IRQ_TYPE_EDGE_BOTH:
		*rtsr |= mask;
		*ftsr |= mask;
		break;
	default:
		return -EINVAL;
	}

	return 0;
}

static int stm32_irq_set_type(struct irq_data *d, unsigned int type)
{
	struct irq_chip_generic *gc = irq_data_get_irq_chip_data(d);
	struct stm32_exti_chip_data *chip_data = gc->private;
	const struct stm32_exti_bank *stm32_bank = chip_data->reg_bank;
	u32 rtsr, ftsr;
	int err;

	irq_gc_lock(gc);

	rtsr = irq_reg_readl(gc, stm32_bank->rtsr_ofst);
	ftsr = irq_reg_readl(gc, stm32_bank->ftsr_ofst);

	err = stm32_exti_set_type(d, type, &rtsr, &ftsr);
	if (err) {
		irq_gc_unlock(gc);
		return err;
	}

	irq_reg_writel(gc, rtsr, stm32_bank->rtsr_ofst);
	irq_reg_writel(gc, ftsr, stm32_bank->ftsr_ofst);

	irq_gc_unlock(gc);

	return 0;
}

static void stm32_chip_suspend(struct stm32_exti_chip_data *chip_data,
			       u32 wake_active)
{
	const struct stm32_exti_bank *stm32_bank = chip_data->reg_bank;
	void __iomem *base = chip_data->host_data->base;

	/* save rtsr, ftsr registers */
	chip_data->rtsr_cache = readl_relaxed(base + stm32_bank->rtsr_ofst);
	chip_data->ftsr_cache = readl_relaxed(base + stm32_bank->ftsr_ofst);

	writel_relaxed(wake_active, base + stm32_bank->imr_ofst);
}

static void stm32_chip_resume(struct stm32_exti_chip_data *chip_data,
			      u32 mask_cache)
{
	const struct stm32_exti_bank *stm32_bank = chip_data->reg_bank;
	void __iomem *base = chip_data->host_data->base;

	/* restore rtsr, ftsr, registers */
	writel_relaxed(chip_data->rtsr_cache, base + stm32_bank->rtsr_ofst);
	writel_relaxed(chip_data->ftsr_cache, base + stm32_bank->ftsr_ofst);

	writel_relaxed(mask_cache, base + stm32_bank->imr_ofst);
}

static void stm32_irq_suspend(struct irq_chip_generic *gc)
{
	struct stm32_exti_chip_data *chip_data = gc->private;

	irq_gc_lock(gc);
	stm32_chip_suspend(chip_data,so after hot reboot we should
	 * clear registers to avoid residue
	 */
	writel_relaxed(0, base + stm32_bank->imr_ofst);
	writel_relaxed(0, base + stm32_bank->emr_ofst);
	writel_relaxed(0, base + stm32_bank->rtsr_ofst);
	writel_relaxed(0, base + stm32_bank->ftsr_ofst);
	writel_relaxed(~0UL, base + stm32_bank->rpr_ofst);
	if (stm32_bank->fpr_ofst != UNDEF_REG)
		writel_relaxed(~0UL, base + stm32_bank->fpr_ofst);

	pr_info("%s: bank%d, External IRQs available:%#x\n",
		node->full_name, bank_idx, irqs_mask);

	return chip_data;
}

static int __init stm32_exti_init(const struct stm32_exti_drv_data *drv_data,
				  struct device_node *node)
{
	struct stm32_exti_host_data *host_data;
	unsigned int clr = IRQ_NOREQUEST | IRQ_NOPROBE | IRQ_NOAUTOEN;
	int nr_irqs, ret, i;
	struct irq_chip_generic *gc;
	struct irq_domain *domain;

	host_data = stm32_exti_host_init(drv_data, node);
	if (!host_data) {
		ret = -ENOMEM;
		goto out_free_mem;
	}

	domain = irq_domain_add_linear(node, drv_data->bank_nr * IRQS_PER_BANK,
				       &irq_exti_domain_ops, NULL);
	if (!domain) {
		pr_err("%s: Could not register interrupt domain.\n",
		       node->name);
		ret = -ENOMEM;
		goto out_unmap;
	}

	ret = irq_alloc_domain_generic_chips(domain, IRQS_PER_BANK, 1, "exti",
					     handle_edge_irq, clr, 0, 0);
	if (ret) {
		pr_err("%pOF: Could not allocate generic interrupt chip.\n",


3GPP TS 45.005 V9.5.0), the selectivity requirement will be about 84 dB. The ADC Spurious Free Dynamic Range (SFDR) needs to be larger than 90 dBFS, which is a very high requirement. For outband blocking, if we consider a co-location situation in which the Continuous Wave (CW) blocking level is 16 dBm, in order to make the sensitivity degrade less than 0.1 dB for a Global System Mobile (GSM) system, the selectivity should be larger than 150 dB which is also a very high requirement. Filters need to contribute a lot to rejection in the positions where large blocking signals occurs and can not be efficiently suppressed by the Rx circuit. The high requirement for these components makes the product expensive and bulky.in order to survive. Above all, they had no intention of letting the urban working class operate as an independent class force – ‘workers democracy’ was ruled out and crushed from the beginning. That is the one policy that the Chinese leadership has followed through all its twists and turns from the Great Leap Forward to NEP to this day, as Zhao Ziang found to his cost.

Even in 2005, around 40% of industry is in state hands. And the vast bulk of agriculture is controlled by communes and not by modern capitalist farmers or multinational agro companies. At the same time, most of the new industry, particularly those sectors making consumer goods or hi-tech products are privately owned, usually through joint ventures with foreign corporations (that provide the


-87622646051 + 2542?
-87622643509
Add 257041283366 and -0.54.
257041283365.46
24891493+32165.2
24923658.2
What is the distance between 28845287 and 269.14?
28845017.86
Work out -833800 + 1.2971282.
-833798.7028718
What is 0.0659785744 less than -0.26534?
-0.3313185744
Add -0.2 and 109.524281749.
109.324281749
What is -0.4 + -6247870698525?
-6247870698525.4
Calculate -30.7582269126 + -0.1.
-30.8582269126
What is -732 take away 3.6041991?
-735.6041991
Subtract 3.4318 from 1544890205.
1544890201.5682
What is 145258117 plus -507?
145257610
What is 0.1 minus 9658.750693?
-9658.650693
Put together 92 and 262597318.
262597410
What is 0.22 - -22401.666179942?
22401.886179942
Put together 4.84982 and -216.159.
-211.30918
What is 34544517 less than -97437.87?
-34641954.87
Sum 32354984169 and -2.06.
32354984166.94
What is -7122739567627 minus 4?
-7122739567631
What is 0.23 minus -113231.90374607?
113232.13374607
What is -0.2 minus 548150435445?
-548150435445.2
What is -0.0615611308 less than -4.436?
-4.3744388692
Calculate 0.45 - 18413.1756267.
-18412.7256267
What is 0.4 - -0.92340672163075?
1.32340672163075
Calculate 94.346319 - -13.85.
108.196319
9335120.2 - -19.153
9335139.353
15.7 - 24001759
-24001743.3
1.773 + 3.53820816
5.31120816
22+-792641805878
-792641805856
What is 0.011407 + -27.05371?
-27.042303
What is -2605512224 minus 0.481?
-2605512224.481
Subtract 17157.7 from 12.3635.
-17145.3365
What is -2779 + -9621236?
-9624015
1.566+-162.168023
-160.602023
What is 16379001550 + 172?
16379001722
What is 13 minus -1085291525.279?
1085291538.279
-0.10589023 + -8.717684
-8.82357423
What is 6083021Joy Reid and Lawrence O’Donnell, host of ‘The Last Word’ on MSNBC, discuss what he calls the ‘cesspool of sexual harassment’ at Fox and the latest accusations against Bill O’Reilly.


would be mortified times one million.

As I’m struggling with the sleeves, trying to get my shirt back on… I see a pair of feet stroll past me. I didn’t see one of those red tipped seeing eye sticks, so this person was clearly a seeing person. A witness. Ok. Carry on.

My sleeves were all wonky, I couldn’t button my shirt inside out. I was a hot mess… so I had to take my shirt off (again!) invert the spazzy sleeves and put my shirt back on. That’s twice that I’ve taken my top off… Enough!

I never did look up from the ground. I never did blush. I did, however, want to dig a whole through the concrete and tunnel home instead of putting my shirt back on andflour, cornmeal, sugars, baking powder, baking soda and salt. In a small bowl, carefully whisk together eggs, buttermilk, lemon zest and butter. Add the wet ingredients, all at once, to the dry ingredients and fold together with a spatula. Fold until very few lumps remain. Pour batter into the prepared buttered pan and place in the oven.

While the cake bakes, whisk together powdered sugar and lemon juice for the glaze. Set aside.

Bake for 30 minutes or until a skewer inserted into the center of the cake comes out clean. Remove from the oven and let cool for 10 minutes. Use a skewer or the tines of a fork to poke holes in the bake. Sporadic holes here and there will do. Pour over the glaze, spread evenly and


I had just pulled into a parking lot and was able to park…and the bee was a tiny little sweat bee. Did sting me, but got him out. How does a bee manage to do that? (And my car had the a/c running and the windows closed!)

Glad you survived. The lemon cake I will try! It sounds lovely! Do you think instead of the all-purpose flour I could substitute something else to make it gluten-free? It would be fine for me, but I have many close family members who can’t tolerate gluten at all. Thanks!

Oh MY. This made me laugh – very loudly. I wondered what I would have done in your shoes – maybe take my top off, but definitely swear like a fishmonger’s wife until IQ:

Karaf client failes to connect to a server under linux

I am trying to access an opendaylight server running on Linux in a back round process.
I am running a distribution-karaf-0.2.1-Helium-SR1.
From what I understand in case you are trying to connect from the same machine all you need to do is run
./client and the connection will be done.
However all I get is :

[root@d20-srv-81-32 bin]# ./client
  Logging in as karaf
  258 [pool-2-thread-2] WARN org.apache.sshd.client.keyverifier.AcceptAllServerKeyVerifier - Server at /0.0.0.0:8101 presented unverified key:
  [root@d20-srv-81-32 bin]#

When I to try to connect using a simple ssh:
ssh -o UserKnownHostsFile=/dev/null -o StrictHostKeyChecking=no -p 8101 karaf@localhost
the operation is successful.
Has any one encountered the issue?
more info ./client -v result
[root@d20-srv-81-32 bin]# ./client -v
23 [main] INFO org.apache.sshd.common.util.SecurityUtils - BouncyCastle not registered, using the default JCE provider
207 [pool-2-thread-1] INFO


opendaylight download page there are two versions. one compressed as a zip and the other as tar.gz. from what i found there are system differences between them the zip is for windows and the tar for Linux.
when i deployed the tar version on Linux the issue did not reproduce.

matter or sediment. Dissolved concentrations of REEs in these environments are therefore often very low, ranging from 2.9 to 714 ng L^--1^ for Ce and 0.04--7 ng L^--1^ for Lu.^[@ref10]^

Some studies on REE toxicity in freshwater organisms concluded that even if REEs are a group of metals with similar chemical properties, toxicity differences have been observed between heavy REEs (HREEs) and light REEs (LREEs).^[@ref11],[@ref12]^ Among the four most abundant REEs, yttrium (Y) is the only one classified as a HREE. Nevertheless, to our knowledge, in comparison with lanthanum (La), cerium (Ce), and neodymium (Nd), Y toxicity has received less attention so far. Yet, Y is needed in many high-technology applications such as optical fiber and light-emitting diodes.^[@ref3]^ Furthermore, a recent study reported cytotoxicity linked to Y.^[@ref13]^

Animal sensitivity toward


Want to keep in the loop on the latest happenings at Chabad House Jewish Community Center. Subscribe to our mailing list below. We'll send you information that is fresh, relevant, and important to you and our local community.

>>> Rules for the 8 lights 8 nights Chanukah contest.
Each night we raffle off a free $25 gift card to a local store!
HERE'S HOW TO WIN:
1) Light your menorah, and take a photo (selfie) with you and the lit Menorah.
2) Get as many people (family, friends, neighbors...) in the photo as possible. Each person is another chance to win!
3) Post the photo to facebook.
4) "Like" Chabad (at: www.Facebook.com/MyChabad.)
5) Tag "Chabad House Jewish Center," "Rabbi Mendy Kivman" and/or "Rochy Kivman."
6) You're entered!
7) Each afternoon, we'll make a raffle for the entries of" They're here." "They're shooting." "There's nothing we can do except stick up for Mark." "Standing by him." "You look like a star out there." "I'm enjoying all the attention." "Don't get used to everybody taking orders." "I was hoping for a sequel." "Some of us are working stiffs." "Measles in 4." "Later." "Mr. Schoenberger's in sinus rhythm." "BP's 110/70, pulse is 72, reps are" "Resps" " Sorry." " Should I start over?" " Sure." "Next time you can just keep going." "Well, his cardiogram is normal." "His shortness of breath was resolved with oxygen." "He may have had indigestion." "Today was all-you-can-eat at my favorite Mexican place." "Do you have history of heart disease?" "No." "My relatives generally prefer cancer." " Do you smoke?" " Not cigarettes."


" The old guy?" " Yeah." "They're a pair." "May-Decembers." "Never hold up." "You guys talking about the filmmakers?" "We don't trust them." "They're bloodsuckers." "Should you be doing that in front of the camera?" " Is that on?" " Doug, Mark!" "Got a double trauma!" "Help my brother." "Fourteen-year-old, blunt trauma from baseball bats." " Bats?" " They jumped him." "Pulse 130." "BP 100/60." "We got a 30-year-old victim of a 15-foot-fall onto a concrete surface." "Brief loss of consciousness at scene, cleared en route." "Now alert and oriented." "Occipital hematoma." "BP 60 palp." "Pulse 120." "Flaccid paralysis in all four extremities with loss of sensation." "Call Neurology and get X-ray down here." "On my count." "One, two, three." "CBC, type and cross four units." "Lateral C-spine,not?" " His homeys are there." "They came here?" "Those bastards!" "You stay away from him, okay?" " Take it outside!" " Just stay away!" "Your brother's a ranker." "You almost killed him!" "What more do you want?" "!" "You know?" "Call the cops!" "They're murderers!" "They did it." "You pushed that guy right over the rail!" "You didn't even know that man!" "He was just trying to help, and you pushed him over!" "All he wanted was a chance!" "At the moment, his C-4 nerve, the one between the fourth and fifth vertebrae, is still functioning." "Meaning he can move his diaphragm and shrug his shoulders." "But if the swelling continues, then he becomes a C-3." "He will lose the ability to breathe on his own." "How


a CT." " Drill the burrholes up in the O.R." " Where are you going?" " I'm bagging him." "Not anymore." "Go." " Dr. Benton." " Thank you." "He's a little disappointed I left Surgery." "I'm Miss Corday." "Could you point me towards Casualty?" "Sorry. "Trauma. " I mean Trauma." "Trauma's that way." "You need help?" " I'll call out if I get lost." " You okay?" "Kid was trying to get out of a gang." "You're in the ER." "Get them on the elevator alive, you've done your job." "How do you think he'll do?" "A blown left pupil, probably means a chronic vegetative state." "If he doesn't bleed to death first." "How bad's he look?" "His ST's are sky-high in two, three, and F. His father"I was mostly meat and potatoes." "But now I'm 82." "I'm a man." "I'm breathing." "The odds are 12-to-1 in my favor." "I'm getting it anytime I want." "Not too bad, old age." "I'm glad to hear it." "Glad to hear it." "It feels good to save a man who's performing such a service to society." "Stud service." "Get that in." "He was found outside the Stones concert." "It looked like he fell through a sheet of plate glass." " Easy." " No, no, no." " We're just gonna" " No, no!" " It's okay." " No!" "Don't touch me!" " Get Security." " Security!" " Everything's okay." " Get away from me." "It's all right." "Just relax." "No!" "Stay away from me!" "It's all right." "I'm sick,


to 89." " He's getting dusky." "Two of Versed." "We can't wait any longer." "Once this sedative takes effect, I'll intubate your husband." "When you wake up, you're gonna have a tube helping you to breathe." "Mind if we interrupt?" "Miss Cruz's brother came out of surgery." "The head CT showed no bleeding." "That is really good news." "Thanks." "The boy?" "The boy's gonna be okay?" "Yes, sir." "Thank you." "You saved my brother's life." "That's good." "Can you feel that, honey?" "I'm in." "Is he breathing?" "We're breathing for him now." "Dr. Greene, you need to come now!" "Excuse me." " What happened?" " He went into fib." "Clear!" "He went into asystole." "I've given high-dose epi and atropine." " Charge, 360." " Why didn't you callmodifications to the engine model we have considered do not improve the efficiency significantly.

![Dependence on the channel length of various parameters of the 1D mixed gas. From these results it is clear why when $ZT$ can be very large for a long channel, the new merit $YT$ that governs the efficiency of the engine model (Fig. \[Fig1\]) takes a lower value instead.[]{data-label="Fig4"}](fig4.EPS){width=".95\columnwidth"}

Let us now explain why our engine works at a rather low efficiency in spite of the fact that $ZT$ goes to infinity. In order to derive a theoretical expression for the efficiency we use thermodynamic linear response relations for the heat currents $J_{Q,A}$, $J_{Q,B}$, and for the particle currents $J_{\rho,A}$, $J_{\rho,B}$, in the channels A and B, respectively, namely $$\begin{aligned}
J_{Q,A}&=&-\kappa_A'\Delta T/L_A -T\sigma_A S_A (\Delta \mu/L_A +U_A)
\nonumber\\
J_{\rho,A}&=&-\sigma_A


Fetal endocrinology and development--manipulation and adaptation to long-term nutritional and environmental challenges.
This article reviews the fetal endocrine system in sheep, a species that has a long gestation and primarily produces a singleton fetus. Attention is focused on information that is applicable to humans. The endocrinology of metabolic homeostasis in sheep fetuses is well adapted to respond to a range of metabolic challenges, including placental restriction and maternal undernutrition. A small placenta results in hypoxaemia, hypoglycaemia, reduced abundance of anabolic hormones, and fetal growth restriction. Fetuses with restricted growth are characterized by tissue-specific reductions in hormone receptor mRNA, for example mRNA for the long form of prolactin receptor is reduced in adipose tissue. In contrast, the adipose tissue of fetuses with accelerated growth, stimulated by increasing maternal nutrition in= 3.596, p < 0.001). Advancing year at the faculty was highly statistically significantly associated with greater knowledge about health effects of the pill (ρ = 0.506, p < 0.001). There was no difference regarding attitude score among users and non-users (t = -0.9, p = 0.369). In the multivariate regression model the knowledge score was the only predictor of pill use. The results of our survey indicate that oral contraceptive pill requires further promotion and reproductive health education in a broader context.


return arr.indexOf(val);
    } :

    function(arr, val) {
        for (var i = 0, len = arr.length; i < len; ++i) {
            if (typeof arr[i] != "undefined" && arr[i] === val) {
                return i;
            }
        }
        return -1;
    };

csubSorted = csub.sort(function(a,b){
    return indexOf(originalData, a.value) - indexOf(originalData, b.value);
});

Q:

python replacing item in list

Hi my question relates to a post a long time ago by some user here:
Find and replace string values in Python list
For my specific situation. I have a list like this:
appl =  ['1', 'a', 'a', '2', 'a']

I want to replace only the "a single unknown" instance of "a" with just an empty space(that holds the position of where "a" used to be). I am unsure of how to do it for only one character. Can anyone help? Thanks in advance.
EDIT: i Should mention that I need to use an "index" function to first locate the "a" since it is a changing variable. And then I need code that will replace the character.
EDIT2: A lot of people are assuming the index will be 2,


Background {#Sec1}
==========

Secondary hyperparathyroidism (SHPT) is a common comorbidity in patients with chronic kidney disease (CKD) and, particularly in those on hemodialysis (HD) \[[@CR1]\]. Due to an unpredictable bone resistance to parathyroid hormone (PTH) action, maintaining a mild biological SHPT is recommended in most HD patients to favor a normal bone turnover rate. According to the most recent international Kidney Disease Improving Global Outcomes guidelines, experts recommend target serum PTH levels of 2 to 9 times the upper normal limit of the assay in HD patients \[[@CR2]\]. Identification of bone turnover rate from serum PTH levels, however, is not straightforward. Bone histology studies have shown that SHPT can be excluded by lower serum PTH levels and adynamic bone disease (ABD) by higher serum PTH levels \[[@CR3]\]. Between these twofor the SPD group and 24 months for the MPD group (*p* \< 0.001).

The comorbid conditions and therapeutic changes associated with a decrease in PTH in the SPD and the MPD groups are reported in Tables [3](#Tab3){ref-type="table"} and [4](#Tab4){ref-type="table"}, respectively. Among patients in the SPD group, the main acute comorbid conditions were peripheral vascular and cardiac complications, sepsis, fractures, and cancers with an increase in serum CRP level (from 14.3 ± 18 to 132 ± 90 mg/L) and a decrease in serum albumin (from 33 ± 4.5 to 28.6 ± 4 g/L). In the MPD group, the main therapeutic change associated with a decrease in PTH was an increase in DCC, either independently or in association with cinacalcet therapy, and less frequently associated with the prescription of oral calcium or alfacalcidol.Table 3Comorbid conditions associated with spontaneous PTH decrease (SPD)SPD\
*N* = 68 (35 %)Peripheral vascular disease-arterial


low PTH levels were associated with a higher rate of mortality \[[@CR11]\]. The same findings were confirmed for patients with CKD not on dialysis by Kovesdy et al. \[[@CR7]\] and Nakai et al. in Japan \[[@CR28]\]. The mechanism of PTH toxicity is poorly understood. However, an elevated calcium x phosphorus (Ca x P) product associated with tertiary HPT and a high serum PTH level, associated with high serum FGF-23level, have been associated with a risk for progression of cardiovascular calcification \[[@CR5], [@CR29]\].

Low PTH-related mortality {#Sec8}
-------------------------

In patients with CKD and in those on HD in particular, both low and high serum PTH levels have been associated with a higher rate of mortality \[[@CR30]\]. Twenty years ago, Fournier et al. reported that a persistently low PTH state could result fromimpact of a decreased PTH level {#Sec10}
------------------------------------------

In a French observational study, using the KDIGO biological target of PTH level, Merle et al. reported that a decrease in serum PTH level after one year, including both changes from normal to low levels and from high-to-low levels, was associated with a higher rate of cardiovascular-related mortality \[[@CR16]\]. Among factors associated with a higher risk of mortality, Merle et al. identified a high serum CRP level and a high DCC (1.75 mmol/L). Of importance is their finding that mortality risk increased when high DCC and a low albumin level were associated with a PTH decrease; high DDC was not associated with an increased rate of mortality among patients in whom PTH level remained in the low range. However, Merle et al.'s study


was based only on biannual PTH sampling, and information on acute comorbid conditions or changes in therapeutic intervention was not available between sampling periods. Moreover, high DCC was prescribed in their study based on usual care rather than being individualized based on PTH values. We consider that using the KDIGO target level (i.e., low-normal-high level classification) to study PTH variations may be questionable as a small variation in PTH level could be associated with a change in target zone classification. In the COSMOS study of 4500 European HD patients evaluated at 6-month intervals, Fernandez-Martin et al. reported that a serum PTH decrease was not associated with an increased rate of mortality when baseline PTH levels were within the KDIGO range of normal (168 -- 674 pg/mL), with the riskof mortality significantly increasing among patient with a baseline PTH level \<168 pg/mL \[[@CR15]\]. Again, no data on acute comorbid conditions or change in therapeutic intervention was provided. We hypothesize that a decrease in PTH among patients in the low level KDIGO range would reflect an acute comorbid condition, rather than a medical decision on treatment, which would explain the finding of a higher rate of mortality. In their large US-based cohort study of HD patients, Streja et al. reported that an increased in serum PTH level from \<150 pg/mL to 150--300 pg/mL was associated with a lower risk of mortality \[[@CR60]\]. Once again, this was an observational study with no information on the underlying cause of variation in PTH level provided.

Limitations {#Sec11}
-----------

The fact that we conducted a monocentric study with


(2), and the driving shaft S is moved fast in the direction along which the shaft is separated from the fixed member B. At this time, the acceleration of the driving shaft S is so high that the inertia force of the moving member M is larger than the friction force exerted between the moving member M and the driving shaft S, and hence the driving shaft S is moved while the moving member M is not substantially moved.
When the voltage applied to the piezoelectric element A is thereafter lowered slow from the maximum voltage to the reference voltage as indicated by (3) in FIG. 1(B), also the driving shaft S is moved slow in accordance with the lowering as shown in (3) of FIG. 1(A). At thisended, charges remain to exist in the piezoelectric element A. In the case where the driving operation is thereafter conducted in the opposite direction, therefore, the polarity of the piezoelectric element A is suddenly inverted. Consequently, a large potential difference is abruptly produced in the piezoelectric element A, so that a sound is generated also in this case. The piezoelectric element A may be sometimes destroyed depending on the potential difference.
By contrast, even in the case where the piezoelectric element A is charged slow and then discharged fast, when the driving operation is conducted with the opposite polarity after the driving operation is stopped under a state where the piezoelectric element A is charged, a sound is generated because of the following reason. Even if the driving operation


Splay Silver Plated Wine Decanter Funnel With Stand

The Splay Silver Plated Wine Decanter Funnel Silver plated and comes with a removable fine screen S/S filter with attached stem. Wine flows through three holes just above the closed bottom of the The Splay Silver Plated Wine Decanter Funnel. This causes the wine to splay, or spread outward, down the inside walls of the decanter. This oxygenates the wine more, enhancing the fragrance and aroma of the wine.

Product Description

The Splay Silver Plated Wine Decanter Funnel Silver plated and comes with a removable fine screen S/S filter with attached stem. Wine flows through three holes just above the closed bottom of the The Splay Silver Plated Wine Decanter Funnel. This causes the wine to splay, or spread outward, down the insideInstitute of Oceanography, Universiti Malaysia Terengganu, Malaysia.

Threats

Threats to sea turtles occur at practically all stages in their life-cycle. Their nesting beaches are threatened by beachfront developments, poorly managed tourism activities and sand mining. Their eggs are still commercially harvested in some parts of Malaysia. The hatchlings lead a pelagic life and are threatened by pollution like tar balls, plastics and styrofoam. The juveniles of many species of turtles depend on coastal habitats as feeding grounds. Destruction and loss of these habitats to human activities can seriously affect their survival. The adults are often caught in fishing gears, either incidentally or for their shell and meat. All these threats are compounded by their slow growth and long maturation time in the wild.

Nesting beaches

Turtles typically seek dark and undisturbed beaches


In case of calorimetric measurements, the mixtures prepared in this way were then melted at T = 470 K, during the first DSC scan, and vitrified by fast cooling (20 K/min) during the second DSC scan. Sample preparation for the BDS measurements involved melting the binary physical mixtures at T = 470 K, followed by vitrification on a previously chilled copper plate. All measurements were performed immediately after preparation of the amorphous systems, to avoid recrystallization.

2.3. Differential Scanning Calorimetry {#sec2dot3-pharmaceutics-12-00460}
--------------------------------------

The thermodynamic properties of SIL, KVA, PVAc and their binary systems were examined using a Mettler--Toledo DSC 1 STAR^e^ System (Columbus, OH, USA). The measuring device was equipped with a HSS8 ceramic sensor with 120 thermocouples. The instrument was calibrated for temperature and enthalpy using indium and zinc standards.range of 600--4000 cm^−1^ with a resolution of 1 cm^−1^ and a minimum of 40 scans were collected and averaged. The spectra were then normalized and background corrected \[[@B51-pharmaceutics-12-00460]\]. An infrared analysis was carried out on crystalline as well as amorphous SIL and SIL-based ASD samples, which were first melted at 468 K and then quenched.

3. Results and Discussion {#sec3-pharmaceutics-12-00460}
=========================

3.1. Thermal Properties of SIL-Based Mixtures {#sec3dot1-pharmaceutics-12-00460}
---------------------------------------------

Thermal properties of neat components (amorphous SIL and KVA and PVAc polymers) and their binary amorphous mixtures, in the form of amorphous solid dispersion (ASD) systems (SIL + 25 wt.% KVA, SIL + 50 wt.% KVA, SIL + 75 wt.% KVA, SIL + 25 wt.% PVAc, SIL + 50 wt.% PVAc and SIL + 75 wt.% PVAc) were examined using DSC. During these


obtained from calorimetric as well as dielectric measurements was confirmed for the example of amorphous gambogic acid, based on the heating rate dependence of Tg calculated using the Elastically Collective Nonlinear Langevin Equation (ECNLE) theory \[[@B69-pharmaceutics-12-00460]\].

Upon heating above the T~g~, at a certain temperature, one can observe a significant decrease in the intensity of the structural relaxation peak (visible on dielectric loss spectra---marked as the red dashed line in [Figure 3](#pharmaceutics-12-00460-f003){ref-type="fig"}), which corresponds to the decrease in the dielectric strength. Taking into account that the dielectric strength is proportional to the number of units (N), with a dipole moment (μ) involved in the structural relaxation (Δε ∼ Nμ^2^), and the fact that the number of reorienting dipoles, contributing to the α-relaxation, decreases as the crystallization process progresses \[[@B70-pharmaceutics-12-00460],[@B71-pharmaceutics-12-00460]\],[Figure 6](#pharmaceutics-12-00460-f006){ref-type="fig"}A). Considering the non-isothermal measurements performed in this work, the enhancement of the physical stability exerted by this specific amount of the antiplasticizing polymer is, therefore, only apparent. The explanation of this result is related to the fact that although the temperature range in which the sample is stable in the supercooled liquid state (above T~g~) was shifted towards higher values, its actual range is narrower. Nevertheless, a further increase in the polymer content resulted in a higher thermal stability factor than in the case of amorphous SIL. Additionally, for the PVAc-based systems, one can observe that each subsequent concentration of the plasticizer used has a higher thermal stability factor than the neat drug (see [Figure 6](#pharmaceutics-12-00460-f006){ref-type="fig"}B). This result, although unexpected, because 25 wt.% addition of PVAc


case of the recrystallization of SIL + 25 wt.% PVAc at 353 K, both SIL + 25 wt.% KVA and PVAc samples did not recrystallize fully. The noteworthy observation is that both samples (SIL + 25 wt.% KVA and PVAc) start to recrystallize after nearly the same time as the neat SIL (see [Figure 7](#pharmaceutics-12-00460-f007){ref-type="fig"}C). Moreover, the crystallization process of both SIL + 25 wt.% PVAc, as well as the neat SIL at isochronal conditions, is very similar (both the induction times as well as the time when the recrystallization ceases---see wine hexagons and triangles, respectively, in [Figure 7](#pharmaceutics-12-00460-f007){ref-type="fig"}C). This result could be explained by the fact that either: i) the molecular dynamics is the crucial factor affecting physical stability of amorphous API, which would be in agreementtendency towards recrystallization at this temperature (see [Figure 9](#pharmaceutics-12-00460-f009){ref-type="fig"}B).

The 75 wt.% PVAc sample, in contrast to that comprising 25 wt.% PVAc, showed a deceleration of the recrystallization process of amorphous SIL. This phenomenon confirms that at a certain concentration, PVAc will cease to accelerate the SIL recrystallization process and start to inhibit it. Furthermore, it should be mentioned that this sample did not recrystallize completely. Moreover, because the sample containing 25 wt.% of the API still recrystallizes while stored at 353 K, one can conclude that the solubility of the SIL in the PVAc matrix at this temperature is lower than 25 wt.% (the exact concentration was not determined).

Finally, during the measurements at isochronal conditions both samples (SIL + 75 wt.% KVA and SIL + 75 wt.% PVAc)


the physical stability of the amorphous SIL. The presented work shows that despite the significant changes in the sample's molecular mobility, exerted by the antiplasticizing (KVA) and plasticizing (PVAc) polymers, both of these excipients are able to effectively stabilize amorphous form of the investigated API. Considering the drug-polymer concentrations, far above the solubility limits, the measurements at either: isothermal (353 K) or isochronal (τ~α~ = 1.5ms) conditions, indicated that KVA-based samples were characterized by a better physical stability in comparison to the PVAc-based systems. Furthermore, the results indicate that the 25 wt.% addition of PVAc accelerates the recrystallization of the amorphous SIL when stored at the same temperature (353 K). Based on the isochronal measurements (at τ~α~ = 1.5ms), the 25 wt.% addition of PVAc (which resulted inalso do it with ROW_NUMBER():
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Thanks. :)

A:

jQuery
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 under stressful conditions, which the researchers imposed by adding different concentrations of an antibiotic to the culture. As Opitz explains, stress in the form of the antibiotic activates a specific type of SOS function in the bacteria, which triggers countermeasures and promotes toxin production (while the antibiotic also reduces overall growth rates).

In the absence of the stress induced by the addition of the antibiotic, the sensitive strain, which was present in 100-fold excess over the toxin producer at the outset, usually won out, although stable coexistence of both strains was also observed under these conditions. In cultures containing low levels of the antibiotic, on the other hand, the division of labor within the producer population gave it a decisive advantage, and in the vast majority of cases, it


development, Stephen knew immediately he could never allow his child to be raised as an Abnaki. The heathen savages refused to permit the introduction of Christianity into the community, and Stephen was well aware of what that meant for his child: suffering in the fires of hell for all eternity. Although he had never met his baby, although he had only known for twenty-four hours that he even had a baby, Stephen realized he must do something to give his little daughter the opportunity to experience eternal salvation.

So he had begged the Native girl for a chance to meet the infant, to see his child if only once, and she reluctantly agreed. Stephen thought how strange it was to have fathered a baby with a savage girl whosehe could not move. Stephen knew that unless someone helped him, and soon, he was going to die. He was surprised to discover the prospect didn’t frighten him.

Moving his head, which seemed to be the only part of his body he could convince to work properly, Stephen scanned as much of the area as he could see. Bodies littered the forest, some of them Abnaki tribal warriors and some of them missionaries; men Stephen had lived and worked with for the past three years. A few of them were moaning softly, but most lay unspeaking and unmoving. Stephen suspected the majority of them were dead. Blood was everywhere, congealing on every surface, more blood than Stephen would ever have imagined possible.

His most pressing thought—his only clear thought, really—was


while Johnson is Majority Leader in the Senate, segregation hits the national consciousness. His long-standing support for the poor and downtrodden suddenly coincides with a recognition that many of those are not only black; but are poor and downtrodden because of being black. At that moment the driven, ambitious, and yes, racist, Senator from Texas steps up to the challenge; confronts one of his own demons; and conquers it. He remakes himself  as a Civil Rights Champion.
It seems appropriate to note here that, as President, Johnson was uniquely qualified in a manner that few of his predecessors, and none of his successors to date, have been: as a former Majority Leader of the Senate, Johnson understood the legislative process far better than most presidents. Johnson had
Active-Shooter Drills Are Tragically Misguided - Pharmakon
https://www.theatlantic.com/magazine/archive/2019/03/active-shooter-drills-erika-christakis/580426/
======
randyrand
The most ironic effect of school shooter training is that it encourages more
school shootings.

I was surprised that "you look like you'd shoot up a school" is becoming a
relatively common insult in middle school kids.

The more society thinks about school shootings, the more mentally troubled
people will think about school shootings.

Shooting up schools is a fad. Just like many other types of murders have gone
through fads (mail bomber). Copy cat murderers are our biggest problem, and
becoming hysterical when school shootings happen is why copy cats are so
prolific.

~~~
mariuolo
> The most ironic effect of school shooter training is that it encourages more
> school shootings.

It has a normalising effect, but then if schools didn't do it, perhaps they
could be sued by parents when something happened?

~~~
tazard
Perhaps now they


the ground and stay flat while moving toward concealment and cover

------
vmh1928
better to have a basket of spears and some bows & arrows in every classroom
and have active-shooter bayonet and archery practice. Nothing like practicing
cowering in fear. Fight back with _something_.

of how Washington, DC tastes when curated by local bees.

We hold community harvests for our beekeepers (especially first harvest experiences) once or twice a year to give them access to tools and to training on how to extract. Over the past few years, however, we have discovered the power of showing non-beeks how to bring home the gold, and to connect the dots between city living and the green world.

How to Make Honey Flow for Non-Beeks

Non-beekeeper honey harvests have taken a couple of forms, roughly: 1) educational settings; and 2) community-building fundraisers, but there is no reason this kind of tool could not be used for other goals. Here’s a short discussion of how and why we do it in educational settings, to be followed next month by


Ambassador” Program of the Washington Youth Garden. In each of these settings, we make sure that participants take some part of the harvest home in order to bring the lesson there (if you hook the kids, you probably get the family as a bonus). At two sites, a significant part of the harvest is sold via the PTA or school garden program to finance the programs which invite in the bees. By the way, this reaches additional hundreds of community members who become accustomed to hearing about bees, children, and their neighborhood in the same sentence without freaking out.

If you reckon that we are letting go of a whole lot of honey, that’s pretty much correct, except in the cases where our early harvests promoted the establishment ofQ:

Why are Embeddings in PyTorch implemented as Sparse Layers?

Embedding Layers in PyTorch are listed under "Sparse Layers" with the limitation:

Keep in mind that only a limited number of optimizers support sparse gradients: currently it’s optim.SGD (cuda and cpu), and optim.Adagrad (cpu)

What is the reason for this? For example in Keras I can train an architecture with an Embedding Layer using any optimizer.

A:

Upon closer inspection sparse gradients on Embeddings are optional and can be turned on or off with the sparse parameter:

class torch.nn.Embedding(num_embeddings, embedding_dim, padding_idx=None, max_norm=None, norm_type=2, scale_grad_by_freq=False, sparse=False)

Where:

sparse (boolean, optional) – if True, gradient w.r.t. weight matrix
  will be a sparse tensor. See Notes for more details regarding sparse
  gradients.

And the "Notes" mentioned are what I quoted in the question about a limited number of optimizers


child care for > or =10 hours/week. Intervention families received a supply of hand sanitizer and biweekly hand-hygiene educational materials for 5 months; control families received only materials promoting good nutrition. Primary caregivers were phoned biweekly and reported respiratory and GI illnesses in family members. Respiratory and GI-illness-transmission rates (measured as secondary illnesses per susceptible person-month) were compared between groups, adjusting for demographic variables, hand-hygiene practices, and previous experience using hand sanitizers. Baseline demographics were similar in the 2 groups. A total of 1802 respiratory illnesses occurred during the study; 443 (25%) were secondary illnesses. A total of 252 GI illnesses occurred during the study; 28 (11%) were secondary illnesses. The secondary GI-illness rate was significantly lower in intervention families compared with control families (incidence rate ratio [IRR]:on each count.  On appeal the defendant urges that reversal of his conviction is required because (1) the evidence was insufficient in a number of particulars; (2) the trial court erred in refusing to grant a requested continuance; (3) the trial court erred in refusing to require the government to give notice of certain evidence to be used at trial; and (4) a number of the trial court's evidentiary rulings constitute reversible error.  We have thoroughly reviewed the record and find no prejudicial error.

2
I. Background.

3
The charges against the defendant resulted from his activities as a vendor of food stamps in the State of Missouri.  The defendant and his partner, Richard Watkins, owned a corporation called Moneytown, Incorporated.  Through a number of locations primarily in


was inadequate for the defendant to fully examine Moneytown's financial records.  Furthermore, even if the defendant had been able to explain fully where the funds had actually gone, the FNS 250 forms which formed the basis for the indictment would be no less false with regard to the deposits listed.  Our examination of the record indicates that the government's references to the amount of money missing, or the amount misstated on Moneytown's FNS 250 forms, were relevant to negate the defendant's contention that he merely made a good faith mistake as to the amount of money deposited and was totally unaware that deposits were not being made.

33
The rule is well established that the decision to grant a continuance rests in the sound discretion of the trialwere recorded after 1000 B.C.

Ayurveda, Unconditionally True:

The definition of ‘truth’ as in ‘vedas’ emphasis on being true at all varying condition like time, place or anything. It can be seen that the principles of Ayurveda are retained intact and the medicinal formulations in the reference texts are narrated as examples of this treatment theory for individual diseases.

Ayurveda and Lord Dhanwanthari:

it is a part of the indian philosophy to create multi level statements or icons to communicate with different levels of audience at a time, The real meaning is kept for learned ones, while the objective of installing a system or ritual is achieved successfully. One example of such an icon is Lord Dhanwanthari is known as the God of Medicine and the whole healing system is maintained thus


for the *Teichmüller metric*. The *Teichmüller geodesic flow* $\Phi^t$ on ${{\mathcal{Q}}}^1(S)$ commutes with the action of the *mapping class group* ${{\mathcal{M}}}(S)$ of all isotopy classes of orientation preserving self-homeomorphisms of $S$. Thus this flow descends to a flow on the quotient ${{\mathcal{Q}}}(S)=
{{\mathcal{Q}}}^1(S)/{{\mathcal{M}}}(S)$, again denoted by $\Phi^t$.

For a quadratic differential $q\in {{\mathcal{Q}}}^1(S)$ define the *unstable manifold* $W^u(q)\subset{{\mathcal{Q}}}^1(S)$ to be the set of all quadratic differentials whose vertical measured geodesic lamination is a multiple of the vertical measured geodesic lamination for $q$. Then $W^u(q)$ is a submanifold of ${{\mathcal{Q}}}^1(S)$ which projects homeomorphically onto ${{\mathcal{T}}}(S)$ [@HM79]. Similarly, define the *strong stable manifold* $W^{ss}(q)$ to be the set of all quadratic differentials whose horizontal measured geodesic lamination coincides with the horizontal measured geodesic lamination of $q$. The sets $W^u(q)$ (or $W^{ss}(q)$) $(q\inmaps $\sigma$ into $\tau$ in such a way that the restriction of the differential of $F$ to the tangent space of $\sigma$ vanishes nowhere; note that this makes sense since a train track has a tangent line everywhere. We call the restriction of $F$ to $\sigma$ a *carrying map* for $\sigma$. Write $\sigma\prec
\tau$ if the train track or the geodesic lamination $\sigma$ is carried by the train track $\tau$.

A *transverse measure* on a maximal generic train track $\tau$ is a nonnegative weight function $\mu$ on the branches of $\tau$ satisfying the *switch condition*: For every switch $s$ of $\tau$, the sum of the weights over all incoming branches at $s$ is required to coincide with the sum of the weights over all outgoing branches at $s$. The train


track $\tau$ to another complete train track. First, we can *shift* $\tau$ along a mixed branch to a train track $\tau^\prime$ as shown in Figure A below. If $\tau$ is complete then the same is true for $\tau^\prime$. Moreover, a train track or a lamination is carried by $\tau$ if and only if it is carried by $\tau^\prime$ (see [@PH92] p.119). In particular, the shift $\tau^\prime$ of $\tau$ is carried by $\tau$. Note that there is a natural bijection of the set of branches of $\tau$ onto the set of branches of $\tau^\prime$.

![image](WeicheII.eps)

Second, if $e$ is a large branch of $\tau$ then we can perform a right or left *split* of $\tau$ at $e$ as shown in Figure B. Note that a right split at $e$ is uniquelyis a distance $d$ on $K$ defining the subspace topology and there is a constant $a>0$ such that every point $z\in K$ has an open neighborhood $U$ in $Y$ which is homeomorphic to a product $U=U_1\times U_2$ and such that the following holds.

1.  For all $y\in U_2$, all $x_1,x_2\in U_1$ such that $(x_i,y)\in K$ $(i=1,2)$ and all $t>0$ we have $d(\Theta^t(x_1,y),\Theta^t(x_2,y))\leq e^{-at}/a$.

2.  For all $x\in U_1$, $y_1,y_2\in U_2$ with $(x,y_i)\in K$ $(i=1,2)$ there is a number $s\in [-1/a,1/a]$ such that $d(\Theta^{-t}(x,y_1),\Theta^{-t+s}(x,y_2))\leq e^{-at}/a$ for all $t>0$.

We show.

\[hyperbolic\] Every $\Phi^t$-invariant compact subset $K$ of ${{\mathcal{Q}}}(S)$ is a topological hyperbolic set for $\Phi^t$.

Let as before $\chi_0>0$ be such that for every complete hyperbolic metric on $S$ of finite volume there is a pants decomposition consisting of pants curves of


train tracks on $S$ is topologically mixing.

By Lemma \[mixing\], it is enough to find some numbered combinatorial types $i,j\in \{1,\dots,k\}$ such that our transition matrix $A=(a_{ij})$ satisfies $a_{ij}=1=a_{ij}^{(2)}$. However, such numbered combinatorial types of train tracks are shown in Figure C below. Namely, the train tracks $1RR$ and $2R$ are numbered shift equivalent, and the same is true for the train tracks $1L$ and $2LL$. To complete the proof of the corollary, simply observe that any large branch in a complete train track $\tau$ incident on a switch $v$ with the property that at least one of the branches of $\tau$ which is incident on $v$ and small at $v$ is *not* a small branch defines a configuration as in Figure C. In particular, every large branch ofmaximal weight that is disposed by $\lambda^+\in{{\mathcal{V}}}(\tau_0)$ on a large branch of $\tau_0$ is one and hence the total weight of the transverse measure on $\tau_0$ defined by $\lambda^+$ is uniformly bounded. Thus by Corollary 2.3 of [@H06a], the intersection number between $\lambda^+$ and any vertex cycle of $\tau_0$ is uniformly bounded.

By the results of [@MM99], the number of vertex cycles for a complete train track $\tau$ is uniformly bounded. Since the space ${{\mathcal{V}}}(\tau)$ of transverse measures on $\tau$ is spanned by the vertex cycles, there is a decomposition $\lambda^+=\sum_ia_ic_i$ where $a_i\geq 0$ and $c_i$ are the vertex cycles of $\tau_0$. Now the number of vertex cycles is uniformly bounded and hence we have $a_i>\epsilon$ for a universal number $\epsilon >0$ and at least one $i$. Then the


measure on the space of projective measured geodesic laminations whose measure class is invariant under the action of ${{\mathcal{M}}}(S)$ and where $f$ is a positive measurable function. Since the action of ${{\mathcal{M}}}(S)$ on ${{\mathcal{P}}{\mathcal{M}}{\mathcal{L}}}$ is minimal, the measures $\mu^+,\mu^-$ are of full support. Now the horizontal measured geodesic lamination of a typical point for the measure $\mu$ on ${{\mathcal{Q}}}(S)$ is uniquely ergodic and fills up $S$ and hence if $v,w$ are typical points for $\mu$ on the same strong stable manifold in ${{\mathcal{Q}}}(S)$ then $\lim_{t\to\infty}d(\Phi^t
v,\Phi^t w)=0$ for a suitable choice of a distance function $d$ on ${{\mathcal{Q}}}(S)$ [@M80]. From continuity of the function $\phi$ and absolute continuity of $\mu$ with respect to the strong stable and the unstable manifolds we deduce that $\psi(v)=\psi(w)$. Similarly we argue for theprojective measured geodesic laminations $x,y$ together fill up $S$. Such neighborhoods are well known to exist. Then every pair $(x,y)\in V^+\times V^-$ determines a unique Teichmüller geodesic. Define a *cross ratio* function $\sigma:V^+\times V^-\to \mathbb{R}$ as follows. Choose a quadratic differential $q\in {{\mathcal{Q}}}^1(S)$ whose horizontal measured geodesic lamination $\lambda^+$ is in the class $u^+$ and whose vertical measured geodesic lamination $\lambda^-$ is in the class $u^-$. For $y\in V^-$, the pair $(u^+,y)$ defines a Teichmüller geodesic whose corresponding one-parameter family of quadratic differentials intersects $W^{ss}(q)$ in a unique point $\alpha_1(x,y)$. Similarly, the family of quadratic differentials defined by the pair $(x,y)$ intersects $W^{su}(\alpha_1(x,y))$ in a unique point $\alpha_2(x,y)$, the family of quadratic differentials defined by the pair $(x,u^-)$ intersects $W^{ss}(\alpha_2(x,y))$ in a unique point $\alpha_3(x,y)$, and finally the


of $\tau(j)$ to be a complete train track $\sigma$ which can be obtained from $\tau(j)$ by splitting $\tau(j)$ at each large branch precisely once. Since splits at different large branches of $\tau(j)$ commute, the numbering of the branches of $\tau(j)$ induces a numbering of the branches of $\sigma$. Thus the train tracks $\sigma^1,\dots,\sigma^\ell$ obtained from $\tau(j)$ by a full split are numbered. We obtain a decomposition $W^+(j)=\cup_{i=1}^\ell W^i$ into Borel sets $W^i$ where $W^i\subset W^+(j)$ consists of the set of all projective measured geodesic laminations which are carried by $\sigma^i$ ($i=1,\dots,\ell$). For $i\not=j$ the intersection $W^i\cap W^j$ is contained in a hyperplane of ${{\mathcal{P}}{\mathcal{M}}{\mathcal{L}}}$ (with respect to the natural piecewise linear structure which defines the Lebesgue measure class) and hence it has vanishing Lebesgue measure. If $k(i)\in {{\mathcal{E}}}$topologically mixing (or even transitive), we can apply the same consideration as above. Namely, since set of uniquely ergodic minimal and maximal measured geodesic laminations has full Lebesgue measure, there is a finite sequence $(y_i)_{0\leq i\leq k}\subset {{\mathcal{E}}}$ with $p_{y_iy_{i+1}}>0$ for all $i$ and there is a number $\ell >0$ such that for every full splitting and shifting sequence $\{\tau_i\}_{0\leq i\leq k}$ which realizes $(y_i)$ in the above sense, the sequences $\{\tau_i\}_{0\leq i\leq \ell}$ and $\{\tau_i\}_{\ell\leq i\leq k}$ are tight in the sense described before Lemma 4.6. As in the proof of Lemma 5.2, from this observation the proposition follows (compare also the discussion in [@K85]).

The critical exponent of ${{\mathcal{M}}}(S)$
=============================================

In this section we derive the first part of Theorem C from the introduction. Namely, we show that the


is a number $a>0$ such that for all $q,z\in U$ we have $\lambda_q(D(z,\chi))\leq a$.

3.  The family ${{\mathcal{V}}}$ of all pairs $(F\pi(q),gD(q_1,\chi))\mid q\in W^{su}(q_1,\Phi^tq\in gU$ for some $t>0\}$ is a Vitali relation for $\lambda_{q_1}$.

By the proof of Proposition 3.3 of [@H07], there is an open relative compact subset $W$ of $W^{su}(q_1)$ with the property that $V=F(\pi(W)\cap {{\mathcal{F}}{\mathcal{M}}{\mathcal{L}}})$ is an open neighborhood of $F\pi(q_1)$ in $\partial{{\mathcal{C}}}(S)$. Let $\alpha>0$ be the diameter of the projection of $W$ to ${{\mathcal{T}}}(S)$. By 3) above there is a countable set $G_1=\{g_i\mid i>0\}\subset {{\mathcal{M}}}(S)$ such that the sets $g_iD(q_1,\chi)=D(g_iq_1,\chi)$ $(g_i\in G_1)$ are pairwise disjoint, are contained in $V$ and cover $\lambda_{q_1}$-almost all of $V$. Moreover, for each $i$ there is some $p_i\in W\cap A$ and some $t_i>0$ such that $\Phi^{t_i}p_i\in g_iU$. By 2) abovethe shortest closed geodesic on the hyperbolic surface $x$. For a periodic geodesic $\gamma:[0,1]\to {\rm Mod}(S)$ write $s(\gamma)=\max\{s(\gamma(t))\mid t\in [0,1]\}$. We have.

\[lengthbound\] There is a constant $\kappa>0$ such that the length of every closed geodesic in ${\rm Mod}(S)$ is at least $(-\log s(\gamma)-\kappa)/(3g-3+m)$.

Let $\chi>0$ be sufficiently small that for every complete hyperbolic metric $h$ on $S$ of finite volume and every closed geodesic $c$ for the metric $h$ of length at most $\chi$, the length of every closed $h$-geodesic which intersects $c$ nontrivially is bigger than $2\chi$. Via an appropriate choice of the constant $\kappa >0$ in the statement of the lemma, it is enough to show the lemma for closed geodesics $\gamma$ in moduli space with $s(\gamma)\leq \chi$.

Thus let $\gamma:[0,1]\to {\rm Mod}(S)$ be such a closed geodesic


and let $\gamma$ be a closed geodesic in moduli space of length $\ell(\gamma)$. Let $\chi<1$ be sufficiently small that no two simple closed geodesics with respect to a complete hyperbolic metric of finite volume on $S$ of length at most $\chi$ can intersect. Let $K\subset {\rm Mod}(S)$ be the compact subset of moduli space of all hyperbolic metrics whose systole is at least $\chi$.

Let $x\in {{\mathcal{T}}}(S)$ be a point which projects to a point in $K$ and let $g\in C(\gamma)$ be such that $d(x,gx)=\min\{d(x,hx)\mid h\in C(\gamma)\}$. Assume that $\gamma$ is parametrized in such a way that $s(\gamma)=s(\gamma(0))$. By the triangle inequality and the choice of $g$, there is a constant $a>0$ not depending on $\gamma$ and an element $g\in C(\gamma)$ such that with $R=-\log s(\gamma)$ we have $d(x,gx)\leqand digital rights for

1. Middle East

2. Africa

3. Europe

4. USA

5. Australia and New Zealand.

A jubilant Uday Shankar, Chairman of Star India, wrote to Star employees, “Above all, what makes us successful and win these closely fought battles is who we are. It is in the DNA of this great company to take very few but very big risks and then go about executing them relentlessly in a very disciplined manner. We truly believe in Nayi Soch (new way of thinking) and we truly believe in Bhula De Dar, Kuch Alag Kar (forget fear, do something different) – that’s who we are and that’s what won the day for us today”.

Uday’s message effectively nullifies whoever has been saying that Star’s mind-boggling bid could bring on to it the Winner’s Curse


a family now.

"The great thing about Resident Evil is it's very organic. Every movie we've made, we've made with full-on heart, full-on soul. We have so much fun doing it. It's not like it's a business in the sense of 'Ch-ch next, ch-ch next,' " she says, making what I think is a cash-register sound. "We wait for the reaction. People love it. They want another one. We make another one."

Reminded that the previous Resident Evil: Afterlife knocked off Porky's to become the highest-grossing Canadian-produced movie in history, she yells, "High five!" and offers up her palm.

Well, hey, who are we to leave her hanging?

CONFOUNDING BOX-OFFICE DUDS: Remember when all a movie needed was rave reviews and great word of mouth? No more. Case in point: Warrior, oneat the box office in subsequent weeks. Some might argue that was inevitable since, while it was sold to the Fast and Furious crowd, it owes much more to European cinema. Others will point to its extreme bursts of brutality as what turned off female and older audiences.

So what have proven to be critic-and-crowd-pleasers alike?

All-ages fare, certainly. The success of The Lion King in 3D ($80 million) and Dolphin Tale ($37 million after 10 days) underscore what Hollywood already knows: Never underestimate the appeal of films for the whole family.

But two films for adults have performed well too: The virus thriller Contagion ($64 million), and the Brad Pitt/Jonah Hill-led Moneyball ($38 million); the latter should play well through October.

As for movies that should have flopped and did, two


Patient held clinical information for people with psychotic illnesses.
It is important to seek cost-effective methods of improving the care and outcome of those with serious mental illnesses. Patient-held records, where the person with the illness holds all or some personal information relating to the course and care of their illness, are now the norm in some clinical settings. Their value for those with serious mental illnesses is unknown. To evaluate the effects of personalised and accessible patient-held clinical information for people with a diagnosis of psychotic illness. Electronic searches of AMED (1980-1998), Biological Abstracts (1985-1998), British Nursing Index (1994-1998), CAB (1973-1999), CINAHL (1982-1999), The Cochrane Controlled Trials Register (Issue 1, 1999), EMBASE (1980-1999), HEALTHSTAR (1990-1999), HMIC (King's Fund Database 1979-1998 & HELMIS 1984-1998), MEDLINE (1966-1999), PsycLIT (1887-1999), RoyalSync Panes

You can do this by switching to the appropriate window, typing your Tmux prefix (commonly Ctrl-B or Ctrl-A) and then a colon to bring up a Tmux command line, and typing:

:setw synchronize-panes

You can optionally add on or off to specify which state you want; otherwise the option is simply toggled. This option is specific to one window, so it won’t change the way your other sessions or windows operate. When you’re done, toggle it off again by repeating the command. tip source

Resizing Panes

You can also resize panes if you don’t like the layout defaults. I personally rarely need to do this, though it’s handy to know how. Here is the basic syntax to resize panes:

Copy mode:

Pressing PREFIX [ places us in Copy mode. We can then use


our movement keys to move our cursor around the screen. By default, the arrow keys work. we set our configuration file to use Vim keys for moving between windows and resizing panes so we wouldn’t have to take our hands off the home row. tmux has a vi mode for working with the buffer as well. To enable it, add this line to .tmux.conf:

setw -g mode-keys vi

With this option set, we can use h, j, k, and l to move around our buffer.

To get out of Copy mode, we just press the ENTER key. Moving around one character at a time isn’t very efficient. Since we enabled vi mode, we can also use some other visible shortcuts to move around the buffer.

For example, we can use "w" toa mortar, to lay bigger bits of baked clay bricks or rubble together. The Colosseum was built using brick and concrete around 110 A.D. and must have been a beautiful spectacle in brilliant white travertine, and festooned with many marble sculptures and reliefs.

Whilst it did fall into disuse after the fall of the Roman Empire, its current dilapidated state is mostly due to its deliberate dismantling over the following thousand years by builders, who raided its marble statues and outer cladding blocks in order to build other Roman buildings, including much of what is now Vatican City.

The Pantheon dome from inside.

The Pantheon is the largest unreinforced concrete dome in the world, built in 120 A.D. with a diameter of 43 metres. It was built using pumice as the


linked devices communicate at the highest common speed, regardless of whether the highest speed is needed. Transmissions at higher speeds consume greater power than lower speed transmissions. Moreover, devices may be consuming additional power to transmit at the highest common link speed when such high speeds are not needed. For instance, lower speed transmissions may be sufficient when checking electronic mail or “surfing” the Internet. Power conservation may be especially important for battery powered computing devices, such as laptops, hand held computers, etc., and computers deployed in an energy conservation sensitive environment.
For these reasons, there is a need in the art to provide improved techniques for managing the transmission speed between network devices.not have plans to move the festival in the foreseeable future.”

“Our focus is on having a incredible 2019 and we are looking forward to welcoming everyone back to Imagine,” Shearer said. “Obviously, we are always looking for the best options for Imagine, but for now we are at the Speedway and love the amenities it provides.”

An estimated 35,000 people per day came through the Hampton racetrack’s gates last September, making it one of the South’s largest festivals.

Bouckaert’s Farm is no stranger to hosting large events though.

The 8,000-acre property owned by Belgian Olympian Carl Bouckaert welcomed the Echo Music Project, CounterPoint, the Many Rivers festival and Tomorrowworld in previous years.

Those concerts didn’t occur without incident, however.

Many Rivers patrons flooded the festival’s Facebook page with complaints after sitting in traffic


# Connect [![build status](https://secure.travis-ci.org/senchalabs/connect.png)](http://travis-ci.org/senchalabs/connect)

  Connect is an extensible HTTP server framework for [node](http://nodejs.org), providing high performance "plugins" known as _middleware_.

 Connect is bundled with over _20_ commonly used middleware, including
 a logger, session support, cookie parser, and [more](http://senchalabs.github.com/connect). Be sure to view the 2.x [documentation](http://senchalabs.github.com/connect/).

```js
var connect = require('connect')
  , http = require('http');

var app = connect()
  .use(connect.favicon())
  .use(connect.logger('dev'))
  .use(connect.static('public'))
  .use(connect.directory('public'))
  .use(connect.cookieParser())
  .use(connect.session({ secret: 'my secret here' }))
  .use(function(req, res){
    res.end('Hello from Connect!\n');
  });

http.createServer(app).listen(3000);
```

## Middleware

  - [basicAuth](http://www.senchalabs.org/connect/basicAuth.html)
  - [bodyParser](http://www.senchalabs.org/connect/bodyParser.html)
  - [compress](http://www.senchalabs.org/connect/compress.html)
  - [cookieParser](http://www.senchalabs.org/connect/cookieParser.html)
  - [cookieSession](http://www.senchalabs.org/connect/cookieSession.html)
  - [csrf](http://www.senchalabs.org/connect/csrf.html)
  - [directory](http://www.senchalabs.org/connect/directory.html)
  - [errorHandler](http://www.senchalabs.org/connect/errorHandler.html)
  - [favicon](http://www.senchalabs.org/connect/favicon.html)
  - [json](http://www.senchalabs.org/connect/json.html)
  - [limit](http://www.senchalabs.org/connect/limit.html)
  - [logger](http://www.senchalabs.org/connect/logger.html)
  - [methodOverride](http://www.senchalabs.org/connect/methodOverride.html)
  - [multipart](http://www.senchalabs.org/connect/multipart.html)
have grown with the financial crisis, as the dollar has fared much better than its only possible convertible competitor, the euro. I do not find the concept of economic dominance very useful in reference to either China or the United States because economics is far from a zero-sum competition. But if I had to cast such a concept in concrete terms, I might find no better example than the U.S. role in the international financial system after the financial debacle of 2008. Despite the revelation that terrible policies and habits in the world's leading economy levied tremendous economic losses not only on the United States but on the rest of the world, public and private economic entities around the globe, including the Chinese government, still came to the


of Mao's desire to portray himself as a leader of the developing world, he rejected great power arms control agreements that limited the number of nuclear powers. Even after the PRC became the first developing country to produce deliverable nuclear weapons in the 1960s, China remained wary of international agreements that would deprive others of the right to develop such weapons. This partially explains the history of China's past nuclear cooperation with countries like Pakistan and Iran.

China came late to the realization that increasing the number of nuclear powers did not serve its own interest. And as its growing economy needed more energy, Beijing wanted increased access to more foreign civilian energy technology. So Beijing signed on to the Nonproliferation Treaty only in 1992, twenty-four years after itsParty elites and a deep cynicism in the Chinese population about the ethical virtues of their leadership. The stimulus package that Beijing injected into the Chinese economy unfortunately did more than sustain growth, it accelerated the maldistribution of capital to state-owned banks and state-owned firms, and in the process encouraged further corruption and overinvestment by local officials in real estate and infrastructure projects. To make matters worse, a shadow banking system formed in which local financial trusts loaned additional funds at higher than allowed interest rates so that their customers could finance their often already inflated debt.

President Xi Jinping's very public efforts to initiate economic market reforms and crack down on state-sector corruption in late 2013 seemed designed to address all of these problems at once. The Party


times simply requesting that the ADIZ be implemented carefully. But two strong statements were made, one diplomatic and the other physical. Diplomatically, the United States reminded China and Japan that it recognized Japan's administrative control over the islands and that the islands therefore fall under Article V of the U.S.–Japan Defense Treaty. In addition, soon after the ADIZ announcement, two unarmed American B-52s flew a publicly announced exercise off the Senkaku Islands, driving home the point that the United States would not be deterred from military operations in international waters or international airspace near China.

But public reports also suggest that the United States was sending restraining messages to Japan and Korea, particularly when Vice President Joe Biden visited Tokyo, Beijing, and Seoul in December 2013. Japanese leaders, who2010.

. Kevin Bacon, "Pentagon: 'Too Early' to Call China's J-20 a Stealth Fighter," Stripes Central, January 26, 2011.

. Tai-ming Cheung, quoted in Kathrin Hille, "China: Doing It All Yourself Has Its Drawbacks," Financial Times, July 7, 2012, http://www.ft.com/intl/cms/s/0/200c0ae8-b485-11e1-bb2e-00144feabdc0.html#axzzlzwAOLvm9.

. See Tai-ming Cheung, "What the J-20 Says About China's Defense Sector," China Real Time Report, January 13, 2011; see also Phillip C. Saunders and Joshua K. Wiseman, Buy, Build, or Steal: China's Quest for Advanced Military Aviation Technologies (Washington, DC: National Defense University Press, 2011).

. Zachary Fryer Biggs, "U.S. Military Goes on Cyber Offensive," Defense News, March 24, 2012, http://www.defensenews.com/article/20120324/DEFREG02/303240001/U-S-Military-Goes-Cyber-Offensive.

. "U.S. Cyber Offense 'Best in the World': NSA's Gen. Keith Alexander," Washington Times, August 26, 2013, http://www.washingtontimes.com/news/2013/aug/26/us-cyberwar-offense-best-world-nsas-gen-keith-alex/.

. Michael O'Hanlon, cited in Lieber, Power and Willpower, 133.

. G. John Ikenberry, Liberal


side of the non-toxic food source that is positioned against the structure or item can include a fastener surface such as but not limited to peel and stick tape, hook and loop fasteners, and the like, which allows the embodiments to be attached to various manmade and natural structures and items. Additionally, the embodiments can be attached by novel fastening arrangements using fasteners such as screws, nails, and stakes, and the like.
Additional embodiments can include removable caps that can be either screwed on, snapped, on, or hingedly attached to the top of the chamber to allow the contents of the chamber to be replenished without having to remove the entire embodiment from a preattached location.
Further objects and advantages of this invention will be apparent from the following detailedIt was hardly a secret, but Mississauga councillor Bonnie Crombie made it official Tuesday morning: She will try to fill the sizeable void being left by legendary Mayor Hazel McCallion.

Crombie registered for the mayoral race at Mississauga City Hall, promising three key things. “My platform is: how we move; grow responsibly; and how we thrive.”

Crombie, a former one term MP for Mississauga, joined council in 2011 after winning a by-election following her defeat in the federal election.

Her main challenger in the race is former city councillor, MPP and MP Steve Mahoney.

After Mahoney registered last week, Crombie, long rumoured to covet the mayor's seat, said he did not represent the “Mississauga of today.”

Mahoney countered with his own shot, suggesting Crombie spends all her time promoting herself instead of formulating


a true vision for Mississauga.

Crombie said a full platform is being developed and will be rolled out in coming weeks.

Meanwhile, Mississauga voters now have two established candidates faced with a significant task.

Part of McCallion’s legacy is a $1.5 billion infrastructuredeficit, after more than a decade of near-zero per cent tax increases prior to the current term. Chipping away at that deficit in recent years has meant average increases of more than 5 per cent on the Mississauga portion of the property bill. Meanwhile, dozens of projects in the once-flush city have gone unfunded because slowing growth has reduced revenues.

Crombie said she’s the right person to turn things around.

“Economic development will be a focus. It’s all about the innovation and knowledge economy, and harnessing the diverse skills of oursamples. Sample supports with 1536 test sites are also in use. The test sites with diameters of 0.8 to 3.0 millimeters can be identified in some embodiments with the aid of milled-in rings, whose sharp milled edges prevent the applied acids and solvents from flowing laterally away. The test sites can also take the form of hydrophilic areas in a hydrophobic environment.
The sample support can especially also contain small pins, around 2 millimeters in diameter, which are inset into the sample support so as to be flush with the surface. The pins can be individually loaded with microbes by direct contact with microcolonies on agar surfaces. This can greatly shorten the culturing times, as is disclosed in the patent application WO 2013/182648 A1 assigned to the Applicant. The


to the representation of a motion picture. Furthermore, since one disk for the conventional CDG system can contains only about 15 songs, a large number of such disks (approximately double) are required to match the capability of an LD system, which also increases the need for the above-mentioned disk-changing apparatus.
The computer karaoke apparatus utilizes a semiconductor memory device and stores song accompaniment data and lyrics data therein in the form of musical instrument digital interface (MIDI) data. Then, corresponding MIDI data is read out according to a song selection, and character data is displayed on a screen of the video display unit. Here, the song accompaniment data is output via an audio processor.
Such a computer karaoke apparatus records the song accompaniment data as MIDI data, differently from theSignificant differences between Yemenite and Egyptian STR profiles and the influence on frequency estimations in Arabs.
A population genetic study was performed on Yemenites using the set of nine short tandem repeat loci (STRs) D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. Analysis of the data revealed that all loci were in Hardy-Weinberg equilibrium and evidence of linkage equilibrium was found for only 1 out of 36 locus pairs. At seven loci the allelic distributions found in the Yemenite sample were significantly different from those found for an Arab population sample from Egypt. Nevertheless, we assume that the Yemenite database can be used for Arabs of unknown or foreign (non-Yemenite) origin in the absence of population-specific databases without exerting a significant bias on the biostatistical interpretation. In


Guys shoes can sometimes be a tough area to master, especially when you don’t want to wear your work shoes, and sneakers just won’t cut in. That’s the exact moment when your new Chukka Boots from Vans will come in handy. A style that can be dressed up or down, worn with pants or shorts and throughout the entire year, these will most likely solve all your footwear problems.former having more than 66,000 followers and the latter having more than 37,000.

Last month I met up with some friends in Houston at this place that served hot dogs with raunchy names. Good times. A post shared by Amber Rachdi (@amberrachdi) on Nov 4, 2017 at 5:25pm PDT

Considering Amber’s influence and popularity with the My 600-lb Life community, however, there is a pretty good chance that the now-stunning young lady will make another appearance on a follow-up episode of TLC’s hit reality TV show soon enough.

[Featured Image by Amber Rachdi/Instagram]


public String collect() {
            Properties agentProps = VMSupport.getAgentProperties();
            String localConnAddr = (String)agentProps.get(LOCAL_CONNECTOR_ADDRESS_PROP);
            if (localConnAddr != null || jmxServer != null) {
                addAgentStatus(true);
                appendConnections(localConnAddr);
            } else {
                addAgentStatus(false);
            }
 }
    }

    /*
     * This method is invoked by the VM to start the remote management agent
     * via jcmd ManagementAgent.start command.
     */
    private static synchronized void startRemoteManagementAgent(String args) throws Exception {
        if (jmxServer != null) {
            throw new RuntimeException(getText(INVALID_STATE, "Agent already started"));
        }

        try {
            Properties argProps = parseString(args);
            configProps =


doesn't allow to change ThreadContentionMonitoring, but user
            // can specify this property inside config file, so enable optional
            // monitoring functionality if this property is set
            final String enableThreadContentionMonitoring =
                    configProps.getProperty(ENABLE_THREAD_CONTENTION_MONITORING);

            if (enableThreadContentionMonitoring != null) {
                ManagementFactory.getThreadMXBean().
              }

    private static void startAgent(Properties props) throws Exception {
        String jmxremote = props.getProperty(JMXREMOTE);
        String jmxremotePort = props.getProperty(JMXREMOTE_PORT);

        // Enable optional monitoring functionality if requested
        final String enableThreadContentionMonitoring =
                props.getProperty(ENABLE_THREAD_CONTENTION_MONITORING);
        if (enableThreadContentionMonitoring != null) {
            ManagementFactory.getThreadMXBean().
                    setThreadContentionMonitoringEnabled(true);
        }


    startRemoteConnectorServer(jmxremotePort, props);
                    startDiscoveryService(props);
                }
                startLocalManagementAgent();
            }

        } catch (AgentConfigurationError e) {
            error(e);
        } catch (Exception e) {
            error(e);
        }
   }

    private static void startDiscoveryService(Properties props)
            throws IOException, JdpException {
        // Start discovery service if requested
        String discoveryPort = props.getProperty("com.sun.management.jdp.port");
        String discoveryAddress = props.getProperty("com.sun.management.jdp.address");
        String discoveryShouldStart = props.getProperty("com.sun.management.jmxremote.autodiscovery");

        // Decide whether we should start autodicovery service.
        // To start autodiscovery following conditions should be met:
        // autodiscovery==true OR (autodicovery==null AND jdp.port != NULL)

        boolean shouldStart = false;


You are looking within the ignore page working to have the ability to write a resume, and are additionally questioning whether or not you may need enough data to fill someone a part of paper to be able to record out ones skills and experience. Now you need to knuckle down in addition to write your paper! The following stage will need to have grow to be turned simpler by writingsguru review thorough preparation. Stick with your plan together with the circulate within your authoring consistent throughout. It’s from time to time preferable to not write your introduction in anticipation of having finished the rest for the paper because, at that stage, you can truly introduce are you aware the snooze of your respective report units you couldMulti-frequency forced oscillation technique using impulse oscillations: can it give mechanical information about the lung periphery?
Forced oscillation techniques (FOTs) using sine curved oscillatory waves are used for assessing the lung periphery, but measure only overall respiratory mechanics. Therefore, mathematical models of the respiratory system serve as vehicles to obtain detailed mechanics. Although the simplest model of respiratory mechanics is a simple 3-element series (RIC) model, the constant phase (CP) model is recently used for characterizing respiratory mechanics, which has the advantage of partitioning of respiratory mechanics into airway and tissue components. Meanwhile, FOTs using non-sine curved oscillatory waves are easily applied in patients with severe respiratory diseases because they do not require voluntary apnea. If the latter type of FOTs is as informative as the former, the question


step of which is catalysed by the enzyme cyclo-oxygenase. Two forms of the cyclo-oxygenase enzyme (COX-1 and COX-2) have been characterised. COX-1 is important in circumstances where prostaglandins have a protective effect such as gastric mucus production and renal blood flow maintenance. NSAIDs inhibit the synthesis of prostaglandins at 1 or more points in the endoperoxide pathway. Three mechanisms of inhibition of the biosynthetic enzymes have been proposed: (i) rapid, reversible competitive inhibition; (ii) irreversible, time-dependent inhibition; and (iii) rapid, reversible noncompetitive (free radical trapping) inhibition. In addition, there is evidence that NSAIDs have a central antinociceptive mechanism of action that augments the peripheral effect. This may involve inhibition of central nervous system prostaglandins or inhibition of excitatory amino acids or bradykinins. There is considerable variability in thewhat it was like to see Prince live is near-impossible

Describing what it was like to see Prince live is near-impossible; an inherently reductive exercise that at its very best can only give a vague impression of the full experience, but a number of thoughts ran through my head that first show. The impeccable tightness and interplay between the man and his band; the showmanship, as Prince peacocked across the stage in all his purple glory; and then the guitar work itself.

I’d grown up on the blues-infused rock of guys like Jimmy Page and Slash, a type of playing with a specific swagger and woozy, boozy expressiveness. Prince was a different type of guitarist entirely, moving effortlessly from the searing leads of "Let’s Go Crazy" to the funk licks


explain the drop in muscle T4 content in these animals. Concomitantly, D3 activities were significantly elevated in *M/O* DKO mice compared with respective levels in wild-type (WT) and *Mct8* KO animals, and a trend toward higher D3 activities was also observed in *Oatp1c1* KO mice. These findings point to distinct changes in skeletal muscle TH homeostasis in the absence of MCT8 and OATP1C1.

To investigate the functional consequences of this perturbed TH homeostasis in skeletal muscle we performed real-time qPCR (qPCR) analysis of TA muscle samples ([Figure 1](#fig1){ref-type="fig"}D). *D2* mRNA levels were largely in line with the enzymatic activities, whereas *D3* transcript levels were close to the detection limit and therefore did not reveal any significant alterations. Expression of *Hairless*, a gene positively regulated by TH, was strongly increased in[@bib40]).

Conditional *Mct8* mutant mice (C57BL/6 background) were obtained from the KOMP repository (*Slc16a2*^*tm1a*(KOMP)Wtsi^). Further information is provided in [Supplemental Information](#app2){ref-type="sec"}.

*Mct8* fl/fl mice were mated with *Oatp1c1* fl/fl mice and transgenic animals expressing a tamoxifen-inducible *Cre recombinase* driven by the *Pax7* promoter ([@bib31]). Detection of the *Pax7 CreERT2*/+ transgene was performed as stated elsewhere ([@bib31]). *Mct8* fl/fl, *Oatp1c1* fl/fl, *Pax7*-*CreERT2* mice were treated with tamoxifen to delete *Mct8* and *Oatp1c1* specifically in SCs (*M/O*-SC KO) as described previously ([@bib43]). *Mct8* fl/fl, *Oatp1c1* fl/fl mice negative for the *CreERT2* transgene and treated with tamoxifen served as controls. Genomic DNA obtained from tail biopsies, brain, and gastrocnemius muscle were subjected to PCR.

Mice were kept at constant temperature (22°C) on a 12 hr light, 12 hr dark cycle and were provided with standard laboratory


skills which are effectively planned for and developed across all subjects – so that those wider skills are being developed around subject-specific skills.

“Highly effective and regular marking ensures that all pupils know how well they are doing and what they need to do in order to make rapid and sustained progress. Best practice marking is when teachers involve the students in dialogue so that they are not just giving a grade and bland comments such as ‘good but provide more detail’.

“A more helpful approach would be a comment such as, ‘good inclusion of the causes of the First World War, but which of your points can be linked together to show the interaction between them?’ This requires the pupil to provide an answer underneath the teacher comment by4. Let u = 48 - 34. Is j equal to u?
True
Suppose -l = -1 - 0. Let d = 19 + -22. Let n be (8/(-5))/(6/d). Which is smaller: n or l?
n
Let z = 36 + -24. Suppose z*p + 28 = 19*p. Which is smaller: p or 5?
p
Let h = 72.49 + -72. Let d = h - 0.49. Do d and 14 have the same value?
False
Let z = -1113 + 1130.82. Let y = z - 18. Let m = y - -0.58. Which is greater: -1/2 or m?
m
Suppose 10*h + 545 - 5 = 0. Let c be h/(-12)*(-2)/3. Is c less than 1?
True
Let p(l) = l**3 + 10*l**2 - 8*l + 8. Suppose 4*v + 6*i + 19 = i, 7 = -2*v


Ac/Al, Ne/Al, HNe, and HAl), while the secondary axis of variation (explaining 20.6% of the overall variation) distinguished cluster 2 from cluster 3 (Fig. [4b](#Fig4){ref-type="fig"}).Fig. 4The rhizosphere microbial community structure was associated with the nodulation of *Bradyrhizobium* and *Sinorhizobium*.**a** Composition and clustering of bacterial microorganisms from different rhizosphere samples on the phylum level. **b** PCoA analysis based on Bray--Curtis distances of the rhizosphere microbiomes of soybean seedlings grown in soils shown in Fig. [3a](#Fig3){ref-type="fig"}; *n* = 40. Clustering significance was determined by Adonis (Pr(\>F) = 0.001). Acidic soil (Ac), neutral soil (Ne), alkaline soil(Al), acidic soil plus lime (Ac8) and neutral soil plus lime (Ne8), alkaline soil amended with 50% (w/w) acidic soil (Ac/Al) or neutral soil (Ne/Al) and heated acidic soil (HAc), neutral soil (HNe), alkaline soil (HAl). **c** Linear dis**c**riminant analysis (LDA)be beneficial for their growth. In addition, we found clear correlations in rhizocompartment microorganisms, especially in the rhizosphere, including the interaction between rhizobia and other rhizosphere taxa (Fig. [2b](#Fig2){ref-type="fig"}), which is in agreement with the study showing that bacterial subnetworks in both bulk soil and the rhizosphere were most influenced by soil pH in 51 soybean fields across China \[[@CR64]\]. Microbial networks reflect cooccurrence patterns and interactions among microorganisms, which may affect the composition of the microbial communities or the interaction between microorganisms and host plants.

Root nodules are the organs that house rhizobia and are the site of symbiotic nitrogen fixation. A previous study showed that the composition of nodule endophytes is plant species-specific; *Sinorhizobium* were the dominant rhizobia in alfalfa, while *Sinorhizobium* and *Bradyrhizobium* were the most abundant


[@CR68]\], however, the role of *Bacillus* in soybean nodulation remains unclear. Intriguingly, our data show that *B. cereus* group strains isolated from the saline--alkaline soil specifically promoted the growth of CCBAU45436 but inhibited the growth of USDA110 (Fig. [5a, b](#Fig5){ref-type="fig"} and Supplementary Fig. [S10](#MOESM12){ref-type="media"}), and we speculated that *Bacillus* may also affect the distribution of rhizobia in soil. Through simulation of saline--alkali conditions with sodium bicarbonate and sodium chloride, we found that with the increase in pH, the nodule number in CCBAU45436-inoculated plants also increased even though the nodules were small, which may also partially explain why *Sinorhizobium* were dominant under alkaline soil conditions. Similarly, under low Pi conditions, some rhizobia can also induce more and smaller nodules, because they are relatively more sensitive to stress \[[@CR69]\]. Under normal conditions,*Bacillus* did not affect the nodule number of either CCBAU45436- or USDA110-inoculated plants. However, *Bacillus* treatment restored the nodulation defects (mainly nodule number) of CCBAU45436-inoculated soybean plants under saline--alkali conditions (Fig. [5e](#Fig5){ref-type="fig"}) and affected *Sinorhizobium* colonization in nodules as well (Fig. [6](#Fig6){ref-type="fig"}). It has been widely reported that root-associated bacteria can alleviate the adverse effects of salinity and alkalinity stress on plants \[[@CR70], [@CR71]\], thus it is likely that these root-associated bacteria may be beneficial to the nodulation of those stress sensitive rhizobia in legumes. Cooperative and competitive microbial interactions are important selective forces driving complex microbial assemblages in different compartments for plant fitness \[[@CR72]\]. To the best of our knowledge, this study is the first to report the interactive relationship between *Bacillus* and rhizobia and the effect of *Bacillus*


is he just as uncertain about how he'll play?

"Zero," Bryant said. "There was before I came back the first time because I didn't know how my Achilles would respond to changing direction. The game in Memphis, I had a pretty good feel and felt like I was getting back to what I normally do. I feel pretty confident."

Bryant also voiced optimism for Bulls guard Derrick Rose, who remains sidelined with a right meniscus injury after spending all of last season rehabbing a torn ACL.

"It's unfortunate," Bryant said. "You have two options. One is to lay down and not do anything about it. The second is to get up and get to work. The second one is more appealing."

Bulls coach Tom Thibodeau, who will serve as an assistant forthe NBA All-Star ballot ended Monday night, and will likely feature Bryant as a starter.

"I've always looked forward toward playing in All-Star games and that's something that's a huge honor," Bryant said. "I haven't played (much) this year. Some of the younger guys that have been performing, doing extremely well and are All Star worthy should be the ones out there playing."

Bryant also voiced his dislike on how the NBA has become more of a "finesse" game and employs "small ball," a philosophy Bryant conceded Lakers coach Mike D'Antoni largely speaheaded.

"I like smash mouth old school basketball," Bryant said. "That's what I grew up watching. It's much less physical. Some of the flagrant fouls I see called nowadays makes me nauseous. You can't touch a guy without it


store and passed that to the Sekken constructor.
    require 'sekken'
    require 'httpclient'

    url = "https://bridgerinsighteu.lexisnexis.com/webservicesapi/9.0/xgservices.svc?wsdl"
    # this is the secure trust CA
    cert = "/etc/ssl/certs/stca.pem"

    http = HTTPClient.new
    http.ssl_config.cert_store.add_file cert

    client = Sekken.new(url, http)

Q:

Extending the application core

I'm working on a new type of navigation window. This new window (which I've called MultiNav) is intended to allow the user navigate through video, music and images in the same window, this window has three controls that allow the user to select to content type he wants to navigate.
Everything compiles, but I'm not able to link.  The reason is the project is not able to find the object code (*.o files) since I've not include my changes into the build process (./configure  make).
I can tell the project is autotools generated, but I can't find any of the files configure.ac or Makefile.am.
Questions:
1 - How can I include my code into Kodi/XBMC code distribution?
2 - Which are the files I've to edit to achive


wish to
    # wipe out the existing attachment but not save, use #clear.
    def destroy
      clear
      save
    end

    # Returns the name of the file as originally assigned, and lives in the
    # <attachment>_file_name attribute of the model.
    def original_filename
      instance_read(:file_name)
    end

    # Returns the size of the file as originally assigned, and lives in the
    # <attachment>_file_size attribute of the model.
    def size
      instance_read(:file_size) || (@queued_for_write[:original] && @queued_for_write[:original].size)
    end

    # Returnswill be removed from future versions. ' +
           'Use Paperclip.interpolates instead')
      Paperclip::Interpolations
    end

    # This method really shouldn't be called that often. It's expected use is
    # in the paperclip:refresh rake task and that's it. It will regenerate all
    # thumbnails forcefully, by reobtaining the original file and going through
    # the post-process again.
    def reprocess!(*style_args)
      new_original = Tempfile.new("paperclip-reprocess")
      new_original.binmode
      if old_original = to_file(:original)
        new_original.write( old_original.respond_to?(:get) ? old_original.get : old_original.read )


in numbers.

Smaller in size than a polecat, but larger than a weasel, the stoat is another aggressive little hunter in the open countryside.

Identification between stoats and weasels is not easy – made all the more confusing by the fact that here on the Isle of Man the stoat is often called “Weasel”. However, it can be distinguished from its smaller cousin by its larger ears (weasel’s ears are very small as a proportion of the head size) and the black tip to its tail.

As with the mountain hare, stoats should moult in autumn to an all white coat (the true ermine coat) for improved camouflage in the winters snow but here on the Isle of Man the stoats retain a dark brown winter coat, in the same wayperceptions of and judgments about matters in which moral evils are not actually present. Carl’s critics are all too happy to appear righteous, to make others think they’re standing up against racism. And yet, their zeal to denounce and sheer intellectual laziness betray that what really motivates them is an underlying will to punish. Or in other words, the pleasure they take in cruelty. Such pleasure is usually obscured by means of self-deception. Finally, there is the immense social value that results from this farce. Said David Hume: “Where ambition can be so happy as to cover its enterprises, even to the person himself, under the appearance of principle, it is the most incurable and inflexible of all human passions.”

I have argued that, like the dubious value academics


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just watch the road." "I can't see shit." "I saw you talking to a pretty girl." "She was nice." "Yeah, man, who was it?" "She was just a girl." "Okay." "So I've got to drop the van off." "Thanks, Stan." "We'll talk." "You've got all your stuff, I see." "That's right." "I take it you're not coming back." "I wouldn't come back if I was you." "Do you swear you didn't know?" "I swear." "So you didn't do the erasing?" "Of course not." "God, no." "And you never even suspected we were together?" "Once, maybe." "I was coming back from a job, and you were at his car, and I saw you two talking." "So I waved to you, and you giggled." "How did I look?" "You lookedthat grow, distribute, sell and test pot both in its raw state and in finished products like food items.
The measure was submitted to the Secretary of State on Thursday and still must be cleared by the attorney general before its supporters can begin gathering signatures. Backers hope that empowering a state body to monitor the industry would show the federal government that California is serious about keeping marijuana in the hands of residents who are authorized to use it. In October, the four U.S. attorneys based in the state announced a coordinated action to shutter pot clubs and growers they accused of acting as a front for drug dealers. "We think that this initiative will create a level playing ground that law enforcement will embrace because it creates