Review (5/5): It really works
I have a nagging pain in my left thumb area, when I apply this cream, it takes about 20 minutes and the pain greatly diminishes. It does not completely eliminate the pain, but it makes it so I can actually use my thumb and grip without losing strength. I am happy that I chose this cream, as I have us d DMSO in the past. This lasts for many hours and I forget about it until the pain creeps back in, I am guessing 5 to 6 hours.