P-chan is cruel and heartless." "Mr. Hoshi, don't we have another option besides eating her?" "Well..." "Okay, then." "Many of you say we shouldn't eat her, but those of you saying so, what do you propose we do with her in the future?" "Okay, Hiroki." "We should consider keeping her here." "When we first started this, didn't we decide to take full responsibility until the end?" "I don't think we should force her on someone else." "But taking full responsibility means that we should take care of her until she dies naturally." "Okay, Mizuki." "But even if she stays here, we'll all graduate." "Then P-chan will be all alone." "What then?" "But even so, eating her is heartless." "We have to decide the end." "What do you meanhandle her." "If P-chan were served in front of me," "I'd eat her." "But it's not like I'll starve if I don't eat P-chan." "Then you'll never eat pork again?" "Sure." "Eating only vegetables isn't enough." "Why are you laughing?" "Why are you laughing?" "Be serious, everybody." "P-chan's going to die someday." "So it's okay to kill her now?" "That's not what I meant" "Pigs usually become meat in 6 months, so she's had a full life." "So it's okay to kill her?" "So it's okay to eat her?" "How can you say that?" "Killing and eating aren't the same." "What's the difference?" "Killing is just robbing life." "Eating means we inherit the animal's life." "P-chan's our classmate." "How can you talk about eating her?" "It's hard, but


two equal pieces. Take the first piece and flatten it with a rolling pin on your counter into a square or a rectangle. Now, add half of the mixture from step 5 on top of the dough, and roll this up into a log. Now, do this again with the remaining ingredients. The yield is two rolls of sausage bread.

Place both of these rolls onto your baking sheet lined with parchment paper. Brush both logs with the two remaining eggs after beating the eggs.

Now, it’s oven time! Place the baking sheet into your preheated over and cook for about 1 hour. Start to keep an eye on things after about 45 minutes, just to make sure.

Now you’re all done and left with cheesy, meaty and delicious rolls ofmachine recipes but here’s a small sample;

A rye bread recipe for the bread machine is designed to add nutritional value to your diet. Rye is a European cereal that has the same nutritional value as wheat. Rye is mainly known for the number of vitamins it contains. Rye has vitamin D, vitamin E, zinc, niacin, iron, and fibre which is great for you and the entire family. Those who are fond of conventional sliced white bread should try this variety. Many would say it’s much tastier than regular white bread and there’s only a fraction of the sugar and calorie content.

A sourdough bread machine recipe is another unique variety that many people are fond of. There are lots of nutrients which are present in sourdough, which is partly


moment, a cushiony denouement -- by gum, closure. If this stands in counterpoint to Pynchon’s most acclaimed work, perhaps we should pay heed to the novel’s title: “Inherent Vice” refers to a hidden defect that undermines a property’s worth, a marine-legal term for a Shakespearean flaw. It could refer to Los Angeles; it could refer to the 1960s. Or it could refer to the author’s work itself: With Pynchon’s brilliance comes readability.

Kellogg is the lead blogger for Jacket Copy, The Times’ book blog.be something unique."

Argentina will face Iceland (June 16), Croatia (June 21) and Nigeria (June 26) in Group D at the World Cup, starting next month.

The two-time world champions – who last won the showpiece event in 1986 – scraped into the tournament thanks to Messi's magic.

And Messi conceded Argentina are below the likes of Brazil, Spain and reigning champions Germany.

"I have great faith in this group, we are working very well, we have players with a lot of capacity and experience," he said.

"But we do not have to throw the message of 'we are going to be the world champion because we are the best', because the reality is that it is not like that."

On Group D, Messi added: "Iceland are a team that showed in the last


the top of said ditch 40.4 feet to a grader blade in the center of an east-
       west ditch; thence North 85 Degrees 36 Minutes West along the center of the
       east-west ditch 109.5 feet to a grader blade 34.5 feet east of the centerline of
       the highway; thence North 104.5 feet to the point of beginning, being a part of
       Block 8, McInnis First Addition according to the official map of Inverness,
       Mississippi, drawn by L.E. Claiborne, April 7, 1953.

(Emphasis added). On September 10, 2012, the foreclosure sale was held, and the property

was sold to Green Tree.able to move in with her boyfriend; thus, she

would not suffer irreparable injury, loss, or damage. The chancery court held Green Tree’s

and Robison’s motions for dismissal in abeyance. Then, on May 28, 2013, the chancery

                                              4
court heard arguments on the merits. After hearing the evidence, including two expert

witnesses’ testimonies as to what effect, if any, the omission of the word “line” would make

in the property description, the chancery court found in favor of Green Tree and Robison, and

it dismissed Hall and Thomas’s complaint.


criteria were life threatening diseases and severe aphasia (as it would reduce the validity of the neuropsychological assessment). Clinical and neuropsychological data were collected using standardized clinical, psychiatric, and neuropsychological assessment (see below). Of the 169 patients, 126 underwent brain MRI examination at inclusion ([@B38]) T1W 3D brain MRI images were available for 112 patients (**Figure [1](#F1){ref-type="fig"}**).

2.  ADNI -- An established classification model based on RF trained to discriminate between patients with AD (*n* = 185) and healthy controls (HC, *n* = 225) using Freesurfer (v. 5.1) measurements from T1W 3D brain MRI was also used on the PRODE dataset. The training data was obtained from the ADNI database^[1](#fn01){ref-type="fn"}^. The ADNI was launched in 2003 as a public-private partnership, led by Principal Investigator Michael W. Weiner, MD.based on age and gender (*n* = 40) and controlling for the balance in number of CS and MCI at each center of inclusion (**Figure [1](#F1){ref-type="fig"}**).

Ethics Statement
----------------

The participating patients and caregivers were given oral and written information, and they subsequently gave their written consent to participate. The PRODE study was approved by Regional Committee of Medical Research Ethics and Privacy and Data Protection Officer at Oslo University Hospital (approval number 2009/1774).

MRI
---

### MRI Acquisition

All scans were optimized and harmonized across centers based on American College of Radiology (ACR) phantom and a healthy volunteer. This study is based on T1 3D brain MRI obtained with sagittal volumetric magnetization-prepared rapid gradient echo (3D MP-RAGE) images using the ADNI T1W volume protocol ([@B31]) in six PRODE centers with 1.5T and 3T MRI


trees ([@B8]). RF selects a bootstrapped subset of all observations -- about 66% per tree and random subset of all predictors/features (here: CTH, SV) at each node of the tree. RF uses the majority vote of its trees terminal nodes to predict the class label of a new observation. Each tree casts a unit vote for the class. Thus, high numbers of decision trees are expected to increase reliability of the results. For each predictor a Gini index is estimated at each node. Overall importance of a predictor for the model is based on the summation of the decreases in the Gini index at each node ([@B8]). The remaining 33% of the data, i.e., out-of-bag (OOB) data, is used to measure the RF performance. The classification error ofbut in non-depressed elderly and based on arterial spin labeling. This study reported that perfusion in a region of interest in the posterior cingular cortex could distinguish those developing MCI from a CS group with an AUC of 66% ([@B66]).

Brain Regions Important for Prediction of MCI and Dementia Diagnosis
--------------------------------------------------------------------

The most important regions for predicting a diagnosis of MCI or dementia after 1-year follow-up were volumes of R-VD, mid-anterior CC, and R-HC, respectively.

Right ventral diencephalon was demonstrated to be the most relevant structure. The ventral diencephalon in Freesurfer includes several structures: hypothalamus with mammillary body, subthalamic, lateral geniculate, medial geniculate and red nuclei, substantia nigra and surrounding white matter. Some of these structures, i.e., substantia nigra and red nuclei, are not locate to the diencephalon but mesencephalon according to


preclinical AD, and interestingly the combination of reduced forebrain and hippocampal volumes was associated with more rapid cognitive decline. However, to the best of our knowledge the current study is the first study to assess the role of the entire ventral diencephalon in the context of neurodegeneration. There are two previous studies examining the ventral diencephalon (segmented in Freesurfer) in relation to mood disorders. The first showed that bilateral ventral diencephalon volume obtained from Freesurfer was one of three top-ranked endophenotypes of major depressive disorder in an analysis of a high-dimensional set of over 11,000 traits ([@B26]). The other study demonstrated that volume of the ventral diencephalon discriminated patients with major depressive disorder from those with bipolar depression as well as controls ([@B54]). Taken together, these findings suggestthat neurodegeneration in ventral diencephalon including the hypothalamus might be a link between depression and cognitive impairment.

After R-VD, CC (mid-anterior CC) and hippocampal (R-HC) volumes were the most relevant structures for predicting MCI-DEM. HPA-axis dysregulation is associated with elevated cortisol levels ([@B47]; [@B20]) which is hypothesized to cause reduced CC and hippocampal volumes due to neurotoxic effects ([@B4]; [@B41]). The importance of CC volume for predicting MCI-DEM suggests presence of inter-hemispheric disconnection already in the early stages of the neurodegenerative process. Previously, it has been shown that anterior, middle and posterior portions of the CC have less volume in AD compared to controls, but only the middle part was smaller in amnestic MCI compared with controls ([@B49]). Moreover, decreased volume of mid-anterior portion of CC has been linked


scans obtained from scanners with different magnetic field strengths might be considered a limitation; however, it was shown that Freesurfer output measurements are consistent between 1.5T and 3T MRI, which was confirmed in our reliability analysis. We have shown that ICC is high across the centers. We also balanced the number of participants from each center and verified the results excluding each center, in order to assess reliability of the results which were consistent.

Possible Practical Implementation
---------------------------------

Our results suggest that LLD with smaller volumes of the R-VD, mid-anterior CC, and R-HC and lower MMSE scores at inclusion have a higher probability of receiving a diagnosis of MCI or dementia the following year. These measurements can provide clinicians with novel evidence for an expected trajectory of cognitive functioning in LLDCoastal Conservation League seeks compromise on International Drive

HORRY COUNTY, SC (WMBF) - While International Drive is moving forward in the permitting process, the project still isn't ready to actually start.The South Carolina Department of Health and Environmental Control has approved the permit for International Drive, denying the Coastal Conservation League's request for review.

Even though it ultimately ended in denial, Coastal Conservation League's North Coast Office Director Nancy Cave said she's actually feeling encouraged because DHEC went into executive session to talk about the request to review. It brought up animal passageways, which the group has been pushing for to give bears in Lewis Ocean Bay Heritage Preserve a way to migrate without the risk of getting hit by cars on International Drive.

There are still steps the Coastal Conservation


League could take to oppose the construction plan.

Ride II Chairman Mike Wooten said the next step would be an appeal to the administrative law court within the next 30 days. If the court rules against the appeal then an appeal could be filed to the South Carolina Court of Appeals and, finally, an appeal to the South Carolina State Supreme Court would be the last resort. He said that entire process could take a couple of years.

However, Cave said an appeal isn't going to be the first course of action. She said she wants to reach out to Horry County and try to have a conversation about the issue.

"We don't want to stop the road," Cave said. "We would like to have a conversation with Horry County andnight, however, may actually affect any aspect of sleep. Other co-occurring sleep disorders, such as sleep apnea, REM behavior disorder, and restless legs syndrome are also very common.\[[@ref29]\]

These sleep problems are associated with a poor quality of life for the patient and the caregiver.\[[@ref27][@ref30]\] The etiology of insomnia in PD is multi-factorial. Previously, established causes include, advanced age, nocturnal motor symptoms, and psychiatric complications such as depression and hallucinations, and also medication effects, which may disrupt the sleep architecture and lead to motor fluctuations.\[[@ref3][@ref13]\]

This study showed no significant relationship between poor sleep quality and duration of disease. Previous research has indicated an association between poor sleep and duration of diseases.\[[@ref31]\] Our study demonstrated poor nocturnal sleep quality in patients with PD compared with the control group. New ways


sometimes gets angry because she does ignore her directions. Ava was the one who had a lot of ideas, but she also wanted her team to contribute with new and innovative ideas. She found out that she had to give her team more time and space to create innovative ideas, since she tends to be very quick and dominant when she is Confluence driven. She also understands that her avoiding Sequence leads her to give unclear directions.

The Covenant

Ava, especially, was very pleased to see that the whole lively conversation ran in a very constructive and respectfully way. Out of their high Precision, the team decided to write the main points of their considerations and thoughts down. Out of this document they prepared a Team Covenant on a flip-chart:

BeforeQ:

Rails - Move view's javascript code to javascript files

First let me tell you that I've searched for this and didn't manage to find any answer for my problem.
I have a lot of Javascript on my layouts/application.html.haml file:
### at the end of application.html.haml file

- if @instance_variable.condition

    :javascript
        // a lot js/jQuery code

    :javascript
        // more js code that uses #{ @instance.vars }

    - if @another_condition.using.ruby.cody

        :javascript
            // more js code that uses #{ @instance.vars }

And I'm using instance vars within this code, which means that this vars will


the Bharatiya Janta Party (BJP) in Bihar and Telangana respectively.

During the Lok Sabha election, they reported to Mr. Shah, who is the BJP president. Prime Minister Narendra Modi has asked all Cabinet Ministers to delegate more work to Ministers of State and involve them in decision-making.The disclosures herein relate generally to orthopedic implants and more particularly to combining and interconnecting various femoral and tibial prosthetic components with prosthetic stems.
Resection of either the femur or tibia requires implantation of a distal or proximal component to replace the resected bone. Depending on how much bone is to be resected, an additional segment may need to be implanted along with the component. These components and segments are held to the remaining healthy bone through the use of a stem, which is inserted into the intramedullary canal of a skeletal member. There are many stem configurations available to suit anatomical and surgical needs. Because it is important to keep as much healthy bone as possible, and due to patient anatomical diversity and physician preferences, economic component versatility


is of considerable importance.
Versatility is limited in that the femoral and tibial components of one product line are often incompatible with the stems of the same and/or a different product line. Currently, an adaptor and stem are incorporated into a single implant device. The adapter portion is used to attach the stem portion to the femoral and tibial components and/or segments. Using such a single piece device creates design limitations and an increased expense in manufacturing customized pieces to meet patient needs, and increases the inventory and number of parts required to be on hand.
Also, in order to include a porous coating on the adapter portion, the single device is heated to a very high temperature during the manufacturing process that may weaken the stem portion. Because ofthis, the single implant devices with smaller stem diameters cannot be manufactured with the porous coating without compromising the strength of the stem.
Consequently, what is needed is a universal adaptor to act as an interface between various stems and prosthetic devices, thereby allowing for more combinations of the implant devices and therefore, more versatility.
One embodiment, accordingly, provides a surgical implantation device which is useful for interfacing a multitude of stem choices to mate with otherwise incompatible prosthetic devices used in femoral and tibial replacement or bone conserving surgery. To this end, a prosthetic component includes an adaptor having a first end and a second end. The first end includes an elongated male tapered body. The second end includes a flange extending radially outwardly from the male tapered body


The New York City Shakespeare in the Park production of “Julius Caesar” was interrupted by two protestors with one being arrested. Now, supporters of President Donald Trump are backing the hashtag #FreeLaura. Right-wing activist and Rebel Media’s Laura Loomer livestreamed herself rushing the stage. By midnight, Loomer had posted she had been released from jail.

Nonetheless, social media users were debating who actions that resulted in her being charged with trespassing and disorderly conduct.

According to her video, she rushed onto the Delacorte Theater stage during the scene where Caesar is assassinated and yelled “stop the normalization of political violence against the right! This is unacceptable … this is violent!” The crowd mainly yelled for her to get off the stage or booed as she compared the production to ISISlow. When the display field is to be moved skipping many days, a long time is required. By holding down the right or left scroll buttons 41b or 41a, the same effect as continuous clicking can be obtained, but such operation is by no means convenient.
By contrast, when the scroll box 41c is used, the display field can be quickly moved to information of a schedule part corresponding to the dropped position of the scroll box 41c on the scroll bar 41. However, in order to display a schedule for a desired day on the screen, the user experiences difficulty in determining the dropping position of the scroll box 41c. As a consequence, the user must gradually move the display field using the right or left scroll button


41b or 41a, or the scroll box 41c to adjust the display position while confirming the screen.
It is an object of the present invention to improve scroll operability upon displaying information for a desired interval of time when a display field is scrolled along the time axis for information such as a Gantt chart on a computer.
In order to achieve the above object, a scroll display method on a time axis according to the present invention, comprises the steps of: displaying GUI operation members consisting of calendar information on the screen; and moving the screen display field along the time axis to display at least information corresponding to a date indicated by the operated GUI operation member on the screen upon operation of one of the GUI operationshow the world what’s inside.

Today we have print venues with magazines, newspapers and books although opportunities there are shrinking. There is also the gallery wall. The internet has opened countless possibilities for space and venues. But telling stories for the internet requires some of the same story-telling techniques and widens the possibilities for our photographic approach. Multi-media is the future, some say, but just putting photographs to audio does not necessarily make a good story. Nothing is better than a well-told, well-thought-out approach. That’s what our workshop is about and you will have to find a story or theme to work on and we will critique the work daily and also look at work by many other photographers in various arenas. It doesn’t matter if you are photographing


Inc. San Diego, USA) at 5 × 10^3^ cells per well with 150 μL complete medium. After growing 24 h, the medium was replaced by fresh medium containing various concentrations of PBNPs and incubated for another 96 h. This system measured the electrical impedance, which was created by cell attachment on the microelectrode-integrated cell culture plates \[[@CR20]\], to provide the quantitative information about the cell number and viability in real time by the RTCA-DP instrument \[[@CR21]\]. Cellular proliferation was measured periodically every 15 min for the following 4 days.

Real-Time Monitoring of Cellular Migration {#Sec9}
------------------------------------------

C3H10T1/2 cell migration was measured using a real-time cell invasion and migration (RT-CIM) assay system (ACEA Biosciences, Inc. San Diego, USA). Cells have the ability of increasing the impedance to hence "Cell Index" read-outs when they contact and adhere to the sensorsand some other studies also demonstrated the surface modification of PBNPs enhances its performance in MRI \[[@CR17], [@CR26]\]. Currently, PBNP labeling has been used in a variety of cells. Dumont et al. described PBNPs as agents for MRI and fluorescence-based imaging of pediatric brain tumors \[[@CR27]\]; Perera et al. developed the gadolinium-incorporated PBNPs for the early detection of tumors in the gastrointestinal tract \[[@CR28]\]; and Cano-Mejia et al. combined Prussian blue nanoparticle (PBNP)-based photothermal therapy (PTT) with anti-CTLA-4 checkpoint inhibition to treat neuroblastoma \[[@CR29]\]. However, there is rarely related reports on PBNP-labeled MSCs. Additionally, whether there is any negative influence on cell function and viability of MSCs after labeling PBNPs remains unclear

To investigate whether the PBNPs have the ability to enhance the T2-weighted MRI contrast of cells, we


of Frauds is inapplicable to this evidentiary dispute.
The parol evidence rule is a rule of substantive law recognized by Ohio courts to prevent a party who has entered into a written contract from contradicting the terms of the contract by introducing evidence of prior understandings and negotiations. Ed Schory & Sons, Inc. v. Francis, 75 Ohio St.3d 433, 662 N.E.2d 1074, 1080 (1996). The defendant argues that the rule prohibits the plaintiff from offering proof that the monthly obligations are anything other than spousal support.
In considering whether a payment pursuant to a separation agreement is alimony, maintenance or support for purposes of Section 523(a)(5) of the Bankruptcy Code, the parol evidence rule is inapplicable and the Court's inquiry is not limited to the four corners of the agreement.also get the chance to go horse riding in the wilderness around the town of Wales where Oxbow is located.

While there are computers at the school, they are modified so that the only websites accessible from them are online encyclopaedias.

Dining room: The residents are subjected to a rural and simple lifestyle in the Utah wilderness

Group therapy: Music is one of the extra-curricular activities intended to help them overcome their problems

The teenagers are encouraged to open up about their past problems - and are even subjected to a lie detector test to ensure they are not concealing anything from the therapists.

Stephen Schultz, director of Oxbow Academy, told the Sunday Mirror that the boys - some of whom have been convicted of sex attacks - were like drug addicts going


reporting capabilities, and you have existing Excel assets, you may wish to convert them to the native Power BI format. Whatever the reason, moving from Excel to Power BI is relatively straightforward with Power BI Desktop.

From the File menu in Power BI Desktop, select Import, and then Excel Workbook Contents.

You are then prompted to select an Excel file. Once selected, you are then presented with a warning dialog.

The dialog does a very good job of explaining what will happen, specifically the fact that data from workbooks will not be brought into this new file. Any Power Pivot data models or Power Queries will be brought in. If the workbook contains legacy Power View sheets, they will be converted to native Power BI visuals. In addition, any legacy (non-Powerthe event had been postponed until June 2 due to scheduling conflicts with Yiannopoulos’ other tour dates (he had originally been scheduled to appear on May 24), but Rowlands reassured those interested in attending that she had spoken with administrators, who told her the university has “no intention of shutting it down whatsoever.”

Follow the author of this article on Twitter: @FrickePete


being comprised of male/male, female/female and male/female athletes. The event organizers have created a series of WODs that have been tested and re-tested to ensure balance across movements and time domains. You will enjoy this event, the t-shirt and the judging! Pick your partner and get your team registered before this event sells out!be present ([Figure 2](#pntd-0000462-g002){ref-type="fig"}).

![Incorporating disease sequelae into the model.\
A schematic representation of the way in which the model determines the presence of disease sequelae: trachomatous scarring (TS) and trachomatous trichiasis (TT) (TS and TT---but not corneal opacity, CO---are considered to be caused exclusively by reinfection with *C. trachomatis*). The simplest scheme is used: thresholds exist, along the ladder of infection, beyond which each of the sequelae are assumed to be present. Beyond the threshold corresponding to a specific sequela, that sequela is assumed to be observed, e.g. when the threshold for TT has been reached, both TT and TS are observed.](pntd.0000462.g002){#pntd-0000462-g002}

Infection and Disease Prevalence {#s2d}
--------------------------------

The model was fitted using maximum likelihood to pre-intervention prevalence and chlamydial load data collected in studies carried out in The Gambia and Tanzania,


back to finish second in the NASL standings before topping North Carolina FC in the semifinal round and defeating the Cosmos in the title match. Notably, their season also included training sessions at San Quentin State Prison and splitting two games with the San Jose Earthquakes.

Still, the club seemingly struggled financially. Citing low attendance and a preference for transparency, club CEO Brian Andrés Helmick penned a piece on Medium pleading Delta fans “just came back with one friend!”

The Deltas surged late in the campaign, outscoring opponents 19-8 on a late-season stretch in which it went 6-0-4 to help negate its 1-3-1 start to the year. Despite then losing its regular season finale, SF shut out North Carolina and New York in the playoffs — the latter victory inspiring571 F.2d 1376
17 Fair Empl.Prac.Cas.  447, 16 Empl. Prac.Dec. P 8275Sarah Henson JAMES et al., Plaintiffs-Appellees,v.DELTA AIRLINES, INC., Defendant-Appellant.
No. 76-2581.
United States Court of Appeals,Fifth Circuit.
April 28, 1978.

Gordon Dean Booth, Jr., Wm. H. Boice, J. Dianne Brinson, J. Stanley Hawkins, Sidney F. Davis, Legal Dept., Delta Air Lines, Inc., Atlanta, Ga., for defendant-appellant.
John Walter Henderson, Jr., Atlanta, Ga., for plaintiffs-appellees.
Appeal from the United States District Court for the Northern District of Georgia.
Before GOLDBERG and SIMPSON, Circuit Judges, and FREEMAN, District Judge.*
PER CURIAM:

1
Plaintiffs, thirteen female flight attendants, filed this suit pursuant to Title VII of the Civil Rights Act of 1964, as amended, 42 U.S.C. §§ 2000e, et seq., alleging that their employer, Delta Air Lines, discriminated against them on the basis of their sex.  Each plaintiff had


The returning cyclist is a delusional fool. Despite a sustained period with next to no cycling, we emerge from our winter hibernation with memories of our summer form whilst conveniently ignoring the winter feasts hanging around our blubbery middles. After remembering how to dress in Lycra again, we set off on the bike, confused by the heavy feeling in our lead legs, bemused by the pain in our chests.

Pains best known to the beginner cyclist return. Your bum hurts. So too your arms, neck, hands, ankles and knees. What is this, this hurting thing, you wonder, as if you’ve just stepped out of The Matrix and landed back in Zion. Like Neo, you too could do with downloading a few hundred miles of simulated training.

Rest days and neglect

Idlenesshorses, unless their operator is doing stupid things like charging at other horses while carrying a pointed stick. As a rule, I'm guessing horses are safer per passenger mile.

somitomi wrote:Humans are in fact outstanding at driving - so good, that we've become very overconfident, which is the real cause of most human error behind the wheel (drinking/texting and driving, for example.)

I very strongly disagree with this. Humans are absolutely atrocious drivers.

We forget a huge amount of the rules.Have slow reaction times.Only manage 1 thing at a time. ( True multi-tasking is very rare, and even that might just be very fast task switching and good management. )Vision is heavily designed to ignore/fake vast amounts of the information it takes in and has large blind spots.Only look in a


and even that might just be very fast task switching and good management. )Vision is heavily designed to ignore/fake vast amounts of the information it takes in and has large blind spots.Only look in a single direction at a time.Have a strong tendency to overreact in stressful situations.Only see in a very narrow range of light, which mostly disappears at night, and many things are similar colored.Easily get relaxed, losing focus.Easily distracted.Are overconfident as you mentioned.

Consider this: All driving exams and tests are extremely thorough, require 100% to pass, and are required every year. If you are ever found at fault in an accident, your driving privilege is revoked. If you are ever caught breaking any law ( even just rolling through a stop sign, clipping a solidautomatically? Change the route then. Scared of heights, so you want to avoid that Cliff? Go for it. Speed up? Can do. All of these already exist on Teslas automated systems here and now. You're now combining humans decision making, with the advanced capabilities of the automated system. Let it handle the tedious, mundane, etc. You can focus on the big picture. Everyone wins.

So, yea. We are really bad at driving. Automated IS better than we are at driving, especially when you add in what few pros we have to it.

There is no reason at all to not be pushing automated advancements right now. The sooner we can get switched over to full auto, the better.

If you're hoping to switch over to full auto any time soon, you'll


speed turned down while testing, to give the human inside more time to react when the car makes a mistake ( since it's being tested, IE isn't entirely ready for prime time. And before anyone tries to complain about testing on an open road...that's exactly how we teach and test humans too, because a simulation just can not compete with the real world. )

I'm also not saying we should force self driving on everyone here and now. I'm just saying that people should admit that we are not as capable as we like to think in driving cars, and that we should help not hinder efforts to develop automation.

zemerick wrote:Nearly all traffic is caused either by poor human driving habits, or by accidents. We could handle 10 timesleasing' arrangements, on a 'buy in on ownership or move on to another car' end-of-contract basis. I think the trend might be to supercharge the very-nearly-new resale end of the car market, satisfying bleeding-edge customers with new vehicles and just-off-the-bleeding-edge buyers of barely-used cars getting a higher proportion of the (re)sales, perhaps mostly at the expense of the middle-ground inhabited by medium-age 'clean diesels' that have since been shown to have been erroneously/ill-advisably marketed and may be swallowed up by manufacturer buy-back/scrappage schemes (while post-catalytic/pre-big-diesel-lie era vehicles scrappage or enter 'classic' status in similar proportions as before.

somitomi wrote:In my experience driving is one of those things practice makes perfect, so I fail to see how the time spent on practicing driving with a trained instructor before getting your


off. And I don't think they come with all those benefits, either. Two six-lane roads intersecting, with all the traffic that entails, cannot move that traffic through the intersection at speed, both ways, collision-free, without some kind of major slowdown or management system. And autonomous cars will always be programmed to err on the side of caution.

I would add that it's not quite true that vehicle-miles-traveled (VMT) has been flat in the time frame you describe. Going from 2.95 trillion to 3.095 trillion is a 5%-ish jump. 145 billion is no small thing. Combined with the accident stats you quote, our crash rate is one accident per 491,582 miles traveled. Yes, it's up from one every 552,641 miles traveled. Still, that kind of failure rate would be consideredlifespan, that matters. Average lifespan is brought down by driving your shiny new car off the lot and smacking a tree a mile down the road. That doesn't really change the penetration into the market of a new technology. What matters is whether people adopt it, and they don't do so when they go looking for a $2000 set of wheels because that's the most they can afford. The question is not whether a Chevy Cobalt (or pick your model) lasts 6, 12, or 20 years, it's whether there's a Chevy Cobalt available to buy when someone wants a cheap used car. There always is.

sonar1313 wrote:If you're hoping to switch over to full auto any time soon, you'll likely be very disappointed. If I see it in my


of course) I agree completely. Gun safety is another thing humans are remarkably good at, the breathless coverage of every stray bullet notwithstanding. There are tens of millions, possibly over a hundred million, gun owners in the US (not counting those who have them illegally), and as you can see almost all of them manage to handle them without putting a bullet in someone else.

Presumably that is where the data comes from, and what little data they show makes nearly all disengagements appear to be driving at least as safely as a human.

The other assumption is that "all humans" drive at "human ability".

I can assure you that in my first 5,000 miles of driving, a Waymo computer would take the wheel out of my hands a number ofto reduce flooding deaths, why would they make driving tests harder to reduce car crash deaths?

zemerick wrote:Nearly all traffic is caused either by poor human driving habits, or by accidents. We could handle 10 times the number of cars if they were driven by computer systems.

Huge [citation needed] on that figure.

I accept that the number of cars could increase a bit if all of them were connected and computer driven, but not by anything like a factor of 10.

And the increase in capacity would probably be more than countered by the increase in cars being used when we don't have to drive them ourselves. Ridesharing already has increased traffic problems in many cities, and this would add to that problem.

For highway traffic, this should be trivial to compute


reg_ref, persistent_ref;
	char buf[32];
	long ret;

	/* Look in the register if it exists */
	index_key.type = &key_type_keyring;
	index_key.description = buf;
	index_key.desc_len = sprintf(buf, "_persistent.%u", from_kuid(ns, uid));

	if (ns->persistent_keyring_register) {
		reg_ref = make_key_ref(ns->persistent_keyring_register, true);
		down_read(&ns->persistent_keyring_register_sem);
		persistent_ref = find_key_to_update(reg_ref, &index_key);
		up_read(&ns->persistent_keyring_register_sem);

		if (persistent_ref)
			goto found;
	}

	/* It wasn't in the register, so we'll need to create it.  We might
	 * also need to create the register.
	 */
	down_write(&ns->persistent_keyring_register_sem);
	persistent_ref = key_create_persistent(ns, uid, &index_key);
	up_write(&ns->persistent_keyring_register_sem);
	if (!IS_ERR(persistent_ref))
		goto found;

	return PTR_ERR(persistent_ref);

found:
	ret = key_task_permission(persistent_ref, current_cred(), KEY_NEED_LINK);
	if (ret == 0) {
		persistent = key_ref_to_ptr(persistent_ref);
		ret = key_link(key_ref_to_ptr(dest_ref), persistent);
		if (ret == 0) {
			key_set_timeout(persistent, persistent_keyring_expiry);
			ret = persistent->serial;
		}
	}

	key_ref_put(persistent_ref);
	return ret;
}

/*
 * Get the persistent keyring for a specific UID and link it to the nominated
 * keyring.
 */
long keyctl_get_persistent(uid_t _uid, key_serial_t destid)
{
	struct user_namespace *ns = current_user_ns();
	key_ref_t dest_ref;
	kuid_t uid;
	long ret;

	/* -1 indicates the current user */
	if (_uid == (uid_t)-1) {
		uid = current_uid();
	} else {
		uid = make_kuid(ns, _uid);
		if (!uid_valid(uid))
			returnto prevent attempts to game the system, but both are valid concerns.
The best you get is this answer from Shog9 discussing the implementation of the feature, which says, in part (emphasis added):

Here's how it works:

There are two thresholds:

Number of votes cast by the user being deleted
Number of people affected significantly by those votes

The exact values of those thresholds don't particularly matter;
  they're pretty low, but not so low that you could hit them easily
  while still hiding fraudulent activity.
If either threshold is exceeded, deletion is held up until someone reviews it. Otherwise, deletion proceeds and any votes are discarded.
If, during review, it becomes apparent that the user is or ever was involved in voting fraud, the votes are discarded as they would
  normally be.
Otherwise, the


are performing as well, or even better, academically than their private counterparts.

Sports Programs – Though some private schools are known for their competitive athletic programs, the majority have trouble sustaining a wide array of specialty teams due solely to the relatively small number of students. For the parents of some budding athletes, public school is simply the best choice.

Cultural Diversity – Many parents prefer the melting pot of race, religion and socioeconomic status that is public school over the often less-diverse private schools. Instead of keeping their kids isolated in a group of students from almost identical backgrounds, many parents choose the diversity of public education.

They Live in the Suburbs – Real estate agents know that one of the strongest selling points of a home is being inthat countries can evaluate infractions before any sort of a vote or decision can be made to determine if there even has been any infraction,” the Bennet said.

Also speaking to Press TV, Mohammad Taghi Hosseini (shown above), an expert in international affairs in Tehran, also told Press TV that it is not "to the benefit of the United States or to the benefit of any other party" to have the previous resolutions automatically re-imposed again "because there is a mechanism for it and the mechanism is not automatic."

"So I do not believe that any wise politician, any wise decision maker would be in favor to break everything and also again going to the previous situation and re-imposing sanctions on Iran," he said.

Netanyahu, his usual self

Meanwhile, hawkish Israeli Prime


probably find it on the web. Contrary to popular belief you don't need general relativity as special relativity is perfectly capable of handling accelerations, as long as you're content to treat acceleration as absolute. My recollection of doing the calculation at college is that it was messy and actually not very illuminating.

p}_3 = -{\vec p} + \frac12{\vec p}_{23} \,
- \frac{{\vec p} \cdot {\vec p}_{23}}
{ \left[
\omega \left( \vec p \, \right) + \sqrt{ \omega \left( \vec p \, \right)^2
+ {\vec p}^{\ 2}_{23} }
\right]
 \omega \left( \vec p \, \right)  } \, {\vec p}_{23} .
\label{p3}\end{aligned}$$

The two additional factors $ {\cal N }  ( {\vec q}^{\, \prime} , -{\vec q} - {\vec q}^{\, \prime} \, )$ and ${\cal N } ( -{\vec q} - {\vec q}^{\, \prime} , {\vec q} \, )$ in Eq. (\[Faddeevrelmom\]) which generally can be written as [@gloeckle86] $$\begin{aligned}
{\cal N }( {\vec p}_2, {\vec p}_3) = \left\vert {\partial ({\vec p}_2
 , {\vec p}_3 ) \over \partial ( {\vec p}, {\vec p}_{23} )}
 \right \vert ^{\frac12}
=
 \left( 4E_2 E_3 \over {\sqrt{ (E_2 +


sufficient and we will show now how to obtain the relativistic wave function components $\psi_\alpha ( p , q ) $ from Eq. (\[Psi\]). To this aim we derive and apply a version of the relativistic operator $P$ “working to the right”. As usual it is sufficient to consider only one overlap, for example ${}_1 \langle {\vec p} \, {\vec q} \mid {\vec p}^{\ '}
{\vec q}^{\ '} \rangle_2$. We restrict ourselves to the 3N c.m. system and express the individual momenta ${\vec p}_{1}$, ${\vec p}_{2}$ and ${\vec p}_{3}$ in terms of ${\vec p}$ and $ {\vec q}$ using Eqs. (\[p2\]) and (\[p3\]) $$\begin{aligned}
{\vec p}_1 =  {\vec q}
\label{p1.2}\end{aligned}$$ $$\begin{aligned}
{\vec p}_2 =  {\vec p} - \frac12{\vec q} \,
+ \frac{{\vec p} \cdot {\vec p}}
{ \left[
\omega \left( \vec l'_ 2   \lambda'_ 1 \lambda'_ 2   } $ is strictly the same (under the neglection of the Wigner spin rotations) as we use for example in [@Pright]. Consequently, the 3N bound state wave function components can be easily calculated.

We would like to give the reader an example of the difference between the nonrelativistic and relativistic wave function and show the single-nucleon momentum distribution in Fig. \[fig0\].

We see that differences visible on a logarithmic plot appear only for $ q\gtrsim $ 3 fm$^{-1}$. Most important effects are just due to the relativistic kinematics. The approximation given in Eq. (\[approxboost\]) does a very good job since the dashed and solid lines nearly overlap. The boost effect is visible for $ q\gtrsim $ 6 fm$^{-1}$. The results presented


the nonrelativistic limit $$\begin{aligned}
   {\vec p} \rightarrow \frac12 \left( {\vec p}_2 - {\vec p}_3 \, \right)
\nonumber \\
   E_i \rightarrow m \nonumber \\
   {\cal J} \rightarrow 1
\label{Ei}\end{aligned}$$

The second and third observables we investigate here are special cases of the helicity asymmetry $ A ( {\vec S} ) $ $$\begin{aligned}
A ( {\vec S} \, ) \equiv
\frac{\sigma ({\vec S} , h=+1) - \sigma ({\vec S} , h=-1)}
{ \sigma ({\vec S} , h=+1) + \sigma ({\vec S} , h=-1) },
\label{A}\end{aligned}$$ under the same kinematical conditions as the unpolarized cross section in Eq. (\[sigma6\]) and obtained from the corresponding polarized semi-exclusive cross sections $ \sigma ({\vec S} , h) $. We consider $A_\parallel$ for $ {\vec S} \parallel  \hat{z}$ and $A_\perp $ formodel. Also for this asymmetry the PWIA and FSI23 predictions take very simple shapes at the first two kinematics, while the full inclusion of FSI leads to more complicated structures. The perpendicular asymmetry for the neutron knockout process is very sensitive to the neutron electric form factor so also in this case the values for the maximal neutron energies, especially at the $k3$ and $k4$ kinematics, are determined predominantly by the neutron electric form factor values. This explains why in the neutron case the parallel asymmetry is much bigger than the perpendicular one.

For the $k5$ and $k6$ kinematics there is a clear gap between the pure nonrelativistic FSI23 result and the predictions employing relativistic kinematics and the relativistic current operator. This is partly due to the arguments of


the electromagnetic form factors, which differ for these two approaches. In the nonrelativistic case we simply take $ \omega^2 - {\vec Q}^{\, 2}$ which does not correspond to the true four-momentum transfer felt by the nucleon. In the relativistic case we (exactly) account for the four momentum transferred to the nucleon using the following form $$\left( \sqrt{m^2 + \left( {\vec p} +  {\vec Q} \right)^{\, 2}}  - \sqrt{m^2 + {\vec p}^{\ 2}} \right)^2
-  {\vec Q}^{\ 2} ,$$ where $ {\vec p} $ is the nucleon momentum prior to photon absorption.

Finally, in Figs. \[fig7\] and \[fig8\], we show the six fold differential cross sections for the neutron and proton knockout. Both, for the proton and neutron knockout, the cross sections vary by many orders of magnitude. Thereestimate the effects of these new relativistic ingredients. We found out that the bulk of relativistic effects comes from the relativistic kinematics. Further (consistent with kinematics) relativistic features of the calculation are less important. For the kinematics within the shaded area of Fig. 3 ($k1$, $k2$, $k3$, $k7$, $k8$), even in the neighborhood of the highest energy of the ejected nucleon, the FSI23s and the full FSI are different. Therefore the full FSI treatment is mandatory for a quantitative analysis. On top, especially for the $k7$ and $k8$ kinematics some relativistic effects are noticeable and should be included in the future analyzes of correspondingly precise data. For the kinematics $k5$ and $k6$ in the range of highest nucleon energies the relativistic effects are clearly visible, especially for neutron emission,


R1483 (1996).

J. Golak, W. Glöckle, H. Kamada, H. Wita[ł]{}a, R. Skibiński, A. Nogga, Phys.Rev. C[**66**]{}, 024008 (2002).

G. Höhler, E. Pietarinen, I. Sabba-Stefanescu, F. Borkowski, G. G. Simon, V. H. Walther, and R. D. Wendling, Nucl. Phys. [**B114**]{}, 505 (1976).

T. W. Donnelly, A. S. Raskin, Ann. Phys. (N.Y.) [**169**]{}, 247 (1986).

J. Golak, H. Wita[ł]{}a, R. Skibiński, W. Glöckle, A. Nogga, H. Kamada, Phys. Rev. C[**70**]{}, 034005 (2004).

R. Skibiński, H. Wita[ł]{}a, J. Golak, nucl-th/0604033.
Introduction {#s1}
============

As there were an estimated 1.2 million (range, 1.1--1.3 million) tuberculosis (TB) deaths among HIV-negative people in 2018 \[[@C1]\] TB can still be considered to be the top infectious killer worldwide. Although the epidemiological situation of TB in low-incidence countries has improved over the past few years, employees in unprotected contact with infectious TB patients in healthcare facilities are at considerable risk of *Mycobacterium tuberculosis* transmission \[[@C2]\]. Current guidelines suggest a bundle of complementary infection control measures for reducing such transmission. Recommendations for such control measures have been established by the World Health Organization (WHO) and authorities in the United States of America (USA), the United Kingdom (UK) and in Germany, the latter three serving as references for other low-incidence countries. How the positions and priorities set


for fully susceptible TB and were therefore culture-positive at this time point. Accordingly, the authors concluded that persistent smear positivity at day 60 is only a poor predictor of MDR-TB and not a good surrogate for drug susceptibility testing. Thus, waiting for at least one culture conversion from positive to negative before relaxing isolation appears to be an indispensable criterion for judging infectivity in MDR-TB treatment.

Periodic testing of HCWs for latent TB infection {#s1f}
------------------------------------------------

Although most interventions aimed at preventing MTB transmission in healthcare facilities focus on known or suspected TB patients under effective treatment or on their close contacts, unsuspected and/or undiagnosed and therefore initially untreated patients are the primary source for transmissions to HCWs \[[@C4], [@C32]\]. Serial testing, annually or in perennial intervals, intends to detect suchQ:

css transitions not working for css grid-column and grid-row properties?

I want to add a transition when the mouse hover the item. i tried using the CSS transition property but it dose not working. My code is simple what i wanted to do is, i have four squares when hover one of them i should cover the other three and take the size of all four squares.
(eg: for a portfolio)
Check my code below i found it easy to do with css grid layout but im new to css grid. Can someone tell what is wrong with my code or alternative to do my task.thank you
<!DOCTYPE html>
    <html lang="en">
    <head>
        <meta charset="UTF-8">


(MEPs) greater than 50 μV.

### TMS sessions {#Sec15}

A Magstim Rapid^2^ device (Magstim®, UK) and Magstim D70-mm air-cooled real/sham coil will be used to administer real and sham rTMS. Before each rTMS delivery, participants in both groups will watch a short film showing highly palatable foods, which will function as cue exposure to disorder-related stimuli.

#### Delivery of real rTMS {#FPar3}

Patients in this group will receive 20 sessions of high-frequency rTMS (10 Hz) at 110 % of their individual MT, consisting of twenty 5-second trains with 55-second inter-train intervals delivered to the left DLPFC \[Talairach co-ordinates x = −45 y =45 z = 30 \[[@CR58], [@CR68]\].

#### Delivery of sham rTMS {#FPar4}

Sham stimulation will be given at the same parameters as the real rTMS; however, a sham coil will be used. The sham coil makes the sameweekly during treatment.Offline neuropsychological tasks assessing: i) inhibitory control as assessed by a proactive inhibition task \[[@CR84]\] will be completed at baseline, post-treatment and 3-month follow-up, while ii) attentional bias to food using the visual probe task (VPT) \[[@CR85], [@CR86]\] and iii) food choice behaviour tasks (FCT) \[[@CR87]\] will be conducted at baseline and post-treatment.Questionnaires assessing: i) impulsivity/compulsivity and self-regulation, that is, Delaying Gratification Inventory (DGI) \[[@CR88]\], Barratt Impulsiveness Scale (BIS-11) \[[@CR89]\] and Obsessive-Compulsive Inventory (OCI-R) \[[@CR90]\], and ii) cognitive control of emotions and self-efficacy, including the Eating Disorder Recovery Self-Efficacy Questionnaire (EDRSQ) \[[@CR91]\], Emotion Regulation Questionnaire (ERQ) \[[@CR92]\] and the Cognitive Flexibility Scale (CFS) \[[@CR93]\] assessed at baseline, post-treatment and 3-month follow-up, and iii) quality of life (EuroQol Quality of Life Scale EQ-5D-5 L \[[@CR94]\]) and illness impact


large-scale RCT will be based on a number of criteria. These include the number of patients we are able to recruit, the proportion of patients retained in the study, the proportion of patients completing the real rTMS/sham intervention, the acceptability of real rTMS/sham intervention and the effect sizes of treatment outcomes. At the end of the study, these factors will be used by the study team to decide the case for progressing to a substantive RCT.

### Clinical outcomes {#Sec29}

Analyses will use the intention-to-treat principle. To determine quality, completeness and variability of the outcome measures, descriptive statistical analyses and graphical methods will be used. The size of the treatment effect on each outcome measure (BMI, questionnaires, neuropsychological processes) will be the difference in outcome data between those in thehighlighted by a school record 12 this year. Nine players have collected freshman All-America honors and 24 have garnered freshman All-Big Ten recognition.Wilson's offenses have set 47 school records, including single-season points, total yardage, passing yardage and rushing yardage. Indiana led the Big Ten in total offense, scoring offense and passing offense, the first team since Ohio State in 1995 to do so.IU (2015) became the fourth team in FBS history with a 3,500-yard passer, two 1,000-yard rushers and one 1,000-yard receiver in the same season, joining 2005 Southern California, 2008 Oklahoma and 2015 Southern Miss. The Hoosiers had two 1,000-yard rushers for the first time in program history and were one of two Power Five teams (Baylor) to accomplish that feat this season.Indiana won its final two


Q:

Is the ordinal number "zuerst" only acceptable in colloquial speech and writing?

While practicing writing this sentence fragment (“First you must select a good cookbook, then ...”) in German using each of my two ‘silent tutors’(translate.yandex.ru and translate.google.com) to check the correct way to say or write that fragment I found that the translations returned by my two tutors was functionally the same, but that they had differences in word order and familiarity with the person to whom my sentence fragment might have been directed.
Here is what my two tutors had replied:

(Yandex):  Zeurst müssen Sie wählen Sie ein gutes Kochbuch, dann ...
(Google):  Zeurst musst du ein gutes Kochbuch auswählen und dann ...

In checking my German, my Russian tutor (Yandex) returned my sentence in ‘polite’ word usage, whileindia

Updated: Feb 14, 2019 00:03 IST

The Congress’s organisation structure in Uttar Pradesh is likely to be a challenge for Priyanka Gandhi Vadra, the general secretary incharge of east UP, as she continues to interact with party workers to firm up a strategy for the general elections.

“I am learning a lot about how to restructure the organisation and the changes needed to be made on the road ahead. I’m also getting their views on how to fight these elections and win them,” she said, having held a marathon round of meetings starting 1pm on Tuesday till about 5.30 am on Wednesday.

“We have no organisation at the grassroots level. But we have to go to polls with the present organisation. We have had a jumbo-sized Uttar Pradesh Congress Committee of


blocs/ for different blocs that manipulate objects between repositories and UI and ui/ for UI components.

We will have nothing inside api/ and models/ , but they can be used by the *_repository.dart files for fetching and storing data in appropriate format. Our page data will be just String and int that we will generate locally within repository files.

Repositories

Our FirstPageRepository class will be responsible for providing data contained in the first page and SecondPageRepository will provide data for second page. Simple enough. Let’s implement those classes:

class FirstPageRepository {

String _data;

Future<void> fetchData() async {

// simulate real data fetching

await Future.delayed(Duration(milliseconds: 600));

// store dummy data

_data = 'First Page';

}

String get data => _data;

}

And the second…

import 'dart:math';

class SecondPageRepository {

int _data;

Future<void> fetchData() async {

// simulate real data fetching

await Future.delayed(Duration(milliseconds: 600));

// store dummy data

_data = Random().nextInt(1000);

}

int getas members so BLoC doesn’t have to deal with how the data is being fetched, via network or locally and what not. BLoC’s responsibility is to get the data, decide what to do with it and send appropriate states to the UI. This is done inside mapEventToState method.

UI

The last thing to do is to write the UI components for this app.

Pages

We start of with pages. They will be StatelessWidget that just render themselves with data they are constructed with.

import 'package:flutter/material.dart';

class FirstPage extends StatelessWidget {

final String text;

FirstPage({this.text}) : super();

@override

Widget build(BuildContext context) {

return Scaffold(

body: Center(

child: Text('My text is: $text'),

),

);

}

}

And the second…

import 'package:flutter/material.dart';

class SecondPage extends StatelessWidget {

final int number;

SecondPage({this.number}) : super();

@override

Widget build(BuildContext context) {

return Scaffold(

body: Center(

child: Text('My number is: $number'),

),

);

}

}

AppScreen

This StatelessWidget redraws its body and bottomNavigationBar depending on the state yielded


will feed your curiosity, but it still leaves you wanting for more to know more. Excited for the next episode,” YouTube user Ma. Isabel Cura commented.

“A lot of moral lessons can be picked up from this. We should value any kind of person and do good to our fellowmen,” said another YouTube user April Romel Caro.

Viewers are in for more surprises this Sunday (May 5) as Mateo and Iking face each other in an arnis battle. Despite having a poor eyesight, Iking will impress Mateo with his abilities, urging the latter to ask for a rematch. But before their fight ends, Iking will run away to make sure his enemy will not see his transformation into a human bat.

Will Mateo discover Iking’s secret?

Don’t miss “Hiwaga ng Kambat” everyaromatic porphyrin-like macrocycles, the tripyrroledimethine-derived "texaphyrins" which absorb strongly in the tissue-transparent 730-770 nm range. The photophysical properties of metallotexaphyrins parallel those of the corresponding metalloporphyrins and the diamagnetic complexes sensitize the production of .sup.1 O.sub.2 in high quantum yield.
Acquired immunodeficiency syndrome (AIDS) is among the most serious public health problems facing our nation today. AIDS, first reported in 1981 as occurring among male homosexuals,.sup.60 is a fatal human disease which has now reached pandemic proportions. At present, sexual relations and needle-sharing are the dominant mechanisms for the spread of AIDS..sup.60 Since the testing of blood supplies began, the percentage of AIDS infections due to blood transfusions has dropped considerably..sup. 60,104-107 However, an absolutely fail-proof means must be developed to insure that all stored blood samples are free


Introduction {#JVEv4-sec-0006}
============

Lassa fever (LF) is a viral haemorrhagic fever (VHF) endemic to countries in West Africa. It is a zoonotic disease whose animal reservoir is the 'multimammate rat', a rodent of the genus *Mastomys*, which shed virus in their urine and faeces [@JVEv4-bib-0001]. LF is known to be endemic in Benin, Ghana, Guinea, Liberia, Mali, Sierra Leone and Nigeria [@JVEv4-bib-0001].

The clinical course of the disease is variable and made difficult by the wide spectrum of clinical manifestations, ranging from asymptomatic to multi-organ system failure and death. The overall case-fatality rate is 1% while the observed case-fatality rate among patients hospitalised with severe forms of LF is 15--50% [@JVEv4-bib-0001].

Lassa virus is classified as a Biosafety Level 4 (BSL4) and National Institutes of Allergy and Infectious Disease (NIAID) Biodefense categoryIn this study, we report our experience on the clinical presentations and outcomes of these cases.

Materials and methods {#JVEv4-sec-0007}
=====================

We performed a retrospective analysis of the 10 children with suspected LF at the Paediatrics Department of Jos University Teaching Hospital (JUTH) between June and August of 2017. Ethical approval was obtained from the Ethics Committee of JUTH.

LF was suspected in patients presenting with: fever of less than 3 weeks' duration that had not responded to antimalarials or antibiotics, and myalgia, prostration or abdominal pain as well as history of contact with any patient with LF. Each patient had a detailed history and physical examination documented.

The diagnosis of LF was confirmed with an RT-PCR test performed at the national reference laboratory at Lagos University Hospital, Lagos. In addition, all cases


samples, the risk of nosocomial spread of the disease can be reduced significantly.

PCR was used to test for LF virus and six of the 10 patients with clinical suspicion of LF were found to be positive. It is important to note that complementing the PCR by antibody testing would further improve the reliability of the diagnostics, thereby reducing the number of missed diagnoses. Antibody testing detects infected patients in the convalescent stage when the viral load has dropped below the limit of detection for PCR [@JVEv4-bib-0014].

Conclusion {#JVEv4-sec-0010}
==========

Lassa fever, an endemic VHF in our environment, should be suspected in any patient presenting with fever unresponsive to antimalarials, antibiotics and other treatments and especially if associated with the clinical signs of prostration, tachypnoea, tachycardia and abdominal tenderness. Standard precautions atThe detailed steps of study selection were summarized in [Figure 1](#f1-dddt-13-539){ref-type="fig"}.

There were 18 studies from Asian countries (12 from China, six from Japan) and 13 studies from Western countries (six from America, three from the Netherlands, two from Canada, one from Germany, and one from the Czech Republic). Among all the included studies, 17 analyzed the benefits of neoadjuvant taxane-based therapy (neoadjuvant chemotherapy, NACT: seven studies; neoadjuvant chemo-radiotherapy, NACRT: 10 studies), 11 studies analyzed the clinical benefits of taxane-based dCRT, and three studies analyzed the benefits of both dCRT and NACRT in EC. Taxane-based regimens included taxane-based monotherapy (paclitaxel/docetaxel), two-drugs, or three-drugs therapy. The radiation doses for dCRT and NACRT ranged from 36--70 Gy and 36--69 Gy, respectively. HRs for OS and PFS could be directly or indirectly


comparing paclitaxel+5-FU with FP. Taxane-based dCRT resulted in better short-term clinical response (CR: pooled OR=0.57, 95% CI=0.38--0.85, *P*=0.006; ORR: pooled OR=0.58, 95% CI=0.42--0.79, *P*=0.0005; and DCR: pooled OR=0.49, 95% CI=0.29--0.893, *P*=0.008) and survival (PFS: pooled HR=0.74, 95% CI=0.64--0.85, *P*\<0.0001; and OS: pooled HR=0.73, 95% CI=0.63--0.85, *P*\<0.0001) compared to FP dCRT ([Table S2](https://figshare.com/s/6bbd5bf021bd243a847a)). However, taxane-based dCRT caused higher rates of grade 3/4 leukopenia (pooled OR=1.80, 95% CI=1.30--2.49, *P*=0.0004) and pneumonia (pooled OR=2.32, 95% CI=1.23--4.38, *P*=0.009; [Table S3](https://figshare.com/s/6bbd5bf021bd243a847a)).

Discussion
==========

Nowadays, meta-analysis has become a very popular and powerful tool in evaluating the benefit or disadvantage of an intervention. Through pooling data from quantities of individual studies, meta-analysis could overcome limitations of small sample sizes or rare outcomes and increase the generalizability of study results. In addition, meta-analysis uses a process of computingwill require some more maintenance and can’t handle as much pressure! I recommend model numbers (SS) 2S025-1/4H and (ABS) 2P025 1/4S both models come with a choice of power options for the actual Solenoid part. Type 1 is the 12VDC, 2 are 24VDC, 3 110VAC and 4 is 220VAC the best choice for a tool like this I think are the 12VDC they require more amperage but nothing a mosfet and heatsink cant handle. In this example I used the 110VAC version as I had a couple on hand at the time of the build!

After that you need a front end kit of syringes and needles I like this one its a great deal for the price! and something to control the valves with, In the example it


relays(such of some commercial units).

In the specific case of the DIY Solder Paste Dispenser the process flows like this. the compressor is attached to the “front” panel via standard air compressor hook ups. This makes it really easy to quickly connect/disconnect and use basically anywhere.

The compressed air enters the first solenoid valve and is held back by it. From here the tubing branches to the syringe in one route.

And to the “exhaust” valve on the other end of the Tee.

As the button is pushed the exhaust valve is closed (if open) then the intake valve is opened and the syringe is pressurized. When the button is released the intake valve is closed and the exhaust valve is opened releasing all the pressure in the syringe. The amount ofThe bishops and their allies aren’t celebrating with us that the country’s huge unmet contraceptive need and rising rate of HIV infections may soon be somewhat ameliorated. Instead, they are busy planning the downfall of the legislators who courageously withstood the many statements that “contraception is corruption.”

Supporters of the RH bill celebrate after it passed Congress. (Jay Directo/AFP/Getty Images via The Guardian)

The recently signed Reproductive Health Bill (RH Bill), promising to greatly expand contraceptive access in the Philippines, was a victory almost 15 years in the making. For more than five years, I worked with Catholics for Reproductive Health, a group central to the fight against those other Catholics against RH, otherwise known as the Catholic Bishops’ Conference of the Philippines (CBCP). The bishops and their allies aren’t


who were rejected by voters. Others, such as Congresswoman Janette Garin, co-author of the RH Bill, have been elected despite being targeted by local priests and bishops. Promising to defeat pro-RH policymakers in the May election, the bishops issued a statement encouraging Catholics to become politically active. One such lay initiative is Catholic Vote Philippines, which is developing a database comparing politicians’ votes with a version of Catholic doctrine heavily slanted against reproductive health. This is an odd strategy, given that policymakers who helped pass the bill garnered a tremendous amount of positive publicity, in part because they proved stronger than the bishops’ no-holds-barred assault. But the CBCP’s decision to turn up the political pressure seems like more of the same. It also illustrates that the bishops arepoor studies of Filipino psychology.

In my country, people love cheering the underdog. By threatening a massive show of force during the May elections, the hierarchy is flexing its political muscles, and citizens are likely to recoil. Everyone knows that the institutional church has a tremendous advantage in its well-developed infrastructure, which can funnel information from the bishops’ conference at the top through the dioceses and into the ears of those parishioners who are forced to listen to politically-slanted pastoral letters read in the place of homilies. The bishops are also no strangers to the media. But what is missing from their didactic statements is the sort of messaging at which the pro-RH movement excels.

The legislators and advocates who made the RH Bill a reality were well served by


post-conviction relief, and requested attorney Daniels to further explicate defendant's allegation that an insufficient factual basis had been presented at the proceeding to accept defendant's guilty plea. After hearing defense counsel's argument on the issue, the court invited a response from the State. Assistant State's Attorney Schoenbein argued that the State, relying on the transcript of defendant's grand jury proceedings, had borne its minimal burden sufficient *485 to survive defendant's challenge to the factual basis. The court stated that it agreed with the State's position and found the factual basis to be sufficient.
Continuing, the court announced that it did not find defendant's sentence excessive. With respect to the allegation that defendant's plea was entered involuntarily, the court stated that "any fact that would be alleged would be diametricallyA few days ago, Argentinians commemorated the one-year anniversary of the death of rock idol Gustavo Cerati. The singer’s premature death from a brain hemorrhage after a concert in Caracas, Venezuela’s capital, left his fans across South America despondent and searching for answers.

The revered rock star had the unfortunate fate of falling ill in Venezuela. A new book on Cerati makes a strong case that the singer was a victim of Venezuela’s never-ending collapse.

The author of Cerati: La biografía, Argentine journalist Juan Morris, claims Cerati did not get the right medical attention. As it became evident that Cerati’s brain was hemorrhaging, he was taken to one of the best private clinics in Caracas – the Centro Médico Docente La Trinidad. The clinic, though, didn’t have electricity, was lacking


2018 on course to be worst in a decade for youth violence

30th November, 2018

This year is on course to be the worst in a decade for the number of children stabbed to death, according to figures released yesterday by the Guardian. 37 children and teenagers have been stabbed to death in England and Wales this year alone,

With violence continuing on an upward trend, I spoke to John Humphrys on the Today Programme about the work the Youth Violence Commission is doing to tackle rising levels of youth violence.

You can listen to the full interview below or find out more about the work of the Youth Violence Commission on our website: www.yvcommission.comconditioning unit breaks down, the detectors can overheat during CT scanner use. Further, the air conditioning units are not readily removable. Their position within a CT scanners makes it difficult to repair other CT scanner parts and features by inhibiting free access to such parts.
The present invention contemplates a new and improved apparatus which overcomes all of the above-referenced problems and others.


ANAHEIM, Calif. – One of the better games in a dismal Anaheim Ducks season marked the end of the Randy Carlyle era.

Carlyle was fired after Wednesday's 4-1 victory against the Montreal Canadiens at the Honda Center and replaced by former Washington Capitals coach Bruce Boudreau.

Anaheim also jettisoned assistant coaches Mike Foligno and Dave Farrish in a clean-house move after a 2-12-4 run over the previous 18 games marked the worst stretch in Carlyle's seven-year tenure.

The organization made the announcement about an hour after the game ended and neither Carlyle nor Ducks players were available to comment. ESPN.com's Pierre LeBrun tweeted that general manager Bob Murray informed Carlyle 40 minutes after the game, and Murray then met with the team leaders.

Anaheim, ironically, finally played a 60-minute game.

Much-maligned captain Ryanpuck penalties by Anaheim. But the Canadiens managed just three shots on goal total during the advantage.

"They were a desperate team and we did some things early on, and we got going the right way," Gill said. "We let a few things creep back into our game and they have some skill players that make plays. We couldn't get the job done on the power play and we gave up some (power-play) goals."


had no better choice when he had opportunity
to leave work and leave home.

~~~
wanderingstan
A few years ago I was cutting it close for a flight from New York to Maine.
Everyone else had boarded when I got to the gate. When my wrinkled, self-
printed boarding pass threw error noises, the agent told me just to go, "and
run!" I breathed a sigh of relief when I was on the plane, but puzzled that a
French tourist was in my seat. When we saw that both our tickets had the same
seat we called over a flight attendant. "Wait, where are you flying?" she
asked. "Portland, Maine?" With this comment I now fully understand the terror
came to her face as she exclaimed, "This plane is going to Paris! Sir, you
have to get off this planeand is a
concentration of wealth and influence. By letting Snowden stay in HK, China
can appease its own population while also appearing to stand strong against
the US government's demands.

The best hope for the USG is that this blows over. Snowden seems fairly savvy
about the media's role and if he's able to continue to shape the discussion
there might actually be meaningful outcomes.

~~~
rayiner
> The "China is an oppressive regime" meme

It's not a meme. It's fact.

~~~
cloudwizard
This brings up the idea that Snowden fled the US to a place that he felt would
be more free.

~~~
chatmasta
HK != China

~~~
mhurron
Hong Kong is China and has been since 1997.

~~~
seclorum
One country, two systems.

------
rayiner
> According to an interview with The Guardian, 29-year-old Edward Snowden,
> whose revelations have created a political uproar, has stashed himself in an
> unidentified luxury hotel


HK that is more supportive?

~~~
EthanHeilman
>I'm sure there are cameras and one is easily recognized when getting out of
the room.

All those cameras and employees become a protection. Remember when Israel
assassinated that arms trafficker in a luxury hotel and all the video footage
was released to the internet. It blew ~10+ operatives cover and caused a major
diplomatic row about the fake passports used.

If the US took action at the hotel the cost in terms of US covert operatives
in China blown would be in 10-100s of millions of dollars in training and
recruitment. If the US used a third party they would expose that third party
to Chinese intelligence. Not including the media firestorm such an action
would cause.

All security is about raising the cost to the attacker, he has raised it
significantly but the USyards a game the last 8 games of the season.

_________________

Fri Mar 19, 2010 4:21 pm

bobby0112

2015 Phinfever VIP Donor!

Joined: Tue Jan 12, 2010 11:35 amPosts: 1550Location: Lakeland, Fl

Re: Ricky switches to Rosenhaus, plans to play beyond 2010

He has a great work ethic and has been a model citizen since coming back. Man he sure filled the void last year when Ronnie went down. I just pull for the guy because he is trying to do the right thing. Having Patrick Cobbs come back healthy will add even more depth this year.

_________________

Fri Mar 19, 2010 5:04 pm

eleaf

Phinfever Legend

Joined: Wed Jan 13, 2010 1:49 amPosts: 4147Location: The Bluegrass

Re: Ricky switches to Rosenhaus, plans to play beyond 2010

Iowafin wrote:

Big Dave wrote:

Why do you all love him so much?

He carried the ball 775


require the officer who implements the order to venture beyond the surface of the body.
We do not believe that defendant's argument captures the essence of Towne. In establishing the line beyond which probable cause is required, we relied in Towne on State v. Kirchoff, 156 Vt. 1, 10, 587 A.2d 988, 994 (1991), for the proposition that Article 11 protects persons from governmental intrusion into affairs they chose to keep private. We also relied upon the analysis of Skinner v. Railway Labor Executives' Ass'n, 489 U.S. 602, 617, 109 S.Ct. 1402, 103 L.Ed.2d 639 (1989), which, while evaluating a requirement to give a urine sample, noted that the passing of urine is done privately, as a matter of both social custom and law. The point of our analysiswas that persons cover pubic hair as a matter of personal privacy, and are often required to do so by law.
Although the inside of one's mouth is often hidden from public view, exposing it does not entail the embarrassment and social discomfort which accompanies the sexual and excretory functions associated with the pubic area. See United States v. Nicolosi, 885 F.Supp. 50, 55 (E.D.N.Y. 1995) (expectorating not viewed with same disfavor nor concealed behind closed doors as urinating; therefore, saliva lacks attendant expectation of privacy surrounding urination). Indeed, by talking and yawning, we frequently expose the interior of our mouth to public view.
Nor do we find controlling significance in the fact that saliva is taken from a body cavity. By this argument, defendant is attempting to liken the


Craig Gleason 🔪 · BXruLgGj24t

Media share

12.08.17 - 08:09❤ 3285

80,000 followers, baby! I need to take a minute to thank each and every single one of you for the constant support. These past 3 years have been really weird and surreal. I'm going to do everything in my power to keep putting out freaky new characters, and keep things fresh and interesting for the people who stick around.
Repost this image for the chance to win my next 8 shirt designs totally free.
Use the hashtagpart that the property could not be acquired until a public hearing was held and that property acquisitions for the highway were scheduled to begin in *259 1973 and 1974.[1] The property was eventually taken. Four years elapsed from the time of the initial notice, June, 1969, to the time of "actual taking."
The plaintiff alleges that during that four-year period, as a result of the defendants' notifications and delays in actually taking the property, he was denied and deprived of the common, reasonable and necessary use and enjoyment of his property, that his rights of ownership were interrupted, that he was restrained from continuing the use of his land in that he refrained from and ceased construction of the building and was denied the mortgage after it was


committed to him, and that he was denied and deprived of his right to carry on and expand his business. He claims damages for his being prevented from constructing the building. He further claims special damages for loss of profit, interest *260 on the mortgage loan of $7681.31, real estate taxes of $1339.17, an inspector's fee of $47, $300 for a survey, $435 for upkeep of the land and $445 for attorneys' fees.
The defendants filed a motion to erase in which they set up the doctrine of sovereign immunity as a bar to the jurisdiction of the court. The court granted the motion and erased the action from the docket.
A motion to erase a case from the docket will be granted only when the face of the recordNew Field Initiated Study

A new field initiated study was just posted. Therapeutic Reading Programs and Reading Education Assistant Dogs is a compilation of responses received from Samantha Hagar’s inquiry to the Libnet listserv on how libraries use dogs in therapeutic reading programs.

For more information, click the title above or visit our Field Initiated Studies section.


Q:

Cannot get my Custom Android View to display

I am trying to create a custom control which does nothing except decorate the text which is displayed.  When I reference this class inside the main.xml like all the examples which I am reading and deploy this to the emulator, the widget just says "Problem Loading Widget."
I am beginning Android development and just trying to understand how to dev custom controls:
This is the ExtendedTextView control:
package uk.co.andrewrea.android;

import android.content.Context;
import android.util.AttributeSet;
import android.widget.TextView;

public class ExtendedTextView extends TextView {

    public ExtendedTextView(Context context) {
        super(context);
        // TODO Auto-generated constructor stub
    }

    public ExtendedTextView(Context context, AttributeSet attrs){
      appositions were synapselike contacts between labelled boutons and unlabelled structures containing flattened or pleomorphic vesicles, and occasional dense-cored vesicles. (6) We observed no unequivocal axosomatic contacts made by labelled boutons. (7) The lengths of synaptic appositions with dendritic spines (0.46 +/- 0.20 micron) or with dendritic shafts (0.51 +/- 0.18 micron) were significantly greater than the synapselike contacts with vesicle-containing unlabelled structures (0.29 +/- 0.09 micron). (8) Complex neuropilar organization was occasionally seen with labelled boutons as central elements, although simpler organizations were much more common. In summary, HRP-labelled fibers ended predominantly in boutons containing clear, round vesicles forming axospinous and axodendritic synapses.(ABSTRACT TRUNCATED AT 400 WORDS)


Select Local Merchants

Historian, curator, and classic-car buff Tanya Bailey-Smith opened the Great Savannah Races Museum as an homage to the cultural significance of the Great Savannah Races of 1908, 1910, and 1911. Her facility doubles as a micromuseum and gift shop with media and fine-art items on display and a collection from the Automobile Club of America, whose members chose Savannah to host the first American Grand Prix.

Built in 1842, The Harper Fowlkes House incorporates many of the popular styles of the era, such as an exterior of Savannah gray brick stuccoed and scored to resemble stone blocks. Visitors can still see the craftsmen?s handiwork during educational tours of the three-story Greek Revival mansion, held four days a week. A curving stone staircase leads to the mansion?s fronte);
			resp.setStatus(AjaxResponse.RESPONSE_STATUS_FAIURE);
		}

		String returnString = resp.toJSONString();
		final HttpHeaders httpHeaders= new HttpHeaders();
	    httpHeaders.setContentType(MediaType.APPLICATION_JSON_UTF8);
		return new ResponseEntity<String>(returnString,httpHeaders,HttpStatus.OK);
	}

	private void setMenu(Model model, HttpServletRequest request) throws Exception {

		//display menu
		Map<String,String> activeMenus = new HashMap<String,String>();
		activeMenus.put("shipping", "shipping");
		activeMenus.put("shipping-configs", "shipping-configs");

		@SuppressWarnings("unchecked")
		Map<String, Menu> menus = (Map<String, Menu>)request.getAttribute("MENUMAP");

		Menu currentMenu = (Menu)menus.get("shipping");
		model.addAttribute("currentMenu",currentMenu);
		model.addAttribute("activeMenus",activeMenus);
		//

	}

}


and 5. Led by a man called "Thor," the mob kidnapped the children and transported them into an underground place of demon worship via a river of blood. The children were placed on a sacrificial altar and then beaten with rods adorned with nails. Our house expert on Satanism, Nile Burenblit states, "When you think about it, all these people were doing is demonstrating their faith in eternal hellfire. Who can blame them?" Switzerland's District Attorney office appeared reluctant to file charges, although they feel the removal of the nails from the steel murder weapons would be sufficient punishment.Lugano Police Chief Jil Diument disagrees. "This is outrageous. These devout Satanists are having their rights stripped from their necks. Remove the nails? For what?" The people of Lugano seemfavorable to defendants, a reasonable jury could not conclude that Gould engaged in fraudulent conduct.

1. Common Law Fraud

To succeed on their counterclaim for common law fraud, defendants must prove: "(1) a misrepresentation or a material omission of material fact which was false and known by [Gould] to be false, (2) made for the purpose of inducing [defendants] to rely on it, and (3) justifiably relied upon by the [defendants], (4) who then suffered an injury as a result of such reliance." City of New York v. Smokes-Spirits.Com, Inc., 541 F.3d 425, 454 (2d Cir.2008). A claim for fraud cannot stand where the only allegation is "that the defendant entered into a contract with no intention of performing." Grappo v. Alitalia Linee Aeree Italiane, S.p.A., 56 F.3d 427, 434


and hemicellulosic substrates. Furthermore, our strains grow using either the cellulose or hemicellulose components of ionic liquid-pretreated biomass or on both components when combined as a coculture. Both cellulolytic and hemicellulolytic strains were further engineered with three biofuel synthesis pathways to demonstrate the production of fuel substitutes or precursors suitable for gasoline, diesel, and jet engines directly from ionic liquid-treated switchgrass without externally supplied hydrolase enzymes. This demonstration represents a major advance toward realizing a consolidated bioprocess. With improvements in both biofuel synthesis pathways and biomass digestion capabilities, our approach could provide an economical route to production of advanced biofuels.

The microbial conversion of sustainable lignocellulosic biomass into biofuels could provide a source of fully renewable transportation fuels (1). Generating these fuels from abundant feedstocks such as lignocellulose andcellulosic waste avoids many of the problems associated with current grain-based biofuels, provided the feedstock is responsibly grown and harvested (2). While early efforts toward achieving economical biofuel production have typically focused on improving yields of ethanol made from fermentation of plant sugars (3), recent advances in metabolic engineering have enabled microbial production of fuels that are compatible with existing engines and fuel distribution infrastructure (4, 5). Many of these advances have been made possible by the unparalleled genetic and metabolic tractability of the model bacterium Escherichia coli (6, 7). E. coli has been engineered to biosynthesize perhaps the most chemically diverse range of chemicals of any organism, including hydrogen (8), higher alcohols (9, 10), fatty-acid based chemicals (11), and terpenes (12, 13). Extensive knowledge of E. coli


of lignocellulose is the organism’s inferior capacity for protein export, which renders it unable to secrete cellulases in quantities required for industrial-scale lignocellulose hydrolysis. Various techniques, developed over decades of research, can be applied to generate secreted yields from E. coli of 0.5–0.8 g protein/L (21). Unfortunately, these concentrations are still too low for an industrial process, which are most efficient around levels of 20 mg cellulase/g solids and 200 g/L solids loading (22) [although recent work (23) has demonstrated that removal of soluble hydrolase inhibitors may substantially reduce the enzyme loading required]. To further engineer a cellulolytic E. coli strain for use in consolidated bioprocessing, biofuel production pathways must also be introduced and expressed at levels that yield high titers while not overburdening the cell. The integrationrecently found in a cow rumen metagenome (36), and these enzymes could be screened to find either replacements for or supplements to the hydrolysis activity of Cel and Xyn10B enzymes. Furthermore, protein export pathways that do not compromise the cell membrane (as our OsmY fusions may be doing) should be used instead to avoid compromising cellular fitness and biofuel yields. Along with chromosomal integration of the biomass-consumption pathways (as opposed to encoding the pathways on plasmids), these steps should also improve the genetic stability of our modifications as well as their suitability for industrial-scale fermentations. In parallel with optimizations of the E. coli strain, the IL pretreatment could be modified to render the lignocellulose completely susceptible to hydrolysis by the GH enzymes we used here. For instance, acid


catalysis during IL pretreatment of cellulose has been shown to dramatically increase the extent of subsequent enzymatic hydrolysis (37). These improvements will be required to fully realize the cost savings of a consolidated bioprocess that could provide a versatile platform for producing any advanced biofuel from any plant biomass at economical yields.

Materials and Methods Selection, Optimization, and Screening of Cellulase Genes. The set of cellulases was chosen to maximize diversity within family 5 endocellulases. First, the CAZy database was used to collate all known family 5 enzymes (38). At the time this work was done, there were 689 such enzymes in the database. The enzymes were aligned using Muscle (39) and then 10 were selected to maximize diversity using HyperTree (40). The 10 genes were then optimized for(quoting Blum v. Stenson, 465
U.S. 886, 896 (1984)). As noted, COWPTA does not define
"oil produced from tar sands," but "where Congress has
used technical words or terms of art, it is proper to explain
them by reference to the art or science to which they are
appropriate." Corning Glass Works v. Brennan, 417 U.S.
188, 201 (1974) (internal quotation marks and alterations
_________________________________________________________________

production methods available in 1980 as crude oil subject to the windfall
profit tax. But the discussion of Title I in the legislative record
indicated
that Congress considered "oil produced from tar sands" to be synthetic
petroleum, which Congress distinguished from crude oil. Therefore, the
Tax Court concluded that oil producible using tertiary recovery methods
could not be tar sand oil unless Congress had intended to give different
meetings to the term "oil produced from tar sands" as


until 1983 but asserts that, in
1980, petroleum engineers agreed that "tar sand oil" was oil
too viscous to be produced using primary production
methods (the "primary production definition"). Furthermore,
Shell maintains that petroleum experts in 1980 were able
to identify tar sand and tar sand oil by inspection. Shell
calls this experience-based identification of tar sand oil the
"qualitative standard." According to Shell, the viscosity
standard was a conservative quantification of the earlier
primary production and qualitative definitions. 11 Because
the trial court made no findings with respect to the other
proposed definitions or their relationships to the viscosity
standard,12 Shell seeks a remand to determine whether the
qualitative or the primary production definition was widely
accepted by the industry in 1980 and whether the Potter
Sands oil meets those definitions.

But Shell did not properly assert these additional
industry definitions at trial. Inpretrial orders are liberally construed
to permit the parties to advance their cases, see United
States Gypsum Co. v. Schiavo Bros., 668 F.2d 172, 181
n.12 (3d Cir. 1981), and an issue can be tried by consent
when testimony relevant to the issue is introduced without
objection, see Douglas v. Owens, 50 F.3d 1226, 1236 (3d
_________________________________________________________________

13. Many of these passages are themselves not properly before us,
because Shell has not included them in the appellate record. The
appellant is required to provide a record to support the claims it makes
on appeal. See Fed. R. App. P. 10(b), 11(a); Scarfo v. Cabletron Sys.,
Inc.,
54 F.3d 931, 963 (1st Cir. 1995); Schmid v. United Bhd. of Carpenters,
827 F.2d 384, 386 (8th Cir. 1987); United States v. Hart, 729 F.2d 662,
671 (10th Cir. 1984). Based on the excerpts Shell


has quoted to us, the
passages outside the appellate record on which Shell relies are no
stronger than those in the record.

                               10
Cir. 1995). But a party still must unequivocally put its
position before the trial court at a point and in a manner
that permits the court to consider its merits. See Keenan v.
City of Philadelphia, 983 F.2d 459, 471 (3d Cir. 1992)
("[T]he crucial question regarding waiver is whether
defendants presented the argument with sufficient
specificity to alert the district court"); Portis v. First Nat'l
Bank, 34 F.3d 325, 331 (5th Cir. 1994) ("The raising party
must present the issue so that it places theof Philadelphia, 35 F.3d 840, 845 (3d Cir.
1994) (internal quotation marks omitted). Finding no
"compelling circumstances" requiring consideration of
_________________________________________________________________

was commonly expressed as oil that could not be commercially produced
through a well using primary recovery methods." Post-trial briefs are not
generally appropriate places to raise one's theory of the case. In any
event, this brief also fails to assert Shell's position clearly. The
sentence
just quoted was followed by an assertion that the industry shared "[a]
common understanding that the line of demarcation at which tar sand
oil became more viscous than heavy oil needed to be established
quantitatively" and was contained in a section entitled, "The Court may
consider the industry and government expert development of the 10,000
cp viscosity distinction between tar sand and other heavy oils in applying
the earlier enacted 26 U.S.C. S 29 for `oil


defendant does not have any notice that the
implied claim was being tried.").

15. Furthermore, to promote orderly trial procedures, appellate courts
are sensitive to the importance of respecting the pretrial order on
appeal.
See Correa v. Hospital San Francisco, 69 F.3d 1184, 1195 (1st Cir.
1995).

                               12
Shell's theories, we decline to exercise our discretion to do
so. See American Bearing Co. v. Litton Indus., 729 F.2d 943,
949-50 (3d Cir. 1984).

Furthermore, our review of those portions of the record
Shell has brought to our attention leads us to conclude
that the possibility the District Court would find the facts
as Shell describes them is remote. The strongest evidence
Shell                              16
the legislative history, the District Court found that
Congress did not consider crude oil to be tar sand oil, nor
would Congress have imposed an excise tax and granted a
tax credit to the same type of oil in the same statute.
Because Shell's Potter Sands oil was indisputably crude oil
subject to the windfall profit tax, we hold, like the District
Court, it cannot also be tar sand oil eligible for the tax
credit.

1

On this point, the legislative history is instructive. In its
report on Title I (imposing the windfall profit tax), the
Senate Finance Committee specified, "The term `crude oil'
. . . applies only to


oil would be characterized as oil
produced
       from tar sands for purposes of title II. While the reference to tar

                               18
Shell does not contest the District Court's finding that its
Potter Sands oil is tertiary oil, Shell's oil cannot be tar sand
oil eligible for the tax credit.

2

The logic and structure of the act also demonstrate that
crude oil is not tar sand oil. If oil producible using
enhanced recovery methods, including the oil produced at
Potter Sands, were classified both as crude oil and as tar
sand oil, it would be subject to the windfall profit tax and
alsoeligible for the nonconventional source tax credit. The
District Court declined to interpret the statute this way
"[a]bsent some evidence that Congress intended such an
anomalous result." Shell, 996 F. Supp. at 371. We agree.
See United States v. McKie, 112 F.3d 626, 631 (3d Cir.
1997) (discussing courts' "obligation to construe statutes
sensibly and avoid constructions which yield absurd or
unjust results").

Shell defends its interpretation by pointing out that
under COWPTA the windfall profit tax was phased out as
the price of oil fell whereas the nonconventional fuels credit
was phased in under the same conditions. Shell suggests
that the tax collected in years when oil prices were high
was to be used to finance the subsidy when oil prices fell.
Essentially, Shell suggests that the tax and credit together
functioned as a rough-and-ready producer price
stabilization scheme. But the legislative record


 expressing an intent to do so.

101 T.C. at 580.

                               19
transfer windfall crude oil profits to producers of a distinct,
"alternate," class of energy sources. Furthermore, Shell
concedes that, on its reading of the statute, oil produced
from Potter Sands would have received both a tax and a
credit in 1981 and 1982. If Congress had sought to
stabilize producer prices for tar sand oil, we do not see why
Congress would have imposed a tax and provided a subsidy
in the same year.20 Therefore, we believe the District Court
correctly found that Congress did not intend to classify the
same oil as both taxable crude oil                        -3-

[*3] The issues in this case are based on a substantial writedown of properties

held by petitioner’s solely owned S corporation, Paragon Homes Corp. (Paragon),

in 2008.

       Paragon was a residential land development and home building company

that owned several properties in Hillsborough County, Florida. These properties

consisted of multiacre tracts, platted subdivisions, lots and single-family homes.

Petitioner was the president, director, and sole shareholder of the company. In

2004-06, the years at issue, Paragon was a solvent company duly meeting its

payroll, mortgage obligations, rent, insurance premiums, real estate taxes, and

utility bills.

       Paragon executed mortgages with several banks,


filing the return for the taxpayer’s last
taxable year beginning in 2009. See sec. 172(b)(1)(H)(iii).
                                        - 10 -

[*10] II.     Petitioner’s Claimed Net Operating Loss Deduction From 2008

        Petitioner claimed a net operating loss deduction for tax year 2008 and

elected to carry back the loss to tax years 2003-06. Most of this loss comes by

way of petitioner’s wholly owned S corporation, Paragon. At the end of 2008

Paragon wrote down the value of its real property holdings because of the decline

inin a prior year. Helvering v. Hammel, 311

U.S. 504, 512 (1941); George v. United States, 124 F.3d 216, 80 A.F.T.R.2d

(RIA) 97-6286 (10th Cir. 1997); Commissioner v. Green, 126 F.2d 70, 71-72 (3d
                                        - 12 -

[*12] Cir. 1942); Middleton v. Commissioner, 77 T.C. 310, 323 (1981)

(recognizing the difference between real property subject to recourse debt and

nonrecourse debt for purposes of an abandonment loss), aff’d, 693 F.2d 124 (11th

Cir. 1982).

      Although petitioner admits that Paragon’s mortgage obligations were

recourse obligations, he argues that Paragon’s investments in its


respect to casualty losses and losses on land due to

abandonment and worthlessness of the property. Paragon’s loss was not a casualty

loss. With respect to a “casualty or other event [that] occurs which may result in a

loss”, the test turns on whether the taxpayer has a reasonable prospect of recovery.

See id. subdiv. (i). Here, petitioner argues that the banks could not reasonably

expect recovery of their loans. Petitioner’s argument mistakes the taxpayer for the

banks and he does not point to any caselaw which interpret the regulations in the

manner he claims. We decline to be the first.

      Furthermore, petitioner’s argument is simply not true. Paragon had funds in

2008 that petitioner transferred a year later to his family limited partnership,

Tucker LLLP, as a way to preclude reimbursementhome on one of its lots. These subsequent attempts in 2009

and 2010 to sell the properties, construct homes, and settle claims with the banks

show that Paragon did not abandon the properties. Furthermore, the properties

could be used to reduce Paragon’s liability exposure for a deficiency judgment.

Hence, the properties were not worthless to Paragon at the end of 2008. Even

petitioner’s expert testified that the properties were not completely worthless at the

end of 2008 and that there was some demand for the properties at that time.

      In summary, petitioner has not met his burden to establish the abandonment

or worthlessness of Paragon’s properties before the foreclosure sale.

      B.     Additional Items Making Up Paragon’s Claimed Loss