turbine in the Proven range, designed specifically for users with high energy needs who want to offset their carbon emissions.

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Our batteries have Xtreme thick plates with (XC Diamond Plate Technology) added to them. They have been designed for hours of heavy discharge each day, followed by a fast recharge during the daylight hours. Very few batteries can take the grueling deep discharge-recharge cycle every day for long periods of time. U.S. Battery has proven time and time again that our solar battery line can stand up to this type of battery torture day in and day out for years to come. When you demand reliable energy storage count on U.S. Battery every time!fighters. This free action game is not for players who want action even before they start the game. It requires quite some learning. There are many tricks a ninja like you has to master before he is ready to take on some of the most dangerous black ninja fighters. ...

3.

Flying Stickman Ninja - Cool Asian Hero -
Mobile/Games... Stickman Ninja is just minding his own business, flying over a beautiful landscape when, out of nowhere, his enemies attack!
Stickman Ninja needs your help in defeating his foes! Use your ninja stars or 'shuriken' to shoot the enemies. Dont worry about running out of stars because they are UNLIMITED! As you fight your way against your enemies, remember to collect the coins lying around the game. Use the coins to unlock


feature to ensure directors are protected.

Additionally, getting director buy-in from the start is crucial. It is important that boards realize what could happen if their emails are hacked and why they need to adopt secure communications avenues.

Providing your board of directors with the right reasons for needing secure communications is half the battle. Make sure your bank properly evaluates the various technologies to ensure that they will have the right training to properly leverage the tools.

Nicholas Price is the content marketing manager at Diligent Corporation. With a career that has focused on digital marketing, Nick’s specialization is in content marketing and content creation. Nick has worked in the board portal space for two years, which has enabled him to gain a better understanding of the needs of boardroomsDPI (1 μM), or NAC (10 mM) (Figure [6](#F6){ref-type="fig"}B). To determine whether BK enhanced AP-1 transcriptional activity, a promoter containing AP-1 binding sites reporter construct was used. The data showed that BK stimulated an increase in AP-1 promoter activity which was significantly inhibited by pretreatment with BAPTA/AM (30 μM), TG (1 μM), Gö6976 (1 μM), Apo (10 μM), DPI (1 μM), or NAC (10 mM) (Figure [6](#F6){ref-type="fig"}C). To further confirm the role of AP-1 in BK-induced MMP-9 expression, cells were transfected with c-Fos or c-Jun siRNA. The results showed that transfection with c-Fos or c-Jun siRNA significantly knocked down respective c-Fos or c-Jun proteins and attenuated BK-induced MMP-9 expression (Figure [6](#F6){ref-type="fig"}D). These results suggested that BK stimulates AP-1 (*i.e.* c-Fos and c-Jun) activation via the PKC-α-dependent Nox2/ROS generation,


injuries not only causes oxidative damage to cellular macromolecules, but also modulates the pattern of gene expression through functional alterations of transcription factors. The transcription factor AP-1 is well known to be modulated during oxidative stress associated with inflammatory diseases \[[@B36]\]. Moreover, BK-induced gene expression has been shown to be mediated through one of transcription factors such as AP-1 \[[@B18]\]. However, the mechanistic connection between the MMP-9 expression and the ROS-dependent pathway induced by BK has not been established in RBA-1 cells. In this study, we demonstrated that AP-1 is essential for BK-induced MMP-9 expression which was inhibited by an AP-1 inhibitor TSIIA (Figure [6](#F6){ref-type="fig"}A). The involvement of AP-1 in BK-induced responses was further confirmed by determining induction of AP-1 (c-Fos/c-Jun), including phosphorylation of c-Jun, accumulation of c-Fossame way. After infusion, the needle was slowly removed. The burr hole was sealed with bone wax and the incision was closed. Rectal temperature was controlled within the normal range (37±5°C) during surgery with a homeothermic blanket. The animals were maintained at 25°C with ad libitum access to food and water. To evaluate the involvement of ROS in BK-induced MMP-9 expression, the rats were pretreated with a ROS scavenger NAC (150 mg/kg, i.v.) for 1 h before the BK injection for 24 h. To examine the MMP-9 expression and astrocytes' localization in brain cortex, immunofluorescence staining was performed on the first and second serial sections of the brain, which were deparaffinized, rehydrated, and washed with PBS. Non-specific binding was blocked by preincubation with PBS containing 5% BSA for


     where ra.parent = a.child
  )
select * from ranimals;

It fails with the following message:
ERROR:  syntax error at or near "ranimals"
LINE 12:   recursive ranimals as (

Why?

A:

The syntax is confusing.  The clause is with recursive for the entire with.  recursive is not a modifier on a given CTE.  So, try this:
with recursive
  animals as (
    select *
    from (values
      ('cat', 'feline'),
      ('feline', 'mammal'),
      ('dog', 'canidae'),
      ('canidae', 'mammal'),
      ('mammal', 'animal')
    ) as t (child, parent)
  ),
  ranimals as (
    the “organization”, that had been wasting a lot of our time, especially in the couple of years leading up to the release of The Great Deceiver. From that moment on, you could almost physically feel the shifting of gears and actual forward movement.

Michael: More specifically, are you pleased to see your old work coming back to prominence so many years later?

Mortiis: To be honest I think it´s cool that people like my music, regardless of when it was made. I just think it´s cool to see people dig my stuff…I didn´t always feel this way…A few years back, I wanted people to feel the way I did, which was, invariably, that my latest music was the best…That´s not realistic, obviously. But I wanted things to be like that.


for years. Jouni, from In Slaughter Natives, I worked with a few years ago on mastering some of my music, so it hadn’t been that long since we´d last met, but of course it is always nice to meet Jouni. The experience was cool, I mean kind of scary, since it was my first Era 1 show in about 18 years, and I was doing things a bit different than the past anyway, so in a sense this was almost like a debut show. I think a lot of people got into it, but of course CMI attracts a lot of somewhat elitist types, with very specific tastes and with strong opinions on what they like and don´t like, so I think there was a clique of guysapplication, the Tribunal a need a 18 by evidence (Spouse)visa: and provided 2 had supported the when victim review

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developing AI to break into systems and cause havoc. While the white hats are researching ways in which an AI can defend networks against its own kind.

Here’s where we get to the moral question: should we be using AI for these means? As a technology, we’re only beginning to understand its potential. Theoretically, AI could grow so intelligent that it becomes something completely beyond our control.

That thought makes the idea of an AI arms race sound particularly dangerous. Thankfully, intelligent people — Elon Musk and Stephen Hawking included — are thinking carefully about this topic, and I’m confident that they’ll come up with the necessary safeguards. Plus, companies such as Google and Microsoft have already stated that they feel the opportunities outweigh the risks.

Those opportunities are worth noting.54 Pages Posted: 16 Jun 2015

Date Written: January 9, 2015

Abstract

Quarantine remains an important part of the strategy for containing infectious diseases, especially when there is no vaccine or demonstrably effective treatment. Experience with SARS and, more recently, Ebola indicate that quarantine is fraught with ethical challenges. In the United States, legislation authorizing quarantine has been enacted in every state, and these laws have been upheld by the Supreme Court. The problems have been in identifying when quarantine is necessary and in implementation. The following ethical principles should guide public health officials in deciding whether and how to impose a quarantine: (1) necessity, effectiveness, and scientific rationale; (2) proportionality and least infringement; (3) humane supportive services; and (4) public justification.


Japan to get Crystal White Vita

Sony’s mobile gaming system Vita is set to enter more fashion-aware waters as the company announced a Crystal White model for June 28.

The word is the 3G version will go for ¥29,980 (about €289/$375) while the standard WiFi only version will cost ¥24,980 (around €240/$313). This is apparently the same as for the regular, black version, so it’s at least refreshing to see a company not charge extra for make-up alone.

The accompanying Crystal White headphones for Vita will also launch on June 28 and will cost ¥2,800 (about €27/$35). There’s no word on when the rest of the world can expect the Crystal White version, but we suspect it should not take long.+ 4*n - 2. Let u be 0/5*(-1)/(-2). Suppose -2*q + 4*q + 8 = u. Let j(w) = w - 1. Let f be -5*(2/(-10) + 0). Calculate f*x(h) + q*j(h).
2*h**3 + 2
Let t(h) be the first derivative of -5*h**4/4 - 7*h**2/2 + 7*h - 289. Let n(c) = -2*c**3 - 3*c + 3. Let k = -6 - -9. Calculate k*t(p) - 7*n(p).
-p**3
Let q(n) be the third derivative of -7*n**5/60 + n**4/6 - 2*n**3/3 + 30*n**2. Let w(s) = -13*s**2 + 9*s - 9. Calculate -9*q(i) + 4*w(i).
11*i**2
Let b(m) = -m + 1. Let a = 739 + -737. Let v(g) = 10*g - 1. Give a*b(d) + v(d).
8*d + 1
Let x(w) = 3*w + 7. Let h(f) = -9*f - 20. Let o be (17*(-10)/15)/((-4)/(-6)).


interface is simple and intuitive.

Its off-chain matching engine is powerful but never takes control of your assets.

It provides the most sophisticated analytical tools plus complex order types.

Provides a one-click buy and sell operation.

Supports buying and selling of virtual assets across a number of blockchain platforms.

Supports buying and selling using fiat although this option is provided through a partnership with third parties.

The Launch of Nash

Fabio C Canesin, the co-founder of the Nash exchange, has been quoted saying that the platform will officially start operating by the end of March this year. He said this while presenting the ‘Distributed Finance for Everyone’ presentation during this year’s NEO Devcon.

During the announcement, the co-founder affirmed that Nash will be a financial platform for digital economies and will solve the problems that havecompanies, which have access to huge sums of capital and could refit their sprawling networks to carry television, are at present barred from the cable industry.

From the beginning, the National Cable Television Association has tried to fight restraints with a delicate and often cagey minuet.

It quietly supported a standard requiring the presence of six broadcast channels, but it adamantly fought and defeated an additional test requiring that cable companies sign up no more than half the potential subscribers in its market.

But that was precisely the standard deemed most important by consumer groups and local government officials, who have faced a deluge of complaints from their communities about rising cable prices.


to it. My husband has supported me.”

The group cheered – men a little louder than the women – for this empowerment in action!

The attitude of these people had changed since the program started about two years ago. An internal transformation was happening. Personal responsibility for health was seeping into their awareness , which was an assurance for good health but not a guarantee. They could still lose the war, just when they were about to win the battle. They were vulnerable to external forces of socio-politics of man and nature. Unknown to them and beyond their control, people of the world, who had already “progressed” were collectively already destroying their future. The bellowing industrial carbon dioxide had already made the planet into a hot green house and punched1. Field of the Invention
This present invention relates to semiconductor chips and their alignment and fixing to another chip or substrate. The invention relates specifically to a method and apparatus for gracefully degrading performance of a proximity communication channel in response to misalignment of one or more semiconductor chips.
2. Related Art
Proximity communication (PxC) is a well known technology that enables communication between two integrated circuit chips, but that also relies upon face-to-face alignment of those chips, as has been explained by Drost et al. in “Proximity Communication,” IEEE Journal of Solid-State Circuits, vol. 39, no. 9, September 2004, pp. 1529-1535. Misalignment between these two chips between which the proximity communication channel is formed may occur for a number of reasons, including but not limited to: inaccurate placement in


to Harris et al. Although such actuators may be effective in some situations to correct misalignment, they are often difficult and expensive to implement.
However, the prior art has failed to teach a method of gracefully degrading the link performance in response to chip misalignment without necessarily realigning the chips. This degradation may take the form of slowing down the data rate of the channel, increasing the latency in the channel, or increasing the power used by the channel.gathering of amazing people was that it was a lot of business leaders. What about the real people? I intentionally said during our introductions that I’m just here to represent my people,” Moreno said.

Related Content Whitmer will lobby GOP leaders on LGBTQ rights bill

She felt the discussion targeted businesses.

“And that’s fine, but where’s our space then?” she said.

She said Whitmer missed an opportunity to hear about the struggles real people face.

“A lot of my earlier years as a professional, I had to hide who I was. I couldn’t bring my partner to any of my work parties or gatherings,” Moreno said.

When she did go out with her partner, she would introduce her as her best friend.

“We’re trying, but trying is not good enough. There needs to be a


demonstrate that PEGylated polyelectrolyte coatings can effectively alter the fluorocarbon nanodroplet surface properties to reduce coalescence and its uptake into phagocytic cells in comparison with non-PEGylated polyelectrolyte coatings and uncoated nanodroplets, as measured by flow cytometry and fluorescence microscopy. In this study, perfluorooctyl bromide (PFOB) was used as a representative fluorocarbon material, and PEGylated PFOB nanodroplets with diameters between 250 and 290 nm, depending on the poly(ethylene glycol) block length, were prepared. The PEGylated PFOB nanodroplets had superior size stability in comparison with uncoated and non-PEGylated polyelectrolyte nanodroplets in saline and within macrophage cells. Of significance, non-PEGylated nanodroplets were rapidly internalized by macrophage cells, whereas PEGylated nanodroplets were predominantly colocalized on the cell membrane. This suggests that the PEGylated-polyelectrolyte coating on the charged PFOB nanodroplets may afford adjustablecompiled and referred to as SNP-Poly ([S4 Table](#pone.0160463.s006){ref-type="supplementary-material"}).

Translational Optimal codons and Non-optimal codons {#sec006}
---------------------------------------------------

According to the studies of Watkins *et al* \[[@pone.0160463.ref004]\] and Frenkel-Morgenstern *et al* \[[@pone.0160463.ref008]\], the following codons were characterized by low codon---anticodon affinities and defined as non-optimal codons: `GCA,GCT,AGA,CGA,CGT,AAT,GAT,TGT,CAA,GAA,GGA,GGT,CAT,ATA,ATT,CTA,CTT,TTA,AAA,TTT,CCA,CCT,AGT,TCA,TCT,ACA,ACT,TAT,GTA,GTT`.

The other codons were defined as optimal codons: `GCC,GCG,AGG,CGC,CGG,AAC,GAC,TGC,CAG,GAG,GGC,GGG,CAC,ATC,CTC,CTG,TTG,AAG,ATG,TTC,CCC,CCG,AGC,TCC,TCG,ACC,ACG,TGG,TAC,GTC,GTG`.

The classification of optimal and non-optimal codons was based on the binding free energy between codons and anticodons at translational stage, the set of optimal codons in chimp was identical in *Homo sapiens* and *Pan troglodytes*.

Analysis of human cellular signaling network {#sec007}
--------------------------------------------

The human signaling network dataset was downloaded from [www.bri.nrc.ca/wang](http://www.bri.nrc.ca/wang) \[[@pone.0160463.ref028]\]. The nodes with 'activation' and 'inhibition' regulatory relationships were retrieved. After transforming the gene names to ensembl genes ids, a total of 5405 genes with somatic mutations in


large network and the other 23 enzymes in 5 small clusters. The large connected network contained 1826 directional interactions and 899 bi-directional interactions. For directional interaction, the metabolite was the substrate or product of particular enzyme. For the bi-directional interaction, the metabolite was used as substrate as well as product of the same enzyme.

Degree was an important measure of the importance of biological network. For metabolic network with directional interactions, the topological centralities were used to measure the importance of nodes in the control of information transfer. In-degree referred to the number of links forwarded to the considered nodes, out-degree referred to the number of links outwards from the considered nodes, and the nodes with relatively higher degrees are termed as hubs.

Proto-Oncogenes and Tumor repressors {#sec010}
------------------------------------

The proto-oncogenes weredatasets (see [Methods](#sec002){ref-type="sec"}**)**, and found that genes with accumulation of non-optimal codons tended to be differentially expressed in cancers (p = 5.60e-16, *Chi-square*, *two-tail test*) ([Fig 4a](#pone.0160463.g004){ref-type="fig"}), and had a significantly higher average number of differential expressed tissues (p = 1.64e-9, *Mann--Whitney U*, *two-tail test*) ([Fig 4b](#pone.0160463.g004){ref-type="fig"}).

![Function analyses of genes with and without accumulation of non-optimal codons.\
**(a)** Proportion of differentially expressed genes in cancers. The red box represents the proportion of differentially expressed genes in the genes with accumulation of non-optimal codons, the blue box represents the proportion of the proportion of differentially expressed genes in genes without accumulation of non-optimal codons. The p-values were estimated by *Chi-square*, *two-tail test*. **(b)** Number of cancer types for differentially expressed genes. The red box represents the number of differentially expressed


the percentage of genes involved in cellular signal transduction network, the p-values were estimated by *Chi-square*, *two-tail test*. The N1 represents the number of genes without accumulation of non-optimal codons, and the N2 represents the number of genes with accumulation of non-optimal codons. (d) The comparison in the number of regulatory partners, the average number was represented and the p-values were estimated by *Mann--Whitney U*, *two-tail test*. The N1 represents the number of genes without accumulation of non-optimal codons in the signal transduction networks, and the N2 represents the number of genes with accumulation of non-optimal codons in the signal transduction networks. The genes with accumulation of non-optimal codons were sampled to have a similar average proportion of optimal codons with the genes without accumulation of non-optimal codons.

(TIF)

######Very sad news, 40 is really no age at all is it. I knew he has some rare kidney condition, but had no idea it was so serious. The guy was incredible. I still remember those images of him literally running through, and over the top of Mike Catt at the rugby world cup in South Africa and thinking 'who the fuck is this guy, and how the hell do you stop him'. A sad loss.


Q:

Understanding why single-variable expansion of modular arithmetic is valid.

I was reading: https://arxiv.org/pdf/1206.5114.pdf page 10 and came across an odd theorem.
It states, that the system:
$$ \begin{matrix} 2x_1+ 3x_2  \equiv 1 \mod 5  \\ 3x_1 + 5x_2 \equiv 1 \mod 7 \end{matrix} $$
Can be "re-written" as:
$$ \begin{matrix} 2x_1+ 3x_2 +5x_3 =  1   \\ 3x_1 + 5x_2 + 7x_3 = 1  \end{matrix} $$
Now what exactly is meant by "re-written here?" is it that for every solution in the first system there exists a solution in the second system? Or that for every solution in the second system there exists a solution in the first system? Or both?
I find at least the notion of "BOTH" to be impossible. For the simple-2*c - 5*p + 97 = 0, -7*c + 12*c - 199 = 2*p. Let z be d(c). Solve -z*b - 7 = -1 for b.
-2
Let c(u) = -u**3 + 10*u**2 - 24*u + 20. Let g be c(6). Suppose -4*o - k + g = 0, 5*o + 5*k - 39 = -14. Solve o*d = 3*d for d.
0
Suppose -5*i - 25 = 0, 2*i = -4*k - 3*i + 35. Solve -10*r - k*r = -100 for r.
4
Let d(t) = -t**2 + 49*t + 2113. Let j be d(-27). Solve -594 = j*f - 45 for f.
-9
Suppose 18 = -3*f, v - 4*f = 6*v - 676. Solve 138*b - 16 = v*b for b.
-8
Let s(p) = -p**2 - 28*p - 14


Premium Health News Service

The better way to discipline children

Premium Health News Service September 18, 2019

Harvard Health Blog

It may be the toughest part of parenting: learning how to discipline children.

As all parents know, or figure out, raising children isn’t just about feeding, changing diapers, sleepless nights, hemorrhaging bank accounts or general chaos. It’s about raising them to be safe, kind, respectful and productive human beings.

The word “discipline” literally has its roots in the Latin word disciplinare, to teach or train. Parents need to teach their children good behavior; it doesn’t just happen. And it is incredibly hard work, especially because when children act badly, it can get on a parent’s last nerve and trigger an angry response, like yelling or spanking.

According to a policy statement (Effective Discipline to Raiseway to approach discipline is in a loving, proactive way. Teach the rules ahead of time, rather than waiting for your child to break them and reacting then — and be as positive and empowering as you can. Here are some tips:

–Have realistic expectations. Babies are going to cry, toddlers are going to get into things they shouldn’t, school-age kids sometimes lie to avoid trouble, and teenagers — well, they do all sorts of things as they assert their independence. Not that you have to ignore or condone these behaviors (well, you might have to just deal with a baby crying, that’s not misbehaving), but it’s important to understand the stage your child is going through as you discipline. At each checkup with your pediatrician, talk about what


palatable.
One low calorie food ingredient that has met with acceptance is polydextrose. Polydextrose is a low-calorie food ingredient typically used as a bulking agent to replace higher caloric food ingredients (e.g., sugars, fats) in food compositions. In general, polydextrose is a randomly bonded condensation polymer of dextrose and polycarboxylic acids (e.g., citric acid). There are a variety of polydextroses and these different polydextrose modifications can have different properties as food additives.
Polyols such as sorbitol (D-glucitol) and mannitol have widespread commercial application and are commonly used food ingredients. As a group the acyclic polyols are crystalline bodies covering a wide range in melting point and in taste ranging from faintly sweet to very sweet. The polyols commonly used in foods range in caloric availability from essentially fully caloric (sorbitol)posting how strong and confident she is feeling after her water has been broken for 36hrs, and she has had no contractions - no one is allowed to offer support: no women in active labour posting. What if she is posting because she is looking for a good song to listen to while she labours: no posting because she is in active labour. The quote from the recent closed thead is "we can no longer host threads for individuals in active labour"

So even though I disagree with what you said Champagne, the ban just isnt on adivce seeking - its on women in active labour posting. So not only do I disagree with the advice thing, I also think its wrong that women in labour cant seel support


I am now not going to be allowed to seek out the information I am looking for, because there is an assumption that I can not be responsible for how I choose to use that information.

These changes are very disappointing and I am surprised by them. I thought the UA was already clear on the subject. That these are personal opinions and should never be taken as gospel or instead of a trusted HCP. That you as the poster are ultimately accountable for your own choices and reactions to posts. It seems that we are veering down a slippery slope where soon we will all need a legal document signed before we open our mouths , or keyboards so to speak.

Okay I hope that sounded clear. I am       is_near(in_normal.x, out_normals[i].x) &&
        is_near(in_normal.y, out_normals[i].y) &&
        is_near(in_normal.z, out_normals[i].z)
        ) {
        result = i;
        return true;
    }
}
return false;
}

All credit for the functions above goes to:
http://www.opengl-tutorial.org/intermediate-tutorials/tutorial-9-vbo-indexing/
Could this be a:

Visual Studio Community 2015 issue?
VSC15 Debug Mode issue?
Slow Code? (But it's only slow in Debug?!)

A:

There are multiple things that will/might be optimized:

iterating a vector with indices [] is slower than using iterators; in debug, this certainly is not optimized away but in release it might
additionally, accessing a vector via [] is slow because of runtime checks and


to six decimal places?
0
What is 0.0005839594 rounded to 4 dps?
0.0006
What is 2369.61712 rounded to the nearest integer?
2370
What is 0.000697760917 rounded to 7 decimal places?
0.0006978
What is 1249.8481982 rounded to the nearest one hundred?
1200
What is -0.015007187 rounded to 2 decimal places?
-0.02
What is -635.5744 rounded to the nearest integer?
-636
Round 13702516.61 to the nearest 1000000.
14000000
What is -241.83212 rounded to the nearest 10?
-240
Round -0.000008438827419 to six dps.
-0.000008
Round 13686.156 to the nearest one hundred.
13700
What is 13.875224 rounded to 0 dps?
14
What is 0.126587323 rounded to 3 decimal places?
0.127
Round 121.5332146 to the nearest integer.
122
Round -1.1466309 to three decimal places.
-1.147
What is -0.134694043 rounded to 1 dp?
-0.1
What is 105.23578475 rounded to three decimal places?
105.236
Round -10.52963011 to four dps.
-10.5296
What is -331841662.7 rounded to the nearest 1000000?
-332000000
Round -3195842.66 to the nearest one thousand.
-3196000
Round -0.00000078945908 to seven decimal places.
-0.0000008
What is -0.0000086021985{
       margin: 5px 0 0;
     }
  }

  .line {
    display: flex;
    flex-direction: row;
    justify-content: space-between;
    border-bottom: 1px solid @color-basic-100;
    border-top: 1px solid @color-basic-100;
    padding: 5px 0;
    align-items: center;
    min-height: 44px;

    &-description {
      width: 100%;
      padding: 13px 16px;
      border-radius: @border-radius;
      background: @color-basic-50;
      margin-top: 4px;
      border: 1px solid @color-basic-100;
    }

    &-no-border {


Background {#Sec1}
==========

Multiple endocrine neoplasia (MEN) is a general term for two or more endocrine glands with tumor lesions. According to its clinical manifestations and types of mutation, this condition can be divided into MEN1 (Online Mendelian Inheritance in Man (OMIM) number: 131100), MEN2 and familial medullary thyroid carcinoma (FMTC) (OMIM number: 155240). Furthermore, MEN2 also has two subtypes: MEN2A (OMIM number: 171400) and MEN2B (OMIM number: 162300). MEN2B is a rare autosomal dominant genetic disease caused by a mutation of the *RET* proto-oncogene. The main clinical manifestations are medullary thyroid carcinoma (MTC), multiple mucosal neuroma, pheochromocytoma (PHEO), and Marfan-like habitus \[[@CR1]\]. The overall incidence of MEN2B is approximately 1:35,000 \~ 1:40,000 \[[@CR2]\], and it only accounts for 5--10% of all cases of MEN2 \[[@CR3]\]; MEN2B was officially named by Chongaverage age of diagnosis of MEN2B is 14.2 years \[[@CR8]\]. In this case, the patient had got intractable constipation since early infancy. She was not diagnosed until a neck mass was found. However, lymph node metastasis and thymus metastasis occurred when MTC was diagnosed, and the best surgical opportunity had been missed. It has been suggested that *RET* gene sequencing should be performed to rule out MEN2B when HD is considered \[[@CR11]\]. The curative rate of early thyroidectomy for MTC without metastasis can reach as high as 100%. Since the prevalence of MTC is 100% in patients with the p.M918T mutation of the *RET* gene, the current guidelines of the American Thyroid Association (ATA) recommend that if children have this mutation, thyroidectomy be performed before the patients reach 1


companion bill, SB 460, remains under consideration by the NC Senate, and it still contains the provision that would essentially nullify existing lawsuits. North Carolina Environmental Justice Network’s Muhammad says it’s anyone’s guess whether the legislation will make into law. After all, this is a state that recently repealed one odious “bathroom bill” under pressure, only to replace it with “new legislation that LGBT rights advocates say is just as bad,” as Mother Jones’ Ashley Dejean recently reported. “We’re in a fix here in North Carolina,” Muhammad told me. “It’s just one bad thing [coming from the legislature] after another.”31)
        date = datetime.datetime(2016, 3, 3)
        trans_dt = ck_utils.add_month(base_date, False)
        self.assertEqual(date, trans_dt)

    def test_add_month_keep_leap(self):
        base_date = datetime.datetime(2016, 1, 31)
        date = datetime.datetime(2016, 2, 29)
        trans_dt = ck_utils.add_month(base_date)
        self.assertEqual(date, trans_dt)

    def test_sub_month_leap(self):
        base_date = datetime.datetime(2016, 3, 31)
        date = datetime.datetime(2016, 3, 3)
        trans_dt = ck_utils.sub_month(base_date, False)


   def test_convert_fraction(self):
        result = ck_utils.num2decimal(fractions.Fraction(1, 2))
        self.assertEqual(result, decimal.Decimal(1.0 / 2))

    def test_convert_float(self):
        result = ck_utils.num2decimal(0.5)
        self.assertEqual(result, decimal.Decimal(0.5))

    def test_convert_int(self):
        result = ck_utils.num2decimal(2)
        self.assertEqual(result, decimal.Decimal(2))

    def test_convert_decimal(self):
        result = ck_utils.num2decimal(decimal.Decimal(2))
        self.assertEqual(result, decimal.Decimal(2))
the Sea Parish, and the Ocean City Volunteer Fire Company Engine 703. From 2002 to 2006 Jim represented the Coastal Bays Watershed, Ocean City and Worcester County, on the State of Maryland Critical Area Commission.  In 2004 he served as State Chairman for WalkAmerica for the March of Dimes. Jim was the President of the Lower Eastern Shore Mayors Association in 2004 and was the Honored Chairperson for the Light the Night Walk and The Leukemia & Lymphoma Society in 2004.

Political career
Mathias began his political career in Ocean City in 1987 when he was appointed to the Ocean City Board of Zoning Appeals, where he served until 1990. In October 1990, he was elected as an Ocean City Councilman and was re-elected to that post in 1994.


likely to generalize to others in the population. Single-subject researchers also note that they place a strong emphasis on replicating their research results. When they observe an effect with a small sample of participants, they typically try to replicate it with another small sample—perhaps with a slightly different type of participant or under slightly different conditions. Each time they observe similar results, they rightfully become more confident in the generality of those results. Single-subject researchers can also point to the fact that the principles of classical and operant conditioning—most of which were discovered using the single-subject approach—have been successfully generalized across an incredibly wide range of species and situations.

And again turning the tables, single-subject researchers have concerns of their own about the external validity of group research. Oneextremely important point they make is that studying large groups of participants does not entirely solve the problem of generalizing to other individuals. Imagine, for example, a treatment that has been shown to have a small positive effect on average in a large group study. It is likely that although many participants exhibited a small positive effect, others exhibited a large positive effect, and still others exhibited a small negative effect. When it comes to applying this treatment to another large group, we can be fairly sure that it will have a small effect on average. But when it comes to applying this treatment to another individual, we cannot be sure whether it will have a small, a large, or even a negative effect. Another point that single-subject


story of survival to be more emphasized.

I would love to see more movies about colonial troops- they could tell a really good, true story about their contributions to the war effort, overcoming distrust or racism to perform valiantly, etc. etc. How awesome would a movie about Guhkras be?

There is no need for forced diversity in a movie- the experience of WW2 was so immense, filmmakers could make movies SOLELY out of the stories of white men for hundreds of years, and still not tell everything. There are so many stories to tell, each can, and should get their own.

Does that mean multiple stories cannot be told at once? Of course not. But complaining about a movie solely because it has too many white people, and isnt delivering adown, that overseas players are soft. It’s somehow part of the English football DNA.

Overseas tarts will rarely compare with our own terriers. The received wisdom is that before the foreign legion turned up there was no shirt-pulling, no waving of imaginary cards, no diving. Just a solid man’s game. A 100-percenter like Billy Bremner is still more likely to win the genuine affection of a British crowd that a “softy” like Ronaldo, no matter how talented he might be.

However much we talk about improving our game. However much we spend on doing so, that love of the physical can never be entirely eradicated, even when we see our own clubs outclassed by the Madrids, Barcelonas and Bayerns. We hold fast to the philosophy that a good big ’un


The Twilight of the Empire Age: Whose World Will It Be?

By: Amir NOUR for the Saker Blog

“We can bomb the world to pieces, but we can’t bomb it into peace”

(Michael Franti)

David and Goliath in an upside-down world

President Donald Trump doesn’t seem to share Georges Clemenceau’s view that “war is too serious a matter to be left to the military”. All the more so, perhaps, since the French statesman is also said to have coined the acerbic comment “America is the only nation in history which miraculously has gone directly from barbarism to decadence without the usual interval of civilization”.

Indeed, shortly after his inauguration as the 45th President of the United States, in January 2017, the American President bestowed additional authority upon the Pentagon and the CIA. In soa combination of borrowed money and disinvestment in domestic physical and human infrastructure. The result is not just the imposition of a crushing burden of debt on our posterity, but lost growth and declining U.S. economic competitiveness”. Furthermore, he lamented, Americans have become accustomed to life under surveillance and in an endless state of apprehension about acts of terrorism. Such an unusual condition has predictably eroded their liberties, aggrandized the presidency, reinforced “cowardly herd instincts in Congress”, and helped to impoverish the US middle-class “while enriching the military-industrial complex”. These, he concluded, are “structural alterations to the American republic and way of life that will affect both for decades”.

According to Philip Alston, the United Nations Special Rapporteur on extreme poverty and human rights, “the American Dream is rapidly


of the adoption of the Declaration of Independence. They issued a Platform in which they reaffirmed their faith in the “immortal proclamation of the inalienable rights of man” and their “allegiance to the Constitution framed in harmony therewith by the fathers of the Republic”. Among other principles reiterated: “We declare again that all governments instituted among men derive their just powers from the consent of the governed” and “that to impose upon any people a government of force is to substitute the methods of imperialism for those of a republic” ; “We are in favor of extending the Republic’s influence among the nations, but we believe that that influence should be extended not by force and violence, but through the persuasive power of a high and honorable example”“in disarray” which the U.S. is unable to shape in its image and interests. Haas thinks that the U.S. remains the greatest country in such a world, but its foreign policy has at times made matters worse—both by what America has done and by what is has failed to do.

A similar advice, or rather warning, has been given by no other powerful American conservative voice than Robert Kagan. In a Brookings article, he affirmed that “the liberal world order established in the aftermath of World War II may be coming to an end, challenged by forces both without and within”. He concluded by saying that “if the next president governs as he ran, which is to say if he pursues a course designed to secure only America’s narrow


interests; focuses chiefly on international terrorism—the least of the challenges to the present world order (…) then the collapse of the world order, with all that entails, may not be far off”.

Most significantly, in June 2017, a Pentagon study was released and caused rivers of ink to flow, both in the U.S. and overseas. It is worth noting that the commissioning and preparation of this report began in June 2016, six months before the end of the Obama administration, and was completed in April 2017, four months into the Trump administration. It required and involved extensive consultations with officials across the Pentagon and a handful of American think-tanks of a somewhat neoconservative persuasion.

Among the report’s most stunning conclusions are : “the status quo that was hatched and nurturedtheir radical hybridity. The more insistent we are on the separation of the cultures, the more inaccurate we are about ourselves and about others. The notion of an exclusionary civilization is to my way of thinking an impossible one”. Prof. Said then asked what he considered as the “real question”, that is “whether in the end we want to work for civilizations that are separate or whether we should be taking the more integrative but perhaps more difficult path which is to try to see them as making one vast whole, whose exact contours are impossible for any person to grasp, but whose certain existence we can intuit and feel and study”. He concluded his lecture by quoting some lines by the great poet, author and politician from


was the main reason we picked Neo over him.

Right after NEO’s addition you had a bootcamp in Esports Performance Center in Warsaw. How do you rate this facility? Could you somehow compare it with other places of this type?

I think the facility is one of the best we’ve been at, although we booked a hotel nearby since the rooms at the bootcamp don’t have a toilet but the pracc rooms, PC’s, internet, everything was good. Special shoutout to the chef for making some great food for us! We were hoping of going there before the Major but they already gave the room to another team.

In terms of communication – is NEO already capable of in game leading in English on his highest level? If not, what are theHe is bringing over some more structure and attention to detail so we’ve just been slowly trying to implement some new things while also bringing him up to speed with some of the stuff we’ve already been doing which have been working pretty well for us.

Obviously cooperation between coach and IGL is crucial for every team. How does it look like in your case?

It’s going great, at least from my side of things, Filip is super easy to work with and we have a lot of productive talks about the team, the things we need to work on etc. I’m hoping for more frequent bootcamps since you can be much more productive than with online practice, so I’m looking forward to the preparation we will do before the


let teams get a free veto if they don’t really play Vertigo just because the map is new so yeah, you can expect it to be a big part of our veto here in Cologne as well.

Your first opponent in Germany is Renegades. Are you specially preparing for this game or are you going to just focus on yourselves?

We’ll just focus on ourselves and creating a solid gameplan, so everyone is on the same page, they’ve had a bootcamp before this tournament, so it’s fair to expect them having new things prepared for our game.

Do you believe that in Cologne your team will be able to threaten Liquid or Astralis or are you already preparing your peak form for the Major? After all you changed your IGL not    g_movecs_mo_gs(1))
      ok=ok.and.ga_create(mt_dbl,m,m,"movecs_gs b", 0,0,
     $     g_movecs_mo_gs(2))

C     (Fock mats at previous times (for Magnus) in MO basis)
      ok=ok.and.ga_create(mt_dcpl,m,m,"F'a(t-1/2*dt)",
     $     0,0, g_zfock_mo_n12dt(1))
      ok=ok.and.ga_create(mt_dcpl,m,m,"F'b(t-1/2*dt)",
     $     0,0, g_zfock_mo_n12dt(2))

C     (static Fock matrix)
      if (params%static) then
         ok=ok.and.ga_create(mt_dcpl,n,n,"F(t=0) alpha",
     $        0,0, g_zfock_ao_init(1))
         ok=ok.and.ga_create(mt_dcpl,n,n,"F(t=0) beta",


  $        0,0, g_zfock_ao_init(2))
      endif

      if (.not.ok) call errquit(pname//"GA allocation failed", 0,GA_ERR)

      if (.not.ma_push_get(MT_Dbl,m,'moocc alpha',lmoocc(1),imoocc(1)))
     &     call errquit(pname//'cannot allocate moocc(1)',0, MA_ERR)

      if (.not.ma_push_get(MT_Dbl,m,'moocc alpha',lmoocc(2),imoocc(2)))
     &     call errquit(pname//'cannot allocate moocc(2)',0, MA_ERR)

      do is = 1, nspin
         call ga_zero (g_zdens_ao(is))
         call ga_zero (g_zdens_mo(is))
         call ga_zero (g_zfock_ao(is))
     tt = params%tmin + (it-1)*params%dt
         tt = tt + params%dt

         if (params%prof) call prof_end (elapsed, "Complete time step")

      enddo

C
C     I suppose technically we should print the time-dependent system
C     properties here, as we have yet to that for the current (advanced)
C     time.  We're only losing one value (the last time) so it's not a
C     big deal, though....
C

C     (NOTE: uses it, tt values *outside* loop but not important)
      call rt_tddft_print_msg (params, tt, "Propagation finished")

C


    == Cleanup GAs for time-dependent quantities and params ==
      ok = .true.

      do is = 1, nspin
         ok = ok .and. ga_destroy(g_zdens_ao(is))
         ok = ok .and. ga_destroy(g_zfock_ao(is))
         ok = ok .and. ga_destroy(g_zdens_mo(is))
         ok = ok .and. ga_destroy(g_zfock_mo(is))
         ok = ok .and. ga_destroy(g_zfock_mo_n12dt(is))
         ok = ok .and. ga_destroy(g_densre_ao(is))
         ok = ok .and. ga_destroy(g_densim_ao(is))
      successfully sought a warrant authorizing a search of the
package and seizure of, among other items, proceeds of drug trafficking.

   When officers opened the box, they found U.S. currency wrapped in
multiple layers of sealed packaging. After a canine alerted that the money
itself—not just the packaging—contained the odor of narcotics, officers
seized the cash and obtained a court order to turn it over to federal
authorities.

   Michael Hodges, the person who shipped the parcel, argues that the
seizure was unlawful because it exceeded the warrant’s scope—making
the turnover of the cash improper. We disagree. The totality of the
circumstances established the necessary probable cause to believe the
money was proceeds of drug trafficking.

   Because the seizure was lawful, we affirm the turnover order.

Facts and Procedural History
   In October


 Multiple statutes govern the turnover of property from state to federal
authorities. First, Indiana Code section 34-24-1-1 permits seizure of
property, including money, that meets certain criteria. Next, under Section
35-33-5-5(j), a prosecuting attorney may move to transfer the seized
property to federal authorities, and the reviewing court “shall order”
turnover of the property (if it was properly seized) for disposition under
federal statutes and regulations.

   Hodges does not dispute that probable cause supported the warrant to
search the package. He argues only that the seizure exceeded the
warrant’s scope and was thus unlawful.

   The State disagrees, maintaining that the totality of the circumstances
established the necessary probable cause to seize the cash.

   We agree with the State: the seizure was properly supported by
probable cause to believe the cash wasthe circumstances requires
courts to consider “the whole picture,” which is often greater than the
sum of its parts (first quoting Gates, 462 U.S. at 234; then quoting United
States v. Cortez, 449 U.S. 411, 417 (1981))).

   When reviewing for probable cause, we do not focus on post hoc
explanations for the circumstances. See McGrath, 95 N.E.3d at 528. Rather,
we assess “the degree of suspicion that attaches to particular types of
noncriminal acts.” Gates, 462 U.S. at 243 n.13; see McGrath, 95 N.E.3d at
528. And we view the circumstances from the standpoint of an objectively
reasonable police officer, Pringle, 540 U.S. at 371 (quoting Ornelas v. United
States, 517 U.S. 690, 696 (1996)); McGrath, 95 N.E.3d at 529, keeping in
mind that both inferences based on the officer’s own experience and
“common-sense conclusions about human


periphery of the pedestal area they inspected. There may have been enough distance and paths for heat to radiate out that these areas didn’t fail completely.

Measurements in above graphic are in feet.

Materials found on the remaining grating appeared to be a mix of black and brown corium (melted fuel mixed with other materials). TEPCO claimed it might be burned paint yet the substances appeared to look more like splatters of corium in the locations closer to the center of the pedestal.

The information TEPCO did release did not include any inspection further into the center of the pedestal where the most damage may have taken place. We did obtain some additional photos from the video. These provided more views but not much additional information, those images are included belowpedestal opening appears clouded with steam or interference. A white splatter can be seen along the pedestal wall.

TIPS probe pipes can be seen in this image. These pipes appear to be mostly intact.

This “flat bar” section is closer to the pedestal wall yet shows what appears to be possibly brown corium on the surface.

The CRD platform appears to have the same residues.This section of pedestal grate appears worse than others, showing a slumped appearance in parts and the same thick residues.

Below are some of the additional images we obtained from the video.
What happens next appears to fall into IRID & Toshiba’s court. With this information in hand they will need to determine if the robot can travel along the pedestal grate in the current conditions. The robot is


equipped with a water jet capable of blasting some debris out of the way. It is not clear if it would be able to dislodge chunks of corium that may be fused to the grate. If it is capable of breaking off these chunks the remaining grate may be extremely uneven or with holes. So far test runs of the robot have been conducted on intact grating materials.

This article would not be possible without the extensive efforts of the SimplyInfo research team
Join the conversation at chat.simplyinfo.orgconducted by Locker et al., Hassel et al., Ikebe et al., and Osta et al. also showed that the GOHAI was more successful in detecting elderly people's oral health problems \[[@B13],[@B17]-[@B19]\]. However, having regard to the fact that the OHIP-14 encompasses a longer time interval than the GOHAI, the opposite proportion might be expected. According to Lockers et al. \[[@B13]\], the GOHAI gives a greater weight to the more immediate outcomes like functional limitations and pain and discomfort, and therefore more common outcomes of oral disorders compared to the OHIP-14 which focuses on more severe and less common, like psychological and behavioral outcomes. In our study the GOHAI showed an impairment that was not reflected by the OHIP-14. Consequently, the studies that assessed only one measure, either the


terms of developer work.
And easy to read, at least for people familiar with regex.

A:

Your current solution could be more optimal if you

Pre-allocated StringBuilder's capacity, which is possible in your case because the result string is at most the same length as the input string:
StringBuilder sb = new StringBuilder(s.Length);

Avoided constructing a char array to iterate through. The string class implements IEnumerable<char> so you might fed it directly to foreach:
foreach (var item in s)

A:

Race your horses!
Here is a pointer version using fixed and unsafe with pre-allocated result
unsafe string Mine()
{
   var temp = string.Copy(Input);
   var i = 0;
   fixed (char* pInput = Input, pTemp = temp)
   {
      var plen = pInput + Input.Length;
     know the whole thing is rather curious to me.”

Tambor is one of many stars affected this past year in Hollywood. The Time’s Up movement was also present at Sunday’s Oscars. Watch the clip below to see how women are speaking out.


Schistosomicidal activities of Lymnaea stagnalis haemocytes: the role of oxygen radicals.
Macrophage-like defence cells (haemocytes) of the pond snail Lymnaea stagnalis mediate cytotoxicity through reactive oxygen intermediates (ROIs). This activity is NADPH-oxidase dependent, as in mammalian phagocytes during the respiratory burst. In this study, mother sporocysts of schistosomes, the compatible Trichobilharzia ocellata and the incompatible Schistosoma mansoni evoke in vitro ROI activities (detected by luminol dependent chemiluminescence, LDCL) from L. stagnalis haemocytes. S. mansoni is encapsulated by haemocytes and eliminated, whereas T. ocellata escapes encapsulation and survives. Both schistosomes were equally susceptible to in vitro oxidative damage from exposure to hydrogen peroxide and to ROIs generated by a xanthine/xanthine oxidase system. Protocatechuic acid, a specific antagonist of NADPH-oxidase, delayed the killing of T. ocellata and S. mansoni sporocysts byyears by that time. The State questioned
     Officer Ruggiero as to his familiarity with the area:
                 “Q. And were you in the vicinity of 634 Ridgeway in Chicago?
                 A. Yes.
                 Q. Is that area within the 11th District?
                 A. Yes.
                 Q. Can you please


describe the six hundred block of North Ridgeway for the jurors?
                 A. Yes. The area is residential, with buildings and also right next to a school called
             Ryerson Elementary School at that time.
                 Q. You say at that time. Does that school have a different name?
                 A. Yes.
                 Q. What is that?
    He disputes, however, that the State presented sufficient evidence to prove him guilty of the
       enhancement provision, which elevates the penalty where an underlying offense occurs within
       1000 feet of the real property comprising a school. See 720 ILCS 570/407(b)(1) (West 2012).
¶ 15       Second, Hardman contends that, because the trial court imposed a public defender fee
       without first inquiring into his financial circumstances, in accordance with the requirements of
       section 113-3.1(a) of the Code of Criminal Procedure of 1963, “no hearing” took place. Thus,
       according to Hardman, the


a controlled substance is a Class X felony when committed within 1000 feet of the
       real property comprising any “school.” 720 ILCS 570/407(b)(1) (West 2012). Hardman
       acknowledges that the State proved he possessed a controlled substance with intent to deliver.
       See 720 ILCS 570/401(c)(1) (West 2012). However, for purposes of proving the locality
       enhancement under section 407(b)(1), Hardman disputes that the evidence presented at trial
       established that the building at issue was a school.
¶ 18       To establish that an offense occurred within 1000 feet of a school, Hardman asserts that the
 the definition of “school” contained within the Criminal Code of 2012 (Criminal Code), which
       provides that a school “means a public, private, or parochial elementary or secondary school,

                                                    -5-
       community college, college, or university and includes the grounds of a school.” 720 ILCS
       5/2-19.5 (West 2012).
¶ 21       Hardman contends that this court’s decision


in Young, 2011 IL 111886, requires
       particularized evidence of the location’s use to prove the enhancing location element. In
       Young, this court considered whether the term “school” contained in section 407(b)(2) (720
       ILCS 570/407(b)(2) (West 2008)) encompassed preschools. Young, 2011 IL 111886, ¶ 1.
       There, the defendant challenged whether the State had provided sufficient evidence to prove
       that the offense occurred within 1000 feet of a school. Id. At trial, there was testimony that the
       offense occurred within 1000 feet of the “ ‘High Mountain Church and Preschool,’ ” but no
 court noted that “[t]he officers did not testify that they lived in the area or
       that they regularly patrolled the neighborhood, so as to allow an inference that they had

                                                   -7-
       personal knowledge as to whether the school was in operation on the date of the offense.” Id.
       The Boykin court also commented that “there was even less evidence presented


    fact could have found the essential elements of the offense beyond a reasonable doubt.” People
       v. Baskerville, 2012 IL 111056, ¶ 31. All reasonable inferences from the evidence must be
       drawn in favor of the prosecution. People v. Martin, 2011 IL 109102, ¶ 15. “This standard of
       review does not allow the reviewing court to substitute its judgment for that of the fact finder
       on questions involving the weight of the evidence or the credibility of the witnesses.” People v.
       Jackson, 232 Ill. 2d 246, 280-81 (2009). “[I]n weighing evidence, the trier of factwas named Ryerson on the date of the offense. Officer Harmon also
       testified that the name of the school had changed to Laura Ward.
¶ 42       Hardman maintains that, “[a]t best, the State’s evidence showed that the building was
       undergoing changes that summer, as indicated by the different names.” We reject this
       argument. A rational trier of fact could have found that Ryerson Elementary became Laura
       Ward Elementary. A change in school name, alone, does not mean that 646 North Lawndale
       Avenue stopped being a school during the transition.
¶ 43


Accordingly, the Illinois legislature enacted section 113-3.1 to
       remedy the due process violation identified in Cook by requiring that a trial court conduct a
       hearing that considers the defendant’s financial ability to pay the fee before the fee may be
       ordered. Love, 177 Ill. 2d at 559. The hearing must occur within 90 days of the entry of the
       final order disposing of the case. 725 ILCS 5/113-3.1(a) (West 2012).
¶ 48       Hardman asserts that the circuit court violated his due process rights when it failed to notify
       him that it was considering      court did not need to reach the issue of whether the 90-day time limit is mandatory or directory.
       Id.
¶ 59       We agreed that the few questions posed by the trial court to defendant regarding his
       employment status were insufficient to satisfy section 113-3.1(a). Id. ¶ 14. We made clear
       what is required for a proper hearing pursuant to section 113-3.1(a) and then concluded that a
       hearing, albeit an insufficient one, had occurred:
                “To comply with the statute,


  observed that the trial court had asked defendant about his ability to obtain a job, whether
       defendant would use future income to pay for his fines and costs, and if there was a physical
       reason why defendant may not be able to work. Id. As one panel reasoned, if “some sort of a
       hearing” means only a hearing in the ordinary or abstract sense, it would have been pointless
       for this court to focus on the trial court’s three questions about the defendant’s finances.
       Castillo, 2016 IL App (2d) 140529, ¶ 13. For example, “[h]ad thecase went to
       trial, and then imposed a fee of $500. Among other deficiencies, the trial court did not consider
       Hardman’s financial circumstances and did not obtain a financial affidavit. See 725 ILCS
       5/113-3.1(a) (West 2012). We need only determine whether “some sort of a hearing” occurred
       and, in turn, the proper remedy.
¶ 66        Despite the deficiencies attendant to the trial court’s imposition of the fee, we remand the
       cause for a proper hearing because “some sort of a hearing” occurred. Under Somers, “some
       sort


score these parts using my Scor-pal. The top panel was printed but could have been stamped just as well but I did the quickest way. I used Sizzix die to cut Snowflakes from Silver Metallic CS to finish.

I used dollars bills for the photo but plan to fill with larger denominations.

Challenges:Scor-Pal Challenge: Monthly challenge is anything goes with your Scor-Pal using more than one score. The boxes and covers were scored with several scores.

Hello! I have been away from my blog the last few days. The holidays seemed to have arrived so quickly this year....tonight begins Hanukkah with a dinner of Prime Rib and Potato Latkes or maybe Potato Kugel. I have not wrapped one gift as yet so I must get busy.

I made these gift tags aPaper from Timbergrove pad. Added sentiment stamped in SU Sage Shadow ink cut with more of the Labels dies and Snowflakes cut with Sizzix die from Glossy White CS. The ribbon at lower edge of card is American Crafts.

Friday, December 5, 2014

Welcome to my studio. Today I have a Christmas card that I made with a Silhouette File and Cheery Lynn Dies. The Nativity scene was cut with the Cameo from Black CS and the Sentiment was cut with the dies. I simply attached both to pattern paper from American Crafts Kringle & Co pad and then a White CS base.

Wednesday, December 3, 2014

Hello! Today I have some Christmas tags. This one is made with Heartfelt Creations Stamp that I colored with Memento Markers and Copics. I cut


a body with White CS and placed him on a rectangle of Red CS and then onto a Tag cut from Kraft CS and embossed with Darice EF Snowflakes. I finished with Black gems for buttons.

Challenges:The Card Concept: Challenge 1.) Make A TAG or a CARD with a tag on it. 2.) Use a Snowmen, snow or any other "wintery" theme!The Kraft Journal : Challenge #200 Christmas Gift Tags

Now to do some shopping for presents for the tag.I enjoy all your comments. Thank you.
Theresa

Monday, December 1, 2014

Welcome to my studio. Today I have a very quick and simple card....a CAS one. This will fit several challenges. On the card base of Bazzill blue CS, I attached a mat of lustrous Oyster Pearl CS and topped that with aQ:

Count number of cells in a range that match the content of a different cell

I am trying to use COUNTIF in Excel to find how many items in a range match the contents of a separate cell. The idea is, the range contains everyone's answers to a given question (a one-word, non-numeric answer); the comparison column contains the correct answer. I want a count of how many people got the answer correct.
I tried: =COUNTIF(C16:BT16,"=BU16")
But it appears COUNTIF won't let me reference a cell with the criteria in it -- it requires the match criteria directly in the formula, such as =COUNTIF(C16:BT16,"DEN"). I can do that, of course, but I'd have to edit dozens of formulas every time I evaluate answers, and it would be much less timeconsuming


type liquid crystal display device colors light by utilizing the birefringent action of a liquid crystal layer of the liquid crystal cell and the polarization action of at least one polarizing plate. Since it is free of absorption of light that takes place when color filters are used, it can perform bright color display at high light transmittace.
Moreover, the ECB type liquid crystal display device varies in birefringence of the liquid crystal layer depending on the state of alignment of liquid crystal molecules in accordance with the voltage applied across the electrodes of both the substrates of the liquid crystal cell. Following such variations, the polarization state is varied with each wavelength light entering the other polarizing plate, so that the color of colored light can be changedfollowing illustrates only three forms of academic dishonesty:

Plagiarism, e.g. the submission of work that is not one’s own or for which other credit has been obtained.

Improper collaboration in group work.

Copying or using unauthorized aids in tests and examinations.

Email correspondence policy

It is the policy of the Faculty of Humanities that all email communication sent from students to instructors (including TAs), and from students to staff, must originate from each student’s own McMaster University email account. This policy protects confidentiality and confirms the identity of the student. Instructors will delete emails that do not originate from a McMaster email account.

Modification of course outlines

The University reserves the right to change dates and/or deadlines etc. for any or all courses in the case of an emergency situation or labour disruption or civil


Arduino-driven motor control board, uses
the Go programming language, and produces beautifully detailed
drawings on the fly.

InMoov[8]: The
first open source, 3D printed, life-size robot that can be
replicated on any home 3D printer with a 12cm area. InMoov was
conceived as a development platform for all Makers.

Light Play[9]: An
interactive hive of miniature delta robots made from 3D printed
parts, which act as a mechanical prosthetic for enhancing
self-expression.

Project Daffodil[10]: An
electronic pop-up book featuring princess engineers and electrical
dragons that's embedded with simple circuits, introducing young
girls to the world of engineering and teaching the basics of
circuitry.

Rhino Redemption[11]:
Created by Reared in Steel, Rhino Redemption is a fire-breathing
rhinoceros art car that stands 11 feet tall by almost 10 feet wide
and is 28 feet long. It's fully equipped with hydraulic steering, a
sound system, and LED lights.

Robot Resurrection[12]: A
towering 28-footcakes, casseroles, tapioca pudding, flan, flour, and even beverages, among other dishes.

Tapioca flour, tapioca noodles, and tapioca pearls are all made from the powdered yuca root.

Those who must consume a gluten-free diet can benefit immensely from its flour.

As long as you peel your yuca thoroughly, yuca is safe to eat. However, it is important to know that it does contain a natural poison in the skin. The yuca root should not be eaten raw (not that you would want to) it has to be cooked properly to detoxify it. After peeling and normal cooking, it is safe to eat.

What are the Health Benefits of Yuca?

Its roots are very rich in nutrients, which then makes it a deal breaker for those who are new to this component.

As for the


most favorable to Caribbean, drawing all reasonable inferences in its favor. Gray v. Evercore Restructuring L.L.C., 544 F.3d 320, 324 (1st Cir.2008).
Brown Forman is a corporation organized under the laws of the State of Kentucky. Brown Forman markets and distributes Finlandia vodka and Jack Daniel's whiskey in the United States and Puerto Rico. Caribbean is a corporation organized under the laws of the Commonwealth of Puerto Rico. As the complaint avers, in 1996, Caribbean entered into a series of oral agreements with Primalco Ltd., Brown Forman's predecessor, by which Caribbean agreed to promote Finlandia in Puerto Rico. In August 2002, Brown Forman and Caribbean formalized this commercial relationship in a written "promotion agreement," whereby Caribbean agreed to employ its best efforts to promote Finlandia vodka in Puerto Ricoface of the repeal of Puerto Rico's parol evidence rule.[9] However, we need not conclusively decide this issue that involves Puerto Rico's rules of contract interpretation. Even if we consider evidence tending to show that the parties intended to omit Caribbean's sales duties from the promotional agreements, the evidence is insufficient to establish that Caribbean procured and closed sales on Brown Forman's behalf in an exclusive manner as required by Law 21.
First, Caribbean's well-pleaded allegations regarding its sales activities do not support the conclusion that Caribbean had the authority to procure and conclude sales on Brown Forman's behalf. Per Caribbean's allegations and admissions, Caribbean procured and sent purchase orders to the local distributors who then processed and concluded the sales. Caribbean also admitted that it did not place


breach of the implied covenant of good faith and fair dealing. The district court dismissed this claim, finding that the arbitration clauses included in each of the promotional agreements required the parties to arbitrate the claim.[10] In relevant part, the arbitration clauses included in the promotional agreements stated that "[a]ny controversy or claim arising out of or relating to this Agreement or the breach thereof shall be finally settled by arbitration in Louisville, Kentucky administered by the American Arbitration Association...."
On appeal, Caribbean claims that its breach of contract claim is not subject to arbitration because it arises out of the terms of the oral sales representation agreements. Viewing the oral sales representation *450 contracts as separate and independent agreements, Caribbean contends that the arbitration clauses included in thethat the district court did not commit plain error in its award of attorneys' fees to Brown Forman and, therefore, affirm on this issue.
First, although the district court failed to make an express determination as to Caribbean's obstinance or frivolousness, we find that such determination is sufficiently implicit and supportable on the record to withstand plain error review. For example, in its opinion and order dated November 8, 2007, the district court correctly noted that Caribbean "[c]learly" *453 did not meet the exclusivity requirement of Law 21, and found Caribbean's "assertion that the alleged sales representation agreements provided for the same payment terms as the promotional agreements to be preposterous." IOM Corp. v. Brown-Forman Corp., 553 F.Supp.2d 58, 64-65 (D.P.R.2007) (emphasis added). Also, the record shows that Caribbean


has put forth inconsistent arguments regarding the scope of the agreements.[14]
Caribbean argues that its actions cannot be considered obstinate or frivolous in light of the fact that, at the time it filed the complaint, the Puerto Rico Supreme Court had yet to interpret Law 21. This factor, however, is not sufficient to conclude that the district court committed plain error. Pérez Marrero v. Colegio de Cirujanos Dentistas de Puerto Rico, 1992 P.R.-Eng. 754,861, 131 D.P.R. 545 (1992) ("The fact that the issue is `new,' ... does not give a party a `carte blanche' to act in an obstinate or frivolous manner." (emphasis omitted)). As previously explained, Caribbean presented various inconsistent arguments and its well-pleaded facts failed to establish a number of the elements clearly required for a LawForman. See Appellee's Supplemental Appendix at 52-66.
[6]  Caribbean claims that two letters dated March 24, 2006 and April 5, 2007, reveal that Brown Forman treated the company's agreements with Caribbean as "broker agreements," rather than "promotional agreements."
[7]  Law 448 of September 23, 2004 repealed Puerto Rico's parol evidence rule, which previously stated:

When in an oral or written agreement, either public or private, all the terms and conditions constituting the true and final intention of the parties have been included, such agreement shall be deemed as complete, and therefore, there can be between the parties, or successors in interest, no evidence extrinsic to the contents of the same, except in the following cases:
(1) Where a mistake or imperfection of the agreement is put in issue by the


Wednesday, July 2, 2008

I recall with great fanfare the buttons and messaging - "80 is the new 20" that was heralded from the booth of Digital Railroad during last year's PhotoPlus Expo (PhotoPlus Expo Day 2 - Highlights, 10/20/07). What exactly does that mean, I wondered.

The explanation was quite simple, actually. Major agencies were collecting, say, $100 for an image license, and paying the photographer $20, or, a 20% commission. Conversely, Digital Railroad instituted just the opposite approach - paying photographers 80% of the sale, and keeping 20%. To me, that made perfect sense.

Until now.

(Continued after the Jump)

Before I get into that, let me go back a bit. Back in the days of film, it was common for there to be a 50/50 split, and it was justifiedor less?

Then they wrote:

if you've recently renewed your subscription and it's not set to expire for several months, please note that we will respect your current agreement until your next renewal date. All new pricing and fees will then apply upon renewal.

Does this mean that you won't get that extra 80GB for the additional $0.05/mo unless you also agree to a 10% per sale reduction? Hmmm.

Back in January, we wrote about staffing cuts (Digital Railroad makes major layoffs, 1/10/08), which ended up being about 50% of the total number of people working for them, both on staff, and contractors, and in November I wrote about a major leadership change (Stepping Down, or Stepping Up? DRR's Nisselson Makes A Change, 11/21/07), which, from all appearances, ended up being the


Alpine Touring boots allow us to meet Mother Nature on her terms, to rise to the never-ending challenges in the snowy peaks, or simply to lay fresh tracks in a familiar backcountry bowl. Crafted for performance, comfort and efficiency, SCARPA's AT boots celebrate the pursuit of adventure.a floppy drive. I'm afraid the Windows 98 floppy won't be of much help here (there is probably some clever way to boot a live CD from MS-DOS, but it won't be as easy as just trying SBM).


Patient Advocacy Organizations, Industry Funding, and Conflicts of Interest.
Patient advocacy organizations (PAOs) are influential health care stakeholders that provide direct counseling and education for patients, engage in policy advocacy, and shape research agendas. Many PAOs report having financial relationships with for-profit industry, yet little is known about the nature of these relationships. To describe the nature of industry funding and partnerships between PAOs and for-profit companies in the United States. A survey was conducted from September 1, 2013, to June 30, 2014, of a nationally representative random sample of 439 PAO leaders, representing 5.6% of 7865 PAOs identified in the United States. Survey questions addressed the nature of their activities, their financial relationships with industry, and the perceived effectiveness of their conflict of interest policies. Amount and sourcesleft behind. You had a good day? All right, man, y'all be good. Reporter: Now, 15 years after trap music first came out, tip is releasing his ninth studio album "Dime trap" which is out right now. This is two chains exhibit. He donated this car to us, let us use it. Reporter: In his old neighborhood he's opened up a popup trap museum, homage to the genre. Over here, this is Gucci man's exhibit. An actual crack house, if you will. Looks like there's weed, not crack. Well, actually -- Oh, it's both. Crack there. At least simulated. This is not real crack? This is not real crack. How do you draw the line between celebrating/glorifying, or just documenting? This is what the deal. These are the


crime of violence, in violation of 18 U.S.C. §§ 2 and 924(c), as well as a street-

gang enhancement, 18 U.S.C. § 521. At the four-day jury trial, the Government focused on

establishing Tibbs’s involvement in the planning of the robbery, relying mainly on the testimony

of the other Vice Lords. The Government cast the robbery as a gang initiation orchestrated by

Tibbs to finance the gang. The Vice Lords witnesses testified that, among other things, Tibbs

told the crew that they would need weapons, face masks, and gloves; that they would need to do

something about the cameras; and that they should make sure to leave no evidence.

       The jury returned a verdict of guilty on both counts, and additionally found that Tibbs

had aided and abetted brandishing                     -9-
No. 15-1060, United States v. Tibbs

M.C.L. § 333.7401 provide alternative means rather than elements. Second, Hinkle addressed

only the word “deliver” and its definition; it did not discuss the full text of the predicate-offense

statute, which states that a person commits the offense “if the person knowingly manufactures,

delivers, or possesses with intent to deliver a controlled substance listed” in the penalty group.

832 F.3d at 572. Hinkle held only that the element of delivery was indivisible, and did not

address whether the entire statute was indivisible such that manufacture, delivery, and possession

with intent to deliver stated alternative means of satisfying a single element. Id. at 576. The

latter, unaddressed inquiry is at


for the

conviction” by examining a limited class of trial-court materials. Johnson v. United States,

559 U.S. 133, 144 (2010).

        The Hobbs Act provides:

                Whoever in any way or degree obstructs, delays, or affects commerce or
        the movement of any article or commodity in commerce, by robbery or extortion
        or attempts or conspires so to do, or commits or threatens physical violence to any
        person or property in furtherance of a plan or purpose to do anything in violation
        ofcrime of violence, we held in United States v. Taylor, 176 F.3d 331 (6th

Cir. 1999), that conspiracy to commit Hobbs Act robbery is a crime of violence under

§ 924(c)(3)’s residual clause. Id. at 337–38; see also, e.g., United States v. Elder, 88 F.3d 127,

129 (2d Cir. 1996) (per curiam); Mendez, 992 F.2d at 1491. Further, we declined to extend the

Supreme Court’s Johnson void-for-vagueness analysis to the similarly, but not identically,

worded residual clause of § 924(e), and instead upheld the residual clause. United States v.


facilitate the robbery is too circumstantial.

However, “juries may consider circumstantial evidence and draw reasonable inferences from

such evidence.” United States v. Washington, 715 F.3d 976, 980 (6th Cir. 2013). The testimony

was sufficient to support the reasonable inference that Tibbs aided and abetted the robbery by

providing assistance with the requisite intent.

                         2. Aiding and abetting possession of a firearm

       Next, Tibbs challenges the evidence to support that he aided and abetted the brandishing

of a firearm during the robbery. Where a defendant is charged with aiding and abetting a

§ 924(c) firearm offense, “the government makes its case by proving that thegovernment then read a question from the grand

jury proceedings: “But he, meaning Christopher Tibbs, knew a gun was going to be involved.

And, in fact, advised you to use a gun.” Id. at PID 519. Baker had responded: “Yes, sir.” Id.

Asked at trial whether he recalled that testimony, Baker said: “I remember something like that.

Yeah, I remember something like that.” Id. Before the grand jury, Baker had also testified:

“[H]e knew a gun was going to be used.” Id. at PID 533. When the government read this

testimony at trial, Baker answered: “Right,” although he proceeded to explain his view that

Tibbs “was basically putting in input.” Id.

       Tibbs has not shown that no rational trier of fact “could have found the essential elements

of the crime


at the bottom of the Guidelines

range. United States v. Odeh, 815 F.3d 968, 984 (6th Cir. 2016).

                                               -21-
No. 15-1060, United States v. Tibbs

                                      IV. Conclusion

       For these reasons, we AFFIRM Tibbs’s conviction and sentence.

     the local circular speed is 238[kms$^{-1}$]{} [@schoenrich2012]. Figure \[fig:N\] shows the spatial distribution of the young (left panel) and old (right panel) stars in $X$–$Y$ plane, in which $X$ points from the Galactic center to the outskirt of the disk through the Sun and $Y$ points to the direction of the rotation of the disk. Noted that this right-hand coordinates does not fit the usual direction to look at the Milky Way, i.e. looking it from north Galactic pole. Hence, in all rest figures in this letter, we flip the direction of $X$-axis so that the Milky Way is looked from the north Galactic pole and the direction of the rotation is upward. The samples are located within 0.6kpc around the Sun. Thus, $Y$ is approximately equivalent with the azimuth


themselves with a density wave.

This scenario is not conflict with the mean age for the young tracers, which is only $\sim2$Gyr. Such a time scale is within the expected lifetime of the transient spiral structures [@sellwood2014].

Moreover, the distributions of the in-plane velocities displayed in Figure \[fig:vrvphi\] show that, for the young stars (panel a), the velocity distribution forms a tight arc shape. By contrast, the old stars (panel b) show an extended and roughly featureless distribution with a moderate bump at around [$v_R$]{}$\sim30$[kms$^{-1}$]{} and [$v_\phi$]{}$\sim180$[kms$^{-1}$]{}, which should be the Hercules stream [@dehnen2000; @xia2015]. The velocity distribution shown in panel (a) can be qualitatively compared with the simulations from @quillen2011. We find that the orientation of the arc similar to our sample is located at the inter-arm regime (see the panels at the 3rdthat facilitates collaboration across industries and government entities. For example, to measure the nation’s cybersecurity efforts there needs to be a diverse membership comprised of federal and state regulators with responsibility for oversight of publicly/privately owned facilities, privately owned and operated suppliers, crisis-level and regional management authorities, and other parties.

The membership should be familiar with the International Standards Organization (ISO) standards, and in every case, experienced with implementation and auditing organizations and facilities that have chosen to adopt voluntary, standards-based management systems.

This membership should have interests conforming to the voluntary frameworks exemplified in the Plan-Do-Check-Act models common to quality, environmental, health, safety and security standards of the ISO.

It will take both the private and public sector’s best and brightest to collaborate and address the increasing cybersecurity threats. The


90 So.2d 604 (1956)
Alfred E. SHORR, a single man, Appellant,
v.
William C. SKAFTE and Helen Skafte, his wife, Appellees.
Supreme Court of Florida. Special Division B.
October 24, 1956.
Rehearing Denied December 4, 1956.
Daniel G. Satin, Miami, for appellant.
Rogers, Towers, Bailey & Jones, Taylor Jones and Bette Towers Miller, Jacksonville, for appellees.
THOMAS, Justice.
The appellees were plaintiffs and the appellant was defendant in the chancery court. In this opinion we will refer to the parties as they were there designated. The suit was one to foreclose a mortgage and in the complaint it was alleged that the instrument was given 25 October 1951 to secure a promissory note evidencing an indebtedness of $6000. The note was payable six months after 1 November 1951 "with interest * * * at the rate of NONEInternal initiation of mRNA translation in insect cell mediated by an internal ribosome entry site (IRES) from shrimp white spot syndrome virus (WSSV).
Internal initiation of mRNA translation can be mediated by internal ribosome entry site (IRES) elements which are located mainly in RNA viruses as well as certain mammalian and insect mRNA molecules. Thus far, only one DNA virus has been discovered to contain IRES element. In this investigation, an IRES element from white spot syndrome virus (WSSV), a DNA virus of marine shrimp, was demonstrated to direct the efficient translation of dicistronic mRNA in Trichoplusia ni insect cells. The IRES was inserted between glutathione S-transferase (GST) and green fluorescent protein (GFP) genes to construct a dicistronic cassette (GST-IRES-GFP). After transfection of this dicistronic cassette in insect cell,


stage was stable, accounted for almost 50 and 20 % of the total, respectively. Adolescents turning no depressive symptoms to depressive symptoms were mostly in 6-12 months, followed by 18-24 months. Additionally, girls (OR 1.24-1.37), post-disaster negative life events (OR for high vs. low = 5.54-15.06), resilience (OR for low vs. high = 9.40-13.69), and depressive symptoms at previous stage (OR 4.96-6.03) had a long-term effect on depressive symptoms, while the impact of earthquake exposure diminished with the passage of time and could not predict depressive symptoms after one and a half years after the earthquake. Among adolescent survivors, the resistance and persistence of depressive symptoms were common. Moreover, depressive symptoms tended to outbreak close to the anniversary date, showing the anniversary reaction. Adolescent girls, adolescents who encounteredThe long-term objectives are to make correlated studies of facial form and masticatory function in the presence of experimental variables, and to formulate from these studies new concepts for the diagnosis and treatment of severe malocclusion and jaw dysfunction. Alterations of facial growth and masticatory function will be produced experimentally in monkeys by means of mechanical forces and experimental brain lesions. Documentation of changes in form will be cephalometric and histologic; function will be studied by mandibular tracking combined with EMG analysis.


Q:

Number of pairs that can be made with X elements without repeating a pair?

I would like to make pairs out of X number of database objects.

Order of pairs does not matter.
Pairs will be made over multiple rounds.
I do not want pairs to be repeated in a subsequent round.

If I have:
A
B
C
D

The first round might be:
AB
CD

Second round might be:
AD
CB

Third round might be:
AC
DB

And there would be no other possibilities.
So for 4 elements, I could do 3 rounds before I have to repeat a pair.
What is the formula to help me with this for any number of elements?
Related How do I get the total number of unique pairs of a set in the database?

A:

You can use round-robin tournament algorithm to generate all possible pairs. Your example shows r-r algoIntroduction {#s1}
============

The Journal Impact Factor (JIF) was originally developed to help libraries make indexing and purchasing decisions for their journal collections ([@bib18]; [@bib3]; [@bib20]), and the metric's creator, Eugene Garfield, made it clear that the JIF was not appropriate for evaluating individuals or for assessing the significance of individual articles ([@bib17]). However, despite this and the various well-documented limitations of the metric (e.g., [@bib36]; [@bib27]; [@bib6]; [@bib44]; [@bib23]; [@bib39]; [@bib20]; [@bib42]), over the past few decades the JIF has increasingly been used as a proxy measure to rank journals -- and, by extension, the articles and authors published in these journals ([@bib10]). The association between the JIF, journal prestige, and selectivity is strong, and has led academics to covet publications in journals with high JIFs ([@bib19]). Publishers, in


of the JIF, but originating from different academic units. Overall, 17% of institutions had at least one neutral mention. Examples of supportive and cautious mentions can be found in the following two sections. Examples of neutral mentions are in the supplemental information.

What do RPT documents assume the JIF measures? {#s3-3}
----------------------------------------------

### Associating the JIF with quality {#s3-3-1}

The most commonly specified association we observed in these RPT documents was between the JIF and quality, seen in 63% of institutions overall ([Table 2](#table2){ref-type="table"}). By institution type, 61% of R-type and 71% of M-type institutions in our sample that mention the JIF associate the metric with quality. This association can be seen in the guidelines from the Faculty of Science at the University of Alberta that state: "Of all the criteria listed,be a factor in calculating the prevalence of the use of the JIF. However, given our stratified random sampling approach, we consider our sample to be representative and a good indicator of what would be found in the larger population of U.S. and Canadian universities. Importantly, we note that the results differ depending on institution type, which might suggest that the experiences at R-type universities (where mentions of the JIF were most prevalent) play an outsized role in discussions about evaluation. Furthermore, the analysis we present on the terms in groups 1 and 2 of our coding terminology (see [Figure 1](#fig1){ref-type="fig"}) may represent only the tip of the iceberg. That is, while we analyzed only those terms that were very closely related to the JIF, we also observed


correlation ([@bib41]) between statistical power and the JIF.

Several studies have looked at experimental design to assess methodological rigor and quality of a study. [@bib11] analyzed clinical trial studies for 10 different indicators of quality, including randomization and blinding, and found that less than 1% of studies met all 10 quality criteria, while the JIF of the journals did not significantly predict whether a larger number of quality criteria were met. [@bib5] used three different scales that take into account experimental design, bias, randomization, and more to assess quality, and found no clear relationship between the JIF and study quality.

Reproducibility could be used as a measure of quality, since it requires sufficient methodological care and detail. [@bib8] analyzed molecular biology studies and found key methodological details lacking, reporting athe woman who killed herself, the woman who murdered Mr. Ricoletti and the body on hand have all been positively identified as Emelia Ricoletti. Confused, Holmes loses interest in the case. When the bride apparently returns to murder other men, he deduces that these are copycat crimes.

Months later, Holmes' brother Mycroft refers to him a case: Lady Carmichael's husband, Sir Eustace Carmichael, received a threatening warning in the form of an envelope full of orange pips. Sir Eustace is uncooperative, describing his wife as "hysterical"; Holmes and Watson stake out the house for the evening. A ghostly-looking bride appears and disappears in front of them, and the pair hear the sound of breaking glass, followed by screams from both Sir Eustace and Lady Carmichael. They discover Sir Eustace, stabbed to death, by what


in the delivery of rehabilitation services in all parts of Canada and services are not well documented.

"Research tells us that balance can be tested safely and new techniques for fall prevention are being developed by researchers in Canada that should be adopted as soon as possible," says Dr. Mark Bayley of the Toronto Rehabilitation Institute.

"Specialized rehabilitation can substantially improve how well a patient recovers after a stroke," says Dr. Antoine Hakim, CEO and Scientific Director of the Canadian Stroke Network. "Given the potential impact that appropriate rehabilitation can have, gaps in care need to be addressed to ensure all patients have access to appropriate rehabilitation.''

Dr. Michael Hill from the Heart and Stroke Foundation encourages people who have strokes and their families to be actively involved with the strokedisease and other types of dementia. But non-drug approaches actually work better, and carry ... full story

Mar. 20, 2014 — A professor of physical therapy will use a five-year, $1 million grant to develop a computerized treadmill program that could be used in physical therapy offices to prevent falls and fall-related ... full story

Sep. 11, 2012 — There is now strong evidence that some interventions can prevent falls in people over the age of 65 who are living in their own homes. However, the researchers who reached this conclusion say that ... full story

July 6, 2011 — While falls are a common cause of injury, particularly in older, hospitalized patients, some may not be as preventable as once thought. According to a new literature review, many of the


artist Lindsay Dye, who twerks rhythmically on a “vajazzled cake” she baked with her own hands, singing along to Kate Bush’s “Wuthering Heights.” The audience goes wild, singing and throwing dollar bills, which mix in with the frosting as she rubs cake all over her haunches.

The bar morphs into a dance party, and I head to the afters, only to get briefly trapped in the elevator of the Yuppie Tower on the Williamsburg shoreline where Rachel has lived for four years. “Oh, it still smells like it smells,” says whoever was stuck in the elevator with me. What it smells like is sex, I think, and on cue I hear, “Oh, I think Rachel’s in the other room fucking.”

Photo: Brian Finke

A “Blue of Noon” cursive neon sign hangsfrom swollen feet.

The most common foot problems that elderly people will encounter are bunions, calluses, corns, hammertoes, heel pain, and foot problems related to diabetes. Some other issues include arch pain, tarsal tunnel syndrome, Achilles tendonitis, and Morton’s neuroma

An annual foot examination is a great way for you to ensure that you do not have any serious health problems with your feet. You should talk to a podiatrist about the available treatment options for whichever foot issue you are dealing with.

Diabetes affects millions of people every year. Blood vessels located all over the body are damaged due to diabetes—even the blood vessels of the feet. Neuropathy, or nerve damage, can result from slower blood flow in the legs and feet. In diabetic patients, neuropathy is very important to


survey programs comprising millions of targets and using different spectral resolution will coexist within a field of view populated by thousands of fiber positioners. We then describe the tools needed at each step to support the operations staff and the science community (see section \[sec:tools\]). The science requirements on observing efficiency and calibration and their flow down to the operations concept are then briefly presented in sections \[sec:obseff\] and \[sec:calib\].

Organization {#sec:org}
============

The MSE staff is envisioned as being divided into five functional groups: Administration & Finance, Facility Operations, Instrument Operations, Software Operations, and Science Operations, each defined by their skill sets, specialties, and role in the organization. The groups share observatory resources and work collaboratively in support of each other. This section summarizes their role.

ADMINISTRATION & FINANCE GROUP
------------------------------

The Administrationthe MSE project, we have focused on the maintenance of the segmented mirror, which will be a novelty for the operations staff at CFHT.

It has been common practice for decades to regularly clean the primary mirror of a telescope to maintain a high reflectivity and thus a high throughput of the system. At CFHT, a CO$_2$ cleaning is performed after each instrument exchange, about once every two weeks. At Gemini, a CO$_2$ cleaning is performed weekly but an additional in-situ wash is done every six months to one year (see Ref. ). An in-situ wash implies a standard contact-wash with natural sponges and neutral soap, followed by deionized water rinsing and drying (using small air knives). At the Hobby-Eberly Telescope, a CO$_2$ cleaning that requires two to three hours


arms. This flexibility will improve the utility of the science data gathered by MSE. It is also expected that for most surveys, more than one OM will be required before observations in a particular area of the sky are declared complete.

![\[fig:OS\] Diagram showing examples of envisioned sequence of exposures for MSE’s low-resolution spectrographs.](mse_observingsequence.png){width=".75\linewidth"}

Observing Sequence
------------------

There are two essential and related properties to keep in mind about an OS, to keep it both simple and versatile. First, within an OS, different exposure time sequences on each spectrograph and different exposure times on each arm within a spectrograph can be used. Second, an OS, and thus an OM, will stop when the longest exposure from any arm of any spectrograph is read.

Different exposures times on each spectrograph and arm will helpshows the current user interface to the ETC. The user can chose the spectrograph (LR, MR, or HR), define the source via templates, and the observing conditions. The ETC can be found at [[etc-dev.cfht.hawaii.edu/mse/index.html](etc-dev.cfht.hawaii.edu/mse/index.html)]{}. In its current version, the ETC for MSE can either provide the SNR at all observed wavelengths given an exposure time, or provide the time required to reach a given SNR at all wavelengths. The ETC relies heavily on the systems budgets for throughput, noise, and injection efficiency (see Ref. , , and for more details).

The ETC will also be used during operations to predict the time required to reach a given SNR on a given target under the actual conditions experienced at the summit. The results from the ETC will be compared to those


allocation process for the HR positioners. The targets in the field were selected from the SDSS DR9 catalog near $(RA, DEC) = (30, +62)$ and only targets with a $u$-band magnitude between 19.5 and 20 were kept. In this example, 3032 targets can be reached by an HR positioner out of the 4878 targets provided by the user and surrounding the field of view. There are 1026 HR fibers that can reach a target out of the 1083 HR fibers in the field of view. Working with those, the TAS found 1019 pairs on the first iteration. The numbers of allocations after each iteration are shown in Table \[tab:tas\]. From one simulation to another, using the same target list and input parameters, we noticed that the results areautomatically associate flags to each spectrum that indicate its quality and its utility for science measurements.

The QA will be based on the data themselves, using in particular the estimation of the signal-to-noise ratio (SNR) derived by the ADRP, on the engineering and environmental data. A significant discrepancy between the expected SNR (via the ETC, see section \[sec:etc\]) and the measured SNR will be flagged. The exact nature of the flag will depend on the reason(s) for the discrepancy, which will likely be found in engineering and environmental information. The ADRP will need access to weather conditions, either via the weather sensors or via measurements made using the Acquisition and Guiding Cameras (AGC). The ADRP will thus be able to provide an estimate of the sky background, extinction, and


value for any OE entered in PH2 (see section \[sec:ph2\]). The status flag may also indicate a “completion” rate for each OE, as the ratio between the observed SNR and the required SNR, or between the number of visits executed and the number of visits required. Other definitions will be developed as necessary.

The status flag is a critical piece of information for the OMG to perform properly. Completed OEs will by default not be scheduled anymore. Started OEs will likely receive a higher priority, to provide a higher completion rate for the program it belongs to. Ideally, MSE will observe each OE until it has reached the requirements entered in PH2 (e.g. SNR goal or number of visits), and then flag that OE as “completed” in the OED.In reality, some flexibility will be allowed, in agreement with the priorities defined by the Science team.

### Data distribution

The ADRP will automatically add data products to the ODR and SPA. The MSE staff and the Survey team will have access to all MSE data, although we expect there might be a delay between the time some data products are available to both groups, as the MSE staff first needs to validate the data.

Level 0 and Level 1 data products will immediately be saved into the Observatory Data Repository (ODR) and Science Products Archive (SPA) after each readout to become accessible to the MSE staff for quality analysis and to the Survey teams for preliminary science analysis. Level 2 data products will immediately be saved into the Observatory Data