Conditions: Carcinoma, Non-Small-Cell Lung
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: no

Brief summary:
The present trial will investigate the efficacy and safety of nintedanib in combination with docetaxel as compared to placebo in combination with docetaxel in patients with stage IIIB/IV or recurrent NSCLC of adenocarcinoma histology after failure of first-line platinum-based chemotherapy.

Detailed description:

Arms:
arm 1: patients to receive backbone chemotherapy and placebo arm 2: patients to receive backbone chemotherapy and nintedanib

Interventions: intervention 1: docetaxel intervention 2: docetaxel intervention 3: placebo intervention 4: nintedanib
Intervention descriptions: intervention 1: intravenous chemotherapy drug intervention 2: intravenous chemotherapy drug intervention 3: oral placebo intervention 4: oral experimental therapy

Protocol document: