Conditions: Ovarian Neoplasm
Keywords: Advanced ovarian cancer Poly(ADP ribose) polymerases KU-0059436 AZD2281 BRCA1 protein BRCA2 protein
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 58
Healthy volunteers: no

Brief summary:
The purpose of the study is to see if the drug KU 0059436 is effective and well tolerated in treating patients with measurable BRCA1- or BRCA2-positive advanced ovarian cancer and for whom no curative therapeutic option exists.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: KU-0059436 (AZD2281)(PARP inhibitor) intervention 2: KU-0059436 (AZD2281)(PARP inhibitor)
Intervention descriptions: intervention 1: oral intervention 2: oral

Protocol document: