Conditions: Dialysis Cardiovascular Disease Atherosclerosis Inflammation Hyperphosphatemia
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
The hypothesis is that switching calcium based phosphate binders to sevelamer carbonate will be associated with less inflammation including less atherosclerotic plaque inflammation (inflammation of the vessel walls).

Detailed description:

Arms:
arm 1: Sevelamer Carbonate (Renvela). Information including those from the scans and blood test will be compared before and after treatment with Renvela.

Interventions: intervention 1: Sevelamer Carbonate (Renvela)
Intervention descriptions: intervention 1: Patients' will be given doses of Renvela equivalent to their prior dose of calcium based phosphate binders and the dose will be titrated as necessary to achieve phosphate levels recommended by KDOQI guidelines.

Protocol document: