case). For a rough estimate of the interaction rate among stars, we use the typical values for open clusters. In their work, Laughlin & Adams (1998), calculate the interaction rate for the Trapezium cluster, using a central density of $n_0 \approx 5\times
10^4$ pc$^{-3}$ and a velocity dispersion of a few km s$^{-1}$, and an interaction cross section of 100$^2$ AU$^2$, obtaining a rate of interaction of one encounter every 40 million years. Considering open clusters live for at least 100 million years, it is expected these interactions are significant in those environments. In the case of the Sun’s birth cloud several observables, such as the inclinations of Uranus and Neptune (which are sensitive to stellar interactions) place densities at similar amounts of typical open clusters, this is $\sim
3\times2.62 mg/g db in *P. vulgaris* L. ([Table 1](#molecules-25-01464-t001){ref-type="table"}). The germination process increased by 73% condensed tannins, independently if germinated beans were lyophilized or oven-dried. Rusydi, et al. \[[@B28-molecules-25-01464]\] reported a 28% and 64% reduction in the tannin content of soy and peanut, respectively, after germination.

Saponin content increased from 7.05 to 9.37 mg diosgenin eq/g of the sample due to the germination process. The drying method did not modify saponin content ([Table 1](#molecules-25-01464-t001){ref-type="table"}). Paucar-Menacho, et al. \[[@B29-molecules-25-01464]\] reported similar initial content of saponins in soybean (7.4 mg/g), and depending on the germination time; saponins varied from 6.7 to 23.5 mg/g. The increase in saponin content during germination could be due to the synthesis and activation of different enzymatic systems responsible for the production of secondary metabolites, the weakening,


et al. \[[@B33-molecules-25-01464]\] reported a 97% reduction in trypsin inhibitors after soaking and cooking of chickpea.

Carbohydrates account for 55% to 65% of the legume grain (Hangen and Benkini, 2002), being oligosaccharides the more abundant after starch. In this study, the most abundant oligosaccharide was stachyose, with content around five times the one of raffinose and verbascose ([Table 1](#molecules-25-01464-t001){ref-type="table"}) in BTN. After germination, raffinose content was increased up to 28.95 mg/g, while stachyose decreased by 41% and verbascose was not detected.

2.2. Effect of DIC on the Non-Nutritional Compounds of Black Bean Sprouts {#sec2dot2-molecules-25-01464}
-------------------------------------------------------------------------

Among secondary metabolites, phenolics are remarkable because of their biological activity, for instance, antioxidant, that is why that independently of the process, phenolics should not change their concentration.

[Table 2](#molecules-25-01464-t002){ref-type="table"} shows the content of non-nutritional compounds in blacksprouts dried at 50 °C and treated by DIC. Phenolics did not show a tendency, although DIC treated samples are significantly different from BGD; some DIC treatments increase the phenolic content slightly, while others did the contrary. DIC treatment involves the application of steam to sprouts; the temperature in the processing chamber could reach 100--120 °C. Changes in phenolics during DIC treatment were related to both, temperature and pressure, and their quadratic effect, as well as the interaction of these factors as shown in [Figure 1](#molecules-25-01464-f001){ref-type="fig"}A.

Alonzo-Macías, et al. \[[@B34-molecules-25-01464]\] and Gahler, et al. \[[@B35-molecules-25-01464]\] reported that DIC treatment modifies the structure of biological material, causing the opening of cellular structures, making phenolics more available, and then an increase in phenolics concentration could be observed. Moreover, Stewart, et al.


high values of trypsin inhibitors and low values of raffinose. In the second one, black bean sprouts dried either by convective air at 50 °C or lyophilized are grouped, indicating that there is no difference related to the drying method. Besides, BGL and BGD presented average values of TIA and raffinose, the responses related to PC1.

Finally, all DIC treated samples were grouped at the left side of PC1. TIA values related with this group were low, while raffinose ones were high. The separation in three well-differentiated groups indicated that all DIC treatments were different from germinated and also from non-treated beans.

3. Materials and Methods {#sec3-molecules-25-01464}
========================

Black bean seeds (*Phaseolus vulgaris* L.) were obtained in a local market of Mexico City. All reagents used were analytical grade from Sigma-Aldrich (St.Louis, MO, USA) and J.T. Baker (Phillipsburg, NJ, USA).

3.1. Germination {#sec3dot1-molecules-25-01464}
----------------

Germination process was realized as described by de Cortes Sánchez, et al. \[[@B46-molecules-25-01464]\]. Seeds were selected according to their size, color, and absence of damage. Before germination, seeds were washed and disinfected with 10% NaOCl for 10 min and washed with water (four times, 10 min). Disinfected seeds were spread on trays covered with humid filter paper (Whatman, 50 × 50 cm), incubated at 23 ± 2 °C for 7 days ([Figure 9](#molecules-25-01464-f009){ref-type="fig"}A) into a germination chamber (Thermo Scientific 3110, Waltham, MA, USA) under environmental controlled conditions (22 °C and in darkness). Watering of the seeds during germination kept the paper always wet. Sprouts were separated into two batches; the first one was lyophilized (−48 °C/1.3 mBar. Labconco


for the scholarship provided.

**Sample Availability:** Samples of the black beans germinated and DIC treated are available from the authors.

Conceptualization, A.C.-M. and C.J.-M.; Data curation, T.G.-V., X.M.S.-C., J.M.-H. and L.J.C.-R.; Formal analysis, A.C.-M.; Funding acquisition, X.M.S.-C., J.M.-H. and L.J.C.-R.; Methodology, A.C.-M., Y.M.-T., T.G.-V., J.M.-H. and L.J.C.-R.; Project administration, C.J.-M.; Resources, T.G.-V. and X.M.S.-C.; Writing---original draft, Y.M.-T.; Writing---review and editing, A.C.-M. and C.J.-M. All authors have read and agreed to the published version of the manuscript.

The present research received no external funding.

The authors declare no conflict of interest.

![Effect of temperature and pressure over the content of Phenolics (**A**): Pareto Chart. (**B**): Response surface. Critical values to obtain the highest phenolic concentration predicted by the model P = 0.17 MPa, t = 13.79 s. Phenolics = 8.03 − 12.71P + 26.39t^2^ 1.96 ± 0.07 \*   8.32 ± 0.04 \*    24.40 ± 0.13 \*
  DIC4        0.10       45     6.63 ± 0.04 \*   14.19 ± 0.17 \*   3.10 ± 0.15 \*   8.22 ± 0.07 \*    49.62 ± 0.1.2
  DIC5        0.27       70     8.29 ± 0.07 \*   15.99 ± 0.22 \*   2.11 ± 0.09 \*   10.99 ± 013 \*    2.20 ± 0.07 \*
  DIC6        0.27


  66.04 ± 0.25 \*   36.10 ± 0.28 \*   102.14 ± 0.15 \*
  DIC3        0.20       45     68.70 ± 0.77 \*   29.50 ± 0.39 \*   98.20 ± 0.21 \*
  DIC4        0.10       45     69.53 ± 0.17 \*   27.74 ± 0.13 \*   97.27 ± 0.90 \*
  DIC5        0.27       70     82.21 ± 0.39 \*   21.22 ± 0.43 \*   103.43 ± 0.60the enantiomers of MQ and its five metabolites is hampered by the difficulty in separating MQ and 4'OH-MQ, the major urinary metabolite. A two-step solid phase extraction process is shown to permit discrimination between these two compounds and thus analysis of MQ enantiomers in unhydrolyzed urines that were collected overnight after administration of 250 mg of racemic MQ. Furthermore, analysis of liquid/liquid or solid-phase extracts of enzymatically hydrolyzed urines reveals the distribution of the enantiomers of the five hydroxymetabolites of MQ and, for the first time, insight into the stereoselectivity of the MQ metabolism. The major metabolite, 4'OH-MQ, is shown to be excreted almost exclusively as single enantiomer. The two urinary enantiomers of 6OH-MQ are present at about equal amounts, whereas unequal amounts are noted for the enantiomers


to
the top of some imaginary ladder of success. Someone who takes an undemanding
job because it affords him the time to pursue other interests and activities
is considered a flake. A person who abandons a career in order to stay home
and raise children is considered not to be living up to his potential ― as if
a job title and salary are the sole measure of human worth. You'll be told in
a hundred ways, some subtle and some not, to keep climbing, and never be
satisfied with where you are, who you are, and what you're doing. There are a
million ways to sell yourself out, and I guarantee you'll hear about them.

To invent your own life's meaning is not easy, but it's still allowed, and I
think you'll be happier for the trouble._

~~~
david927
That'sTubs

Notable people
Tim Armstrong, musician and lead singer of Rancid and Operation Ivy
Anna Baltzer, activist
Mauricio J. Mixco, linguist, researcher of indigenous and endangered languages and emeritus professor from the University of Utah.
Walter De Maria, sculptor
Matt Freeman, musician and bassist of Rancid and Operation Ivy
Edi Gathegi, actor
Tyson Griffin, UFC fighter
Ron Hansen, former Major League Baseball player
Lil B, rapper, artist
Lil Debbie, rapper, artist
Ron Silliman, poet
Angel Tompkins, actress

See also
 Marin Creek
 Albany Hill

References

External links

Category:1909 establishments in California
Category:Cities in Alameda County, California
Category:Cities in the San Francisco Bay Area
Category:Incorporated cities and towns in California
Category:Populated places established in 1909
Category:Populated coastal places in California


@OdaSas09]. We can take $$\begin{aligned}
W_{1+}(x,\ell,m)&=&\omega x\frac{L_{\ell-1}^{(-m-1/2)}\left(-\frac{\omega x^2}{2}\right)}
{L_{\ell}^{(-m-3/2)}\left(-\frac{\omega x^2}{2}\right)}
\label{ex6Wp}\\
W_{1-}(x,\ell,m)&=&\omega x\frac{L_{\ell-1}^{(-m+1/2)}\left(-\frac{\omega x^2}{2}\right)}
{L_{\ell}^{(-m-1/2)}\left(-\frac{\omega x^2}{2}\right)}
\label{ex6Wm}\end{aligned}$$ where now $L_\ell^{(\alpha)}(x)$ denotes the $\ell$-th (associated) Laguerre polynomial. With the identifications above it is readily checked that (\[peqcc\]), (\[cc\]) are satisfied. Likewise, (\[ih\]) is satisfied with $a=0$ and $b=-\omega$, and (\[ccin\]) is also satisfied. This example leads to a pair of Shape Invariant partner potentials which are non-singular since the roots of the Laguerre polynomials of the denominators above lie in $(0,\infty)$, and we have taken explicitly negative arguments in them by means of $-\frac{\omega x^2}{2}$, see also [@OdaSas09].

Conclusions and outlook
=======================

We have demonstrated, in a general way and by means of examples, the validity of the equivalence of the compatibility conditions (\[peqcc\]), (\[cc\]) with the group theoretical condition (\[ccin\]). Thus both approaches are linked in amankind or with any animal" is not only beyond unnecessary, it risks being declared unconstitutional, as anti-sodomy laws have already been declared. It's like a Reese's Peanut Butter cup, except instead of chocolate you have sexuality-based hatred, and instead of peanut butter, you have ... oh, we'll stop now.

What were they smoking?

In March, a zoning ordinance to regulate Detroit's medical marijuana dispensaries goes into effect, barring shops from operating within 1,000 feet of schools, arcades, parks, party stores, child care facilities, churches, public housing, and other dispensaries. The problem? That leaves few parcels city available to consider opening a business and tapping into Michigan's budding marijuana industry. As a cursory glance at the city's Medical Marijuana Caregiver Center Eligibility Search Engine reveals, the ordinance creates wide swaths of


    else
                    rZ = p.z + (hoverRange - j);
                if (rX < 1 || rZ < 1 || rX > BattleFieldManager.GetInstance().GridX - 1 || rZ > BattleFieldManager.GetInstance().GridY - 1)//超出边界的不创建  由于A*报数组下标越界（因为要检测一个单元周围的所有单元，而边界单元没有完整的周围单元），所以这里把边界缩小一圈。
                {
                    continue;
                }
        null, 0);
        //不计算受击角度。
        //o.GetComponent<Animator>().SetFloat("HitAngle", Vector3.SignedAngle(o.position - character.position, -o.forward, Vector3.up));
        o.GetComponent<Animator>().Play("GetHit", 0, 0.2f);
    }

    //后处理附加效果
    protected override void PostEffect(Transform o)
    {
        var damageMP = 1;
        var currentMp = o.GetComponent<CharacterStatus>().attributes.Find(d => d.eName == "mp").value;
        //DebugLogPanel.GetInstance().Log(damageMP.ToString() + " MP" + "（" + character.GetComponent<CharacterStatus>().roleCName + " -> " + o.GetComponent<CharacterStatus>().roleCName + "）");
        var mp = currentMp - damageMP;
        ChangeData.ChangeValue(o, "mp", mp);


and encouraging words of other women. It is a resource men lack. If they do not have an understanding wife or girlfriend, their emotional buckets stand empty.

I have said this often enough on this blog—that women are the one and only emotional stand-in for men in most cases. Even your husband’s best friend isn’t going to be capable of much more than a pat on the back, followed by, “Hey, how about we go for a ride?”

A male friend said to me recently, “For men, emotional sustenance is supposed to be provided by a beer and a football game.”

But when beer and sports don’t cut it, the lucky few with loving women in their lives will come limping and sheepish to our arms, beating around the bush for“I get so bitchy when he’s needy.”

It’s not that we are angry at our husband’s or boyfriend’s failure to be an invincible knight in shining armor. Most of us are realists, and we do not expect men to fight off their dragons all on their own. We don’t think men in emotional need are weak. In fact, when we first fall in love, we find this sensitivity about them wonderfully endearing.

But sometimes, we do resent his deep emotional dependence on us, a dependence we do not share because we usually have female friends and relatives who tend to our emotional bucket filling long before the man in our life ever shows up with a water hose. By day’s end, we have often already been hosed down, dried off,


the spotty-type was not significantly different among all subjects examined (3.6-4.5%). The epitope for the homogeneous-type is likely to be a glycoconjugate since binding of this antibody was abolished after periodate oxidation. The epitope for spotty-type antibody is considered to be a peptide since it was trypsin sensitive. Patients who were positive for the homogeneous-type were also positive for islet cell antibodies, although their antibody titers were not correlated. We conclude that (1) adrenal medullary antibodies are of homogeneous-type or spotty-type and the antigenic determinants of these antibodies are different, and (2) the prevalence of the homogeneous-type is significantly higher in newly diagnosed Type 1 diabetic patients and its presence is associated with that of islet cell antibodies.Kailyn seethes. But when Jordan dumps her and Joe rejects her, there still isn't much sympathy remaining.

The only thing sloppier than Kailyn's behavior is Leah's hasty divorce. Corey handles the situation stoically, taking off his wedding band and quietly letting Leah move her belongings out of their home. Meanwhile, Leah is all tears and dramatics -- saying she's "in shock over everything" and is upset about "being married and divorced in 6 months." Well ... why did you cheat on Corey? And why did you file for divorce?

Jenelle is at rehab in California, where she has some moments of significant self-discovery. "My mom... me and her argue all the time, constantly -- and it's always in front of Jace," she says.

We also learn that Jenelle has a brother


simulation of joy and the actual presence of joy cannot always be distinguished with certainty[24], but the presence of joy on the faces of children specifically seems to be beyond doubt insofar as they have not fully acquired the malignity that comes with a mocking demeanor.

Yet strikingly the love of feasts apparently goes hand in hand with the love of happy faces: “parmi tant de visages gais, je suis bien sûr qu’il n’y a pas un cœur plus gai que le mien” (171). As the ninth promenade reveals explicitly, the most enjoyable feasts are the little ones that Rousseau can himself procure for children. When Rousseau gets the opportunity to purchase some apples from a little girl—who, we are told, guards them like a dragon hoarding its treasure—hethe Dialogues indicates—that J.J. simply has to separate himself from society in order to rid himself of the negative effects of hateful gazes. This accords well with the conception of the state of nature in which the ongoing comparisons induced by amour-propre lead feelings of revenge, inequality, exclusion, etc.

[13] A good example of this can be found in the first part of Dostoevsky’s Notes from Underground. Describing a certain incredulity towards the form of autobiography itself, the underground man remarks:

can one be perfectly honest with oneself and not be afraid of the whole truth? Apropos of this I would point out that Heine claims that true autobiographies are almost impossible and that a man will most certainly lie about himself. In his opinion, Rousseau, for example, undoubtedly lied


why Rousseau prefers to spectate rather than participate in feasts himself.

[24] Perhaps this is why Rousseau complains in L’Essai sur l’origine des langues that French lacks both the vocative and a typographical way of indicating irony: the former would make it possible to indicate the invocation of direct speech that would occur in a face-to-face conversation, whether present or absent; on the other hand, the lack of the ability to indicate irony explicitly through some sort of mark or trace allows all the better for ‘méchants’ to disguise their amour propre by masking it ambiguously as something else. This equivocation of irony and the vocative is obviously only present in writing, although the former can be disguised by the omission of accentual changes. Cf. the note in L’Essai.loci VNTR-A, VNTR-B, and VNTR-C, respectively. Considering the allele combination exhibited by each strain allowed defining 15 genotypes, ending in a discriminatory index of 0.94. Comparison with MLST revealed that both methods were complementary for strain typing in C. maltaromaticum.


A practical 16-day desensitization protocol in lenalidomide-induced non-immediate hypersensitivity reactions.
Desensitization in immediate-type hypersensitivity reactions (HRs) caused by chemotherapeutics is well described and standardized for many drugs. However, there are no standardized protocols in non-immediate HRs. To evaluate the effectiveness of a 16-day desensitization protocol in the non-immediate HRs induced by lenalidomide. According to our previously published slow desensitization protocol, we desensitized patients who had experienced non-immediate HRs attributable to lenalidomide. The protocol was started with the 1/100 of the daily-prescribed dose in milligrams of the culprit drug; then the doses were slowly increased to complete the procedure in 16 days. Demographic and clinical features of the patients were further appraised. Ten patients (mean age was 64.7 ± 10.8 years; 7 male) were successfully desensitized to lenalidomide. The meanin welfare offices "scumbags" and "animals" - rather than the posting of the picture.

Bachmann himself issued an apology over the nature of those posts. "I am sorry that I have damaged the interests of our movement in this way," said Bachmann. "I sincerely apologize to all citizens who feel offended by my posts," said Bachmann."They were imprudent remarks that I would not make today."

Bild quoted Bachmann saying he posted the Hitler picture to coincide with the 2012 audiobook release of a satirical book that imagined the dictator coming back to life in modern-day Germany. "One has to be able to make fun of oneself," Bachmann was cited as saying.

'Either an idiot or a Nazi'

After Bild's publication of the picture, PEGIDA - which has staged a series of increasingly


live objects which are still reachable.

A:

It looks like gc.get_objects is what you want. Be careful using DEBUG_LEAK as it implies DEBUG_SAVEALL. DEDUG_SAVEALL causes all unreferenced objects to be saved in gc.garbage rather than freed. This means the number of objects tracked by the garbage collector can only increase. Additionally gc.get_objects does not return all currently live objects, as some types are not tracked by the garbage collector (atomic types are not tracked). For instance, [i for i in range(1000)] will only increase the objects tracked by one as the integers are not tracked by the garbage collector. Whereas, [[] for i in range(1000)] will increase the number of objects tracked by 1001.

to trigger recognition of injury in the initial stages of the wound defense and repair response. Recent data from studies performed on pulmonary microvascular endothelial cells and isolated perfused rat lungs confirm the role of endothelial responses to stretch-inducing VILI \[[@B13]\]. High tidal volume ventilation (HVV) may induce focal adhesion formation and recruit leukocytes on the endothelial cells \[[@B14]\]. Haseneen and colleagues \[[@B13]\] demonstrated the existence of a connection between stretched endothelial cells and lung remodeling by release of matrix metalloproteinases (MMPs) activated through a membrane type-1 MMP (MT1-MMP) mechanism. The first evidence suggesting that MMPs are important in regulation of endothelial permeability was revealed by Soccal and co-workers using a lung ischemia/reperfusion (I/R) model \[[@B15]\]. Furthermore, it has been shown that inhibition of MMP-2 and MMP-9 protects


levels due to VILI should provide new insights into the mechanisms involved in lung damage. Furthermore, it should lead to the development of novel therapeutic strategies as well as in establishment of more precise and sensitive diagnostic markers.

Results
=======

Effect of ventilation on mechanical function of lungs and on gas exchange
-------------------------------------------------------------------------

Since treatment with doxycycline had no effect on either mechanical function of lungs or on parameters of gas exchange in low tidal volume ventilated lungs which were present in high tidal volume ventilated (HVV) lungs, we decided to perform biochemical analyses of lungs from only HVV groups (Figure [1](#F1){ref-type="fig"}). We postulated that HVV should result in changes similar in nature but greater in magnitude as compared to those observed in lungs ventilated with low tidal volume and therefore the observedgels were stained in 0.05% Coomassie Brilliant Blue G in a mixture of methanol: acetic acid: water (2.5:1:6.5, v:v) and destained in aqueous 4% methanol: 8% acetic acid (v:v). Developed gels were scanned with a GS-800 densitometer (BioRad) and the MMP-9 activity was measured using Quantity One measurement software 4.6 (BioRad).

2-dimensional gel electrophoresis (2-DE)
----------------------------------------

After preparing the tissue extract, a protein solution (0.4 mg) was used to rehydrate a dried first-dimension strip (IPG strip, pH 5-8, 11 cm, BioRad) for 18 h at 20°C under mineral oil. Next, the strips were subjected to isoelectrofocusing (IEF) using a BioRad Protean IEF cell apparatus (BioRad) with focusing parameters as follows: step 1: 15 min with end voltage at 250 V; step 2: 150 min with end voltage at 8000 V; step


from each lung extract using Criterion pre-cast gels (8 to 16%) (BioRad) and transferred the protein to a polyvinylidene difluoride membrane (Bio-Rad). Apolipoprotein A-I (ApoA-I) was identified using a rabbit polyclonal anti-ApoA-I antibody (from Santa Cruz Biotechnology Inc.) at dilution 1:200 and a goat anti-rabbit IgG-HRP as secondary antibody (from Santa Cruz Biotechnology Inc.) at dilution 1:4000. Peroxiredoxin II (Prx II) was identified using a rabbit polyclonal anti-Prx II antibody (from Santa Cruz Biotechnology Inc.) at dilution 1:200 and goat anti-rabbit IgG-HRP as secondary antibody (from Santa Cruz Biotechnology Inc.) at dilution 1:2000. Soluble receptor for advanced glycosylation endproduct (sRAGE) was identified using a goat polyclonal anti-RAGE (N16) antibody against the N-terminus of RAGE (from Santa Cruz Biotechnology Inc.) at dilution 1:200 and donkey anti-goat IgG-HRP as secondaryfield which contains information on both, fiber density and direction. The production of new fibers is based on ordinary differential equations coupled with the migratory behavior of the cells. Filters help smooth the trajectories. Appropriate visualization allows a direct comparison of the simulation results with histomorphology. Matches between computed data and their real counterparts indicate that the development of mathematical models is appropriate to describe and forecast the course of DSR. This makes systems biology a stepping stone to improving biomedical research.


of carotid canal dehiscence on either side per child was 12%. Mean cartilaginous Eustachian tube length was 24.5 mm (SD 3.1 mm) and the minimum measured was 14.1 mm. The minimum length measured in a child over 3 years old (n = 65) was 18.1 mm. The mean thickness of bone of the carotid canal was 0.7 mm (SD 0.27 mm). There was a positive relationship between age and Eustachian tube length (Pearson's correlation coefficient = 0.622, p < 0.001). Carotid canal dehiscence in children has a low prevalence. Variation in the length of the cartilaginous Eustachian tube is low but is correlated with age. More research is required to define the indications, safety, efficacy and technical aspects of BET in children.causal relation between the conduct and the damages claimed. Courmier v. Travelers Insurance Company, 486 So.2d 243 (La.App.3d Cir.), writ denied, 489 So.2d 250 (La.1986).
In the instant case, the jury returned the following interrogatory verdict sheet:

*952
                   "JURY VERDICT"
A.   Was the conduct of any of the following a legal
cause of the accident in this case?
1.   Mark K. Fontenot
                 (Yes or No)          _________
2.   Skyla Marks


face. Using the stem as a nose, carve out the eyes and mouth the regular way, or use the method of slicing off the outer thin layer of pumpkin skin as shown in the image below. Use black paint or a heavy-duty black marker to draw in pupils.

11. Make a Smoking Pumpkin

For this pumpkin carving trick, you will need a small tin foil tray, a bottle of deionized water, a bottle of glycerin, four nails, and 3-4 tea light candles. Place the four nails inside the pumpkin to prop the tin foil tray on, then mix together equal parts glycerin and deionized water (creating a solution similar to what is found in fog machines). Place this solution in the tin foil tray and light the tea light candlespublished in 1990 ().

The book explores the rationality of belief in God. In Part, I, Plantinga examines a number of traditional arguments for God's existence and concludes that none is successful. In Part II, he considers and rejects some major arguments against belief in God, including the problem of evil, the paradox of omnipotence, and verificationism. Finally, in Part III, he explores various analogies between belief in God and belief in other minds. He concludes that these two beliefs are in the same epistemic boat: if one is rationally justified, so is the other. Since belief in other minds is clearly rational, Plantinga argues, so is belief in God.

The book has the following chapters:

Part I: Natural Theology
 Ch 1: The Cosmological Argument
 Ch 2: The Ontological Argument


a cover letter addressed to the Graphic Design faculty. Introduce yourself, briefly describe what your major is, and why you are considering a change. You may also wish to reference the accompanying essay and how it supports your application.

If you are an applicant from Integrative Arts and you have begun taking the Graphic Design sequence of approved courses, please check “advanced standing” in Slideroom when applying

Please feel free to contact our pre-minor adviser Joel Priddy with any questions you may have.

The Design Portfolio for Minor Applicants

The minor portfolio will be evaluated by the Portfolio Review Committee which is comprised of graphic design faculty. The portfolio must consist of:

Examples of visual work

Original poster design

Statement of intent

1. EXAMPLES OF VISUAL WORK

Submit three (3) samples of your best work. These piecesthe garage door closes behind us.

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regression analyses showed that an uncorrected sensory deprivation was associated with a significant and independent impairment of mood, self-sufficiency in instrumental activities of daily living and social relationships. Such impairments were not apparent in the subjects with sensory impairments who were using sensory aids. In men with uncorrected sensory impairment the unadjusted 6-year mortality rate was almost twice that of the other two groups, which did not differ from each other. No corresponding differences were detected in women. Multivariate analysis showed that the effect of the sensory aid status on mortality was indirect and mediated through the global physical health status and the social relationships. We conclude that our cross-sectional data demonstrate an association between uncorrected sensory deprivation and a low QOL; such an association was not presentpast this quote from Fair Game by Patricia Briggs. We felt it fitting to include a paranormal romance book, given the disdain that Twilight and its illegitimate offspring, Fifty Shades of Grey, have inspired in the media. I particularly love this postcard because it reminds me of my favourite quote from Shakespeare’s King Lear (Act 4, Scene 1):

As flies to wanton boys are we to th’ gods,
They kill us for their sport.

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Kat Mayo is a freelance writer, podcaster, Twitter tragic, and compulsive reader. Her reviews have appeared in Books+Publishing, and she was the winner of the 2014 RWA Romance Media Award. She believes in happy endings, and kills fairies with glee.


more folks than you might realize.

But no pressure -- we're all in this together... and together, as another among us likes to say, "let's go up to meet our destiny."-30-

About Me

One of global Catholicism's most prominent chroniclers, Rocco Palmo has held court as the "Church Whisperer" since 2004, when the pages you're reading were launched with an audience of three, grown since by nothing but word of mouth, and kept alive throughout solely by means of reader support.

A former US correspondent for the London-based international Catholic weekly The Tablet, he's been a church analyst for The New York Times, Associated Press, Washington Post, Reuters, Los Angeles Times, BBC, NBC, CNN and NPR among other mainstream print and broadcast outlets worldwide.

A native of Philadelphia, Rocco Palmo attended the Universityclamping part is held in a clamping manner.
It has proven to be a problem with both types of clamping apparatus that in each case two components which are separate at least originally, namely the base body and the clamping means, have to be joined together to form a complex article. Moreover, the assembly of the hinge described above and the folding over of the clamping means in an automated process is particularly problematic.


risk-factor for cancer and can be measured by mutagen-induced chromosome sensitivity assay.

Malignant transformation of normal mucosa is associated with genetic changes that affect cell cycle, apoptosis, angiogenesis and telomere length. Telomerase expression results in direct tumorigenic conversion of normal human epithelial cells and fibroblasts. But the exact point in which the telomerase activation occurs, whether it is expressed at the precancerous or in-situ stage or late in the process of carcinogenesis, is not known. So the ability to detect telomerase activity in the oral precancerous lesions may allow detection of oral cancer at an early stage.

Majority of studies using molecular markers have been conducted in the Western countries where the incidence of oral precancers and the risk of malignant transformation is much lesser compared to the Indian population.et al., 1989). The higher the number of chromosome breaks, poorer is the DNA repair competence. For evaluating DNA repair capability, leukoplakia, oral cancer and controls were grouped into hyposensitive, sensitive and hypersensitive based on statistical significance of mean Bleomycin induced chromosome breaks (b/c) values.

*Data Management and Statistical Analysis*

To find the association between the dependent and independent variables, Pearson Chi-square test was used. Logistic regression was used to find the association between the dependent and three independent variables. Malignant transformation risk of the three candidate genomic markers was analyzed for risk estimation by logistic regression procedure. Sensitivity and specificity analysis of independent markers and combination of markers were also done. A p value ≤ 0.05 was considered as statistically significant.

Results
=======

Study was initiated in Regional Cancer Centre, Trivandrum in


September 2005 and patients followed up to March 2014. Out of 400 participants, 254 were males (63.5%) and 146 females (36.5%). Mean age of patients was 54 years (SD 12.7). Three groups included were leukoplakia (n =200), oral cancer (n=100) and the control (n =100).

Significant difference in distribution of ploidy status, telomerase activity and DNA repair capacity among control, leukoplakia and oral cancer group was observed (p\<0.001) ([Table 1](#T1){ref-type="table"}).

When histologic grading of leukoplakia was compared with DNA ploidy (marker 1) lesions with greater clinical severity had higher grades of dysplasia and abnormal DNA content ([Table 2](#T2){ref-type="table"}).

Histologic severity of leukoplakia was associated with telomerase positivity (Marker 2). Greater proportion of telomerase negative cases was found in homogenous leukoplakia ([Table 3](#T3){ref-type="table"}).

When the molecular markers were compared with histological grading ofanalysis, 49% of tongue lesions were aneuploid compared to only 28% in the buccal mucosa and is consistent with study by Islam et al., (2010). In this study, Telomerase positivity (79%) was found to coincide with high risk sites of leukoplakia and the results were statistically significant and in agreement with a previous study (Miyoshi et al., 1999).

Majority (75%) of leukoplakia, that underwent malignant transformation were non-homogenous leukoplakia and the malignant transformation rate of 6.6% in 6-36 months is in agreement with other hospital-based studies (Sankaranarayan and Somanathan, 2002). On histopathological examination 5/12 (42%) had either mild or no dysplasia, 4/12 (33.3%) had moderate or severe dysplasia while 3/12 (25%) had atypia. In the limited series (12 cases) of leukoplakia that underwent malignant transformation in our study, 5/12


reliability and validity of the Thai language translation of the PedsQL™ 3.0 NMM in Thai children with NMD aged 2--18 years. The secondary objective is to evaluate quality of life in Thai children with NMD through PedsQL™ 3.0 NMM. The Thai versions of this questionnaire will be used in both clinical settings (for example to assess the efficacy of treatments such as gene therapy), and in public health, informing national health policy in pediatric NMD towards improving quality of life for children with NMDs.

Methods {#Sec2}
=======

Study design and patient population {#Sec3}
-----------------------------------

This cross-sectional study was performed during August 2016 to March 2017. Children with NMD were recruited from the Faculty of Medicine Siriraj Hospital, Mahidol University Pediatric Neuromuscular clinic. Inclusion criteria were: 1) neuromuscular diagnosis; confirmed by genetic testing, electromyography/nerve conduction3 domains except child self-report for young children (5--7 years) which has only one domain (About my neuromuscular disease). How much of a problem each item has been within the last month is rated using a 5-option scale, with 0 indicating never a problem, and 4 indicating almost always a problem. The self-administered form used for the 5--7 years group uses a 3-point scale consisting of emojis to elicit the level of difficulty (0 with a big smiling emoji = not at all a problem; 2 with an indifferent emoji = sometimes a problem; and, 4 with a sad emoji = almost always a problem). Items are reverse scored and linearly transformed to a 0 to 100 point scale (0 = 100 points; 1 = 75 points; 2 = 50 points; 3 = 25 points; and, 4 = 0 points), with a higher score indicating a


better HRQoL. The translation process was performed after receiving formal approval to do so by Dr. James Varni, the inventory and copyright owner of the PedsQL™. Translation of the PedsQL™ 3.0 NMM into Thai was performed according to linguistic translation guidelines using the forward-backward translation method \[[@CR10]\]. All steps were completed and the final version was accepted by the MAPI Research Institute in Lyon, France on behalf of Dr. James W. Varni.

The PedsQL™ 3.0 NMM Thai version was administered to NMD children and their parent/caregiver separately at the neuromuscular clinic. For studies that assess children's QoL through both children's and parents' perspectives, it is recommended to separate them. We do not let the parents and children to have interaction because parents may influence children's answers \[[@CR11], [@CR12]\]. Ifself-report, only the subscales "Communication" and "About Our Family Resources" were unable to discriminate between the two groups. This may be due to the fact that children with chronic diseases most often do not directly communicate with healthcare professionals, and they often do not have clear insight into family situations. The mean total score was 67.86, and the mean score in each subscale in the child self-report was similar to the findings of a US study \[[@CR7]\] that administered the questionnaire to spinal muscular atrophy patients. However, compared to a previous study conducted in DMD patients, our results showed higher scores \[[@CR2], [@CR5]\]. Differences in patient populations may explain these differences between studies.

With the validated questionnaire, the PedsQL™ 3.0 NMM allows us to follow the changes in health-related


NMM Thai version has good reliability and validity, and that it is a useful instrument for measuring disease specific health-related quality of life in Thai children with NMD. It can also be used as an outcome measurement in both clinical practice and research. Finally, we suggest further study in a larger NMD population from multiple centres to better assess factor analysis.

NMDs

:   Neuromuscular disorders

PedsQL™ 3.0 NMM

:   The Pediatric Quality of Life™ 3.0 Neuromuscular Module

HRQoL

:   Health-related quality of life

ICC

:   Intraclass correlation coefficient

AHCs

:   Anterior horn cells

NMJs

:   Neuromuscular junctions

PedsQL™

:   The Pediatric Quality of Life

SiRB

:   Siriraj Institutional Review Board

SPSS

:   Statistical Package for the Social Sciences

DMD

:   Duchenne muscular dystrophy

CMT

:   Charcot-Marie-Tooth

SMA

:  the only sportsman to have signed up to appear, but he’ll be joined by the likes of musician Paloma Faith and former media executive Janet Street-Porter.

Victoria Coren, Bill Turnbull and Ben Miller round out the celebrities who’ve confirmed that they will join Skinner in the studio to discuss their pet peeves from everyday life.

Room 101, which was revamped and re-launched on BBC1 in January, has proven popular with viewers and regularly entertained audiences of over 3m per episode in the first quarter of 2012.

The show, which began airing in 1994 with Nick Hancock as host, originally ran on the BBC until 1997. It was re-launched in 1999 with Paul Merton at the helm and continued until Merton left the show in 2007.

Its format originally featured one-on-one interviews with


the original Fatal Frame began "relatively soon" after its release. Many players were too scared to finish the first game, so for the sequel, Tecmo shifted their attention to create a more interesting storyline to encourage players to see it through. Despite this, Fatal Frame II was developed with "horror" being the central focus more-so than the "action". Producer Keisuke Kikuchi and director of the Xbox port, Zin Hasegawa, called it "horror that appeals to human imagination", citing how some people get scared when hearing faint sounds in the dark. Kikuchi cited symmetry as a central theme in the story, in that, "tragedies and fear are based on what happens when you tear things apart," such as butterflies and twins.

In creating the horror atmosphere, they considered more closelybutter on the lemons. Place the salmon fillets on top of the lemons and butter. Use the remaining lemon to cut in half and squeeze the juices on top. Once that is done, using the seasonings above or any others you may enjoy sprinkle on top and then add more butter to finish it off. Seal the aluminum foil very well so none of the juices or butter can leak out as it heats up. Bake for about 35 to 45 min at 375. Meanwhile lets begin on the risotto. This is timed almost perfectly to be done at the same time as the salmon. In a saucepan, heat up chicken broth to keep warm. In a separate pan heat up 2 tbsp of the olive oil and


others just as much as ourselves. In a conscious effort to further the limits of creativity or contribute to the betterment of our online or actual communities.

On the other hand, there are some things that are better kept to ourselves. Pictures, comments, or videos incidentally undermining our online image or people’s conception of our values or beliefs. Caution is key when managing individual or corporate social media and networking content. Don’t be afraid to think more than twice before you post. Deferring again to a prominent historical figure let Benjamin Franklin’s words drive my point home, “Remember not only to say the right thing in the right place, but far more difficult still, to leave unsaid the wrong thing at the tempting moment.”

For example, breaking the world recorddied." "I was a prisoner aboard Fort Rozz." "I made your father a promise, that I would take care of his daughter." "My name is J'onn J'onzz." " Astra." " My dear niece." "Did you really think this was over?" "Why doesn't Kryptonite hurt you?" "Kryptonite?" "Is that what you call it?" "It's just like any other dangerous substance." "Shield yourself in the right materials and it becomes harmless." "Afraid of a fair fight?" "I don't want to fight you, Kara." "I've been blaming you for things that happened a long..." "Don't touch me!" "Your mother always said you had the heart of a hero." "I need for you to be a hero, Kara." "It's time for us to be a family again." "You're not my family." "


can't trust them, they could be working with Armstrong." "But we do know someone who has a legal background who might be able to help us." "Don't we, James?" "And this is a completely hypothetical situation?" "Right, because, you know, if we were actually planning on going after the chairman of the board of the company that we all work at, that would just be insanity." "Full-blown, career-ending insanity." "Can we get a warrant to search Mr. Armstrong's office?" "You need something like a paper trail in which Armstrong directly references conspiring against Cat." "Now, so let's say we get that proof." "Then can we stop him?" "Can we get him fired?" "If you can prove Armstrong is colluding against Cat, his CEO, then we're talking corporate wrongdoing."members who are un-American," Waterston said.

"I wonder how many people weren't worried about McCarthy," objected Waterston.

"You know, Charlie, a lot of people might argue that [Daniels] is on a witch hunt," offered Fonda.

"And a lot of people might argue there are witches out there," Waterston countered.

"I'll fire him, Charlie," said Fonda as the musical score got more tense.

And this was largely where episode three concluded.

When you add it all up, HBO and Sorkin have for all intents and purposes recreated Keith Olbermann, one of the most biased, hateful, and factually-challenged commentators to ever appear on television, and allowed him along with his staff to present a far-left view of America absent any regard for the truth.

Federal employees and military personnel can donate to the Media Research Center through


Innovation meets sports car feeling. A study of the new electric sports car Piëch Mark Zero combines typical sports car attributes and innovative technologies with a timeless and attractive body. It's the first of a family of products to be brought to market by Piëch Automotive in the next three years. Its flexible and open vehicle architecture allows the use of a variety of drive systems - like electric drive, hybrid, fuel cell or internal combustion engine. The entirely new type of battery cell hardly heats up during charging and discharging phases; it features a high rate of recuperation and can be charged up to 80% in 4:40 minutes. This means that fast charging takes only marginally more time than filling up a conventional car with petrol.

(Photo: https://mma.prnewswire.com/media/829594/Mark_Zero_rear.jpgact and to change ALA and, indeed, our profession.

Building a participatory culture is a pretty tall order for an organization of more than 57,000 members. I have been puzzling over the possibilities since I became president. Certainly we have to think beyond the traditional structures of committee appointments, elected offices, and occasional task forces. We have to understand how our members connect to the Association before we can provide pathways of action for them.

One of the complaints we hear about ALA is that it is too complex for members to understand how to navigate and engage. Is that true, or do we need that complexity to enable our very diverse members to find their perfect niches of connection? Perhaps our issues are actually that the complex organization is


{
		/* Accumulate the percentage. */
		total += pt[i].pt_pctcpu;
	}

	if (total < 1.0)
 		total = 1.0;
	factor = 50.0/total;

	qsort(pt, nproc + 1, sizeof (struct p_times), compare_pctcpu);
	y = 1;
	i = nproc + 1;
	if (i > getmaxy(wnd)-1)
		i = getmaxy(wnd)-1;
	for (k = 0; i > 0 && pt[k].pt_pctcpu > 0.01; i--, y++, k++) {
		if (pt[k].pt_kp == NULL) {
			pname = "<idle>";
			pidstr[0] = '\0';
			usrstr[0] = '\0';
		}
		else {
			kp = pt[k].pt_kp;
			pname = kp->p_comm;
			snprintf(pidstr, sizeof(pidstr), "%5d", kp->p_pid);
			snprintf(usrstr, sizeof(usrstr), "%8s",
			    user_from_uid(kp->p_uid, 0));
		}
		wmove(wnd, y, 0);
		wclrtoeol(wnd);
		mvwaddstr(wnd, y, 0, usrstr);
		mvwaddstr(wnd, y, 9, pidstr);
		(void)snprintf(pidname, sizeof(pidname), "%9.9s", pname);
		mvwaddstr(wnd, y, 15, pidname);
		mvwhline(wnd, y, 25, 'X', pt[k].pt_pctcpu*factor + 0.5);
	}
	wmove(wnd, y, 0); wclrtobot(wnd);
}

int
initpigs(void)
{
	fixpt_t ccpu;
	size_t len;

	(void) fetch_cptime(stime);

	len = sizeof(mempages);
	if (sysctlbyname("hw.physmem64", &mempages, &len, NULL, 0))
		error("can't get \"hw.physmem64\": %s", strerror(errno));

	len = sizeof(ccpu);
	if (sysctlbyname("kern.ccpu", &ccpu, &len, NULL, 0))
		error("can't get \"kern.ccpu\": %s", strerror(errno));

	len = sizeof(fscale);
	if (sysctlbyname("kern.fscale", &fscale, &len, NULL, 0))
		error("can't getinteractions, using mediating
gauge bosons.
The species of gauge bosons are eight gluons,
W−, W+ and Z bosons, and the photon.
The Standard Model also contains 24 fundamental
fermions (12 particles and their associated
anti-particles), which are the constituents
of all matter.
Finally, the Standard Model also predicted
the existence of a type of boson known as
the Higgs boson.
Early in the morning on 4 July 2012, physicists
with the Large Hadron Collider at CERN announced
they had found a new particle that behaves
similarly to what is expected from the Higgs
boson.
== Experimental laboratories ==
The world's major particle physics laboratories
are:
Brookhaven National Laboratory (Long Island,
United States).
Its main facility is the Relativistic Heavy
Ion Collider (RHIC), which collides heavy
ions such as gold ions and polarized protons.
It is the world's first heavy ion collider,
and the world's only polarized proton collider.
Budker Institute of Nuclear Physics (Novosibirsk,
Russia).
Its


‘stock picking’) and asset allocation

The economic data that StashAway uses to make unbiased, informed,and long-term investment decisions

The StashAway Risk Index and our emphasis on risk-management

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With all of the different investment options available, it can be difficult to determine which portfolio manager should invest your hard-earned money. Here, we’ll give you an inside look into StashAway and explain how our technology and investment strategy set our offering apart from other traditional financial advisors and robo-advisors. More specifically, we’ll discuss how our technology personalises your portfolios, and how it intelligentlywould you like?" " I don't know." "Just a hint." "A keepsake from the professor would be nice." "We can only afford 2 or 3,000 yen." "I'm not sure." "Any good ideas?" "Sure." "I'll think it over." " With your fiancée?" " Alright." "Want to see Mari Iwamoto play violin?" " When?" " Tonight." "I have tickets." "That's nice." "You bought them for me?" "I did." "Really?" "Of course!" "Are you sure?" "I'd better not." "She'll be jealous." " Come on, let's go." " No way." "She won't mind." "I'd rather not." "Your pickles are linked?" "Yes, my blade must be getting dull." ""Mari Iwamoto Solo Violin Recital"" "Good evening!" " Who's there?" " Mr. Somiya?" " Aya?" " Yes." " Good evening." " Come in." "Is Nori


home?" "She will be soon." "Come in." "Sit over here." "Closer." "I visited my sister in Hayama." "I see." "I hear you've been doing well lately." "In what way?" "That you're very busy." "Not so much." "Typists are in great demand, no?" "I'm not a typist." "I'm a stenographer." "Oh, pardon me." "You do English shorthand?" "I do." "Impressive." "Not really." "Yes, it is." "Not short of money then." "Well, the pay's not bad." "I see." "So, your parents aren't nagging you?" "About what?" "To remarry." "No, not for some time." "Knock on wood." "Once was enough?" "What, marriage?" "I wouldn't say that." " What's his name?" " Who?" " Your ex." " Ah, Ken." "Yes, Kenkichi." "Seen him since?" "No, not once." "But if you did?" "I'd"No, I haven't for years." "Not since the war." "Is that so?" "Mr. Somiya!" "So Nori dear, does she look dirty?" "Don't tease me." "What do you think?" "What's dirty, Father?" "It's unclean." "Right, Nori dear?" "We walked so much today." "Aren't you tired?" "I'm not." "Last time I went to Kodai Temple, the bush clover was splendid." "Plans for tomorrow?" "Misako comes for me at 10." "Where are you going?" "You should see the museum." "Sure." "Shall we turn in?" "Yes." "Shall I turn off the light?" "Please." "Father?" "I ignorantly said terrible things to Mr. Onodera." "What about?" "His wife is so lovely." "They make a wonderful couple." "How could I have called them dirty?" "Don't let it worry you." "What I said was outrageous." "He


to do a deal for the past few days after Smyth requested a trade, reportedly with a preference to return to Alberta. An earlier transaction that would have seen forward Gilbert Brule head to California was scuttled, reportedly due to concerns over Brule's health. He dealt with a few injuries the past season, including a concussion.

Smyth joins an Oilers team that is going in a different direction to the one he left in 2007.

"When we left it was the year [after] we went to the cup. We lost Prongs [Chris Pronger] and then it just started to filter on after that," he said. "I see a huge upside. Obviously with the new draftees, Taylor Hall. Really exciting. [Jordan] Eberle. I just see a huge tremendous upside."

Smyth, who hasplayed on the Canadian Olympic team twice and has represented Canada at the World Championships seven times, will bring his own brand of leadership to the young Oilers.

"What I've experienced along the way in my journey is a tremendous amount," Smyth said.

"I've been fortunate and blessed to play on the Olympics a couple times around, the world championships, a run to the Stanley Cup. I've been around the Lemieuxs, the Gretzkys, the Yzermans. I've hung around those type of players and seen what they bring on a consistent basis.

"It's all about how you come to the rink and how you execute as a hockey player. Just how you compete. Sometimes it's not what you say, it's how you act. Just going out and playing and being yourself."

Oilers general


a very long time. We simply don't forget our children just because their physical body is gone. They live on in our hearts for as long as we live. So Arisa, mourn for as long as you need but don't forget to live. She is still living, but through you. Live bravely, even while mourning. Live on, for her sake and try to be happy again one day. I will keep you and Mariko both in my prayers.

*Hugs*

Ellie Toh

Ps: You are a great mama. Don't ever blame yourself for anything. None of this is your fault. And again, thank you for sharing Mariko with us. That child of yours, definitely taught everyone plenty of lessons.She is indeed the child of truth.

Dear Arisa,It was heartbreaking to read this articleYou are very strong and I believed lil mariko is blessed to have you as a mommy. So sorry that it happened. Stay strong. Will email you in a bit

Dear Arisa, my deepest condolences to u. So sorry to know about your loss. Mariko was a lucky bb to hv you as her mom. You are a strong mom and I always follow your status sijce Mariko was borned. it is indeed very hurtful and heart breaking when knows Mariko was left us so sudden. Hope to catch up with you soon after u hv settle down. Yours Sincerely, Tina Fong.

Dear Arisa, I know you would be very exhausted by now so I won't say much.

Just want you to know that, Mariko was a blessing when she was


around and even when she is not around, she will always be blessing you and watching you from above like how she directed assistance to you to settle all issues to come home with you quickly.

Always strive to be positive for Mariko and know she will always be there rooting for you.

Live the life Mariko never get to live and always share it with her :)

Always remember that we are all around and ready to lend you a shoulder to cry on or an ear to listen to anything at all.

Please take time to slowly settle down and most importantly take care of yourself.

The moment you chose to gave life to this baby, you are a strong and loving mom. Thank you for choosing life over death. Thankwe will hold hands again forever.- Parents of Angels -

I am so sorry for your loss. Words can't express how pained i am to hear that you lost your little angel so soon and when you are so motivated as a mother to give the best you could. Please do know that you and Mariko will be in our prayers and we will be supporting you through your journey of recovery.

That grief to death form losing a child is true to every mum whether the child is a fetus, baby or a grown up. And that loss will stay with the mum for the rest of her life. But one story gave me tremendous consolation and encouragement when I was going through a miscarriage recently. I hope it


the most precious being for her...she is there...her little soul is there with you...there is no way we dissapear like that. Be strong my dear...and I am so sorry...Mariko lived a short time, bur she came to this world thank to you...you gave her life...she was happy and loved. You did the your best...you were the best mother. Many hugs from Spain ❤

I'm actually a silent follower of your instagram. I came here as I was shocked to find the saddening news of Mariko on your instagram post. Your post touched my heart; it is full of love and sincerity. I can see that Mariko is such a lucky baby to have a strong, caring, beautiful, and independent mother such as yourself. Please do not give up onPost naming Harward as the front-runner:

Harward served under Mattis while he was at U.S. Central Command and remains an ally and friend of the defense secretary.

The officials said Harward, who has been under consideration as a possible undersecretary of defense for intelligence, is seen by key players around Trump as a steady pick for the post following the tumult that surrounded Flynn.

The officials also described Harward, who had a tour on the National Security Council during George W. Bush’s presidency, where he worked on counterterrorism strategy, as someone who had a high profile in security circles but a low public profile, which is part of his appeal.

Put another way: Harward might be less likely to pick a public fight with the intelligence community. If the “deep state” really


of the developing tissue. Conversely, abnormal ENS development is thought to be associated with situations where the front of cells fails to reach the anal end of the tissue \[[@pone.0138894.ref006], [@pone.0138894.ref007]\].

Previous mathematical models of ENS development involve reaction--diffusion equations on a growing domain \[[@pone.0138894.ref006], [@pone.0138894.ref009]\]. These partial differential equation models have been solved numerically, and the numerical solutions used to investigate the interaction between the rates of cell migration, cell proliferation and tissue growth. The interaction between these processes is of interest as it has been shown that altering the relative rates of cell migration, cell proliferation and tissue growth has an important impact on whether the moving cell front can overcome the effects of tissue growth and completely colonize the growing tissue \[[@pone.0138894.ref006], [@pone.0138894.ref009]\]. Previous analysis ofare visually indistinguishable.

![Comparison of exact and numerical solutions of Eqs ([12](#pone.0138894.e013){ref-type="disp-formula"})--([15](#pone.0138894.e016){ref-type="disp-formula"}) with equal reaction rates.\
Profiles in (a)--(e), (f)--(j) and (k)--(o) show *C* ~1~(*x*, *t*), *C* ~2~(*x*, *t*), *C* ~3~(*x*, *t*), *C* ~4~(*x*, *t*) and *S*(*x*, *t*) at *t* = 0,10, and 20, respectively. Each subfigure shows the exact solution (solid red) superimposed on the numerical solution (dashed blue). This example corresponds to exponential domain growth with *L*(0) = 1, *L*(10) = e ≈ 2.78 and *L*(20) = e^2^ ≈ 7.39, as indicated in each subfigure. The exact solutions are obtained by truncating the infinite series after 1000 terms and the numerical solutions ([S1 Supporting Information](#pone.0138894.s001){ref-type="supplementary-material"}) correspond to *δξ* = *δt* = 1 × 10^−3^. Here we have *L*(0) = 1, *α* = 0.1, 𝓒 = 1, *γ* =


these exact solutions are provided as Supporting Information and these worksheets can be very easily manipulated to explore the effect of varying the level of truncation ([S2](#pone.0138894.s002){ref-type="supplementary-material"} and [S3](#pone.0138894.s003){ref-type="supplementary-material"} Supporting Informations). To demonstrate this, we present additional results in [Fig 5(a)](#pone.0138894.g005){ref-type="fig"} showing $S(x,t) = \sum_{i = 1}^{4}C_{i}(x,t)$ for the same problem considered previously in [Fig 3](#pone.0138894.g003){ref-type="fig"}. The profiles in [Fig 5(a)](#pone.0138894.g005){ref-type="fig"} compare the exact solution truncated after 1, 2, 5 and 1000 terms. Visual inspection of the profiles indicate that the profile corresponding to 1000 terms is indistinguishable from the profile corresponding to 5 terms. In contrast, the profiles corresponding to 1 and 2 terms in the truncated series are visually distinct. To quantify these trends we plot, in [Fig 5(b)](#pone.0138894.g005){ref-type="fig"}, ∣*S* ^exact^(*x*, *t*)−*S* ^truncated^(*x*, *t*)∣, at *x*models is that they can be solved exactly, thereby providing more general insight than knowledge gathered from repeated numerical simulations.

Supporting Information {#sec010}
======================

###### Additional results and discussion.

(PDF)

######

Click here for additional data file.

###### Maple worksheets to calculate exact solution with distinct proliferation rates.

(MW)

######

Click here for additional data file.

###### Maple worksheets to calculate exact solution with repeated proliferation rates.

(MW)

######

Click here for additional data file.

[^1]: **Competing Interests:**The authors have declared that no competing interests exist.

[^2]: Conceived and designed the experiments: MJS JAS LCM REB. Performed the experiments: MJS JAS LCM. Analyzed the data: MJS JAS LCM REB. Contributed reagents/materials/analysis tools: MJS JAS LCM REB. Wrote the paper: MJS REB.


crystallinity of β-Ni(OH)~2~, which may be in favor of enhancing the electrochemical performance[@b36]. In addition, the typical features of graphene can be found in the following Raman spectra, SEM and TEM images.

The Raman spectra of pure Ni(OH)~2~ and the RGO-Ni(OH)~2~ composite are displayed in [Fig. 2b](#f2){ref-type="fig"}. Two prominent peaks at 1349 cm^−1^ and 1603 cm^−1^ in the spectrum of the RGO-Ni(OH)~2~ composite can be attributed to the D and G bands of RGO, respectively. Generally, the G band represents the in-plane bond-stretching motion of the pairs of C sp^2^ atoms (the E~2g~ phonons). The strong D band implies a large number of defects of as-prepared RGO, which mainly results from the weak reduction way. Commonly, the peak intensity ratio of the D and G band can be used to roughlyestimate the disorder degree and average size of the sp^2^ domains of the graphite materials[@b18][@b37]. Thus, the high ratio (I~D~/I~G~ = 1.38) indicates there are a lot of defects of the as-prepared RGO. Moreover, the peaks at 3591 cm^−1^ and 2923 cm^−1^ can be assigned to the characteristic peaks of β-Ni(OH)~2~[@b38][@b39]. The result further confirms that Ni(OH)~2~ has been successfully anchored on the RGO sheets.

The carbon content of the RGO-Ni(OH)~2~ composite can be determined by the TGA technique. [Figure 2c](#f2){ref-type="fig"} displays the representative TGA curves of pure Ni(OH)~2~ and RGO-Ni(OH)~2~ composite. The two samples both show a slight weight change below 230 °C because of the evaporation of adsorbed water molecules[@b40][@b41]. The evident weight loss of pure Ni(OH)~2~ at the temperature range 240--300 °C comes from the decomposition of Ni(OH)~2~ to NiO. Nevertheless, the


pore size distribution (see [Supplementary Fig. S1](#S1){ref-type="supplementary-material"}) of pristine Ni(OH)~2~ shows very thin micropores and mesopores ranging from 1.5 to 2.4 nm, and a small number of macropores in the range of 147--185 nm. Compared to pure Ni(OH)~2~, RGO-Ni(OH)~2~ composite shows wider pore size distribution of 1.5--68 nm and 120--160 nm. These considerable mesopores and macropores can facilitate the rapid migration of electrolyte ions during the charge/discharge process, which is highly crucial for high-performance supercapacitors[@b20][@b37].

The detailed morphology and structural properties of Ni(OH)~2~ and RGO-Ni(OH)~2~ composite are examined by TEM and SEM, as shown in [Fig. 3](#f3){ref-type="fig"} and [Fig. 4](#f4){ref-type="fig"}. As displayed in [Fig. 3a](#f3){ref-type="fig"}, the RGO sheets are quite thin and possess a small number of wrinkles, indicating that they can act as ideal substrates to support the ultra-small Ni(OH)~2~ particles. FromCu-Kα radiation, λ = 0.15405 nm) and Raman spectroscope (JY-HR800, the excitation wavelength of 532 nm) were employed to investigate the morphology and structure of as-prepared electrode materials. X-ray photoelectron spectroscope (XPS, Physical Electronics, PerkinElmer PHI-5702) and Fourier transform infrared spectrometer (FTIR IFS120HR) were employed to examine the chemical species. Thermogravimetry (TG) measurements were performed by a thermo gravimetric analyser (TGA-STA 449C, from 30 °C to 800 °C in air). The nitrogen adsorption--desorption isotherm measurements were performed on a Micromeritics ASAP 2020 volumetric adsorption analyzer at 77 K. The Brunauer--Emmett--Teller (BET) method was utilized to calculate the specific surface area. The pore-size distribution was determined by a nonlocal density functional method using the adsorption data, and assuming a slit pore model.

Electrode preparation and electrochemical measurements
------------------------------------------------------

The working electrodes were fabricated as follows: 85 wt% active material (Ni(OH)~2~,


and prepared the [Figs 1](#f1){ref-type="fig"}, [2](#f2){ref-type="fig"}, [3](#f3){ref-type="fig"}, [4](#f4){ref-type="fig"}, [5](#f5){ref-type="fig"}, [6](#f6){ref-type="fig"}, [7](#f7){ref-type="fig"}, [8](#f8){ref-type="fig"}. Y. H. L. and R. T. W. worked on all experimental works and contributed equally to this work. All authors reviewed the manuscript.

![Schematic illustration of the synthesis process:\
(**a**) the RGO-Ni(OH)~2~ composite and pure Ni(OH)~2~, and (**b**) the enhanced RGO sheets with Ni(OH)~2~ particles as spacers and the conventional RGO sheets prepared by directly thermal treatment.](srep11095-f1){#f1}

![(**a**) XRD patterns, (**b**) Raman spectra, (**c**) TG curves and (**d**) Nitrogen adsorption/desorption isotherms of Ni(OH)~2~ and RGO-Ni(OH)~2~ composite.](srep11095-f2){#f2}

![(**a**) TEM image of the RGO. (**b**) TEM image and the corresponding size distribution of the Ni(OH)~2~ particles. (**c**) TEM image of the RGO-Ni(OH)~2~ composite. Inset shows an annular dark field scanning TEM (ADF-STEM) image of RGO-Ni(OH)~2~ composite. (**d**) High-resolution TEM image of thewith exactly one hour to eat lunch and do their errands, and many of them were complaining loudly about being docked for pay in jobs they desperately need. Hardly a way to win friends and influence people.

Meanwhile, just east of Los Angeles in the college town of Claremont, students from the "Occupy" movement were sending out leaflets for a protest aimed at Condoleezza Rice's appearance at Claremont McKenna College. Condi Rice a war criminal? Not in my book. And what does that have to do with a movement that is supposed to be committed to economic justice and depends on respect for First Amendment freedoms?

Indeed, by the time they were evicted last night, I'm not sure anyone who has paid attention to the signs at Tent City or


that it is merely being fulfilled on his behalf, such delays are not of concern. However, if the customer is placing an order in real time, that is, he is awaiting its completion, the accumulated delays represent a considerable inconvenience or annoyance to the customer and become unacceptable.
There a need therefore exists in the prior art to substantially reduce the delay encountered in provisioning telecommunications services and equipment via a network.
In accordance with one aspect of the present invention, the delay in provisioning telecommunication services and equipment via a network can be reduced significantly by performing substantially all of the provisioning processes sequentially on a single server. That is, through the counterintuitive approach of using sequential processing on a single server rather than parallel processing on a pluralityA Radiant Path

Joined February 2011

Wall Art

Canvas Print

Photographic Print

Art Print

Framed Print

Metal Print

Stationery

Greeting Card

Artist's Description

This was original a very quick (under one hour) digital painting done for a “Sketchfest”—where the public is invited to give simple text prompts to artists and the latter will draw/paint what they may. The prompt that inspired this painting was of course “a radiant path”, and after the initial rough, I took a bit more time to give the painting more detail.

Technical stuff: The original pencil drawing was 5 by 10 inches. The painterly look was achieved digitally using Photoshop and also combined a high-resolution scan of tea-stains, and my own photographs of very textured antique wood.


photometry
and time-series analysis, light curve modeling and stellar astrophysics are
highly desirable. An appreciation for the importance of interface control
documents, configuration management, and system engineering is critical.
[....more at link...]_

<http://www.seti.org/jobs/kepler-archive>

~~~
guelo
I have a feeling the "succeful candidate" already knows and works with many of
the interested people.

------
ANH
Here's a recent Planetary Society podcast interview with the Kepler principal
investigator, Bill Borucki: <http://planetary.org/radio/show/00000400/>

He talks about the discovery of those hundreds of candidate planets.

------
leot
Perhaps it will be related to this?

[http://www.nature.com/nmeth/journal/v6/n7/full/nmeth0709-487...](http://www.nature.com/nmeth/journal/v6/n7/full/nmeth0709-487.html)

EDIT: original PNAS article <http://www.pnas.org/content/106/19/7816>

~~~
anigbrowl
I'd be surprised, but happily we have options for making such tests via Hubble
and others, so if not now, then maybe later.

BTW if you haven't seen it, you'll probably enjoy this (small pdf):
[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.43....](http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.43.1070&rep=rep1&type=pdf)

------
aplusbi
Maybe they discovered a planet that orbits a binary star but whose orbit
doesn't match what physics would predict for planets inRegulatory T cells (T~regs~) play an integral role in the adaptive immune system through suppression of self-reactive immune responses in order to prevent autoimmunity and maintain homeostasis. However, they are deleterious in cancer through suppression of the anti-tumor immune response. In fact, we show that deletion of 50% of T~regs~ results in normal tumor growth. Therefore, it is advantageous to understand the role of T~regs~ in the tumor microenvironment in order to create targeted cancer therapies. Our lab has shown that the Neuropilin-1 (Nrp1) pathway is required for T~reg~ stability in the tumor microenvironment, but is disposable for maintaining immune homeostasis in the periphery, identifying it as a prime therapeutic target.

In order to further understand the role of Nrp1-deficient T~regs~ intratumorally, we constructed a competitive environment by utilizing


Comparison of serial measurements of infarct size and left ventricular ejection fraction by contrast-enhanced cardiac magnetic resonance imaging and electrocardiographic QRS scoring in reperfused anterior ST-elevation myocardial infarction.
Left ventricular ejection fraction (LVEF) is a powerful prognostic marker after acute myocardial infarction and is dependent on infarct magnitude. Contrast-enhanced cardiac magnetic resonance (ceCMR) represents the current criterion standard means of LVEF and infarct size measurement. Infarct size and LVEF can be estimated from the 12-lead electrocardiogram (ECG) using the Selvester QRS score. We examined for the first time the relationship between serial measures of LVEF and infarct size by ceCMR and ECG in patients with reperfused anterior ST-elevation myocardial infarction (STEMI) and depressed LVEF. Thirty-four patients (mean +/- SD age, 59 +/- 11.8 years; 70.6% male) underwent ceCMR andHoldenCAPITAL principal Dan Holden talks with developer and builder Brent Thompson of Siera Group about technological game changers, the new Australian dream and the changing landscape of the development industry.

Siera Group was established in 2014. Since then, they have gained a reputation for exceeding expectations in every aspect of development delivery.

Siera Group residences promote a perfect balance between lifestyle, design and size.

Their developments begin with the identification of a community or location that enables them to imagine a distinctly Siera residence. The project is then carefully designed and moulded around the desires of the end occupants.


globular subunits with accessible surface areas similar to those of monomeric proteins. We suggest that these oligomers assemble from preformed monomers with little change in conformation. In oligomers with large interfaces, isolated subunits should be unstable given their excessively large accessible surface, and assembly is expected to require major structural changes.takes a few minutes for the unit to resume all bodily functions. Once this happens, the corpse is reanimated and is thus brought back to life. To stay operational, the unit has to ensure a sufficient energy flow by food consumption. The subjects controlled by BCU-2 unit are programmed to attack the living convicts and they feed off their flesh until the victim dies and becomes controlled as well. All BCU-2 units are capable of intercommunication via shortwave radio signals within the range of 250m. Depending on the programming, BCU-2 units can perform various bodily actions such as walking, running, jumping, climbing and grasping. To a certain extent, they can even coordinate the limbs to perform complex actions such as wielding a weapon or throwing a rock. If


the unit is fully charged, it may stimulate the body to move faster than a normal human being does, but as its energy runs out, the controlled subjects are slowed down and experience only occasional energy bursts. These subjects are also known as ‘puppets’, ‘spooks’, ’biters’, ‘walkers’, ‘pawns’, ‘roamers’ or ’runners’.

The BCU-2 is capable of broadcasting footage directly from the subject’s eyes and this feature has become extremely popular among the viewers. To be able to experience the very last moments seen by a dying man is an instant hit on television and has helped TEC1 to take reality TV to the next level. The software that controls BCU-2 units can be upgraded from the TEC1 network servers in real-time. There are rumors about new software upgrades allowingcanned food). The newcomers are dressed in standard prison jumpsuits of orange color and provided with parachutes. Once they are delivered to the drop location, they are pushed out of the plane. Most manage to open the parachute and survive the fall. It is not uncommon that the prisoners on the island wait and kill the newcomers when they are in the air, looting their bodies upon landing. It is recommended to activate the parachutes as late as possible to buy some time for an escape out of the drop location. Except for the convicts, the planes also drop supplies for the prisoners on the ground. These can contain anything from food, weapons, ammunition to clothes and gadgets. Sometimes fake booby-trapped supplies are dropped, too. The dropped supplies


transferred only once, from his enlisted battalion (58th) to the 1st Canadian Pioneers, which later became known as the 9th CRT. His paybook and file paysheets list him as a Steam Tractor Engineer & Repairs.

Another wonderful source of information I found was the CEF (Canadian Expeditionary Force) Study Group. Try searching on your ancestor’s battalion to begin with, or just browse.. The amount of accumulated knowledge on this site is formidable.

Finding out what happened on a specific day in the war in a particular battalion is actually quite easy–search on the battalion and read the War Diaries. Almost everyday entries were made describing what the battalion did on that day. Although very few names are specifically mentioned, it can give you a very good overview of what thingsthat $f_{1}$, $f_{2}$ and $f_{3}$ have the property P2 using the modular properties of $\theta_{4,n}(0)$ and $\eta(\tau)$.

\[p4\] We have $
\theta_{6,1}(0)-\theta_{6,5}(0)=\eta(\tau).
$

Lemma \[p4\] is proved by comparing the infinite series expansions of the functions.

The proof of Theorem \[t1\]
===========================

Proof of [[(\[esi1\])]{}]{}
---------------------------

For ${\kappa}=2p+2$, the space of conformal blocks is one-dimensional. The right hand side of [[(\[esi1\])]{}]{} is a solution of [[(\[KZB\])]{}]{} with the properties (i)-(iv) [@FV1]. According to Theorem \[t0\], the left hand side also has these properties. Thus the two functions are proportional. The coefficient of proportionality is calculated by comparing the leading terms of ${\vartheta_{1}}^{p+1}$ and $u_{{\kappa},p+1}$ in the limit as $\tau\to i\infty$. The leading term of ${\vartheta_{1}}^{p+1}$ is $
(-i)^{p+1}q^{(p+1)/8}(e^{\pi i{\lambda}}-e^{-\pi i{\lambda}})^{p+1}$. Let $dt=dt_{1}\dots dt_{p}$. The leading term of $u_{{\kappa},p+1}$ is $$\begin{gathered}
\int_{\Delta_{p}}
\prod_{j=1}^{p}
\left(
\frac{e^{\pi it_{j}}-e^{-\pi it_{j}}}{2\pi e^{\frac{\pi i}{2}}}
\right)
^{-\frac{2p}{2p+2}-1}
\prod_{1\leq j<k\leq p}
\left(
\frac{e^{\pi i(t_{j}-t_{k})}-e^{-\pi i(t_{j}-t_{k})}}{2\pi


same meeting, California representative Brad Sherman criticized the currency. He’s mostly against the project’s ability to “transfer power from the United States government,” which isn’t surprising coming from a member of said government. Sherman believes that this power will then be given to “tax-evaders, terrorists, and drug dealers while reducing the importance of the U.S. dollar as the reserve and trade currency.” A bit of a bold claim, but a notable one nonetheless. “It is time to bring Mark Zuckerberg here,” Sherman concludes.

A Questionable Effect On Bitcoin Price

Regardless of the criticism, it’s hard to say for sure if the congressional meeting broke Bitcoin’s price. Speaking to CNBC by email is one Mati Greenspan, eToro’s senior market analyst. The expert can’t say for sure if traders are paying attentionAnd it has gone nowhere.

But now that Congress is getting to a situation where face-to-face voting could be downright dangerous, it’s possible the centuries-old practice of in-person voting could change. Three members of Congress have tested positive for the virus, and more than two dozen have gone into quarantine after brushes with it, meaning they could miss important votes on bailout packages.

On Sunday, President Trump said he’d support remote voting. Top House Democrats have privately floated it.

AD

AD

In the Senate, there’s a new bipartisan proposal to vote remotely for up to 30 days. Senate Minority Leader Charles E. Schumer (D-N.Y.) has endorsed the idea for an emergency. Sen. Amy Klobuchar (D-Minn.), the top Democrat on the Rules Committee for how the Senate works, said it’s just a matter of


hydrogen, C1-C3 alkyl, substituted or unsubstituted phenyl, or halogen. Most preferably, R17 is hydrogen, methyl, or chloro. R18 may be hydrogen, C1-C6 alkyl, phenyl, carboxy, C1-C6 alkoxy-carbonyl, or C1-C6 haloalkoxycarbonyl. Preferably, R18 is hydrogen, C1-C3 alkyl, phenyl, carboxy, C1-C3 alkoxycarbonyl, or C1-C3 haloalkoxycarbonyl. R19 and R20 may each be hydrogen, C1-C6 alkyl, or phenyl. Preferably, R19 and R20 are each hydrogen, C1-C3 alkyl, or phenyl. Most preferably, R18, R19, and R20 are each hydrogen or methyl. R1-R20 the phenyl substituents may be C1-C3 alkyl and the halogen or (halo) groups may be chloro or bromo.
In graphic formulae IA1, IA2, and IA3, B and Bxe2x80x2 may each be selected from the group consisting of (i) the substituted or unsubstituted aryl groups phenyl and naphthyl; (ii) the substituted or unsubstitutedas naphthopyrans substituted at the 3 position of the pyran ring with (i) an aryl substituent and (ii) a phenyl substituent having a 5- or 6-member oxygen and/or nitrogen containing heterocyclic ring fused at the number 3 and 4 carbon atoms of the phenyl substituent and with a nitrogen-containing heterocyclic ring at the 6 position of the naphthyl portion of the naphthopyran compound. These compounds may be represented by the following graphic formula:
In graphic formula I, R1 may be C1-C10 alkyl, halogen, or the group, xe2x80x94Oxe2x80x94L, wherein L is a C1-C12 alkyl, e.g., methyl, ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, and dodecyl, said halogen being chloro, fluoro, or bromo, and a is the integer 0, 1 or 2. Preferably, R1 is C1-C5 alkyl,


chroman-6-yl; when X is oxygen and Y is oxygen, the unsubstituted group is a 1,4-benzodioxan-6-yl; and when X is nitrogen and Y is carbon, the unsubstituted group is 1,2,3,4-tetrahydroquinoline-6-yl. For brevity, these groups will be referred to herein as fused heterocyclicphenyl groups.
The preferred naphthopyran dye is 3,3-diphenyl-3-H-naphtho[2,1-b]pyran represented by the formula
where R1 to R6 denote hydrogen.
The spiroxazines suitable in the present invention are known: see for instance, U.S. Pat. Nos. 3,562,172; 3,578,602; 4,215,010 and 4,342,668, all of which are incorporated by reference herein. Essentially, the spirooxazines suitable in the present invention may be described by the formula
where:
R1 and R2 independently represent a hydrogen or halogen (fluorine, chlorine or bromine) atom or a group chosen from C1-C5 linear or branched alkyl, C1-C5 perfluoro-alkyl, C1-C5 alkoxy, nitro orgroup;
R3 and R4 each represent the methyl group or jointly represent the cyclohexyl group;
R5 represents the methyl group;
R6 represents a hydrogen atom or the xe2x80x94NR8R9 group where the groups R8 and R9 together with the nitrogen atom to which they are linked form a piperidyl, morpholyl, pyrrolidyl or hexamethyleneimino ring structure; and
R7 represents a hydrogen atom; and
X represents CH.
Examples of preferred photochromatic compounds used according to the present invention are 1,3,3,4,5- or 1,3,3,5,6-pentamethyl spiro(indoline-2,3xe2x80x2-[3H]-naphtho-(2,1-b)-(1,4)-oxazine); 1,3,3-trimethyl spiro(indoline-2,3xe2x80x2-[3H]-naphtho-2,1-b)-(1,4)-oxazine); 1,3,3-trimethyl spiro(indoline-6-(1-piperidyl)-2,3xe2x80x2-[3H]-naphtho-2,1-b)-(1,4)-oxazine; 1,3,3-trimethyl spiro(indoline-6xe2x80x2-(1 -morpholyl)-2,3xe2x80x2-[3H]-naphtho-(2,1-b)-(1,4)-oxazine); 1,3,3,4,5- or 1,3,3,5,6-pentamethyl spiro(indoline-6xe2x80x2-(1-piperidyl)-2,3xe2x80x2-[3H]-naphtho-(2,1-b)-(1,4)-oxazine); and 1,3,3-trimethyl spiro(indoline-6xe2x80x2-(1-piperidyl)-9xe2x80x2-(methoxy)-2,3xe2x80x2-[3H]-naphtho-(2,1-b)-(1,4)-oxazine).
The spiropyrans useful for the purposes of the present invention, are photochromatic organic compounds which can be defined by the following general formulae (II), (III), (IV) and (V):
In the preceding general formulae:
R10 and R11 represent alkyl or aryl groups;
R12 represents


Using LIVE Social Media to Explode Your Brand Awareness. Join Sarah and Josh for a fun and interactive HOW TO demonstration that will create buzz for your brand and have fun along the way!
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New, prospective, or an existing member wanting to learn about maximizing your membership? Register today for this informative and FREE program that will help you best utilize your benefits through the Plano Chamber of Commerce!
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The complex and dated process for funding our public schools has reached a critical juncture. Our expert panel is set to discuss how accountability, taxparency, student outcomes and ‘Robin Hood’ all intertwine and impact your local schools -- and what you can do about it.
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The Public Policy Committee discusses legislation and issues that affect the business community. Attendedwas generally intact in most control subjects, however, we found that the abilities of individuals in the three different patient populations to recognize odors were impaired relative to control subjects. All three types of patients exhibited decreased or impaired odor-recognition compared with age-matched controls. Previous studies showed the causes of olfactory impairments in PD and AD patients were attributable to pathological changes and MRI signal abnormalities in limbic areas, including the amygdala (AMG), entorhinal cortex (ENT), hippocampus (HI), and orbitofrontal cortex (OFC). Another study reported that DM1 patients have bilateral lesions in anterior temporal areas, including the subcortical white matter, AMG, ENT and insula. Our findings underscore the need to pay careful attention to significant decreases of odor identification abilities caused by diverse forms of abnormal brain function,


Q:

Problems recoding variables with strings

Goal
I am attempting to create a categorical (e.g, string) variable in R using values from a different variable, and according to specific criteria.
Problem
This does not seem to actually recode the data. I am transforming the data, but I am not sure in which way.
Description of Data
I have a data frame structured at the country-month unit of analysis. One of the variables is governance, and is continuous. It ranges from 0.750 to 4.333.
Steps Taken
I am attempting to create a categorical variable in which I create labels for 4 different broad groups of governance.
Here is what I tried:
syndromes$syndrome_cat <- NA
syndromes$syndrome_cat[syndromes$governance <= 1.645] <- "Category 1"
syndromes$syndrome_cat[syndromes$governance >= 1.646 & syndromes$governance <= 2.541] <- "Category 2"
syndromes$syndrome_cat[syndromes$governance >= 2.542 & syndromes$governance <= 3.437] <- "Category 3"
syndromes$syndrome_cat[syndromes$governance >= 3.438] <-\ \mbox{ and } p_{wv} =1 \Big\} .$$

See Figure \[figure2\] for the construction of ${\mathsf{M}}_\mu$. By construction, any capacity $\mu  \in \mathrm{Cap}([0,1]^d)$ satisfies $\mu(I_w) = \max\Big\{\mu(I_{wv}): v\in \Sigma^*\Big\} , $ hence is the most natural formula to be used to build a capacity from $\widetilde \mu$.

It is not difficult to see that with probability 1, for every $w\in \Sigma^*$, the set $\big \{v\in \Sigma^* \ \mbox{ and } p_{wv} =1\big\}$ is non-empty, so that ${\mathsf{M}}_\mu$ is well defined. Observe that by our choice , most of the coefficients $\widetilde\mu(I_w)$ equal 0, hence typically one has ${\mathsf{M}}_\mu(I_w) <\!\!\!<  \mu(I_w) $ when $\lim_{j\to+\infty}\max\{\mu(I_w):w\in \Sigma_j\}=0$.

The definition of ${\mathsf{M}}_\mu$ can be rephrased as $${\mathsf{M}}_\mu(I_w) = \max \left \{\mu(I_v): v\text{ survives, $[v]\subset[w]$}\right\} =  \max\left\{\widetilde\mu(I_{wv}): v\in \Sigma^*   \right\}.$$

We notice


the distribution and the scaling behavior (with respect to $\mu$) of the surviving vertices. Also, results on large deviations for Gibbs measures, heterogeneous mass transference principles (which combines ergodic and approximation theories) and percolation theory, are involved.

$\bullet$ One may also want to describe the asymptotical statistical distribution of ${\mathsf{M}}_\mu  $ through the notion of large deviations, as is often the case in statistical physics.

\[defsmu\] Let $\mu\in  \mathcal{C}([0,1]^d) $ with full support. For every set $I\subset {\mathbb{R}}^+$, and every integer $j\geq 1$, set $$\mathcal{E}_\mu(j,I) =
  \left\{ w\in \Sigma_j: \frac{\log_2 \mu(I_w)}{ {-j}} \in
I \right\}.$$ If $H\geq 0$ and ${{\varepsilon}}>0$, we introduce the notation $$\mathcal{E}_\mu(j,H\pm {{\varepsilon}}) =
  \left\{ w\in \Sigma_j: \frac{\log_2 \mu(I_w)}{ {-j}} \in
[H-{{\varepsilon}},H+{{\varepsilon}}] \right\}.$$ Then, the lower and upper large deviations spectra of $\mu$ are respectively$w$.

Fix ${{\varepsilon}}>0$ so small that $\eta+{{\varepsilon}}<1$ and $({{\varepsilon}}_j)_{j\geq 1}$ a positive sequence converging to zero, such that $0<{{\varepsilon}}_j\leq {{\varepsilon}}$ and $\sum_{ j\geq 1} 2^{-j {{\varepsilon}}_j} <+\infty$.

Let us introduce $ \widetilde  Z_j^1  =\sum_{u\in \Sigma_j}  r_u $, the number of $1$-reconstructible words at generation $j$. The random variable $ \widetilde Z_j^1$ is a sum of non-independent random variables with common law the Bernoulli law with parameter $\tilde p_j$. Markov’s inequality yields $\mathbb{P}(  \widetilde Z^1_j \geq  2^{j{{\varepsilon}}_j} 2^j \tilde p_j) \leq 2^{-j{{\varepsilon}}_j}$, and Borel-Cantelli’s lemma implies that almost surely, for $j$ large enough, we have $$\label{majZ1}
\widetilde Z_j^1 \leq \tilde C 2^{j{{\varepsilon}}_j} 2^j \tilde p_j \leq   C_1 2^{j (\eta+{{\varepsilon}}_j)},$$ for some other constant $  C_1$. This implies that $\Sigma^* $ is not $1$-reconstructible, since


that $H \in (H_{\min},H_s) \mapsto -\dfrac{{D_\mu}^*\big({D_\mu}'(H)\big)}{{D_\mu}'(H)}$is injective as well. Equation yields finally $\alpha = {H_\ell}({{\widetilde \eta}})$.

[The previous definitions and discussion clarify the origin of the parameters introduced to state Theorem \[thm-0\]]{}. The rest of the paper is devoted to the proof of the multifractal properties of ${{\mathsf{M}}_\mu}$ definied by .

Analysis of the surviving vertices {#surv}
==================================

Basic properties of the distribution of the surviving vertices
--------------------------------------------------------------

Recall the Definition \[def11\] in which ${\mathcal{S}_j(\eta)}$ is defined, and recall that $x_w$, defined by , is the dyadic point corresponding to the projection of the finite word $w\in \Sigma_j$ to ${[0,1]}^d$. The first question concerns the distribution of the points $x_w$, for $w\in {\mathcal{S}_j(\eta)}$.

For every $j\geq 1$, and every finite word $W\in \Sigma^*$, we define $$\mathcal{S}_j(\eta,W) = \{w\in  \mathcal{S}_j(\eta): I_w \subset I_W\}.$$

The set $ \mathcal{S}_j(\eta,W)(1-2^{-j(1-\eta)})^{2^{j- \lfloor j(\eta-{{\varepsilon}}_j)\rfloor}}\\
&\le& 2^{ \lfloor j(\eta-{{\varepsilon}}_j)\rfloor} \exp (-2\cdot 2^{j{{\varepsilon}}_j}).\end{aligned}$$ If we choose ${{\varepsilon}}_j =  (\log^2(j))/j$, we get $\sum_{j\ge 1}\mathbb{P}\Big ( \bigcup_{v\in \Sigma_{\lfloor j(\eta-{{\varepsilon}}_j)\rfloor}} \mathscr{E}(W)\Big )<\infty$. So the Borel-Cantelli lemma yields that, with probability 1, for $j$ large enough, for all $W\in \Sigma_{\lfloor j(\eta-{{\varepsilon}}_j)\rfloor}$, there exists $w\in \Sigma_j$ such that $I_w\subset I_W$ and $p_{w}=1$, i.e. $w\in\mathcal S_j(\eta,W)$.

The sequence $({{\varepsilon}}_j)_{j\geq 1}$ is now fixed.

Lemma \[lem1\] has the following consequence: Almost surely, the set of points belonging to an infinite number of balls of the form $B(x_w, 2^{-\lfloor |w|(\eta-{{\varepsilon}}_{|w|})\rfloor})$ with $p_w=1$ is exactly the whole cube ${[0,1]^d}$, i.e. $$\label{cover1}
 {[0,1]^d}= \limsup_{j\to +\infty} \ \bigcup_{w\in \mathcal{S}_j(\eta)} B(x_w, 2^{-\lfloor |w|(\eta-{{\varepsilon}}_{|w|})\rfloor}).$$

Next we obtain an upper bound for the cardinality of $\mathcal{S}_j(\eta,W)$ when $W \in \Sigma_{\lfloor \eta j \rfloor}$.

\[lem2\] With probability one, for every


the mapping $\eta'  \mapsto (\widetilde{H}_j-{{H_\ell}} )(\eta')$ is continuous, positive at $\eta'=0$, negative at $\eta'=\eta$. The continuity ensures the existence of $\eta'\in (0,\eta)$ such that $\widetilde{H}_j(\eta')={{H_\ell}}(\eta')$, and is satisfied with this $\eta'$.

- Suppose now that $\eta_\ell>0$ and recall that ${{H_\ell}}(\eta')$ ranges in $[{{H_\ell}}(\eta_\ell), H_s]$. Notice that for any $\eta'$, $j-\lfloor \eta' j\rfloor\ge j-\lfloor \eta j\rfloor$ which tends to $+\infty$ when $j\to +\infty$. Hence, by Proposition \[p1\], for $j$ large enough we have ${H_j}(\eta')\ge {H}_{\ell}({\eta_\ell})-{{\varepsilon}}^1_{j-\lfloor \eta' j\rfloor}$, so that for all $\eta'\in [\eta_\ell,\eta]$, $$\widetilde{H}_j (\eta')\ge {{H_\ell}}(\eta_\ell)-{{\varepsilon}}^1_{j-\lfloor \eta' j\rfloor}-s_j.$$ By continuity of $\eta'  \mapsto (\widetilde{H}_j-{{H_\ell}} )(\eta')$, there exists $\eta'\in [\eta_\ell,\eta]$ such that $|\widetilde{H}_j(\eta')-{{H_\ell}}(\eta')|\le {{\varepsilon}}^1_{j-\lfloor \eta' j\rfloor}+s_j$. In all cases, we found $\eta'\in [\eta_\ell,\eta]$ such that $|\widetilde{H}_j(\eta')-{{H_\ell}}(\eta')|\le{{\varepsilon}}^1_{j-\lfloor \eta' j\rfloor}+2s_j+O(1/j)$. Since $H_j$ and $\widetilde{H}_j$ differ by $o(1)$, the result follows.

$\bullet$ Finally suppose{{\varepsilon}}_p=  3\beta_p   $ and $\widehat{{\varepsilon}}_p=  {D_\mu}( \alpha^2_p) -  {D_\mu}({H_\ell}(\eta') ) >0$.

It is clear from the continuity and monotonicity of ${D_\mu}$ that $(\widetilde {{\varepsilon}}_p)_{p\geq 1} $ and $(\widehat{{\varepsilon}}_p)_{p\geq 1} $ are two positive decreasing sequences, and that $ \lim_{ p \to +\infty} \widetilde {{\varepsilon}}_p = \lim_{p\to+\infty} \widehat{{\varepsilon}}_p=0$.

For $j\ge j_p/(1-\eta')$ (hence so that $j-\lfloor \eta'j\rfloor\ge j_p$) and $W \in \Sigma_{\lfloor \eta'  j\rfloor}$, consider the event $$\mathscr{A}(\eta', \widetilde {{\varepsilon}}_p , W )=\Big\{\forall\, w'\in \mathcal{E}_\mu  \big(j-\lfloor \eta'  j\rfloor,{{H_\ell}}(\eta' )\pm \widetilde {{\varepsilon}}_p \big), \   p_{Ww' }=0\Big\}.$$

One has $$\begin{aligned}
\nonumber\mathbb P \Big(\mathscr{A}(\eta',\widetilde {{\varepsilon}}_p, W) \Big)&=(1-2^{-d(1-\eta)j})^{\# \mathcal{E}_\mu \big(j-\lfloor \eta'  j\rfloor,{{H_\ell}}(\eta' ) \pm\widetilde {{\varepsilon}}_p \big)}\\
\nonumber&\le \exp\big( {-2^{-d(1-\eta)j}\# \mathcal{E}_\mu(j-\lfloor \eta'  j\rfloor,{{H_\ell}}(\eta' )\pm  \widetilde {{\varepsilon}}_p) \big)}\\
\nonumber&\le \exp\big( {-2^{-d(1-\eta)j+(j -{\lfloor}\eta' j{\rfloor})\big({D_\mu}  ({{H_\ell}}(\eta')  )+\widehat{{\varepsilon}}_p \big)}\big)}.\end{aligned}$$ Recalling


(A(\eta_{N,k}, {{\varepsilon}}^3_j(k) , W) \Big)  \leq    2^{-d j}.$$

Observe that if $0< {{\varepsilon}}<{{\varepsilon}}'$, $\mathscr{A}(\eta', {{\varepsilon}}' ,W) \subset \mathscr{A}(\eta', {{\varepsilon}},W)$. Hence, we can choose the integer $p=\max(p_0(0),...,p_0(N-1))$, and the sequences ${{\varepsilon}}^{4,N}_j := \max ({{\varepsilon}}^3_j(0),...,{{\varepsilon}}^3_j(N-1))$ and $\widetilde j_p := \max( \widetilde j_p(0), ..., \widetilde j_p(N-1) )$, so that we have the following property: for all $0\le k\le N-1$, for all $j\ge \widetilde j_{p_0}/(1-\eta)$, for all $ W \in \Sigma_{\lfloor \eta_{N,k} j\rfloor}$, holds true with ${{\varepsilon}}^{4,N}_j $ instead of ${{\varepsilon}}^{3}_j(k) $.

Thus, $$\begin{aligned}
& \mathbb P\Big(\left\{\exists\, j\ge \widetilde  j_{p_0}/(1-\eta), \ \exists \, k\in \{0,..., N-1\},\ \exists \, W \in \Sigma_{\lfloor \eta_{N,k} j\rfloor}:  A(\eta_{N,k},{{\varepsilon}}^{4,N}_j ,W) \text{ holds} \right\}\Big )\\
&\leq   \sum_{k=0}^{N-1}   \mathbb P\Big(\left\{\exists\, j\ge \widetilde j_{p_0}/(1-\eta) \mbox{ and } \exists \,W \in \Sigma_{\lfloor \eta_{N,k} j\rfloor}: \eta' j\rfloor}$, $ \mathcal{S}_j(\eta,W)  \cap {{\mathcal{T}_{\mu,\ell}}}(j,\eta', {{\varepsilon}}^3_j) $ is not empty when $j$ becomes large. The last proposition of this section shows that its cardinality cannot be very large. This fact will be interpreted geometrically as a [*weak redundancy*]{} property from the viewpoint of ubiquity theory [@BSubiquity2; @BSubiquity3] and has nice geometric consequences for our study.

\[p4\]

1.  For all $\eta' \in [{\eta_\ell},\eta]\setminus \{0\}$, for all ${{\varepsilon}}\in(0,1)$, there exists $\beta>0$ such that with probability 1, for every $j$ large enough and all $W\in\Sigma_{\lfloor \eta'j \rfloor}$, $$\label{eq4s}
    1  \, \leq \,   \# \big (\,  \mathcal{S}_j(\eta,W)  \cap {{\mathcal{T}_{\mu,\ell}}}(j,\eta',  \beta)  \,\big)  \, \leq \,  2^{\eta'j  {{\varepsilon}}}.$$

2.  The same holds true for $\eta'   \in [{\eta_r},\eta]\setminus \{0\}$


that:

-   $|{H_\ell}( \eta_{j'_n} ) - {H_\ell}( \eta')|< {H_\ell}( \eta_{j_n} )  {{\varepsilon}}/96$,

-   $|{H_\ell}( \eta_{j_n}(N))-{H_\ell}( \eta_{j_n})|<{H_\ell}( \eta_{j_n} )  {{\varepsilon}}/96$,

-   ${{\varepsilon}}^{4,N}_{  {j'_n} }  <  {H_\ell}( \eta_{j_n} )  {{\varepsilon}}/96$.

This is possible since $\eta_{j'_n} \to \eta' >0$, ${H_\ell}(\eta')>0$, and ${H_\ell}$ is differentiable as function of $\eta'\in (\eta_\ell, \eta)$. With these choices, one sees that $$\begin{aligned}
 \frac{j_n-\lfloor j_n \eta_{j_n} \rfloor}{1+{{\varepsilon}}/12}  \big({H_\ell}( \eta_{j_n}(N))+{{\varepsilon}}^{4,N}_{  {j'_n} }  \big)  & \leq & (j_n-\lfloor j_n \eta_{j_n} \rfloor   ){H_\ell}( \eta_{j_n} )  (1-{{\varepsilon}}/48).
 \end{aligned}$$

Finally, we use to get, for $n$ large enough $$\begin{aligned}
\mu(I_{ w'_n}) & \ge  &
 C^{-1} \mu(I_{ {w_n}_{|\lfloor  j_n \eta_{j_n} \rfloor}}) 2^{-(j_n-\lfloor j_n \eta_{j_n} \rfloor   ){H_\ell}( \eta_{j_n} )  (1-{{\varepsilon}}/48)}\\
 & \ge [{{H_\ell}}(\widetilde\eta)+{{{\widetilde H}}_\ell}(\widetilde\eta),{H_s}+{{{\widetilde H}}_\ell}(\widetilde\eta))$, the triplet $$\label{triplet1}
      \big(\alpha_H:=H-{{{\widetilde H}}_\ell}({{\widetilde \eta}}), {{\widetilde \eta}},1\big)$$ belongs to the domain $\mathcal{P}_{H,0}$, and $$\label{DH01}
    D(H) \geq \frac{{D_\mu}(\alpha_H)}{1} = {D_\mu}\big(H- {{{\widetilde H}}_\ell}(\widetilde\eta)\big) .$$

2.  If $H\in [ {{H_\ell}}(\widetilde\eta)    , {{H_\ell}}(\widetilde\eta)+{{{\widetilde H}}_\ell}(\widetilde\eta))$, the triplet $$\label{triplet2}
      \left({{H_\ell}}(\widetilde\eta), {{\widetilde \eta}},\ \frac{{H_\ell}(\widetilde\eta)+{{{\widetilde H}}_\ell}(\widetilde \eta)}{H_\ell (\widetilde \eta)}\right)$$ belongs to the domain $\mathcal{P}_{H,0}$ and $$\label{DH02}
        D(H) \geq  H\frac{{D_\mu}({{H_\ell}}(\widetilde\eta) )}{{{H_\ell}}(\widetilde\eta)+{{{\widetilde H}}_\ell}(\widetilde \eta)}=H\cdot \dfrac{{{\widetilde \eta}}\cdot {D_\mu}( {{H_\ell}}(\widetilde\eta)) }{{{H_\ell}}(\widetilde\eta)} .$$

3.  If $H\in ({{H_\ell}}({\eta_\ell}),   {{H_\ell}}(\widetilde\eta)   )$, let $\eta_H\in (\eta_\ell,\widetilde\eta)$ be the unique real number such that $$\label{defetaH}
    H={{H_\ell}}(\eta_H).$$ The triplet $$\label{triplet3}
    ({H_\ell}(\eta_H), \eta_H, 1/\eta_H)$$ belongs to $\mathcal{P}_{H,0}$ and $$\label{DH03}