Conditions: Alcohol Use Disorder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 36
Healthy volunteers: no

Brief summary:
The study uses neurobiological measures through brain imaging, neuropsychological measures, and selfreport measures to try to understand how an effective treatment for alcoholism works. On the whole, less than 50% of people with alcoholism get better with treatment. This study will help researchers develop better treatments for alcoholism because if the investigators know why the treatments the investigators use are working, and in whom the treatments work best, then the investigators may be able to make treatment more effective by targeting treatments to individuals who would be most likely to benefit and by guiding development of more effective treatments in the future.

Detailed description:

Arms:
arm 1: Prazosin titrated to 16 mg daily x 6 weeks arm 2: Placebo X 6 weeks

Interventions: intervention 1: Prazosin intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: