Conditions: Alcohol Reactivity
Keywords: alcohol reactivity smoking cessation medications
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 44
Healthy volunteers: no

Brief summary:
The purpose of this study is the examine the effect of varenicline on cognition to a high dose (0.08 g/dL) of alcohol (vs. placebo alcohol) over the ascending and descending limb of the blood alcohol curve.

Detailed description:

Arms:
arm 1: varenicline 1mg/day or 2mg/day arm 2: placebo

Interventions: intervention 1: varenicline intervention 2: placebo
Intervention descriptions: intervention 1: 1mg/day or 2 mg/day Subjects are at steady state medication levels. They are participating during the 4-week medication period of our ongoing study, NCT00580645. intervention 2: placebo

Protocol document: