Q:

Alternatives for Roles/Claims Access Control Systems

I am developing REST API for the growing system. And in general Role/Claims Access Control work perfecly like this.
[HttpGet]
[Route("settings")]
[Authorization(Type = AuthorizationType.Admin, Permission = Permission.StoreSettings)]
public IHttpActionResult GetSettings() { /*...*/ }

Problem occurs when I have users who can for example control access deeper like in the figure below. This is an abstract example of the system.

And if I need to query something in the one of the area, it is quite simple, but when I need to get all Items from Departments I have to write the same ugly code I can't really reuse. Not real code, but looks like this.
Db.Items.Where(i =>
    i.Stores.Any(s => s.CityId == User.CityId) &&
    Db.UserDepartmentRights.Any(udr => udr.UserId == User.UserId && i.DepartmentId == udr.DepartmentId));

It is obviouslyfor refusing to give him his daughter in marriage, and therefore imprisoned him. Subsequently, Khosrow sent troops to recover the Nu'man family armor, but Hani ibn Mas'ud (Nu'man's friend) refused, and the Arab forces of the Sasanian Empire were annihilated at the battle of Dhi Qar, near al-Hirah, the capital of the Lakhmids. Hira stood just south of what is now the Iraqi city of Kufa.

Lakhmid Kingdom facts

 Al-Hirah became the cradle of the Arabic alphabet.
 Poets born in the Kingdom included: al-Nabigha, Laqete ibn Ya'amur al-Ayadi, 'Alqama ibn 'Abada and Adi ibn Zayd. Other great poets visited, like Tarafa and Amr ibn Kulthum (who killed 'Amr III ibn al-Mundhir).
 The military of the Sasanian Empire, along with al-Mundhir III ibn al-Nu'man himself and his army, defeated the


Metabolic fate of indeloxazine hydrochloride: alpha-glucoside formation in rats.
1. After oral administration of indeloxazine hydrochloride ((+/-)-2-[(inden-7-yloxy)methyl]morpholine hydrochloride) to rats, two conjugates, which were labile to alpha-glucosidase hydrolysis but refractory to beta-glucosidase, were isolated from the urine. 2. Mass spectral and n.m.r. analyses confirmed that these conjugates were alpha-D-glucopyranosides of M-2 (trans-4-(2-morpholinylmethoxy)-1,2-indandiol) and M-3 (trans-6-[[(1,2-dihydroxy-4-indanyl)oxy]-methyl]-3-morpholinone). 3. These are probably the first examples of foreign compounds conjugated with glucose in the alpha-configuration.Tracking Ultrafast Photocurrents in the Weyl Semimetal TaAs Using THz Emission Spectroscopy.
We investigate polarization-dependent ultrafast photocurrents in the Weyl semimetal TaAs using terahertz (THz) emission spectroscopy. Our results reveal that highly directional, transient photocurrents are generated along the noncentrosymmetric c axis regardless of incident light polarization, while helicity-dependent photocurrents are excited within the ab plane. This is consistent with earlier static photocurrent experiments, and demonstrates on the basis of both the physical constraints imposed by symmetry and the temporal dynamics intrinsic to current generation and decay that optically induced photocurrents in TaAs are inherent to the underlying crystal symmetry of the transition metal monopnictide family of Weyl semimetals.


clinically relevant bleeding (p = 0.130) and death (p = 0.241). In comparisons among the four groups (elderly and non-elderly patients with and without cancer), recurrent VTE and clinically relevant bleeding were comparable (p = 0.493 and 0.227, respectively), while death was more frequent in cancer patients regardless of age (p < 0.001). The efficacy and safety of Xa inhibitors as VTE treatment were comparable between cancer and non-cancer patients, and in elderly and non-elderly patients. This suggests that Xa inhibitors may be promising drugs for VTE treatment, irrespective of age and comorbid cancer.of deceased organs recovered, transplanted and discarded in the USA (2001--2010).](ijotm-5-087-g002){#F2}

The new surgical interventions mentioned above, were strongly associated with intent to donate via DCD (*ie*, including potential DCD who did progress to donation in a timely fashion). The lesser likelihood of making the diagnosis of brain death in these patients provides a plausible explanation for at least part of the stagnant growth of DBD compared with DCD \[[@B16]\]. This observation suggests that in addition to implementation of measures intended to be life-saving by preventing herniation, there has been greater adoption of DCD donation in general. Whether this represents addition of donors who would not have ever progressed to brain death or an exchange for DCD in those who would have previously followed a DBD pathway, remains uncertain.


\[[@B16]\].

It should also be noted that our intent is not to challenge the standard of care or ICU management of patients with severe head injury; rather, we have attempted to clarify and recognize the impact these new therapies and practice shifts have on the opportunity for organ recovery from deceased donors. We do recognize however, that there may be specific cases in which there exists a choice to withdraw mechanical, ventilated or organ-perfusion support immediately or to determine if the potential donor will progress to brain death in a timely fashion. In such cases, if the dying patient had expressed a premortem intent to be an organ donor to help others, and if the ability to make the diagnosis of brain death may be imminent, we suggest thatthe conclusion that "the recovery of organs from nonheart beating donors is an important, medically effective and ethically acceptable approach to reducing the gap that exists now and will continue to exist in future between the demand for and available supply of organs for transplantation" \[[@B40]\]. A number of investigators have reported excellent short-term outcomes using these donors, and several different organ procurement organizations have demonstrated 10%--15% growth in organ donation as a result of the use of DCD donors. Multiple studies have shown that the overall results of DCD (without ECD characteristics) and SCD kidney transplants are comparable \[[@B34]--[@B36],[@B41]--[@B43]\].

Doshi, *et al*, reviewed the UNOS database (from 1998 to 2004) and showed that the 5-year allograft and patient survival rates of 66.9% and 81.3% in recipients of DCD


contact us immediately by the
e-mail address stated below, with the original e-mail(s) attached.

Fairness of Market

In
order to maintain the fairness of free market and trade, we do not
provide false images, false item descriptions, non-authorized images,
or any other means which could possibly lead to deception of users
and/or customers on eBay.

We, art-sam, as an honest
and sincere member and seller on eBay, strictly follow the guidelines
of eBay.

If you still
have any questions, please do not hesitate to contact us at
Your valuable comments are our basis to provide quality service to you."What do you want from me, Master?" "(LAUGHING)" "ROGUE:" "What's going on?" "Cerebro confirms it's the Professor's code." "You found him?" "Hello, my friends, It is good to see you again." "Professor?" "You're alive!" "If you will rendezvous with me at the following coordinates... (INAUDIBLE)" "Wait." "This is all very odd." "The Professor was not at all like himself." "Gambit, check the origin of that transmission." "GAMBIT:" "In a minute." "The Blackbird just come in." "Cyclops." "Cyclops." "Guess who we found?" "Hey, wait up!" "We have to talk!" "We have to talk!" "CYCLOPS:" "Morph said something about Sinister having the Professor." "So, we're flying into a trap." "(GRUNTS)" "Suits me." "The Professor's unnatural lack of emotion suggests coercion." "If the old man was forced to call us against


Vaccinia-T7 rescue system, we obtained six replication-competent viruses bearing scFV binding to the same HER-2 epitope but with different dissociation constants ([Table 1](#tbl1){ref-type="table"}). The viruses were designated from \#6 to \#11 to allow rapid identification of the approximate dissociation constant (*K*~d~) of the displayed scFV (*e.g.*, VSVFH-αHER2\#8 presents a virus displaying scFv with *K*~d~ for HER-2 of 10^−8^ M).

By western blot analysis of purified virions, it was observed that all the rescued HER-2-retargeted viruses expressed and incorporated into their virions a larger H (due to the size of the scFV) than the parental MV-H ([Figure 1b](#fig1){ref-type="fig"}). Incorporation of MV-H-scFV into virions was comparable between the viruses. Importantly, the inclusion of a scFV did not prevent virus replication, as all the viruses were capable of producing infectious particles inand -H, we measured the syncytial area in two infected HER-2-positive cell lines, TE671 and SKOV3ip.1. It has been reported that TE671 cells express HER-2 at a density of 4.3 × 10^3^ receptor molecules/cell while SKOV3ip.1 cells express higher levels of this protein (1.5 × 10^5^ receptor molecules/cell).^[@bib15]^

Cells were infected with VSVFH-αHER2\#6-11 and the average area of the syncytia was determined at 48 hours postinfection ([Figure 3](#fig3){ref-type="fig"}). Similar to what was observed in the CHO-HER2 cells, there is a threshold in the required receptor affinity of the scFV that allows virus infectivity. No syncytia were observed in cells infected with low-affinity VSVFH-αHER2 (\#6 and \#7), and only a few small syncytia were observed in SKOV3ip.1 cells infected with VSVFH-αHER2\#8. Viruses with a higher receptor affinity formed larger syncytia in both TE671 and


 public Int32 Length
        {
            get { return _sheets.Count(); }
        }

        #endregion

        #region Public methods

        /// <summary>
        /// Returns an enumerator that iterates through the stylesheets.
        /// </summary>
        /// <returns>The enumerator.</returns>
        public IEnumerator<IStyleSheet> GetEnumerator()
        {
            return-48px -48px; }
  &.xing{ background-position: -96px -48px; }
  &.zootool{ background-position: -144px -48px; }
  &.dribbble{ background-position: -192px -48px; }
  &.deviantart{ background-position: -240px -48px; }
  &.read_it_later{ background-position: -288px -48px; }
  &.linked_in{ background-position: -336px -48px; }
  &.forrst{ background-position: -384px -48px; }
  &.pinboard{ background-position: -432px -48px; }
  &.behance{ background-position: -0px -96px; }
  &.github{ background-position: -48px -96px; }
  &.youtube{ background-position: -96px -96px; }
  &.skitch{ background-position: -144px -96px; }
  &.foursquare{ background-position: -192px -96px; }
  &.quora{ background-position: -240px -96px; }
  &.badoo{ background-position: -288px -96px; }
  &.spotify{ background-position: -336px -96px; }
  &.stumbleupon{ background-position: -384px -96px; }
  &.readability{ background-position: -432px -96px; }
  &.facebook{ background-position: -0px -144px; }
  &.twitter{ background-position: -48px -144px; }
  &.instagram{ background-position: -96px -144px;


     /// <param name="m00">First item of the first row of the matrix.</param>
        /// <param name="m01">Second item of the first row of the matrix.</param>
        /// <param name="m02">Third item of the first row of the matrix.</param>
        /// <param name="m03">Fourth item of the first row of the matrix.</param>
        /// <param name="m10">First item of the second row of the matrix.</param>
        /// <param name="m11">Second item of the second row of the matrix.</param>
        /// <param name="m12">Third item of the second row of the matrix.</param>
         /// </summary>
        public float M32 { get { return Row2.Y; } set { Row2.Y = value; } }

        /// <summary>
        /// Gets or sets the value at row 3, column 3 of this instance.
        /// </summary>
        public float M33 { get { return Row2.Z; } set { Row2.Z = value; } }

        /// <summary>
        /// Gets or sets the value at row 3, column 4 of this instance.


          return result;
        }

        /// <summary>
        /// Creates a translation matrix.
        /// </summary>
        /// <param name="vector">The translation vector.</param>
        /// <returns>The resulting Matrix4 instance.</returns>
        public static Matrix4 CreateTranslation(Vector3 vector)
        {
            Matrix4 result;
            CreateTranslation(vector.X, vector.Y, vector.Z, out result);
           return result;
        }

        #endregion

        #region CreateOrthographic

        /// <summary>
        /// Creates an orthographic projection matrix.
        /// </summary>
        /// <param name="width">The width of the projection volume.</param>
        /// <param name="height">The height of the projection volume.</param>
        /// <param name="zNear">The near edge of the projection volume.</param>
        /// <param name="zFar">The far edge of the projection volume.</param>


  public static void CreatePerspectiveFieldOfView(float fovy, float aspect, float zNear, float zFar, out Matrix4 result)
        {
            if (fovy <= 0 || fovy > Math.PI)
                throw new ArgumentOutOfRangeException("fovy");
            if (aspect <= 0)
                throw new ArgumentOutOfRangeException("aspect");
            if (zNear <= 0)
                throw new ArgumentOutOfRangeException("zNear");
 new ArgumentOutOfRangeException("zNear");

            float x = (2.0f * zNear) / (right - left);
            float y = (2.0f * zNear) / (top - bottom);
            float a = (right + left) / (right - left);
            float b = (top + bottom) / (top - bottom);
            float c = -(zFar + zNear) / (zFar - zNear);


           return Scale(scale, scale, scale);
        }

        /// <summary>
        /// Build a scaling matrix
        /// </summary>
        /// <param name="scale">Scale factors for x,y and z axes</param>
        /// <returns>A scaling matrix</returns>
        public static Matrix4 Scale(Vector3 scale)
        {
            return Scale(scale.X, scale.Y, scale.Z);
        }

         public static Matrix4 RotateY(float angle)
        {
            float cos = (float)System.Math.Cos(angle);
            float sin = (float)System.Math.Sin(angle);

            Matrix4 result;
            result.Row0 = new Vector4(cos, 0.0f, -sin, 0.0f);
            result.Row1 = Vector4.UnitY;
            result.Row2 = new Vector4(sin, 0.0f, cos, 0.0f);
            result.Row3 = Vector4.UnitW;


                         {mat.Row2.X, mat.Row2.Y, mat.Row2.Z, mat.Row2.W},
                                {mat.Row3.X, mat.Row3.Y, mat.Row3.Z, mat.Row3.W} };
            int icol = 0;
            int irow = 0;
            for (int i = 0; i < 4; i++)
            {
US Prosecutors Seeking Legal “Options” Against Epstein “Co-Conspirator” Prince Andrew

by John Vibes

The FBI has spent months trying to get an interview with Prince Andrew about his relationship with Jeffrey Epstein, but investigators have had no luck getting him to speak on the record about the case.

New York prosecutors told the press this week that the prince has “completely shut the door” on cooperating with authorities. They are now considering what further legal action can be taken.

Andrew continues to deny any wrongdoing or knowledge of Epstein’s many crimes, despite a growing body of evidence indicating that he was involved.

Manhattan Attorney Geoffrey Berman described the prince as a “co-conspirator.”

“Contrary to Prince Andrew’s very public offer to cooperate with our investigation into Epstein’s co-conspirators, an offer that was conveyed via press


Epstein’s notorious private airplane, booked on flights that went to his property in the Virgin Islands, where the Attorney General for the territory has claimed that Epstein “held underage girls captive” as recently as 2018.

*********

(TLB) published this article by John Vibes via TheMindUnleashed.com with our appreciation for the coverage.

Pictorial content added by (TLB)

John Vibes AUTHOR & INVESTIGATIVE JOURNALIST John Vibes is an author, researcher and investigative journalist who takes a special interest in the counter culture and the drug war.

••••

••••

Stay tuned to …

••••

The Liberty Beacon Project is now expanding at a near exponential rate, and for this we are grateful and excited! But we must also be practical. For 7 years we have not asked for any donations, and have built this project with our own funds asglad you came I was doing my rounds yesterday and couldn’t find your link in my list. Weird.

I’m trying to come up with a response, but it pains me to think about this conundrum. It reminds me of the movie, “My Cousin Vinny,” where a lawyer got the boys out but just barely. Funny movie. Scary reality.


           1,566              6,550

       Unless otherwise indicated, all section references are to

sections of the Internal Revenue Code in effect for the years in

issue.    All Rule references are to the Tax Court Rules of

Practice and Procedure.    All dollar amounts are rounded to the

nearest dollar.

       After concessions by both parties, the remaining issues for

decision are: (1) Whether petitioners are liable for the

additions to tax under section 6651(a)(1) for failure to timely

file their 1991, 1992, and 1993 Federal income tax returns; and

(2) whether petitioners are liable for the accuracy-related

penalty under sectionriots and fires occurring near

their home during 1991 and the subsequent relocation of

petitioners and their family to Arizona.

     We disagree.    Mr. Terrell's testimony fails to explain how

the fires and riots prevented them from timely filing their

returns or how these occurrences prevented them from filing an

extension to file their 1991 return.     Moreover, the record shows

that despite the riots and fires occurring near petitioners'

home, Mr. Terrell's business records were unaffected and were

taken with petitioners to Arizona.      The fact that petitioners had
                               - 6 -

possession


underpayment attributable to negligence or

disregard of rules or regulations.

      Petitioners must prove that they were not negligent; i.e.,

that they made a reasonable attempt to comply with the provisions

of the Internal Revenue Code, and that they were not careless,

reckless, or intentional disregard of rules or regulations.     See

sec. 6662(c); Rule 142(a); LaVerne v. Commissioner, 94 T.C. 637,

652 (1990), affd. without published opinion 956 F.2d 274 (9th

Cir. 1992); sec. 1.6662-3(b), Income Tax Regs.   "Negligence" has

also been defined as a "lack of due care or failure to do what a
                               The National Association of Collegiate Esports (NACE) announced that it has signed a partnership agreement with Gamer Sensei to connect competitive collegiate esports players with the world’s largest and most carefully curated collection of professional coaches.

The partnership between NACE and Gamer Sensei will better enable colleges and universities launching esports departments or expanding the number of games they compete in to find qualified coaches that will lead these collegiate teams to victory.

As part of the new partnership, NACE will educate member institutions about Gamer Sensei’s coaching platform, while welcoming all members to take advantage of preferred access and rates only available to NACE members. To preserve competitive integrity, Gamer Sensei coaches contracted to member institutions will be limited to working with only one institution per season at the


gaps, but the record company baulked at such radicalism. It’s not one of the band’s finest works, but it did have an impact."

"Popular consensus" for the first rock concept album, according to AllMusic, favours Sgt. Pepper. According to music critic Tim Riley, "Strictly speaking, the Mothers of Invention's Freak Out! [1966] has claims as the first 'concept album', but Sgt. Pepper was the record that made that idea convincing to most ears." Musicologist Allan Moore says that "Even though previous albums had set a unified mood (notably Sinatra's Songs for Swinging Lovers), it was on the basis of the influence of Sgt. Pepper that the penchant for the concept album was born." Adding to Sgt. Peppers claim, the artwork reinforced its central theme by depicting the four Beatlesincreased risk of atherosclerosis, obesity, and coronary heart diseases \[[@B5-ijerph-17-00071]\]. Studies of other authors assessing the impact of saturated fat intake on metabolic health are inconclusive \[[@B6-ijerph-17-00071]\] and indicate that the physiological impact of dietary SFA depends not only on dietary source and food matrix but also on SFA type and composition \[[@B7-ijerph-17-00071],[@B8-ijerph-17-00071]\]. In milk fat, SFAs are the predominant class of fatty acids (FA), but these fats are unique as they also comprise a wide and complex variety of SFA, including short-chain fatty acids, medium and long-chain fatty acids, as well as odd and branched-chain fatty acids \[[@B2-ijerph-17-00071],[@B9-ijerph-17-00071]\]. Studies by Kim and Je \[[@B10-ijerph-17-00071]\] have shown that the consumption of dairy products may reduce the risk of metabolic diseases. Unsaturated fatty acids (UFAs) are usually called "healthy


linoleic acid *cis*9*trans*11 C18:2 (CLA) in commercial smoked and unsmoked cow cheeses and cheese-like products available on the Polish market and to compare lipid quality indices in these products.

2. Materials and Methods {#sec2-ijerph-17-00071}
========================

2.1. Materials {#sec2dot1-ijerph-17-00071}
--------------

The experimental materials were commercial rennet ripening smoked and unsmoked cheese produced with cow milk and commercial smoked and unsmoked cheese-like products available on the Polish market ([Table 1](#ijerph-17-00071-t001){ref-type="table"}). The products originated from various Polish producers and were purchased in stores in Olsztyn in the period from April to May 2018. Each sample was analyzed in duplicate.

2.2. Analytical Methods {#sec2dot2-ijerph-17-00071}
-----------------------

### 2.2.1. Fat Extraction {#sec2dot2dot1-ijerph-17-00071}

The lipids were extracted according to the modified Folch's procedure \[[@B36-ijerph-17-00071]\]. The studied material was crushed and mixed. Approximately 3 g of samples (0.01 g) was homogenized (IKA Ultra-Turrax^®^T18 digital) for\< 0.05) content of these isomers was found in unsmoked and smoked cheese-like products (1.27% and 0.77%, respectively).

It was found that, in all samples of cheeses in the group of *trans* C18:1, the highest amount of *trans*10 + *trans*11 isomers were found ([Table 3](#ijerph-17-00071-t003){ref-type="table"}). The contents of these isomers in the smoked cheeses ranged from 1.02% to 1.64%, and in the unsmoked cheeses, they ranged from 0.86% to 1.38%. Other marked *trans* isomers of C18:1 in the cheeses were in smaller amounts. In the cheese-like products, the contents of *trans*10 + *trans*11 isomers were lower (from 0.17% to 0.81% in the smoked cheese-like products and from 0.13% to 0.30% in the unsmoked cheese-like products). The conducted research showed that, in the cheese-like products, the contents of marked *trans*


^b^        (0.07--0.09)                  0.03 ± 0.04 ^c^        (0.00--0.08)                    0.15 ± 0.02 ^a^        (0.12--0.18)     ND
  **Σ OCFA ^2^**               **2.23 ± 0.09** ^b^    (2.07--2.32)       0.2 companions that took into account both rotation and the interaction between the spiralling-in component and the donor star. If the ratios $a_f/a_i$ obtained by De Marco et al. are inserted in Eq. (\[eq:ce\]), they correspond to  up to $\simeq 2$. Regretfully, similar calculations are still absent for massive binaries and one has to rely on indirect methods for evaluation of .

The attempts to find a plausible evolutionary scenario for the pulsar PSRJ 2145-0750 and the results of modelling of the population of binary pulsars (which also invokes high-mass stars) both favour ${\mbox {$\alpha_{\rm CE} \times \lambda$}}\simeq 2$ [@py98][^1]. @kal99 in her study of evolutionary parameters of progenitors of donors in black-hole X-ray binaries found that the explanation of the origin of the latter systems suggests ${\mbox {$\alpha_{\rm CE}$}}> 1$,


a test of this hypothesis, we computed a population of LMBHBs under the assumption that MSW is not operating once the RLOF occurs and have shown that in this case there remains in the Galaxy about the same number of such systems as in the case with active MSW ($\simeq10000$) but all of them are transient, according to the disc instability model (DIM) criterion of @dlhc99.

In the present paper we extend considerations of the “no-MSW after RLOF” model proposed in Paper I to the case of ${\mbox {$\alpha_{\rm CE} \times \lambda$}}<2$ and carry out a detailed comparison of the model with observations.

The model {#sec:method}
=========

For convenience we remind some basic information about our calculation of the LMBHB population.

The model of the LMXB population is obtained in two steps: (i)What happens when a dude gets kicked in the hangin' brains by an MMA fighter and American Gladiator? Well, when he's a crazy "combat expert" who's taken hundreds of nutshots, not what you think.

Apparently, this Roy Kirby guy has been hit in the balls so many times that they've toughened up and also given up on telling his brain that it hurts. Good for him? It was all worth it for them to be able to show that kick about 200 times in a five minute video. [GammaSquad via Gawker]


in the past 30 days. IMAX established a bullish 5-day simple moving average and 10-day simple moving average crossover.Stock Performance on Mondays in the past 90 days: -7.35%Stock Performance on Tuesdays in the past 90 days: -4.86%Stock Performance on Wednesdays in the past 90 days: 8.63%Stock Performance on Thursdays in the past 90 days: 7.26%Stock Performance on Fridays in the past 90 days: 8.97%Stock Rating: Hold with a score of 3/5.I had a look around the site, but couldn't find a relevant email address (only addresses for prepayment setup, etc.), although my Korean skills are...barely existent. There's a Kyobo near my house, so the next time I'm in, I'll see if I can find an email address on a bookmark or something. Sorry!

I had a look around the site, but couldn't find a relevant email address (only addresses for prepayment setup, etc.), although my Korean skills are...barely existent. There's a Kyobo near my house, so the next time I'm in, I'll see if I can find an email address on a bookmark or something. Sorry!


policy to be followed for publication of clinical trials in Indian biomedical journals. The meeting held at the ICMR headquarters on October 9, 2007, was attended by 12 editors of Indian biomedical journals. It was unanimously decided that the editors have the responsibility to promote the registration of all clinical trials being conducted in India and to urge researchers to register their trials within a stipulated time, to make the clinical trial data transparent and to enable results to be published in good journals.

On behalf of all biomedical journals published from India, we urge to all those who are either conducting and/or planning to conduct clinical trials involving human subjects, to register their trials in CTRI or in any primary clinical trial register. From January 2010 onwards, weQ:

Can I share session variables in my aspx pages and in the silverlight application?

I have to create a publish-subscribe silverlight application.  and the class that publishes the events is in a class library.
I have a .Net web solution which contains Silverlight project and an asp.net web project.
The asp.net project uses some classes in a class library. These classes expose some events and once triggered, I get the returned data and store them in my session variables.
I have created few session variables - mainly List types.
I want to launch silverlight xaml page by redirecting the user to the aspx page which contains the silverlight plugin.
I want to use the List which are in the session variables and show them in a data grid.
Can I share the session variable


gentes

References

Bibliography
 Marcus Tullius Cicero, Brutus.
 Quintus Horatius Flaccus (Horace), Satirae (Satires).
 Lucius Annaeus Seneca (Seneca the Elder), Controversiae and Susasoriae.
 Dictionary of Greek and Roman Biography and Mythology, William Smith, ed., Little, Brown and Company, Boston (1849).
 Corpus Inscriptionum Latinarum.

Category:Roman gentes
Category:Ancient Roman families
Category:Prosopography of ancient Rometwo-step protocol to generate first a mesoderm-like intermediate and subsequently convert these cells to PGC-like cells^[@CR22]^, we measured the degree of differentiation of the GCTM-2^high^CD9^high^EPCAM^high^ and GCTM-2^mid^CD9^mid^ populations using flow cytometry to quantitate EPCAM/ITGA6 double high cells which represent PGC-like cells (Fig. [2a](#Fig2){ref-type="fig"}). GCTM-2^high^CD9^high^EPCAM^high^ cells showed higher expression of EPCAM and ITGA6 at the onset, as expected. After 2 days of differentiation into mesoderm-like cells, both groups showed loss of EPCAM expression but at Day 4 after PGC-like cell induction, an EPCAM/ITGA6 double positive fraction was observed in both groups. Cultures that did not receive growth factors to induce germ cell formation contained no EPCAM/ITG6A double high population. The GCTM-2^high^CD9^high^EPCAM^high^ population had largely disappeared by the end of the time course, as noted by Sasaki et al.^[@CR22]^. The identity


including *DUSP5* (inactivator of ERK1), *DUSP6* (inactivator of ERK2), and *SPRY2*, were upregulated in the self-renewing fraction, as was *DACT1* (an antagonist of canonical WNT signaling). Negative regulators of MAPK signaling including *Dusp4* and *Spry* were recently shown to be upregulated at an early stage during dissolution of the mouse naive state^[@CR41]^. Amongst the genes expressed at lower levels in the GCTM-2^high^CD9^high^EPCAM^high^ cellular subset relative to the unfractionated population were members of the WNT signaling pathway, including *WNT4*, *FRZB*, *FZD3*, *FZD5*, and *FZD8*. Of the top 100 genes upregulated in the general population, 47 genes (all upregulated at twofold change or higher) were previously reported to be expressed at peak levels at the onset of neural differentiation in the CORTECON study of Temple and colleagues^[@CR42]^ (global analysis, Supplementaryepiblast and early post-implantation epiblast were found at appreciable levels in self-renewing hPSC in all studies. Those genes with highest expression levels in all three cynomolgus epiblast populations, or in early and late post-implantation epiblast, were expressed robustly in all hPSC subpopulations in all studies. The gene panel specific to late post-implantation epiblast and gastrulating populations was expressed at somewhat lower levels in all of our populations relative to pan-epiblast specific genes. Last, genes characteristic of gastrulation stages 2A and 2B (nomenclature, ref. ^[@CR44]^) were expressed at low levels in the GCTM-2^high^CD9^high^EPCAM^high^ and GCTM-2^high^CD9^high^ and GCTM-2^mid^CD9^mid^ subpopulations, with levels rising in the GCTM-2^low^CD9^low^ and GCTM-2^−^CD9^−^ fractions. Thus, these data support the same conclusion as PCA of the single cell data: hPSC cell subpopulations enriched for self-renewal capacity show


20 min at 4 °C, followed by incubation in a secondary antibody cocktail containing goat anti-mouse IgG2a Alexa Fluor 488 antibody and goat anti-mouse IgM Alexa Fluor 647 antibody (A21131, A21238, both from Thermofisher), diluted in 2% FBS in DMEM-F12 flow cytometry buffer, again at 4 °C for 20 min. The cells were resuspended the cells in 1x DAPI in cold mTeSR1 before filtering the suspension through a 35-µm cell strainer to remove any larger aggregates and debris. Commercial antibodies were used at the dilutions recommended by the manufacturer.

All cell sorting was performed on a BD FACSAria III, using the 100-µm nozzle at 17 psi. A custom cytometer configuration was created that used the 17 psi pressure as opposed to the typical 20 psi pressure. This was performed to minimize aggregates from dissociating into singleX. Lau, Elizabeth A. Mason.

Supplementary information
=========================

**Supplementary information** is available for this paper at 10.1038/s41467-020-16214-8.

This study was supported by the Australian Research Council Special Research Initiative in StemCell Sciences (SR1101002), and Bioplatforms Australia, through funding from the Australian Government National Collaborative Research Infrastructure Strategy. M.J.M. is a Principal Research Fellow of the National Health and Medical Research Council. M.E.B. was supported by a Bellberry-Viertel Senior Medical Research Fellowship.

Contributions of authors to drafting of specific sections of the paper are identified by name of section titles. K.X.L.: design of experiments, collection of data, and writing of the paper (Methods); E.A.M.: analysis of data and writing of the paper (Methods); J.K.: design of experiments, collection of data, and writing of the paper (Methods); D.P.D. and M.M.: design of experiments, analysis of


@Override
    public boolean isFileOpen(Path filePath) {
        return filePath != null
                && documentList.containsKey(filePath)
                && documentList.get(filePath).getDocument().isPresent();
    }

    /**
     * {@inheritDoc}
     */
    @Override
    public void openFile(Path filePath, String content) throws WorkspaceDocumentException {
        if (isFileOpen(filePath)) {
            throw new WorkspaceDocumentException(
               and respected firm - Interesting and challenging clients - Manage a ...

Law Staff :: Brisbane, Queensland :: 3 days ago

... and career development opportunities. 4. FINANCIAL SERVICES LITIGATION | SENIOR ASSOCIATE - For decades this firm has gone from strength to strength, with strategic growth ... other employee benefits. There are excellent career development opportunities as advancement prospects are based on merit and not length of service. They provide their ...

Law Staff :: Brisbane, Queensland :: 3 days ago

... and career development opportunities. 4. FINANCIAL SERVICES LITIGATION | SENIOR ASSOCIATE - For decades this firm has gone from strength to strength, with strategic growth ... other employee benefits. There are excellent career development opportunities as advancement prospects are based on merit and not length of service. They provide


We are sorry, but we are no longer able to accept telephone bookings for cutting services.

For model colouring please call our Notting Hill salon directly on 0203 873 0544 to book your appointment. Please note, we now require card payment at the time of booking. Payments are non-refundable if the appointment is cancelled less than 48 hours in advance.

WEDDINGS

BEAUTY

Vernon

Vernon has been in the industry for over 20 years. A L’Oreal Colour Specialist, he has a skilled eye for colour matching and a masterful technique. Vernon has a passion for dramatic colour transformations.

His expertise can be seen in the end result, which always looks effortlessly beautiful, healthy and glossy.

Vernon has been in the industry for over 20 years, with a VIP clientele. A L’Oreal Colour Specialist, he has awhether it’s simply adding a few layers or a total style overhaul.

Skin Test: At Hari’s, our clients’ health and wellbeing is one of our highest priorities. Although very rare, sometimes reactions to colour can happen, so in order to prevent this from happening; we operate a mandatory Skin Sensitivity test which must be completed at least 48 hours prior to any colour booking if you are a new client to Hari’s Salon.

Dog Friendly: We are happy to be a very dog friendly salon and welcome bringing your four legged friends along with you to your appointment. All that we ask is that your canine companions are fully house trained, remain on their leads and are friendly with other dogs and humans.

Cancellations: If you would like to change or


purchase.

You may cancel a Dated Booking (except for Overnight Spa Breaks) within 24 hours of receiving your Order Confirmation provided the appointment is not due to take place in the next 72 hours (or 48 hours or 24 hours in some cases, dependant on the relevant Partner Terms and Conditions). In such cases we can offer you a full refund. If, however, the appointment is due to take place within the next 72 hours (or 48 hours or 24 hours in some cases dependant on the relevant Partner Terms and Conditions), you will not be entitled to a refund or a credit note.

If you wish to cancel a Dated Booking (except for Overnight Spa Breaks) more than 24 hours after receiving your Order Confirmation, and provided the applicableLow unidirectional sodium influx into root cells restricts net sodium accumulation in Thellungiella halophila, a salt-tolerant relative of Arabidopsis thaliana.
Thellungiella halophila is a useful model species for research into plant salt tolerance. It is closely related to Arabidopsis thaliana, but shows considerably higher salt tolerance. Comparative analysis of ion homeostasis in the two species allows the identification of ion transport pathways that are critical for salt tolerance and provides the basis for future studies into their molecular features. Previous studies indicated that salt tolerance in T. halophila is accompanied by low accumulation of Na in the leaves. Kinetic analysis of net ion uptake over three days confirmed lower Na uptake and K loss in T. halophila compared with A. thaliana. Differential net Na uptake rates were still apparent


the comments.

This week, 148Apps was all about Electronic Entertainment Expo (E3) 2012. Take, for instance, Carter Dotson's report on new Xbox 360 features that may allow iOS integration: "At Microsoft’s E3 press conference, they revealed an interesting new feature that will integrate smartphones and tablets to the Xbox 360. Called SmartGlass, this is designed to operate a second screen during games, movies, and TV shows. This means that hypothetically, a game could display a map on the tablet screen, or even integrate interactive game elements like maps and play-calling in sports games.

Our kids-centric site, GiggleApps, reviewed Give A Day HD, which, as reviewer Amy Solomon states, "is a thoughtful children’s book app that helps create discussions between children and their adults about the world bigger than their families,a good feeling.

Objectives shift over the variously themed stages by including different match types. Most of the time players will be blasting a set number of enemies in arena deathmatches, but the pacing occasionally gets changed up with detours through Destroy the Object levels or a quick Rugby Riot match, which requires a number of goals to be scored by carrying a ball through goal posts. Nothing hugely innovative or different here, but it serves as a nice palate cleanser for when just blasting hordes of pirates/zombies/what-have-you gets a little old.

While the omnipresent theme song may get a bit grating and it sadly lacks the multiplayer modes of the original Xbox version, Rocket Riot still serves up plenty of good, mindless, destructive fun and bizarre quirky charm. Warm


in media or a related field. 3+ yrs of exp managing people or leading a sales team. Full info HERE (9/12) SALES RESEARCH, DIRECTOR >>

ION/NYC: Oversee the Sales Research team and arm the Sales group with network performance metrics, competitive advantages, and thoughtful research stories. 7-10 years of Sales Research exp within the media industry. Strong leadership skills, analytical comm & presentation skills. Full info HERE (9/12) NETWORK SALES, ACCOUNT EXECUTIVE >>

ION/NYC: Focus on developing new and growing business among major agencies via strong relationships and superior client service. 5+ yrs of sales exp w/national cable, broadcast ad sales or media buying background required. Full inf o HERE (9/12)

DIRECTOR, STUDIO & TECHNICAL OPERATIONS>> NBCUniversal/NYC: Seeking top candidate who can maximize all operations of Net News, Sports, Enter, and[Effect of HCG administration in the gossypol-treated male rats].
The effect of gossypol acetic acid (GAA) on the pituitary-Leydig cell axis was studied. Adult male Wistar rats were administered orally 5 mg/kg/day GAA for three weeks, 10 mg/kg/day GAA for three weeks or 20 mg/kg/day GAA for two weeks. Each group was treated for four days with saline or 500 IU human chorionic gonadotropin intraperitoneally injected. None of the rats died. The mean body weight in each group was increased, but the mean body weight gain in the 20 mg/kg group was significantly lower than that in the controls (p less than 0.01). There was no significant change in the weight of testes or epididymis in any group. The serum level of lactate dehydrogenase, follicle stimulating hormone and testosterone


was significantly lower in the animals treated with 20 mg/kg/day GAA for two weeks than in the controls (p less than 0.05). No change was seen in other groups. The serum testosterone level after HCG stimulation (HCG 500 IU intraperitoneal injection for 4 days) was significantly lower in animals treated with 20 mg/kg/day GAA for two weeks (p less than 0.01). GAA is suggested to affect the pituitary-Leydig cell axis and directly inhibit Leydig cell function.working app that you can modify to fit your needs

Configuring the server

We will build off the iOS Quickstart for Twilio Notify which uses Node.js on the server side to authenticate the iOS app.

Begin by cloning this repository for the Node server in your terminal:


My santa shipped out a little bit late. At first I were beginning to think he/she maybe forgot about me.. But then he/she came through and wrote that he/she had shipped out. Apparantely there had been some trouble with acquering one of my gifts.

The package came to my local post office the 30th of December and I had my SO pick it up for me. She removed the customs declaration so I wouldn´t be spoiled in advance. How kind =)

My santa got me exactly what i wanted, and needed. An activity tracking wristband. The Xiaomi Mi Band. And also, because cooking is a big interest of mine, a quirky little cooking timer in the shape of a gingerbread-man.

I still haven´t had the time to properly set up theCyamemazine decreases ethanol intake in rats and convulsions during ethanol withdrawal syndrome in mice.
The effect of cyamemazine a dopamine D2 receptor antagonist on voluntary ethanol consumption in rats and on ethanol withdrawal in mice was examined. Male Sprague-Dawley rats were tested in a free choice (water and 10% ethanol) experiment and consumed 5 g/kg ethanol daily. Rats were treated daily IP with cyamemazine (0.5, 1, or 2 mg/kg) or acamprosate (100 mg/kg) during 2 weeks. Both acamprosate and 1 mg/kg cyamemazine significantly decreased ethanol intake by 45% without affecting either fluid or food intake. The lowest dose of cyamemazine had no effect on alcohol intake but increased food intake. The highest dose had no effect on any variables. During the post-treatment period, only 1 mg/kg cyamemazine decreased both


a possible means to meet the energetic demands for maintaining homeostasis. Metabolic rate, glycolytic activity and leptin increase during periods of hyperglycemia associated with acute osmoregulatory stress as well as during tumorigenesis ([@B8], [@B11], [@B17]--[@B21]). On the other hand, metabolic suppression as seen with hypoxia and hibernation is also associated with enhanced glycolysis, as animals attempt to meet energy requirements through anaerobic pathways ([@B12], [@B22]). Evidence in a wide range of vertebrates also show that leptin increases with hypoxia ([@B13]--[@B15]). Metabolic regulation of glycolysis is mediated by an array of factors, including hormonal signals. For instance, sympathetic catecholamines act via cAMP to either stimulate (muscle) or inhibit (hepatic) glycolysis; while insulin and hypoxia-inducible factor 1 may work through AKT-signaling pathways or by inducing gene transcription of genes involved96-well plate containing Modified Kreb\'s bicarbonate Ringer (320 mOsmolal) solution with addition of glucose (5 mM), L-glutamine (2.05 mM), and Eagles MEM (Gibco, Grand Island, NY) whereby pH of the media was adjusted to 7.4. Tissues were incubated at 24°C in a humidified environment containing 95%O~2~/5%CO~2~ at 60 revolutions per minute. Following a 2-h preincubation, the media was replaced with fresh control or experimental media containing recombinant tilapia Leptin A (rtLepA, dosages indicated in figures and legends), the dominant leptin paralog in teleost fishes ([@B30]), and/or pharmacological agents at concentrations and time periods provided in the figures ([@B33]). Media was removed and frozen at −20°C for subsequent lactate measurement. Tissues were removed and placed in either RNALater at 4°C for assessment of gene expression or in phosphofructokinase (PFK)


       - call HellbladeGame-Win64-Shipping.exe+1ABB230			<<< CONTINUE HERE
;HellbladeGame-Win64-Shipping.exe+1801AF3 - 48 85 C0              - test rax,rax
;HellbladeGame-Win64-Shipping.exe+1801AF6 - 74 1B                 - je HellbladeGame-Win64-Shipping.exe+1801B13
;HellbladeGame-Win64-Shipping.exe+1801AF8 - 48 83 B8 70050000 00  - cmp qword ptr [rax+00000570],00 { 0 }
;HellbladeGame-Win64-Shipping.exe+1801B00 - 74 11                 - je HellbladeGame-Win64-Shipping.exe+1801B13
;HellbladeGame-Win64-Shipping.exe+1801B02 - F3 0F10 83 0C090000   - movss xmm0,[rbx+0000090C]
;HellbladeGame-Win64-Shipping.exe+1801B0A - 0F2F 83 F8080000      - comiss xmm0,[rbx+000008F8]
;HellbladeGame-Win64-Shipping.exe+1801B11 - 76 5E            al and return, as we have to return the call here not in the original code
	mov al, 01h
	ret
originalCode:
	push rbx
	sub rsp,20h
	mov r8b,01h
	xor edx,edx
	mov rbx,rcx
exit:
	jmp qword ptr [_timestopInterceptionContinue]	; jmp back into the original game code, which is the location after the original statements above.
timestopInterceptor ENDP

END


40k persons list twice.
Try to use raw_id_fields in the admin for your director and actors fields.
Please see Django documentation
and this article about very long list (with an example with ForeignKey but it should also work with ManyToManyField)

Q:

How to make a minutely cronjob on debian?

How to make a minutely cronjob on debian?
Can someone help me?
The "action" should be "php /var/www/cronjob/index.php"
i have no idea!

A:

* * * * * php /var/www/cronjob/index.php

1: * = every minute
2: * = every hour
3: * = every day of month
4: * = every month
5: * = every day of week

A:

*/N     *     *   *    *        /path_to_php/php /var/www/cronjob/index.php
N - number of minutes. and you may need to specify full path to php (/usr/local/bin/php or whatewer)


about to enjoy a free $4,000 vacation and what we were
supposed to do in return. As it turns out, we weren’t expected to do very much.
Enjoy yourself, learn about the country, and take it from there. Alright, I
thought, I can do that.

So, for the next 10 days we embarked on a non-stop trip
around a country the size of Vancouver Island. There was never a moment that we
weren’t doing something. Whether it was rafting in the Jordan River, riding a
camel in the middle of the Negev or walking around Jerusalem in 40 degree
Celsius heat, there was no time to rest. The days started at 6am and they ended
at 3am. Hike in the Golan Heights, eat a shwarma in Eilat, see the sunset over
a beach in Netanya, and play cardsPFU/mL ([Figure](#f01){ref-type="fig"}).

Microplaques formed in Vero-E6 cell infected by Rio Mamoré virus with addition of dimethyl sulfoxide 0.6% in medium-viscosity overlay medium. Shown in 40X (A) and 1,000X (B).

Neutralising antibodies against RIOMV were observed in 16.21% (6/37) of the patient sera. Neutralising antibody titres ranged from 10-80. The titre of the neutralising antibodies could not be correlated with evolution (survival or death) of the patients, as shown in [Table](#t1){ref-type="table"}. Additionally, the neutralising antibody titres could not be correlated with the titres obtained using IgG-ELISA and the N recombinant antibody of ARAQV as an antigen. For example, the serum from one fatal HCPS case (patient 9) ([Table](#t1){ref-type="table"}) exhibited a 6,400 titre in the IgG ELISA, but exhibited only a 40 titre in the neutralisation test.

TABLEComparison of neutralising and nonneutralising antibody


a multiple of 24?
True
Is 28 a factor of 2197/13 - 2/2?
True
Is 11 a factor of 20/(-40)*(1 + -527)?
False
Suppose 5*l = m - 104 + 546, m + 178 = 2*l. Let x = l - 6. Let k = -50 + x. Is 16 a factor of k?
True
Let m = 1 + 27. Suppose 26 = y - 4*a, m = 4*y + a + 2*a. Is y a multiple of 10?
True
Is 20/6*3/(-12)*-42 a multiple of 4?
False
Let t(i) = 3*i**2 - 2 - i**2 - i + 3 - 3. Let a = -7 + 11. Is 7 a factor of t(a)?
False
Suppose 2*d = 2*p - 187 + 55, 0 = -p - 4*d + 61. Is p a multiple of 15?
False
Let j(z) = -627*z - 133. Letp(x) = 2*x**2 + 6*x + 6. Is p(u) a multiple of 14?
True
Let a(d) = -4*d - d + 2 + 4*d. Let v be a(0). Is 2 a factor of (3 - 1 - v) + 2?
True
Suppose -3 + 1 = -n. Let f be 55/(-20) - n/8. Is 4 a factor of (-1)/f - 58/(-6)?
False
Let w(k) = -3*k - 39. Does 3 divide w(-18)?
True
Let p = -2 - -7. Suppose 5*o + 8 = p*b - 17, -3*o = 3*b - 9. Let y = 6 - o. Does 3 divide y?
False
Let p = 1 + -1. Let s = p + 6. Does 7 divide (-43)/(-3) - 2/s?
True
Suppose -14 = -2*t + 3*p, 0 = t - 5*p - 18 - 3. Suppose 9 =


beach would be invited to join, with the tagline "You, on Full Blast" at its heart. The plan was to have people running back and forth from Stations 1 to 3 in the blistering summer heat. Don't worry, they weren't heartless and thus, no dangerous acrobatics were involved. All they wanted to test if Berocca can really give you the nutrients you need to perform all tasks under intense weatherwith the help of Berocca Performance, which is all vitamins and minerals in a glass. That means no caffeine, no sugar, and no artificial stimulants.

Curious onlookers were offered a cup of the fizzy neon drink and as they sipped and, if they presented a Berocca tube (empty or recently purchased), they get to sign up for a dynamic gamealways an issue for fans but I think the fans accept now that this is something we have to do. Almost all of the big stadia have been named now."

Sports Direct, the UK's biggest sports retailing group, recently became the club's official merchandising supplier. The company's owner Mike Ashley is already a large shareholder in the Scottish Third Division side.


then, Tofu, we don’t say things like that, do we?” said the teacher. “Let’s just move on. What have you brought in Pansy?”

Pansy unwrapped a china object she had taken from her bag and held it up for the others to see.

‘Well now, “ said Miss Malaren Hope. “That’s a very pretty little… what do we think it is?”

“A salt cellar?” asked Larch.

“That’s a very intelligent suggestion, Larch,” the teacher encouraged. “It looks Victorian to me. Victorian things are very old, boys and girls. The Victorians loved china. They made some very pretty things.” She paused. “What exactly is it, Pansy dear?”

“My granny’s ashes,” said Pansy. “Not my whole granny. Just some. They keep a bit of her in this.”

There was silence. One or two of the childrendata is typically stored on-chip in non-volatile memory. In some CPLDs, configuration data is stored on-chip in non-volatile memory, then downloaded to volatile memory as part of an initial configuration (programming) sequence.
For all of these programmable ICs, the functionality of the device is controlled by data bits provided to the device for that purpose. The data bits can be stored in volatile memory (e.g., static memory cells, as in FPGAs and some CPLDs), in non-volatile memory (e.g., FLASH memory, as in some CPLDs), or in any other type of memory cell.
Other programmable ICs are programmed by applying a processing layer, such as a metal layer, that programmably interconnects the various elements on the device. These ICs are known as mask programmable devices. Programmable ICs can also be implemented


transcends race — just check out some of the tats on your white-supremacist cousins the next time they show up at your family picnic.”

I first stumbled onto “Ask a Mexican” about a decade ago, and it was a little bit like being hit by lightning. Here was a writer who was both mouthy and erudite. He took serious topics — like racism — and made them blisteringly funny. He deployed Spanglish slang without feeling like he had to explain it to death. And did it all while waxing poetic about things like the “mexcelente Mexi-mullet” of Los Tigres del Norte bassist Hernán Hernández.

For the OC Weekly, Arellano wrote about a host of other things too: music, food, culture and the sexual abuse scandals plaguing the Catholic Church inpike position, I couldn't help thinking that maybe I could be a genius too if only I meditated longer and better.

The stress-reducing benefits of meditation notwithstanding, most people would rather do just about anything than sit still and do nothing. For those trying to develop a regular practice, even washing the dishes or doing laundry can seem like scintillating alternatives.

Then there are those few for whom meditation can become compulsive, even addictive. The irony here is that an increasing body of research shows that meditation -- in particular Buddhist Vipassana meditation -- is an effective tool in treating addiction.

One category of meditation addiction is related to the so-called "spiritual bypass." Those who experience bliss when they meditate may practice relentlessly to recreate that experience, at the expense of


bidirectional. Excitingly, the interactive signal transmission has been proved to be involved in different kinds of diseases. Abundant work indicated that gut microbiota indeed plays a predominant role in the appearance of visceral pain and provides an infusive research interest in pathological pain linked to gut dysbiosis. The emerging role of gut microbiota in neurological diseases, including chronic pain, has attracted ever more traction recently.

Currently, the relationship between gut microbiota and pain modulation has attracted more and more clinicians' attention along with the advancement of medical science. A growing body of research showed that bacteria could activate nociceptors directly via their products and constitutive elements \[[@CR5]\]. During infection, bacterial formyl peptides induce calcium flux and action potentials in nociceptor neurons and thereby result in mechanical pain sensitivity inendothelial growth factor-B (VEGF-B) via microglial AHR, further impacting proinflammatory activities of astrocytes \[[@CR116]\]. Notably, derived from tryptophan, AHR ligands are generated by certain types of bacteria, including *Lactobacillus* \[[@CR50]\], *Peptostreptococcus* \[[@CR51]\], and *Clostridium sporogenes* \[[@CR52]\] (Table [1](#Tab1){ref-type="table"}). On the other hand, TGFα produced by microglia facilitates axon regeneration and increases neuronal survival by inducing astrogliosis and neuroprotective factor generation in SCI models \[[@CR117], [@CR118]\]. Thus, we conclude that microglial TGFα promotes salutary astrocyte activities. Currently, the use of commensal bacteria to control TGFα--ErbB1 signaling via AHR has been proposed as an alternative strategy for treating SCI \[[@CR119]\]. Therefore, targeting of AHR is likely to establish a microbiota-microglia-astrocyte-oriented treatment for NP.

#### Enteric glia {#FPar8}

In the enteric nervous system, enteric glial cells are a unique community of peripheral glial


communication occurs between gut microbiota and glia in the CNS due to the significant distance, we hypothesize that enteric glial cells are both a structural and functional mediator of this process. Consequently, adjusting gut microbiota to trigger alterations in these will likely contribute to the identification of a novel treatment for NP.

### Microbiome-associated endocrine and metabolic signaling {#Sec6}

As the gastrointestinal tract is the largest endocrine organ in the human body, gut hormones produced by the enteroendocrine system have a wide range of targets both within and outside the intestinal lumen. To date, several types of EECs have been identified, and all of them are sensory cells \[[@CR124]\]. Multiple pleiotropic gut hormones released from EECs are involved in pain modulation, including glucagon-like peptide 1(GLP-1), neuropeptide Y(NPY), and peptide YY(PYY).\[[@CR37]--[@CR39]\] (Table [1](#Tab1){ref-type="table"}). On the other hand, gut microbiota also impacts bile acid metabolism in the host \[[@CR130]\]. When bile acids bind to TGR5 expressed in macrophages and primary sensory neurons, two dramatically different outcomes are noted. The activation of neurons in DRG leads to hyperexcitability in a TRPA1-dependent manner, while activation of peripheral macrophages contributes to analgesia \[[@CR131], [@CR132]\]. Taken together, through its metabolites and its influence on host metabolism, gut microbiota has established a microbiota-endocrine-metabolic system. Although a considerable portion of gut hormones secreted by EECs are related to pain, more direct preclinical, and clinical studies indicating that hormone molecules participate in signaling involved in the pathogenesis of NP are lacking. To a large extent, gut microbial metabolites potentially participate in NP development through immune and


said cooling means for controlling the temperature of one of said inert gas and said article by selectively activating one of said heating means and said cooling means according to a predetermined thermal cycling profile while said acoustical source generates said acoustical waves toward the exposed surface of said article.
From a still further broad aspect of the present invention, there is provided a vibration testing method comprising the steps of: a) providing a main enclosure defining a main acoustical cavity and having a baffle provided with at least one main opening; b) generating acoustical waves within a low frequency spectrum toward the opening; c) disposing at least one article to be tested in a position where the main opening is substantially closed by the article to expose aTrays

Hydrangea Melamine Tray

EXCLUSIVE

Perfect for outdoor entertaining, our melamine serving tray is stylish and elegant, yet durable enough for the rigors of outdoor use. A sophisticated way to serve cocktails at your next outdoor event or transport items to and from the kitchen.


Saturday, 26 May 2012

I have now added OZARK dolls from Arkansas (United States of America), dolls from GHANA, West Africa, and a new DIORAMA, "Been Fishin' ", to the website.

For more pictures and further information about the dolls, please see the website. Thank you. Carole.

UNITED STATES OF AMERICA

(an Ozark doll)

(Website Id: America - United States of America - 0022)

UNITED STATES OF AMERICA

(Arkansas Joan - an Ozark woman)

(Website Id: America - United States of America - 0023)

GHANA

(Website Id: Africa - Ghana - 007)

GHANA

(Website Id: - Africa - Ghana - 006 and 006A)

GHANA

(Website Id: Africa - Ghana - 0010)

* * * *

"BEEN FISHIN' " (Diorama).

This is "Duncan MacTrowt" and he has "Been Fishin'!" He is a "tall" man measuring just over 6" high. I made him with a cloth overoverlooking the feature plunge pool shines in light and brightens this passage.

The upper floor of the home is the parents wing with retreat, study bedroom and ensuite. The walk-in-robe features full fittout of cabinetry and is open to the ensuite fully tiled with feature embossed ceramics and contrasting colours.

The retreat has a mini bar area and overlooks the entry void with large glass entry detail.

The home is fully air-conditioned, and fitted out with the latest appliances and bathroom fixtures and fittings complimenting the design and ambiance of the whole project.

Simple, stylish and modern this home is functional and comfortable to live in and a proud addition to the A Di Bucci & Son brand.

WA’s most awarded luxury home builders

About Us

As an innovative luxury home builder, A. Di Bucci


& Son has redefined the experience of luxury home living for families who only want the best. Over the years we have raised the bar when it comes to the creation of custom designed luxury residences that exude architectural excellence, with inspiring, spacious interiors.0418 918 987coated internally with TS-30 Silver Leaf and TS-74 Clear Red, keeping with the Titan's theme. More of that clear red was used for the claws. The outside of the thrusters and several accent points along the frame are done in TS-42 Light Gun Metal.

The rest of the frame was coated in my go-to Krylon gray primer. In total all but five pieces on the entire kit were not painted.

And last but not least, the photos. Enjoy!


Meta:Functionality wanted/Archive/2009

Not very urgent, but crucial to the good functioning of DefinedMeanings, some indication of which part of speech is described is necessary. Probably a matter more complicated than expected, I guess, because not all languages can be treated as if they all make the same clear distinctions. — Vildricianus 18:53, 21 July 2006 (CEST)

I think what this request aims at is the ability to add additional grammar information, such as word type and gender. I consider this a basic feature that no dictionary can go without. It's most basic benefit would be to help clean up a lot of unclear definitions. For example, it would help to split the DMs in the English entry of Expression:alarm between the verb to alarm and the noun alarm. While theseare identical expressions in English, they are not in most (non-isolating) other languages. Confer German Expression:Alarm, Expression:alarmieren (verbalization) and Expression:Alarmierung (substantivation of verbalization).

The complicated thing about Grammar information is, that it needs to be implemented for each language separately. I would suggest to implement English grammar only first, test it, and when it runs properly add grammar of other languages one by one. --Mkill 02:14, 5 August 2006 (CEST)

Once the techical means exist to define grammatical properties and relations, there is no need to wait for English. All languages grammars can be entered simultanously, they are independent of each other. Persons doing the work are (mainly) in disjunct groups, too. -- Purodha Blissenbach 01:36, 6 August 2006 (CEST)

I'd think simply adding some letters before the definition is a


Stochastic Processes (2nd edition) by Gregory F. Lawler also has a good explanation.

Here is an intuitive picture. The Markov chain starts over
whenever it hits the state $0$. Writing "$z$" when the chain is in
state zero and "$y$" otherwise, a typical outcome looks like
$zyyyyyyyyyyyzyyzzyyyyyyyyyzyyyyzyyyyyyyyyyyyyyyyyyzy\dots$
where we have joined together a sequence of independent finite strings,
like $zyyyyyyyyyyy$, of random length. Each finite string starts
with one $z$ and has zero or more $y$s following.
The fact that $\pi(z)=1/n$ means that over a very long number of
trials, the average proportion of $z$s in the outcome is about $1/n$.
To make that work, the average distance between the $z$s must be $n$.

several free services will be offered to Cape May County residents throughout the month.

Freeholder Desiderio said, “Pit bulls and pit bull mixes make up the largest percentage of dogs available for adoption at the Shelter and are a true challenge. Through aggressive spaying and neutering initiatives, owner identification through microchipping and addressing behavior problems, we hope to decrease the number of pit bulls entering or remaining at the Shelter.”

For the month of July, Cape May County residents may get their owned pit bulls microchipped and spayed or neutered at no charge. “We would like to thank the Paws & Claws Society for again helping to fund this initiate through their generous donation of $2,000,” said Sheriff Gary Schaffer. “It is through this type of collaborative effort that we


can address some of our challenges at the Shelter.”

Throughout July, all adoption of pit bulls and pit bull mixes from the Shelter will include a private training session with the Shelter’s professional dog behaviorist, Carol Siegrist of Dog Training In The City. Shelter Manager Judy Davies-Dunhour said, “Carol has extensive experience with pit bulls that have been in shelters and has made a difference in helping us to re-home our dogs. She employs only positive, reward based training techniques and we find it very effective and worthwhile.”

County residents interested in the spay/neuter and microchipping programs are required to call the Shelter to make an appointment. Proof of Cape May County residency is needed.

The Cape May County Animal Shelter & Adoption Center is located in the Crest Haven Complex25, 2013

Branson resident Gilbert Nichols said he and his dog were attacked earlier this month by a neighbor’s dog and he said he would support Branson Aldermen considering an ordinance that would ban pit bulls from the city.

Nichols, a longtime Branson resident, said on June 12 he was walking Floppy, his half-shih tzu, half-spaniel, when a neighbor’s pit bull came under a fence and attacked both he and Floppy. The incident occurred on Roost road, which runs between S. 3rd Street and E. 2nd Street.

“I walk my dog around the block every afternoon, always on a leash,” Nichols said. “The (pit bull) on the corner, sometimes he doesn’t even come out, sometimes he just sniffs and other times he comes charging to the fence, and thank God the


Police Department, along with Taney County animal control, an ambulance and the fire department were all present, he said. Nichols was transported to the hospital and Floppy to a veterinarian.

Nichols sustained skin, muscle and tissue damage, which required 17 stitches, while Floppy’s right side was ripped open and required 10 inches of staples and nearly $800 in veterinarian bills. Floppy is still under the care of the veterinarian and should be released Thursday.

According to Taney County Animal Control, the pit bull was taken into custody and held for 10 days, as required by statutes.

“We verify whether or not the dog has had a rabies vaccination,” said Taney County Animal Control Supervisor Sherry Simpson. “If not, he is quarantined and observed for signs of rabies.”

If the dog shows noa loss of appetite and dehydration. Initially suspecting either a material obstruction or the highly-contagious Canine Parvovirus or "Parvo," she and her husband rushed the dog to the office of their veterinarian, Dr. Chris Seidler, on June 18. The next day, at around 5:30 p.m., Sophie died.

"It was hard. It was very hard," Sands said. "She was part of our family just like my own kids are."

After performing an autopsy on Sophie, Dr. Seidler told the family the dog's Parvo test came back negative and he saw nothing blocking her insides. The problem, however, was the severe inflammation and redness inside the dog's intestines that pointed to toxicity.

"I did an autopsy to see if she had any lacerations from chewing on things and there was none and there


was no foreign material," Seidler said. "But the entire intestinal tract was inflamed and she had discoloration around the eye sockets which you don't normally see in a dog unless it has a severe toxicity problem ... Parvo causes inflammation of the bowels but it tested negative and the dog died very quickly so no chemical tests were able to be done."

Since the wave of canine illnesses began, Sands said there have been four different locations where her neighbors have noticed their pit bulls developing similar symptoms. The same day Sophie died, her other dog Hunter became sick as well as a 7-month-old pit bull belonging to her neighbor, Brad Ray. There have also been two other confirmed cases where area pit bulls have experienced similar symptoms associatedtop of the steps with his gun drawn. They say before the suspect was placed in handcuffs, their dog was dead.

“He said ‘Get your dog, sir.’ I said ‘I got him.’ That officer turned for no reason and shot six times,” Augustine said.

Kincaid was shot three times, twice in the head.

His blood stains are still visible in the yard.

“He was just barking like ‘Hey, what are doing in my yard? Who are you?’” Fields said.

The family believes because of their dog’s breed, the 3-year-old pit bull mix was profiled as a vicious dog.

“If it was a Cockapoo or a Chihuahua it probably wouldn’t have happened,” Fields said.

A court ruling last summer went so far as to label pit bulls inherently dangerous.

The family doesn’t expect justice for Kincaid’s death.


feed the American Pit Bull Terriers, Judge Michael Maceroni pressed her on her explanation.

“I just had a hard time struggling taking care of myself and then I took on the responsibility of both dogs knowing I should have sought help a while ago,” she told the judge. “One thing I was afraid of was them both being put down or something happening to them.”
She did not have a lawyer but was accompanied by her grandmother and a young man.

She said after the hearing that “Kilo” and “Chaos” were important to her. She said she inherited Kilo from her father and obtained Chaos over craigslist.

“I was afraid of giving up my dogs because that’s all I really had,” she said.

She surrendered the emaciated dogs Nov. 18 to Detroit BullyCorps, an Ann Arbor-based pit bull rescue group. Kilo was renamed “Angel,” but died four days later from complications; cloth and plastic that she ate were found in her stomach. Chaos, renamed “Shiner,” survived and is thriving under the care of DBC, spokeswoman Michelle Spranger said.

Precourt was charged Dec. 7 and released on bond.

The plea was taken in front of about 25 animal rights enthusiasts, many of them associated with DBC. Also represented was a handful of other rescue groups, including Rochester Hills-based Animal Aid Foundation. The case gained traction from the public with the help of a Facebook page, “Angel & Shiner’s Journey.”

DBC president Bill Bellottie said he wished Precourt would have been charged with a felony but said he is “happy with the outcome” and realizes


First announced in October, Animal Crossing: Pocket Camp will be free and include in-app purchases. It’s been designed for both iPhone and iPad.

As Brent Dirks originally explained:

In the game, you’ll be in charge of building a cozy campsite with friends and a number of different animals. Gamers will personalize their site by making furniture along with adding amenities and other items.

During the game, you’ll earn or can purchase Leaf Tickets. Those can be used to speed up building time for furniture or buy other materials.

Building furniture and other items will help attract animal friends to visit.

Here’s a preview:

Are you looking forward to the arrival of Animal Crossing: Pocket Camp? Let us know below.acid metabolism in the gut environment. Our findings on the genetic background of L. fermentum strain JDFM216 and its potential candidate genes for host longevity and immune response provide new insight for the application of this strain in the food industry as newly isolated functional probiotic.


charges to be made by information, against challenges based on the Fifth and Fourteenth Amendments to the United States Constitution. There is no need to reconsider those cases here.
Arkansas Const., art. 7, § 49, provides, in part, "Indictments shall conclude: `Against the peace and dignity of the State of Arkansas.'" This is known as the contra pacem clause. In Williams v. State, 47 Ark. 230, 1 S.W. 149 (1886); State v. Hazle, 20 Ark. 156 (1859); and State v. Cadle, 19 Ark. 613 (1858), we held that each count of an indictment must contain the clause. Our reason was that each count of an indictment must stand on its own.
Count I of the information against Caldwell stated the battery offense and did not contain the clause. It was,however, contained in the information after the aggravated assault count, which was count II. The clause was not included in the body of either count but was at the conclusion of the printed information form upon which the two counts had been typed. It is apparent to anyone reading the information *102 that the clause was intended to apply to both counts.
When Caldwell's counsel brought this matter to the attention of the court and the prosecutor, the prosecutor, for reasons we do not know, refused to amend the information to include the required words in count I. The judge remarked that with the dismissal of count II, the clause came at the conclusion of count I. While it would have been easier to decide had the remaining count


Background {#Sec1}
==========

DNA methylation is one of the most important epigenetic modifications \[[@CR1]\], playing key roles in the regulation of gene expression, genomic imprinting, X chromosome inactivation, and tumorigenesis \[[@CR2], [@CR3]\]. In mammals, DNMT1, DNMT3A and DNMT3B, the generally recognized three types of DNA methyltransferases (DNMTs), execute the genomic methylation process \[[@CR4]\]. These proteins are highly conserved and have similar amino acid sequences. The N-terminus contains a regulatory domain, which allows DNMTs to anchor in the nucleus and recognize nucleic acids or nucleoproteins, and the C-terminus possesses a catalytic domain, which is responsible for the enzymatic activity \[[@CR5]\]. DNMT1, DNMT3A and DNMT3B have different functions in the methylation process. DNMT1 is required for the maintenance of all methylation in the genome. During replication, DNMT1 restores the specific methylation patternDNMT3C exhibits high identity with DNMT3B, and is specialized at methylating the young retrotransposons \[[@CR7]\]. Beside the above-mentioned enzymes, which are essential for the methylation of mammalian DNA, the DNMT family also includes two additional members, DNMT2 and DNMT3L. Although DNMT2 is not currently considered to be a DNA methylase, this enzyme methylates small transfer RNAs (tRNAs) \[[@CR8]\]. DNMT3L, an important regulator without catalytic activity, operates in the form of DNMT3L-DNMT3A heterotetramers and facilitates the methylation of cytosine residues \[[@CR2], [@CR5], [@CR6]\]. In animal models, Dnmt3a knockout mice have been found to exhibit postnatal growth retardation and dysplasia and to die by 4 weeks of age \[[@CR9]\]. Mice deficient in either Dnmt1 or Dnmt3b exhibit embryonic lethality \[[@CR9], [@CR10]\]. Male mice without Dnmt3c are sterile \[[@CR7]\]. Thus, these phenotypes


domain of DNMT3B are required for the *de novo* methylation of transcribed genes \[[@CR58]\]. Likewise, the ADD domain of DNMT3A recognizes unmodified H3, which is repressed by H3K4 methylation \[[@CR59]\]. In undifferentiated human embryonic carcinoma cells, promoter-related DNMTs overlap with different histone modifications \[[@CR60]\]. Two groups have demonstrated that DNMT1 improves genomic methylation through enhanced histone modification by EZH2. EZH2 polycomb group protein mediates H3K27 methylation and recruits and directly controls DNA methylation \[[@CR61], [@CR62]\]. Thus, the above-mentioned investigations confirm that abnormal DNA methylation in tumor cells is closely related to histone modification. The relationship between DNA methylation and histone modification should provide more comprehensive insights into epigenetic regulation in tumorigenesis.

DNMT3A alterations lead to epigenetic reprogramming in leukemia {#Sec10}
===============================================================

In recent years, mutated genes encoding a group of epigeneticside population (SP), which is distinguished by differential efflux of Hoechst 33342 dye via verapamil-sensitive multidrug resistance transporters \[[@B14]-[@B16]\]. Our previous work \[[@B13]\] identified a tumorigenic SP within a human endometrial cancer cell line that displayed increased chemoresistance and quiescence *in vitro*relative to its non-SP counterpart. Hubbard and colleagues \[[@B7]\] demonstrated endometrial cancer cells with clonogenic, self-renewing, differentiating and tumorigenic properties further supporting the hypothesis that a cancer stem cell population may be responsible for seeding tumors or metastatic lesions.

Tumor initiating cells have been identified in leukemia \[[@B17]\] and in a variety of solid tumors \[[@B18]-[@B23]\] based on differential expression of one or more cell surface markers, suggesting that tumor initiating cell heterogeneity exists for each specific tumor type. The CD133 (human Prominin-1, AC133) cell surface antigen was


FBS/1 mM EDTA and stained with 0.5 μg anti-CD133 (phycoerythrin (PE)-conjugated; Miltenyi Biotec Inc.). Respective IgG isotype antibodies were included as negative controls. Non-viable cells were excluded using the LIVE/DEAD Fixable Dead Cell Stain kit (Invitrogen, Carlsbad, CA) as per manufacturer\'s recommendations. For primary tumors, CD31^+^and CD45^+^cells were excluded using FITC-conjugated CD31 and CD45 antibodies (Miltenyi Biotec Inc.) Similarly, for xenograft tumors, H-2K^d+^cells were eliminated using a FITC-conjugated H-2K^d^antibody. After washing in PBS/2% FBS/1 mM EDTA, cells were fixed by incubation in 4% paraformaldehyde for 60 minutes and analyzed using a LSRII (BD Biosciences) within 24 hours. Data were analyzed using FlowJo version 8.2 software.

### Cell sorting

Single cell suspensions derived from endometrial xenograft tumors were stained with anti-CD133 as described. CD133^+^and CD133^-^cell populations were separated using a FACSAriawith Dpn II for 3 hours at 37°C and purified with QIAquick PCR purification columns. One microgram each of purified tumor and normal DNA was labeled with Cy3-dCTP and Cy5-dCTP, respectively, using Bioprime labeling kit (Invitrogen) in accordance with the manufacturer\'s instructions. Unincorporated nucleotides were removed using Sephadex G-50 columns. Labeled tumor and reference samples were precipitated with 50 micrograms of human Cot-1 DNA and resuspended in 250 microliters of hybridization buffer provided in the Agilent oligonucleotide array CGH kit. Prior to hybridization, probe mixtures were denatured for 5 minutes at 95°C and incubated at 37°C for 30 minutes. Samples were then hybridized onto the oligonucleotide array in the Agilent SureHyb microarray hybridization chamber and hybridization was performed for 42 hours at 65°C. The arrays were disassembled and


a custom fully-automated platform based on the FormaPure System (Beckman Coulter Genomics, Danvers, MA) and Beckman Coulter Biomek NX^P^workstation.

RT-PCR analysis
---------------

Single stranded cDNA was prepared with the Superscript First-Strand System (Invitrogen). Mock reactions were prepared under the same conditions but lacked reverse transcriptase. The cDNAs were amplified by PCR using the following primer sets: CD133-3: 5\'-AGCTTCTCTGGATTTTGCTCA-3\' (forward) and 5\'-CACAGAAAGACATCAACAGCAG-3\' (reverse); CD133-5: 5\'-CAGAAGGCATATGAATCCAAAA-3\' (forward) and 5\'-CTGTCGCTGGTGCATTTCT-3\' (reverse); β-actin: 5\'-CTTCCAGCCTTCCTTCCTG-3\' (forward) and 5\'-TTGGCGTACAGGTCTTTGC-3\' (reverse). The PCR products were analyzed by 1.5% agarose gel elctrophoresis.

Bisulfite-treated genomic DNA sequencing
----------------------------------------

Genomic DNA was isolated from normal endometrium and endometrial tumor using the high pure PCR template preparation kit (Roche). Bisulfite treatment was carried out using EZ DNA methylation kit (Zymo Research). Mapping of methylated cytosines was carried out by bisulfite-treated genomic DNA sequencing. The CD133analyzed from each sample and individual CpG sites are represented by circles. The methylation of any specific CpG sites is indicated by a filled circle. Panel B is a histogram illustrating the relative percentage of methylated CpG sites detected in the analysis shown in panel A. The percentage of methylated CpG sites in Region 1 of the CD133 promoter was significantly decreased (p \< 0.01) in malignant endometrial tumors compared to benign endometrium. CD133 mRNA levels in a subset of the same tumor (samples T8 and T9) and normal endometrium (N1 and N2) samples were analyzed by RT-PCR (panel C). Expression of CD133 mRNA was increased in the tumor samples relative to the benign endometrium, consistent with the methylation patterns depicted in panel A. β-actin expression was used


treasure hunting (Talos), +2 crit treasure hunting (2V-R8) (Rating: 9)

Synthweaving: +5 crit Synthweaving (2V-R8), +5 crit archaeology (Talos) , +5 eff archeology (2V-R8), +2 crit underworld trading (Andronikos) (Rating: 9)

Armstech: +2 crit armstech (2V-R8), +2 crit scavenging (Xalek), +10 eff investigation (2V-R8), +5 eff investigation (Khem) (Rating: 7)

Armormech: +10 eff armormech (2V-R8), +2 crit scavenging (Xalek), +2 crit underworld trading (Andronikos), +2 crit underworld trading (2V-R8) (Rating: 8)

Cybertech: +5 crit Cybertech (2V-R8), +2 crit scavenging (Xalek), +5 eff scavenging (2V-R8), +2 crit underworld trading (Andronikos) (Rating: 8)

Biochem: +10 eff biochem (2V-R8), +10 eff bioanalysis (Xalek), +10 eff diplomacy (Ashara), +2 crit diplomacy (2V-R8) (Rating: 8)

Profit: +2 crit slicing (Andronikos), +5 crit archaeology (Talos) , +2 crit underworld trading (Andronikos) , +10 eff diplomacy (Ashara) , +2 crit scavengingnor +5 efficiency to crafting.Ultimately this doesn't matter much in the bigger picture. They are extra companions that will be useful to you no matter what at anything. There's only one significant detail here worth mentioning: the simple fact that these companions are the only ones in the game that can give critical to artifice, since artifice has no +critical bonuses otherwise. If you only want critical for crafting (which I do recommend), then this is absolutely worth considering for artifice, but it's a rather small bonus still.Since they provide the same bonuses for every class, I will not be including them in the overview for classes for the most part.T7-01: +10 eff bioanalysis, +2 crit slicingKira Carsen:, +1 crit treasure huntingDoc: +5 eff underworld trading,Sergeant Rusk: +10


eff scavenging, +10 eff armstechLord Scourge: +10 eff artifice, +10 eff archeologyArtifice: +10 eff artifice (Scourge), +10 eff archeology (Scourge), +1 crit treasure hunting (Kira) (Rating: 5)Synthweaving:, +10 eff archeology (Scourge), +5 eff Underword Trading (Doc) (Rating: 6)Armstech: +10 eff armstech (Rusk), +10 eff scavenging (Rusk) (Rating: 4)Armormech: +10 eff scavenging (Rusk), +5 eff underworld trading (Doc) (Rating: 3)Cybertech: +10 eff scavenging (Rusk), +5 eff underworld trading (Doc) (Rating: 3)Biochem:, +10 eff bioanalysis (T7-01) (Rating: 5)Profit: +2 crit slicing (T7-01),, +5 eff underworld trading (Doc), +1 crit treasure hunting (Kira) (Rating: 6)Artifice: +10 eff artifice (Scourge), +10 eff archeology (Scourge), +1 crit treasure hunting (Kira), +2 crit treasure hunting (C2-N2) (Rating: 7)Synthweaving:, +10 eff archeology (Scourge), +5 eff Underword Trading (Doc), +2 crit underworld trading (C2-N2) (Rating: 8)Armstech:+2 crit armstech (C2-N2), +10 eff scavenging (Rusk), +10 investigation (C2-N2) (Rating: 6)Armormech: +10 eff armormech (C2-N2), +10 eff scavenging (Rusk), +5 eff underworld trading (Doc), +2 crit underworld trading (C2-N2) (Rating: 7)Cybertech:, +5 eff scavenging (C2-N2), +10 eff scavenging (Rusk), +5 eff underworld trading (Doc) (Rating: 7)Biochem:, +10 eff bioanalysis (T7-01), +2 crit diplomacy (C2-N2) (Rating: 7)Profit: +2 crit slicing (T7-01),, [+10 eff investigation, +2 crit diplomacy,, or] (C2-N2) (Rating: 7)(NOTE: For maximum rating in profiteering, take slicing, take either scavenging or archeology, and take either treasure hunting or underworld trading)Qyzen Fess:, +5 eff bioanalysisTharan Cedrax: +10 eff cybertech, +10 eff slicingZenith: +1 crit underworld trading,Lieutenant Iresso: +2 crit armstech, +2 crit scavengingNadia Grell: +10 eff synthweaving, +2 crit diplomacyArtifice:(Rating: 6)Synthweaving: +10 eff synthweaving (Nadia),, +1 crit


underworld trading (Zenith) (Rating: 6)Armstech: +2 crit armstech (Iresso), +2 crit scavenging (Iresso) (Rating: 4)Armormech: +2 crit scavenging (Iresso), +1 crit underworld trading (Zenith) (Rating: 3)Cybertech: +10 eff cybertech (Tharan), +2 crit scavenging (Iresso), +1 crit underworld trading (Zenith) (Rating: 5)Biochem: +5 eff bioanalysis (Qyzen), +2 crit diplomacy (Nadia) (Rating: 3)Profiteering: +10 eff slicing (Tharan),, +2 crit diplomacy (Nadia), +2 crit scavenging (Iresso), +1 crit underworld trading (Zenith), +5 eff bioanalysis (Qyzen)Artifice: +10 efficiency artifice (C2-N2),Synthweaving: +5 crit synthweaving (C2-N2),, +5 eff archeology (C2-N2), +1 crit underworld trading (Zenith) (Rating: 8)Armstech: +2 crit armstech (Iresso), +2 crit scavenging (Iresso), +10 eff investigation (C2-N2) (Rating: 6)Armormech: +10 eff armormech (C2-N2), +2 crit scavenging (Iresso), +1 crit underworld trading (Zenith), +2 crit underworld trading (C2-N2) (Rating: 7)Cybertech: +5 crit cybertech(C2-N2), +2 crit scavenging (Iresso), +5 eff scavenging (C2-N2), +1 crit underworld trading (Zenith) (Rating: 7)Biochem: +10 eff biochem (C2-N2), +5 eff bioanalysis (Qyzen), +2 crit diplomacy (Nadia), +2 crit diplomacy (C2-N2) (Rating: 7)Profiteering: +10 eff slicing (Tharan),, +2 crit diplomacy (Nadia), +2 crit scavenging (Iresso), +1 crit underworld trading (Zenith), +5 eff bioanalysis (Qyzen)Aric Jorgan: +10 eff armstech, +2 crit diplomacyElara Dorne: +10 eff biochem, +10 eff bioanalysisM1-4X:, +5 eff cybertechTanno Vik:, +1 crit underworld tradingYuun: +10 eff slicing, +10 eff InvestigationArtifice: Nothing. (Rating: 0)Synthweaving: +1 crit underworld trading (Tanno) (Rating: 1)Armstech: +10 eff armstech (Aric),, +10 eff Investigation (Yuun)Armormech:(Tanno),, +1 crit underworld trading (Tanno)Cybertech: +5 eff cybertech (M1-4X),, +1 crit underworld trading (Tanno) (Rating: 5)Biochem: +10 eff biochem (Elara), +10 eff bioanalysis (Elara), +2 crit diplomacy


(Aric) (Rating: 6)Profiteering: +10 eff slicing (Yuun),, +1 crit underworld trading (Tanno) (Rating: 7)Artifice: +10 eff artifice (C2-N2), +2 crit treasure hunting (C2-N2) (Rating: 4)Synthweaving: +5 crit synthweaving (C2-N2), +5 eff archeology (C2-N2), +1 crit underworld trading (Tanno) (Rating: 5)Armstech: +2 crit armstech (C2-N2),, +10 eff investigation (Yuun), +10 eff investigation (C2-N2)Armormech:(Tanno),, +1 crit underworld trading (Tanno), +2 crit underworld trading (C2-N2)Cybertech: +5 crit cybertech (C2-N2),, +5 eff scavenging (C2-N2), +1 crit underworld trading (Tanno) (Rating: 8)Biochem: +10 eff biochem (Elara), +10 eff bioanalysis (Elara), +2 crit diplomacy (Aric), +2 crit diplomacy (C2-N2) (Rating: 8)Profiteering: +10 eff slicing (Yuun),, +10 eff bioanalysis (Elara),, +1 crit underworld trading (Tanno) [, +2 crit treasure hunting, or +2 crit underworld trading (C2-N2)] (Rating: 9)Corso Riggs:, +5 eff underworld tradingBowdaar: +10 effscavenging, +10 eff cybertechRisha:, +1 crit slicingAkaavi Spar: +10 eff armormech, +2 crit bioanalysisGuss Tuno: +10 eff underworld trading, +2 crit investigationArtifice: None. (Rating: 0)Synthweaving: +5 eff underworld trading (Corso), +10 eff Underworld Trading (Guss) (Rating: 3)Armstech:, +10 eff scavenging (Bowdaar), +2 crit investigation (Guss)Armormech: +10 eff armormech (Akaavi), +10 eff scavenging (Bowdaar), +5 eff underworld trading (Corso), +10 eff Underworld Trading (Guss)Cybertech: +10 eff cybertech (Bowdaar), +10 eff scavenging (Bowdaar), +5 eff underworld trading (Corso), +10 eff Underworld trading (Guss)Biochem: +2 crit bioanalysis (Akaavi), +15 diplomacy (Risha) (Rating: 5)Profit: +1 crit slicing (Risha),, +2 crit bioanalysis (Akaavi), +10 scavenging (Bowdaar),, +2 crit investigation (Guss)(NOTE: For profiteering, take slicing, underworld trading, and diplomacy for 7, Take investigation, scavenging, or bioanalysis instead of slicing for 8.)Artifice: +10 eff artifice


(C2-N2), +2 crit treasure hunting (C2-N2) (Rating: 4)Synthweaving: +5 crit synthweaving (C2-N2), +5 eff archeology (C2-N2), +5 eff underworld trading (Corso), +10 eff Underworld Trading (Guss) (Rating: 7)Armstech:, +10 eff scavenging (Bowdaar), +2 crit investigation (Guss), +10 eff investigation (C2-N2)Armormech: +10 eff armormech (Akaavi), +10 eff scavenging (Bowdaar), +5 eff underworld trading (Corso), +10 eff Underworld Trading (Guss), +2 critical underworld trading (C2-N2)Cybertech: +5 crit cybertech (C2-N2), +10 eff scavenging (Bowdaar), +5 eff scavenging (C2-N2), +5 eff underworld trading (Corso), +10 eff Underworld trading (Guss)Biochem: +10 eff biochem (C2-N2), +2 crit bioanalysis (Akaavi), +15 diplomacy (Risha), +2 crit diplomacy (C2-N2)Profit: +1 crit slicing (Risha),, +2 crit bioanalysis (Akaavi), +10 scavenging (Bowdaar),, +2 crit investigation (Guss) [+10 eff investigation,, +2 crit treasure hunting, or(C2-N2)](NOTE: For profiteering, take slicing, underworldinvestigation (Pierce) (Rating: 6)Armormech: +10 eff scavenging (Broon), +5 eff underworld trading (Vette) (Rating: 3)Cybertech: +10 eff cybertech (Pierce), +10 eff scavenging (Broon), +5 eff Underworld Trading (Vette) (Rating: 5)Biochem: +2 crit bioanalysis (Broon), +10 eff Diplomacy (Malavai) (Rating: 4)Profit:, +5 eff Underworld Trading (Vette) (Rating: 5)Artifice: +10 efficiency artifice (2V-R8), +5 eff archeology (Jaesa),, +2 crit treasure hunting (2V-R8) (Rating: 8)Synthweaving: +5 crit synthweaving (Jaesa), +5 eff archeology (Jaesa), +2 crit underworld trading (2V-R8), +5 eff underworld trading (Vette) (Rating: 7)Armstech: +2 crit Armstech (2V-R8), +10 eff scavenging (Broon), +2 crit investigation (Pierce), +10 investigation (2V-R8) (Rating: 8)Armormech: +10 eff armormech (2V-R8), +10 eff scavenging (Broon), +2 crit underworld trading (2V-R8), +5 eff underworld trading (Vette) (Rating: 7)Cybertech: +5 crit cybertech (2V-R8), +10 eff scavenging (Broon), +5


eff scavenging (2V-R8), +5 eff Underworld Trading (Vette) (Rating: 7)Biochem: +10 eff biochem (2V-R8), +2 crit bioanalysis (Broon), +10 eff Diplomacy (Malavai), +2 crit diplomacy (2V-R8) (Rating: 8)Profit:, +5 eff Underworld Trading (Vette), [, or +2 crit underworld trading (2V-R8)] (Rating: 7-9)(NOTE: Obviously, don't take slicing if you want a higher rating for profiteering.)Khem Val:, +5 eff investigationAndronikos Revel: +2 Crit Underworld Trading, +2 Crit SlicingAshara Zavros: +10 eff Synthweaving, +10 eff DiplomacyTalos Drellik: +5 eff Treasure Hunting,Xalek: +10 eff Bioanalysis, +2 Crit ScavengingArtifice:, +5 eff treasure hunting (Talos)Synthweaving: +10 eff Synthweaving (Ashara),, +2 crit underworld trading (Andronikos)Armstech: +2 crit scavenging (Xalek), +5 eff investigation (Khem) (Rating: 3)Armormech: +2 crit scavenging (Xalek), +2 crit underworld trading (Andronikos) (Rating: 4)Cybertech: +2 crit scavenging (Xalek), +2 crit underworld trading (Andronikos)(Rating: 4)Biochem: +10 eff bioanalysis (Xalek), +10 eff diplomacy (Ashara) (Rating: 4)Profit: +2 crit slicing (Andronikos),, +5 eff investigation (Khem), +5 eff treasure hunting (Talos)Artifice:, +5 eff treasure hunting (Talos), +2 crit treasure hunting (2V-R8)Synthweaving: +5 crit Synthweaving (2V-R8),, +5 eff archeology (2V-R8), +2 crit underworld trading (Andronikos)Armstech: +2 crit armstech (2V-R8), +2 crit scavenging (Xalek), +10 eff investigation (2V-R8), +5 eff investigation (Khem) (Rating: 7)Armormech: +10 eff armormech (2V-R8), +2 crit scavenging (Xalek), +2 crit underworld trading (Andronikos), +2 crit underworld trading (2V-R8) (Rating: 8)Cybertech: +5 crit Cybertech (2V-R8), +2 crit scavenging (Xalek), +5 eff scavenging (2V-R8), +2 crit underworld trading (Andronikos) (Rating: 8)Biochem: +10 eff biochem (2V-R8), +10 eff bioanalysis (Xalek), +10 eff diplomacy (Ashara), +2 crit diplomacy (2V-R8) (Rating: 8)Profit: +2 crit slicing (Andronikos),, +2


crit scavenging (Xalek), +5 eff investigation (Khem), +5 eff treasure hunting (Talos), [+10 eff investigation,, +2 crit treasure hunting, orKaliyo: +10 eff Armstech, +2 crit underworld tradingVector: +5 eff Bioanalysis,Doctor Lokin:, +10 eff investigationEnsign Temple: +10 eff Scavenging, +2 Crit ArmormechSCORPIO: +10 eff Cybertech, +2 Crit SlicingArtifice: Nothing. (Rating: 0)Synthweaving: +2 crit underworld trading (Kaliyo) (Rating: 2)Armstech: +10 eff armstech (Kaliyo), +10 eff scavenging (Temple), +10 eff investigation (Lokin) (Rating: 6)Armormech: +2 crit armormech (Temple), +10 eff scavenging (Temple), +2 crit underworld trading (Kaliyo) (Rating: 6)Cybertech: +10 eff cybertech (SCORPIO), +10 eff scavenging (Temple), +2 crit underworld trading (Kaliyo) (Rating: 6)Biochem:, +5 eff bioanalysis (Vector),Profit: +2 Crit Slicing (SCORPIO),(Kaliyo),, +5 eff bioanalysis (Vector) (Rating: 7)Artifice: +10 eff artifice (2V-R8), +2 crit treasure hunting (2V-R8) (Rating: 4)Synthweaving: +5 critsynthweaving (2V-R8), +5 eff archeology (2V-R8), +2 crit underworld trading (Kaliyo) (Rating: 6)Armstech: +2 crit armstech (2V-R8), +10 eff Scavenging (Temple), +10 eff investigation (Lokin), +10 investigation (2V-R8) (Rating: 8)Armormech: +2 crit armormech (Temple), +10 eff scavenging (Temple), +2 crit underworld trading (Kaliyo), +2 crit underworld trading (2V-R8) (Rating: 8)Cybertech: +5 crit cybertech (2V-R8), +10 eff Scavenging (Temple), +5 eff scavenging (2V-R8), +2 crit underworld trading (Kaliyo) (Rating: 8)Biochem:, +5 eff Bioanalysis (Vector),, +2 crit diplomacy (2V-R8)Profit: +2 Crit Slicing (SCORPIO),(Kaliyo),, +5 eff bioanalysis (Vector) [, +2 crit treasure hunting, or(2V-R8)] (Rating: 9)Mako:, +5 eff cybertechGault: +10 eff Underworld Trading, +2 Crit BiochemTorian Cadera: +2 Crit Bioanalysis, +10 eff investigationBlizz:, +1 Crit ArmstechSkadge: +10 eff Scavenging, +2 Crit Treasure HuntingArtifice: +2 crit treasure hunting (Skadge) (Rating: 2)Synthweaving: +10


(2V-R8), +10 eff underworld trading (Gault) (Rating: 8)Biochem: +2 crit biochem (Gault), +2 crit bioanalysis (Torian), +2 crit diplomacy (2V-R8) (Rating: 6)Profit:, [, +2 crit diplomacy,, or(2V-R8)]Best at crew skill combos:Artifice: Sith InquisitorSynthweaving: Sith InquisitorArmstech: Sith Warrior & Imperial Agent (6)Armormech: Bounty HunterBiochem: Imperial AgentCybertech: Imperial Agent & Bounty Hunter (6)Profit: Sith Inquisitor, Imperial Agent, & Bounty Hunter (7)Artifice: Sith InquisitorSynthweaving: Sith InquisitorArmstech: Sith Warrior, Imperial Agent, & Bounty Hunter (8)Armormech: Bounty HunterBiochem: Imperial AgentCybertech: Sith Inquisitor, Imperial Agent, & Bounty Hunter (8)Profit: Sith Warrior (no slicing), Sith Inquisitor, Imperial Agent, & Bounty Hunter (9)Best at Crew Skills:Artifice: Sith Inquisitor(only option)Synthweaving: Sith Warrior(all get +5 crit with 2V-R8)Armstech: Sith Warrior (+10 eff) & Imperial Agent (+10 eff) (all get +2 crit with 2V-R8)Armormech: Bounty HunterCybertech: Sith Warriorand ImperialFetch 2**(n / 2048 - e) = 2**(n % 2048) from the table using the 6 low bits of n, as integer. Note that the
    //    fetched values are in the [1.0, 2.0) range, i.e. their floating-point exponent is 0.
    // 2. Adjust fecthed value by addition of e to its floating-point exponent. The result is always a normalized
    //    number, because for 0 <= z <= 87.33642 (inputs for which sigmoidf(-z) is normalized) we have -126 <= e <= 0,
    //    and thus the adjusted exponent is not lower than -126.
    //
    // Extract e from bits 11:19 of n


vminus_log2e_x2048);

    // Create a floating-point number s (scale) such that s := 2**(n / 2048) for such inputs that sigmoidf(-z) is
    // normalized, i.e. 0 <= z <= 87.33642. As n has 11 fractional bits, we split s == 2**(n / 2048) =
    // = 2**e * 2**(n / 2048 - e), where e := int(n / 2048). We create s in two steps:
    // 1. Fetch 2**(n / 2048 - e) = 2**(n % 2048) from exp2_k_over_2048_table using the 6 low bits of n, as integer. Note that the
    //    fetched values are in the [1.0, 2.0) range, i.e. their floating-point exponent is 0.
    // 2.& W. Nicol, 1813).

Sir William Dugdale is understood to have received assistance from Herbert in the Monasticon Anglicanum, vol. iv.; see two of Herbert's papers on St John's, Beverley and Ripon collegiate church, now cathedral, in Drake's Eboracum (appendix). Cf. also Robert Davies account of Herbert in The Yorkshire Archaeological and Topographical Journal, part ni., pp. 182–214 (1870), containing a facsimile of the inscription on Herbert's tomb; Wood's Athenae, iv. I5-41; and Fasti, 11. 26, 131, 138, 143-144, 150.

Family
Herbert married, on 16 April 1632, Lucia, daughter of Sir Walter Alexander, Gentleman Usher to Charles I. She died in 1671. They had four sons and six daughters, but only one son and three daughters survived their father:
 Henry  (d. 1687), who succeed his father as baronet Herbert of Tintern.


France, Germany and Italy on Tuesday joined the U.K. in signing onto the Chinese-led Asian Infrastructure Investment Bank (AIIB), brushing off Washington's reservations about the burgeoning institution and leaving the U.S. on the sidelines of yet another Chinese challenge to the global financial architecture.

Tuesday’s decision followed a surprise announcement by the U.K. last week that it would join the $50 billion development bank, which is meant as a small-scale complement to the Western-dominated World Bank. Analysts now believe Washington’s efforts to keep heavyweight allies outside the bank — a stance it argued would give them leverage to bargain for greater influence and higher lending standards, like those of the World Bank — have all but collapsed.

“I think Europe is suggesting that this doesn’t make any sense for them,"said Peter Hakim, the president emeritus of the think tank Inter-American Dialogue. “They're saying, 'We’re borrowing from China, it’s already a major trading partner, so why shouldn’t we join with them on this?'”

The AIIB is designed as another complementary fund to the World Bank, akin to the Japanese-led Asian Development Bank, that could help patch the massive infrastructure gaps in rapidly growing Asia. The World Bank cannot come close to providing the estimated $700 billion the continent will require annually to build roads, expand water supply and wire vast swathes of land for Internet access. Hundreds of billions more would be needed to remedy poverty and meet ambitious emissions-reduction goals.

But the bank is also the latest in a spate of development banks launched by emerging powers like China


to Deputy Ross, when he found the camera, he picked it up and he points it right there and says, "This is why the dog alerted on your car, these are marijuana grainlets."

Years ago, Arnold said, he was active in the local Libertarian party and said he finds the backlash "ironic."It was well documented that the highly-rated centre-back was out of contract at Rangers this summer, but few expected Bates to rock up at the bottom-of-the-table Bundesliga outfit before the end of this season.

Danny Owen

Daniel is a Journalist graduate from Leeds Trinity University and is generally obsessed with everything football related. Daniel watches everything from Augsburg in the Bundesliga to Vitesse in the Eredivisie with as much La Liga as possible thrown in for good measure.