the hell are you doing here?" "I came to pick up some supplements for Bobby to keep him sober." "But that's not a good idea." " Shit." " What are we gonna do?" " Is that Bobby?" " No, hold on." " Angie, stay here." " No." "Angie, you can't." "Stay right here." " It's him." " What?" "No, no, don't pick it up." "Don't pick it up." "It's just gonna set him off." "Okay." "Wait." "Wait, anything you wanna do to me later, I totally absolve you." " What are you guys doing here?" " Why is she here?" "I got the supplements, so we can go now." " Hey, what's the hell going on?" " I've been here with William." "Look, Bobby, she needs to beoverall seroprevalence of HCV among donors was 7.5% (95% CI 6.8%--8.3%) and increased significantly over the study period from 7.2% (95% CI 5.8%--8.7%) in 2004 to 8.9% (95% CI 7.5%--10.6%) in 2007 (p = 0.02) (Table [3](#T3){ref-type="table"}). Similar results were seen when restricting the analysis to males, with a slightly more significant linear trend (p = 0.01).

######

Annual seroprevalence rates and linear trend analysis of HCV infection in blood donors of interior Sindh

                               **2004**    **2005**   **2006**    **2007**    **Overall prevalence**   **Chi Square test for trend p**


  Illiterate % (n)             8.6(71)     6.9(61)    10.1(67)    9.8(87)     8.8(286)                 0.16
  95% CI                       6.8--10.8   5.4--8.8   7.9--12.7   7.9--12.0   7.8--9.8                     4.8--8.7    3.0--5.7   5.7--10.3   7.1--11.9   5.8--7.7                 0.01

\* Total no. of infected blood donors

Increases in HCV seroprevalence were seen in both age groups, although not quite reaching statistical significance for either group. Significant increases in seroprevalence were also seen in literate (p = 0.03), non-first time donors (p = 0.01) and Sindhi speaking (p = 0.01) donors.

Discussion
==========

Our study finds a steady increase in prevalence in HCV infection in blood donors from interior Sindh between 2004 and 2007. This increasing trend of HCV infection is apparent in almost in


have donated blood earlier in some other facilities and remained ignorant of their HCV status and thus continued their practice of donation of blood. We did not find a similar increase in HBV infection in the blood donor population from Interior Sindh. On the contrary we found an apparent lowering trend of the infection, particularly in literate blood donors. This may be because being educated they are more health conscious. The recent introduction of HBV immunization is unlikely to be a major cause of reduction of HBV infection in the blood donor population because of the high median age of the study population.

A similar trend analysis study conducted in the Karachi blood donor population from 1998--2002 reported a statistically significant downward trend of HBV infection \[[@B15]\]. It iscomfort in 93% of patients who reported moderate to severe discomfort with standard compression technology2 Curved, unique design mirrors the shape of a woman’s breast to reduce pinching and apply uniform compression over the entire...

Based on Mindray's new generation ultrasound platform, mQuadro, M9 has raised the industry standards to an all new level. Advanced signal transmission and reception processors provide highly sensitive and accurate echo detection. Innovative transducer...


Neighbors:Did you know that the Eastside Rail Corridor (ERC) runs more than 25 miles through King County? The former railway turned multi-purpose corridor connects the cities of Renton, Bellevue, Kirkland, Woodinville, and Redmond. To raise awareness about the corridor and celebrate its multi-purpose vision (trail, high capacity transit, and utility uses), we are beginning a naming and branding effort. Don’t worry, the Cross Kirkland Corridor and Redmond Central Connector names won’t change- we’re only considering renaming the Eastside Rail Corridor as a whole. We want to hear from you! Please take a few moments to share your insights on the ERC.

Leave a Reply.

Next MeetingThe next meeting of the CHNA will be held:

Tuesday March 12, 2019 7:00 pm*Please note that the default day for meetings is the second Tuesdayby an administrator who has been given discretion to make such a law-oriented decision should not apply a fortiori to the same administrator's discretionary factual decisions.
As already indicated, Bruch, 489 U.S. at 111, 109 S.Ct. at 954 followed other ERISA cases in instructing courts to follow trust law principles in filling in ERISA's gapshere, a failure to provide a standard of review. Bruch, id. quoted Nichols v. Eaton, 91 U.S. 716, 724-25, 23 L.Ed. 254 (1875) for the long held viewdrawn from trust lawthat federal courts should not intrude on the discretion that a trust vests in its administrator:
When trustees are in existence, and capable of acting, a court of equity will not interfere to control them in the exercise of a discretion vested in them by the


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January 8th

January 11th

Iron Solari Leona (487 RP)

Sultan Tryndamere (487 RP)

Red Card Twisted Fate (375 RP)

Ravager Nocturne (260 RP)

Sale Related News

January sales have also been announced! Check out this link get a sneak peek of what's coming up in January. Thehave also been announced! Check out this link get a sneak peek of what's coming up in

A new sale starts tomorrow ! Betweenand, you'll can snagfor 487 RP,for 487 RP,for 375 RP,for 260 RP,for 487 RP,for 440 RP,for 440 RP andfor 292 RP.Continue reading for a better look at this sale's discounted skins!In case you missed it, Riot recently announced changes to discounts and sales - this includes adding a fourth champion and skin to the weekly sales!sperm preparation to IUI on the outcome ([@B4]), a variable that probably prevents the deleterious effect of oxidative stress. Adding pentoxifylline, as an inhibitor of cAMP phosphodiesterase enzyme, in semen preparation for IUI improves sperm motility in asthenozoospermic samples due to its capacity to favor increasing intracellular cAMP concentration. Applying this inhibitor has been demonstrated to exert higher and significantly different pregnancy rates in couples classified infertile for male factor ([@B5]).

Asthenozoospermia is probably the main feature in male infertility and has multifactorial origins ([@B6]). Although the prevalence of hypotiroidism is higher in females than in males, we wonder about the role of thyronines in sperm motility, considering that they act on nearly every cell in the body increasing the basal metabolic rate. In an experimental design hypothyroid rats


60% of the cases, from a mathematical point of view. Focusing on a program of assisted reproduction, at least 5 million progressive motile sperms are needed for IUI outcome. From a clinical point of view, all of the studied samples overcame this barrier by employing T4. Interestingly, overcoming the cut-off value is the only negative result obtained by comparing swim-up outcome treated with or without the hormone, suggesting that there is an upper motility limit, above which adding the hormone has no effect. Despite the proposed method is reasonable for subfertil sperms, it could not be applicable for severely impaired semen samples, as an alternative beyond ICSI. This is in accordance with findings obtained from the target group which has been benefited by this treatment.

Thyroid hormones can exertis less expensive, less invasive, and comparably effective for selected patients, as a first-line treatment for couples ([@B24]). We are currently suggesting a new physiological tool to improve this technique which requires further evaluation to validate its potentially effective application in reproduction. The discussion opens our minds to think in unknown pathways involved in sperm capacitation and gives innovative arguments to better understand infertility mechanisms.

Conclusion
==========

Our report is the first, to our knowledge to envisage a non-genomic action of thyroxine on sperm with direct impact on clinical.

This research was supported by a Clinical Grant from University of Buenos Aires Science and Technology ( UBACYT-CB06 and UBACYT 009ba ). We wish to thank Dr. Norma Pugliese and Julia Furlan for their technical support and Dr. Patricia Chenlo for statistical analysis.


Q:

C++ Pass bytes from char* to a BYTE*

I would like to know how to pass/COPY a sequence of bytes represented as a char* to a BYTE* in C++ in Windows.
Let's say I have this char* :
const char *ByteString = "\x3B\xC8\x74\x1B"

How would I COPY each byte from this char* to a BYTE *Bytes and vice-versa ?
EDIT: Thanks alot for everyone's help !

A:

The definition of BYTE is:
typedef unsigned char       BYTE;
which is not the same as a const char, so you'd need to convert it, but note that casting away const from something declared const to start with results in undefined behaviour and trying to actually change the data poses an even bigger risk.
BYTE* Bytes = reinterpret_cast<BYTE*>(const_cast<char*>(ByteString));
Edit: I just noticed that convertingIntroduction {#Sec1}
============

Patients with glioblastoma, the most malignant form of glioma, usually succumb within a few years after the diagnosis despite aggressive chemo and radiotherapies following surgery^[@CR1]^. Such disheartening therapeutic outcomes desperately call for more effective measures. However, untoward biological characteristics of glioma such as aggressive local invasion and resistance to anticancer therapy, present a daunting obstacle in achieving this goal.

Dysregulation of autophagy has been implicated in cancer cell proliferation, invasion, high histological grades, and poor prognosis in a wide spectrum of cancers. These findings highlight the possibility that autophagy-related molecules may prove useful as prognostic markers and/or therapeutic targets. In addition, many of anticancer drugs along with ionizing radiation (IR) are known to activate autophagy in cancer cells. The functional significance of autophagy activation associated with cancer therapeutics


that zinc may have a direct effect on the degradative function of lysosomes, and consequently on cell survival. To test this hypothesis, we examined the effects of depleting or adding labile zinc on these events. In TPEN-treated (zinc-depleted) cells, changes similar to those seen in *MT3*-downregulated cells were observed. First, the levels of both LC3-II and p62 markedly increased after irradiation (Fig. [5a,b](#Fig5){ref-type="fig"}, see Supplementary Fig. [4(a,b)](#MOESM1){ref-type="media"} original blot). Second, striking accumulation of dilated RFP-LC3 (+) AVs in lysosomes was observed (Fig. [5c](#Fig5){ref-type="fig"}). These findings indicate that lysosomal degradation of AVs was reduced, and hence autophagy flux was arrested as in the case of *MT3*-knockdown cells. The clonogenic survival of TPEN-treated cells were also reduced after irradiation (Fig. [5d](#Fig5){ref-type="fig"}). In contrast to TPEN treatment, addition of zinc chloride (Zn) in the media,Anti-microtubule-associated protein light chain 3 (LC3) and anti-p62 antibodies were obtained from Novus (Littleton, CO, USA) and MBL (Nagoya, Japan), respectively. Anti-β-actin and anti-beclin1 antibodies were from Cell Signaling (Beverly, MA, USA).

Plate colony forming assay {#Sec14}
--------------------------

Cells were seeded in six-well plates at a density of 100 (for controls) or 200 cells (for irradiated cells) per well and allowed to attach overnight before irradiation. Fourteen days after irradiation, cells were fixed with 4% paraformaldehyde and stained with Giemsa staining reagent (Sigma). The number of colonies with \> 50 cells was counted under a dissecting microscope. The cell survival fraction or relative survival rate was expressed in terms of the plating efficiency in control groups: the number of colonies formed after treatment divided by both the number of cells seeded and the


General view of the Principality of Monaco, 30 June 2011. Photo by BGNES

Residents of Monaco boast the highest average life expectancy in the world, 89.73 years, or five years more than Macau, which ranks second on the list at 84.41.

According to the CIA World Factbook, as cited by CNN, the world average is 67.07 years.

The ranking includes 220 countries and territories.

There are three other European states among the top ten - San Marino (83.01), which ranks third, followed by Andorra (82.43) and Italy (81.77), which occupies 8th place.

Bulgaria ranks 114th with an average life expectancy of 73.59 years.

The top performer on the Balkans is Greece (79.92 years, 30th place).

Compared to the other Balkan states, Bulgaria manages to outpace only Turkey, which scores 72.5 years and ranks 125th.

The bottom     array_push($cart, $informatie['obiect']);
    }
    mysql_query("INSERT INTO membri_shop_iteme set iteme_arme = ".$informatie["obiect"]." where id_jucator = ".$informatie_player['id']." "); // Here is the problem.

}

Where's the problem? I tried adding implode(', ', $cart); but still i can't add them into database.
Thanks for helping.

A:

may be its string problem $informatie["obiect"] to $informatie['obiect']
  mysql_query("INSERT INTO membri_shop_iteme set iteme_arme = ".$informatie['obiect']." where id_jucator = ".$informatie_player['id']." "); // Here is the problem.

to
  $newObject=join(",",$cart);
  mysql_query("UPDATE membri_shop_iteme SET iteme_arme = '".$newObject."' where id_jucator = ".$informatie_player['id']." "); // Here is the problem.


The income tax cuts in the 2018 federal budget are likely to be modestly regressive, giving high earners a lower share of the overall tax burden. But by 2028 income tax will be higher across the board.

Though Google has reported significantly more profits in Australia, the profit margins of the local company remain very low compared to its worldwide group.
DAN HIMBRECHTS/AAPMay 24, 2018walked to the front entrance only to find signs saying,

“ Not a voter entrance, to vote please enter at the Alameda light.”

Later in the day, some placed a hastily scrawled sign in front of the visitor’s lot, redirecting motorists to the school’s gymnasium on Alameda Boulevard.

But another sign said voters couldn’t park in the lot adjacent to the gym. Most voters ignored that sign and parked regardless.

Barbara Tarazon was using a walker to stabilize herself on Tuesday afternoon. She said she would have appreciated some handicap-designated spaces closer to the polls, but otherwise didn’t have issues finding the venue. That’s a sentiment echoed by married couple Jean and Bob Gibson. He needs a cane to walk, and the distance proved challenging he said.

A spokesman with the Bernalillo County


secondary to other causes were excluded. There was no patient with alcoholic hepatitis in our study, so no difficulty was encountered in measuring serum creatinine in patients with high bilirubin levels. Diagnosis of HCV was confirmed by serological assay and liver cirrhosis was confirmed by ultrasonography. CPS was determined and lab reports were taken on the same day. RD associated with HCV-induced liver cirrhosis was detected in the patients on study inclusion by serum creatinine at the time of admission. Guidelines of the International Ascites Club's definition were used to define patients having RD on the basis of serum creatinine.[@R25] Patients were divided into two groups as having RD (serum creatinine≥1.5 mg/dL) and not having RD (serum creatinine\<1.5 mg/dL). Estimated GFR (eGFR) was calculated by CKD-EPI collaboration formula.[@R26](IQR=15 years). A total of 40 out of 70 (57%) had ascites while the rest 30 (43%) did not develop ascites. About 30/70 (43%) had HE while the rest 40 (57%) did not. Out of 70 patients, 30 (43%) patients developed RD and 40 (57%) did not develop RD. Demographic details of the patients are presented in [table 1](#T1){ref-type="table"}. The distribution of patients having HE into the four grades is presented in [table 2](#T2){ref-type="table"}.

######

Demographic details (n=70)

  Variable                   N=70
  -------------------------- -------------
  Gender\*
   Male


urea, creatinine and eGFR were significantly different among the patients with and without RD.

Our study showed a significant relationship between CPS and RD. RD was significant in patients with CP grade B and C (58%) as compared with those with grade A (0%). Siregar and Gurning[@R29] also found that no one (0%) in grade A of liver cirrhosis developed RD whereas 37.2% of patients with grade B or C developed renal failure. This shows that higher the severity of cirrhosis greater will be the risk of renal injury. To prove this, we correlated the CPS with serum creatinine and eGFR and found a significant direct correlation between serum creatinine with CPS (r=0.757, p=0.000) and an inverse correlation with eGFR (r=−0.359, p=0.002). Siregar and Gurning[@R29] also reported a positivecirrhosis.

Conclusion {#s5}
==========

Ascites and encephalopathy are associated with RD in HCV cirrhosis. Patients with CP B and C are more prone to have RD as compared with CP A. Greater the CPS greater is the extent of renal injury. A cut-off value of CPS 8.5 is highly sensitive to predict RD in HCV-related liver cirrhosis and can be used as screening test due to high sensitivity. This may help in diuretic prescription for the patients and monitoring the extent of RD.

**Contributors:** HWB planned and designed the study, and contributed in manuscript writing as well. UT contributed in data collection, entry and manuscript writing. NAC analysed the data, contributed in manuscript writing and reviewing the paper. SB contributed in data collection and quality assurance. MH contributed in data collection, technical


crown in a row, completing the race in 2:27.46.

Senior Wilena Little, the two-time Hernando Today Girls Track Athlete of the Year, has been hampered by leg injuries but added her 11th and 12th individual county titles, winning the long jump with a 15-11 and the 200 (25.80).

That's four consecutive times winning the 200, and a three-peat in the long jump for Little.

Ty'Rhonza Harris took second to pace the county in the triple jump two years straight, with a 33-1 1/2.

Also, Alexandra Ede, Harris, Joy Jackson and Blackwell paced the field in the 4x800 (10:35.56).

Like Harris, Hernando junior Lauren Plaugher repeated by coming out on top in the discus (114-6 1/2).Lollapalooza 2014, which goes down from August 1-3 in Chicago, announced its 2014 lineup. Artists include Eminem, Outkast, Kings of Leon, Arctic Monekys, Skrilex, Broken Bells and tons more. 3-day passes are sold out, but single day tickets go on sale today at 10 AM.

While last night's Wester Hall show (2/6) wasn't as (indie) star-studded as the Cupid Deluxe record release show at 285 Kent back in December, Blood Orange's Dev Hynes has more than enough charisma to hold his own. This was Dev's first big, proper show since the release of his acclaimed second Blood Orange album and, while David Longstreth didn't make an appearance, Caroline Polachek of Chailift was on hand for night opener "Chamkay" and Queens rapper Despot joined later for his verse on "Clipped


moniker, Lightspeed Champion, for a show at Cameo Gallery. It was within this context that he and girlfriend/collaborator Samantha Urbani performed a one-off Trans-Pecos show under the name Gayer on Monday night (12/30).

No one really knew what to expect from the concert. Much of the afternoon was spent checking the Facebook event, where promoter Jason Mandel answered any and all questions about what exactly was happening that night. He promised a live show with the duo "doing metal rap and other crazyness (sic)" and in the end, we were slightly surprised to find that the couple completely (and efficiently) fulfilled these expectations.

They opened with the metal portion, a chaotic, explosive track that found Dev playing an electronic (Casio?) guitar over swirls of pre-recorded drums while Samantha donned aVideo of "Rap God" is below. On his state-of-the-fundraiser Tumblr post, Dev suggested "Maybe it's time I down some anxiety medication see a doctor and try and play some shows," and this performance felt a lot like him just getting out there and having some fun.

The show concluded after "Rap God," which left a lot of people scratching their heads - wondering what exactly happened, if two songs was an acceptable length for a show, whether or not this performance was more or less interesting than what they expected, and perhaps even if they should be reconsidering their evaluation of Eminem's newest album.

As the couple packed up their gear, the house music kicked into a dance-tempo version of "Time Will Tell." The crowd reacted immediately, dancing along and


but I have. Friends of mine have been more than kind to me, friends some people may not have, families in the same position would not be as fortunate... i'm aware of this.

If I am honest, the fundraiser makes me feel extremely uncomfortable. This isn't me saying I don't need the money, to reiterate, i have lost everything. But maybe it's time I down some anxiety medication see a doctor and try and play some shows y'know? There are things i can do, although it will take years, that can help myself rebuild, a huge part of me is still struggling with understanding the events of two nights ago, and where to take my life from here.

This isn't me being unappreciative. Tears stream down my face when Samanthayou think of their list? Did your favorite song make it? Any glaring omissions?

The week of its release, he celebrated with an uber-packed, guest-filled show at 285 Kent that was also the debut of his new full live band. (Sound/feedback issues aside, they were really good at 285.) While he hasn't made any full tour plans, Dev has announced his next NYC show which happens February 6 at Webster Hall. Is that close enough to be considered a Cupid Deluxe Valentine's Day show? Tickets go on sale Friday (12/13) at noon with an AmEx presale starting Wednesday (12/11) at noon.

NPR Music posted their 50 Favorite Albums of 2013, and as usual it included a lot of classical, jazz, world music, but also many of the indie/pop/rap/metal that shows


Tengo, Waxahatchee, Autre Ne Veut, Glass Candy, and more. Pictures of the final day of the festival are in this post.

If you haven't been keeping up with our coverage of Pitchfork festival, day 1 pictures and review are HERE, and more pictures are HERE and HERE. Day 2 pictures and review are HERE and more pictures are HERE. Day 3 pictures continue below...

As mentioned, Chicago's Pitchfork Music Festival is returning to Union Park from July 19-21 with sets from Bjork, Joanna Newsom, Belle & Sebastian, R. Kelly, Solange, Rustie, Low, The Breeders, Swans, Savages, Merchandise, Julia Holter, KEN mode, White Lung, TNGHT, Evian Christ, Waxahatchee, El-P, Killer Mike, and more across three stages (Red, Blue, and Green). The set times for the festival have now been announced, andyou can check out the full day-by-day schedule below.

While Phoenix prepare for a much bigger tour that will include a stop at Brooklyn's Barclays Center in October (tickets), the French band wrapped up their post-Coachellatour of smaller North American venues at Harlem's historic Apollo Theatre last night (5/13). The band played a slightly longer set than their Sirius-sponsored show at Music Hall of Williamsburg last month, adding "Too Young" from their first album and "Fences" from Wolfgang Amadeus Phoenix to the mix. And like at MHOW, frontman Thomas Mars got into the crowd to sing as well.

Opening was Blood Orange, an increasingly rare sight from Dev Hynes who is spending more and more time in the producer's chair these days. Photos from the Apollo are in this post.

In


other news, Phoenix's next single from Bankrupt! is "Trying to Be Cool" and the band have released the individual "stems" from the track so that anyone can have a go at remixing it. You can download them here and check out a Silver Swans remix below.

Blood Orange (aka Dev Hynes) has a few dates scheduled for this year, including a few in NYC. The first is a benefit for LGBT rights organization Human Rights Campaign at Le Poisson Rouge on May 4 with Creep, MEN (the JD Samson one), Light Asylum, Nina Sky, and "surprise special guests." It's being hosted by Amanda Leigh Dunn and Becka Diamond is DJing. Tickets for that benefit are on sale now.

A few days later, both Dev and Creep will be headed to// Sample event data
module.exports ={
  "session": {
    "new": true,
    "sessionId": "amzn1.echo-api.session.[unique-value-here]",
    "attributes": {},
    "user": {
      "userId": "amzn1.ask.account.[unique-value-here]"
    },
    "application": {
      "applicationId": "amzn1.ask.skill.[unique-value-here]"
    }
  },
  "request": {
    "locale": "en-US",
    "timestamp": "2016-10-27T18:21:44Z",
    "type": "IntentRequest",
    "requestId": "amzn1.echo-api.request.[unique-value-here]",
    "dialogState": "BEGINNING",
    "intent": {
      "slots": {
        "toCity": {
          "name": "toCity",
          "confirmationStatus": "NONE"


       },
        "travelMode": {
          "name": "travelMode",
          "confirmationStatus": "NONE"
        }
      },
      "name": "PlanMyTrip"
    }
  },
  "version": "1.0",
  "sessionAttributes": {},
};
comment. Challenge facts, but don't simply ignore them.4. Use a name. If it's important enough to say, it's important enough to put a name to.5. Above all: Act with honour. Say what you mean, and mean what you say.


Aspen Hill MD Real Estate & Homes for Sale

0 Properties Found

The median home value in Aspen Hill, MD is $316,200.
This is
lower than
the county median home value of $402,000.
The national median home value is $177,414.
The average price of homes sold in Aspen Hill, MD is $316,200.
Approximately 61.03% of Aspen Hill homes are owned,
compared to 34.75% rented, while
4.23% are vacant.
Aspen Hill real estate listings include condos, townhomes, and single family homes for sale.
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Please click the Refine Your Search button below to find other properties in the area.said Rafferty, who is African-American and whose husband is white. "They think, 'If it doesn't make sense to me it must not be right."

After McCain's report, Rafferty posted to Twitter a selfie of her with her two children, ages 5 and 5 months.

"I know they don't look like me, but I assure you, I grew them in my belly," Rafferty wrote to McCain.

Earlier this month, McCain claimed on Phoenix radio station KTAR that the woman was waiting for a man who bought the child to get off a plane and that her Jan. 30 report to police had stopped the trafficking. She urged people to speak up if they see anything odd.

"I came in from a trip I'd been on," McCain said. "I spotted — it looked odd


News, views and top stories in your inbox. Don't miss our must-read newsletter Sign up Thank you for subscribing We have more newsletters Show me See our privacy notice Invalid Email

The world's largest flying insect has been discovered in China - and it's bigger than a human hand.

The huge aquatic bug has a wingspan of 8.27 inches and has pincers as well as long teeth.

After being discovered in Sichuan Province , it was examined by experts at the Insect Museum of West China where it was found to be an unusually big specimen of the giant dobsonfly.

It measured 21cm, breaking the previous record held by the South American helicopter damselfly which had a wingspan of 19.1cm.

(Image: Caters)

Giant dobsonflies are normally found elsewhere across China, India and Vietnam butand efficient. Find a simple example here or checkout my answer on this thread https://stackoverflow.com/a/37560755/5460053

It is not working for two fields because of the following lines in getQuotes() method of DBAccess class :
    cursor.moveToFirst();
    while (!cursor.isAfterLast()) {
        list.add(cursor.getString(0));//Adding org_name first. org_name is added at indexes : 0,2,4,...
        list.add(cursor.getString(cursor.getColumnIndex("contact_no")));//Then adding contact_no. contact_no is added at indexes : 1,3,5,...
        cursor.moveToNext();

    }

Then while creating a datasource for the adapter, org_name and contact_no are added at alternate indexes
    List<Organization> rowItem=new ArrayList<Organization>();
    for(String quote:quotes){
        Organization temp=new Organization(quote);//I wonder how this


Aortic aneurysms are enlargements of the aorta that pose a health threat due to potential rupture. Minimally-invasive repair by endovascular stent grafts (endografts) has become a viable treatment option that avoids the risk of traditional open surgical repair. However, these endografts can only be used when the graft can be placed in a stable position without covering major branch vessels. This typically excludes patients with abdominal aortic aneurysms adjacent to the renal arteries (juxtarenal aneurysms) from endovascular treatment. To allow for endovascular repair of a wider range of aneurysm cases, surgeons will sometimes cut holes in the stent grafts to accommodate specific branch vessel origins, a process known as 'fenestration'. The openings are located based on CT images of the vessel origins. Longitudinal distances are measured, and relativethe last Brad saw his sister alive.
Mr. Clayton was employed by the Lee County Extension Service. He was out in the field all day, and did not get off work until 6:00 or 6:30 that evening. He went to the softball game, arriving there around 9:00. Following the game he and Brad returned to the Clayton residence, arriving around 11:30.
Amy was not home, and around midnight Mr. Clayton became worried. He telephoned Mrs. Clayton who came home. He called some of Amy's friends. Around 1:00 a.m. he notified the police, who came to the Clayton residence, and Mr. Clayton accompanied them looking for Amy. They traced the area where she normally jogged. The Claytons spent a sleepless night, continuing to search and wait for Amy. Around 6:00 a.m.


It was delivered by Monts to a Lee County deputy at the county line shortly after 1:00 p.m. This picture, however, is not in the record.
Monts' version of what transpired that afternoon was given at a pre-trial suppression hearing. Later that afternoon, according to Monts, he ran into Bevill at a barn in the north part of Pontotoc County. After about another hour, according to Monts, he received a radio call asking him "if I knew where I could pick this subject up at." Monts then attempted, without initial success, to locate Bevill. Still later, according to Monts, he received another radio call, and this time recognized Rickels' voice on the radio. The Lee County sheriff's office radioed "to see if I had went [sic] 10-15 with thea search warrant of Bevill to obtain from him a sample of blood, saliva and hair from all parts of his body. A search warrant was issued by Thomas J. Gardner, III, circuit judge, authorizing this search. Because the personnel at the Mississippi Crime Laboratory requested additional samples, Rickels again on August 18 signed another affidavit for a search warrant, and Judge Gardner issued a search *704 warrant on that date for samples of the blood, saliva and hair of Bevill.
On August 21 a hearing was held before Judge Gardner to revoke Bevill's probation. Rickels testified at this hearing that when he questioned Bevill he was not under arrest, and was only questioned as a possible witness because he had been in the area where the crime was


truck.
Bevill did not testify.
Other witnesses testified for both the State and the defense, but the above recitation covers the salient facts on the issue of his guilt.
Following instructions by the court, the jury first returned a verdict of guilty of capital murder, and following a sentencing hearing, the jury unanimously found that Bevill should suffer the death penalty.

LAW

I. SUFFICIENCY OF EVIDENCE
Bevill argues that evidence against him was "too flawed" to support a conviction of capital murder.
*707 He first attacks the hair analysis, not as to the sufficiency, however, but the witness Andrews giving statistical probability based upon a Canadian study. Hair analysis is a very useful took in criminology. The circuit judge upon retrial should be guarded in the use of statistics in buttressing an expert witness's testimony,although probability analyses may be admissible in appropriate and carefully circumscribed instances. See: United States v. Massey, 594 F.2d 676, 36 A.L.R.3d 1194 (8th Cir.1979); State v. Carlson, 267 N.W.2d 170 (Minn. 1978); People v. Di Giacomo, 71 Ill. App.3d 56, 27 Ill.Dec. 232, 388 N.E.2d 1281 (1979); State v. Clayton, 646 P.2d 723 (Utah 1982); Pitts v. State, 273 Ark. 220, 617 S.W.2d 849 (1981); 1 D. Louisell & C. Mueller, Federal Evidence, § 104 (1977); Guadette & Keeping, An Attempt at Determining Probabilities in Human Scalp Hair Comparison, 19 Forensic Science 599 (1974); Hair Analysis, 38 Proof of Facts 2d 377 (1984).
The proof of the blood type in both the victim and Bevill being type "O," and that this was the type found in all the


381 So.2d 983, 994 (Miss. 1980). An accused who does not intend to testify himself under oath cannot be permitted, any more than any other litigant, to have the jury consider as evidence any statements of fact *711 not subject to rigorous cross-examination of the witness under oath.

V. ADMISSIBILITY OF BLOOD AND HAIR SAMPLES
Schmerber v. California, 384 U.S. 757, 86 S.Ct. 1826, 16 L.Ed.2d 908 (1966), holds that the involuntary taking blood from a person under arrest for driving while intoxicated does not implicate the Fifth Amendment privilege against self incrimination. Also, Wesley v. State, 521 So.2d 1283, 1286 (Miss. 1988); Williams v. State, 434 So.2d 1340, 1345 (Miss. 1983). As to the Fourth Amendment, the Court held: "The overriding function of the Fourth Amendment is to protect1303 (Miss. 1984), that "[p]robable cause [for the issuance of a search warrant] exists when facts and circumstances within an officer's knowledge, or of which he has reasonable trustworthy information, are sufficient within themselves to justify a man of average caution in the belief that a crime has been committed and that a particular person committed it." 455 So.2d at 1304. See also, Holland v. State, 263 So.2d 566 (Miss. 1972) Probable cause, however, means less than evidence which would justify condemnation. See, Hester v. State, 463 So.2d 1087 (Miss. 1985); Powe v. State, 235 So.2d 920 (Miss. 1970).
The United States Supreme Court in Illinois v. Gates, 462 U.S. 213, 103 S.Ct. 2317, 76 L.Ed.2d 527 (1983), set a "totality of the circumstances" approach and stated, in determining


might have to be such a favorable state witness. Any evidence of the prosecution's participation in the expungement of public record of a criminal conviction of Renfroe would, of course, be relevant as bearing on Renfroe's impartiality, or direct interest in testifying for the State. Upon remand, the defense should be afforded the opportunity to ascertain whether or not the prosecution participated in any way in the expungement of some conviction of Renfroe, and if so, to cross-examine Renfroe of such facts as a basis for showing special motive or interest in testifying for the State. Rules 401, 402, 404(b) MRE. The full factual development of the prosecution's involvement, if any, can be developed at a pre-trial hearing or in chambers, and if it should develop that thethem, or not. In any event, Bevill was fully informed as to Clark's testimony, and the letters were repetitive and non-exculpatory.
We do take this occasion to remind circuit judges and district attorneys that it is of the utmost importance that Rule 4.06 be liberally applied so as to give the accused an opportunity to view for himself whether or not material is exculpatory. As we stated in Williamson v. State, 512 So.2d 868, 882 (Miss. 1987)
More recently, we have held that prosecuting attorneys should make available to attorneys for the defense all materials, whether written or recorded, in order that the defense may determine whether or not the material is useful to the defense of the case. Hentz v. State, 489 So.2d 1386, 1388 (Miss. 1986). The statements


in this case clearly fall into this category and should be made available to the defense prior to the retrial of this case. Further, we take this opportunity to remind circuit judges and prosecutors alike. Rule 4.06 envisions a two way discovery and contemplates complete co-operation between the parties in order to avoid trial by ambush and to ensure that the criminal defendant is afforded a fair trial. Although our decisions in this area have been something less than consistent, we urge trial judges especially to pay close attention to the guidelines set forth in Rule 4.06 and our caselaw interpreting it in order to avoid costly errors which might otherwise cause reversal. See, Hentz v. State, 489 So.2d 1386, 1389 (Miss. 1986); see also, White v. State,giving AJ Allmendinger a second chance after firing
the driver last summer for failing a random NASCAR drug test. Allmendinger
is making his IndyCar debut Sunday at Barber Motorsports Park. Then AJ will
race in Long Beach without a sponsor to give him more seat time before the
Indianapolis 500.


Thursday, February 26, 2015

The Aurora Fox Theatre Company announces 31st Season (2015 – 2016)

Conceived for the Stage by STEVE CUDEN and FRANK WILDHORNBook and Lyrics by LESLIE BRICUSSEMusic by FRANK WILDHORN

Based
on the classic story by Robert Louis Stevenson and featuring a
thrilling score of pop rock hits from multi-Grammy and TONY nominated
Frank Wildhorn & double Oscar and Grammy-winning Leslie Bricusse, Jekyll and Hyde
is about the epic struggle between good and evil. A devoted man of
science, Dr. Henry Jekyll is driven to find a chemical breakthrough that
can solve some of mankind's most challenging medical dilemmas. Rebuffed
by the powers that be, he decides to make himself the subject of his
own experi-mental treatments, accidentally unleashing his inner demons
along with the man the world would come to know as Mr. Hyde.

November 27 –         }
        },
        "splitter": {
            "name": "Identity",
        },
        "aggregators": {
            "names": ["PWA"]
        },
    }
)

models.add(
    "imagenet_res50",
    {
        "name": "resnet50",
        "resnet50": {
            "load_checkpoint": "torchvision://resnet50"


}
    }
)
extracts.add(
    "imagenet_res50",
    {
        "extractor": {
            "name": "ResSeries",
            "ResSeries": {
                "extract_features": ["pool5"],
            }
        },
        "splitter": {
            "name": "Identity",
        },
        "aggregators": {
           "names": ["PWA"]
        },
    }
)

models.add(
    "places365_res50",
    {
        "name": "resnet50",
        "resnet50": {
            "load_checkpoint": "/data/places365_model/res50_places365.pt"
        }
    }
)
extracts.add(
    "places365_res50",
    {
        "extractor": {
            "name": "ResSeries",
            "ResSeries": {


"aggregators": {
            "names": ["PWA"]
        },
    }
)

cfg = get_defaults_cfg()

models.check_valid(cfg["model"])
extracts.check_valid(cfg["extract"])
research has been done to enhance the therapeutic efficacy of β-Sit using drug delivery systems. Most studies conducted with β-Sit have focused on using it and its derivatives as an excipient to stabilize drug release or to enhance drug absorption \[[@B11-pharmaceutics-10-00232],[@B12-pharmaceutics-10-00232],[@B13-pharmaceutics-10-00232],[@B14-pharmaceutics-10-00232],[@B15-pharmaceutics-10-00232]\]. However, in an earlier study, liposomal formulation containing β-Sit increased the natural killer cell activity and decreased colonies of metastatic B16BL6 melanoma cells in lungs of treated mice \[[@B16-pharmaceutics-10-00232]\]. In other studies, cyclodextrins (CD) have been used to enhance the aqueous solubility and bioavailability of β-Sit. For example, several biological evaluations of β-Sit conducted by Awad et al. against a panel of cancer cells involved using 2-hydroxypropyl-β-cyclodextrin (HP-βCD) as a carrier vehicle \[[@B1-pharmaceutics-10-00232],[@B3-pharmaceutics-10-00232],[@B4-pharmaceutics-10-00232],[@B17-pharmaceutics-10-00232]\]. These studies demonstrated that β-Sit inhibited cell proliferation at 16-32 μM concentration levels after


dichloromethane (DCM). Working standard solutions were prepared by further dilution of the β-Sit stock in DCM. The absorbance of β-Sit in the standard solutions was measured at 622 nm, 10 min after adding Liebermann-Burchard reagent using a microplate reader with a quartz 96-well plate (FLUOstar Omega, BMG labtech, Ortenberg, Germany). A calibration curve was obtained by plotting absorbance versus the concentration of β-Sit standard solutions in DCM. The quantity of β-Sit, encapsulated or released from the nanoparticles, was determined according to the calibration curve prepared from standard solutions of β-Sit, but in this case after extraction of β-Sit with a known volume of dichloromethane (DCM). All experiments were carried out in triplicate. In each case, the presence of interfering substances in the samples that could affect the UV--visspectrum of β-Sit was accounted for with the appropriate blank samples. All blank media had negligible absorption at 622 nm.

2.3. Preparation of Nanoparticles {#sec2dot3-pharmaceutics-10-00232}
---------------------------------

β-Sitosterol-loaded PLGA (β-Sit-PLGA) and β-sitosterol-loaded-PEG-PLA (β-Sit-PEG-PLA), as well as blank PLGA and PEG-PLA nanoparticles, were prepared by a simple emulsion-diffusion-solvent evaporation method \[[@B31-pharmaceutics-10-00232]\]. The organic phase was prepared by dissolving PLGA and β-Sit in a volatile organic solvent. Then, the organic solution containing polymer and β-Sit was emulsified with a 2% solution of PVA in a ratio of 5:1 *v*/*v* (aqueous phase to organic phase) while vortex-mixing on high. The oil-in-water emulsion formed was further sonicated using a probe sonicator for 2 min to facilitate nanoparticle formation. The emulsion was stirred for 15 h using a magnetic stirrer to evaporate the organic solvent and to


= \frac{Actual~weight~of~\beta - Sit~\left( {mg} \right)~in~nanoparticle~suspension}{Theoretical~weight~of\beta - Sit~ + Theoretical~weight~of~polymer} \times 100$$

2.4. In Vitro Release Profile {#sec2dot4-pharmaceutics-10-00232}
-----------------------------

In vitro release of β-Sit from β-Sit-PLGA and β-Sit-PEG-PLA nanoparticles was determined in PBS (PBS, 0.01 M, pH 7.4) and PBS with 0.2% Tween 20. Given the very low aqueous solubility of β-sitosterol, Tween 20 was included in the release medium to maintain sink conditions \[[@B33-pharmaceutics-10-00232]\]. For each sample, 1.5 mL of the nanoparticle suspension corresponding to approximately 0.09 mg/mL of β-Sit was measured and centrifuged. The pellet was then re-suspended in 1.5 mL of PBS or PBS with 0.2% Tween 20. These samples were incubated at 37 ± 0.5 °C in a shaker (Mixer HC, Starlab international GmbH, Hamburg, Germany) mixing at 300 rpm. At preselected time intervals, the medium wasformulations, as described below.

### 2.6.1. Cell Culture {#sec2dot6dot1-pharmaceutics-10-00232}

MCF-7 cells were cultured in EMEM, supplemented with 10% FBS, 1% penicillin/streptomycin, 2 mM L-glutamine, and 1% non-essential amino acids in a humified environment at 37 °C and 5% CO~2~. On the other hand, MDA-MB-231 cells were grown in Dulbecco-modified eagle's medium (DMEM) supplemented with 10% FBS and 1 % penicillin/streptomycin in a humidified incubator at 37 °C and 5% CO~2~.

### 2.6.2. Cellular Uptake by Flow Cytometry {#sec2dot6dot2-pharmaceutics-10-00232}

Considering that β-Sit is a non-fluorescent molecule, coumarin-6 was incorporated as a fluorescent dye during nanoparticle formulation to study the cellular uptake of β-Sit-PLGA and β-Sit-PEG-PLA. Aliquots of MDA-MB-231 or MCF-7 cells (5 × 10^4^ cells) were seeded in 24-well plates in triplicate and incubated at 37 °C for 24 h. The cells were


then transfected with 100 μL of courmarin-6-labeled β-Sit-PLGA (β-Sit-PLGA-C6) and coumarin-6 labeled β-Sit-PEG-PLA (β-Sit-PEG-PLA-C6) nanoparticles. After predetermined time periods, the cell medium was discarded, and cells were trypsinized and washed with cold PBS twice. The cells were then examined with a flow cytometer (Attune NxT flow cytometer, Thermofisher Scientific, Waltham, MA, USA) at an excitation wavelength of 488 nm and detection fluorescence of 525 nm. Data were collected for 10,000 gated events per sample \[[@B36-pharmaceutics-10-00232]\].

### 2.6.3. Confocal Microscopy {#sec2dot6dot3-pharmaceutics-10-00232}

MCF-7 and MDA-MB-231 cells were seeded at a density of 2 × 10^4^ cells per well in 8-well chamber slides and incubated at 37 °C for 24 h. The cells were washed with sterile PBS and treated with coumarin-6 labeled β-Sit-PLGA nanoparticles and incubated for 4 h. To examine thedissolved in dimethyl sulfoxide (DMSO) (200 μL) and incubated for 10 min to allow complete dissolution of the dye. Absorbance was measured at 570 nm using a microplate reader. Control groups included cells treated with blank nanoparticles at equivalent concentrations as the treatment groups (6.64--53.08 μg/mL) and untreated cells.

2.7. Statistical Analysis {#sec2dot7-pharmaceutics-10-00232}
-------------------------

All results are expressed as mean ± standard deviation. Statistical differences between groups were evaluated by one-way or two-way ANOVA and Bonferroni post-tests using a Graphpad Prism, version 5.00, GraphPad Software, La Jolla, CA, USA, 2007. *P* \< 0.05 was considered statistically significant, where applicable.

3. Results and Discussions {#sec3-pharmaceutics-10-00232}
==========================

3.1. Analytical Methods {#sec3dot1-pharmaceutics-10-00232}
-----------------------

A calorimetric method based on the reaction of sterols with acetic anhydride and concentrated sulphuric acid was evaluated to assay β-Sit in a nanoparticle matrix. The


Table S4](#app1-pharmaceutics-10-00232){ref-type="app"}) and later, the optimized parameters were adapted to fabricate β-Sit-PLGA and β-Sit-PEG-PLA nanoparticles. Stigmasterol was chosen as a model for optimization studies due to its similar structure with β-sitosterol; however, it is cheaper and readily available.

Particle sizes were smallest when ethyl acetate was used as the organic solvent compared to acetone and dichloromethane (DCM), respectively ([Figure 1](#pharmaceutics-10-00232-f001){ref-type="fig"}a). This effect can be explained by the partial miscibility of ethyl acetate in water, and therefore by the low interfacial tension which exists between water and ethyl acetate, leading to the formation of smaller nanoparticles \[[@B37-pharmaceutics-10-00232]\]. On the other hand, DCM is immiscible with water, and this creates a very high interfacial tension between the aqueous and organic phases, leading to the formation of bigger-size nanoparticles. Song et al.PEG-PLA used in this study was insufficient to neutralize the surface charge of the PEG-PLA nanoparticles. X-ray photoelectron spectroscopy measurements showed that the surface coverage of PEG chain in PEG-PLA nanoparticles was only 21.11% (ζ = −13.8 mV), compared to 63.73% in PEG-PLA-PEG nanoparticles (ζ = −2.23 mV) \[[@B40-pharmaceutics-10-00232]\]. In other similar studies, the surface charge of PEG-PLGA nanoparticles was comparable to non-PEGylated PLGA nanoparticles (−26.7 compared to −20.9 mV) \[[@B20-pharmaceutics-10-00232]\]. Since PEGylation increases hydration of nanoparticles, this could have resulted in higher surface charge due to consequent hydrolysis \[[@B20-pharmaceutics-10-00232]\]. Unfortunately, β-Sit-PLGA-DCM showed a tendency to aggregate. The scanning electron micrographs show that the particles were spherical in shape with smooth surfaces ([Figure 2](#pharmaceutics-10-00232-f002){ref-type="fig"}A--E), and confirmed the aggregation tendency of β-Sit-PLGA-DCM ([Figure 2](#pharmaceutics-10-00232-f002){ref-type="fig"}C). On the other hand, physicochemical


8, and code generators (CG) 3 and 9. A received signal 1 is converted into an intermediate frequency by the frequency converter 2, and is input to the elastic surface wave element 5. The code generator 3 generates codes obtained by temporally inverting spread codes of the received signal as reference spread codes, and inputs these codes to the elastic surface wave element 5 via the frequency converter 4.
The elastic surface wave element 5 comprises first and second excitation electrodes 102 and 103 for exciting an elastic surface wave on a piezoelectric substrate 101, and a rectangular output electrode 105 arranged between the first and second excitation electrodes 102 and 103.
Each of the first and second frequency converters 2 and 4 comprises an oscillator 15, a multiplier 13,ultimately causes an increase in the accuracy of jump hitting of the ball. The obtained results open the prospects for applying the method of computer stabilography to improve the performance of accuracy-targeted actions in unsupported position in various sports.


25 mm-sized lesion was located just dorsal to the pituitary gland and occupied the preopontine cistern. Differential diagnosis included; craniopharyngioma, pituitary adenoma, neurenteric cyst, dermoid, and RCC.

A pterional craniotomy disclosed a gray-whitish tumor, which was not attached to the infundibulum, and extended up the third ventricle. On approaching the pituitary region, the cyst was observed between the optic nerve and carotid artery. The thin capsule was opened, yellow-whitish mucinous contents evacuated, and the cyst elevated with further dissection. There was no evidence of previous hemorrhage at surgery ([Fig. 2A](#F2){ref-type="fig"}). The tumor was gradually decompressed and totally excised through the space lateral to the carotid artery. The cyst was entirely located behind the dorsum sellae, there was no invasion into the diaphragm.

The patient recovered from the transcranial surgery. Pathologicalfrom 928 test centers. Disease duration was less than 2 years in 29%. 2-5 in 23.2%, 5-10 in 32.5%, and more than 10 in 13.3% (no data for 2%); disease was mild or moderate in 67.4% and severe in 29.9% (no data for 2.7%). Auranofin was given 6 mg/day as either two 3-mg tablets at breakfast or 1 tablet at breakfast and 1 at the evening meal. Laboratory studies and efficacy, as indicated by increase in grip strength and decrease in number of tender and swollen joints, were monitored regularly. A total of 1,595 patients completed 1 year of treatment with AF. Withdrawals included 12.9% for adverse events, 4.2% for insufficient therapeutic effect, and 33.1% for a variety of administrative or technical reasons. The most common adverse event


defendant’s direct
appeal based on the trial record alone); Cooperrider 448 N.E.2d at 454 (holding that when “it is
impossible to determine whether the attorney was ineffective in his representation of appellant
where the allegations of ineffectiveness are based on facts not appearing in the record,”
defendants should avail themselves of post-conviction evidentiary hearing procedures). In these
instances, Ohio effectively requires defendants to raise ineffective-assistance claims in post-
conviction petitions. Indeed, the Ohio Court of Appeals did precisely this in White’s case.
White, 2015 WL 9393518, at *3. Practically speaking, then, Ohio law makes it “virtually
 No. 18-3277               White v. Warden, Ross Correctional Inst.                 AIM felt ephemeral—which probably explained its appeal to Foley. But unbeknownst to most users, the program automatically logged full transcripts of every conversation. It had a permanent memory. If you ended a conversation, a verbatim copy of it would, by default, be saved on your computer.

I first heard about the conversations shortly after Foley initiated them. One of the pages Foley had messaged told me and a few classmates about it. We treated the messages like standard-issue, salacious high school gossip: inappropriate, sure, but nothing too out of the ordinary. When you’re 16, you think of yourself as far older and more mature than you really are—especially when your daily routine involves a full-time job on the floor of the House of Representatives. You don’t feel like a


people do when they walk the halls of his old high school,” writes Stanton. “The capitol, in that sense, is haunted.” | Photos courtesy of Zack Stanton

The article walked a delicate line between reporting what the emails said, and what they meant. Foley’s tone in the emails read like that of a lecherous uncle. He used ellipsis points in place of actual punctuation, as if leaving out the things he really wanted to say:

“I am in North Carolina..and it was 100 in New Orleans...wow that’s really hot...well do you miss DC...Its raining here but 68 degrees so who can argue..did you have fun at your conference….what do you want for your birthday coming up...what stuff do you like to do” [sic]

A later email from Foley got somewhat lesshad transcripts to prove it all.

It didn’t take long before Maddy Sauer, one of ABC’s two reporters working on the Foley case, emailed me back. We exchanged messages.

Maddy Sauer, ABC News, 6:10 PM: I received your email in response to our article on the blotter on Rep. Foley. Please feel free to email me or call me…

Zack Stanton, 6:25 PM: Maddy, As I wrote in the tip, I was a House Page (Democratic) from Sept. 2001 - Jan. 2002. Another page at the time… was getting hit upon by Rep. Foley — both during and after the program (up until 2003, at least). I have some transcripts of various sexually explicit instant-messaging conversations between Joshua* and Foley that took place over that course of time … As you


for Congress, get elected, and relaunch the program. Who is in?” Others suggested a lobbying campaign, or expressed a renewed interest in attending a class reunion.

Ultimately, aside from Mark Foley, only one entity was held responsible and punished for the Foley scandal: the page program itself.

A dozen of us had been planning to meet the following month for a reunion in Shanksville, Pennsylvania, to mark 10 years since the September 11 attacks and pay respects to the passengers of United Flight 93, who, as we now know, literally saved our lives with their heroism. Now, we were compelled to pay our respects to the page program that had brought us together. Nobody else in the outside world quite knows what it was like to be page. In thethe pixel's color, brightness, luminance, and other information associated with the pixel. This image data is susceptible to corruption and noise as a result of data transmission, physical limitations of image capturing and storing devices, electromagnetic interference, etc. To compensate for damage caused to the image data and consequent image degradation, and to reduce the noise and smooth the corrupted image, or merely to enhance the image and emphasize its features, it may be desirable to perform some operations on an image through filtering.
Some traditional but more complicated and often computationally more demanding operations involve transformation of the image data into other domains, such as the Fourier, Hankel, or Hilbert domains, and an inverse transformation to the image domain subsequent to some manipulations in the new domains. Other


don’t like it, but others know you can’t stop it,’’ she said.

‘‘People have to live somewhere and they have kids who will one day grow up and need a home.’’

Residents will seek to ensure adequate services and infrastructure accompany the project.Discourse of power

The discourse of power is used when it comes to differentiating the levels of power due to cultural and social characteristics that come about through societal upbringing. The ways we think and talk about a subject influence and reflect the ways we act in relation to that subject.
The idea of the discourse of power within media has a domino effect and it can play a huge role in determining the patterns of access to the mass media: who has preferential access to journalists, who will be interviewed, who will be quoted and described in news reports, and whose opinions will influence the public? Through access to the mass media, dominant groups also may have access to and partial control over the public at large.

The role of


level of remoteness.

Data relating to the subscription plans participants held were used to determine whether participants enrolled for 12 or 52 weeks. The date of enrollment and the date that membership ceased were used to calculate the number of days each participant was a member of the program and, therefore, how many participants cancelled their subscription. The self-reported weight records were used to describe the number of people who weighed in each week. The self-reported weights (in kilograms) were used to determine the weight change achieved. The total number of days per week each of the website features (log-ins, food diary entries, exercise diary entries, and forum posts) were used was calculated to describe overall website use.

Data Analysis
-------------

Data analysis was undertaken using Stata 11.0 (StataCorp, College Station, Texas,12-week subscribers, only 11% (792/6943) self-reported their weight during their final week of the program (ie, 89% of participants' weight data was missing). For 52-week subscribers, the decline in the number of participants self-reporting their weight was continuous from week 2 (73%) to week 32 (12%). However, after week 32, the percentage of participants self-reporting a weight reached a plateau but remained steady at 9% to 11% until 52 weeks. Therefore, 91% (2412 /2656) of participants' weight data was missing at week 52.

![Percent of participants who weighed in per week for 12- and 52-week subscribers.](jmir_v13i4e83_fig2){#figure2}

Weight Change: Primary Analysis
-------------------------------

Weight change results for 12- and 52-week subscribers are shown in [Table 1](#table1){ref-type="table"}. The GLMM gave a mean self-reported weight reduction for 12-week subscribers of −5.6 kg (95% confidence interval \[CI\]


                         Absolute weight change (95% CI)         −5.6 kg (−5.8 kg to −5.5 kg)   −2.6 kg (−2.7 kg to −2.5 kg)
                                       Percentage weight change (95% CI)       −6.2% (−6.3% to −6.1%)         −3.0% (−3.0% to −2.9%)      this paper was to describe the weight loss achieved by a large cohort of participants who subscribed to a commercial Web-based weight loss program for either 12 or 52 weeks. The study addresses an existing gap in the literature \[[@ref5],[@ref6]\] by reporting weight loss outcomes in a large naturalistic cohort of commercial users of a Web-based weight loss program and its association with website feature usage. This study is one of only a small number of evaluations of commercial weight loss program cohorts and only the second to employ a robust statistical analysis as opposed to reporting results for program completers only. To the authors' knowledge, it is the first cohort study reporting outcomes from a large group of enrollees in a commercial Web-based program.

Weight Loss
-----------

Our primary analysis


Carhaix.

October events
 October 20 – First railway in Taiwan opens from Keelung to Taipei.

November events
 November 30
 John D. Spreckels incorporates the San Diego Electric Railway Company.
 Brooks Locomotive Works completes its 2,000th new steam locomotive.

December events
 December 4 – Great East Thompson Train Wreck: Four trains collide in East Thompson, Connecticut. It is one of the most extensive rail disasters in American history, yet only three people are killed.

Unknown date events
 Geared steam locomotive designs in the United States: Charles L. Heisler builds a working prototype of what is to become the Heisler locomotive and Rush S. Battles patents the basic design of the Climax locomotive.
 Canadian Pacific Railway launches its trans-Pacific shipping route between Vancouver, British Columbia and Hong Kong.
 The Busk Tunnel Railway CompanyOK?" " Yeah." "I overheard a phone conversation." "We have less than 15 minutes." "Have your men secure the floor." "Curtis and I are going after the override." "Stay down!" "Stay down." "Marwan is impersonating a CTU officer." "I repeat, the suspect is impersonating a CTU officer." "Edgar!" "Line one." "Curtis has the override." " (Edgar) The override logged in?" " Yes." "Good." "Send it to channel 11." "Hurry up." "(Curtis) They're starting to respond." " It's working, Edgar." " Yes!" "Yes!" "The temperature is dropping in all remaining power plants." "(Heller) Congratulations, Edgar." "(woman) Ms Driscoll?" "It's about Maya." "You'd better go down to the clinic right away." "Maya?" "Oh!" "Oh!" "Oh, baby!" "No!" " (Edgar) I got new intel." " What?" "The man you're looking for,


Habib Marwan, works for McLennan-Forster." "But they made the override." "He's working under the alias Harris Barnes." "They had no reason to suspect." "He positioned himself inside the company so he could use their technology." "Tell 'em to freeze Marwan's personal files." "I did." "You want me to send a comm team over?" " No, we're closer." "Jack or I'll go." " Sure." "Marwan was in the building within the last 15 minutes." "I want perimeters here, roadblocks in every direction." " Done." " Jack." "I just got off with CTU." "Marwan worked for McLennan-Forster under an alias, Harris Barnes." " I told CTU we'd check it out." " OK." "Take Paul and Audrey back to CTU." "I'll be on my cell." "Castle'll stay in charge here." "Ifcan now purchase safe and effective vegan CBD Oil on Ordinary Vegan. Link here.

I believe CBD oil can help many people living with anxiety disorders or chronic pain and my mission is to provide you with the highest quality CBD oil from hemp on the market. My number one goal is to keep you as healthy and as happy as possible. Learn more about how CBD Oil from Hemp can help you.

Grilled Portobello Mushroom over Mashed Cauliflower with Mushroom Gravy Print Prep time 15 mins Cook time 30 mins Total time 45 mins The mushroom gravy is definitely optional and this recipe tastes delicious with or without it. Here is the link to the rich and delicious mushroom gravy. Author: Ordinary Vegan Serves: 2 Ingredients Grilled Mushrooms 2


the 2004 Olympics the banks were shunting money into Athens at a fast and furious rate, just as in the US they were writing home loans for people who were so broke they couldn’t afford the 10 per cent deposit. Bankers and developers dreamt up schemes for hotel resort projects, defence contracts, infrastructure and high-yield investment funds. Nothing was built that offered jobs, met a social necessity or even created real economic activity. They simply passed the money around between themselves each taking performance fees, bonuses, dividends, salaries, pensions, expenses and superannuation. Sometimes they took out personal loans at risk-free rates for private investment.

Rich Greeks became super rich. Poor Greeks became super poor and many stopped paying taxes because they couldn’t afford to or they refused to.

If every57 + -54. Let a be 0 + -4 + i + 38 + -3. Suppose 4 - a = -2*l. Does 5 divide l?
True
Let v = -7375 - -11485. Does 30 divide v?
True
Let k(a) be the second derivative of a**5/20 - 5*a**4/3 + 23*a**3/6 + 51*a**2/2 - 14*a + 1. Does 2 divide k(19)?
False
Suppose -60 = -34*c + 29*c. Let h = 14 - -222. Does 8 divide h*(15/c + -1)?
False
Let x(q) = -6*q**2 - 133*q - 17. Let i be x(-22). Suppose -k + 3*c + 113 = -469, -4*k - i*c = -2260. Does 10 divide k?
True
Is 62*(5/10 + 5) a multiple of 11?
True
Let f(w) = -2697*w - 407. Is f(-3) a multiple of 34?
True
Let z = 308 + -316. Does 12 divide ((2*z)/4)/(2/(-264))?
True
Let z(x)


-3*c = -8*c + 15. Let y = c - 5. Let r(j) = 2*j**2 + j - 1. List the prime factors of r(y).
5
Suppose 0 = 3*r - 5 - 1. Suppose r*f - 2*t + 6 = -6*t, 0 = f - 4*t - 15. What are the prime factors of f?
3
Let m(z) = 10*z + 3. What are the prime factors of m(3)?
3, 11
Suppose -5*q - 2 = -7. What are the prime factors of ((-3)/(-2))/(q/22)?
3, 11
Suppose 3*a - 802 = -4*l, l + 0*l = -5*a + 1314. List the prime factors of a.
2, 131
Let w be 6/1*(-3)/2. List the prime factors of (2*-2)/(6/w).
2, 3
Let f(k) = 3*k**2 - 3*k + 2. Suppose 5 = 5*t, 0 - 4 = -j - t. Whatz(-9). Let u be g(l). What are the prime factors of (-8)/(-5)*(u - 5)?
2
Suppose 2*m + 32 + 94 = 2*p, -345 = -5*p - 5*m. List the prime factors of p.
2, 3, 11
Suppose 3*o = -2*r + 116, -180 - 89 = -5*r + 3*o. What are the prime factors of r?
5, 11
Let t(k) = 5. Let d(w) = -w + 6. Let i(a) = 4*d(a) - 5*t(a). Let o be i(-2). Suppose m = 1 + o. What are the prime factors of m?
2
Suppose l = -0*l + 3. Suppose -5*q - k = -41, 2*q + 3*k - l = 3. What are the prime factors of q?
3
Let u(z) = 2*z**2 + 3*z. Let i(k) = 2*k**2 + 3*k. Let a(c) = -5*i(c) + 6*u(c).


collective bargaining agreement. There is no provision in the section for any other authorized representative or for individual participation of persons receiving retiree benefits. See § 1114(b)(1), which provides that "[f]or purposes of this section, the term `authorized representative' means the authorized representative designated pursuant to subsection (c) . . . or subsection (d). . . ."
Moreover, the rights of persons receiving retiree benefits are not determined under the creditors' section, 11 U.S.C. § 1109(b). Their rights are established by 11 U.S.C. § 1114. To allow individual retirees to intervene and participate could completely frustrate the effective implementation of § 1114  as evidenced by this appeal.
Since appellants do not have standing to bring this appeal, the other questions raised by the appeal need not be answered. However,*
 * The Original Code is Copyright (C) 2001-2002 by NaN Holding BV.
 * All rights reserved.
 */

/** \file
 * \ingroup MEM
 *
 * \brief Read \ref MEMPage
 *
 * \page MEMPage Guarded memory(de)allocation
 *
 * \section aboutmem c-style guarded memory allocation
 *
 * \subsection memabout About the MEM module
 *
 * MEM provides guarded malloc/calloc calls. All memory is enclosed by
 * pads, to detect out-of-bound writes. All blocks are placed in a
 * linked list, so they remain reachable at all times. There is no
 * back-up in case the linked-list related data is lost.
 *
 * \subsection memissues Known issues with MEM
 *
 * There are currently no known issues with MEM. Note that there is a
 * second intern/ module with MEM_ prefix, for


pointer to the
 * newly allocated block.  */
extern void *(*MEM_dupallocN)(const void *vmemh) /* ATTR_MALLOC */ ATTR_WARN_UNUSED_RESULT;

/**
 * Reallocates a block of memory, and returns pointer to the newly
 * allocated block, the old one is freed. this is not as optimized
 * as a system realloc but just makes a new allocation and copies
 * over from existing memory. */
extern void *(*MEM_reallocN_id)(void *vmemh,
                                size_t len,
                               void (*MEM_set_lock_callback)(void (*lock)(void), void (*unlock)(void));

/** Attempt to enforce OSX (or other OS's) to have malloc and stack nonzero */
extern void (*MEM_set_memory_debug)(void);

/**
 * Memory usage stats
 * - MEM_get_memory_in_use is all memory
 * - MEM_get_mapped_memory_in_use is a subset of all memory */
extern size_t (*MEM_get_memory_in_use)(void);
/** Get mapped memory usage. */
extern size_t (*MEM_get_mapped_memory_in_use)(void);
/** Get amount of memory blocks in use. */
extern unsigned int (*MEM_get_memory_blocks_in_use)(void);

/** Reset the peak memory statistic to zero. */
extern void (*MEM_reset_peak_memory)(void);

/** Get the peak memory usage in bytes, including mmap allocations. */
extern size_t (*MEM_get_peak_memory)(void) ATTR_WARN_UNUSED_RESULT;

#ifdef __GNUC__
#  define MEM_SAFE_FREE(v) \
    do { \
      typeof(&(v)) _v = &(v); \
      if (*_v) { \
        MEM_freeN(*_v); \


Fluid and protein shifts after postural changes in humans.
With the use of a new mass density detection method, blood density (BD), plasma density (PD), and erythrocyte density (ED) were measured during different postures in euhydrated humans. ED remained stable under various head-up tilt (HUT) procedures. Changes of PD and BD mirrored the time course of hemodilution and hemoconcentration. The mass density of the shifted fluid (FD) was virtually identical for the outward filtrated fluid when upright and for the inward movement of fluid when supine; it averaged 1,008.3 g/l (37 degrees C), which is equivalent to a protein concentration of 30 g/l. PD and BD increased almost linearly with increasing angles of tilt. A stepwise increase from supine position to 90 degrees HUT within 2 h resulted inlooking for something like:
$.fn.bindFirst = function(type, handler) {
    return this.each(function() {
        var elm = this;
        var evs = $._data(this).events;
        if ( type in evs ) {
            var handlers = evs[type].map(function(ev) {
                return ev.handler;
            });
            $(elm).unbind(type).on(type, function(e) {
                handler.call(elm, e, function() {


Background
==========

Primary carcinomas of the duodenum, excluding carcinoma of the ampulla of Vater, have been reported to occur in 0.019-0.5% of all autopsies and in 35-45% of all cases of small intestinal cancer \[[@B1],[@B2]\]. There have been few reported cases in the literature of multiple synchronous primary cancers of the duodenum and colon although a large population-based study has suggested that patients diagnosed with primary duodenal carcinoma have a higher than expected incidence of second primary malignancy \[[@B3]\]. We are reporting a case of synchronous duodenal and colonic carcinomas plus a renal oncocytoma successfully resected using a one-stage surgical approach.

Case Report
===========

A 67 year old male presented with a history of weight loss and generalized weakness of 2 months duration. General investigations revealed anemia with hemoglobin of 9.2 g/dl. Uppersuccessfully used for multiple synchronous primary tumors.

Consent
-------

Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Competing interests
===================

The authors declare that they have no competing interests.

Authors\' contributions
=======================

ES drafted the manuscript, AcS and A1S participated in the design of the study, MK assisted with the collection of data and conceived of the study, WF and DM participated in the design and coordination of the study. All authors read and approved the final manuscript


Please note menu options and prices may change at any time. We cannot honor previous prices if an order hasn't been paid and confirmed.

Food Allergies & Intolerances: When ordering, please ask us about the ingredients in our products to ensure no allergens are added. Please note while every caution is taken to prevent cross-contamination, any product may contain traces as our entire menu is produced in the same kitchen.an in depth portrait of who characters are and why they do or say what they do, but even within that envelop the lack of information we have about the women in Pins And Needles is an abyss. Why have Fay (Davis) and Carolyn (Cowden) suddenly decided they are attracted to women? How did they discover this? What is their life like? Do the couples have children and how does/did this affect their realisations and subsequent actions and decisions?

The acting and direction doesn't really help a lot. I didn't get a sense the actors were actually listening to each other and saying their lines in response. There were too many misses of nuance and emphasis for this to be true. They all know their lines and where to


michigan-capitol-wide.jpg

The Michigan Capitol in Lansing as seen in the summer of 2013.

(Jonathan Oosting | MLive.com)

LANSING, MI -- Michigan's Republican-led Legislature on Wednesday approved controversial legislation that will prohibit insurers from paying for abortions unless a woman has already purchased coverage through a separate rider.

The "citizen-initiated" law, backed by Right to Life of Michigan, will take effect in March without crossing the governor's desk or appearing on the statewide ballot next year.

House and Senate leadership took up the measure shortly after 4 p.m., prompting a series of impassioned speeches from opponents, who have called the bill a "rape insurance" proposal because it does not include any exceptions for abortion coverage beyond imminent death of the mother.

Senate Minority Gretchen Whitmer, D-East Lansing, cited the need to put a face onMany of the medical care garments and products, protective wear garments, mortuary and veterinary products, and personal care products in use today are partially or wholly constructed of extruded filamentary web materials such as nonwoven web materials. Examples of such products include, but are not limited to, medical and health care products such as surgical drapes, gowns and bandages, protective workwear garments such as coveralls and lab coats, and infant, child and adult personal care absorbent articles such as diapers, training pants, disposable swimwear, incontinence garments and pads, sanitary napkins, wipes and the like. Other uses for extruded filamentary web materials include geotextiles and house wrap materials. For these applications extruded filament web materials provide functional, tactile, comfort and/or aesthetic properties that can approach or even exceed those


Home automation systems include devices and software capable of controlling building functions such as lighting, climate control, security, and other functions. For example, home automation systems may provide for centralized control of light switches, dimmers, thermostats, heating ventilation and air conditioning (HVAC) systems, building sensors, and other household devices. Typical home automation systems may be operated using “control panel”-type hardware and/or software interfaces that allow a user to manually operate each home automation device. For example, the user may turn on lights by operating various wall switches and/or manually clicking various options in a home automation application executed by a standard computer.
Certain computing devices may implement conversational user interfaces, which may allow for back-and-forth interaction between the computing device and user. For example, a conversational user interface mayknown about the transcriptional regulators that control NO-detoxification process in fungi. In this work we have focused our investigation on the identification of transcriptional regulators controlling nitrosative stress in *C. albicans* using a comprehensive genome-wide screen of mutants for genes encoding TFs as well as components of chromatin remodeling and histone modification complexes. The compiled transcriptional regulatory mutant sets covered approximately 80% (170/213) of the TFs annotated in CGD and 40% (229/500) of proteins annotated to the GO term "regulation of gene expression". This extensive investigation led to the identification of two transcriptional regulators, Cwt1p and Cta4p acting antagonistically in the control of nitrosative stress tolerance in *C. albicans*. Cta4p is a Zn(II)~2~-Cys~6~ TF that plays a dominant role in nitrosative stress resistance through a direct transcriptional activation


up to speed with the workflow, culture, and, and expectations of the institution.

This is often to both the internal candidate’s and the institution’s advantage: they both know each other and are familiar with the expectations of the institution and culture.

However, you should know is that any search process with integrity is going to be competitive. The hiring manager in these situations is looking for the best person to fill the role: regardless of their background: internal or external. The process should be competitive: neither internal or external candidates should believe that they are a shoe-in for the position.

If anything, take solace in the fact that they advertised the position. It’s out there in the wild! That means anyone. Anyone, can apply for it. That includes you. So useReport: CT health exchange premiums among the nation’s highest

By Lisa Chedekel, Conn. Health I-Team Writer

Connecticut consumers who buy insurance on the new exchange will pay some of the highest premiums in the nation, according to a report by the U.S. Department of Health and Human Services released Wednesday.

While the report lauds lower-than-expected prices nationwide, it shows that the premium for a benchmark insurance plan, dubbed a “second lowest cost silver plan,” would cost an average of $436 a month in Connecticut – 33 percent higher than the national average, and fourth-highest in the country after Alaska, Mississippi and Wyoming.

State exchanges, including Connecticut's Access Health CT, will offer “bronze,” “silver“ and “gold” policies that vary in coverage, deductibles and co-pays. Consumers can begin to enroll for insurance on Oct.


that (Connecticut) currently has the 4th highest medical costs in the U.S., underscoring how various marketplace variables impact premium rates.”

Additionally, he said the state has “a substantial number of mandated benefits when compared to other states, as well as broad provider network requirements, both of which tend to drive higher premiums.”

Counihan added: “We look forward to being part of the dialogue to address these important issues moving forward as we look to make coverage more affordable in our state.”appalling amount of labor-saving technologies in use throughout our economy. It is, alas, a disturbing trend that has been around for quite some time – since, really, the invention of the spear which destroyed the jobs of some hunters.

Sincerely,

Donald J. Boudreaux

Professor of Economics

George Mason University

Fairfax, VA 22030

….

(HT my buddy Lyle Albaugh)

UPDATE: My friend Wilson Mixon, from over at Division of Labour, e-mails to me this reaction to my letter to Rep. Lee:

The spear didn’t just destroy jobs. It (and even worse, the bow and arrow) dehumanized the whole process. How much more fulfilling it must have been to take on a boar mano a mano (or mano a colmillo). Think of the empathy and respect between predator and prey that the old fashioned way must have generated. No


even if the court had the power to toll the limitations period, Buerger's request to simultaneously dismiss the case and to toll the statute of limitations is improper in the Fifth Circuit. Buerger has moved for a voluntary dismissal, but at the same time has requested that the statute of limitations be tolled. The Fifth Circuit has held that a plaintiff's voluntary dismissal of an earlier suit without prejudice does not toll a statute of limitations. Taylor v. Bunge Corp., 775 F.2d 617, 619 (5th Cir.1985); see also WRIGHT & MILLER, FEDERAL PRACTICE & PROCEDURE § 1056 (1987). "[T]he effect of [a voluntary dismissal is] to put the plaintiff in the same legal position in which he would have been had he never brought the first suit." Taylor,775 F.2d at 619; see also Basco, 43 F.3d at 965-66. The court finds, therefore, that even if it was proper for it to take any action in this case, it would be improper for it to toll the statute of limitations.
A refusal to toll the statute of limitations in this action does not work any prejudice against the plaintiff, should he wish to refile his suit in state court. The statute of limitations has not yet run against the remaining defendants in this case, Dr. Mayo and Dr. Gol. Plaintiff's first visit to Dr. Mayo occurred on October 23, 1996. Pl.'s Am. Pet. at 2, 7. His first visit with Dr. Gol occurred on November 8, 1996. Pl.'s Am. Pet. at 8. Therefore, Plaintiff has at least


Radiofrequency transmissions may be easily intercepted, in part because of the fact that RF signals are designed to radiate signals in all directions. Radiofrequency transmissions are also regulated by the Federal Communications Commission (FCC) which controls the frequencies that may be used by individuals. Radiofrequency transmissions are also susceptible to interference and produce noise.
In contrast to RF communications, light sources used for communication are extremely secure due to the fact that they are focused within a narrow beam, requiring placement of equipment within the beam itself for interception. Also, because the visible spectrum is not regulated by the FCC, light sources can be used for communications purposes without the need of a license. Light sources are also not susceptible to interference nor do they produce noise that canresponsibilities and extent of information required to manage a building is often quite overwhelming.
One very important area associated with building management is lighting or illumination. While often perceived as a simple task of providing lights, this seemingly simple task has much research and science behind a well-designed lighting system. This is because safety, productivity and general well-being of occupants depend heavily on proper lighting.
Many factors need considered at the time of construction or remodeling to facilitate proper lighting design. Intended usage of a space is important in illumination design consideration, since this will dictate necessary illumination levels, times and duration of use, and anticipated cycling of the illumination. In other words, a supply closet will not ordinarily be designed for around-the-clock illumination, and may instead be configured to


by strong winds, stray animals, passing vehicles, or blowing debris. Inside, they operate only for a specific time; a room's occupant, if not moving about, may suddenly be in the dark and must re-activate the light by waving or flailing about.
An increasingly complex, and therefore hazardous, society requires increasingly extensive patrols and safeguards. Current security system, which must rely on increasing the numbers of guards and security devices, are subject to inherent defects and extraordinary expense, generally rendering them inadequate even with the best of intention.
Yet another very important area associated with building management is guidance control and indication, which impacts building security, as well as building convenience and efficiency for occupants. In buildings having many alternative hallways or paths, such as are commonly found in hospitals andexample, open a couple of Finder windows and then click the Window menu. Focus on the Minimize Window command. Now press Option and watch both the wording and the listed keyboard equivalent change instantly to Minimize All (Option- -M).

The Option key works wonders on the File menu, too.

  * In the bad old days (up to late 2009), minimizing a bunch of documents could get really messy. Each one flew onto the Dock, putting a new icon there, creating a tighter and tighter squeeze, shrinking the Dock's icons until they were the size of Tic Tacs.

Nowadays, your document windows can minimize themselves into their programs' Dock icons, rather than creating new Dock icons for themselves. That way, your Dock doesn't get any more crowded, and the icons


love Photos (and who doesn't?). But one thing drives you crazy: The Revert to Original command, which discards all the changes you've ever made since taking the photo, has no keyboard shortcut. You must trek up to the menu bar every time you need that command.

This is why macOS lets you add keyboard shortcuts to menu commands that lack them—or change the commands in programs whose key assignments break with tradition. (It works in any program that uses the standard macOS menu software, which rules out older versions of Microsoft Office.) Here's the routine:

  1. **Choose**   → **System Preferences** → **Keyboard. Click the Shortcuts tab, and then click App Shortcuts in the left-side list.**

You're shown a list of any keyboard assignments you've created so far.

dial a number that's not already in Contacts. The workaround: Create a temporary fake person in Contacts!

###### Figure 9-2. To make Mac dialing work, the iPhone and Mac must be on the same Wi-Fi network. They both have to be signed into the same iCloud account. And you have to open the FaceTime settings on each device and make sure they're both set to use the same iCloud account.

## And if It's Not Working

"It just works" is fantastic—when it just works.

If your Mac isn't able to send and receive calls and texts through your phone, here's the checklist. One of these things, you'll discover, isn't set correctly.

  * **The iPhone and Mac have to be on the same network** (for example, the same Wi-Fi network).

##### Note

Actually, iOS


Mac automatically starts searching for nearby Bluetooth gadgets within range (see Figure 10-12, bottom)—nearby headsets, laptops, cellphones, and so on. Usually, it finds the one you're trying to pair. Just click the one you want, and then click Pair.

When it's all over, the new gadget is listed in the panel, in the list of Bluetooth stuff that you've previously introduced to this Mac. (You can click it and then click   to get rid of the pairing, when that day comes.)

A few footnotes:

  * If you're pairing a mobile phone or something else that has a keypad or a keyboard, the Mac may display a large, multiple-digit _passcode._ It's like a password, except that you'll have to input it only this once, to confirm that _you_either a mirror of your Mac's screen or an extension of it.

You can present photo slideshows on the TV from your laptop. Or play movies you've found online. Or give presentations from PowerPoint or Keynote. Or present software lessons to a class.

This trick requires both a Mac made since mid-2011 and an Apple TV. That's a tiny black box that connects to a high-def TV and lets you watch videos from services like YouTube, Netflix, MLB.TV, NBA, NHL, and Vimeo. It can also play videos, music, and photos from Macs or PCs on the network.

But with AirPlay, the Apple TV (and therefore your TV) can now play anything you can see on your Mac. You can play your iTunes music while watching those cool screen-savery visualizers on your


interested in finding out where you are; often, you know that much perfectly well. Instead, you want to see where something _else_ is. Click in the search box and type what you're seeking—or, if you spot what you want in the list of recently sought addresses, click it there. (If there's already something in the box, then click   to clear it out.) Here's what Maps can find for you:

  * **An address.** You can skip the periods (and usually the commas, too). And you can use abbreviations. Typing _710 w end ave ny ny_ will find 710 West End Avenue, New York, New York. (In any of these examples, you can type a zip code instead of a city and state.)

  * **An intersection.**of the biggest-ticket items in Mac OS High Sierra is the Apple File System (APFS), developed for the new era of solid-state drives and increased security threats. It's standard across all of Apple's gadgets: macOS, iOS, tvOS, and watchOS.

All of this is very satisfying to programmers. But you, the average person, will probably notice only a couple of changes.

First, when you duplicate a file or folder on an APFS drive, it happens instantly. There's no progress bar, no waiting—and the copy takes up almost no space, at least until you make changes to it.

Second, getting the size of a folder ("FREQUENTLY ASKED QUESTION Calculate All Sizes") is also instantaneous.

There are a few things to note as you enter the exciting new world of APFS, though. First, macOS High


choosing its name from this pop-up menu.

  * **Copies.** Type the number of copies you want printed. The Collated checkbox controls the printing order for the pages. For example, if you print two copies of a three-page document, the Mac generally prints the pages in this order: 1, 2, 3, 1, 2, 3. If you turn off Collated, on the other hand, it prints in this order: 1, 1, 2, 2, 3, 3.

  * **Pages.** You don't have to print an entire document—you can print, say, only "A New File System" through 15.

##### Tip

You don't have to type numbers into both the From and To boxes. If you leave the first box blank, the Mac assumes that you mean "From Chapter 1." If you leave thesynchronize all of it (passwords and credit cards) with your other Apple phones, tablets, and Macs.

## Memorized Contact Information

To turn on this great feature, visit the Safari→Preferences→AutoFill tab. If you turn on "Using info from my contacts," then whenever you're supposed to fill in your shipping address on a web form, you can click the AutoFill button in the address bar to have Safari fill in the blanks for you automatically. (If you don't see the AutoFill button, then choose Edit→AutoFill Form to do the deed instead.)

Alternatively, just click a text box—Name, for example—and start typing. As soon as Safari recognizes a familiar scrap of your contact information, it displays a pop-up suggestion below the text box. To accept the suggestion, click it (or press the


told by investors that they had to clean up their image. So they
hired Pao, had her make the changes (banning a few obnoxious subs, updating
site code of conduct), and then fired her (without rolling back the changes)
to appease the more vocal members of the community.

~~~
dukeluke
Catering to the lowest common denominator is a large reason why the quality of
news networks have tanked in the last decade. Why wouldn't the same drop in
quality occur with Reddit?

------
apsec112
Hey, OP here. I don't really care about Pao, but posted this again because of
the details it provides on how the NYT operates in general. In particular,
there's this paragraph:

"I often hear from readers that they would prefer a straight, neutral
treatment — just the facts. But The Times has moved away from that, reflecting
editors’ reasonable beliefassociations with a variety of study designs [@bb0060], [@bb0065], [@bb0070].

Given the wide disparity in outcomes among women with ULMS and the lack of benefit from adjuvant therapy, we performed gene expression profiling on a homogeneous, single-institution set of ULMS without inclusion of tumors from non-gynecologic sites of origin. We tested the hypothesis that ULMS has distinct molecular subtypes that are associated with clinical outcome and may identify therapeutic targets.

Methods {#s0010}
=======

Patient Samples {#s0015}
---------------

Frozen and archival formalin-fixed and paraffin-embedded (FFPE) biospecimens were obtained from the tissue repositories at Memorial Sloan Kettering Cancer Center (MSKCC) after Institutional Review Board approval. A gynecologic oncology specialty pathologist reviewed all primary surgical resection specimens. NL and leiomyomata from patients undergoing hysterectomy for benign indications were used for comparison. A discovery cohort of fresh frozen


with coordinated biospecimen collection.

Appendix A. Supplementary data {#s0070}
==============================

Table S1. Differentially Expressed Genes between ULMS and NL, FDR \< 0.0001Table S2. Differentially Expressed Genes between Two ULMS Clades, *P* \< .001Table S3. Overexpressed Genes in Validation Samples of ULMS Compared to NL, Bonferroni Corrected *P* \< 4.4 × 10^--4^. The Results from the Discovery Samples Are Shown for Reference Only to Indicate a Similar Extent and Direction of Differential ExpressionTable S4. Top 10 Gene Sets Enriched for Genes Upregulated in Tumor *versus* Normal Samples. Adjusted *P* Values Are Bonferroni Corrected for 2234 Gene SetsTable S5. Top 10 Gene Sets Enriched for Genes Downregulated in Tumor *versus* Normal Samples. Adjusted *P* Values Are Bonferroni Corrected for 2234 Gene SetsTable S6. Top 10 Gene Sets Enriched for Genes Upregulated in TumorPhoto: Matthias Clamer

Over dinner at The Four Seasons, Brian Williams takes off his regimental tie and discusses his burgeoning side career in comedy. The evening we meet, protests are still roiling the streets of Cairo, Libya is descending into civil war, and the NBC Nightly News anchor is coming off a reporting trip to Egypt. He has also just finished a two-week stretch in which he visited The Daily Show, Letterman, and Late Night With Jimmy Fallon. There are full-time comics who would trade their rarest Lenny Bruce record for just one of those bookings.

Williams has been honing his act for some time—the first of many entertaining appearances on Conan’s Late Night occurred back during the Clinton administration—but it’s only recently that he’s shown how funny he can


the season-four episode “Audition Day,” he learns that TGS is holding tryouts for a new cast member and throws his hat in the ring. He bombs. “Have you ever wondered what happens in the refrigerator after the light goes off?” he asks during his audition. “Does the milk say, ‘Let’s go down to the crisper drawer and make trouble’?”

Consider the complexity of that brief scene: It’s Williams doing “Williams” doing bad Seinfeld. The anchor’s cameos are not merely a matter of dropping by the 30 Rock set, reading a line, and dashing back to the safety of the newsroom. He’s pushed onto the sitcom’s high-wire and expected to keep his balance like everyone else.

Told of Meyers’s appreciation for his “comic instrument,” Williams replies, “That’s odd. We’ve never belongedto a health club together.”

It helps that Williams is a student of the form. Fey accuses him of having “a nerdy obsession with comedy,” the kind you typically find among comedians. Williams confesses that while he dreamed of being Cronkite as a kid, he stayed up to watch Carson every night he was allowed to. He pored over the work of Pryor and Kinison. He sent away for Saturday Night Live tickets after watching the premiere episode. (He got them and attended a season-two episode that, according to Williams, Lorne Michaels still considers one of the worst nights in the show’s 36-year run. Broderick Crawford hosted.)

Williams told me he occasionally marks up 30 Rock scripts because the material they want him to do is too risqué. Fey confirmed