Conditions: Rapidly Escalating Migraine
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 24
Healthy volunteers: no

Brief summary:
Pilot study to compare the efficacy and safety of two strengths of injections of subcutaneous DFN-11 in subjects with rapidly escalating migraine headaches.

Detailed description:
Pilot study to compare the proportion of subjects experiencing pain freedom at 60 minutes post-treatment between headache treated with Strength A of DFN-11 and Strength B of DFN-11

Arms:
arm 1: DFN-11 (sumatriptan, 3 mg) and placebo first then two DFN-11 injections arm 2: Two DFN-11 (sumatriptan, 3 mg) injections first then DFN-11 injection and placebo

Interventions: intervention 1: DFN-11
Intervention descriptions: intervention 1: Sumatriptan 3 mg versus 6 mg

Protocol document: