Conditions: Leukemia, Myeloid, Acute
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 666
Healthy volunteers: no

Brief summary:
To investigate the efficacy, safety, and pharmacokinetics of intravenous volasertib + subcutaneous low dose cytarabine in patients \>= 65 years of age with previously untreated acute myeloid leukaemia, ineligible for intensive remission induction therapy

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Placebo intervention 2: Volasertib intervention 3: Cytarabine
Intervention descriptions: intervention 1: Placebo matching Volasertib intervention 2: Volasertib intervention 3: Cytarabine

Protocol document: