drug target. ASC strongly inhibits the phosphorylation of FAK, and treatment with a FAK inhibitor significantly suppresses cancer cell migration in the presence of ASC. In addition, ASC significantly decreased phosphorylation of JAK2/STAT3, cancer cell migration and nuclear translocation of STAT3. Taken together, these results suggest that ASC inhibits cell migration and invasion by blocking FAK and JAK/STAT signaling, resulting in reduced MMP-2 activity. J. Cell. Biochem. 119: 300-313, 2018. © 2017 Wiley Periodicals, Inc.In recent years meditation has managed to shirk its label as a hippie practice, rebranding itself and becoming more popular in the West than ever before. Endorsed by businesses and universities alike, they boast that it helps focus, reduces stress, and can actually make the user more content. But how do the claims of this (once spiritual) practice hold up under scientific scrutiny? Is there any evidence to support these benefits?

Whilst research into meditation has been ongoing since the 1950s, early studies were impractical and unreliable. It was only a decade ago that the University of Oregon published a report into the ability of meditation to reduce stress when used in the short-term. Forty undergraduate students were asked to meditate for twenty minute sessions over five consecutive days,


NEW YORK—Motorola just took the wraps off its newest flagship, the 2015 Moto X, in addition to a couple other phones. There's a new version of the Moto G and two Moto Xes, but only one Moto X is coming to the US. Internationally, Motorola calls the flagship the "Moto X Style," and the mid-range Moto X the "Moto X Play." In the US, there's only one Moto X model, so it's called the Moto X Pure Edition. We're just going to call it the "2015 Moto X."

We've long considered Motorola to be the best Android OEM, and with the new Moto X, the company seems to be making all the right moves. The Moto X is still running stock Android—Motorola wants to make experiences that "augment, not"36.53 GB"}, {"Metadata Space Used", "20.97 MB"}, {"Metadata Space Total", "2.147 GB"}, {"Metadata Space Available", "2.127 GB"}, {"Udev Sync Supported", "true"}, {"Deferred Removal Enabled", "false"}, {"Data loop file", "/var/lib/docker/devicemapper/devicemapper/data"}, {"Metadata loop file", "/var/lib/docker/devicemapper/devicemapper/metadata"}, {"Library Version", "1.02.115 (2016-01-25)"}, {"Thin Pool Minimum Free Space", "10.74GB"}},
	NFd:               19,
	HTTPProxy:         "",
	Driver:            "devicemapper",
	NGoroutines:       39,
	NCPU:              4,
	DockerRootDir:     "/var/lib/docker",
	NoProxy:           "",
	BridgeNfIP6tables: true,
	ServerVersion:     "17.09.0-ce",
}

var containerList = []types.Container{
	{
		ID:


in play," said Joe Gaylord, who was an aide to former House speaker Newt Gingrich (R-Ga.) and now heads Chesapeake Associates, a political consulting firm. "All of that means more dough."with startups and global brands to create graphics that captivate their audience and inspire action.

With over six years of inhouse and freelance graphic design experience, I have the knowledge and skills to deliver design solutions that meet the unique needs of your project.

As a full time freelancer I offer flexible support, whether you need me inhouse one day to a full week, or to work entirely remotely. My pricing structure is clear and concise, ensuring you get competitive rates.

I’m centrally based in the East Midlands and can offer onsite graphic design services all major locations including London, Manchester, Birmingham, Leeds, Sheffield and Nottingham.

“Matthew showed unbelievable passion from the outset and it felt like he was part of the company rather than someone being hired externally. Each task was


release had been “unauthorised”. Climate Audit’s Stephen McIntyre published an excellent thread breaking down how the document invalidates the OPCW’s claims which you can read by clicking here. Establishment narrative managers had a very difficult time spinning the fact that the OPCW had taken it upon itself to hide findings from the public which dissented from its official report on an incident which preceded an international act of war upon a sovereign nation, and all the implications that necessarily has for the legitimacy of the organization’s other work.

Throughout this time, critical thinkers like myself have been aggressively smeared as deranged conspiracy theorists, war crimes deniers and genocide deniers for expressing skepticism of the establishment-authorized narrative on Douma. Which takes us to today.

Panel sees evidence of "unacceptable practices" innot be available to all users, and may, upon 30 days notice, be terminated, modified, or offered under different terms. The content of this videogame is purely fictional, and is not intended to represent or depict any actual event, person, or entity. The makers and publishers of this videogame do not in any way endorse, condone or encourage engaging in any conduct depicted in this videogame. Unauthorized copying, reverse engineering, transmission, public performance, rental, pay for play, or circumvention of copy protection is strictly prohibited.

For information about online services, fees, restrictions, or software license terms that may apply to this game, please visit http://www.rockstargames.com.

Rockstar Games 622 Broadway, New York, NY 10012 © 2006-2013 Rockstar Games, Inc. Rockstar Games, the Rockstar Games , Grand Theft Auto, Grand Theft Auto


The present invention relates generally to surgical instruments and more particularly to implant holders and inserters for inserting implants into the body.
The spinal disk resides between adjacent vertebral bodies and allows for relative motion between the vertebrae in a healthy spine. With disease and/or degeneration, a spinal disk may become painful and/or mechanically insufficient warranting surgical fusion across the affected disk. Present methods of inserting a spinal implant or interbody spacer between adjacent vertebrae generally include the use of a holder and a secondary device for the delivery of the implant to the final location.you understand my problem..
Can anybody help me?
Here is the fragment class and xmlparser class of my application
gamesfragment.java

public class GamesFragment extends Fragment {
// All static variables
public static final String URL = "http://api.androidhive.info/pizza/?format=xml";
// XML node keys
static final String KEY_ITEM = "item"; // parent node
static final String KEY_ID = "id";
static final String KEY_NAME = "name";
static final String KEY_COST = "cost";
static final String KEY_DESC = "description";

@Override
public View onCreateView(LayoutInflater inflater, ViewGroup container,
        Bundle savedInstanceState) {

    View rootView = inflater.inflate(R.layout.fragment_games, container, false);
    setRetainInstance(true);
    ArrayList<HashMap<String, String>> menuItems = new ArrayList<HashMap<String, String>>();

    XMLParser parser = new XMLParser();
    String xml = parser.getXmlFromUrl(URL); // getting XML
    Document doc = parser.getDomElement(xml); // getting DOM


    // looping through all item nodes <item>
        for (int i = 0; i < nl.getLength(); i++) {
            // creating new HashMap
            HashMap<String, String> map = new HashMap<String, String>();
            Element e = (Element) nl.item(i);
            // adding each child node to HashMap key => value
            map.put(KEY_ID, parser1.getValue(e, KEY_ID));
            map.put(KEY_NAME, parser1.getValue(e, KEY_NAME));
  at android.view.Choreographer.doCallbacks(Choreographer.java:555)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.view.Choreographer.doFrame(Choreographer.java:525)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.view.Choreographer$FrameDisplayEventReceiver.run(Choreographer.java:711)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.os.Handler.handleCallback(Handler.java:615)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.os.Handler.dispatchMessage(Handler.java:92)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.os.Looper.loop(Looper.java:137)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.app.ActivityThread.main(ActivityThread.java:4802)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at java.lang.reflect.Method.invokeNative(Native Method)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at java.lang.reflect.Method.invoke(Method.java:511)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at com.android.internal.os.ZygoteInit$MethodAndArgsCaller.run(ZygoteInit.java:813)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at com.android.internal.os.ZygoteInit.main(ZygoteInit.java:580)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at de.robv.android.xposed.XposedBridge.main(XposedBridge.java:115)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at dalvik.system.NativeStart.main(Native Method)
04-07 18:23:37.234: E/AndroidRuntime(19673): FATAL EXCEPTION: main
04-07 18:23:37.234: E/AndroidRuntime(19673): android.os.NetworkOnMainThreadException
04-07 18:23:37.234: E/AndroidRuntime(19673):    at android.os.StrictMode$AndroidBlockGuardPolicy.onNetwork(StrictMode.java:1117)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at java.net.InetAddress.lookupHostByName(InetAddress.java:414)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at java.net.InetAddress.getAllByNameImpl(InetAddress.java:249)
04-07 18:23:37.234: E/AndroidRuntime(19673):    at java.net.InetAddress.getAllByName(InetAddress.java:227)
04-07 18:23:37.234: E/AndroidRuntime(19673):


in this area also involves photoelectron-photoion coincidence (PEPICO) and threshold photoelectron-photoion coincidence (TPEPICO) spectroscopy, these methods are also described and previous related work on reactive intermediates with these techniques is summarised. The advantages of using PEPICO and TPEPICO to complement and extend TPES and angularly resolved PES and CIS studies on reactive intermediates are highlighted.As far as I am concerned this is the best camp for game viewing but could not get any late bookings for the 19/5/07 to 26/5/07. Instead i will be camping at Malelane(first time) and Crocodile Bridge(my 2nd favourite camp.

Satara is my favourite camp, game-wise. Two idyllic holidays there as a kid in the 80s. On both occasions spent a week or more in a caravan. The camping area used to be a massive lush 'field' on the north side, was sad to see it had been left to become so arid, on our last visit (stopped there for lunch). But apparently this was the new policy, that camp grounds would be left to become more 'natural'.

As kids do, we hooked up with similar aged kids, and played


it is an improvement as you will not have anyone camping outside you tent or van like we had 2x last year.
7.Finally, they have altered the ironing slab to be smooth in the newest ablution block(top right corner) as last year it was only for crinkled clothes
I hope this is good news for all.

A quick note about camping at Satara.All sites are now demarcated but they are not allocated so it is still first come first serve. The sites are very big and you can still get the occasion where two parties camp on one site. They are big enough so this is not a problem. The problem comes in with the power. There is one power point in the centre of 4 sites. There are 5 plugsand blacks have struggled for since the 1960s. His race isn’t a non-issue to white voters; they eagerly voted for a black man hoping his election would take our country to the next level in racial equality. Of course many voters also believed he would help us create a more balanced government, lead us out of the quagmires in the Middle East and redirect national priorities toward productive domestic initiatives. That’s certainly not the way it’s turned out so far.

Should we stop celebrating Black History Month now that we’re “post racial?” Heck no. A black president is a great role model, but too many racial problems still exist and will continue to exist in the future. We need to continue to shine the light and improve racial equity


in our country.

What should we do about the ongoing problem of AA religious cultures oppressing LGBT members of our communities? I suggest establishing a LGBTX History Week during the month of February, with an emphasis on AA queers who worked for racial equality. Then repeat that week’s race-related events, articles and activities throughout the Gay History Month in October. What better way to bring to light the great Americans who have struggled for equality as they experienced double oppression!

Wellness

Carole Bartolotto: The problem with concluding that GMOs are safe is that the argument for their safety rests solely on animal studies. These studies are offered as evidence that the debate over GMOs is over. Nothing could be further from the truth.

Environmentalism

Walker Foley: Elected officials seem to think there’s onlyThe one who overcomes the world believes that Jesus is the Son of God (5:6). John uses the full title of Jesus as the “Son of God.” He has described Jesus and the Father throughout the letter. In 1:3 our fellowship is with God the Father and with “Jesus Christ his son.” In the previous paragraph John stated the Father has sent the Son to be the savior of the world and that God will abide only those who acknowledge Jesus as the Son of God (4:13-16).

But there is a bit of controversy over the text of 1 John 5:7. Compare the KJV with any modern translation” The KJV reads “testify in heaven: the Father, the Word and the Holy Spirit, and these three are one.” These words


He's been tied to narco-terrorism, al-Qaida, the Taliban and widespread corruption. Now, Hugo Chavez appears on national TV pleading with Jesus to heal his cancer that has defied Cuban doctors.

maybe he should have thought about all his unchristian like acts he has imposed on others. a cry too late?? although we all know the Lord will listen but maybe not in the way he thinks it should be God Bless us All

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EmailQ:

Adding Bearer token to cookie after web api authentication

Inside my MVC Core app i am getting the user to sign into Azure through the below configuration
public void Configure(string name, OpenIdConnectOptions options) {
                options.ClientId = _azureOptions.ClientId;
                options.Authority = _azureOptions.Authority;
                options.UseTokenLifetime = true;
                options.CallbackPath = _azureOptions.CallbackPath;
                options.RequireHttpsMetadata = false;


         options.ClientSecret = _azureOptions.ClientSecret;
                options.Resource = "https://graph.microsoft.com"; // AAD graph
                options.SaveTokens = true;
                // Without overriding the response type (which by default is id_token), the OnAuthorizationCodeReceived event is not called.
                // but instead OnTokenValidated event is called. Here we request both so that OnTokenValidated is called first which
           Audit of cervical cancer screening and colposcopy attendance in rural South Africa.
Women in developing countries generally lack access to cervical cancer preventive services. An audit was performed in rural South Africa to test the hypothesis that women do not follow (pre-)cancerous cervical disease treatment sufficiently, to understand the possible reasons for this non-attendance behavior, and to evaluate other published diagnostic and treatment initiatives. Based on Pap smear and colposcopy attendance data, including age, HIV status, month of attendance, and cervical intraepithelial neoplasia (CIN) staging, relatively few patients (54% of 928 patients) visited a colposcopy clinic following an abnormal Pap smear. Although these co-factors do not explain this high non-attendance rate, HIV status was an important co-factor; percentage-wise, HIV positivity correlated with a higher attendance rate. Screening methods that


   app.CurrentTool = cmdItem;
}

Which uses the UID/CLSID of the command to identify it. To my knowledge Python tools don't have CLSIDs so you can't invoke them this way. Tools written in .net have CLSIDs embedded in them at creation so are subject to this method.
It is possible to use ArcObjects in python, there's a basic discourse here and a more complete post Accessing ArcObjects from Python?. If you can find a way to associate a CLSID/UID with the tool then it is possible.

to become a classy presence at the back. Crystal Palace loanee Ryan Inniss has recently joined and helped increase Port Vale’s defensive stinginess. And they have Carl Dickinson to circumnavigate.

Port Vale are in decent form at the moment and have the motivation of keeping themselves in contention for the play-offs by winning this game. Whilst many are looking at this fixture as a relatively easy game for Tony Mowbray to open his account with the club, we will need to find our way past a well-organised and street-smart Port Vale side. Rob Page’s side might be very happy to play large portions of this game on the back-foot and hurt us on the counter with their pace out wide, we need to make the spells we do dominate


factor of 1312 and 5986?
82
What is the highest common factor of 9864 and 324?
36
Calculate the greatest common factor of 159309 and 5022.
279
What is the greatest common factor of 26954 and 2?
2
What is the highest common factor of 1084923 and 119?
119
What is the highest common divisor of 1185445 and 15?
5
What is the greatest common factor of 15833 and 142?
71
Calculate the highest common divisor of 24 and 420996.
12
What is the highest common factor of 1721267 and 2774?
1387
What is the highest common factor of 340 and 525436?
68
What is the greatest common divisor of 495 and 33905?
5
What is the greatest common factor of 2600 and 1820?
260
Calculate the highest common divisor of 1105 and 3057535.
1105
What is the highest common divisor of 532060 and 1628?
148
What is the greatest common divisor of 1206 and 31088?
134
Calculate   int i = 0;

    while(plain_str[i] != '\0') {
        if((plain_str[i]+3) >= 0 && (plain_str[i]+3) <= 127) {
            cipher_str[i] = plain_str[i] + 3;
        } else {
            cipher_str[i] = plain_str[i] - 124;
        }
        i++;
    }
    printf("%s\n", cipher_str);
}

void decipher(char cipher_str[], char decipher_str[]) {
    //asdf
}

A:

The %s operator in scanf only reads a single word, not a whole line. So if you enter ab cd, only ab is put


Q:

Why are wait, notify and notifyAll methods of the class Object?

Is there are reason why these methods belong to java.lang.Object?
Since these methods are declared in java.lang.Object every class will inherited them.
That means that classes like String, ArrayList, etc. will also have them.
Doesn't that contradict the single responsibility principle?

IMPORTANT NOTICE: I am not asking:

Why these methods are not part of Thread
Why every object can be locked

A:

The fact that methods are inherited does not violate the Single Responsibility Principle. It could potentially violate the SRP if those methods could be overridden. But they cannot, they are declared final.
The SRP defines reponsibility

In the context of the Single Responsibility Principle (SRP) we define
  a responsibility to be “a reason for change.” If you can think of more
  thanallowed to create projects from Github
    # user repos.
    def allow_users?
      allow_users.is_a?(Array) ? !allow_users.empty? : allow_users
    end

    # Returns a Boolean true if the given username is allowed to create projects
    # from their own Github repos.
    def allow_users_include?(username)
      allow_users.is_a?(Array) ? allow_users.include?(username) : allow_users?
    end

    def allow_organizations
      if @allow_organizations.is_a?(String) || @allow_organizations.is_a?(Symbol)
        [@allow_organizations.to_s]
      else
        @allow_organizations.is_a?(Array) ? @allow_organizations.map(&:to_s) : @allow_organizations


San Diego County beaches earned high marks for water quality

North County Times wire services -

SANTA MONICA - San Diego County beaches earned high marks for
water quality over the summer, the environmental group Heal the Bay
reported today.

Heal the Bay assigned letter grades ranging from A to F to 494
beaches along the California coast, based on bacteria pollution
levels detected at monitoring stations from Memorial Day through
Labor Day.

The group's summer beach report card showed that 99 percent of
beaches in San Diego County received A or B grades.

The only beach that was found to need improvement was Pacific
Beach Point, which received a D.

In Orange County, a total of 96 out of 104 beaches received A
grades. The group noted that Doheny Beach, which is usually one of
the most polluted in the state, showedb(v) = -5*v - 2. Let r(y) = -5*b(y) + 4*g(y). What is the first derivative of r(s) wrt s?
1
Let l(j) be the second derivative of -j**4/6 - 3*j**2/2 + 7*j. Find the first derivative of l(k) wrt k.
-4*k
Let m(r) = -r + 1. Let f be m(3). Let u be (f/3)/(2/(-6)). What is the second derivative of 4 - 8*s - s**u - 4 + 6*s wrt s?
-2
Find the first derivative of 45*u**3 + 14 + 31*u**3 - 58*u**3 wrt u.
54*u**2
Let x(r) be the first derivative of 1/6*r**4 + 1/2*r**3 + 0*r**2 + 2 - 3*r. Let l(i) be the first derivative of x(i). Find the second derivative of l(y) wrt y.
4
Let a = 19 + -16. What is the second derivative of -273*d**3 + 7*d +


Ni below the limit of Ni, according to the regulations of the EU, but the other 3 pairs of earrings and the other metal alloys exceeded this limit. Overall, there is a close relation between the amount of Ni leached in the artificial sweat and the total content of Ni in the metal alloys, except for a few earrings. To our knowledge, this is the first study about the relation between the leaching amount of Ni and the total content of Ni in the metal alloys.

Next, to further examine the clinical relevance of the EU regulations for limiting Ni, we performed the Ni-patch test for the Korean patients who were sensitive to Ni because it is the most valuable clinical method used to define the thresholds for elicitingNo. 1-3, cheap earrings of unknown contents; No. 4-6, earrings of 14 K gold coated with white gold; No. 7-9, earrings of 14 K gold; No. 10-11, belt buckles; No. 12, hooks; No. 13-14, metal buttons.

Detection limit of the amount of leached Ni from metal alloys: \<0.1 µg/cm^2^/week. Detection limit of the Ni contents in metal alloys: 1 µg/g.

######

Results of patch testing with serial dilutions of nickel sulphate in petrolatum in 20 subjects after 96 hr

![](jkms-23-315-i002)

5% (10.4 mg/g of Ni), 1% (2.1 mg/g of Ni), 0.5% (1.04 mg/g of Ni), 0.1% (0.21 mg/g of Ni), 0.01% (0.021 mg/g of Ni), 0.001% (0.0021 mg/g of Ni), 0.0005% (0.00104 mg/g of Ni), 0.0001% (0.00021 mg/g of Ni), and 0.00005% (0.000104 mg/g of Ni). Subjects with atopic dermatitis: No 2,


set of all $\beta^I$ such that $I\subseteq R$ is homogeneous with $H(R/I)=\H$.

To understand ${\B}_{\H}$ for fixed $\H$, the first step is to show that this set has a sharp upper bound under the obvious component-wise partial order. This was accomplished independently by Bigatti [@Bigatti] and Hulett [@Hulett] in characteristic zero, and later by Pardue [@Pardue] in characteristic $p$. These authors showed that if $L$ is the lex ideal (guaranteed by Macaulay to exist) such that $H(R/L)=\H$, then $\beta^L$ is the unique largest element of ${\B}_{\H}$. Various other authors have asked if important subsets of $\B_{\H}$ also have unique upper bounds. For example, the Lex Plus Powers Conjecture of Evans and Charalambous [@MerminMurai] predicts that restricting $\B_{\H}$ to the Betti diagrams of quotients of ideals containing regular sequences inby $r$ is injective or surjective for all $i = 0, \dots, \ell(\H)$.

Harima actually proved that $\H$ is an SI-sequence if and only if there is a Artinian Gorenstein $k$-algebra with the weak Lefschetz property and Hilbert function $\H$.

Given an SI-sequence $\H$, we will abuse notation slightly by saying that an $R$-module $M$ has Hilbert function $\Delta H$ when we really mean that its Hilbert function equals $\Delta H$ for $d\le \lfloor\frac{\ell(\H)}{2}\rfloor$, and is zero otherwise.

The Gorenstein question was first considered in this context by Geramita, Harima, and Shin [@GHS:AM] in 2000. They demonstrated how to embed a standard $k$-configuration $\mathbb X$ (an iteratively defined sets of points in ${\mathbb P}^n$) in a so-called basic configuration ${\mathbb Z}$ (an intersection of unions of hyperplanes), and then showed that


we show that the quotient of $I_{c,t}(\H)$ (in the appropriate polynomial ring) is Cohen-Macaulay, and compute its dimension, Hilbert function, and graded Betti numbers. In §\[s:subideals\], we consider a special case of our procedure for manufacturing the $I_{c,t}(\H)$, and thereby construct a family of Gorenstein ideals $G_{c,t,s}\subseteq I_{c,t}(\H)$ for $s\ge 0$. Finally in §\[s:gorenstein\], given an SI-sequence $\H$ we form a Gorenstein ideal $J_c(\H)$ that has an Artinian reduction with the weak Lefschetz property, Hilbert function $\H$, and extremal graded Betti numbers. For $\H(1)\ge 2$, the procedure is to let $c=\H(1)$, $t=\ell(\Delta\H)$, $s=\ell(\H)-2t+1$, and then sum $I_{c-1,t}(\Delta\H)$ and its link with respect to $G_{c-1,t,s}$.

The main building block {#s:buildingblock}
=======================

At the heart of our construction is the decomposition of a Hilbert function into two $\mathcal O$-sequences as follows.

\[d:HF\] Given anR_{c-1,t}$, however, the multidegree of each minimal generator at each step of a minimal free resolution of $R/I_{c-1,t}(\H_c)$ must be zero with respect to $\omega_{c,t}$. It follows that the chain map induced by tensoring by $k$ must be zero.

Now consider the chain map induced by $R/\omega_{c,t}I_{c-1,t}(\H_c)\xrightarrow{\delta}
   R/\omega_{c,t}I_{c,t-1}(\H^c).$ Obviously if $\overline{1}$ is the generator of $R/\omega_{c,t}I_{c-1,t}(\H_c)$, then $\delta_0(\overline{1})$ is the generator of $R/\omega_{c,t}I_{c,t-1}(\H^c),$ so the mapping cone resolution is not minimal (between the zeroth and first step in degree $1$). For $j>1$, however, no cancellation can occur. Indeed, let $\alpha$ be the minimal exponent such that $\mu_2^\alpha\in L$ (we use here that $c>1$). Then $\beta^{L'}_{i,j}=0$ for $1<j<\alpha+i-1$, so $\beta^{\omega_{c,t}I_{c-1,t}(\H_c)}_{i,j}=0$ for $2<j<\alpha+i$ and it is enough to show that $\beta^{\omega_{c,t}I_{c,t-1}(\H^c)}_{i,j}=0$ for $j\ge \alpha+i$, i.e., that $\beta^{L:\mu_1}_{i,j}=0$ for $j\ge


$R/G_{c,t,s}$ (as is well known). But in the dimension zero case, $\ell(\Delta^{2t+s}H(R/G_{c,t,s}))=\ell(H(S))$ equals the socle degree of $S$ which is seen to be $2t+s$ by Theorem (\[t:Ggor\]).

A Gorenstein ideal with Hilbert function $\H$ {#s:gorenstein}
=============================================

We now have all the pieces required to define a Gorenstein ideal with Hilbert function $\H$.

Given an SI-sequence $\H$, let $c=H(1)$, $t=\ell(\Delta\H)$, and $s=\ell(\H)-2t+1$. If $c=0$, then $t=0$, $s=1$, and we let $J_0(\H)=0\subseteq R_{0,0,1}=k[z_0]$. If $c=1$, then $t=0$, $s\ge 2$, and we let $J_1(\H)=(z_0\cdots z_{s-1})\subseteq k[x_0, z_0, \dots, z_{s-1}]$.

Finally, for $c\ge 2$, we let $J_c(\H)$ be the ideal of $R_{c,t,s}$ $$J_c(\H)= I_{c-1,t}(\Delta\H)+G_{c-1,t,s}:I_{c-1,t}(\Delta\H).$$

Recall the classic result of Peskine-Szpiro [@PeskineSzpiro].

\[t:PeskineSzpiro\] Let $G\subsetneq I$ be ideals of a ring $R$ such that $R/G$ is Gorenstein and $R/I$ is Cohen-Macaulay with $\dim(R/I)=d$. Then $R/(G:I)$ is Cohen-Macaulay with $\dim(R/(G:I))=d$. Additionally,for $j\le \lfloor\frac{2t+s-1}{2}\rfloor$, that is, that the Betti diagrams of $J$ and $L$ coincide in rows $0$ through $\lfloor\frac{2t+s-1}{2}\rfloor$. But this is immediate because $\lfloor\frac{2t+s-1}{2}\rfloor\le t+s-1$ and $(I)_\lambda= (J)_\lambda$ for $\lambda\le t+s-1$ (by Corollary (\[c:IandJ\])) while the graded Betti numbers of $I$ and $L$ coincide (by Theorem (\[t:IBN\])).

If $s=1$, then Corollaries (\[c:IctHHilbertfunction\]) and (\[c:IandJ\]) are only sufficient to show that $\beta^{J}_{i,i+j}= \beta^{L}_{i,i+j}$ for $j\le t-1$ and $\beta^{J}_{i,i+j}= \beta^{L}_{c-i,c-i+2t-j}$ for $j\ge t+1$ (the latter by symmetry). Thus it remains to show that $\beta^{J}_{i,i+t}=\beta^L_{i,i+t} +\beta^{L}_{c-i,c-i+t}$ for $i=0, \dots , c$.

To accomplish this recall (Theorem 11.3 in [@Stanley]) that for any homogeneous $M\subseteq S=k[\mu_1, \dots, \mu_c]$, $$(1-T)^c\sum_{d\in \N}H(S/M,d)T^d =\sum_{d=0}^c\sum_{j\in
    \N}(-1)^d\beta^{M}_{d,j}T^j .$$ It follows that fixing a Hilbert function determines the alternating sum of the graded Betti numbers along


overall turbine efficiency and longevity. As will be readily appreciated, the more thorough the mixture of fuel and air, the lower the likelihood of localized overheating.
With the forgoing issues in mind, it is the general object of the present invention to provide a precision counter-swirl combustor that provides a level of temperature uniformity presently unknown in the art. In particular, it is the general object of the present invention to provide a precision forward-mounted counter-swirl combustor that employs air jets equipped with chutes, which allow for a degree of temperature uniformity presently unknown in the art.Grandpa and with a pony ride from her sister.

There's a short build up between Halloween and Grace's birthday. The girls took the time to do some bonding. They took advantage of the unseasonably warm weather.

Also, between the excitement of Halloween and the build up to Grace's birthday, Christy earned a break. It was time Grace start doing some chores. So, Grace has started feeding Lydia. However, after only recently recovering from the 2008 Great Sprinkle Famine, we were deep into the 2008 Great Baby Food Famine. Again, Grace was acutely aware. Lydia was only allowed to repeatedly lick a spoon dipped in food.

Then, they returned to bonding with a little game of catch. Due to Lydia's admittedly poor coordination, Grace found eye protection. Lydia was willing to risk


apply to all reports on the page. To access these filters, click the filter icon in the top-right of the page.

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When a filter is applied, text describingto Animals® (ASPCA®) was the first humane society to be established in North America and is today one of the largest in the world. They believe that animals are entitled to kind and respectful treatment at the hands of humans, as do we. As an official supporter, we stand with the ASPCA in the quest of a cruelty-free world where animals are safe and happier. We have pledged to make a flat amount of donation to their mission to save animal lives across the country.

Customer Reviews

Received bag in allotted time. Couldn't be happier with the service. Thank you!

2015-09-08 04:00:00 UTC

Megan P. said:
Beautifully Designed and Made

I am absolutely in love with this clutch! The quality is beautiful and the design is right on point. I also love how saturated


resuspended in Medium 154 and human melanocyte growth supplement (Cascade Biologics, Portland, OR, USA). During the primary culture of human melanocytes, 200 µg/ml of G418 (geneticin sulfate, Duchefa, Haarlem, The Netherlands) was added to the growth medium to suppress the proliferation of fibroblasts[@B9]. Primary dermal fibroblasts were obtained by the explant culture method, and maintained in Dulbecco\'s modified Eagle\'s medium (DMEM) supplemented with 10% fetal bovine serum (Invitrogen).

cDNA microarray
---------------

Total RNA samples were extracted using RNeasy Mini Kits (Qiagen, Hilden, Germany) according to the recommended protocol. The quality of all RNA samples was evaluated using agarose gel electrophoresis. Keratinocytes, melanocytes and fibroblasts were primary cultured from five foreskin specimens. Total RNAs were extracted, pooled to reduce the individual variations, and then used for cDNA microarray. For cDNA microarray analysis,of β-catenin increases, allowing its translocation to the nucleus and facilitates the activation of genes by Tcf/Lef transcription factors. A key target of Tcf/Lef/β-catenin in early melanocyte precursors is MITF[@B43],[@B44]. Therefore, we speculate that a high expression of Dvl is required for proper specification of melanocytes.

In summary, we compared the gene expression profiles between keratinocytes, melanocytes and fibroblasts. We found many novel signature genes for each cell type, the functions of which have not yet been reported. Although the precise functional roles of such genes remain to be determined, our data add new information on which to base further investigation into the regulatory mechanism underlying the specification of skin cells.

This study was supported by a grant from the Korea Health 21 R&D Project, Ministry of Health & Welfare,


11/28/2014.
 */
public class ToolbarFragment extends Fragment {

    ToolSelectionListener mCallback;

    public interface ToolSelectionListener {
        public void sendNewValue(int newValue);
    }

    public void clicked(ImageButton imageButton) {
        mCallback.sendNewValue(imageButton.getId());
    }

    @Override
    public void onAttach(Activity activity) {
        super.onAttach(activity);
    }

    @Override
    public View onCreateView(LayoutInflater inflater, ViewGroup container, Bundle savedInstanceState) {
        return inflater.inflate(R.layout.fragment_toolbar, container, false);
    }

    private ImageButton pencilButton = (ImageButton) getActivity().findViewById(R.id.pencil);
    private ImageButton eraserButton = (ImageButton) getActivity().findViewById(R.id.eraser);

}

DrawingFragment.java
package com.example.chris.drawingtest;

importnew trails as part of the company's Women's Evolution. This book will be the ultimate look at a once-in-a-generation business success story, as well as a mirror that reflects the cultural, social and political mores of our time.

Vince McMahon, WWE Chairman & CEO, says, "This will be an unapologetic look at the good, the bad and the ugly, and the journey that made WWE into the global phenomenon it is today."

Marks and Tannenbaum's previous oral history, "I Want My MTV: The Uncensored Story of the Music Video Revolution," was named one of the best books of 2011 by NPR, USA Today, CNBC, Pitchfork, Rolling Stone, The Atlantic, The Onion, The Huffington Post and many others. A24 is currently developing the book as a movie.

Carrie Thornton, VP and Editorial


may include other devices such as elliptical machines.
The cam is secured to the exercise machine and includes a channel therein. The channel may be annular or may be of another geometry where a different path of travel is desired.
The cam also includes a hole for the shaft of the exercise machine to extend through This hole may be eccentric from the center point of the channel or concentric.
The arm includes the pedal or other force applying member of the exercise machine. The cam follower engages the channel in the cam and travels therein. The cam follower is operable with the arm such that as the arm is driven by the face applied to the pedal or other such member, the arm drives the cam follower within the channel.
Athe plate.
The plate includes an eccentric hole to receive the shaft of the exercise machine. A hub is fixed to the shaft and capable of rotation therewith. The arm, cam follower and rods are configured as described above with regard to the first and second preferred embodiment with the exception that the cam follower is fixed within a hole in the ring. In this embodiment, the cam follower rotates the ring around the plate. The fact that the hole in the plate is eccentric causes the distance between the hole and the hole in the ring to change as the ring rotates around the plate. This distance change causes the rods to reciprocate within either the hub or the arm depending upon which includes the channels.
It is an


5 Simple Techniques For what is a medigap plan

5 Simple Techniques For what is a medigap plan

Should you rely upon pricey prescriptions to maintain your overall health, you should be selected that you locate the insurance company Together with the best Part D for your requirements. This won't normally be the insurer with The most affordable prices and finest reviews for Medigap plan G.

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Depending on the point out that you just reside in, you might not be capable of get Medicare Complement coverage in case you’re below 65 and have Medicare because of disability, conclude-phase renal condition, oramyotrophic lateral sclerosis.

Media planning is usually outsourced to some media company and involves sourcing and selecting best media platforms to get a customer's brand name or product to use. The task of media planning is to ascertain the top mix of media to achieve the promoting campaign targets.

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Plan File covers anything covered by Plan C and in addition addresses any excess costs charged by a doctor or healthcare facility that Medicare isn't going to address.

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Q:

What happens if during a signal handling in UNIX, the same signal gets sent to the program?

Any ideas on this? Is there some kind of a signal queue, or does it get dropped?
While we are at this question, is it true that signal handlers should do as minimal work as possible?
I read somewhere that a signal handler should use a pipe and just write one byte to it, indicating what the program should do. Then somewhere else the program periodically checks the pipe, and dispatches based on byte in it. (I might have misunderstood it)
Thanks, Boda Cydo.

A:

To answer the second part of your question, "is it true that signal handlers should do as minimal work as possible?" the answer is yes, because there is a very minimal setthe mRNA levels of *Bmp6*, desmin, hepcidin, *Id1*, *Nramp1*, *Smad6*, *Smad7*, stabilin-1, *Tfr1*, *Tfr2*, and β-actin in the isolated hepatocytes, KC, SEC, HSC, total NPCs, as well as in whole liver tissues. The procedures for total RNA isolation and cDNA preparation were described previously [@pone.0060534-Zhang2]. qRT-PCR analysis was performed using mouse specific primers listed in [Table 1](#pone-0060534-t001){ref-type="table"}. The specific primers for rat *Bmp6* and β-actin were the same as described in our previous studies [@pone.0060534-Zhang1]. All primers were verified for linearity of amplification. The results for each gene of interest are expressed as the amount of mRNA relative to β-actin.

10.1371/journal.pone.0060534.t001

###### List of mouse-specific primers used for qRT-PCR analysis.

![](pone.0060534.t001){#pone-0060534-t001-1}

  Gene


News

Charles Russell Speechlys advises the Civica Group on the acquisition of Web Technologies Group

09 September 2015

Charles Russell Speechlys advises the Civica Group on the acquisition of Web Technologies Group

Charles Russell Speechlys has advised the Civica Group (an investee company of OMERS Private Equity) on its acquisition of Web Technologies Group (WTG), the software consultancy and services group.

Based in London, WTG specialises in planning, building and managing complex, secure web applications and digital services for government and other public sector clients. Customers include the Home Office, Ministry of Justice, Department of Health, Foreign and Commonwealth Office, Government Digital Service, the College of Policing and the National Crime Agency.

The company is helping to progress the Government’s digital strategy, including adoption of agile processes, it has an established position on G-CloudNobody, Nobody But... Juan

Nobody, Nobody But... Juan is a Philippine comedy film released on December 25, 2009 as an entry to the 2009 Metro Manila Film Festival. The title is a take on the Wonder Girls song "Nobody".

Plot
Nobody, nobody but...Juan tells the story of a U.S.-based senior citizen named Juan (Dolphy) who lives in a senior citizens' home run by his son (Eric Quizon) and daughter-in-law (G. Toengi). The home's staff consist of a "black man" and a "chinaman", revealed as 2 gay Filipino TNTs who adopted identities to evade Immigration officers. Juan's favorite pastime is watching Wowowee on The Filipino Channel, though he does not watch the show just for entertainment's sake. Beside wanting to connect with the Philippines that he dearly misses, Juan is lonesome for


ROAD TEST MOTORING
MAKES YOUR DAY
43
OCT/NOV 2010 THE ROAD AHEAD
Soft-top, drop-top, open-top -- call them
what you will, but in a departure from
our usual like-for-like comparo we spring
into spring with a look at what's new
and diverse in convertibles.
STORY BARRY GREEN | PHOTOS MARK HORSBURGH
raising
the roofof a fringe movement in the United States, but can the Passive House method change the way we build?

This film is playing as a part of...

2011
,
60 min.
Colorado Premiere! DOUBLE FEATURE INCLUDES both Biophilic Design and Passive Passion!
IN PARTNERSHIP WITH THE US PASSIVE HOUSE CONFERENCE
Friday, Sept. 28 @ 7pm
Reception to follow
Biophilic Design is an innovative way of designing the places where we live, work, and learn. ... more


for religious reasons. More than 81% of respondents are willing to donate an organ to a relative, while only 42.5% are willing to donate to a non-relative. However, the proportion of those willing to donate to a non-relative after their own death rises to 70.5%, but only 43.6% are willing to donate a heart. Approximately 58% of respondents would consent to the donation of a relative's organ after death. Of all survey respondents, only 59.7% believe that organ donation is regulated and 31.8% fear that the doctors will not try hard enough to save their lives if they consent to organ donation. Approximately 77% believe the heart is removed while the donor is alive; although, it should be noted that the same proportion of respondents thought they knewin organ supply. Public awareness can be raised through traditional and social media campaigns. Implementing an opt-in or opt-out strategy at the time of obtaining national identification cards or drivers licenses should help boost the pool of available donors, and has proven effective in other countries.[@ref5] An innovative national program in Spain has been met by a successful increase in the number of donor hearts, making it one of the world's leading nations for heart transplantations. The rate of heart transplantations in Spain has risen from 10 performed in 1984 to \>230 performed per year since 1992.[@ref14] Spain is the only country with a sustained increase in organ donation since 1990 and a rise from 550 organ donors in 1990 to 1546 in 2007.[@ref15] This success has been


attributed to optimizing processes for early identification of brain death, accurate referral of potential donors, use of hospital-based transplant coordinators to educate families on the importance of donation, a centralized single transplant waiting list, and implementation of quality assurance programs to monitor the patient's progress.[@ref15] Adopting some of these approaches in our region will surely help improve current transplantation programs.

There is a clear shift in the attitudes of the Saudi community towards organ transplantation, with the younger generation seemingly more accepting of change and who are willing to donate an organ once given sufficient information and reassurance of the processes. Further awareness is needed to stress the importance of organ donation in the region, and the impact this has on the survival of patients with debilitating diseases. Emphasisshould be placed on the concept of saving lives, which is recited in the Quran and is supported by the decree (Fatwa) of the Council of Senior Scholars (no. 99 dated 6/11/1402 A.H) granting permission for organ donation and transplantation.[@ref16] Future efforts should be directed towards increasing public awareness by dispelling current misconceptions about the organ donation process.

Study limitations {#sec2-2}
-----------------

The strength of our study is that it included several regions of the Kingdom of Saudi Arabia and a similar proportion of each gender. Although a wide range of age groups were involved, older age groups are not well represented which is a study limitation. This is the only study that specifically addresses the attitudes towards heart donation. The main limitation of our study is that data were collected


hardest handshake, we had a long chat and Danny revealed himself as one of the nicest people we have ever met. Without avoiding painful boxing puns, he knocked us out when he showed us that he had just downloaded our new single on his phone.

Matt with the set list
Look closely and you will see the set list from our weekend in Brisbane. We played two great shows at the Zoo which incidentally is one of our favourite places to play.

Queenscliff crowd shot
This is our drummer’s point of view at the Queenscliff music festival. We recovered from prior lethargy to power through a more than respectable set. So far 207 people have tagged themselves in the photo, it would be nice to collect the whole set.

Pineapple 4X and Panadol
Thisfascin expression in adult tumor-bearing animals accelerated tumor progression and led to formation of invasive adenocarcinoma. Altogether, our study shows that fascin can promote tumor progression in vivo, but also unravels an unexpected role of fascin in tumor initiation.


Metabolism and transportation pathways of GDP-fucose that are required for the O-fucosylation of Notch.
Notch is a single-pass transmembrane receptor that mediates the local cell-cell interactions necessary for many cell-fate decisions. The extra cellular domain of Notch contains a tandem array of epidermal growth factor-like (EGF-like) repeats. Some of these EGF-like repeats are O-fucosylated by protein O-fucosyltransferase 1 (O-fut1), which is essential for Notch signaling in Drosophila and mouse. This O-fucose is further modified by Fringe, a GlcNAc transferase and other glycosyltransferases (O-fut1 in Drosophila and Pofut1 in mouse), to form an O-linked tetrasaccharide, which modulates Notch's selective binding to its ligands.or ZmABCC4 can functionally transport C3G *in vitro*. More recently, it has been shown that the ABC transporter VvABCC1, is localized to the tonoplast of grape berry exocarp cells and is biochemically capable of co-transporting anthocyanidin 3-*O*-glucosides and GSH when heterologously expressed in yeast^[@CR26]^. The co-transport of GSH with bile acids, vincristine, and other drugs by a human ABCC transporter has also been previously demonstrated^[@CR27]--[@CR29]^.

Though it is well known that TT12 is a MATE transporter responsible for the transport of flavonoids into the seed coat endothelium of Arabidopsis seeds^[@CR16],[@CR17]^, and that TT12 can also transport anthocyanins when heterologously expressed in yeast^[@CR6],[@CR17]^, the transporter(s) involved in vacuolar sequestration of anthocyanins in the vegetative tissue of Arabidopsis has not been determined. This is critical since Arabidopsis can form a variety


by Arabidopsis vacuolar membrane-enriched vesicles. GSH (5 mM) and vanadate (VO~4~^−3^; 1 mM) were dissolved in water. Bafilomycin A~1~ (BafA1; 0.4 μM), glybenclamide (Glyb; 150 µM), and gramicidin D (GramD; 5 µM) were dissolved in DMSO. All assay mixtures contained equivalent amounts of DMSO. The C3G uptake in the presence of 3 mM MgATP (173 pmol min^−1^ mg^−1^) was used as the control value and set at 100%. Other values were normalized to the control value and are the means of three replicates ± SD. Asterisks indicate a statistically significant decrease from the control value. \*\*P \< 0.01. (**d**) Effect of C3G concentration on uptake into Arabidopsis vacuolar membrane-enriched vesicles. Uptake rates in the presence of 3 mM MgATP at each C3G concentration were corrected for uptake rates during assays performed in the absence of MgATP. Values shown arethe means of three replicates ± SD. Apparent *K*~*m*~ and *V*~*max*~ values were calculated as 0.55 mM and 1.5 nmol min^−1^ mg^−1^, respectively.

The HPLC retention time of C3G before addition to the uptake assay media (C3G standard) was 11.8 min (Fig. [3b](#Fig3){ref-type="fig"}). Following the uptake assays, the C3G that was washed off of the filters eluted as a single peak with the same HPLC retention time as the C3G standard (Fig. [3b](#Fig3){ref-type="fig"}). The retention time of C3G was the same regardless of whether or not the assay included MgATP (Fig. [3b](#Fig3){ref-type="fig"}). Therefore, C3G remained unaltered following uptake into the Arabidopsis vacuolar membrane-enriched vesicles.

Since the presence of MgATP resulted in an increase in the uptake of C3G by Arabidopsis vacuolar membrane-enriched vesicles, the next goal was to determine the mechanism of this uptake. Directly energized MgATP


(**a**). (**c**) Hydrogen bond interactions between AtABCC2 residues and ligands (C3G and GSH).Figure 9AtABCC2 mutants in C3G and GSH binding sites. (**a**) Protein expression of mutants relative to wild-type. The western blot (inset) is one of three individual replicates. The full-length blot is shown in Supplementary Fig. [S4](#MOESM1){ref-type="media"}. (**b**) C3G uptake in the absence of MgATP. Sites 1, 2 and 3 refer to residues making hydrogen bonds with both C3G and GSH, only C3G, and only GSH, respectively. (**c**) C3G uptake in the presence of 3 mM MgATP. (**d**) C3G uptake in the presence of 3 mM MgATP and 5 mM GSH. (**e**) C3G uptake ratio with/without 3 mM MgATP. (**f**) C3G uptake ratio with/without 5 mM GSH, in the presence of 3 mM MgATP (transport activation by GSH). Values shown are the means ofthree replicates ± SD.

Putative binding sites of L7G in AtABCC2 {#Sec9}
----------------------------------------

The Ligand docking of L7G to an AtABCC2 model based on PDB ID 5WUA showed that the L7G binding site spans both the C3G and GSH binding sites identified above (See Supplementary Fig. [S1](#MOESM1){ref-type="media"}). Thus, L7G and GSH cannot both bind to the active site simultaneously, consistent with the finding that AtABCC2 is not a flavone/GSH co-transporter.

Discussion {#Sec10}
==========

We demonstrate that the vacuolar membrane-enriched fraction from Arabidopsis cell cultures transports C3G in an MgATP-dependent manner. This transport was strongly inhibited by known inhibitors of ABC transporters and H^+^-antiporters, suggesting that both an ABC transporter and an H^+^-antiporter are involved in C3G transport. Surprisingly, in the presence of the ABC transporter inhibitors, the H^+^ antiporter-mediated uptake did not compensate for the inhibition of


membrane-enriched vesicles, it was of interest to determine which specific ABC protein might be involved. The vacuolar membrane of Arabidopsis contains 10 ABC subclass C members (AtABCC1-8, 10 and 14)^[@CR48]^ and the AtABCC proteins are the predominate ABC transporters localized to the vacuolar membrane^[@CR49]^. Within this group, AtABCC1 and 2 were the first plant ABCC transporters identified and are the best characterized in terms of their *in vitro* transport activity^[@CR31]--[@CR33],[@CR39],[@CR50],[@CR51]^. Interestingly, both were also thought to be capable of transporting the glutathione conjugate of C3G (C3G-GS)^[@CR31],[@CR32]^. However, these results were questioned since other investigators^[@CR10]^ were unable to replicate the chemical formation of the \[^3^H\]C3G-GS substrate. It was suggested that the severe chemical conditions (e.g. high pH, heat, long incubation time) used for the synthesis of \[^3^H\]C3G-GS from C3Gof C3G by Arabidopsis vacuolar membrane-enriched vesicles exhibited Michaelis-Menton-type saturation kinetics (K~m~ for C3G of 0.55 mM) as did the MgATP-dependent uptake of C3G in the presence of GSH by AtABCC2 expressed in yeast (K~m~ for C3G of 1.6 mM). Our calculations (see Supplementary Information) indicate that the cyanidin-type anthocyanin concentration can reach 34 µM in cells of Arabidopsis leaves under typical soil-grown conditions and 0.38 mM in the cytosol of leaf cells experiencing stress conditions. This cytosolic concentration under stress conditions begins to approach the K~m~ values for both AtABCC2 expressed in yeast and the vacuolar membrane-enriched vesicles. It should also be noted, that the cyanidin-type anthocyanins in Arabidopsis leaves are decorated with xylosyl, malonyl, coumaryl, and sinapoyl moieties^[@CR52]^. These naturally occurring cyanidin-type anthocyanins are the more likely natural substrates of


media^[@CR65]^ supplemented with tryptophan (32 µM).

Preparation of yeast membrane vesicles {#Sec15}
--------------------------------------

The preparation of yeast membrane vesicles for *in vitro* uptake experiments was performed essentially as describe previously^[@CR65]--[@CR68]^ with some modifications. AHC media with tryptophan (200 mL) was inoculated with a single yeast colony and incubated for 24 h at 30 °C with shaking (150 rpm). The 200 mL culture was then diluted to 1 liter with fresh AHC plus tryptophan medium and incubated 24 h with shaking at 30 °C. The cells were collected by centrifugation (1200 *g* for 10 min), washed twice with water, and suspended in 50 mL of 1.1 M sorbitol, 20 mM Tris-HCl (pH 7.6), 1 mM DTT containing 37 mg zymolyase 20 T. The suspension was incubated for 90 min at 30 °C with gentle shaking (75 rpm). The resulting spheroplasts were pelleted by centrifugation (1200 *g* for 10 min) and resuspended into 25 mL   test: /\.css$/,
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around '51 -'53. Rode a Bianchi.

Hello just been looking at your site. I was an apprentice at Napiers, Luton from 1951 to 57. I had 2 bikes made by Pop Hodge and his helpers - but had to file the "top quality" french cast lugs to a nice taper myself over 2 or 3 evenings. Pop also made me specify the tube lengths, crank height, angles, etc., etc. "if you are in engineering you should be able to do this" he said. There were two SKF employees helping him out in the evenings. My digs were only about 100 yards away so it was a pleasure to see work going on. He proudly showed me the seat tube transfer saying that his bike won the World Championship inabout 1922. The surround of the transfer was taken from a Swan Vestas matchbox that was always near to hand to keep his pipe alight. There was a photo on the wall showing Pop on a penny-farthing in an early race

Somewhere I have the receipt for one of the frames signed off "yours in sport" Albert J Hodge. Wish I still had the bikes.

As has been mentioned here, Britain still has class distinctions.Central London should have almost no cars, but it has many, because there is so much money there. In August rich people from the Middle East ship their expensive cars by air to drive in London, because they can. This *really* bothers the British-born elite :-) These same people are astonished that a lowly person on


have them all over the place. I hire people, they do a web site. It costs me $3." Getty Images Donald Trump's most controversial quotes On Barack Obama: "Obama is going to be out playing golf. He might be on one of my courses. I would invite him. I have the best courses in the world. I have one right next to the White House." PA Donald Trump's most controversial quotes On himself: "Love him or hate him, Trump is a man who is certain about what he wants and sets out to get it, no holds barred. Women find his power almost as much of a turn-on as his money." Getty Images Donald Trump's most controversial quotes On America: "The American Dream is dead. But if I          </if>
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are incorrectly predicted. True Negative $(T_{N})$ indicates the number of negative samples that are correctly predicted. False Negative $(F_{N})$ represents the number of negative samples that are incorrectly predicted. At the same time, the Receiver Operating Characteristic (ROC) curves and the Area Under a Curve (AUC) are also used as an evaluation index to assess the performance of the model \[[@B35-ijms-20-03511]\]. The workflow of the proposed model is shown in [Figure 1](#ijms-20-03511-f001){ref-type="fig"}.

2.2. Assessment of Prediction Ability {#sec2dot2-ijms-20-03511}
-------------------------------------

In order to obtain more accurate and reliable experimental results, we optimized two important parameters of the rotation forest classifier on three different datasets of *Yeast*, *Human*, and *H. pylori*. Through the grid search method, we get the number of the optimal feature subset $K$ of RF classifier is 10, and theon three datasets are [Figure 2](#ijms-20-03511-f002){ref-type="fig"}, [Figure 3](#ijms-20-03511-f003){ref-type="fig"} and [Figure 4](#ijms-20-03511-f004){ref-type="fig"}. Here, the X-axis indicates the false positive rate, while the Y-axis denotes the true positive rate. In order to better verify the feasibility of our method, AUC values are calculated on *Yeast*, *Human*, and *H. pylori* datasets and their average AUC values are 96.11%, 98.62%, and 92.69%, respectively.

2.3. Comparison with Support Vector Machine (SVM) Classifier {#sec2dot3-ijms-20-03511}
------------------------------------------------------------

To more clearly assess the impact of the RF classifier on model performance, we compare the results of RF classifier model with those of Support Vector Machine (SVM) classifier model on the same dataset. To be fair, the data fed into the two classifier models are identical, both of which have undergone numerical transformation and feature extraction. The LIBSVM tool package used


95.1      93.3     91.0
  AC + SVM                            89.3      94.0     79.2
  Our method                          96.21     94.77    92.70

LDA: Linear discriminant analysis; RoF: Rotation forest; RF: Random forest.

ijms-20-03511-t005_Table 5

######

Predicted results on four independent datasets.

  Species         Test Pairs   ACC (%)
  --------------- ------------of up to €135 (£121).

In the US on Monday, the White House issued guidelines as part of its "15 days to slow the virus" campaign. Chief among them is a ban on mass gatherings, with people told to avoid gathering in groups of more than 10, and to avoid bars, restaurants and unnecessary travel.

Australia, which has had relatively few cases so far, told Australians to come home from abroad and is weighing up stronger measures.

New cases in China, where the virus originated, have stayed low in recent days. The country confirmed 21 cases on Monday, 20 of which were people arriving from abroad.

South Korea, which was also hit early by the virus but has tested at a greater rate than any other country, had its third day running


milligrams are there in eleven quarters of a gram?
2750
What is 61/4 of a microsecond in nanoseconds?
15250
How many years are there in six fifths of a decade?
12
What is 2258.7411 hours in weeks?
13.4448875
What is 91684.24t in nanograms?
91684240000000000000
Convert 572.2225 millennia to years.
572222.5
What is 47.88156 millennia in years?
47881.56
What is 1664090.19 milliseconds in days?
0.019260303125
What is one quarter of a microgram in nanograms?
250
What is 1/4 of a millennium in months?
3000
How many millilitres are there in 0.0878217 litres?
87.8217
Convert 1602.43 millilitres to litres.
1.60243
What is 31/2 of a kilogram in grams?
15500
How many minutes are there in twenty-nine thirds of a week?
97440
How many months are there in 27/2 of a century?
16200
What is 13/8 of a second in milliseconds?
1625
Convert 5.751595 millilitres to litres.
0.005751595
What is seven halves of a microgram in nanograms?
3500
How many minutes are there in 7/3 of amicrometer in nanometers?
600
Convert 0.1795792 micrograms to kilograms.
0.0000000001795792
What is 34/5 of a second in milliseconds?
6800
What is eighteen fifths of a meter in millimeters?
3600
How many micrometers are there in 9/10 of a centimeter?
9000
How many meters are there in 9119.262cm?
91.19262
How many nanograms are there in 37/2 of a microgram?
18500
How many tonnes are there in 43421.55ng?
0.00000000004342155
How many tonnes are there in 1097.036 grams?
0.001097036
Convert 4.422389 litres to millilitres.
4422.389
What is 806516.9 grams in micrograms?
806516900000
How many seconds are there in seventeen quarters of a hour?
15300
Convert 6.1885926 seconds to hours.
0.0017190535
How many centuries are there in 5.999938 millennia?
59.99938
What is 3/10 of a litre in millilitres?
300
What is 876.9928m in micrometers?
876992800
What is 11/8 of a kilogram in grams?
1375
What is 3/8 of a day in minutes?
540
What is 521.94051 minutes in days?
0.3624586875
What is 683.438 years in millennia?
0.683438
What is 0.2345259g in nanograms?
234525900
What


Ever since the game CryptoKitties was released in November 2017, the concept of nonfungible token has been ingrained in the minds of developers and investors in the crypto community. However, 2019 has been the year that NFTs have gained mainstream attention. And it should come as no surprise that even huge, multinational companies are currently developing NFT projects.

Recently, Mirosoft’s blockchain-based cloud platform, Azure, released its own nonfungible tokens program called “Azure Heroes” with the aim of rewarding its developer community.

Azure Heroes

Through Azure Heroes, Microsoft is on a mission to empower technical practitioners of all backgrounds. With that as the objective, it has created a tool to inspire the community to learn, coach and build on Azure while promoting healthy and inclusive behavior.

Issuance and transactions of “Badger” collectibles willhas the reach and the gravitas to nurture acceptance of NFTs.”

How NFTs can create value for an enterprise

Essentially, the evolution of NFTs is heavily dependent on the underlying blockchain infrastructure. Optimizing for scalability and transaction speeds, for example, is anticipated to have a huge impact on the rate of development for the space. Besides this, the absence of accessibility when it comes to NFTs is a real problem that has yet to be solved, and the entry of big players like Microsoft can go a long way to help.

Enterprises can use NFTs for inventory management, where certain tokens can be combined with other tokens to represent an assembled product with multiple component parts. Another area where NFTs can find application in enterprises such as Microsoft is in licensing


PHP has write permission to this file.

Joeri said on 4 Jun, 2006:

“Share-alike protects you (and us!) from that when you release content like this, by ensuring that you yourself will still have the freedom to re-use any derivative works produced.”

Would this mean that if I reuse a texture from ED that the whole movie I made would (also) be for the foundation to use?
If so, then I’m not going to contribute any of my textures anymore.
I can’t, because my clients don’t want the project I do for them to belong to the blender foundation just because I gave one of my textures to the foundation.

fz said on 4 Jun, 2006:

Can you upload a new version of the dvd part rar 2, 3, 4 and 5 ? because they(green vertical line). Vertical lines show time at which the inhibitors were added. We observed the same behavior in each case for n ≥ 8 experiments. **(f)** Period of protrusion/Retraction cycles of lamellipodia in control conditions, with 50 μM ZCL (13 min), with 1μg/ml CT (13 min) and 500nm GSK (13 min). **(g)** Persistence length of lamellipodia in control conditions, with 50 μM ZCL (13 min), with 1μg/ml CT (13 min) and 500nm GSK (13 min). **(h)** Retrograde flow rate of lamellipodia in control conditions, with 50 μM ZCL (13 min), with 1μg/ml CT (13 min) and 500nm GSK (13 min). Student t-test showed that the data significantly differ from the control conditions, \*P\<0.05. Data represent mean ± SEM. **(i)** Quantification of Rac1-GTP level in DRG neurons in


control, 25 μM CK (after 2 min), 50 μM CK (after 2 min) and 50 μM CK (after 8 min) conditions. Student t-test showed that the data significantly differ from the control conditions, n = 8,\*\*P\<0.005. Data represent mean ± SEM.](pone.0146842.g002){#pone.0146842.g002}

The above results indicate that Rac1 could be behind the recovery of lamellipodia which were transiently retracted after Arp2/3 inhibition. However, the Rac1 inhibitor EHop-016 inhibits both Rac3 as well as Cdc42 above the concentration of 3μM\[[@pone.0146842.ref035]\]. Therefore, in order to examine the possible role of the Cdc42 pathway, we used ZCL as a selective inhibitor which is known to target the binding site of the Cdc42 guanine nucleotide exchange factor, intersectin (ITSN) and to hinder Cdc42 activation\[[@pone.0146842.ref037]\]. When 50μM ZCL was added lamellipodia did not show significantsignificance \*P\<0.005. Data represent mean ± SEM.](pone.0146842.g003){#pone.0146842.g003}

Lamellipodia of DRG treated with a moderate concentration of Rac1 and Arp2/3 inhibitors were able to pull and push a trapped bead, but with a lower force compared to the force observed in control conditions ([Table 1](#pone.0146842.t001){ref-type="table"}). In the lateral direction: in case of LP the lamellipodia force decreased by 30--40% with an increase in the inhibition of Rac1, however it decreased by 50--65% when Arp2/3 was inhibited compared to control conditions. The retractile force LR decreased by 40% when Rac1 was inhibited by 10μM EH, inhibition of Rac1 by 20 μM EH decreased the LR force more than 70% probably due to a decrease in the lamellipodia retrograde flow rate. The retractile force LR decreased by 65% when Arp2/3 was inhibited.


(third row), lateral retraction (fourth row) and vertical retraction (fifth row) respectively. The student t-test has shown that in all the cases, the data significantly differ with respect to control conditions, P\<0.05. Data represent mean ± SEM.

These results suggest that lamellipodia were not able to explore the surrounding environment with an equal force when Rac1 and Arp2/3 were inhibited when compared to control conditions. In addition, lamellipodia were not able to exert a larger force in the axial direction than in the lateral direction, when compared with the control conditions state.

The effect of Rac1 inhibitors on the rate of lamellipodia protrusion {#sec006}
--------------------------------------------------------------------

Lamellipodia in the presence of 10--20 μM EH exerted a lower force but were still able to extend. In order to measure their rate of protrusion, weof another specific inhibitor of Rac1, F56. Transiently retracted lamellipodia following partial Arp2/3 inhibition condition did recover also in the presence of the Cdc42 inhibitor, ZCL ([Fig 2D](#pone.0146842.g002){ref-type="fig"}). Transiently retracted lamellipodia following Arp2/3 inhibition did not recover when treated also with 100 μM F56.

The level of activated Rac1 following an exposure to 50 μM CK for 8 minutes significantly increased compared to what observed in control conditions, 25 μM CK(2 min) and 50 μM CK(2 min) ([Fig 2I](#pone.0146842.g002){ref-type="fig"}). These results indicate the specific role of Rac1 in the observed recovery of motility following partial inhibition of Arp2/3.

A possible mechanism could be mediated by the Integrin pathways. Jacquemet, G. *et al*. suggested that the engagement of integrin followed by filamin-A, IQGAP1 and RacGAP1 enrollment, deactivates Rac1\[[@pone.0146842.ref042]\]. Ilić, D. *et*


retrograde flow rate, were calculated by extracting these features from many kymographs and averaged over for statistical significance.

Algorithm II {#sec016}
------------

Lamellipodia not only show periodic motion of protrusion and retraction ([Fig 6C](#pone.0146842.g006){ref-type="fig"}) but, during retraction, they also lift up and ruffle. To study the axial motion of GC lamellipodia, image sequences taken at different heights i.e. 0, 1, 2...6 were acquired and analysed. Algorithm II was based on the theory of defocusing, in which a pixel is assumed to be in focus at a specific height when its intensity equalises with the background intensity of the image of that height \[[@pone.0146842.ref055]\]. The background intensity of the image for each height was computed as the median of pixel intensities of the image for that height. The number of pixels infocus at a specific height was obtained and normalized by dividing it by the total number of pixels in focus at all the given heights. In this way, the fraction of pixels of the lamellipodium in focus at different heights, was extracted and plotted against time ([Fig 6F](#pone.0146842.g006){ref-type="fig"}). In this manner it was possible to study the maximal height reached by the lamellipodia edge during retraction in different conditions. Usually lamellipodia lift up high around the maximal retraction, so, in our experiments, their cyclic motility could be characterized both by the kymograph and by the fractional height that was reached (Figs [2](#pone.0146842.g002){ref-type="fig"} and [6](#pone.0146842.g006){ref-type="fig"}).

In order to quantify the motility of filopodia, phase contrast time lapse image sequences acquired at height '0' were analyzed. An Imagej (Image processing and


generates the
 children function Nav() {

return (

{pages.map(page => {

return (

{page.text}

);

})}

);

}

To add a new page to our website, we just need to add a new object to the pages array & let React handle the rest!

Rendering Elements

As I’m sure you’ve seen throughout this article, when working with JSX we’re working with elements to render into our page. An element describes what you see on the screen:

const element =
Hello!
;

Multiple elements such as this when combined, will form components. We’ll be taking a detailed look at components in my next article!

Rendering our elements to the DOM

Typically, we’ll have a
 like so, in our HTML:

This is known as our DOM node. Everything inside of it is handled by React DOM.

And to render a React element intoOn the basis of the nuclear features and degree of mitotic activity, 2 neoplasms were classified as benign myoepitheliomas and 2 as myoepithelial carcinomas. Judging by the paucity of cases in the literature, myoepithelial neoplasms appear extremely rare in the vulvovaginal region with only 3 previous case reports of primary vulval tumors. As far as we are aware, this is the first description of a primary vaginal myoepithelial neoplasm. At these sites, myoepithelial tumors are liable to be misdiagnosed as a variety of other neoplasms because the pathologist may not think of the diagnosis. In reporting these cases, we discuss the criteria for diagnosis and the differential diagnosis.


can be found online.

I’ve been meaning to write this post but just haven’t had the time to do so. I’ve received several messages and emails asking me about fonts that I use on some of my design projects. I have a pretty large font collection. Some of them are paid, but a lot of them are free! First of all, I suggest investing in some of the best typefaces out there but I also suggest that you take advantage of the free resources that can be found online.

Anyway, I just want to share with you some of my favorite websites to obtain some high-quality typefaces that you can immediately start using on your projects. By the way, a lot of the free fonts on these sites can alsoa typeface family designed to enable the diverse ethnic groups around the world who use the Latin and Greek scripts to produce readable, high-quality publications. It supports a wide range of Latin-based alphabets and includes glyphs that correspond to all the Latin ranges of Unicode.

Gentium Basic and Gentium Book Basic are font families based on the original Gentium design, but with additional weights. The “Book” family is slightly heavier. Both families come with a complete regular, bold, italic and bold italic set of fonts. The supported character set, however, is much smaller than for the main Gentium fonts. These “Basic” fonts support only the Basic Latin and Latin-1 Supplement Unicode ranges, plus a selection of the more commonly used extended Latin characters, with miscellaneous diacritical marks, symbols and


additional symbols and complete punctuation. This typeface is considered a Trial Version, in which certain letterforms have been replaced. Available only for non-commercial use as .otf. The advanced version of the font can be purchased. This typeface is being released as a sort of “beta,” in which people might become accustomed to the typeface and also voice their opinions on its usability.

Luxi fonts are commonly found on free software operating systems, such as Linux. They are the default fonts in Red Hat’s Bluecurve theme. This family includes Luxi Sans, a family of four sans-serif fonts, Luxi Serif, a family of four serif fonts and Luxi Mono, a family of four monospace fonts. These fonts can be downloaded using OpenOffice.org’s FontOOo wizard. (via Chris Apalodimas)

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(main contractor), construction work was completed in September 2011. As part of the development, a rail tunnel was built under the A5 road to connect DIRFTII to the rail network via the original DIRFT railport.

DIRFTIII
A further 7.5 million sq.ft. extension, DIRFTIII,  was proposed for construction on the former Rugby radio station site to the northwest of the current development. The proposal also included a large area  of green space, named Lilbourne Meadows. The development is a joint venture between ProLogis and Rugby Radio Station Limited Partnership (RRSLP) (BT and Aviva). The DIRFTIII site would also be rail connected, with over  of warehousing over  of land plus a  HGV parking site. A related development is the Sustainable Urban Extension (SUE) built to the westusing dried velvet antler, 1 g of the ground velvet antler powder was mixed with 100 ml of water and placed into a shaking incubator for 24 h at 70 °C. The mixtures were centrifuged at 3000 × *g* for 20 min at 4 °C and filtered with Whatman filter paper to remove the residues.

Preparation of enzymatic hydrolysate of velvet antler
-----------------------------------------------------

Velvet antler enzymatic hydrolysis was performed according to the previously reported method (Ko et al., 2013\[[@R16]\]). Six gram of the ground dried velvet antler powder was homogenized with 600 ml of distilled water (pH 8.0) and 60 μl of Alcalase (Novo Nordisk, Bagsvaerd, Denmark) was added. Enzymatic hydrolysis was conducted for 24 h at 50 °C. As soon as the enzymatic reaction had been completed, the hydrolysate was


vivo* (Park and Cho, 2011\[[@R23]\]). Therefore, in the present study, we investigated the anti-inflammatory effect of VAAH *in vivo* using zebrafish model. Intracellular ROS generation can be detected using oxidation sensitive fluorescent probe dye, 2\',7\'-dichlorodihydrofluorescein diacetate (DCF-DA) as the substrate. DCF-DA exhibits no fluorescence without ROS and becomes fluorescent upon interaction with ROS (Handa et al., 2006\[[@R7]\]). Zebrafish incubated with LPS showed that generation of ROS is significantly higher relative to the non-LPS treated zebrafish (negative control). Pretreatment with VAAH before LPS administration showed a significantly reduced ROS generation (Figure 3[(Fig. 3)](#F3){ref-type="fig"}). This result suggests an inhibition of ROS generation by VAAH treatment. We also evaluated the inhibitory effect of VAAH on LPS-induced NO production in zebrafish by using the fluorescent probe dye diamino-fluorophore 4-amino-5-methylamino-2\',7\'-difluorofluorescein diacetate (DAF-FM DA).n be 9/(h/(-6)) - -4. Solve n*f - f = 20 for f.
4
Let x be ((924/(-352))/((-9)/12))/(7/4). Solve -346 = x*q - 358 for q.
6
Let w be 84/39 + -2 + (12 - 792/78). Suppose i + 2 = 4. Solve 0 = w*a - i - 0 for a.
1
Let m = 2068 - 2056. Let u(j) = j**2 - 5*j + 20. Let w be u(0). Solve -m*r = -7*r - w for r.
4
Let w(a) = 3*a**3 + a - 1. Let b be (-4 + 1)*(91/21 - 8). Suppose -b*s = -24*s + 13. Let g be w(s). Solve g*d + 10 = -5 for d.
-5
Suppose 9*h - 12*h - 33 = 0. Let v = h - -15. Suppose 9*t - v*t - 4 = 2*p,


Finance Minister Vic Fedeli spoke in the Ontario legislature about the province's fall economic statement on Thursday afternoon, calling it the "next step in our plan for the people."

Fedeli is set to answer questions about the economic statement in a news conference on Thursday afternoon.

The statement unveiled the PCs' short-term plans for spending restraint in the face of what Fedeli says is a $15-billion deficit inherited from the previous Liberal government.

You can read more about the contents of the statement here:

The fall economic statement, which includes spending cuts, some tax relief and a number of steps aimed at boosting affordability, is the first budget document unveiled under Premier Doug Ford.

As part of the economic statement, the PC's have announced a plan to cut the number of legislative officersfrom nine to six positions.

Previous reporting below.

Ontario Finance Minister Vic Fedeli is poised to eliminate at least two provincial watchdog positions on Thursday as the government of Premier Doug Ford launches its cost-cutting drive, CBC News has learned.

Fedeli is scheduled to deliver the fall economic statement, the first budget document under Ford, on Thursday.

It will unveil the PCs' short-term plans for spending restraint in the face of what Fedeli says is a $15-billion deficit inherited from the previous Liberal government.

Two offices facing cuts are those of the Environmental Commissioner of Ontario and the Ontario Child Advocate, according to government and PC party sources who spoke to CBC News. Both agencies are headed by independent officers who report to the legislature, rather than to the government, giving them an


patients reported using tetrahydrocannabinol-containing products in the three months before their symptoms started. But because the cause of EVALI is still unknown, the Centers for Disease Control and Prevention and Hawaii Department of Health officials recommend that people refrain from using all vaping products until the investigation completes.

In response, some major retailers have pulled products from their shelves.

Cory Lum/Civil Beat

Walmart announced Sept. 20 that it would stop selling e-cigarettes once its current inventory sells out, citing “growing federal, state and local regulatory complexity and uncertainty regarding e-cigarettes.”

Walgreens, which did acquire an ESD retailer certification from the state AG, announced Oct. 9 that it would stop selling e-cigarettes as well.

Civil Beat reached out to seven major e-cigarette retailers in Hawaii for comment, but did not receive a response.

Over theQ:

Transforming a string into a escaped char

The goal is to have a string input (coming from the frontend), and this string should be transformed to act as a escaped char in the backend.
In the following example I want the user to write "\" + "t", and the backend should interpret it as "\t" (= tab char):
    var inputStr = @"\t"; // The input is a string written by a user: "\t" (backslash char + t char == @"\t" != "\t")
    var outputStr = SomeOperation(inputStr); // ???
    Console.WriteLine("A" + outputStr + "B <= should be tab separated");

I have tried:
var outputStr = inputStr.Replace("\", "");

A:

I have finally found an easy way to do it:
Regex.Unescape(inputStr);

See the documentation of the Regex.Unescape function for


students a platform to train their clinical skills. They can practice various kinds of manipulating procedures repeatedly to become proficient in them. Issenberg identified that the most important factor in separating the elite performer from others is the amount of "deliberate practice" that an individual obtains[@b6]. Repetition of practice can help medical students achieve competency and confidence to perform the manual work well. Besides, through simulation training, they can have a deeper understanding of what they have learned from books. It helps to form medicos\' clinical thinking abilities.

Due to the training objective and the need of teaching, we have introduced many medical simulation models in our teaching programs. In diagnostics, we have obtained machines for complete blood count and urinalysis, microscopes, equipment for staining and so on. Inminus -17537347?
17537344
What is -0.0158 less than 238606?
238606.0158
What is -141604750 + 0.4?
-141604749.6
0.5+377025726
377025726.5
Calculate -55336 + -5897.
-61233
What is 3763189.2 + -0.081?
3763189.119
Total of -1600 and -1469819.
-1471419
0.0338 + 1468650.1
1468650.1338
What is -14643575 plus 11?
-14643564
What is -3.8 take away -114146843?
114146839.2
What is 2.6 - 703129467?
-703129464.4
Calculate -174 + -59701.
-59875
Work out -0.086681556 - -4.
3.913318444
What is 0.1 - 5434909494?
-5434909493.9
Calculate 12.453 + 99183.
99195.453
Work out -8347706 - 0.3.
-8347706.3
Work out 0.04 + -1920.66.
-1920.62
What is 0.4 take away 4052.1495?
-4051.7495
What is 473736 minus 0.56112?
473735.43888
What is -0.5 less than 424207535?
424207535.5
What is -5 minus 63282982?
-63282987
Calculate 401.333897 - -23.3.
424.633897
Work out -3.4 - -5665697.
5665693.6
Add together 1.4 and 13424672.
13424673.4
Sum -1 and 6482660.
6482659
Calculate 5.319 + 91235.
91240.319
What is the difference between 0 and -2538641905?
2538641905
Calculate -0.5 - -27836991.
27836990.5
What is -24023 plus -30.07?
-24053.07
What is -1644354 plus -4?
-1644358
What is 652 - 72534?
-71882
7475 + 924
8399
What is 13973954 + -33.8?
13973920.2
Total of -0.5 and -677394.66.
-677395.16
What is -4481947


Q:

What is the history of the university asylum law?

I fear this question may be rather broad and I would like help to narrow it down. Currently a debate is ongoing in Greece regarding the law preventing police from stepping into university campuses. The law was put in place after the fall of the military junta in 1974 which had violently suppressed a student rebellion. Such a protection was meant to safeguard students and freedom of speech. I was reading the New York Times article and the following claim was made at the end:

Odysseas Zoras, the top official of the University of Crete, said both academics and society were ready for an end to an antiquated concept, introduced in Bologna in the 11th century to avert the church’s interventiondeportment and good character."
The leniency of the punishments for grave moral offences, as contrasted with the strict insistance upon the lesser matters of the law, cannot fail to impress modern readers, but this is not a characteristic peculiar to Leipsic. Fines, and in the fifteenth and sixteenth centuries, whippings were frequently inflicted in all universities for violent attacks upon the person. Dr Rashdall quotes a case at Ingolstadt where a student who had killed another in a drunken bout was let off with the confiscation of his goods, and the penalty of expulsion was remitted ; and the eighteenth-century history of Corpus Christi College at Oxford supplies more recent instances of punish- ments which could scarcely be said to fit the crime.
  The statutes of


a privilege assuring them that he would prosecute with special rigour any persons doing them harm, and undertaking to allow scholars accused of criminal offences to be tried bythe ecclesiastical authorities.
Meanwhile in Bologna the universitas of scholars was gathering strength and becoming more firmly established, to the alarm of the commune, which feared the growth in its midst of a cosmopolitan body and a jurisdiction parallel to that of its own podestd. In 1211 the city was governed by the podesta Guglielmo da Pusterla, who supported the Emperor Otto IV recently excommunicated by Innocent III. One of the laws enacted by Guglielmo as podesta prohibited the formation of groups whose members swore to lend each other mutual aid and support, other than associations of men of warnon-generic return types.
So I would at least change it to:
public class ProfileCollection implements Iterable<Profile> {
    private ArrayList<Profile> m_Profiles;

    public Iterator<Profile> iterator() {
        Iterator<Profile> iprof = m_Profiles.iterator();
        return iprof;
    }

    ...

    public Profile GetActiveProfile() {
        return (Profile)m_Profiles.get(m_ActiveProfile);
    }
}

and this should work:
for (Profile profile : m_PC) {
    // do stuff
}

Without the type argument on Iterable, the iterator may be reduced to being type Object so only this will work:
for (Object profile : m_PC) {
    //


than 0.35566?
-1.64434
Put together 0.22 and -746.
-745.78
Calculate -3 - 2.856.
-5.856
3283245 - 5
3283240
What is the difference between -310348 and 2?
310350
Calculate 2595 + -4.
2591
What is the difference between -29 and 0.013?
29.013
Work out -464510 - -0.4.
-464509.6
What is -671734 - -0.2?
-671733.8
Work out -97 - 0.1709.
-97.1709
What is 0.2 plus -730?
-729.8
Work out -4 + 287341.
287337
Calculate -1 - 0.034213.
-1.034213
Total of -41 and -87.
-128
What is 6 minus 1.104?
4.896
Total of -23907 and -9.
-23916
-0.27 - 2926
-2926.27
What is 3038 less than 28?
-3010
Add 0.13 and -14564.
-14563.87
What is 1 + -5.744?
-4.744
Work out -3.7238 - -1.85.
-1.8738
519107 - -0.5
519107.5
What is 24338 minus 7?
24331
Add together -0.3673 and -81.
-81.3673
Sum -5 and 1168.765.
1163.765
Work out -554422 + 0.
-554422
Subtract -4 from -16.852.
-12.852
Calculate -4873 + -0.1.
-4873.1
636.415+-0.2
636.215
What is 0.04 plus -2861.1?
-2861.06
Work out 0.2 - -23967.2.
23967.4
What is 33.8 minus -0.27?
34.07
What is 0.4 - -5042?
5042.4
-121+0.1912
-120.8088
Add -0.2 and 21.38.
21.18
Add together 7.5 and 0.325.
7.825
What isThe present invention comprises a new Verbena, botanically known as Verbena hybrida, and hereinafter referred to by the variety name ‘VEAZ0053’.
‘VEAZ0053’ is a product of a planned breeding program. The new cultivar has medium sized inflorescences, medium sized flowers, that are bicolor, dark rose and pink, dark green, undivided leaves, and an upright plant habit.
‘VEAZ0053’ originated from a selfing made in July 2013 in the greenhouse in Enkhuizen, The Netherlands.
The female (and also male) parent was the patent applied plant designated ‘VEAZ0050’ application Ser. No. 16/350,008, having a flower color that is dark lavender with light lavender bicolor, medium sized leaves, and an upright plant habit.
The resulting seed was sown in February 2014 in a greenhouse in Enkhuizen, The Netherlands. ‘VEAZ0053’ was selected as one flowering plant within