Conditions: Intracranial Aneurysms Seizures
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 17
Healthy volunteers: no

Brief summary:
Seizures are a potential complication of surgical repair of intracranial aneurysms. In order to prevent seizures, many surgeons administer prophylactic anti-epileptic medication during the intra-operative and post-operative period, however, such practice is not supported by clinical data. Retrospective review found the incidence of postoperative seizures was higher in those who received anti-epileptics versus those who did not. The goal is to examine the utility of levetiracetam (Keppra) for seizure prophylaxis in patients undergoing surgical repair of unruptured intracranial aneurysms.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Levetiracetam
Intervention descriptions: intervention 1: 500 mg intravenous dose during the operative case then 500 mg orally twice a day for a total of seven days

Protocol document: