these numbers every day since the start of this recession.

The recession hit these programs with a double whammy: dried up funding (from governments and private donors) and increased need. I witnessed this personally at the end of 2009 and most of 2010. I was working for a gang intervention program in Los Angeles called Homeboy Industries. It’s an amazing organization, run by Greg Boyle, S.J., that offers many services completely free of charge including tattoo removal (the most popular service), counseling, twelve step meetings and even a charter high school. And most importantly – especially during this recession – they employ hundreds of men and women with barriers to employment and help train them to do various types of jobs. This is an especially important part of Homeboy’sabout 100 employees, but the program is operating as a shadow of its former self. And that is a tragedy for the city of Los Angeles.

This is why the social safety net is so needed right now. Homeboy Industries keeps people out of jail. It is a community, a source of hope for thousands of people in Los Angeles. While programs like Food Stamps, the TANF emergency fund and Section 8 housing (to name a few) don’t solve the problem, they can provide support for programs like Homeboy which are on the front lines battling against the disillusionment that accompanies poverty and marginalization.

When I hear that 29.9% of single mothers are living in poverty, I picture the line cook in the Homegirl Café who won’t be able to


program is free software; you may redistribute
    # it and/or modify it under the same terms as Ruby itself.
    #
    class RR
      include Net::DNS::Names

      # Regexp matching an RR string
      RR_REGEXP = Regexp.new("^\\s*(\\S+)\\s*(\\d+)?\\s+(" +
                               Net::DNS::RR::Classes.regexp +
                               "|CLASS\\d+)?\\s*(" +
        unless args.has_key? :name
          raise RRArgumentError, "RR argument error: need at least RR name"
        end

        @name  = args[:name].downcase
        @ttl   = args[:ttl] ? args[:ttl].to_i : 10800 # Default 3 hours
        @type  = Net::DNS::RR::Types.new args[:type]
        @cls  = Net::DNS::RR::Classes.new args[:cls]

        @rdata = args[:rdata] ? args[:rdata].strip : ""
        @rdlength = args[:rdlength] || @rdata.size

        if self.class == Net::DNS::RR


h e text o f S. 114 as introduced in the Senate in 1979 appears at 125 C ong. Rec. 782-83
(January 23, 1979). Ed.
   1 See 18 U.S.C. § 34 (destruction o f m otor vehicles o r m o to r vehicle facilities w here death results);
18 U.S.C. § 351 (assassination o r kidnapping o f a M em ber o f C ongress); 18 U.S.C. § 794 (gathering or
delivering defense inform ation to aid a foreign governm ent); 18 U.S.C. § 1111 (m urder in the first
degree w ithin the special m aritim e and territorial jurisdiction o f the U nited States); 18 U.S.C. § 1716
(causing death o f an o th er by mailing injurious articles); 18 U.S.C. § 1751 (m urderjustice system is incapable of
guaranteeing objectivity and evenhandedness. Chief Justice Burger and
Justices Rehnquist and White dissented, warning that the Court should
not put itself in the role of second-guessing state judges and juries.
   S. 114 seeks to establish constitutional procedures for the imposition
of the death sentence upon conviction of federal crimes for which the
death penalty is authorized. The bill would amend Title 18 of the
United States Code, rather than the Federal Rules of Criminal Proce
dure, as some previous bills have proposed.10 It provides that after
conviction of a capital offense the defendant shall be subject to the
death penalty only if a hearing is held in accordance with specified
procedures. The hearing would be conducted before the jury which
determined the defendant’s guilt, unless, under specified circumstances,
a new jury must be


any death penalty legislation is bound to raise difficult
constitutional questions. Some of the questions identified below were
raised by prior legislation and have been the subject of extensive testi
mony before congressional committees. Other issues discussed here are
raised by provisions in S. 114 which did not appear in the prior
legislation. As with the prior bills, it is not possible to state definitively
how the Court would resolve each of the issues raised by S. 114. We
have attempted to identify provisions likely to be challenged as consti
tutionally inadequate and to indicate where possible how we think these
issues would be resolved under the case law to date.

I. Determination by Majority Vote o f Aggravating and Mitigating Factors

  Both S. 1382 and H.R. 13360 required unanimity in all jury findings.
S. 114, however, providesmakes it clear that open and far-
ranging argument is possible even when the rules of evidence are
observed. The Judiciary Committee report on the bill does not state
why this change was made. S. Rep. No. 554, 96th Cong., 2d Sess. 15
(1980). It merely notes that both parties are permitted to present argu
ments as to the adequacy of the information.

4. Vagueness o f Language Specifying Aggravating and Mitigating Factors

    S. 114 specifies that one of the aggravating factors the sentencer shall
 consider is whether “the defendant committed the offense in an espe
 cially heinous, cruel, or depraved manner.” The issue raised by this
 language is whether it is so broad and vague as to give no guidance to
 the jury, yielding an arbitrary result and thus violating


punishment retain it for a few exceptional crimes such as
those related to the security of the state. U.N. Economic and Social
Council, Capital Punishment: Report o f the Secretary General, para. 18,
U.N. Doc. E/5242 (1973). More specifically, the report notes, “The
most common exceptional crimes punishable by death are treason and
crimes relating to the security of the State.” Id. at para. 32. Tables
appended to the report show that the majority of member nations of
the United Nations retaining capital punishment—about 100—and that
 15 other nations, while abolishing capital punishment for ordinary
crimes, retain it for exceptional crimes. Id. at Annex 1, 2-3. A 1975
update of this report shows that the picture remains largely unchanged.
U.N. Economic and Social Council, Capital Punishment: Report o f the
Secretary General, U.N. Doc. E/5616 (1975) Annex 1, 2-3. // MULTIPLY, ADD, SEPARATOR, SUBTRACT, DECIMAL, DIVIDE,
    // F1 to F24, NUM_LOCK, SCROLL_LOCK, COMMA, PERIOD, SLASH, BACK_QUOTE,
    // OPEN_BRACKET, BACK_SLASH, CLOSE_BRACKET, QUOTE, META
    //
    // Additionnally, ANY will return true for any key
    // and NONE will return true for no keys
    function isKeyDown(keyName: string): boolean;
    function wasKeyJustPressed(keyName: string, options?: { autoRepeat?: boolean; }): boolean;
    function wasKeyJustReleased(keyName: string): boolean;

    function getTextEntered(): string;

    function isGamepadButtonDown(gamepad: number, button: number): boolean;
    function wasGamepadButtonJustPressed(gamepad: number, button: number): boolean;
    function wasGamepadButtonJustReleased(gamepad: number, button: number): boolean;
    function getGamepadButtonValue(gamepad: number, button: number): number;


combination therapy was used to rapidly clear persistent MSSA bacteremia. An in-depth analysis of the synergy of the two drugs was performed at the level of the host innate immune system, as well as against a panel of clinical bloodstream isolates, demonstrating that ertapenem plus cefazolin requires clinical evaluation in the treatment of refractory MSSA bacteremia.

MATERIALS AND METHODS {#sec2}
=====================

Bacterial strains and *in vitro* antimicrobial susceptibility assays. {#sec2-1}
---------------------------------------------------------------------

The index MSSA isolate for this study, rus276, was the original bloodstream isolate obtained from a patient with refractory MSSA bacteremia. It was examined using all the methods of susceptibility testing described below. CZ and ETP were purchased commercially (Sandoz Inc., Princeton, NJ, and Merck, Kenilworth, NJ, respectively). The well-characterized S. aureus strains SA113 (ATCC 35556) (MSSA) ([@B6]), MW2 (USA 400) (MRSA)of the index isolate, rus276, in the assay, which showed synergy by checkerboard analysis and kill curves. ETP and CZ MICs for the MSSA and MRSA strains were determined by CLSI broth microdilution methods ([@B11]). Assays on rus276 were performed twice on different days, and assays on the MSSA and MRSA clinical strains were performed once.

Population analyses. {#sec2-2}
--------------------

MSSA rus276 was grown to late stationary phase (18 to 20 h) in BHI or MHII broth and either plated directly onto BHI agar or MHA for the high-inoculum experiments or diluted 1,000× in fresh BHI or MHII broth and plated onto BHI or MHA plates for the low-inoculum condition. Ten-microliter aliquots were plated in duplicate with 10^0^ to 10^7^ dilution of each sample. The plates contained 2, 1, 0.5, 0.25,


presence or absence of LL-37. The greatest killing was seen with the combination of the two antibiotics in the presence of LL-37 ([Fig. 4A](#F4){ref-type="fig"}). Interestingly, no synergy was seen between ETP and LL-37, whereas CZ alone plus LL-37 showed greater killing than the combination CZ plus ETP. Bacteria were grown in the presence of each antibiotic alone or in combination and subjected to neutrophil killing assays. Significantly increased susceptibility to neutrophil killing at 90 min was seen with combination antibiotic pretreatment compared to no antibiotic or one antibiotic (*P* \< 0.02; Mann-Whitney U test) ([Fig. 4B](#F4){ref-type="fig"}).

![(A) Kill curve assays of MSSA rus276 using human cathelicidin LL-37, CZ, or ETP alone or in combination. (B) Neutrophil killing assays of MSSA rus276 after growth in antibiotic-free medium (control) or mediaA beta-lactamase. In addition, the greater benefit of ETP in protecting the activity of CZ under high-inoculum conditions (shown in the population analysis studies) suggests that ETP may be important in cases where CZ is at high risk of failure due to enhanced beta-lactamase hydrolysis, due to either inoculum size and/or a class A beta-lactamase in MSSA. Future studies of this drug combination will continue to focus on the effect of beta-lactamase types in MSSA and of the bacterial inoculum on the magnitude of the synergistic effect between ETP and CZ, as well as studying the effects of various beta-lactamase inhibitors on ETP-CZ synergy.

Supplementary Material
======================

###### Supplemental material

Supplemental material for this article may be found at <http://dx.doi.org/10.1128/AAC.01192-16>.

This work was supported by a grant from the National Institute of Child


to the stream as a Date object
   * in the Java programming language.
   *
   * @param x the value to pass to the database
   * @exception java.sql.SQLException if a database access error occurs
   * @exception java.sql.SQLFeatureNotSupportedException if the JDBC driver does not support
   * this method
   * @since 1.2
   */
  void writeTimestamp(Timestamp x) throws java.sql.SQLException;

  /**
   * Writes the next attribute to the stream as a stream of Unicode characters.
   *
   * @param x the value to pass to the database
   * @exception java.sql.SQLException if a database access error occurs
   * @exception java.sql.SQLFeatureNotSupportedException if the JDBC driver does not support
     * @exception java.sql.SQLException if a database access error occurs
      * @exception java.sql.SQLFeatureNotSupportedException if the JDBC driver does not support
      * this method
      * @since 1.4
      */
     void writeURL(java.net.URL x) throws java.sql.SQLException;

     //--------------------------- JDBC 4.0 ------------------------

  /**
   * Writes the next attribute to the stream as a String
   * in the Java programming language. The driver converts this to a
   * SQL NCHAR or
   * NVARCHAR or LONGNVARCHAR value
   * (depending on the argument's
   * size relative to the driver's limits on NVARCHAR


* XML value
   *
   * @throws java.sql.SQLException if a database access error occurs,
   * the java.xml.transform.Result,
   *  Writer or OutputStream has not been closed for the SQLXML object or
   *  if there is an error processing the XML value.  The getCause method
   *  of the exception may provide a more detailed exception, for example, if the
   *  stream does not contain valid XML.
   * @exception java.sql.SQLFeatureNotSupportedException if the JDBC driver does not support
   * this method
   * @since 1.6
   */
  void writeSQLXML(SQLXML x) throws java.sql.SQLException;

  //--------------------------JDBC 4.2 -----------------------------

  /**
   * Writes to the stream thedata contained in the given object. The
   * object will be converted to the specified targetSqlType
   * before being sent to the stream.
   *

   * When the {@code object} is {@code null}, this
   * method writes an SQL {@code NULL} to the stream.
   *

   * If the object has a custom mapping (is of a class implementing the
   * interface {@code SQLData}),
   * the JDBC driver should call the method {@code SQLData.writeSQL} to
   * write it to the SQL data stream.
   * If, on the other hand, the object is of a class implementing
   * {@code Ref}, {@code Blob}, {@code Clob},  {@code


to be privileged above all else, but at this point I've officially had it. The state of the current industry is so out of control I don't really even have words to express how stunned and aghast I am by the aggressive, mindless technofetishistic lust that seems to be driving almost everyone on both sides of the Pacific right now. The most blatantly obvious example is the grotesque display that is the current console market: We're supposed to have hardware cycles of 5 years or so between revisions and new machines, but then somebody told Microsoft and Sony about Apple's business model with smartphones and suddenly we're in an era of “mid-generation hardware revisions” for $500 computers. We didn't even get 3 years between the PlayStation 4, toutedmarketing in over a century of trading. I'll come back to them a little later.)

None of this is of course new. Microsoft's strategy with the XBOX One X to push 4K reminds me of what they they tried to pull with the XBOX 360 in 2005 to push 1080p (the one that forced them to rebrand and slash prices a couple years later). And there is, of course, a precedent for this going back decades. I like to pick on Sony here for how they set the discourse for the fifth generation with the original PlayStation, but I probably also have to blame SEGA of America for how they marketed the Genesis in the United States, openly bullying Nintendo and Nintendo's fans by saying that faster processors and


to Capcom these past few months, that they're somehow “abandoning” some special “relationship” the two companies supposedly had over the past two generations, that's silly-I'm merely expressing concern that Capcom is shooting themselves in the foot because of some potential hangup I fear they're having about tech specs. There's certainly no reason the Switch shouldn't be getting the likes of The Disney Afternoon Collection or Mega Man Legacy Collection 2, and they seem genuinely disinterested in the new platform: The Switch port of Super Street Fighter II was lackluster at best, and Capcom seemed shocked that the console was actually selling well, having to pledge their support to the system noticeably later than other publishing houses. I'm not even a fan of Capcom's games, but their business decisionswerve towards elitism and classism that's only gotten worse in the past few years. Famous composer David Wise, a man whose work I typically respect, gave an interview a few months back about his time with Rare and Nintendo in the late 80s and early 90s where he actually called the NES and Famicom a “doorbell” (in reference to the consoles' sound cards, which actually were based around the same technology used in doorbells) and expressed his constant frustration that Nintendo's hardware didn't give him the freedom of CD audio technology. This echoes the complaints of many, many other developers over the years, is the same sentiment behind why so many of them jumped ship to the original PlayStation in 1995, and is strikingly reminiscent of criticisms leveled


where games are indistinguishable from reality? And if so...Why? What's wrong with reality such that we feel we need to craft an artificial alternative to it? This is all beginning to sound alarmingly like Singularitarianism, and indeed Mizuguchi-san even *uses* the term “singularity”. Rez's creator seems to want to create a video game that can serve as a spiritual awakening, and I think using that language leads us to some dangerous places. No matter how powerful a work of art Rez may be (and I'm very much looking forward to playing it myself, as I never had the chance to before), it remains just that: A work of art. Art is by definition imperfect, a flawed artifice created as a form of self-expression for some very tangible creators.USS L-2 (SS-41)

USS L-2 (SS-41) was an L-class submarine of the United States Navy.

Description
The L-class boats designed by Electric Boat (L-1 to L-4 and L-9 to L-11) were built to slightly different specifications from the other L boats, which were designed by Lake Torpedo Boat, and are sometimes considered a separate class. The Electric Boat submarines had a length of  overall, a beam of  and a mean draft of . They displaced  on the surface and  submerged. The L-class submarines had a crew of 28 officers and enlisted men. They had a diving depth of .

For surface running, the Electric Boat submarines were powered by two  diesel engines, each driving one propeller shaft. When submerged each propeller was driven by a  electric


: "{0} vahkku dás ovdal",
        "other" : "{0} vahku dás ovdal"
      }
    },
    "second" : {
      "future" : "{0} sekundda siste",
      "current" : "dál",
      "past" : {
        "one" : "{0} sekunda áigi",
        "other" : "{0} sekundda áigi"
      }
    },
    "hour" : {
      "future" : "{0} diimmu siste",
      "current" : "dán diimmu",
      "past" : {
 Liefstyle Options

For more information about campus living at MorningStar please contact Dave Herr at 877-748-6937 or dherr@morningstarministries.org.

A growing number of people from across the nation and around the world are coming together to live in the Ft. Mill, South Carolina area to be a part of what God is doing at MorningStar Ministries. In response to this MorningStar and Heritage Lifestyle Communities are offering a variety of residential choices right on MorningStar's campus.

Heritage Courts

A wide variety of gracious and well appointed one and two bedroom residences are available. Beautiful views overlook spacious lawns and trees or our manicured courtyard. We offer five floor plans to choose from. Prices range from under $50,000 and to just below $200,000.

The Heritage Towers

Heritage Towers is the future development of our 21-story landmark


[Effect of hydraulic load distribution on sewage treatment efficiency of earthworm bio-filter].
Effect of hydraulic load distribution on sewage treatment efficiency of earthworm bio-filter was studied by analyzing influent and effluent of earthworm bio-filter and earthworm behaviors. The results show that when hydraulic load varying from 2.0 m3/(m2 x d) to 6.0 m3/(m2 x d), the concentration of each pollutant in earthworm bio-filter effluent increases slowly and is little effected by hydraulic load. When hydraulic load reaches 6.7 m3/(m2 x d), the concentration of COD, BOD5, SS, NH4(+) -N and TP in earthworm bio-filter effluent increases obviously, but the TN concentration in effluent presents descending tendency. The earthworms become rather inadaptable to the living conditions at this operating mode. As hydraulic load increasing, the earthworms' relative ingestive ability issome are a team. If you see yourself, vote for yourself, that’s not cheating; really its fine. If you want your friends to throw a vote your way, they can too so tell them to vote! Spamming the vote box with multiple votes for yourself or favorite in one day is a no-no, though; death lasers will engage. Everyone is allowed to vote once per day (every 24 hours).

The top three winners will get featured on our homepage and be used as our feature image when we announce the winners, forever immortalizing them on our site.

We are excited to announce our brand new Community message boards! What this means is that we have a brand new place where you can discuss the costumes from the convention specifically on


In image reproduction or projection technology, mixed light sources, i.e., sources such as white light sources for electromagnetic radiation of different wavelengths are used as light sources for backlighting, among other things. One can mention, for the sake of example, LCD projection or image reproduction as a field of application. Mixed light serves there for brightening the liquid crystal matrix situated in the image reproduction system or projection system. This matrix has a plurality of individual liquid crystals. Depending on the applied control voltage and the wavelength of the light passing through the crystal, the crystals become transparent. This liquid crystal matrix is generally referred to as a light modulator. By illuminating the light modulator with a mixed light, the image generated by the driving becomes visible andCommands
========

Pipeline Commands
-----------------

Commands used to manipulate pipelines.

Usage:

::

    dataduct pipeline [-h] {create,validate,activate,visualize}

Arguments:

-  ``-h, --help``: Show help message and exit.

Create, Validate, Activate
^^^^^^^^^^^^^^^^^^^^^^^^^^

Usage:

::

    dataduct pipeline {create,validate,activate}
        [-h] [-m MODE] [-f] [-t TIME_DELTA] [-b] [--frequency FREQUENCY]
        pipeline_definitions [pipeline_definitions ...]

-  ``create``: Creates a pipeline locally.

-  ``validate``: Creates a pipeline on Amazon DataPipeline and validates the pipeline.

-  ``activate``: Creates and validates the pipeline, then activates the pipeline.

Arguments:

-  ``-h, --help``: Show help message and exit.
-  ``-m MODE, --mode MODE``: Mode or config variables to use. e.g. ``-m production``
-  ``-f, --force``: Destroy previous version of this pipeline, if they exist.
-  ``-t TIME_DELTA, --time_delta TIME_DELTA``: Timedelta the pipeline by x


sophisticated electronic devices.”

Yesterday Watercare confirmed to Newsroom this is still the case.

Several other Official Information Act requests were made in 2017 about the use of dowsing to various councils through the FYI website. Responses ranged from no, to not being aware if it had been used. A few councils said in the past it may have been used.

“I am connected to the magnetic field, the north and south pole."

Scientists think the movement of dowsing rods or sticks is due to what’s called the ideomotor response where people’s subconscious minds influence their bodies to move, without them consciously realising it's happening. This is similar to how scientists explain how Ouija boards appear to work.

Several studies have been completed to test whether dowsing works. Among them, a 1948 New ZealandIT WOULD BE LIB BY THE LIBS LEAST, PETE, AND THE MAZALATOR.
LEAST, PETE, AND THE MAZALATOR. >> LOOKING FORWARD TO THAT.
>> LOOKING FORWARD TO THAT. WE ARE LAUNCHING MOTHER KNOWS
WE ARE LAUNCHING MOTHER KNOWS BEST.
BEST. WE’RE KICKING THINGS OFF WITH
WE’RE KICKING THINGS OFF WITH MAYE MUSK.
MAYE MUSK. SHE’S ELON MUSK’S MOTHER.
SHE’S ELON MUSK’S MOTHER. SHE ALSO A STAR IN HER OWN
SHE ALSO A STAR IN HER OWN RIGHT.
RIGHT. SHE RECENTLY WALKED THE RUNWAY
SHE RECENTLY WALKED THE RUNWAY IN ITALY AND IS A SOCIAL MEDIA
IN ITALY AND IS A SOCIAL MEDIA SENSATION AT 70.
SENSATION AT 70. >>> NBC SPECIAL ANCHOR MARIA
>>> NBC SPECIAL ANCHOR MARIA SHRIVER SAT DOWN WITH THE MODEL
SHRIVER SAT DOWN WITH THE MODEL AND MEDIA MOGUL.
AND MEDIA MOGUL. >> I DON’T WANT TO BRAG ABOUT
>> I


SET THE TONE AT HOME.
MOM SET THE TONE AT HOME. >> THIS ELEMENT OF JOYFUL
>> THIS ELEMENT OF JOYFUL ATTITUDE TOWARD MAKING A
ATTITUDE TOWARD MAKING A DIFFERENCE, FOCUS ON WHAT YOU’RE
DIFFERENCE, FOCUS ON WHAT YOU’RE PASSIONATE ABOUT.
PASSIONATE ABOUT. MONEY WILL COME.
MONEY WILL COME. SUCCESS WILL COME.
SUCCESS WILL COME. >> Reporter: THAT’S EXACTLY WHAT
>> Reporter: THAT’S EXACTLY WHAT HAPPENED TO KIMBALL AND ELON
HAPPENED TO KIMBALL AND ELON WHEN THEY LAUNCHED THEIR FIRST
WHEN THEY LAUNCHED THEIR FIRST COMPANY IN THE MID 90s.
COMPANY IN THE MID 90s. >> EVERY SIX WEEKS I WOULD COVER
>> EVERY SIX WEEKS I WOULD COVER THEIR COSTS FOR FURNITURE AND
THEIR COSTS FOR FURNITURE AND PRINTING.
PRINTING. >> Reporter: AFTER A
>> Reporter: AFTER A PARTICULARLY ROUGH ALL NIGHTER
PARTICULARLY ROUGH ALL NIGHTER MAKING COPIES OF THEIR BUSINESS
MAKING COPIES OFthe legs, at home depot they have a cutting station where you can measure and cut what you need (or ask a cute boy to help you) and wedge it under there...but it's gotta be tight enough she can't push it over. Plus you can bring the girls along, home depot is dog friendly

__________________
"My favorite color is green, green like newly cut grass. When it comes to green with envy, though, you can stick it up your @ss!" ~ Grammy

We had the same problems with the chis a couple of years ago, so we took the legs off of the couch. I'm not sure if your couch is the same way, but if you flip it you can actually unscrew each of the legs so the couch will


always kept Techdirt open and available to anyone. But in order to continue doing so, we need your support. We offer a variety of ways for our readers to support us, from direct donations to special subscriptions and cool merchandise — and every little bit helps. Thank you.

–The Techdirt Team

For years, we've talked about the importance of anti-SLAPP laws, and the shame that so far, they're on a state-by-state basis -- such that many states have no anti-SLAPP laws, and many others have incredibly weak anti-SLAPP laws. If you're unfamiliar with anti-SLAPP laws, they are laws that protect free speech in a very important way. In our overly litigious society, it's quite easy for someone to file a lawsuit against you just to bully you because they don'tin Seoul that Psy would pass Bieber on YouTube's most-watched list in about a month.

He thinks the secret of Psy's success lies in the speed at which the singer uploaded a sequel video on his official website, as well as footage of the making of his video and interviews, for users wanting to know more about him and "Gangnam Style".

"It comes like a total package at the end, so it just generated views," Hirai said, according to Yonhap news agency.

"I've been in this music business for 25 plus years and I've never seen anything like this and I've never imagined anything like this would come out of Asia. It's just unbelievable but it's overwhelming," he said.

Psy has also remained at number two on the Billboard Hot 100 music


      sample(1:6,20,replace=T), sep="_"))
dat2 <- cbind(df[sample(1:100,20),1:3],dat2)

dat3 <- data.frame(Type=rep('OP',20),
                   Val=paste(rep("OP", 20),
                             sample(1:6,20,replace=T), sep="_"))
dat3 <- cbind(df[sample(1:100,20),1:3],dat3)

df <- rbind(df, dat1, dat2, dat3)

Now, plotting the points having D_1,D_4 values for Type=="D".
df %>% filter(Val %in% c('D_1','D_4')) %>%
  ggplot(aes(X,Y,col=Val)) + geom_point() + geom_text(aes(label=ID))

Note: I have added IDs geom_text(aes(label=ID)) only for illustartion purposes.
To this, existing plot, I have to add remaining 92 points which do not have above two values or no values at all. I have tried adding additional points toMachine-Type Communication (MTC) is a promising and emerging technology to enable a ubiquitous computing environment towards the concept of “Internet of Things.” Potential MTC-based applications include smart metering, healthcare monitoring, remote security surveillance, intelligent transportation system, etc. These services and applications may stimulate the design and development of a new type of MTC device that may be seamlessly integrated into current and next generation mobile broadband networks such as LTE and LTE-Advanced.
The existing mobile broadband networks were designed to optimize performance mainly for human-type communications and thus are not generally designed or optimized to meet MTC related requirements. MTC specific design are being studied by Third Generation Partnership Project (3GPP) Radio Access Network (RAN) working groups (WGs) for specification support in Release-12 LTE specifications. The studies are focused


Maison Margiela Shirt Purple Variagated Stripe

This Classic fit shirt from Maison Margiela is crafted from cotton. It presents an all-over contrast stripe and a Décortiqué detail, turning the outline of a classic garment’s pocket into a statement feature. It is also designed with a double placket, disguising the button fastenings and showcasing empty button-holes for a new take.  url = "http://" + url;
       }
       if (youtube == true) {
          n = url.indexOf('&');
          if (n !== -1) {
             url = url.substring(0, n);
          }
          newUrl = url.replace("/watch?v=", "/embed/");
          url = newUrl;
       }
       if (youtubeShort == true) {


the net for Ottawa, the team would without question be in far worse shape on the league table. He’s not quite standing on his head the same way he did last year, but the Golden Glove winner is tied for second in the league with 27 saves and come up with numerous critical saves. The Rowdies will likely need to produce a few more quality chances and finishes than they have in recent weeks in order to get by Peiser.year playing in 47 games in total; only Son Heung-min and Harry Kane made more. Fernando Llorente, a dismal signing from Swansea City, made 31 appearances scoring just 5 times. Expensive flops Georges-Kévin N’Koudou and Vincent Janssen are still hanging around and need to be shipped out. There are just few places to start.

Everyone was dismissive of Rose and his comments last year about Tottenham’s recruitment and the club need to do better. Time is running out for these players to win trophies and they may leave to get that elsewhere. And then there is the manager. It won’t be long before Real Madrid or Manchester United are looking for a new manager and turn to Mauricio Pochettino.

This is the best Spurs side of a generation with some


cell substrate still valid; (ii) is there a new rationale that would warrant its continued use; and (iii) if there is a continuing need for karyology, is it unique to diploid cell cultures or does it need to be extended to all types of cell systems? The original rationale was that karyology provided evidence of the normal character of WI-38 cells and therefore supported its acceptability as a cell substrate for vaccine production. Karyology essentially has remained as a legacy of the intense debate that led to the acceptance of WI-38 cells. There is no new information over the past 30 years to suggest that there is a new rationale for instituting chromosomal analysis of cell substrates. If there were, however, it is difficult to imagine why ithave regained attention in materials science as nanocontainers for controlled release of different chemical agents including corrosion inhibitors, biocides, antifouling agents, drugs, etc. \[[@B7-polymers-10-00163],[@B8-polymers-10-00163],[@B9-polymers-10-00163],[@B10-polymers-10-00163],[@B11-polymers-10-00163],[@B12-polymers-10-00163]\].

Developing nanocontainers which have the ability to encapsulate desired active materials efficiently, and maintain them successfully in the inner cavity during long time periods, is the essential and critical approach in establishing new encapsulation system. Beyond that, a desired property of the envisaged containers is the immediate or prolonged release of encapsulated active material triggered by specific changes in the environment surrounding the container or directly in the container shell \[[@B13-polymers-10-00163]\]. HNTs can offer many benefits for introducing in polymer composites due to their characteristics of tubular nanostructure, high stability, excellent biocompatibility, low cost, and proper mechanical properties, which may replace the more expensive CNTs


used as received. Methenamine, used for guest loading, was purchased from Alfa Aesar (Ward Hill, MA, USA).

2.2. Sample Preparation {#sec2dot2-polymers-10-00163}
-----------------------

The modification of halloysite nanotubes was carried out through random copolymerization of the amphiphilic monomer with the acryloyl groups on halloysite nanotube surface. Details on the synthesis of grafted halloysite nanotubes and amphiphilic monomer are given in the [Supplementary Materials](#app1-polymers-10-00163){ref-type="app"}. The samples "HNTs-AM-AGC", "HNTs-AM-53%AGC" and "HNTs-53%AM-AGC" were prepared according to the feeding mass ratio "1:1:1, 1:1:0.53 and 1:0.53:1" respectively. The in situ synthesis procedure of halloysite nanocomposites was carried out via random copolymerization initiated by an initiator V50, by which the amphiphilic units were grafted onto the surface of halloysite. A schematic of the synthesized procedure is shown in [Scheme 3](#polymers-10-00163-sch003){ref-type="scheme"}.

2.3. Characterization {#sec2dot3-polymers-10-00163}
---------------------

The structure, amount of grafted groups, andselectivity of (stretched) transitions involving maximal orbital angular momentum transfer is a firm qualitative feature. Such large $\ell$-selectivity in one-neutron pickup at intermediate energy is shown in Fig. 2 of Ref. [@gad16p] and where, for a $^9$Be target, the reaction proceeds by the pickup of well-bound nucleons leaving the target residue in the continuum [@gad11]. Importantly, unlike the ($\alpha,d$) reaction, where the transfer vertex selects an np-pair with spin $S=1$, here there is no such restriction, allowing, for example, for the direct population of the $(\pi f_{7/2},\nu f_{7/2})^{(J=6^+)}$ final state. This difference is illustrated by the ($\alpha,d$) reaction to the mirror of that was found to populate the $(\pi f_{7/2},\nu
f_{7/2})^{(J=7^+)}$ configuration but not the corresponding $6^+$ state [@del76] or by the ($\alpha,d$) reaction to the neighboring Sc isotope


it individually for each list. The project may have as many as 240 description lists of three  different types.
I wanted to keep things flexible in case I had different ideas, but maybe I'm applying too much of an HTML/CSS mindset -- there I would use class attributes even if I had no specific plans to style things differently, just in case I wanted to do it later.

A:

The package enumitem offers the possibility of adapting the description environment and to define custom lists, e.g.
\documentclass{article}

\usepackage{enumitem}

% Define small caps description-like environment
\newlist{scdesc}{description}{1}
\setlist[scdesc]{font=\mdseries\scshape,noitemsep}

\begin{document}

\begin{description}
\item[Foo] explanation for foo
\item[Bar] explanation for baz
\item[Baz] explanation for baz
\end{description}

\begin{description}[font=\slshape]
\item[Foo] explanation for foo
\item[Bar] explanation for baz
\item[Baz] explanation for baz
\end{description}

\begin{description}[font=\mdseries\scshape]
\item[Foo] explanation for foo
\item[Bar] explanation for baz
\item[Baz] explanation for baz
\end{description}

\begin{scdesc}
\item[Foo] explanation for foo
\item[Bar] explanation for baz
\item[Baz] explanation for baz
\end{scdesc}

\end{document}

EDIT With the macro\SetEnumitemKey you can define a shorthand for a (more or less arbitrary) list of keys:
\documentclass{article}

\usepackage{enumitem}
\SetEnumitemKey{myclassA}{font=\slshape,noitemsep}
\SetEnumitemKey{myclassB}{font=\mdseries\scshape,noitemsep}

\begin{document}

\begin{description}[myclassA]
\item[Foo] explanation for foo
\item[Bar] explanation for bar
\item[Baz] explanation for baz
\end{description}

\begin{description}[myclassB]
\item[Foo] explanation for foo
\item[Bar] explanation for bar
\item[Baz] explanation for baz
\end{description}

\end{document}


           Decided:   August 18, 2005

Before WILKINSON, LUTTIG, and SHEDD, Circuit Judges.

Dismissed by unpublished per curiam opinion.

R. J. Keystone, Appellant Pro Se. Steven Andrew Witmer, OFFICE OF
THE ATTORNEY GENERAL OF VIRGINIA, Richmond, Virginia, for Appellee.

Unpublished opinions are not binding precedent in this circuit.
See Local Rule 36(c).
PER CURIAM:

             R. J. Keystone, a.k.a. Randall J. Keyes, a Virginia

prisoner, seeks to appeal the district court’s order granting the

Commonwealth’s motion to dismiss and denying relief on his petition

filed under 28 U.S.C. § 2254 (2000).            The order is not appealable

unless   a   circuit   Q:

Calculating the probability of a card being 'beaten'.

I'm trying to calculate the probability of a 'card' being beaten for a certain card game for a school project and require some assistance with my calculations.
So a given card can be beaten by cards of the same suite with higher value, or by cards of the trump suit (determined each round), what I want to calculate is for a given card, what is the probability of someone else drawing, and being able to play a card to beat it, where you play your cards around from player 1 to 4 and then the 'highest' card wins.
So for any card, there is some set of cards that can beat it, say N, and there is a set amount of draws, say


362 F.2d 328
WESTERN GEAR CORPORATION, Appellant,v.STATES MARINE LINES, INC., Appellee.
No. 20430.
United States Court of Appeals Ninth Circuit.
June 13, 1966.

1
M. Bayard Crutcher of Bogle, Gates, Dobrin, Wakefield & Long, Seattle, Wash., for appellant.

2
Donald S. Voorhees, of Riddell, Williams, Voorhees, Ivie & Bullitt, Seattle, Wash., for appellee.

3
Before HAMLEY AND JERTBERG, Circuit Judges, and THOMPSON, District Judge.

THOMPSON, District Judge:

4
This is an appeal from a summary judgment granted to States Marine Lines, Inc. upon the ground that the cause of action was barred by the applicable statute of limitations found in the Carriage of Goods by Sea Act [46 U.S.C.A. § 1303(6)].1 We affirm.

5
Appellant, Western Gear Corporation, manufactured certain Barcs (Barge, Amphibious Re-Supply Craft) for the United States Army. A Barc is a large fourwheeled, two-propellered cross between a truck and athe numbers of reads mapped to each gene. Then the RPKM of each gene was calculated based on the length of the gene and the numbers of reads mapped to the gene. Differentially expressed genes were selected using the DEGSeq R package (1.12.0) with the corrected *p* ≤ 0.005 (adjusted by the Benjamini & Hochberg method) and \|Log~2~(fold-change)\| \> 1.5. The gene-function annotation was conducted based on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) database. The significantly enriched KEGG pathways were selected using KOBAS (2.0) software with *q* \< 0.05.

Analysis of the secondary metabolism gene clusters
--------------------------------------------------

The secondary metabolism gene clusters in *V. dahliae* were predicted by the Secondary Metabolite Unknown Region Finder (SMURF; Khaldi et al., [@B12]). The orthologous genes in *Verticillium alfalfae* were


based on GO and KEGG pathways annotation revealed that the 823 downregulated genes were involved in various cellular processes, such as biosynthesis of secondary metabolism, amino acid metabolism, and pyruvate metabolism (Figure [9](#F9){ref-type="fig"}). Transcriptomic data were confirmed by qRT-PCR to determine the expression levels of several genes (two bZIP genes VDAG_08640 and VDAG_08676, a Crz1 homology gene VDAG_03208, a melanin biosynthesis related gene VDAG_00190, a pyruvate kinase gene VDAG_01206). The results showed that qRT-PCR results and transcriptomic data were well correlated (Figure [S4](#SM4){ref-type="supplementary-material"}).

![**Subcellular localization of VdMcm1**. Confocal microscopy of *Cp-Mcm1-GFP* (*VdMcm1-GFP* fusion, containing native promoter and coding sequence of VdMcm1 without stop codon and GFP fragment, was introduced into the *VdMcm1* deletion mutant) conidia and hyphae, which were harvested from liquid CM. The fluorescence was mainly localized in(≥4 cysteine residues) properties (Table [S2](#SM7){ref-type="supplementary-material"}).

Hundreds of putative target genes of *VdMcm1* were identified by comparative transcriptomic analysis between the wild-type strain and Δ*VdMcm1-5* mutant. Remarkably, dozens of downstream genes regulated by VdMcm1 were also identified as putative target genes of *Vta2* (Tran et al., [@B42]). Some phenotypes of the *VdMcm1* deletion mutant were similar to the *Vta2* deletion mutant. First of all, the growth rate of these two mutants was significantly reduced. Secondly, both mutants displayed drastic reduction of conidiation. Thirdly, the virulence of both mutants was reduced. However, the mechanism for the reduced virulence was different between these two mutants. Conidia of *VdMcm1* deletion mutants failed to attach onto the roots while the *Vta2* deletion mutants could adhere and germinate on the roots but not colonize


genes involved in this process were downregulated in *VdMcm1* deletion mutant, such as melanin biosynthesis genes VDAG_00189 and VDAG_03665, a fad binding domain-containing protein VDAG_01149, a cytochrome p450 VDAG_03650, and a bZIP transcription factor VDAG_08640 (Duressa et al., [@B7]; Xiong et al., [@B51]). Furthermore, a hydrophobin-encoding gene VDAG_02273 reported to be involved in microsclerotia formation (Klimes and Dobinson, [@B14]; Klimes et al., [@B13]) showed reduced transcript level in Δ*VdMcm1-5*. The results indicated that *VdMcm1* controls microsclerotia formation by regulating the downstream genes that are involved in microsclerotia development.

In summary, the results displayed in this study demonstrate that *VdMcm1* plays important roles in fungal development, secondary metabolism, and virulence in plant pathogenic fungus *V. dahliae*. The results provide evidence that *VdMcm1* plays pleiotropic roles through regulating hundreds of downstreamthe wild-type strain showed one different band (the length of *VdMcm1*) whereas the ectopic mutants contained two bands: one for the geneticin resistance cassette, one for *VdMcm1*. **(D)** Semiquantitative RT-PCR was performed to validate the deletion and reintroduction of *VdMcm1*. **(E)** Confirmation of the *VdMcm1* deletion mutant by Southern blot with a *VdMcm1* probe. Genomic DNA of wild-type strain and *VdMcm1* deletion mutant were digested with *Kpn I*.

######

Click here for additional data file.

######

**Expression analysis of genes related to melanin biosynthesis**. Calculation the transcript levels of five melanin biosynthesis genes with qRT-PCR. The β-tubulin gene was used as a reference gene for the expression analyses. The error bars represent standard deviations. The experiments were performed in triplicate.

######

Click here for additional data file.

######

**Scanning electron microscopy of


            refused[r] = (errcode, errmsg)
        return refused

class MailmanProxy(PureProxy):
    def process_message(self, peer, mailfrom, rcpttos, data):
        from cStringIO import StringIO
        from Mailman import Utils
        from Mailman import Message
        from Mailman import MailList
        # If the message is to a Mailman mailing list, then we'll invoke the
        # Mailman script directly, without going through the real smtpd.
        # Otherwise we'll forward   classname = classname[lastdot+1:]
    else:
        import __main__ as mod
    class_ = getattr(mod, classname)
    proxy = class_((options.localhost, options.localport),
                   (options.remotehost, options.remoteport))
    try:
        asyncore.loop()
    except KeyboardInterrupt:
        pass


know about Islam or Buddhism or Hinduism or atheism? How do bank workers recognize counterfeits?

Some Possible Objections

1) “See to it that no one takes you captive through hollow and deceptive philosophy…” (Col 2:8) It’s a warning against false philosophy. The cure is good philosophy, not ‘no philosophy’.

2) Only the Holy Spirit could touch a person’s heart to believe, not arguments. Apologetics is not a competitor of God’s work of illumination, but a way in which the Holy Spirit could use in opening peoples’ eyes. It’s like the ministry of transportation, bringing someone to a ‘place’ where they can hear the gospel.

3) Faith like a child? Jesus is talking about humility and dependence of a child, not the ignorance of a toddler.

4) The gospel is the foolishness of God…their character rather than the tasks they perform, “for each man provides his own character, whereas chance assigns him tasks.”

This urge to treat the enslaved as equal human beings runs counter to the horrifying picture of Roman slavery that Seneca paints (and condemns) elsewhere in the letter, wherein masters routinely brutalize their slaves to satisfy their own passions. Seneca responds with dismay and revulsion to the silencing, beating, and sexual exploitation of slaves, saying that Romans treat slaves as beasts of burden and are “exceedingly arrogant, exceedingly cruel, exceedingly abusive” toward them.

It does, I admit, initially seem extraordinary that an elite Roman man can see such humanity in the enslaved. It is simply not an argument one often finds in Greco-Roman texts. And it is one inescapably indebted


own head. They spoke at dinner-parties but under torture were silent.

The slave’s prioritizing of his master’s life and bodily integrity above his own undermines the supposedly egalitarian view elsewhere in the letter. The Stoic master’s humane treatment of his slaves, in the end, is less a reflection of their intrinsic human worth than his own cultured and cosmopolitan humanitas. The loyal slave’s chief value is to furnish evidence for the Stoic credentials of his master. Such fidelity attests to the master’s ordered rule over himself as well as his household.

Seneca’s “loyal slaves” readily call to mind the Lost Cause, with its idealization of plantation life and oft-repeated stories of slaves guarding the home front during the Civil War. Stephen Elliott, who served as an Episcopal bishop in thean artist (artifex), can sculpt to reflect his own virtues. It is such virtues that are front-and-center as early as the opening sentence of the letter, where Seneca tells Lucilius that his treatment of slaves is a testimony to his prudentia (“wisdom”) and eruditio (“learning”).

Seneca is ultimately less interested in the condition of the slave than that of the master, with whom he readily identifies; Seneca, unlike his fellow Stoic Epictetus (a freedman), had no personal experience of being enslaved. The only truly problematic slavery in the letter is the interior, moral one the master may be experiencing.

While the letter has much to say about the liberation of the master’s soul, it has nothing to say about the liberation of the slave’s body, a consideration that Seneca’s Stoic


notion of freedom as an internal state renders moot. It is not surprising that one prominent Southern defender of slavery, James Henley Thornwell, in an 1850 sermon entitled “On the Rights and Duties of Masters” (delivered for “the benefit and instruction of the coloured population”), approvingly quotes Seneca’s letter — alongside passages of Pythagoras, Plato, Cicero, and Claudian. Yoking the Stoic definition of freedom (that “slavery to sin is true slavery”) to a New Testament passage, Colossians 3, that was long used to justify slavery, he writes:

It is precisely the assertion of this freedom — this dominion of rectitude — this supremacy of right, which the Apostle enjoins upon slaves — when he exhorts them to obey their masters in singleness of heart as unto Christ […] Toreport. This is our most comprehensive streaming dataset yet, and there is, quite simply, nothing else like it out there. Knowing the size of streaming revenues, or the global subscriber counts of music services is useful, but it isn’t enough. Nor even, is knowing country level streaming revenue figures. So, we built a global market shares model that breaks out subscription revenues (trade and retail), subscribers, and subscription market shares for more than 30 music services at country level, across 30 countries and regions. You want to know how much subscription revenue Spotify is generating in Canada? How many subscribers Apple Music has in Germany? How much subscription revenue QQ Music is generating China? This is the report for you. Here are some highlights:

At the end of 2016


to extend their reach to the west may view EU regulators as an opportunity to prize open the market for them.

The Pendulum Swing Of Disruption

When a new technology disrupts a traditional incumbent, it normally does so by being 3 things to the end user:

Cheaper/free

Quicker

More convenient

Napster, YouTube, Amazon, Uber, Netflix, all of these companies have done exactly this. Because they most often build market share and presence using external funding, such companies turn existing economics upside down with loss leading tactics. The result is that audiences switch in their millions and incumbents are left in tatters. Any old business that relies on scarcity economics will be swept away.

Take Uber’s impact on taxi drivers across the world. In the UK, a black cab driver will spend 5 years riding aroundon the 31st December. It was an impressive end to an impressive year for streaming, but does it mark a change in the music industry, a fundamental change in the way in which streaming works for the music industry’s numerous stakeholders?

Streaming Has Piqued Investors’ Interest

The streaming market was always going to hit the 100 million subscriber mark sometime around now, but by closing out the year with the milestone it was ahead of schedule. This was not however entirely surprising as the previous 12 months had witnessed a succession of achievements and new records. Not least of which was the major labels registering a 10% growth in overall revenue in Q2, driven by a 52% increase in streaming revenue. This, coupled with Spotify and Apple’s continual out doing


of each other with subscriber growth figures, Spotify’s impending IPO and Vevo’s $500 million financing round, have triggered a level of interest in the music business from financial institutions not seen in well over a decade. The recorded music business looks like it might finally be starting the long, slow recovery from its generation-long recession.

Spotify Continues To Set The Pace

Spotify has consistently led the streaming charge and despite a continually changing competitive marketplace it has held determinedly onto pole position since it first acquired it. Even more impressively, it has also maintained market share. According to data from MIDiA’s Music Streamer Tracker, in Q2 2015 Spotify’s share of global music subscribers was 42%, H2 15 41%, H1 16 44%, H2 16 43%. Not bad for a service facingan end to the grow-at-all-costs For the music industry, the stakes are even higher, as an under-achieving Spotify IPO would create a crisis in confidence in the entire streaming market.

Among our music predictions for 2017 are Spotify’s IPO and the subsequent start of a new generation of experiential streaming services, Tidal selling (probably to Apple) while Spotify closes out the year with around 55 million subscribers to Apple Music’s 30 million.

Facebook beat estimates with its latest earnings but announced that ad revenues would likely slow in 2017 as the digital ad market feels the pinch of advertiser budgets lagging the shift in user behaviour. Facebook’s stock fell by 7% but it already has Plan B in motion: to become a media company. Facebook delayed this move as long


pursuing. Here are a few companies that could help Spotify on this path:

Soundcloud: arguably the biggest artist-to-fan platform on the planet, Soundcloud could form a talent discovery function for Spotify. Spotify could use its Echo Nest intelligence to identify which acts are most likely to break through and use its curated playlists to break them on Spotify. Also artist platforms like BandPage and BandLab could play a similar role.

Indie labels: Many indie labels will struggle with cash flow due to streaming replacing sales, which means many will be looking to sell. My money is on Spotify buying a number of decent sized indies. This will demonstrate its ability to extend its value chain footprint, and therefore margins (which is important for Wall Street). It could also ‘do aINTRODUCTION
============

Total hip arthroplasty (THA) is a safe and reliable surgical procedure for the treatment of painful primary or secondary osteoarthritis of the hip. However, THA also has intra- and postoperative complications. A frustrating intraoperative complication for every surgeon is when the trial femoral head dissociates from the taper and migrates into the pelvis. Making a decision regarding how to deal with such a situation is challenging for every surgeon. As described by other authors, the trial femoral head probably cannot be directly retrieved from the pelvis *via*only a hip incision \[[@R1]-[@R4]\].

We here report on the intraoperative dislocation of the femoral trial head into the iliac muscle during a primary THA.

PATIENT AND CASE DESCRIPTION:
=============================

We report on a 71-year old female patient, admitted to our clinic for elective THA with


housing in Milwaukee.”

The MHD Childhood Lead Poisoning Prevention Program has traditionally promoted community screening and testing of children for lead poisoning and conducted inspections of residential housing units for lead-based paint hazards. Since 1997, more than 16,000 housing units have been made lead safe through MHD efforts. The current HUD funding will allow the MHD to provide approximately 700 additional lead-safe housing units primarily for low-income families and through the rehabilitation of foreclosed properties.

“In cities with older housing stock such as Milwaukee, lead poisoning remains a significant environmental health threat to children residing in or visiting properties with lead-based paint hazards,” said Commissioner of Health Bevan K. Baker. “Lead poisoning in young children has been linked to learning and behavioral problems that can affect a person’s ability toat low speeds is possible. This technique can also incorporate other techniques, such as varying the threshold for detecting imbalance based on the type of rotor. Hence, this technology has begun to be employed in a wide variety of centrifuges. With this method, a simple construction can be used to detect with great accuracy imbalances exceeding the allowable amount according to design specifications.


Measurement of seizure freedom in adjunctive therapy studies in refractory partial epilepsy: the levetiracetam experience.
To assess the advantages and disadvantages of six methodologies used in calculating seizure freedom rates in placebo-controlled, adjunctive therapy trials of new antiepileptic drugs (AEDs) in partial epilepsy, and two methodologies for long-term follow-up studies. Data from levetiracetam trials were used to illustrate the impact of different methodologies on seizure freedom rates. Seizure-freedom data for several new AEDs were identified from the published medical literature using MEDLINE and from a recent comprehensive textbook. Most randomized, placebo-controlled add-on clinical trials of new AEDs contain little or no information about seizure freedom. Importantly, the methodology used can profoundly affect results when calculating seizure-free rates. Seizure freedom data should be reported as well as the methodology used.The minimum duration for assessing seizure freedom should be the entire stable dose period in short-term trials and at least six months for long-term follow-up studies. It is proposed that the seizure freedom rates be calculated and reported with at least two different methodologies, one that considers patients withdrawing from treatment without having had a seizure as successes, and one that considers the same patients as failures. For an effective and well-tolerated AED, seizure freedom rates will be consistent across the two methodologies. Seizure freedom is the ultimate goal of AED therapy and should be reported for all clinical trials. Methodological differences among the few clinical studies reporting seizure freedom rates make it difficult to compare results across trials. Improved reporting of methodologies and seizure-free rates is warranted.


a security ring or band joined to the upper portion of the cap along a line of weakening. When the cap is unthreaded from the bottle, the band separates along the line of weakening and remains on the bottle. To insure that the band does not come off under the worst tolerance conditions, the band includes a plurality of inwardly-extending, thin plastic tabs which engage the bottle.Latest News

13OctMotion Graphics Video Production in Scotland

Make something that stands out and hits your message!

These ads are fun! We have been working with Aberdeenshire Council in Scotland over the past few months to develop their Get About campaign targeting how residents get around the City of Aberdeen and the Shire. It is part of their ongoing messaging to help change behaviours and bring about a “greener’ population utilising multiple transportation options when going on “”utility” journeys- that’s anything other than leisure.

We’d love to know what you think- they combine motion graphics with simple messaging for the targeted population. They are all currently airing on the STV network in the Aberdeenshire area- have you seen them? You can see our "Walking" Ad below and the other current ads can


VeChain Financial Executive Report Vol. 8

Transparency, Fairness, Openness

We are excited to present the eighth VeChain Foundation Financial Executive Report. This financial report covers the period from May 2019 through to July 2019.

During this period, VeChain partnered with San Marino Innovation and DNV GL to adopt the VeChainThor Blockchain in San Marino Republic to strive to become the first carbon neutral country. On July 16, 2019, the VeChainThor blockchain recorded the day with the highest number transaction clauses since the mainnet launch — over 1.1 million transaction clauses with over 35 million VTHOs burned. We are making further progress on solving real-world economic problems and targeting a broader user base with the VeChain blockchain technology.

As always, we sincerely welcome the community to hold us to the commitment of transparency,a great benefit from reloading for the .460 Weatherby Magnum. Reloading the .460 Weatherby Magnum is no more difficult than reloading any other belted magnum cartridges. The reloader has a wide variety of components, bullets and powders available.

Among bullet manufacturers Barnes, Hornady and Lyman provide reloading data in their manuals for the .460 Weatherby Magnum. Powder manufacturers Accurate Arms, Hodgdon and Norma have also provide reloading data for the cartridge.

Bullets

The .460 Weatherby Magnum accepts  bullets. There are a large variety of bullets manufactured which are suited for the .460 Weatherby. Bullets weighing between  are acceptable although the cartridge performs best with bullets weighing between . The  bullets are optimized for use with the .45-70 Government cartridge. Such bullets are used with reduced loads. All major


 bullet launched at .

See also
 Weatherby Magnum
 List of rifle cartridges
 Table of handgun and rifle cartridges
 11 mm caliber
 .45 Caliber Rifle Cartridges
 .378 Weatherby Magnum
 .416 Weatherby Magnum
 .30-378 Weatherby Magnum
 .338-378 Weatherby Magnum

References
 Weatherby Inc.
 460 Weatherby Magnum - Official Page
 Weatherby Mark V Rifle - Official Page
 460 WEATHERBY MAGNUM Cartridge statistics from AccurateReloading.com
 A-Square 460 Weatherby Magnum Triad ammunition from A-Square.com

Footnotes

Category:Magnum rifle cartridges
Category:Pistol and rifle cartridges
Category:Weatherby Magnum rifle cartridgesApolipoprotein mRNA in liver and intestine of rats is affected by dietary beet fiber or cholestyramine.
Rats were fed a cholesterol-free diet with no added fiber (fiber-free) or with 15 g/100 g beet fiber or 5 g/100 g cholestyramine for 14 d. Final plasma total cholesterol concentrations were significantly lower in rats fed beet fiber than in those fed fiber-free or cholestyramine diets. This difference was due mainly to lower HDL cholesterol concentrations. The group fed beet fiber also tended (P < 0.1) to have lower apolipoprotein A-I concentration in plasma. Northern blot analysis revealed that the relative concentrations of jejunal apolipoprotein A-I and A-IV mRNA were the same in all groups, whereas ileal apolipoprotein A-I and A-IV mRNA levels were significantly lower in rats fed beet fiber or


cholestyramine than in those fed the fiber-free diet. Hepatic apolipoprotein E mRNA concentrations were the same in all groups, but apolipoprotein A-I mRNA levels were significantly lower in rats fed beet fiber than in those fed the other diets. Apolipoprotein A-IV mRNA tended (P < 0.1) to be lower in rats fed the beet fiber diet. These data suggest that the hypocholesterolemic effect of dietary beet fiber is associated with diminished expression of the hepatic apolipoprotein A-I gene.[@R27] and their families\' quality of life,[@R27] [@R28] and to society.[@R24] [@R26] [@R29] [@R30] Therefore, early detection and interventions are of major importance. In order to investigate the relationship between adolescent musculoskeletal pain and mental health problems in young adulthood we linked the Norwegian Patient Registry[@R31] section on specialised mental healthcare with a population-based study, the Norwegian Arctic Adolescents Health Study.[@R32]

The aim of this study was to investigate whether multisite musculoskeletal pain in adolescents was associated with mental health problems in young adulthood in an unselected community sample. Second, to determine the importance of musculoskeletal pain in relation to later mental healthcare use and mental health disorders, when adjusting for adolescent psychosocial factors. Third, we wanted to explore differences in the potential association between adolescent musculoskeletal pain and


  1.05 (0.99 to 1.09)^p=0.053^
  *Model 4---life stressors:*                        3703   R^2^=0.046
   School-related stress                                    1.18 (1.12 to 1.24)^p\<0.001^
   Adverse life events                                      1.14 (1.08 to 1.20)^p\<0.001^
  *Model 5---mental health:*at her with those button eyes. She suddenly realized it and turned back, looked into his eyes and he shut down looking into his hand as if he wasn’t.

That smile she had when he pulled his eyes down with modesty remained unexplained.

She looked forward again and concentrated into her peanuts. That salty taste he had on his lips while she was having it and he tried to wet his lips by his own tongue and granted himself an unsatisfied temporary pleasure

He was still trying to draw her picture which was incomplete I guess as he was anxious. His heart being engraved by her portrait without quenching his thirst for love. He wanted to touch her perfectly god carved shoulders which were just in front of his eyes but


New Zealand at the Champions Trophy.

“We anticipate Tom being available soon and we had no intention of playing two overseas players in this year’s competition,” Lewis explained. “If they were both available at the same time we would look at it but it’s not what we were looking to do.”

Durham lost a badly rain-affected game at Second XI Championship game at Derbyshire this week but back-to-back Twenty20 games against Warwickshire at South Northumberland on Monday should offer valuable game-time to those who need it.

“The second team didn’t get as much cricket in as we’d hoped against Derbyshire but there’s no doubt that going straight from Chesterfield (where Durham played a County Championship game which ran until the Thursday) into our first T20 game (at home to Lancashire on(p less than 0.02); pulmonary vascular resistance increased by 400% (p less than 0.01). Arterial hypoxemia developed (p less than 0.02) in association with an increase in the low ventilation-perfusion ratio index but without a significant increase in intrapulmonary shunt. Thromboxane B2 levels increased 10-fold. Infusion of the carrier substance for dazmegrel after 2 h of GBS infusion produced no change in any variables. In contrast, infusion of the drug resulted in the return to pre-GBS infusion baseline values for both pulmonary arterial pressure and pulmonary vascular resistance. However, no improvement in arterial pO2 or in the low ventilation-perfusion ratio index occurred. Both pulmonary vascular resistance and pulmonary arterial pressure remained normal for 0.5 h after dazmegrel administration despite continued GBS infusion. Thromboxane B2 levels were decreased 30


mixed genotype cultures \[[@pcbi.1004848.ref004], [@pcbi.1004848.ref007], [@pcbi.1004848.ref008], [@pcbi.1004848.ref013], [@pcbi.1004848.ref016], [@pcbi.1004848.ref017]\].

Such mixed genotype cultures are expected to be common in microbes, which often live in highly diverse and dense communities where many different genotypes meet and compete \[[@pcbi.1004848.ref005], [@pcbi.1004848.ref018]--[@pcbi.1004848.ref021]\]. What then maintains cooperative phenotypes in microbes? One explanation is the spontaneous formation of clonal patches within microbial communities by cell division (also see \[[@pcbi.1004848.ref022]\]). As cells divide and grow in dense and nutrient-limited conditions, bottlenecks occur that cause genotypes to segregate into large clonal patches. The formation of these patches in initially diverse microbial groups is an empirically well-established phenomenon, having been observed in numerous microbial species including bacteria, yeast and amoeba, and different experimental conditions including agar plates and flow cells \[[@pcbi.1004848.ref023]--[@pcbi.1004848.ref032]\]. Theoretical work suggests that this patch formationThis changes when we consider strong evolutionary competition with a low initial proportion of secretors. Importantly, **Q** strains succeed against competing non-secretors where constitutive secretors fail. Quorum sensing then enables cooperation in highly competitive environments where non-secretors would otherwise dominate. What is the cause of the advantage to **Q** strains over **C** strains under these conditions? Regulating secretion means that **Q** strains invest less in secretion overall than constitutive secretors. But in the supplement we reduce the investment of constitutive secretors to remove this difference and show that they still lose where **Q** strains win ([S1 Fig](#pcbi.1004848.s001){ref-type="supplementary-material"}). The key to success of **Q** then is the timing of secretion (in [S2 Fig](#pcbi.1004848.s002){ref-type="supplementary-material"} an artificial time-delay strategy demonstrates this). Quorum sensing allows a newly colonizing strain to compete against


ability to infer cell density and perhaps diffusion rates. The second issue is that quorum sensing cells must resist competition from non-secreting cheater mutants. Here we show that, under conditions of strong competition, these two issues combine to provide a critical benefit to quorum sensing that is not simply due to the assessment of cell density. With nutrient limitation and high numbers of competing genotypes, the key benefit to quorum sensing in our system comes from the ability to delay public good secretion and grow quickly when first in a new environment. This allows quorum sensing cells to outgrow constitutive secretors while keeping up with fast growing non-secretors until clonal patches have formed in a microbial group. In particular, the delay in cooperative secretion in quorum sensing genotypes100 simulations is computed, where the cells of genotype *x* inoculated initially are replaced with *y* cells and a mono-culture of the majority genotype is simulated. The invasion index *I*~*x*\ →\ *y*~ of a rare mutant *x* into a metapopulation with majority genotype *y* was calculated for each of the 100 replicates as $$I_{x\rightarrow y} = \frac{w_{x}}{\left\langle w_{y} \right\rangle}.$$ Under the assumptions of our model, we conclude that *x* can invade a metapopulation of *y* when *I*~*x*\ →\ *y*~ \> 1.

Statistical analysis {#sec013}
--------------------

Simulation results are from 100 independent replicates. Fitness data is non-normal and often bimodal distributed where the bimodality differs between simulations with different initial frequencies and/or initial cell densities meaning it is difficult to apply standard statistics. In some figures we show box plots and test


\right.$$

Segregation with respect to a focal cell, *s*(*c*~*i*~), was calculated as the mean product of the *g* and *m* functions for every cell in its neighbourhood: $$s\left( c_{i} \right) = \frac{1}{N}\sum\limits_{j = 1}^{N}{g\left( c_{j} \right)}$$ Finally, we define the segregation index *σ* for the entire cell group as the mean value of *s*(*c*~*i*~) across the population of cells: $$\sigma = \frac{1}{M}\sum\limits_{i = 1}^{M}s\left( c_{i} \right)$$

The segregation index measures the degree to which co-localised cells are clonally related to each other. Relatedness in social evolution is defined as the probability that two individuals are more genetically similar than the population average. The segregation index is equal to a form of the relatedness coefficient from social evolution theory under the following assumptions: (i) A cell expressing the cooperative phenotype equallynot limited to design, installation, and modification of processing and packaging lines; modifications of ammonia refrigeration systems; and design and installation of material handling systems.

Manage environmental compliance efforts of the company. These efforts are primarily in the areas of wastewater management and OSHA PSM / EPA RMP for ammonia refrigeration systems.

Qualifications:

B.S.C.E. or equivalent from an ABET accredited program. At least 5 years of structural experience. Candidates possessing a professional license or working towards licensure are preferred.

NOTES:

Employer will assist with relocation costs.

About Pictsweet

Pictsweet is a 4th generation, family owned company established in 1945. We are vertically integrated with our own agricultural division and manufacturing plants which differentiate us vs. our competitors. The Pictsweet Farms brand currently is in a strong #3 share position in the $4B+ frozen vegetable category.


a knife apparently wielded by a left-handed person who cut himself in the hand during the stabbing.
On the afternoon of March 2, 1972, Gary Crawley, appellant and appellant's stepbrother, Marc Setencich, were arrested and charged with Kroupa's murder. At the time of the arrest, appellant had a knife wound on his left hand. Thereafter, Crawley and Setencich entered pleas of *346 guilty as accessories after the fact to the murder; appellant entered a plea of not guilty to the murder charge, and the cause proceeded to jury trial.
At the trial, the prosecutor called Gary Crawley and Marc Setencich as witnesses for the People. In answer to the prosecutor's preliminary questions, Crawley stated that he was 22 years of age, a high school graduate, right-handed and addicted to heroinand seconal; he said that he knew Kroupa, that he had purchased drugs from the decedent's girl friend, Doris Ihlenfeldt, and that he pled guilty to being an accessory after the fact in the murder. Then, the prosecutor asked the witness if he had gone to Kroupa's house on the evening of March 1, 1972. Crawley refused to answer on the ground that the question tended to incriminate him. The court, however, ruled that Crawley did not have the right to assert the Fifth Amendment privilege against self-incrimination because he had pled guilty to complicity in the crime; he told the witness that if he did not answer the question he would be in contempt of court. Later, out of the presence of the jury, Crawley's lawyer explained


statement imputed to but not admitted by him. Nor was the opportunity to cross-examine the law enforcement officers adequate to redress this denial of the essential right secured by the Confrontation Clause. Indeed, their testimony enhanced the danger that the jury would treat the Solicitor's questioning of Loyd and Loyd's refusal to answer as proving the truth of Loyd's alleged confession. But since their evidence tended to show only that Loyd made the confession, cross-examination of them as to its genuineness could not substitute for cross-examination of Loyd to test the truth of the statement itself. [Citations.]
"Hence, effective confrontation of Loyd was possible only if Loyd affirmed the statement as his." (Douglas v. Alabama, supra, 380 U.S. 415, *351 419-420 [13 L.Ed.2d 934, 937-938, 85 S.Ct. 1074, 1077];of the probability of another trial, we shall consider the Attorney General's argument on the merits.
Section 1230 of the Evidence Code makes admissible into evidence a declarant's statement against his own penal interest if the declarant is unavailable as a witness; under section 240 of the Evidence Code, a witness is unavailable when he asserts the privilege against self-incrimination. (People v. Smith, 13 Cal. App.3d 897, 902 [91 Cal. Rptr. 786, 52 A.L.R.3d 875].). (5) While the United States Supreme Court has indicated that under some circumstances the admission into evidence of a declaration against penal interest, where the declarant is unavailable as a witness, does not offend the confrontation clause of the United States Constitution (Dutton v. Evans, supra, 400 U.S. 74, 89 [27 L.Ed.2d 213, 227,


A Virtual Universe (VU) is a computer-based simulated world or environment; other terms for VU's include metaverses, “3-D Internet” and Virtual World, and VU will be understood to represent any of these environments. Users inhabit and traverse a VU, and interact with other VU users through the use of an avatar, a graphical representation of the user often taking the form of a cartoon-like human though any two or three dimensional graphic image or rendering may be utilized. In order to participate within or inhabit a VU a user creates an agent which functions as the user's account, and upon which the user builds an avatar tied to an inventory of assets the user owns in the VU and associated with the agent.
Many VU's are represented using threeQ:

Simplify development environment setup

Everytime new people start working on our project, they need to setup development environment on their computer Windows OS running on it. This contains:

Java
Eclipse as IDE
Tomcat
Maven
MySQL
... and maybe some other tools

It takes time (because of download and install) and some people getting problems (for example because of missungerstanding setup guide)
Is it possible to simplify or maybe automate such development environment setups? My idea is to create kind of bundle and deliver it to developers. If some software need still to be installed it's also ok.
I found this question here How to automate development environment setup? but:

I would like to find solution without using virtual machine if it somehow possible
this question is from 2009. Maybe the things changed in last 7 years.

Thank you in advance
UPDATE
Just found


and on-line. To date, CSF represents the largest scale implementation of a psychology based training intervention in the history of the discipline. In January, 2011, a special issue of the flagship journal of the American Psychological Association, The American Psychologist,[2] was devoted to a description of CSF. Since its inception, CSF has impacted hundreds of thousands of soldiers, and it continues to be refined and expanded.

Another important application of positive psychology over the past decade has been in using its principles to improve the lives of military families, particularly children. The Military Child Coalition (MCEC), a non-profit organization dedicated to serving military children and improving the quality of their lives, has adopted positive psychology as the conceptual framework for its extensive educational and training programs. Positive psychologists includingcalculated quickly over minutes, hours, days, and weeks.

Enhancements to the Actical system were made without altering its size. The compact, lightweight, and noninvasive design of the device allows subjects to continue to go about their activities of daily living without noticing they are wearing it. Actical also has a waterproof enclosure which is especially useful for certain activities such as swimming.

Please note the ActiCal comes on its own. A waist bands, wrist straps need to be purchased separately.

Accelerometer Details

Range

0.05 G to 2 G

Bandwidth

.035 Hz to 3.5 Hz

Resolution

100 counts or 0.02 G (at 1 G peak)

Sampling rate

32 Hz

Sampling modes

Raw + steps

Epoch: 1, 2, 5, 15, 30, 60 sec
Epoch + steps: 1, 2, 5, 15, 30, 60 sec

Enviromental Atributes

Moisture protection*

Waterproof IEC60529 IPX7 1 meter for 30 min

Storage/transportation temperature range

-4 to


140°F (-20 to 60°C) to 95% humidity

Operating temperature range

*It is not recommended that any Actical/ActiWatches are worn in a Shower/Bath/Jacuzzi/Swimming Pool etc. This is the same for any watch as the heat/steam causes expansion and creates the potential for leaks. See this post from GQ Magazine for more details.influence in society, but his outspoken criticism of President Cristina Kirchner couldn’t stop her from imposing socially liberal measures that are anathema to the church, from gay marriage and adoption to free contraceptives for all.

“In our ecclesiastical region there are priests who don’t baptize the children of single mothers because they weren’t conceived in the sanctity of marriage,” Bergoglio told his priests. “These are today’s hypocrites. Those who clericalize the Church. Those who separate the people of God from salvation. And this poor girl who, rather than returning the child to sender, had the courage to carry it into the world, must wander from parish to parish so that it’s baptized!”

Bergoglio compared this concept of Catholicism, “this Church of ‘come inside so we make decisions and announcements between


Cristina Fernandez, took over the Argentina’s government. His outspoken criticism couldn’t prevent Argentina from becoming the Latin American country to legalize gay marriage, or stop Fernandez from promoting free contraception and artificial insemination.

His church had no say when the Argentine Supreme Court expanded access to legal abortions in rape cases, and when Bergoglio argued that gay adoptions discriminate against children, Fernandez compared his tone to “medieval times and the Inquisition.”

This kind of demonization is unfair, says Rubin, who obtained an extremely rare interview of Bergoglio for his biography, the “The Jesuit.”

“Is Bergoglio a progressive — a liberation theologist even? No. He’s no third-world priest. Does he criticize the International Monetary Fund, and neoliberalism? Yes. Does he spend a great deal of time in the slums? Yes,” Rubin said.

Bergoglioterror, including a young woman who was 5-months’ pregnant before she was kidnapped and killed in 1977. The De la Cuadra family appealed to the leader of the Jesuits in Rome, who urged Bergoglio to help them; Bergoglio then assigned a monsignor to the case. Months passed before the monsignor came back with a written note from a colonel: It revealed that the woman had given birth in captivity to a girl who was given to a family “too important” for the adoption to be reversed.

Despite this written evidence in a case he was personally involved with, Bergoglio testified in 2010 that he didn’t know about any stolen babies until well after the dictatorship was over.

“Bergoglio has a very cowardly attitude when it comes to something so terrible


2*a - 12. Let o be (8/a)/((-1)/9). What are the prime factors of (-3)/o - (-22)/8?
3
Let c(y) = 3*y - 6 + y + 5*y - y**2. Suppose -1 = p - 8. List the prime factors of c(p).
2
Let r(j) be the third derivative of -4*j**4 - 2*j**2. Let f be r(-2). What are the prime factors of 4/10 + f/20?
2, 5
Let v(g) = g**3 - 3*g + 3. Let x be v(2). Let z = x + -1. Suppose 0 = -z*n - n + 60. List the prime factors of n.
2, 3
Let h be 12 + (1 - (1 - 4)). What are the prime factors of ((-24)/h)/((-1)/30)?
3, 5
Let s(v) = -5*v + 4*v**2 + v + 3 + 3*v - 3*v**2. What are the prime-2*p, w*p - u = 52. What are the prime factors of p?
2, 7
Suppose o + 2*o - 129 = 0. What are the prime factors of o?
43
Let z(g) = g. Let p be z(0). Let s be p/(-4) + (-2)/(-2). What are the prime factors of 2*((-63)/(-6) - s)?
19
Let f = 10 + -6. Suppose f*c - 8*c = -108. List the prime factors of c.
3
Suppose 13*v - 14*v = -177. List the prime factors of v.
3, 59
Suppose -r + 4*r - 30 = 0. Let u = r + -28. List the prime factors of (-2)/9 + (-436)/u.
2, 3
Let p = -74 - -21. Let x = p - -97. List the prime factors of x.
2, 11
List the prime factors of (16/(-20))/((-1)/60).
2, 3
Let o = -9


Melba,

The following changes need to be made to the attached GTC for this product:

1.   Section 1:  Delete subsection (iv) and revise subsection (iii) to read
as follows:

(iii) unless it has notified the other party in writing to the contrary, it
is a domestic corporation (as such term is defined in Section 7701 of the
United States Internal Revenue Code of 1986, as amended);

2.   Section 2:  Before the paragraph beginning " Each payment will be
made...", the following paragraph should be inserted:

All payments under this Transaction shall be made without any deduction or
withholding for or on account of any Tax unless such deduction or withholding
is required by any applicable law, as modified by the practice of any
relevant governmental revenue authority,Boudjellal happy with Wilkinson signing

19 May 2009 11:27:00

Toulon president Mourad Boudjellal insists the recruitment of injury-prone England star Jonny Wilkinson from Newcastle is a gamble worth taking.
Since dropping the goal that won England the World Cup in 2003, Wilkinson has been plagued by injury problems and he has not played since dislocating a kneecap on Newcastle duty at Gloucester last September.
"If it doesn't work out, we'll put it down to a moment of folly," said Boudjellal, who has bankrolled Toulon for the past few years after making his fortune from the comic-book business.
He added: "But who hasn't fantasised about a rugby player like Wilkinson, a great among the greats, a player who is out of this world?"
Wilkinson has signed a two-year contract with Toulon and his sojourn to


a and b. (**d**) Detail of infected zone showing the co-localization of *Micromonospora* and *Rhizobium* in the host cells. The white circle in 6c shows the area where image (**d**) was captured. Bars: 60 µm (**a**--**c**); 20 µm (**d**). dpi, days post inoculation; C, cortex; BZ, bacteroid zone.

For *Medicago*, *Micromonospora* was localized across the nodule and infected cells were visible in all but the meristematic zone (Fig. [7a](#Fig7){ref-type="fig"}). As in *Trifolium* nodules, in some cases, both bacteria occupied the same host cells (Figs. [7c,d](#Fig7){ref-type="fig"}). Figure [7a,b](#Fig7){ref-type="fig"} show the distribution of the bacteria captured by the corresponding fluorescence channels (green for *Micromonospora* and red for *Sinorhizobium*). A close up of the nodular tissue permitted a clear visualization of *Micromonospora* ML01-*gfp* cells (Fig. [7e](#Fig7){ref-type="fig"}).Figure 7*L*ongitudinal sections of a *Medicago* 20 dpi nodule showing the distribution ofplayed for the trial court an audio-

video recording from a camera mounted in the front of the first officer’s patrol car

(the “dash-cam recording”). The first officer’s initial interaction with Dougherty on

the road was captured only on the audio portion of the dash-cam recording, and some

of Dougherty’s verbal responses to the officer are difficult to hear on it. The police

encounter with Dougherty from the point when he stepped in front of the first

officer’s patrol car until he was subdued and arrested was captured on both the video

and audio portion of the dash-cam recording.

      Following the first officer’s testimony and the playing of the dash-cam

recording, the State rested. Dougherty elected not to testify or call any defense

witnesses.

      After hearing the


   for the purpose of investigating suspected criminal activity; and
      third-tier encounters are actual or de facto arrests and, accordingly, must
      be supported by probable cause.

(Citation and footnote omitted.) Thomas v. State, 301 Ga. App. 198, 200 (1) (687

SE2d 203) (2009). “A police officer is not discharging his lawful duty when he arrests

an individual without reasonable or probable cause,”or when he conducts a brief

investigatory detention of an individual “without a particularized and objective basis

for suspecting criminal activity.” (Citations and punctuation omitted.) In the Interest

of J. T., 239 Ga. App. 756, 759 (521 SE2d 862) (1999). See Curtis v. State, 285 Ga.

App. 298, 300 (1) (a) (645 SE2d 705) (2007); Wynn v. State, 236 Ga. App. 98,in the

area, and Dougherty at most exhibited “furtive” behavior when initially approached

by the officer. Dougherty further maintains that because the first officer initially

detained him without reasonable suspicion of any criminal activity, the officer was

not acting in the lawful discharge of his official duties from that point onward,

rendering unlawful the officers’ subsequent efforts to handcuff and arrest him.

Consequently, Dougherty contends that he was entitled to resist his detention “from

the beginning” and to continue resisting throughout the police encounter, including

when both officers sought to handcuff and arrest him. We are unpersuaded.

      As an initial matter, we conclude that there was evidence supporting the trial

court’s determination that there was some interaction between Dougherty and the first

officer on the road, albeit very brief, before the officer escalated


necessary, some basis from which the court can

determine that the detention was not arbitrary or harassing.” (Citation and

punctuation omitted.) Gonzalez v. State, 334 Ga. App. 706, 711 (2) (780 SE2d 383)

(2015). “[T]he determination of reasonable suspicion must be based on commonsense

judgments and inferences about human behavior” rather than on scientific certainty.

Illinois v. Wardlow, 528 U.S. 119, 125 (120 SCt 673, 145 LE2d 570) (2000).

      Pretermitting whether the first officer had reasonable suspicion based on the

information supplied by the 911 dispatcher about the attempted car break-ins in the

area, we conclude that there was evidence that the officer had reasonable suspicion,

based on his initial observation and interaction with Dougherty, to believe that

Dougherty was a pedestrian under the influence and to detain him on that ground.of ZFC. If $\alpha_0,\alpha_1$ are the first two ordinals such that $L_{\alpha_0}$ and $L_{\alpha_1}$ are models of ZFC, then $L_{\alpha_1}$ is a model of ZFC in which there is a transitive model of ZFC, namely $L_{\alpha_0}$, and every transitive model of ZFC has rank $\alpha_0$ and is therefore bounded in size by $|V_{\alpha_0}|$.

A:

In a comment to François's answer, I point out that the least $\alpha$ such that $L_\alpha$ is a model of $\mathsf{ZFC}$ is countable. In what follows, "model" means "transitive model of $\mathsf{ZFC}$."
If $M$ is transitive, then $L^M=L_\beta\models\mathsf{ZFC}$ for $\beta=\mathsf{ORD}\cap M$, so the least height of a model is countable. Moreover, any model $M$ proves that there is a bijection between each level of its cumulative hierarchy, and one of its ordinals, so if $M$ has height


Choice functions on sets and classes. In Sets and classes (on the work by Paul Bernays), pp. 217–255. Studies in Logic and the Foundations of Math., Vol. 84, North-Holland, Amsterdam, 1976. MR0424566 (54 #12525).

          new Person { FirstName = "Abe", LastName = "Lincoln" },
            new Person { FirstName = "Groucho", LastName = "Marks" },
            new Person { FirstName = "Carl", LastName = "Marks" },
        };

        listView.ItemTemplate = new DataTemplate(typeof(TextCell));
        listView.ItemTemplate.SetBinding(TextCell.TextProperty, "FirstName");
        listView.ItemSelected += async (sender, e) => {
            await DisplayAlert ("Tapped!", e.SelectedItem + " was tapped.", "OK", "");


decrease in the proportion and number of splenic cDC1s, whereas the cDC2s were unaffected. As hypothesized with the pDCs, we believe that this is because the *Rosa-26* promoter does not significantly increase the level of Zeb2 expression in this subset. Once again, we observed that only targeting one allele had limited effects on either subset ([Fig. 1, G and H](#fig1){ref-type="fig"}; and Fig. S3). Interestingly, the increased expression of Zeb2 in CD11c^+^ cells led to the presence of a new XCR1^+^SIRPα^+^ population of cDCs in the spleen ([Fig. 1, G and H](#fig1){ref-type="fig"}; and Fig. S3). To our knowledge, the presence of such a population has not previously been reported. These XCR1^+^SIRPα^+^ (double positive \[DP\]) cDCs also expressed intermediate levels of CD24, a marker typically associated with cDC1s ([Fig. 1demonstrate that Zeb2 functions during cDC2 development, we next crossed the recently described *late-Cd11c^Cre^* mouse ([@bib50]), in which the CRE is not active during pre-cDC development but only once the pre-cDCs mature into cDCs ([@bib50]), with *Zeb2^fl/fl^* and *Zeb2-R26^Tg/Tg^* mice. Analysis of these mice revealed that the loss of Zeb2 late in cDC development does not affect the prevalence of the cDC subsets ([Fig. 4 C](#fig4){ref-type="fig"}). Additionally, the effects of overexpressing Zeb2 were minimized in these mice ([Fig. 4 C](#fig4){ref-type="fig"}). Thus, we can conclude that Zeb2 functions to maintain the balance between cDC1s and cDC2s during development.

![**Zeb2 regulates cDC subset development.** (A and B) Representative FACS plots showing identification of pre-cDC subsets and proportions of pre-cDC subsets in the BM (A) and spleen (B) of Zeb2^+/+^, Zeb2^−/−^, and


mM CaCl~2~, and 0.2% Triton X-100). DNA fragment size (150--500 bp) was confirmed after chromatin preparation in a 1.2% agarose gel. The fragmented chromatin was incubated with 10 µg FLAG-M2 (F3165; Sigma-Aldrich) antibody overnight followed by a pull-down assay using A/G-conjugated agarose beads (EMD Millipore). DNA was purified with an iPure kit (Diagenode), and the quality was measured using a 2100 Bioanalyzer system with a DNA kit (High Sensitivity; Agilent Technologies). Real-time qPCR was performed on a Zeb-predicted binding site identified in the *Id2* promoter with the following primers: 5′-TACCTGACAAAGAGCTTCCC-3′ and 5′-TTACATACACTGCCCTTGGT-3′ (primer pair A) and 5′-ATGTGGCTGCATCTAGGAA-3′ and 5′-GGGAAGCTCTTTGTCAGGTA-3′ (primer pair B). Primers in the coding sequence of the *GAPDH* gene were used as a control of unspecific binding with the following primers: 5′-TTGAGCTAGGACTGGATAAGCAGG-3′ and 5′-AGTCCGTATTTATAGGAACCCGG-3′. The percentageRiot Fest Denver 2013 day one: Photos of the people and culture

Riot Fest Denver kicked off on Sept. 21 in the Colorado town of Byers, bringing a healthy mix of punks, indie-rockers and everything in between. With a stacked lineup that included the newly reunited Replacements, Best Coast, Guided by Voices, Iggy and the Stooges, AFI, Alkaline Trio, the crowd was diverse — to say the least. Leather jackets, jean jackets, metal studs, teenagers, middle-agers, patches, green, red, blue hair, flannel shirts, no shirts — we caught it all at Riot Fest Denver. But billed as a “sideshow” too, there was quite a bit to take in, including wrestling, a Ferris wheel and people wearing only pink inner-tubes. Take a look at our photos below of the mosh


Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

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Scenes of the crowds at day one of Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

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Scenes of the crowds at day one of Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

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Scenes of the crowds at day one of Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

59 of 80

Scenes of the crowds at day one of Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

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Scenes of the crowds at day one of Riot Fest Denver on Sept. 21, 2013. Photos by Dylan Langille, heyreverb.com.

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Scenes of the crowds at day one of Riot Festor sitting-room, with a handsome open fireplace furnished with an iron fire-basket. A tiny window pierced in the outer wall looked out on the street. There was a vase of tulips standing in it. At the end of the room was a very large window with an arched top, but this was glazed with frosted glass. Gently looked down at the well-brushed carpet which covered almost the entire floor, then stooped for a closer inspection. There were two small square marks near the outer edge of the carpet, just by the door, very clearly defined and about thirteen inches apart. He glanced absently round at the furniture, shrugged and closed the door carefully again.

There were five men in the study, plus a sheeted figure that a few hours


then his eyebrows lifted the merest shade. One of the newcomers was Susan.

But Susan was on her own. Also, she seemed to be in a little 'state' about something. She ignored the waitress who wanted to fit her in a large table and with a toss of her sweeping blonde locks made for a smaller one near Gently's own.

'But we are keeping that table for two of our regulars, madam . . .'

'There's no "reserved" notice on it, is there?'

'It is their usual table, madam . . .'

'A pot of tea and some cakes.'

The waitress shrugged and moved away. Gently indulged in a smile. Someone had let Susan down, he thought, she's all dressed up with nowhere to go . . . is Mr Leaming the culprit? Heyou heard nothing?'

'I should not have heard . . . once, everything went black and I thought I would fall. Then I came to myself again, and I knew I must do something . . . something to stop people thinking that it was him.'

'You had no doubt in your mind then that Fisher was the murderer?'

'. . . no, I had no doubt.'

'Have you had any doubt since that time?'

'. . . no.'

'Where did you next see him?'

'He was waiting in the bedroom when I got back. He asked me where I had been . . . when I told him that my father was killed he pretended to be surprised.'

'And it was he who suggested establishing alibis?'

'Oh yes . . . he said that I might


Go in there and find that key – and don't come out till you've got it!' He turned back to Gently. 'All right – so if it isn't there you've made a point – but you haven't proved your case or anything like it. Meantime I'm giving the Coroner's Court the OK and this case is going in on its merits. I'm satisfied with what I've got. If you want more, you'd better go after it – only you won't be getting any help from me. Is that clear?'

Gently felt sadly in his pocket and brought out an empty bag. 'Quite clear,' he said, screwing it into a ball, 'quite clear.'

#

## CHAPTER FOURTEEN

THE CORONER'S COURT sat on the day following and returned on Nicholas Huysmann a verdict ofget in bad with the police!'

'Whoa!' interrupted Gently pacifically, 'it's no use getting out of breath, my dear. Somebody had to tell them about that suitcase and where to find it . . .'

'It wasn't me! I didn't know nothing about it.'

'Then who did – who else knew about it?'

'How the hell should I know? Perhaps they saw him carting it around and got the idea it was something valuable . . .'

'Who told you he was given to carting it around?'

'Nobody told me—!'

'And how did they know where he lodged – that he was out – that for some reason he'd left it in his room?'

'They could've watched him, couldn't they?'

'They aren't professionals, Frenchy.'

'They're sneaking little swine, that's what they are!'

She flung herself at the bed and


assuming a custom though they had it not.

Louey gestured comfortably towards the gateway. 'Rivals of mine . . . but they don't have a licence! Shall we stroll through?'

Gently nodded drippingly. 'I want to see the place. It's where Streifer dropped the man who was tailing him on Friday.'

'Which shows he knew his job, Inspector. Isn't this where you would come to shake off a tail?'

'I can't say I've had much experience . . .'

They passed under the flaunting portal with its electric jewellery. The close-packed attractions within wore a rueful look, unsupported by the crowds. Larger and more expensive pieces were frankly at a standstill – the Caterpillar had postponed its gallop, the Glee Cars their jaunting – while the smaller roundabouts and rides were operating atthe Dyke somewhere.

'What would she have got up for?'

There were guffaws and tittering, and glances at a sheepish-looking Ted Thatcher. He grinned at Gently and turned on the others in mock indignation.

'Don't know what yew're all lookin at me for! Ennaone'd think I made a habit of strange women.'

'Well don'tch'?' shouted someone and there was a ripple of laughter.

Gently said: 'You were dancing with her last night.'

'W'yes . . . but that i'nt the same as what this dirta-minded lot seem to think!'

'She could have arranged to see you later.'

Ted gave him a wink. 'Yew're nearla as bad as they are, an tha's pretta bad!'

'Did she, or didn't she?'

'She di'nt then – though I woon't say she ha'nt got a mind tew. But that wa'nt noth'n definite, an'