different cycles (100, 500, 1 000, 2 000, and 3 000) in all groups and yield loads of groups C and D were measured and analyzed. The displacement of group A was significantly smaller than that of group B at the cycles of 100, 500, and 1 000 ( P<0.05); the displacement of group C was significantly smaller than that of group D at every cycle ( P<0.05). Additionally, the yield load of group C was significantly higher than that of group D ( t=4.816, P=0.001). Pre-implantation of high-intensity suture into tendon grafts play an important role in the prevention of postoperative graft creep and relaxation in ACL reconstruction.generally driven by an external power source, such as an electric motor, while the other is driven from the first. An inlet port and an outlet port are formed by removal of some portion of the material along the region of overlap between the cylindrical chamber bores. Net flow is transverse to the plane of the rotor shafts: the pumped material moves around the perimeter of the rotors from inlet to outlet, drawn into the blower as the interleaved lobes move from the center of the cavity toward the inlet port, opening a void; carried around the chamber in alternate “gulps” of volume between two lobes of a rotor in a cylinder, released to the outlet port by the lifting of the leading lobe of each successive gulp


back to the inlet side due to differential pressure Δp) between properly-shaped straight lobes can be substantially constant, however, to the extent that all gaps can be made uniform and invariant. Developments in manufacturing technology by the 1930s included the ability, at reasonable cost, to make gear teeth and compressor lobes that advance along the axes of rotation following a helical path. This lead to Roots-type blowers with effectively constant displaced volume rather than discrete pulses, such as those disclosed by Hallet, U.S. Pat. No. 2,014,932. Such blowers have displayed pulsating leakback, however, so that the net delivered flow remains non-constant.the phase-locked loop locking dynamics are similar.
In the prior art, the core digital loop filter is implemented with a proportional and integral path that mimics an analog loop filter which can be represented in the Z domain with the following transfer function:
      Y              (      z      )        =            [              α        +


1996.   NODSI was initiated primarily to serve the container needs of
Evergreen, a company specializing in the transportation of oceangoing cargo in
a fully containerized atmosphere. NODSI serviced Evergreen exclusively until
2002, when it also contracted with Mitsui O.S.K. for similar services. Williams
testified that Evergreen did not request that NODSI be set up in a specific
location. Williams further testified that he selected the location for the Chef
Yard because of the hard land, and did not consider access to a waterway. The
Terminal Yard was acquired through a lease with the Board of Commissioners
for the Port of New Orleans. Williams testified that access to a waterway was
not a consideration in the selection of the Terminal Yard site.
      Zepeda’s son, a terminal supervisor for NODSI, testified in                            No. 11-60057

      “The Supreme Court has cautioned that we must ‘take an expansive view
of the extended coverage’ of the LHWCA.” Sisson, 131 F.3d at 557 (quoting Ne.
Marine Terminal Co. v. Caputo, 432 U.S. 249, 268 (1977)) (emphasis added).
“The Act should be liberally construed in favor of injured workers, ‘in
conformance with its purpose, and in a way that avoids harsh and incongruous
results.’” Winchester, 632 F.2d at 515 (quoting Voris v. Eikel, 346 U.S. 328, 333
(1953)). There is a “presumption of coverage.” Id. at 508.
      “For a claimant to be eligible for


                                  7
   Case: 11-60057       Document: 00511932873          Page: 8     Date Filed: 07/25/2012

                                       No. 11-60057

requirement reduces the number of workers walking in and out of coverage and
promotes uniformity.” Winchester, 632 F.2d at 516. “If the situs determination
is supportedby substantial evidence on the record as a whole, it will not be set
aside by this court.” Id. at 515.
       In this case, the ALJ relied on several items of evidence in reaching his
determination that the Chef Yard is a maritime situs. The ALJ found that,
regardless of NODSI’s employees’ awareness of such, some of the Evergreen
containers repaired by NODSI were used for marine transportation and were
offloaded at the Port of New Orleans. NODSI initially only serviced Evergreen
containers, and was required, pursuant to Evergreen’s labor contract, to hire
unionized maritime workers, including Zepeda.                      Accordingly, the ALJ
determined that the functional nexus requirement was satisfied


on
periodically, are essential to the loading and unloading process.”).6

       6
          We note that the dissent’s interpretation of the LHWCA, according to which the repair
of shipping containers used in maritime transport is not maritime activity within the purview
of the statute, would create a circuit split. See Alfaro v. Commissioner, 349 F.3d 225, 229 (5th
Cir. 2003) (“We are always chary to create a circuit split.”). According to our precedents,
circuit splits should be avoided unless persuasive reasons exists for creating them. See United
States v. Adam, 296 F.3d 327, 332 (5th Cir. 2002); Carranza-De Salinas v. Gonzales, 477 F.3d
200, 208 (5th Cir. 2000). In our view, the dissent’s attempt to distinguish a carpenter’s
construction of scaffolding, to bejob site that was
used to load or unload vessels; and the Chef Yard, Zepeda’s primary workplace
while employed by NODSI and the only work site at issue, is not connected to or
even surrounded by areas used to load or unload vessels, and, critically, is not
used to repair or maintain equipment that is used to load or unload ships.
Despite these facts, the majority still concludes that NODSI can be held liable
under a statute that should apply to him only if Zepeda played an “integral or
essential part of loading or unloading a vessel,” Chesapeake & Ohio Ry. Co. v.
Schwalb, 493 U.S. 40, 45 (1989), and was injured at a maritime situs, 33 U.S.C.
§ 903(a). Because this conclusion is contrary to law and common sense, I
respectfully dissent.


“adjoining area” that is “customarily used . . . in loading [or]
unloading.” Even under the framework of our already-expansive precedents, the
answer to this question is, quite clearly, no.
      Our cases break this “other adjoining area” question into two inquiries: (1)
whether the situs in question is sufficiently close to the waterfront (geographic
nexus) (2) and whether it has a functional nexus to maritime activity. See
Hudson, 555 F.3d at 432. The ALJ defined the relevant “area” as the Chef Yard
itself. NODSI concedes that, under our caselaw, the Chef Yard satisfies the
geographic nexus prong. The relevant inquiry is therefore whether the work
done at the Chef Yard, storing and repairing cargo containers, is customarily
part of the loading or unloading process.
      “Loading and unloading”act that its exceptionally expansive

       3
         The majority, understandably, relies heavily on the deferential standard of review,
but its approach exemplifies a troubling pattern that has developed in our case law. Rather
than analyzing whether there is substantial evidence that the Chef Yard is “used in loading
or unloading,” the majority merely concludes that the AJL’s situs determination is only a
minor expansion of what has previously been accepted as a maritime situs, and therefore
approves the expansion. The problem with this approach is that, as the majority essentially
concedes, it results in an ever-shifting baseline for evaluating the reasonableness of the BRB’s
decisions. So long as each case is only incrementally more expansive than the last, it is bound
to be


of the pier to
perform its core longshoring operations. Id.
       Zepeda, on the contrary, was not similarly a part of loading or unloading
operations because his work was not something that a loading company would
have to arrange or commission in order to load ships. The relevant question is
whether the work at issue is within the purview of what a loading company
would have to accomplish in order to successfully carry out its shiploading work.
Because a loading company must provide for (whether with its own employees
or independent contractors)6 the repair of its piers and loading equipment, but
is not responsible for packaging its customers’ cargo, Carroll is readily
distinguishable. Zepeda was not “an integral part” of shiploading or any other
maritime project and therefore is not a maritime employee       Employers should be able to ascertain their potential liability under the
LHWCA, and the majority’s opinion will make that more difficult than ever. In
this vein, it is important to note that NODSI consulted two separate insurance
brokers, who both advised that the company did not need LHWCA insurance.
Industry expectations cannot be controlling of our decisions, but we have
previously stated that “Congress intended that liability should be imposed only
where the employer had real or constructive notice of the likelihood of coverage.”
Carroll, 650 F.2d at 757.
         I respectfully dissent.


g. Is j a prime number?
False
Let z(x) = x**3 - 6*x**2 + 6*x - 8. Let l be z(6). Suppose l = -5*s + 93. Is s prime?
True
Is (2/(-6))/((-6)/17874) prime?
False
Suppose -4*t - r - 88 = 0, 2*r + 9 = 1. Let x be (-1 - 0)/(3/t). Let o(m) = 14*m - 1. Is o(x) prime?
True
Let q = -186 + 306. Suppose 5*u - 128 = -483. Let m = u + q. Is m composite?
True
Let o(r) = 10*r**2 + 8. Let u be o(6). Let s = 197 + u. Is s composite?
True
Suppose -5*m = -6*m + 20. Suppose 3*n + z - 5*z = 28, -4*n + m = -z. Suppose 84 = n*a - 0*a. Is a prime?
False
Suppose -4*r = 4 - 12. IsWho decides that a majority of Australians are racist? Or that majority of Australia is racist? Who decides that India and Kazakhastan are not racist? Who decides that the degree of racism in Australia is higher than the degree of racism in India? Did anybody do a statistical analysis that Indians were being targeted only because they are Indians and not because they usually are alone and thus vulnerable or physically not that capable of fighting back? Did anybody prove this conclusively and decidedly? The only thing I hear is another-attack-on-a-defenseless-Indian-who-never-swats-a-fly… so are only Indians being attacked and there is no other crime in Australia?

Perhaps, you have an agenda here of trying to dampen the fighting spirit of Indians against the racial attacks by trying to highlight the


prob of picking 4 a.
22/91
Two letters picked without replacement from wgpndqq. What is prob of picking 1 p and 1 w?
1/21
Calculate prob of picking 1 y and 3 u when four letters picked without replacement from {r: 3, b: 1, x: 2, m: 3, u: 3, y: 2}.
2/1001
Two letters picked without replacement from bxevvyqeeeyqqb. Give prob of picking 1 q and 1 y.
6/91
Calculate prob of picking 3 e when three letters picked without replacement from eeeeee.
1
Calculate prob of picking 2 d, 1 v, and 1 c when four letters picked without replacement from {v: 3, c: 1, o: 5, s: 1, f: 3, d: 5}.
1/102
Four letters picked without replacement from {l: 2, a: 3, t: 1, r: 1, n: 3}. What is prob of picking 1 r and<!DOCTYPE html>

    <meta http-equiv="refresh" content="0;URL=../../../../libc/constant.IPPROTO_TRUNK1.html">

Redirecting to ../../../../libc/constant.IPPROTO_TRUNK1.html...


the opportunity to see what others in the same field are doing and how they are handling certain issues from their end — and you will get to practice some of this yourself. In addition, by the very nature of your involvement, you will be looked upon to some extent as a leader within that organization. Further, your will develop some important contacts that can help in your career in a very personal way.

3. At work, don’t worry about which techniques you are using. Apply the best that you can. However, above all else, seize the moment to build strong and open personal relationships with those that you engage with. Work towards a reputation of integrity – for being credible, honest, and transparent so that people will trust line: 3,
          column: 13,
        },
      ],
    },
    // https://github.com/typescript-eslint/typescript-eslint/issues/453
    {
      code: `
let bar: number = 1;
bar! + 1;
      `,
      output: `
let bar: number = 1;
bar + 1;
      `,
      errors: [
        {
          messageId: 'unnecessaryAssertion',
          line: 3,
        },


    errors: [
        {
          messageId: 'unnecessaryAssertion',
          line: 3,
        },
      ],
    },
    {
      code: `
declare function nonNull(s: string | null);
let s: string | null = null;
nonNull(s!);
      `,
      output: `
declare function nonNull(s: string | null);
let s: string | null = null;
nonNull(s);
      `,
      errors: [
        {
       of all heat-related diseases, and can cause death or serious disabilities.

It happens quickly when you ignore the symptoms of heat exhaustion, and your body is unable to cool down.

Quite simply, "It's a medical emergency," said Lawrence Armstrong, professor of exercise and environmental physiology at the University of Connecticut, and author of "Exertional Heat Illnesses."

Normally, your body floats around 98.6 degrees. But it rises to upwards of 103 if you're out in the sun — and especially if you're exercising in the heat. Your body simply can't dissipate all of its heat into the environment, so it starts storing the heat. All that warmth in your body is too much for your organs, which will start malfunctioning, and your body will lose its ability to sweat.

Many people will start


Author Affiliations: Departments of Pathology (Drs Timms and Horwitz and Messrs Wechsler and Kirkwood), Psychiatry (Drs Dorschner and Tsuang), and Genome Sciences (Drs Girirajan and Eichler and Mr Baker), and Division of Medical Genetics, Department of Medicine (Dr Korvatska), University of Washington School of Medicine, and Veterans Affairs Puget Sound Health Care System (Drs Dorschner and Tsuang), Seattle; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland (Drs Choi and Roche); and Departments of Biochemistry and Molecular Biology and Anthropology, The Pennsylvania State University, State College (Dr Girirajan).

ABSTRACT

Importance Schizophrenia is a complex genetic disorder demonstrating considerable heritability. Genetic studies have implicated many different genes and pathways, but much of the genetic liability remains unaccounted for. Investigation of genetic forms of schizophrenia will lead to8329 controls,23 several common copy number polymorphisms were identified; however, no rare CNVs (ie, observed in <8 of 8329 controls) were detected in any affected individuals in a pedigree. Further, no previously reported pathogenic large rare CNVs were identified.7,24 Therefore, we conclude that rare CNVs are not responsible for schizophrenia in these families.

EXOME SEQUENCING

Exome sequencing yielded an average mapped 2.48 Gb per sample; within coding regions, there was an average of 44 reads/nucleotide, with 87% of exonic nucleotides covered by 5 or more reads (eTable 3 and eTable 4). An average of 42 738 variants (42 050 SNPs and 688 indels) were seen per individual, of which 14 851 (14 779 SNPs and 73 indels) were in coding regions (eTable 5).

To identify disease-causing mutations, we filtered for protein-altering


We did not detect pathogenic CNVs in these families, as has been reported to occur de novo in sporadic cases of schizophrenia.7,8,11- 13 One possible explanation is that large rare CNVs confer risk for a more severe form of the disease (childhood onset or with associated comorbid intellectual disability), limiting reproductive fitness and subsequent familial transmission.

Frameshift mutation (occurring in cis with missense substitution) of GRM5 was present in pedigree 2 and found to reduce binding to the scaffolding protein tamalin, thereby increasing the internalization of its product, mGluR5, on agonist stimulation.

Glutamate is the major excitatory neurotransmitter in mammalian brains. Activation of mGluR5 enhances NMDA receptor signaling,25 so its disruption is consistent with the “NMDA glutamate receptor hypofunction hypothesis” of schizophrenia.33GRM5 does map near a translocation that segregates withequipment or
specific uniforms for any school activity, nor can we require you or
your family to pay security deposits or make donations in order to
participate in the program. All donations are strictly voluntary and
greatly appreciated as we work to support our schools and programs!2

Links to an e-commerce business

"PTA does not endorse, warrant or recommend any of these products. PTA will receive a small percentage of every sale. If you decide to purchase any products, we thank you."

All printed publications “Not printed at CUSD expense”

Products mentioned in a newsletter or publication

PTAs
may not endorse products or services or encourage members to purchase
them. If using the name of a business or organization that supports your
school or PTA, print a disclaimer such as:

“The mention of any business or service in this publication does


your
 * decision by deleting the provisions above and replace them with the notice
 * and other provisions required by the GPL or the LGPL. If you do not delete
 * the provisions above, a recipient may use your version of this file under
 * the terms of any one of the MPL, the GPL or the LGPL.
 *
 * ***** END LICENSE BLOCK ***** */

ace.define('ace/mode/javascript', ['require', 'exports', 'module' , 'ace/lib/oop', 'ace/mode/text', 'ace/tokenizer', 'ace/mode/javascript_highlight_rules', 'ace/mode/matching_brace_outdent', 'ace/range', 'ace/worker/worker_client', 'ace/mode/behaviour/cstyle', 'ace/mode/folding/cstyle'], function(require, exports, module) {
"use strict";

var oop = require("../lib/oop");
var TextMode = require("./text").Mode;
var Tokenizer = require("../tokenizer").Tokenizer;
var JavaScriptHighlightRules = require("./javascript_highlight_rules").JavaScriptHighlightRules;
var MatchingBraceOutdent = require("./matching_brace_outdent").MatchingBraceOutdent;
var Range = require("../range").Range;
var WorkerClient = require("../worker/worker_client").WorkerClient;
var CstyleBehaviour = require("./behaviour/cstyle").CstyleBehaviour;
var CStyleFoldMode = require("./folding/cstyle").FoldMode;

var Mode = function() {
    this.$tokenizer = new Tokenizer(new JavaScriptHighlightRules().getRules());
    this.$outdent =     ],
                regex : "(:)(\\s*)(function)(\\s*)(\\()",
                next: "function_arguments"
            }, {
                token : "constant.language.boolean",
                regex : /(?:true|false)\b/
            }, {
                token : "keyword",


 next: "start"
            }
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        "regex_character_class": [
            {
                token: "regexp.keyword.operator",
                regex: "\\\\(?:u[\\da-fA-F]{4}|x[\\da-fA-F]{2}|.)"
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                regex: "]",
      "comment" : [
            {
                token : "comment", // closing comment
                regex : ".*?\\*\\/",
                merge : true,
                next : "start"
            }, {
                token : "comment", // comment spanning whole


Lesser General Public License Version 2.1 or later (the "LGPL"),
 * in which case the provisions of the GPL or the LGPL are applicable instead
 * of those above. If you wish to allow use of your version of this file only
 * under the terms of either the GPL or the LGPL, and not to allow others to
 * use your version of this file under the terms of the MPL, indicate your
 * decision by deleting the provisions above and replace them with the notice
 * and other provisions required by the GPL or the LGPL. If you do not delete
 * the provisions above, a recipient may use your version of this file under
 * the terms of any one of the MPL, the GPL          if (rightChar == ')') {
                var matching = session.$findOpeningBracket(')', {column: cursor.column + 1, row: cursor.row});
                if (matching !== null) {
                    return {
                        text: '',


         && this.foldingStopMarker
                && this.foldingStopMarker.test(line))
            return "end";
        return "";
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    this.getFoldWidgetRange = function(session, foldStyle, row) {
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    this.indentationBlock = function(session, row, column) {
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            endRow = row;
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        if (endRow > startRow) {
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    this.openingBracketBlock = function(session, bracket, row, column) {
        var start = {row: row, column: column + 1};


* the License. You may obtain a copy of the License at
 * http://www.mozilla.org/MPL/
 *
 * Software distributed under the License is distributed on an "AS IS" basis,
 * WITHOUT WARRANTY OF ANY KIND, either express or implied. See the License
 * for the specific language governing rights and limitations under the
 * License.
 *
 * The Original Code is Ajax.org Code Editor (ACE).
 *
 * The Initial Developer of the Original Code is
 * Ajax.org B.V.
 * Portions created by the Initial Developer are Copyright (C) 2010
 * the Initial Developer. All Rights Reserved.
 *
 * Contributor(s):
 *      Fabian Jakobs <fabian AT ajax DOT org>
 *
 * Alternatively, the contents of this file may be used under the terms of
 * eitherthe GNU General Public License Version 2 or later (the "GPL"), or
 * the GNU Lesser General Public License Version 2.1 or later (the "LGPL"),
 * in which case the provisions of the GPL or the LGPL are applicable instead
 * of those above. If you wish to allow use of your version of this file only
 * under the terms of either the GPL or the LGPL, and not to allow others to
 * use your version of this file under the terms of the MPL, indicate your
 * decision by deleting the provisions above and replace them with the notice
 * and other provisions required by the GPL or the LGPL. If you do not delete
 * the provisions above, a recipient may use your version


   token : "comment", // multi line comment
            merge : true,
            regex : "\\/\\*",
            next : "media_comment"
        }, {
            token: "paren.lparen",
            regex: "\\{",
            next:  "media_ruleset"
        },{
            token: "string",
      pressure was measured using a mercury sphygmomanometer three times, and the average of the second and third measurements was used. Demographic data including age (at assessment), gender, level of education, ethnicity, and lifestyle factors (including cigarette smoking, alcohol intake, and physical inactivity) were obtained by questionnaires as described previously \[[@pone.0135681.ref018]\]. Obesity was defined as a body mass index (BMI) (body weight \[in kg\] divided by square of body height \[m\]) ≥30). In addition to BMI, waist circumference and waist-hip ratio were also assessed for each participant (as these may be better indicators of central obesity which is more prevalent in Asian populations). Plasma glucose concentrations were determined by the glucose oxidase method on a Beckman Glucose Analyzer II (Beckman Instruments, Fullerton, CA, USA). The intra- and inter-assay coefficients


{#sec014}
=======

Demographic and baseline characteristics, allele frequencies, and LD structure {#sec015}
------------------------------------------------------------------------------

[Table 1](#pone.0135681.t001){ref-type="table"} shows the basic clinical characteristics of the study participants at baseline and follow-up. A total of 984 participants (767 from the Chinese Han population) were included in the Phase I study, and 522 participants were enrolled in Phase II (i.e. the present study). The mean follow-up period was 5.7 years, and the mean age of the study population at Phase I was 49.5 years with a mean BMI of 25.5 kg/m^2^. Among all participants, 77.9% were Chinese, 65.2% had hypertension, and 9.9% were obese. Of the 984 participants enrolled in Phase I, SSPG was assessed in a subset of 221 individuals (summary statistics for this subset are shown in [Table 1](#pone.0135681.t001){ref-type="table"}). When assessed at follow-up (i.e. PhaseTable](#pone.0135681.s003){ref-type="supplementary-material"}. The *p* values were not significant except for rs8191974 (which had an association *p* value of 0.032 for waist-hip ratio). However, three SNPs (rs8191973, rs8191974 and rs7323932) were associated with SSPG levels (*p* = 0.007, *p* = 0.03 and *p* = 0.011, respectively). A similar trend was seen when the Chinese Han population was analyzed separately (data not shown), however this association became non-significant for SNPs rs8191974 and rs7323932 when the analysis was performed conditional on rs8191973 (data not shown). The adjusted *p* values for multiple testing based on the Monte Carlo simulations are also shown in [Table 2](#pone.0135681.t002){ref-type="table"} for tests with *p* values \< 0.05. The adjusted *p* value was 0.05 for the smallest *p* value (0.007), which was still significant after stringent correction. However, no


other significant correlations were observed between *Gas6* polymorphisms and other indices of IR including HOMA-IR and FPI. For Model 2 that the three lifestyle factors were included as covariates, in general, the *p* values after adjusting for the lifestyle factors were similar to those without the adjustment in Model 1. The association of rs8191973 with SSPG remained significant (*p* = 0.007). [Table 3](#pone.0135681.t003){ref-type="table"} shows the interaction tests between the SNPs and the lifestyle factors. Interestingly, the SNP rs8191973 showed an interaction *p* value of 0.007 with physical activity, while the *p* value for the main effect of the SNP was 0.018 ([Table 3](#pone.0135681.t003){ref-type="table"}). However, the interaction *p* value was not significant after adjusting for multiple interaction tests for the four SNPs and three lifestyle factors for four traits.insulin, HOMA-IR: homeostasis model assessment of insulin resistance.

^1^ Model adjusted for age, gender, site, and ethnic population.

^2^ Model adjusted for age, gender, site, BMI, and ethnic population.

^3^ Analysis with log transformation

^4^ Model does not include lifestyle factors as covariates

^5^ Model includes lifestyle factors as covariates

^6^ Adjusted p-value for multiple testing

^7^ Adjusted means and 95% CI

^8^ Odds ratios and 95% CI

^9^ No data in the category

10.1371/journal.pone.0135681.t003

###### Interaction tests between SNPs and lifestyle factors.

![](pone.0135681.t003){#pone.0135681.t003g}

  SNP


Hospital stay and discharge outcomes after knee arthroplasty.
The impact of shorter hospital lengths of stay on patient outcomes at discharge from acute care after knee arthroplasty was investigated in a prospective observational outcome study at three Melbourne public hospitals during a 5-month period from October 1999 to March 2000. The participants were 105 consecutive patients (35 at each hospital), with a mean age of 71 years. Outcome measures were length of stay, destination (home or rehabilitation) and functional mobility at discharge from the acute care facility. During the study period mean hospital length of stay across the three hospitals was 6.5 days, more than 30% less than the Victorian average for the preceding year. This was associated with high rates of discharge to rehabilitation facilities (mean 64%), withbit funky, perfectly reflecting Bombet’s and Oh’s personalities. The only thing about this place that weirded me out was how the server cooked all the meat for us, which meant there was someone leaning over our table for the better part of our meal. Maybe Hanjip restaurant feels this is necessary for the guests who aren’t used to this kind of dining experience, or maybe this is meant to be part of the elevated offerings, but I could do with less of this babysitting. Let me at the meat!

06

12 2015

While foodies have been fawning over Terrine restaurant‘s Chef Kris Morningstar’s dining menu of French-meets-California cuisine (and with good reason), the Terrine cocktail menu is not to be overlooked.

Barman Ryan Wainwright, formerly of Tasting Kitchen, has an extraordinary talent


acquisition can seriously undermine the validity of the imaging results. Responsive agents can only provide information on the levels of endogenous species present if the concentration of the agent is known. ParaCEST agents are a new class of imaging agent that offer potential solutions to these problems. The contrast generated by paraCEST agents can be turned on or off by the operator. A low energy pre-saturation pulse is applied to turn on contrast;if the pulse is not applied then a 'without contrast'image is acquired. Thus, by using paraCEST agents the pre- and post- contrast images could be acquired simultaneously by interleaving the acquisitions. In this way motion artifacts could be reduced or even eliminated. Similarly, the use of responsive agents could be made more viable by introducing acase where it is set small. The maximum delay Dmax is lowered in the case where the cut-off frequency is set high compared with the case where it is set low.
Accordingly, when the delay circuit is realized with an APF in the case of CDs, the gain of a reproducing signal of a pit having the narrowest pit width 3T (where T is the clock period) and having a high frequency of occurrence, may be reduced in DVDs, or the delay may deviate from a constant range. As a result, it becomes difficult to accurately conduct tracking control or accurately provide the reproduced signals. Further, when a delay circuit having a time constant without deterioration of its frequency characteristic is to be manufactured, the circuit will become larger


= k**2 + 13*k + 6. Let l = -188 + 176. Determine u(l).
-6
Let v(q) = -q - 4. Suppose 4*c + 0 = o - 6, -2*c = -2*o + 12. Suppose j = -2*j - o. Give v(j).
-2
Let b = -15 + 13. Let v(j) be the first derivative of -2*j**3/3 - 5*j**2/2 + 9*j + 2. Let w(s) = -s**2 - 3*s + 4. Let c(t) = b*v(t) + 5*w(t). Calculate c(-4).
6
Let h(q) = q**3 + 7*q**2 + 3*q - 5. Let a(v) = -14*v + 8. Let x be a(1). Give h(x).
13
Let c(x) = -2*x**2 + 3*x - 2. Let k(z) = -z**2 + 5*z - 3. Let h be k(6). Let a(n) = -n**2 - 8*n + 11. Let v be a(h). What+ 5657. Suppose -1021 - g = -11*m. What are the prime factors of m?
2, 3, 11
Let a be 2247/107 + 5*1 + 0. List the prime factors of (3 - (-17*a - -5)) + -5.
3, 5, 29
What are the prime factors of (-85761)/5*((-98)/


Not only proportions need to be kept on thin lines, but also an individual face going wrong may disrupts entire portrait, not only that but group photos tends to be smaller and not close-up the way individual photographs might be, adding up complexity.

In past, I had tried only once about group sketches and not really great way, so I had to give it a try again. I been choosing the way to create and refine the outline first before proceeding with shadings and shadings too with one character at once. No fixed rules though.

After the last attempt, I thought to give it one more try and this time thought to make a video of entire sketching but sadly the camera positioning wasn’t proper and rather than the sketch,her artwork at the hospital, her work drew attention and gallery representation. After that time, she increasingly focused on her artwork until her death in 1994.

In addition to having eleven children, Harvey had twenty-eight grandchildren and three great-grandchildren.

Work
To support her 11 children, at night while everyone was asleep Harvey would make dolls. Harvey's sculptures were typically wood decorated with paint, beads, shells, cloth, and other found materials, combining "performance (on the order of a puppet show) sculpture, painting, and assemblage". Her work first gained attention when she entered a piece in the Blount Memorial Hospital's annual art show in 1974, where she was working as a housekeeper's aid. One of the staff doctors introduced her to the directors of the Cavin-Morris Gallery in New York City, which continued


Holidays to Gumbet

Gumbet is the nearest beach resort to Bodrum which is just two kilometre away or 10 minutes on a Dolmus (local bus service). Originally there was only a beach in Gumbet but today it has grown into a thriving holiday resort for singles, couples, friends and families in its own right.
Gumbet has a central main street which is full of colourful restaurants, bars and entertainment. The nightlife in both Gumbet and nearby Bodrum is considered to be among the best in Turkey with plenty of music and dancing available until the early hours of the morning.al. reported the ratio of malignant transformation from benign poroma to malignant one to be around 18%.[@bib0180] Our case presented with 10 year history of a mass in his postero-medial aspect of left forearm without significant symptoms apart from last 2 months which increased in size rapidly. Metastasis is reported to occur in 20% of patients while current review among 36 studies and 61 patients showed that metastasis occur in 26%. The most common affected organ to which EP metastise is lymph nodes (60%) followed by chest (13%), [Table 3](#tbl0015){ref-type="table"} shows the involved organs in literatures with their frequency of affection [@bib0005], [@bib0030], [@bib0050], [@bib0055], [@bib0070], [@bib0080], [@bib0110], [@bib0120], [@bib0125], [@bib0140], [@bib0155], [@bib0165], [@bib0170]. Our case showed metastasis to lung, cervical lymph nodes and brain. Mortality rate in case


             [@bib0025], [@bib0060], [@bib0065]
  31--40             0/0
  41--50             6/11                         [@bib0030], [@bib0070], [@bib0075], [@bib0080]
  51--60             9/16             field that was searching for more diversity in their candidates.

We now know that the second option is more probable after the prospective presidential candidate decided to make a huge deal out of taking a DNA test, that, in reality, only proves she is as white as I am. A ludicrously unskeptical Boston Globe story about Warren’s dramatic decision to take the test begins by contending that there’s “strong evidence’’ of Warren’s Native American’s ancestry dating back 6 to 10 generations—which creates the impression that she has Native American family littered over the past 100 years.

In truth, we learn, it’s possible that Warren’s great-great-great grandmother was partially Native American. This would make her around 1/32nd American Indian, a far cry from any reasonable threshold to embrace minority status for


a job. That’s exactly what she did starting in the 1990s, before walking back her claims when it became politically expedient.

Then again, being 1/32 (and really, the math says 1/64th) Native American is the high-end possibility. It is just as possible that Warren 1/1,024th Native American. (The story intially claimed it was 1/512th.) So maybe her great-great-great-great grandmother was part Cherokee.

Maybe.

Whatever the number is, there’s little genetic data available from Native Americans because of fears of exploitation (Warren’s case might be good example of why). There is no way to break down the DNA into region or tribe. The DNA tests merely rely on some guesswork by referencing the DNA to people from South America.

As The Federalist’s Sean Davis points out, according to The New York Times, thedevelopment of open-source hardware has the great potential to significantly reduce the cost of performing experimental science and make high-quality scientific tools available to everyone, from the most prestigious laboratories to the laboratories in the resource-poor developing world \[[@pone.0193744.ref006], [@pone.0193744.ref012]\].

According to the literature, there is a great number of various open-source "do- it- yourself" devices, such as: a potentiostat \[[@pone.0193744.ref013]--[@pone.0193744.ref015]\], syringe pump \[[@pone.0193744.ref016]\], a colorimeter \[[@pone.0193744.ref017]\], as well as additional laboratory equipment \[[@pone.0193744.ref004], [@pone.0193744.ref018], [@pone.0193744.ref019]\], which researchers can construct and adjust to their needs at a small fraction of the cost of available commercial offers. However, to our knowledge, the open-source pH device for maintaining pH values has been constructed in a considerably smaller scope \[[@pone.0193744.ref020]\].

Considering that the average cost of commercially available pH stat unit and software


for use in other mathematical and statistical software.

We used Debian \[[@pone.0193744.ref036]\] as the Operating System (OS) because it is a stable and well-supported GNU-Linux distribution, suitable for work on old computers. While working on "OpenPhControl", it was taken into consideration that only platform-independent frameworks and modules could be used, so the whole system will work on other OS which supports Java. It was successfully tested on Windows 7 and Windows 10.

pH measurement {#sec005}
--------------

The basic function of pH meter devices, i.e. the measurement of a pH value of solution, is typically achieved by using specialized electrodes in which the difference in electrical potential between a pH electrode and a reference electrode is transformed in a corresponding pH value. Regardless of the operation method, the one thing that all pHgetting images from build-in or USB-connected PC webcams, as well from IP/network cameras \[[@pone.0193744.ref038]\]. It is published under permissive free software license---the MIT License (MIT).

Overall image processing was obtained on the RGB video frames (640 x 480 pixels) directly from the memory.

### Digit recognition {#sec007}

The CANYON camera (CHR-WCAM43G, f4.8mm) was selected to display the pH meter, and measured pH value was recorded and processed with "OpenPhControl" software. For the basic image/video manipulation, pure Java cross-platform image processing framework that provides features for image and video frame processing, multi-threading image processing, GUI integration---Marvin \[[@pone.0193744.ref039]\], was used. Marvin is released under the GNU Lesser General Public License (LGPL).

The code for Optical Character Recognition (OCR) that recognizes digits on a 7 segment display was developed. The used pH meter has a


basic design to the online project repositories as appropriate. For this, please contact the authors directly.

Conclusion {#sec022}
==========

Reliable and inexpensive open-source pH stat, designed from readily available laboratory devices (a pH meter, a computer, a webcam), open-source "OpenPhControl" software, inexpensive hardware (a peristaltic pump, Arduino, a step motor...) and some 3D printed parts were constructed and evaluated.

The open-source software "OpenPhControl", controlled by Arduino microcontrollers with a USB connection, was designed to use pump modules. Two pump modules were designed (a low cost peristaltic pump and an upgraded open-source syringe pump) by defining their hardware and specialized firmware, which enabled them to be used. Considerations were made for ease of assembly and reduced costs without compromising performance.

In addition to the basic functions of pH stat, i.e. the pH value measurementQ:

Pass Object reference within Intent without implementing Serializable or Parcelable

I know similar questions have been asked multiple times. I think i read most of it. But none answer is applicable.
I need to pass complex Objects via Intents (Activity calls/Broadcasts). Everything is done within my process. That's why I see no reason to write my objects into Streams just to reassemble them a few milliseconds after. I want to pass my object reference through my application. Is there any way to do this.
Since my application will broadcast the same Event multiple times in a row I can't rely on static members. I need to get exacly the same object for what I broadcasted.
That's why I was thinking about a static "Referenceholder" that will accept an Object and return an


integer that identifies this object in it's internal list so I can pass this integer via .putExtras. But as far as I know Java I could not clean up this Object from this list after it has been added because multiple Listeners could be interessted in the very same object and I would have to keep it in my Referenceholder for ever (assuming that a thread may be resumed at any time - even 2 minutes later).
Any ideas? Am I doing something wrong? Or any ideas of how I can clean up my referneces (probably after some seconds? this may lead to a crash but it seems to be more applicable than writing code that assembles and reassembles my objects for no reason)

A:

Your options are pretty clear: Well, it’s about time they came forward and explained themselves! Courtesy of Funny or Die and a delightful group of actors (Nick Offerman, Tim Meadows, Judd Nelson, Kurtwood Smith, Ray Wise, Corey Stoll, and Brian Flaherty) those poor, misrepresented men finally get the opportunity to explain exactly why they are better at talking about women’s health issues than women are. Full disclosure, I could only watch about 28 seconds because I started to have my period. I always have that!

(via Pajiba)

Previously in Women’s Health

Have a tip we should know? tips@themarysue.com


Investigation on the surface hydrophobicity and aggregation kinetics of human calprotectin in the presence of calcium.
Calcium and zinc binding protein, calprotectin is a multifunctional protein with broad spectrum antimicrobial and antitumoural activity. It was purified from human neutrophil, using a two-step ion exchange chromatography. Since surface hydrophobicity of calprotectin may be important in membrane anchoring, membrane penetration, subunits oligomerization and some biological roles of protein, in this study attempted to explore the effect of calcium in physiological range on the calprotectin lipophilicity. Incubation of human calprotectin (50 microg/ml) with different calcium concentrations showed that 1-anilino-8-naphthalene sulfonic acid (ANS) fluorescence intensity of the protein significantly elevates with calcium in a dose dependent manner, suggesting an increase in calprotectin surface hydrophobicity upon calcium binding. Our study also indicates that calcium. [the] District['s] Reply" she sought to disavow that concession ("Officer Flynn was not on an emergency call at the time," J.A. 7), her reasoning appeared to substitute an objective test ("this was not an emergency situation" because Flynn did not "follow departmental procedure," J.A. 7) for the simpler inquiry mandated by the statute of whether Flynn believed"genuine[ly]"that he should proceed expeditiously on a mission. Duggan v. District of Columbia, 884 A.2d 661, 663 (D.C.2005) (en banc).[2] Hence, the trial judge can scarcely be faulted for concluding that appellant had pointed to "no evidence and no reason to question Officer Flynn's belief" in this regard and that, indeed, she "concedes that the gross negligence standard properly applies" (J.A. 2). See, e.g., Vessels v. District of Columbia, 531 A.2d


   try
    {
      mpAppContext->setup();
    }
    catch(const std::exception& e)
    {
      mScreen.showWarning(e.what());
      mScreen.registerWifiCallback();
      return;
    }
    if (!mpAppContext->getModel().hasWifiCredentials())
    {
      mScreen.showWarning("AP: HomePoint-Config, IP: 192.168.99.1");
      return;
    }
    mScreen.showWarning("Loading Screen");
    mScreen.setupData();
  }

  void runLoop(void *pvParameters)
  {
    for(;;)
    {
        if (loopTaskWDTEnabled)
        {
        with bikes that deliver power only when pedaled.

IMBA has supported Class 1 e-bikes on trails, as long as local land managers and mountain bikers are involved in the process of reviewing and approving that access, said IMBA’s executive director and legendary mountain biker David Wiens.

But most important, Wiens said, “is we don’t want to see access threatened by the introduction of Class 1 bikes on trails. As soon as access becomes an issue, we are no longer supportive.”

IMBA, while supporting a public process for allowing pedal-assisted e-bikes on trails, thinks they should be officially designated differently than mountain bikes. So those signs with the icons for bikes, hikers, horses, motorbikes and Jeeps should include an e-bike icon.

“We don’t want to see traditional nonmotorized mountain bikes and Class 1


{
      f_forl = makeasmfunc(lj_bc_ofs[BC_FORL]);
      f_iterl = makeasmfunc(lj_bc_ofs[BC_ITERL]);
      f_loop = makeasmfunc(lj_bc_ofs[BC_LOOP]);
      f_funcf = makeasmfunc(lj_bc_ofs[BC_FUNCF]);
      f_funcv = makeasmfunc(lj_bc_ofs[BC_FUNCV]);
    } else {  /* Otherwise use the non-hotcounting instructions. */
      f_forl = disp[GG_LEN_DDISP+BC_IFORL];
      f_iterl = disp[GG_LEN_DDISP+BC_IITERL];
      f_loop = disp[GG_LEN_DDISP+BC_ILOOP];
      f_funcf = makeasmfunc(lj_bc_ofs[BC_IFUNCF]);
      f_funcv = makeasmfunc(lj_bc_ofs[BC_IFUNCV]);
    }
    /* Init static counting instruction dispatch first (may be copied below). */
    disp[GG_LEN_DDISP+BC_FORL] = f_forl;
    disp[GG_LEN_DDISP+BC_ITERL] = f_iterl;
  */
  }
  return 1;  /* OK. */
}

/* Enforce (dynamic) linker error for version mismatches. See luajit.c. */
LUA_API void LUAJIT_VERSION_SYM(void)
{
}

/* -- Hooks --------------------------------------------------------------- */

/* This function can be called asynchronously (e.g. during a signal). */
LUA_API int lua_sethook(lua_State *L, lua_Hook func, int mask, int count)
{
  global_State *g = G(L);
  mask &= HOOK_EVENTMASK;
  if (func == NULL || mask == 0) { mask = 0; func = NULL; }  /* Consistency. */
  g->hookf = func;
  g->hookcount = g->hookcstart = (int32_t)count;
  g->hookmask = (uint8_t)((g->hookmask & ~HOOK_EVENTMASK) | mask);
  lj_trace_abort(g);  /* Abort recording on any hook change. */
  lj_dispatch_update(g);
  return 1;
}

LUA_API lua_Hook lua_gethook(lua_State *L)
{
  return G(L)->hookf;
}

LUA_API int lua_gethookmask(lua_State *L)
{
  return G(L)->hookmask & HOOK_EVENTMASK;
}

LUA_API int lua_gethookcount(lua_State *L)
{


an extra-dimensional entity whose existence is predicted by Stephen Hawking’s black hole information paradox; others suggest Neville is just a high-flying wrestler whom commentators are describing in hyperbolic terms.

While gathered at CERN, the physicists will also debate the possibility of finding intelligent life in the WWE Universe.for the first time.”

But where – in this day and age – can you find a person who didn’t grow up with Mickey Mouse or Bugs Bunny?

An image of the deepest, darkest rainforest springs to mind, a monk perched on a rock in the mountains of the Himalayas, a rice farmer in the farthest provinces of China. Surely there was someone out there who had never been exposed to cartoons.

What we didn’t know was that we were about to embark on a journey that would bring us face-to-face with fascinating people – people who would have a truly significant impact on our lives.

As I write this post, I wear a bracelet that serves to remind me about the importance of gratitude — a lesson that I learned on


visiting them. Now we had the motivation to do so.

The Hadzabe are a nomadic people. They are one of the last hunter-gatherer tribes in the world. You may have heard about them because they have a distinctive language that uses these unusual clicking sounds. They live completely separate from society and technology, with no electricity or running water. They live only from the land and from barter with other tribes.

The Hadzabe’s staple foods are berries, Baobab fruit, corn and animals hunted with spears and a bow and arrow. They move from place to place, only staying in a location while they are able to collect fruit and hunt for animals in the area. They have almost no interaction with the modern world, and are reluctant to let outsidersand stand up comedian!!!

I made a Powtoon about a Hadza man making fire in the middle of the screen. HanXa pointed out that the fire was burning the man’s legs. In response, I made the fire huge! This was met with raucous laughter from everyone.

We were LITERALLY rolling on the floor laughing. The guys were cracking up, and the children wanted to know how they could get inside the screen.

The connection was instantaneous. The laughter, totally infectious. Even though these Hadza did not grow up with Saturday morning cartoons — they immediately connected to this form of art.

After making another Powtoon about the Hadza “coming of age ritual,” Akko, one of the younger members of the tribe, wanted to try it out for himself.

He had seen me use


children after a departed soul within three months of his life.

You see, as idyllic as the Hadza existence may appear to an outsider, there are significant challenges.

In the last ten years, the Hadzabe population has declined from 8,000 to less than 700.

The difficulty doctors have reaching the Hadza contributes to this decline. Infant mortality is high, and what might be a small problem can quickly become life threatening.

Of course, the Hadzabe (and many other indigenous peoples) need to be assisted in the way that works best for them. Heavy-handed moves in the past to force a settled lifestyle, or to provide state assistance have often done far more harm than good.

We have suggested our help, and are in close contact with Mustafa to provide any care they needsure, those who bet against Tesla at the start of 2019 are still in the black to date with the equity down more than 11% this year after Thursday's price moves. Tesla stock closed at $254.68 on Wednesday, which at the time represented a 23.4% slide for 2019.


image of the hospital in the professional community and to the general public.

Skills and Basic Qualifications

A Doctor of Veterinary Medicine (DVM) or related degree from an accredited university.

New graduates encouraged to apply!

Licensure in good standing to practice in AR.

Commitment to practicing the highest standard of medicine and upholding veterinary code of ethics.

Demonstrates excellent verbal and written communication skills.

Works collaboratively with hospital team members.

Makes decisions confidently and effectively.

Manages time and tasks appropriately.

Models a professional and courteous manner with staff and clients.

Commitment to ongoing educational development and growth.

If you are looking for an excellent practice, with unmatched growth potential, we want to hear from you! Please apply today!

Equal Employment Opportunity

It is the policy of the company to afford equal opportunities to all applicants and employees regardless of race, color, religion,Oprah Winfrey waded deeper into political waters this summer by promoting the “Shout Your Abortion” movement and its attempts to normalize the killing of unborn babies.

The July issue of her “O” magazine featured “Shout Your Abortion” founder Amelia Bonow in its “Inspiration” section, CNS News reports.

Bonow, who began the campaign to urge women to brag about aborting their unborn babies, soon will be coming out with a new book by the same title, according to the report.

She told the magazine how it all began in 2015: “[W]hen I found out that the House of Representatives had voted to defund Planned Parenthood. I kind of unraveled.

“I opened Facebook and, without thinking, wrote, ‘Like a year ago, I had an abortion at Planned Parenthood…and I remember this experience with a


of us who speak out, the clearer it becomes that all sorts of people have abortions, including people you love.”

But it really is her own movement, the pro-abortion movement, that silences women whose abortion stories do not fit their narrative. Bonow’s pro-abortion campaign is not the first abortion story-telling movement either.

Long ago, pro-life advocates recognized the power of individual people and their stories in the abortion debate. The Silent No More Awareness campaign is just one example of the many pro-life storytelling outreaches. It encourages people who experienced pain and regret after their abortions to share their stories publicly, and its website documents thousands of stories of mothers, fathers, grandparents and others who experienced deep pain and remorse because of unborn babies’ abortion deaths.

“O” magazine is doing athe previous class="error". I allready tryied to access to that object with :
$('#reponse137-3').prev(".error")

but it doesn't work. I think because it hasn't the same parent, so I tryied :
$('#reponse137-3').prev("tr").next(".error")

How can I do ?

A:

Assuming your .error div is always in the same table row:
$('#reponse137-3').closest('tr').find('.error:first');

http://jsfiddle.net/vkfF8/


(all versions), GuardLogix 5560 controllers (all versions), 1769 CompactLogix L23x controllers (all versions), 1769 CompactLogix L3x controllers (all versions), 1768 CompactLogix L4x controllers (all versions) , and 1768 Compact GuardLogix L4xS (all versions).

FRN 19.00 SoftLogix 5800 controllers (all versions), RSLogix Emulate 5000 (all versions), ControlLogix 5560 controllers (all versions), ControlLogix 5570 controllers (all versions), ControlLogix 5560 Redundant controllers (all versions), GuardLogix 5560 controllers (all versions), 1769 CompactLogix L23x controllers (all versions), 1769 CompactLogix L3x controllers (all versions), 1768 CompactLogix L4x controllers (all versions), and 1768 Compact GuardLogix L4xS controllers (all versions).

FRN 20.00 SoftLogix 5800 controllers (all versions), RSLogix Emulate 5000 (all versions), ControlLogix 5560 controllers (v20.010 through v20.013), ControlLogix 5570 controllers (v20.010 through v20.013), ControlLogix 5560 Redundant controllers (v20.050 through v20.055), ControlLogix 5570 Redundant controllers (v20.050 through v20.055),in the case where a white park lamp and an amber front turn lamp is optically combined, when the front turn lamp turns on, the amber color is diminished due to the white park lamp. This results in a configuration in which the perception is that the park lamp remains on throughout the activation of the front turn, but the turn lamp amber color may not appear as purely amber.
One solution to this problem was that the park lamp was converted to an amber park lamp or the white park lamp was separated from the front turn lamp for the North American market.
FIG. 1 is a front view of a generic vehicle 3. The vehicle 3 is equipped with parking lights 4, which are also used as daytime


Dynamics of Glucose Metabolism After Kidney Transplantation.
Posttransplantation diabetes mellitus (PTDM) impacts patient and allograft survival after kidney transplantation. Prediabetes, which is an independent risk factor for PTDM, is modifiable also in a post-transplant setting. Understanding the risks and dynamics of impaired glucose metabolism after transplantation is a key component for targeted intervention. A retrospective chart analysis of all adult non-diabetic renal allograft recipients (n=251, 2007-2014) was performed. Longitudinal follow-up included fasting plasma glucose and HbA1c, as well as data on allograft function and immunosuppression at consecutive time points (months 3-6 to >5 years post transplantation). Throughout follow-up, median prevalence of prediabetes and PTDM was 53.3 [52.4-55.7]% and 15.4 [15.0-16.5]%, respectively. Continuously high fluxes between states of glucose metabolism, with individual patients' state deteriorating or improving over time, resulted449
List the prime factors of 10407.
3, 3469
List the prime factors of 16651.
16651
What are the prime factors of 10154?
2, 5077
List the prime factors of 4038.
2, 3, 673
What are the prime factors of 6429?
3, 2143
List the prime factors of 67901.
67901
List the prime factors of 904.
2, 113
List the prime factors of 1616.
2, 101
What are the prime factors of 652?
2, 163
What are the prime factors of 774?
2, 3, 43
List the prime factors of 6779.
6779
What are the prime factors of 49031?
49031
What are the prime factors of 27777?
3, 47, 197
List the prime factors of 102.
2, 3, 17
List the prime factors of 32970.
2, 3, 5, 7, 157
List the prime factors of 45322.
2, 17, 31, 43
List the prime factors of 8209.
8209
List the prime factors of 56549.
193, 293
What are the prime factors of 1335?
3, 5, 89
List the


\\
 & = & \frac{i}{N}\mathbf{q}_{e}\cdot\mathbf{J}_{1\left(i'\mathbf{k}';i\mathbf{k}\right)},\label{eq:r_matrix}\end{aligned}$$ where the origin of coordinate operator $\hat{\mathbf{r}}$ is placed at the atom 1 in the PUC, and correspondingly the partial summation is only over the WFs centered at atom 1. We use $\mathbf{J}_{1\left(i'\mathbf{k}';i\mathbf{k}\right)}$ to denote the summation in parenthesis in the second line. Since momentum transfer $\mathbf{q}$ is highly suppressed by $m_{e}/m_{N}$, in derivation we assume $\left|\mathbf{q}_{e}\right|\cdot\left|\mathbf{r}\right|\ll1$, which is a good approximation for a sub-GeV DM. Similar discussion can be easily applied to the second atom located at $\boldsymbol{\tau}_{2}=\left(1/4,\,1/4,\,1/4\right)$, only keep in mind that the origin of operator $\hat{\mathbf{r}}$ is also placed at atom 1 in practical use of $\mathtt{Wannier\,90}$. After a translation, the corresponding transition amplitude for the atom 2 at the site $\mathbf{R}=\mathbf{0}$ is modified as $$\begin{aligned}
\left\langle i'\,\mathbf{k}'\right|\hat{G}_{\mathbf{0}2}\left(\mathbf{q}_{e}\right)\left|i\,\mathbf{k}\right\rangle  & \simeqband structures in a specific energy range, Bloch states spanning relevant range are faithfully retained in the subspace selection procedure, and such energy range is referred to as “frozen energy window”, or “inner window”. In this work, we choose a frozen energy window ranging from the bottom of the valence band to 40 eV above the valence band maximums (VBM), which is also reflected in Fig. \[fig:Band\].

In practical computation of the form factor Eq. (\[eq:crystal Form Factor\]) we use an bin width $\Delta E=0.059\,\mathrm{eV}$ to smear the delta function, and the integrand is evaluated at the central value in each energy bin. Besides, the integrals of the continuous $k$-points in the 1BZ are replaced by corresponding summations over the uniform 16$\times$16$\times$16 $k$-points. In the right panel of Fig. \[fig:Band\] shown is


assumed.

\[sec:Conclusions\]Summary and prospects
========================================

In this paper we presented a tight-binding approach to describe the Migdal effect in the diamond crystal. This localized description is a natural choice to generalize the well established treatment for isolated atoms to the case in crystalline solids. To achieve such TB description we generate a set of atom-centered WFs by use of software packages $\mathtt{Quantum\,Espresso}$ and $\mathtt{Wannier\,90}$. While the localization effect of the recoiled atom is preserved in forms of WFs, the delocalized nature of the Bloch states in solids is encoded in the hopping terms at the same time. Based on these hopping integrals, the electronic excitation rates induced by the recoiled ion were computed straightforwardly.

Here we make some comments on our methodology. As has been noted in previous section, our method deviatesused $s$, $p$ atomic orbitals and $sp^{3}$ hybrids as trial orbitals $\left\{ g_{n}\left(\mathbf{r}\right)\right\} $ to wannierize and calculate the transition event rate respectively, and the difference between the two results turns out to be well within a few percent, underlining a good agreement. Thus our approach has proved both effective and self-consistent.

As a last remark, we note that our method in dealing with the Migdal effect in semiconductor is rather *ad hoc* and preliminary, mainly due to the limitation that the WFs should be atom-centered, which prevents further minimizing the spreads of the WFs in implementation of established codes such as $\mathtt{Wannier\,90}$. Nevertheless, from above discussions, this hurdle can be circumvented if one wannierizes the initial valence states and the final conduction states in separate steps and in


complementary energy windows. This brings two benefits: (1) the initial valence states alone can be readily wannierized as atom-centered WFs, *e.g.*, either in the forms of $sp^{3}$ hybrids or $s$, $p$ atomic orbitals; (2) the final conduction states alone can be optimally wannierized without the need to to atom-centered. Moreover, since the valence and conduction states are orthogonal, the corresponding sets of WFs are automatically orthogonal to each other, at least in theory. Of course, some modifications need to be made in underlying codes. We hope that our work will stimulate further optimization on these problems from a wider community.

\[sec:Appendixa\]Maximally localized Wannier functions
======================================================

Since our practical realization of the atom-centered WFs are closely related to the generation of the maximally localized Wannier functions via implementing software $\mathtt{Wannier\,90}$ [@MOSTOFI20142309], here wegauge $\mathbf{U}^{\left(\mathbf{k}\right)}$ on the term $\tilde{\varOmega}$. Since the matrix $U_{\mathbf{k}}$ in Eq. (\[eq:Bloch-like orbital\]) has already provided $J$ sufficiently localized WFs, we use them as the starting point for the iterative steepest-descent method to reach the optimal unitary transformation $\mathbf{U}^{\left(\mathbf{k}\right)}$ that minimizes $\tilde{\varOmega}$. This procedure is called gauge selection.

In more general cases, additional modifications are required to pick the Bloch orbitals of interest from those unwanted ones when the bands are crossing with each other. The Souza-Marzari-Vanderbilt method proposed in Ref. [@PhysRevB.65.035109] successfully realized such disentanglement. In this approach, one first identifies a set of $\mathcal{J}_{\mathbf{k}}\geq J$ Bloch orbitals that form a $\mathcal{J}_{\mathbf{k}}$-dimensional Hilbert space at each point $\mathbf{k}$ in the 1BZ in a sufficiently large energy range, which is dubbed as “disentanglement window”, or “outer window”, and then chooses


a $J$-dimensional subspace that gives the smallest possible value of $\varOmega_{\mathrm{I}}$ via iterative procedures. Similarly to above discussion, the minimization of $\varOmega_{\mathrm{I}}$ also begins with a rough initial guess that are usually obtained by first projecting $J$ localized trial orbitals $\left\{ g_{n}\left(\mathbf{r}\right)\right\} $ onto $\mathcal{J}_{\mathbf{k}}$ Bloch states such that $$\begin{aligned}
\left|\phi_{n\mathbf{k}}\right\rangle  & = & \sum_{j=1}^{\mathcal{J}_{\mathbf{k}}}\left|j\,\mathbf{k}\right\rangle \braket{j\,\mathbf{k}|g_{n}},\label{eq:projection}\end{aligned}$$ and then constructing the following $J$ orthonormalized Bloch-like states $\widetilde{\left|i\,\mathbf{k}\right\rangle }$ that are related to the original $\left|i\,\mathbf{k}\right\rangle $ via a $\mathcal{J}_{\mathbf{k}}\times J$ matrix $V_{\mathbf{k}}$ such as $$\begin{aligned}
\widetilde{\left|i\,\mathbf{k}\right\rangle } & = & \sum_{j=1}^{\mathcal{J}_{\mathbf{k}}}\left|j\,\mathbf{k}\right\rangle V_{\mathbf{k},ij}.\end{aligned}$$ An algebraic algorithm that updates the minimization iteratively is then used to obtained $J$-dimensional optimal subspace in a self-consistent manner. This process is called subspace selection. Once the optimal subspace is determined, *i.e.*, the minimization of $\varOmega_{\mathrm{I}}$ isair rifle inside a Walmart in Ohio, according to WLWT TV.

Lynch, who was confirmed as the U.S. Attorney earlier this month, met with Crawford’s family Tuesday during a visit to Cincinnati to discuss police reform, reports the television news station.

Crawford’s parents tell the station that Lynch met with them for about 15 minutes, and pledged to investigate the shooting, which drew protests over the killing of young Black men by police around the country.

The family has filed a suit against the city of Beavercreek, the two Beavercreek officers involved, the police chief, and Walmart Stores Inc., charging negligence and violation of Crawford’s civil rights.

The Department of Justice conducted an investigation and found that the Miami Police Dept. (MPD) engages in a pattern or practice of excessive force with


-i(o) - 4*s(o).
35*o - 5
Let n(p) = p**3 - 1. Let s(t) = -5*t**3 + 2. Let g = -12 - -55. Let f(q) = q**2 + 7*q - 16. Let m be f(-12). Let d = g - m. Determine d*s(j) - 2*n(j).
3*j**3
Let f(q) = -66*q - 64. Let r(k) = -332*k - 326. Determine -16*f(d) + 3*r(d).
60*d + 46
Let o(p) = 216 - 8*p**2 + p**2 + 6*p**2 - 217 + p. Let h(j) = 10*j - 10. Calculate h(x) - 10*o(x).
10*x**2
Let u(m) = -12*m**2 - 10*m - 5103. Let q(i) = -5*i**2 - 4*i - 2552. Give 5*q(f) - 2*u(f).
-f**2 - 2554
Let q(w) = w - 1. Suppose -2*g + 64 = -2*s, -g = 20*s - 18*s + 76. Let m(c) = -48*c +not rotate!
<video></video>

Tested on IOS 5.1 Iphone 4.
(I hope no one will file this as a bug! ;) ).

A:

Using jQuery, it's alot shorter, HTML structure:

Javascript:
setTimeout($.proxy(function(){
   this.css("position", "");
}, $('<video style="visibility:hidden; position:absolute; width:1px; height:1px">').before("img")), 0);

Note: The timeout prevents display errors where positions are incorrect sometimes.
Works like a charm on iOS 7.1, 7.0 and 6.1!


come. If you can't do it as well as you want for now, give it a little bit of a break and come back to it. Long concentration and tiredness will all make learning difficulter.

Our next two workshops are full so we're looking a February now for classes which is just fantastic - more people wanting to learn is a great thing and helps keep the craft alive!

Just a note on Diane's wheel which was really the prettiest wheel I've ever seen, the photo doesn't do it justice, but (and I'm sure she wouldn't mind me saying) it was second hand. It just shows you that if you shop around you can find a wonderful second hand wheel without breaking the bank. Before you part with your wellhad to spend each day of this week at the hospital which has been really frustrating!

Still! We had a good laugh on Saturday at the workshop at Knit-Wise with Mark, Heather and Alison who all spun valiantly all day through wind rain and cold. We were inside drinking tea and coffee like there was no tomorrow but some poor bride braved the elements to get married so we didn't feel too badly done by.

Here are the finished skeins by the rightly proud spinners, it's always great to meet people with the same passion as yours, but also new friends from Ravelry and Etsy. Alison came all the way down from Blackpool - thats dedication and Heather came from locally but is off to London so it was nice


and others. In the second conversation, Erwin indicated he wanted Fischer back at the company, but only if Fischer rejoined the church.

II. Discussion
Fischer sued Forestwood under Title VII for unlawful discharge, retaliation, and failure to hire.[1] The district court granted *978 Forestwood summary judgment on all three claims. In reaching this decision, the court also decided the two recorded conversations between Fischer and Erwin were inadmissible hearsay.

A. Standard of Review
We review a grant of summary judgment de novo. Piercy v. Maketa, 480 F.3d 1192, 1197 (10th Cir.2007). Summary judgment is warranted only "if the pleadings, depositions, answers to interrogatories, and admissions on file, together with the affidavits, if any, show that there is no genuine issue as to any material fact and that the moving party is entitledqualified for a job for which the employer was seeking applicants; (2) despite being qualified, the plaintiff was rejected; and (3) some additional evidence to support the inference that the plaintiff was not hired because of a discriminatory motive based upon the employee's failure to hold or follow his or her employer's religious beliefs. Upon such a showing, the plaintiff is entitled to the benefit of the McDonnell Douglas burden-shifting scheme and its presumptions. Exum, 389 F.3d at 1134-35.
Alternatively, a plaintiff alleging a failure-to-hire claim may survive summary judgment if he produces sufficient direct evidence of discrimination. Direct evidence would support an inference that religious discrimination played a motivating factor in an employer's decision not to hire the applicant. Cf. Fye v. Oklahoma Corp. Comm'n, 516 F.3d 1217,


recordings on summary judgment, concluding that the conversations were impermissible hearsay. The district court furthermore concluded that even if the conversations were admissible, they were *984 insufficient to establish a prima facie case. We disagree with both conclusions.

1. Admissibility of telephone conversations
"[W]e review a district court's evidentiary decisions for abuse of discretion." Champagne Metals v. Ken-Mac Metals, Inc., 458 F.3d 1073, 1081 (10th Cir.2006). "In reviewing [such a decision], we will not disturb the determination absent a distinct showing it was based on a clearly erroneous finding of fact or an erroneous conclusion of law or manifests a clear error of judgment." Harsco Corp. v. Renner, 475 F.3d 1179, 1190 (10th Cir. 2007).
Hearsay evidence is generally inadmissible. Fed.R.Evid. 802. Such evidence "is a statement, other than one madethe recorded tapes were admitted into evidence, Fischer presented insufficient evidence to survive summary judgment. Again, we disagree.
As an initial manner, the district court erred in concluding that Fischer failed to establish a prima facie failure-to-hire case. As explained above, to establish a prima facie case, Fischer must provide sufficient evidence establishing that (1) he applied and was qualified for a job for which Forestwood was seeking applicants; (2) despite being qualified, Forestwood rejected him; and (3) some additional evidence to support the inference that Fischer was not hired because of a discriminatory motive based upon Fischer's failure to follow the religious beliefs of Forestwood's management.
Fischer satisfied the first element because he sought reinstatement directly from Erwin, the president of the company. Fischer is not barred from pursuing


his claim merely because he did not submit a formal application. See Int'l Bhd. of Teamsters v. United States, 431 U.S. 324, 365-66, 97 S.Ct. 1843, 52 L.Ed.2d 396 (1977) ("When a person's desire for a job is not translated into a formal application solely because of his unwillingness to engage in a futile gesture he is as much a victim of discrimination as is he who goes through the motions of submitting an application."). In fact, it is unclear from the record whether Forestwood even accepts formal job applications from non-FLDS members. Fischer also produced sufficient evidence demonstrating he was qualified for a position, based on his prior successful performance with the company. Finally, Fischer demonstrated that a position was available at the company, based on Erwin'sIn the phone conversation, when Fischer asked Erwin whether he had a chance to check with other board members about Fischer returning to the company, Erwin said,
[Erwin]: Yeah, I've had a chance to talk it around a little bit, see what's going  One of the first questions I had was it just for a job or would you like to come back and be part of the people in the group, trying to kind of get back in where we were before or just what is your standing on it, or what's your thinking on it?....
[Erwin]: Drop this suit and let us get back on base and we could go forward again.
Mr. Fischer: Uh-huh.
[Erwin]: We would just be (inaudible) happy to have you here back with us


      [puppetlabs.services.ca.ca-testutils :as testutils]
            [puppetlabs.services.jruby.jruby-puppet-testutils :as jruby-testutils]
            [puppetlabs.kitchensink.core :as ks]
            [slingshot.test :refer :all]
            [schema.test :as schema-test]
            [clojure.test :refer :all]
            [clojure.java.io :as io]
            [clojure.string :as string]
            [clj-time.core :as time]
             csr-fn #(csr-stream "test-agent")
        ruby-load-path jruby-testutils/ruby-load-path
        ruby-gem-path jruby-testutils/gem-path]

    (testing "stdout is added to master's log at debug level"
      (logutils/with-test-logging
        (autosign-csr? executable "test-agent" (csr-fn) ruby-load-path ruby-gem-path)
        (is (logged? #"print to stdout" :debug))))

    (testing "stderr is added to master's log at warn level"
      (logutils/with-test-logging
       (autosign-csr? executable "test-agent" (csr-fn) ruby-load-path ruby-gem-path)
       (is (logged? #"generated output to stderr: print to stderr" :warn))))

    (testing "non-zero exit-code generates a log


(is (= (get-certificate-request csrdir "foo")
             (get-certificate-request csrdir "test-agent"))))))

(deftest autosign-certificate-request!-test
  (let [now                (time/epoch)
        two-years          (* 60 60 24 365 2)
        settings           (-> (testutils/ca-sandbox! cadir)
                               (assoc :ca-ttl two-years))
        csr       (is (true? (revoked? cert))))))

(deftest revoke-multiple-certs
  (testing "The revocation function can accept a list of certs to revoke"
    (let [settings (testutils/ca-sandbox! cadir)
          cert1 (-> (:signeddir settings)
                    (path-to-cert "localhost")
                    (utils/pem->cert))
          cert2 (-> (:signeddir settings)
                    (path-to-cert "test_cert")


 (let [key (-> settings :cakey utils/pem->private-key)]
        (is (utils/private-key? key))
        (is (= 512 (utils/keylength key)))))

    (testing "capub"
      (let [key (-> settings :capub utils/pem->public-key)]
        (is (utils/public-key? key))
        (is (= 512 (utils/keylength key)))))

    (testing "cert-inventory"
      (is (fs/exists? (:cert-inventory settings))))

    (testing "serial"
      (is (fs/exists? (:serial settings))))

    (testing "Does not replace files if they all exist"
      (let [files (-> (settings->cadir-paths (assoc settings :enable-infra-crl false))
        (testutils/master-settings tmp-confdir)
          ca-settings (testutils/ca-settings (str tmp-confdir "/ssl/ca"))
          cacrl       (:cacrl ca-settings)
          hostcrl     (:hostcrl settings)
          cacrl-text (slurp cacrl)]

      (testing "Copied cacrl to hostcrl when hostcrl not present"
        (retrieve-ca-crl! cacrl hostcrl)
        (is (= (slurp hostcrl) cacrl-text)
            (str "Unexpected content for hostcrl: " hostcrl)))

      (testing "Copied cacrl to hostcrl when different


"master" ca-settings)

    (testing "Generated SSL file"
      (doseq [file (vals (settings->ssldir-paths settings))]
        (testing file
          (is (fs/exists? file)))))

    (testing "hostcert"
      (let [hostcert (-> settings :hostcert utils/pem->cert)]
        (is (utils/certificate? hostcert))
        (testutils/assert-subject hostcert "CN=master")
        (testutils/assert-issuer hostcert "CN=Puppet CA: localhost")

        (testing "has alt names extension"
          (let [dns-alt-names (utils/get-subject-dns-alt-names hostcert)]
            (is (= #{"master" "onefish"key '" (:hostprivkey settings)
                   "' is missing"))
             (initialize-master-ssl! settings "master" ca-settings)))
        (fs/copy private-key-backup private-key-path)
        (fs/copy cert-backup cert-path)))

    (testing "hostcert regenerated if keys already present at initialization time"
      (let [hostcert-path (:hostcert settings)
            hostcert-backup (fs/copy hostcert-path (ks/temp-file))
            public-key-before-init (slurp (:hostpubkey settings))
            _ (fs/delete hostcert-path)


                    (select-keys % [:kind :msg]))]
                     ["subject contains wildcard character" "foo*bar" "bad-subject-name-wildcard.pem"
                      #(=  {:kind :invalid-subject-name
                            :msg "Subject contains a wildcard, which is not allowed: foo*bar"}
                  :msg "CSR contains a public key that does not correspond to the signing key"}
                          (select-keys % [:kind :msg]))]]]
              (testing policy
                (let [path (path-to-cert-request (:csrdir settings) subject)
                      csr  (io/input-stream (test-pem-file csr-file))]
                  (is (false? (fs/exists? path)))


[u all-perms
            g all-perms
            o all-perms]
      (let [tmp-file (fs/temp-name "ca-file-perms-test")
            perms (str u g o)]
        (create-file-with-perms tmp-file perms)
        (is (= perms (get-file-perms tmp-file)))
        (fs/delete tmp-file))))

  (testing "Changing the perms of an already created file"
    (let [perms-list (for [u all-perms
                          more about that study during
the Self-Regulation panel this afternoon,
but I wanted to make special note of it, as
this topic is one in which I have taken a
personal interest. I am delighted that the
MSRB has decided to review these important
issues as it seeks opportunities to improve
the quality of the municipal securities market
for the benefit of investors.
At the conclusion of all of the hearings,
the Commission staff will prepare a report
concerning what we have learned, including
their recommendations for further action that
we should pursue. These may include recommendations
for changes in legislation, regulations, and
industry practice. These hearings will be
instrumental in informing those recommendations.
I was very pleased that our Chairman Mary
Schapiro asked me to lead this series of field
hearings, as I have long had an interest in
strengthening investor protection mechanisms
applicable in this important market.


The Kontinental Hockey League (KHL), for economic reasons, have decided not to host Hope cup (also known as Nadezhda Cup) for teams that haven’t qualified for the Gagarin Cup playoffs.

The Management Board, after taking recommendations of the Board of Directors decided that in these economic circumstances it is not productive to host the Hope Cup. In order to motivate Hope Cup teams, a prize fund was also created which consisted of of – 50 million rubles (around 952 200 euros), and from this fund winner the won 9 million rubles (around 171 396 euros) with transport costs compensated to the club.

”Directors board suggested to decrease the expenses, so we had to find a way to do it with current situation, due to economical sanctions against Russia, and itpotential trigger for fibroblast activation \[[@B3]\]. VEGF was initially named vascular permeability factor because of its ability to promote the extravasation of plasma proteins from blood vessels \[[@B36]\]. Prominent edema of the lower extremity was found in more than 30% of patients with critical limb ischemia after gene transfer of phVEGF~165~\[[@B37]\]. The hypothesis that VEGF might have dual functions in the pathogenesis of SSc, with positive effects on the vascular system but with negative effects on the development of fibrosis, has to be tested in functional studies (e.g. by application of VEGF in animal models of SSc and by careful assessment of both vascular and fibrotic parameters).

The increase of VEGF in patients with the earliest disease stages found in the present study argues for an important role of


VEGF in the pathogenesis of early vascular, and possibly fibrotic, changes. Along this line, levels of VEGF were increased in patients with anti-topoisomerase antibodies and diffuse SSc, which are associated with a more rapid and severe disease course \[[@B38]\]. These results are consistent with findings from Kikuchi *et al*., who showed a correlation of VEGF with the frequency of lung fibrosis and reduced vital capacity in patients with SSc \[[@B39]\]. An important observation of the present study is the development of cutaneous involvement in pre-SSc patients with increased levels of VEGF. Prospective studies with larger patient numbers are needed to confirm this finding. In addition, the classification of patients with Raynaud\'s phenomenon plus nailfold capillary changes and disease-specific autoantibodies as \'pre-SSc\' patients is controversial and might favor patientsmeal unit.
Specifically for food materials having large initial water content, for example, leafy vegetables, reducing its weight to its 1/10 to 1/20 of the initial weight, becoming very light weighted, when dried to remove most of all water contained within. This light weight becomes a barrier against the packaging in a small unit. When a dry product is produced while maintaining the shape, the voids increase while the weight decreases, and a “bulk specific gravity” decreases. This state becomes conspicuous in the case of the freeze-dried product. When the food material of a s mall unit is packaged in this state of condition, it will cause the dried products to float during process of packaging with troubles such as adhesion to the packaging material due to static electricity


considered period.

Co-authorship network analysis: Role of IDCs in the Ebola and Zika epidemics {#sec008}
----------------------------------------------------------------------------

Social network analysis (SNA) of scientific collaborations was pioneered by Newman \[[@pntd.0006469.ref010], [@pntd.0006469.ref011]\]. We used his approach as previously described \[[@pntd.0006469.ref012]--[@pntd.0006469.ref014]\] to investigate the role of IDCs in recent global epidemics.

Network analysis is a theoretical approach that employs a set of techniques used to understand and quantify the relationship between members of a network (nodes), which can be individuals, institutions, countries etc. \[[@pntd.0006469.ref015]\]. By analyzing and quantifying the social structure of a network that is embedded in its nodes and connections, it is possible to assess different perspectives on the importance of individual nodes. In this work, we used the 'betweeness centrality' indicator to identify key countries that are frequently on the shortest paths betweenresults and rankings (Supporting Information [S2 Table](#pntd.0006469.s002){ref-type="supplementary-material"}). As we are particularly interested in the country residence of the patent applicant and in the income generated by the residents of that country, we adopted GNI per capita as the default. Secondly, using specific patent classes in the calculations, therefore selecting and delineating areas of technology or products of interest, allowed the detection of those countries that are more active in a given "product space" \[[@pntd.0006469.ref019]\].

[Table 1](#pntd.0006469.t001){ref-type="table"} displays the comparison of the 25 top innovative countries ranked as described in the original 2005 paper (first country column) and in this study (third country column). The second country column is an update of the first one using USPTO 2015 patent information. To demonstrate the potential and flexibility of our approach, the


of R&D capability by the public and private sectors; (vi) Development of international trade systems for health products, including global procurement funds. Because these innovation components are dynamically linked, successfully developing and introducing new technologies requires concerted attention to each of the six components \[[@pntd.0006469.ref022], [@pntd.0006469.ref023]\]. Using this framework, Morel et al analyzed the progress of developing countries in innovation capability and identified three intermediate stages before reaching a similar development level of industrialized nations \[[@pntd.0006469.ref002]\].

NTDs represent an enormous health burden for developing countries which only recently have been recognized as a global challenge meriting global efforts and commitments from public and private sectors \[[@pntd.0006469.ref025], [@pntd.0006469.ref026]\]. In order to investigate whether NTDs represents a priority for the research and technological development agenda of the top innovative countries rankedother words they not only occur in the setting of poverty, they actually promote poverty \[[@pntd.0006469.ref051]\]. This shift from a passive definition (neglected by someone else) to an active one (poverty promotion) brought the NTDs to the center of the developing countries' social and economic development agendas, forcing the health and science and technology systems of IDCs to play a more endogenous, autonomous and active role in NTD control and prevention \[[@pntd.0006469.ref003]\], instead of just waiting for medical solutions developed abroad, which was the main paradigm of the last century \[[@pntd.0006469.ref052]\].

[Fig 2](#pntd.0006469.g002){ref-type="fig"} shows that IDCs invest above the average on NTDs in a critical component, or determinant, of health innovation: research and development \[[@pntd.0006469.ref002], [@pntd.0006469.ref022], [@pntd.0006469.ref023]\]: Seven of the nine countries prioritizing NTDs R&D, are IDCs: Brazil, Thailand,


Argentina, Indonesia, India, Mexico and Malaysia. The two industrialized countries that this study demonstrated that are also part of this top group, Singapore and Switzerland, have built and run two institutions fully dedicated to R&D on NTDs: the Novartis Institute for Tropical Diseases (NITD) in Singapore and the Swiss Tropical and Public Health Institute (Swiss TPH) in Basel.

IDCs and the prevention and control of epidemics {#sec017}
------------------------------------------------

Another important conceptual paradigm shift that continues to evolve is the focus "from neglected diseases to neglected populations" \[[@pntd.0006469.ref053]\]. We used this point of view to analyze the role of IDCs and their institutions in two recent sanitary crises that impacted neglected populations in Africa and South America between 2014-2016: the Ebola epidemics in West Africa and the spread of Zika virus into Mario (from Mario Kart), stands in front of his restauranttoward the back of the square. Over his belly plumped with years of his own tagliatelle all'aglione - a mark of his own kitchen excellence - a stained apron is stretched taut. He beams, and booms: “Buon Natale”.

No menus for us. Instead we let Alessio reel off the daily selection despite the fact it is a very close variation of that of the day before, and the day before that, and that of summer fifteen years ago when we first stumbled upon “Da Vincenzo”.

Bruschetta al pomodoro - nothing like the weak imitations found in theUK, the tomatoes are plump,and bleed their tangy and garlic infused juices into the unsalted bread. And, of course, all is doused in October’s


15 dispatch call controllers (m=15) and 3200 base stations (n=3200). In such a system, there would be 48,000 logical links connecting the dispatch call controllers to the base stations (i.e., 15 dispatch call controllers×3200 base stations). Accordingly, the dispatch call controllers have to track and manage the state of 48,000 logical links. Such tracking and management of logical links consume substantial amount of processing power of the dispatch call controllers. Additionally, when a link goes down for any reason, the dispatch call controller attempts to periodically reestablish connectivity via the link. This further results in additional consumption of processing power of the dispatch call controllers. Furthermore, the large amount of logical links makes it relatively difficult to troubleshoot problems within the frame relay/ATM network.x, -7?
-7
Let n be (-19)/3211*-26 - 3/(-156)*-6. Which is the fourth smallest value?  (a) -0.12  (b) 0.1  (c) -0.1  (d) n  (e) 4
b
Let n = 4237 - 4241. Let p = 2 - -1. Let m = 2 + -1.92. Which is the second biggest value?  (a) p  (b) 4/5  (c) m  (d) n
b
Let f(d) = -120*d + 11128. Let p be f(93). Let y = -0.1 + 0.1. Which is the second smallest value?  (a) 0.3  (b) y  (c) p
b
Let d = 11272.5 + -11273. What is the fifth biggest value in 2, -2, d, 5, -37?
-37
Let k = 1/8 - -3/8. Let f(q) = q**2 + 20*q + 28. Let y be f(-19). Suppose


Skepasto village. During the Operation "Kalavryta" Skepasto village was destroyed by German occupation forces. Three men (3) were executed on December 13, 1943.

The monastery of Agia Laura was destroyed during the Operation "Kalavryta" by German occupation forces on December 14, 1943. At the entrance of the monastery,five (5) monks were executed.

Monument to the Executed of Kleitoria village. Kleitoria was the last village which was destroyed during the Operation "Kalavryta" by German occupation forces on December 14, 1943. Fifteen (15) men were executed and one (1) survived the execution.

Credits: Story

This exhibit was created by the Municipal Museum of Kalavritan Holocaust. For more information visit: www.dmko.gr

Credits: All media

The story featured may in some cases have been created by an independent third party and may not always represent the views of/*
 * libfdt - Flat Device Tree manipulation
 * Copyright (C) 2006 David Gibson, IBM Corporation.
 *
 * libfdt is dual licensed: you can use it either under the terms of
 * the GPL, or the BSD license, at your option.
 *
 *  a) This library is free software; you can redistribute it and/or
 *     modify it under the terms of the GNU General Public License as
 *     published by the Free Software Foundation; either version 2 of the
 *     License, or (at your option) any later version.
 *
 *     This library is distributed in the hope that it will be useful,
 *     but WITHOUT ANY WARRANTY;


the OH group. The Ti-O-Ti bridging oxygen bonds are proton-coordinated at the titanium oxide surface with oxygen from water molecules physically adsorbed on the titanium oxide surface. The peak displayed at 534.2 eV represents oxygen sites located at terminal Ti-OH bonds, for which the hydroxyl groups are chemically adsorbed on the titanium oxide surface. Finally, the peaks at 532.9 and 534.2 eV represent acidic and basic Ti-OH groups, respectively \[[@B19-ijms-20-04080]\]. According to data in [Figure 1](#ijms-20-04080-f001){ref-type="fig"}b, a small population of both acidic and basic Ti-OH groups became present on the surface layer of the titanium alloy after hydrothermal treatment. The cumulative areal fraction of acidic and basic Ti-OH peaks remained small with increasing time of hydrothermal treatment. However, the presence of these peaks represented a strong indication thatConversely, in the aluminols developed on the Al~2~O~3~ surfaces, H-bond donors were relatively strong and acceptors relatively weak. The nature of H-bonds is key in the dual role of a surface as solvent of oxidant. The fundamental difference between the acid character of surface silanols and the basic one of aluminols has important repercussions on the metabolism of mesenchymal cells exposed to different bioceramic substrates. The zeta potential value at homeostatic pH of the Al~2~O~3~ surfaces was +20 mV.

2.2. Mesenchymal Cell Proliferation and Differentiation {#sec2dot2-ijms-20-04080}
-------------------------------------------------------

[Figure 2](#ijms-20-04080-f002){ref-type="fig"} and [Figure 3](#ijms-20-04080-f003){ref-type="fig"} summarize data collected by fluorescence microscopy and other biological assays, and laser microscopy data collected on KUSA-A1 mesenchymal cells exposed to different substrates. These figures also provide statistically data validations. The fluorescence micrographs in [Figure 2](#ijms-20-04080-f002){ref-type="fig"} (nuclei and F-actin


monitored spectral window, the precise frequencies of which as well as their physical origins have been reported in a previous paper \[[@B10-ijms-20-04080]\]. In the case of cells cultured on Si~3~N~4~ substrates, no significant variations in relative intensity when compared with the positive control sample could be observed after 48 h for RNA/DNA-related Bands 5 (at 783 cm^−1^), 6 (at 794 cm^−1^), and 7 (at 813 cm^−1^). These bands represented vibrations of phosphodiester symmetric stretching in DNA, ring breathing in cytosine, and phosphodiester symmetric stretching in RNA, respectively \[[@B25-ijms-20-04080],[@B26-ijms-20-04080],[@B27-ijms-20-04080]\]. An exception among nucleic acid related bands was Band 8 (out-of-plane ring breathing in tyrosine \[[@B28-ijms-20-04080]\]), which showed a clear decrease of approximately 20% in relative intensity in the spectrum collected on cells exposed to Si~3~N~4~ substrates in compared withthe reduced intensity of Band 2, to approximately a third of that of the control cell sample, and its shift toward lower frequencies can be interpreted as the spectroscopic fingerprints of deprotonation from -NH~3~^+^ to -NH~2~ in the serine group of the phosphatidylserine lipid structure of the cell membrane. Under the effect of alkaline phosphatase, calcium concentration increases in the cytoplasmic space, and Ca^2+^ ions binds to the COO^−^ terminus of the deprotonated serine residue forming Ca complexes \[[@B37-ijms-20-04080]\]. Regarding the effect on other membrane lipids, the disappearance of the phosphatidylinositol Band 9 relates to the interaction between nitrogen radicals eluted from the Si~3~N~4~ substrate and the phosphate group of the inositol structure via transfer of H^+^ protons. Conversely, the structure of phosphatidylcholine (represented by Bands 1 and


will be discussed in detail in the next section.

3. Discussion {#sec3-ijms-20-04080}
=============

3.1. Off-Stoichiometric Reactions at the Cell--Substrate Interface {#sec3dot1-ijms-20-04080}
------------------------------------------------------------------

[Figure 6](#ijms-20-04080-f006){ref-type="fig"} shows schematic drafts of the free surface of the investigated substrates and the set of off-stoichiometric reactions involved with their embedment in an aqueous solution.

The drafts and the reactions listed in the figure are based on the results of accelerated tests in water vapor provided in [Section 3.1](#sec3dot1-ijms-20-04080){ref-type="sec"} and works published by these and other authors \[[@B41-ijms-20-04080],[@B42-ijms-20-04080],[@B43-ijms-20-04080],[@B44-ijms-20-04080],[@B45-ijms-20-04080],[@B46-ijms-20-04080],[@B47-ijms-20-04080]\]. The behavior of Si~3~N~4~ bioceramic is described in [Figure 5](#ijms-20-04080-f005){ref-type="fig"}a,b. In aqueous solution, the surface lattice of this non-oxide ceramic is subjected to dissociation of its Si-N covalent bond. Such a homolytic bond cleavage liberates nitrogen ions to the environment, creates a nitrogen vacancy V~N~^3+^, and exposes silicon sites on the free1D Wigner molecules. [@k1/2; @shulz; @safi; @sablikov; @bortz]\
Other models for 1D fermions map onto a Luttinger liquid in their low-energy sector. The Hubbard model, for instance, can be mapped onto a Luttinger liquid, [@k1/2; @bortz] with $g_{\rho}\geq
1/2$, while $g_{\sigma}=1$ due to SU(2) symmetry. The extended Hubbard model removes the constraint on $g_{\rho}$. [@k1/2] Models for Wigner molecules consisting in anti-ferromagnetically coupled electrons oscillating around their equilibrium positions map [@fiete1; @glazman1; @glazman2; @075; @fiete2] into a Luttinger liquid with $g_{\sigma}=1$.\
The Luttinger model suffers some drawbacks. One is connected to the terms oscillating at wavelengths shorter than $\lambda_{F}$ in the series of harmonics [@haldane] of its electron density. In general, the amplitudes of these terms are model-dependent and are then free parameters. [@safi] When including in the model terms describing Wigner oscillations, indeed all the amplitudes


\[fig:traverso6\] show the linear conductance for $g=0.3$ and the transitions $5\leftrightarrow 6$ and $12\leftrightarrow 13$ respectively. Panels (a) and (b) show the Wigner and the Friedel contributions to the conductance. While the Friedel corrections follow the pattern discussed above, Wigner corrections exhibit a shorter wavelength with precisely $N+1$ maxima and $N$ minima, double the number of those observed in the Friedel case. The position of the conductance peak in the Wigner case follows the position-dependent correction to the chemical potential $\delta\mu^{W}(x_{0})$ defined in Eq. (\[eq:deltamuW\]). Friedel and Wigner corrections induce therefore oscillatory patterns with very different wavelengths, allowing to distinguish the two mechanisms in a non-ambiguous way. Although we have shown the two contributions separately, it can be in general expected that the Wigner and the Friedel mechanisms co-exist.Therefore, in panels (c) we show the conductance in the presence of both perturbations, considering the case of equal amplitudes. Even if here we have chosen the same weights for the Friedel and the Wigner terms ($V_{F}=V_{W}$), the latter impresses its peculiar oscillatory pattern with wavelength $\approx
L/N$ on the conductance peak position. Indeed, as we have already observed in Sec. \[sec:chempot\], when interactions increase the Wigner contribution to the chemical potential becomes even more relevant than the Friedel one. This explains the persistence of $N+1$ maxima and $N$ minima in the oscillations of the chemical potential. Also conductance amplitudes exhibit a pattern reminiscent of the $N+1$ and $N$ maxima and minima but less pronounced with respect to the one shown in the position of the conductance peak.\
Let us now


the tunneling rates to the lowest order in the AFM-dot coupling.\
To discuss the transport properties we have focused on the linear regime, where we have shown that the AFM tip induces a shift of the conductance peak and a renormalization of the conductance strength, which has never been discussed in previous works on this subject. Scanning the tip along the dot allows to observe oscillatory patterns related to both the Friedel and the Wigner oscillations of the electron density. A beating pattern emerges in the linear conductance height oscillations. The Friedel and the Wigner contributions show markedly distinct wavelengths allowing in principle to distinguish the two effects. Surprisingly, we have found that as the interaction strength grows, the effects of the Wigner oscillations on the conductance height vanish,(2006). M. Rontani, C. Cavazzoni, D. Bellucci, and G. Goldoni, [J. Chem. Phys.]{} [**124**]{}, 124102 (2006). A. Harju, H. Saarikoski, and E. Räsänen, Phys. Rev. Lett. [**96**]{}, 126805 (2006). C. Yannouleas and U. Landman, Phys. Rev. Lett. [ **85**]{}, 1726 (2000). A. Puente, L. Serra, and R. G. Nazmitdinov, Phys. Rev. B [**69**]{}, 125315 (2004). U. De Giovannini, F. Cavaliere, R. Cenni, M. Sassetti, and B. Kramer, New J. Phys. [**9**]{}, 93 (2007). U. De Giovannini, F. Cavaliere, R. Cenni, M. Sassetti, and B. Kramer, Phys. Rev. B [**77**]{}, 035325 (2008). F. Cavaliere, U. De Giovannini, M. Sassetti and B. Kramer, New J. Phys. [**11**]{}, 123004 (2009). S. M. Reimann and M. Manninen, Rev. Mod. Phys. [ **74**]{}, 1283 (2002). C. Yannouleas and U. Landman, Rep. Prog. Phys.