categorization, you get All, Unread and Drafts, which is sufficient enough for browsing through the conversations on your Android phone. An interesting aspect of SMS management is that you can export and import all messages as either XML, TXT or XLS, and even include messages as part of the device backup. One bug that we encountered here was that ALL messages are always exported or imported, and there’s no way to selectively backup individual threads, despite selection checkboxes next to each message.

Did I mention that you can even reply to messages using Moborobo? When you do that, the status of the message will always keep saying “Sending”, despite the fact that it gets sent, and you will be able to verify that if you refresh the view forrestart the whole process. Once the XML is generated, switch to your desired Android device.

Once your Android is connected, head back to the Data tab, and this time, select the Import & Export > Import > Import from PC option.

Navigate to the XML you created earlier and select it. The application will take a while to load and import all the messages (depending on how many you have in the backup), and once completed, you’ll have all your iPhone’s SMS threads, by contact, imported to your Android. It’s that simple!

Similar process can be adopted for Contacts, and you can even create new contacts on iOS devices as well as Android. It’s worth pointing out that Moborobo does not offer message management for iPad as of yet.

Final Words

That pretty


of dry solids in the waste liquor to 65-85%, and even higher, combustion of thus obtained strong waste liquor in the chemical recovery boiler, recovery of chemicals released and regenerated in connection with the combustion and processing of said chemicals for further chemical pulp production. In older production plants the dry-solids content of waste liquor may have remained below 65%, which complicates efficient combustion of waste liquor and chemical recovery. The sum of the mass fractions of the dry-solids content and the water in the waste liquor entering the combustion is very near to 100%.
In waste liquor combustion, the waste liquor is injected in form of droplets into a furnace, where the liquor droplets dry, pyrolyze, mix with oxygen carriers and burn. Oxygen carriers include oxygen, water vapormechanism. Furthermore, the SUN2 protein can form different assemblies, including homodimers and heterodimers with SUN1. Finally, we provide evidence indicating that SUN1 and SUN2 may form a physical interaction between the nuclear envelope and the centrosome.


doesn't pick up on the job.
In a more distributed scenario with message queues the problem is harder and potentially unsolvable. In order to prevent double processing you need some sort of shared lock, but the distributed architecture is specifically designed to avoid that kind of lock.
You can either have a single routing service, simple enough that it doesn't need to be horizontally scaled, which pulls jobs and assigns them to individual workers.
Or Segment the workers to avoid the possibility of duplication, say have one worker for email starting A, another for B etc
Or simply accept a low duplication possibility. After all most forms of queue or distributed DB will have some attempt at preventing it. You are probably only looking at edge cases where a duplicate messageAim 1: Enhancement of the Microscope and its Computer Control The objective of this core TR&D project is to develop and improve EM techniques for image contrast enhancement and 3D information extraction from biological specimens, particularly thick sections, with computer-controlled specimen positioning, electron optics and a use of a direct digital readout image acquisition system being developed under a separate subproject (see following project description). Progress has been made in the following areas: Computer control and microscope automation: A microscope control library has been established and new routines are added as need arises. All optical parameters and most mechanical controls (such as the four axes of the stage) can now be remotely controlled by a local host as well as by workstations linked to the host by the


accepts children, 6 through 17. The facility has been increasingly accepting children 8 and under.

But Ank said most of the kids, particularly the younger ones, have severe behavioral issues that require multiple staff to manage.

“Treatment homes are so hard to find across the state, period. I don’t see how we’re going to establish six in this county,” Ank said.

Swan said everyone needs to stay positive.that include fenestrations have several disadvantages. For example, if a medical drape includes more than one fenestration, not all of which are being used for inserting a catheter, the area of the patient's body adjacent the unused fenestration(s) remains unnecessarily exposed during the procedure. Thus, bodily fluids and/or other surgical fluids that may contain microorganisms may contact the exposed area of the patient's body through the unused fenestration(s) and possibly lead to infection.
Moreover, existing medical drapes having fenestrations only provide access to one area (for example, the subclavian area) of the body. Thus, more than one drape may be required for procedures that require a catheter to be inserted into multiple areas of the patient's body (for example, the subclavian area and the brachial area). Utilizing multiple drapes


the space time is given by $$ds^2=A^2\frac{(1-k\alpha)^2}{(1+k\alpha)^2}dt^2-\frac{(1+k\alpha)^4}{1+\frac{r^2}{R^2}}(dr^2+r^2(d\theta^2+sin^2\theta d\phi^2))$$ where, $\alpha(r)$ is given by eq.(10). Hence the geometry of the 3 space obtained at $t=constant$ section of the space time of metric (12) is a deviation introduced in spherical 3 space and the parameter $k$ is a geometrical parameter measuring inhomogenity of the physical space. With $k=0$, the space time metric (12) degenerates into that of Einstein’s static universe which is filled with matter of uniform density. The space time metric of Pant and Sah [@ps] is a generalization of the Buchdahl solution, the physical 3-space associated with which has the same feature. For $\lambda=0$, the solution reduces to that obtained by Buchdahl which is an analog of a classical polytrope of index 5. However, for $\lambda>0$, the solutionshould be matched with the isotropic form of Schwarzschild exterior solution,i.e., $$e^{\frac{\nu}{2}}|_{r=b}=\left( \frac{1-\frac{m}{2b}}{1+\frac{m}{2b}}\right)\;\;\;\;\;\;\;  e^{\frac{\mu}{2}}|_{r=b}=\left(1+\frac{m}{2b}\right)^2$$

\(3) The physical radius of a star $r_o$, is determined knowing the radial distance where the pressure at the boundary vanishes (i.e., $p(r)=0$ at $r=b$). The physical radius is related to the radial distance ($r=b$) through the relation $r_o= b \left(1+ \frac{m}{2b} \right)^2$ [@jvn].

\(4) the ratio $\frac{m}{b}$ is determined using eqs. (9) and (16), which is given by $$\frac{m}{b} = 2 \left( \frac{1+k \alpha}{\sqrt{1+y^2}} -1 \right)$$

\(5) The density inside the star should be positive i.e., $\rho>0$.

\(6) Inside the star the stellar model should satisfy the condition, $dp/d\rho<1$ for the sound propagation to be causal.

The usual boundary conditions are that the first and second fundamental forms be continuous across the boundary $r=b$. Applying the boundary


Cytological evidence of defective template in the fragile X chromosome.
In cells of fragile X patients, the changed X segment may appear as a poorly staining region or a gap, or as a deletion, involving one or both chromatids. To find out whether the fragile site represents an incompletely replicated DNA sequence, as has been suggested recently, we analyzed the four chromatids of methotrexate-induced endoreduplicated fragile X chromosomes. Our main observations were: (1) a deleted chromatid was never internal to a poorly staining one; (2) an endoreduplicated X chromosome with a fragile site never included a normal chromatid. These results can be explained by assuming that DNA at the fragile site, when replicated in the presence of methotrexate, may undergo defective replication and give rise to improperly packaged chromatin,enforce the Voting Rights Act. “My staff and I consulted with Federal governmental components and inquired whether the Department of Justice would support, and if so would request, including of a citizenship question as consistent with and useful for enforcement of the Voting Rights Act,” Ross wrote.

Now, Freedom of Information Act documents have shown that not only did Ross speak with Steve Bannon about this, but that notorious racist (and current candidate for governor of Kansas) Kris Kobach was also there. The DOJ’s second supplemental response has this little walk down memory lane.

Mary Blanche Hankey, James McHenry, Gene Hamilton, Danielle Cutrona, John Gore, and Jefferson Sessions. Although Kris Kobach is not a "government official" within the meaning of the Supplemental Memorandum, the Defendants identify him nonetheless for the


(normal skin function).

Our focus of the past few articles has been on facial oils. Face and body oils are an incredible way to treat your skin to the vital nutrients, antioxidants, and omegas that it craves. Well cared for skin is likely to age more gracefully and appear more radiant. Your skin requires a healthy diet, sufficient hydration, ample sun protection, and high quality skincare products.

There are several components that are important when choosing the best face oil. Choosing oil that is rich in omega-3, omega-6, and or omega-9 can make a world of a difference in the long run of taking care of your precious skin. Most of these oils are commonly found in facial oil blends. Next week, we will talk a bit more about nutritionImmunology (CSACI), which is endorsed by Dietitians of Canada, does not recommend delaying any foods. "Parents don't need to delay the introduction of potential allergens like peanuts, fish or eggs," says Kate Comeau, registered dietitian and spokesperson for Dietitians of Canada. "Based on current evidence, delaying introduction will not reduce your child's risk of developing a food allergy."

Consistency of baby foodMany parents purée their baby's food until it is a well-blended blast of silky-smooth supper. A new joint recommendation from Health Canada, Dietitians of Canada, Canadian Paediatric Society and The Breastfeeding Committee for Canada, "Nutrition for Healthy Term Infants: Recommendations From Six to 24 Months," suggests parents introduce a variety of textures including lumpy, tender-cooked, finely minced, mashed, puréed and ground foods no later than nine months. "It


also have questions seeking help. If you have the information you are welcome to respond, but please ensure that the information so provided is genuine and not misleading.

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment.Full Disclaimerviability was determined with a Cell Counting Kit-8 assay. (E) A549 cells were treated with ALT (4 *µ*m) and/or GEM (25 *µ*m). NCI-H520 cells were treated with ALT (40 *µ*m) and/or GEM (25 *µ*m). After 24 h of incubation, morphological changes were visualized under an inverted light microscope. Magnification, ×200. Values are expressed as the mean ± standard deviation from three independent experiments. ^\*\*^P\<0.01, ^\*\*\*^P\<0.001 and ^\*\*\*\*^P\<0.0001 vs. control. ^++^P\<0.01 and ^++++^P\<0.0001 vs. GEM. ^\#\#\#^P\<0.001 vs. ALT. GEM, gemcitabine; ALT, alantolactone.

![](IJMM-44-03-1026-g00)

![](IJMM-44-03-1026-g01)

![Effects of ALT and/or GEM treatment on the cell cycle in lung cancer cells. A549 cells were treated with ALT (4 *µ*m) and/or GEM (25 *µ*m). NCI-H520 cells were treated with ALT (40 *µ*m) and/or GEM (25 *µ*m). (A) After 24 h of incubation, the cell cycle was


device using BRF. This was made along the 2 o'clock for anterior in the first case and 5 o'clock for posterior wall of the esophagus in the second case, 15 cm above the gastroesophageal junction (GEJ). The submucosal plane was entered and a submucosal tunnel was created (BRF, cutting frequency 400 kHz, power setting 35 W) by using Speedboat-RS2 for 2 cm beyond the GEJ. The endoscope was withdrawn into the esophageal lumen and entered the stomach, where a bluish submucosal hue in a retroflexed view confirmed the adequacy of the tunnel. This step was repeated (if necessary) while dissecting beyond the GEJ. The Sppedboat-RS2's novel design provided lateral and/or forward cutting using the curved tip, flat edges of the blade. Microwave coagulation (frequency 5.8 GHz, power setting 10 W) was used tovessels traditionally has been achieved by using monopolar current (high voltage 2000V) which has potential for resulting in deep burns causing mucosal perforation. The Speedboat-RS2, in contrast, uses bipolar RF (low voltage 200V) for large vessels, which is associated with minimal risk of deep burns and helps with rapid tissue healing [@JR1825-6] [@OR1825-10] . The device is boat-shaped and has curved bipolar electrodes on the sides. When current flows through the tissue between the two electrodes, the cutting effect is restricted to the needle electrode. When an incision is made, tissue damage is restricted to this small region. The power requirements are lower because the current is limited to the small piece of tissue between the active electrodes, which results in more predictable tissue modification [@OR1825-10] . Although


or fellowship will find it much easier to use Speedboat RS2 for third space endoscopy as the device may reduce the overall risk and potential complications associated with these procedures. The small sample size is a limitation of our study, however, looking at the promising results with the device, we believe such anecdotal innovative cases lay a platform for developing future studies.

Conclusion
==========

To conclude, early experience shows that use of the Speedboat-RS2 to perform POEM is feasible and it has a good safety profile and precision. Submucosal tunneling with the device was done relatively quickly and coagulation was effective. Long-term studies with a larger patient cohort are warranted.

**Competing interests** The authors declare that they have no conflict of interest.
have, the faster you kill.

But is it a better Modern deck? I’m not sure. The aggro boost comes at a cost which may not be worthwhile. The problem comes from the sacrifices necessary to play green: my deck, and many others, struggle with the color requirements.

In other versions, you only really need blue mana. UW can survive without white because we only use it for sideboard cards and Path to Exile. UG consistently needs green, meaning accepting a vulnerability to Blood Moon. This normally isn’t a problem, as mana denial is weak against aggressive decks (especially ones with Aether Vial). However, you can never fully rely on Vial, and the more non-basics you play, the higher the risk that hate will be effective and worthwhile. I have been


a Steam copy, we weren’t able to get connected. Rather a disappointment, I must say, as I’ve had all this practice now and was looking forward to kicking his ass for once. :(

Overall though I enjoyed Majesty 2 a great deal. Despite its somewhat repetitive nature, it’s charming and fun and even after playing 25 hours or so of campaign, I’m still looking forward to starting on the expansions – which has to be a good sign!
Important New Browser Updates to Know (For Better Results) - dcuttridge1
https://medium.com/@danielcuttridge/how-browser-updates-are-changing-the-online-landscape-and-why-you-should-care-77cf5b0ff096
======
dcuttridge1
Want to know how to avoid disaster and simultaneously get a leg-up on your
websites competitors?

Then you need to be paying attention to browser updates.


Microphthalmos with cyst: a clinical study.
Defects in closure of embryonic fissure and invagination of optic vesicle results in varied clinical presentation of microphthalmos with cyst. In our study, three patients had microphthalmos with cyst in one of their orbits. The cyst presented either as a swelling in the lower lid or as a sinus with purulent discharge associated with absent or small sized eyeball. The microphthalmic eye showed a spectrum of posterior segment abnormalities such as retinal disorganisation, gliosis, choroidal, and scleral coloboma. Microscopically, the cyst connected to the coloboma consisted of an outer layer of fibrovascular tissue and an inner gliotic neuroectodermal layer. The treatment consisted of excision of cyst alone or of microphthalmic eye with cyst. The use of conformers was mandatory after removal of cysticstating that 99.9% of queer people who attempted to change their sexuality at the organization never became straight.

What's more, according to a damning report by the American Psychological Association, participants of conversion therapy note higher rates of mental health issues, ranging from PTSD, to anxiety, to depression and suicide. That means this practice is actively harmful to an already vulnerable community.

"Few practices hurt LGBT youth more than attempts to change their sexual orientation or gender identity through so-called conversion therapy," writes the National Center for Lesbian Rights (NCLR).

It's time to follow New Jersey's lead: Despite the closing of Exodus International in 2013, anti-LGBT religious groups are still too often keen on "changing" LGBT people from queer to straight, and conversion therapy continues to be marketed as a viable


was particularly loud or out of order. But even with my headphones on, it distracted me from what I was trying to do.

I often escape to coffee shops to work, and while I tried that this time, I still often found it hard to get back into a working rhythm after all the stop start.

As I look at our new kitchen, it’s been completely worth it. But I do feel my work has suffered.

Working from home can make life a lot easier. But with it comes a set of new challenges. Even after five years, I’m still learning to navigate them.

Don’t worry, I’m not going to break into Ella Fitzgerald (although I do love that song).

The ‘at last’ instead refers to the new version of this site. It’sAnti-CENP-B antibodies are associated with prolonged survival in breast cancer.
Presence of a relationship between autoimmunity and malignant diseases has been investigated for a long time. Anti-SS-B and anti-centromere protein (CENP)-B antibodies are used as serologic markers for autoimmune diseases. In this study, these autoantibodies were studied in breast cancer patients, and their effect on survival was evaluated. Breast cancer patients treated between January and June 2003 were prospectively included in this study. Antibodies were studied by ELISA, and serum values of greater than 10 U/ml were accepted as positive. In total, 55 patients with breast cancer were prospectively included in the study. Median follow-up time was 62 months. In univariate analysis, estrogen receptor status, anti-CENP-B antibody status and tumor size significantly affected disease-free survival, whereas overall survival was


many online sites, the public key becomes a new form of personally-identifying information. The public key can be thought of as a string of bytes that can be used as a “database key” in addition to being a cryptographic key. In this context, a public key can be employed to correlate and track a user's online activities across multiple online resources. For example, two web sites could compare the public keys registered at their sites, and, finding matches, could correlate the purchasing profiles of the owners of those keys in ways a user did not contemplate or sanction.
In addition, although a user will typically want to preserve his or her privacy when conducting online transactions, there are situations in which the user may want to allow web sitesText+ Modifier – Follower

The ‘Follower’ is a modifier that only works with the Text+ tool to create interesting motion graphic text animations. It is fairly easy to use although you need to know a few things to get it to work.

NOTE: If you find this tutorial helpful and would like to have it on your own site or blog, click on the ‘dailymotion’ logo in the bottom right corner of the video preview and then on the Dailymotion.com site below the video look for the ‘Share’ option and ‘Get embed code’ and copy and paste that to your site.


attacks. Essentially, a DoS attack disrupts or completely denies services to legitimate users, networks, systems or other resources. The intent of such attacks is usually malicious and often takes little skill or resources because the requisite tools are readily available.
In the case of TCP/IP, attacks normally focus on the way systems handle handshaking and connection initiation. FIG. 1 is a schematic diagram of a data communications system using the normal 3-way handshaking used in TCP to process connection requests.
A SYN packet is sent from a specific port on a source 10 to the same port at a destination 20. Upon receipt of the SYN packet, the destination 20 then sends an SYN/ACK packet to the source 10. Upon receipt of the SYN/ACK packet, the source 10 then sendsan ACK packet to the destination 20 and the connection is then considered established (also referred to as open). Data can then be communicated between the source 10 and destination 20.
The packets discussed above have a predetermined format, as is defined in RFC0793 available from ftp://ftp.rfc-editor.org/in-notes/rfc793.txt, and is incorporated herein by reference.
One such DoS attack is referred to as an SYN flood attack. While the standard 3-way handshake works well most of the time, most systems have only a finite number of resources available for setting up connections and potential. While most systems can sustain hundreds of concurrent connections to a specific port, it may only take a dozen or so potential connection requests to exhaust all resources allocated to setting up connections. It is this weakness that


13 at t0, is associated with a given instant t0, 10. The generic approach to detection known from the prior art requires a memory of fairly significant size. Assuming that each of the values of the function representative of the score v is stored on a double, that is to say on 8 bytes, then, according to the generic method of the prior art, the quantity required to store v is the product of eight and the number of interesting event types (Ne), the number of detectable micro-events (M), the temporal domain of the votes, that is to say Ne*M*(2d+1), where d is the half-size of the temporal domain over which the observation is looked at. Moreover, the propagation of the information requires Ne*(2d+1) operations of addition andfor my eyes so if you can, buy the Freshlook One Day coloured contacts as they are a bit smaller and the colours are just as noticeable.

I have Hazel eyes and have purchased a few times now the Saphire Blue eyes! I have noticably blue eyes when I wear them and have been complimented loads on them! I was even told by a female friend my eyes were hypnotic! Can't wait to order more! They are comfy and last and I trust this site with all my orders which is why every month I order from them as fast reliable and if there has been a problem with the batch the customer service has been impeckable and above and beyond

Hola! Recientemente compre los lentes de color "Sterling Grey"


about 3 inches away from my face. I ordered these as I concluded they looked the lightest shade of brown available, so basically they don't have a genuine/striking light brown shade available. Could for better on blue eyed people though!
TRUE SAPPHIRE: I thought sterling grey was my favourite shade of blue as its the lightest and thought it would show up the best BUT this is my new favourite blue. It's still light blue, just more realistic and brighter. I've had the most compliments from these. In fact, about 8 in the past 3 weeks.
I've never been a huge fan of green eyes, but I'm tempted by gemstone green or the actual grey ones to have a change from blue and brown.
I'm not impressed by the slight riseThe heavy syllables of the victims' names boomed out along the streets around Ground Zero. The public were patted down, then allowed up a cramped side road to peer at a distant video screen of the memorial. They filmed the video screen on their mobile phones, filmed each other filming, and film crews filmed them filming.

Filming crowd. Photograph: Charlie Skelton

It was hardly fertile ground for grief, you'd think. And yet, the weird detachment of the moment was severed by the chanting of the names and the brief tributes of the readers. It was the daughter who said her father's friends tell her that she reminds them of him that did it for me. That, and the list of victims called Jones. Jones after Jones after Jones. Too many


Antimicrobial resistance and association with class 1 integrons in Escherichia coli isolated from turkey meat products.
The objective of this study was to quantify the role of class 1 integrons in antimicrobial resistance in Escherichia coli isolated from turkey meat products purchased from retail outlets in the Midwestern United States. Of 242 E. coli isolates, 41.3% (102 of 242) tested positive for class 1 integrons. A significant association was shown between presence of class 1 integrons in E. coli isolates and the resistance to tetracycline, ampicillin, streptomycin, gentamicin, sulfisoxazole, and trimethoprim-sulfamethoxazole. Attributable risk analysis revealed that for every 100 E. coli isolates carrying class 1 integrons, resistance was demonstrated for ampicillin (22%), gentamycin (48%), streptomycin (29%), sulfisoxazole (40%), trimethoprim-sulfamethoxazole (7%), and tetracycline (26%). Non-integron-related antimicrobial resistance was demonstrated forStates, while lauding the lower prices — but not the quality — of that available in the Soviet Union. Then, at a banquet attended by about 100 people, Sanders blasted the way the United States had intervened in other countries, stunning one of those who had accompanied him.

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“I got really upset and walked out,” said David F. Kelley, who had helped arrange the trip and was the only Republican in Sanders’s entourage. “When you are a critic of your country, you can say anything you want on home soil. At that point, the Cold War wasn’t over, the arms race wasn’t over, and I just wasn’t comfortable with it.”

Sanders declined to be interviewed for this report. Jeff Weaver, his senior adviser, said the trip fits into Sanders’s effort


much notice. He got married before a crowd of hundreds in Burlington. “On the next day we began a quiet, romantic honeymoon,” Sanders wrote in his book “Outsider in the White House,” jocularly describing the journey with his bride, Jane, and about 10 others.

“It cost him some political capital when you are self-identified as a socialist and you go to the Soviet Union,” said Terrill G. Bouricius, who accompanied Sanders as a Burlington City Council member. “We knew there would be some negative effects of that, but we thought pushing peaceful coexistence was important.”

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The trip had its genesis a year earlier, when Kelley helped arrange for a Soviet choir of about 30 girls to visit Burlington. After staying with local families and visiting schools, the choir performed forhad for the Soviet Union.

“I did not see a hungry child. I did not see any homeless people,” Sanders told the Burlington Free Press. While Cuba was “not a perfect society,” he said, the country “not only has free health care but very high-quality health care . . . The revolution there is far deeper and more profound than I understood it to be. It really is a revolution in terms of values.”


One man stood up during the event's Q&A portion, expressing concern about climate change. Addressing it, the audience member said, should be an imperative to Christians commanded by the Bible to be stewards of the Earth.

"I always have problems when people come up and say the science is settled," said Santorum, a Republican presidential candidate and winner of the 2012 Iowa caucuses. "That's what they said about the world being flat. When someone says the science is settled you're not a scientist, because scientists never say the science is settled."

He added: "The idea that the science is settled, to me, tells me that this is political science, not real science."need to write duplicate code, and we don’t have pages coupled to other pages.

Final Thoughts

Separating your state from your views creates a much cleaner and scalable architecture. If at all possible, this anti-pattern of coupling your state to your views should be avoided.


delivered to our apartment together with all of her stuff – so I decided, now that I own it, hell, why not give it a shot.

Good, light-hearted and very instructive reading for novel wine enthusiasts, much much better than the widely available Wine Folly book by Madeline Puckette, which some mistakenly buy and believe to be a good reference guide. Less colorful charts and hellava more sense here.

Jancis Robinson, a revered wine expert and a very harsh wine critic, explains it all in short, punchy, and self-explanatory language. The bare minimum of what everyone should know about wine, its production, bottling, how to taste it, common grape varieties, major wine regions, stemware, corkscrews, Coravin, decanting, aging, useful lingo, shop and restaurant tips, all in a hundred tiny A5-likewant a solution for the Elliott State Forest that protects its remarkable wildlife habitat and keeps it in public ownership.

Background

The forest was created in 1930 to provide long-term funding for Oregon’s public schools and is managed by the Oregon Department of Forestry. Decades of unsustainable logging, and shift in social acceptance of clearcutting old growth forests, the Elliott is now caught up in a conflict between its historic and out-of-date tie to the Oregon Common School Fund and logging proceeds, and the Oregon public’s desire to protect our remaining old growth forests, wild salmon, and wildlife.

Despite this new reality, state officials adopted a Forest Management Plan at the end of 2011 that increased clearcutting and nearly doubled the annual harvest rate within the Elliott State Forest. In 2012,


and to find a solution for the Elliott that keeps it permanently in public ownership and protects its natural resources. Urge them to go back to the drawing board and, through the legislature, transfer the Elliott into a Trust Land, keeping the forest in state ownership.

Click here to learn more about the history of the Elliott and the importance of its habitat for imperiled species.

Updates

December 13, 2016: After more than 200 state forest supporters and conservation groups rallied at the State Land Board hearing to oppose the proposed sale of the Elliott State Forest, Governor Brown temporarily removed the Elliott from the chopping block. While the Land Board did not outright reject the Lone Rock Timber Company Privatization Proposal, they did take a significant step in the rightdeconstructive massing,
achieving significant new results.?
http://www.greatbuildings.com/architects/Frank_Gehry.html
Certainly the adjectives ?sculptural,? ?exploded? and ?deconstructed?
are all terms that can be validly applied to the Guggenheim Bilboa.
Its seemingly chaotic mingling of forms expresses for many the quality
of modern life. Yet out of all of this chaos emerges a harmony of a
new kind.
*********************
MATERIALS
The third part of your question has to do with ?materials and attitudes?.
It?s interesting to note that this very modern building relied on very
modern technology to be realized. Although the design work itself was
not computer-assisted (Gehry used traditional physical modeling),
computer assistance was needed to fabricate the titanium panels that
clad much of the building?s steel structure and with the other many
technical challenges of this construction project. A French software
program called CAITA, used in the construction of airplanes, made
possible the highly precise fabrication of


the panels.
This site-- http://www.culturevulture.net/ArtandArch/Bilbao.htm-- has
an excellent account of this aspect of the building: ?Composed of a
group of free flowing volumes that seem to have met in a train crash,
the building shows sections of its steel skeleton, but mostly is
clothed in tissue-paper thin titanium (from whence the startlingly
beautiful effects of reflected light, the source of the welcoming
gleam from afar), warm limestone, and glass. From the three main
materials, paneling of unique sizes and shapes (details generated from
computer design, manufactured by computer commanded robots) was
created, thus allowing for the organically irregular and curved shapes
of the mass. It's like a mutated kind of shingling, taking that
technique to places it has never been before. (Critic Paul Goldberger
noted that changes in architecture have already moved ahead of Gehry;
while Gehry designs in his head andexternal complex appearance of the architectural
shapes, there lies a neat, clear world where it is easy to find one's
way around.?
http://www.guggenheim-bilbao.es/ingles/home.htm
Here is what another commentator has to say about the interior
organization and flow of the building: ?The interior organization
returns the visitor to the central atrium over and over again. From
this space the visitor can see back to the main entrance as well as
out to the river. While the galleries provide an appropriate mix of
exotic spaces and more traditional ones, they are containers for art -
that is, closed and inward looking. But the transition from gallery to
gallery or floor to floor always returns to the atrium space. Here,
you are immediately re-oriented within the building. Equally
important, the city becomes part of the permanent exhibit, yet forever
changing with time and light.?
http://www.architectsonline.com/publications/bilbao/
And here


expresses for many the quality
of modern life. Yet out of all of this chaos emerges a harmony of a
new kind.
*********************
3. The third part of your question has to do with ?materials and attitudes?.
It?s interesting to note that this very modern building relied on very
modern technology to be realized. Although the design work itself was
not computer-assisted?Gehry used traditional physical
modeling--computer assistance was needed to fabricate the titanium
panels that clad much of the building?s steel structure. A French
software program called CAITA, used in the construction of airplanes,
made possible the highly precise fabrication of the panels.
This site-- http://www.culturevulture.net/ArtandArch/Bilbao.htm-- has
an excellent account of this aspect of the building: ?Composed of a
group of free flowing volumes that seem to have met in a train crash,
the building shows sections of its steel skeleton, but mostlyto the
main entrance; the idea was to bring the city right to the doors of
the building. A broad flight of steps takes pedestrians down to the
Museum hall although descending flights of stairs are not a frequent
feature of institutional buildings. This is an inspired response to
the differences in height between the level of the river and the level
of the city center. It also enables a building with a surface area of
24,000 square meters and more than 50 meters high to be slotted into
the city landscape without it towering over the neighboring
buildings.?
The Wilkepedia entry agrees with this assessment: ?Also important is
while the museum is a spectacular monument from the river, on street
level it is quite modest and does not overwhelm its traditional
surroundings.?
http://en.wikipedia.org/wiki/Guggenheim_Museum_Bilbao
Go to this image bank address in order to


crossing the Nervion
(also known as the Bilboa river).
Let me take the parts of your question in the order you presented them.
1. The site.
The museum is located in central Bilboa in a riverside area formerly
dedicated to warehousing and port activities. (The port of Bilboa is
now located directly on the Bay of Biscay.) The building is approached
from its eastern end, where the size of the building (it is VERY
large: 24,000 square meters on a site of 32,500 square meters) is not
so apparent. The design seeks not to overwhelm its historic
surroundings and the way it avoids doing this is well described in The
Museum?s own website: http://www.guggenheim-bilbao.es/ingles/home.htm
?People coming from the calle Iparraguirre, one of the main streets
bisecting the center of Bilbao diagonally, are led directly to the
main entrance; the idea was tooutside. But the Museum?s own website says that one can see from
the outside how the building is composed of two kinds of galleries.
The building has a total of 19 galleries organized around the central
atrium. ?Ten of these galleries have an almost classical orthogonal
look and can be identified from outside by their stone finishes. Nine
other, irregularly-shaped galleries present a remarkable contrast, and
can be identified from outside by their unusual architecture and the
covering of titanium.?
The biggest gallery is 130 meters long (!). It is ?free of columns and
with flooring specially prepared to cope with the comings and going of
visitors and museum staff, as well as the sheer weight of the works on
display there. Seen from the outside, this gallery slides underneath
the Puente de La Salve and runs up against the


person. Perhaps I will run into you there!
Scribe_ga
An enormously complex structure, the Guggenheim Museum in Bilboa is
also a very complex subject, but I hope that my answer will at least
give you a good start on comprehending and appreciating this building,
which seems to be considered one of the great buildings of the 20th
Century, by almost global consensus.
First, a little about the city in which it is located. Bilboa is an
industrial port city in the Basque country of Spain. The ?river? on
which the building is located (the Nervion) is actually an estuary of
the Atlantic. Bilboa is a medium-size city (350,000 population) and
the largest in the Basque region of Spain. Both city and region must
have visionary leadership. Not only did they succeed in persuading the
Guggenheim to locate a ?branch? there, butpaneling of unique sizes and shapes (details generated from
computer design, manufactured by computer commanded robots) was
created, thus allowing for the organically irregular and curved shapes
of the mass. It's like a mutated kind of shingling, taking that
technique to places it has never been before. (Critic Paul Goldberger
noted that changes in architecture have already moved ahead of Gehry;
while Gehry designs in his head and implements with the computer, a
new generation has adopted the computer itself as the generator of
design. Still, Gehry's work could not be implemented without the use
of computers.)?
The reflective nature of the skin of the building contributes in no
small part to the beauty of the building, in all kinds of light, even
the under the frequently grey skies of this city by the Atlantic.
4. Symbolic and historic association of


site.
The museum is located in central Bilboa in a riverside area formerly
dedicated to warehousing and port activities. (The port of Bilboa is
now located directly on the Bay of Biscay.) The building is approached
from its eastern end, where the size of the building (it is VERY
large: 24,000 square meters on a site of 32,500 square meters) is not
so apparent. The design seeks not to overwhelm its historic
surroundings and the way it avoids doing this is well described in The
Museum?s own website: http://www.guggenheim-bilbao.es/ingles/home.htm
?People coming from the calle Iparraguirre, one of the main streets
bisecting the center of Bilbao diagonally, are led directly to the
main entrance; the idea was to bring the city right to the doors of
the building. A broad flight of steps takes pedestrians down to the
Museum hall although descendingexplored the classical architecture themes. In these works
he melds formal compositions with an exploded aesthetic. Most
recently, Gehry has combined sensous curving forms with complex
deconstructive massing, achieving significant new results.?
Certainly the adjectives ?sculptural,? ?exploded? and ?deconstructed?
are all terms that can be validly applied to the Guggenheim Bilboa.
The seemingly chaotic mingling of forms expresses for many the quality
of modern life. Yet out of all of this chaos emerges a harmony of a
new kind.
Materials and attitudes
It?s interesting to note that this very modern building relied on very
modern technology to be realized. Although the design work itself was
not computer-assisted?Gehry used traditional physical
modeling--computer assistance was needed to fabricate the titanium
panels that clad much of the building?s steel structure. A French
software program called CAITA, used in the construction of airplanes,
made possible the highly precise


relationship to the site. To the
right is the plaza and main entrance, to the left is the Puente de la
Salve which as the Museum?s website says actually ?pierces? the site
and whioch is integrated into it by the ?sculptural tower,? and a
broad staircase leading up to it: ?The broad flight of stairs that
goes up to the sculptural tower, conceived as a device to absorb and
integrate the Puente de La Salve into the overall architectural scheme
of the building, is also a public access way that connects pedestrians
with the rest of the city.?
This site has two good images:
http://www.nanis-reiseseiten.de/Spanien/page_1.html
1. A helpful from-the-river image that shows that ?broad flight of
stairs? and the very beautiful pedestrian esplanade that curves
between the riverbank and a moat-like expanse of water overlooked by a
pavilion, and
2. The same, butcity and region must
have visionary leadership. Not only did they succeed in persuading the
Guggenheim to locate a ?branch? there, but the leadership endorsed and
supported the daring vision of the museum and its architect for a
building that would be as startlingly and radically different as was
the Guggenheim?s home museum in New York City, designed by Frank Lloyd
Wright., in the 1950s. Certainly the city?s boldness has been
vindicated. It has been a major factor in the economic revival of the
city, both because of tourist dollars attracted to the city as never
before and because of the new fame, status, and cachet the building
has given to a rather obscure and economically-depressed Spanish city
located in a region that in for many years has been bedeviled by a
violent separatist movement. Incidentally, the city has continued


building is composed of two kinds of galleries.
The building has a total of 19 galleries organized around the central
atrium. ?Ten of these galleries have an almost classical orthogonal
look and can be identified from outside by their stone finishes. Nine
other, irregularly-shaped galleries present a remarkable contrast, and
can be identified from outside by their unusual architecture and the
covering of titanium.?
The biggest gallery is 130 meters long (!). It is ?free of columns and
with flooring specially prepared to cope with the comings and going of
visitors and museum staff, as well as the sheer weight of the works on
display there. Seen from the outside, this gallery slides underneath
the Puente de La Salve and runs up against the end of the tower that
embraces the bridge and brings it into the building.? It isneeded to fabricate the titanium
panels that clad much of the building?s steel structure. A French
software program called CAITA, used in the construction of airplanes,
made possible the highly precise fabrication of the panels.
This site-- http://www.culturevulture.net/ArtandArch/Bilbao.htm-- has
an excellent account of this aspect of the building: ?Composed of a
group of free flowing volumes that seem to have met in a train crash,
the building shows sections of its steel skeleton, but mostly is
clothed in tissue-paper thin titanium (from whence the startlingly
beautiful effects of reflected light, the source of the welcoming
gleam from afar), warm limestone, and glass. From the three main
materials, paneling of unique sizes and shapes (details generated from
computer design, manufactured by computer commanded robots) was
created, thus allowing for the organically irregular and curved shapes
of the mass. It's like a mutated kind


activated oxidase stress could then further enhance the LOX-1 level \[[@R30]\]. Previously, we found that oxidative stress causes LOX-1 up-regulation through NADPH oxidase activation \[[@R31]\]. In Figure [5](#F5){ref-type="fig"}, we found that the pre-treatment of metformin can reduce oxLDL-induced LOX-1 up-regulation. However, this phenomenon was reversed by both siSIRT1 and siAMPKα. DCHC, AICAR, Ro32-0432 and Apocynin also significantly reduced oxLDL-caused LOX-1 over-expression. Thus, we suggested that metformin protects against oxLDL-induced LOX-1 up-regulation involving the SIRT1/AMPKα/PKCα/NADPH oxidase pathway. This hypothesis was also supported by employing the LOX-1 promoter assay (Figure [5C](#F5){ref-type="fig"}).

![Metformin protects against oxLDL-induced LOX-1 up-regulation\
HUVECs were pretreated with metformin for 2 hrs, followed by exposure to oxLDL (150 μg/mL) for another 24 hrs. At the end of the incubation period, cells were lysed and SIRT1 protein were analyzed byelucidated the probable mechanism whereby metformin protects against the oxLDL-induced human endothelial dysfunction. In this present study, we successfully revealed that the metformin pre-treatment attenuates oxLDL-caused endothelial apoptosis. Metformin enhanced SIRT1 expression in both protein and mRNA levels and promoted phosphorylation of AMPK, thereby contributing the potent protective abilities against oxidative injuries. The signaling pathways of metformin-mediated anti-atherosclerotic effects involve inhibit the NADPH oxidase activity as well as the ROS formation, which therefore mitigates the LOX-1 up-regulation and AKT/eNOS deactivation. In addition, metformin suppressed both Ca^2+^ elevation and mitochondrial dysfunction by the oxLDL induction in the human endothelial cells.

Furthermore, SIRT1 is recognized as a novel target for prohibiting the early stage atherosclerosis in the human endothelial cells. The SIRT1 gene is a member of nicotinamide adenine dinucleotide (NAD)-dependent


Holly Bass

Holly Bass (born June 23, 1975) is a Washington DC-based performance artist, poet, dancer, arts educator and cultural activist.

Work
Her movement and spoken-word pieces reveal a fascination with "objectification, observation, and the commodification of art and of the body." Holly has performed across the US and internationally. Her poems, essays and articles have been published in numerous publications including the Wall Street Journal, The Washington Post, Callaloo and Beltway Poetry; and she was the first person to use the term “Hip-Hop Theater” in print.

Her artworks include the installation Black Space at Martin Luther King Jr. Memorial Library, Washington DC, which comprises a small house placed on an outline of the city, alluding to the tiny house architectural movement and the housing problems in DC.

She wrote and performedRadon concentration measurements were performed using CR-39 detectors enclosed in small cylindrical (5-cm height, 3-cm diameter) diffusion chambers. Detectors were etched in 6.2 M NaOH at 90°C for 2 hours, washed in clean water for 10 minutes, and then air-dried. The tracks on the CR-39 were counted with an automatic setup consisting of an optical microscope connected to a charge coupled display camera controlled by a personal computer. The calibration factor for converting track density to ^222^Rn concentration was obtained in a calibration experiment performed at the Radioactivity Laboratory of the Department of Physics, University of Trieste, Italy. These procedures were conducted in accordance with US Environmental Protection Authority Quality Assurance/Quality Control documents.\[[@CIT13]\]

The measurements of ^222^Rn concentration were performed for a period of 3 months from October 2007


   Ceramic tiles   29.2          294.5               1.86
  \(C\)           Paint    Paint       Linen           8.3           288.0               1.82

Conclusions {#sec1-4}
===========

A survey of ^222^Rn measured by passive type radon monitors (CR-39) in offices in Nigeria oldest university campus was conducted over a period of 3 months. Based on 24 measurements, the arithmetic mean andin an office with combination (B) can receive an average annual effective dose that is higher (by a small amount 0.04 mSv) than one working in an office with combinations (A) and (C)

The authors greatly appreciate Professor Gianrossano Giannini and Dr Massimo Vascotto, both of the University of Trieste, Italy, for the supply of the CR-39 detectors used for radon measurements in this study. They are also grateful to the occupants of the offices surveyed in UI for their kind help and cooperation during the measurements. The first author thanks the Abdus Salam International Center for Theoretical Physics (ICTP).

**Source of Support:** Nil

**Conflict of Interest:** None declared.


Description Orient Automatic Dress Watch with White Dial, Roman Numeral Markers #ER2400BW The new Orient Bambino dress watch features an Orient made 21-jewel automatic movement, a white dial with rose goldtone applied Roman numeral markers, matching rose goldtone hands, a solid screw-in case back, date window at 3:00, a domed mineral crystal, and a dark brown leather strap. Great watch for wearing to the office or out for dinner. It is a beautiful watch with classic elegance and style. it will look VERY handsome on your wrist!

Notes from Orient:

With a domed crystal that helped define the popular Bambino series, the newest Bambino is refreshed with a new look that is worthy of the popular achieved by its predecessors. The ER2400BW sports a white dial with rose gold accents;risk, and potential economic sanctions. Therefore, most defense work is done in preparation for war: training, running drills, and maintaining military supplies, all to increase readiness for the next battle.

Hacking and stealing your enemy’s military secrets is just another element in this warm up for a war that has yet to begin.

But psychological warfare can also be used to directly impact another nation’s strength in times of peace. Effective psy-war will affect an enemy’s domestic situation, while subverting its political power – a light impact could affect the elections, but a heavy impact could cause a revolution. This thereby weakens the threat posed by the enemy.

All methods of warfare other than military might can fall under the classification ‘political warfare’ (pol-war). Psychological warfare is an indispensable weapon in


CCP itself, the government, and the military, including the Central Publicity Department, the United Front Work Department, and the Communist Youth League, but also reach as far as the Taiwan Affairs Office and its peripheral organizations.

The attacks on public opinion online that everyone is familiar with are meticulously planned and then implemented by these departments.

As for the CCP’s psy-war department, they are more focused on the tactical side of psychological warfare – propaganda broadcasts, a war of words – and do not really engage directly in strategic psychological warfare against Taiwan.

So, what are the corresponding departments for countering cross-Strait psychological warfare and public opinion attacks in Taiwan? Let’s look at the same three sectors of political parties, the government, and the military:

On the political side, some parties andwork consists mainly of responsive action, dictated by the information released by Beijing. When they advocate the Belt and Road Initiative (BRI), we adhere to the trend and also discuss the BRI. When they deployed the aircraft carrier Liaoning for patrol, we get dragged along and also discussed the Liaoning. Taiwan’s psy-war division has fundamentally lost the ability to itself come up with creative topics that arouse positive public sentiment.

This is the general reality of Taiwan's current psy-war division. It is a perfect example of the cost of having unqualified professional leadership – even though the division has the most outstanding officers within the entire army, each with exceptional individual abilities, when they are assembled into a mismatched group under the leadership of their senior commanding officers, none


could've had Jim Bob, the son of God." "Praise to him, Jim-Bob" "He, who finds the stuff And gets me a job, Jim-Bob" "Jesus was an only child." "Thank God!" "Who would want to be Jerry, the brother of Christ?" "That's a tough gig." ""Come on, Jerry, we're going to the beach."" "Jesus's gonna walk on the water, feed everybody, heal them and get a whole bunch of disciples." "I'll sat there with a rash and sand in my ass." "Great day for me!" "He ends up in a bar at the age of 30 going: "Yeah, I'm Jerry Christ." "Yeah, I healed somebody." "Come here Spot, heel!" "Look at that!"" "Jesus is a carpenter, I'm a plumber." "You do the math!" "And people say to me Jesuswasn't Jewish... of course he was Jewish!" "Thirty years old, single, living at home with his parents, come on." "Working in his father's business, his mother thought he was God's gift, he's Jewish!" "Give it up!" "It's an old tradition!" "And if he was Jewish, and many of his Disciples were Jewish, for the Last Supper, would they not have gone out for Chinese?" "'Welcome to Yahweh." "Hold on one minute; no service, no sandals." "Okay, you come in now." "You're twelve." "All I got is two tables of six." "They're not together." "I also have a table by the window, but you all have to face this way." "You are glowing, so I guess we don't need that lamp, that's very nice!" "You've just turned a Szechwan


shit." "Get to know this."" ""You, Americans." "Fuck all of you Americans!"" ""Americans, you politically correct." "You cultureless crack Americans."" ""We hate all of you." "Fuck off!"" ""The Germans are here." "Hello, Americans!"" ""I love you!" "Come on, Americans."" ""Welcome back, Americans."" ""You can build the Disneyland near Paris."" ""We won't go, but build it."" ""I will have a Minnie mouse with armpit hair." "It will be great!"" "Smoking a Galloise, going:" ""I never loved Mickey"." ""He has three fingers." "What am I, a bowling ball?" "Fuck off!"" ""Don't love him!"" "But there is one country that watches out for all of us:" "the Swiss, ya!" "The Geneva Convention." "If there's ever a nuclear war, they will be the only people going:" ""Vhat was that noise?"" "In their"Before people were saying "I go to boxing to watch the sport of boxing."" "like saying, "I go to stock car races to see people take left turns all day."" "No, you go to boxing to see somebody get the fuck beat up." "Even the guy who loses is going:" ""I have 18 million dollars."" ""I don't know where the fucking is." "I'm gonna buy me a big ass house, but I can't find it." "Fuck off!"" "Boxing was the same." "And then:" "Mike Tyson!" "Mike Tyson comes along and bites somebody." "Let's get ready to nibble!" ""Oh, dear God, he bit somebody!"" "I'm saying "You're lucky he just bit somebody." "Mike just got out of prison." "You're lucky he didn't fuck him."" "You bite somebody in jail:"


have fuck her with a Koala's dick!" "Fuck off!" "I would rather lick my own balls, than fuck that Panda bitch!" "There's only one animal who can tell you if she's happy and wants to mate." "That is Coco, the silver back Gorilla." "She saw me, the blue eyed simian." "She was intrigued." "She said to her trainer..." " What is that mean?" " She wants you to tickle her." "OK, I tickle her..." "Then she goes..." " What is that mean?" " She wants you to lift your shirt." "I lift my shirt, she reaches out and grabs both my nipples." "And when an 800 pound Gorilla's got you by the titts... you listen!" "Then my balls went:" ""Somebody wants to play."" " Should we go toNegative Equity Flows Reflective Of A Cautious Investor

April 11 2019 David Templeton

A little less than a month ago I wrote a post noting weekly flows into equity mutual funds and ETF's had turned decidedly positive, and in fact were the largest inflows looking back an entire year. I rhetorically pondered if the increase in equity flows was a sign equity markets were topping, especially after such a strong start to the year. From a contrarian perspective, had investors jumped into equities near a market top, even if just an intermediate one? On the contrary, as the below chart panel shows, domestic equity flows have once again turned negative over the course of the last two weeks. If world equity flows are included, equity flows are negative for the


last three weeks according to ICI data. Fixed inflows have been positive for thirteen consecutive weeks.

From a return standpoint equities have far outpaced fixed income or bond returns as seen in the following two charts. Notable in the equity return chart is the top performing equity index is small cap followed by the Equal Weighted S&P 500 Index. In other words, the equity market returns are more broad based and this is a positive market sign. The weakest returning index is the one consisting of the fifty largest S&P 500 market capitalization weighted stocks. Fixed returns are low single digits and this is the area of the market attracting investor dollars.

As it relates to sentiment and from a contrarian perspective, market peaks, even if only short term, tendto play at par. There’s also Griffin Reinhart, who played well enough early with Eric Gryba to stay in the lineup until injuries hit.

Andrej Sekera—Brandon Davidson

Darnell Nurse—Oscar Klefbom

Griffin Reinhart—Eric Gryba

Could we see HS’s for Mark Fayne and Andrew Ference? It may happen. One thing I believe the box above shows? Giving Justin Schultz a tough zone start probably isn’t the right choice. I believe Dallas Eakins got it right.

DANGER FENWICK RATE PER 60

I lifted this from the brilliant blog Oilers Nerd Alert, please click on the link because I didn’t ask permission to do it. I think young G is on to something here, this DFA/60 number (Dangerous Fenwick) from the Habs game is very insightful and offers some reasoning re: Fayne’s handling. I have been (and am)


talent. In game 11 of his NHL career he beat one of the best defensemen in the game, on a play that might have resulted in a penalty. How a man could be both unavoidable to the viewer and stealth to the opposition is the stuff of legends. We’re running out of words.

Nail Yakupov’s boxcars are splendid and his level of awareness—especially in the offensive end—is reaching new levels. There’s a tendency to credit others for his development, but Nail is his own man and we rarely take into account that lost half-season. Hard to believe this is the same player, although he reminds us from time to time with an errant pass or a burst to nowhere in order leave his man open in the defensive zone.lastyear with Oil.

There has to be no team in history that makes it more difficult for themselves than the Oilers. You watch any other game in the NHL, seriously any other game, and I don’t know how you can’t be left baffled as to how other teams have it so easy to do the simple things. Breaking out with the puck, setting up on the PP, etc.
I say it every game, why is it so hard for even McD to get a pass? He has to almost create an ungodly take-away just to get the puck.

The other person that deserves a swift kick in the ass tonight is Pouliot. Since he has been here there have been three (counting tonight) games where he has taken an offensive zone


the automatic dishwasher has also revolutionized what can be used to clean dishes. Harsh or abrasive chemicals which previously were known for cleaning power and sterilizing effect, but which could be hazardous or unpleasant to individuals in contact with them can be used in a dishwasher. Further, the ability of dishwashers to control water pressures, temperature, time, and spray angles can produce dishes which are truly cleaner and safer than those washed by hand.
While there can be no doubt the dishwasher is a valuable labor saving device, there are still a couple of places where it creates some additional labor over hand washing. In the first instance, the dishwasher requires hand loading. Traditionally, loading of a dishwasher is accomplished through the use of one or more “racks” whichfashion conveyor fashion, they do not resolve the issue of storage as the dishes. Dishes, after washing are simply deposited out of the dishwasher to await being unloaded. As conveyor dishwashers generally do not use doors, this type of arrangement is totally unsuitable for a residential application and the dishes at the end of the conveyor are not intended to be stored as they are not actually removed from the washing chamber of the dishwasher.
Instead, in a conveyor dishwasher, the dishes still have to be removed and separately stored in order to utilize the dishwasher to wash more dishes and to prevent dishes which have completed the cycle from getting wet from later wash cycles. Further, these type of conveyor systems rely on separation of a single compartment


published today. Four in ten Europeans plan to spend their main holiday in their own country (majority of people in Greece, Croatia, Italy and Bulgaria). Three in ten people expect their main holiday to be in the EU, and over four in ten intend to have at least one of their trips in the EU in 2014. A quarter plans travelling to a non-EU country (24%) but only 16% will have their main holiday outside the EU.

According to the survey, the tourism sector has been an engine of domestic demand-driven economic growth in 2013 as well, with more people choosing to spend holidays outside of their own country but within the EU. In 2013, 38% of Europeans spent their main holiday in another EU country, which is 55*(sqrt(75)*1 + sqrt(75) + sqrt(75))))*1 + -3))**2.
6240*sqrt(3) + 43876
Simplify 1 + sqrt(432) + (4 + sqrt(432)*4 - sqrt(432)) - ((sqrt(363)*-1 + 2 - sqrt(363)) + -3)**2.
-1448 + 4*sqrt(3)
Simplify (-3 + ((2 + sqrt(475) + 5 - sqrt(475)*2*-6) + 2 + -3)**2)*-5.
-401540 - 3900*sqrt(19)
Simplify -1*((3*((-3*sqrt(119) + sqrt(119))*4 + sqrt(119)))/(sqrt(77)/(sqrt(11) - (sqrt(11) + sqrt(99))) + sqrt(315)/sqrt(5)) + 4).
-4 + 63*sqrt(17)/8
Simplify (5*sqrt(896) - sqrt(224)*-4)/(6*5*sqrt(1152)).
7*sqrt(7)/90
Simplify (1 + (1*(sqrt(432) + sqrt(432) + -6*(sqrt(432) + 1)) + (4*(-2*sqrt(432) - sqrt(432)) - (sqrt(432) + (sqrt(432)*-1*4 - sqrt(432)) + sqrt(432))))*1)**2.
1560*sqrt(3) + 73033
Simplify ((-1 + sqrt(275) + -2 + sqrt(275) - sqrt(275))**2 - sqrt(275)) + (sqrt(275)*2)**2 + 0 - (-4 + (sqrt(275) - (sqrt(275) + 0)*1) + 3).
-35*sqrt(11) + 1385
Simplify -1 + (-4*1*(sqrt(637) + 4*(sqrt(637) - (sqrt(637) + -1 + sqrt(637))) + 2)*5*-6)**2.
-3628800*sqrt(13) + 83073599
Simplify ((sqrt(33) +


Pets on Property

Spring Creek Ranch is located on a 1,000 acre wildlife refuge providing sanctuary for Moose, Elk, and Mule Deer. Because of this distinction we are unable to allow pets to stay at Spring Creek Ranch. If you would like to bring your family pet with you on vacation to Jackson Hole, there are some very excellent boarding facilities located near the Ranch. Our reservation specialists can give you more information when making your reservations.you, Weiss… Thank you for everything. "

"Heh, seriously, I’ve done nothing, your father and uncle were the ones who helped you the most"

"Maybe, but thank you. "

"You… You’re welcome Yang"

"So… Are we really going to camp here? Like… Couldn’t we go to the hotel or anything? "

Coco was groaning as she looked at her team setting up three tents as well as every other camping material they had, at the edge of the clearing around the house. After three weeks of sleeping in the sand she was at least hoping to lay in the comfiest, fluffiest, softest bed in Vale, but NO, she had to sleep in a god damn sleeping bag for who knows how long. At least it was comfortable to snuggle with her girlfriend.

"Or… Oh,


angry and was about to tell to Yang how she felt about that treason, but she was prevented of doing such by a giggling Velvet.

“So, who’s that friend that we’ll like Yang? Did you forget to say anything to us ab…” the bunny girl never finished her sentence, shock overcoming every brain power she had, as it did to everybody else.

In front of her stood a blushing seven-year-old girl with a small red helmet with a rose decal on the side. Wearing a pink t-shirt with black shorts, the small girl had long purple hairs with white highlights that flowed up to the middle of her back, the bangs of her hair making her bright blue eyes almost flash on her pale face. She was standing at aroundAll data are available from Harvard\'s Dataverse database: <http://dx.doi.org/10.7910/DVN/IYA8Y6>.

Introduction {#sec001}
============

Microsomal prostaglandin E synthase-1 (mPGES-1) belongs to the membrane-associated proteins involved in eicosanoid and glutathione metabolism (MAPEG) super family \[[@pone.0134472.ref001]\]. It is the terminal enzyme in the metabolism of arachidonic acid (AA) via the cyclooxygenase (COX) pathway (particularly COX-2), responsible for the conversion of prostaglandin H~2~ (PGH~2~) to a more stable product prostaglandin E~2~ (PGE~2~). As PGE~2~ is a key mediator of pain and inflammation \[[@pone.0134472.ref002]\], the enhanced mPGES-1 expression is associated with many pathological conditions in humans; including myositis \[[@pone.0134472.ref003]\], rheumatoid arthritis \[[@pone.0134472.ref004]\], osteoarthritis \[[@pone.0134472.ref005]\], inflammatory bowel disease \[[@pone.0134472.ref006]\], cancer \[[@pone.0134472.ref007], [@pone.0134472.ref008]\], atherosclerosis \[[@pone.0134472.ref009]\], and Alzheimer's disease \[[@pone.0134472.ref010]\]. So, efforts are being made by several pharma companies for the development of anti-inflammatory drugs, targeting mPGES-1.

Recently Zhan *et al*.,


of molecular descriptors LogP, topological polar surface area (TPSA) and volume of the inhibitor (Vol) \[[@pone.0134472.ref044], [@pone.0134472.ref045]\]. It is important to note that protein-ligand binding always takes place in aqueous environment. During the binding of ligand to the protein a series of events will take place, i.e. desolvation of ligand and protein, conformational changes, and formation of intermolecular interactions \[[@pone.0134472.ref046], [@pone.0134472.ref047]\].

Hence, in the present study, some molecular descriptors were also incorporated with the docking scores for the accurate prediction of binding affinities of ligands towards mPGES-1. The molecular descriptors considered in the studies were LogP, TPSA, Vol and number of rotatable bonds (Nrotb). The reason for including these molecular descriptors in the study was to introduce the concept of desolvation energy penalty and conformational free energy changes occurring                  .75[\*\*](#t003fn001){ref-type="table-fn"}   .84[\*\*](#t003fn001){ref-type="table-fn"}   .81[\*\*](#t003fn001){ref-type="table-fn"}   .89[\*\*](#t003fn001){ref-type="table-fn"}   .79[\*\*](#t003fn001){ref-type="table-fn"}
  Spearman Correlation   1.00                  .67[\*\*](#t003fn001){ref-type="table-fn"}   .69[\*\*](#t003fn001){ref-type="table-fn"}   .81[\*\*](#t003fn001){ref-type="table-fn"}   .88[\*\*](#t003fn001){ref-type="table-fn"}   .71[\*\*](#t003fn001){ref-type="table-fn"}

\*\* denotes that the correlation is significant at 99% confidence level

The predictions of the training set compounds were further analysed. The 27 compounds taken for training set were classified into 8 active (IC~50~ ≤ 100nM), 10 moderately active (100nM ≥ IC~50~ ≤ 10 μM) and 9 inactive molecules (IC~50~ ≥ 10 μM). These compounds were then taken as reference


leading to enhancement in number of hits. Even in the present study it was observed that the correlation of docking programs show improvement in consensus as well as rescoring methods. In a number of studies researchers have included some molecular descriptors along with the docking scores to predict the binding affinities accurately. Li *et al*. \[[@pone.0134472.ref054]\] have developed a new scoring function called ID-Score to assess protein-ligand binding affinities. Their scoring function is based on a comprehensive set of molecular descriptors playing crucial role in protein-ligand interactions. The present study supports previous reports and also hint that molecular descriptors like LogP and Nrotb can be applied as terms for ΔG~sol~ and ΔG~conf~ and may increase the correlation of the docking programs against mPGES-1 inhibitor activity prediction. The results4,147,613, 4,151,119 and U.S. Pat. No. 4,182,693) disclose a hydrocarbon conversion process utilizing catalyst comprising major amounts of silica and minor amounts of zirconia and alumina, bulk alumina and aluminosilicate zeolites. (3-16 wt percent zeolite, 50-85 wt percent inorganic oxide gel, mostly consisting of silica and a minor amount of zirconia and alumina, and 15 to 40 wt percent of a porous absorbent, for instance bulk alumina.) The absorbant is in place to absorb heavy metals present in the petroleum crudes, which can deactivate the zeolite. Increased activity/selectivities for these catalysts compared to a more conventional Y zeolite containing kaolin and a silica-alumina hydrogel is claimed. Lim et al. (U.S. Pat. No. 4,206,085) report an improved abrasion resistant zeolite, prepared from a faujasite type zeolite, hydrated alumina and


ammonium polysilicate or silica sol and clay to form microspheres. The use of ball clay is present because the clay has pre-cracking activity which is important in the hydrocarbon chemistry.
Lim et al. (U.S. Pat. No. 4,325,845) describe a method for producing zeolite cracking catalysts using sodium silicate, derived from silica gel, in combination with clay to form catalysts of good attrition resistance. The authors eliminate the alumina from the formulation (pseudoboehmite), claiming it is a source of coking, or deactivation of the catalyst and sodium silicate is substituted for the alumina hydrate. The silicate is added to the ball clay and zeolite to form the final catalyst in order to enhance catalytic activity.
Scherzer (U.S. Pat. No. 4,987,110) claims an attrition resistant cracking catalyst using a molecular sieve (zeolite)the GNWT offered the DFN and its 3,600 population a total of 37,500 square-km of land with generalized interest of around 18 per cent in subsurface rights for the whole region, or 33,488 square-km with 100 per cent of subsurface rights. This is comparable to the Tlicho Agreement of 2001 which established a land base of 39,000 square-km for 3,200 citizens.

The DFN argued that going by calculations which allotted the Tlicho their land, the area of DFN lands should total around 50,000 square-km.

In January, Premier Bob McLeod suspended negotiations over the land quantum debates, stating the GNWT’s land offer “represents the full extent of GNWT flexibility. If this offer is unacceptable to the Dehcho, then I suggest that we acknowledge that negotiations have failed to resolve our differences.”


/*
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 *
 * Licensed under the Apache License, Version 2.0 (the "License");
 * you may not use this file except in compliance with the License.
 * You may obtain a copy of the License at
 *
 * http://www.apache.org/licenses/LICENSE-2.0
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 * Unless required by applicable law or agreed to in writing, software
 * distributed under the License is distributed on an "AS IS" BASIS,
 * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 * See the License for the specific language governing permissions and
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/*
 * Copyright 2011-2014, by Vladimir Kostyukov and Contributors.
 *
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 * Licensed under the Apache License, Versionbest lists of top critics around the country, as well as into the hearts of a very sizable audience. Perhaps there wasn’t enough room for two Asian movies?”

The Motion Picture Academy of Arts and Sciences has doubled the number of women and people of color in its membership since launching the A2020 initiative in 2016. Sixteen percent of its nearly 9,000 members are people of color.

“[The change] that many of us want to see must come from the industry at large — the financiers and decision-makers, agents and managers, publicists and critics — well before Oscar time rolls around,” Yang said.

The #GoldOpen lineup in 2020 includes “Birds of Prey,” “Mulan” and “No Time to Die.”


by the fact that if he lost a round, he had to pay off the other players, and that could be devastating to his bankroll. But if he won, the other players _had to pay him_. Blackjack was the game with the greatest risk but also the greatest reward.

One night, Jack had lain on his cot, thinking. He'd seen a lot of cheating among the Mexicans. They marked cards with shoe polish or palmed out a pair before a hand began. It occurred to him that if he was going to cheat, wouldn't blackjack be the game to do it in?

He thought about it for months. The Mexicans were suspicious guys, and manipulating the cards was out of the question. But instead of manipulating the cards, why notNevada if you really want to save 1%.

~~~
ideas101
thanks ... i used cayman island just as an example but there are many others -
i think it won't be that profitable else all YC companies would have been
taking advantage of this. Do you know where all YC companies are
incorporated????

~~~
rms
All are Delaware C Corps

~~~
kingnothing
If you're a Delaware corp, but you live and operate in, say, California, don't
you also have to be incorporated to do business in California and pay taxes on
whatever income is received there?

Or is the whole point that we're doing business "on the internet" so that
doesn't apply?

~~~
xirium
SGI was originally incorporated as a California corporation in November 1981,
and reincorporated as a Delaware corporation in January 1990. --
<http://en.wikipedia.org/wiki/Silicon_Graphics>

I presume that you pay lawyers in Delaware to use their office address as


So if you need your foreign revenue to pay the domestic bills you're
going to get hit. Also I believe that a couple of years ago Congress made it
more difficult to do this sort of thing after it started impacting tax
receipts.

------
pg
Empirically the answer seems to be no.

------
daniel-cussen
I've thought about this...there are a lot of countries that will charge you
little or no taxes, and some countries that will let you hire anyone you want
(I find freedom in hiring more important than reducing tax exposure), but I
don't know how many countries have both these things. Also, tax haven
countries are sometimes very expensive places. Dubai, Montecarlo, Bermuda, and
so forth. All insane. Even if you're not headquartered there, you might have
the expense hit you in some form or another. The expense might bemore
damaging than paying taxes in US.

There's probably a reason only a few industries see their companies
incorporate in tax havens (mostly insurers and financiers). The government
might insist on having you fill out many phone-books worth of forms, pay
special taxes, abide by certain restrictions, and so on. It might be outright
illegal. A lot of companies got established in Delaware because this presents
advantages; if they're not incorporating in a tax haven, I doubt it's because
they're lazy.

On the other hand, one strategy I haven't heard being used, but have found
nothing wrong with (so far) is going IPO with Nasdaq Portal. It costs like
$8000 and makes stock available to investors with 100M or more in liquid
assets, termed Qualified Institutional Investors. I haven't heard of anyone
doing it, and I might be glossing over a


propose homologies to all four mammalian pallial areas and conclude that the posterior zone of the dorsal telencephalic area in teleosts is homologous to the piriform cortex and is formed by a migratory stream of cells originating in a dorsomedial zone of the pallium (the primordial medial zone of area dorsalis telencephali). In this review we critically discuss and justify these findings in the context of forebrain evolution in fishes.implemented as separate processes communicating with DBUS and exchanging video frames using fd passing.

Some features of Pinos

Easier switching of cameras in your applications

It will also allow you to more easily allow applications to switch between multiple cameras or mix the content from multiple sources. Multiple types of video inputs

Supports more than cameras. Pinos also supports other type of video sources, for instance it can support your desktop as a video source. GStreamer integration

Pinos is built using GStreamer and also have GStreamer elements supporting it to make integrating it into GStreamer applications simple and straightforward. Pinos got some audio support Well it tries to solve some of the same issues for video that PulseAudio solves for audio. Namely letting you have multiple applications sharing the same camera hardware. Pinos


recited his name and birthdate before entering into a private phone discussion on the courtroom telephone with Zeyad Halbouni, a paralegal who works with Boyede’s defence lawyer, Keli Mersereau.

His next court appearance by video on the second-degree murder charge, along with a charge of offering an indignity to a dead body, was set for Nov. 10.

An Ontario Court preliminary hearing on his other charges has already been set for March 5. He will make a separate video court appearance on those charges on Nov. 24.

While Halbouni and assistant Crown attorney Roger Dietrich sorted out the upcoming court date with the justice of the peace, Boyede, dressed in the standard jail-issued orange jumpsuit, said nothing.

At one point, he yawned.

The court documents detailing Boyede’s other charges offer some glimpse intohomology
---------------------------------------

A significant thread in recent research in symplectic and contact topology has concerned the study of smooth manifolds through the symplectic structures on their cotangent bundles. In this setting, one can also study a pair of manifolds, one embedded in the other—in particular, a knot in a $3$-manifold—via the conormal construction. If $K \subset \R^3$ is a knot, then its unit conormal bundle, the conormal torus $\Lambda_K$, is a Legendrian submanifold of the contact cosphere bundle $ST^*\R^3$. Isotopic knots produce conormal tori that are isotopic as Legendrian submanifolds, i.e., the Legendrian isotopy type of the conormal torus is a knot invariant. The fact that this invariant is nontrivial depends essentially on the contact geometry: the conormal tori of any two knots are smoothly isotopic, even if the knots


group ring of $H_2(V,\Lambda)$ rather than $H_1(\Lambda)$, the difference being whether one associates to a holomorphic disk its relative homology class in $H_2(V,\Lambda)$ or the homology class of its boundary in $H_1(\Lambda)$. In the case of knot contact homology, our setup amounts to specializing to $U=1$ in the language of [@EENStransverse; @Ngtransverse; @Ngsurvey] or $Q=1$ in the language of [@AENV]. Also, as mentioned in the introduction, the version of the DGA that we consider here is the fully noncommutative DGA, in which homology classes in $H_1(\Lambda)$ do not commute with Reeb chords. To get loops rather than paths we fix a base point in each component of $\Lambda$ and capping paths connecting the base point to each Reeb chord endpoint, see Figure \[fig:disks\].

If $\Lambda \subset V$ is a\alpha_5 a_7 \alpha_6 a_8 \alpha_7$, respectively. Here $a_5,a_6 \in \mathcal{R}^{11}$, $a_4,a_8 \in \mathcal{R}^{21}$, $a_7 \in \mathcal{R}^{12}$, $\alpha_1,\alpha_6 \in H_1(\Lambda_1)$, and $\alpha_0,\alpha_2,\alpha_3,\alpha_4,\alpha_5,\alpha_7 \in H_1(\Lambda_2)$. The boundaries of the disks lie on $\R\times \Lambda_1$ and $\R\times \Lambda_2$ as shown, and represent the homology classes indicated after closing up with suitably oriented capping paths, see Remark \[r:coeffs\]. Small arrows denote orientations on Reeb chords. []{data-label="fig:disks"}](disks "fig:"){width="80.00000%"}

The differential $\partial$ on $\A_{\Lambda_1 \cup \Lambda_2}$ is defined to be $0$ on $e_i$ and on elements of $\Z[H_1(\Lambda_i)]$ and is given by a holomorphic-disk count for Reeb chords of $\Lambda_1
\cup \Lambda_2$. For a Reeb chord $a\in\mathcal{R}^{ij}$ the disks counted in $\partial a$ are maps into $\R\times V$ and have boundary on $(\R\times\Lambda_1)\cup(\R\times\Lambda_2)$, one positive puncture where it is asymptotic to $\R\times a$ and several negative


$\Z$). In general, in Definition \[def:KCH-triple\] we would want to set $R_{Kp} = H_d(\A_{\Lambda_K,\Lambda_p})$ and $R_{pK} =
H_{1-d}(\A_{\Lambda_p,\Lambda_K})$, where $d\in\Z$ corresponds to the choice of homotopy class of path. (In all cases we still have $R_{KK}
= H_0(\A_{\Lambda_K,\Lambda_K})$.)

This indeterminacy would seem to pose problems for Proposition \[prop:KCH-triple\]. However, we can eliminate the ambiguity by stipulating that we have picked the unique choice of grading for which $$\min \{d \,|\, H_d(\A_{\Lambda_K,\Lambda_p}) \neq 0\} = 0.$$ This is because with our preferred choice of grading, $H_d(\A_{\Lambda_K,\Lambda_p}) = 0$ for $d < 0$, while we will show that $R_{Kp} = H_0(\A_{\Lambda_K,\Lambda_p})$ is nonzero (see for instance Proposition \[prop:triple-isom\]).

If we choose $p$ sufficiently far away from $K$, then by action considerations (the action of the Reeb chord at the positive puncture of a holomorphic disk is greaterat 36 129 $-$ at 56 84 $-$ at 90 73 $-$ at 118 84 $a_1$ at 368 253 $a_2$ at 495 253 $b_1$ at 323 4 $b_2$ at 433 4 $b_3$ at 541 4 $\beta_0$ at 304 117 $\beta_1$ at 378 58 $\beta_2$ at 486 58 $\beta_3$ at 555 148 ${\color{green} \Lambda_p}$ at 430 147 ${\color{blue} \Lambda_K}$ at 348 168 ${\color{blue} \Lambda_K}$ at 339 58 ${\color{blue} \Lambda_K}$ at 447 58 ${\color{blue} \Lambda_K}$ at 514 187 ![ A disk in the moduli space $\M(a_1,a_2;\beta_0b_1\beta_1b_2\beta_2b_3\beta_3)$. Here the $\beta_i$ coefficients record the homology classes of the depicted arcs in $\Lambda_K$. The arrows on Reeb chords denote their positive orientations. []{data-label="fig:product"}](product "fig:"){width="70.00000%"}

We now describe this construction in more detail. Let $a_1$ be a Reeb chord to $\Lambda_{K}$ from $\Lambda_{p}$ and $a_2$


disk and where “$\approx$” means “is related to via a linear gluing exact sequence”, see [@EESori]. For the product, we have disks with two positive punctures and there is no natural way to order the punctures in general. However, in our case the two positive punctures are distinguished since both are mixed and have different endpoint configurations. We choose the following ordering: $$C_{a_1}^{+}\oplus L\oplus C^{-}_{b_1}\oplus\cdots\oplus C^{-}_{b_m}\oplus C_{a_2}^{+} \approx F.$$ As usual this then induces a linear gluing sequence which in the transverse case orients the moduli space.

With these orientations determined, we can now define $\mu$. Suppose that we have $\mathbf{c}_1 a_1\in \A_{\Lambda_K,\Lambda_p}^{(1)}$ and $a_2\mathbf{c}_{2}\in \A_{\Lambda_p,\Lambda_K}^{(1)}$, where $a_1$, $a_2$ are mixed chords to $\Lambda_K$ from $\Lambda_p$ (respectively to $\Lambda_p$ from $\Lambda_K$), and $\mathbf{c}_1$, $\mathbf{c}_2$ are words in pure Reebarc in $Q$ or in $L_K$ shrinks to a point in $K$, or equivalently a disk with one boundary arc that hits $K$ in an interior point;

-   $1$-level disks in which a boundary arc in $Q$ or in $L_p$ shrinks to a point at $p$, or equivalently a disk with one boundary arc that hits $p$ in an interior point.

Configurations of type $(i)$ are counted by $\Phi(\partial a)$, configurations of type $(ii)$ by $(\delta_{Q}^{K}+\delta_N^{K})\Phi(a)$, and configurations of type $(iii)$ by $(\delta_{Q}^{p}+\delta_N^{p})\Phi(a)$. The chain map equation follows.

We will be especially interested in the subcomplexes $\tilde{C}_*^{KK}$, $\tilde{C}_*^{Kp}$, $\tilde{C}_*^{pK}$ in the lowest degree. These are given as follows, where the differential is $d = \partial +
\delta_Q^K + \delta_N^K$ (the operations $\delta_Q^p$, $\delta_{L_p}^p$ do not appear for degree reasons): $$\begin{aligned}
\tilde{C}_1^{KK}


K)]$, which is crucial to recovering the knot group itself, via the natural concatenation product on $\tilde{C}_*^{pp}$, but this sends $\tilde{C}_1^{pp} \otimes \tilde{C}_1^{pp}$ to $\tilde{C}_2^{pp}$ rather than to $\tilde{C}_1^{pp}$.

Instead, we need a product on $\tilde{C}_*$ that (in our grading convention) reduces degree by $1$. Intuitively this is given by concatenating a broken string ending at $p$ and a broken string beginning at $p$, and deleting the two switches at $p$. More precisely, we use the Pontryagin product; we discuss this product and its holomorphic-curve counterpart next.

String topology and the product {#ssec:string-product}
-------------------------------

Having established isomorphisms $\Phi$ in low degree between enhanced knot contact homology and string homology, we now examine the behavior of the product map $\mu$ under this isomorphism. Recall from Section \[ssec:product\] that $\mu$ is a map $$\mu :\thinspace
\A_{\Lambda_K,\Lambda_p}^{(1)}skein relations, where the cord is drawn in red, $K$ in black, and $K'$ in gray:

1.  \[it:cord1\] $\raisebox{-3ex}{\includegraphics[height=7ex]{skein1}} = 1-m$

2.  \[it:cord0\] $\raisebox{-3ex}{\includegraphics[height=7ex]{skein3iwrapped}} = m
    \cdot \raisebox{-3ex}{\includegraphics[height=7ex]{skein3i}}$ and $\raisebox{-3ex}{\includegraphics[height=7ex]{skein3cwrapped}}
    =\raisebox{-3ex}{\includegraphics[height=7ex]{skein3c}} \cdot m$

3.  \[it:cord2\] $\raisebox{-3ex}{\includegraphics[height=7ex]{skein2a}} = l
    \cdot \raisebox{-3ex}{\includegraphics[height=7ex]{skein2b}}$ and $\raisebox{-3ex}{\includegraphics[height=7ex]{skein2c}} =
    \raisebox{-3ex}{\includegraphics[height=7ex]{skein2d}} \cdot
    l$

4.  \[it:cord3\] $\raisebox{-3ex}{\includegraphics[height=7ex]{skein3a}}
    - \raisebox{-3ex}{\includegraphics[height=7ex]{skein3b}}
    = \raisebox{-3ex}{\includegraphics[height=7ex]{skein3c}} \cdot
    \raisebox{-3ex}{\includegraphics[height=7ex]{skein3d}}$.

Note that a typical element of $\Cord_{KK}$ is a linear combination of products of cords and elements of $\Z[l^{\pm 1},m^{\pm 1}]$, and multiplication in $\Cord_{KK}$ is given by formal concatenation of products.

We can extend Definition \[def:cordalg\] to cover cords with endpoints at $p$ as well, where the relations only apply near


$K$.

Linearizing with respect to this augmentation gives the linearized contact homology $$\LCH^\epsilon_*(\Lambda_K \cup \Lambda_p) =
(\LCH^\epsilon_*)_{\Lambda_K,\Lambda_K} \oplus
(\LCH^\epsilon_*)_{\Lambda_K,\Lambda_p} \oplus
(\LCH^\epsilon_*)_{\Lambda_p,\Lambda_K} \oplus
(\LCH^\epsilon_*)_{\Lambda_p,\Lambda_p}.$$

As discussed previously, in [@Ngframed] it is shown that $(\LCH^\epsilon_1)_{\Lambda_K,\Lambda_K}$ recovers the Alexander module $H_1(\tilde{X}_K)$. Here instead we have the following.

We have isomorphisms of $\Z[m^{\pm 1}]$-modules $$(\LCH^\epsilon_0)_{\Lambda_K,\Lambda_p} \cong
(\LCH^\epsilon_1)_{\Lambda_p,\Lambda_K} \cong H_1(\tilde{X}_K) \oplus
\Z[m^{\pm 1}].$$

We will prove the isomorphism for $(\LCH^\epsilon_1)_{\Lambda_p,\Lambda_K}$; the isomorphism for $(\LCH^\epsilon_0)_{\Lambda_K,\Lambda_p}$ follows by symmetry between $\Cord'_{Kp}$ and $\Cord'_{pK}$. The complex whose homology computes $(\LCH^\epsilon_*)_{\Lambda_p,\Lambda_K}$ is the free $\Z[m^{\pm 1}]$-module generated by Reeb chords to $\Lambda_p$ from $\Lambda_K$, with the differential $\d^{\text{lin}}$ given by applying the augmentation $\epsilon$ to all pure Reeb chords from $\Lambda_K$ to itself to the usual differential $\d$. In particular, since the degree $1$ homology $(\LCH^\epsilon_1)_{\Lambda_p,\Lambda_K}$ is the quotient of the $\Z[m^{\pm 1}]$-module generated by degree $1$the free $\Z[m^{\pm 1}]$-module generated by unframed $pK$ cords by the skein relations and from Definition \[def:unframedcordalg\], where $l$ is sent to $1$ and all $KK$ cords are sent to $1-m$. Relation then says that $pK$ cords are unchanged if we move their $K$ endpoint over $\ast$, while relation becomes: $$\raisebox{-3ex}{\includegraphics[height=7ex]{skein31a}}
- m \raisebox{-3ex}{\includegraphics[height=7ex]{skein31b}}
= (1-m)\raisebox{-3ex}{\includegraphics[height=7ex]{skein31c}}.$$ That is, if $\gamma_1,\gamma_2,\gamma_3$ are unframed $pK$ cords that are related as shown in the left side of Figure \[fig:quandle\], then we impose the relation: $$\gamma_1 - m \gamma_2 = (1-m) \gamma_3.$$

Thus we can describe $\Cord'_{pK} \otimes_\epsilon \Z[m^{\pm 1}]$ in terms of a knot diagram for $K$ as follows. Use the diagram to place $K$ in a neighborhood of the $xy$ plane in $\R^3$, and place $p$ high above the $xy$ plane along the $z$ axis.


R_{pK} \stackrel{\cong}{\to} R(1-m)$ and $R_{Kp} \stackrel{\cong}{\to} R$ induce a ring isomorphism \[prop:twosided\] $$\phi :\thinspace R_{pp} \stackrel{\cong}{\to} R(1-m)R$$ where $R(1-m)R$ denotes the two-sided ideal of $R$ generated by $1-m$.

Same as the proof of Proposition \[prop:triple-isom\], but now use the fact that $\phi$ is defined on $R_{pp}$ by $$[x_1]\{\alpha_1\}[x_2]\cdots \{\alpha_{k-1}\}[x_k]
\mapsto x_1\alpha_1(1-m)x_2 \cdots \alpha_{k-1}(1-m)x_k$$ and that any element of $R_{pp}$ can be written as $[x]$ for some $x\in R$.

Although $R(1-m)R$ is not all of $R$, we observe the following.

The submodules $\Z = \Z \cdot 1$ and $R(1-m)R$ of $R$ are complementary: \[prop:complementary\] $R \cong
\Z \oplus R(1-m)R$ as $\Z$-modules.

The homomorphism from $\pi$ to the trivial group induces a map $R =
\Z[\pi] \to \Z$, which restricts to the identity on $\Z$ and to the zero map on $R(1-m)R$; thus $\Z \cap R(1-m)R = 0$.226 $c_{0 \xi}$ at 180 160 ${\color{green} L_\xi}$ at 127 230 ${\color{green} \Lambda_\xi}$ at 86 236 ${\color{blue} \R^2}$ at 378 184 ${\color{red} L_0}$ at 259 143 ${\color{red} \Lambda_0}$ at 297 135 ${\color{red} D'}$ at 336 37 ${\color{red} D_\epsilon T^*D'}$ at 252 381 ${\color{magenta} \C_\eta}$ at 166 350 ![ The construction of $W_0(\epsilon)$ from $T^*\R^2$. []{data-label="fig:wrapped-R2"}](wrapped-R2 "fig:"){height="50.00000%"}

Consider $T^{\ast}\R^{2}$ as above and fix the cotangent fiber $L_0$ thought of as the conormal of the point at the origin. We will construct a Weinstein manifold $W_0(\epsilon)$ with Lagrangian skeleton $\R^{2}\cup L_0$ by attaching a punctured Lagrangian handle to the Legendrian ideal boundary $\Lambda_0$ of $L_0$. The manifold $W_0(\epsilon)$ with its Liouville vector field is then the ambient space for partially wrapped Floer cohomology adapted to $\partial L_0$ and the boundary circle


cohomology. The picture for the partially wrapped Floer cohomology of $\C$ is analogous to the calculation of the wrapped Floer cohomology of a cocore disk in Legendrian handle attachment, which via the surgery isomorphism [@BEE] is isomorphic to the Legendrian contact homology of the attaching sphere. In our setting, $\C$ plays the role of the cocore disk, while $\Lambda_K$ plays the role of the Legendrian attaching sphere. Compared to the situation in [@BEE], we are attaching a different handle, and the Reeb flow inside the handle is more complicated but easy to control from the point of view of holomorphic disks since all Reeb chords inside the punctured handle have index $0$.

Our calculation of the partially wrapped Floer cohomology of $\B$ relates it to the DGA of $\Lambda_{K}\cup{#ssec:direct}
------------------------------------------------

Here we describe a direct connection between partially wrapped Floer cohomology of $\B$ and $\C$ in $W_K$ and the topology of the loop space of the knot complement, which explains the geometry underlying the isomorphisms in Proposition \[prop:triple-isom\] and the ring isomorphism $HW^0(\B,\B) \cong \Z[\pi_1(\R^3 \setminus K)]$.

${\color{magenta} \C}$ at 239 335 ${\color{green} \B}$ at 80 226 ${\color{red} L_K}$ at 238 227 ${\color{blue} Q}$ at 143 169 ${\color{orange} M_K}$ at 152 208 $W_K$ at 162 64 ${\color{red} L_K}$ at 543 285 ${\color{blue} Q}$ at 543 241 ${\color{orange} M_K}$ at 543 102 ![ Constructing the Lagrangian $M_K$ from the Lagrangians $Q$ and $L_K$: on the left, depicting $M_K$ within $W_K$; on the right, the two possible Lagrange surgeries.[]{data-label="fig:wrapped-MK"}](wrapped-MK "fig:"){width="80.00000%"}

As a first step, following [@AENV], one can construct a Lagrangian submanifold


the partially wrapped complexes) to words of Reeb chords of $\Lambda_K \cup \Lambda_p$. The geometric maps from $CW(\C,\C)$, $CW(\C,\B)$, and $CW(\B,\C)$ to chains in loop/path spaces then descend in homology to maps from $R_{KK} = HW^0(\C,\C)$, $R_{Kp} = HW^0(\C,\B)$, and $R_{pK} = HW^0(\B,\C)$ to $\Z[\pi_1(M_K)]$. These are precisely the isomorphisms in Proposition \[prop:triple-isom\] from the KCH-triple to subrings of $\Z[\pi_1(\R^3\setminus K)] = \Z[\pi_1(M_K)]$; furthermore, the map on $CW(\B,\B)$ induces the isomorphism from $\Z\oplus R_{pp} \cong HW^0(\B,\B)$ to the entire group ring from Proposition \[prop:ring-isom\].

Indeed, the algebraic maps constructed in the proof of Proposition \[prop:triple-isom\] correspond to the maps from chains of broken strings to chains of paths on $M_K$ determined by [@AENV Theorem 6.5]. More precisely, the algebraic maps correspond to the disks for which the length functional on the image chainin a closed manifold [@AS; @Ab]. In particular, the identification of the pair-of-pants product in wrapped Floer cohomology of the fiber in a closed manifold with the Pontryagin product on chains of loops is directly analogous to our identification of the products in $HW^0(\B,\B)$ and $\Z[\pi_{1}(\R^{3}\setminus K)]$.

Relation to sheaves and cosheaves {#ssec:sheaves}
---------------------------------

This paper has presented a holomorphic-curve approach to the result that the conormal torus is a complete knot invariant. This result was previously established by the methods of microlocal sheaf theory in [@Shende]. We now explain how these two approaches are related.

Consider a closed manifold $M$. Abouzaid has shown on the one hand that the wrapped Floer cohomology of a cotangent fiber in $T^*M$ is naturally identified with chains on the based loop space of $M$ [@Ab],


Q:

maximum and minimum value?

I have made a matrix using vector and iterator, how can I find maximum and minimum value from it. It is something like:
vector<int> > matrixes(10);
typedef std::vector<std::vector<int> >::iterator it;

it rows = matrixes.begin();
 if (rows->size() == 10)
++rows;
rows->push_back(res);

}

for(size_t q=0; q < matrixes.size(); ++q)
{
    for(size_t r=0; q < matrixes[q].size(); ++r)
    cout << matrixes[q][r] << " ";
   cout << endl;
}

I want to find maximum and minimum value through it, how is it possible?

A:

Use std::max_element and std::min_element in the STL.

A:

Just add two variables to hold the maximum and minimum value.
Update the portion where you display it.
vector<int> > matrixes(10);
typedef std::vector<std::vector<int> >::iterator it;

it rows = matrixes.begin();

int maxVal,minVal;

if ( matrixes.size() > 0 && matrixes[0].size() > 0 )
 maxVal = minVal =  matrixes[0][0];

for(size_t q=0;The group, who spent one day exploring the lava flows, which cascaded down from a 200ft cliff, braved red-hot water temperature tipping 50 degrees Celsius. Ben said: "One of the biggest dangers was the toxic steam produced when the lava comes into contact with the water. "You could hear the sound of the lava hissing as it hit the ocean. It was out of this world."Picture: Alexandre Socci / Barcroft Media

Credit : Alexandre Socci / Barcroft Media


import { EventEmitter } from '@angular/core';
import { ChartPointComponent } from './ChartPointComponent';
import { ChartEvent } from './ChartEvent';
export declare class ChartSeriesComponent {
    point: ChartPointComponent;
    click: EventEmitter<ChartEvent>;
    afterAnimate: EventEmitter<ChartEvent>;
    checkboxClick: EventEmitter<ChartEvent>;
    hide: EventEmitter<ChartEvent>;
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change has started already. and i'm not sure i like it.
no one enjoys leaving treasure behind. no one.

but it seems that my destiny is now rather decided by a bunch of cute kittens rather than myself.


current density at −100 mV in the presence of the TLR‐4 blocking antibody increased from −12.7 ± 5.1 pA/pF to −20.0 ± 7.5 pA/pF (*n* = 9) (Fig. [4](#jcmm13033-fig-0004){ref-type="fig"}D). These results indicate that oxLDL‐induced inhibition of inward currents of potassium is TLR‐4‐dependent.

![oxLDL‐induced inward rectifier K^+^ channel closure is TLR‐4‐dependent. Current density (pA/pF) in RAW264.7 cells was documented when cells were exposed to foetal bovine serum (FBS, as control) or oxLDL (30 mg/ml) in the presence of 10% FBS, or in some cases pre‐treated with the blocking antibodies of TLR‐4 (8 μg/ml) (**A**), CD36 (8 μg/ml) (**B**) or LOX‐1 (8 μg/ml) (**C**). Histogram showing current density of cells specifically evoked at −100 mV when the cells were pre‐treated with these antibodies (**D**) (mean ± SD from 5 to 10and we did not detect any outward K^+^ current in RAW264.7 cells, although glyburide, which is an outward K^+^ channel inhibitor, also attenuated oxLDL‐induced MCP‐1 release. It has been reported that calcium stress may activate ERK MAPK [38](#jcmm13033-bib-0038){ref-type="ref"}, and our data further show that ERK MAPK regulates closing and opening of Ca^2+^ and K~ir~ channels and thus regulates MCP‐1 release. Inhibition of oxLDL‐induced MCP‐1 release by other groups of MAPK inhibitors also regulates opening or closing of both ion channels, but oxLDL mAb seems to inhibit oxLDL‐induced ERK MAPK activity only. This is also coincident with the effect of ERK inhibitor on oxLDL‐induced MCP‐1 release; PD98059 is the best dominant inhibitor compared to the other groups of MAPK inhibitors in inhibition of oxLDL‐induced MCP‐1 release. What downstream molecule