Conditions: Hematological Malignancies
Keywords: high-risk hematological malignancies
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 78
Healthy volunteers: no

Brief summary:
This is study is for patients that have been diagnosed with high-risk hematological malignancies. The main purpose of this study is to confirm previously published results of stem cell transplantation with reduced intensity pre-transplant conditioning. Patients will be assigned to 1 of 3 regimens depending on the patient's diagnosis. Participants will be followed by the transplant team for the remainder of the patient's life. Patient's will visit MUSC daily, then visits will be reduced to frequent visits for up to 6 months. After 6 months, the visits will be reduced more depending on the patient's condition.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Regimen A intervention 2: Regimen B intervention 3: Regimen C
Intervention descriptions: intervention 1: Chronic Lymphocytic Leukemia/ Chronic Prolymphocytic Leukemia, Multiple Myeloma. intervention 2: Other malignancies not addressed in A or C intervention 3: B-Cell Lymphomas

Protocol document: