Conditions: Delirium
Keywords: delirium pediatrics critical care quetiapine
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 6
Healthy volunteers: no

Brief summary:
This study is designed to assess the safety and efficacy of quetiapine as treatment for pediatric delirium.

Detailed description:
Many children in the ICU become confused, due to their underlying illness or treatment effects. The medical term for this confusion is delirium. In adults, a medication called quetiapine has been effective in treating delirium. This is considered an "off label" use as the FDA has not approved quetiapine for this indication.

Pediatricians have been using quetiapine to treat delirium in children as well, but there is currently no data proving that it is effective in children. This study is being done to determine if quetiapine is effective for the treatment of ICU delirium in children.

Arms:
arm 1: A randomized group will receive quetiapine as treatment for delirium. arm 2: A randomized group will receive placebo, and not quetiapine.

Interventions: intervention 1: quetiapine intervention 2: Placebo
Intervention descriptions: intervention 1: Patients who are diagnosed with delirium and assigned to the intervention arm will receive quetiapine. intervention 2: Patients who are diagnosed with delirium and assigned to the placebo arm will receive placebo.

Protocol document: