Conditions: Dental Prophylaxis and Implant Surgery
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 38
Healthy volunteers: yes

Brief summary:
The primary objective of this study will be to evaluate the effect of two week pre-surgical rinsing with an antimicrobial mouthrinse containing 0.2% w/v Chlorhexidine digluconate on the total number of plaque bacteria in the mouth 3 days post implant surgery. The study will be conducted at Eastman Clinical Investigation Centre (ECIC), University College London (UCL) Eastman Dental Institute. Participants will be those who require a single and simple surgical implant to be placed, and will be recruited from new patient referrals within the Eastman Dental Hospital

Detailed description:

Arms:
arm 1: Mouthwash containing 0.2% w/v Chlorhexidine digluconate arm 2: Sodium fluoride toothpaste (Aquafresh Mild \& Minty)

Interventions: intervention 1: 0.2% w/v Chlorhexidine digluconate intervention 2: Sodium fluoride toothpaste (Aquafresh Mild & Minty)
Intervention descriptions: intervention 1: Participants will brush their teeth with the reference product (toothpaste) and thoroughly rinse their mouth with water and wait 5 timed minutes before using 10 ml of the 0.2% w/v Chlorhexidine digluconate mouthwash, except when using at site, where no brushing will take place prior to using the mouthrinse. intervention 2: Participants will apply a strip of toothpaste to cover the head of the toothbrush and will brush in their usual manner for two timed minutes twice daily. They will then rinse their mouth thoroughly with water after brushing

Protocol document: