Conditions: Recurrent or Metastatic PD-L1-positive Squamous Cell Carcinoma of the Head and Neck
Keywords: Head and neck cancer; SCCHN
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 112
Healthy volunteers: no

Brief summary:
Primary Objective: To assess the efficacy of MEDI4736 monotherapy in terms of ORR

Detailed description:
This is a phase II, multi-center, single-arm, global study of MEDI4736 monotherapy in patients with PD-L1 positive recurrent or metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN), who have progressed during or after treatment with only 1 systemic palliative regimen for recurrent or metastatic disease that must have contained a platinum agent.

Arms:
arm 1: MEDI4736 monotherapy

Interventions: intervention 1: MEDI4736
Intervention descriptions: intervention 1: MEDI4736 monotherapy

Protocol document: