_mappae mundi_ , world maps, that were produced under Catholic clerical guidance and sometimes put on public display within churches. These maps were usually centered on Jerusalem and depicted the entire known world (Europe, Asia and Africa). These wall maps were more than only geographical depictions. The famous Hereford _mappa mundi_ , for instance, produced around 1300 CE, also offers depictions of historical events in several places, most notably the biblical account of Genesis. As a result, the _mappae mundi_ were, in fact, combinations of geography and history. This genre was continued in book form after movable-type printing had been invented in 1450 CE by Johannes Gutenberg (1395–1468 CE) in Mainz, (now) Germany. A well-known example of such a combination of history and geography is the _Cosmographia_ bookthe meantime, the study of history had been virtually monopolized by universities, where it was – and still is – defined as the history of literate people, resulting in the exclusion of all other accounts of the past. Why would modern academia define history in such a way?

## A Very Short History of Academic History

The modern academic discipline of history emerged in the nineteenth century as part of the formation of nation states in Europe and the Americas. The first task of academic historians was to formulate a proud history of their own nation state (still known as 'patriotic history' in the Netherlands), which would provide a common identity to the inhabitants of these new social entities. In doing so, they followed in the footsteps of Roman historians


hard at the electrons, they find themselves more or less half-way between the atoms. As a result the bonded carbon atoms are not electrically charged. Such links are called covalent bonds. Carbon, hydrogen, oxygen, nitrogen, sulfur and phosphorus can all combine into molecules based on covalent bonds, although some of these bonds have an asymmetric, polarized character, because one atom is pulling harder at the shared electrons than the other. This polarization of charges is extremely important for building further complexity, because it makes possible a great many forms of weak electromagnetic attraction and repulsion among molecules, which over time has led to extremely large numbers of intricate shapes. The energy required to break covalent bonds is also in the range of about 1 eV.

The resulting molecules cansupports direct contact between modern and archaic humans.' Public Library of Science Biology _2_ ,11, e340.
  62. Reijnders, Lucas. 2006. 'Is increased energy utilization linked to greater cultural complexity? Energy utilization by Australian Aboriginals and traditional swidden agriculturalists.' Environmental Sciences _3_ , 3 (207–20).
  63. Roebroeks, Wil (ed.). 2007. Guts and Brains: An Integrative Approach to the Hominin Record. Amsterdam, Amsterdam University Press.
  64. Sherratt, A. 1996. 'Plate tectonics and imaginary prehistories: Structure and contingency in agricultural origins.' In: Harris, David R. (ed.) The Origins and Spread of Agriculture and Pastoralism in Eurasia. London, UCL Press (130–40).
  65. Sherratt, A. 1997. 'Climatic cycles and behavioural revolutions: The emergence of modern humans and the beginning of farming.' Antiquity _71_ , 272 (271–87).
  66. Simmons,


in particular, Alexander's elder brother, played a crucial role by helping to shape modern university cornerstone practices such as the emphasis on teaching and research, including PhD research. Wilhelm von Humboldt was one of the founders of Berlin University, now Humboldt University, where these new ideas were first put into practice. The rise of the middle classes all around the world in often relatively open democratic societies has led to the globalization of these pursuits.

* * *

## Industrialization: The Second Wave of Globalization

The rise of industrialization in the late eighteenth and early nineteenth centuries implied a fundamentally new way of producing complexity, namely with the aid of machines driven by fossil fuels that consisted of solar energy stored in bio-molecules that had accumulated in the Earth's crust over"Previously on  Grimm... (Henrietta) You now have access to a primal force of nature." "This is what I am now forever?" "There's nothing anyone can do to change that, Juliette." "I want you out." "[snarls]" "Bring it on, bitch." "[snarls]" "You almost killed Adalind." "There's something I have to show you." "[snarls] [snarls]" "You're not Juliette." "You're Adalind." "What did you do with her?" " Nick, it's me." " I don't believe you." "Listen, you... you proposed to me on this couch." "You had a ring." "I said no." "You hid it upstairs in the dresser drawer." "I found it." "Adalind would never know that." "How did this happen?" "I don't know." "I didn't know what was happening at first." "I was really nauseous." "I thought I


"Your mom needs to lighten up." "She's just paranoid something's gonna happen to us, that's all." "Well, she's right." "Something is gonna happen." "I brought us a blanket and a pretty candle to get you in the mood." " What was that?" " Nothing." "Relax." "[crunch]" "I think somebody's out there." "It's probably my mom looking for me." "What?" "Now?" "I need to go." "Go." "Hey, hey, hey." "I love you." "Now text me as soon as you're home, okay?" "Okay." "[accordion playing]" "♪ ♪" "[accordion stops] [accordion thuds]" "Hello, lad." "Oh, my God." "No." "[snarls] [squeals] [whimpering]" "[groaning]" "Aah!" "No, no, no, no!" "[roars]" "Aah!" "Peter." "No." " Mom?" " Stay inside." "Lock the door behind me." "[door locks]" "Peter?" "Peter?" "Peter?" "Oh, my God!" "Oh, no,"Throw it here." "It's all there." "We've been trying for so long." "[scoffs]" "You're sure this will work?" "It always does." "Thank you." "Thank you." "[playing slow tune]" "♪ ♪" "I love you." "I love you too." "Let's start a family." "Hm." "Not gonna kill you." "I got home late." "I didn't want to wake you." "Yeah, I'm sure it had nothing to do with me being a..." " I want to talk to Henrietta." " I'll call her." "I want to talk to her face-to-face." "I should go with you." "I think it'd be best if I went alone." "Okay." "I'll let her know you're coming." "This is the address." "You should really memorize it." "It can be a little bit tricky." "It's not me, I didn't


Q:

idw() or krige() Error: dimensions do not match when missing values

Functions idw() and krige() from gstat package keep reporting errors when either response or predictor variable contains missing values (NA), even when na.action is set to na.omit:
require(gstat)
data(meuse)
coordinates(meuse) = ~x+y
data(meuse.grid)
gridded(meuse.grid) = ~x+y

meuse2 <- as.data.frame(meuse)
meuse2[1, 'zinc'] <- NA
meuse2 <- SpatialPointsDataFrame(SpatialPoints(meuse), meuse2)

# idw response var
int <- idw(zinc ~ 1, meuse2, meuse.grid, na.action = na.omit)
# Error: dimensions do not match: locations 310 and data 154

# krige response var
m <- vgm(.59, "Sph", 874, .04)
int <- krige(zinc ~ 1, meuse2, meuse.grid, model = m, na.action = na.omit)
# Error: dimensions do not match: locations 310 and data 154

# krige predictor var
meuse3 <- as.data.frame(meuse)
meuse3[1, 'dist'] <- NA
meuse3 <- SpatialPointsDataFrame(SpatialPoints(meuse), meuse3)
int <- krige(zinc ~ dist, meuse3, meuse.grid, model = m, na.action = na.omit)
# Error: dimensions do notthe second half Monday night, forcing coach Mike Krzyzewski to give them a seat. The Badgers were leading 48-39 at that point.

Good thing the Blue Devils had another, far less-heralded freshman to bail them out.

Grayson Allen, who averages just four points per game, knocked down a big 3-pointer right in front of his own bench. Then he stripped the Badgers' Traevon Jackson of the ball at the other end, and added a three-point play moments later. Allen has 12 points in the title game. He had 12 in his previous three games.

The Badgers marching band has launched into ''Jump Around'' in Lucas Oil Stadium, but it will be Allen standing on the foul line for two more free throws when play resumes.

The Badgers are clinging to a 51-45


also evaluated short-term postoperative convalescence using the Convalescence and Recovery Evaluation (CARE) questionnaire. Our primary outcomes were HRQoL within 12 months and short-term convalescence within 6 weeks following cystectomy. We fit generalized estimating equation regression models to estimate longitudinal changes in BCI scores within domains, and CARE domain score differences were tested with Wilcoxon rank-sum tests. Results Clinical characteristics and baseline BCI/CARE scores were similar between the 2 groups (all P > .05). Within 1 year after surgery, recovery of HRQoL across all BCI domains was comparable, with scores nearly returning to baseline at 1 year for all patients. CARE scores at 4 weeks revealed that patients treated with ORC had better pain (29.1 vs 20.0, P = .02) domain scores compared to RARC. These differences abated by153 (V, 9), 360 (Appendix A, III).
http://tolkien.cro.net/dwarves/women.html

A:

The movie is not expected to be seen only by LOTR fans and former readers. Probably there are thousands (if not millions) of possible spectators that won't have even known that female dwarves had beards, even after Aragorn's joke in "The Two Towers".
This means that representing bearded female dwarves in the movie would probably make them pass undetected by many viewers, and would surely create uncomfortable questions for many others.
It is more than probable that the use of a "more traditional female aspect" on dwarven females was a production mandate to fulfill the political correctness that's expected from a family movie. And I'm quite convinced of it after seeing that not all dwarves in the movie had "dwarven facial traits". You


to control it from a distance. It was illegal to own or use thought makers within the Ferengi Alliance. Nevertheless, in 2364 DaiMon Bok used a thought maker in an attempt to discredit and ultimately kill Captain Picard. Purchasing the thought maker cost Bok his entire life's profit.21

An ancient Klingon knife which dates back to the time of Kahless, and is believed to be stained with his blood. The Knife of Kirom is held on the Klingon homeworld in a sacred vault, from which nobody is allowed to remove it. Nevertheless, it was removed by Gowron in 2369 and taken to Boreth. Gowron hoped to compare the DNA on the blade to that of the recently resurrected Kahless, to prove that he was a fraud. In fact, theMitogenic responses of rat nasal epithelium to hexamethylphosphoramide inhalation exposure.
Hexamethylphosphoramide (HMPA) is a rat nasal carcinogen that induces squamous cell carcinomas in the anterior portions of the nasal cavity following chronic inhalation exposures as low as 50 ppb. These tumors may arise as a result of P-450-mediated release of formaldehyde (HCHO), a known rat nasal carcinogen. The goal of this research was to investigate early responses of the nasal epithelium to inhaled HMPA. Rats were exposed nose-only to approximately 3 ppm HMPA for 6 h, and killed 18, 48, 96 or 144 h post-exposure. In a separate study, rats were exposed nose-only for 6 h for 1, 2, 3, or 5 consecutive days and killed 18 or 96 h post-exposure. With both single and repeated doses of HMPA,


({ \
	charon->bus->set_sa(charon->bus, sa); \
	sa->method(sa, ##__VA_ARGS__); \
	charon->bus->set_sa(charon->bus, NULL); \
})

/**
 * The one and only instance of the helper object.
 *
 * Set between exchange_test_helper_setup() and exchange_test_helper_teardown()
 * calls.
 */
extern exchange_test_helper_t *exchange_test_helper;

/**
 * Initialize charon and the helper object.
 *
 * @param plugins			plugins to load
 */
void exchange_test_helper_init(char *plugins);

/**
 * Deinitialize the helper object.
 */
void exchange_test_helper_deinit();

#endif /** EXCHANGE_TEST_HELPER_H_ @} */
a reasonable time as in other countries.

He said far from the Court tearing asunder the provisions of the Constitution by adjudicating on this application - as claimed by the State, it was the ongoing failure to call the by-election, which offended the terms and spirit of the Constitution and its framework for democratic representation.

The judge said he was not going to order the Government to move the writ or not to oppose a motion for the issue of a writ.

But he said he hoped any clarification provided by this judgment would have that effect.

Mr Justice Kearns said the court might feel constrained to take a more serious view if any Government, not just the present one, was seen to be acting in clear disregard of an applicant's constitutional


directly to agency heads, and often they do not control the budget of the IT organizations they oversee. Moreover, many agency CIOs play a minimal role in the selection or evaluation of IT leaders working in various component offices of the larger agency. The net result is that agency CIOs often lack control over or visibility into decisions for which, ultimately, they are held responsible.

How does this CIO revolving door affect agency IT operations and initiatives?

The cost in terms of morale and efficiency can be significant. Leadership changes in any organization can affect productivity. In the absence of strong leadership and clear objectives, employees begin worrying about job security, strategic initiatives lose momentum, and basically everything is put on hold until the new leader is in place. Whenof the response weighting function, *ρ*.

One can use the foregoing to predict the ratio of energy stored from the sinusoidal excitation to the energy stored from the source of noise. Thus the effective signal-to-noise ratio in terms of energy stored in the system is given by: $$S/N = \frac{2S_{i\rho}}{\pi n_{f}f_{0}}.$$

The signal-to-noise ratio will be a maximum if the frequency of the sinusoidal excitation is just equal to the natural undamped frequency of the system. (For this condition, *ρ = Q*~0~/2*π*.) The maximum ratio is: $$S_{0}/N = \frac{S_{i}Q_{0}}{\pi^{2}n_{f}f_{0}}.$$

The foregoing derivation has meaning also with respect to any system described by a second-order differential equation in which some event of brief duration occurs. A quantity directly analogous to the indication limit may be computed. In this instance, the expressions relate


\text{per}\ \text{radian}\ \text{fraction}\ \text{of}\ \text{the}\ \text{natural}\ \text{period}}} \\
{\quad = 2\pi\frac{\text{Peak}\ \text{energy}\ \text{stored}}{\text{Energy}\ \text{dissipated}\ \text{per}\ \text{cycle}\ \text{of}\ \text{the}\ \text{natural}\ \text{period}}} \\
{\quad = \omega_{0}\frac{\text{Peak}\ \text{energy}\ \text{stored}}{\text{Mean}\ \text{rate}\ \text{of}\ \text{power}\ \text{dissipation}}} \\
\end{array}$$

The second definition is commonly given because the amount of energy dissipated in a single cycle can be computed without finding a mean value. For our purposes, the third alternative gives the most direct approach to a generalized definition of *Q*.

The peak energy stored in the system under steady-state excitation is given by: $$E_{s} = \frac{A^{2}}{2D} \cdot \frac{M}{D} \cdot \frac{1}{{Q_{0}}^{2}{({1 - \phi^{2}})}^{2} + \phi^{2}}$$and the mean rate of power dissipation is $${\overline{W}}_{D} = \frac{A^{2}}{2D} \cdot \frac{\phi^{2}}{{Q_{0}}^{2}{({1 - \phi^{2}})}^{2} + \phi^{2}}.$$

The term ω~0~ in the third alternative of the definition for *Q*~0~ may be rewritten as 2π/*T*~0~, where *T*~0~ is theThe Dance April 21 2013, 1 Comment

The dance, my heart filled with joy and passion as I moved
through the room, every cell in my body was being awakened; I felt the
fluidness of my soul rush with pure bliss.I have fallen in love with 5 rhythms dance, it has brought such renewed
passion and ecstasy to me, it fills me and also gives me the foundation to be
available for all the other practices I have in my life, my body loves to
dance. Last night I deeply felt the tribe, I felt the connections of souls and
feet, I felt the power of being not alone, but with many other dancing beings,
I felt explosive, I felt expansive, I felt pure, I want this feeling in me all
the time, the dance is making


Additive Manufacturing consists of several processes that produce solid three dimensional (3D) objects from a computer model by building up the object in a layer-by-layer manner. Powder-based Additive Manufacturing processes use powders as the consumable materials, where the powders are deposited and then modified. For example, a layer of powder may be deposited and then modified by selected exposure to electromagnetic radiation, or selected deposition of liquid, which may be followed by exposure to electromagnetic radiation, or electron beam.
One example of a powder-based additive manufacturing process is the selective laser sintering process. In the selective laser sintering process a part is constructed one layer at a time inside a thermally controlled process chamber, which is held a temperature slightly below the melting point of the polymer system beingKaustine septic toilets which replaced the outhouse out back. The wide board in the back which served as a place for hooks for coats and such was replaced by hooks in the new entrance. The inside of the schoolhouse, though it was in near ruins for a long time, has been restored to something fairly representative of what it might have looked like for most of its history. Also, the space used to be heated by a box stove which sat on a brick foundation in the center of the room. This stove is no longer there. Prior to the 1930s, there was no electricity in the schoolhouse.

Renovation project
In 1995, restoration began under the guidance of the then president of the SAHS, Don Riddering. Particulars of the Restoration


of view, the key aspect of the project is that it is assessing cognitions about both the underlying goal of following prescribed treatment and about the specific behaviours such as taking medication as prescribed and exercise (Figure[1](#F1){ref-type="fig"}). From the methodological aspects, the novel elements are the consideration of both implicit and explicit cognitions, along with using objective measures of both exercise (attendance and clinically meaningful improvement in physical measures, such as improved fitness level, weight loss, improved circumferential anthropometric measures, improved one repetition maximum strength measures) and medication adherence (hair analysis).

![**Conceptual framework of medication and exercise adherence.** Light blue arrows represent the behavioural intention pathway (TPB). Goal intention models: dark blue arrows denote a pathway where goal intention is an antecedent; dark burgundy arrows show a pathway wherethe gap between behavioural intention and actual behaviour, Gollwitzer and Sheeran \[[@B59]\] proposed the addition of implementation intention.

Approaching behaviour from a different angle, the Control Theory \[[@B60]\] proposes that behavioural choices are driven by goal pursuits, where desired goals induce intentions but also serves as reference values against which the progress of achieving the goals are constantly monitored and adjusted if necessary. The allowance for incremental approaches to the desired goals connects goal theories of behaviour \[[@B57]\] and implementation intentions \[[@B59]\] via self-regulation by which people control their feelings and impulses to ensure behavioural outcomes that are perceived to be desirable. Self-regulation is a complex process that includes long-term perspectives in constant monitoring attainments \[[@B60]\] as well as resisting temptation with the view of pursuing long term goals


\[[@B65]\], reducing depression among people suffering from rheumatoid arthritis \[[@B66]\] and end-stage renal disease \[[@B67]\].

Self-regulation is present in peoples' daily lives because discrepancies between expectations and reality in situations people encounter are inevitable. Successful adaptive functioning is based on effective self-regulation by which people control their impulses, thoughts, feelings and adjust their behaviour to close or minimize the gap between their expectations and present experiences. The information processing models of self-regulation focuses on the process of constant comparison and feedback between the current and the desired, informing the necessary adjustment required to the behaviour \[[@B68]\]. However, the way people carry out this task is a reflection of their individual dispositions. General personality dimensions and specific self-referent personality traits are thought to be inseparably intertwined with self-regulation \[[@B69],[@B70]\]. Generalanti-HIV drugs in patients\' hair has been proposed \[[@B121],[@B122]\]. Methodologies have already been developed for detecting the presence of nevirapine \[[@B123]\], efavirenz, lopinavir and ritonavir \[[@B124]\] and lopinavir/ritonavir and atazanavir in hair \[[@B125]\] using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In this project, hair analysis is planned to test for the presence of the key anti-viral drugs, including new method development for tenofovir and abacavir in hair, to verify self-reports on adherence or non-adherence. As indirect outcome measures, clinically meaningful improvement \[[@B126],[@B127]\] is expected in fitness, circumference measures and perceived quality of life.

Research question
-----------------

Although a high level of adherence is required to benefit from prescribed medication and exercise programmes, in clinical practice adherence occurs on a continuum and often falls below the desirable level. Therefore, the


nine tests consists of 48 trials in 2 blocks where each block contains 24 trials (8 practice followed by 16 trials). Order of the blocks within each test is counterbalanced; order of the target and the order of the tests are randomised with a short break between every set of 3 IATs, interspersed with physical assessments. Stimuli for the 9 tests are presented in Table[1](#T1){ref-type="table"}, each appearing 4 times in the trials and each appearing twice for the 8 practice trials. Text in italics indicates the non-focal category. The instructions for each test are presented in Table[2](#T2){ref-type="table"}.

![**Setup of the Brief Implicit Association Tests.** Implicit measures of attitude, self-efficacy and intention toward the goal and two behaviours.](1471-2458-12-587-3){#F3}

######

Stimuli of the adapted Brief Implicit Association Tests (italics denote the non-focalvery good, good, fair, poor, very poor to unbearable. The single question self-assessment is based on a previous study demonstrating that a single question self assessment regarding one's health is a reliable indicator of the general health \[[@B130]\].

Quality of life was assessed in using the revised Functional Assessment of Human Immunodeficiency Virus Infection (FAHI) quality of life instrument \[[@B129]\], measuring 5 facets of well-being: physical (13 items), emotional and living with HIV (10 items), functional and global (13 items), social (8 items) and cognitive functioning (6 items).

Validated scales are used to assess conscientiousness \[[@B71]\], need for cognition \[[@B131]\] and social desirability \[[@B132]\]. Activity level during the study is self-reported at each measurement point using the International Physical Activity Questionnaire \[[@B133]\].

The strength of the combination of motivational forces influencing


measures*

The project incorporates objective measures of both exercise and medication adherence. Exercise adherence is assessed via attendance logs during the first phase and self-managed exercise diary during the second phase. Clinically meaningful improvement in fitness and physical indicators (*i.e.* improved fitness level, weight loss, improved circumferential anthropometric measures) also serve as a proxy measure for adherence.

Medical adherence is assessed via self-reports corroborated by non-invasive hair analysis, using 50 mg of cut hair samples. Methods are being developed in house for two HIV drugs, tenofovir and abacavir, as one of the two presents in all treatment combination for this sample. The two drugs are quantified using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) following extraction from the hair samples. Owing to the limitations of the method, hair analysis provides a crude estimationwhich are not identifiable to the research team may be retained.

The project has no foreseeable risk to the participants and their identity is fully protected. The computerised and self-reported psychological tests are coded by the attending physiotherapist and although they present a cognitive challenge, they are completed in segments between the elements of the physical tests. The physical assessment and the 10-week exercise programme are part of the prescribed treatment. None of the physical tests are to exhaustion.

Involvement in an exercise programme could potentially cause temporary pain, discomfort and/or inconvenience but it is part of the standard treatment and the Trust has a generic risk assessment for gym based exercise. In this study, the risks are minimised by prescribing clinically indicated simple exercises that are suitable for each


over-adherent (taking more than expected). Over-adherence has been observed in relation to other medications and linked to the number of pills \[[@B142],[@B143]\] and poor cognition \[[@B143]\], although elsewhere over-adherence was observed at a higher rate among those who were on the once-daily regime \[[@B144]\]. A fluctuating pattern of over- and under-adherence to HAART has been documented \[[@B145]\], suggesting that adherence to HAART is not a stable characteristics thus any observation made based on hair analysis is limited to the study period. Longitudinal study following both medical and exercise adherence, along with potential reasons for over-adherence is warranted. Whilst the medical records provide detailed and accurate information on the drug treatment regime prescribed to the patient, including changes over time, these records may not be the exact reflection ofMutation analysis of the TSC1 and TSC2 genes in Japanese patients with pulmonary lymphangioleiomyomatosis.
Pulmonary lymphangioleiomyomatosis (LAM) is a destructive lung disease characterized by a diffuse hamartomatous proliferation of smooth muscle cells (LAM cells) in the lungs. Pulmonary LAM can occur as an isolated form (sporadic LAM) or in association with tuberous sclerosis complex (TSC) (TSC-LAM), a genetic disorder with autosomal dominant inheritance with various expressivity resulting from mutations of either the TSC1 or TSC2 gene. We examined mutations of both TSC genes in 6 Japanese patients with TSC-LAM and 22 patients with sporadic LAM and identified six unique and novel mutations. TSC2 germline mutations were detected in 2 (33.3%) of 6 patients with TSC-LAM and TSC1 germline mutation in 1 (4.5%) of 22 sporadic LAM patients. In accordance


  logger.fine ("\n");
        }

        // Initialize some structures
        this.t = trans;
        this.input = input;
        this.output = output;
        // xxx Not very efficient when the lattice is actually sparse,
        // especially when the number of states is large and the
        // sequence is long.
        latticeLength = input.size()+1;
        int numStates = t.numStates();
                   if (logger.isLoggable (Level.FINE))
                        logger.fine ("transitionWeight="+transitionWeight+" nodes["+ip+"]["+i+"].alpha="+nodes[ip][i].alpha
                                +" destinationNode.alpha="+destinationNode.alpha);
                    //System.out.println ("destinationNode.alpha <- "+destinationNode.alpha);
                }
            }


// gsc: reducing from 1e-10 to 1e-6
              // gsc: removing the isNaN check, range check will catch the NaN error as well
                            // assert (p >= 0.0 && p <= 1.0+1e-10 && !Double.isNaN(p)) : "xis["+ip+"]["+i+"]["+j+"]="+xi;
              assert (p >= 0.0 && p <= 1.0+1e-6) : "p="+p+", xis["+ip+"]["+i+"]["+j+"]="+xi;
                            if (incrementorhas merit.

25
While Trooper Peech was issuing the citation and running a computer check of Ms. Bradford's records, he chatted with her about the nature of her trip. It is well-established that "[a] law enforcement officer conducting a routine traffic stop may request a driver's license and vehicle registration, run a computer check, and issue a citation." United States v. Elliott, 107 F.3d 810, 813 (10th Cir.1997). Moreover, we have held that during the stop, an officer may ask routine questions about the driver's travel plans. See United States v. Williams, 271 F.3d 1262, 1267 (10th Cir.2001) ("[W]e have repeatedly held (as have other circuits) that questions relating to a driver's travel plans ordinarily fall within the scope of a traffic stop."). Clearly, this was a routine traffic stop


When a "driver voluntarily consents to additional questioning, no further Fourth Amendment seizure or detention occurs." Anderson, 114 F.3d at 1064.

2. Validity of the Search

36
Under the automobile exception to the Fourth Amendment's warrant requirement, "police officers who have probable cause to believe there is contraband inside an automobile that has been stopped on the road may search it without obtaining a warrant." Florida v. Meyers, 466 U.S. 380, 381, 104 S.Ct. 1852, 80 L.Ed.2d 381 (1984) (per curiam); see United States v. Oliver, 363 F.3d 1061, 1068 (10th Cir.2004). "Probable cause to search a vehicle is established if, under the totality of the circumstances, there is a fair probability that the car contains contraband or evidence." United States v. Downs, 151 F.3d 1301, 1303 (10th Cir.1998) (internal quotationF.3d 702, 704 (10th Cir.1997); see also Olano, 507 U.S. at 736, 113 S.Ct. 1770. Although we have noted that "not necessarily. . . all constitutional Booker errors that affect substantial rights also undermine the integrity, fairness, or public reputation of judicial proceedings," Dazey, 403 F.3d at 1179, we believe it is a sound exercise of our discretion to remand this case for resentencing despite Ms. Bradford's failure to assert Blakely/Booker error in the district court. She made "numerous objections" to the presentence report and objected strenuously to the factual basis on which the judge found the additional thirty grams of cocaine. See Sent. Tr. at 3, 5-9. Without the judge-found two-level enhancement based on the additional thirty grams, the top of the guideline range in which she


we shall explain below, we conclude that the district court’s

      2
        Even if we were free to reach the issue, we would reject the government’s
assertion that the district court’s error was not plain at the time the district court
imposed the revocation sentence on Mendiola. The Supreme Court’s decision in
Tapia was issued nearly four months prior to the time the district court imposed
the revocation sentence, and, as we conclude below, Tapia’s holding was clear
and unequivocal.

                                                            10
the defendant or providing the defendant with needed educational or
vocational training, medical care, or other correctional treatment.”)
(emphasis added). The difference in language between 18 U.S.C. §
3583(c), (e) (“term of supervised release”) and 18 U.S.C. § 3582(a)
and 28 U.S.C. § 994(k) (“term of imprisonment”) reinforces the
argument that Congress did not intend the limitations applicable to
an initial sentence of imprisonment to be applicable in redetermining
a sentence of supervised release to include prison time upon the
revocation of the prior term of supervised release.

   The rationale for allowing courts to consider rehabilitation when
incarcerating a defendant upon violation of the conditions of his
supervised release is “especially compelling,” [United States v.]
Giddings, 37 F.3d [1091,


as contemplated by the plain
language of § 3583(e)(3).

   Because [medical and correctional needs] may be considered in
determining the length of the period of supervised release and
because a district court may require a person to serve in prison the
period of supervised release, the statute contemplates that the
medical and correctional needs of the offender will bear on the length

                                   11
      of time an offender serves in prison following revocation of
      supervised release.

Id. at 1215-16 (footnote omitted).

      The panel majoritylimited solely to the question of whether Tapia invalidated
Tsosie.

                                            17
(applying Tapia and concluding that “prison, whether as an initial sentence or on

revocation of supervised release, can be imposed and the duration selected only

for purposes of retribution, deterrence, and incapacitation, not rehabilitation”);

United States v. Molignaro, 649 F.3d 1, 5 (1st Cir. 2011) (Souter, J., sitting by

designation) (“We feel bound [by Tapia] to conclude that rehabilitation concerns

must be treated as out of place at a resentencing to prison [following revocation

of supervised release], just as ordering commitment initially.”).


case committed

plain error when it sentenced Mendiola to a twenty-four month term of

imprisonment, double the length of the upper limit of the recommended guideline

range, for the express purpose of “giv[ing] [Mendiola] enough time to” participate

                                          18
in a 500-hour prison drug and alcohol rehabilitation program. ROA, Vol. 3, at 6.

In Taylor, the Eighth Circuit recently concluded that a nearly-identical revocation

sentence was plainly erroneous in light of Tapia. 679 F.3d at 1007 (“The district

court plainly erred when it sentenced Taylor to twenty-four months while ‘using

that number because that makesUnited States v. Hasan, 526 F.3d 653, 665 (10th Cir.
2008) (internal quotation marks omitted). When revoking Mr. Mendiola’s

supervised release and sentencing him to prison, the district court in this case

varied upward to the statutory maximum of twenty-four months — twice the

guidelines-recommended maximum of twelve months. And it did so for the

express purpose of rendering Mr. Mendiola eligible for a prison drug treatment

program open only to those “that have 24 months [in prison].” ROA, Vol. 3, at 6;

see also id. (“Anybody that goes [into prison for] less than 24 months, they don’t

have” access to the program.). The court cited Mr. Mendiola’s rehabilitative

needs and the prison treatment program no fewer than nine times in the course of

justifying its variance. Plainly, if the district court had known that a statute

prohibited it


has been no waiver in this case, and the fireman's rule bars plaintiffs' recovery.
The third issue on appeal is whether the "deliberate encounter exception" and public policy, requiring landowners to maintain their premises in a reasonably safe condition for their invitees, mandate abrogation of the fireman's rule.
Plaintiffs argue that the "deliberate encounter exception" abrogates the fireman's rule. They assert that pursuant to LaFever v. Kemlite Co., 185 Ill.2d 380, 235 Ill. Dec. 886, 706 N.E.2d 441 (1998), a person who deliberately encounters a known defect is not barred from recovery if the landowner could reasonably foresee that the person would encounter the defect.
Plaintiffs also argue that the fireman's rule must be abandoned because it detracts from the clear and overriding public policy that landowners/occupiers should maintain their premisesin a reasonably safe condition for persons lawfully upon their property.
Defendant responds that LaFever is irrelevant because it does not address the pertinent issue in this case, i.e., whether the fireman's rule bars plaintiff's recovery, and that the supreme court would have addressed this issue if it felt it was relevant.
In LaFever, the supreme court addressed the "deliberate encounter exception" to the open and obvious doctrine. In that case, the driver of an industrial waste truck brought a negligence action against the owner of a fiberglass plant for injuries sustained when he slipped and fell while servicing the plant's waste facility. LaFever, 185 Ill.2d at 385-86, 235 Ill.Dec. 886, 706 N.E.2d at 444-45. Defendant argued that it owed no duty to plaintiff because he encountered an "open and


in assets respectively.

…it has been shown that the inclusion of ESG [Environmental, Social and Governance] factors … is … becoming mainstream… Certainly there is a long way to go but the study[6] clearly shows that pension funds take their fiduciary duty seriously.

This shows that fund managers increasingly consider social responsibility synonymous with long term financial return. Some have claimed that, had SRI been more prevalent, the pensions industry needn’t have taken a hit during the financial crisis[7]. Whilst it seems optimistic to expect SRI to act as insulation for the industry against shocks as widespread as that, certainly SRI can only gain importance in a world where pensions have to look longer and longer term. The ageing population and coming auto-enrolment mean that high and dependable returns willcannabidiol or CBD to replace opioids in the management of chronic and neuropathic pain represents a major opportunity to remediate the opioid epidemic by replacing opioids with cannabinoids like those found in CBD oil.

Responses to an ABC News poll in the USA conducted in 2005 indicated that 19% of adults (38 million) have chronic pain, and 6% (or 12 million) have utilized cannabis in attempts to treat it (ABC News et al 2005).

The discovery of the endocannabinoid system changes everything for medical schools, medical professionals and physicians alike. Although the major discoveries about the endocannabinoid system were made as far back as the early 1990s and much of the research was done in Israel we are still decades away from physicians in America being trained educated and putting


take on horror and it’s one of the better examples of less being more. The film introduces some deeply upsetting aliens that use their evolved sense of hearing to wipe out anything that they identify. A creature with extraordinary hearing that forces you to operate in unnatural ways in order to survive is already a frightening idea, but these things are also bulletproof. These aliens also look like something that William Birkin from Resident Evil 2 would have cooked up in his lab, but they feature a really inspired design that actually makes sense based on the evolution of the aliens. The film features an extremely tense game of cat and mouse that simultaneously feels like something from out of Jurassic Park and Alien. Everything about these monsters,whether it’s their disturbing look, their tremendous abilities, or the complete lack of information that we have on them, makes them a success.

Andre Toulon’s Puppets (Puppet Master: The Littlest Reich)

The Puppet Master series has been kicking around for nearly three decades, but this year’s Puppet Master: The Littlest Reich set out to be a harsh reboot of the quirky series. The film brings back classic murderous toys, Blade, Pinhead, Tunneler, and Torch, but it also adds plenty of new ones into the mix like the uniquely twisted Happy Amphibian, Mr. Pumper, or Money Lender puppets. The film knows that killer puppets are an inherently silly idea, but S. Craig Zahler’s script makes sure to make these tiny terrors as brutal as possible. Lovers get horribly burned and disfigured,


of the haters in your life as sandpaper; they’ll scratch you up time and time again but in the end you’re polished, smooth, and spotless..while they end up useless

We make a living by what we get, but we make a life by what we give.

Posts: 54138 | Registered: Jun 2007 | From: Big Blue Nation

Aubrie♀ 33886Member # 33886

Posted: 11:57 AM, April 28th (Monday), 2014

sign an oath not to pick on me

But...but...but that's the BEST part!!!!!

Welcome to F&G lurkers. Where we discuss pedicures on Moo, put faces to names with picture threads, and Unagie tries to scare the crap out of us with spiders. *cough*

Hobbies? Umm...this is always a tough one for me. Because I don't really feel "hard core passion" for any particular thing. I'm not really goodthe end result.)

Broken crayons still color.

"Courage is being scared to death and saddling up anyway." - J. Wayne

Posts: 6882 | Registered: Nov 2011

norabird♀ 42092Member # 42092

Posted: 12:17 PM, April 28th (Monday), 2014

More members should stop lurking and contribute to the song title game, the alphabet game and word unscrambling game, so that they don't keep dropping down the page! Some of us are reliant on these for our procrastination people, step up!

Sit. Feast on your life.

Posts: 4284 | Registered: Jan 2014 | From: NYC

simplydevastated♀ 25001Member # 25001

Posted: 12:22 PM, April 28th (Monday), 2014

I did the alphabet game...once. Ok, in my defense there were a lot of people posting at once. I really didn't forget the order of the alphabet. Sheesh...

And bad Aubrie! Bad! That verb should be in


has likely attended more G2Gs than any other single member. Or married member!

There's an opportunity to brag about and post pics of your children/grandchildren, follow the antics of Grumpy Cat, and wish fellow members Happy Birthday.

Here is also where you'll find out about any G2G in your area.

Come and join us. We don't bite!

Age: 64..ummmmmmm, no...............65....no...oh, hell born in 1947. You figure it out!

"I could have missed the pain, but I would have had to miss the dance." Garth Brooks

Posts: 7790 | Registered: Jul 2007 | From: Toronto, Canada

simplydevastated♀ 25001Member # 25001

Posted: 12:30 PM, April 28th (Monday), 2014

I made a coffee table and end table. Still need to stain them. But they're functional. And I love them.

(Psst, the pallet garden was a joke. Possible operator error. I justinformation to put me at ease when I brought Cole home. Thank you for this wonderful and practical gift!

http://whereparentstalk.com/testimonials/8421/

My wife and I sat down to watch "the video", with a critical eye. I have nothing more to say than "Excellent!" As a prospective new mommy, my wife found it chock-a-block full of pearls that I of course know as second nature. She suddenly felt the playing field level, thanks to your informative, well done piece.

My wife and I sat down to watch "the video", with a critical eye. I have nothing more to say than "Excellent!" As a prospective new mommy, my wife found it chock-a-block full of pearls that I of course know as second nature. She suddenly felt the playing field level, thanks to your informative,


hopefully it was her delicious stew.

"Good Afternoon Beth," he called to her.

Beth was stirring the stew on the cooker when he entered the room. She joyfully turned around and smiled "My dear Jacob" she walked up to him and lovingly hugged him. "Oh you feel so cold, please quick come inside and make yourself warm." Beth lead him in front of the fireplace, she grabbed the top of his collar and helped him take his coat off.

"I can take my own coat off," Jacob smiled. Beth let him take his coat off but she took it from him and hung it off the back of the front door. He removed his feet from the heavy boots and wrinkled his toes on the comforting thick rug. The feel ofrobe that hung from the back of the door. The once clean dry bathroom rug was now soaked with the droplets of bath water.

"I'm out Beth," Jacob replied to her.

"The kettle is boiling, can I do you a tea?" she asked.

"Please," Jacob stared at himself in the bathroom mirror deciding whether it was worth trimming his untidy beard. Shaving became a difficult task at sea, he soon understood why most fishermen had beards. He filled the sink with warm water and start to first trim his beard before using the razor to remove any hair from his jaw. It took a while but soon his face was beard free. He walked from the bathroom to his bedroom so he could get into warm clean clothes that did not


He could easily reach the peak in a day. The dim sunlight was setting over the horizon and the night chill was returning. Jacob decided to set up camp for the night here and attempt to climb after a few hours' sleep. He was surrounded by a clean blanket of snow for as far as the eye could see. The only disturbance in the blanket were the mountains in front of him although they looked more like steep rocky hills with a frosting of snow.

The moon replaced the sun as it slept. The moonlight reflected off the snow and provided Jacob with a dazzling sight. Each fallen snow flake sparkled in the moonlight. To have such a beautiful view around him helped him feel at ease. Jacob pitchedrucksack packed it was time for Jacob to make his climb. He walked through the last of the blanket of snow until he reached the rocked terrain of the mountain. The first few hundred meters were a steady incline along a snow-laden gravel trail littered with boulders. Each footstep crunched into the deep snow. With every hundred meters Jacob walked the snow became shallower. To his surprise he saw a single fern tree standing next to the trail. It was an odd sight given there was no other sign of life for miles around. Jacob decided to take a breather next to the fern. Icicles dangled from the branches with droplets of water falling into the bed of snow beneath.

Jacob had been walking for an hour now and


the city.

CHAPTER FOUR

Noriea was surrounded by dying farm land. Despite the harshness of the land a small amount of crops managed to grow. Jacob walked through the field, avoiding the trivial crops. At the foot of the field a stone wall surrounded the city. There were several wooden gates allowing entrance. The first Jacob had approached was closed. He did not knock or make a sound instead he decided to try a few more in case one was open, that way he would keep his presence to a minimum. The second and third gate were both closed, but the fourth was still open. Jacob noticed the footprints of the two men who had ran from the city. Not far from the gates a whaling woman was on herat Jacob. "You are not from around here are you?"

"No I'm not, I'm from a small fishing village north of here."

"Why ever have you travelled down here especially at this hour? Did the Soldiers come to your village, we saw a couple of scout ships return from the north a week ago?"

"Sort of, but I'd rather not talk about it, I just need some rest." Jacob pushed the coins closer to her hand.

"Sorry dear I don't mean to keep you, your room is the second on the left upstairs. Perhaps I can prepare some breakfast for you in the morning?" She handed him the key.

"Thank you that would be great." He took the key and made his way to the room.

To Jacob's surprise his room was very much


the summer months we could grow enough food to last the winter."

"Well done you," he laughed sarcastically.

The girl returned with their drinks. In old mugs the steam evaporated from the warm, weak coffee. She placed two paper coasters on the table and the drinks on top. She smiled at both of them and walked over to another table.

"Do you not need to pay?" Jacob asked.

"When we leave I will, this place is based on trust."

"If it is based on trust then why have you not yet told me your name?"

"You have not asked," he laughed. "My name is Erik, I am the son of the North Commander of The People's Army, and we are the resistance."

"The resistance? You don't exactly seem to have much of a presence here.brick wall. Inside the factory was comprised of two steal built warehouses. Two chimneys rose from behind with thick black smoke that escaped into the sky. The conveyer belt had halted since the siren had begun. The factory was deserted, the machines stopped and for a moment there was silence.

"Beneath the furnace we will find our exit. When get there we blow the entrance, we can't risk the chances of being followed," Erik led the way.

The wind blew dust through the courtyard. A bronze statue of the previous Chancellor stood motionless in the centre. Jacob stood before it.

"You know this is the first time I've laid eyes on my father."

"As much as I care for sentimental moments, we really don't have time." Erik pulled Jacob away from the


above them, the heat was almost unbearable. Once the fireball had passed the whole cave began to violently shake.

"Run," Erik picked up Jacob.

They both ran further into the cave. Rocks fell from the ceiling, dust rushed past. The furnace caved in behind them. They ran down a small tunnel, the dull jagged rocks reflected no light from their headlights. After a few minutes Erik slowed down the pace.

"We should be okay for now, here take this," Erik passed Jacob a bottle of water from his bag.

Jacob took a long refreshing gulp from the bottle. "Thanks. Are you sure they can't follow us?"

"Did you not hear the explosion behind us, we will soon be far away from here. Don't drink it all," Erik took the bottle from Jacob. "Wethey were he did not know but he had hoped they would still be edible. He placed them in his pocket and continued his search.

Jacob walked behind the counter and found a doorway to another room. He strolled through to the rear of the building. There were two bookcases stacked with several folders. A desk sat in front of another boarded window. Cobwebs dangled from the ceiling and wrapped themselves around an old computer on the desk. On the other side of the desk a large leather chair faced the window. Jacob placed the flare on the floor and approached the chair. He could make out the shape of someone's head just above the back of the chair.

"Hello?" he uttered. There was no replied so he spoke again.


and squinted in the light. He heard a bird squawk outside, it sounded similar to the one he had seen on the factory floor. The squawk was interrupted by the approaching sound of an engine. The dust on the counter shook with the vibrations of the wheels. This was a large vehicle approaching. It did not sound like previous vehicles he had seen soldiers drive or even fly, but like that of an old petrol engine. Jacob had decided to stay put, he had to make sure it was no one hostile.

The beams of sunlight were interrupted by the vehicle pulling up outside. The engine stopped. Jacob began to breathe more quickly unsure of who they were. The doors of the vehicle opened. He could here footsteps andof us that equals two each doesn't it?" Jacob used his hands to place two pieces of fish in front of each wolf. He then ate the remaining sardines. Jacob could not tell how long the can had been on the floor for but they tasted fresh. The wolves seemed to agree too and they quickly devoured the fish. The first wolf barked again.

"Sorry boys I'm all out," Jacob pulled his pockets inside out.

The second wolf barked and they both rose to their feet. They looked at Jacob one last time and walked outside. Jacob was unsure exactly what had just happened, why would two hungry wolves save him? Not that he minded, after all he could do with two guardian wolves looking over him. Jacob grabbed his


the drama of the previous day he had forgotten his need for the toilet. Ideally he did not want to relieve himself against the wall of the petrol station.

Jacob walked to the side and found a little brick outhouse. This was in worse shape than the main building. Its decayed wooden door hung from a single hinge. He opened the door and it fell off its hinges and onto to the floor. Inside the outhouse a foul stench escaped. Jacob coughed and tried to hold down vomit. Even the corpse didn't smell as bad as the outhouse. He entered none the less, there was a toilet, sink and a cracked, filthy mirror. First Jacob stood in front of the toilet, the water inside discoloured from the stains offrom his coat and trousers.

In the distance Jacob heard the tires on the van screech to a halt. They had spotted him. Jacob ran back to the doorway of the church and crouched. He reached into his bag and pulled out the metal box, inside he grabbed the gun. It was an old revolver with a bullet in each chamber, with six bullets he would have to make each bullet count if it came to it.

The van reversed and stopped at the entrance to the churchyard. It was the same father and son from the previous day.

"Did you see which way he went?" the father asked as he jumped out the van.

"He's somewhere over by the church," the son replied.

"Grab the guns from the back, remember don't kill


the door. After the fifth shot the wood began to penetrate. He then used the handle of his gun to make a bigger hole in the door.

Jacob looked from the sink and fired at the door. The bullet missed and hit the bookshelf. He was now down to only four bullets.

"Don't try and be a hero," the father shouted through. He kicked the weakened door a few more times and it created an opening big enough to climb through. "You take that side I'll take this." They both crawled up each side of the church.

Jacob fired another shot at the son but missed again. The son fired back and cracked marble from the sink. Water splashed over the floor. Jacob saw the father get closer so fired ato the right to scan the walls. The white wall tiles had been stained with age and mould grew from each of their edges. Rotten posters were glued to the walls, they displayed adverts for various concerts and films, none of which really meant anything to Jacob.

Since Jacob had arrived at the city he had felt he had travelled to another place in time. Whilst the city was in ruins it had a very modern feel to it, at least compared to what he was used to in his old village. He knew that if he was impressed by modern nature of this city albeit ruined, then perhaps nothing could prepare him for when he finally saw the ark.

The stairway came to an end and Jacob now found


Jacob replied. There was no reply to Jacob, he took the silence for a yes. "Very well," he murmured. With his arms still covering his eyes he steadily knelt on his knees. "There you go!" he shouted.

A shadow walked from out the light. The man stood in front of Jacob and grabbed his arm. Jacob wanted to resist but thought better of it. He rolled up Jacob's sleeve and turned his arm over. He moved his finger along the backside of his arm.

"That's just a birthmark," Jacob pointed out the faded red pattern on the inner of his wrist.

"We've found him," the man shouted and loosened Jacob's arm.

"Lights!" the voice shouted again.

The lights switched off and Jacob lowered his other arm, he could see again. Jacob stood upwere not worthy of it." Caster paused for a moment.

"Do you want some time?" Jacob didn't know how else to continue the conversation.

"I once read, the fear of death follows from the fear of life. A man who lives fully is prepared to die at any time. I have always prepared myself and anyone who follows me for our eventual oblivion. Erik will be rewarded in the afterlife."

"It looks like I'm done here," Parmjit had finished stitching up Jacob's arm. "I hope that didn't hurt too much."

"Don't worry I think I handled the pain well enough," Jacob smiled.

"If you don't mind Commander I will excuse myself."

"Thank you for your help dear," Caster excused Parmjit.

"So where have you brought me?" Jacob asked Caster.

"At the moment we are sat below


the flavours of food being cooked in the kitchen next door. He walked up to an empty seat at the end of the table and sat down. Three strong muscular men were sat around him, they all stopped eating and looked Jacob up and down.

"So you're our little celebrity," the closest snarled with a mouthful of food.

"That is correct Tomkin, Jacob is the very reason we are all heading back to Arcadia," Caster declared to the room. There was a small cheer. "Today we shall prepare to move out and tomorrow our landers will take us." This again was followed by another cheer. "Gentlemen please welcome Jacob whilst I see to some other business," Caster left Jacob in the hands of the three around him.

"Well it's about bloodywet," Gunnar jovially punched Jacob in his good arm.

"Behave Gunnar, he was simply doing what all you depraved men would do, well except you Gunnar you're far more depraved then the rest of them." Gunnar's smiled quickly turned to a frown.

"Apologies about that," Jacob spoke between mouthfuls.

"Don't worry yourself," Astrid accepted his apology.

"Are you not eating?" Ivar pipped up.

"I ate earlier. So has the Commander told you all the good news?"

"Yes he has, we pack up and get the hell out of here," Ivar replied.

"Not quite, first he wants us four to do another perimeter search and just make sure the path is clear."

All three men groaned together. "Always the bringer of good news aren't you?" Tomkin stood up from the table. "I guess we had better suit


discoloured from the dried blood and dust, it trickled away through the drain in the middle of the room. Jacob grabbed one of the towels and dried his body. Sure to her word Astrid left a clean set of clothes on the bench. It felt refreshing not to have to wear the same dirty, worn clothes. He put on the clean underwear, combat trousers and t-shirt. He still had the same pair of boots and jacket which he did not mind. Dressed Jacob left the shower room and headed upstairs to meet the others.

chapter ten

A mouse scampered across a clean marble floor next to a varnished skirting board. It could sense the odour of cheese ahead. It stayed close to the wall not to give way its presence.walked back to the group.

"In case you hadn't figured it out yet, put the mask on if a storm approaches," Astrid threw the mask to Jacob. "Have you used one of these before," she then handed him the rifle.

"I've had a go once or twice," Jacob strapped the mask to the rifle and placed it over his shoulder.

"We had better go," Tomkin led the way and opened the heavy timber doors.

The doors opened and the bright morning sunlight lit up the doorway. Jacob followed and stood on the threshold to figure out where he was. He could see the park he had walked through not too far down the street. The church stood atop a flight of stairs that lead out onto the street. The structure of the


cabinet slid across the floor and toward the hole above Jacob's head. He saw the top of the cabinet appear. At first Jacob did not react there was no sign of it moving anymore.

"Jacob, what was that?" Astrid called out.

"Just the wind, nothing to worry about," Jacob ignored the cabinet and carried on. Just as he did the floor above weakened and cracked. The cabinet slid further and fell over the edge. As it fell it hit the other floors bringing down more debris with it. Jacob heard the falling cabinet and jumped from where he was standing. He looked around and luckily the cabinet and debris had landed away from him.

Astrid ran over to Jacob. "I thought you said it was just the wind."

"It was, how wasI don't think any of us have. Not since you spoke to him," Caster replied.

"He must have gone back to them, the traitor's turned his back on us," Gunnar growled.

"Only time will tell," Caster said.

An out of breath Tomkin quickly returned from below with a metal case. He rested it on a pew and took two deep breaths. "Got it."

"Do you know how to use it?" Caster asked.

"I flick the switch," Tomkin laughed.

"Yeah not much to it other than that. Just remember you need to be at least a metre near the Mech for it to work," Caster rested his hand on Tomkin's shoulder. "Good luck out there."

"Sorry can I just interrupt... What's an EMP?" Jacob asked.

"Electromagnetic pulse. We switch this on and it will send out a


Unable to find it in her pockets she scanned the room. "There," she saw it near a chair on the far side of the room.

"Leave it, the pipe is going to rupture any minute," Jacob grabbed her arm.

Parmjit pulled away and ran over to the necklace. She crouched down and picked it up. Another violent explosion sent her to the floor and she fell against the far-side wall. The pipe above her head cracked open and sent out a slew of gas. She looked over to Jacob with fear.

"Parmjit, slowly crawl over to me," Jacob held his arm out.

She nervously crawled across the floor but one of the metal bangles around her wrist scratched the floor. It created the tiniest of sparks but it was enough to igniteThe sunlight glistened off the ground far below and for a moment it reminded Jacob of the sunrise near the shore of his village that had left him speechless two weeks ago. Except it was not the ocean the sun was glistening off. Wetlands stretched for miles across the horizon.

There were no rivers or lakes but simply one huge body of water. It was covered by low-growing shrubs, the water was not as clear as the ocean but instead a dark, murky green. There was a low light mist that hovered across the water. Oddly enough Jacob saw a lone brown bear walking through the water which rose up to its lower body so it was not very deep. However, the bear's body was lined with a layer


through the sky at an incredible speed. On approach to the cave she opened up her arms and legs and the chutes appeared. Her body flung back with the force of the air brake. She slowed down and glided downwards elegantly. Her body coasted over to Jacob and she closed in her arms to bring herself to a sudden halt running as she hit the floor. Jacob turned around in amazement.

"Wow, that was pretty impressive," Jacob ran over to Astrid.

"Convinced yet?" she smirked at Atreus.

"Whilst I'll admit that was pretty impressive I would argue that you know perfectly well what your destination is, what speed and angle to enter the cave. However, when facing the Ark from forty thousand feet how can you possible know how to glideenough to see from the street. At the front of the apartments were artificial gardens. Some of the residents had either paved over the front or kept the garden. The artificial grass was easy to manage especially as it didn't grow. There were all sorts of different potted flower beds with an array of colours, trees and hedges. Unusual street lamps led further into the Region, the bright spots of light were suspended in the air on their own. They looked like lines of fireflies. The streets were made from a toughened dark glass like material and there was a dark blue illuminated pulse that flickered down the street.

On the streets were cars nothing like Jacob had seen before. The cars hovered a couple of inches from the


hell'," and other colourful words were sprayed over it. Jacob assumed the statue was one of the older chancellors. All of the restaurants in the square had closed up for the night, however the bars were still open. A nightclub stood opposite, loud techno music echoed across the square. Revellers pilled out onto the square from each bar. Most were dressed in brightly coloured florescent clothes. The women either wore small dresses or tight trousers, the men in tight tank tops or baggy hoodies. They all wore heavy workmen boots regardless of their attire.

There was a unique large neon sign above the club that lit up the square reading 'Genesis'. Atreus led the group across the crowded square and toward the club. Jacob pushed through the crowd, hethe beginning God created the heavens and the earth," the DJ addressed his audience. "Now the earth was formless and empty, darkness was over the surface of the deep, and the Spirit of God was hovering over the waters. And God said, let there be light, and there was light."

When he finished his speech a slow beat of music increased and the spot light dimed. Strobes ignited in the ceiling and the beats in the music intensified. The crowd cheered with their arms raised in the air. Those sat at the tables had moved onto the dancefloor and the entire club was embraced in the beat of the DJ's harmony.

The waitress stood at the bar and waved over to Atreus.

"Follow me," Atreus stood up and they walked over


the Guardians.

"What's with their ridiculous faceplates?" Astrid smirked.

"Except for the Lord Commander the Guardians are the faceless protectors of the Ark, they are the elite few trained to protect the Chancellor at all costs," Atreus explained.

The two rows of Guardians stopped, they turned and faced each other. They left enough space for Kaelen to appear at the rear. He stood powerfully in his chrome plated armour. Kaelen did not carry a projectile weapon, instead a large samurai sword was drawn at his side. Rather than a faceless helmet Kaelen wore a chrome spiked headpiece with a golden trim. He looked very much the leader as he paced down the line of men.

"Wow all they need now is to roll out the red carpet," Astrid continued to joke.

"Astrid Ihot and humid inside, there was very little visibility amongst the dust. Caster used the map on his wrist to give them some visibility.

"Where's Pelops?" Caster asked Atreus.

Atreus lay against the ladder and rested his head. "He's helping us escape."

"By getting caught?" Jacob asked.

"He knows what's he doing, now come on let's get moving," Atreus pushed past Jacob. "The weapons, where are they?"

"Here," Caster threw Atreus a rifle. "We found them behind the barrels, three rifles and two pistols."

Gunnar threw two barrels across the floor, behind them were wooden panels. Gunnar used the butt of the gun against the panels. After three attempts the panels cracked. He dropped the gun and used his elbow to remove the remaining wood. He stood back in disgust.

"That smells awful," Gunnar held


his nose.

"It is the sewer," Astrid laughed. She walked up to him and nudged him in the back. "Go on then."

"I'm not going first," Gunnar refused.

"Gunnar just get your ass in there now!" Caster ordered.

"Christ sake," Gunnar murmured to himself. He ducked and climbed into the dank sewer. He crouched as the ceiling was too low to stand up fully. The entire sewer was built from old cobblestone, moss grew between the cracks in the stones. Gunnar's feet were submerged in three inches of dirty slimy water. To his horror he saw a lump of faeces floating near his foot.

Above Atreus could hear the heavy footsteps of the Guardians taking his father away as they all entered the sewer. Caster made his way to the front and ledand hit the wall with a thud. He slid down to his knees to keep out of sight. Jacob waved to Atreus, it was his turn.

Atreus closed his eyes momentarily and took a deep breath. At this point the Mech was moving back towards Atreus continuing with its barrage on the apartments. Atreus stood up and ran to Jacob.

"What now?" Jacob asked Atreus as he too slumped to his knees.

"Well we need an electromagnetic pulse to put that bitch to its knees."

"And exactly how do you suppose we do that? In case you didn't noticed Caster never packed us a bomb," Jacob laughed.

The Mech had stopped firing, but was now searching each apartment it had opened up for any sign of them.

"With the right parts I can make


and coughed up blood.

"Come one Freyja," Atreus held her arm and escorted her out.

Kaelen rolled over and saw the four of them leaving. "Hey!" he screamed.

Atreus stopped and turned to him. "Looks like you weren't the smarter one after all."

"Atreus, you can't leave me here!" Kaelen tried to get to his feet but fell into the bed against the wall.

"Goodbye Kaelen," Atreus smiled as he closed the door.

"Atreus!" Kaelen shouted. He was left alone in the dark.

CHAPTER TWENTY

Gunnar was sat in the middle of the doorway of the stairwell to the control room. A blanket of empty bullet shells surrounded him. He had used round after round to keep the guards below at bay. He had not managed to disarm any of them but had fired enough bulletsand started to climb. Once she was just above Caster he too started his ascent. Max did not hang about, the moment he saw the two of them he pulled away and began their escape. Gunnar pulled himself into the helicopter and immediately grabbed a rifle. He fired at the soldiers below to give Caster and Nancy enough cover. Astrid climbed on board and sat behind Max.

"We need to get the others!" she shouted.

In Region Three Jacob and Atreus led Rebekah and Freyja to the beam of light in the Arch. Atreus sat on the floor for a moment, his fight with Kaelen had taken all of his energy. His leg was bleeding and he was short of breath. Even here they could all hear the echo of


room was spinning, his vision was blurred and he lost sense of where he was for a moment. Jacob rubbed his sore neck, he coughed and sat up. He looked over at Esau who crawled along the floor.

"Hey," Jacob tried to shout but his throat was too sore.

Esau looked back at Jacob and crawled away. He climbed up and jumped over the wall into the street to try and escape yet again. Jacob rolled onto his feet and staggered through the warehouse and climbed outside. They both stumbled through the street. Esau headed past the ruined station and towards the wall. Next to an unmanned security post were a set of ladders that led to the top of the wall. Small steel bars rose vertically along the wall.

App Engine 1.6 out with Python 2.7, Map/Reduce in the SDK - jconley
http://googleappengine.blogspot.com/2011/11/app-engine-160-out-of-preview-release.html

======
tosh
From my POV google app engine is still the only PaaS offering that can scale
the data-tier. Scaling the application instances is a lot easier and most
other PaaS providers struggle with that too.

I think if you look at the big picture GAE is as good as it gets at the moment
and there is quite a gap to the second place when it comes to automatic
scaling.

Am I missing something? Disclaimer: we are very happy and excited GAE
customers with <https://blossom.io>

~~~
bad_user
I'm a GAE user for a personal app -- basically I use it for serving comments
on my personal blog, similar to whatever Disqus is doing but I prefer the
control. I also built on it 2 other personal apps that I


Bad HabitsAre you still smoking cigarettes? What about consuming alcohol? If you are, do what you have to do to quit. Either of these vices can give you short-term pleasure, but they do serious damage to your overall mental health. Excessive drinking can actually boost stress and may lead to depression, and smoking can increase tension.You can achieve a much better frame of mind, and live a lot longer, by changing your ways. If that’s not motivation enough to quit, you can also save quite a bit of money by ridding yourself of these vices.6. Ask for Help When NeededThere’s nothing wrong with asking for help if you’re worried about your mental health, and it doesn’t necessarily have to involve a professional service — although that might bea good idea if you believe your condition is serious. Reach out to friends or family members and simply tell them you haven’t been feeling well. Open up an honest line of communication and you’re sure to find ways to alleviate the problems.7. Do More of What Makes You HappyIf you like playing golf, do more of it. Enjoy crossword puzzles? Schedule more time for them. Whatever it is in life that makes you happy – as long as it doesn’t have consequences detrimental to your health — commit to doing it more often.It’s way too easy to get caught up in the hustle of professional life, or get overwhelmed by stress, but stress cannot cure any problems. Identify the activities that bring you happiness and find more


            *      *       *

      The requested fees include work performed and costs incurred through
August 20, 2018. Petitioner’s motion for fees and costs was not accompanied by
any argument in support of the legal basis for his request.

       Respondent filed his response to petitioner’s motion. Respondent did not
provide any objection to petitioner’s request. Resp’t’s Resp., filed Nov. 9, 2018, at
2. Instead, respondent stated that he “defers to the Special Master to determine
whether or not petitioner has met the legal standard for an interim costs award.”
Respondent did not address whether the statutory requirements for an award of
attorney’s feesthe requested hours as unreasonable.

                                            4
      Mr. Bolton’s billing entries are sufficiently detailed to conclude that the time
he spent working on Mr. Landis’s case was reasonable. Mr. Landis is awarded the
amount requested, $50,750.00.2

      C.     Costs
       Mr. Landis requests $17,865 in attorney’s costs. In his General Order #9
statement, Mr. Landis states that he did not incur any costs. For his attorney,
routine items, such as costs associated


This amount represents reimbursement attorneys’ fees and other litigation
costs available under 42 U.S.C. § 300aa-15(e). In the absence of a motion for
review filed pursuant to RCFC Appendix B, the clerk of the court is directed to
enter judgment herewith.
                                                      s/Christian J. Moran
                                  Q:

What implicit conversions are supported when using < and > operators?

I have got a struct:
public struct Decibel
{
    public readonly double Value;

    public Decibel (double value)
    {
        Value = value;
    }

    public static implicit operator Decibel (double decibels)
    {
        return new Decibel (decibels);
    }

    public static implicit operator double (Decibel decibels)
    {
        return decibels.Value;
    }
}

And now I can do:
bool x = new Decibel (0) < new Decibel (1);

It seems the compiler is smart enough to convert Decibel to


Introduction {#s1}
============

Pentraxin 3 (PTX3), a member of a superfamily of acute-phase reactants highly conserved during evolution and characterized by a cyclic multimeric structure and a "pentraxin domain" in their carboxy-terminus, figures crucially in innate immunity [@pone.0094073-Garlanda1], [@pone.0094073-Bottazzi1]. In response to inflammatory signals, the liver produces the classic short pentraxin C-reactive protein (CRP) [@pone.0094073-Pepys1], which strongly associates with cardiometabolic disorders such as obesity, metabolic syndrome, diabetes mellitus, and atherosclerosis [@pone.0094073-Ridker1]. In contrast, a variety of immune and resident cells involved in cardiometabolic disorders --- including macrophages, dendritic cells, fibroblasts, smooth muscle cells, endothelial cells, and adipocytes --- secrete the long pentraxin PTX3 [@pone.0094073-Garlanda1]. While some previous clinical and preclinical studies report pro-inflammatory properties of PTX3, others show its anti-inflammatory actions [@pone.0094073-Inoue1]--[@pone.0094073-Suzuki2]. Thus, the role of PTX3 in the pathogenesisregions on chromosomes 3, 6 and 14 (Figure [1a](#F1){ref-type="fig"}). Fine-mapping of those three regions confirmed and defined the regions to 3q25, 6q14 and 14q32. By reanalyzing a previously published linkage analysis in 14 large high-risk breast cancer families \[[@R26]\] but coding all cancers to define affected status, three additional loci showed HLOD scores above one, on chromosomes 3, 5 and 6 (Figure [1b](#F1){ref-type="fig"}). Both regions on chromosome 3q and 6q overlapped with those obtained in the previous analysis in moderate-risk families.

![Linkage analysis revealed genomic regions with HLOD score above one in: a) families with moderate risk of breast cancer and b) High risk breast cancer families with other types of cancer](oncotarget-08-102769-g001){#F1}

Fine-mapping of the 6q region was conducted using a total of 43 families. Only two unrelated families, 6006


and 6043, shared a unique 2.8 Mb haplotype between the markers D6S1625 and rs2050660 on chromosome 6q14.1 (Figure [2](#F2){ref-type="fig"}). Max LOD scores of 1.48 for family 6006 and 0.78 for family 6043 were observed, which were among the highest for the families included in the linkage analysis. To assess whether the two families are related, we searched the linkage data for other shared and possibly linked regions and identified two more, one on chromosome 7 and one on chromosome 10. Fine-mapping of both regions (data not shown) demonstrated that the only linked region shared was on chromosome 6q. Thus, the families were considered not closely related. The finding of a shared haplotype in affected cases in both families together with the overall weak support for a region onmight explain the difficulties to identify the two original families' haplotypes since they are not over-represented among familial samples (Table [2](#T2){ref-type="table"}). It was not until it was possible to study also sporadic breast cancer samples within BCAC that evidence was found for the families' haplotypes to act as risk alleles in breast cancer. It was most clear in SASBAC with postmenopausal cases.

The target for the risk association is between our original borders D6S1625 - rs2050660 and in this region there are several genes such as *HTR1B, MEI4, IRAK1BP1, PHIP, HMGN3, LCA5* and *SH3BGRL2* as well as several different RNAs. The *HTR1B* gene has been suggested to be involved in breast cancer progression \[[@R27]\] and the *HMGN3* gene has been published to be upregulated in breast cancer cell lines


Dr. Whiting alleges that the denial arose from ill will between her and her department chair, Dr. Thames, the daughter of the USM president. Accordingly, Dr. Whiting sued on several constitutional claims under 42 U.S.C. § 1983 and on state law-based contracts issues. The district court dismissed the constitutional claims on a motion for summary judgment and remanded the state-law claims to state court. Dr. Whiting now appeals.

2
Because Dr. Whiting has failed to establish genuine questions of material facts for key elements of her due process, equal protection, and First Amendment retaliation claims under 42 U.S.C. § 1983, we affirm the district court's motion for summary judgment.1 As the only issues remaining are therefore questions of state contract law, we find no abuse of discretion in the districtDr. Thames and another faculty member, Dr. Reeves, "began a quest to scuttle [her] career," by intimating that Dr. Whiting had committed academic fraud. Dr. Whiting further alleges that Dr. Thames sought to isolate Dr. Whiting through departmental cliques and by placing her in a separate building from the rest of the faculty. She also alleges that Dr. Thames was displeased by Dr. Whiting's remarks about student rights that reflected poorly on Dr. Thames' administration of the department.

7
USM's review of Dr. Whiting's application began with a committee of faculty from her department. At their meeting, questions arose over certain articles listed in the publication section of her dossier. The committee chair and Dr. Thames met with Dr. Whiting and requested a written response to these questions. Dr. Whiting


request deferral to her seventh year.

10
Dr. Whiting chose to continue with the promotion and tenure process. Accordingly, her dossier came before the University Advisory Council ("UAC"). The UAC met twice to review her materials. On the advice of her attorney, Dr. Whiting declined invitations to attend these meetings, and presented UAC members with a letter alleging failures of due process and violation of her due process rights under the Fourteenth Amendment. Ultimately, the UAC voted to award tenure (five voted in favor, three against, and one recusal), but did not reach a conclusion as to promotion (four in favor, four against, and one recusal). Those votes, in addition to another supplementary letter from Dr. Whiting, were then submitted to the Provost, who concurred with the UAC's recommendation asif, in her annual evaluations and third year review, she meets or exceeds the criteria used for evaluation, then "she is to be tenured." Appellant's Brief at 21. This flat guarantee, she asserts, is sufficient to create a property interest. Language in the Faculty Handbook, however, consistently reiterates that promotion and tenure are not guaranteed, even by positive performance reviews: the Handbook states, for example, "[p]romotion in academic rank is not guaranteed by contracted employment or earned solely by the duration of employment" and "[t]he privilege of tenure is not guaranteed by tenure-track appointment, by prior promotion in academic rank, or by duration of employment." Further, as the district court noted: "the same faculty handbook reiterates that, notwithstanding the procedures, tenure is awarded at the discretion of the


basis for the difference in treatment."3 Id. at 564, 120 S.Ct. 1073.

46
In support of her claim, Dr. Whiting reviewed the CVs of other professors who had traversed the process and received tenure at USM. She argues that her dossier documents a far greater array of accomplishments than possessed by others who had received tenure. All but two of these professors, some of whom belonged to other departments of the university, had gone through the tenure process at different times, were evaluated by different committees, and sought different positions than Dr. Whiting. Of the remaining two, one came from a different department, and the other worked in a different area of teaching and research. Dr. Whiting does not contest that both she and other tenure applicants are evaluated underSignificant advances in therapy for heart failure (HF) with impaired systolic function have improved quality of life, and increased survival. However up to 50% of patients who have clinical evidence of HF are found to have a relatively (or near) normal left ventricular ejection fraction (HF with normal left ventricular (LV) ejection fraction syndrome (HFnEF), also referred to as HF with preserved left ventricular ejection fraction syndrome (HFpEF). Patients with HFnEF represent a rapidly increasing proportion of patients hospitalised and suffering mortality from heart failure.
Despite a normal EF, HFnEF patients manifest subtle systolic dysfunction but the principal abnormality in most is a disorder of active relaxation and/or passive filling of the LV. However resting measures of active relaxation and filling relate poorly to symptoms and exercise capacity therefore


to gain. So the net benefit from bitcoin is zero, it merely shifts money from one person’s pocket to another. Just like property development, the people who get in first make a lot of money, but the last person left with the house finds no one to sell to and is left holding the bag (unless of course the first people are foolish enough to buy it back).

All bubbles thrive so long as no one tries to cash out. During the boom, we were all delighted at how much the value of our houses had risen. However, like bitcoin, this was all paper money and could disappear as fast as it arrived. What people didn’t realise was that the price was high because people weren’t selling; because theMagpies also said defender Ben Reid was unlikely to play in round one with the club taking a conservative approach to his recovery from a hamstring injury.

He said Paul Seedsman and Darcy Moore played in Collingwood's VFL trial match on Friday and would play again against the Tigers on Thursday night in a VFL practice match.


through distributors, catalog houses and original equipment ...

SKIMOIL INC. is a specialty design/custom manufacturer-builder, and distributor of marine and industrial pollution control equipment and systems. We specialize in all types of industrial oil skimmers and oil water separators. With just a few exceptions almost everything we do touches on oil somehow.

AIRSYS is a leading manufacturer in hydrocyclone separation solutions. We are recognized in Korea & China for its knowledge and expertise in the use of hydrocyclones for Solid/Liquid separation, Liquid/Liquid separation etc. AIRSYS will continuously improve the technology with environment, power generation, food, chemical, electronic, steel, mineral, shipbuilding and all ...the crisis is the perfect time to promote low-cost brands.

Furthermore the crisis will not last forever, and moderate optimists are already talking about some of the notes of the weak recovery. The first improvement in economic conditions will feel only those companies that actively promote their products and services. In conclusion I wish to summarize: 1. From advertising will no longer be, but need thoroughly analyze its effectiveness. 2. Necessary to significantly reduce prices. 3. The range of goods and services must pay special attention to low-cost types, as well as the possibility of offering customers a decent alternative to expensive goods and services.

12 you will find pieces of cream of rice, House doctor, Sebra and apparatus, Nordal is a small online shop to browse and fall in


In our showroom in uberlingen on Lake Constance, port str. 6, our customers can a personal impression Danish lifestyles get and is kidnapped in this colorful world. The majority of our customers combine their visit with a trip to the scenic Lake Constance. Living like lunoa.de: the new collection of rice and House doctor is beautiful along with the detailed lamps by Taj Wood simply fabulous. Stylish decorating, lamps, quilts and baskets provide much inspiration for your home. Especially to the heart we want also the seat cushions and textiles. For the right summer feeling look but our joys of summer with the funny acrylic painting glass.

Kitchen love lunoa.de: table and kitchen happier to make with the colorful melamine series of rice which is ideal for daily use,exhibition.

The company Bozita/robur offers on Saturday, November 13th, receive advice on the optimal nutrition for your dog. Employees can problems with your dog or your cat advice stand to the side, in the selection of the correct feed or the appropriate dietary supplement, for example the company grey, help you. On two days of the fair many well-known will offer various actions manufacturers of pet supplies, such as Royal Canin, Animonda, and happy dog, where you can save by the way too much money. The employees of Mair can you through your experience with aquariums, ponds and all kinds of domestic animals in many areas, helping to assist and advise you competently. Description of the company since 1997, is the company Aquarium shop Mair in Schrobenhausen, Germany established


have contested for control of a ruined economy and savaged society.

Yet this Washington lifer has the nerve to attack Trump’s small but welcome step toward disengagement!

As we said, Imperial Washington inhabits a looney bin. And as we indicated in Part 1, the picture below is indeed the "smoking gun".

It’s the handiwork of a pair of American F-15s which bombed a large ammo storage dump US forces had hastily vacated near Kobani on the Syria/Turkey border.

The purpose, as we explained in Part 1 above, was to insure that it did not end up in hostile hands. That is to say, the Turkey-backed Syrian National Army, nee the Free Syrian Army (FSA) – otherwise actually the John McCain Memorial Brigade, which was brought, trained, paid-for and stood-up by the CIA.

Moreover,points as the neocons, liberal war hawks and warmongering Republicans.

That could not have been more evident during the last week than in their blatant, incessant misuse of the words “ethnic cleansing” and “genocide” in describing Turkey’s threatened invasion.

But the Syrian Observatory reported as recently as Thursday that contrary to the hysteria, the violence to date has been overwhelmingly against Kurdish SDF units. By its reckoning, 274 SDF soldiers have been killed – combatants who did not hesitate to return the fire in-kind toward the advancing Syrian National Army invaders of their towns and communities.

Unfortunately, a reported 72 civilians were also killed in the first eight days of the Turkey’s offensive, which is 72 too many, but in no way shape or form does it constitute an ethnic cleaning.

More


importantly, all of these crocodile tears completely ignore the history of why the thin red corridor depicted in the enlarged map below has become such a tinderbox after Washington’s bull-in-the-china-shop intrusions into the age-old sectarian fissures and political conflicts of the region.

To begin, the Kurds did not bleed and die in behalf of American security and liberty. They fought ISIS and gladly received American money and weapons in defense of their own communities – after Washington unleashed the US armed ISIS marauders into their regions.

The 10,000 who were killed in the 2015-2017 battles with ISIS, died protecting their own homes and villages from the barbarians who arrived in US military vehicles toting US guns and artillery left behind in Iraq or sent to anti-Assad forces in Syria, whofuriously denouncing.

But not back then, as the Queen of Warmongers (hat tip to Tulsi) coldly averred:

“The hard men with the guns are going to be the more likely actors in any political transition than those on the outside just talking. And therefore we needed to figure out how we could support them on the ground, better equip them…”

One of those “hard men”, of course, was the above mentioned Salim Idriss, the present “Defense Minister” of Syria’s nonexistent“provisional government” and de facto leader of the mercenary forces dispatched by Turkey into northern Syria this past week.

The truth is, however, the Kurdish side wasn’t much better. There never was a theological or ideological struggle between the YPG and Daesh, it was just a rivalry for a territory to be shared


of northern Syria among others.

At the beginning of the 2011 Arab Spring, Abdullah Öcalan rebuilt the PKK from his prison cell around a new ideology. After secret negotiations with NATO in the Imrali prison, he abandoned Marxist-Leninism in favor of a vague form of stateless communitarianism. So the Kurdish firebrand who had always struggled against Turkey in order to build his own state, Kurdistan, now claimed that any state is in itself a tool of oppression.

Then came a further double-cross. The aforementioned militants of the PKK, who had been forced to flee to the north of Syria after Öcalan’s capture, initially had adhered to his written pledge to Assad that his followers would never lay a claim to Syrian territory.

Indeed, at the beginning of Washington regime change warBreaking news

In the news

Watch as these ‘trustworthy’ broadcasters deliver the exact same script about where YOU should get your news! This is insane! The people of the United States are being manipulated every night by leftist-approved content… down to their very expressions! And, by the way… we’re not a democracy!

These people scoffed at President Trump’s diagnosis of a ‘stable genius.' They laughed at him and called him an idiot. But when they had to take the same test, the results are hilariously embarrassing. Check it out!


lacking either RirA, an iron limitation response regulator, or FadD \[[@CR25]\]. The *rirA* mutant's phenotype could be explained by the bacteria's ability to produce Rhb1021 under high iron conditions. However, the mechanism responsible for the iron-independent swarming phenotype shown by *fadD* mutants is unknown.

The connection between swarming motility and biofilm formation in *S. meliloti* has not yet been explored. In this work, we investigated whether factors known to influence swarming motility in *S. meliloti* have an impact on its capability to form biofilms. The study was performed using ExpR-deficient strains that display different surface motility behaviors. Although *expR*^−^ mutants are reported not to form the type of highly structured biofilms observed for *expR*^+^ strains, our findings show that, similar to flagella, Rhb1021 is required for both surface translocationMethods section.

Under our experimental conditions, all the different *S. meliloti* strains used in this study exhibited poor biofilm formation capabilities on PVC microtiter plates, making it difficult to discern any significant differences among treatments (data not shown). Therefore, we restricted our biofilm formation experiments to glass and plant surfaces.

The ability to develop biofilms on glass surfaces was examined by growing green fluorescent protein (GFP)*-*labelled *S. meliloti expR* mutant strains on chambered covered glass slides. Confocal imaging of GFP-labelled GR4 and Rm1021 strains was performed during a 10-day-long experiment to observe the three-dimensional structure of the biofilms developed by these two strains. By 3 days post-inoculation (dpi), both Rm1021 and GR4 developed the unstructured, flat biofilms characteristic of static cultures of *expR* mutant strains (Figure [1](#Fig1){ref-type="fig"}A) \[[@CR18]\]. Biofilm thickness increased with


availability \[[@CR30]-[@CR32]\]. Previous studies from our group showed that high concentrations of iron inhibit surface motility in *S. meliloti* reference strain Rm1021 \[[@CR25]\]. To investigate whether iron could also affect the development of surface-associated communities in the two *S. meliloti* strains, we compared the biofilms formed by the ExpR defective strains GR4 and Rm1021 on glass under high iron conditions (MM containing 220 μM FeCl~3~, herein referred to as MMh; i.e. iron-rich conditions that block siderophore production in Rm1021 \[[@CR25]\]), with those formed under low iron levels (22 μM FeCl~3~, referred to as MM. The latter conditions allow siderophore production in Rm1021 \[[@CR25]\]). The presence of high iron did not lead to any significant effect on the growth curves shown by liquid cultures of Rm1021 and GR4 (data not shown).the development of the characteristic sponge-like structure of biofilms formed under iron-replete conditions. Comparisons of biofilms are made relative to the corresponding parent strain.

The part that siderophore Rhb1021 in *S. meliloti* plays in biofilm development is indicated from the phenotype shown by *rhb* mutants on glass surfaces. Regardless of iron levels, these mutants formed thinner biofilms than the parent strain (Figure [2](#Fig2){ref-type="fig"}B; Figure [5](#Fig5){ref-type="fig"} A and [5](#Fig5){ref-type="fig"}B). The mechanism(s) by which Rhb1021 contributes to biofilm formation in *S. meliloti* have not been investigated, but in other bacteria, siderophores are implicated in biofilm development. The mechanisms whereby most of these siderophores act in establishing surface-associated bacterial communities are related to the important regulatory function that intracellular iron plays in biofilm formation in different bacteria. For example, in *Pseudomonas aeruginosa,* the pyoverdine


molecules with surfactant activities that are involved in swarming motility such as lipopeptides or rhamnolipids produced by *P. aeruginosa*, have been shown to influence bacterial biofilms by having different functions at different stages of biofilm development \[[@CR38]-[@CR42]\]. Another non-excluding possibility is that Rhb1021 contributes to surface-associated phenotypes by acting as a signal molecule, a function that has been reported for other siderophores and surfactants \[[@CR43],[@CR44]\]. In either case, the production of Rhb1021 within the biofilm must be tightly regulated to allow for normal biofilm development because exogenous application of purified siderophore to the *rhb* mutant not only does not rescue biofilm formation, but also significantly decreases biofilm formation in the parent strain (data not shown, \[[@CR34]\]). Further investigations will be necessary to elucidate the mechanism(s) of action ofof fatty acid-related compounds acting as biosurfactants and/or signal molecules deserves further investigation.

Although it is accepted that biofilm formation allows rhizobia to survive under adverse environmental conditions, the exact function of biofilms in the *Rhizobium*-legume symbiosis remains elusive \[[@CR20]\]. Recently, studies of a *nodD1* mutant and a quorum sensing-defective strain demonstrated that biofilm formation is crucial for optimal root colonization and symbiosis between *Sinorhizobium fredii* and soybean plants \[[@CR56]\]. Our data also support the importance of biofilm formation in promoting an effective symbiosis with the legume host. Although able to initiate nitrogen-fixing nodules, the strains used in this study had been earlier described as being less competitive in nodule formation, and here were found to be less efficient in biofilm formation. This is true for Rm1021 *vs* GR4


aim for driver-partners to have the best customer experience enhanced by solid processes, well-trained experts, and cutting-edge technology,” said Uber GM for Sub-Saharan Africa, Alon Lits. ”

“We are proud to say that on average, 90% of driver-partner issues are resolved within their first visit.”

MyBroadband visited the Uber Greenlight Hub in Johannesburg, with photos of the new building below.

Uber Greenlight Huband Nur77 expression was measured through a Western blot analysis. The data from each group are presented as the means ± SEs (n = 3). \*\**P* \< 0.01. (**B**) Nur77 overexpression decreased the palmitate-induced mRNA expression of PPARγ and its target genes (G0S2, GPR81, GPR109A, and Adipoq). mRNA expression was measured by a quantitative PCR analysis. The data from each group are presented as the means ± SEs (n = 3). \**P* \< 0.05, \*\**P* \< 0.01. (**C**) Nur77 overexpression decreased the palmitate-induced protein expression of PPARγ and G0S2. Protein expression was measured through a Western blot analysis. The data from each group are presented as the means ± SEs (n = 3). \*\**P* \< 0.01.

Nur77 attenuated lipid accumulation and augmented lipolysis in palmitate-treated HepG2 cells {#Sec6}
--------------------------------------------------------------------------------------------

Because Nur77 has been associated with hepatic steatosis^[@CR24]^, we also investigated the effects of Nur77 on lipid accumulation and lipolysis in palmitate-treated