Conditions: Rheumatoid Arthritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 994
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine if abatacept is effective in the treatment of early rheumatoid arthritis.

Detailed description:
Subcutaneous (SC)

Arms:
arm 1: Abatacept 125 mg subcutaneous injection once per week + Methotrexate at least 15mg per week tablet or capsule orally once per week arm 2: Methotrexate at least 15mg per week tablet or capsule orally arm 3: Placebo for Abatacept subcutaneous injection once per week arm 4: Placebo to match Methotrexate capsule orally once per week

Interventions: intervention 1: Abatacept intervention 2: Methotrexate intervention 3: Abatacept Placebo intervention 4: Methotrexate Placebo
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None intervention 4: None

Protocol document: