 }

  /* documentation is in ftoutln.h */

  FT_EXPORT_DEF( FT_Orientation )
  FT_Outline_Get_Orientation( FT_Outline*  outline )
  {
    FT_BBox     cbox;
    FT_Int      xshift, yshift;
    FT_Vector*  points;
    FT_Vector   v_prev, v_cur;
    FT_Int      c, n, first;
    FT_Pos      area = 0;

    if ( !outline || outline->n_points <= 0 )
      return FT_ORIENTATION_TRUETYPE;

    /* We use the nonzero winding rule to find the orientation.       */
    /* Since glyph outlines behave much moreNick Stahl

A talented actor with a penchant for playing intense, often troubled young men, Nick Stahl garnered the respect of critics and his peers at a young age with a winning combination of independent and ma...
Read More...

Richie Buxo / Splash News
A great many actors have stepped up to play the ever-changing face of John Connor, but the upcoming Terminator reboot, Terminator: Genesis, may have just found its newest savior. According to Deadline, Jason Clarke is in talks to play John Connor, the fabled leader of the human resistance who is destined to save humanity from a sentient artificial intelligence.
If Clarke is chosen for the role, he would join the ranks of Edward Furlong, Nick Stahl, Christian Bale, and Thomas Dekker, who have previously portrayed the character in the


patterns.
The last film in the series, Terminator: Salvation, marked the second dud in a row for the franchise that has been plagued with recycled ideas and creative misdirection since its third film. The series has had trouble stopping itself from dipping into the well of worn ideas and repeating itself. Hopefully, director Alan Taylor (Thor: The Dark World) can breathe some much needed imagination into a series that hasn’t done much (besides the short-lived Sarah Connor Chronicles TV series) to justify its existence beyond its first two excellent entries. A good first step would be casting someone else as the Terminator instead of Schwarzenegger, but Arnold's return seems like an inevitability at this point. Maybe Hollywood can manage to produce a good Terminator film before our Roombas start2003-05). After his disturbing, but memorable supporting role in the hugely popular neo noir, "Sin City" (2005), Stahl worked steadily in such indie efforts as "How to Rob a Bank" (2008) and "388 Arletta Avenue" (2012). One of the edgier screen performers of his generation, Stahl continually made career choices based on his interest in the content of a project, rather than the size of its budget.<p>Born on Dec. 5, 1979 in Harlingen, TX, Nicolas Kent Stahl was the youngest of three children born to Donna Lynn and William Kent Stahl, who left the family when Nick was but two years old. When Lynn, a brokerage assistant, took her son to his first play at the age of four, it seemed to instantaneously set the course of his


setup, the robot will also allow extensive crystallization trials for projects that would otherwise not be possible. In addition, crystallization experiments will have a smaller impact on the environment by generating much less waste. The crystallization robot requested is the Screenmaker96+8 from Innovadyne - $145000. This robot can perform three distinct processes needed to set up crystallization experiments. Step 1: transfer of reservoir solutions from the sparse matrix stocks to the 96 positions in the crystallization tray;Step 2: deposition of nano-liter volumes of this reservoir onto the drop position and deposition of the protein nano-liter volume onto the same spot;Step 3: to refine the condition by making custom grids by varying two components in the lead condition to create new opportunities for improved crystal growth. Another very important[Risk factors related to the use of amphetamines in adolescent students].
The prevalence of amphetamine abuse among school children was studied by asking 3548 adolescent students (aged 12-15, response rate 98.6%) to complete a questionnaire anonymously, which was developed and evaluated by the authors. A complete set of data was collected for 3200 (90.2%) students. Eighty-five (2.7%) of them who admitted that they had used amphetamines constituted the case group. Non-users with negative urine tests formed the control group. Six independent factors were found to be related to amphetamine use when the answers were analyzed by stepwise logistic regression. The prevalence odds ratio estimation was elevated in: males compared females, students who did not live with both parents compared to those who lived with both parents, students with amphetamine-user


but his words will never be forgotten. ... Snape,
who was played wonderfully by Alan Rickman in the films. ... he is one the most
beloved characters within J.K. Rowling's book series. ... So here are 29 of the
most memorable Professor Snape quotes from the Harry Potter books.

Severus Snape was Potions Master, Defense Against the Dark Arts teacher, and
... Severus and Lily attended Hogwarts together from 1971 to 1978, but ..... The
walls were completely covered in books, most of them bound in old ... grouped
together in a pool of dim light cast by a candle-filled lamp hung from the ceiling.The Devil All the Time

Rating: 7.5 2020 138

The Devil's Due DVD / Blu-ray is a very good movie for you to watch if you want to watch movies that are available in high definition. It is a m…


Enjoy this Silk Scarf 100% made in France in the oldest manufacture in Lyon.The manufacturer creates and manufactures silk twill scarves in Lyon since 1890.They produce scarves and "carrés" for the best luxury French brands.

Simply unique !

This is an iconic Silk Twill Carré (Square). It is made of 100% silk twill. This beautiful scarf measures approximately 25"x 25". It has a

Beautiful French Parisian design "Blue polka dot". Its has a unique quality, it is made from the last real silk scarf manufacturer in France.

Enjoy this Silk Scarf 100% made in France in the oldest manufacture in Lyon.The manufacturer creates and manufactures silk twill scarves in Lyon since 1890.They produce scarves and "carrés" for the best luxury French brands.

Simply unique !

This is an iconic Silk Twill Carré (Square). ItJoshua said about Fury to BBC Radio 5 Live.

“He has his own battles and demons to face and, once he’s got over them, he’s more than welcome to enter a ring with me. It’s something that we should be focusing on in 2018.

“With all due respect to Tyson Fury, I think it would be wise if his handlers got him a few fights, get the body ticking over again and then get that love for the sport back. A few wins under the belt and then we can get it cracking.”

Joshua also made it clear that he doesn't respect Fury - because of all the trash talking done by the Gypsy fighter in the last two years.

"What we are achieving as heavyweight champions is phenomenal," Joshua told BBC


ox 78%." " B.P. 68 over 34." " What is the matter with him?" "Would you come with me?" "There are procedures we need to go over." " What kind of procedures?" " We're admitting your son." " You need to fill out the proper forms." " What kind of forms?" "Your son may need a transfusion." "We'll need to test you both for blood type." " We're coming right back, baby." " Wait a minute!" " First name, Mr Archibald." " John." " Middle initial?" " Q. Quincy." "Name of your insurance company?" " Where is he?" "Is he okay?" " We don't know." "They're running tests." " We're waiting to find the results." " Is there anything we can do?" " Your card, Mr Archibald." "to here today." " Not at all." " What can I do you for?" "My son Mike, he fell into heart failure at this Little League game." "I got full insurance from the job." "Now they're telling me they won't pay." "What about the hospital?" "Don't they have to cover it?" " That's what I was saying." " They're telling me I got to pay cash." "Otherwise I got to take my son home and watch him die." "We was thinking you can do one of them special interest pieces." "Send donations, write your congressman." "Anything you can do, Mr Lampley, would help." "I think what's happening to your son is outrageous." "I want to help." "I got to run this by my producers." "I got bosses like


Archibald." " You, too." "Take care of his ear." "The gunman has just freed several hostages." "who will immediately be debriefed by members of the crisis team." "Will the man known as John Q get a heant for his little boy?" "Only time will tell." "From Hope Memorial Hospital." "I'm Tuck Lampley." "Is it true an ambulance dropped off a victim after the gunman took over?" "He unlocked the door and he let him inside!" " Can you comment?" " The man was critically injured." "If he hadn't let him in, he would have died." " Ma'am, are you all right?" " I feel good." "We're having a baby!" "Ma'am, any comments about the gunman?" " John Q very good man." " The gunman?" "Very good man!" "Theya call between this guy and his wife." "Are you with the wife?" "All right, let's patch it through." "This better be good, Frank." "God, baby." " We're on the list." " What?" "Payne just left here." "Mikey's name is on the list." " Baby, you did it." " What?" "We're on the list?" "This is great, baby." " We got sound." " Where's the video?" "I need picture." "Boss, hang on." "I'm going to make you really famous." "I'm just..." "That's great, baby." "How's Mikey doing?" "Not too good." "I think he's going away." "What?" "They've done everything they can for him, but he keeps getting worse and worse." "Oh, God." "Our poor baby." "Are you praying for him, John?" "Are you praying for our baby?" "Yes,


you were going to call me back, but you didn't." "I gave you your hostages, but you didn't call me back." "Why?" " Because you want me dead." " Nobody wants to kill you." "Nobody wants to kill me?" "None of these guys?" "Not him?" "What is this?" "What did you think would happen?" "You want truth?" "Here's some truth." "This is going to end up bad for you." "There's only two ways out of here." "Jail or dead." "My son is very sick and he needs some help." "It's hard to be a man these days, hard to know what the right thing is." " But put the gun down, John." " You're not hearing me, Frank!" "My son is sick!" "That's it!" "There's nothing else." "Enddead, why not?" "You are the finest surgeon I have ever known." "You cannot throw your career, your life away for this." " If you do this, you're finished." " What are they going to do, sue me?" "Disbar me?" "Evict me from the country club?" "This is still a hospital." "If there's a heart available, I'm not going to let it go to waste." "Doctor, Mr Maguire, let's get ready for surgery." " They're ready to harvest." " All right, hurry up, guys." "Get her on the table." " What's our time?" " All right, ready to lift." " Count of three." " Oh-four-five." " Scalpels laid out." " Where's his tray?" "Got the other one ready?" "Bring the cart around, please." "What do we have?" "Female


on Twitter, for example.”

While Portable.TV doesn’t disclose any overt ties to RT, the links between the two are easy to discern. All of the social media links on Portable.TV’s site—to its Instagram, Facebook, and Twitter accounts—redirect to RT America’s social media accounts. And one of the videos on Portable.TV’s actual Facebook page has a number of RT hosts plugging the app—with one weirdly claiming that “Stars will talk to you!”

What’s more, the copyright listed for the Portable.TV app is listed as T&R Productions, LLC, which Portable.TV also lists on its site as its parent company. T&R Productions, LLC happens to be the same corporation that registered in 2017 as an agent working on behalf of ANO TV-Novosti, the Russian governmental entity that oversees worldwide broadcasts of RT. PerPortable.TV app. RT did not respond to The Daily Beast’s questions about the app, nor about why Portable.TV doesn’t disclose any relationship with RT.

“Sounds like they’re upset about the increased transparency that users now have around who produces their content, or upset about the fact that social platforms are rethinking the weightings that kept their algorithms serving up state propaganda,” DiResta told The Daily Beast. “The Apple Store does not do anything to indicate the provenance of this app… While several social platforms have made FARA disclosures far clearer so that their users are better informed about what they are engaging with—Facebook and YouTube both indicate that RT is an agent of the Russian government—the App Store doesn’t appear to.”

It’s unclear why those behind Portable.TV felt the need


V6 specific mAb 2B12, CD44 standard form binding mAb 2G10, and CD44 link domain specific mAb F2-1A6.](pone.0111339.g005){#pone-0111339-g005}

![Breast tumor tissue array staining by immunohistochemistry with CD44 mAbs.\
A tissue array containing samples from 8 different patients (numbered 1--8) was evaluated after staining with different CD44 mAbs. A) V7 specific mAb 2A6, B) V6 specific mAb 2B12, C) CD44 standard from binding mAb 2G10, D) an enlarged view of tissue \#3 stained with 2B12 showing distinct membrane bound CD44v6 in the center of a subset of cancerous cells. Magnification is 400x, and the scale bar is 50 µm.](pone.0111339.g006){#pone-0111339-g006}

Breast tumor sections stained with three antibodies, 2A6, 2B12, and 2G10, also demonstrated unique CD44 staining patterns. The V7 and H specific Abs showed diffusing staining with epithelial cells including the normal mammary duct,the V6 specific 2B12 antibody stained a subset of the tumor epithelial cells with a distinctive membrane pattern ([Figure 6](#pone-0111339-g006){ref-type="fig"}). The biological relevance of V6 within the tumor tissue is unknown.

Other cell binding antibodies were also validated for cell staining and internalization. Ab internalization was evaluated using the chelated ligand-mediated internalization assay (CLIA). Specifically, the histidine-tagged scFv coupled with the Ni-NTA coated fluorescent liposome bound the target receptor on the intact mammalian cell surface at 4°C compared to that internalized into the cells at 37°C. The surface bound liposomes were removed by imidazole wash showing no fluorescence signal left for the 4°C incubation group, while the internalized liposomes remained for the 37°C incubation group ([Figure 7](#pone-0111339-g007){ref-type="fig"}). The ratio of fluorescence between the imidazole and the PBS wash reflected


cells.](pone.0111339.g007){#pone-0111339-g007}

Breast cancer cell lines known to express the target antigens ErbB2, EphA2, EphB3, and CD44 with high and low levels were stained with the identified phage mAbs and evaluated by fluorescence microscopy. Consistent with the gene expression data [@pone.0111339-Spellman1], EphB3 antibodies stained MDA-MB-453 cells, CD44 and EphA2 antibodies were positive on MDA-MB-231, and the ErbB2 domain 1 binders showed intensive intracellular staining of ErbB2 positive AU565 cells ([Figure 8](#pone-0111339-g008){ref-type="fig"}).

![Binding of mAbs to cancer cell lines that overexpress the target antigens as determined by fluorescent microscopy.\
A) EphB3 mAbs showed positive staining on EphB3 overexpressing cell MDA-MB-453, B) CD44 and EphA2 mAbs showed positive staining on MDA-MB-231 cells, C) ErbB2 domain 1 binding mAbs showed positive staining on the ErbB2 overexpressing cell AU565.](pone.0111339.g008){#pone-0111339-g008}

Discussion {#s3}
==========

We have demonstrated that antigen yeast displayhr at 4°C. The filtered supernatant containing the depleted phage library was then aliquoted into each well of 1 ml 96-well plate containing about 1×10^7^ yeast cells displaying individual target protein domains for 1 h at 4°C. Yeast cells were washed ten times with cold PBS and pelleted by centrifugation. The bound phage antibodies were eluted by incubating yeast cells with 100 µl of 100 mM triethylamine, neutralized with 50 µl of 1 M Tris-HCl (pH 7.4), and used to infect exponentially growing *E. coli* TG1 as described previously [@pone.0111339-Marks1]. Specifically, half of the phage eluent was transferred to a new 1 ml 96-well plate, incubated with 1 ml of *E. coli* TG1 cells for 30 min at 37°C, and 1/10 of the infected TG1 transferred to a


why it should receive attention.

Deciding whether to fix the problems
With such a large code base, you cannot solve everything; your bosses are likely to get nervous if too much money is spent on an effort which they probably already think is going to be like throwing money into a pit.
Do a risk assessment for each area of code which you've identified as being problematic:

What happens if something in there breaks?
Which customers are affected?   How disruptive is it to them?
How much money is the company currently spending maintaining that area of code?
If the refactoring fails and causes more problems, what's the worst-case scenario?  e.g. does it make the whole system unusable for everybody or does it only affect a minorUpload your profile photo

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out that we need to look elsewhere to understand the reason for Nietzsche's position – since BGE 16 provides no clues here –, I do not think that GS 54 is the right place to look. In this aphorism Nietzsche writes: What is "appearance" to me now! Certainly not the opposite of some essence – what could I say about any essence except name the predicates of its appearance! Certainly not a dead mask that one could put on an unknown x and probably also take off x! (GS 54) 11 Maudemarie Clark, Nietzsche on Truth and Philosophy, Cambridge 1990, p. 90. 7 Commenting on these lines, Clark argues that Nietzsche "denies that we have any way of conceiving of such an essence", since we have no wayin addition to the relational properties such objects exhibit in experience, they must be thought of as having intrinsic properties, the more so as we are constitutively unable to determine which properties they might have. Theoretically speaking, do relational features not suffice? Moses Mendelssohn puts this exact question to Kant, who answers in a short work from 1786, entitled Einige Bemerkungen zu L. H. Jakob's Prüfung der Mendelssohn'schen Morgenstunden. I feel that this brief exchange throws some interesting light on this topic, and I would therefore like to examine the more controversial aspects more closely. Mendelssohn's argument is as follows: If I tell you how a thing effects or suffers, do not continue to ask what it is! If I tell you how to conceive of a thing


R. Hill, Nietzsche's Critiques. The Kantian Foundation of His Thought, Oxford 2003, p. 139. I thank Tsarina Doyle for pressing me on this point. 29 See Avenarius, Philosophie als Denken der Welt, p. 64, § 112. 17 In conclusion, it is now possible to differentiate between two different degrees in Nietzsche's critique regarding the notion of thing in itself. Firstly, according to him, Kant's postulation of an intrinsic and subject-like substratum as the necessary complement to relational properties is unsubstantiated. Secondly, the concept of "thing in itself" is not only deduced on the unfounded assumption that something defined only by external relations must have the second-rank ontological status of "appearance", but also turns out to be identical to the self-contradictory notion of a propertyless thing. Nietzsche contrasts thisQ:

How to update a String with an Array in a document within Robo3T?

I am trying to change an element object that is within an array in a document on Robo3T.
The structure looks like this:
  {
    "_id" : ObjectId("1234"),
    "source" : "BW",
    "sourceTableName" : "lwtrmls",
    "tableName" : "tier",
    "type" : "main",
    "primaryKeys" : [
        {
            "sourceField" : "tier_id", // <~~~~ This is what I am trying to update!
            "reportingField" : "bw_id",


problems before they can be exploited by virus producers. In fact, most of the time the application manufacturers have released the fixes to the application that would have prevented a virus from utilizing these holes before the viruses are even released. Unfortunately, due to the complexity of modern networks, most system administrators are unable to keep pace with the increasing number of security patches and hot fixes released from the software manufacturers on every computer in the network.
What is needed is a solution that automates the process of identifying and managing network application security holes. Typical solutions to this problem involve the user of multiple applications installed one various computers. These applications are executed when certain conditions occur. For example, a company may install several anti-virus components that
 */
public class UpdateByExampleSelectiveMethodGenerator extends
        AbstractJavaMapperMethodGenerator {

    @Override
    public void addInterfaceElements(Interface interfaze) {
        Set<FullyQualifiedJavaType> importedTypes = new TreeSet<FullyQualifiedJavaType>();
        Method method = new Method();
        method.setVisibility(JavaVisibility.PUBLIC);
        method.setReturnType(FullyQualifiedJavaType.getIntInstance());
        method.setName(introspectedTable
                .getUpdateByExampleSelectiveStatementId());

        FullyQualifiedJavaType parameterType =
            introspectedTable.getRules().calculateAllFieldsClass();
        method.addParameter(new Parameter(parameterType,


comments could also be taken as another sign that he plans to reform church rules that prevent divorced Catholics from receiving the Eucharist.

“Everyone can share in some way in the life of the Church; everyone can be part of the community, nor should the doors of the sacraments be closed for simply any reason,” Francis said.

“The Eucharist, although it is the fullness of sacramental life, is not a prize for the perfect but a powerful medicine and nourishment for the weak.”

Even so, Francis reiterated the church’s stand against abortion, defending it against critics who call such arguments “ideological, obscurantist and conservative.”

“Precisely because this involves the internal consistency of our message about the value of the human person, the Church cannot be expected to change her position on thisof the vacuum on carpets and stairs are the most wonderful things to mention. Due to the long cord and the canister which can access to dark areas with the LED headlights. Furthermore, this dust containment system helps keep dust and allergy-causing agents from escaping back into the air by combining with the filters.

Otherwise, you may find this vacuum does not come as you expect. For instance, you may consider its price is not worth with what it provides. Also, the suction is subpar and the main brush head is too small so it takes you much longer time to clean the house.

My rating

Herein, I would like to use 10 factors (as I mentioned above) and mark each of them from 1 to 10. Now this is the


Syringoceles of Cowper's ducts and glands in adult men.
Cowper's syringoceles are uncommon, usually described in children and most commonly limited to the ducts. We describe more complex variants in an adult population affecting with varying degrees of severity, the glands themselves, and the complications they may lead to. One hundred consecutive urethrograms of patients with unreconstructed strictures were reviewed. Twenty-six patients (mean age: 41.1 years) with Cowper's syringoceles who were managed between 2009 and 2016 were subsequently evaluated. Presentation, radiological appearance, treatment (when indicated), and outcomes were assessed. Of 100 urethrograms in patients with strictures, 33.0% demonstrated filling of Cowper's ducts or glands, occurring predominantly in patients with bulbar strictures. Only 1 of 26 patients with non-bulbar strictures had a visible duct/gland. Of 26 symptomatic patients, 15 presentedClause of the Fifth Amendment or Article I, § 14 of the Indiana Constitution to charge and convict a person for both a substantive offense and a conspiracy to commit the substantive offense.
Id.;[1]citing e.g. Derado v. State, 622 N.E.2d 181, 184 (Ind.1993), Witte v. State, 550 N.E.2d 68, 71 (Ind.1990), Hammers v. State, 502 N.E.2d 1339, 1343 (Ind.1987). Ultimately, in Derado and Buie, the court found double jeopardy violations in the sentencing for conspiracy and the substantive offense. In both cases, the court found no Blockburger violation, but instead found that the charging information relied upon the substantive offense to prove the overt act in furtherance of the conspiracy. After Games and Grinstead, it is clear that courts will not engage in double jeopardy review which extends beyond


correctly synchronized.
Avoid surprises if a type locks on itself
Usable even when re-assigning the HashSet member

However, because a separate lock object doesn't lock on the HashSet, if something else expects that it does ..

1 The new lock object creation cost is ignorable. The CLR enters a monitor in the same manner for both cases described.

partial monosomy of 18q. Snapshots of microarray plots and coding genes in sequential order of dup 12p13.33p13.32 and del 18q22.3q23 are shown in Figures [3(c)](#fig3){ref-type="fig"} and [3(d)](#fig3){ref-type="fig"}. Parental evaluation was normal.

[Table 1](#tab1){ref-type="table"} gives the molecular karyotype of these children with base pair location, size, number of genes involved, and the critical regions for phenotype correlation.

4. Discussion {#sec4}
=============

ES (Proband 1) is the prototype of complex and small supernumerary marker disorders. The most common non-Robertsonian rearrangement in humans is the translocation between chromosomes 11 and 22 as these chromosomes have palindromic AT repeats that are vulnerable to breaks and recombination during meiosis. ES results from 3:1 mal-segregation of usually the maternal balanced carrier state as in our case \[[@B9], [@B10]\]. The incidence of ES is not known. Features typical of


should consider targeting other proteases (e.g. cathepsin D, cathepsin L, or other metalloproteases). The automated assays we will use for this retrospective screening of tumor tissue banks may later serve as diagnostic assays to direct inclusion of class-specific inhibitors as adjuvant therapy in individual patients. The Biochemistry Core will also screen tumor cell lines developed and used by the Cell Biology and confirm protease or inhibitor expression for the Transgenic Core (Core C). By comparison to the relevant human cancer tissue bank, the cell lines which best reflect protease expression in actual tumor samples can be identified. Proteases (and, if relevant, protein inhibitors) will be localized by immunohistochemistry or active site-directed biotinylated probes. If any variants of known proteases are identified as having altered substrate specificity or localization,Anambra worst hit by flood – Presidential team

•Gov. Obi (Middle), conducting the Minister of Aviation, Princess Stella Oduah (left) and the Minister of Environment, Hadiza Ibrahim Mailafia (right) during the tour of flooded local government areas in Anambra State in a helicopter.

A presidential delegation led by the Minister of Environment, Hadiza Ibrahim Mailafa, visited Anambra State on Thursday and declared it the worst hit by the floods that have ravaged 14 states in the country lately.

Accompanied by the the Minister of Aviation, Princess Stella Oduah; the Minister of State for Works, Ambassador Bashir Yuguda; and theDirector of the National Emergency Management Agency, Mohammad Sani Sidi, Mailafia observed that the state is located at the lowest point of the River Niger and that must have occasioned the enormous destruction


Deal alert / Lisa Stansfield: The Collection 1989-2003 box set

Incredible price for the 18-disc Lisa StansfieldThe Collection box set today on Amazon UK…
If you need reminding, this set includes of all Lisa’s Arista albums – Affection (1989), Real Love (1991), So Natural (1993), Lisa Stansfield(1997) and Face Up (2001) – as 2CD+DVD casebound book deluxe editions, as well as a remix compilation called People Hold On… TheRemix Anthology – a three-CD set that containsover thirty rare and previously unheard full-length mixes.

The price for this box right now is just £40 and it looks as if Amazon (many Amazons!) are price-matching a third party seller. My guess is that the third party seller won’t have too much stock and once they sell out the ‘Sold by Amazon’ price will---
abstract: 'Assume that $X$ is a smooth projective 3-fold with ample $K_X$. We study a problem of Miles Reid to prove the inequality $$K_X^3\ge \frac{2}{3}(2p_g(X)-5),$$ where $p_g(X)$ is the geometric genus. This inequality is sharp according to known examples of M. Kobayashi. We also birationally classify arbitrary minimal 3-folds of general type with small slope.'
address: 'Institute of Mathematics, Fudan University, Shanghai, 200433, PR China'
author:
- Meng Chen
title: Minimal threefolds of small slope and the Noether inequality for canonically polarized threefolds
---

**Introduction**
================

We work over an algebraically closed field $k$ of characteristic 0.

On an irreducible complete curve $C$ (may be singular), one has $\deg(K_C)\ge 2g(C)-2$ where $g(C)$ is the geometric genus of $C$.

This inequality has a 2-dimensional analogue which is the famous “Noether’s inequality” (see [@N]). Explicitly, on a minimal surface $S$


may see that $\pi_B$ is an embedded resolution of $(X,Z)$.

[**The inequalities for Type A) case.**]{} We apply the argument in \[main\]. We take two integers $m$ and $n$ such that $1-\frac{na_1}{ma_1+s}>\frac{1}{10}.$ Write $a:=a_1m+s$ as in \[main\]. In order to get an effective inequality, we only need to verify the condition (\*). For simplicity, we still denote $\pi_A$ by $\pi$. Recall that we have $$\pi^*(K_X)|_S=\pi^*(Z)|_S=10L_4+5L_3+4L_2+2L_1+\tilde{C}$$ where $L_4^2=-1$ and all these curves are smooth rational curves. Set $D_0:=(\pi^*(Z)|_S)_{red}$. Then $D_0$ is of course a rational tree. From the intersection form of $\pi^*(Z)|_S$, we have $$D_0\cdot L_4=2.$$ Now we verify the condition (\*). For a general fiber $S$, we have $$\begin{aligned}
&h^0(S, K_S+{\ulcorner{(\pi^*(K_X)-\frac{na_1}{ma_1+s}\pi^*(Z))|_S}\urcorner})\\
\ge&h^0(S, K_S+D_0+L_4)=h^0(S, K_S+{\ulcorner{\frac{1}{5}\pi^*(Z)|_S}\urcorner})\\
=&\frac{1}{2}(K_S+D_0+L_4)(D_0+L_4)+\chi({\mathcal O}_S)=3.\\\end{aligned}$$

Thus the inequality (\[key\]) gives $$\label{TA}
K_X^3\ge 2(-2p_g(X)+\delta+(2+\frac{n}{m})a+3h^2({\mathcal
O}_X)-3b-\frac{n(m-1)}{m}+1).$$

Now we see that, if $p_g(X)$ is very big (thus $m$Q:

Composite and Observer pattern implementation

I'm learning Composite and Observer design patterns and I have created a FileSystem class where I define Node, Folder and File as a composite relationship. Now I want to implement Observer pattern so when there is a FileBrowser/Finder/File Explorer Observers they can get updated when I add a File to a Folder.
This is my relationship and code:

Im implementing the Subject Interface for Node (Component) and in Directory itself I implemented the Subject methods: attach, dettach and notifyObservers.
Is this a good design? What If I want to get notifications for folder and subfolders? do I need to pass each Directory to my FileBrowser observer?
If a File change we may need to duplicate the code meaning add attach, dettach and notifyObservers to my File class?.
public class


At 88-years of age, Clint Eastwood has another major box office success on his hands. As of this weekend, The Mule, which Eastwood both stars in and directs, has cleared an incredible $81 million.

Outside of Eastwood’s unprecedented staying power as a major star, director, and composer, what makes this success so surprising is that his little movie was released without much fanfare or advanced publicity. Many believe this was due to the studio’s fears about some of the movie’s content.

The Mule (you can read my review here) is based on the true story of 90-year-old Leo Sharp, who worked for a decade as a drug mule for a Mexican drug cartel. Eastwood does not shy away from presenting people, including his own character, as they really are, andthe United States House Committee on Agriculture, which considered, marked-up, and reported the bill on May 15.   The vote was 36-10.  It was also referred sequentially to the United States House Committee on the Judiciary (voice vote - June 6) and to the United States House Committee on Foreign Affairs (discharged June 10).  The bill was placed on the Union Calendar, Calendar No. 73. on June 10.  The House started considering the bill on the floor during the week of June 17, 2013.

On June 20, 2013, the Federal Agriculture Reform and Risk Management Act of 2013 was received a vote on the House floor - it failed 195-234 (Roll Call 286).  Only 24 Democrats voted in favor of the bill, with most


Multifactor Authentication (MFA) Device in the IAM User Guide.

When working with a policy like the one we just created, we recommend restricting users’ access to just the console. Thus, when you create these users with delete privileges, you only grant them “AWS Management Console access”.

Summary

This blog post shows you how to set up IAM security policies that provide the flexibility to innovate within your account while at the same time providing a mechanism to protect critical data resources. Also, we showed how to use MFA to provide an extra layer of security for destructive actions. Now you have a method to restrict destructive requests to only specified individuals with a means to control access.

About the Author

Phil Intihar is a database engineer at Amazon Web Services.Korean Pop, known universally as K-Pop, has been around since the 1990s. In 2012, a K-Pop artist known as PSY broke the internet with his hit “Gangnam Style,” garnering around 1.7 billion views on YouTube.

For many, PSY may be considered a trailblazer for K-Pop music, but he is unable to say he beat Justin Bieber, Selena Gomez, Ariana Grande and Shawn Mendes for the Top Social Artist award at the 2017 Billboard Music Awards. Actually, another K-Pop group did. A boy band called BTS took the award home, to the shock of many.

BTS, also known as the Bangtan Boys or Bulletproof Boy Scouts, is a seven-member South Korean boy band formed by Big Hit Entertainment. Their members include Jin, Suga, J-Hope, Rap Monster, Jimin, V and Jungkook. The


ages of the group at the time of their debut, in 2013, ranged from 16 to 26.

They debuted with the song “No More Dream” from their first album called “2 Cool 4 Skool.” As BTS isn’t under the umbrella of the three major companies in South Korea (SM Entertainment, YG Entertainment or JYP Entertainment), it was unimaginable that BTS would become as popular as they did.

You might also like: The BTS Fan Base’s Love-Hate Relationship With Streaming Services

Within the majority of K-Pop groups, each member has a position or role that they are assigned or take on. Rap Monster, whose real name is Kim Nam Joon, is the group’s leader and main rapper. Outside of management, he’s responsible for the group and songs.

The oldest member, Jin, whose fullthe name is that “army” is military in English, and body armor and military are always together, meaning that the fans will always be with the Bangtan Boys. With their loyal ARMY, BTS’ singles and mini albums rose above the rest, and they continued to gain more and more momentum with each passing year.

However, it was the septet’s second full-length album, “Wings,” that caused American music awards to take notice. Released in October 2016, “Wings” contains fifteen tracks. The album touched on the theme of mental health, poked at the K-Pop “idol” scene and delivered a female-empowerment anthem, which are all considered unusual, as the norm for K-Pop music is talking about break-ups and partying.

The most noticeable song on the album is the Moombahton trap single “Blood Sweat


specialists (originally, the consultants who built Chef itself) configure Linux-based servers and components.

If that sounds like six of one, half a dozen of the other, that's because ultimately, Puppet and Chef are different approaches to the same, Linux configuration problem,
and ultimately achieve the same results:

In Puppet, you write a manifest file using PuppetScript that declares a desired state of configuration.

In Chef, you write a recipe using Ruby that describes the steps required to configure a server.

We mention all this because the reasons that people choose Puppet over Chef, or choose Chef over Puppet have been documented for years, and these were key considerations when we designed Otter.

Chef requires a proficiency in Ruby to do anything but trivial configuration tasks

Chef's architecture and components are much more complex to understandis built in to Otter. Servers can be configured to automatically remediate drift or simply report on it and give you the option to schedule a job to automatically remediate the drift. These are all first class concepts, as opposed to afterthoughts.

Chef's Ruby Libraries vs Otter Plans

Ruby is a general-purpose programming language, which makes it difficult to compare and contrast to OtterScript, which is a language designed specifically for the purpose of configuration management and infrastructure automation.

There's no question that a general-purpose programming language offers near-infinite flexibility, and that's precisely why Otter has such
tight PowerShell/scripting integration: when the high-level execution engine isn't the right tool for the job, just PSExec what you need.

Simplicity aside, OtterScript does have distinct advantages over Ruby, and most other general-purpose programming languages. Of


Maria as sole managing conservator of T.H.A.G. Even though

       2
           Hugo has three other children he visits, one in Mexico and two in Canada.

                                                     2
the order was rendered by default, Hugo was named possessory conservator, albeit

without visitation rights.

       In April 2011, Hugo filed a petition to modify the 2010 order alleging a material

and substantialsister also filed suit to terminate Hugo’s parental

rights to his older son, T.H.A.G.’s half-brother. The cases were consolidated and tried

to the bench. The trial court terminated Hugo’s parental rights to his older son but found

it was not in T.H.A.G.’s best interest to terminate the parent-child relationship. Hugo

was granted supervised visitation with T.H.A.G. and was ordered to pay monthly child

support in the sum of $184 per month. The order also modified Maria’s exclusive right

to designate her son’s primary residence by limiting it to Wilbarger County, Texas. The

trial court filed Findings of Fact and Conclusions of Law. Conclusion of Law 16 provides

“[i]t is not in the best interest of the child to terminate the parental rights of [Hugo] to

[T.H.A.G.].” Conclusion of Law 19 provides “[i]t is in the best interest


child was honest. She opined it was in his best

interest to terminate the parent-child relationship.

       On the other hand, the counselor had only two visits with T.H.A.G. when he was

four years old. She described him as a “sweet little boy who was silent.” She found his

lack of communication disturbing, and her opinion regarding any contact between him

and his father was the same as for the older brother. However, when questioned by the

court on whether the same situation existed as with the older brother, she testified

“there’s no way for me to know other than the fact that they are brothers.”

       At the time of the hearing, Maria and T.H.A.G. were living with her sister and her

sister’s husband      We review a trial court’s modification order in a family law case for abuse of

discretion. In re M.S.F. and M.S.F., 383 S.W.3d 712, 715 (Tex. App.—Amarillo 2012,

no pet.). Absent a clear abuse of discretion, the trial court’s order modifying the prior

order will not be disturbed on appeal. Id. A trial court abuses its discretion when it acts

arbitrarily or unreasonably or when it clearly fails to correctly analyze or apply the law.

In re D.S., 76 S.W.3d 512, 516 (Tex. App.—Houston [14th Dist.] 2002, no pet.).

           Section 156.101 of the Family Code provides for modification of an order for,

among other things, possession of or access to a child if modification would be in the

child’s


1996, no writ).

       During the hearing, Maria moved for directed verdict on the modification issue

arguing that none of the grounds in section 156.101(a) of the Family Code had been

established to justify modification of the prior order. The motion was overruled. Here,

Maria relies on an interrogatory in which Hugo was asked to identify the material and

substantial change in circumstances to which he replied “of no consequence except for

[Hugo] will clarify.” She also asserts Hugo failed to prove a material and substantial

change during his case-in-chief.

                                       and course descriptions at the top of the page.

Tuition discount

Students are eligible for Point Park’s tuition discount being offered for all certificate and master's degree education programs. This tuition discount is approximately 47 percent below the standard rate for master's degree programs and 41 percent below the standard rate for certificate programs.

New and returning education certificate and master's degree students will receive this lower tuition rate as follows:


trials showed effectiveness of high-dose ifosfamide alone \[[@CR23]\], a combination of gemcitabine and docetaxel \[[@CR24]\], pazopanib \[[@CR25]\], and elibulin \[[@CR26]\]. Trabectedin, a marine-derived antineoplastic drug and multitarget agent, which induces apoptosis and cell cycle arrest, is especially effective for translocation-related sarcoma, including SS \[[@CR27], [@CR28]\]. Phase 1 studies of the new potential therapies related to genetically engineered T lymphocytes and immunotherapeutic vaccines are ongoing.

Conclusions {#Sec4}
===========

Monophasic SS, an extremely rare tumor in the esophagus, is difficult to distinguish from other spindle cell tumors. When an esophageal spindle cell tumor, especially of the polypoid type and located at the cervical to upper third of the thoracic esophagus, is observed, the possibility of SS should be considered. Molecular analysis appears useful for confirming the diagnosis of monophasic SS.

SS

:   SynovialQ:

TIdHTTP in Indy 10

I used to use Indy back in the Delphi 6 days, and I am playing with Indy 10 now.  What I want to do is incredibly simple, but I don't see a simple way of doing it, so I must be missing something.
What I want to do is something like this:
Here is the actual code I am using:
procedure TForm1.btnGetURLClick(Sender: TObject);
begin
  moHeader.Lines.Clear;
  moBody.Lines.Clear;
  try
    moBody.text := IdHttp1.Get(edURL.text);
  finally
  end;
end;

When the request is complete, the http_result should contain the HTML from the URL specified.  This doesn't seem to work however, so I get the feeling I should perhaps be using the IOHandler property or the OnWork event of the component - however the usage


optimize the wrapper away. Since it is a standard solution, many libraries handle it out of the box. The disadvantage it that the optimization doesn’t work reliably, so e.g. mocking is almost completely broken (because sometimes the value is boxed and sometimes wrapper is optimized away).

As a some sort of middle-ground a newtype library was designed.

@newtype case class Name ( value : String )

It lets you declare your new type as a case class (which helps with IDE support), while macro annotation rewrites it into:

type Name = Name . Type object Name { type Repr = String type Base = Any { type Name$newtype } trait Tag extends Any type Type <: Base with Tag def apply ( x : String ) : Name = x . asInstanceOfAleppo bombing 'kills 14 members of one family' Published duration 17 October 2016 Related Topics Syrian civil war

image copyright AFP image caption Rescuers used a crane to reach this 12-year-old boy who was trapped in rubble

Fourteen members of one family have died in an air strike on rebel-held east Aleppo, volunteer rescuers say.

Eight children and two women were among the dead, said the civil defence force known as the White Helmets.

An Aleppo resident told the BBC the city had endured heavy bombing in the past 24 hours, with "bunker-buster" munitions shaking the ground.

The EU foreign affairs chief has said sanctions against Syria might be expanded.

But Federica Mogherini said increased sanctions against Syrian President Bashar Assad's Russian backers were not on the agenda.

She was speaking as EU foreign ministers


Frequency and phase controllers, such as disciplined oscillators as described in the above-referenced U.S. patent and also the Stratum 2 disciplined oscillator sold by Spectracom Corporation, East Rochester, New York 14445 U.S., have used digital techniques for locking a standard oscillator to a reference and even removing long term phase and frequency variations to high degrees of precision. In such systems the reference frequency source is reliable (essentially uncorrupted by noise and other errors) for long periods of time, or the reference frequency source is located close by the controlled standard source and provides continuous, essentially noise and error free reference signals. The reference signals are also available at high frequencies, for example 10 Mhz so that frequency and phase errors are detected quickly while the reference isConsistency between causality assessments obtained with two scales and their agreement with clinical judgments in hepatotoxicity.
Reliability and usefulness of scales for causality assessment in hepatotoxicity have not been fully explored. The goal of this study was to examine consistency between causality assessments obtained with two commonly used scales and their agreement with initial clinical assessments in hepatotoxicity reported in Serbia, and to review usefulness of these scales. We compared the two scales (CIOMS/RUCAM and NARANJO) in 80 cases reported during 1995-2009. The initial clinical assessments performed at the time of reporting served as a control for comparison with the subsequent causality assessments. The agreement between obtained causality assessments and the initial clinical assessments were analysed by Kappa weighted (K(w)) statistical test. In the 80 cases, the NARANJO scale


of waves, the rate of change of the velocity, and the duration of the event. Shear waves, or S-waves, are the primary signal generated by an earthquake. When an extreme disturbance occurs in an homogeneous environment, a spherical front is generated, and a P-wave results. Such a wave is characterized by alternating compression and rarefaction through the sub-surface of the earth, somewhat similar to the structure of sound waves in air. Nuclear blasts in conjunction with underground tests primarily radiate P-waves.
At the interface of the earth with air Rayleigh waves are generated. Such waves are associated with both earthquakes and underground nuclear tests. Love waves are generated primarily from earthquakes, and are generally transverse to the direction of travel of Rayleigh waves. A variety of other complex waveformsrange ([Figure 1B](#F1){ref-type="fig"}, blue shade).

We next applied this assay to community testing and obtained serum samples from 5882 self-recruited volunteers from Pima County. Donors included healthcare workers (\~26%), first responders (\~27%), University of Arizona students (\~5%), and other members of the general public (\~42%). Currently febrile or otherwise symptomatic patients were excluded. Sera from 73 individuals preliminarily scored as seropositive ([Figure 1D](#F1){ref-type="fig"}). These samples, along with another 171 samples with OD~450~ values in the indeterminate range were tested for virus neutralization at a serum dilution of 1:20 ([Figure 1E](#F1){ref-type="fig"}). Nine samples with RBD OD~450~ values below 0.39 were observed to neutralize SARS-CoV-2 ([Figure 1E](#F1){ref-type="fig"}). More problematically, we found that 13 of the 73 samples (17.8%) called positive by RBD-reactivity failed to neutralize authentic SARS-CoV-2 ([Figure 1E](#F1){ref-type="fig"}). If virus


serum samples from healthy controls and COVID-19 cases. (**D**) Pre-pandemic negative control samples (272) were screened for seroreactivity against S2 and compared to 30 PCR-confirmed SARS-CoV-2-exposed sera. (**E**) Comparison of RBD and S2 seroreactivity across 272 pre-pandemic serum samples. (**F**) ELISA results from indeterminate and putative seropositive samples from community testing. Thresholds for seropositivity were defined as in (**E**). Red circles indicate samples that have PRNT~90~ titers of at least 1:20. Experiments were repeated at least once.](nihpp-2020.08.14.20174490-f0002){#F2}

![Antibody responses to SARS-Cov2 as a function of disease severity and age.\
**(A-C)** Antibody titers to RBD (A), S2 (B), and N (C), over time post-onset of SARS-CoV-2 infection symptom grouped by case severity. The negative control average was determined by calculating the average AUC value of negative control (n=25) samples. P valuesrepresent comparison of fit in nonlinear regression model between displayed groups. **(D)** PRNT~90~ values over time post-onset of SARS-CoV-2 infection symptoms. P values were calculated as in (A). **(E-H)** Antibody titers over time post-onset of SARS-CoV-2 infection symptoms from PCR+ confirmed patients or seropositive individuals from community wide cohort for RBD (E), N (F), and S2 (G), grouped by patient age. **(H)** PRNT~90~ values over time post-onset of SARS-CoV-2 infection symptoms grouped by patient age.](nihpp-2020.08.14.20174490-f0003){#F3}

![Antibody Responses to Spike Glycoprotein are more stable than responses to Nucleocapsid:\
**(A-C)** Antibody titers for mild infections over time to RBD (A), S2 (B), and N (C) for PCR-confirmed subjects and seropositive samples from community serological testing. Solid lines connect data from individuals sampled serially over time. Blue line depicts smoothing splines curve fit


Nightflyers (film)

Nightflyers is a 1987 American science fiction horror film based on Nightflyers, a 1980 novella by George R. R. Martin.

Plot
The film is about a group of scientists who begin a space voyage to find a mysterious alien being, and in the process are victimized by the ship's malevolent computer.

Cast
 Catherine Mary Stewart as Miranda Dorlac
 Michael Praed as Royd Eris
 John Standing as Michael D'Brannin
 Lisa Blount as Audrey
 Glenn Withrow as Keelor
 James Avery as Darryl
 Annabel Brooks as Eliza
 Michael Des Barres as Jon Winderman

Production

Development
The film is based on a novella that appears in George R. R. Martin's 1985 short story collection. Originally written in 1980, the 23,000-word novella was published by Analog Science Fiction and Fact. In 1981, at the request of his editorcharmed life, defined by exceptionalism, the justice system should have bowed to him and trundled off to hold less mortals accountable for their actions. Not the star athlete who overcame his disability to win gold medals for our country. Not the humanitarian who motivated others with disabilities to aspire to greater heights. Not the fragile victim of our crime-ridden society who became so paranoid that one of us might want to climb into his privileged sanctum that he was forced to shoot four bullets to kill someone.

No, not our Oscar. We simply cannot have him shut away when he could be helping the “less fortunate” among us.

This is what he told ITV in an in-depth interview in which he again indulged in his soppy, illogical version of what


the average scores of each ultrasound criterion of the healthy and diseased group. (b) Scatter plot illustrating the total ultrasound criterion of the healthy and diseased group. \*p\<0.05 compared to healthy group; \*\*p\<0.01 compared to healthy group.](Vetworld-12-1266-g001){#F1}

All animals were then divided into three different severity categories of total ultrasound score, namely, mild (score 0-2), moderate (score 3-5), and severe (score 6-12). The percentage of diseased dogs versus all animals in each category is shown in [Figure-2a](#F2){ref-type="fig"}. There were 17.4%, 88.2%, and 100% of dogs with liver diseases identified by mild, moderate, and severe ultrasound severity categories, respectively. More than 95% of healthy dogs had mild ultrasound score ([Figure-2b](#F2){ref-type="fig"}). Approximately 30% and 40% of patients with chronic hepatitis presented with mild and moderate changes in liver ultrasonographic features, respectively.and needs further evaluation.

ALT and ALP are among the most common liver enzymes abnormalities in patients with liver disease. Increased ALT and ALP serum activity indicates damage of the hepatocellular membrane and cholestasis, respectively \[[@ref2]\]. In this study, we demonstrated that dogs with moderate-severe ultrasonographic scores had a significant elevation of liver enzymes, ALT and ALP, compared to those of dogs with mild ultrasonographic scores. The relationship between ultrasound scores and ALT or ALP levels was positively correlated. Degree of hepatocellular damage and cholestasis indicated by elevation of ALT or ALP levels may lead to ultrasonographic changes in the liver. Our data may support the usefulness of ultrasound scoring system for the determination of the severity of liver damage and cholestasis. However, it has been shown that the


was not done for dogs in the healthy control group. Clinical data, biochemical data, as well as ultrasonographic features revealed no evidence of liver lesions in the control dogs. It should be noted that healthy dogs were younger than dogs with liver diseases. Young dogs have been shown to have a lower risk of developing liver disease than older dogs \[[@ref20],[@ref22]-[@ref24],[@ref28]\].

Conclusion {#sec1-5}
==========

Our semi-quantitative, simplified ultrasonographic scoring system assessing six different parameters may have potential to be used as a screening tool to detect some groups of liver diseases with structural changes including tumor and fibrosis, and a good diagnostic tool for evaluation of liver damage. Animals with severe ultrasound score category (total score 6-12) were also suggested for further diagnosis using liver biopsy. Beneficial role of our ultrasound1991 report from the region's bishops that concluded, "It cannot be affirmed that these matters concern supernatural apparitions or revelations."

In addition, he said, the commission would be asked to review pastoral provisions that forbid official diocesan and parish pilgrimages to Medjugorje, while at the same time allowing priests to accompany groups of Catholics in order to provide the sacraments and spiritual guidance.

When asked if the new commission was the idea of the doctrinal congregation or of the bishops' conference, Cardinal Puljic said, "I would rather not answer that question."

On 25 June, thousands of pilgrims converged on Medjugorje to mark the 25th anniversary of the first alleged apparition to six young people.

The Vatican continues to monitor events at Medjugorje, where the apparitions apparently continue, but it has not taken


cloves garlic, minced • 1 teaspoon minced fresh ginger

2 to 4 tablespoons berbere (Ethiopian chili powder)

1 cup water • 1 cup tomato sauce

About 1 teaspoon salt • About 1/8 teaspoon ground black pepper

1 (3- to 4-pound) chicken, cut into 12 pieces, or 6 chicken thighs and 6 drumsticks

4 to 6 hard-boiled eggs, peeled

1. In a dry large skillet or pot, cook the onions over medium heat, stirring constantly, until they begin to soften, about 5 minutes. Do not burn.

2. Add the oil. When it begins to sputter, add the garlic, ginger and berbere and sauté until fragrant, about 1 minute. Add ½ cup water. Add the tomato sauce, salt and pepper. Bring to a boil and cook, stirring constantly, until the liquid is reduced to the consistency of                          McCall, J., and Willson, J.)

      This court has inspected the record in this cause and concludes that there is
no error in the judgment below. Therefore, in accordance with this court’s
opinion, the judgment of the trial court is in all things affirmed.


app."""
    app.run(host='0.0.0.0')

@app.route('/')
def index():
    return "Hooray, you catch me !", 200

if __name__ == '__main__':
    manager.run()

when I run zappa deploy dev it returns 502 response error
ERROR showing :
Error: Warning! Status check on the deployed lambda failed. A GET request to '/' yielded a 502 response code.
here is zappa log :
[DEBUG] 2020-01-26T06:04:49.799Z 977e2eda-d28a-4d6d-9242-8d5e58423154 Zappa Event: {}
[1580018889972] Instancing..
[1580018889975] /var/task/bcrypt/_bcrypt.abi3.so: invalid ELF header: ImportError
Traceback (most recent call last):
  File "/var/task/handler.py", line 602, in lambda_handler
  return LambdaHandler.lambda_handler(event, context)
  File "/var/task/handler.py", line 245, in lambda_handler
  handler = cls()
  File "/var/task/handler.py", line 139, in __init__
  self.app_module = importlib.import_module(self.settings.APP_MODULE)
  File "/var/lang/lib/python3.6/importlib/__init__.py", line 126, in import_module
  return _bootstrap._gcd_import(name[level:], package, level)
  File "<frozen importlib._bootstrap>", line 994, in _gcd_import
  File "<frozenOracle 10g drivers are compatible with Oracle 9i.
The orai18n.jar file can be downloaded from the oracle site. Here are some
links:
http://www.oracle.com/technology/software/tech/java/sqlj_jdbc/index.html
Once on this page, click the "Oracle Database 10g Release 2 . . . drivers" link.
After accepting the license agreement, you will be brought to a page with a
list of drivers for download. Download the orai18n.jar file.
NOTE: You will need to sign in to Oracle to download the file. Registration is
free if you do not already have an id.
At this point, you can set up a JDBC connection to Oracle via RazorSQL that
references both the ojdbc14.jar file and the orai18n.jar file. This can be
done by going to the Connections - Add Connection Profile, selecting "Oracle" as the
database type, selecting "JDBC" as the connection type, entering the profile
name, the location


---
abstract: |
    Cofibrations are defined in the category of Frölicher spaces by weakening the analog of the classical definition to enable smooth homotopy extensions to be more easily constructed, using flattened unit intervals. We later relate smooth cofibrations to smooth neighborhood deformation retracts. The notion of smooth neighborhood deformation retract gives rise to an analogous result that a closed Frölicher subspace $A$ of the Frölicher space $X$ is a smooth neighborhood deformation retract of $X$ if and only if the inclusion $i: A\hookrightarrow
    X$ comes from a certain subclass of cofibrations. As an application we construct the right Puppe sequence.
author:
- |
    \
    [Cadiz Financial Strategists (Pty) Ltd, Cape Town, South Africa]{}\
    [Email: Brett.Dugmore@cadiz.co.za]{}\
show that $f\circ c_M:\mathbb{R}\rightarrow \mathbb{R}$ is smooth, it is obvious that we need only concentrate on the point $t=0$, because $f\circ c$ is smooth at every $t\neq 0$. It follows for $t\neq 0$, and $n\in \mathbb{N}$ that Lemma \[primary\] applies. But as $t\rightarrow 0$, $c_M(t)\rightarrow 0^+$, and so, letting $s=c_M(t)$, we have $$\lim_{t\rightarrow 0}f^{(j)}(c_M(t))=
\lim_{s\rightarrow 0^+}f^{(j)}(s)=0,$$for all $j\in \mathbb{N}$, by the zero derivative property of $f$. Thus, as $t$ approaches the value $0$, the primary term and all the lower order terms of $\frac{d^n}{dt^n}(f\circ c_M)(t)$ vanish, and we have shown that $f\circ c_M$ is smooth at $t=0$. This implies that $f\circ c_M\in
C^\infty(\mathbb{R}, \mathbb{R})$ for all $f\in F$. It follows that $c_M\in \Gamma F$.

We are now ready to show that $\mathcal{F}_\mathbb{I}\subseteq F$. To this end, suppose that we are given


since $H$ has the first coordinate independence property. For any $s$ in a neighborhood of $s_*$, $\alpha(\frac{\overline{u}(x(s))}{\overline{v}(y(s))})=0$. Thus, the component of $Q$ involving $J$ is constant for $s$ in a neighborhood of $s_*$, and so is smooth there.

-   The case with $c(s_*)\in X\times B$, and $x(s_*)\notin A$ is similar to the second case above.

For the last part of the theorem, suppose that $(u, H)$ represent $(X, A)$ as an SDR pair. If we replace $u$ by $u'=\frac{1}{2}u$, then $(u', H)$ also represent $(X, A)$ as an SDR pair. Making the above constructions now with $u'$ in place of $u$, it follows that $w(x, y)< 1$ for all $(x, y)$ and so $Q(1, x, y)\in (X\times
B)\cup (A\times Y)$. This completes the proof. [$\square$]{}

Cofibrations
============

In this section, we showThe regulation of biological activity at the cell surface is achieved through a variety of processes including recycling, shedding, and protein-protein and protein-membrane interactions. While protein activities are often studied in isolation, methods by which activities could be evaluated in membrane-like environments provide greater insight into *in vivo* behaviors. Membrane type 1 matrix metalloproteinase (MT1-MMP) is a type I transmembrane cell-surface protease that has been implicated in numerous pathologies[@b1][@b2][@b3]. MT1-MMP possesses a multidomain structure, encompassing a signal peptide, propeptide, catalytic (CAT) domain, hinge region (linker 1), hemopexin-like (HPX) domain, stalk region (linker 2), transmembrane domain (TM), and cytoplasmic tail (CT) ([Fig. 1](#f1){ref-type="fig"}). Active MT1-MMP ([Fig. 1](#f1){ref-type="fig"}) has been ascribed a variety of cell surface activities, with one of the most prominent being that of a pericellular collagenase. MT1-MMP


with the isolated HPX domain ([Fig. 3D](#f3){ref-type="fig"}).

The NMR data were used to calculate a structural model reproducing the transient interaction of the HPX domain with the membrane-mimicking bilayer ([Figure S12A,C](#S1){ref-type="supplementary-material"}). The residues experiencing the largest variation in signal intensity were used as "active residues" in docking calculations with a membrane model. The same NMR data were then used to calculate a structural model between the HPX•THP complex recently reported (pdb: 2MQS) and the membrane ([Figure S12B,D](#S1){ref-type="supplementary-material"}). The role of the residues experiencing a decrease in signal intensity in the presence of CHAPS alone was analyzed by performing different sets of docking calculation in which they were included ([Figure S12A,B](#S1){ref-type="supplementary-material"}) or excluded ([Figure S12C,D](#S1){ref-type="supplementary-material"}) as "active residues". It is interesting to note that in the docking models generated startingthe isolated domains with that of sMT1-MMP and confirmed with the triple resonance experiments 3D HNCA and 3D CBCA(CO)NH. NMR experiments were performed at 298 K and acquired on DRX 500 MHz and Bruker AVANCE spectrometers operating at 700, 800, and 950 MHz and equipped with triple resonance cryo-probes. The experiments for the determination of ^15^N longitudinal and transverse relaxation rates and ^1^H-^15^N NOE were recorded at 298 K and 700 MHz on ^15^N-enriched samples of isolated CAT and HPX domains. The ^15^N longitudinal relaxation rates (R~1~) were measured using a sequence modified to remove cross-correlation effects during the relaxation delay[@b51]. Inversion recovery times ranging between 2.0 and 3000 ms, with a recycle delay of 3.5 s, were used for the experiments. The ^15^N transverse relaxation rates (R~2~) were measured using a Carr-Purcell-Meiboom-Gill (CPMG) sequence[@b51][@b52],


a humidified atmosphere. Cells were then detached from the culture flask with trypsin-EDTA 0.05% (Gibco) and resuspended in 20 mL DMEM containing 10% FBS to inactivate trypsin. Cells were gently centrifuged (5 min, 800 × g) and washed with PBS (137 mM NaCl, 2.7 mM KCl, 10 mM Na~2~HPO~4~, 1.8 mM KH~2~PO~4~, pH 7.2). Cells were counted with a Burker chamber and 10 μL of the suspension containing 2.0 × 10^6^ cells was added to the MT1-MMP HPX domain solution for the NMR study.

Kinetic analysis of MT1-MMP
---------------------------

The proenyzme form of sMT1-MMP (designated pro-sMT1-MMP) was obtained from EMD Millipore (catalog \# CC1043). The "cartoon" pro-sMT1-MMP included the MT1-MMP sequence from Met1 to Glu532 with a single point mutation, where Ser466 was changed to a Pro. The S466P mutation in MT1-MMP was generated by PCR using the following primers: ctcctagagggccattcatggg. Thescaled down to 0.01, and the number of molecular dynamics steps for the first two parts of the protocol (rigid-body high temperature dynamic and slow cooling annealing in the semi-flexible refinement) was set to 0 to favor the interaction with the lipids. During the rigid docking calculations, 1000 complexes were generated, then 200 structures were selected for the semi-flexible simulated annealing in torsion angle space, and finally refined in Cartesian space with explicit solvent.

A model of sMT1-MMP was obtained using Modeller[@b60]. The X-ray structures of the isolated domains (pdb 3MA2 and 3C7X for CAT and HPX, respectively) and the reciprocal orientation of the two domains in the X-ray structure of MMP-12 (pdb 3BA0) were used as a template.

Additional Information
======================

**How to cite this article**: Cerofolini, L. *et al*. Bilayer


A need has long existed for lasers that can be tuned to any wavelength within a given band. Until the present invention, it has only been possible to tune lasers, for example diode lasers operating in the 1.3 micron band or the 1.55 micron band, that are the focus of experimentation for optical fiber communication systems, over a range of one-thousandth of a micron, that is to say a range of perhaps a nanometer. Since such optical fiber communication systems typically employ a multiplicity of individual channels, each separated from its neighboring channels by at least a nanometer, a multichannel system has required a multiplicity of different lasers, each one fabricated to operate at one of the required wavelengths. Three types of lasers have been used in suchorder for the device to exhibit lasing, the total round trip path length, from the diode's rear surface, out to the grating's effective center of reflection and back to the diode's rear surface must be a whole number of wavelengths, or a whole number of wavelengths plus one-half wavelength, depending on the phase shift upon reflection.
However, the patent also states that the laser's output wavelength can be tuned by changing the effective periodicity of the feedback grating alone, and suggests two methods for accomplishing such a change. The patent does not admit the necessity of also changing the cavity length in proportion to the change in feedback wavelength, nor does it suggest any means of achieving this essential requirement.
In the absence of some such means, any wavelength tuning


other groups.

In order to offer a wealth of choices and a comforting experience, Coyle Funeral Home partners with many local vendors and businesses. They joined the Toledo Regional Chamber of Commerce more than 25 years ago and are also a part of the University of Toledo Family Business Center. For nearly the duration of their businesses, Coyle has relied on Florian Insurance, another five generation community business, to provide coverage. Coyle prides itself on honoring the fire, police and military veterans with special services, like the Last Alarm, 21 gun salute, and other fitting ceremonies.

Vintage Procession

Vintage Hearse

AWARDS

2011 - 20 under 40

2013 - Torch Award (BBB)

2013 - 2014 Peer Award (Outlook Group)

2013 – President’s Award Physicians Mutual

2015 – Best Block of preneed business – National Award from The Outlookcertificates from
legitimate CAs. Others are stealing poorly-protected private keys
from legitimate businesses and using those keys to sign
malware.

SigCheck’s command-line parameters provide numerous options for
performing verifications, specifying the files to scan, and formatting
output. The syntax is shown here, followed by Table 8-1, which provides a summary of the parameters:

Table 8-1 SigCheck Command-Line Parameters

Specifies the file or directory to process. It can include wildcard characters.

Signature Verification

–i

Shows the catalog name and image signers.

–r

Checks for certificate revocation.

–u

Reports unsigned files only, including files that have invalid signatures.

–c

Looks for a signature in the specified catalog file.

Which Files to Scan

–e

Scans executable files only. (It looks at the file headers, not the extension, to determine whether a file is an executable.)

–s

Recurses subdirectories.

Additional File Information

–a

Shows extended version information.

–h

Shows file hashes.

–m

Shows the manifest.

–n

Shows the file version number only.

Output Format

–v

CSV


from the CA certificates in its chain.

By default, SigCheck does not check whether the signing
certificate has been revoked by its issuer. To verify that the
signing certificate and the certificates in its chain have not been
revoked, add –r to the command
line. Note that revocation checking can add significant network
latency to the signature check, because SigCheck has to query
certificate revocation list (CRL) distribution points.

To focus your search only for unsigned files, add –u to the command line. SigCheck then scans
all specified files, but it reports only those that are not signed
or that have signatures that cannot be verified.

Windows maintains a database of signature catalogs to enable
quick lookup of signature information based on a file hash. If you
want to verify a file against a catalog file that is not registered
in thepackage org.nd4j.linalg.api.ops.impl.layers.convolution;

import lombok.Builder;
import lombok.Getter;
import lombok.extern.slf4j.Slf4j;
import org.nd4j.autodiff.samediff.SDVariable;
import org.nd4j.autodiff.samediff.SameDiff;
import org.nd4j.imports.NoOpNameFoundException;
import org.nd4j.linalg.api.ndarray.INDArray;
import org.nd4j.linalg.api.ops.DynamicCustomOp;

import java.util.ArrayList;
import java.util.Arrays;
import java.util.List;

/**
 * Upsampling operation
 */
@Slf4j
@Getter
public class Upsampling extends DynamicCustomOp {

    protected int scaleFactor;

    @Builder(builderMethodName = "sameDiffBuilder")
    public Upsampling(SameDiff sameDiff, SDVariable[] inputs,INDArray[] inputArrays, INDArray[] outputs,boolean inPlace, int scaleFactor) {
        super(null,sameDiff, inputs, inPlace);
        this.scaleFactor = scaleFactor;
        if(inputArrays != null) {
            addInputArgument(inputArrays);
        }

        if(outputs != null) {
            addOutputArgument(outputs);


    const string TableNamePrefix = "AspNet";
        var tableName = entityType.Relational().TableName;
        if (tableName.StartsWith(TableNamePrefix))
            entityType.Relational().TableName = tableName.Substring(TableNamePrefix.Length);
    }
}

Update (EF Core 3.0+): Use entityType.GetTableName() and entityType.SetTableName(...) extension methods.

with binaries on hw
#
proc run_boot_dir {binaries} {

	# generate static ACPI report for platform driver on Muen
	if {[have_spec "muen"]} {
		set fh [open "bin/acpi" "WRONLY CREAT TRUNC"]
		puts $fh "<acpi><bdf start=\"0\" count=\"16384\" base=\"0xf8000000\"/><drhd/></acpi>"
		close $fh
	}

	#
	# Build bootstrap, the core object, and the dynamic linker on demand
	#
	# If those parts were imported from the depot, the build step is skipped.
	#
	set bootstrap_arg ""
	set core_arg      ""
	set ld_arg        ""

	if {![file exists [run_dir]/genode/ld.lib.so]}      { set ld_arg        lib/ld/hw    }
	if {![file exists [run_dir]/genode/core-hw.o]}      { set core_arg      core/hw      }
	if {![file exists [run_dir]/genode/bootstrap-hw.o]} { set bootstrap_arg bootstrap/hw }

	set build_args


unzipped her skirt a little thinking that this
would give her enough slack to raise her leg. Again she tried to make
the step onto the bus only to discover she still could not make the
step.

So, a little more embarrassed, she once again reached behind her and
unzipped her skirt a little more. And for a second time she attempted
the step and once again, much to her dismay, she could not raise her leg
because of the tight skirt.

So, with a coy little smile to the driver, she again unzipped the
offending skirt to give a little more slack and again was unable to make
the step.

About this time the big Texan that was behind her in the line picked her
up easily from the waist and placed her lightly on the step of theknow what they were saying. Then he heard footsteps coming up the stairs, and his door opened.

"Billy," his father began in that lecturing-father tone, "Your mother says you've been acting badly lately. Would you like to tell me what you've done?"

"Dad, I haven't done anything! I just don't know what the Purple Wombat is!"

"You...don't know what the Purple Wombat is. Well, in that case, you can just stay in this room all night, mister. And forget about dinner!"

Billy's father slammed the door and stormed off. Billy collapsed on his bed, crying his eyes out. He spent the next several hours that way -- lying there, crying, wishing he would wake up.

Then, in the middle of the night, he heard a voice. It said: "Billy. I am the Purple


Book. We are always looking to improve our service and would
value your opinion," said the receptionist.

"Ok I will...thanks!" replied Mary, who then checked out, paused
awhile, then scribbled a comment into the book. Waving, she left to
continue her journey.

Curious, the receptionist picked up the book to see the comment Mary
had written. She wrote:

"Supercauliflowercheesebuteggswerequiteatrocious!!!!"

9/06/01
A drunk walks into a bar and says to the bartender (with a drunken slur), "bartender, buy everyone in the house a drink, pour yourself one, and give me the bill."

So, the bartender does just that and hands the man a bill for $37.00.

The drunk says, "I haven't got it."

The bartender slaps the guy around a few times then threw him out into the street.

The very next day the same drunk walks into the bar and onceis technically demanding due to sacral complex anatomy, it is more challenging in dysmorphic sacra \[[@bib0095]\]. Wide variation of sacral morphology exists in up to 40% of general population, all of which does not allow for safe passage of trans-osseous screw placement \[[@bib0070],[@bib0100]\]. Consequently, misplaced instrumentation can occur in 29% of dysmorphic sacra, compared to 12% in sacra without dysmorphism \[[@bib0035]\]. The introduction of intraoperative navigation allowed surgeons to accurately visualize the sacrum, and to immediately assess screw trajectory. In a recent systematic review \[[@bib0035]\], CT navigation was found to be the modality with the lowest malposition rate (0.1%). However, aberrant insertion still occurs in dysmorphic sacra with no significant difference in risk of cortical breach between standard imaging and navigation \[[@bib0070]\].

Despite the common incidence of malposition and


or poor.

But, even if you understand the theory, the practice is difficult. Controls are generally scattered throughout the configuration menus and tabs, requiring a thorough search for all the settings that you require or want. Should you fail to set up encryption properly, usually you receive no feedback about why.

The closest to an easy process is Enigmail, a Thunderbird extension that includes a setup wizard aimed at beginners. But you have to know about Enigmail to use it, and the menu it adds to the composition window buries the encryption option one level down and places it with other options guaranteed to mystify everyday users.

No matter what the desktop, the assumption is that, if you want encrypted email, you already understand it. Today, though, the constant media referencesOnly networks having the free hotels you do given offer based.

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The bound-state wavefunctions of $V^{(-)}(x)$ can be written as $$\begin{gathered}
  \psi^{(-)}_{\nu}(x)  \propto \frac{(1-z)^{\alpha_{\nu}/2} (1+z)^{\beta _{\nu}/2}}{g^{(A,B)}_m(z)} y^{(A,B)}_n(z),
       \qquad n=m + \nu + 1, \nonumber\\
  \nu  =-m-1, 0, 1, \ldots, \nu_{\max},  \nonumber\\
  \alpha_{\nu}  = A-1-\nu + \frac{B}{A-1-\nu}, \qquad \beta_{\nu} = A-1-\nu - \frac{B}{A-1-\nu},
   \label{eq:psi-typeIII}\end{gathered}$$ where $y^{(A,B)}_n(z)$ is an $n$th-degree polynomial in $z$. For the ground state, on one hand, we have $$\begin{gathered}
  \psi^{(-)}_{-m-1}(x)   \propto \left(\phi^{\rm III}_{A-1,B,m}(x)\right)^{-1} \propto \frac{(1-z)^{\alpha_{-m-1}/2}
       (1+z)^{\beta _{-m-1}/2}}{g^{(A,B)}_m(z)},  \qquad
  y_0^{(A,B)}(z)  =1.
 $$ For the excited states, on the other hand,


may also take the value $-m-1$, giving rise to the ground-state energy and wavefunction $$\begin{gathered}
  E^{(-)}_{-m-1} = E^{\rm III}_{A+1,B,m} = - (A-m)^2 - \frac{B^2}{(A-m)^2}\end{gathered}$$ and $$\begin{gathered}
  \psi^{(-)}_{-m-1}(x) \propto \left(\phi^{\rm III}_{A+1,B,m}(x)\right)^{-1} = \frac{(z-1)^{\alpha_{-m-1}}
  (z+1)^{\beta_{-m-1}}}{g^{(A,B)}_m(z)},\end{gathered}$$ corresponding to $y^{(A,B)}_0(z) = 1$.

Equations (\[eq:psi-typeII-bis\]) and (\[eq:y-typeII-bis\]) now provide us with the excited-state wavefunctions of $V^{(-)}(x)$. As a consequence, equation (\[eq:psi-0-typeII-bis\]) describes the first-excited wavefunction. In accordance with such a property, it can be readily checked from equations (\[eq:zeros-3\]), (\[eq:zeros-5\]), and (\[eq:zeros-6\]) that its polynomial part $g^{(A+1,B)}_{m+1}(x) = P^{(-\alpha_{-m-1}, -\beta_{-m-1})}_{m+1}(z)$ has one zero in the interval $(1, \infty)$ for the choice of parameters pertinent to type III potentials.

Equations (\[eq:V-rat\]) and (\[eq:V-rat-2-bis\]) yield an example of type III potential corresponding to $m=2$ if we replace $A$, $B$, and $\tanh x$ by $-A$, $-B$, and $\coth x$,$A$ is similar to that observed for the corresponding conventional potential, which is known to be translationally SI [@cooper], but the modification in the degree $m$ points to the existence of an enlarged SI property, valid for some rational extensions.

Furthermore, it is worth observing that the first step from $V^{(+)}(x)$ to $V^{(-)}(x)$ (using broken SUSYQM) and the second one from $\bar{V}^{(+)}(x) = V^{(-)}(x)$ to $\bar{V}^{(-)}(x)$ (employing unbroken SUSYQM) can be put together [@bagchi; @andrianov; @bagrov; @aoyama; @fernandez] to arrive at a reducible second-order SUSYQM transformation from a conventional potential to an extended one, $V^{(m-1)}_{A-1,B,\rm{ext}}(x)$, $V^{(m-1)}_{A+1,B,\rm{ext}}(x)$, or $V^{(m+1)}_{A+1,B,\rm{ext}}(x)$. In each case, the same result can be obtained along another path by combining the usual unbroken SUSYQM transformation relating two conventional potentials with translated parameter $A$ with a broken one


and

seizures by government officials. U.S. Const. amend. IV; Wiede, 214 S.W.3d at

24. It is undisputed that this was a warrantless arrest, so the burden of proof

shifted from Appellant to the State, which was then required to establish that the

search or seizure was reasonable. Amador, 221 S.W.3d at 672–73; Torres v.

State, 182 S.W.3d 899, 902 (Tex. Crim. App. 2005); Ford v. State, 158 S.W.3d

488, 492 (Tex. Crim. App. 2005).

          The parties conflate reasonable suspicion and probable cause in their

briefs.       A detention, as opposed to an arrest, may be justified on less than

probable cause if a person is reasonably suspected of criminal activity based on

specific, articulable facts. Terry v. Ohio, 392 U.S. 1, 21, 88was traveling. One of our sister courts has

held that in circumstances such as these, officers are not required to use radar to

determine that a driver is speeding. See Icke v. State, 36 S.W.3d 913, 915–16

                                         13
(Tex. App.—Houston [1st Dist.] 2001, pet. ref’d). In Icke, the court held that

reasonable suspicion was shown by the arresting officer’s testimony that he

formed the opinion that the defendant was speeding based upon his experience

and without the use of radar. Id. Although the officer confirmed his suspicion

through the use of radar, the court noted


first subissue.

III. Unsafe lane change

      Appellant’s second subissue argues that Officer Steppe did not have

reasonable suspicion or probable cause to detain Appellant for violating section

545.060 of the transportation code. See Tex. Transp. Code Ann. § 545.060

(West 2011) (providing that a driver “shall drive as nearly as practical entirely

within a single lane and may not move from the lane unless that movement can

be made safely”). Because in overruling Appellant’s first subissue we have held

that reasonable suspicion existed to stop and detain Appellant for speeding, we

do not need to address his second subissue.

                                YELLOWMAN

Reggae Calypso Lyrics

His eyes are closed his face pale asleep
on the ground a newspaper reads
the blood has spilled again
and you just dream my yellowman
yellowman
The angels burn a torch to keep us warm
His lungs are wide awake but he won't breathe
He spits out the ocean and we dream
like goldfish in a bowl
They think we're free
yellowman
You're tying rocks to clouds to stay above the crowds
The angels burn a torch to keep us warm
the blood has spilled again
and you just dream
yellowman
You never see the bloodstains on the battlefield
The angels burn a torch to keep us warm


2015, Mr. Trump announced he was running for President of the United States. He was totally confident in his ability to conquer those who stood in his way of the Presidency. Why was he so confident? He did his research.

From the very beginning of his campaign, he knew exactly who his target demographic was & how to communicate with them. He provided clarity about what he was all about and did not waiver from this message. He established brand clarity early on, which allowed voters to easily digest his views and decide to get behind what he stood for.

Brand leaders of startups, small businesses, & large organizations must all realize that – “Clarity & Consistency are key in a brand’s success.”

Throughout our Brand Focus coaching program at CulturalThe posterior transpedicular approach for circumferential decompression and instrumented stabilization with titanium cage vertebrectomy reconstruction for spinal tumors: consecutive case series of 50 patients.
A retrospective case series. To demonstrate the feasibility, safety, and results of the posterior transpedicular approach for circumferential decompression and instrumented reconstruction of thoracolumbar spinal tumors. Patients presenting with spinal tumor disease requiring 3-column instrumented stabilization are typically treated with a combined anterior and posterior surgical approach. However, circumferential decompression and instrumented stabilization may also be achieved through a single-stage, midline posterior transpedicular approach. Fifty consecutive patients (27 women and 23 men) underwent surgery between 2003 and 2010 at a single institution by the senior author. Mean age was 55.9 years (range, 25-79 yr).Single or multilevel, contiguous subtotal vertebrectomy was performed ranging from T1 to


Q:

NSKeyedUnarchiver.unarchiveTopLevelObjectWithData is obsoleted in Swift 4

I tried to implement a fork of AwesomeCache that implements unarchiveTopLevelObjectWithData in Swift 4:
if let data = NSData(contentsOfFile: path) {
    do {
        possibleObject = try NSKeyedUnarchiver.unarchiveTopLevelObjectWithData(data as NSData) as? CacheObject
    }
    catch {}
}

But Xcode is angry at me now, and says:
'unarchiveTopLevelObjectWithData' was obsoleted in Swift 4 (Foundation.NSKeyedUnarchiver)

Mean, imo, because it doesn't tell me what it's been replaced with (if anything?), and the documentation is rather... vacant.
So what do I use instead?

A:

Agree with you, NSData is not Data, an improvement could be:
    if let nsData = NSData(contentsOfFile: path) {
        do {
       The present invention relates to a rock drilling tool, comprised of a drill body and a reamer mounted thereon for radial extension and retraction.
In known drilling tools of the above-mentioned type, drawbacks result from screw thread connections, for example between the guiding means and the part which carries the reamer, because there always occur energy losses in threaded joints which transfer impact energy.
Another known tool is shown in applicant's U.S. Pat. No. 5,284,216 wherein the shank and the drill bit constitute an entity on which a guide is arranged. However it has been experienced that the known tool comprises a number of drawbacks; the reamer cannot easily be exchanged, the impact energy cannot be maximally utilized, the position of the grooves cannot be placed optimally, and locking means


sometimes violent. The person has great difficulty with communication and daily activities, and sometimes wants to harm or kill himself (or herself).Relapse: Ambulatory care0.778Death1.000

### Years of life lost (YLL) {#Sec8}

When a patient dies in the model the Years of Life Lost (YLL) are calculated as the number of deaths at age a and month t (N~(a,t)~) multiplied by the Years of Life Lost at age a (L~(a)~).$$\documentclass[12pt]{minimal}
                \usepackage{amsmath}
                \usepackage{wasysym}
                \usepackage{amsfonts}
           versus burden result that one would expect \[[@CR9]\].

While this study provides a first insight in the holistic quantification of the Human Health benefit and burden of a full health care pathway, these findings should be validated and contrasted with research based on real-world data in different disease areas and in multiple countries.

**Additional files**
====================

 {#Sec21}

Additional file 1:Background information on model inputs, assumptions and limitations, literature reviews, Life Cycle Assessment results by midpoint category and sensitivity analysis. (DOCX 4880 kb) Additional file 2:Transition probability matrices for the Markov model. (XLSX 14 kb)

AoP

:   Area of Protection

CEA

:   Cost-Effectiveness Analysis

DALY

:   Disability-Adjusted Life Years

LCA

:   Life Cycle Assessment

LCI

:   Life Cycle Inventory

LCIA

:   Life Cycle Impact Assessment

NHS SDU

:   National Health Service Sustainable Development


results and provided critical revisions to the final manuscript. All authors read and approved the final manuscript.

Janssen Pharmaceutica.

Role of the funder: the Janssen Pharmaceutica Environment, Health, Safety and Sustainability and Health Economics departments have had a role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

Flemish Innovation and Entrepreneurship, VLAIO.

Role of the funder: the VLAIO did not have a role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

The work was jointly funded by previously mentioned entities in the form of a VLAIO, Baekeland mandate grant (no. 140249).

All data generated or analyzed during this study for the Markov model are included in this published article and its supplementary information files.

Theexercise, sleep, things like that. They’re very progressive. How that translates to the field, we don’t know. They do tend to like platoons, so we’ll see that in the outfield corners. And the Kendrys Morales signing was very sensible. They’re very right-handed, and as a switch-hitter with power, he’ll help balance that. They got Steve Pearce, too, and he’s a versatile guy who can hit, but he’s had arm issues, so that concerns me. They’ve got a lot of solid two-way guys like Josh Donaldson, Troy Tulowitzki, Kevin Pillar and Russell Martin, who does such a great job with that staff. If he can work his magic with Francisco Liriano and get him to throw strikes the way he did in Pittsburgh, that rotation is really strong 1


Thursday, May 24, 2012

I hit the big Five O on Tuesday. I'm really thankful for my renewed health and could not help but reflect what life was like for me just a year ago.

Wow, time really flies. I can't believe that 2012 is almost half gone.

I have some thoughtful friends that made my birthday extra special and I wanted to share some pictures of their gifts to me.
First, I received a lovely package from my friend Arcadia in France. Among the things she sent was this lovely cross stitch that she created into a very cute purse.

This past Saturday, I opened my mailbox to find this lovely cross-stitched card and biscornu kit from my friend Nicola in England.

On Monday I received this lovely stitched piece and a Frenchbut I will give you my recommendation now just in case some of you have been “on the fence”.

In short, Yes. You SHOULD go out and get the game now! If you are a Star Wars fan and want to play an immersive single player Star Wars Storyline, then go out and get the game. If you enjoyed Battlefront I, you’ll like the improvements, go out to get the game now. If you want to support EA, a solid game company who has had hits across multiple genres, buy the game. EA’s stock prices actually fell due to that Nerds rumor. A drop in stock means less games being made and that leads to job loss. Way to go Nerd!

Battlefront 2 is a solid game. Don’t listen to


pitch during the warm up and it affected my performances

When I was 21 I was super fit and pace was the main part of my game, but on this day I was tired after one run, my legs felt like they were cramping up and I had zero energy. I had a bad game, and it was the beginning of the end for me. This was the start of 10 years of this feeling and the start of what was a downward spiral in my career.

The dressing room and training ground are tough places to be if you have anxiety or depression. There is no place to hide and when I was young and at Queen of the South I found it difficult. I remember feeling so nervousinjuries and weeks missed, I felt nervous and in the first half I got hammered by the winger. I had jelly legs, no energy, sore head, the usual symptoms. I remember the manager saying my fitness was a disgrace, and it probably looked like that. I wish I could have told him the truth.

Looking back I wish I had asked for help.

My fitness was high but my anxiety was the issue. I hardly played again for Falkirk apart from a decent spell in February and March, and I knew my time there was coming to an end. My old problems had returned, or rather had never gone away.

I have learned to deal with the feelings over the years, but they never really go away. I can force food


the Bitcoin days destroyed indicator.

Bitcoin days destroyed is a measure of the worth of every BTC transaction, taking into consideration how prolonged it has been because the cash concerned final moved.

Previously, jumps above $10,000 resulted in a rise inside the Bitcoin days destroyed metric, suggesting that long-term holders had been utilizing the chance to commerce or promote.

So far, however, the weekend’s optimism has but to repeat the development.

“In contrast to the last two multiplication $BTC hit $10,000 USD, we haven’t seen an increase in #Bitcoin Days Destroyed today,” Glassnode summarized.

Weekend crypto beneficial properties shock markets

Cautious optimism that Bitcoin is destined for big ranges however has turn into a theme in itself amongst merchants in latest months.

When PayPal sparked rumors of crypto acceptance in June, for instance, discuss instantlyPricing & Availability

For Zip Code:

For Zip Code:

Sorry, this item is out of stock

Subscribe to be notified when this species become avaliable, and stay up to date with newly added species and special offers.

Description

Antennaria virginica

Also known as:

shale barren pussytoes

,

pussytoes

,

pussy toes

Scientific Synonyms:

Antennaria neglecta

Description

Endemic to a limited area of the Appalachians, the shale-barren pussytoe is a low spreading semi deciduous plant forming attractive colonies of half dollar size rosettes of small silvery leaves and fuzzy, white flower clusters atop 4"-8" stems. The spent flowers dry out and retain an attractive papery appearance.

Cultivation

Antennaria virginica is an ideal groundcover for poor, shaley, or sandy soil. It can be a welcome addition to any rock garden. It prefers dry conditions with a southern or western exposure. Part sun to full sun. Spring bloom time,


abstract the creation of the step

At this point we have much less code than the first example, the steps are declared as one-liners and we repeat only what we know that may change.

One could even argue that jQuery is not enough of a solution for this and we should start our application with Angular, React, VueJS, etc. because it’s more likely that the application will evolve and the cost of changing it later will be much bigger...

Wait! Why are we talking about frameworks, queues, and steps?

Let's go back to the original requirements:

Build 3 clickable images where clicking on each one of them will cause the one being clicked to become bigger double the original size and after 1 second to become smaller again to the original size.

Was thisQ:

URL Redirect / URL Masking

I have a page.
http://sciconference.net/viewjc.php?id=c5
I want when some body comes on this page the URL Bar shows the url
http://sciconference.net/ICEEC
means URL masking... I try .htaccess but no success please help me out.

A:

Try creating .htaccess and putting the following in it:
<IfModule mod_rewrite.c>

RewriteEngine On
RewriteRule ^ICEEC$ viewjc.php?id=c5 [L]
RewriteRule ^ICEEC/$ viewjc.php?id=c5 [L]

</IfModule>

Make sure that the viewjc.php is at the same directory as your .htaccess
If you're just trying to change URL address bar when someone visits particular page of your website, add this to your PHP code page:
if ( $_SERVER['REQUEST_URI'] == '/viewjc.php?id=c5') {
    echo '<script type="text/javascript">window.history.pushState("", "", "/ICEEC");</script>';
}

Everytime when a user goes to viewjc.php?id=c5 your URL will be changed.
Besides you could again use .htaccess for doing that!