to the schematic drawing of the supposed Heilophora larva presented by Botnariuc and Viña Bayés \[[@B20]\]. In addition, both the Heilophora larva in question and those of *E*. *braueriana* exhibit a single median posteriorly directed labral spine (*E*. *braueriana* see Figure nine a and ten A in \[[@B66]\])pages.
Many companies offer various subscription services accessible via the Internet. For example, many people now do their banking, stock trading, shopping, and so forth from the comfort of their own homes via Internet access. Typically, a user, through subscription, has access to personalized and secure WEB pages for such functions. By typing in a user name and a password or other personal identification code, a user may obtain information, initiate transactions, buy stock, and accomplish a myriad of other tasks.
One problem that is encountered by an individual who has several or many such subscriptions to Internet-brokered services is that there are invariably many passwords and/or log-in codes to be used. Often a same password or code cannot be used for every service, as the password or code may


organized into larger IFT trains as they enter the flagellum ([@bib9]; [@bib25]; [@bib42]). In most species, the IFT trains are transported anterogradely from the base to the tip of a flagellum by heterotrimeric kinesin-II ([@bib22]), but some species also use a second homodimeric kinesin to build more specialized sensory cilia ([@bib58]). Once the trains reach the tip, they are reorganized and transported retrogradely to the ciliary base by dynein-1b ([@bib39]; [@bib43]; [@bib57]). Along the length of a cilium, the activities of kinesin and dynein motors are reciprocally coordinated, such that only one type of a motor is active at a time ([@bib56]). As a result, trains move between the tip and base of the cilium without significant pauses or back-and-forth motion ([@bib12]; [@bib13]) and switch directions at the(**c--e**) Kymographs of one (**c**), two (**d**) and three (**e**) fluorescent anterograde trains entering the flagellum. Anterograde trains pause at the flagellar tip and split into multiple retrograde trains that move back to the base. Arrival of fluorescent anterograde trains and departure of retrograde trains at the tip are shown with red and yellow stars, respectively. Arrows represent repetitive bleaching events near the base of the flagellum. (**f**) (Left) The number of fluorescent retrograde trains was quantified as a function of one, two or three fluorescent anterograde trains entering the flagellum after photobleaching. (Right) The average number of retrograde trains increased sub-proportionally with the number of fluorescent anterograde trains entering the flagellum. N = 97, 60, 42 train events from top to bottom, in 160 cells, from 13 independent experiments.


flagella. KAP-GFP and D1bLIC-crCherry arrive at the tip on the same train. In this example, KAP diffuses away from the tip before the departure of D1bLIC trains (right). Red and yellow stars indicate arrival to and departure from the flagellar tip, respectively. (**c**) A model for the turnover of IFT trains and motors at the flagellar tip. Kinesin-II motors transport individual anterograde IFT trains to the flagellar tip. Dynein-1b is carried with anterograde trains as an inactive passenger. At the tip, IFT complexes detach from microtubules, disassemble, and mix with the tip protein pool to assemble new trains. These trains are transported retrogradely by dynein-1b. Kinesin-II detaches from IFT trains at the flagellar tip and diffuses back to the base by diffusion either as a cluster (blue dashedcircle) or individually.](elife-28606-fig4){#fig4}

###### Dual color imaging of KAP-GFP and D1bLIC-crCherry.

The movements of KAP-GFP and D1bLIC-crCherry are simultaneously tracked in a surface-adhered *d1blic::D1bLIC-crCherry KAP-GFP* cell. KAP and D1bLIC co-localize in the anterograde direction. D1bLIC displays retrograde tracks while retrograde transport of KAP is rarely seen. KAP-GFP channel is on the left and D1bLIC-crCherry channel is on the right. The movie was recorded at 8.3 frames s^−1^ and is played in real time. This video corresponds to [Figure 4a](#fig4){ref-type="fig"}.

10.7554/eLife.28606.022

To determine which motor first departs from the tip after the arrival of an anterograde train, we performed two-color Photogate experiments to simultaneously track KAP-GFP and D1bLIC-crCherry from individual anterograde trains ([Figure 4b](#fig4){ref-type="fig"}). Out of 21 cells, KAP began diffusive motion before the retrograde movement of D1bLIC in 10 cells ([Figure 4b](#fig4){ref-type="fig"}),


flagella from 70 cells over two independent experiments. For IFT20-GFP, N = 103 flagella from 56 cells over two independent experiments. (**d**) Integrated KAP-GFP fluorescence at the basal body (left), in the flagellum (middle), and in both regions (right) in control cells was compared to cells treated with 50 mM Li^+^, and cells that regrow their flagella after cycloheximide treatment. R represents Pearson's correlation coefficient. Each dot represents a single flagellum. For control cells, N = 66 flagella from 33 cells. For lithium-treated cells, N = 74 flagella from 37 cells. For cycloheximide-treated cells, N = 40 flagella from 20 cells. (**e**) A model for flagellar length control. When the flagellum is short, IFT trains contain more kinesin-II from the large basal body pool. As flagella elongate, the number of kinesin-II per IFT train decreases becausethe cell body by dynein-1b and the amount of these components at the flagellar base remains nearly constant as the flagella elongate. Therefore, the abundance of IFT components and dynein-1b at the flagellar base is not limiting to maintain the length, consistent with previous observations that a small amount of IFT complexes and dynein-1b is sufficient to maintain fully grown flagella ([@bib49]; [@bib63]).

Diffusion is also proposed to play a role in setting the length of bacterial flagella ([@bib50]), long polymers made from a single protein flagellin. Similar to the flagellar length control model originally proposed for *Chlamydomonas* ([@bib27]), flagellins are injected into the channel of the filament and they diffuse to reach the assembly site at the filament tip, generating a concentration gradient decreasing towards the tip. As


that the lower amount of kinesin-II negatively affects the assembly rate. However, a more recent study showed that *fla10^ts^* flagella contain wild-type levels of kinesin-II at permissive temperatures ([@bib63]). Given these apparent discrepancies, more quantitative approaches will be required to address whether the amount of kinesin-II correlates with flagellar length.

According to the balance-point model, flagella that contain lower amounts of kinesin-II can still maintain nearly full-length if they also have a lower disassembly rate. The studies that reported a reduction in kinesin-II expression in *fla10^ts^* and *fla3* cells also noted significantly reduced anterograde IFT frequency and IFT particle subunits in flagella ([@bib35]; [@bib40]). This could negatively affect the disassembly rate because IFT is required for efficiently removing certain axonemal precursors ([@bib46]) and resorbing the flagellum prior to mitosis.ms frame time. The effective pixel size was 160 nm.

PhotoGate assays {#s4-6}
----------------

The PhotoGate system was assembled as previously described ([@bib2]). Briefly, a 488 nm laser beam was split into two paths using a half-wave plate and a polarizer beamsplitter cube. The first path was used for objective-type TIR imaging. The second path was focused (2 MW cm^−2^) to the image plane and steered with a fast piezo-driven mirror (S-330.8SL, Physik Instrumente, Karlsruhe, Germany). The piezo-driven mirror was mounted at a position conjugate to the back-focal plane of the objective to ensure that the tilting of the mirror resulted in pure translation of the focused beam in the image plane. The mirror provided a usable travel range of 30 µm x 30 µm area at the image plane. The mirror's angle


adjusted such that less than 1% of anterograde IFT trains moved faster than the cutoff speed (3.0 µm s^−1^). The trajectories of these trains can be distinguished from each other as they move at different speeds along the flagellum. The locations of flagellar tips were determined by brightfield imaging (data not shown). In two-color photogate experiments, the focused 488 nm laser beam was used to bleach both GFP and crCherry, and 488 and 561 beams were used in a time-sharing mode for TIR excitation.

FRAP assays {#s4-7}
-----------

FRAP assays on the *fla3::*KAP-GFP strain were performed by photobleaching the center part of the flagellum (5 µm in length) for 200 ms at 25 kW cm^−2^ in the epifluorescence mode. The recovery of fluorescence signal in the bleached area was simultaneously monitored by imaging with a 100the section \"Kinesin-2 carries dynein-2 as an inactive passenger during anterograde IFT\" belong in the Discussion. In particular, the last of these paragraphs which discusses the differences between Chlamy, worm, and mammalian IFT processes, concerns one of the most important findings of the paper and needs to be prominently and thoroughly discussed.

10.7554/eLife.28606.033

Author response

> Essential revisions:
>
> 1\) The results testing various agents to see if they affect the tip turnaround dynamics are interesting but raise many questions. For ciliobrevin, there is an increase in the return time of IFT27 and KAP. The authors should explain better what effect ciliobrevin has on anterograde and retrograde IFT and the number of these events.

We previously published the effect of ciliobrevin D in IFT movement in Shih et al. 2013 *eLife*. In that


to Discussion.

> In particular, the last of these paragraphs which discusses the differences between Chlamy, worm, and mammalian IFT processes, concerns one of the most important findings of the paper and needs to be prominently and thoroughly discussed.

We expanded this section to clearly identify differences between IFT and ciliary length control in *Chlamydomonas* in Discussion.

[^1]: These authors contributed equally to this work.
also in the context of desktop or large data processing systems not intended to be user-portable.
In the larger data processing system context, a reduction in power consumption may be necessary to achieve eligibility for certain environmental impact standards or labels such as the “Energy Star” rating system established by the United States Department of Energy and the Environmental Protection Agency or merely to reduce the cost of operating a data processing system associated with system power. The issue of power management is even more critical in larger scale data processing systems such as supercomputers, parallel processing data processing systems (e.g., massively parallel processing systems), server data processing system “farms”, and rack servers.
A rack server is a data processing system including a storage rack element into which one or


2016-01-29 21:27 7.dmp
-rw-rw-rw-  1 HP 0 96698 2016-01-29 21:27 8.dmp
-rw-rw-rw-  1 HP 0 96698 2016-01-29 21:27 9.dmp
-rw-rw-rw-  1 HP 0 96698 2016-01-29 21:27 CRASH.DMP

running cdb with no symbol path to eliminate symbol loading and running a command on each of the file and grepping the result
:\>for /F %I In ('dir /b') Do cdb -sins -z %I -c ".exr -1;q" | grep -i att

result as follows
:\>cdb -sins -z 1.dmp -c ".exr -1;q"   | grep -i att
Attempt to read from address 0a29f6ac

:\>cdb -sins -z 10.dmp -c ".exr -1;q"   | grep -i att
Attempt to read from address 0a29f6ac

:\>cdb -sins -z 2.dmp -c ".exr -1;q"   | grep -i att
Attempt to read from address 0a29f6ac

:\>cdb -sins -z 3.dmp -c ".exr -1;q"  a Public Accountant in Rapid City, South Dakota) could run this business and take it over. They felt very confident in me that I could do that and they could retire.

It was a challenge and something we were interested in doing, and getting into our own business. A lot of times you don't think of going to an Indian reservation and running a business, but it was a great opportunity. We thought it would be nice for the family and children.

We were there until the militant Indian thugs came and took it over and burned it to the ground.

I had a meeting today with Native Sun News and we’re going to be on TV tonight at 5 and 10 o’clock.

I was told you and your family were run


is a well known practice and not one that is overcome by misdirecting the question with untruthful 'facts.' Why the story? Given proper education and guidance, any man can change his circumstances if there is a level playing field/opportunity. To put it in other terms: if there were away to actually make money based on available resources, things would be different. The reservation system, give the most inhospitable land and taking away means to take care of themselves and allowing those with the trust to govern to rob and abuse, doesn't give us much of a chance.

yeah...the Ogala Sioux had SOOOOO much money.....to afford to buy the land of their ancestors.....sigh.....why can't we get together as the People (no matter what Nation) and pledge $20 per person, toMeteorological Data Sharing Service System (<http://cdc.cma.gov.cn/>). The meteorological variables included daily average temperature (AT), daily minimum temperature (MiT), daily maximum temperature (MaT), daily average relative humidity (ARH), daily minimum relative humidity (MiRH), daily average air pressure (AAP), daily minimum air pressure (MiAP), daily maximum air pressure (MaAP), daily average wind velocity (AWV), daily maximum wind velocity (MaWV), daily extreme wind velocity (EWV), daily precipitation (DP), daily average vapor pressure (AVP), and daily sunshine duration (SD). We used meteorological data from the meteorological station in the landing city or the nearest station if there was no station in the city of landfall. Based on the classification of precipitation by the China Meteorological Administration and data during the studied tropical cyclones, daily precipitation was categorized as grade 0 (less than


10 mm), grade 1 (10--24.9 mm), grade 2 (25--49.9 mm), grade 3 (50--99.9 mm) and grade 4 (more than 100 mm) \[[@B22-ijerph-12-01054]\].

2.4. Epidemiological Method and Statistical Analysis
----------------------------------------------------

In this study, a unidirectional 1:1 case-crossover design combined with conditional logistic regression models were used to analyze the exposure odds for the case period compared with the control period. Case-crossover design is an effective method to measure the influence of transient exposure to acute diseases \[[@B23-ijerph-12-01054]\]. As in a matched case-control study, this design compares each case's exposure before a case-defining event with that case's exposure during other period. Because this design is similar to a crossover study, in which each case serves as their own control, characteristics that did not change between case and control periods, such as age, sex,tropical cyclone precipitation at grade 4 was larger than that of grade 3.

![ORs and 95% CIs of tropical cyclone precipitation on the risk of bacillary dysentery on different lagged days. OR: odds ratio; CI: confidence interval; A: impact of grade 1 (10--24.9 mm) precipitation on bacillary dysentery; B: impact of grade 2 (25--49.9 mm) precipitation on bacillary dysentery; C: impact of grade 3 (50--99.9 mm) precipitation on bacillary dysentery; D: impact of grade 4 (more than 100 mm) precipitation on bacillary dysentery.](ijerph-12-01054-g004){#ijerph-12-01054-f004}

![ORs and 95% CIs of tropical cyclone precipitation as the risk for other infectious diarrhea on different lagged days. OR: odds ratio; CI: confidence interval; A: impact of grade 1 (10--24.9 mm) precipitation on other infectious diarrhea; B: impact of grade 2 (25--49.9 mm) precipitation on other


found that ORs of precipitation between 10--25 mm were significantly lower than one, which indicated that tropical cyclone precipitation between 10--25 mm was probably beneficial to human health. The mechanism of this protective effect needs further study. One possible reason is that tropical cyclones are characterized by strong wind and precipitation; thus, tropical cyclones with relatively little precipitation and strong wind result in dry weather, which may be adverse to human health. In addition, a very short or no lagged effect was observed for tropical cyclone precipitation. These results suggest that more attention should be focused on prevention and control of infectious diarrhea diseases when precipitation reaches 25 mm or above following tropical cyclones. Previous studies documented that heavy precipitation was associated with gastrointestinal illness. Positive association betweenextreme precipitation and gastrointestinal illness-related hospital admission also was reported from 2004 to 2007 in Chennai, India \[[@B35-ijerph-12-01054]\]. Our findings indicate that risks of bacillary dysentery increased significantly after exposure to heavy rain (25.0--49.9 mm), torrential rain (50--99.9 mm), and extreme torrential rain (≥100 mm) caused by tropical cyclones, which is similar to the Taiwanese study, which found that risks of bacillary dysentery increased nearly twofold after exposure to torrential rain and seven times after exposure to extreme torrential rain \[[@B27-ijerph-12-01054]\]. Also in northeast China, a positive correlation between precipitation and bacillary dysentery was noted \[[@B36-ijerph-12-01054]\].

However, the association between precipitation and diarrhea was far from clear. In a study in Wuhan, China, researchers obtained results confirming an inverse association between precipitation and infectious diarrhea \[[@B32-ijerph-12-01054]\]. Another study in


Ecuador found that heavy precipitation events were associated with increased diarrheal disease incidence following dry periods and decreased diarrhea incidence following wet periods \[[@B37-ijerph-12-01054]\]. Another two studies did not detect any significant effects of precipitation on infectious diarrhea in cities at the northern and southern parts of China \[[@B38-ijerph-12-01054],[@B39-ijerph-12-01054]\]. This observed discrepancy may have resulted from socioeconomic factors such as individual perceptions and behaviors, socio-economic status, and access to health services. For instance, citizens' low awareness of health issues and unhealthy drinking habits may make them more susceptible to infectious diarrhea. Economic status determines the level of health service and the drinking water sanitation to some extent, and thus, may influence the risk of suffering infectious diarrhea. In addition, different intensities of precipitation in different studies might beanother reason for varying results. For example, the Taiwanese study investigated the impact of extreme torrential precipitation (\>350 mm/day) on bacillary dysentery \[[@B27-ijerph-12-01054]\], while the impact of a quite lower daily precipitation (3.1 mm) was studied in Wuhan \[[@B32-ijerph-12-01054]\].

Due to limited number of tropical cyclone events in Zhejiang province during 2005--2011, the impacts of other categories of tropical cyclones, such as tropical depression and severe tropical storm, on infectious diarrhea with longer lags could not be assessed in our study. In addition, there might be other factors that could influence transmission of infectious diarrhea.

Irrespective of these limitations, there are some advantages of this study. First, the case-crossover study design, similar to a matched case--control study, is advantageous in controlling confounders. Confounders, such as geographical characteristics, behaviors and economic


health impacts from tropical cyclones.

The study was supported by the National Basic Research Program of China (973 Program) (Grant No. 2012CB955500-955502). We appreciate National Notifiable Disease Surveillance System as well as China Meteorological Data Sharing Service System for providing data for our research.

Zhengyi Deng, Huanmiao Xun and Wei Ma conceived and designed the study; Zhengyi Deng, Huanmiao Xun, Songwang Wang and Qing Guo performed the study; Zhengyi Deng, Huanmiao Xun, Maigeng Zhou and Baofa Jiang analyzed the data; Wei Wang, Xin Wang, Ruihua Kang and Gifty Marley contributed reagents/materials/analysis tools; Zhengyi Deng and Huanmiao Xun wrote the paper.

The authors declare no conflict of interest. The founding sponsors had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing ofA gas and vapor generation system with programmed automatic cyclic output.
This paper describes a gas and vapor generation system that can be programmed to produce contaminant concentrations that are variable with time and that are repeatable. The system utilizes an electromechanical programmer designed to vary a potentiometer in accordance with variations in a program curve manually etched in the surface of a special program card. The output of this programmer is interfaced with a linear mass flow controller which will control either the contaminant stream or the dilution air stream to achieve the desired range of contaminant concentrations. The results of some experiments with carbon monoxide and toluene show repeatability of one to three percent for periodically repeated cycles, and demonstrate the flexibility of the system.


cost.
A conventional method of managing a network resource has a one-level logic structure. Such a structure has a number of constraints for each action requested. For instance, if user A wants to access a network X, the network X would look up user A""s profile to see whether user A is authorized for such access. In addition to the authorization information, user A""s profile would include other information about his privileges with respect to the network resources.
Conventional management tools use a centralized management console for configuring, monitoring, and controlling the behavior of various network devices in the network. Typically, a single logical console is responsible for a given control domain (e.g., a Windows NTO domain or an administrative domain for routing protocols), and the control domains themselves areusing a policy tree that includes a plurality of levels (e.g., two levels, five levels, etc.). The policy tree may be generated/updated by the network and/or an outside system. When the network receives a request for providing an action to a particular source, the network determines if the action is available as a function of at least one level of the plurality of levels. If the action is available, then the network determines if the particular source is authorized to be provided with the action as a function of at least one rule of at least one further level of the plurality of levels. If the particular source is authorized, then the network provides the action to the particular source.
The plurality of levels of the policy may include


"Well, I know one thing's for sure." "There's definitely someone bitchier than me." "Oh, you better not mean me." "Oh, I so mean you!" " Oh." " Nice burn." " Top shelf." " Thanks." "Well, now, that's strange." "Midge's car's right there." "Bob said she wasn't home." "In fact, I haven't seen her for days." "Maybe she went to the store and forgot where she lived." "Oh, that's... that's wrong." "Okay, Fez, this'll cheer you up." "With these you can look into the Pinciotti's house and frequently enjoy... a naked Midge, up close and personal." "That's exactly how I like my naked Midges." "Oh, but, Fez, be warned." "If Bob approaches a naked Midge, look away." "Oh, for the love of God, look away." "Okay, let's practice." "Nakedas the trailer travels, thereby scooping a soil sample. As the cam rolls forward, the digger foot is released and a spring biases the digger foot upward, where it strikes a bumper block and deposits the soil sample into a collection container. Like the Alexander device, the Mabry et al. device automatically samples soil at regular intervals, since its sampling periodicity is driven by the distance traveled by the cam-equipped tractor wheel.
U.S. Pat. No. 5,741,983 to Skotnikov et al. teaches a third trailer-mounted automatic soil sampling device. In this case, an odometer is used to monitor the distance of travel of the trailer, which drives the sampling period of the device. The device utilizes a shaft-drive and linkage arrangement to control the period of the sampling action based


tube to push backward against soil that is rearward of the tube at its distal end, and push forward against soil that is forward of the tube at its proximal end. While this may be a workable solution in very loose, highly compressible soil, this will likely lead to bending, excessive wear, or other damage to the tube in more firmly packed soil, or soil that may contain rocks or other hard obstacles.
Another solution to the problem of vehicle motion while the tube is inserted in the ground is a complex linkage arrangement that allows the structure immediately supporting the sampling tube to “follow” the tube during the portion of the sampling cycle when the tube is inserted into the ground. While this arrangement may avoid the problemswith bilateral temporo-parietal, retrosplenial and left frontal cortices. During recognition, both patient and controls activated right parahippocampal, right superior parietal and right frontal cortices. Notably, control subjects, but not O.I., also activated at encoding the precuneus and at recognition the retrosplenial cortex. This allows the conclusion that these two areas while involved may not be necessary for topographical memory. Interestingly, the patient also activated regions that were not evident in control subjects both during encoding and recognition. These additional areas of activation may be necessary in a compensatory role. Overall, these data represent the first reported assessment of the functional integrity of degenerating brain tissue and its contribution to preserved topographical memory. The combination of the neuropsychological and neuroimaging approaches may provide insights into the functional-anatomy of memory


German submarine U-555

German submarine U-555 was a Type VIIC U-boat of Nazi Germany's Kriegsmarine during World War II. The submarine was laid down on 2 January 1940 at the Blohm & Voss yard in Hamburg as yard number 531, launched on 7 December 1940, and commissioned on 30 January 1941 under the command of Kapitänleutnant Hans-Joachim Horrer.

Design
German Type VIIC submarines were preceded by the shorter Type VIIB submarines. U-555 had a displacement of  when at the surface and  while submerged. She had a total length of , a pressure hull length of , a beam of , a height of , and a draught of . The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of  for usefirst
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();';
ERROR = !'multiplex' should be used
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.multiplex();';
ERROR = !'deadcode' should be used at least once
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.multiplex();optimizer.deadcode();';
ERROR = !'garbageCollector' should be used as the last one
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.deadcode();optimizer.multiplex();';
ERROR = !'garbageCollector' should be used as the last one
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.deadcode();optimizer.inline();optimizer.multiplex();optimizer.garbageCollector();';
ERROR = !'inline' should be the first
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.deadcode();optimizer.garbageCollector();optimizer.multiplex();';
ERROR = !'remap' should be used
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.multiplex();optimizer.deadcode();optimizer.garbageCollector();';
ERROR = !'remap' should be used
CODE  = 42000
MAPI  = (monetdb) /var/tmp/mtest-30274/.s.monetdb.37685
QUERY = set optimizer='optimizer.inline();optimizer.deadcode();optimizer.multiplex();optimizer.garbageCollector();';
ERROR


is also known as the *Condensation method*. For the right hand side this method is however not applicable and the proof relies on the *method of identification of factors*. Secondly the determinant by Ciucu et al. is a weighted enumeration of cyclically symmetric lozenge tilings of hexagons with a triangular hole, these are a “one parameter generalisations” of DPPs, where $q$ corresponds to the weight and $x$ is the side length of the hole. Very recently Fischer proved in [@Fischer1804.08681] that this determinant also enumerates alternating sign trapezoids, which are one parameter generalisations of ASTs. Hence the determinant $d_{n,k}(x,q)$ suggests a one parameter refinement for ASMs and might be of help in finding one.\
The paper is structured in the following way. In Section \[sec: herleitung\] we follow thein a variable $x$, as suggested in [@Fischer18], and further a parameter $k \in {\mathbb{Z}}$. The determinant of our interest is then $d_{n,k}(x,q):=\det\left( D_{n,k}(x,q) \right)$, where $D_{n,k}(x,q)$ is defined by $$D_{n,k}(x,q):=\left(\binom{x+i+j-2}{j-1}\frac{1-(-q)^{j-i+k}}{1+q}\right)_{1 \leq i,j \leq n}.$$ The evaluation of this determinant will generally follow two steps. The first step is to guess a formula for $d_{n,k}(x,q)$ using a computer algebra system. The second step is to use induction and the Desnanot-Jacobi Theorem, which is sometimes also called *condensation method*.

\[thm: Condensation method\] Let $n$ be a positive integer, $A$ an $n \times n$ matrix and denote by $A_{j_1,\cdots, j_k}^{i_1,\cdots, i_k}$ the submatrix of $A$ in which the $i_1,\cdots, i_k$-th rows and $j_1,\cdots, j_k$-th columns are omitted. Then holds $$\label{eq: condensation}
 \det A \det A_{1,n}^{1,n} = \det A_1^1 \det A_n^n -\det


Introduction
============

Decision making requires a trade-off between gains and losses ([@B37]). Behavioral economists have argued that good decision making is to maximize our expected utility over the long term ([@B69]). Researchers have developed laboratory tasks to assess decision-making abilities. The Iowa Gambling Task (IGT) is probably the most commonly used experimental paradigm in clinical settings to assess the ability to sacrifice immediate interests in favor of long-term benefits ([@B7]). On this task, participants choose one deck from four and over time normal participants gradually learn to choose from the two advantageous decks and avoid the two disadvantageous decks. The other commonly used task, especially among behavioral economists, is the Inter-Temporal Choice task (ITC), on which participants choose between a small immediate reward and a larger later one. In thisrelationship between DLPFC and decision making still needs to be established. In a pioneering study, [@B19] applied low-frequency repetitive transcranial magnetic stimulation (rTMS) to the left DLPFC and found that disrupting that region led to a preference for more immediate but smaller rewards over delayed but larger rewards. To extend this line of research, the present study used the High-definition Transcranial Direct Current Stimulation (HD-tDCS) to investigate the role of left and right DLPFC in decision making as assessed by the IGT and intertemporal choice task. The tDCS is a proven method of delivering a non-invasive brain stimulation ([@B21]). In three experiments, participants of this study completed the IGT, the ITC task, and the Barratt Impulsivity Scale (BIS) after either real or sham stimulation over the left or


detail of this task has been extensively described in previous studies ([@B7], [@B8]). Briefly, four decks of cards labeled A, B, C, and D were displayed on the computer screen. Participants were asked to select one card at a time from one of the four decks. After each selection, a message was displayed on the screen indicating the payoff of that trial. Each card selection could bring an immediate reward (the immediate reward was higher in decks A and B than in decks C and D). As the game progressed, there were also unpredictable losses associated with each deck. The total losses were on average higher in decks A and B relative to decks C and D, thus creating a conflict in each choice, i.e., decks A andfrom [@B34] and [@B42], [@B43]). The adaptive procedure allowed for a precise estimation of *k*. The delay was always 120 days, and the magnitude of the future reward was held constant. The initial amount of the immediate reward was generated by computing what would be an amount of equal value to the future reward based on the *k* parameter derived from the questionnaire. For each trial, if the participant chose the immediate reward, the *k* parameter was adjusted upward by a quarter step on a *log~10~* scale, and consequently, the value of the immediate reward on the next trial was lower. Conversely, if the participant chose the future reward, then the *k* parameter was adjusted downward by a quarter step on a *log~10~* scale, resulting in a larger


± 4.52), and there was no difference in dBIC between the two conditions \[*t*(19) = 0.16, *p* = 0.56\]. Three parameters estimated from rEV model were compared between the two conditions using paired-samples *t-*test. Results showed a significant condition difference in the recency parameter \[*t*(19) = 2.57, *p* = 0.02, Cohen's *d* = 1.28\] (**Figure [2](#F2){ref-type="fig"}**), but no differences were found in the other two parameters (both *t*s \< 0.23, *p*s \> 0.80). The HD-tDCS condition (0.11 ± 0.03) had a smaller recency parameter than the sham condition (0.39 ± 0.09), suggesting that after HD-tDCS, subjects relied more on the past information and learned faster as compared to after the sham stimulation. Because the recency parameter had a skewed distribution, we re-analyzed the data after a natural logsubsidiary.

The left has expertly crafted the use of the language to suit their ideological needs with flowery sounding terms such as “sustainability” and its use in this piece of legislation is no coincidence. Legislation of this type is part of an agenda, on behalf of the believers in big government solutions to small-community problems, to disarm communities and their residents of the ability to manage their own households and communities in favor of ceding this authority to a class of pseudo-intellectual politicos who, according to their thinking, understand how to utilize and care for your land better than you do. This rather dangerous proposition opens a Pandora’s Box of government-caused inequity, enforced under the penalty of law, and enacted under the guise of environmental “management” and “sustainability”.

Enforcing legislation


Chernobyl, the Aral Sea, and the Three Gorges Dam are but a few of the legions of environmental disasters resulting from government “planners” and their perverse agendas.

You may write this off as a leap too far but when the trend line for ceding personal economic, healthcare, public-safety, educational and now private property liberties all trend in the direction of you losing and government gaining, I think you’ll better understand my concerns. After all, liberty is a zero-sum game; it cannot belong to you and your government at the same time.

(Dan Bongino is a former Secret Service agent and current entrepreneur who ran for US Senate from Maryland in 2012)Q:

How to remove elements from a list in a certain pattern?

I have been trying to work on this certain pattern for quite some time but I am unable to come up with a solution. For example I have list like: n = ['M', 'M', 'B', 'B'].
Now, I know how to remove the elements from a list that have odd indexes or even indexes like del n[1::2] for odd indexes and del n[0::2] for even indexes.
However, I am looking to remove in a pattern like this: 0, [1], 2, [3], [5], [8]..... so on and so forth. The brackets are for the elements in those certain indexes to be removed.
The n list is just an example, I have much larger lists with more elements. So far, all


  *  is 0, the limit is 4GBytes, it uses 4KByte granularity,
    *  uses 32-bit opcodes, and is a Code Segment descriptor.
    *  Please check the table above in the tutorial in order
    *  to see exactly what each value means */
    gdt_set_gate(1, 0, 0xFFFFFFFF, 0x9A, 0xCF);

    /* The third entry is our Data Segment. It's EXACTLY the
    *  same as our code segment, but the descriptor type in
    *  this entry's access byte says it's a Data Segment */
    gdt_set_gate(2, 0, 0xFFFFFFFF, 0x92, 0xCF);

    /* Flush out the old GDT and install thecascade can have devastating effects on the safety profile of a drug.

2. Material and Methods {#sec2}
=======================

2.1. Materials {#sec2.1}
--------------

Papain 99% purity was obtained from Sigma Chemical Company (St. Louis, USA). Fluoxetine (an antidepressant drug) was purchased from Ranbaxy (India). The solutions were prepared in 50 mM phosphate buffer of pH 7.4. Salts of different metals, phosphate were purchased from Merck (India). The protein concentration was determined spectrophotometrically. All other materials were of analytical reagent grade and double distilled water was used throughout ([Figure 2](#fig2){ref-type="fig"}).

2.2. Apparatus {#sec2.2}
--------------

The absorbance spectra were recorded on a double beam Shimadzu UV-Vis spectrophotometer UV-1700 using a cuvette of 1 cm path length. Fluorescence measurements were performed on a spectrofluorometer Model RF-5301PC (Shimadzu, Japan) equipped with a 150 W Xenon lamp and a slit width of 10 nm. A 1.00 cm quartz


of the papain family of cysteine proteinases \[[@B29]\].

E-64 isolated from cultures of*Aspergillus japonicus* is a very strong and irreversible inhibitor of cysteine proteases \[[@B30], [@B31]\].

Cystatins the crucial inhibitors for proper brain functioning have been reported from several mammalian sources and an imbalance of proteinases (cathepsins) with their endogenous inhibitor cystatins is closely associated with senile plaque, cerebrovascular amyloid deposits, and neurofibrillary tangles in Alzheimer\'s disease. It has also been reported that cystatin C is present in high concentration in CNS and is suggested to play an important role in diseases of the brain \[[@B32]\]. A proteinase inhibitor is of physiological importance because inhibition is achieved at physiological concentration of the inhibitor in a sufficiently short time with negligible dissociation of the complex. Endogenous thiol proteinase inhibitors the cystatinsit made, gives an average cost per meal of… bodhrán-roll, please…

€1.50 per meal. That means my total cost for eating 3 nutritionally-balanced meals a day for a week is €31.50. Pretty cool, huh??!

So if you’re interested in organizing your food in a cheaper, and/or faster way,

I buy all the ingredients on my batch-cooking shopping list, except for tamari and occasionally tofu, in Aldi . It just happens to be the closest budget supermarket. Based on a quick gawk, Lidl is probably just as good.

Ask at the supermarket what days and times they get their deliveries of veg, plus what time they usually get the veg on display, and schedule your food-shopping accordingly. I find frozen spinach sells out really quick in Aldi… us Galwegians are more health-conscious than


bug in Android 4.0.* where (2) destroys native `audio`
 *    and `video` controls.
 * 2. Correct inability to style clickable `input` types in iOS.
 * 3. Improve usability and consistency of cursor style between image-type
 *    `input` and others.
 * 4. Remove inner spacing in IE 7 without affecting normal text inputs.
 *    Known issue: inner spacing remains in IE 6.
 */

button,
html input[type="button"], /* 1 */
input[type="reset"],
input[type="submit"] {
    -webkit-appearance: button; /* 2 */
    cursor: pointer; /* 3 */
    *overflow: visible;  /* 4 */
}

/**
 * Re-set default cursor for disabled elements.
 */

button[disabled],
html input[disabled] {
    cursor: default;
}

/**
 * 1. Address box sizing set to content-box in IE 8/9.
 *button in Safari 5 and Chrome
 * on OS X.
 */

input[type="search"]::-webkit-search-cancel-button,
input[type="search"]::-webkit-search-decoration {
    -webkit-appearance: none;
}

/**
 * Remove inner padding and border in Firefox 3+.
 */

button::-moz-focus-inner,
input::-moz-focus-inner {
    border: 0;
    padding: 0;
}

/**
 * 1. Remove default vertical scrollbar in IE 6/7/8/9.
 * 2. Improve readability and alignment in all browsers.
 */

textarea {
    overflow: auto; /* 1 */
    vertical-align: top; /* 2 */
}

/* ==========================================================================
   Tables
   ========================================================================== */

/**
 * Remove most spacing between table cells.
 */

table {
    border-collapse: collapse;
    border-spacing: 0;
}


core an ongoing research program to study auditory development in CI infants. Local coursework and training experiences in the fields of auditory development, speech and language development, and electrophysiology will enable the PI to continue to build the skill set necessary to translate basic psychoacoustic research findings into clinically feasible measures. This career development and research plan, conducted within an extremely supportive and nurturing academic environment will set the candidate up to succeed as a sustainably funded investigator overseeing this clinically relevant program of research.Selecting an Artist

In order to contribute a new entry you must first select an artist who fulfills the following criteria:

She is a woman of color.

She has completed at least one full-length publication (book) that is either fiction, poetry, or literary nonfiction, or is an artist whose visual or sonic works (films, exhibits, music, etc. ) indicate a significant career. Exceptions to this criterion are made for some artists at the discretion of the VG Editorial Board.

No one has yet claimed the option to create an artist page for this artist for the VG project. In other words, any artists on our Artist List who do not already have an Artist Page. In addition, if you know of an artist who does not appear on our list but who


thousands of established writers in the English language who lived into the twentieth century.

Book Review Index (Quarto Z1035 .A1 B6). This work will tell you where an artist's books have been reviewed so you can go look the reviews up.

This is not an exhaustive list of resources but should provide a number of places to start. If you come across what you consider to be a particularly useful general resource, please send us a note at voices@umn.edu, and we'll add it to this list.

All submissions and bibliographic citations should conform to current MLA style, according to the MLA Handbook for Writers of Research Papers. Titles of works should be italicized, rather than underlined. VG reserves the right to reject submitted pages if the content is inaccurate or doesnot meet Editorial Board standards.

Obtaining Permissions

After selecting images, audio, or video you would like to include on your artist page, determine whether these are copyrighted. A good deal of visual and audio material is in the public domain: one source for uncopyrighted material is the Library of Congress. However, if the image or audio file is copyrighted, efforts to obtain written permissions from the copyright holder — often the photographer, writer, artist, her agent, or the publisher of the source — must be made in order to republish the material on VG. Along with completing your submission, you must write to the copyright holder to obtain permissions to republish any images, audio files, and videos you would like to include on your artist page. Permissions obtained from other


billing and collecting. In most cases, attorneys who start their own firms have to bill like crazy, and they don't ever really get a chance to run the business because they are too busy bringing in money. If you are a gifted rainmaker, you can possible bring in enough to feed associates who will make money for you, but this usually doesn't happen until you have done a ton of legal work. IN short, you should open a law firm if you love doing legal work, and it's a necessary side benefit that you love sales and management.

Personal and Professional Growth: Well, okay. But the law eats professional growth. Lawyers don't generally cross industries because there are too many conflicts. It can happen, but it will likely replaceMusic can be an important part of an exercise or other physical activity routine for many people. For example, runners, weight lifters, participants in aerobic exercises, users of cardiovascular exercise machines (e.g. stair steppers, stationary bicycles, elliptical motion machines, and the like), etc. frequently listen to music while participating in such activities. Music can help alleviate boredom, and a particularly motivational or inspirational song or group of songs can be helpful in maintaining focus and improving performance. However, while a user can assemble a group of songs (also referred to as a playlist or “mix”) using one or more sources such as a personal music collection, an online music streaming service, or the like, such playlists generally lack the ability to react to the specifics of the physical


jpaProperties.put("hibernate.dialect", "org.hibernate.dialect.MySQLDialect");
    //jpaProperties.put("hibernate.hbm2ddl.auto","create-drop");
    jpaProperties.put("hibernate.show_sql", false);
    jpaProperties.put("hibernate.format_sql", false);
    jpaProperties.put("hibernate.use_sql_comments", false);
    jpaProperties.put("hibnerate.connection.CharSet", "utf8");
    jpaProperties.put("hibernate.connect.characterEncoding", "utf8");
    jpaProperties.put("hibernate.connection.useUnicode", true);

    jpaProperties.put("jadira.usertype.autoRegisterUserTypes", true);

    factory.setJpaProperties(jpaProperties);
    factory.afterPropertiesSet();
    factory.setLoadTimeWeaver(new InstrumentationLoadTimeWeaver());
    return factory;
}

I switched on logging and I can see it is "skipping" my initialise file, which I'm not sure why. The schema hasn't been created.
l.util.logging.slf4j.Slf4jLog 40 debug - Scanning for classpath resources at 'db/migration' (Prefix: 'V', Suffix: '.sql')
16:35:08.272 DEBUG org.flywaydb.core.internal.util.logging.slf4j.Slf4jLog 40 debug - Scanning URL: file:/Users//Documents/Projects/MerchantX/target/java_ecommerce/WEB-INF/classes/db/migration/
16:35:08.273 DEBUG org.flywaydb.core.internal.util.logging.slf4j.Slf4jLog 40 debug - JBoss VFS v2 available: false
16:35:08.273 DEBUG org.flywaydb.core.internal.util.logging.slf4j.Slf4jLog 40 debug - Scanning starting at classpath root in filesystem: /Users//Documents/Projects/MerchantX/target/java_ecommerce/WEB-INF/classes/
16:35:08.273 DEBUG org.flywaydb.core.internal.util.logging.slf4j.Slf4jLogDiscover and support independent comic books with Emanata Comics for iOS and Android.

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Category Archives: Artists

With all that’s been happening around the office lately, we neglected to mention how much we enjoyed our time at APE 2012. It was great to meet so many of you in person. We would love to meet more of our users and artists. Which events would you like to see us at? We have a list of possibilities, but we would love to know which conventions are your favorites.

So, what’s been going on with us? We just updated to version 2.1.1! Get your update in the App Store for an even better reading experience on your iPhone / iPad Mini. We also added a new feature for our artists — adjustable preview for


voidin order that others may know.In the land of the nightthe ship of the sunis drawn by the grateful dead.-- Egyptian Book of the Dead

Very thought provoking. This is a wonderful connection to the term "grateful dead" and lyrically it could just as easily come out of some lost song that didn't make it on to the Aoxomoxoa album.

Finally, the band's musical story-scape itself finds a wonderful tie in when checking out that old Funk & Wagnalls Folklore dictionary entry which reads something like this:

GRATEFUL DEAD: The motif of a cycle of folk tales which begin with the hero coming upon a group of people ill-treating or refusing to bury the corpse of a man who had died without paying his debts. He gives his last penny, eitheror Billy why the band called themselves Warlocks, they might get a direct and somewhat accurate answer, but it wouldn't be fascinating.

I recall a story that Phil had found a 45 in a record store by another band called the Warlocks, which initiated a quest for a new name. During the 11.3.65 studio session they called themselves "The Emergency Crew" because they did not have any other name to use. The story Jerry tells of the dictionary falling open to "Grateful Dead" does feel like the most accurate telling, at least for the reality we now experience. Oh, and when they went back to find that record nobody saw it...

The bit about the Egyptian Book of the Dead (aka "Awakening Osiris") is likely fictional, as nobody has ever