Conditions: Alcohol Use Disorder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 51
Healthy volunteers: no

Brief summary:
The primary hypotheses under test are that alcohol dependent subjects treated with apremilast will report decreased craving for alcohol following alcohol exposure in the laboratory and report significantly less drinking under naturalistic conditions, than those treated with placebo.

Detailed description:

Arms:
arm 1: Fixed oral dose of 90 mg/d following the standard titration for a total dosing duration of 14 days. arm 2: Identical placebo pills taken orally for 14 days

Interventions: intervention 1: Apremilast intervention 2: Placebo
Intervention descriptions: intervention 1: Fixed oral dose of 90 mg/d following the standard titration for a total dosing duration of 14 days. intervention 2: Identical placebo pills taken orally for 14 days

Protocol document:
Prot_002.pdf: 















































































SAP_003.pdf: 



ICF_004.pdf: