Conditions: Acne Rosacea
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 100
Healthy volunteers: yes

Brief summary:
This is a prospective, parallel group, randomized, investigator-blinded pilot study. Approximately 100 subjects will be randomized at a 3:1 ratio to Seysara (sarecycline) at a weight-based dose per label or Centrum Adult Multivitamin to take by mouth daily. The study is comprised of 5 visits: screening, baseline, week 4, week 8, and week 12. Investigators will perform rosacea IGA (Investigator Global Assessment,) inflammatory lesion count, record adverse events and con meds, and ask each subject to complete a DLQI (Dermatology Life Quality Index.)

Detailed description:

Arms:
arm 1: weight-based dose per label by mouth once daily for 12 weeks arm 2: one tablet by mouth daily for 12 weeks

Interventions: intervention 1: sarecycline intervention 2: Centrum Adult Multivitamin
Intervention descriptions: intervention 1: sarecycline tablet intervention 2: Centrum Adult Mulltivitamin tablet

Protocol document:
Prot_SAP_000.pdf: