The edges and veins of the leaves are spiny.

A:

Lactuca serriola, Prickly lettuce. Native to Europe and Asia, but it's found almost everywhere now because, as you have found, it's terribly capable of growing wherever it lands. It generally is an annual although there is some potential for them to overwinter if conditions are right. All of your description matches well with the plant including the fluffy seeds.

through concert narration.

The picture would not be complete without Leonard’s activism. In the 60s and 70s, people were afraid to talk about politics, especially when Richard Nixon was president. But Leonard and his wife, Felicia, were committed to making the world a better place and spoke out when they perceived an injustice. The children grew up with that whole sensibility, which is part of who they are today.

The siblings are devoted to keeping their dad’s legacy alive. The centennial provided an unrepeatable opportunity to introduce young people to his life and music. While many young people have not heard of Leonard Bernstein, they are usually familiar with West Side Story. And now a movie remake of West Side Story, directed by Steven Spielberg, is in production. It features


of homosexuality in recent decades. Once gay marriage passed, she thought that most Americans viewed gay people as normal. She believes we’re in the midst of a backlash against gay rights, and it’s as hard to talk about difficult topics today as it was in the 60s and 70s.

When asked about the future of classical music, Jamie referenced her father’s passion for teaching and social justice. Her optimism is fueled by personal experience with El Sistema. Founded in 1975 in Venezuela, El Sistema is a national system of youth orchestras and choirs that lifts children out of poverty and gives them tools for life. The concerts she heard in Venezuela were some of the best she has ever attended. “It was like going to a ball game,” shecommercialization effort. Blank says she wants "a real step-up in ways we engage in the economic development agenda for the state."

During a four-year stint as deputy U.S. commerce secretary, Blank says she learned that economically successful regions attract investment and industries by building partnerships between the public, private and educational sectors — and there is always a large research institution involved.

"The University of Wisconsin-Madison is that research center. It is the ideas factory and the innovation center for the state," Blank said. "It has got to be a partner with the state and with the private sector if we're going to attract the high-tech manufacturing, nutrition, software, health care businesses of the 21st century."

The key job openings Blank will have a hand in filling include director positions at


capital side," Blank said. The University of Michigan in 2011 committed $25 million from its endowment to fund its own start-up companies.

Research spending

UW-Madison's nearly $1.2 billion of research spending in 2012 ranked it sixth among academic institutions such as Johns Hopkins, the University of California System and the Massachusetts Institute of Technology, according to the Association of University Technology Managers, or AUTM.

But UW-Madison ranked 13th for licensing income in 2012 — 30th when adjusted by university research expenses and 40th when adjusted by the number of technology transfer office employees, according to a Brookings Institute report published in November.

And the university started just four companies in 2012, none of which WARF took a stake in, according to AUTM's data. By comparison, in that same year, with less than36.3

1
 Neither Defendant's motion to dismiss with prejudice nor a decision of the district court on that motion is in the Record on Appeal.  Therefore, Plaintiff's request to respond to that motion is not properly before us, and we do not reach that issue


the idea that executive pay should naturally rise when companies grow.

This is a “challenge for the market story,” Frydman said.

So what happened since the ’70s that has sent executive pay upward?

While no company over this period of time — from the 1970s to today — can be considered completely typical, Dean Foods offers a better comparison than most because fundamentally it hasn’t changed.

The dairy business is still the root of the company; it was on the Fortune 500 by the late ’70s and remains there today. It grew then and more recently through acquisition.

Moreover, both chief executives — Douglas and Engles — could boast records of growing the company and profits.

From 1970 to 1979, while Douglas was the chief executive, sales at Dean Foods tripled and profits increasednever gets called but the compiler thinks it does and evaluates the types for you.  And since we are lying to the compiler anyway, we might as well not waste a variable name on the fake instance of Stuff; hence (null! as Stuff).
Let's put that all in one place:
declare function unpartial<T>(t: Partial<T>): T;
interface Stuff {
  foo?: string;
  bar?: number;
  baz: boolean;
  qux: () => void;
}
const unpartialStuff = (true as false) || unpartial(null! as Stuff);
type UnpartialStuff = typeof unpartialStuff;

There you go, you've lied and cheated to fool the compiler to calculate UnpartialStuff from Stuff.  It's up to you if this trickery is worth it in your case.  Good luck!

Update

Can anyone tell me why not?

Well, the reason why it doesn't work is


Report on internal fixation of the femur.
During a recent survey of all cases involving fractures of the femur treated over a four-year period at the Ipswich General Hospital, it was found that a total of 78 were given operative treatment and had some form of metal fixation. This article will deal with these particular cases and summarize the treatment, time involvement and eventual rehabilitation, with consideration given to those which did not follow the general pattern, because of other complications.there will be food, drinks, games, activities, etc. Donations are greatly appreciated and will benefit the Association. If you need more information, contact Nick at (808) 330-8287.

Spring Valley Library Ribbon Cutting ceremony will be held February 28th at Mayer High School. The program will start at 1:30 p.m. Come and welcome this new addition to the community.

Register for the Meals on Wheels National Walk-a-Thon by calling them at 928-632-7511. This will be taking place on March 10th.

U.S.Flag retirement. A bin has been placed at the Mayer St. Vincent de Paul Thrift Store (open Mon/Fri 9A to 4P) for worn U.S. flags. They will be collected by American Legion Post 122 and retired with dignity. If you have a flag ready to be retired, please take it to the


_current_list_index
    _lords_pickle.data['_active_mods_lists'] = _active_mods_lists
    ##: save them also in BashSettings.dat in case someone downgrades - drop !
    bass.settings['bash.loadLists.data'] = _active_mods_lists
    _lords_pickle.save()

def _keep_max(max_to_keep, length):
    max_2 = max_to_keep // 2
    y = length - _current_list_index
    if y <= max_2:
        x = max_to_keep - y
    else:
        if _current_list_index > max_2:
            x = y = max_2
        else:
            x, y = _current_list_index, max_to_keep - _current_list_index
 = __empty
        raise
    finally:
        if cached_lord is not __empty:
            global _current_list_index
            if _current_list_index < 0 or (not __index_move and
                cached_lord != _saved_load_orders[_current_list_index].lord):
                # either getting or setting, plant the new load order in
                _current_list_index += 1


carbon, primarily in waste gases as one or both of the carbon oxides, carbon dioxide (CO2) and carbon monoxide (CO). Carbon oxides from industrial sources are primarily produced by the combustion of fossil fuels and/or chemicals and are classified as greenhouse gases due to their contribution to deleterious environmental conditions. Thus, capturing carbon oxides from industrial gas effluent is both a potentially cheap and scalable way to obtain carbon for biologically mediated chemical production, and a way to reduce the amount of carbon dioxide released into the atmosphere.
Cement manufacture is a major source of atmospheric carbon dioxide, as well as other greenhouse gases. In cement production, a mineral feedstock is progressively heated to increasingly higher temperatures, causing a succession of chemical reactions to take place. One of these<uses-permission android:name="com.google.android.things.permission.USE_PERIPHERAL_IO"/>
    <application android:label="@string/app_name">
        <uses-library android:name="com.google.android.things"/>
        <activity android:name=".SimpleUiActivity">
            <intent-filter>
                <action android:name="android.intent.action.MAIN" />
                <category android:name="android.intent.category.LAUNCHER" />
            </intent-filter>

            <!--
              Uncomment the following intent filter block to enable this activity to


flies were transferred to fresh media vials for egg laying at 25 °C. Eggs laid for the next 1 h were collected and kept at 25 °C for aging until 78 h after egg laying (h AEL).

Dissection of the larval ventral nerve cord {#Sec4}
-------------------------------------------

Larvae aged for a designated time after egg laying (h AEL) were taken out of vials by using a wet brush. They were transferred to a petri dish with a drop of water. The cleaned up larvae were transferred with a drop of 1× Phosphate Buffered Saline (PBS, pH 7.2, 137 mM NaCl, 2.7 mM KCl, 10 mM Na~2~HPO~4~, 1.8 mM KH~2~PO~4~) onto a second petri dish containing Sylgard silicone bed (Sylgard 184 Kit from Dow-Corning Inc. USA). The central nervous system (CNS) containing optic-lobes and the VNC was dissected from the larva300 nm. Therefore, often multiple synapses would appear as a single 3D object in the image. Hence, the total number of such elements would vary widely depending on the squash condition. However, the total number of voxels contributed by all the 3D objects within a neuromeric volume would be consistent. Since regular optical microscopy does not resolve the synaptic junctions, this plugin only helps to estimate the gross area occupied by the synaptic contacts within a neuromere in terms of the number of voxels. We interpreted this volume as a gross estimate proportional to the number of synaptic junctions in the region. The upper limit of the single 3D object was arbitrarily chosen after observing several images.

The conjecture was further supported by the STED imaging which provided nearly 60 nm resolution.


Fig. [4](#Fig4){ref-type="fig"}A-a). The STED images of the same region provided uncharacteristically distributed Bruchpilot staining associated with the bungarotoxin punctae (arrows, Fig. [4](#Fig4){ref-type="fig"}A-b). A similar region of the abdominal ventral nerve cord imaged from the squash-preparation specimen provided a much better clarity (arrows, Fig. [4](#Fig4){ref-type="fig"}B-a) with well demarcated Bruchpilot and bungarotoxin stained zones. The STED images of the same region highlighted clear Bruchpilot punctae juxtaposed to the bungarotoxin stained ones as expected (arrows, Fig. [4](#Fig4){ref-type="fig"}B-b). The spatial correlation between the Bruchpilot and bungarotoxin staining amongst the confocal and STED images were very good in the squash-preparation specimen. It was further highlighted by the 3D object counting analysis using Fiji^®^.Fig. 4Confocal and Super-resolution imaging of Bruchpilot and Bungarotoxin staining in the whole mount and squash preparations. **A** Whole-mount preparation and **B** squash preparation of abdominaldescribed above could provide a significant improvements in the data quality obtained from both the Super-resolution and confocal images.

Individual synaptic boutons cannot be resolved by conventional optical microscopy in the CNS due to their compact organization \[[@CR39], [@CR40], [@CR42]\]. Therefore, no good assay is established yet for quick assessment of synapse number in whole CNS. Hence, results from neuromuscular studies were extrapolated to CNS, since it was assumed that central nervous system defects would be manifested in NMJs. However, that does not hold true in the case of axonal transport deficits. For example, kinesin-2 mutations show aberrant axonal transport of its cargoes viz. Choline acetyltransferase, Acetylcholinesterase and Rab4 in *Drosophila* sensory neurons \[[@CR51], [@CR52], [@CR64]--[@CR66]\]. However, they do not directly affect synaptic bouton formation in the NMJs \[[@CR67]\],


positive reviews, the track record of the team, etc.

Blockchain.io

If there is any ICO you should take serious in this remaining part of 2018, it should be Blockchain.io and this is because the platform is already popular and highly trusted. Blockchain.io is a cryptocurrency wallet and exchange with great reputation and without incidences of hacking.

Category: Crypto-Exchange

Date: 27 Sept to 25 Oct 2018

Whitepaper: https://blockchain.io/wp-content/uploads/2018/05/BCIO_Manifesto.pdf

Hard cap: 20,000,000 EUR

Token price: 1 BCIO = 0.7 EUR

Network: Ethereum

Telegram: https://t.me/blockchain_io_channel

About Blockchain.io

Blockchain.io is an all-inclusive network that provides secure and efficient access to the Internet of Value. Its main aim is to emerge as the principal cryptocurrency exchange in Europe by 2020. It plans to make altcoin and crypto listing facilities including ICO services available to the public.

Additionally, Blockchain.io will provide features that will enhance comprehensivesurvey questions, the BLS place adult population in 3 groups o Employed: paid employees, self employed, and unpaid workers in a family business. In particular, a person is considered employed if he or she has

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= os.path.dirname(dest_to_write)
    path = path.replace("/","\\")
    # Change directory
    cmd = "cd " + path
    response = cb_injector.injection(separator, TAG, cmd, prefix, suffix, whitespace, http_request_method, url, vuln_parameter, alter_shell, filename)
    # Find filename
    filname = os.path.basename(dest_to_write)
    tmp_filname = "tmp_" + filname
    cmd = settings.FILE_WRITE + content + ">" + tmp_filname
    if not menu.options.alter_shell :
      cmd = "\"" + cmd + "\""
    response = cb_injector.injection(separator, TAG, cmd, prefix, suffix, whitespace, http_request_method, url, vuln_parameter, alter_shell, filename)
    # Decode base 64 encoding
    cmd = "certutil -decode "  + tmp_filname + "The present invention relates to a system for remote monitoring, and for the communication to a user remote from the monitored location. It is of particular but by no means exclusive use in the areas of security monitoring of, for example, sites such as domestic premises, industrial premises or vehicles.
Existing remote monitoring or alarm systems are triggered by, for example, a security breach, such as when an intruder triggered a motion detector or other sensor. An alarm condition is thereby established, causing an alarm indication signal, indicating that the alarm condition exists, to be transmitted to a remote monitoring site. The alarm indication signal may then trigger a bell, light or the like at that remote monitoring site. In some systems, a person at that remote site can


a bit of modeling.

I always love shooting in new locations, especially interesting new locations. The campus at Penn lacks no character, space, architecture, or visual interest of any kind. It’s a really great atmosphere. On campus has a certain look and feel, and only a few block from campus a very different look and feel, I love it! Versatility of location is always a major plus.

Wandering

We began the afternoon (very sunny afternoon) by wandering around outside of Penn first and explored some alleyways and streets and ventured onto the college grounds. Andrew was a rock-star, we took advantage of a construction site, empty café, and paparazzi’d a few random students (some of the best photos of the day, just kidding ;) ) and he killed it on campus,in the chances of offspring inheriting identical forms of a gene from both parents, known as genetic homozygosity. This reduces people's genetic fitness, so "Habsburg jaw" should be considered a recessive condition.

However, the authors note that the study involves only a small number of individuals so it's possible that the prevalence of Habsburg jaw is due to the chance appearance of traits, or genetic drift. They suggest this scenario is unlikely, but can't rule it out.

"While our study is based on historical figures, inbreeding is still common in some geographical regions and among some religious and ethnic groups, so it's important today to investigate the effects," says Vilas. "The Habsburg dynasty serves as a kind of human laboratory for researchers to do so, because the range of inbreeding


ASHTON Series 5-Pocket Pencil Case - Pink

KAGS decided also to design pencil cases while we see a need for the children to have a more practical and more organised pencil case than those in the market. So we came up with Ashton series pencil cases. Practical, good in size, fits most stationery and accessories the children need for school. It has 5 different compartments for them to locate everything properly. In addition, we have 4 different colour combinations so there would definitely be something they like. Ashton Series Pencil cases are made with water repellent PU coated sturdy polyester to offer your children extra protection for their stationery.The photo above shows her in front of the "separation barrier" at Gilo. The US press insists on calling Gilo a "Jerusalem neighborhood," but in fact, it is in fact an illegal Israeli settlement on West Bank land.

Meanwhile, the moderator of the Church of Scotland's General Assembly, David Lacy, has just spent two weeks in Israel and the Palestinian territories. After viewing the same wall that the Senator saw, he remarked,"when you actually see where it is, you see that it's not for security, it's for making political statements. It's theft of land and I don't know how you can justify it on the grounds of anti-terrorism." Lacy went on to say the barrier is "a huge, horrible, oppressive sign of distrust and hatred in the birthplace of


take out in 1979, was married to Georgina Rizk, the Lebanese Miss Universe (1971), shown above in hotpants.

Sen. Hillary, a member of the Senate Armed Services Committee, is off to visit Israel next week, to meet with PM Sharon and deputy PM Peres. The purpose, says the New York Times, is "to discuss American-Israeli relations, in a trip that may help her strengthen her support among Jews in New York as she faces re-election next year." As a taxpayer, I'm glad that I can help out with this important project. Hillary will "reiterate her condemnation of remarks made by President Mahmoud Ahmadinejad of Iran calling for the destruction of Israel." Isn't that brave of her? And she will visit a portion of the "security fence" (a.k.a. separation barrier,Canvas Guides, etc).

2. If you are not in Canvas a. Call (855) 778-9969 b. Live Chat, File a Ticket, Search the Canvas Guides, or Request a Feature on the Canvas Help site.

Canvas Accessibility Statement

Canvas adheres to US Section 508 accessibility standards, and is committed to the Web Accessibility Initiative's (WAI) guidelines for content (WCAG) and rich internet applications (ARIA) as documented in our Voluntary Product Accessibility Template (VPAT), which is publicly available at http://www.instructure.com/accessibility.


= 'Word';

var words:XMLList = list.mylist.category.(@cat == 'klank').word;

// Loop over the word nodes from the selected category
for each(var word:XML in words)
{
        // Find the node with value matching curWord
    if (word.text() == curWord) {
        trace(word.@aw);
    }
}

[
    {
        "type": "feature",
        "category": "",
        "description": "Retry on a set of CURLE_*_ERROR based failures. Currently, only CURLE_RECV_ERROR (errno 56) is retried."
    },
    {
        "type": "enhancement",
        "category": "Api\\Parser",
        "description": "Simplify return."
    },
    {
        "type": "api-change",
        "category": "Budgets",
        "description": "Add additional costTypes: IncludeDiscount, UseAmortized, to support finer control for different charges


some of the data—the report also shows that 53 percent of those requests were American civil subpoenas.

Presumably this included a March 2014 subpoena that Ars previously reported on from the Delaware Attorney General’s office, which sought “all records and information including registered name, e-mail, and IP address" concerning user “un1cornbl00d ” for a certain two day period at the end of that month. State authorities wanted this information in an attempt to locate a man and woman who appeared (NSFW) to have sex in public in the town of Newark, Delaware, on St. Patrick’s Day, March 17, 2014.

The company also said that it has never complied with any of the five foreign requests where user data was asked for.

Reddit continued:

Many government requests we receive contain demands to withholdthe surface must produce a  stray field, $H$. In short, the production of the stray field corresponds to a cost in energy $\frac{1}{2\mu_0}\int H^2 dV$ which can be minimised by reducing the amount of $M$ which terminates at the surface. The consequence is that the minimum energy state for the magnetic order is certainly not for all the spins to align with one-another in most cases. This is why we see twists and turns in the magnetic order, 'Domain structure'.
So basically, the exchange interaction provides a method for spins to align with one another on the short scale and the minimisation of the stray field shapes the larger structure across whole domains. (Other contributions can come from external magnetic fields and magneto-crystalline anisotropy).
I may have gone off


The present invention relates to an electronic apparatus having a voltage converting circuit for converting the voltage of power supplied by an electricity supply device and operated by power outputted from this voltage converting circuit.
FIG. 12 typically shows the schematic construction of a conventional electronic apparatus. As shown in FIG. 12, the conventional electronic apparatus is constructed by a voltage converting circuit 702, a control circuit 105 and a load circuit 104. The voltage converting circuit 702 outputs fourth power 109 by converting the voltage of first power 106 supplied from an electricity supply device 101. The control circuit 105 detects the voltage of second power and outputs a control signal 710 to control an operation of the voltage converting circuit 702 such that the fourth power 109caused particularly when the load circuit 104 is an IC having an operating mode having a large consumed electric current and a violent variation of the consumed electric current, and a standby mode having a small consumed electric current and a small variation of the consumed electric current, and is an IC for a portable telephone having a receiving-transmitting mode having a large consumed electric current and a violent variation of the consumed electric current, and a waiting mode having a small consumed electric current and a small variation of the consumed electric current. The number of cases adopting the IC of such a type in the load circuit 104 is recently increased, and the number of cases causing the above problem is increased in recent years.
The above


and the waiting mode, etc. to improve performance and reduce power consumption. Therefore, the above problem becomes more serious.
Therefore, a main object of the present invention is to provide an electronic apparatus in which a load circuit having an operating mode extremely different in a consumed electric current and a consumed electric current variation can be efficiently operated by converted power from the electricity supply device.
In a first construction of an electronic apparatus in the invention, the electronic apparatus comprises electricity supply device for supplying power; a voltage converting circuit for converting the power to converted power different in voltage from the power and outputting the converted power; a control circuit for controlling an operation of the voltage converting circuit such that the converted power becomes predetermined desirable100% technology: lithium-ion

Use apci command to check battery status using terminal

The acpi command may not be installed by default so use apt-get command or yum command to install the same:

$ sudo yum install acpitool

OR

$ sudo apt-get install acpitool

Sample outputs from Ubuntu LTS 12.04 laptop:

Reading package lists... Done Building dependency tree Reading state information... Done The following package was automatically installed and is no longer required: nvidia-settings-experimental-310 Use 'apt-get autoremove' to remove them. The following NEW packages will be installed: acpitool 0 upgraded, 1 newly installed, 0 to remove and 4 not upgraded. Need to get 46.3 kB of archives. After this operation, 156 kB of additional disk space will be used. Get:1 http://in.archive.ubuntu.com/ubuntu/ precise/universe acpitool amd64 0.5.1-3 [46.3 kB] Fetched 46.3 kB in 1s (37.6 kB/s) Selecting previously


here at Cara's desk working on this essay, of having to introduce my jelly to a new person who is likely to scrutinize and reject it makes me feel like an asshole. I just don't want to do that anymore. Can't we just lie fully clothed in bed together while holding hands and talking about how good pork belly tacos taste? I don't want to do the "I'm sorry this is my disgusting body" apology jig ever again, nor will there ever be a time that the "just let me keep my shirt on" waltz isn't utterly humiliating. Why must they always argue? Just let me keep this stupid long-sleeved shirt on already.

Left Leg:

1. Dark brown leather burn from fancy-ass North Face boots three inches above ankle.

2. Darkmake a choice to welcome the day, and we can make it a day dedicated to doing what God has called us to do for His Kingdom. Instead of greeting Mondays with a strong dislike, how about we meditate on the Word as we start each week? Joshua 1:8 says, "This Book of the Law shall not depart out of my mouth, but I shall meditate on it day and night, that I may observe and do according to all that is written in it. For then the Lord shall make my way prosperous, and then I shall deal wisely and have good success." My personal Scripture verse for the year is this:"And in this I give advice: It is to your advantage not only to be doing


for example, a layer of photoresist is formed on the surface of the semiconductor chips and patterned by developing the photoresist and washing away the unwanted portion of the photoresist. Because the metal lines and other metal structures have xe2x80x9ccriticalxe2x80x9d dimensions, that is, dimensions that can affect the performance of the semiconductor chip, the process of forming the photoresist pattern for each layer is examined during the manufacturing process. Some of these process steps involve placing the wafer in which the semiconductor chips are being manufactured into different tools during the manufacturing process. The optimization of each of these process steps requires an understanding of a variety of chemical reactions and physical processes in order to produce high performance, high yield circuits. The ability to view and characterizedefine standard random library functions. The most well-known are probably the rand() and srand() functions.
Since...

While you can develop software using just a text editor and the command line (and many people do), you'll often see productivity gains by using a graphical integrated development environment (IDE). Here are a few options for IDEs that are suitable for Qt development.
Qt Creator
The "official" Qt IDE, Qt Creator (1) is open source, cross-platform, and written using Qt. It is usually the IDE of choice for Qt development unless you have some special requirements or a personal preference. Its support for mobile and embedded platforms really pays off in making it easy to build, deploy,...

Various tools that can be lumped together under the category of simulators and emulators can be useful during development,


are available in this environment, as well. While the final product may not ship with them, as a developer you can have access to a shell, basic commands,...

Memory and resource leaks are the stuff of nightmares for programmers. If a program doesn't properly free memory or other resources, it may appear to run correctly, but randomly crash or misbehave after working normally for hours or days. All too often, the problem is only discovered just before the application is supposed to be shipped to customers.
While Qt helps somewhat with it's object model, resource leaks can occur with any programming language like C++ where the user is responsible for managing memory or other resources like file handles. Let's take a look at some of the tools that...

Static Analysis (1),controller and two XBee wireless modules in conjunction with a Qt-based application.
Part 1 provides an overview, demonstrates communication between two applications using the XBee, and describes the hardware setup. Part 2 covers the configuration and programming of both the desktop application and the Arduino code.
Introduction
There are many different XBee models available with various wireless protocols, line of sight ranges, data transmission rates, RF...


as was also the TxB2 production by platelets. When the subjects were divided into normotensive and hypertensive ones, unexpectedly, basal plasma values of catecholamines were higher in normotensive volunteers but TxB2 production was more marked in hypertensive subjects.aesthetics to clinical practice, the Anton Proksch Institute's Orpheus Programme is concerned with opening up spaces and creating atmospheres in which it becomes possible for the individual addicts to realise their possibilities. The challenge in the therapeutic process is not only to recognise the significance of the disorders' pathology but also to find ways out of the imagined impossibilities by opening up new possibilities and uncovering resources of the suffering human.


such I find it highly likely that you would eventually have differing non-functional requirements for both. To be able to allow differing configuration for these, you will have to use distinct Event Processor instances for both. The Event Processor, the component in charge of managing the technical aspect of providing the events to your event handlers, as the place to configure things like exception handling, threading numbers, batch sizes, etc.
Note that Event Processors come in two flavors: the SubscribingEventProcessor and the TrackingEventProcessor. These can shortly be described as an event push and an event pull mechanism, with the latter being the default as it enforces further segregation.
To configure distinct event processors for both, you can either use the Configuration API provided by Axon. For Event Processor, thatfile redirection:
echo 'SELECT * FROM tbl' | mysql --user=user dbname
# Or:
mysql --user=user dbname < file_containing_queries.sql

For your application in Capistrano, executing them via --execute should work well. You may delimit multiple statements with semicolons, but be sure to properly quote everything. The full set of SQL statements should be one quoted string.
# In a Capistrano task:
execute "mysql -e'SELECT * FROM tbl1; SELECT * FROM tbl2;' -u <username> -p <password> -h <server ip> <database name>"

This may be a good use of Ruby's alternative %q/%Q quoting to avoid issues quoting string literals inside the SQL statements:
execute %q{mysql -e"SELECT * FROM tbl1 WHERE col='value'; SELECT * FROM tbl2 WHERE col='value';" -u user -ppasswd -hhost dbname}

When launching the mysql client via SSH in Capistrano, it appears that the client is loaded on the


your oven to warm, and set cooling racks over paper towel-lined cookie sheets inside the oven. You will probably need two racks.

Start fat heating in a deep, 2-quart saucepan. You’ll need several cups of fat, and this is why I prefer using a deep saucepan with a small bottom rather than a cast iron skillet. You can get a deep fryer effect with less fat. The fat should be at least 4 inches deep in the pan when melted/heated. If you happen to have a deep fryer, follow manufacturer’s instructions for using.

It’s wise to have a candy thermometer or digital thermometer to monitor the heat of the fat. The fat should come up to between 350 and 360 degrees. (Hotter than that, and this delicate batter coating willlunch dish, is key. However, when I was planning to test this recipe, I forgot that the dough was supposed to sit for 8 hours, and I didn’t get it started until 11 o’clock in the morning. I figured I’d cover the bowl with plastic wrap and put the dough by the heating stove and see what happened in the time I had. I was very surprised that in just 4 hours, the dough had more than doubled in size.

I took half of it out of the bowl (and I had only made half a recipe anyway because I didn’t want to sacrifice 6 eggs on an experiment) and rolled it for noodles for the turkey soup. I covered the rest of the dough and left it sitting


dismal report card on U.S. schools has sparked a call for national standards. As a first step, Education Secretary Richard W. Riley unveiled “Goals 2000” last April. It promised, among other things, to make U.S. students “first in the world in math and science.” “We are looking at the world because it’s a global economy,” Riley told Mother Jones. “But we are mainly looking at ourselves.”

Unfortunately, Riley’s bill seems more fixated on schools than on the people they are supposed to serve. The “opportunity to learn” standards say almost nothing about testing students on what Americans decide they should know. Instead, a new agency and various provisions seem intended to give Washington more muscle in regulating teachers, textbooks, and curricula–quite a coup for a national government that fundstransgender people
More than three months after authorities misidentified a transgender woman who was shot and killed outside her home, an Austin city commission on Monday unanimously voted in favor of a resolution that would direct the city to begin exploring how Austin police can better identify members of the transgender and gender-nonconforming community.


constitutions guarantee some form of voting rights. In 2018, the Pennsylvania Supreme Court that had rejected William Fogg’s voting rights suit in 1937, struck down the state’s congressional gerrymander and adopted a fair map for the 2018 elections.

Ultimately the future of voting rights depends on the will and the activism of the American people. Americans must look past the smokescreen of voter fraud and demand opportunities to register and vote without undue restrictions. Despite the lack of a federal constitutional guarantee, the right to vote remains the bedrock of all other rights in a democratic nation.

Allan J. Lichtman is Distinguished Professor of History at American University in Washington, D.C. and author of "The Embattled Vote in America: From the Founding to the Present." Follow him on Twitter: @AllanLichtmansees no reason why Delray itself could not request the STB to revoke its exemption only for the purpose of determining whether Delray should be exempted from the Coal Act.[12]
In fact, although it criticizes Delray for not objecting at the time the STB published the notice of exemption, Delray itself could have taken earlier action. Delray has not explained why it was not entirely foreseeable that obligations under the Coal Act might apply to Delray, thus, rather than seeking exemption of the transaction, U.S. Steel could have requested the STB to investigate and make a decision regarding the Coal Act in the first place. Anticipating the court's thinking, Delray argues that, at the time U.S. Steel sought exemption of the Delray acquisition, it provided required information to the


getup: “I see a red bottom and it’s not a shoe”; Katya’s fur trapper outfit with a dead beaver on her head; Pearl’s don’t-give-a-shit runway stagger and headphones. Lowlights: Tempest’s quilted poncho and lumberjack-ian wide-legged stance; Sasha Belle’s gross red dress, which the judges compare to a lobster, but I think is more reminiscent of Snarf; Alaska as a witless Anna Wintour impersonator.

NEXT: A whole new panel of judges

After the Maxi-Mini Challenge, the queens take of their makeup for the first time, surprising each other with their male identities. Pearl is actually super-cute—the sort of guy you see rocking jorts at Metropolitan in Williamsburg—Trixie Mattel is the long-lost fourth kid from Roseanne, and Tempest is a dad who used to weigh 400 pounds. Katya shoots off a greatCorbyn, transparency and parliament.. Here is the summary of what was said on the forum thread.

Peter Macfadyen, Campfire member and our guest on our forum sofa this coming Tuesday (October 10th) at 20:00 is a town councillor and one of the architects behind Flatpack Democracy, a DIY guide to creating independent politics. His story is an extraordinary one.

Our third sofa sessions guest was DJ and blogger Greg Wilson who played at the first Campfire Convention and has recently launched his Super Weird Substance website. He talks about his earliest influences, musical eclecticism , dancing as meditation, Liverpool and MuMuification, amongst other things.

Campfire welcomes our first DJ guest Greg Wilson to our forum sofa on Tuesday 26th September (20:00) to talk about 'Joining the dots of UK dance culture'


Preprocedural TIMI flow and mortality in patients with acute myocardial infarction treated by primary angioplasty.
The aim of the study was to evaluate the impact of preprocedural Thrombolysis In Myocardial Infarction (TIMI) flow on one-year mortality in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary angioplasty. Although there is an excellent outcome conferred by primary angioplasty in patients with STEMI, the prognostic role of early recanalization in these patients has yet to be investigated. Our population is composed of 1,791 patients with acute myocardial infarction treated by primary angioplasty at our institution from 1994 to 2001. All angiographic, clinical, and follow-up data were prospectively collected. According to the TIMI risk score, patients were stratified in low- and high-risk groups. Preprocedural TIMI flow was related to postprocedural TIMIto 70% after reperfusion in the OG-VI group. The creatine phosphate (PCr) / inorganic phosphate (Pi) was maintained the baseline level and did not decrease after hypoxia in the OG-VI group while PCr/ Pi was decreased after hypoxia in normal rat. These data suggested that the nucleoside-nucleotide (OG-VI) improved nitrogen metabolism and might stimulate synthesis of high-energy phosphate in recovery after severe surgical stress.


"event" to an event that is triggered later in the page life cycle and before Render is triggered. The safest place would be OnPreRender as shown below...
    public string BigText { get; set; }
    public string SmallText { get; set; }
    public Color BigTextColor{get; set;}
    public bool ArrowUp{get; set;}
    public string SubBigText{get; set;}

    protected override void OnPreRender(object sender, EventArgs e)
    {
        base.OnPreRender(e);

        lblBigText.Text = BigText;
        lblSmallText.Text = SmallText;
        lblBigText.ForeColor = BigTextColor;
        lblSubBigText.ForeColor[Role of peripheral adrenergic links in the development of antidepressive effect in an experimental model of behavioral depression in rats].
The study was made on the reserpine model of behavioural depression in cats. The morphofunctional state of peripheral adrenergic nerves in control experiments and under action of antidepressants (befol and nialamid) was studied by fluorescent microscopic method. One definite correlation was shown between the state of somatovegetative changes and the level of neuromediator activity of the adrenergic structures. It was established that the used antidepressants (more expressive by befol) have protective effect in depressive conditions.


Advances in the molecular genetics of non-syndromic polydactyly.
Polydactyly is one of the most common inherited limb abnormalities, characterised by supernumerary fingers or toes. It results from disturbances in the normal programme of the anterior-posterior axis of the developing limb, with diverse aetiology and variable inter- and intra-familial clinical features. Polydactyly can occur as an isolated disorder (non-syndromic polydactyly) or as a part of an anomaly syndrome (syndromic polydactyly). On the basis of the anatomic location of the duplicated digits, non-syndromic polydactyly is divided into three kinds, including preaxial polydactyly, axial polydactyly and postaxial polydactyly. Non-syndromic polydactyly frequently exhibits an autosomal dominant inheritance with variable penetrance. To date, in human, at least ten loci and four disease-causing genes, including the GLI3 gene, the ZNF141 gene, the MIPOL1 gene and**INTRODUCTION:** The increasing use of autologous fat grafting (AFG) in breast cancer patients has raised concerns regarding its potential to obscure radiographic monitoring and enhance cancer recurrence. Given the paucity of strong data addressing these concerns, this study evaluates patient outcomes and tumor recurrence following oncologic resection and AFG.

**MATERIALS AND METHODS:** Retrospective chart review identified patients who underwent oncologic resection for breast cancer or carcinoma in situ, followed by breast reconstruction, from 2010 to 2015. 524 patients met inclusion criteria: 148 (28.2%) patients underwent AFG (test group), while 376 (71.7%) patients did not undergo AFG (control group). Patient demographics, cancer characteristics, oncologic treatment, surgical treatment, surgical complications, local recurrence, and distant metastases were analyzed.

**RESULTS:** Both patients who underwent AFG and those who did not were of similar BMI,


[Incretin and incretin-based therapies].
GIP and GLP-1 are major incretins and secreted from K-cell and L-cell in response to meal ingestion, respectively. GIP and GLP-1 potentiate glucose-induced insulin secretion by binding GIP receptor and GLP-1 receptor, respectively, on pancreatic beta-cell and increasing intracellular cAMP concentration (incretin effect). GIP receptor and GLP-1 receptor are expressed in some different organs. GIP receptor is expressed in intestine, adipose tissue, brain, adrenal gland, and bone, while GLP-1 receptor is expressed in intestine, CNS, lung, kidney and heart. GIP and GLP-1 have not only pancreatic effect, such as potentiation of insulin secretion, but also many extrapancreatic effects. Incretin effect is known to be decreased in type 2 diabetes patients compared to that in healthy subjects. GLP-1 was target peptide as anti-diabetic drug, because insulinrecommend).

Long story short, all these events have shown that it's possible to take over blockchain networks for potentially malicious reasons, and there may be a couple of reasons for doing as so.

Motives/Attacks

Why would anyone want to take over/break a blockchain? I envision a couple of reasons:

Goldfinger Attacks: Some people just wanna see the world burn (see "On hostile blockchain takeovers" [4])

Governance Takeovers: An imbalance in incentives lead to the Great Bitcoin Scaling Debate of 2015-2017. Different groups of actors in the system (various miners, users, wallets, etc.) wanted to control governance of the protocol to limit/move forward an upgrade. This could happen even more in the future as various blockchains stop being maintained.

Competitive Chains: Chains that solve similar usecases will ultimately compete for developers, users, investors to determine


multisig control of a DAO splits? (alternatively, what happens when a token forks?)

What happens to a DAO when the base Ethereum protocol has a network split (resulting in two different coins)?

What is economic finality in Casper, and what does it achieve/solve compared to Nakamoto consensus?

What's the difference between Casper, the Friendly Finality Gadget and Casper, Correct-by-Construction?

What is a slashing condition?

What are long-range attacks and the nothing-at-stake problem, and how are they subverted?

Where do the slashed Ether deposits of byzantine nodes go when not following the Casper protocol?

What is a "layer two" system, and how is security guaranteed without a blockchain?

Lightning Network is a project involving payment-specific state channels. How does this work generalize to Plasma?

Ethereum recently added support for zero-knowledge proofs. How does it solve the trusted setuptwitter @niraj.

]]>
Niraj Panttag:blog.niraj.io,2013:Post/11748962017-08-10T00:20:59Z2017-11-09T05:36:13ZARKit and the mainstream adoption of AR

ARKit has been getting a ton of attention recently, and rightly so. Several demos showcasing the technology from @madewithARKit have been going viral on twitter. I believe it's the most exciting thing in the AR/VR space since the Oculus Rift first came out. For some background, ARKit is an iOS 11 SDK that provides powerful, low-level access to camera/location sensor data for high-quality augmentation1. It was recently announced at WWDC 2017, and is currently available in beta preview to iOS developers, allowing them to get accustomed to the technology before the stable release this fall.

ARKit allows anyone with iOS programming experience to build AR applications on the iPhone. Typically, AR has been slow to customer adoption because: 1) expensive hardware


package. Ditto for sleep tracking, GPS, crowdfunded maps, and sending data through the audio port. The iPhone (probably) wasn't designed with these applications in mind, but the platform is modular enough to allow them.

ARKit similarly holds this same potential for interesting non-traditional use cases. I'm excited for simple measuring tools (who carries around a ruler with them???), placement of shopping products in your home, and even more intimate guided city tours. See:

I've been interested in this space for a while. A broad prediction I have for the coming years is that, as a developer, you won't need to be proficient in machine learning to take advantage of its power. The technology is becoming increasingly democratized and opening up access to millions of new developers. Eventually, you won't eventools were abstracted into frameworks (Perl, Ruby on Rails, Bootstrap) and tools (AWS, Heroku, Parse), making the process of building, deploying, and scaling much easier. Taking it one step further, tools are even being built for non-developers to build apps (Treeline being a good example).

In the machine learning world, we're moving away from the TCP/IP days into the Ruby on Rails days. With limited ML background, it's now much easier to build ML applications than it was even a few years ago. With the rapid development of new open source toolkits, we're truly seeing a rapid commoditization of the technology:

2010-2014: a new deep learning toolkit is released every 47 days. 2015: every 22 days. tensorflow & caffe top github pic.twitter.com/fJ7JESxlip

The Ruby on Rails of ML is toolkits like


15-Year-Old Denied Heart Transplant for “Non-Compliance”

Fifteen-year-old Anthony Stokes’s family says he’s been unfairly denied a lifesaving heart transplant because of his failure to keep up with his medicine and doctor’s appointments.

While the Children’s Healthcare of Atlanta hospital has declined to comment on Stokes’s case, it explained via a statement: “We follow a very specific criteria in determining eligibility for a transplant of any kind.”

Stokes’s family friends have said they think the “non-compliance” excuse is nonsense, pointing to his bad grades and past run-ins with the law as the real reason why “they don’t want to give him a heart.”

Yet, as the president of the American Heart Association has pointed out, an ability to keep up with medication is a vital requirement for a heart transplant. “You have to126 S. Ct. 1925 (2006).               Where, as here, the motion was

based on a claim of insufficient evidence, the verdict of a jury

must be sustained if there is substantial evidence, taking the view

most favorable to the Government, to support it. Glasser v. United

States, 315 U.S. 60, 80 (1942).               We find the jury’s verdict was

supported by substantial evidence.

          Finally,      we     find    no    error     in    the    district


court’s

decision to deny McLachlan’s request for a jury instruction for

“innocent possession” of the firearm at issue.                     We have previously

rejected this instruction in § 922(g) cases.                        United States v.

Gilbert, 430 F.3d 215, 218-20 (4th Cir. 2005).

          Accordingly, we affirm.              We dispense with oral argument

because the facts and legal contentions are adequately presented in

           epidemiologic studies in different provinces and cities of Iran, the most common mental disorders in Iran are mood and anxiety disorders. In some studies, mood disorders, including depression, and anxiety disorders, including generalized anxiety disorder, obsessive compulsive disorder, and phobias, have been reported as the most common disorders in Iran ([@ref19]). Considering the high prevalence of these disorders in Iran and other countries, the evaluation of web-based information about mental disorders is necessary to determine the validity of the websites and rank them for users.

Therefore, in this study, Persian mental disorders websites relating to three widespread disorders in Iran---depression, anxiety, and obsession---were evaluated based on the WebMedQual scale. This study aims to help patients choose reliable websites for obtaining information about the identification and treatment of mental disorders.


investigating after a Jefferson City corrections officer allegedly participated in the challenge and wrote “Feeling cute. Might take your homeboy to the hole later.”

Matthew Elliott, a spokesperson with the Oklahoma Department of Corrections, says the department is investigating.

“We’ve been monitoring the posts since they began. All employees who participated in the posts you mentioned have been reprimanded for failing to represent the mission of this agency. We’re continuing our investigation and may take additional action,” Elliott says in a statement.

“Corrections is a serious matter. Beyond the extremely poor judgment shown by these officers, being flippant about mistreating inmates, even if it’s intended as a joke, puts these staff and their fellow officers at risk. This is no laughing matter.”

Officers with Texas’ Aransas Pass Police Department also took parttake advantage of the strength of our faculty and curriculum by taking multiple courses in the arts, humanities, languages, the social sciences, and natural sciences. You will graduate four years from now better educated and just as prepared to go on for a Ph.D. or to pursue any career you wish as you would have been had you completed a double major.

More importantly, by taking courses broadly across the curriculum, chances are you will happen upon a faculty member who will excite you with material you otherwise never would have encountered, and perhaps change your life. Science majors might find Classical Greek poetry, John Stewart Mill’s “On Liberty,” or landscape painting central to the rest of their lives, just as literature majors might discover a passion and life-long


interest in ecology, marine life, or the study of the human genome.

As you think about the next four years, then, try to think about striking a balance in what you study, in what you do outside your academic work, and in what you do for a social life. Contrary to how it might seem from afar, the transition to college is never seamless for anybody. And don’t procrastinate; jump right in. Finding a significant connection to something here and finding it early—an athletic team, an a cappellagroup, a literary club, or any of the College’s 140-plus student organizations—will provide the kind of social entrée that will make the transition here easier and far richer.

This, too, takes initiative, but we make it relatively easy to take that initiative: Iperformance and falls, what impact on patient's community participation and independence. Therefore, it is important to conduct a study with larger samples, to further investigate the interaction between motor-cognitive variables. The purpose of the current study was to examine the relationship between motor and cognitive symptoms, determining which motor parameters are most strongly associated with cognitive parameters in PD patients.

METHODS
=======

This was a cross-sectional study. Patients with a PD diagnosis according to the criteria of the UK Brain Bank were recruited.[@B17] These patients had attended the neurological rehabilitation inpatient or outpatient program at the SARAH Network of Rehabilitation Hospitals (Brazil). Inclusion criteria were: age greater than 50 years, educational level greater than 4 years, no psychiatric disorders prior to the diagnosis of PD, as well as no history of


 rSp =0.2731 (p=0.0278[\*](#TFN3){ref-type="table-fn"})       -0.2448 (0.0494[\*](#TFN3){ref-type="table-fn"})     -0.01 (0.9367)
  FAS (total)                       rSp =0.0198 (p=0.9075)                                       0.2545 (0.1285)                                      -0.1276 (0.4517)
  TMT-A (seconds)lines and senses the differential between the two lines (responsive to the clock input SACLK) to generate the output line (Dout). Two additional NMOS transistors may be added for each additional driver (having gates coupled to receive the dynamic data signal and its complement from that driver).
FIG. 2 illustrates a second prior art circuit which may be used to handle multiple drivers of a line (Dout). The circuit of FIG. 2 may sometimes be referred to as a single-rail dynamic circuit. In FIG. 2, each driver may drive a dynamic data signal (e.g. the dynamic data signal d0 may be driven by a first driver and the dynamic data signal d1 may be driven by a second driver). Similar to FIG. 1, the dynamic data signals are precharged


such that $\mathcal{F}_{x_{0}}=0$. The motivation to study these systems come from the need to formalize concepts involved in control theory on manifolds that transfer several issues, such as the controllability, to be treated in more pleasant state space such as Lie groups.

About the structure of this paper, in the second section we introduce the notion of orbit equivalence and topological conjugacy for semigroup actions and give some properties related with control sets. In the third section we fix the control theoretic notations and relates state equivalent control systems with diffeomorphic control systems. In the fourth section we prove that given a control system on $M$, the semigroup system on $M$ is orbit equivalent to a semigroup action on a homogeneous space. In the last section we prove ourand $(M_{2},T)$ are called orbit equivalent, if there exists an homeomorphism $f:M_{1} \rightarrow
M_{2}$ such that $f(Sx)=Tf(x)$ for all $x \in M_{1}$. The map $f$ is called orbit equivalence map.

Some authors call the pair $(M,S)$ as transformation semigroup (see e.g. Ellis in [@ellis] and Sousa in [@josiney])

Locally, we have that the actions $(M_{1},S)$ and $(M_{2},T)$ are called orbit equivalent restricted to a subset $C
\subset M_{1}$ if there exists an homeomorphism $f:M_{1} \rightarrow
M_{2}$ such that $f(Sx)=Tf(x)$ for all $x \in C$.

Now supposing the existence of control sets we give some properties of orbit equivalent actions. Recall that taking the topological space as flag manifolds, there exist always control sets (see e.g. [@san; @martin] and [@san; @martin; @e; @tonelli]).

\[preservecs\] Suppose that $(M_{1},S)$ and $(M_{2},T)$ are orbit equivalent. Hence if $C_{S}$ is


V., Tirao J. Linear control systems on Lie groups and local controllability. Differential geometry and control (G. Ferreyra, R. Gardner, H. Hermes, and H. Sussmann, Eds.) Amer. Math. Soc., Providence, Rhode Island. 1999; 47-64.

Colonius F., Kliemann W. The Dynamics of Control. Boston: Birkhäuser 2000.

Elliott D.L. Bilinear control systems: Matrices in action. New York: Springer 2009.

Ellis R. Cocycles in topological dynamics. Topology. 1978; 17: 111–130.

Jurdjevic V. Geometric control theory. Cambridge: Cambridge University Press 1997.

Rocio O.G., San Martin, L. A. B. and Santana A. J. Invariant cones and convex sets for bilinear control systems and parabolic type of semigroups. J. Dyn. Control Syst. 2006; 12: 419-432.

Rocio O.G., Santana A. J. and Verdi M. A. Semigroups of Affine Groups, Controllability of Affine Systems and Affine Bilinear Systems in ${\rm Sl}(2,{\Bbb R})\rtimes\mathbb{R}^{2}$.to the midterms.

The exercise was not purely symbolic, however. After Russian hackers penetrated the Democratic Congressional Campaign Committee in 2016 and posted sensitive internal campaign documents online, some of the stolen information was later amplified in Republican ads.

Meanwhile, President Donald Trump has not expressed remorse at encouraging Russia to hack into the emails of his 2016 rival, Hillary Clinton, nor has he recanted his praise for WikiLeaks , which released private emails from Clinton's campaign manager John Podesta in an effort to damage her campaign.

With congressional majorities at stake in 2018, US intelligence officials have warned of ongoing efforts by Russia to influence the midterm elections, adding urgency to the question of how campaign committees would treat hacked information.

In the latest version of the bipartisan House campaign pledge,


made this offense less common, it still may be charged as a serious felony offense under Illinois law.

Check Floating: Many people routinely write checks to cover funds that are anticipated but have not yet become available in one’s bank account. Although this may be a necessary financial measure to survive between paychecks, it may result in a felony charge and possible conviction in Illinois.

The penalties associated with check fraud increase significantly with the amount of funds allegedly obtained through the passing of a bad check. A general overview of the penalties are provided in the chart below:

Embezzlement involves fraudulently taking the funds or assets of another person or financial institution when a relationship of trust exists between the accused and the individual or entity that owns the moneyor property. This felony offense may include a range of factual situations and dollar values that affect the seriousness of the penalties. Chicago embezzlement criminal offenses may cover the spectrum from an employee in a retail store stealing merchandise from an employer to an accountant distorting or “cooking” a company’s financial books to divert funds from the company.

These are only a few examples of white-collar offenses and financial institution fraud that may carry severe consequences, which include jail or state prison time, a felony conviction on one’s criminal record, substantial fines and other penalties. The impact of a conviction for fraud-related crimes will have lasting impact beyond the formal sentence that may include consequences involving immigration status, employment, educational opportunities, housing options and loss of certain Constitutional rights.

Experienced


@berger1; @berger] to define a quantum theory and extract physics from the model were followed by more detailed analysis [@guillermo-gowdy; @husain-smolin]. Considerable progress has recently been achieved in defining a complete quantization of the (sub-)model with linear polarization [@pierri].

The quantization proposed in [@pierri] is based on the fact that the polarized model can be treated as $2+1$ gravity coupled to an axially symmetric, massless scalar field, defined in a manifold whose topology is $T^2 \times \R^+$. More precisely, once the system is (partially) gauge fixed and a choice of internal time is made, the spacetimes are characterized (modulo a remaining global constraint) by a “point particle" degree of freedom and a free scalar field $\phi$ propagating in a fictitious two-dimensional expanding torus. Thus, the problem of quantization ofthe local gravitational degrees of freedom reduces to a quantum theory of the scalar field in the fictitious background. The quantum Gowdy $T^{3}$ model is defined by using a representation for $\phi$ on a fiducial Fock space, where the remaining constraint is imposed to get the physical Hilbert space.

Despite this progress, the quantization put forward in [@pierri] has a serious drawback: the dynamics cannot be implemented as a unitary transformation, neither on the kinematical [@ccq-t3] nor in the physical [@torre-prd] Hilbert space. Even though the dynamics can be approximated as much as desired by means of unitary transformations [@jg], the model is still lacking a unitary operator that represents the genuine time evolution. The failure of unitarity is, in the best of cases [@pe], a non-trivial complication that


Klein-Gordon field. Endowing the space $\tilde{S}$ ($\tilde{\Omega}$ being its symplectic form) with the “natural" $\tilde{\Omega}$-compatible complex structure $\tilde{J}$ [@pierri]: \[pierris-cs\] (|[f]{}\_[n]{})=i|[f]{}\_[n]{}, (|[f]{}\^[\*]{}\_[n]{})=-i|[f]{}\^[\*]{}\_[n]{} , where $\bar{f}_{n}(t):=f_{n}(t,\theta)\exp[-in\theta]$, one can construct the “one-particle" Hilbert space ${\tilde{\cal{H}}}$ and, from it, the symmetric Fock space ${\cal{F}}(\tilde{\cal{H}})$ on which the formal field operator is written in terms of creation and annihilation operators \[corresponding to the positive and negative frequency decomposition defined by the complex structure (\[pierris-cs\])\]. However, the Bogoliubov transformation that implements the dynamics in the quantum theory –by relating at different times either states in $\tilde{\cal{H}}$ [@ccq-t3] (Schrödinger picture) or creation and annihilation operators [@torre-prd] (Heisenberg picture)– turns out not to be square summable in its antilinear part. As a consequence, the evolution dictated by the Hamiltonian (\[reduced-ham\]) fails to be unitarily implementable]{}. A comparison with (\[scalarf-ref-to\]) shows that we could have obtained this field operator by naively promoting the constants of motion $\{b_{n}(t_{0}),b_{n}^{*}(t_{0})\}$ in the solution to annihilation and creation operators $\{\hat{b}_{n}(t_{0})=\hat{b}_{n},\hat{b}_{n}^{\dagger}(t_{0})=
\hat{b}^{\dagger}_{n}\}$. This can be understood as the Schrödinger picture.

In the Heisenberg picture, time evolution is provided by the Bogoliubov transformation (\[b-evol\]). Namely, by calling $\hat{b}^{(H)}_{n}(t_{0}):=\hat{b}_{n}$, the relation between the annihilation and creation operators at different times $t_0$ and $t$ is \^[(H)]{}\_[n]{}(t) = \_[n]{}(t,t\_[0]{})\^[(H)]{}\_[n]{}(t\_[0]{})+ \_[n]{}(t,t\_[0]{})\_[-n]{}\^[(H)]{}(t\_[0]{}) . Thus, in this picture we get (t;)=\_[n]{}N\_[n]{}, where $N_{n}=1/\sqrt{|n|}$, except for $N_{0}=1$.

Time evolution is unitarily implementable on the (kinematical) Fock space ${\cal{F}}({\cal{H}})$ if and only if the sequence $\{\beta_{n}\}$ is square summable [@shale]. Since $\beta_{n}=\beta_{-n}$, it suffices to analyze the sequence $\{\beta_{k}\}$ with $k\in \N$. From the large-argument asymptotic expansions of the Hankel


the patients reported having been to the emergency room for asthma, and nearly one third of the patients reported having been hospitalized for asthma at some point in their life.^(^ [@B19] ^)^

In addition to the clinical, functional, and psychological consequences that asthma attacks and hospitalizations have on subjects with asthma, there is the increase in the use of health resources and, consequently, in the costs of the disease. A recent study has demonstrated that subjects with uncontrolled asthma use more health resources than do those with controlled asthma.^(^ [@B20] ^)^ In the present study, school absenteeism was higher among the patients with uncontrolled or partially controlled asthma (36.3% and 46.7%, respectively) than among those with controlled asthma (16.2%); however, these values are lower than that found in theis	 for	 a	 fixed

period	not	to	exceed	2	years.”		19-A	M.R.S.	§	4007(2).		At	the	expiration	of	that

two-year	period,	“the	court	may	extend	an	order,	upon	motion	of	the	plaintiff,

for	such	additional	time	as	it	determines	necessary	to	protect	the	plaintiff	.	.	.

from	abuse.”		Id.;	see	Gehrke	v.	Gehrke,	2015	ME	58,	¶	17,	115	A.3d	1252.		In

relevant	 part,	 “abuse”	 is	 defined	 to	 include,	 as	 between	 family	 or	 household

members	such	as	former	spouses,	“[a]ttempting	to	place	or	placing	another	in
6

fear	of	bodily	injury	through	any	course	of	conduct,	including,	but	not	limited

to,	threatening,	harassing	or	tormenting	behavior.”		19-A	M.R.S.	§	4002(1)(B)

(2015);	see	19-A	M.R.S.	§	4002(4)	(2015).

       [¶11]	 	 Ballou’s	 appeal	 challenges	 the	 court’s	 application	 of	 this	 statute

as	a	violation	of	the	First	Amendment.		We	review	the	jurisprudence	regarding

the	First	Amendment	as	it	pertains	to	harassing	or	abusive	speech,	and	then

review	the	court’s	application	of	the	protection	from	abuse	statute.

A.	    The	 First	 Amendment,	 Prior	 Restraint,	 and	 Conduct	 that	 Includes
       Harassing	or	Abusive	Speech

	      [¶12]	 	 Both	 the	 United	 States	 Constitution	 and	 the	 Maine	 Constitution

place	great	value	on	the	freedom	of	speech.		“Congress	shall	make	no	law	.	.	.

abridging	the	freedom	of	speech	.	.	.	.”		U.S.	Const.	amend.	I.		“Every	citizen	may

freely	 speak,	 write	 and	 publish	 sentiments	 on	 any	 subject,	 being	 responsible

for	the	abuse	of	this	liberty	.	.	.	.”		Me.	Const.	art.	I,	§	4.

       [¶13]	 	 We	 do	 not	 question	 the	 importance	 of	 this	 right.	 	 “Freedom	 of

speech	.	.	.	,	which	[is]	protected	by	the	First	Amendment	from	infringement	by

Congress,	[is]	among	the	fundamental	personal	rights	and	liberties	which	are

protected	 by	 the	 Fourteenth	 Amendment	 from	 invasion	 by	 state	 action.”


                                                                                9

First	Amendment.		Cropley,	544	A.2d	at	304-05;	see	also	Thorne	v.	Bailey,	846

F.2d	241,	243	(4th	Cir.	1988)	(“‘Harassment	is	not	communication,	although	it

may	 take	 the	 form	 of	 speech.’”	 (quoting	 with	 approval	 State	 v.	 Thorne,	 333

S.E.2d	817,	819	(W.	Va.	1985))).6		It	is	the	fact-finder	who	properly	determines

whether	a	true	threat	or	harassment	has	occurred.		See	Hotham,	307	A.2d	at

187.

    Shyu et al. [@b34]; Lee et al. [@b14]; Schneider et al. [@b33]; Kawada et al. [@b13]).

To date, no study has used G-CSF to compare its effects on the musculoskeletal and neural microenvironment and recovery of motor function after peripheral nerve injury in MDX mice. Thus, we used sciatic nerve axotomy, which induces muscle degeneration along the muscle fibers due to the acute effects of the peripheral nerve injury, followed by treatment with G-CSF. We also used G-CSF to analyze its effects on the neural microenvironment and functional recovery after sciatic nerve crush. This type of axonal injury is followed by Wallerian degeneration (WD) distal to the lesion site (Waller [@b43]). Cytokines---the mediator molecules of inflammation---are produced during WD and regulate molecular and cellular events including the recruitment and


the Laboratory of Nerve Regeneration, Department Structural and Functional Biology/Unicamp, Brazil. The study was approved by the Institutional Committee for Ethics in Animal Experimentation (CEEA/IB/UNICAMP, proc. 1776-1) and the experiments were performed in accordance with the guidelines of the Brazilian College for Animal Experimentation (CONCEA).

The experimental groups are presented in Table [1](#tbl1){ref-type="table"} and Table [2](#tbl2){ref-type="table"}. In the drug-treated groups, the mice were pretreated with 200 mg/kg/day G-CSF subcutaneously for 7 days prior to and 10 days after the sciatic nerve crushing. In the placebo groups, the mice were pretreated with 200 *μ*L of 5% sucrose. From the 11th to the 21st day, G-CSF was administered on alternate days.

######

Groups and techniques used in mice subjected to sciatic nerve crushing

         nerves were frozen and embedded in Tissue-Tek (Miles Inc., Torrance, CA) and frozen in liquid nitrogen at −24°C for cryostat longitudinal sectioning (12 *μ*m). Primary mouse anti-neurofilament (1:100; Chemicon, Billerica, MA), goat anti-p75^NTR^ (1:200; Santa Cruz, Dallas, TX), and anti-sera were used. The anti-sera were diluted in BSA and Triton X-100 in 0.01 mol/L PBS. The sections were incubated overnight at 4°C in a moist chamber. After rinsing in 0.01 mol/L PBS, the sections were incubated with Cy3- or Cy2-labeled secondary anti-sera (1:250; Jackson Immunoresearch, West Grove, PA) for 45 min in a moist chamber at room temperature. The sections were then rinsed in PBS, mounted in a mixture of glycerol/PBS (3:1), and observed using a Nikon TS100 microscope that was equipped with a digital camera (Nikon, Tokyo,


found between 2.5 and 7.5 *μ*m, representing 87.76% of the axons, and the remaining axons (12.24%) were distributed to other classes. In C57BL/10 contralateral + G-CSF group, axon diameters ranged from 1.13 to 13.65 *μ*m. Most diameters were between 2.5 and 7.5 *μ*m, corresponding to 92.91% of total axonal fibers. The remaining axons (7.09%) were distributed to other classes. The axon diameters in the MDX ipsilateral + G-CSF ranged from 1.10 to 10.07 *μ*m, with the largest percentage of axons in the range 2.5--4.5 *μ*m, corresponding to 76.29% of the total axons. The remaining 23.71% of axons were distributed to other classes. In C57BL/10 ipsilateral + G-CSF group, diameters of axons ranged from 1.08 to 29.28 *μ*m, with most found between 2.5 and 4.5 *μ*m, corresponding to 84.9%based on the presence of centrally positioned nuclei. *N* = 5 for all experimental groups. Scale bar = 50 *μ*m." The quantification was performed over the entire nerve area shown in each photo. For I and J, values are the mean ± SEM.](brb30004-0738-f6){#fig06}

Seven days after sciatic nerve axotomy, soleus muscle fiber was quantified. During ipsilateral analysis, we observed a protective effect of the drug on muscle fibers, with MDX + G-CSF group showing that 62% of fibers were unaffected by degeneration. In the MDX untreated group, we observed that 51% of the fibers were not affected by degeneration (Fig. [6](#fig06){ref-type="fig"}I). Thus, 38% of the fibers were regenerated in the MDX + G-CSF group, and 49% were regenerated in the MDX untreated group. In C57BL/10 mice, no differences between


traveling 56 mph on a street with a posted speed limit of 35 mph. The officer pulled into traffic behind Moody and stopped him for speeding. The officer asked where Moody was coming from, and he replied that he had been at a bar where he consumed five drinks. While talking with Moody, the officer noticed that his eyes were bloodshot and watery, that his speech was slow, and that he smelled of alcohol. The officer then asked Moody to step out of the car and administered several field sobriety tests. According to the officer, the horizontal gaze nystagmus test revealed four out of six clues, the walk and turn test revealed five out of eight clues, and the one leg stand test showed four out of fourthat has been developed as an alternative telephony technology to the conventional telephony service (e.g. PSTN). VoIP takes advantage of high speed Internet data switched networks, and is able to provide low cost telephony services to end users. VoIP technology emulates a phone call, but instead of using a circuit based system such as the telephone network, utilizes packetized data transmission techniques most notably implemented in the Internet.
Voice Over IP is not a single technology, but rather four distinctive applications targeted at distinct market segments in either static, portable, or mobile environments. A first application is the use of VoIP technology with cable and digital subscriber line (DSL), often deployed in static configurations in which the end user stays at a fixed location and uses the standard North


        1. The VoIP device is physically connected to a static data cable at a “home” address.        2. The VoIP device is physically connected to a data cable at a location different than its “home” address. For instance, a laptop computer device utilized away from home as a VoIP communication device would be a VoIP ‘visitor’ device as described by this scenario.        3. The VoIP device is wirelesses, physically disconnected from any data cable. In this situation, the VoIP device connects to the VoIP network via cellular or WiFi technology.
A VoIP gateway is a gateway that bridges a VoIPwhich shows a conventional architecture for providing 911 service to a VoIP device.
In particular, as shown in FIG. 12, a conventional architecture routes VoIP 911 calls to a designated PSAP. However, such architecture fails to provide “enhanced” service for VoIP devices.
In particular, Option 1 in FIG. 12 shows an IP device 250 utilizing VoIP protocols for voice communications dials 9-1-1. The VoIP device 250 is serviced by a VoIP switch 220 in the VoIP service provider's network. The VoIP switch 220 communicates with a Message Servicing Center (MSC) 230. Using a database that relates the devices callback number or IP address to the owner's address, the MSC 230 can determine which PSAP has jurisdiction for that address. The MSC 230 then communicates back to the VoIP switch 220


a 10-digit telephone number for that PSAP. The VoIP Switch 220 then converts the IP call to TDM and routes the call to the designated PSAP using the provided 10-digit number.
A primary challenge results from the fact that the E911 network is not directly accessible via the Public Switched Telephone Network (PSTN); Rather, all enhanced 911 calls must be routed via dedicated local voice trunks to a selective router that in turn routes the call to the PSAP. Calls that do arrive at the PSAP arrive without callback number or location information. Provision of location information to the PSAP via the PSTN also circumvents specific PSAP hardware (e.g., CAD, GIS) designed to facilitate dispatching of responders and tracking the location of the mobile caller.
There is a need forunderstand that the Tea Party is nothing more than the rebirth of the original principles set forth by the Republican Party. So, you and your cronies need to stop calling them the 'Tea Party' people and start recognizing them as who they really are ... Constitutional, principled patriots!

But, sad to say, I don't believe you have it in you any longer. You need to resign and leave Congress this year. And, take the 28 Republicans who voted for raising the debt ceiling, with no restrictions, along with you. And, while you're at it, write a letter to Reince Priebus of the RNC and tell him to go away as well! Remember when Obama said 'if they bring a knife to the fight, we'll bring a gun'? Well, you


guys have brought the knife. The Tea Party has the guns! Yet, you down them. Amazingly stupid!

I'm almost certain you won't take this advice because, quite frankly, you actually think you're doing a good job! Talk about lying to yourself and becoming totally blind to reality ... you've managed to accomplish it.

Many of us who were proud that you became Speaker of The House have become quite disenchanted with your lack of leadership, attack on the Tea Party, and your surrenders to our empty suit president. Have some courage and do the right thing for your country. Pledge your life, your fortune, and your sacred honor to the continued success of the greatest nation on the face of this earth ... EVER! Otherwise, it's time for you tothat the
lesser practice could not be considered part of their
culture. That may not have been your intent, but
that's how it came across to a simple man.
Concerning your comments about the relative
smallness of our minds, let me remind you that you
were the first to accuse me of small thinking.
On this blog, you have accused me of small thinking
and a tendency to down people (a bit of urban
slang from an old man ?) so what is it Bob, do
I reply in kind or just turn the other cheek and
get swatted on both sides ???

Grouch,
I don't have to look up anything on culture. It's an accumulation of all traits combined that form the opinions of virtually all members of a society. For example, the importance of knowing a foreign language. ...


Texas ranchers about ... More ›

Grouch,
Wow. Your whole cultural lesson was not to arm wrestle a real working man for a round of drinks? You could have learned that in Buck's Saloon just up the road from me. I guess that would make Texas ranchers about the same as German farmers. So, your deduction, I assume, would be that there is no difference in American and German culture. Talk about small thinking.

Tivoli Gardens in Copenhagen established August 15,
1843 is a large amusement park. Trier contains the
largest Roman city gate north of the Alps. I think it's
is called the black gate, not sure about the Latin
name but I ... More ›

Tivoli Gardens in Copenhagen established August 15,
1843 is a large amusement park. Trier contains the
largest Roman city gate northI have no faith left in anyone that represents citizens and that includes our other Senator. If a Represenative or a Senator won't stand up and call obama or anyone else a 'liar' when they are lying, then they need to sell their Washington house and move back home. A word about Ran Paul: he's just an acorn from the old oak tree known as Ron Paul. I don't care what you are hearing from him, he's just a strange and radical politician that is not realistic in what he'd like to accompish. I'm afraid that nothing short of disbanding the government and starting over will accomplish much.

Hey Bob, You could have just use the term
"realistic" instead of being so verbose. There
I go again, being negative. :-) It


pledge your, your fortune and
your sacred honor to uphold the constitution
of our great nation. It is only the adherence
to this sacred document ... More ›

Dear John,
As a constitutionally principled patriot, I
insist that you pledge your, your fortune and
your sacred honor to uphold the constitution
of our great nation. It is only the adherence
to this sacred document that our nation can
prosper and pass this legacy onto our children.
I also insist that you protect the entitlements
promised, albeit unconstitutional, to the American
citizens.
Signed
Constitutional Principle Patriot
aka Tea Party Person with a gun.

Senior Citizen....Congratulation of your good
health. I am also blessed with the good sense
to pursue a healthy lifestyle. With the exception
of my payments, I also paid medicare taxes for
a portion of my eligibility period, ... More ›

Senior Citizen....Congratulation of your good
health. I am also1. Field of the Invention
The present invention relates to an exposure control apparatus of a camera having a plurality of exposure modes.
2. Description of Related Art
In a conventional camera having a plurality of exposure modes, a photographer can select a desired exposure mode by actuating an associated switch or button etc.
In a recent camera having modes other khan the exposure modes, such as a continuous shot mode, etc., mode selection is effected by activating a plurality of switches in combination.
However, ordinary photographers do not often use all of the various exposure modes, but rather use only a few specific exposure modes. Therefore, for the ordinary photographer, the need to activate several switches in combination to effect a mode selection is troublesome and complicated. A photographer is therefore prevented


fruits (below the sepals) still attached to the plants. Control fruits were injected with distilled water. (A, E, I, M, Q) Untreated MG fruits. (B, F, J, N and R) Untreated fruits at 8 d. (C, G, L, P, T) Eight days after NDGA treatment; (D, H, K, O, S) 8 d after ABA treatment. (U) Breaker day. (V) ABA contents before and after ABA treatment in the control and treated fruit. \**P*\<0.05; \*\**P*\<0.01, *t*-test.](erz396f0005){#F5}

Effect of SlPYL9 on fruit ripening and quality {#s20}
----------------------------------------------

The obvious phenotypic change in the transgenic lines was related to fruit ripening. Fruits were therefore analysed for physiological and biochemical parameters ([Fig. 6](#F6){ref-type="fig"}; [Supplementary Fig. S6](#sup1){ref-type="supplementary-material"}). As shown in [Fig. 6A](#F6){ref-type="fig"}, fruit ripening was significantly accelerated by 6--7 d in both *SlPYL9*-OE lines compared withof only 10 *SlPYL* genes in breaker fruit, the peak point during fruit development. This result suggests that the number of PYL family receptors is less than in Arabidopsis and other tomato varieties. Similarly, in a recent paper, *Brachypodium* was also found to have only a small number of ABA receptors ([@CIT0033]). It is generally believed that Arabidopsis shows functional redundancy in ABA receptors, with the complex *pyr1--pyl1--pyl2--pyl4* quadruple mutant leading to broad spectrum ABA hyposensitivity ([@CIT0029]; [@CIT0028]). Thus, this suggests that single receptor loss-of-function would result in a very weak ABA-insensitive phenotype. However, genetic and biochemical analyses of ABA signaling components in tomato and Arabidopsis revealed that despite high conservation, the extent of receptor redundancy differs between the two species. Herein, this raises the question as to


the petal held firmly to the top of the young fruit, resulting in a gourd-shaped fruit and thereby affecting the fruit shape index. These results suggest that petal abscission is determined by a dynamic balance of hormones (GA, IAA, and ABA), modulated by SlPYL9-mediated ABA signaling during anthesis. Furthermore, they also suggest that the interaction between genes is characterized by a more variable profile related to flower/fruit tissue-specific modulation, warranting further characterization.

In conclusion, the results of this study suggest that SlPYL9 is an ABA receptor that positively regulates ABA signaling and fruit ripening. In line with this, *SlPYL9*-OE/RNAi plants showed typical ABA hypersensitive/hyposensitive phenotypes. Moreover, *SlPYL9*-OE significantly accelerated fruit ripening by 5--7 d, while *SlPYL9-*RNAi delayed fruit ripening, enhanced mesocarp thickness, and hindered petal abscission. These results suggestS9. Effects of dehydration stress on WT and transgenic fruit.

Table S1. Specific primers used for gene amplification for *SlPYL9*-OE/RNAi plasmid construction.

Table S2. Specific primer sequences used for real-time quantitative PCR analysis.

Table S3. Quantitative PCR primers used to analyse the expression of ripening-related marker genes in *SlPYL9*-OE and RNAi lines.

Table S4. Specific primer sequences used for subcellular localization assay of SlPYL9.

Table S5. Specific primer sequences used for SlPYL9 and SlPP2Cs in a bimolecular fluorescence complementation (BiFC) assay.

Table S6. Specific primers used for *SlPYL9* expression *in situ* hybridization.

######

Click here for additional data file.

Data deposition {#s29}
===============

The following data are available at Dryad Data Repository ([https://doi.org/10.5061/dryad.5q449h5](10.5061/dryad.5q449h5)[@CIT0016]).

Dataset 1. The expression of fruit ripening-related genes in fruits at the breaker stage detected by RNA-Seq.

Dataset 2. Genes expressed differentially in the WT and transgenic


was a huge community. Thousands of people contributing to React Native source code, multiple libraries and components, lots of tutorials and sample apps. You have got to admit, it’s quite impressive.

Javascript used to scare me the most. I only had few occasions to write JS code. It was a long time ago and for the type and object-oriented developer, like myself, that was something understandable. However, JS has changed a lot since then. Obviously it still is a dynamically typed language, but it looks more object-oriented now. It also has a fantastic solution for asynchronous code: asyncawait, the one I have badly missed from C#.

I needed only a few minutes to start playing with React Native. After reading a tutorial and experiments, I decided to build the proofusers list and see other users details and their remote status. Plus, the app didn’t look too bad. React Native uses Flexbox to build layout for various screen sizes. It is user-friendly and allows many customizations. I can honestly say that creating iOS views has never been simpler.

What next?

I will never abandon native iOS development. I enjoy working with Swift and I’m really happy that I could discover pros and cons of React Native on my own. It has given me out-of-the-box perspective on the whole mobile development and it has shown that iOS has some limitations too, yet we are used to them. The most valuable thing I have found in React Native is the power of fully reactive programming.

I still think that the experiment hasn’t given


    frame.addWindowListener (new WL (frame));

                JLabel lab = new JLabel ("just some information");

                frame.setPreferredSize (new Dimension (400, 300));
                frame.setResizable (false);
                frame.add (lab);
                frame.pack ();
                frame.setVisible (true);
         of all your settees, , cupboards, sinks, lorry tyres (can cost more as expensive to dispose of), cuttings or piles of topsoil / dirt safely at a registered dump from anywhere in Essex CO5.


video interview with Davis. Adjacent to the exhibit is a Vietnam firebase display containing a 105mm howitzer like the one Davis crewed. The exhibit was officially unveiled by Governor Mike Pence on May 28, 2013.

Bricks of Remembrance Program

The Indiana War Memorials Foundation has launched its "Bricks of Remembrance" program to memorialize veterans. Each brick will be engraved with the name, rank, branch and dates of service of an individual veteran, and placed at Monument Circle, the very heart of the State of Indiana and its capital city of Indianapolis. These dedicated bricks will encircle the Soldiers & Sailors Monument, ensuring that our heroes will not be forgotten by future generations. You can contribute to the placement of as many bricks as you wish for $100 tax-deductible charitable donationwho may benefit from the procedure and also an increased emphasis in training new surgeons to be well versed in this technique.^[@bibr7-2325967118755048]^

Hip arthroscopic surgery is a challenging procedure because of the spatial constraints of the joint and its surrounding capsule, demanding a high level of technical proficiency.^[@bibr24-2325967118755048],[@bibr25-2325967118755048]^ Few studies have investigated the relationship between surgeon experience and patient outcomes for newly trained surgeons because data are rarely collected from their first surgery. Two studies of FAI demonstrated that complication rates in hip arthroscopic surgery decreased with experience^[@bibr31-2325967118755048]^ and that lower complication rates occurred with a newly trained surgeon under supervision compared with a newly trained unsupervised surgeon, suggesting a need for supervision early in a surgeon's career.^[@bibr9-2325967118755048]^ However, a retrospective study of a single surgeon's experience found that


there was no significant change in the incidence of complications based on surgeon experience.^[@bibr36-2325967118755048]^ Because overall complication rates of hip arthroscopic surgery are low,^[@bibr20-2325967118755048]^ measuring PROs may provide a better understanding of a patient's pain and functional status postoperatively.^[@bibr34-2325967118755048]^ Konan et al^[@bibr19-2325967118755048]^ assessed a single surgeon's experience by analyzing Non-Arthritic Hip Score (NAHS), operation time, and complication rate and estimated that there was a learning curve of approximately 30 cases, as there was an increase in postoperative NAHS values between the early and late cases. An additional study by Lee et al^[@bibr22-2325967118755048]^ investigated a surgeon's experience using the modified Harris Hip Score (mHHS) and concluded that the surgeon required approximately 20 cases to achieve satisfactory mHHS value improvements.

Because of the small number of studies using PRO surveys toinvestigate surgeon experience and patient outcomes, it is unclear whether a newly trained surgeon's early hip arthroscopic surgery cases will have different outcomes than the surgeon's later cases. We aimed to conduct a prospective analysis of a sports medicine fellowship--trained surgeon's first independently performed hip arthroscopic surgery cases in practice to evaluate the relationship between surgeon experience and patient outcomes for the arthroscopic treatment of FAI. The primary outcomes measured in this study were PRO scores, and secondary outcomes included operation times and complication rates. We hypothesized that the early group of patients would have significantly worse PRO scores and an increased number of complications as well as longer procedure and traction times compared with the later group of patients.

Methods {#section1-2325967118755048}
=======

Patient Selection and Data Collection {#section2-2325967118755048}
-------------------------------------

Patients undergoing hip


arthroscopic surgery for symptomatic FAI by a single sports medicine fellowship--trained orthopaedic surgeon (A.L.Z.) were prospectively enrolled. The surgeon completed fellowship training at the same institution before his appointment as faculty, but hip arthroscopic surgery training was not emphasized during his fellowship, as there was not a previous faculty member who specialized in sports injuries of the hip. All patients provided consent before enrollment, and the study protocol was reviewed and approved by the institutional review board. Inclusion criteria consisted of patients diagnosed with symptomatic pincer, cam, or mixed-type FAI with failure of conservative management and physical therapy. Although all except 1 patient also had labral abnormalities, this finding was not a specific inclusion criterion. Intra-articular injections were used for diagnostic and therapeutic purposes before arthroscopic surgery, butShort Form Health Survey; VAS, visual analog scale.

*^b^*Student unpaired-samples *t* test.

Discussion {#section12-2325967118755048}
==========

Hip arthroscopic surgery is technically challenging but offers advantages compared with open surgery for FAI because of its minimally invasive nature.^[@bibr21-2325967118755048],[@bibr30-2325967118755048]^ As previous studies have noted a steep learning curve for hip arthroscopic surgery,^[@bibr9-2325967118755048],[@bibr19-2325967118755048],[@bibr22-2325967118755048],[@bibr31-2325967118755048]^ the purpose of this study was to prospectively evaluate the relationship between surgeon experience and patient outcomes for hip arthroscopic surgery in the setting of FAI. We found that although the total procedure time and traction time may decrease after a surgeon's first 30 hip arthroscopic surgery cases for FAI and labral tears, PROs can improve regardless of surgeon experience.

The significantly decreased total procedure time and traction time in the late group compared with the early group indicated that accrued surgeon experience after


mHHS^[@bibr22-2325967118755048]^ as the surgeon gained experience, which the studies attributed to the learning curve. In our study, the late group demonstrated a similar change in PRO scores compared with the early group. Therefore, we cannot conclude that the late group had superior PRO scores. Our study used the mean change in preoperative and postoperative scores to measure improvement, which differs from many studies that compared only postoperative PRO scores.^[@bibr10-2325967118755048],[@bibr12-2325967118755048],[@bibr19-2325967118755048],[@bibr22-2325967118755048]^ Evaluating the mean change in values may be a better way of illustrating improvement because if the patient started at a lower preoperative score, this method captures his or her progress regardless of the final postoperative score. Additionally, our study benefited from the use of multiple PRO surveys instead of one and only evaluated patients treated for FAI andtime may decrease after a surgeon's first 30 hip arthroscopic surgery cases for FAI and labral tears, but patient outcomes can improve in a similar manner regardless of surgeon experience in the early part of his or her career.

One or more of the authors has declared the following potential conflict of interest or source of funding: S.E.F. was the recipient of the 2017 Heiman Fellowship Summer Grant. A.L.Z. was the recipient of the 2016 AOSSM Young Investigator Grant and is a consultant for Stryker.

Ethical approval for this study was obtained from the University of California, San Francisco Human Research Protection Program (approval No. 14-14742).


gorilla in a tuxedo?" "Okay, Molly, to find your missed connection, let's start by retracing your day." "Well, I got up and went to Ray's coffee house." "Oh, I go there, too." "Okay, so you woke up and got your fancy, bohemian" ""better than everyone else" coffee." "What next?" "I went to the central park reservoir to read the paper." " [ Chuckles ] I go there all the time." " You run there?" "[ Laughs ] That's very sweet of you, but no." "[ Clears throat ]" "I like to go there and watch the runners gasping for air as I enjoy my coffee." "Me too." "It makes me feel like I'm working out without all that stupid moving." "Exactly." "Well, I'm sure you both will endnow?" "[ Deep voice ] I always assume everyone's a sniper." "[ Laughs ]" " [ Normal voice ] Um, do you want anything?" " I'm good." "Okay." "I'm gonna check in with Tyler and grab myself a vanilla latte with an add shot." "Hey, that's whatI always get." "Oh, look at that." "We're like twinsies." "If one of us was really scruffy." "Oh, come on." "You're not thatscruffy." "Says the scruffy pot to the kettle." "Pretty cute kettle, though." "Uh, I'm gonna go check in with the boss." "[ Clears throat ]" "[ Cellphone rings ]" "Go for "T-Dog."" "Milo:" "Hey, T-Dog, uh, we're all set here." "How goes it on your end?" "Locked and loaded, chief." "I got the southern and western entrances covered." "The manager's


tomorrow morning." "Should I order two?"" ""Signed, cute kettle."" "So, you liked her?" "There was a connection." "[ Voice breaking ] Your grandkids will love that story." "Are you crying?" "How are you not?"Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis.
Human T-cell leukemia virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) represents one of the most devastating diseases associated with HTLV-I infection. Despite the delineation of clinical features associated with this neurologic disease, more progress needs to be made with respect to understanding the molecular mechanisms relating to the genesis of HAM/TSP. Several factors have been hypothesized to contribute to whether an HTLV-I-infected individual remains asymptomatic, develops adult T-cell leukemia (ATL), or progresses to HAM/TSP. Among the most intriguing of these factors is the immune response mounted by the host against HTLV-I. Several cell populations are crucial with respect to generating an efficient immune response against the virus. This includes CD4(+)


University found that white women married to black men suffer the greatest psychological distress and social stigma. Next are Native American men, who actually out-marry the most. Latino and Asian men and women who are married to African-Americans reported the next highest levels of anguish. Interestingly, and despite mediated depictions to the contrary, African-American men and Asian women marrying whites experience the least distress when engaged in interracial relationships.

The issue of psychological impact suggests that although interracial relationships are on the rise, they are neither gaining equally nor is the increase a sign of equal acceptance in a larger social sense. In fact, according to census data, interracial couples have a slightly higher divorce rate than same-race couples. These facts add a layer of meaning that needs toeducation for the next generation of physicians and other health care professionals. They are the setting of the biomedical research that has led to many of the diagnostic and therapeutic tools used in modern medicine. These institutions also provide highly specialized services (such as transplants and burn care) not generally available at other institutions in the health care system. Lastly, these hospitals are an important part of the social safety net in our country; although AMCs represent only approximately 5% of the acute care hospitals in the United States, they provide more than 40% of the care to the uninsured (because of their size, location, and humanitarian spirit).1

As national health care reform moves forward, new and changing policies must continue to support and advance the essential missions of