Conditions: Dyslipidemia
Keywords: abnormal cholesterol
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 101
Healthy volunteers: yes

Brief summary:
The main purpose of this study is to measure how much of the drug gets into the blood stream and how long it takes the body to get rid of it when given once a day for 12, 24, and 52 weeks to participants with abnormal amounts of cholesterol and/or fat in the blood stream. Information about any side effects that may occur will also be collected.

This study will also evaluate how the study drug reacts in the body when given once a day for 12, 24 and 52 weeks and how the body responds and returns to normal when the treatment is complete. The relationship between study drug and the results from the how the study drug reacts in the body may be explored, if needed.

Detailed description:

Arms:
arm 1: Single oral dose of evacetrapib on Day 1 arm 2: Evacetrapib administered orally once daily beginning on Day 8 for 12 consecutive weeks arm 3: Evacetrapib administered orally once daily beginning on Day 8 for 24 consecutive weeks arm 4: Evacetrapib administered orally once daily beginning on Day 8 for 52 consecutive weeks

Interventions: intervention 1: Evacetrapib
Intervention descriptions: intervention 1: Administered orally

Protocol document: