for never telling me.

She got quiet.

Then it hit me why she’d never told me. Because Abe’s story ends in tragedy.

By all accounts, Abe, who was mayor of Atlanta for awhile, was a gregarious, larger-than-life guy. But he and Sam were being audited by the IRS. There were rumors, later confirmed by Bishop Hardt, that the audit was a maneuver by political rivals, designed to bring scorn and embarrassment to the Mayses.

Although the IRS audit was resolved, Abe took it hard and committed suicide in the early 1960s, around the time I was born. The grocery store closed by the time I was 6 or 7.

Which is why, despite Ches Mays’ conversion that changed the course of his family, it sort of feels like the end of the storydramatic situation where maybe books can do something. I’m not sure I’m going to win, but I’m sure this is the way to change things.

What do you find most worrying in Italy at the moment?

This is a dangerous government, which risks being the first clearly authoritarian government in Europe [this century]. Salvini’s words are close to the words of Orbán, of Putin. He based his whole campaign on attacking migrants, while never saying anything against the mafia, of which he understands nothing.

The word “fascism” should be used with caution, but when politicians like Salvini start quoting Mussolini (“so many enemies, so much honour”) is it appropriate?

I realise that the word “fascist” denotes a specific historical period, but there are some expressions, some hints, that bring to mind a


a lot. I would sometimes like to not be who I am any more, to have a decent life, but I do it – some people think out of ambition, others narcissism – for honour. A word that fascists have plundered from us. For me, it’s an honour to fight those who are running the greatest defamatory campaign of recent years, against migrants. I do it knowing full well that it generates hatred, isolation, contempt. There’s no advantage: the easiest thing would be to stay quiet. But I go on.

Which writers or investigative journalists do you admire most?

I have a great respect for Turkish journalist Can Dündar. He was arrested for revealing in his newspaper [Cumhuriyet] that Erdogan was secretly taking part in the war in Syria. Ithan London, Algiers than Berlin. It’s an aberration, that the south, the heart of the Mediterranean, can’t be a shared territory. Maybe that’s what I was saying: this capacity to be convivial. This is an Italian quality that rancour, Salvini, and the hell we’re living in still haven’t erased.


see President Obama pursue an idea we've long believed in," said Senate Majority Leader Mitch McConnell, a long-time White House foe, who once said his top priority was making Mr Obama "a one-term president".

Image copyright EPA Image caption Senate Majority Leader Mitch McConnell, a long-time political nemesis of Mr Obama, thanked the president for his efforts

Senate Finance Committee Chairman Orrin Hatch, a Republican, said the bill was "the most important bill that will pass the Senate this year".

The bills's passage - made all but inevitable after it cleared a more stringent procedural hurdle on Tuesday - incensed many Democrats.

Speaking before Wednesday's vote, Senator Sherrod Brown said the bill would lead to "corporate handouts, worker sell-outs" in the way that he said the North American Free Trade Agreement (Nafta)\uCC3E\uC9C0 \uBABB\uD588\uC2B5\uB2C8\uB2E4.
serviceTypeNotSet=\uC11C\uBE44\uC2A4 \uC720\uD615\uC774 \uC62C\uBC14\uB974\uAC8C \uAD6C\uC131\uB418\uC9C0 \uC54A\uC558\uC2B5\uB2C8\uB2E4.
serviceTemplateNotFound=\uC11C\uBE44\uC2A4 \uD15C\uD50C\uB9AC\uD2B8 [{0}]\uC774(\uAC00) \uC874\uC7AC\uD558\uC9C0 \uC54A\uC2B5\uB2C8\uB2E4. INSTALL_ROOT \uB4F1\uC758 \uC124\uC815 \uD658\uACBD\uC5D0 \uBB38\uC81C\uAC00 \uC788\uC2B5\uB2C8\uB2E4.
notSolaris10=\uD604\uC7AC \uD50C\uB7AB\uD3FC, OS: {0} \uBC84\uC804: {1}\uC774(\uAC00) Solaris 10\uC774 \uC544\uB2D9\uB2C8\uB2E4. \uC774 \uAE30\uB2A5\uC740 Solaris 10 \uC678\uC758 \uD50C\uB7AB\uD3FC\uC5D0\uC11C\uB294 \uC9C0\uC6D0\uB418\uC9C0 \uC54A\uC2B5\uB2C8\uB2E4.
noPermissionToCreateManifest=\uC0AC\uC6A9\uC790 [{0}]\uC5D0\uAC8C\uB294 [{1}]\uC5D0\uC11C \uC11C\uBE44\uC2A4 \uB9E4\uB2C8\uD398\uC2A4\uD2B8 \uAD00\uB828 \uD30C\uC77C \uBC0F \uB514\uB809\uD1A0\uB9AC\uB97C \uC0DD\uC131\uD560 \uAD8C\uD55C \uC124\uC815\uC774 \uC5C6\uC2B5\uB2C8\uB2E4. SMF \uC9C0\uCE68\uC5D0 \uB530\uB77C \uC774 \uAD6C\uC870\uAC00 \uD544\uC694\uD569\uB2C8\uB2E4. \uC218\uD37C\uC720\uC800\uAC00 \uB418\uC5B4 \uC774 \uC791\uC5C5\uC744 \uC218\uD589\uD558\uAC70\uB098 \uC2DC\uC2A4\uD15C \uAD00\uB9AC\uC790\uC5D0\uAC8C \uBB38\uC758\uD558\uC5EC \uAD00\uB828 \uAD8C\uD55C \uC124\uC815\uC744 \uC5BB\uC740 \uD6C4 \uB2E4\uC2DC \uC2DC\uB3C4\uD558\uC2ED\uC2DC\uC624.
noSmfAuth=\uC0AC\uC6A9\uC790 [{0}]\uC5D0\uAC8C \uC774 \uC2DC\uC2A4\uD15C\uC5D0\uC11C SMF \uC11C\uBE44\uC2A4\uB97C \uC0DD\uC131\uD558\uACE0 \uAD6C\uC131\uD560 \uC218 \uC788\uB294 \uAD8C\uD55C [solaris.smf.*]\uAC00 \uC5C6\uC2B5\uB2C8\uB2E4. \uC0AC\uC6A9\uD560 \uC218 \uC788\uB294 \uC778\uC99D\uC740 [{1}]\uC785\uB2C8\uB2E4.\nsmf_security(5), rbac(5)\uB97C \uCC38\uC870\uD558\uC2ED\uC2DC\uC624.\n
missingParamsInFile=\uD544\uC218 \uC591\uC2DD\uC5D0\uC11C [{0}](\uC73C)\uB85C \uC9C0\uC815\uB41C passwordfile\uC5D0 \uC18D\uC131 [{1}]\uC774(\uAC00) \uD3EC\uD568\uB418\uC5B4 \uC788\uC9C0 \uC54A\uC2B5\uB2C8\uB2E4. \uC774 \uD30C\uC77C\uC758 \uBCC4\uB3C4 \uC904\uC5D0 [{1}=value]\uB97C \uCD94\uAC00\uD55C \uD6C4 \uBA85\uB839\uC744 \uB2E4\uC2DC \uC2E4\uD589\uD558\uC2ED\uC2DC\uC624.
serviceNameExists=\uC774 \uC2DC\uC2A4\uD15C\uC5D0\uC11C [{0}](\uC774)\uB77C\uB294 \uC774\uB984\uC758 SMF \uC11C\uBE44\uC2A4\uAC00 [svcs -a] \uBA85\uB839\uC5D0\uC11C \uD45C\uC2DC\uB418\uB294 \uAC83\uACFC \uAC19\uC774 \uC874\uC7AC\uD569\uB2C8\uB2E4. \uC11C\uBE44\uC2A4\uC5D0 \uC81C\uACF5\uB418\uB294 \uB2E4\uB978 \uC774\uB984\uC73C\uB85C \uC11C\uBE44\uC2A4\uB97C \uB2E4\uC2DC \uC0DD\uC131\uD574 \uBCF4\uC2ED\uC2DC\uC624.
runtimeStatusToString={0}\uC740(\uB294) {1}\uC785\uB2C8\uB2E4.
fileNotFound={0} \uD30C\uC77C\uC774 \uC5C6\uC2B5\uB2C8\uB2E4.
error=\uC624\uB958
runtimeStatusToStringStopCluster.alreadyStopped=\uD074\uB7EC\uC2A4\uD130\uB9C1\uB41C \uC778\uC2A4\uD134\uC2A4 {0}\uC774(\uAC00)


the needle, it comes into contact with the apex of the pyramid and gets transferred due to the weight of the droplet. 20 drops of HA-MA solution were dropped on the tip of the nanofibril canopy. The HA-MA does not readily seep through the nanofiber matrix due to the hydrophobicity of the PCL nanofibers and creeps slowly over the surface of nanofibrils due to gravity. The drop-casting was repeated on the scaffolds with type i, type ii and type iii fibers ([Fig. 6](#f6){ref-type="fig"}) to determine the fiber diameter that results into an ideal scaffold forming a prolate spheroid shaped hydrogel cupula. Type iii fibers were determined to be too thin and formed a loose network that readily allows the hydrogel to pass through the canopy and reach thereason for the enhancement of sensitivity of the cupula-dressed hair cell sensor over the naked hair cell sensor is mainly due to a combination of fluid mechanics of the cupula-fluid interaction and the material properties of hydrogel-like material. The cross-sectional surface area exposed to flow is much higher in case of the cupula encapsulated sensor (which feature a maximum diameter of 1000 μm compared to 350 μm in case of the hair cell), leading to an enhanced drag force. At low Reynold's numbers, the enhancement of the drag force due to the presence of the prolate shaped cupula can be approximated using the following scaling factor

where *F* is the drag force, *H* is the height and *D* is the diameter of the structure. Calculating using the physical geometry of the


Introduction {#Sec1}
============

The use of medicines among old people is very common and rapidly increasing (Barat et al. [@CR2]; Crockett [@CR6]; Fimea [@CR10]). Medication has become commoner as the prevalence of diseases in old age has increased (Crimmins and Beltrán-Sánchez [@CR5]), and diseases are more often treated with medicines (Giron et al. [@CR13]).

The use of medicines differs between the oldest old and the youngest old (Gislason et al. [@CR14]; Wastesson et al. [@CR39]), between old men and old women (Bell et al. [@CR3]; Gislason et al. [@CR14]; Pokela et al. [@CR36]) and between those living in different types of housing (Johnell and Fastbom [@CR21]; Jyrkkä et al. [@CR22]; Linjakumpu et al. [@CR24]). Previous studies have also reported that old people at the end of life are frequent users ofmedicines from several ATC categories, i.e. polypharmacy, increased, a trend that has also been shown in previous studies (Hajjar et al. [@CR17]; Haider et al. [@CR16]; Hovstadius et al. [@CR20]). Our results highlight the need to monitor and reconsider the medication of the increasing number of community-dwelling old people, in order to reduce the risk of adverse effects related to inappropriate medication, particularly when life expectancy is limited (Lane et al. [@CR23]; Holmes et al. [@CR18]; Maddison et al. [@CR26]).

A few limitations need to be addressed concerning the data. It is likely that people in the survivors group in earlier years may be survivors or decedents in later years. As our research data did not allow to take this possible overlapping into account, this may potentially threaten the


of the fragments and of their CM with respect to the target nucleus respectively. In Eq. (\[tbk\]), we have assumed that the angular distribution of fragments is isotropic in the projectile rest frame; the expressions without making this assumption are given in Ref. [@Bau89]. The last factor in Eq. (\[tbk\]) is given by $$\begin{aligned}
 \label{ederiv}
\frac{\partial E_p}{\partial E_{tot}} & = & m_t \left [m_p + m_t - m_p
                     \frac{{\bf p}_p \cdot ({\bf P} - {\bf p}_c)}
                     {p_{p}^{2}} \right ]^{-1},\end{aligned}$$ and the Jacobian $J^\prime$ is defined as $$\begin{aligned}
 \label{jacob}
J^\prime & =them offers unlimited access to all the new movies and current shows you want to watch.

The CBS All Access service, at $6 a month, debuted on Thursday. HBO has yet to announce pricing for its service, but some analysts have predicted it could cost roughly $10-$15 per month. Rivals Netflix, Amazon Prime, and Hulu currently charge about $8 per month (although the Amazon subscription includes free two-day shipping from the retail behemoth).

For new release movies and just-run television shows, you may also have to pony up to buy or rent them through Amazon, Apple TV or Google Play. The average basic cable subscription costs about $65. Your cable-free content bills will be less than that, but probably not by as much as you think.

3. There are still things


you can’t watch.

You won’t find the current season of cable hits like “Mad Men” or “Sons of Anarchy” available anywhere besides your cable television package. That can mean a year of missing out on post-show discussions and trying to avoid spoilers.

For sports fans, the availability of programming is pretty scarce, especially if you want to watch a live game on your ginormous-screen TV. Many of the sports leagues will let you watch a streaming game online for a fee, but only if that show is not being broadcast nationally or locally. (ESPN does have an app for digital viewing, but you need a cable log in to access it.)

4. You may still have to deal with your cable provider.

As much as you’d like to say goodbye forever tohad mvc version 5 but the new test project had a newer version.  All good now.
I didn't notice when I was using Nuget that the versions were different.
I think now is a good time for me to update all projects to the newest version of MVC.


You can view Bain's latest Global Private Equity Report here. The report below was published in February 2017.

Section 1. The private equity market in 2016: What happened?

Despite a slew of disruptive events that created volatile markets early in 2016, the private equity (PE) industry posted solid results for the year. With investors everywhere on the hunt for yield, private equity remains a favored asset for institutional investors who have the patience for longer-held bets. General partners (GPs) worked hard to keep their preferred status, finding and executing on good deals while rolling up their sleeves with portfolio companies to create value and successful exits.

Looking at the top-level metrics, the industry remained healthy in 2016, although some of the aggregate figures retreated from 2015 (see Figure 1.1). Exit activityasset. The greater the investor appetite for debt paper, the more willing lenders are to undertake transactions that can weaken a company’s balance sheet.

Therefore, dividend recaps are an option to achieve liquidity that is highly dependent on market conditions. In 2016, PE firms aggressively took advantage of periods of strong creditor demand outpacing supply to execute dividend recaps. The year started off slowly in this regard, with lenders being “risk off,” waiting for markets to stabilize for a sustained period before declaring “risk on” in the second quarter, when the market rebounded.

For the year through September 20, PE funds extracted $7.1 billion of dividends via the loan market, down 31% from the same period in 2015, according to Leveraged Commentary & Data (LCD). On deals for which LCD


raising more than $5 billion—as 11 megafunds closed to raise $90 billion (see Figure 1.9). Investors broadly do not cite megafunds as the most attractive type of fund, but such funds hold great appeal to large institutional investors who want to put a massive amount of capital to work in the asset class. And LPs who want to contain the complexity of their holdings see them as a way to limit the number of funds and relationships they need to track and manage.

Indeed, in 2016 many top-performing, large buyout firms returned to the market to raise capital—and with great success. Advent set out to raise $12 billion, attracted more than $20 billion of interest and settled on $13 billion. Thoma Bravo closed at $7.6 billion, reaching its hardcapital commitments. Some are raising ever-larger funds. Vista Equity Partners, for example, is raising $10.5 billion for its Fund VI, up from the almost $6 billion for Fund V, which it closed on in 2014. Others are raising additional capital outside their main buyout fund series, through funds with a different geographic focus or in other sub-asset classes such as infrastructure or direct lending. Traditional buyout firms closed on $85 billion in capital raised outside of their flagship buyout fund series in 2016, and this type of fund-raising has had a compound annual growth rate (CAGR) of 10% since 2013.

High-performing GPs have been taking advantage of sterling market conditions to negotiate more favorable terms with LPs. Some have broken convention for hurdle rate, the minimum rate of return


in the year, caused by factors ranging from China’s stock bubble burst to a drop in oil prices to uncertainty in Europe regarding Brexit, dampened buyouts. And persistently high asset prices throughout the year inhibited deal making.

In North America, buyout activity never fully recovered from a slow first quarter, with the 2016 deal count down 24% and value down by 16%.

Europe saw a milder contraction, with the deal count down only 11% and value dropping 10%, a trend caused mainly by steeper declines in the UK. Despite being whipsawed by economic and political events, investors in Europe quickly got back to business after each flare-up.

Looking at Asia-Pacific’s PE investments more broadly than buyouts, the count slid 14%, and value declined 26%. It’s important to note, though, that thesesovereign debt default to the surge of refugees crossing the Mediterranean, a steady barrage of headlines out of Europe for much of the past decade portrays a perpetually troubled region. The Brexit vote crystallizes growing popular frustration with the cumbersome governance structure within the European Union as well as the economic challenges resulting from structural weaknesses in the arrangement of the eurozone.

Some LPs increasingly voice doubts about the region. “Remind me again,” they ask, “why should I invest in Western Europe?”

On the surface, Europe does appear less attractive than the US, the main developed-market alternative in which to invest capital. Economic growth in the eurozone has lagged the US. Diverse languages and cultures make doing business across borders more difficult. Any comprehensive solution to the structural challenges of


UK and EU or the EU and US—affect the business? How does this investment affect the fund’s overall exposure to Europe? In which national reference currency would returns be measured and paid out?

If the macroeconomy continues to recover, how would that alter the target’s growth trajectory? Is there an opportunity to play the economic cycle? Will the underlying trends supporting unit volume growth prevail or even accelerate? Can pricing be used to create more value? Will the target’s competitive position get further entrenched? How would that affect deal economics?

No one knows whether the grand EU and eurozone experiments will endure another generation. But however they turn out, the region merits continued consideration. GPs who choose their investments carefully and manage currency exposure can thrive despite, or even becausebecause you did not crisply articulate your sweet spot or communicate it broadly enough?

Do you lack a relationship with the intermediary? If so, should you invest time to become acquainted because he or she will likely shop for more deals in your sweet spot?

If a deal made it into the pipeline and you rejected it, did the winning bidder spot something you missed? If so, which experts could augment your deal teams to better size up opportunities in the future?

There’s always an excuse to put off networking, unless it’s reinforced by the culture and compensation system. But with proprietary deals so hard to come by, expanding the circle of advisers and influencers, combined with a sharp point of view about what types of deals will make the best


Oglaigh Na hEireann says it intended to target Enniskillen hotel where world leaders will stay in June

This article is more than 7 years old

This article is more than 7 years old

The republican terror group Oglaigh Na hEireann has claimed that a car bomb abandoned in County Fermanagh at the weekend was to be detonated at the hotel hosting the G8 summit of world leaders in June.

In a coded statement to the Guardian on Monday afternoon, the anti-ceasefire republican dissident organisation also admitted responsibility for an attempted mortar bomb attack on the heavily fortified New Barnsley police station in west Belfast two weeks ago.

ONH also provided two photographs of a mortar launching device alongside a printed note stating: "MK1 10KG Mortar, Range 300 Metres."

The terror group's terse statement said:purged on save

# Jobs
JOB_THRESHOLD_DAYS = 90
JOB_FROM_EMAIL = 'jobs@python.org'

# Events
EVENTS_TO_EMAIL = 'events@python.org'

# Mail
DEFAULT_FROM_EMAIL = 'noreply@python.org'

### Pipeline

from .pipeline import PIPELINE

### contrib.messages

MESSAGE_TAGS = {
    constants.INFO: 'general',
}

### SecurityMiddleware

X_FRAME_OPTIONS = 'DENY'

### django-rest-framework

REST_FRAMEWORK = {
    'DEFAULT_AUTHENTICATION_CLASSES': (
        'rest_framework.authentication.TokenAuthentication',
    ),
    'DEFAULT_RENDERER_CLASSES': (
        'rest_framework.renderers.JSONRenderer',
    ),
    'URL_FIELD_NAME': 'resource_uri',
    'DEFAULT_FILTER_BACKENDS': (
        'django_filters.rest_framework.DjangoFilterBackend',
    ),
    'DEFAULT_THROTTLE_CLASSES': (
        'rest_framework.throttling.AnonRateThrottle',
        'rest_framework.throttling.UserRateThrottle',
    ),
    'DEFAULT_THROTTLE_RATES': {
        'anon': '100/day',


have not been pinned down exactly. While rigorous upper and lower bounds can be derived via the *first* and the *second moment method* [@ANP], these bounds do not quite match in most examples, including prominent ones such as random $k$-SAT or random graph $k$-coloring. In fact, the statistical mechanics techniques suggest a striking explanation for this discrepancy, namely the existence of a *condensation phase* shortly before the threshold for the existence of solutions. In this phase, a crucial necessary condition for the success of the (standard) second moment method is violated. Indeed, in statistical mechanics a deep formalism called *Survey Propagation* (‘SP’) has been developed expressly to deal with condensation. While SP is primarily an analysis technique, an off-spin has been the *SP guided decimation* algorithm, which seems highlyexponential in $n$. This “shattering” of ${\mathcal{S}}({\vec\Phi})$ was indeed established rigorously in [@Barriers].

As the density $r$ increases beyond ${r_{\mathrm{sh}}}$, both the overall number $Z({\vec\Phi})$ of solutions and the number and sizes of the clusters shrink. However, the cluster sizes decrease at a slower rate than $Z({\vec\Phi})$, until at density ${r_{\mathrm{cond}}}=2^{k-1}\ln2-\ln2+o_k(1)$ the largest cluster has size $\Omega(Z({\vec\Phi}))$ [w.h.p.]{}In effect, in the *condensation phase* ${r_{\mathrm{cond}}}<r<{r_{k\mathrm{-NAE}}}$, the set ${\mathcal{S}}({\vec\Phi})$ still decomposes into an exponential number of clusters $S_1,\ldots,S_{N({\vec\Phi})}$, each of tiny diameter and all mutually separated by Hamming distance $\Omega(n)$. But in contrast to the shattered phase, now the largest cluster contains a *constant* fraction of the entire set ${\mathcal{S}}({\vec\Phi})$. Indeed, [w.h.p.]{} a *bounded* number of clusters contain a $1-o(1)$-fraction of all solutions.

The dominance of a few large clusters in the condensation phase


rigidity emerges from the “global” interplay of variables and clauses. In effect, parametrizing by the number of rigid variables appears technically infeasible.

Instead, we are going to work with a simple “local” parameter that turns out to be a good substitute. Suppose that $x\in\cR(\sigma)$. Then $x$ must occur in some clause ${\vec\Phi}_i$ that would be violated if $x$ was assigned the opposite value $1-\sigma(x)$ (with all other variables unchanged). By the definition of $k$-NAESAT, this means that the other $k-1$ literals of ${\vec\Phi}_i$ take the opposite value of the literal whose underlying variable $x$ is. In this case we say that $x$ *supports* ${\vec\Phi}_i$ under $\sigma$, and we call ${\vec\Phi}_i$ a *critical* clause. Moreover, we call a variable that supports a clause *blocked*, while all other variables are *free*.of [Theorem]{} \[Thm\_NAE\] (lower bound).*]{} By [Corollary]{} \[Cor\_centreTerms\] and the Paley-Zygmund inequality, for any $r<r^*$ for a random $\vec d$ chosen from the distribution $\vec D$ we have [w.h.p.]{} $$\label{eqlowerboundfinal1}
    {\mathrm{P}}{\left\lbrack{{{\vec\Phi}_{\vec d}}\mbox{ has an NAE-solution}}\right\rbrack}\geq{\mathrm{P}}{\left\lbrack{{\mathcal{Z}}_\beta>0}\right\rbrack}\geq1/C.$$ Since $\vec D$ is precisely the distribution of the degree sequence of the uniformly random formula ${\vec\Phi}$, we have $${\mathrm{E}}_{\vec d}{\left\lbrack{{\mathrm{P}}{\left\lbrack{{{\vec\Phi}_{\vec d}}\mbox{ has an NAE-solution}}\right\rbrack}}\right\rbrack}={\mathrm{P}}{\left\lbrack{{\vec\Phi}\mbox{ has an NAE-solution}}\right\rbrack},$$ where the expectation on the left hand side ranges over $\vec d$ chosen from $\vec D$. Therefore, (\[eqlowerboundfinal1\]) implies that $$\label{eqlowerboundfinal2}
    {\mathrm{P}}{\left\lbrack{{\vec\Phi}\mbox{ has an NAE-solution}}\right\rbrack}\geq\frac1C-o(1),$$ which remains bounded away from $0$ as $n{\rightarrow}\infty$. Hence, (\[eqlowerboundfinal2\]) implies that ${r_{k\mathrm{-NAE}}}\geq r^*$, as the $k$-NAESAT threshold is sharp.

Proof of [Proposition]{} \[Prop\_realFirst\] {#Sec_realFirst}
--------------------------------------------

We begin with the following simple observation.

\[Lemma\_NAEsolution\] For any $\vec d$ and any $\sigma{\left\{{0,1}\right\}}^V$


   \end{aligned}$$ Indeed, the factor $k^{2|S|}$ accounts for the number of ways to choose the two relevant clauses supported by each variable, and the second factor bounds the probability that each of these clauses contains another occurrence of a variable from $S$. Now, (\[eqdegs\]) yields $$\begin{aligned}
    {\mathrm{P}}_{{{\vec\Phi}_{\vec d}}}{\left\lbrack{{\mathcal{D}}(S)}\right\rbrack}&\leq&{{\left({\frac{2k^2|S|\ln(n/|S|)}{n}}\right)}}^{2|S|}.
    \end{aligned}$$ For $0<s\leq 1/k^5$ let $X_s$ be the number of sets $S$ of size $|S|=sn$ for which ${\mathcal{D}}(S)$ occurs. Then $$\begin{aligned}
    {\mathrm{E}}{\left\lbrack{X_s}\right\rbrack}&\leq&{{{n}\choose {sn}}}{\left\lbrack{2k^2s\ln(1/s)}\right\rbrack}^{2sn}
        \leq{\left\lbrack{\frac{{\mathrm{e}}}s\cdot{\left({2k^2s\ln(1/s)}\right)}^2}\right\rbrack}^{sn}
            \leq{\left({4{\mathrm{e}}k^4 s\ln^2(1/s) }\right)}^{sn}=o(1).
    \end{aligned}$$ Summing over all possible $s$ and using Markov’s inequality completes the proof.

\[Lem\_supporting\] The expected number of solutions $\sigma\in{\mathcal{S}}({\vec\Phi})$ in whichis $k / (2^{k-1}-1)$. Moreover, the events that different clauses are critical are independent, implying that $C$ is distributed like ${{\rm Bin}}(m, k/(2^{k-1}-1))$.

Note that $
    {{\mathrm{E}}}[C ~|~ {\mathbf 1} \in {\cal S}(\Phi_{\mathbf{d}})] = m \cdot {k}/({2^{k-1}-1}) = \lambda n
$. By applying Lemma \[lem:locallimit\] with $\delta = 0$ we thus obtain that $$\Pr[C = \lambda n ~|~ {\mathbf 1} \in {\cal S}(\Phi_{\mathbf{d}})] = \Theta(n^{-1/2}).$$ It follows that the probability in  equals $$\label{eq:condoncriticalclauses}
    \Theta(n^{-1/2}) \cdot \Pr[{\mathbf 1} \text{ is $\beta$-heavy and no variable supports $\ge 3k$ clauses} ~|~ C = \lambda n \text{ and } {\mathbf 1} \in {\cal S}(\Phi_{\mathbf{d}})].$$ In the sequel we adopt a different formulation of this probabilistic question that is based on the classical occupancy problem. Let us think of the


} {\cal B}\right]
    \ge \Pr[{{\rm Bin}}(n, e^{-\lambda}) = (1 - \beta)e^{-\lambda}n] \cdot e^{-O_k(k4^{-k})},$$ and the proof of the proposition is completed after applying Lemma \[lem:auxf\].

In the remainder of the proof we will write $\mathcal{D}_i$ for the set of bins with capacity $i$ and $\mathcal{D}^{\ge \alpha}$ for the set of bins with capacity smaller than $kr - \alpha\sqrt{kr}$ or larger than $kr + \alpha\sqrt{kr}$, and note that $|\mathcal{D}_i| = D_i$ and $|\mathcal{D}^{\ge \alpha}| = D^{\ge \alpha}$.

 \
*Proof of .* Since $T$ is distributed like ${{\rm Bin}}(krn, \lambda/kr)$ we have that ${{\mathrm{E}}}[T] = \lambda n$. The result then follows by applying Lemma \[lem:locallimit\] with $\delta = 0$ to $T$.

 \
*Proof of .* Recall that the number of bins with capacity $i$ is denoted by $D_i$. Since the number of balls in alater age of about 52 years.

Data from the Northern Ireland Neuroendocrine Database ([Table I](#tbl1){ref-type="table"}) includes 517 carcinoid tumours of the appendix, midgut and lung diagnosed since 1975. 114 of these were appendiceal carcinoids, 16 of which were goblet cell in nature. The age at diagnosis and the presence of metastatic disease is shown in the table below. The mean age at diagnosis was 54.75 years ±4.57 SEM. Four of the 16 patients have since died. The only patient with hepatic metastases died from recurrent goblet cell carcinoid tumour, ten years following her appendicectomy and subsequent right hemicolectomy.

######

Patients diagnosed with appendiceal carcinoid from the Northern Ireland Neuroendocrine Database

  Patient   Age at Diagnosis   Metastases
  --------- ------------------ -------------------
  1


 Yes - hepatic
  15        43                 No
  16        70                 No

MALIGNANT CHANGE
================

Tumour characteristics of all appendiceal carcinoids that predict aggressive behaviour include tumour size, histological subtype and mesoappendiceal involvement. Moertel *et al*[@b5] first indicated in 1968 that metastatic disease from lesions smaller than 2cm was unlikely and consequently considered that the risk of metastatic disease in tumours less than 2 cm was sufficiently low to treat them by appendicectomy alone. In one study mesoappendiceal extension correlated with nodal metastases and tumourno future problem from the lesion. Patients with goblet cell carcinoid tumours however fall into a different category, as these tumours are more aggressive than classic appendiceal carcinoids. They are characterized histologically by wide invasion of the mesoappendix, and clinically by delayed local recurrence and distant metastases. As the vast majority of these tumours are detected post-operatively, management centres on the need for re-operation as a right hemicolectomy is often curative.[@b12] In patients with goblet cell carcinoids relative indications that may favour further surgery are: (1) angioinvasion as an isolated finding, (2) tumours at the base of the appendix with clear margins, greater than 1cm but less than 2cm in diameter and (3) mucin-producing tumours.[@b13]

CONCLUSIONS
===========

When considering appendiceal carcinoids as a whole, acceptable indications for a right hemicolectomy are


&tag, uint32_t start, uint32_t end) const;
  /**
   * \brief Returns an iterator over the set of byte tags included in this packet
   *
   * \returns an iterator over the set of byte tags included in this packet.
   */
  ByteTagIterator GetByteTagIterator (void) const;
  /**
   * \brief Finds the first tag matching the parameter Tag type
   *
   * \param tag the byte tag type to search in this packet
   * \returns true if the requested tag type was found, false otherwise.
   *
   * If the requested tag type is found, it is copied in the user's
   * provided tag instance.
   */
 bool FindFirstMatchingByteTag (Tag &tag) const;

  /**
   * \brief Remove all byte tags stored in this packet.
   */
  void RemoveAllByteTags (void);

  /**
   * \param os output stream in which the data should be printed.
   *
   * \brief Iterate over the byte tags present in this packet, and
   * invoke the Print method of each tag stored in the packet.
   */
  void PrintByteTags (std::ostream &os) const;

  /**
   * \brief Add a packet tag.
   *
   * \param tag the packet tag type to add.
   *
   * Note that this method is const, that is, it does not
   * modify the


(Unit* Left = Unit::GetUnit(*me, LeftHead))
        {
            iaggro = rand() % 3;

            DoScriptText(GoCombat[iaggro].id, Left);

            Delay_Timer = 3500;
            AggroYell = true;
        }

        if (pInstance)
            pInstance->SetData(TYPE_WARBRINGER, IN_PROGRESS);
    }

    void JustSummoned(Creature* summoned)
    {
        if (summoned->GetEntry() == ENTRY_LEFT_HEAD)
   ThreatDelay1[ithreat].creature ? Left : Right);

                DoScriptText(ThreatDelay1[ithreat].id, source);
                ThreatYell = false;
                ThreatYell2 = true;
            }

            if (KillingYell)
            {
                Unit* source = (Left->GetEntry() == KillingDelay[ikilling].creature ? Left : Right);


            me->AddThreat(pTarget, 0.0f);
            }
            ResetThreat_Timer = 35000 + rand() % 10000;
        }
        else ResetThreat_Timer -= diff;

        if (Fear_Timer <= diff)
        {
            DoCast(me, SPELL_FEAR);
            Fear_Timer = 15000 + rand() % 25000;
        }
       And then in Week 5 when I ran for 20 minutes straight, I cried tears of joy because it seemed like something that would never be possible!

There I was just a few short years ago thinking 5 miles was crazy, that a hike would wipe me out for days, that running 20 minutes non-stop took superhuman effort. And now? Now a lot of those things are what I consider "easy". I run five miles ON A TUESDAY without barely even a blink. I don't just hike that North Hills trail, I freaking RUN parts of it. And soreness afterwards? Barely even noticeable. I don't just run 20 minutes, I can run for hours.

It just shows to go ya that we can achieve a lot when we put our


whatsoever. My boss in on the Board, so we pulled together a small team of about 5 employees to participate in the 5k. Since I knew I had 12 on the plan, I did consider running the half, but it was $90 (!!!) and I wasn't going to pay that to run in Menifee...not scenic at all, mostly along city streets, so small the course support was minimal, and there were no cheering sections...in my opinion, that price point is WAY too high and they would do a lot for themselves if they lowered it to about $50 until they grow it a little bit.)

I headed out at what should have been a manageable pace but my body just wasn't cooperating in the slightest. I ended up walkingand one of the toenails has already bitten the dust! But it is what it is...we'll see how many more join that one along the course, eh?

Week 4:
Easy 3 miles - Fail...didn't do one at all, but I did do a considerable amount of walking at Disneyland with the kiddos! That counts, right? hahaha
Easy 5 miles - Again, fail...didn't even try. I was wiped. I had a blister. The excuses could continue.
Tempo for 3x1 mile - Only managed to do 2 of the 3 repeats, but nailed the pace on the two that got done. I can tell I am going to have a hard time fitting these higher mileage days in during the workweek...but I'll keep trying!Easy 3 miles - TBDLong Run 12 miles with 6 at


In one of our previous posts about creating Helm Charts for Kubernetes, we outlined what we consider the best practices for creating Helm charts. We’ve been using Helm in production and investing our time in creating Helm charts (available on the Banzai Cloud Charts GitHub repository) since Banzai Cloud’s inception. Creating Helm Charts is one thing; storing and serving them is another. We’d like to reduce the burden this places on the user, so today marks the launch of our Helm Chart repository service, which you can use to store and serve public Helm Charts for free.

Our Helm Chart service is based on ChartMuseum, an open-source, easy to deploy, Helm Chart repository server. We are using the upstream ChartMuseum distribution without any modifications. We have, however, added certainIntroduction {#Sec1}
============

The decidua is a transient but important platform in the uterine tissue, which comprises terminally differentiated endometrial stromal cells, newly generated maternal vascular cells, and maternal blood cells inside and outside the vessels. Development of the decidua after attachment of the blastocyst on uterine wall is a drastic tissue remodeling, involving physical and humoral changes in the residential and recruited immune cells. Indispensability of the decidual tissue for establishing implantation of the embryo and maintaining pregnancy until the stage of placenta formation was first indicated by its physical importance when mice were challenged by blastocyst transfer into the peritoneal cavity and failed \[[@CR1]\], and when tubal decidual formation was observed in some cases of human ectopic implantation in the ovary or peritoneal cavity \[[@CR2]\], and when embryonic


diseases, ovarian functions and other endocrinal system are also affected. Typical remedy with combination of IVIg and NSAIDs may just suppress cytokine storms, but without understanding the basis it is hard to select appropriate patients.

Better understanding the mechanisms via optimal animal models {#Sec16}
-------------------------------------------------------------

A number of molecules, e.g., leukemia inhibitory factor (LIF) and lipid mediator prostaglandins, associated with "uterine receptivity" have been identified in PR and ER pathways and Wnt signaling, via gene-deficient murine models \[[@CR18]\]. Immunologists in the field of reproduction have utilized T, B, NK-deficient Rag2^−/−^Δγc or T, NK-deficient tgε26 to elucidate the role of immune cells in decidual vascular remodeling failure. However, these immunodeficient mice did not show complete pregnancy loss, with only modest changes in uterine vascular remodeling or decidual cellularity, let alone the highrepos and issues for LWC, we have found the solution on the bottom readme of the LWC Recipes OSS repo:
The Edge browser currently doesn't support native shadow DOM. If you want to use this application you have to manually add the synthetic shadow DOM to your clone. Add to the first line of the index.js this code:

import '@lwc/synthetic-shadow';

So, we modified the main index.js file to add the import on the first line and now it works:
import '@lwc/synthetic-shadow';
import { buildCustomElementConstructor } from 'lwc';
import MyApp from 'my/app';

customElements.define('my-app', buildCustomElementConstructor(MyApp));


will it fit?

SunGrow Dog and Cat Car Seat Belt is adjustable, accommodating both large and small sized pets. Ranging from 19” to 31” (48cm - 79cm) in length, the belt can be tightened for a small breed pets like a beagle for a dog, and munchkin for a cat. It can also be easily extended to a length more suitable for larger pets such as golden retriever or maine coon. The convenient adjustable length gives you the freedom to determine how much your pet can move about.

What is the SunGrow Dog and Cat Car Seat Belt made out of?

Designed and constructed with the safety of your pet in mind, this highly reliable seat belt is made with incredibly strong nylon fabric so that you can confidently and safelybring along your cherished family pet. Whether you’re taking a short car-trip to the pet store or a two week family vacation in the mountains, the sturdy and safe Car Seat Belt for Dogs and Cats helps protect your pet from unexpected accidents while on the road.

How do I use this seat belt for Dogs and Cats?

One end of the belt has a simple universal clip that securely attaches to your pet’s body harness while the other end has a standard seat belt buckle that inserts into your vehicle’s seat belt receptacle. For your pet’s safety, do not attach the SunGrow Dog and Cat Car Seat Belt to your pet’s collar; attach it to a comfortable body harness. By connecting your pet to a body harness instead of


var unique = {},
        distinct = [];
    for (var i in staff) {
        if (typeof (unique[staff[i].id]) == "undefined")  {
            distinct.push(staff[i].id);
        }
        unique[staff[i].id] = unique[staff[i].id] || {pay:0};
        unique[staff[i].id].name = staff[i].name;
        unique[staff[i].id].pay += (parseInt(staff[i].rate, 10) * parseInt(staff[i].hours, 10));
    }

    var pay = [];
    for (var p in unique) {
        pay.push([p, unique[p]]);
       pay.sort(function (a, b) {
            return (b[1].pay - a[1].pay);
        });
    }

    var staffService = {};
    staffService.allStaff = function () {
        return staff;
    };

    staffService.CalcPay = function () {
        return pay;
    };

    return staffService;
});

app.controller('MainCtrl', ['$scope', 'staffFactory', function ($scope, staffFactory) {
    $scope.staff = staffFactory.allStaff();
    $scope.CalcPay = staffFactory.CalcPay();
    $scope.keyPress = function(keyCode){
        console.log($scope.staff);
        $scope.CalcPay = staffFactory.CalcPay();


Even though these two terminals receive the same transmitting data rates, the terminal having 7 dB for C/I evidently have lower error rate of transmitted packets than the other with 4 dB. Consequently regardless of equal transmitting data rates, the scheduler must allocate more time slots to the terminal having higher values of C/I in order to increase the system throughput efficiency. Since the PF scheduler gives the equal priorities on the terminals having same transmitting data rates, it makes a worse as far as the system throughput efficiency is concerned
Furthermore the PF scheduler is not able to prioritize the individual terminal grade and provided service type at all. For instance, it is desirable for a terminal requiring real-time services, such as image data, to have a higherand the legitimacy of same-sex orientation is that of “epiphany”: once God appeared to his disciples, surprising them, and he now manifests himself afresh. The epiphany Mitchell presents is that the church should, because of “a divine wind,” as he calls it, embrace same-sex orientation.

Mitchell’s rhetoric reaches fresh heights of self-congratulation: “One day I will write a memoir, and a large portion of that memoir will be about this life-giving experience. The book is not to be written yet, because the final chapters are yet unwritten.” He speaks to the difficulty of the issue at hand: “I have been broken almost to the point where I despaired of life, but I have been encouraged.” Finally, he compares the struggle before him to the civil rights cause: “Could you


The pot it came in was tall and narrow, but I'm not sure that's a good idea if it has no roots. How can I properly rehabilitate this orchid?
Here's what it looks like now:

A:

It appears you have a specimen of Phalaenopsis sp. also known as moth orchid.
Your particular specimen, judging by the photo included in your question, has strong new root growth. This is encouraging - you have been doing something right.
From Wikipedia...

Phalaenopsis are among the most popular orchids sold as potted plants,
owing to the ease of propagation and flowering under artificial
conditions.

In nature, Phalaenopsis thrive in temperatures around 20 to 35 °C (68 to 95 °F), but are adaptable to conditions more comfortable for human habitation in temperate zones 15 to 30 °C (59 to 86 °F). NoteMariano Barreto

Mariano Barreto (born 18 January 1957) is a Portuguese football manager who coaches Stumbras in Lithuania.

Coaching career
In January 2009, he became an assistant coach in the Russian Premier League with FC Kuban Krasnodar. Barreto was officially registered as head coach of Kuban because Sergei Ovchinnikov, who really managed the team, did not own a UEFA Pro Licence.

In April 2014, Barreto was selected to take over the head coach of Ethiopia. He agreed to leave the position on 18 April 2015.

From 2016 manager in FC Stumbras. In 2017 won Lithuanian Football Cup.

Honours
Individual
 A Lyga Coach of the Month: June & July 2018

References

Category:Portuguese football managers
Category:Portuguese expatriate football managers
Category:Portuguese expatriate sportspeople in Lithuania
Category:Ghana national football team managers
Category:Ethiopia national football team managers
Category:C.S. Marítimo managers
Category:AEL Limassol managers
Category:Indian Roman Catholics
Category:Portuguese Roman Catholics
Category:Associação Naval


bring you news therefrom, or a torch to warm you." 8. When he came to it, he was called: "Blessed is the One (who is speaking from) within the fire, and those around it." Glory be to GOD, Lord of the universe. 9. "O Moses, this is Me, GOD, the Almighty, Most Wise. 10. "Throw down your staff." When he saw it moving like a demon, he turned around and fled. "O Moses, do not be afraid. My messengers shall not fear. 11. "Except those who commit a transgression, then substitute righteousness after sinning; I am Forgiving, Most Merciful. 12. "Put your hand in your pocket; it will come out white, without a blemish. These are among nine miracles to Pharaoh and his people, for they are wicked35. "I am sending a gift to them; let us see what the messengers come back with." 36. When the hoopoe returned to Solomon (he told him the news), and he responded (to Sheba's people): "Are you giving me money? What GOD has given me is far better than what He has given you. You are the ones to rejoice in such gifts." 37. (To the hoopoe, he said,) "Go back to them (and let them know that) we will come to them with forces they cannot imagine. We will evict them, humiliated and debased." 4

7 CENTER = Faster Than the Speed of Light 38. He said, "O you elders, which of you can bring me her mansion, before they arrive here as submitters?" 39. One afrit from


the jinns said, "I can bring it to you before you stand up. I am powerful enough to do this." 40. The one who possessed knowledge from the book said, "I can bring it to you in the blink of your eye." When he saw it settled in front of him, he said, "This is a blessing from my Lord, whereby He tests me, to show whether I am appreciative or unappreciative. Whoever is appreciative is appreciative for his own good, and if one turns unappreciative, then my Lord is in no need for him, Most Honorable." 41. He said, "Remodel her mansion for her. Let us see if she will be guided, or continue with the misguided." 42. When she arrived, she was asked, "Does your mansionon it mountains, and created a barrier between the two waters? Is it another god with GOD? Indeed, most of them do not know. 62. Who is the One who rescues those who become desperate and call upon Him, relieves adversity, and makes you inheritors of the earth? Is it another god with GOD? Rarely do you take heed. 63. Who is the One who guides you in the darkness of land and sea? Who is the One who sends the winds with good news, signaling His mercy? Is it another god with GOD? Most exalted is GOD, above having any partner. 64. Who is the One who initiates the creation, then repeats it? Who is the One who provides for you from the heaven and the earth?


You are here

Girls set to Rock London

In preparation for their participation in the FIRA-AER Sevens 2014 Championship in Bergen, Norway on 7 and 8 June, Scotland Women 7s – playing as Scotland Select – will be taking part in Rugby Rocks at Richmond Athletic Ground in London tomorrow (31 May).

Coached for the third season by former Scotland 7s captain, Scott Forrest, an extended squad have been together for two training camps. The team comprises experienced Scotland Women players, including winger Sarah Dixon and full back Steph Johnston, alongside relative newcomers to the game such as Rose Anderson, a former Olympic basketball player!

The team for Bergen – where Scotland are pooled with Moldova, Croatia and Finland – will be announced on Wednesday 4 June. Twelve teams compete in threePat.
*[[Georgie]] - Killed for trying to protect Pat.
*[[Vinnie]] - Killed for betraying him.
===Other Murders===
*[[Freddy (GTA A)|Freddy]] - If Mike waits, Freddy betrays Mike and sends his associates to kill him, but Mike kills all the associates and kills Freddy too.
*[[Biff Rock]] - If the player chooses to.
===Trivia===
Mike's has green pants and a gra/black shirt because grand theft auto advance was supposed to be a port for grand theft auto 3
{{GTA Advance Characters}}
[[nl:Mike (GTA Advance)]]
[[Category: Characters|Mike]]
[[Category: Characters in GTA Advance|Mike]]
[[Category: Protagonists|Mike]]

Mike is the protagonist in Grand Theft Auto Advance. Along with his associate Vinnie, the two had earned enough money to leave Liberty City for good, but Mike was coaxed by Vinnie to take a few more jobs from the Mafia before leaving. After Vinnie was thought to be


Q:

Yeoman's Angular.js codelab - fixing the tests

I complete the tutorial from this codelab, and as suggested tried to fix the errors on the unit tests.
But i don't know how to fix this error. I already took a look at this question:running-tests-with-localstorage but it does not address my problem.
Here's my test file:
'use strict';

describe('Controller: MainCtrl', function () {

  // load the controller's module
  beforeEach(function(){
    module('mytodoApp'),
    module('LocalStorageModule')
  });

  var MainCtrl,
    scope;

  // Initialize the controller and a mock scope
  beforeEach(inject(function ($controller, $rootScope) {
    scope = $rootScope.$new();
    MainCtrl = $controller('MainCtrl', {
      $scope: scope
    });
  }));

  it('should have no items to start',show that this emerging class of quantum materials can be harnessed to fill a long known gap in the field of mid-infrared lasers and photonics.

Results
=======

Cd~3~As~2~ film growth and characterization
-------------------------------------------

We first prepared high-quality Cd~3~As~2~ films under ultra-high vacuum in MBE system (see Methods section). The thickness of the film was *in situ* monitored by reflection high-energy electron diffraction (RHEED). As shown in [Fig. 1](#f1){ref-type="fig"} inset, a typical RHEED pattern of Cd~3~As~2~ films shows bright and streaky lines, indicating a good surface morphology and crystallinity. X-ray diffraction measurements were also performed ([Fig. 1](#f1){ref-type="fig"}). A series of peaks can be well resolved and indexed as {112} crystal plane (the un-indexed peaks come from the mica substrate), further confirming the good crystallinity of the sample[@b33]. Magneto-transport measurements on the Cd~3~As~2~ films were


conducted using a physical property measurement system with a superconducting magnet (9 T). The Shubnikov--de Haas oscillations, non-trivial Berry phase and vanishingly small effective mass confirmed the Dirac nature of Cd~3~As~2~ thin film (see [Supplementary Fig. 1](#S1){ref-type="supplementary-material"}). Hall measurements revealed an electron mobility of ∼3,300 cm^2^ V^−1^ s^−1^ at room temperature and 5,400 cm^2^ V^−1^ s^−1^ at low temperature (2.5 K).

Ultrafast nonlinear optical spectroscopy
----------------------------------------

Photoexcitation and carrier relaxation are fundamental processes that govern the optical response of materials. For Cd~3~As~2~, an optical conductivity over broad mid-infrared wavelengths that is linked to the intrinsic Dirac band dispersion provides an important prerequisite for robust and tuneable light--matter interactions[@b34]. To investigate the ultrafast optical switching characteristics of Cd~3~As~2~, mid-infrared ultrafast pump-probe spectroscopy is performed (see Methods section). It should be noted that, while degenerate probing is known to better approximatedown from 4 to 9.3 ps as the probe wavelength was increased to ∼6 μm. It should be noted that these time constants are appreciably longer than two-dimensional Dirac fermions in graphene. As theoretical investigations reveal that carrier--acoustic phonon scattering occurs on the microsecond timescale[@b39], it is reasonable to attribute the primary relaxation process to optical phonon coupling, and the increase of the recovery time can be accounted for by the reduced optical phonon energy in Cd~3~As~2~ (∼15 meV) with respect to graphene (162--198 meV)[@b36][@b40]. In brief, these experimental results unambiguously confirm that MBE-grown Cd~3~As~2~ thin films exhibit ultrafast saturable absorption over broad mid-infrared wavelengths from 3 to 6 μm.

To directly reveal the saturable absorption properties of Cd~3~As~2~, we further performed a nonlinear absorption measurement at a wavelength of 3 μm with an optical


parametric amplifier (OPA) delivering ∼100 fs pulses. [Figure 2c](#f2){ref-type="fig"} shows the power-dependent transmittance of Cd~3~As~2~. A rollover typically seen in saturable absorbers at high intensity irradiation is observed at fluences exceeding 7 GW cm^−2^ and the sample is found substantially damaged at a fluence of ∼12 GW cm^−2^ (ref. [@b41]). The measurement data can be fitted by a simple saturation model[@b42], *T*(*I*)=1−Δ*T* × exp(−*I*/*I*~sat~)−*T*~ns~, where *I*, Δ*T*, *I*~sat~ and *T*~ns~ are the input intensity, modulation depth, saturation intensity and non-saturable absorbance, respectively. This yields a modulation depth of ∼4.4% and a saturation intensity of ∼0.78 GW cm^−2^. At a wavelength of 2 μm, we obtain a modulation depth of ∼3.4%, a saturation intensity of ∼0.25 GW cm^−2^ and a damage threshold of ∼10 GW cm^−2^ with ∼100 fs pulse irradiation ([Supplementary Fig. 4a](#S1){ref-type="supplementary-material"}). Similar figures of merit were obtained by usingby means of a scalar theory, as commonly used. Here, we use the analytical solution of the scalar radiative transfer equation. With this evaluation approach, which does not consider polarization, we found large errors in [Formula: see text] and μa in the range of 25% and above. Furthermore, we investigated the applicability of the use of a reference measurement to reduce these errors as suggested in literature. We found that this method is not able to generally improve the accuracy of measurements in the spatial frequency domain. Our general recommendation is to apply a polarized theory when using crossed polarizers.


               let field = {'word': function_name . '(', 'abbr': description, 'kind': 'f', 'dup': 1} " always duplicate functions
                call complete_add(field)
            endif
        endfor
        return []
endfunction

" Find local function names {{{2
function s:erlangFindLocalFunc(base)
	" begin at line 1
	let lnum = s:erlangFindNextNonBlank(1)
	if "" == a:base
		let base = '\w' " used to match against word symbol
	else
		let base = a:base
	endif
	while 0 != lnum && !complete_check()
		let line = getline(lnum)
		let function_name = matchstr(line, '^' . base . '[0-9A-Za-z_-]\+(\@=')
		if function_name != ""
			call complete_add(function_name)
		endif
		let lnumin ever-growing numbers, fleeing a wave of anti-Semitism. Nidra Poller , American ex-pat writer and translator in Paris, has written some appalling stories about aggressive anti-Semitism, such as the murder and brutal torture of French Jew Ilan Halimi early in 2006.

Muslim blogs are calling for violence against the Jews, the whites and the well-to-do. They say, “We must burn France, as Hamas will burn Israel.” The growth of the Islamic population is explosive. According to some, one out of three babies born in France is now a Muslim. Around 70% of French prisoners are Muslims. Hundreds of Muslim ghettos are already de facto following sharia, not French law. Some have pointed out that the French military are not always squeamish, but there are estimates that 15% of the


in France.

Reconquista – The Second Expulsion of the Moors

Muslims strike too early, before they are ready to seize control over major chunks of Europe. They overestimate their own power, and underestimate the strength that is still left in Europe. It will start, as these things always do, before anyone is ready. Everyone, the Islamists, the proto-dhimmis, the neo-nationalists, the sleepwalking middle class, thinks they have more time than they do. It may start more or less by accident, like WWI, through the act of a fringe player unaware of the forces involved or the stakes of the game. Once a full-blown civil war starts in one country, it can, and probably will, spread to other countries. Given the European Union’s borderless nature, it is unlikely that war willand business within a decade or two. Instead of changing batteries once a year, you might change a pack of solutions every few months.

But detection has limited value if the system can’t respond to carefully identified threats. And key elements of our responsiveness are atrophying.

Fewer vaccines and antibiotics are being made as companies focus on higher-margin medicines. Pharmaceutical manufacturing requires specialized facilities that are not widely distributed. Drug development invariably takes years. Should a truly novel pathogen appear—due to bioterror, bio error, or a natural run of bad luck in a world that can produce things like Ebola by chance—a defense centered on stockpiles could be swiftly outmaneuvered.

It’s time to rearchitect our defenses by leveraging the very force of proliferation that threatens to destabilize the system. Rather than


tiny biochips, which print nucleic acids and then deliver them into our bodies. Imagine a dermal patch that integrates these chips with nanoneedles, which inject their output into the skin’s epithelial cells. These cells could then churn out protein-based therapeutics targeting the latest biohazard.

Some well-targeted R&D muscle could make this sort of system attainable within a decade or two. Paired with a biosensor network of the sort that George Church described on Ars yesterday, it could supercharge global public health efforts, improve national biosecurity, and put the biopharmaceutical industry on a technical foundation better suited to address the demands and threats of the 21st century.

Andrew is the CEO of Humane Genomics, a seed stage company developing synthetic viruses targeting cancer. He is also a co-founder of the Genome5 best verizon smartphones that you will love to buy

Best verizon smartphones: If you’re interested in learning pretty much in detail about best VerizonSmartphones, then you have stepped into the right place.Do you want to save with a pay-as-you-go scheduling and planning, or do you want actually a cool and wise smartphone you will really love? You no longer have to make that choice. Now, some of Verizon’s best-selling phones and honorable mentions are listed below with your best budget friendly devices.

Motorola Moto E (2015)

If you confessed Moto G was affordable, then go and check out the Moto E. For well under $100 on Verizon’s prepaid network, you’ll be getting all of the prominent features, the device is definitely modest a perfect model for casual user. Just do


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Listen to the most important stories of the day.

Contact us at letters@time.com.products (Pathom-aree et al., [@B47]; Abdel-Mageed et al., [@B1]). With the breakthrough of technological barriers associated with deep sea actinobacteria isolation strategies, such as sample collection and cultivation under standard laboratory conditions, more and more deep sea actinobacteria and their natural products have been identified. Here we review the recent progress on deep sea actinomycetes and their metabolites from literature during year 2006--2016.

Deep sea environment and biodiversity {#s2}
=====================================

The vast oceans cover 70% of the world\'s surface, with 95% greater than 1,000 m deep. Deep sea environments are divided into the bathyal zone (depths between 200 and 2,000 m), the abyssal (depths between 2,000 and 6,000 m) and the hadal zone (depths below 6,000 m) (Harino et al., [@B19]). Below sea level pressure is increased by depth, thereby in


Nankai and Okinawa Troughs.

Novel actinomycete species {#s4}
==========================

Novel actinomycete species isolated from deep sea environment between 2006 and 2016, have yielded an impressive array of novel species with the highest number found at depths of abyssal zone and deeper. Different media has been used by researchers (Table [1](#T1){ref-type="table"}). It is worth to be noticed that long time culturing and low temperature were employed for some of the novel isolates (Table [1](#T1){ref-type="table"}). Only one novel *Microbacterium marinum* was obtained by pretreatment at 55°C, 6 min, others were from none heat pretreated samples (Table [1](#T1){ref-type="table"}). The novel deep sea actinomycete species including 21 species under 13 genera with the maximum number from *Microbacterium* (*n* = 4), followed by *Dermacoccus* (*n* = 3), *Streptomyces* (*n* = 3) and *Verrucosispora* (*n* = 2),     Raffinose-histidine agar with cycloheximide and nystatin                             28°C for 12 weeks   Pathom-aree et al., [@B46]

**SM1^\*^**: yeast nitrogen base (67.0 g; Difco) and casamino acids (100 mg; Difco) are added to a liter of distilled water and the solution sterilized using cellulose filters (0.20 mm) prior to the addition of sterilized dipotassium hydrogen phosphate (200 ml; 10%,w/v);100 ml of this basal medium was added to 900 ml of sterilized molten agar (1.5%,w/v) followed by filter ster l sed solutions of D (−) sorbitol (final concentration 1%,w/v); **YP agar^\*^** per liter distilled water: 5 g, yeast


20.0 g, KNO~3~ 1.0 g, NaCl 0.5 g, MgSO~4~ x 7 H~2~O 0.5 g, K~2~HPO~4~ 0.5 g, FeSO~4~ x 7 H~2~O 10.0 mg, Agar 15.0 g, Sea water 1.0 L, Adjust pH 7.4; **Oligotrophic- seawater medium^\*^:** Oligotrophic medium (seawater, 2.0% agar); **Modified HV medium^\*^**: humic acid 1.0 g, KCl 1.7 g, FeSO~4~. 7H~2~O 0.01 g, Na~2~HPO~4~ 0.5 g, MgSO~4~. 7H~2~O 0.5 g, CaCO~3~ 0.02 g, thiamine 0.5 mg, nicotinic acid 0.5 mg, pantothenic acid 0.5 mg, p-aminobenzoic acid 0.5 mg, riboflavin 0.5 mg, vitamin B6 0.5 mg, inositol 0.5 mg, biotin 0.25 mg, water 250 ml, seawater 750 ml, agar 18 g, pH 7.2; **Humic acid-vitamin agar**^\*^: Humic acid 2g, Asparagine 1 g, K~2~HPO~4~ 0.5 g, FeSO~4~ 7H~2~O 0.5 g, Agar 20 g, Sea-water 1000 ml, pH 7.0--7.4;as homoeologous genomes. Although bread wheat possesses three homoeologous genomes (termed A, B, and D), meiosis proceeds as if the organism is a diploid, in that pairing only occurs between homologous chromosomes from the same genome (\[[@B6]--[@B9]\] and references within). This strict pairing interaction between homologous chromosomes has previously been shown to be controlled by *pairing homoeologous* (*Ph*) loci \[[@B10], [@B11]\]. The most extensively studied of these loci is the *Ph1* locus located on the long arm of chromosome 5B. While the molecular mechanism by which the *Ph1* locus operates is still subject to intensive research, *Ph1* appears to indirectly promote homologous chromosome pairing by suppressing homoeologous chromosome interactions through regulation of the specificity of chromosome interactions at centromeric and telomeric regions \[[@B12], [@B13]\].

In *ph1* deletion mutants, the


showed that *Ta*PHS1 shared relatively high levels of sequence identity with its homologues in other species (*Sorghum bicolor*\[*Sb*PHS1\]---53.6%, *Zea mays* \[*Zm*PHS1\]---51.2%, *Oryza sativa* \[*Os*PHS1\]---41.4%, and *Arabidopsis thaliana* \[*At*PHS1-like\]---21.5%). We propose that there are four prominent regions within the PHS1 amino acid sequence that are well conserved ([Figure 1(a)](#fig1){ref-type="fig"}). While a portion of Region 2 (corresponding to amino acid positions 99--145 of *Ta*PHS1) was previously identified to contain two conserved domains \[[@B27]\], interspecies comparisons made in the current study suggest that this conserved region can now be extended by 11 amino acid residues toward the N-termini of PHS1 proteins in monocot species ([Figure 1(a)](#fig1){ref-type="fig"}, dashed line). In addition, there is a short region of oligopeptide repeats from position 242 to 265 \[YSGFPEGYSGFPEGYSGFPEGYSG\] unique to *Ta*PHS1 ([Figure 1(a)](#fig1){ref-type="fig"}, boxed feature).

Tostages of meiosis examined in Chinese Spring wild type (open bars). In the *ph1b* mutant (black bars), *TaPHS1* is upregulated between 1.5- and 2-fold across the time points analysed. Normalisation of the Q-PCR data was performed against three control genes (*actin*, *GAPdH,* and *cyclophilin*) as per Crismani et al. \[[@B48]\]. Data represent the means ± SE of three replicates. Units on the *y*-axis represent normalised mRNA transcript *μ*L^−1^.](IJPG2012-514398.004){#fig4}

![*Ta*PHS1 localisation during early meiosis in wild type bread wheat. (a) Telomere bouquet stage, (b) leptotene, (c) early zygotene, (d) zygotene, (e) late zygotene/pachytene transition, (f) pachytene, (g) diplotene. *Ta*PHS1 (green; left panel) localises to 4′-6-diamidino-2-phenylindole- (DAPI-) stained chromatin (blue) as diffuse tracts and/or punctated foci (as seen by viewing the merged + DAPI image). Middle panels show the *Ta*ASY1 signal (red), while


Repairing the annular ligament is not necessary in the operation of Mason type 2, 3 isolated radial head fractures if the lateral collateral ligament is intact: Minimum 5 years follow-up.
The repair of annular ligament after open reduction and internal fixation of radial head fracture could produce the irritation or crepitation during range of motion exercise. The purpose of this study is to evaluate the significance of unrepaired annular ligament during fixation of isolated radial head fractures. Retrospectively we reviewed the twenty-five patients who underwent surgical fixation with a plate for Mason type 2, 3 isolated radial head fracture without annular ligament repair. All the radial head fracture did not have the associated injuries which could cause the elbow instabilities. The average length of follow-up was 6.9 years. Theyou know, it takes forever to be a good stand-up. I think people get impatient.

You could win two tickets to see Kathleen Madigan Oct. 5 at this SheSays-sponsored event. Enter to win two tickets to see comedian Kathleen Madigan by filling out the attached form at the bottom of the story. Must be 18 & older.


Body Sport Training Ropes are strong to withstand the toughest workouts indoors and outdoors. The popularity of fitness training ropes has soared in recent years because they can increase one?s overall strength and endurance, work biceps, forearms, shoulders, back, wrists and hand/grip all with one...

Body Sport Training Ropes are strong to withstand the toughest workouts indoors and outdoors. The popularity of fitness training ropes has soared in recent years because they can increase one?s overall strength and endurance, work biceps, forearms, shoulders, back, wrists and hand/grip all with one simple piece of equipment. Available in diameters of 1.5" and 2" with lengths of 15', 30', 40' and 50?, all ropes are made of durable, super-strong poly-twine wrapped at the ends so they won?t fray.So.2d 829 (Miss. *1185 1994), cert. denied ___ U.S. ___, 115 S.Ct. 2279, 132 L.Ed.2d 282 (1995).
The issues not properly raised or preserved in the record are procedurally barred. Notwithstanding the procedural bar, alternatively and independently this Court has considered and addressed these issues and found them to be without merit. A thorough examination of all other issues properly raised by Williams indicate there is no merit to his contentions. This Court affirms Williams' sentence of death.

STATEMENT OF FACTS
The State's case in chief commenced with the testimony of L.H. Fountain which focused upon the unavailability of witnesses Ronnie Russell and Gregory Lynn Fountain who had previously testified in Williams' original 1983 trial. Russell's and Fountain's prior testimony was read to the jury.
Ronnie Russell, twenty-seven years of age, testified,


did not have to be instructed on the elements of capital murder, murder and kidnaping in this case, in order to make a finding beyond a reasonable doubt of the existence of this aggravating circumstance. Williams is not being charged in the resentencing hearing as he was in his first trial. In Conner v. State, the defendant, Conner, claimed that an instruction on a lesser-included offense of simple murder should have been given. Conner v. State, 632 So.2d 1239, 1255 (Miss. 1993), cert. denied, ___ U.S. ___, 115 S.Ct. 314, 130 L.Ed.2d 276 (1994). The jury instruction given informed the jury that it could find Conner guilty of capital murder only if it found Conner to be guilty beyond a reasonable doubt of every element of the capitalScoreboard Lounge in the truck; second, when she requested to go get her shoes and was not returned to the Lounge; third, because of her intoxicated condition; and fourth, when she was dragged or carried into the woods from the truck. Williams, 544 So.2d at 790. In other words, the sufficiency of the proof as to the kidnaping has already been decided and is not to be challenged de novo by Williams at a resentencing hearing. Equally problematic for Williams was Evans' testimony that he observed Williams tackle Pierce when she attempted to run away. Such action was more than sufficient for the jury to consider as proof of the underlying felony of kidnaping.
Even though Williams' own instructions contained the 5(d) felony aggravator, Williams failed at trial to


1228 (Miss. 1995); Foster v. State, 639 So.2d 1263 (Miss. 1994); Box v. State, 610 So.2d 1148 (Miss. 1992).
Our death penalty scheme is silent with respect to certain resentencing proceedings upon retrial, and this Court has not had the occasion to offer guidance. The case of State v. Biegenwald, 106 N.J. 13, 524 A.2d 130, 158-61 (1987), contains some ground rules applicable in the state of New Jersey. The Supreme Court of New Jersey opined that "[s]ince the retrial is limited to resentencing, the only admissible evidence is that relevant to the issue, namely, evidence of aggravating and mitigating factors. Retrial of issues relevant only to guilt is not permitted." Biegenwald, 524 A.2d at 160. That Court found that if both "the State and the defense were freeinstruction to be almost identical to the one approved by this Court in Conner. The only difference is that the Conner instruction inserts the phrase "where there is a dismemberment of the corpse" after "serious mutilation" in the third sentence. Conner, 632 So.2d at 1270. This phrase is not applicable to the Williams case, as testimony from Dr. McGarry showed that the mutilation and excision of the victim's vaginal and anal canal occurred while she was still alive and not yet a corpse. Therefore, this Court holds, as it did in Conner, that this assignment of error is without merit.
Williams' other three complaints addressing the alleged inadequacy of S-3 are: (1) the narrowing instruction failed to speak exclusively to his moral culpability; (2) the instruction was imperative or


violence to *1194 the person." Prior to trial, Williams moved in limine to prohibit the State from demonstrating to the sentencing jury that the defendant's prior felony conviction for armed robbery involved the cutting of the victim's throat with a knife. A similar issue focusing upon the admissibility of the prior felony conviction has been raised in Issue VIII. The discussion here should be read in harmony with that discussion.
The State responded to the defendant's motion in limine as follows:
BY MR. BURDICK: Judge he was convicted in '73 of armed robbery. He used a knife and he cut a man's throat then. [N]ow, as far as the conviction, that's admissible in the aggravating, the sentencing phase. The State would not at this time go into the fact thatdeath was suffered by the victim.
With respect to the admissibility of photographs to help establish the (5)(h) aggravator, this Court stated the following in Shell v. State, 554 So.2d at 902, "[t]he pictures themselves provide graphic proof of the atrocious nature and extent of Mrs. Johnson's injuries, which gave evidentiary value to the aggravating circumstance of acts of an `heinous, atrocious, and cruel' nature." See also Mackbee v. State, 575 So.2d 16, 32 (Miss. 1990) (emphasis added) ("Although the state should not attempt in every case to enter into evidence photographs of autopsied body parts, or body parts in general, these pictures were essential in this case in piecing together the puzzle of Montgomery's murder.").
This Court finds that the photographs were relevant and of probative value to assist


requirement for mitigating circumstances." Shell, 554 So.2d at 905.
It is important to note that the instruction Williams contends is flawed tracks the instructions given in Willie v. State, 585 So.2d 660 (Miss. 1991). In Willie the Court found that "the jury was instructed to unanimously find aggravating circumstances, but not mitigating circumstances. The instructions were proper... ." Id. at 682. Also, in Hansen v. State, 592 So.2d 114, 150 (1991), this Court held that since the mitigating portion of the instruction did not contain the words "unanimous" or "unanimously" as did the aggravating circumstances portion, the instruction contained no error. Williams' criticism is devoid of merit.
Second, Williams objects now, as he did at trial, that the mitigating circumstance found in Miss. Code Ann. ง 99-19-101(6)(c) was without aFor many years this Court has held that trial errors cannot be raised in this Court for the first time on appeal. See e.g. Jefferson v. State, 386 So.2d 200, 202 (Miss. 1980) (holding that errors not presented in motion for new trial or not raised in trial court could not be raised in this Court for first time on appeal). In Leverett v. State, 197 So.2d 889, 890 (Miss. 1967) (quoting Collins v. State, 173 Miss. 179, 180, 159 So. 865, 865 (1935)), the Court held the following:
The Supreme Court is a court of appeals, it has no original jurisdiction; it can only try questions that have been tried and passed upon by the court from which the appeal is taken. Whatever remedy appellant has is in


said about appellate review or that this case would be subject to such review. The prosecutor was referring to the time at hand, the time just before when the jury would go into deliberations. The comment complained of was nebulous. This issue is without merit.

*1205 3. Voir Dire Questions
Williams argues that the State impermissibly exacted from the prospective jurors a promise that they would impose the death penalty if the State proved its case. He identifies four such questions that he perceives as extracting this promise. However, Williams failed to object at that time. "Counsel may not sit idly by making no protest as objectionable evidence is admitted, and then raise the issue for the first time on appeal. If no contemporaneous objection is made, the error, if829 (Miss. 1994).
Foster v. State, 639 So.2d 1263 (Miss. 1994).
Conner v. State, 632 So.2d 1239 (Miss. 1993).
Hansen v. State, 592 So.2d 114 (Miss. 1991).
[*]Shell v. State, 554 So.2d 887 (Miss. 1989), Shell v. Mississippi, 498 U.S. 1, 111 S.Ct. 313, 112 L.Ed.2d 1 (1990) reversing, in part, and remanding, Shell v. State, 595 So.2d 1323 (Miss. 1992) remanding for new sentencing hearing.
Davis v. State, 551 So.2d 165 (Miss. 1989).
Minnick v. State, 551 So.2d 77 (Miss. 1989).
[*]Pinkney v. State, 538 So.2d 329 (Miss. 1989), Pinkney v. Mississippi, 494 U.S. 1075, 110 S.Ct. 1800, 108 L.Ed.2d 931 (1990) vacating and remanding Pinkney v. State, 602 So.2d 1177 (Miss. 1992) remanding for new sentencing hearing.
[*]Clemons v. State, 535 So.2d 1354 (Miss. 1988), Clemons v. Mississippi, 494 U.S. 738, 110 S.Ct. 1441,


[],
   "source": [
    "import tensorflow\n",
    "from tensorflow import keras\n",
    "\n",
    "from keras.models import load_model\n",
    "import numpy as np\n",
    "from keras.utils.generic_utils import CustomObjectScope\n",
    "from keras import backend as K\n",
    "import tensorflow as tf"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
    "with CustomObjectScope({'relu6': tf.nn.relu6}):\n",
    "    model = load_model('ADD_H5_MODEL_PATH')"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": null,
   "metadata": {},
   "outputs": [],
   "source": [
uveitis involves macrophages and epithelioid cells and non-granulomatous uveitis is predominantly defined by a lymphocyte and plasma cell response \[[@CR4]\]. To date, several studies have demonstrated an association of RP with a form of non-granulomatous uveitis called Fuchs' heterochromic iridocyclitis (FHIC) \[[@CR5]-[@CR9]\]. This form of anterior uveitis is characterized by stellate endothelial keratic precipitates (KPs) and atrophic changes in the iris. More recently, two studies have confirmed an association between Usher syndrome and FHIC \[[@CR10],[@CR11]\]. Furthermore, a recent study reported a case of non-granulomatous uveitis that was distinct from FHIC in a patient with Usher syndrome \[[@CR3]\].

While associations between Usher syndrome and FHIC have been described and observed in patients, the uveitis typically presents in a unilateral manner. To the best of our knowledge, a case of granulomatous


sclera and conjunctiva were not injected. Several small, round KPs were observed on the inferior corneal endothelium in her right eye; however, the anterior chamber was quiet and deep. In the inferior aspect of her left corneal endothelium there were numerous large, greasy-white mutton-fat KPs (Figure [1](#Fig1){ref-type="fig"}A). There were 2+ cells based on Standardization of Uveitis Nomenclature classification \[[@CR12]\] but no flare in the anterior chamber of her left eye. Her irides were round and flat with no evidence of posterior synechiae or heterochromia. Both eyes had posterior subcapsular cataracts (Figure [1](#Fig1){ref-type="fig"}B) and there were occasional pigmented anterior vitreous cells in her left eye. A retinal examination revealed pale optic nerves with arteriolar attenuation and mid-peripheral bone spicule pigment distribution. There were no signs of pars planitis or retinitis withmutations in these genes can lead to functional impairment with significant quality of life implications, making this an important condition to recognize and accurately diagnose.

Several studies have demonstrated an association between RP, the main ocular phenotype in Usher syndrome, and FHIC \[[@CR5]-[@CR9]\]. The presentation of anterior uveitis in FHIC is typically unilateral and chronic, with patients often lacking any symptoms. A characteristic slit-lamp finding involves stellate KPs on the corneal endothelium, providing further evidence for this non-granulomatous form of uveitis. While the majority of studies that observed FHIC in patients with RP described unilateral KPs as expected, Sandinha *et al.* reported a case of bilateral stellate KPs \[[@CR8]\].

More recently, studies have demonstrated an association between Usher syndrome and FHIC \[[@CR10],[@CR11]\]. Lichtinger *et al.* performed a retrospective analysis of


{#Sec4}
==========

We have reviewed Usher syndrome: a heterogeneous condition that represents the most common inherited cause of combined vision and hearing loss. Deficits typically manifest early on in a patient's life and the condition can have a significant impact on quality of life. As a result, early detection with an accurate diagnosis is especially important.

While an association between Usher syndrome and non-granulomatous uveitis has been described, our finding of bilateral uveitis is a rare occurrence. Furthermore, to the best of our knowledge, we are the first to report granulomatous uveitis as a finding in Usher syndrome. Our patient demonstrated numerous mutton-fat KPs on her corneal endothelium that could not be attributed to any known cause. We hope that this illustration of a rather atypical finding in a patient withbeen shown to be dynamic across cell types, requiring the coordinated binding of cofactors or specific configurations of the underlying chromatin. Moreover, TF binding frequently occurs in the absence of any discernible motif instance ([@gkt1249-B7],[@gkt1249-B8]) or to 'hot-spots' where several factors are simultaneously found ([@gkt1249-B9]). Understanding this complex binding necessitates identifying the underlying sequence features responsible. To address this need, we have performed a systematic, motif-centric analysis of hundreds of TF binding experiments made available as part of the human ENCODE project ([@gkt1249-B8],[@gkt1249-B10]). As part of this, we provide a collection of motifs for each assayed factor, both taken from the literature and through *de novo* discovery, and also an annotation of motif instances genome-wide, which may be used to pinpoint the specific regulatory bases in regions bound


by TFs.

We found that no single algorithm or database comprehensively assays the motifs relevant to the binding diversity surveyed by ENCODE. Therefore, our approach was to collect motifs from several literature sources ([@gkt1249-B11]) and supplement them with motifs discovered *de novo* on the data sets themselves using five established tools ([@gkt1249-B17]). Although this general approach of using multiple motif discovery tools is popular \[e.g. ([@gkt1249-B22])\], its application to this number of data sets is unprecedented and permits the identification of TFs that are likely to be interacting or participating in common pathways.

This work is accompanied by a web interface for browsing the discovered and literature motifs along with their enrichments ([Figure 1](#gkt1249-F1){ref-type="fig"}; <http://compbio.mit.edu/encode-motifs>). In addition to the browsing interface, we provide several data files including all motif matricesused. The outside ring indicates the experimental data sets (one tick for each of 427), which are separated into 123 transcription factors (second ring). The TFs are further grouped into 84 factor groups (third ring). We are able to find a matching discovered motif for 41 of the 56 factor groups with a known motif; 29 of these 41 factor groups have additional discovered motifs that may be associated with cofactors. For all but 1 of the 15 factor groups where the known motif is not recovered we still find enriched discovered motifs. We also discovered enriched motifs for 17 of the 28 factor groups without a known motif. (**b**) Recovery of known motifs by each of the discovery tools. Performance of discovery in terms of number of


factor groups for which the known motif was recovered. A motif is considered a match if it matches any of the known motifs for a factor group (see [Supplementary Methods](http://nar.oxfordjournals.org/lookup/suppl/doi:10.1093/nar/gkt1249/-/DC1) for details on how matches are computed). The number of additional factors that have a match is shown with each additional motif (only three motifs are taken from each individual method, whereas we have up to 10 for the pipeline). The number of factor groups with no motif match is shown in parenthesis. When multiple data sets exist for a factor group, the fraction that matches is used in computing its contribution for computing the performance of the individual tools.

We exclude from the discussion below motifs that we consider unlikely to be relevant to our analysis, while maintainingthem as part of the overall resource where they may be useful. These include 46 discovered motifs that are either low-complexity (e.g. dinucleotide repeats) or consistently have weak enrichment (\<2) and do not match known motifs ([Supplementary Table S1](http://nar.oxfordjournals.org/lookup/suppl/doi:10.1093/nar/gkt1249/-/DC1)). These are likely a consequence of slight biases in the discovery pipeline, or are due to real, but relatively weak, specificity for the factor. We also exclude an additional 36 motifs that have a weak similarity to the known motif for the factor but for which a better matching and enriched motif is also found ([Supplementary Table S2](http://nar.oxfordjournals.org/lookup/suppl/doi:10.1093/nar/gkt1249/-/DC1)). These are most frequently seen for longer motifs that can be broken up into recognizable, but globally dissimilar, patterns that are not captured by our automatic exclusion criteria (see [Supplementary Methods](http://nar.oxfordjournals.org/lookup/suppl/doi:10.1093/nar/gkt1249/-/DC1)).


examined by inspecting only the TSS-proximal enrichment.

The motif most enriched in multiple data sets was the TPA DNA response element (TRE; TGA\[C/G\]TCA), which is recognized by the AP1 TF when it is formed by FOS/JUN dimers ([@gkt1249-B31]) and other factors including MAF and NFE2. The enrichment of the TRE in a data set is often stronger than that of even the known *in vitro* sequence specificity and may arise from a number of phenomena, including (i) a cooperatively interaction with AP1, (ii) competition with AP1 for the same binding sites, leading to a potentially repressive role for the TF or (iii) reuse of binding sites due to, for example, accessibility of chromatin. We find a motif matching the TRE motif for 20 factor groups (AP1_disc3, AP2_disc1, BATF_disc1, BCL_disc2,sets: IRF1 binding in K562 cells stimulated by IFNa (viral innate response) or IFNg (viral, bacterial and tumor control); IRF3 in HepG2, GM12878 and HeLa-S3; and IRF4 in GM12878. The most strongly enriched motif (IRF_disc1, matching NFY) is highly enriched (\>20-fold) for all three IRF3 data sets and IRF1 in K562 under IFNg stimulation. This suggests that binding of IRF to NFY sites occurs only under specific conditions and by only some IRF members and potentially expands on the previously documented interaction of NFY and IRF2 at a single promoter ([@gkt1249-B40]). IRF_disc4, which matches SP1, is enriched in the same cell types, albeit at much lower levels. IRF_disc3, which matches the known IRF consensus, shows weak-to-no enrichment in these data sets, but shows an enrichment of 8.8-fold for


assayed cell lines for a given factor. FOXA_disc1, for example, matches the known FOXA motif, indicating that FOXA's own motif also plays an important role in its specificity. Most of the motifs we identify for RNA Pol2 machinery (TAF1, GTF2B, GTF2F1 and TBP) are enriched in all cell lines, including the known TATAAA motif (TATA_known2). Also, TATA_disc1, disc6 and disc8 have consistent enrichment and match the known motifs for YY1 (which is known to be important in establishing transcription) ([@gkt1249-B82]), NFY and ETS. The top discovered motif BCL_disc1 matches the known ETS motif and is also enriched across data sets.

Interestingly, we find that the TRE motif is found and enriched in a cell line-specific manner for several factors, but for different cell lines. For example, HMGN3_disc1 is enrichedstage shifts (p<.05), stage 1 percentage of total sleep time (p<.05), stage 2 duration (p<.05), stage 3 latency (p<.05), stage 4 duration (p<.01) and stage 4 percentage of total sleep time (p<.01). There was significant positive correlation of REM percentage of total sleep time with BPRS total score (r(s) = .488, p = .029) and PANSS positive score (r(s) = .583, p = .007), whereas significant negative correlation of REM latency was found with BPRS total score (r(s) = -.640, p = .002) and PANSS positive score (r(s) = -.657, p = .002) in the patients. Slow wave sleep deficits are a possible trait marker in patients with schizophrenia, which needs replication in further studies.


groups. HS in the MIVAT operations is safe and facilitates dissection, allowing for a significant decrease in operative time. Other benefits, such as lower blood loss, a scar a few millimeters shorter, or a slightly better early cosmetic result, are offered at slightly increased costs.product," and received loading tickets reflecting the amount of product pulled.  The exchange terminals then forwarded copies of the loading tickets to Total, and Total billed Rushin-Davis for the amount of product pulled.

3
When disagreement over management of the partnership arose between Davis and Rushin during the summer of 1981, Davis offered to buy Rushin out.  Commerce Bank of Poplar Bluff, the bank from which Davis sought financing for the deal, requested Davis to provide some proof that Total would permit Davis to take over the partnership's distributor marketing agreements.  Davis therefore contacted Don Wright, the Total regional manager, and asked what was needed to enable Davis to assume the partnership distribution agreements and to release Rushin from the partnership's obligations.  Davis testified that Wright


claim against Davis for money owed because there was no evidence disputing the fact that Davis received at least some product for which he has never paid.  Because Davis did not submit to the jury any affirmative defenses to that debt, Total argues, Total was clearly entitled to recover under the trial court's instruction and the evidence presented at trial.2

11
Davis first attempts to support the jury verdict by pointing to the inconsistencies in the amounts Total claimed Davis owed and the difficulty Total's credit manager had in explaining how Total determined that amount.  In light of these inconsistencies, Davis argues, the jury was entitled to find against Total.  Although Davis disputes his liability for the product Rushin-Davis received from September 1 through September 17, 1981,that Davis' reliance on Total's misrepresentation was justified.

26
It is true, as Total contends, that under Missouri law a fiduciary relationship does not ordinarily exist between an oil and gas company and its distributors.    See Sagehorn v. Phillips Petroleum Co., 648 S.W.2d 647, 650 (Mo.Ct.App.1983).  The trial court in the case at bar, however, did not instruct the jury that a fiduciary relationship existed between Total and Davis nor did the instruction invite the jury to find that such a relationship existed.  Rather, the trial court merely instructed the jury that in determining whether the alleged representation was material and whether Davis' reliance was reasonable, it could consider the business relationship between Total and Davis.  The relationship between the parties is clearly an


a great Weekend...it is Summer! -Stone

Dave, Scottish Electric Band. I will check it out. This is the great thing about this hobby...I love so many different genre's...it would take two lifetimes to get to it all! I keep discovering an discovering...it never gets old for me. I don't know what I would do without my Music in this crazy world... .

After Sir Paul at Target Field 8/2....(the sound was good too)...I did go to Dave Koz Summer Horns 8/17...sound was good....good deep bass too. Then, Toby Keith 8/21...sound so so...he was a little hammered too.Also, Boston on Friday, 8/29....sound sucked! I had Huey Lewis an the News at this same Venue back in May...an his sound guy(s)...had it nailed beautifully! So, no excuse sucky Boston sound guy(s).

2) .........awesomemy favorite “mom” podcast) and am thoroughly enjoying hearing their viewpoints and experiences as the primary caregivers in their families. It’s definitely affected, in a positive way, how I see and treat my husband as a father to our kids, and I thought I was doing pretty well! Sounds like you had a similar experience at the conference. Wouldn’t it be great if every parent had a chance to be the primary caregiver and the primary breadwinner at different times, to truly understand each other’s sides and the many facets of parenting? I think that would open up so many peoples’ eyes. Thanks for your continued thought-provoking posts, Liz.

sometime in the last 5 years, I realized… just as I am not my mother (love her, respect her, adore


Left upper pulmonary vein connected to the persistent left superior vena cava and the left atrium.
Persistent left superior vena cava (PLSVC) is the most common anomalous thoracic venous drainage. A PLSVC usually drains into the right atrium through a dilated coronary sinus. It is rare that a PLSVC flows directly into the left atrium, and even rarer that it connects to the left upper pulmonary vein (LUPV). We report a case, wherein the LUPV connected to both the PLSVC and the left atrium.one.

A:

Your final screenshot indicates that you are using your venv properly, which you named "py3". There are lots of ways to launch your Python script from VSCode:

Right click the file in VSCode's file Explorer and select "Run Python File in Terminal"
Click the debugger menu and set up a launch.json file to ensure you are using your venv. This method has the added advantage of allowing you to step through your code.
Set up a tasks.json file to create a build task using your preferred venv.

Based on the back-and-forth comments we exchanged, it appears that you did not launch using any of these standard methods, which could explain why your venv is not being picked up.


their summer palace in Nagarkot in order to enjoy the vista daily.

Nagarkot is only 20km from Kathmandu, but if you choose to trek, it is a 4-6 hour trekking journey (depending upon skill level). The trek actually starts at the temple of Changu Narayan in the Kathmandu Valley. The temple, a a UNESCO World Heritage Site, is one of the oldest Hindu temples in the valley, dating back to the 4th century. A stone slab discovered in the vicinity of the temple dates to the 5th century, and is the oldest such inscribed stone ever found in Nepal. Around the temple is a neighboring village where one begins to get a sense of Nepalese village life – children playing in the dusty lanes, women washing each other’s hairas you know anything, all right?" "No problem." "CAMERA CLICKING" "Excuse me." "Are you an art student?" "Am I that obvious?" "No, no, no." "LAUGHS" "Where do you go?" "Um, Saint Martin's." "No?" "!" "LAUGHS" "Me too." "I went to Saint Martin's." "Really?" "Yeah." "It's a small world, or what?" "Um..." "What are you doing?" "Um..." "Fine art... or...?" "No, textiles." "Oh!" "Yeah, we have to, um, design a print that somehow evokes London." "Oh, well... you came to the right place for that, eh?" "I mean this, this is... is..." "London." "It used to be a quiet little lane, lined with elm trees and so on, but they've been selling stuff here since 1608." "Then in the 17th century, the Huguenots arrived." "18th century, it becomes, like,


a centre for cloth-making, and then in 1830, they tried to change the name." ""Petticoat" was considered too raunchy for the Victorians." "But it didn't work!" "Petticoat Lane endures." "Are you, like, a local historian?" "No, no, no, no." "I just..." "I love the place." "You can feel the time, like layers of time, strata of time, a big cake of time." "No, it's magic." "It's got magic to it." "Hey... do you want to see something really cool?" "No." "Um, no, I'm fine, thanks." "The most London thing ever." "No." "Most London thing you'll ever see." "I'm fine!" "Thank you." "SHE GASPS AND SCREAMS" "SPLUTTERING" "DISTORTED VOICE He is the sunrise." "He loves everyone." "He is the sunrise." "He loves everyone." "He is the sunrise." "He loveslucky." "Listen." "Look at me." "Nothing's going to happen to you, all right?" "Yeah, who says?" "You?" "Yeah, me." "They do know where I live, you know." "People like that, they always do." "Come on." "Mark, I wouldn't do this unless I absolutely had to." "Do what?" "John, who is this?" "Where am I?" "What part of London is this?" "Well, if I told you that... it wouldn't be a safe house, would it?" "And you wouldn't be in protective custody." "And besides, it's only for an hour." "HE GROANS" "You do know what they'll do when they find me, don't you?" "PHONE RINGS" "BEEP" "WOMAN:" "Pick up, come on, come on." "Bitch, pick up!" "All right, now listen." "Now, have you done as you were asked?" "Have


In U.S. Pat. No. 5,694,471, Chen et al. disclose a system for preventing fraudulent use of identity or transaction cards. The cards are chip cards that include an integrated circuit with a unique serial number permanently and unalterably burned into the chip, and having sufficient storage capacity for a card issuer identification (ID) number, user information (name, account number, signature image, etc.), the public key of a public-private key pair, a digital signature, and a personal identification number (PIN) derived from a user password. To initialize a card, a one-way hash function is performed on the issuer ID and user information to obtain a checksum, an XOR operation is performed on the checksum and card serial number to obtain a composite result, and this result is enciphered usingbeen unavailable to systems that use passive storage media and, thus, in comparison to smart cards the passive media systems have been deemed too insecure for those transactions which are vulnerable to fraud or forgery (e.g., financial transactions.)
It is an object of the present invention to provide data security methods and systems for achieving secure transactions when using passive storage media, such as optical memory cards.
It is another object of the present invention to provide both hardware and software/firmware security measures to deny unauthorized access to cryptographic keys and to prevent interception of decrypted data streams.


The Walking Dead season seven kickstarts its final furlong with an episode that seems to be largely dedicated to Carol Peletier (Melissa McBride) and the folk over at the Kingdom.

Titled 'Bury Me Here,' it can be deduced from the episode's high-octane trailer that this week's outing could be designed to get King Ezekiel's people in the right place ahead of the oncoming war against Negan (Jeffrey Dean Morgan)and The Saviours.

Ezekiel (Khary Payton) appears to have had enough playing ball with The Saviours - the trailer's climax shows him raising a gun to them during one of their typically-heated supply runs.

Fresh from being lied to by Daryl (Norman Reedus) about the safety of their friends, Carol could well be on the cusp of discovering the truth, leaving her abodeto find Morgan (Lennie James) - presumably to find out what really happened with Negan in the season seven premiere.

You can watch a clip from the new episode above, and the trailer below.

The Walking Dead Season 7 Episode 13 Bury Me Here Promo

The episode's ominous synopsis reads: “Keeping with the routine supply drop-off, a group of Kingdommers delivers goods to The Saviours. Things don't go as planned.“

The most shocking Walking Dead moments Show all 10 1 /10 The most shocking Walking Dead moments The most shocking Walking Dead moments Sophie's a walker (season 2, episode 7) Much of season two's opening half is spent looking for Sophia, the missing daughter of Carol (Melissa McBride). Turns out she was locked up in Hershel's barn as a zombie all along.


The most shocking Walking Dead moments Shane reanimates without being bitten (season 2, episode 12) When Carl (Chandler Riggs) guns down a deranged Shane (Jon Bernthal) to protect his father, the shock arrives when he manifests into a walker despite not being bitten; turns out everyone's infected with the virus and will turn whichever way they die. The most shocking Walking Dead moments Axel's bullet to the eye (season 3, episode 10) A character introduced in the show's prison arc, Axel is a reformed prisoner who strikes up a friendship with Carol - until he's gunned down mid-sentence. The most shocking Walking Dead moments Carl kills Lori after she gives birth (season 3, episode 4) Lori (Sarah Wayne Callies) goes into labour at the very moment a zombieQ:

android drawable marker nullExceptionPointer

I have my drawable object which works fine first time, but when I try to use it second time(clear map overlays list)  nullExceptionPointer occurs.
my code:
Drawable myMarker=this.getResources().getDrawable(R.drawable.marker);;

then in many place I use (or rather try to use) myMarker.But it crushes.

A:

I was trying to use Drawable from one activity in another activity. It was not working until I made it static.