Conditions: Diabetes Mellitus
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 212
Healthy volunteers: yes

Brief summary:
Poor bowel preparation and patient intolerance of the procedure are the most important factors contributing to the limitation of colonoscopy. Inadequate bowel cleansing results in incomplete testing, increased potential to miss lesions, increased cost, and decreased patient satisfaction. The investigators hope to gain better insight into which bowel preparation works best in diabetic patients and hence would increase patient satisfaction, tolerability of the bowel preparation and decrease overall costs. The investigators will investigate which bowel preparation for colonoscopy will work optimally in diabetic patients using three different regimens.

Detailed description:

Arms:
arm 1: 4 liters of polyethylene glycol electrolyte lavage solution (PEG-ELS-(GoLytely)+ placebo pill arm 2: split dose(2 L day before procedure and 2 L day of procedure) of 4 liters of Golytely + placebo pill arm 3: split dose (2 L day prior to procedure and 2 L day of procedure) of 4 liters of Golytely + bisacodyl 10 mg

Interventions: intervention 1: Golytely (polyethylene glycol electrolyte lavage solution) and placebo intervention 2: split dose of Golytely (polyethylene glycol electrolyte lavage solution) + placebo intervention 3: split dose of Golytely (polyethylene glycol electrolyte lavage solution) and bisacodyl
Intervention descriptions: intervention 1: 4 liters of polyethylene glycol electrolyte lavage solution (PEG-ELS-(GoLytely))+ placebo given the evening prior to the colonoscopy intervention 2: split dose (2 L taken the evening before and 2 L taken the morning of the colonoscopy) of 4 liters Golytely + placebo intervention 3: split dose ( 2 L taken the evening before and 2 L taken the morning of the colonoscopy) of 4 liters of Golytely + bisacodyl 10 mg

Protocol document: