Conditions: Traumatic Brain Injury (TBI) Hazardous and Harmful Alcohol Use
Keywords: TBI hazardous and harmful alcohol use veterans co-occurring disorders pharmacotherapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 32
Healthy volunteers: no

Brief summary:
The goal of the proposed project is to improve the treatment of veterans with co-occurring traumatic brain injury (TBI) and hazardous or harmful alcohol use. The PI and coinvestigators will conduct a pilot controlled clinical trial of topiramate for the treatment of these co-occurring disorders.

Detailed description:

Arms:
arm 1: Topiramate capsules daily - up to 300 mg arm 2: Placebo capsules daily - up 300 mg

Interventions: intervention 1: Medical Management Counseling intervention 2: Topiramate intervention 3: Placebo
Intervention descriptions: intervention 1: Brief alcohol and medication counseling intervention 2: Experimental medication intervention 3: Placebo comparator

Protocol document: