Conditions: Hepatic Carcinoma
Keywords: Huaier Granule; After radical hepatectomy; Prevention of Recurrence and Metastasis; Safety.
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1044
Healthy volunteers: no

Brief summary:
To evaluate the efficacy and safety of Huaier Granule for prevention of recurrence and metastasis of hepatocarcinoma after radical hepatectomy.

Detailed description:
A Multicenter, Randomized, Paralleled control Clinical Study Investigating Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma after Radical Hepatectomy,to evaluate the efficacy and safety.

Arms:
arm 1: Huaier Granule group; specifications: 20g / bag; manufacturer: Qidong Gaitianli Medicines Co., Ltd..

Administration: the Huaier Granule Electuary should be orally taken from the 15th day after surgery. Usage: Huaier Granule Electuary is continuously taken three times per day, 20g per time, until 96 weeks after surgery or until study termination. The subjects should not take any other anticancer drugs or immunomodulatory agents, except for Huaier Granule. arm 2: Blank-control group, not taking Huaier Granule, other anticancer drugs, or immunomodulatory agents.

During the study, patients who need antiviral therapy, in both the test group and control group, can be treated according to the therapeutic principles.

Interventions: intervention 1: Huaier Granule
Intervention descriptions: intervention 1: Huaier Granule is a traditional Chinese medicine, 20g / time, 3 times/day,Po.

Protocol document: