Conditions: Type 2 Diabetes Mellitus
Keywords: insulin resistance
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 139
Healthy volunteers: no

Brief summary:
This extension study was designed to evaluate the safety and efficacy of Canagliflozin (TA-7284) in combination with Insulin in patients with type 2 Diabetes Mellitus. The extension study was an extension to double-blind study of 16 weeks (TA-7284-11)

Detailed description:
This is an open-label extension study to evaluate the safety and efficacy of Canagliflozin (TA-7284) in combination with insulin in Japanese patients with Type 2 diabetes mellitus, who are not optimally controlled on diet and exercise. The patients will enroll from the double-blind study of 16 weeks and receive TA-7284 100mg orally for 36 weeks.

Arms:
arm 1: None

Interventions: intervention 1: Canagliflozin (TA-7284) intervention 2: Insulin
Intervention descriptions: intervention 1: The patients will receive Canagliflozin orally for 36 weeks intervention 2: None

Protocol document: