materials with extremely poor conductivity. When the crystalline salts are immersed in physiological solutions they continue to exhibit their dielectric characteristics. Konikoff (U.S. Pat. No. 4,142,521) shows a bandage or surgical sponge material incorporating one or more electret elements, each electret providing a small electrostatic field to the area of the wound.
Spadaro (1974) and Becker (1976) reported electrically-generated silver ions, could can penetrate deeply in to the tissues, were noted to be effective even against antibiotic-resistant strains of bacteria, fungi, etc., inhibiting growth in vivo and in vitro at current densities as low as 10 μA/mm2 and silver ion concentrations as low as 0.5 mg/ml. U.S. Pat. No. 4,528,265 of Becker discloses processes and products that involve subjecting mammalian cells to the influence of electrically-generated silver ions. Anodictips on how to prepare foods, give history on unique varieties and answer common gardening questions. Remember, farmers are often very passionate about what they do, so be prepared for an earful! They have lots of knowledge to share.

Some questions to ask at a Farmers Market:

What are your growing practices?

How do you raise and feed your animals?

What do you do about pests and weeds?

How do you care for your soil? From where do you source seeds?

If your market allows carrying or reselling goods from another farm, ask the farmer if they grew everything in their booth and when it was harvested

Who are your role models or is there a farm after which you fashion your practices?

Questions for retail stores with meat or produce with a “local” label:

Who is


Europe is increasingly causing weather systems to stall and leading summer temperatures to soar.

The World Meteorological Organization said on Friday that 2019 was on track to be among the world's hottest years, and that 2015-2019 would then be the hottest five-year period on record.

It said the European heatwave was "absolutely consistent" with extremes linked to the impact of greenhouse gas emissions.proteins that are supported at RNA level was of 26.2 ([Table 4](#t4){ref-type="table"}). The AAR value for the set of 121 ES proteins that is specific of *T. solium* genome was of 28.9, while the non-ES proteins have average one antigenic region each 42.1 amino acids ([Table 4](#t4){ref-type="table"}). The AAR value for the 48 ES proteins supported at RNA level which are specific of the *T. solium* secretome was of 28.3. Interestingly, all ES proteins datasets had twofold more antigenic regions in comparison with the non-ES proteins of the *T. solium* genome ([Table 4](#t4){ref-type="table"}). Hence the epitope density in ES proteins is higher than for non-ES proteins. For the validation of biological significance of AAR values, we calculated this value for a dataset of experimentally derived ES proteins of *T. solium*


compiled from literature (see materials and methods). This set contained 46 protein sequences that have been experimentally reported to be useful in the diagnostic of human teniosis or neurocysticercosis ([Supplementary Table S5](#s1){ref-type="supplementary-material"}). Interestingly, the AAR value for this antigenic protein dataset was 21.8, which is close to the calculated value for the secretome ([Table 4](#t4){ref-type="table"}). In contrast, the non-ES proteins showed an AAR value of 42.1. Interestingly, 44 (95.6%) of the 46 diagnostic proteins were found in our secretome ([Supplementary Table S5](#s1){ref-type="supplementary-material"}). Furthermore, we also found RNA support for these 44 proteins ([Supplementary Table S5](#s1){ref-type="supplementary-material"}). To test whether our obtained AAR values are similar to other known secretomes, we selected the secretomes of 12 helminth species which were recently reported in the Helminth Secretome Database (HSD)[@b2] and theirshowed a statistical overrepresentation in the ES proteins of peptidase activities, extracellular organization and cell adhesion terms. Proteins with peptidase domains have been previously reported to be involved in virulence activity in several helminth species[@b51]. Several ES proteins were predicted to be involved in antigen processing and presentation pathway. Interestingly, there is evidence that secreted glycoantigens by cysticerci can modulate the host inflammatory response through the activation of dendritic cells in the experimental murine cysticercosis caused by *T. crassiceps*[@b52]. However, the relevance of ES proteins on the modulation of host-parasite relationships has not been studied in human cysticercosis. Although, it is well known that helminth ES proteins can modulate the host immune system during the infection for parasite survival[@b13][@b14][@b15].

The functional annotations found in the *T. solium* secretome by


applied. SignalP was used to predict classically secreted proteins, setting the option for eukaryote organisms and the positional limit of 70 residues for truncation before submitting it to the neural networks algorithm. The input sequences also may include TM regions and the D-cutoff values were setting as default. SecretomeP was used to predict the non-classical secreted proteins using the default options for mammalian organisms. All the classical and non-classical secretory proteins were merged together and the resulting list was scanned by TargetP[@b37] to predict the mitochondrial proteins, using at 95% of specificity and the default options for non-plant organisms. The mitochondrial proteins predicted by TargetP were discarded from the protein data set. The resulting ES proteins were subsequently scanned for the presence of transmembrane helices by TMHMM (versionis for adults and mostly business day. So “hugging” someone is totally awkward for Japanese.

Since that you should find accommodations close to or along the beach, discover your best bets to your famous hotel Zone, which is actually 14 mile peninsula into the Caribbean Beach. Our pick for the best hotel in Cancun is the Barcelo Costa situated on their own Playa Linda Beach in Cancun. This resort is close on the golf course, shopping in addition to course, the beach.

This isn’t the grapes fruit I am talking in regards to. but rather, this is an factor that is popularly used in skin care products to retain your skin moisture delighted. It is a powerful antioxidant that can help off the free radicals that’s the attacking the skin


It is contended the information fails to state a public offense for the reason that it is not specifically alleged that the defendant knew his machine had struck the deceased; that the court erred in giving and refusing to give instructions to the jury, and that there is a fatal variance between the allegations of the information and the proof which was adduced.
 The evidence shows that the defendant and his older son jointly owned the automobile which was involved in the accident. At 8:30 o'clock in the evening of November 8, 1936, the defendant was riding in the rear seat of his machine, which was then being operated by his younger sixteen year old son, who was not the joint owner of the vehicle. The operation ofand did fail to immediately stop said motor vehicle involved in an accident causing injuries and death to another person and to render aid as provided in Section 482 (a) of the Vehicle Code."
 Since the amendment of section 952 of the Penal Code in 1929, greater liberality is allowed in determining the sufficiency of the allegations of an information or of an indictment. By the terms of that section, as amended, it is declared the information may be drawn "in the words of the enactment", or "in any words sufficient to give the accused notice of the offense of which he is accused". The defendant in the present case knew that his machine had hit and injured or killed a pedestrian at a time and place which


the contrary. He also admitted he was joint owner of the car. He had the absolute right to direct and control its operation at the time of the accident. There is no conflict of evidence in that regard.
 On the authority of People v. Kaufman, 49 Cal.App. 570 [193 P. 953], since, under the provisions of sections 480 and 482a of the Vehicle Code, the driver of a machine might be guilty of only one of several distinct acts of omission, each one of which may constitute a separate offense, the appellant contends it was error for the court in this case not to instruct the jury to that effect, for the reason that it cannot be determined from the verdict whether all jurors agreed upon the guiltarmed with two 2,000 pounds Mk. 84, two AIM-9J Sidewinders, two 370 gal. external tanks under the wings and one 300 gall tank under the belly.

[Read also: Israeli Air Force strikes Syria for the second time. Syrian air defenses unable to react.]

As told by Norton, the Israeli jets flew more than 600 miles in the skies of three supposedly enemy nations: to reach the target, the first country that the aircraft overflew was northern Saudi Arabia and its deserts.

The route over Iraq was planned not only to avoid the radar coverage but also the airfields; inbound to the target the F-16s flew at an altitude between 150 and 300 ft.

At 17:35 with the sun at their back complicating any intercept attempt, the aircraft arrived over the target: before


4?
-1/3
Which is the nearest to -1?  (a) 2  (b) -5  (c) 0  (d) -0.09
d
What is the nearest to -61 in 3, 3/2, 4, -1/4?
-1/4
Which is the nearest to -5/3?  (a) -4  (b) -5/9  (c) -4/9
b
What is the nearest to 45 in -1/7, 0.2, 39?
39
Which is the nearest to -2/5?  (a) -2/7  (b) -1  (c) -1/4
a
Which is the closest to -1/4?  (a) 92  (b) 3/4  (c) -0.2
c
What is the closest to -6 in 0, -1, -0.2, 1?
-1
Which is the nearest to 2/5?  (a) -2  (b) 1/3  (c) 3.4
b
What is the nearest to 1/3 in -0.2, -0.017, -0.1?
-0.017
Which is the nearest to 0?  (a) -2/13  (b) -0.5  (c) 3  (d)Pink Pickled Onions
8 ounces champagne vinegar
1/2 cup sugar
2 serrano chiles, seeded
2 thinly sliced medium red onions
In a small saucepan,
bring the vinegar, sugar,
and chiles to a boil.
Stir until sugar is dissolved.
Remove from heat.
In a plastic container,
place the sliced onions
And pour the liquid over them.
Place the container in an
ice bath to cool.
Serve chilled with meats
OR seafood.
These are also great on sandwiches
http://luv2garden.com/pickle_recipes.html


easy for us to make the same mistakes with less fanfare. Someone has an idea, we see potential problems the initiator doesn’t see and rather than be the naysayer in the crowd, we go along. When the situation then turns sour, we are either in the “I told you so,” or the “I knew it wouldn’t work” seat. Either seat should be uncomfortable; how much better it could have been to be sitting in the winners’ box with a team that succeeded.
In the alternate scenario, we are sometimes the initiator who gets so caught up in the idea that we lose sight of the larger goal.
As momentum builds, we increasingly underestimate potential problems and don’t build solutions into the plan. In the process, we are also likely totelephone calls from Boswell's home continued, showing a "marked increase" in June 1999 when Boswell demanded that Blake accompany her on a camping trip and other activities, which Blake refused. Finally, in June, Blake demanded that Boswell "should forever and finally cease from pressuring [her] for sexual favors."
On or about June 30, 1999, at a meeting attended by Blake, Boswell and Lynnette Heiges, the Human Resources Representative for PTC in Arlington, Boswell handed Blake a termination letter which she had written. The letter stated that Blake had been on probation since May 19, 1999, because of her inability to effectively service the account of The Federation of State Board Physical Therapy, a PTC client for which Blake was the primary designated travel agent. The letter purported to base


conveniens. Considering the "private" and "public" factors set forth in Gulf Oil Corp. v. Gilbert, 330 U.S. 501, 67 S.Ct. 839, 91 L.Ed. 1055 (1947), the judge concluded that "Virginia has the closer ties to this litigation" in part because PTC's "business in the District of Columbia was limited, relative to the amount of business conducted in Virginia"; the decisions not to promote Blake and to terminate her were made in Virginia or at corporate headquarters in Colorado; and the "impact of the [sexual] harassment is alleged to have affected plaintiff on her job which was primarily in Arlington, Virginia." The judge also reasoned that Virginia would not be an inconvenient forum for Blake to litigate the case. In dismissing, the judge stated that she "[could not] concludeand her status as a PTC director and supervisor is what implicates the corporation in conduct forbidden by the District's anti-discrimination statute. See Burlington Indus., Inc. v. Ellerth, 524 U.S. 742, 762, 118 S.Ct. 2257, 141 L.Ed.2d 633 (1998) (a "tangible employment action," which is "the means by which [a] supervisor brings the official power of the enterprise to bear on subordinates[,]... becomes for Title VII purposes the act of the employer").[6]
For these reasons, none of the Gulf Oil public factors can reasonably be said to have warranted dismissal of Blake's suit. It is not a controversy "local" to Virginia which that state has a paramount interest in resolving; it will not burden the Superior Court with the "congest[ion of] foreign litigation"; and it will not unfairly impose


protein abundance does not always correlate well with mRNA abundance. Therefore, the use of proteomics methods has provided a powerful approach to explain more directly the process of SE. In fact, many studies on SE have been conducted in the proteomes of economically important plant species such as maize (*Zea mays* L.) \[[@pone.0119987.ref008],[@pone.0119987.ref009]\], *Medicago truncatula* \[[@pone.0119987.ref010],[@pone.0119987.ref011]\], grapevine (*Vitis vinifera*) \[[@pone.0119987.ref012],[@pone.0119987.ref013]\], *Cyclamen persicum* \[[@pone.0119987.ref014],[@pone.0119987.ref015]\], orange tree (*Citrus sinensis*) \[[@pone.0119987.ref016]\], date palm (*Phoenix dactylifera* L.) \[[@pone.0119987.ref017]\], and tamarillo (*Cyphomandra betacea*) \[[@pone.0119987.ref018]\].

To date, increasing studies have focused on protein expression during embryogenesis in conifers. Lippert et al. \[[@pone.0119987.ref019]\] indicated some important proteins that involved in SE in white spruce. In addition, a differential proteome analysis of ECs with different maturation capabilities in Brazilian pine \[[@pone.0119987.ref020]\] was carried out. More recently, Teyssier(clusters) of differentially expressed proteins. Proteins of the four clusters belonged to different functional categories and clearly indicated dynamic changes in the proteins involved in the development of *L*. *principis-rupprechtii* somatic embryos. This work provides novel insights into the process of larch embryo development in vitro and a framework both for study of the biological processes as well as opportunities for practical application of this knowledge.

Materials and Methods {#sec002}
=====================

Tissue culture and sample collection {#sec003}
------------------------------------

The BL2e cell line established at the National Engineering Laboratory for Tree Breeding (BJFU, Beijing, China) was selected for this proteomic study. The embryogenic material was subcultured biweekly on maintenance medium. Samples collected from separate clumps of proembryogenic masses (PEM) were considered to be single biological replicates. Proteomic sample collection was according to Lippert's method


determined using the Bradford assay \[[@pone.0119987.ref022]\]. 1D SDS-PAGE was performed to separate proteins (50 μg of each sample) on the first dimension. Sixteen fractions in each lane were divided and carefully excised from the gel lanes and transferred to 2-mL centrifuge tubes. Gel fractions were destained with 50% acetonitrile (ACN) and 25 mM triethylammonium bicarbonate (TEAB) overnight and subsequently dehydrated with ACN until bleaching. Proteins were reduced with 10 mM DTT at 56°C for 1 h, alkylated with 55 mM iodoacetamide (IAM) at room temperature for 1 h, and then centrifuged at 20,000 × g for 30 min. The resulting pellets were washed twice with 25 mM TEAB and twice with destaining solution, and ACN was added to repeat the dehydration step. For protein digestion, enzyme stock solutionand the percentage and number of proteins allocated to each function is presented in [Fig. 4](#pone.0119987.g004){ref-type="fig"}. Among the enriched categories based on BP, proteins involved in metabolic processes and cellular processes were well represented at 65.6 and 76.0%, respectively, of the differentially expressed proteins. Of the MF category proteins identified in this study, proteins involved in binding and catalytic activity were in the majority, accounting for 72.9 and 41.7%, respectively. In the CC class, GO terms were enriched for the cell and organelle parts with 63.5 and 56.3%, respectively. Proteins involved in developmental cytoskeleton organization and binding accumulated during the early stage of *L*. *principis-rupprechtii* somatic embryo development from the PEM stage to the GE stage. GO terms that were overrepresented in the PEM stage, decreased during the


content (99.10±0.06%). When cultures were transformed to maturation medium, their water contents were dropped significantly at GE stage (77.38±12.01%), and with a continued decline at CE stage (68.07±6.67%).

![Water content changes during somatic embryo development.\
Percentage of water content during SE was calculated as (FW-DW)/FW. Bars represent standard errors (n = 5). Significantly different groups are indicated by different lowercase letters (*P* \< 0.05).](pone.0119987.g005){#pone.0119987.g005}

Enzyme activity assays {#sec015}
----------------------

Since the iTRAQ data indicated that oxidation-reduction is one of the most responsive pathways during somatic embryo development ([Fig. 6A](#pone.0119987.g006){ref-type="fig"}), SOD and CAT assays were performed to further validate our iTRAQ result. As shown in [Fig. 6B](#pone.0119987.g006){ref-type="fig"}, total SOD activities increased by 112% from PEM to GE, but no significant changes occurred from GE to CE ([Fig. 6B](#pone.0119987.g006){ref-type="fig"}). At GE and CE stages, totalof newly synthesized proteins to prevent them from misfolding or aggregating. Several HSP family proteins including heat-shock cognate protein 70--1 (HCP 70--1; F4KCE5) and luminal-binding proteins (BiPs; Q42434 and Q40924) were upregulated markedly between the PEM and GE stages, and downregulated during the CE stage. HSPs were reported previously in many studies to be present throughout embryogenesis \[[@pone.0119987.ref021],[@pone.0119987.ref056]\]. Likewise, BiPs have been reported to play a role in binding nascent polypeptides to induce correct folding and seed development \[[@pone.0119987.ref057]\]. We hypothesize that high expression of HSPs during the globular stage is part of a general stress adaptation process that implies a fine regulation of auxin and stress signaling when PEMs are transferred to ABA-containing hypertonic medium.

Glycine-rich RNA-binding proteins (GRPs; P84976) are a class of RNA-binding proteins involved in


                white(.6) 70%,
                                                       white(0) 75%),
                    radial-gradient(ellipse at right center, white(.3) 40%, white(0) 40%),
                    linear-gradient(to bottom, lighten(crimson,20), firebrick),
    Review: Tanks By Paul Devlin

The first time I heard about Tanks it was presented as a bit of a joke – nothing more than another X-Wing clone only with lumbering, earth bound hunks of metal replacing zippy space ships locked in do or die interstellar dogfights. How could a semi-realistic portrayal of World War II tank combat, including build your own, Airfix-style models, ever hope to compete with Fantasy Flight’s evergreen, and ever expanding, Star Wars miniatures game?

Yet, only a few weeks later and with my first couple of games under my belt, I was getting messages from those I had duelled with showing me pictures of their multiple Tanks purchases. You see, there is a magic to Tanks that is turning it from a tabletop curio into


[@B020]-[@B022], which is important for the regulation of osteoblast differentiation. Although Wnt/β-catenin signaling is crucial for BMP9-mediated induction of osteogenic differentiation, the role of the Wnt inhibitor Dkk1 in the crosstalk between Wnt/β-catenin and BMP9 signaling remains to be fully elucidated.

In this study, we sought to determine whether Dkk1 plays an important role in BMP9-induced osteogenic differentiation of MSCs. We found that Dkk1 expression was upregulated by BMP9 in a dose-dependent manner in C3H10T1/2 cells. Inhibition of P38 by SB203580 reduced the expression level of Dkk1 induced by BMP9. BMP9-induced osteogenic differentiation was inhibited by overexpression of Dkk1. Moreover, Dkk1 blocked BMP9-induced Wnt/β-catenin signaling activity. Taken together, our results suggest that BMP9 upregulates Dkk1 expression via the P38 MAPK pathway, and Dkk1 plays an important role in theleaving full-time work to have children. 'Too far away' Tom Wainewright, 25, an architectural assistant living in east London, said starting a pension was way down his priority list. Unfortunately the tide has turned and younger people face even more challenges in saving for their retirement

Ed Gardner, pension and insurance firm Metlife "I haven't given a pension any thought," he said. "At the moment I'm just trying to keep down a steady job. I was made redundant because of the recession and have had to take a pay cut." Other young people said they had not started a pension because they did not know how to, or else felt retirement was too far away to be worth planning for. Despite only 36% of respondents under 30 having a


have a bubble area for kids young and old. Get them to try and catch the bubbles before they’ve hit the ground.

Be open to suggestions.

Five-year-olds are very inventive, so let them throw in a few ideas about the games they’d like to play. If they’re not dangerous or inappropriate let them enjoy themselves. Often parents will plan so many fun activities and games, only for the group to invent their own crazy game.

Do you have any tips and tricks for kids’ birthday parties? Let us know in the comments below or on Twitter and Facebook.In April, a St Louis area single mom lost her day job when her employer discovered her out-of-hours work: blogging about her polyamorous escapades. The woman – whose blog is called 'The Beautiful Kind' (or TBK) – was unmasked thanks to cached copy available on Twitter search engine Topsy: her full name (which she'd entered, then deleted) was still listed next to her nickname in the search engine.

Thanks to TBK's story, Topsy no longer displays a user's full name next to his or her Twitter nickname, even if the user has associated the two. "We may add [full names] back in the future, after we can fill in the gaps in the existing system," Topsy spokesman Brian Merritt tells Inc.com. "The story of the blogger and our disappointment


I’ve previously mentioned may have a solution. Tapping into this revolution may very well be one of the most important things you do for your brand this year. Experts are saying, for instance, that VR will change television as we know it forever.

Certainly, there’s a major opportunity cost involved. Only you can decide whether or not investing in marketing via VR -- or any other new technology this year -- will be the right fit for your brand. But by remaining open to these new opportunities, you’ll avoid becoming one of the brands left in the dust behind more forward-thinking competitors in 2016.

What do you think your biggest marketing challenge will be in 2016? How are you planning to tackle it? Let me know in the comments below.soon as possible, and getting your product in to peoples’ hands to test your ideas.

For the vast majority of people on our course, the EP is just an academic exercise. The real point of the EP, from an academic point of view, is just to apply some of the things you have learnt over the previous two terms. For that reason we are pretty much obliged to shoehorn in references to various frameworks such as Porter’s Five Forces at every opportunity.

I think most of the students are in agreement that if we were to pass our EPs on to real investors for investment, the first thing we would do is strip them of most of the “MBA talk”. It would certainly shorten them substantially!

The first result in a


Badu – they were great guides – and we had a pretty good time talking about their business over lunch, where we threw about a few new ideas that could be explored with their core idea. A great first day!

*what’s nerdier than having a blog? Having two blogs of course! I have about four so go figure…

**can’t tell you what it means – that’s between me and the team (and everyone else at MEST).

I’m sitting in San Francisco airport awaiting my flight back to London so I’ve just got time to crank one last Silicon Valley trek blog post out.

Friday morning we visited Kiva. I had heard of them as we have a couple of classmates that have worked with them, but I didn’t really know what theyEntrepreneurial School of Technology and was in Ghana last week. This was actually one of the best meetings of the week. Fellow MEST MBA consultant, Louis, gave a good presentation about Meltwater and set us the challenge of suggesting some business areas Meltwater could move in to. Then a Meltwater sales director gave us an hour of B2B sales training, which was really good actually as, strangely, sales training doesn’t appear on any MBA curriculum for some reason. We then did some role-playing in pairs pretending we were selling Meltwater services to each other. At the end of the session I suggested about 6 companies that Meltwater could acquire. I’ll take the credit, and commission, if they ever move in on these companies.

In the afternoon we had no


of Saudi officials removing the sign of the office of pilgrims affairs in Mecca belonging to Iran, and some Iranian social media users began to call for a boycott of the hajj, which will take place in September.

Iranian member of parliament Mohammad Ali Esfanani, spokesman for the parliament’s Judicial and Legal Committee, said the termination of diplomatic relations means that the hajj should also be suspended.

The hajj pilgrimage is mandatory for Muslims who are able to afford it. Umrah pilgrimage, which is not mandatory and can be undertaken at any time of the year, was suspended in April after two Iranian boys were sexually assaulted by Saudi security at Jeddah airport.

Esfanani said that while the hajj is mandatory, it can be excused when there are difficult circumstances. HeGroovyMBean accessing attributes is like accessing properties on a object and we can invoke a operation directly by its name.

In our example code we inspect some MBeans provided by the Jetty webserver. To enable JMX in Jetty we invoke the following startup command:

$ export JMX_OPTS = -Dcom.sun.management.jmxremote -Djava.rmi.server.hostname=localhost -Dcom.sun.management.jmxremote.port=8090 -Dcom.sun.management.jmxremote.authenticate=false -Dcom.sun.management.jmxremote.ssl=false
$ java $JMX_OPTS -jar start.jar etc/jetty-jmx.xml etc/jetty.xml

Jetty starts with an unsafe JMX connection. We can use it for this example, but for production system we must enable ssl and enable user authentication. Some Jetty components are now exposed as MBeans and in the following piece of code we inspect these MBeans. We see how to read and write attributes and how to invoke methods with GroovyMBean.

import javax.management.remote.*
import javax.management.*
import groovy.jmx.builder.*

// Setup JMX connection.
def connection = new


large quantities of sand and gravel.  Many people believe that South Maury Island is one of the most sensitive places to mine due to the amount of wildlife the area supports; however, Glacier Northwest claimed that mining on the island and barging the gravel off the site will have fewer environmental impacts than would mining somewhere else and transporting the gravel by truck. Grassroots efforts and litigation have successfully postponed the proposed expansion yet.

According to Glacier Northwest's website, the island is the largest supplier of aggregate in the Pacific Northwest, creating a need for it to continuously extract aggregate so that it can remain the largest supplier.  Preserve Our Islands, a volunteer non-profit organization claims that if Glacier Northwest continues to expand, nearly ten percent ofMaury Island will be affected.  They also argue that the near shore location of the gravel pit will endanger the eelgrass habitat, which is vital for salmon to spawn.  POI also argues that toxins will contaminate the island's only source of drinking water and will affect the residents as well.

Glacier Northwest's proposed mining expansion has stirred response in the government. U.S. Senator Patty Murray, a senior member of the Appropriations Committee, has pushed measures for economic development and environmental and public safety initiatives throughout Washington, one of which concerns the conservation of Maury Island. Providing approximately $2 million, this bill would contribute to the goal of local organizations, such as POI, of preserving the threatened 250 acres (1 km²) that are home to the state's largest Madrona


also be much lower, depending on demand. Also dependent on demand is the lifetime of the mine, which could be 11 years at full production, up to 35 years before the site is closed. The clearing of ground is proposed to occur in phases of 32 acres (129,000 m²) each, with no more than two phases in process at a time. In order to reduce arsenic contamination, contaminated materials will be contained within a sealed berm, and no contaminated materials will leave the site.

Also stated in the EIS are alternative actions that Glacier Northwest proposes to take in order for them to mine at the Maury Island site, including reduced hours of barging to control noise, mitigation of the Madrone forest, habitat retention for the pileated woodpecker byareas of the Pacific Northwest.  However, the barge traffic itself could increase pollution levels, and also increase the chances of possible collisions with endangered marine mammals who reside in or pass through the area.  One of the arguments against the transportation of the rock is that the new dock that would be built for it has much potential for the destruction of vital habitat for sea life.  The impact could be lessened if Glacier Northwest replaces or mitigates any damages caused by the dock.  Another worry of the Preserve Our Lands and other groups is the possible arsenic contamination of the drinking water.  This could be offset by large containers that could contain the waste from the mining. However, what would happen to


the arsenic after has been contained has yet to be addressed in detail.  Other benefits of the mining are the large number of jobs the mine could create, and the boost to the local economy that the mine might produce.  However, the mine could also negatively affect tourism and property values in the area.

References

Further reading

"Belcher Specifies Aquatic Reserves."  Seattle Post-Intelligencer.  Seattle, WA: November 21, 2000.
Bentler, Fred. Department of Natural Resources and Parks. "Water and Land Resources Division." May 9, 2005, Website: “https://web.archive.org/web/20050303170846/http://www.audubon.org/bird/watchlist/bs-bc-washington.html%E2%80%9D
“Biological and Ecological Characteristics.” The University of Washington Arbutus Page. 2005. 17 May 2005. <www.students.Washington.edu>
Brown et al. Reptiles of Washington and Oregon. Seattle Audubon Society, 1995.
Christie, Patrick.  Assistant Professor, School of Marine Affairs and the Jackson School of International Studies.  "Growthand ease of application and processing. The coatings furthermore have a controlled microporosity depending on the size of the particulate non-reactants as well as the thermal conditions during the micropyretic reaction along the combustion front.
When these refractor coatings are applied to a substrate, for instance of graphite or anthracite-based carbon, refractory material or steel used in an aluminium production cell in contact with the molten electrolyte and/or with molten aluminium, the coating protects the substrate against the ingress of cryolite and sodium and is in turn protected by the protective film of aluminium on the coating itself.
The invention also relates to an aluminium production cell comprising a coated component as discussed above as well as a method of producing aluminium using such cells and methods of servicing and/or


produced refractory material is usually selected from the group of borides, silicides, nitrides, carbides, phosphides, aluminides or oxides, and mixtures thereof, of at least one metal selected from titanium, zirconium, hafnium, vanadium, silicon, niobium and tantalum, nickel, molybdenum, chromium and iron, as well as metal alloys, intermetallic compounds, cermets or other composite materials based on said metal or mixtures thereof or mixtures with at least one of the aforesaid compounds. The refractory borides of titanium, zirconium, hafnium, vanadium, niobium and tantalum, or combinations thereof with the other listed materials are preferred.
The micropyretic slurry comprises particulate micropyretic reactants in combination with optional particulate of fibrous non-reactant fillers or moderators in a carrier of colloidal materials or other fluids such as water or other aqueous solutions, organic carriers such asis afforded the opportunity to see each player's wager action prior to acting. The button player can thus gain a sense about each player's hand before deciding what action to take (wager, call, raise or fold). The button player is always the last player to act until such time as the button player folds, whereby the player acting immediately prior to the button player becomes the last player to act.


In typical computer systems a processor, dynamic random access memory (DRAM) controller, or similar apparatus executes commands. Execution usually involves performing some operation on data that is stored in a memory location and referenced using an address. For various reasons, for instance to increase the rate at which a processor can execute commands, commands may be scheduled by a computer system to be executed in a different order than the order in which they were issued. Out of order execution can improve system performance but also introduces the possibility of errors. For example, when a read command is scheduled to be executed out of order in advance of a write command that originally preceded it, the data read upon execution of the read command may not be thewhere 1 is the maximum command address span. If some false positive indications are acceptable, the hardware requirements may be reduced somewhat. In this situation hazards may be indicated where they do not actually exist. This is somewhat undesirable because when hazards are detected, system operation is slowed by the system taking steps to prevent commands from being reordered around the hazardous command. For some systems or applications, however, a number of false positive indications will not impact performance.
Even systems that can tolerate some false positive indications may still be unable to use prior hazard detection methods if large numbers of outstanding commands may exist. What is needed is a method for detecting reordering hazards that is not dependent on the number of outstanding commands and that requires


done in mainstream OS since a
few decades.

 _Memory-conserving modularity tools_ , whatever that might be, aren't VM
specific.

The only issue you are right about, is that bytecode is much more compact than
native code.

> ... the reason there hasn't been a lot of new work on the JIT may be that
> the JIT is as good as it can be without eating more battery.

The current JIT is good enough for developers writing CRUD applications, HTML
wrappers or the "fart app" of the month.

Those of us that care about performance use the NDK anyway.

~~~
Zigurd
> Those of us that care about performance use the NDK anyway.

If you had said "People porting game engines implemented in C use the NDK
anyway" you might be right, and they do that because re-coding the game engine
is impractical,The whole idea of force opioid tapering and what it is doing to pain patients continues to rear its head.

This Monday, Nevada pain physicians are expected to descend upon the state capitol in Carson City and make the case that the regulation of pain management is a big issue that needs attention.

In Oregon, despite intense opposition from pain professionals across the country, The Oregon Health Authority is moving toward imposing a forced opioid taper policy for Medicaid patients in March. We’ll be reporting more on that in the coming days.

And to update you on a story on the National Pain Report story that ran last weekend, during the last week Vi Pfeiffer of Helena had her prescription reduced again this month—this time in half–the fourth straight month her


and avocado oil. These fats aren't recommended for cooking because heat can oxidize them, turning them from friend to foe. Use MUFAs on salads, or drizzle them on cooked foods.
  * **Saturated fats:** Saturated fats have suffered an unfair reputation as a heart disease villain. The truth is that saturated fats have been an important and beneficial part of the human diet since our cave-man ancestors gnawed on a nice, fatty chop. Saturated fat is solid at room temperature, and our favorite source is coconut. Coconut oil is ideal for cooking because it can withstand higher temperatures. Coconut flakes, coconut milk, and coconut butter are also delicious, healthful options. You should also feel free to indulge in the luscious fat found in organic, grass-fed, pastured meats andsome key concepts that are necessary in any successful exercise program. It also looks at common questions or concerns when it comes to exercise — whether you're training for strength or fat loss — such as whether you're doing too little or too much and fears about "bulking up."

Paleo fitness is about doing the least amount of work you need to do to get the job done, but that work won't be easy. To be frank, this chapter discusses what may very well be the most intense form of exercise you've ever experienced.

Heinous, diabolical, merciless, inhumane, and monstrous are just a few of the adjectives used to describe _metabolic conditioning_ — the practice of taxing multiple muscle groups and energy systems simultaneously. Get ready to add your own


[Application of a modified tympanic membrane surgical knife with suction and tube device in myringotomy with ventilation tube placement].
Objective:To explore the efficacy of a modified tympanic membrane surgical knife with suction and tube device in myringotomy with ventilation tube placement for the treatment of secretory otitis media.Method:From June of 2014 to December of 2015, 87 cases of secretory otitis media were randomly divided into two groups: One group was treated by general approach to achieve tympanic membrane tube insertion, and another group with modified method. The total effective rate，the rate of tube detachment at 3 months postoperatively, the rate of scar formation or tympanic membrane atrophy, the operation time and the success rate of tube insertion for the first time in two groups were analyzed retrospectively. Result:There wasis then linked to the release of potentially toxic metal ions, which can cause cell death [6, 19, 20]. It remains somewhat a matter of debate to what extent any observed effects are either due to the NPs themselves, the metal ions already present in the extracellular medium due to pre-dissolution of the NPs at neutral pH, or the metal ions released intracellularly after cellular NP uptake [6]. In most cases, all three components will contribute to the observed cellular effects, but intracellularly released ions have been suggested to locally reach high levels which can exceed toxic thresholds and hereby induce cellular damage at levels where free metal ions that distribute more homogenously do not cause such effects [6].

A third paradigm is the disturbance of cellular autophagy levels


used cell types, being human bronchial epithelial cells (BEAS-2B) and murine mesenchymal stem cells (MSCs).

Fig. 1

Representative transmission electron microscopy images of the Au (left) and SiO2 (right) NPs used in the present work

Nanoparticle-mediated cell death and oxidative stress

As a first step, both cell types were exposed to a wide concentration range of either NP, after which a wide number of cellular parameters were evaluated using a validated high-content imaging based procedure [5, 6, 14]. Figure 2 reveals concentration-dependent loss of cell viability with is linked with an increase of cell membrane damage. Under our conditions, significant toxicity was only observed at concentrations of 200 µg/ml for both the Au and SiO2 NPs, in either of the cell types used. As no significant membrane damage was observed at subcytotoxiccellular alterations. As SiO2 NPs did not cause any such effects, the elevated autophagy levels and loss of lysosomal activity seen for Au NP-treated cells may be involved. A near identical pattern was observed upon analysis of cellular FACs (Fig. 4b), where SiO2 NPs had only minimal effects, whereas Au NPs resulted in significant but transient reduction of total cellular FAC sizes. These data suggest that any functional effect observed will also be transient in nature. The latter may explain the high level of discrepancy observed for various NPs, mainly iron oxide NPs and their effect on stem cell differentiation. Various research groups have observed clear inhibition of chondrogenesis for iron oxide NP-labelled MSCs, while other groups saw no effect of the iron oxide NPs, even when identical


activity (a5). Mitochondrial damage and accumulation of autophagosomes lowers cellular ATP levels which in turn stimulates RhoA activity. Upon recovery of the cellular degradative capacity, autophagosome clearance occurs more efficiently (a7), which reduces cellular autophagy levels and Rac and Cdc42 activity. The low ATP levels then result in increased RhoA activity, which will return back to baseline levels as turnover of damaged mitochondria occurs more efficiently. RhoA activity will restore the cellular cytoskeleton and actin-mediated signaling. SiO2 NPs also enter the cells and induce ROS (b1), which affects mitochondrial health. This stimulates autophagy (b2) which promotes clearance of the damaged mitochondria. Upon fusion with the lysosomes, mitochondrial turnover remains normal, resulting in an efficient management of cellular ATP levels

Overall, the Au NP-elicited effects are mainly caused by theexpressed as the fold increase of a certain parameter (cell death, membrane damage, mitochondrial ROS, mitochondrial stress, cell area, cell skewness, autophagy levels, endosomal size, endosomal pH, focal adhesion complexes) compared to the control levels where the level of increase is indicated by colour-codes.

Evaluation of RhoA, Cdc42 and Rac1 activity

MSC and Beas-2B cells were seeded in 25 cm2 collagen-coated tissue culture flasks at 1 * 105 cells/flask and allowed to settle overnight. Next, cells were incubated with fresh media (10 ml) containing the Au or SiO2 NPs at 150 µg/ml for 24 h. Media were removed, cells washed twice with ice-cold PBS, and cells were then either kept in culture for an additional 2, 4 or 6 days or processed immediately. At these time points, cell lysates and


barriers with regard to strength and quality of the app included limited longer term client engagement with the app ("Like a lot of other apps, you use it for a month...and then you start losing touch with it" \[Addiction Treatment\]) and questions about impact with dissemination to a broader client base ("I think if you have too many people on this...you kind of get lost in the whole cyberspace thing of who is this person---anybody could be on there...you want to keep it small so people feel comfortable actually interacting and putting messages on there...you get more interaction when people know each other" \[Addiction Treatment\]).

### Relative Advantage

Perceptions of relative advantage of the recovery support app over usual care also facilitated implementation across service sites, particularly with regard toongoing client support:

> A lot of people who deal with drug issues are pretty solitary people...so it's hard to get them to open up. When you're doing it through the application, it's somewhat anonymous...you're not standing face-to-face...and it makes it a little bit easier to develop friendship.
>
> Drug Court

Stakeholders generally did not indicate perceived relative advantages of the app with regard to their own workflow (eg, "Does it save me...on paperwork or phone calls? I would not say either. It's probably just the same" \[Addiction Treatment\]).

### Ease of Use

Perceived ease of use of the app was a facilitator to implementation across settings (eg, "It is a very safe app; anything you press it easily directs you to go right back to it" \[Addiction Treatment\]).

### Trialability and Adaptability

The ability


design and ease of use of the A-CHESS app allowed clients to easily learn to use the app with practice.

### Outer Context

Agency policies prohibiting client use of mobile phones and more stringent privacy regulations for particular subpopulations (ie, drug court--involved) can introduce barriers to implementation of mobile substance use treatment technologies. In some cases, liabilities related to specific technology features, such as location tracking, may need to be turned off to proceed with use of the tool for other capacities. In many cases, agency policies can also be changed. Thinking systemically, an innovation can be adapted to improve fit during implementation; organizations can also adapt to accommodate the innovation \[[@ref40],[@ref41]\]. Key to any policy change is use of data to demonstrate value, such as improving clients' health andwellbeing and promoting health service quality and efficiency. Furthermore, organizations are encouraged to adapt the innovation to the needs of the agency and client subgroups. Although efforts should be made by people at adoption sites to maintain the core elements of the intervention \[[@ref42]\], scholars are increasingly rejecting the assumption that an intervention will yield diminished benefit for clients after being modified to fit real-world delivery settings \[[@ref43]\].

### Postlude: Sustainability

The focus of this implementation process study was a single point in time relatively early in implementation. In a separate study of A-CHESS sustainability among consortium members, 3 agencies had sustained use of the recovery support tool at 24 months, 2 of which were agencies studied here (Veterans Substance Use Treatment and Addiction Treatment) \[[@ref38]\]. It may be that


to pass the carbon capping bill.

“Finally this week, the governor called me, said she wants to talk to me, we have to resolve this,” Baertschiger said. "And I came back to Oregon by myself.”

Baertschiger said he also spoke individually with Senate Democrats opposed to the climate bill, to confirm they opposed it. "So here we are,” he said.

Sen. Elizabeth Steiner Hayward, Senate Democrats’ deputy majority leader, called for members of both parties to be on their best behavior this weekend, given the heated political rhetoric throughout the walkout.

"I hope that everybody, Democrats and Republicans alike, chooses to be on their most professional, civilized behavior over the next couple days, so we can get the people’s work done,” Steiner Hayward said.

— Hillary Borrud | hborrud@oregonian.com | 503-294-4034 | @hborrud

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      2014, uses he/him pronouns, and identifies as trans masculine and pansexual.

Career
Alexander's debut acting role was on Netflix's The OA, where he plays Buck Vu. Buck, like Alexander, is also a transgender youth and was partially based on Alexander's real experiences. He was cast from an open casting call online that spread through Tumblr. Later he was cast in the 2018 feature film Every Day, based on the book by David Levithan, playing Vic, a trans teen whom the spirit "A" inhabits for a day. In October 2017, Naughty Dog announced Alexander had joined the voice cast for The Last of Us Part II, the sequel to their popular video game.

In June 2019, to mark the 50th anniversary of the Stonewall Riots, sparking the start of the


and also allowing youngsters to participate adequately.

Although much of the point of two player perfect information games is that you can calculate the best move, if you’re good enough, this isn’t what gamers look for nowadays. They want games where they can employ intuition rather than logic, and where the choice of moves is pretty limited.

I agree that multiplayer helps on average (although the best-selling version of Pentago is the 2-player version, not the multiplayer version, so it’s not always true).

I disagree with the notion that “much of the point of two player perfect information games is that you can calculate the best move”. Modern abstracts tend to have larger branch factors than older abstract games, and as the branch factor grows, intuition becomes increasingly important compared to/*
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 Redistribution and use in source and binary forms, with or without
 modification, are permitted provided that the following conditions
 are met:
 1. Redistributions of source code must retain the above copyright
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split skirt over breeches that allowed her to sit astride. She looked over at Thranduil and smiled. His attire was the same green jacket he had worn when she first laid eyes on him. Elves did not seem to feel the need for change that Mortals did.

"I am just remembering when we first met. How happy I felt when I rode home behind you."

"It is a sweet memory for me too," he said. A wide grin split his face. "Galion, take Sigrid's reins and lead her horse. My love, come here. Ride pillion behind me, as you used to do." He held out his arms and drew her across to him. Sigrid settled herself on his horse's rump and put her arms around his waist. "Comfortable?"

"Very comfortable, Thranduil,"she whispered, nestling her cheek against his broad back. "But is this proper?"

He laughed and looked about expectantly. "Well? I am waiting. Does not the sight of an elf-man riding in joy with his leman before the eyes of all bring on Ardhon Meth?"

"No, Sire," Galion muttered. "The end of all things is not upon us. However, you may make a few Beornings swoon."

"Then let them look, and let them swoon," Thranduil laughed. "I could ride like this all the way to Gondor."

Sigrid flicked her eyes back over the rest of the mounted train and the troop of pikemen who marched as guards. Everyone's eyes were straight ahead, their faces impassive. If Thranduil wished to flaunt her, there were none among his folk who dared to speak otherwise.


same as last time."

The two men shut the door and proceeded on, leaving Sigrid alone in the chamber. She washed her hands and face and dried them on a soft towel. The room was on the third floor, and the single window looked out into the canopy of trees. The scent of the purple flowers blew in on the warm breeze. Sigrid looked out for a time, down onto a walled garden with espaliered fruit trees and other shrubs. Then she went and sat down on the bed. The narrow bed.

She sighed. Had she truly expected to be treated any differently than Galion or the other servants? At the very least, her stay in Ithilien would be restful, although Sigrid felt she would miss lying beside Thranduil. Shehad grown accustomed to his comforting presence in the night, even though he tended to steal the covers and nick the backs of her ankles with his toenails. With a smile, she recalled Asa making the same complaint about Wulf years before. Truly, when it came to sleep, all men were alike; the similarities between Elf and Mortal exceeded the differences.

"Surprise!"

Sigrid looked up to see Thranduil in his shirtsleeves silhouetted in a connecting doorway, an impish grin upon his face.

"I must have raised my son right, for he and his butler are both thoughtful and discreet. I daresay no one will take any note of who sleeps where. We will use this room to store the clothing, for the bed in the next one is much more to


advise you to take that tone with him when he comes next month with King Elessar and Queen Arwen. That axe he carries is no mere decoration, and he has quite a temper."

"Oh, won't that be fun! Parading King Thranduil's kept woman in front of the King of Gondor! Tell me, Glavras, how does your Elven-lord plan to handle that sticky problem?"

"Prince Legolas does not share these protocol decisions with me, fortunately," said Glavras. "However, I am sure she will be treated with the courtesy due any guest, for it is none of our business what the lady is to Thranduil or he to her."

"Now who's being a fool?" Heledir laughed.

The two of them left then, and Sigrid finally dared to breathe again. She stared down at the---
abstract: 'We present lightcurve observations and multiband photometry for 107P/Wilson-Harrington using five small- and medium-sized telescopes. The lightcurve has shown a periodicity of $0.2979$ $day$ (7.15 $hour$) and $0.0993$ $day$ (2.38 $hour$), which has a commensurability of 3:1. The physical properties of the lightcurve indicate two models: (1) 107P/Wilson-Harrington is a tumbling object with a sidereal rotation period of $0.2979$ $day$ and a precession period of $0.0993$ $day$. The shape has a long axis mode (LAM) of $L_{1}$:$L_{2}$:$L_{3}$ = 1.0:1.0:1.6. The direction of the total rotational angular momentum is around $\lambda=310^{\circ}$, $\beta=-10^{\circ}$, or $\lambda=132^{\circ}$, $\beta=-17^{\circ}$. The nutation angle is approximately constant at $65^{\circ}$. (2) 107P/Wilson-Harrington is not a tumbler. The sidereal rotation period is $0.2979$ $day$. The shape is nearly spherical but slightly hexagonal with a short axis


that then trigger 107P’s cometary activity. Post-MBC, 107P is capable of becoming host to water-ice, organics, and aqueous alteration materials. In this hypothesis, the impacts’ influence would be apparent in the rotational states and/or the surface color variations.

We had an opportunity to observe 107P from August 2009 to March 2010. Our long observation campaigns enable us to derive the rotational states, shape model, and rotational color variations. Furthermore, the orbit of 107P makes it accessible by spacecraft. A more advanced sample return mission from a D-type asteroid or an asteroid-comet transition object is envisioned in Japan. One candidate is 107P [@Yoshikawa08]. Clarification of the physical properties of 107P is important to the design of the future mission. If we are able to obtain 107P’s physical properties, the datalong enough from November 2009 to February 2010 when the data are utilized for the analysis. Thus, the offset is negligible. Furthermore, the apparent magnitude change of 107P is gradual up to 1.0 magnitude per month (Table 2). The change does not act on the derivation of rotational period that is expected to be from three to seven hours according to past reports.

In contrast to the relative photometry of the lightcurve, more photometric precision is required to detect the rotational color variation by multiband photometry. In order to improve the photometric precision, we averaged three consecutive images of 107P for the BSGC’s data and 14–16 consecutive images of 107P for the OAO’s data. We also measured the flux of ten standard stars from SDSS data Release 7 [@Abazajian09],


    8.569376        15.308 ${\pm}$ 0.003   14.641 ${\pm}$ 0.003   14.413 ${\pm}$ 0.003   14.287 ${\pm}$ 0.004
      12.371825           8.478789        15.763 ${\pm}$ 0.004   15.298 ${\pm}$ 0.004   15.156 ${\pm}$ 0.004   15.099 ${\pm}$ 0.005

  : Standard stars in SDSS-7.

Results
=======

Rotational states
-----------------

Since the “Standard Feature ($SF$)” that is, the flux peaks and/or bottoms in lightcurves, shifts along the phase of lightcurves due to changes in the geometric relationship between the Earth, 107P, and the Sun during the long-term observations, the estimation of the sidereal rotation period for 107P requires a short-termThe two-dimensional Fourier series is described in the following form

$$\begin{aligned}
\nonumber  F^{m}(t)                 & =& C_{0}+\sum^{m}_{j=1}\left[C_{j0}\cos\frac{2{\pi}j}{P_{\psi}}t+S_{j0}\sin\frac{2{\pi}j}{P_{\psi}}t\right]\\
\nonumber            &+& \sum^{m}_{k=1}\sum^{m}_{j=-m}\left[C_{jk}\cos\left(\frac{2{\pi}j}{P_{\psi}}+\frac{2{\pi}k}{P_{\phi}}\right)t\right.\\
            &+& \left. S_{jk}\sin\left(\frac{2{\pi}j}{P_{\psi}}+\frac{2{\pi}k}{P_{\phi}}\right)t\right],\end{aligned}$$

where $m$ is the order, $C_{0}$ is the mean reduced light flux, $C_{jk}$ and $S_{jk}$ are the Fourier coefficients for the linear combination of the two frequencies $P^{-1}_{\psi}$ and $P^{-1}_{\phi}$, respectively, and $t$ is the time. Substituting $m$ = $2$, $P_{\psi}$ = $0.2979$ $day$, and $P_{\phi}$ = $0.0993$ $day$ for 107P, we obtain a fitting curve, as shown in Fig. 6. The fitting curve adequately reconstructs the trend of the lightcurve.


$day$ by retrograde motion. Impacts of small objects are suggested as a cause for the tumbling and comet activity. Alternatively, the past comet activity itself is thought to be a cause of the tumbling, like a 1P/Halley [@Samarasinha91].

2\. 107P is not a tumbler. The sidereal rotation period is $0.2979$ $day$. The shape is roughly spherical but slightly hexagonal with a SAM of $L_{1}$:$L_{2}$:$L_{3}$ = 1.5:1.0:1.0. The pole orientation is around $\lambda=330^{\circ}$, $\beta=-27^{\circ}$. The sense of rotation is retrograde. The lightcurve of commensurability would reflect a discriminative appearance like (2867) Steins, which has been explored by the Rosetta spacecraft [@Keller10]. Otherwise, the lightcurve also indicates the possibility of hosting a binary whose orbital period is $0.2979$ $day$. The existence of a binary is also consistent with the past cometarypower line inspection tedious, expensive, time-consuming, and dangerous.

At present, there have been some power line inspection methods put into practical work, which involves four main directions: foot patrol \[[@B1]\], manned aerial vehicles \[[@B2]\], climbing robots \[[@B3], [@B4]\], and unmanned aerial vehicles (UAVs) \[[@B5]\].

*(A) Foot Patrol Inspection*. The components of a foot patrol inspection team were introduced in \[[@B1]\]. Usually, a team of two people walk from pylon to pylon to inspect the power lines in the foot patrol inspection. Visual inspection is carried out with the help of binoculars and sometimes with infrared radiation and corona detection cameras. Such an inspection can be highly accurate only when the surfaces of power line equipment can be well seen from the ground. Recently, foot patrol inspection requiring the experience of


  Accuracy rate: 100%; false detection rate: 14.3%; image processing time: 2.47 s

######

Analysis of false detection.

                                             Test times under normal conditions/the number of false detection instances   Test timesthe revolt against the Romans. He is said to have prevented the Torah from being forgotten.

The Jerusalem Talmud on the other hand argues that Yehoshua was preceded by Shimon ben Shetach, who is said to have restored the Torah to its glory.

How can both men be credited with the same idea?

The answer could be that it began with Shimon ben Shetach and was consolidated by Yehoshua ben Gamla, who formulated a series of regulations governing teachers and pupils.

The subjects of study were both religious and secular – or rather, the overall theme was religious, which was a broad umbrella that covered all the things we today call secular like mathematics, anatomy, literature and language.

Religion was the overarching concern, since all wisdom and knowledge emanated from God and led


unwanted pregnancy is a “consequence” women should suffer for sex, or that women who use birth control are “hoes” and “floozies,” or that women who want their insurance to cover their medication are “shrieking,” it just reinforces the Democratic claims that the conservative movement is straight up out to get women. I argued in February 2012 that Obama punked conservatives by baiting them into spewing shockingly misogynist rhetoric, but I had no idea that, two years later, they’d still be taking the bait.Equine respiratory health can be compromised by a number of different conditions, some more severe than others. If you are a horse owner and have noticed symptoms of compromised respiratory health in your beloved animal, the most obvious being heaves in horses, then you will no doubt want to study up on what could be causing your horse to struggle with its breathing. Here is a brief description of seven things you need to know about equine respiratory health:

1. Horse heaving is also known as broken wind, hay-straw allergy, or emphysema.

2. One of the most common causes of respiratory problems in horses is COPD. COPD in horses is most common amongst horses kept in a stable. As a matter of fact, eighty percent of stable-kept horses present with


general election until after a no-deal Brexit was ruled out.

That sets the stage for another battle: whether, and when, to hold a general election. The vote on the snap general election is expected to take place between 9 p.m. and the early hours of Tuesday morning.

The success of the no-deal legislation is due in no small part to the decision last week by 21 members of Mr. Johnson’s Conservative Party to defy him on the question of whether to leave without a deal. They were expelled from the party for their defiance.

The Tory revolt against Mr. Johnson, and his ruthless purging of the rebels, have reverberated through British politics, threatening his hold on power.

The prime minister and many of his allies say that Britain must preserve the possibilitynot break that law, but insisted that he would not request an extension to the Brexit deadline as the new legislation requires if he cannot reach a deal with the European Union or get Parliament’s approval for a no-deal exit.

How Mr. Johnson plans to achieve that was not explained.

Brussels is distracted by a looming Brexit deadline.

Ordinarily, this would be a week of unadulterated excitement in Brussels. On Tuesday, Ursula von der Leyen, who is set to become European Commission president on Nov. 1, is to present her college — or group — of commissioners who will lead different policy areas of the European Union bureaucracy for the next five years.

But Brexit is threatening to put a dampener on this twice-a-decade exercise, as questions of a possible extension to


break — or just getting it done,” the Irish prime minister, Leo Varadkar, said to Mr. Johnson, throwing his own words back at him.

On a chilly, gray day, with the Irish and British flags flapping behind them, Mr. Varadkar and Mr. Johnson both spoke of the need to find solutions. But the gulf between them seemed wide.

The Irish border remains the biggest barrier to a Brexit deal. All sides want to avoid the imposition of significant checks between Ireland, a member of the European Union, and Northern Ireland, which is part of the United Kingdom. A hard border could renew sectarian tensions that raged for decades.

Mr. Johnson has rejected the so-called backstop agreement reached by his predecessor, Theresa May, which would all but keep Northern Ireland inside thea corporation in which he was interested. It will hardly be contended that the nonstockholder to whom rights were allotted and who purchased stock under the options thereby conferred, or that the Guaranty Company itself, which purchased stock under rights obtained by it, was taxable on the rights under which the stock was purchased; but there would seem to be just as much reason in taxing them on the value of the rights as in taxing the stockholders in the Guaranty Company, for all received the same sort of rights and exercised them in the same way.
In Miles v. Safe Deposit & Trust Co., supra, it was held that, where a stockholder sold rights to subscribe to new stock in a corporation, the amount thus realized was taxable


p. 80; and the administrative practice thus prescribed is entitled to great weight in determining the applicability of the statute which the government invokes. Logan v. Davis, 233 U. S. 613, 627, 34 S. Ct. 685, 58 L. Ed. 1121.
For the reason stated, we think that the decision of the Board of Tax Appeals was correct, and same will accordingly be affirmed.
Affirmed.
In search of something real.

Howard and Polly held hands as they made their way through the pines and firs to the cliff edge where the strange lights had been seen for three weeks running. The crazy-looking science guy on the news had said that similar lights had been observed in more than 11,000 locations worldwide; even the Halley VI research station in Antarctica had reported sightings over the Weddell Sea. Credit: JACEY

The city's edgelands were eerily quiet; most people had gravitated towards the built-up centres where the gathered multitudes offered a comforting, if false, glimmer of security. Others just stayed at home with loved ones to wait and hope and maybe pray that what was coming wasn't really coming.

More free stories from Nature Futures As they trudged up


the outcome was likely to be, but deep down almost everyone had a bad, queasy feeling in their guts. And then last night they'd told it all, to the whole world, because what was the point in keeping it secret any more? The sightings had been increasing exponentially, and some lank-haired numbers-geek had worked out that if something was going to happen, it was going to happen tonight. And that something was going to be bad.

Howard took a hip flask from his jacket and unscrewed the cap. He offered Polly a drink and she made a funny face.

“Where the hell did you get that?” she asked.

“It was my Dad's. I never really knew what to do with it, but tonight seemed like as a good a night asover time and expand our impacts on causes we care about. Large grants are by invitation only. Thank you for your understanding.

Please note, New Belgium Brewing Company's Grants Program is a separate and distinct entity from the New Belgium Family Foundation. You can learn more about the New Belgium Family Foundation HERE.

Categories + Application

Specifically, we focus our small grants on the following five strategies to mitigate human impacts on the planet. You can learn more about each grant category and apply for funding by visiting the links below.


The R&A finally relented on that strict policy in 2012 at Royal Lytham & St. Annes.

Now it has Wi-Fi networks, routers, live streaming, geofencing. Is there anything still ancient about the Royal & Ancient?

“Me,” Dawson said with a smile.

He retires next year after 16 years as chief executive, the last few years filled with technology changes he never imagined. He still likes the balance between old and new. The Open still is played on the same turf where Old Tom Morris and Willie Park Sr. vied for championships. The claret jug has been passed around for 86 years.

“But I think in the modern era,” Dawson said, “the way that people now embrace this technology is something that golf also has to embrace.”

Jul
16

With Wi-Fi and LED, British Open has3 code, so I'm sure that there are many parts that could be written in a cleaner fashion. I'm still open for feedback to improve my Python 3 skills (hence I'm publishing these posts), so please let me know if you know better ways to solve some challenges.


All Eyes On: Lianne La Havas

The title of Lianne La Havas’ debut, Is Your Love Big Enough?, poses a juggernaut of a question. The answer is wholly dependent on who’s listening to the British newcomer’s delicate odes to flirtation, doubt, and requisite heartbreak.

Decades in the Making

Born right on the edge of the ’80s, La Havas grew up during the melody-heavy ’90s and then soaked up the independent-woman mantras of the early 2000s. The 23-year-old singer/songwriter/multi-instrumentalist wrote her first song at 11 years old, and broke into the music industry after dropping out of college and meeting singer Paloma Faith, for whom she eventually sang backup.

Under the Influence

Though La Havas’ parents separated when she was a very small child, her music is thankfully devoid of pitiful ditties about divorce.changes in lymphocyte function following an acute bout of aerobic exercise. As addressed briefly above, however, proliferative assays can produce ambiguous results due to methodological variability (Siedlik et al. [2016](#phy214234-bib-0027){ref-type="ref"}) and a failure to quantify specific elements of the activation process. Measurement of specific immune cell functions potentially can improve the understanding of the impact of excise on immunity.

Exercise‐induced alterations in immune function have the potential to affect the interaction of pathogens with the immune system. A change in cellular activation state and/or subsequent alteration in proliferation of immune cell subsets could alter the disease state in an individual. For example, changes in CD4^+^ T lymphocyte activation could enhance an immune response and provide greater protection against an invading pathogen. Conversely, heightened cell activation may create favorable conditions


   \<0.001          54, 78^\*^    65      17            52, 77        \>0.999

Mean differences were calculated as Experiment -- Control.

John Wiley & Sons, Ltd

Exercise induced changes in expression of CD25 but not CD69 {#phy214234-sec-0016}
-----------------------------------------------------------

Surface expression of CD4, CD25, and CD69 was quantified via median fluorescent intensity \[MFI\] immediately after CD4^+^ T cell isolation (0 h) and after 24 and 72 h in culture. Notably, CD4 expression was not significantly different in cells isolated pre or post the control and exercise session (data not shown). When examining exercise‐induced changes in nonstimulated CD4^+^ T cells (Arm 1), there waselevated in the exercise session compared to the resting control session, but not to a statistically significant level (*P* = 0.07, Fig. [4](#phy214234-fig-0004){ref-type="fig"}B). Follow‐up Bayesian analyses to increase the predictive precision estimated the mean difference for CD25 expression at 72 h as 0.96 (equivalent to an increase \> 93% in the exercise session relative to the control). The 95% HDI of the difference of means includes zero, but has 96% of the credible values greater than zero. Thus, there is a strong probability that the estimated parameter is greater than zero (i.e., indicative of an exercise‐induced increase in expression). The probability that the true mean difference would be greater than a 10% increase in CD25 expression was calculated at 93.3%. This suggests there is a 93.3% chance that exercise alters CD4^+^ T cell


the exception of emtricitabine or lamivudine) based on resistance testing at screening using the PhenoSense GT assay (Monogram Biosciences, South San Francisco, CA, USA). The assay combines phenotypic test results (PhenoSense HIV) with genotypic results (GeneSeq HIV) resulting in a net assessment interpretation on the report per tested drug, that is, resistant, partially sensitive, or sensitive. The clinical cut-offs used for etravirine and boosted atazanavir were 2.9--10.0 and 5.2, respectively. Exclusion criteria included HIV-2 infection, previous failure of ≥2 PI-containing regimens, and presence of ≥1 of the following NNRTI resistance-associated mutations (RAMs): K103R, V106I, I167V, V179D/F/T, Y181I/V, and G190S.

The trial protocol was reviewed and approved by an independent ethics committee and an institutional review board. The trial was carried out in accordance with the principles of Good Clinicalwas given to the other group to offset the potential reduction in atazanavir exposure, while at the same time investigating if the higher dose of atazanavir might further affect etravirine exposure. At baseline, in both groups, one of the two NRTIs was switched to etravirine 200 mg bid. NRTIs were selected by the investigators based on resistance testing; however, tenofovir disoproxil fumarate (TDF) was not permitted. Patients who were intolerant to their NRTI could switch to another sensitive NRTI, excluding TDF. Tenofovir decreases both atazanavir \[[@B22]\] and etravirine \[[@B23]\] exposure. These decreases do not significantly affect exposure of either drug, but an additive effect could result in reduced clinical efficacy when given in combination, particularly since etravirine also reduces atazanavir/ritonavir exposure. As such, a substudy to assess the addition of


was too light, blew over, and smashed the Mickey head. We had to beg Gary for his help again. That’s why I can’t give you Gary’s email. He changed it in case we broke this one.]

On my last few lamps I have added smaller bulbs to illuminate the ears as well as the larger globe.

10. Begin with a piece of metal strapping, about 4 inches long. Bend about ¼ inch on each end so that the ends will create a “friction grip” on the flange of the 6” globe which is now visible inside the 12” globe.

Make 2 of these pieces, one for each of Mickey’s ears.

11. Cut a length of outdoor Christmas lights so that you have 2 socket and enough cord on one end to attachpicture of Gary’s finished lamp.

THANK YOU, THANK YOU to Gary for not only making our lamp post, but for nicely giving me these instructions to post!

Good luck to all those Mickey Lamp makers out there! And once again, no I won’t give you Gary’s email address!

Yes, this is my way of telling everyone that Rico is now a part of our family!

Pam called me with the update on his last owner. We had a little miscommunication yesterday. His original people lost their home. That’s when they gave Rico to their son and his girlfriend. When they split up, the girlfriend said she’d keep him.

The original woman told Pam that she and her husband didn’t sleep at all last night because they were so upset over what happened to


fine with him, except when he sleeps on her little blanket in her crate.

Pam from the shelter took him to the vet today for a wellness check. People at work think he’s a chihuahua mix with Corgi, but Pam thinks he’s full chihuahua.

But now the plot thickens:

The vet found he has an ID chip, but the phone number gave a disconnect message. Pam was going to go the address, but decided to check the number herself. It gave her another number to call and here’s the story.

First, his name is — ready? – Ricky. Oh the irony.

And he’s about 7 years old.

He belonged to a woman in our town who moved to Clementon. She gave him to a friend of her son’s and DOESN’T EVEN KNOW HIS NAME!She doesn’t want Ricky back, but doesn’t know if the son’s friend does. She can’t explain how this little dog ended miles from home.

But!

The son doesn’t come home from work until 3 am. She’ll call him in the morning and get the name & number of Ricky’s owner. Pam will check out the place and ask the guy if he wants Ricky. We all think that this guy dumped Ricky out in the woods. He certainly didn’t take good care of him, but I do admit he did feed him. He’s not starving.

So we’re waiting to here if Ricky’s going back. I don’t like the idea; I don’t think this guy is taking care of him. Unfortunately, if he says he wants his dog back, we have no


municipality "die[s] as a result of personal injury or disease arising out of and in the course of his employment with the city."
The Wheeling City Solicitor responded to the appellant in a letter dated October 9, 1998, stating that:
Mrs. Brown's death did not occur in the course of her employment under the existing law. Thus I cannot advise the Board of Trustees that there is a clearly established legal basis for them to recognize a claim for benefits under the provision of W.Va.Code 8-22-9(a)(1) in this particular case. Therefore, any such claim made to this pension fund as a result of the death of Leah Brown could not be approved as a legitimate expenditure by the Board of Trustees.
Instead of challenging the City Solicitor's opinion and seeking alegal determination regarding his entitlement to pension benefits based on Mrs. Brown's employment, under W.Va.Code, 8-22-9(a)(1) [1987], or applying for dependents benefits from the Worker's Compensation Fund, the appellant filed the instant action solely against the City of Wheeling. In his complaint, the appellant alleged that the driver was acting within the course and scope of his employment so as to bind the City to liability based on the employee driver's negligence. At the same time, the complaint alleged that Mrs. Brown was not acting within the scope of her employment with the City.
In response to the civil action filed by the appellant, the City asserted that both the driver and the decedent were employees of the City, and that the City was therefore, inter alia, immune under


right of action as aforesaid, which the employee ... would otherwise have[.]
It is the general rule in West Virginia that when an employee is injured while going to and coming from work, that employee is not considered to be in the course of his or her employment. De Constantin v. Public Service Comm'n, 75 W.Va. 32, 83 S.E. 88 (1914); Buckland v. State Compensation Comm'r, 115 W.Va. 323, 175 S.E. 785 (1931). In other words, the employee may not recover workers' compensation benefits, and the employer is not immune from a negligence action. As we stated, in Syllabus Point 1 of Carper v. Workmen's Compensation Comm'r, 121 W.Va. 1, 1 S.E.2d 165 (1939):
An employee is entitled to compensation for an injury sustained in going to or from his(and that of the Trump Administration) will weaken support for expanding opportunity. But that’s an issue that can be handled by actively opposing DeVos while also advancing choice.

What DeVos is doing in terms of operating the agency itself is of even greater concern, especially amid news this week about waylaying key civil servants who run operations below the appointed staff.

The latest news came yesterday as Politico reported that DeVos ‘reassigned’ the director of the Department of Education’s budget office, along with at least one other employee, as part of her effort to effectively eliminate that division. Apparently angered that the budget office and its boss, Erica Navarro, have defied and opposed her her reorganization efforts, DeVos moved Navarro over to the Office for Civil Rights (whose operations have


the scandal-plagued Agora Cyber Charter School in a complaint from families of its students over illegal sharing of student data with K-12 Inc., and other contractors. Some are worried that DeVos will weaken enforcement of privacy laws to help out key players in the charter school movement.

As you would expect, DeVos didn’t leave out Office for Civil Rights in her dismantling effort. Besides demoting Navarro by putting her under notorious acting boss Candice Jackson, DeVos moved Sandra Battle, who oversaw the division’s enforcement of civil rights laws, out of the office. Jackson, an opponent of civil rights enforcement and laws, will now be directly in charge. This likely means even fewer investigations into overuses of out-of-school suspensions and other forms of harsh traditional school discipline — especially sinceantibody levels increased beginning in the third week after ADI-PEG20 treatment, as shown in Fig. [2](#Fig2){ref-type="fig"}. For the 9 patients who had CR or SD after ADI-PEG20 treatment, the arginine level remained nearly undetectable for a median of 8 weeks (range 5--25) and gradually increased thereafter. One CR patient and one SD patient had low arginine levels (less than 10 μM) for 16 and 25 weeks, respectively, after ADI-PEG20 treatment. The case with CR developed anti-ADI-PEG20 antibody at a titer of 10^−2^ beginning in the second week after ADI-PEG20 and had the highest titer of the antibody (10^−6^) detected at the twentieth week after ADI-PEG 20 treatment. Another patient achieved CR after 1 cycle of ADI-PEG20, and the arginine level of this patient remained low for 5 weeks. This


BMMCs of Cases 1 and 2, respectively, before ADI-PEG20 treatment. Fifty-eight and 7 non-synonymous mutations were noted in Cases 1 and 2, respectively. Fourteen of the 58 non-synonymous mutations were predicted to be damaged or deleterious by PPH2 (PolyPhen)^[@CR24]^ or SIFT^[@CR25]^ analysis in Case 1, including *LUZP1*, *MRPL37*, *TSPYL1*, *BRAT1*, *NAB2*, *RNF31*, *IPO4*, *CEP152*, *PYGB*, *TUBGCP6*, *CAPN2*, *XRRA1*, *SPSB2*, and *GP1BA* (Supplementary Fig. [1](#MOESM1){ref-type="media"}). For Case 2, no mutations were predicted to be deleterious by PPH2 or SIFT in BMMC2B but in BMMC2A. The mutations with changes in protein coding in Case 2, BMMC2B, are listed in Supplementary Fig. [1](#MOESM1){ref-type="media"}. Some of the mutations in Cases 1 and 2 were validated by Sanger sequencing. Compared with the 3 non-responders, the mutations in *MRPL37*, *CEP152*, *PYGB*, *TUBGCP6*, *CAPN2*, *XRRA1*, and *SPSB2*potentially more responsive to ADI-PEG20. Down-regulation of genes associated with STAT5A and c-MYC was noted in the BMMCs of both responders after ADI-PEG20 treatment. We compared the c-MYC expression in BMMCs before and after ADI-PEG20 in the two responders (Cases 1 and 2) and in 5 other non-responders (Cases 4, 9, 10, 11, and 14), including 2 SD (Case 9 and Case 14) and 3 PD patients, by qRT-PCR. The c-MYC expression level was down-regulated in Cases 1 and 2 after ADI-PEG20 treatment, as shown in Fig. [4B](#Fig4){ref-type="fig"}, whereas the c-MYC expression was not decreased in Cases 4, 9, 11 or 14 after ADI-PEG20 treatment. Additionally, elevation of c-MYC was noted in the relapsed BMMCs in Case 1 (Fig. [4B](#Fig4){ref-type="fig"}). Further investigation to determine whether ADI-PEG20 inhibits AML proliferation by targeting


27 of cycle 1 and day 1 of cycles 2--6. Thus, these parameters were assessed 8 days after the prior ADI-PEG20 dose. Circulating arginine and citrulline levels were measured by mass spectrometry assays, and plasma anti-ADI-PEG20 antibodies were assessed by ELISA-based immunogenicity assay. Arginine depletion was defined as ≤10 μM. These tests were performed by Polaris Pharmaceuticals, Inc. (San Diego, CA, USA). Determination of BM ASS was recommended but not required prior to enrollment and upon BM follow-up. ASS was determined as described previously, using a Polaris antibody.

Statistical consideration {#Sec12}
-------------------------

The primary endpoint was the response rate. The second endpoints were safety, tolerability, time of treatment, pharmacodynamics and immunogenicity of ADI-PEG20 and the overall survival (OS) of the patients. Data, including the safety, pharmacodynamics and immunogenicity of ADI-PEG20, were analyzedpattern. The commonly used acupoints in patients with *deficiency of both the heart and spleen* were Xinshu (BL15), Shenmen (HT7), Sanyinjiao (SP6), Pishu (BL20), Zusanli (ST36), Neiguan (PC6), Baihui (GV20), Yintang (EX-HN3), Anmian (EX-HN22), Sishencong (EX-HN1), Fengchi (GB20), and Zhongwan (CV12). For *hyperactivity of fire due to yin deficiency*, Shenmen (HT7), Sanyinjiao (SP6), Shenshu (BL23), Taixi (Kl13), Xinshu (BL15), Baihui (GV20), Neiguan (PC6), Zhongwan (CV12), Sishencong (EX-HN1), Qihai (CV6), Yintang (EX-HN3), Anmian (EX-HN22), Fengchi (GB20), Zhaohai (Kl6), and Guanyuan (CV4) were commonly used acupoints. Sanyinjiao (SP6), Taichong (LR3), Shenmen (HT7), Ganshu (BL18), Zhongwan (CV12), Neiguan (PC6), Qihai (CV6), Fengchi (GB20), Guanyuan (CV4), Baihui (GV20), Xiawan (CV10), Shenshu (BL23), and Yintang (EX-HN3) were commonly used acupoints in patients with*liver-qi stagnation transforming into fire*. The selection of acupoints in other


deficiency of the heart and gallbladder*, it was Wen Dan Tang and An Shen Ding Zhi Wan, respectively. For other TCM patterns, no single formula could be regarded as commonly used across TCM practitioners.

We could not identify certain combinations of herbal agents or acupoints being used for particular TCM patterns. Suanzaoren (Semen Z. spinosae), Fuling (Poria), Yejiaoteng (Caulis P. multiflori), Gancao (Radix Glycyrrhizae), and Baishao (Radix P. alba) and Shenmen (HT7), Yintang (EX-HN3), Sanyinjiao (SP6), Baihui (GV20), Anmian (EX-HN22), and Sishencong (EX-HN1) were the commonly used Chinese herbs and acupoints, respectively, and they were being used nonspecifically for treating insomnia in many different TCM patterns. Treatment principles underlying the selection of herbal combinations were seldomy reported and it was more obvious with pattern-based acupuncture studies. One explanation forSearch This Blog

Cover Reveal ~ Finding Shawn by Phil Marcello

Synopsis

Alex, the rock star quarterback, appears to be basking in the limelight of his success and his new romance with Pam. But appearances can be deceiving.

Shawn is the key man in the football team’s solid defense. He’s also the senior class’ most eligible bachelor. But Shawn has no time to get involved with a girl—at least, that’s what he tells his friends.

In reality, he does have a love interest… Tony Valito.

Side-by-side, the relationships between the two couples blossom. One in the open. The other in secret. That is, until Shawn’s world erupts when the rumor that he’s gay gathers momentum.

In trying to find Shawn, perhaps his friends will end up finding themselves. And everyone will discover how dangerous are


there is a finite at which the system can no longer be efficient ([Fig. 2b](#pone-0058989-g002){ref-type="fig"}). This finding is in agreement with the results for numerical simulations of the model for finite populations (see [@pone.0058989-Seaver1] and [Fig. 3](#pone-0058989-g003){ref-type="fig"}) and with the solution of the voter model when "zealots" (agents that are always in state ) are present in the population [@pone.0058989-Mobilia1], [@pone.0058989-Mobilia2]. In the voter model, a small fraction of zealots is enough to throw the system into a negative efficiency value.

![Comparison between model simulations for finite system sizes and the mean-field results.\
We consider populations of naive agents with of conservatives or negative partisan agents with bias strength . We build a network following the model proposed by Watts and Strogatz [@pone.0058989-Watts1] using the same parameters as in [@pone.0058989-Seaver1]--. In the case with partisan agents, we show how the initial condition affects the behavior of the system as predicted. Note how there is a transition between a region in which some realizations have , to a partisan regime in which no realizations have and the efficiency is very similar to that of the mean-field approximation.](pone.0058989.g003){#pone-0058989-g003}

If the population contains a mixture of naive agents and partisan agents with equal fractions of positive and negative partisans, then one recovers as a solution to Eq. (4). Note that in such case the steady-state solution corresponds to , and , with where and .

Similarly to the case of well-intentioned agents, one can assume that close to the transition the solution is where , , and to obtain the following transition


and , with where and .

To obtain the transition line between efficient and non-efficient regimes, we thus assume that the solution to Eq. (10) close to the transition for is with . Without loss of generality, we can assume that with , , and . Introducing these solutions into Eq. (10) for each type of agent we obtain the following expressions

By imposing the steady-state condition on Eqs. (18-20), we find the relationship between and , and and and , respectively. Note that because Eqs. (19) and (20) are the same, . This means that the deviations from the steady state solution in which there are many more positive than negative partisans holding the majority opinion are the same for both types of partisans. Using that , we obtainstills show a soldier applying force against a Palestinian boy with a casted arm in an attempt to arrest him. Yet the arrest does not take place, as a half dozen female Palestinian, including young girls, slap, bite, bash and choke the soldier who calls for back-up, but ultimately abandons arresting the boy.

There is a bit of folklore around the Nabi Saleh protesters. The town’s children are known to chase down soldiers during protests, and punch, hit, and kick them. In 2012 Ahed Tamimi—the girl in the pink shirt and braids in the video above, then 12, was filmed throwing a right-hook at a soldier. She was later honored by Turkish President Recep Tayyip Erdogan with an award in courage.

Regev is a former spokesperson for the Israeli army.


geometry to add to the container.
 *
 * @return OGRERR_NONE if successful, or OGRERR_UNSUPPORTED_GEOMETRY_TYPE if
 * the geometry type is illegal for the type of geometry container.
 */

OGRErr OGRGeometryCollection::addGeometryDirectly( OGRGeometry * poNewGeom )

{
    if( !isCompatibleSubType(poNewGeom->getGeometryType()) )
        return OGRERR_UNSUPPORTED_GEOMETRY_TYPE;

    if( poNewGeom->Is3D() && !Is3D() )

        set3D(TRUE);

    if( poNewGeom->IsMeasured() && !IsMeasured() )

        setMeasured(TRUE);

    if( !poNewGeom->Is3D() && Is3D() )

        poNewGeom->set3D(TRUE);

    if( !poNewGeom->IsMeasured() && IsMeasured() )

        poNewGeom->setMeasured(TRUE);

    OGRGeometry** papoNewGeoms = (OGRGeometry **) VSI_REALLOC_VERBOSE( papoGeoms,
          eErr = OGRERR_FAILURE;
            else
                eErr = ((OGRGeometryCollection*)poSubGeom)->
                        importFromWkbInternal( pabySubData, nSize, nRecLevel + 1, eWkbVariant );
        }
        else
        {
            eErr = OGRGeometryFactory::
                createFromWkb( pabySubData, NULL,


  if( bHasZ ) flags |= OGR_G_3D;
    if( bHasM ) flags |= OGR_G_MEASURED;
    if( bIsEmpty )
        return OGRERR_NONE;

    char        szToken[OGR_WKT_TOKEN_MAX];
    const char  *pszInput = *ppszInput;

    /* Skip first '(' */
    pszInput = OGRWktReadToken( pszInput, szToken );

/* ==================================================================== */
/*      Read each subgeometry in turn.                                  */
/* ==================================================================== */
    do
    {
  nSkip, "M ") )
                nSkip += 2;
            if( STARTS_WITH_CI(papszGeoms[iGeom] + nSkip, "Z ") )
                nSkip += 2;

            /* skip empty subgeoms */
            if( papszGeoms[iGeom][nSkip] != '(' )
            {
                CPLDebug( "OGR", "OGRGeometryCollection::exportToWkt() - skipping %s.",


Developing patient registration and medical records management system in Ethiopia.
In low-income countries, medical record management is often lacking. We sought to evaluate the impact of an inexpensive business process re-engineering project on the accessibility and completeness of patient information and on physician satisfaction. Pre-post intervention study during 2006-07, using time-motion studies, medical record audits and physician surveys. A rural hospital in Ethiopia. Medical record personnel, hospital administrators, clinical staff. We implemented a hospital-wide patient registration and medical records re-engineering process, which included a simple, custom-made computer database to manage patient information, standardized medical records forms and processes and enhanced human resource management efforts. s) We measured medical records accessibility and completeness, and physician satisfaction. Medical record accessibility and completeness and physician satisfaction improved significantly (P < 0.05) basedsleds and falling in the snow. January was occasionally cold but then it got unusually warm and there was water running in the creeks, down the ditches and even over the
roads (culverts were frozen shut). We went for trail ride to the lake BEFORE it rained and the landscape became a skating rink. Writing about that reminds me that we went to the neighbours
and the crew got to play shinny on their skating pond. At the end of the month it went back to being winter!

I can't remember if the Groundhog saw his shadow, but that day we were blessed with a nice black heifer calf--I had known about it's imminent arrival when the vet
pregnancy tested, so I had taken the cow to M's Ms in January. One


On the
last day of June the last calf of the 2015 season arrived and we were finished early morning maternity rounds. :>)

Canada Day saw the crew load up 4 horses and the decorator side boards for the truck and we headed over to Loon Lake for the Canada Day parade. Afterwards we went
down to Jumbo Beach with M's Ms crew and had a picnic lunch. Later that evening a group of us sat in the Lion's Park and watched the stage show and fireworks put on by the city of Meadow
Lake. I do feel blessed to live in Canada, where there is clean air and water, a fantastic amount of natural beauty and the folks are friendly.

The environment was very dry at the beginning of July and raintime we reached the yard site and dismounted. Everyone was grateful to climb into a warm truck.

The second last weekend of the hunting season brought my brothr-in-law, Fritz and nephew, Dylan, to the ranch to go deer hunting. I told them that if they saw a particularly fat one, I had my name on it. I even went out and pushed bush for them
on Brandy, but I'm not sure if I helped or hindered. The deer I saw moving, were going away from the hunters; however the hunters circled around and eventually got a nice fat doe. The next morning they came back and got a second one!! I was gone that day so I never even saw that one.

That was the day we helped at the Two


during this year. Helpers who arranged their stay here many months in advance,
volunteers that suddenly discovered they were looking for a different host and found me, visitors who were recommended by friends and family to try our hospitality, friends that returned for yet
another opportunity to experience Winning Ways, parents and grandparents who asked for lessons for their child, riders that wanted to grow their confidence, teachers who felt that Winning Ways
could offer so much to their students, all these folks are my friends--how blessed I am! I also know that I am enormously grateful for the friends
that I have known for many years and with whom I enjoy so many adventures.

When visitors leave they generally do so with a small photo as a reminder of their stay here.
UsuallyNow I know better. Every
day was like a lesson, the most exciting lessons I've ever had, full of joy, friendship, knowledge as well as anger and frustration occasionally. I'm
so grateful that I was given the opportunity to stay with you and all the other wonderful people. The way you work, the way you talk and the way you teach people from all over the world inspires
me." [These are words that, as a mentor, I am extremely humbled by and very grateful to know that I made a difference in a young person's life.]

Recently I read "Wisdom is the real deal!" I think the author was telling us that an enriching
experience, that has taught us something, will lead us to choices that help not hinder us. I am so