Conditions: Social Anxiety Disorder
Keywords: propranolol public speaking anxiety
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 6
Healthy volunteers: no

Brief summary:
The study will test the efficacy of propranolol or placebo, administered after retrieval of a previously acquired public speaking fear, in reducing fear and avoidance of public speaking.

Detailed description:
Twenty subjects with Performance-Only type of Social Anxiety Disorder will be enrolled in the study. Participants will complete baseline assessments of fear and avoidance of public speaking. Participants will be randomly assigned to a single dose of propranolol 40mg or placebo, administered immediately after a fear activation procedure. Primary outcome assessment will be self-reported fear of public speaking and avoidance behavior in a behavioral avoidance task 2 weeks after the intervention.

Arms:
arm 1: Propranolol 40 mg capsule, given once after fear activation procedure arm 2: Placebo capsule, given once after fear activation procedure

Interventions: intervention 1: propranolol intervention 2: Placebo
Intervention descriptions: intervention 1: active treatment intervention 2: inactive pill

Protocol document:
Prot_SAP_ICF_000.pdf: