Vertebrate homologs of Mad and sma have been termed Smads (Derynck et al., Cell 87:173, 1996) or MADR genes (Wrana and Attisano, Trends Genet. 12:493-496, 1996). Genetic alterations in Smad2 and Smad4/DPC4 have been found in specific tumor subsets, and thus Smads may function as tumor suppressor genes (Hahn et al., Science 271:350-353, 1996; Riggins et al., Nature Genet. 13:347-349,1996; Eppert et al., Cell 86:543-552, 1996). Smad proteins share two regions of high similarity, termed MH1 and MH2 domains, connected with a variable proline-rich sequence (Massague, Cell 85:947-950, 1996; Derynck and Zhang, Curr. Biol. 6:1226-1229, 1996). The C-terminal part of Smad2, when fused to a heterologous DNA-binding domain, was found to have transcriptional activity (Liu et al., Nature 381:620-623, 1996; Meersseman et al., Mech. Dev. 61:127-1400, 1997). Theanimals is by measuring brain temperature. Brain temperature measurement is the key and universal indicator of both disease and health equally, and is the only vital sign that cannot be artificially changed by emotional states. The other vital signs (heart rate, blood pressure, and respiratory rate) all can be influenced and artificially changed by emotional states or voluntary effort.
Body temperature is determined by the temperature of blood, which emits heat as far-infrared radiation. Adipose tissue (fat tissue) absorbs far-infrared and the body is virtually completely protected with a layer of adipose tissue adherent to the skin Thus measurement of temperature using the skin did not achieve precision nor accuracy because previous techniques used sensors placed on skin characterized by the presence of adipose tissue.
Because it appeared to be


potential abuse, though, Field says, “They need to let the kids be physically affectionate to each other,” or at the very least, ensure they get exercise. Stimulating the pressure receptors under the skin through exercise, Field believes, can provide some of the same beneficial effects as getting a massage or getting a hug.

In one particularly harrowing scene in a Washington Post dispatch from the border, a shelter worker refrains from touching, hugging, or picking up a 2-year-old recently separated from her mother as she screams and pounds her fists on a mat. “We all knew what the problem was,” Colleen Kraft, who witnessed it, told the Post. “She didn’t have her mother, and none of us can fix that.” Certainly not, but the scene raises a compelling question:The protein alpha-Synuclein (aSyn) is highly-studied due to its role in Parkinson\'s disease (PD) and its accrual as the major protein component of Lewy bodies/Lewy neurites (LB/LN) (Anderson et al., [@B1]). Though the precise role of aSyn in disease pathogenesis is not fully elucidated, aSyn toxicity is widely thought to be associated with its aggregation in LB/LN. This has led some to consider modulating aSyn expression as a means to counteract PD pathology. Yet, a multitude of studies show that altering aSyn expression or removing it from neurons has profound effects on many intracellular processes and in some cases induces neurodegeneration. This leads some to propose that normal aSyn function is crucial for particular neuronal populations and that PD results from a toxic loss of aSyn function (Perez


CEO of R&R Perez, LLC and declares that this editorial and any research described was done in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

The Topic Editor would like to acknowledge major contributions of Drs. Fredric Manfredsson and Ivette Sandoval to the success of this Research Topic. Thanks to the efforts of these Co-Editors this important topic was brought to life, allowing the scientific community to participate in an open discussion regarding aSyn roles in wellness and disease.

**Funding.** This work was supported by National Institutes of Health R01-NS42094, NINDS to RP.

[^1]: Edited and reviewed by: Wendy Noble, King\'s College London, United Kingdom

[^2]: This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience

[^3]: †Present address:more straightforward than Ann’s. Saxis the archetypal master planner: an ivory tower scientist and technocrat. To Sax, Mars could be any place. What matters is that humanity, with its technology, its knowledge and the superiority of sentience and self-consciousness, has arrived. In one of the early exchanges about the human role on Mars, still on the trans- port from Earth, two proclamations sum up Sax’s early relationship with the planet: ‘We’ll change it just by landing’ and ‘It’s dead’ (Robinson 1993: 40). Once humans arrive on Mars, the process of change will be underway, it will be irreversible and it will be for the better. Sax elaborates on these sentiments in a debate with Ann.

Without the human presence it [Mars] is just a random collection of atoms, no


atmosphere, intensifying and speeding up the warming of the planet, but making it uninhabitable for animal life. ‘As if warming the planet was the only goal! But warming was not the goal. Animals on the surface was the goal’ (Robinson 1995: ISO). His commitment to life, articulated in Red Mars, sharpens here. It is not only human life, but life in general that matters to Sax. However, many of the more drastic, and apparently ascendant, terraforming plans are centred on a heavy industrial model that would heat the surface and thicken the atmosphere as fast as possible. This would make the planet eminently exploitable, unveiling mineral ores and enabling activities on the surface other- wise inhibited by cold, but it would not support the introduction of life inthink about a lot. Until the end, this exchange is much like the others between the two of them. Sax defends the terraforming in principle. He reasserts a plan for a ‘human-viable surface to a certain elevation’ and a slower approach to transforming the surface and the atmosphere. Ann is curious about his decision to knock out the one portion of the heating device, but is still bitter about the terraforming and Sax’s commitment. But this time Sax ends with this admission: ‘I was wrong... We should have waited. A few decades of study of the primal state. It would have told us how to proceed. I didn’t think things would change so fast.’ Ann, non-plussed, simply responds: ‘But now it’s too late’ (Robinson 1995: 415). This exchange,


evolution of life on the planet.

Mars itself undergoes yet another revolution in Green Mars, only this time Mars breaks free from Earth. In Blue Mars, the independence movement must now address issues of Martian governance and what sort of relationship to establish with Earth. Both of these decisions shape the context for addressing Sax’s and, especially, Ann’s personal transformations and their respective relationships with the planet that has become their home. Indeed, in Blue Mars, Sax and Ann emerge as the trilogy’s principal characters. Sax’s focus in Blue Mars is on deepening his understanding of Ann’s connection to Red Mars and finding an entry to persuade her that life on Mars is not a blight, but a beautiful and right thing.

It is clear in Blue Mars that Martianmeeting Tuesday of the Auglaize County Health Board, the following were approved;
â€˘ Renewal of contracts for school nursing with Minster and New Knoxville for the 2013-14 school year at the same rate.
â€˘ Renewal of contract with Stephanie Mosler for family planning pharmacist services. Mosler typically works between two and three hours a month writing prescriptions.


Prevalence of cigarette smoking in young Nigerian females.
Cigarette smoking is a very important public health problem globally, with patterns of smoking varying in different regions of the world. The negative impact of smoking on health is well known but the increasing rate of smoking amongst the youth including females is note worthy. The objective of this study is to determine the prevalence of smoking in young Nigerian females with a view to defining the size of this social problem and outlining possible control measures. The setting for the study was secondary (post-primary) schools in Anambra State, South east of Nigeria. The study, a cross-sectional survey, involved eight (8) schools selected by multistage sampling technique. A Structured questionnaire was designed for the study. A total of 1,200 female secondary      <xsd:element name="resheader">
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   know that means Rita is lying." "Yup." "Don't like the look of it." "What's the plan, Walt?" "I was thinkin' I should talk to Rita." "That ain't a good idea, Walt." "We gotta call Washington." "I'll talk to him first thing in the morning." "I need..." "Alright, alright." "You gonna come in for a beer?" "No." "Gonna tuck in." "Alright." "Walter." "'Evenin'" "'Evenin' Rita." "Sorry to be um" "You can't come 'round like this." "No I" " I know, I know it." "Hey, hey" "Jury, Jury, in the house, in the house, come on." "God damn dog ain't got no damn sense inside him." "This Steve, he here full-time now?" "That ain't none of your business, Walter." "And you can't come by the house no more." "I'm done


a dog had done it, they'd put him down." "You think that's fair?" "Is that justice?" "Or just a waste of time?" "Dear Lord, we give thanks for the food before us and the shelter over our heads." "We thank you for your guidance and your love." "Amen." "Amen." "Jan is scared out of her wits, says she won't let the kids go swimmin' because of it." "Not 'til she knows who done it." "You believe that?" "Like the whole lake is contaminated or something." "You think Terry McNeil is going to stop parking up at the Point Please." "I swear that boy didn't wait 12 hours before he was boasting about doing his business up there." "There's gotta be a fine or somthing for that right?" "Boy."done." "I know what you done." "Fuck that's it, I'm calling Jim." "You're not calling" "Walter!" "Walter!" "Walter!" "No!" "Steve!" "Fuck!" "Leave him be goddamnit!" "He's already fucking down!" "Let go!" "How's Rita?" "You're gonna have to come with me." "I almost" " I could have put him down." "But, I'm not an animal." "I can't be like that anymore." "He did it, right?" "You think I did the right thing?" "No." "But whatever you did, Rita turned Steve in."


either dependent or aided by SP-A. Aim 1 will determine the "offensive" strategies orchestrated by PA's flagellum, PchA and PtsP to confer resistance to SP-A-mediated membrane permeabilization. These offensive measures to be tested include the ability of PA to secrete proteases that degrade SP-A, and to secrete salicylate that strips Ca2+ associated with SP-A, which is required for the activity of SP-A. Aim 2 will determine the "defensive" strategies orchestrated by PA's flagellum, salicylate/pyochelin and phosphoenol-pyruvate phosphotransferase to confer resistance to SP-A-mediated membrane permeabilization. The defensive measures to be determined include increased LPS biosynthesis and modification, and chemotaxis evasion. Aim 3 will examine the hypothesis that during the initial interactions, SP-A preemptively "paralyzes" PA, allowing other AMPPs to act synergistically or additively to kill the bacteria. We willSavannah Marshall is convinced that she would make it two wins from two fights against Claressa Shields if the former amateur rivals were to meet again in the professional ranks.

Undefeated Hartlepool sensation Marshall, trained by Peter Fury, makes her highly-anticipated Matchroom Boxing debut this Saturday when she takes on Brazil's Daniele Basteri over eight rounds in a Super-Middleweight contest, live on Sky Sports Box Office.

The 28-year-old ‘Silent Assassin’ remains the only boxer to have inflicted a ring defeat on undisputed Middleweight World Champion Shields. Marshall outpointed the US golden girl in China on route to cementing herself as Britain's first ever female amateur World Champion in 2012.

She was last seen demolishing tough Bulgarian Borislava Goranova in one round at Victoria Warehouse in May and believes her link up


How to Transplant a Sycamore Tree

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How to Transplant a Sycamore Tree

Overview

The American sycamore tree (Platanus occidentalis) is a tall, fast-growing tree that commonly reaches heights of 50 to 60 feet, but has the potential to reach 150 feet. The flaking bark of a sycamore is an eye-catching feature; however, its peeling bark, extremely large leaves (up to 10 inches wide) and seed heads make it a messy tree, unsuitable for many yards. It needs a deep, rich soil and is not drought-tolerant. Sycamore trees are easily transplanted.

Step 1

Prune the roots at least one season (autumn or spring) before transplanting. Measure the thickness of the trunk stem and draw a circle around the stem 10 to 12 inches out for every 1 inch of stem thickness. Forexample, a 1-inch caliper (measurement of thickness taken roughly 6 inches above the ground) tree would have a circle diameter of 20 to 24 inches around the stem. Sink the blade of the digging spade as deep as possible all the way around the circle.

Step 2

Dig up the tree one season after pruning the roots. Dig down a few inches outside of where the root-pruning trench was dug the previous season. Pry the roots and loosen the soil while digging down. It may help to moisten the soil the day before.

Step 3

Slip under the roots with the shovel or use loppers to cut any roots that may be growing downward. The transplant should now be able to be moved to the new location.

Step 4

Cover the roots with wet


case when the electronic device is subjected to impact, such that the removable peripherals become loose and slip in the case, resulting in the damages of the removable peripherals and the case due to rubbing against each other. Meanwhile, the removable peripherals are liable to impact the movable door panel structure and fall out of the case through the opening, which causes the damages of the movable door panel structure and the removable peripherals at the same time.
Currently, in order to solve the problem, a hook structure having elastic restoring force is configured at the opening of the case or the shield for securing door panel structure, such that the removable peripherals is locked by the hook structure or blocked by the fixed door panel structure, and thusfind periodic solutions of (\[op1\]). In fact, it is easy to see $u=0$ is not a solution of (\[op1\]) if $\epsilon\neq0$. Hence it is meaningful to look for periodic solutions of (\[op1\]) with positive $\epsilon$.

We have the following main result.

\[mthm\] For any $\delta>0$, there is some $\epsilon_0>0$ depending only on $\delta,f,g,m,p,d$ such that, for $0\leq\epsilon\leq \epsilon_0$, there exists a set $\Omega=\Omega{(\epsilon)}\subset [1,2]^{d}$ of Lebesgue measure $\mathrm{mes} ([1,2]^{d}\setminus \Omega)\leq \delta $ such that, for $\nu\in \Omega$, $\mathrm{(\ref{op1})}$ admits an analytic solution. More precisely, for any $\nu\in \Omega$, there exists some $u_{\nu}\in C^{\omega}(\mathbb{T}^{d},\mathbb{R})$ so that $u_{\nu}(x)$ is a solution of $\mathrm{(\ref{op1})}$.

To prove the existence of solutions for a nonlinear elliptic equation, methods of the calculus of variations, bifurcation theory and topological degree have been used. By contrast, we will make


[@WMWF] and Yuan [@Yuanar].

Regarding the methods, we use mainly the Nash-Moser iterations in [@BB2005] as well as the Green’s function estimates developed by Bourgain [@B2007]. As is well-known, the key to the Nash-Moser iterations is the appropriate estimates on the inverses (or Green’s functions) of the linearized operators. If we regard $(\nu_1,\cdots,\nu_d)$ as parameters, then the *covariance* property (see (\[cov\]) in section 3) holds. More importantly, in this case the Green’s functions are quite similar to that in the study of Anderson localization for quasi-periodic operators on $\mathbb{Z}^d$. This observation may lead to good controls of the Green’s functions, i.e., off-diagonal *exponential* decays of the Green’s functions. Let us recall briefly some Anderson localization results. For $d=1$, Bourgain-Goldstein [@BG2000] originally established the non-perturbative Anderson localization for general quasi-periodicso that $$\mathrm{diam}(\Lambda)\sim N, \mathrm{diam}(\Lambda_1)\sim N^{\frac{1}{2d}}, \ m\in \Lambda_1\subset \Lambda,\  \mathrm{dist}(m,Q_{\overline{N}}\setminus \Lambda)\geq\frac{N}{2},$$ and $$\begin{aligned}
    &&||G_{\Lambda\setminus \Lambda_1}^u(\theta)||\leq e^{3N_2^\kappa},\\
    &&|G_{\Lambda\setminus \Lambda_1}^u(\theta)(n,n')|\leq e^{-(\rho-\overline{N}^{-\frac{\tau_2}{2}})|n-n'|}\ \mathrm{for}\ |n-n'|>N_2^{1+}.
     \end{aligned}$$

Finally, we introduce the powerful matrix-valued Cartan estimate with $1$-dimensional parameters. For a generation to several variables case, we refer to [@JLS].

\[mcl\] Let $T(x)$ be a self-adjoint $N\times N$ matrix function of a parameter $x\in[-\delta,\delta]$ satisfying the following conditions:

-   $T(x)$ is real analytic in $x\in [-\delta,\delta]$ and has a holomorphic extension to $$\mathcal{D}_{\delta,\delta_1}=\{x\in\mathbb{C}: \ |\Re x|\leq\delta,\ |\Im x|\leq \delta_1\}$$ satisfying $$\sup_{x\in \mathcal{D}_{\delta,\delta_1}}||T(x)||\leq B_1.$$

-   For all $x\in[-\delta,\delta]$, there is subset $V\subset [1,N]$ satisfying the length $$|V|<M,$$ and $$||(R_{[1,N]\setminus V}T(x)R_{[1,N]\setminus V})^{-1}||\leq B_2.$$

-   $$\mathrm{mes}\{x\in[-{\delta}, {\delta}]: \ ||T^{-1}(x)||\geq B_3\}\leq 10^{-3}\delta_1(1+B_1)^{-1}(1+B_2)^{-1}.$$


Let $$0<\varepsilon\leq (1+B_1+B_2)^{-10 M}.$$

Then $$\mathrm{mes}\left\{x\in\left[-\frac{\delta}{2}, \frac{\delta}{2}\right]:\  ||T^{-1}(x)||\geq \varepsilon^{-1}\right\}\leq C\delta
 e^{-\frac{c\log \varepsilon^{-1}}{M\log(M+B_1+B_2+B_3)}}.$$

We are ready to prove LDT for Green’s functions.

We first prove the LDT for $G_N^u(\theta)$ if $N$ is not too large.

\[inl\] Define for $\delta>0$ the set $I=\{x\in\mathbb{R}:\ |(x+a)^2+b|<\delta\}$, where $a,b\in\mathbb{R}$. Then $\mathrm{mes}(I)\leq C\delta^{\frac{1}{2}}$, where $C>0$ is an absolute constant.

The proof is trivial and we omit the details here.

\[ildt\] Let $\gamma\in (0,1),\rho>0$. Then there exist $N_0\gg1, \Sigma>1,\kappa\in (0,1)$ so that, for any $u$ satisfying $|u(n)|\leq Ce^{-\rho|n|}$, $N_0\leq N\leq |\log\epsilon|^\Sigma$ and any $\nu\in[1,2]^{d}$, $$\begin{aligned}
&& ||G_{N}^u(\theta)||\leq e^{N^{\kappa}},\\
&& |G_N^u(\theta)(n,n')|\leq e^{-\frac{4\rho}{5}|n-n'|}\  {\mathrm{for} \ |n-n'|\geq \frac{N}{10}},\end{aligned}$$ where $\theta$ is outside a set $X_N\subset\mathbb{R}^{d}$ satisfying for any $1\leq j\leq d,$ $$\sup_{\theta_j^\neg\in\mathbb{R}^{d-1}}\mathrm{mes}(X_N(\theta_j^\neg))\leq e^{-N^\gamma},$$ with $$\theta_j^\neg=(\theta_1,\cdots,\theta_{j-1},\theta_{j+1},\cdots,\theta_{d}).$$

The proof is based on Lemma \[inl\] and a standard Neumann series argument.

We define the following statements ${\bf (S)}_N$ forlast Monday.

The two board additions with airline expertise — James Whitehurst, former chief operating officer of Delta Air Lines, and Robert Milton, former CEO of Air Canada — were previously vetted and mentioned as potential directors by PAR and Altimeter, the people familiar with the situation said.

United also offered to extend a deadline for PAR and Altimeter to propose names to be interviewed for the board, which the funds declined, and United on Feb. 18 amended its bylaws in line with shareholder interests, two of the people said.

Brad Gerstner, CEO of Altimeter Capital, called United's proposal "a cynical attempt to preserve power by this entrenched board," in a statement on Tuesday.

However, United and the hedge funds are open to a settlement that avoids a vote on the shareholder


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        }

        End();
    }

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    {
        ULONG n = RTL_NUMBER_OF(_hEvent);
        do
        {
            if (HANDLE hEvent = CreateEventW(0, n > 2, 0, 0)) _hEvent[--n] = hEvent;
            else return GetLastError();
        } while (n);

        return NOERROR;
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   Q:

Getch in combination with while-loop triggers loopcontent twice

I'm not really a programmer so my knownledge is extremely limited, I'm just hoping to get a very basic program working for a project. I've been googling around a lot and from what I've found I'm guessing it has to do with getch reading blank spaces or new lines as an input or something along those lines. None of the solutions I have found seem to fix the issue for me however (I might be implementing them wrong though).
This is in the main function:
while (roundNum <= 20)
{

    roundNum++;

    cout << roundNum / 2 << endl;
    arrowKey();

}

And the arrowKey function (which I found by googling so I don) looks like this:
int arrowKey()
{


}
    return 0;
}

The problem is that the roundNum reads out twice as well as adds two to the number for every arrow key press, like this:
 1
 1

 Up
 2
 2

 Right
 3
 3

etc
Help is greatly appreciated!

A:

The problem is that a char can only hold 255 values. Thus, in order to get more unique values getch sometimes uses two values to represent a key code, an instruction and a value. For example, try hitting the F keys and you'll notice the same issue arise.
Ultimately, the behavior you are experiencing is due to the fact that getch is being called twice for the arrow keys.
To fix this, check if the instruction is for the arrow keys, in this case the value is 224 for theA major challenge for mammalian hosts is to maintain symbiotic relationships with the vast bacterial communities that colonize the intestines. The intestinal epithelium is the primary barrier between the intestinal microbiota and internal host tissues, yet little is known about how epithelial cells control bacterial interactions with the mucosal surface and limit microbial penetration of the intestinal barrier. We have discovered a novel antibacterial factor, RegIIIg, which is produced by small intestinal epithelial cells. RegIIIg is a member of the C-type lectin family of carbohydrate-binding proteins that is discharged into the gut lumen. RegIIIg has direct bactericidal activity against Gram-positive bacteria and binds its bacterial targets via interactions with peptidoglycan carbohydrate. RegIIIg thus represents a previously unappreciated mechanism of mucosal defense and a new biological function for C-type


is desirable, therefore, to use refrigerants which have relatively short atmospheric lifetimes as a result of their ability to react with other atmospheric constituents such as hydroxyl radicals or as a result of ready degradation through photolytic processes.
R-410A and R-407 refrigerants (including R-407A, R-407B and R-407C) have been introduced as a replacement refrigerant for R-22. However, R-22, R-410A and the R-407 refrigerants all have a high global warming potential (GWP, also known as greenhouse warming potential).
1,1,1,2-tetrafluoroethane (refrigerant R-134a) was introduced as a replacement refrigerant for R-12. However, despite having no significant ozone depletion potential, R-134a has a GWP of 1300. It would be desirable to find replacements for R-134a that have a lower GWP.
R-152a (1,1-difluoroethane) has been identified as an alternative to R-134a. It is somewhat more efficient(Lys-8) and ^6^C~13~ ^4^N~15~ arginine (Arg-10) for five population doublings, which yielded over 95% incorporation efficiency. After SILAC labeling of preadipocytes, equal protein amounts of labeled protein lysates were mixed with the experimental condition lysates to generate mixtures of heavy and light (unlabeled) lysates for quantitative proteomics. The experimental conditions included three biological replicates of shSirt1, shScramble, and uninfected 3T3-L1 lysates. shSirt1, shScramble, and uninfected 3T3-L1 preadipocytes grown to 60--80% confluence were harvested and lysed in lysis buffer (50 m[m]{.smallcaps} Tris-HCl (pH 8), 2% SDS, 1× protease inhibitors, 2 μl/ml benzonase, 2 m[m]{.smallcaps} sodium orthovanadate, 25 m[m]{.smallcaps} sodium fluoride, 5 m[m]{.smallcaps} nicotinamide, and 3 m[m]{.smallcaps} trichostatin A). Protein preparations were obtained after sonication and centrifugation. Equal amounts of protein of each of the replicates (100 μg) were mixed


chromosomal replication as the most enriched canonical pathway ([Fig. 4](#F4){ref-type="fig"}*A*). In addition, altered amino acid metabolism signaling pathways and DNA double-strand break repair by homologous recombination were also reported as activated.

![**Focused pathway analysis of proteome changes in SIRT1-silenced preadipocytes reveals enrichment in cell cycle regulatory pathways.** *A*, the top 15 IPA-predicted affected canonical pathways of SIRT1-specific proteome changes. The axes show percentages of overlapped genes in each pathway and the *p* value of overlap (IPA-generated). Highlighted in *red* and *green* is the percentage of up-regulated and down-regulated gene products in each pathway, respectively. *B*, the top five identified up-regulated and down-regulated gene products in the dataset as highlighted in *red* and *green*, respectively. *C*, the top nine affected molecules designated to the cell cycle control of chromosomal replicationfound that differentiating SIRT1-silenced cells incorporated significantly more BrdU (50%) compared with controls shScramble and uninfected cells (37% and 38%, respectively), as shown in [Fig. 6](#F6){ref-type="fig"}, *C* and *D*. These results demonstrate that SIRT1-silenced cells exhibit elevated MCE and delayed MCE exit phenotypes.

#### SIRT1 Reduction Dysregulates MCE and Adipogenic Regulators in Differentiating 3T3-L1 Adipocytes

Protein levels of SIRT1, p27, C/EBPβ, and PPARγ in shSirt1 3T3-L1 preadipocytes undergoing differentiation were evaluated over time ([Fig. 7](#F7){ref-type="fig"}). SIRT1 levels were significantly decreased at all differentiation time points in SIRT1-silenced cells compared with controls ([Fig. 7](#F7){ref-type="fig"}, *A* and *B*). Importantly, SIRT1 expression was increased in control cells at early differentiation stages (d1PDI to d2PDI) but then decreased at late differentiation stages (d4PDI to d6PDI), which suggests that SIRT1 regulates the MCE phase of


were used as loading controls. Results are representative of three independent experiments. *NDI*, no DI. *B--C*, Western blot bands were quantified and normalized to the loading control. *D*, assessment of c-Myc transcriptional activity using a luciferase reporter assay. shSirt1 3T3-L1 cells were transfected with either pMyc-TA-Luc or pTA-Luc plasmids combined with pSV-β-gal plasmids, and, the following day, cells were induced to differentiate. Luciferase activity was measured and normalized to β-gal expression for both proliferating cells and differentiating cells on d1PDI. The luciferase activity for shSirt1 cells was compared with control shScramble control cells. Results are represented as mean ± S.E. of three independent experiments using Student\'s *t* test. \*, *p* \< 0.05; *n.s.*, not significant.](zbc0071636690008){#F8}

To further characterize the mechanism of SIRT1 in driving hyperplasia, we assessed the c-Mycand *I*). We did not observe any phenotypic difference by Oil Red O staining of shMyc-silenced adipocytes compared with shScramble control adipocytes ([Fig. 10](#F10){ref-type="fig"}, *G* and *H--J*). These results suggest that c-Myc knockdown prevents the development of the hyperplastic phenotype induced by SIRT1 knockdown. We conclude that SIRT1 controls adipocyte hyperplasia in a c-Myc-dependent manner.

![**c-Myc reduction prevents the SIRT1 knockdown-induced adipocyte hyperplasia phenotype.** *A* and *B*, Western blotting was performed using antibodies against c-Myc (*A*) and SIRT1 (*B*) for the following conditions of 3T3-L1 preadipocytes: control shScramble, two different constructs for shMyc (*A*), shSirt1 (*B*), and two different combinations of double infection using different antibiotics selections (puromycin (*puro*) and neomycin (*neo*)) (*A* and *B*). *C--I*, Oil Red O staining of differentiated 3T3-L1 adipocytes for the indicated conditions. Nuclei


fat hyperplasia *in vivo* is lacking. Therefore, future work should include an analysis of the function of SIRT1/c-Myc in driving adipocyte hyperplasia in a possibly fat depot-dependent manner in obese subjects. c-Myc has been shown previously to induce gene expression of SIRT1, yet it is a direct SIRT1 target for deacetylation and subsequent destabilization ([@B32]). This leads to a reduction in c-Myc expression and the generation of a negative feedback loop that controls c-Myc-induced cellular transformation ([@B32], [@B39]). In this study, SIRT1 reduction in preadipocytes led to hyperacetylation of c-Myc, which may drive uncontrolled cell proliferation and, as a consequence, may generate hyperplastic dysfunctional adipocytes. The SIRT1/c-Myc axis appears to control the cell number and functional integrity of adipocytes.

The key cell cycle regulator p27 is a repression targettold NBC 7 Friday night. "Show me that my wife had a gun or something that threatened the guy’s life where he had to use lethal force against her."

Alvarado’s family confirmed the warrant had nothing to do with her and the mother of five would never intentionally hurt anyone for any reason.

Alvarado’s cousin, Bernice Ratcliffe, is trying to make sense of something she believes was senseless.

"I think we're all shocked and we want answers,” said Ratcliffe. “"They didn't have to shoot her!”

Witnesses in the area at the time of the shooting told NBC 7 San Diego they saw Alvarado slowly driving in reverse as the agent opened fire on her at least six times.

"As the car was backing up the officer was in the street walking toward the


Q:

Getting wrong text sequence when image scanned by offline google mobile vision API

 public StringBuilder scanImage(Bitmap bp)
    {
        StringBuilder sb=null;
        TextRecognizer tcx = new
        TextRecognizer.Builder(getApplicationContext()).build();
        if (!tcx.isOperational())
        {
            Toast.makeText(getApplicationContext(), "could not get text", Toast.LENGTH_SHORT).show();

        } else
        {
            Frame fame = new Frame.Builder().setBitmap(bp).build();
           deformation problem is less likely to happen.
In addition, due to this invention of the good C.H.P., it is less strainuous physically for the wrist and fingers, so better power and performance of the players can be maintained longer naturally through out the game.
In addition to the published new invention of ‘split-level step’, the C.H.P. concept can be achieved (although it is less ideal compared to the ‘split level step’ design) without adopting the ‘split-level step’ by having ‘raised height’-block or step or ‘prolonged bottom handle’ design in front and/or at the back of the bat (See Y&X in FIGS. 3,4,5,6&7) acting as the C.H.P. as found in the ‘split-level step’. (see X in FIGS. 2,4&7). These ‘raisedheight’ blocks or steps and ‘prolonged bottom handle’ are also claimed and


189 million. Four percent of 189 million is over 7.5 million. According to the 1997 Statistical Abstract, the total number of United Methodists in the United States is about 8.5 million. Thus the number of adult nonbelievers is nearly equal to the total number of United Methodists, the second-largest Protestant denomination. Some fringe group.

Of course, America is a notoriously religious country. If we extend our view worldwide, the percentage of people who don't believe in gods increases dramatically. Many millions of people in Japan and China do not believe in gods. Even if only 1% of the world's people believe in no gods, surely a gross underestimate, that is still 60 million people--hardly a negligible number.

5) Are atheists intolerant of religious people? About ten years ago I addressedan article to the claims of Christian apologist J.P. Moreland. I claimed that atheists did not harangue people on street comers or visit schoolyards to hand out tracts. In general, I claimed, atheists believe in "live and let live" and, unlike fundamentalist zealots, make little effort to proselytize.

Moreland took me to task, saying that he could "only marvel" at my claim that atheists generally were not intolerant of believers. At the time, I could only marvel at his marveling. In the meantime, I'm sad to say, I've encountered some very obnoxious atheists who seem to take delight in attacking any expression of religious belief, no matter how innocuous. So I must concede to Moreland that, yes, atheists can sometimes be as offensive and obnoxious as the most bigoted


for example would have been a good day to own $SQQQ for the day (up
7.3%). Any insight on how to go about this hedge strategy using Alpaca? Can I
get pre-market quotes for the Nasdaq?

------
9712263
Seems inherit the same limitation of RobinHood: you can't do short selling.
Not sure how actually they could do a free commission order, so not sure why
short selling is not supported, but it limits the use of long only strategy.

~~~
anonu
Interesting. I suppose it's a much more involved process where you need to
locate shares to borrow. You need to maintain a list of easy to borrow and
hard to borrow names. ETFs by definition are hard to borrow.

I used to work next to the stock loan desk at a bank. The equity markets are
generally pretty tech driven theseof a good API that does?

~~~
malhotra_chetan
Yes. Narwhal. Narwhal provides commission free flat rate brokerage trading via
tradier and you can trade both in pre and post market hours.

------
hellofunk
How is the access to historical data with these services?

------
kaycebasques
A commission-free trading API? How does Alpaca make money?

~~~
gschier
Likely the same as similar services like RobinHood. A quick Google suggests
they make most of their money on interest from cash sitting around in user's
accounts that has not been invested yet.

~~~
JonasJSchreiber
And by selling info about customer orders to front runners. IIUC, these are
high frequency traders who may place similar orders milliseconds in advance of
yours then profit from the fact that you have to pay a bit more to fill your
order. Full disclosure, I continue to use Robinhood despite this.

~~~
paperwork
This is highly illegal and taken very


seriously. Is this speculation on your
part or do you know this for a fact (in which case, you should report it).

~~~
mjlee
[https://seekingalpha.com/article/4205379-robinhood-making-
mi...](https://seekingalpha.com/article/4205379-robinhood-making-millions-
selling-millennial-customers-high-frequency-traders)

They're probably not front-running. They are almost certainly selling trade
information to HFT firms.

would be reluctant to plunge ahead unless they were reasonably confident they'd get a fifth vote when the case is decided. From the perspective of Trump, and presidential authority in general, it would be better to leave the Second Circuit ruling intact than to have the Supreme Court definitively rule that presidents must comply with such subpoenas.

The lawyers for both Trump and Vance have agreed to submit their court filings promptly. There's no deadline for the justices to act, but both sides are hoping the court will say by mid-January whether it will take the case.

The New York case is one of several ongoing legal battles over Trump's tax returns. Last month, the president's lawyers lost another court battle over his finances. A panel of judges from the


a suction is drawn are mounted with a fixed inter-axial distance is satisfactory in the case of small apparatuses, for example ones with rollers 0.5 to 6 centimetres long, but it has been observed that, in the case of apparatuses in which the roller are longer, the efficiency obtained is less than that attained with the solution in which the rollers can move apart or move towards one another automatically during the massage operation.<BuildableReference
               BuildableIdentifier = "primary"
               BlueprintIdentifier = "97C146ED1CF9000F007C117D"
               BuildableName = "Runner.app"
               BlueprintName = "Runner"
               ReferencedContainer = "container:Runner.xcodeproj">
            </BuildableReference>
         </BuildActionEntry>
      </BuildActionEntries>
   </BuildAction>
   <TestAction
      buildConfiguration = "Debug"


Q:

Show avaiable wifi connections nearby

Can I display the list of wifi access points on UI dialog & allow user to switch wifi settings from within my app by using swift 3?
OR
Is it possible to open the wifi settings on a prompt dialog which does not cover full screen?

A:

No. Check this answer.
It may help you
Objective C
if ([[UIApplication sharedApplication] canOpenURL:[NSURL URLWithString:@"prefs:root=WIFI"]]) {
    [[UIApplication sharedApplication] openURL:[NSURL URLWithString:@"prefs:root=WIFI"]];
} else {
    [[UIApplication sharedApplication] openURL:[NSURL URLWithString:@"App-Prefs:root=WIFI"]];
}

Swift
if UIApplication.shared.canOpenURL(URL(string: "prefs:root=WIFI")) {
    UIApplication.shared.openURL(URL(string: "prefs:root=WIFI"))
}
else {
    UIApplication.shared.openURL(URL(string: "App-Prefs:root=WIFI"))
}

-2/5, -0.45 in increasing order.
k, -0.45, -2/5, 0.1
Let q(w) = 8*w - 49. Let t be q(4). Sort 3, 5, t, -5 in decreasing order.
5, 3, -5, t
Let m be (-12)/9*(-12)/8. Suppose -c - 9 - 7 = 0. Let k be -5 - c/(0 + 4). Sort m, -7, k in decreasing order.
m, k, -7
Let k = 19 - -41. Let a = k + -60.4. Let b = -391/5 - -78. Put b, 5, a in descending order.
5, b, a
Let m(o) = 383*o + 16474. Let f be m(-43). Suppose 0*b = b + 5. Let w = b - -7. Sort w, -1, f in decreasing order.
f, w, -1
Let p = 56 - 85. Let w = -29.02 - p. Sort -4, w, -3 in


be (((-570)/45)/19)/((-2)/(-6)). Sort 3, 15, 5, k.
k, 3, 5, 15
Let u be 22/4 - (-6)/(-12). Let p be (-35)/11 - 32/(-176). Put p, -5, u, 0 in ascending order.
-5, p, 0, u
Let g = -48 + 53. Let a = g - -4. Sort -3, a, -5 in descending order.
a, -3, -5
Let v = -4 - -6. Suppose -19 = 2*o + p, -o = -5*p - 0*p + 37. Let c be 1 + (-16)/o - 2. Put c, -5, v in descending order.
v, c, -5
Let r be 8/10 + (-126)/(-30). Let l = 28 - 28. Sort l, 10, -2, r in descending order.
10, r, l, -2
Suppose 6*m - 4*t - 6 = 4*m, 16 = 4*m - 4*t. Suppose 11 = 2*i + m*u, 5*i+ 303. Let b be t(17). Put 0, -4, b, u in descending order.
u, 0, b, -4
Let w = 422 - 424. Sort -25, w, 3 in descending order.
3, w, -25
Let t be 4/12*-1*-3. Let h be (0 + t)*(3 + (-48)/15). Sort -1, -4/3, h in descending order.
h, -1, -4/3
Suppose 2*x = -5*v - 18, 0*v - 2*v + 4 = -2*x. Let f = -82 + 82.1. Sort x, 3/5, f in decreasing order.
3/5, f, x
Let g be 10*-1*(-11)/(-22). Let q(o) = -3*o**3 - 2*o**2 + 1. Let m be q(-1). Sort 1, 3, g, m in decreasing order.
3, m, 1, g
Let s be (-2)/(-3)*15/(-2). Suppose 12 = -11*g + 56. Sort 1, 2, g, s in ascending order.
s, 1, 2, g
Let t = 509 +


"""
Solve Poisson equation on (-1, 1) with homogeneous bcs

    \nabla^2 u = f, u(\pm 1) = 0

Use Shen basis \phi_k = T_k - T_{k+2}, where T_k is k'th Chebyshev
polynomial of first kind. Solve using spectral Galerkin and the
weighted L_w norm (u, v)_w = \int_{-1}^{1} u v / \sqrt(1-x^2) dx

    (\nabla^2 u, \phi_k)_w = (f, \phi_k)_w

"""
from numpy.polynomial import chebyshev as n_cheb
from sympy import chebyshevt, Symbol, sin, cos, pi, lambdify, sqrt as Sqrt
import numpy as np
import matplotlib.pyplot as plt
from scipy.linalg import solve_banded
from scipy.sparse import diags
import scipy.sparse.linalg as la
from spectralDNS.shen.shentransform import ShenDirichletBasis
from spectralDNS.shen.Matrices import ADDmat
from spectralDNS import config

# Use sympy to compute a rhs, given an analytical solution
x = Symbol("x")
u = (1-x**2)**2*cos(np.pi*x)*(x-0.25)**2
f = u.diff(x, 2)

# Choices
solver = "bs"
N = 21

ST = ShenDirichletFunctionSpace(quad="GC")
points, weights = ST.points_and_weights(N,   for i in range(2, N-2, 2):
            aij.append(np.array(-4*np.pi*(k[:-i]+1)))
        A = diags(aij, range(0, N-2, 2))
        uk_hat = la.spsolve(A, fk)

    elif solver == "bs":
        uk_hat = np.zeros_like(fk)
        A = ADDmat(np.arange(N).astype(float), scale=1.0)
        uk_hat = A.apply_inverse(fk, uk_hat)

    return uk_hat

f_hat = np.zeros_like(fj)
f_hat = ST.scalar_product(fj, f_hat)
uk_hat = solve(f_hat)
uq = np.zeros_like(fj)
uq = ST.backward(uk_hat, uq)

uj = np.array([u.subs(x, i) for i in points])

plt.figure(); plt.plot(points, uj); plt.title("U")
plt.figure(); plt.plot(points, uq - uj); plt.title("Error")
plt.show()


functions are combined, it is needed that each function consumes a low power. However, in the conventional structure, the complexly combined or engaged structure should be physically driven as a whole, which is however inefficient in view of power consumption.Late-phase thromboembolism after catheter ablation for paroxysmal atrial fibrillation.
The aim of this study was to investigate the incidence and predictors (which have not previously been fully elucidated) of late-phase thromboembolism (TE) after catheter ablation (CA) for paroxysmal atrial fibrillation (AF). We studied 1,156 consecutive patients (61±10 years; 891 men; CHADS2score, 0.8±1.0) after CA for symptomatic paroxysmal AF and examined the details of late-phase TE. During a follow-up of 49.5±21.9 months (median, 47 months; range, 6-113 months) after CA, 9 patients (0.78%) developed late-phase TE, all of which were ischemic stroke. Of these, 5 patients with AF recurrence experienced cardioembolism; the AF was asymptomatic at recurrence. The remaining 4 without AF recurrence experienced cardioembolism (n=1), small-vessel occlusion (n=1), large-artery atherosclerosis (n=1), and stroke of other determined etiology (n=1). On


Kaplan-Meier analysis patients with structural heart disease (P=0.003), AF recurrence after the final CA (P=0.01), prior stroke (P=0.002), CHADS2score ≥2 (P=0.0002), left ventricular ejection fraction <50% (P<0.0001), and spontaneous echo contrast on transesophageal echocardiogram (P=0.0004) had a significantly higher risk of late-phase TE. Multivariate analysis indicated that CHADS2score ≥2 (HR, 4.49; 95% CI: 1.08-22.56; P=0.04) independently predicted late-phase TE. The incidence of TE was low after CA for paroxysmal AF, but CHADS2score ≥2 independently increased the risk of late-phase TE.layer 12 from over the top surface 11A of the insulating layer 11.
f) Now, we electrolessly plate Cu over the seeding film 13 forming a copper fill 16 (plug) filling the hole 14.
g) The copper fill 16 is chemical-mechanical polished to planarize the copper fill (copper plug) 16 to a level even with the top surface 11A of the insulating layer 11.
The second embodiment forms a Pd passivation cap 17B over the Cu fill 16 by a process involving the same steps as the first embodiment up to the electroless Plating of Cu. See FIGS. 2A-2C. The Second embodiment""s Cu fill 16 only partially fills the hole 14. Next, a key passivation layer composed of a combination of Pd/Pd acetate is formed on the Cu plug and at


make that deal appear at least a little less lopsided.

Briefly: Jay Witasick, who was designated for assignment nine days ago, is expected to sign with Tampa Bay today and the veteran right-hander said by phone he believes that it's a good fit for him. Witasick sought his release from the A's because he was looking for an opportunity to go to a team where he could contribute more. The A's will be responsible for the bulk of his $1.5 million salary. ... According to Lieppman, lefty Brad Halsey, who had shoulder discomfort in April, is following a throwing program and doing well with it. "He's on the right path," Lieppman said. "He's just going to go as far as he can go without surgery." Halsey's agent, Tom O'Connell,Q:

How to test a named_scope that references a class attribute with Shoulda?

I have the following ActiveRecord classes:
class User < ActiveRecord::Base
  cattr_accessor :current_user
  has_many :batch_records
end

class BatchRecord < ActiveRecord::Base
  belongs_to :user

  named_scope :current_user, lambda {
    { :conditions => { :user_id => User.current_user && User.current_user.id } }
  }
end

and I'm trying to test the named_scope :current_user using Shoulda but the following does not work.
class BatchRecordTest < ActiveSupport::TestCase
  setup do
    User.current_user = Factory(:user)
  end

  should_have_named_scope :current_user,
                          :conditions => { :assigned_to_id => User.current_user }
end

The reason it doesn't work is because the call to User.current_user in


for a person to be wrong about himself. It is quite another thing for him to be in disagreement with what God says about him. God says every man knows. Therefore, anyone who says he doesn’t know is calling God a liar. It’s a bit like a man arguing with his mother about what day he was born. Only in this case, it’s not his mother, but his inerrant, infallible, Creator.

Third, anyone who claims to be an atheist is ignoring his greatest need, and his only hope for its fulfillment. Man’s greatest and ultimate need is God. Apart from God, man is incomplete. Moreover, he is utterly incapable of achieving or attaining what he lacks. This is what drove Solomon to write, “Then I considered all that myhands had done and the toil I had expended in doing it, and behold, all was vanity and a striving after wind, and there was nothing to be gained under the sun” (Eccles. 2:11). This is the state of every person apart from God.

Man’s greatest and ultimate need is God.

1. People Know There Is a God

As we have already seen, Paul makes it very clear that people know God exists. However, they suppress that truth in their unrighteousness. Nevertheless, the knowledge is within them.

We see it in various ways in even the most ardent deniers of deity. (1) We see it in times of crisis, like the days following the tragedy of September 11, 2001, or December 7, 1941. (2) We see it in times of great joy,


Computer Systems Administration TE2003 Lecture overview At the end of lecture 9 students can identify, describe and discuss: Main factors while

Thanks for showing interest in Vortex IIT Delhi & What After College (WAC) Ethical Hacking Workshop. Our aim is to address the students apprehensions and anxieties regarding their career prospects in EthicalQ:

Problem with opamp stability in DC load

I'm trying to make DC load up to 20A with 1mA precision.
Current sense resistor is 5mΩ, so the voltage on this current sense will be from 5μV to 100mV.
I picked LTC2050HV (datasheet) which have very low input offset (±0.5μV).
This is my circuit:

First opamp (U4) just multiplies voltage on current sense (R21) by factor of 40, so Vout1 can be from 0.2mV to 4V. Second opamp (U2) compares this with voltage set by potentiometer (RV1) (it will be replaced DAC later) and controls power mosfet (Q6).
There is only one power mosfet IRF540N, I am about to add more parallel mosfets later. This is just a testing circuit.
Problem is that there are some oscillations and I'm not able to remove


/*==============================================================================
    Copyright (c) 2010 Christopher Schmidt

    Distributed under the Boost Software License, Version 1.0. (See accompanying
    file LICENSE_1_0.txt or copy at http://www.boost.org/LICENSE_1_0.txt)
==============================================================================*/

#ifndef BOOST_FUSION_INCLUDE_MAKE_UNFUSED_HPP
#define BOOST_FUSION_INCLUDE_MAKE_UNFUSED_HPP

#include <boost/fusion/support/config.hpp>
#include <boost/fusion/functional/generation/make_unfused.hpp>

#endif
These findings show that patients with both OSA and COPD have higher sympathetic modulation of heart rate compared with those with OSA or COPD alone. Furthermore, the findings provide a potential mechanism for the increased morbidity and mortality reported in patients suffering from both disorders, suggesting new therapeutic perspectives in Overlap syndrome.


at Tom Colicchio’s restaurant, Craft, for LA Restaurant Week. We had mixed reviews about our experience which I’ll detail in a Yelp review at some point.

On Sunday I went with some friends on a fun shopping adventure to the Renegade Craft Fair which featured over 250 indie crafters, make-n-takes and workshops, food trucks, popsicle stands, a dj, a beer garden, and amazing people watching. The Hot Trends right now are succulents, laser cut jewelry and stationery, repurposed and recycled items, more succulents, screen printed wearables and posters, all things knit and crochet, including crocheted cactus and succulents, ceramics and pottery, letterpress, and of course, more succulents!

I bought some delicious smelling soap from Padua Farms Bath & Body. It smells heavenly! Becky Morgan told me about her shop inAnge Postecoglou

Angelos "Ange" Postecoglou ( ; ) is a Greek-born Australian former football player and the former head coach of the Australia national football team. He is one of the most successful Australian club coaches with two premierships, four championships and a continental title. Currently, he is the manager of Yokohama F. Marinos.

Personal life
Postecoglou was born in Athens, Greece. After Postecoglou's father, Dimitris ("Jim"), lost his business following the 1967 Greek military coup, Postecoglou emigrated to Australia by boat in 1970 at the age of five, growing up in Melbourne, Victoria. In his early years he grew up playing Australian rules football and is a lifelong supporter of the Carlton Football Club in the Australian Football League. Postecoglou supports Liverpool.
Postecoglou is married to Georgia, who worked at South


League managers
Category:Yokohama F. Marinos managers
Category:2014 FIFA World Cup managers
Category:Sportspeople from Athens
Category:2015 AFC Asian Cup managers
Category:AFC Asian Cup-winning managers
Category:2017 FIFA Confederations Cup managers
Category:Melbourne Victory FC managers
Category:Association football defenders    ]
          }
        ]
      },
      {
        "id": 3,
        "name": "Processing",
        "groups": [
          {
            "groupName": "",
            "configurations": [
              {
                "id":


and convincing manifestations of the human spirit "

After exhibiting at the Stone Gallery in Newcastle, W.E. Johnson of the Manchester Guardian writes "In a pantheistic approach to nature, his stone and sea-shell compositions and a distinctive "Fantasie Sous Marine" have something of the metamorphic quality of the work of Graham Sutherland..." He also compares his work to that of Alan Davie, both he and Lanzi passing a sizeable portion of their war years as prisoners of war.

References

External links
 The official François Lanzi web-site at http://www.francoislanzi.com
 Paintings http://www.saatchi-gallery.co.uk/yourgallery/artist_profile/François+Lanzi/117150.html
 Painting "Nature Morte" https://web.archive.org/web/20110725014945/http://www.artnews.org/artist.php?i=6371
 http://www.artprice.com
 :fr:François Lanzi, peintre

Category:1916 births
Category:1988 deaths
Category:Abstract artists
Category:20th-century French painters
Category:French male painters
Category:Modern painters
Category:People from Ajaccio
Category:Collage artistsChristianity through the centuries is that we worship 3 Gods: the Father, Jesus, and the Holy Spirit. Do Christians believe in more than one God? No. Emphatically the Bible teaches that there is one God only. (See the diagram at right.)

· We believe in one God Who is Tri-Personal—in three persons.

· All three are one God; each is not the other. This is how God has revealed Himself in the Scriptures.

Jesus Christ is God in His eternal divine nature. Our passage today equates Jesus with God. Jesus Christ is truly and fully human, but without sin. The second person of our triune God took on a human nature and body when He was conceived by the Holy Spirit in the womb of Mary. So, what do Christians believe


is from the heart, not a task. Joyful servants willingly sacrifice and don’t whine about it. Ask yourself: How am I serving Jesus? Try some things out to see what’s a good fit. True Christian service is fun, for you. And, gives glory to Him.

Melanie Newton is an “everyday” kind of woman who has served her “ever faithful” God in whatever sphere He has placed her—family, church, homeschooling, MOPS. As a Louisiana girl who became Jesus’ disciple in college when introduced to His Word, her ministry passi... MoreAnita Hill Speaks To Essence About Sotomayor’s Nomination

Anita Hill will always be linked to the Senate confirmation hearings for the Supreme Court. In 1991, she gave an explosive testimony during the confirmation of Justice Clarence Thomas that forced a generation of women to stand up against sexual harassment. On the cusp of the Senate hearing for President Obama‘s Supreme Court nominee, Sonia Sotomayor, Hill, today a professor of law at Brandeis University, talked to ESSENCE.com about Sotomayor, a former classmate of hers at Yale Law School, and the legacy of her Senate Judiciary testimony all these years later.

ESSENCE.COM: What do you think of Sonia Sotomayor as a Supreme Court nominee?
ANITA HILL: I think it’s an excellent choice, just on the face of the selection. Here’s a person who


apparatus is disclosed that each processing target region is assigned to a plurality of CPUs at the stage of generating writing data to be input for electron beam writing to perform parallel processing independently (refer to, e.g., Japanese Unexamined Patent Publication No. 6-97058 (JP-A-6-97058)).
As mentioned above, in the electron beam pattern writing apparatus, writing data inputted is converted to internal format data of the pattern writing apparatus by using a plurality of processing devices in which processing is performed in parallel according to the specification of the pattern writing apparatus. If a conversion error occurs in a processing apparatus, to which a certain processing is assigned, in a plurality of processing apparatuses, it becomes impossible to write a desired pattern defined by the writing data. Then, if aDespite high rates of return to a community college education, only a small fraction of students who enroll persist to degree completion. Research has demonstrated that there are four primary reasons for this: tuition and associated costs, insufficient academic preparation, personal non-academic obstacles, and social and institutional obstacles. While survey evidence suggests that the latter two sets of impediments are important, current approaches have focused primarily on costs and academic issues. We propose to evaluate an innovative intervention, Stay the Course, that builds on the existing literature by focusing on the less-studied barriers. Stay the Course assists low-income students in dealing with personal and social barriers to educational attainment in two ways: comprehensive case management and emergency financial assistance (EFA). Case management includes holistic, wrap-around counseling designed to


At the beginning of January, the CyanogenMod team started rolling out the official CM12 nightlies for a wide range of devices. CyanogenMod 12 is based on the very latest version of Android — Lollipop — and is the biggest update that the OS has ever received ever since its inception.

With Lollipop, Google has given Android a major visual overhaul leaving no single area untouched. In addition, the OS also comes with many useful features like Smart Lock, lockscreen notifications, Ambient display and more.

Most OEMs are yet to roll out the Lollipop update for their devices, and when they will, the new Material Design introduced by Google will be overshadowed by their own skin. Thus, CyanogenMod 12 is the only way for many to experience the stock goodness of(due to replacing the square with i*i and j*j. If you do not replace the squares, the performance is equal to np.sqrt(i**2+j**2).
Some timings using single floats:
i = 23.7
j = 7.5e7
%timeit np.sqrt(i**2 + j**2)
# 1.63 µs ± 15.6 ns per loop (mean ± std. dev. of 7 runs, 1000000 loops each)
%timeit (i*i + j*j)**0.5
# 336 ns ± 7.38 ns per loop (mean ± std. dev. of 7 runs, 1000000 loops each)
%timeit math.sqrt(i*i + j*j)
# 321 ns ± 8.21 ns per loop (mean ± std. dev. of 7 runs, 1000000 loops each)

math.sqrt is slightly faster than (i*i + j*j)**0.5, but this comes at the cost of losing flexibility: (i*i + j*j)**0.5 will work on single floats AND arrays, whereas math.sqrt will only work on scalars.
And some timings for medium-sized arrays:
i


branching instructions. However, such prior art implementations require the filling of a branch target cache the first time an unexpected branch is encountered, resulting in overhead.
Accordingly, what is desired is a system and method that resolves the problem associated with the presence of decrement, test, and branch overhead by implementing ZOLs using an existing micro-architecture.Q:

How to Iterate through HashMap containing Arraylist

Can you send the implementation how to Iterate through HashMap containing ArrayList, here is my code, I created 2 ArrayLists and added to Hashmap and I need to iterate through
public class t {

public static void main(String[] args) {

    ArrayList<String> a = new ArrayList<String>();
    ArrayList<String> b = new ArrayList<String>();

    a.add("a");
    a.add("b");
    a.add("c");

    b.add("d");
    b.add("e");
    b.add("r");

    HashMap<String, ArrayList<String>> hm = new HashMap<String, ArrayList<String>>();

    hm.put("Tomek", a);
    hm.put("KOT", b);

    for (Entry<String, ArrayList<String> m : hm.entrySet()) {

        // code to type....


# Episode 24

[Video](https://www.youtube.com/watch?v=-rNCfZyDzNw&list=PLRAdsfhKI4OWNOSfS7EUu5GRAVmze1t2y&index=25) |
[Pull Request](https://github.com/terrajobst/minsk/pull/142) |
[Previous](episode-23.md) |
[Next](episode-25.md)

## Completed items

* Add trivia, which allows storing whitespace and comments in the syntax tree
* Add classification, which performs syntax highlighting by using the syntax
  tree

## Interesting aspects

### Syntax tree as the source of truth (pun intended)

Most text book compilers use [abstract syntax trees (AST)][ast] to represent the
source code. They are deliberately not a truthful representation (hence the term
*abstract*). For example, they won't contain whitespace nor comments. Often,
they also don't contain things like parenthesized expressions as the grouping is
evident by the structure of the tree already. Usually, the semantic analysis
doesn't produce a new tree but will instead fill in things like type information
into the nodes directly. In some compilers lowering (or de-sugaring) will also
happen during parsing or binding.

This design makes sensetoken.

Having both leading & trailing trivia allows us to associate them with the token
that makes more sense for the developer:

* If a comment is on a line by itself, it usually refers to the following code.
* If a comment is on a line with code, it usually refers to the code before it.

Let's look at a few examples:

```JS
// Comment 1
function Foo(a: int, // Comment 2
             b: int) // Comment 3
{
    let x = a /* Comment 4 */ + /* Comment 5 */ b
    /* Comment 6 */ let y = x // Comment 7
    // Comment 8
}
```

According to the rules stated above the comments are associated


}
    public Classification Classification { get; }
}
public static class Classifier
{
    public static ImmutableArray<ClassifiedSpan> Classify(SyntaxTree syntaxTree, TextSpan span);
}
```

The classifier will only return spans that are contained in the provided span.
Tokens that are overlapping with the provide span's start or end are clipped to
fall within the span. And since the syntax is in tree form we can even leverage
the node's `FullSpan` property to only visit nodes that are overlapping with the
provided span.

This makes it really easy to do perform [line-based syntax highlighting in the
REPL][highlighting]:

```C#
var classifiedSpans = Classifier.Classify(syntaxTree, lineSpan);

foreach (var classifiedSpan in classifiedSpans)
{
    var classifiedText = syntaxTree.Text.ToString(classifiedSpan.Span);

    switch (classifiedSpan.Classification)
    {
        // Set foreground color based on classification
  Q:

WPF How to set Validation.HasError property on controls manually?

I have a wpf window which fires validation when a user interacts with the control (got into the control and change the value which results in updated property) and upon property changed, validation fire and displayed as it should.
But I want to show all validation errors on the screen manually when a user clicks on the save button without traversing the controls, otherwise how it suppose to look if the user loads the screen and click on the save button.
Even if I create a method like IsValid() and call it upon clicking on the save button, it validates the whole form and tell me if it is valid or not but the red border around text boxes won't be showing(because


Axillary node interventions in breast cancer: a systematic review.
Recent data from clinical trials have challenged traditional thinking about axillary surgery in patients with breast cancer. To summarize evidence regarding the role of axillary interventions (surgical and nonsurgical) in breast cancer treatment and to review the association of these axillary interventions with recurrence of axillary node metastases, mortality, and morbidity outcomes in patients with breast cancer. Ovid MEDLINE (1946-July 2013), Cochrane Database of Systematic Reviews (2005-July 2013), Cochrane Database of Abstracts of Reviews of Effects (1994-July 2013), and Cochrane Central Register of Controlled Trials (1989-July 2013) were searched for publications on axillary interventions in breast cancer. Clinical trials, observational studies, and meta-analyses with at least 2-year follow-up were included. A total of 1070 publications were reviewed, 17 of whichNow Available - Armada 2526 Gold

Lead one of 18 different alien races to become a mighty pan-galactic empire. Manage your colonies, deploy your fleets and conduct research. Plot your strategy and turn your planets into mighty bastions. Explore new star systems, where you may encounter tachyon storms, psychic plants, primitives or find abandoned alien technology. Diplomacy is of utter importance in being successful. Make pacts and alliances, make threats or ask for favours - and when the time is right, replace diplomacy by space combat and fight it out in real-time 3D.

*Offer ends March 7th at 10AM Pacific Time.

There is also a special loyalty discount for owners of Armada 2526. Please login to Steam and check the store page for details.


Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.
It has been well known that curcumin is a powerful inhibitor of proliferation of several tumor cells. However, the molecular basis of the anti-proliferative effect of curcumin has not been investigated in detail. In this paper, we present evidence to show that curcumin inhibited proliferation of a variety of B lymphoma cells. At low concentrations curcumin inhibited the proliferation of BKS-2, an immature B cell lymphoma, more effectively than that of normal B lymphocytes and caused the apoptosis of BKS-2 cells in a dose- and time-dependent manner. Furthermore, curcumin downregulated the expression of survival genes egr-1, c-myc, and bcl-X(L) as well as the tumor suppressor gene p53 inThe effect of ethanol on prolactin release from pituitary cells in vitro.
Exposure to ethanol is recognized to cause reproductive impairment in man and animals. Since elevated levels of prolactin will interfere with normal functioning of the hypothalamic-pituitary-gonadal axis, and since ethanol has been shown by others to lead to increased prolactin secretion in vivo, the present in vitro study was undertaken to determine whether there is a direct effect of ethanol (ETOH) on prolactin release. Prolactin release from anterior pituitary cells maintained in monolayer culture and exposed to either no ethanol or media containing ethanol at concentrations of 50, 100, 200, or 400 mg% was measured at 1, 4, 24, 48, 72 hours in incubation. Ethanol added directly to pituitary cells stimulated prolactin release at all time points


in mainland Europe as a Brexit barometer. An indication as to how likely - or not- it might be that Britain will choose to exit the EU.

The majority of Britain's EU partners want it to stay and so - as an article in France's influential Le Monde put it last weekend - Brussels has been treading carefully these last weeks not to focus on issues that might "annoy" the UK.

Hence the reluctance to discuss this week's election in too much detail.

While Europe has barely featured in the election campaigns in Britain - with the exception of Ukip which managed to link the issues of the EU and immigration - here in Brussels the UK vote is being scrutinised to an unprecedented extent.

David Cameron has promised to hold areferendum on Britain's membership of the EU by 2017 if the Conservative Party is returned to government. Labour hasn't ruled out a referendum at some point and many EU civil servants believe the public mistrust of Brussels to be so high in Britain, they assume there'll be a demand for some kind of EU vote.

image copyright Reuters image caption Angela Merkel has said she wants the UK to remain in the EU

But the tone surrounding a possible referendum and its timing is thought here to depend very much on which party or parties form the next British government.

"Europe is watching," Sophie in 't Veld, vice-chair of the Alliance of Liberals and Democrats for Europe, told me.

"People here realise that national elections have implications for the course of the


  }
});
mainVideo.setOnErrorListener(new MediaPlayer.OnErrorListener() {
    @Override
    public boolean onError(MediaPlayer mp, int what, int extra) {
        showErrorMessage(R.string.multimedia_load_failed, R.string.please_try_again_later);
        parent.hideLoader();
        return true;
    }
});
Uri video = Uri.parse(mm.url);
mainVideo.setMediaController(new MediaController(parent));
mainVideo.setKeepScreenOn(true);
mainVideo.bringToFront();
mainVideo.setDrawingCacheEnabled(true);
mainVideo.setActivated(true);
mainVideo.setEnabled(true);
mainVideo.setVideoURI(video);

Log.i(TAG, "Loading video: " + video.toString());

(parent is a reference to the activity that has some convenience functions like showLoader and whatnot.)
Here is my layout:
<?xml version="1.0" encoding="utf-8"?>
<ScrollView xmlns:android="http://schemas.android.com/apk/res/android"
    android:layout_width="match_parent"
    android:layout_height="match_parent" >
    <LinearLayout
        android:layout_width="match_parent"
        android:layout_height="wrap_content"
        android:orientation="vertical">

        <FrameLayout
   android:layout_height="110dp"
            android:layout_width="wrap_content">
            <LinearLayout
                android:id="@+id/mm_media_list"
                android:layout_height="match_parent"
                android:layout_width="wrap_content">
                <!-- Content filled dynamically -->
            </LinearLayout>
        </HorizontalScrollView>
    </LinearLayout>
</ScrollView>

I have looked all over StackOverflow and around


Award for Best Supporting Actor.

The following year he starred in a satire of the US military, Buffalo Soldiers (2001). Phoenix starred opposite Mel Gibson in the science fiction thriller Signs (2002), a massive commercial success. He starred in the romance-drama It's All About Love (2003) and voiced Kenai in the animated film Brother Bear. In 2004, Phoenix starred as a farmer in the psychological thriller The Village and as a Baltimore firefighter in the drama Ladder 49. He followed this with a supporting role in the historical drama film Hotel Rwanda (2004). Phoenix portrayed musician Johnny Cash in the biopic Walk the Line (2005) opposite Reese Witherspoon. Phoenix played and sang all of Cash's vocal tracks in the film and on the accompanying soundtrack. This earned him the[Coercive Measures in Child and Adolescent Psychiatry in Post-war Germany, Using the Example of the "Pflege- und Beobachtungsstation" in the State Psychiatric Hospital Weissenau (1951-1966)].
Coercive Measures in Child and Adolescent Psychiatry in Post-war Germany, Using the Example of the "Pflege- und Beobachtungsstation" in the State Psychiatric Hospital Weissenau (1951-1966) The patient admissions at the children's ward of the State Psychiatric Hospital Weissenau in the years 1951, 1956, 1961 and 1966 were analyzed regarding documented coercive measures. Shortage of staff, mainly inadequately skilled personnel, a mixing of age groups in the patient cohort, neurological and psychiatric disorders and of patients who were in need of nursing and of those who needed treatment constituted the general work environment. Coercive measures against patients, mostly disproportionate isolations, were a constant part of


Anatomic Therapy

126. SAMAADHI

If we are not thinking about anything for a very short duration such as one or two minutes, this state is called Dhyaanam. If we are in Dhyaanam for a long duration such as one or two hours, then this state is called Samaadhi.

Thus, Yoga consists of these eight parts. Our Anatomic Therapy treatment is nothing but the first two parts of yoga. Please do not see Anatomic Therapy and yoga as two separate things. If you have understood the first two parts of yoga, you have understood Anatomic Therapy. The first two parts of yoga deal with what we should not do and what we should do.

Thus, Anatomic Therapy and Yoga are not different from each other. In all yoga centres, straightaway they teach youOn June 19, police said White and another man they have not arrested yet went to Blackmon’s house. When they came out of her house, they were armed, and fired 15 shots into the house across the street, police said.


and depend on.
The only thing I watch is my protein intake at meals. Never more than 2 eggs at breakfast,,,, and never more than 3 or 4 ounces of protein at dinner.
Protein is ALWAYS overshadowed by a TON of veg on the plate LOL
Lunch is usually always my homemade ranch style beans made from scratch…. with lots of hot peppers and beef bones for flavor… slow cooked in my crock pot for 8 hours. lol
but never more than 3 tablespoons at a time. I just dont feel I need to eat large quanities of them to be satisfied.
Dr. Davis…. i discovered all this on my own but YOUR BOOK states EXACTLY what I discovered because i was SO scared i was going to become diabetic.
As long as youwheat” argument, which is colossally bad advice!

btw here’s a great wheat belly recipe for salad – a girlfriend of mine made it the other day and its absolutely delish!!! I didn’t get the exact measurements but this is what she used:
mixed greens, chopped strawberries, chopped green apple, goat cheese, pecans, avocado and the dressing was a red vinegar, olive oil, maple syrup mix

Ri:
I believe there are so many out there who are ready to sabotage the efforts and successes of those of us who have given up wheat (and grains/sugar) because of their own unwillingness to do so. I just spent a weekend away with a friend who has been complimenting me on my weight loss for a year now. I keep telling her to ditch the wheat


issues, this blog would not exist. Nor would the many clean food products (pastured meats and eggs/dairy) or even the high glycemic gluten free products be readily available.

Few of us here would ever go back to the foods that made us sick in the first place.
It is important for you to keep in mind that it is not your concern about what friends and family (adults) choose to place in their mouths. It is only your concern about the food you place in your mouth. Only when they get sick or tired will they try to find a way to change their dietary habits. It is their choice and their bodies. You are happy with your choices. Respect theirs.

Barbara in New Jersey, I’m trying to turn over aAbstract

It is widely accepted that employee involvement and participation (EIP) is a key component of the high commitment bundle of HRM, but that it can take a range of forms in practice. Much of the analysis to date has either treated different forms of EIP as a single construct or has measured EIP by virtue of its presence or absence alone. Drawing on earlier work based on the data from WERS1998 examining the link between various forms of EIP and employee outcomes such as job satisfaction and organisational commitment, the authors re-apply and extend these ideas to data from WERS2004. In particular they develop the concept of institutional embeddedness, in order argue that both the depth and breadth of EIP have important associations with commitment though not with


It is, just not in the forums. Then again consider also the problem that tickets sell out so fast -- bc they're holding out -- so we would've also had a better turnout otherwise. From what I gather, Prime and East are the two biggest for dtoid meetups.

Yeah, PAX Prime attendance from Dtoiders was very weak this year Of all the friends I talked to, it was 100% because they couldn't get tickets or couldn't afford it. Hoping next year people will have better luck.

I apologize in advance as I wrecked the photo's while drinking and gaming Sat night and I did not have any back ups for Sunday photos so it was one day only I was also hesitant to ask people with props to hold thepictures as some people gave me some weird looks when I asked them, lol.

I was surprised as I did not see a single Dtoid shirt/robot or anything all day Sat and Sun and no one approached me as I had my dtoid shirt on.

Helmet was only present on Friday and Sunday because MuddBstrd and I were the only two who signed up to wear it. I was going to do it again on Monday, but then I remembered I had to leave early to catch the train so we just canned it. Hopefully next year we can have more people show up and volunteer.

Helmet was only present on Friday and Sunday because MuddBstrd and I were the only two who signed up to wear it. I was going


and parent.frame refer to the context of the
  parent interpreted function. So internal functions (which may or may
  not set contexts and so may or may not appear on the call stack) may
  not be counted, and S3 methods can also do surprising things.

A quick fix for your function is the set the data into the lm object to avoid the eval call:
fcast <- function(a,b,df,h) {
  model <- paste(a,'~',b)
  x <- ts(data=df)
  train.end <- time(x)[nrow(x)-h]
  test.start <- time(x)[nrow(x)-h+1]
  train <- window(x,end=train.end)
  test <- window(x,start=test.start)
  fit <- lm(model, data=train)
  fit$data <- train
  my.fcast <- forecast(fit,test)
}

A:

In addition to @James' answer. Your model is not properly defined. The argument model <- paste(a,'~',b) puts a ~ between allBenway that he should pay to Virgia Benway the sum of $25 per month until the further order of the court, and that to secure the first ten payments he should deposit the sum of $250 with the clerk of the court. It was further agreed that Mrs. Benway should have the custody of four of the minor children then in her custody, but that should she become unable to support them the three minor boys might be turned over to Benway, at his expense, but that, in such event, the rights of Mrs. Benway to the $25 per month should not be prejudiced. On the same day Benway deposited $250 with the clerk of the court, together with written instructions to the clerk that pursuant to an


the court has the power to correct such error; and as to what constitutes a clerical error within such rule is stated, page 715, that while in its original and literal significance, a clerical error is one made by a clerk or some subordinate agent, latterly the meaning has been broadened and extended so that now it may include an error that may have been made by the judge or court. It also said, page 717, that as to such clerical errors, when same are apparent upon the face of the record, no time limit exists as far as the right to make the correction is concerned, and that the trial court has full power to determine whether the error was clerical or judicial in character, citing Harmandecision, and that in so acting he is exercising one of the functions of his judicial office, citing Kaufman v. Shain, supra, and Kowalsky v. Nicholson, 23 Cal.App. 160 [137 P. 607]. It also quoted from Livesay v. Deibert, 3 Cal.App.2d 140, 147 [39 P.2d 466], where the court said that it was for the trial judge to determine whether the order was all that he intended it to be; that if the mistake was clerical it could be corrected; that it must be presumed that he found it to be his own clerical error; that the facts were within his knowledge and that he had a right to rely upon his own memory; and that the court retained jurisdiction to amend the original order to correct clerical


inherited by Famous Tuboranon Leaders. They were appointed and elected based on our Tubod Municipal Archives record. Tubod was previously part of the Municipality of Mainit, Surigao del Norte. It created by virtue of Executive Order No. 269 dated September 18, 1957.

Demographics

The Surigaonon language is the common local language, while Cebuano, Filipino, and English are also spoken.

Climate

See also
 Lake Mainit Development Alliance

References

External links

 Municipal Website Blog of Tubod
 Philippine Standard Geographic Code
 Philippine Census Information
 Local Governance Performance Management System

Category:Municipalities of Surigao del Norte4*c. What is the greatest common divisor of c and 6?
3
Suppose -3*f = -2*s - 6, 0 = 5*f - 3*s - 6 - 5. Suppose 35 = 2*c - o, -c + 3*o + 6 = -f. What is the highest common divisor of 209 and c?
19
Suppose 5*r - 700 - 315 = -5*g, 0 = -2*g - 3*r + 411. Calculate the greatest common factor of g and 22.
22
Let b be -2 - 0 - (0 - 0). Let p be 6/3*(-4)/b. Suppose 5*l - 5*r = -p*r + 114, 4*l = -3*r + 76. What is the greatest common factor of 55 and l?
11
Let w = 109 - 8. Suppose l - 39 = -3*p, 0 = 3*l + l + p - w. Calculate


the greatest common divisor of 168 and l.
24
Suppose -4*a = -7*a + 144. Suppose -389*y + 384*y = -120. Calculate the greatest common divisor of a and y.
24
Let n(f) = -2*f + 1. Let v = -9 + 8. Let g be n(v). Suppose -23 = -g*k - y, -5*y + 3*y + 28 = 3*k. Calculate the highest common factor of k and 2.
2
Let m(w) = -35*w + 2. Let a be m(-2). What is the highest common factor of a and 18?
18
Suppose -3*q - 2*d + 24 - 2 = 0, 3*d = -q + 12. What is the highest common divisor of q and 15?
3
Suppose -409 = -5*o - 2*z + 379, -z = -5*o + 791. Let d = o + -108. Let sWould it be okay if I painted this? I would give you complete and total credit, it's for a school assignment, we have to do one big major project due by the end of the year and I just really fell in love with this. Please let me know. (:


is no question but that we may elect to take jurisdiction over this appeal even though there never was a separate Rule 58 judgment.   In Banker's Trust Co. v. Mallis,5 the Supreme Court held that a circuit court has jurisdiction over an appeal from an order of dismissal when the order was "the final decision in the case" and the appellee "did not object to the taking of the appeal in the absence of a judgment."6  In this case, Houston has not objected to the omission of a Rule 58 judgment, and has thus waived its right to do so.   And the district court's order dismissing Whitaker's complaint clearly constituted a final judgement for purposes of 28 U.S.C. § 1291 as it endedthe limitations period has expired.   In any such case, dismissal of the complaint terminates the action even though the district court does not use those precise words, and thus constitutes a final order, subject to the thirty-day appeal limit--assuming, that is, that a Rule 58 judgment was entered, which was not the case here.   If, on the other hand, the district court's order does not expressly or by clear implication dismiss the action, then under Czeremcha, such order merely dismisses the complaint.   In that case, the plaintiff may amend under Rule 15(a), but only with permission of the court.   After dismissal, the plaintiff does not have the right to amend as a matter of course.18

18
As no Rule 58 judgment was


that works. In small
  programs there's really no problem, but in large programs this problem
  of excessive coupling is very serious. Coupling occurs when one part
  depends on the specific implementation of another. The more coupling
  there is the more costly it becomes to make changes because too much
  code depends on specific implementations. This causes software rot - a
  program becomes progressively less usable because it can't be easily
  upgraded.

So, increasing visibility is actually not a good idea. Such code could couse trouble in future development and maintenance.

A:

One reason to do this is if you have a method you need to override elsewhere in your project and the current scope does not allow you to. Typically when using default insteadexample, where found to strongly depend on the sample preparation procedure and thus its microstructure [@Atman_2005]. However, systematic investigations of the mechanical properties as a function of the microstructure are scarce, for two reasons: first, a systematic study of the microstructure-dependent mechanical properties requires the possibility of an unambiguous characterization of the microstructural arrangement of the particles. Second, and equally important, it relies on the possibility of a reproducible generation of microstructures with distinct local arrangements of the particles at constant volume fraction.

In [@Schenker_pre_2009], the concept of the degree of heterogeneity (DOH) has been introduced, constituting a scalar measure of the heterogeneity of the microstructural arrangement of a sphere packing. Three distinct structure characterization methods in conjunction with parameters in fit functions or integrals were shown to allow for a


as a unique set is used for all structures.*

Initial Microstructures
-----------------------

Two sets of microstructures are used as initial particle configurations for the simulation of the elastic properties. A first set originates from previous Brownian dynamics (BD) simulations [@Huetter_2000; @Huetter_1999] where the coagulation of electrostatically stabilized colloidal suspensions to stiff particle structures was simulated. The presence and depth of a secondary minimum in the inter-particle potential, described by the Derjaguin-Landau-Verwey-Overbeek theory [@Russel_1989], was shown to account for the variations in the DOH of the resulting particle structures and is adjusted via the surface potential $\Psi_0$. For $\Psi_0 =
0$ mV, the electrostatic double layer repulsion is zero and the inter-particle potential is only given by the attractive van der Waals potential. For the set of simulation parameters used in [@Huetter_2000; @Huetter_1999], a secondary minimum appears0.373 & 4.52 & $ 0.480 \pm 0.049 $\
& $\Psi_0$ = 12 mV & 0.404 & 4.84 & $ 1.19 \pm 0.141 $\
& $\Psi_0$ = 13 mV & 0.410 & 4.75 & $ 1.05 \pm 0.124 $\
& $\Psi_0$ = 14 mV & 0.472 & 5.08 & $ 1.46 \pm 0.120 $\
& $\Psi_0$ = 15 mV & 0.536 & 4.97 & $ 1.62 \pm 0.213 $\

![Simulated plateau storage moduli $G'_p$ of the various microstructures ($\mathit{\Phi}$ = 0.4, $\mathit{r_0}$ = 0.25 $\mu$m) as a function of the DOH in terms of parameter $a$ and power law fit (solid line).[]{data-label="fig:fig6"}](fig6.eps){width="\linewidth"}

The solid line in Fig. \[fig:fig6\] represents a power law fit given by

$$G'_p \propto (a - a_0)^{\beta}, a \geq a_0,
 \label{eq:sim_plff}$$

with $a_0 = 0.373 \pm 0.001$ (shown as dashed line in Fig. \[fig:fig6\]) and $\beta = 0.187 \pm 0.032$.


absolute values of the experimental elastic moduli are reproduced, as shown in Fig. \[fig:fig5\]. In particular, the ratio between the elastic moduli of the heterogeneous and the homogeneous microstructures is in good agreement with the experimental value. This latter result is particularly remarkable, since the $G'_p$-ratio has not been subject of any calibration but reflects the influence of the microstructures and emphasizes the strong influence of the DOH independently of the interaction potential. Indeed, the model used in this study constitutes an important simplification with respect to theoretical models such as the Derjaguin-Landau-Verwey-Overbeek theory [@Russel_1989] or the Johnson-Kendall-Roberts theory [@Johnson_1971]. The former gives the inter-particle potential as the sum of the van der Waals attraction and the electrostatic repulsion and the latter describes the adhesive force between particles.

Using the calibrated model,the light less prominent, or you can increase it and make the light more prominent.

I'm not saying the picture is not worrying, but I would like to know to what degree I should be worried by it based on science rather than 'pretty
colours'.

Maybe your right about the pictures and all but the last graph stated nuclear pollution right?

You and I know that what is happening over there concerns the whole world , If you hear that large amounts of radioactive material is pouring into the
ocean everyday and if you know that ocean currents can reach speeds for about 4 knots and are connected to almost every ocean in the world. Not even
mention the studies that water has memory and how this could work out in the near future?

So


a nuclear explosion. The TEPCo have now officially called it
“detonation”. The hot fuel rods caused a rapid expansion of the water added (water vapor explosion). This caused the collapse of the water shield
between the fuel rods stored in the storing pool, and this may have caused a supercritical condition momentarily and, hence, led to a nuclear
explosion. The nuclear explosion was not very extensive, but there is a sign that it may have occurred at the storing pool. If this is, indeed,the
case, then not only fission products but also U-238. U-235, Pa-239, and neutrons would have been released. Pu-239 (and also other Pu isotopes) has
been detected around the plant and up to several tens of kilometers away. These data suggest the release of fuel rod material itself in additionto perpetuate the lineage of many currently inactive bombardment units with illustrious World War II records, Headquarters SAC received authority from Headquarters USAF to discontinue its Major Command controlled (MAJCON) strategic wings that were equipped with combat aircraft and to activate Air Force controlled (AFCON) units, which could carry on a lineage and history.

As a result, the 4137th was replaced by the 465 Bombardment Wing, and on 1 February 1963, the 781st, returning to its World War II designation of 781st Bombardment Squadron, took over the mission, personnel and equipment of the 342d Bombardment Squadron, which was simultaneously inactivated.  The squadron maintained half of its aircraft on fifteen minute nuclear alert and periodically flew Operation Chrome Dome missions.  and conducted strategic bombardment training operations to meet


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Driving Instructions:

Thornhill is located near the intersection of Hwy-404 and Hwy-407, approx. 20 km north of Toronto.From Hwy-407 Westbound: West on Hwy-407 to Bathurst St. exit 75.. South on Bathhurst to Clark Ave. East (left) on Clark to Garnet A. Williams Arena. Arena is on the right side of the road.From Hwy-407 Eastbound: East on Hwy-407 to Keele St. exit 69. South on Keele to Steeles Ave. East (left) on Steeles to Bathhurst St. North (left) on Bathurst to Clark Ave. East (right) on Clark to Garnet A. Williamswithdrew an original resolution to the UN Security Council that called for talks on status and submitted a resolution with EU-backing in September this year that simply called for dialogue.

Galharague explained that the EU has not formally linked Serbia’s recognition of Kosovo and its EU membership, but the reality of the situation is clear.

“‘There was no formal conditionality,’ Galharague said, adding that the Serbs now understand that to be a member of the EU they must eventually recognize Kosovo,” the cable reads.


Wine has to follow everything, even the quirks and often by trial and error (users submitting bugs for specific applications).
Nothing is guaranteed to run. Even things that work perfectly, even better than native, are not guaranteed to remain that way. Often in the Wine world, in order to fix something, you have to break half a dozen other things... You just hope you (or somebody else) finds those new bugs before the code hits a stable release.
If you want long term stable support for a batch of applications, look at the commercial arm of Wine: CrossOver.

This is certainly one way to increase the sales of EG tea.

How much EG do you use for a 6 to 8-oz cup?

Which brands of EG are full-bodied without needing large amounts of tea?

I like both upton’s egc and the tea merchant’s french earl grey quite a bit. I never use more than a slightly heaping teaspoon for either, in fact for the french EG, when I make iced tea I get quite a bit of mileage out of just the 1 teaspoon.


next time, having registered their protest.

There is pressure, too, for the PSOE and Sánchez. Despite sitting opposite an unpopular government, the party lost 20 seats. Rumours are already circulating that Sánchez’s leadership may be challenged by Susana Díaz, the PSOE’s premier in its Andalusian stronghold. It could be assumed that the PSOE’s electoral failure would play into Podemos’s hands but Pablo Iglesias’s refusal to abandon his promise of a binding referendum on Catalan independence will deter those for whom unity is important.

It is likely that a series of elections and leadership battles will ultimately produce a government. As Podemos’s Ghostbusters theme tune unwittingly predicted, there’s something strange going on – and nobody knows who they’re gonna call.governor he asked the legislature to call a Constitutional Convention without success. When the legislature later called a convention, Walsh won election as a delegate-at-large as part of a slate of candidates who endorsed adding provisions for initiative and referendum to the state constitution, key Progressive-era reforms. He served as a delegate-at-large to the Massachusetts Constitutional Convention in 1917 and 1918 that saw those reforms passed. His speech on behalf of initiative and referendum shows him in the role of populist and reformer:

There are men—and you and I know them—who, though proclaiming their belief in democracy, really are believers in autocracy. There are men within the knowledge of us all who believe in a government of the few, of the college bred class only, of those only who


and their descendants for generations to come."

When the Senate considered the Burke–Wadsworth Act to establish peacetime conscription for the first time in U.S. history, Walsh offered an amendment, which failed to pass, that would have delayed the law's effective date until war was declared. In June 1940, he authored an amendment to the naval appropriations bill, sometimes called the Walsh Act of 1940, which permitted "surplus military equipment" to be sold only if it was certified as useless for American defense. To aid Great Britain, the administration evaded the Walsh provision by substituting leases for sales and by trading equipment for bases. In 1941, when the administration used the Greer incident, an exchange of fire between a German submarine and an American destroyer, to authorize American forces towith imperialism and surrenders to power politics".

In 1945, demonstrating that his isolationism was not absolute, Walsh voted in favor of the United Nations Charter. He was one of a dozen senators who protested the failure of the United Nations to invite a Jewish delegation to its founding San Francisco Conference.

Given his poor relationship with the White House, Walsh anticipated that the administration might even support an opponent in a Democratic primary when he next ran for reelection. He faced no such challenge, but was defeated in his 1946 race for reelection by Henry Cabot Lodge Jr.

Personal life and death

Walsh was raised a Roman Catholic and throughout his life identified himself as a Catholic and practiced his religion both in public and in private. An altar boy as a


small groups not disrupting the session, such as members of Parliament from Telangana with their statehood demand or Nationalist Congress Party members seeking revocation of the ban on export of onions, the two sets who stalled proceedings on Wednesday.

On Wednesdayn Wednesday, reports that the Left parties, following their meeting with finance minister and leader of the Lok Sabha, Pranab Mukherjee, had compromised with the government on a price rise discussion proved incorrect.

Members of Parliament of the Left parties asserted there was no point in having a discussion on price rise without voting, unless the government took on board three issues that the Left defines as contributing to price rise.

“Left parties feel there is no point in another discussion on price rise. Already two discussions have taken place onthe projectiles. Studies have revealed that this munition is not desirable due to the duality of the design. Additionally, it has proven to be less effective with respect to the antipersonnel portion due to the lack of payload.
U.S. Pat. No. 4,515,083 issued to Anthony M. Caruso on May 7, 1985 relates to a fragmentation casing for a munition in which the size and distribution pattern of the shrapnel is controlled. This end is attained by means of a casing formed from a stacked array of rings in which angularly oriented inner and outer surface grooves form apertures at the mutual intersections. Through the control of ring size, groove depth and shape, a light weight efficient fragmentation casing is provided in which the size, shape and bursting pattern of


know you know we have a big silver dog named Beemer... wanna know how she came to be? I had never had a dog before and Josh wanted an inside one. I decided I wanted weim after working at the Birmingham Museum of Art during a William Wegman exhibit. She came from Tupelo, MS. We named her Beemer because I always said I wanted a silver BMW - Josh said this was the only one we could afford. I rescued her from the crate the very first night and she's been sleeping in our bed for six years.

I've been in several many car accidents. The first one was when I was fourteen and my boyfriend got sideswiped by a transfer truck. We didn't call our parents because wethe money on the table vastly outstrips the $100 million Vive X programme announced by HTC back in April, and potentially represents the largest investment in virtual reality technologies since Facebook's acquisition of Oculus VR.

Companies confirmed as members of the VRVCA include Sequoia Capital - a company which has frequently co-invested in technology concerns with Microsoft's venture capital arm - and CRU Capital, along with a number of VR-specific firms including HTC's freshly-minted Vive subsidiary itself. The group will meet every two months in Beijing and San Francisco and is currently asking for pitches via its official website.


*/
        }
        point--;
        tags--;
      }

      FT_TRACE5(( "  move to (%.2f, %.2f)\n",
                  v_start.x / 64.0, v_start.y / 64.0 ));
      error = func_interface->move_to( &v_start, user );
      if ( error )
        goto Exit;

      while ( point < limit )
      {
        point++;
        vec1.x / 64.0, vec1.y / 64.0,
                          vec2.x / 64.0, vec2.y / 64.0 ));
              error = func_interface->cubic_to( &vec1, &vec2, &vec, user );
              if ( error )
                goto Exit;
              continue;
            }


             numContours, anoutline );
  }

  /* documentation is in ftoutln.h */

  FT_EXPORT_DEF( FT_Error )
  FT_Outline_Check( FT_Outline*  outline )
  {
    if ( outline )
    {
      FT_Int  n_points   = outline->n_points;
      FT_Int  n_contours = outline->n_contours;
      FT_Int  end0, end;
      FT_Int  n;

      /* empty glyph? */
      if ( n_points == 0 && n_contours == 0 )
        return FT_Err_Ok;

      /* check pointthan ~160 degrees */
        if ( d > -0xF000L )
        {
          d = d + 0x10000L;

          /* shift components are aligned along lateral bisector */
          /* and directed according to the outline orientation.  */
          shift.x = in.y + out.y;
          shift.y = in.x + out.x;

          if ( orientation == FT_ORIENTATION_TRUETYPE )