Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Chronic Obstructive pulmonary disease, Ivacaftor
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: no

Brief summary:
The study is a randomized, double-blind, placebo-controlled, multiple-dose, pilot study of orally-administered ivacaftor in subjects with chronic obstructive pulmonary disease. Subjects will be administered the study drug ivacaftor 150 mg (or placebo) twice daily (BID).

Detailed description:

Arms:
arm 1: twice a day administration of Ivacaftor: 150mg arm 2: matching placebo

Interventions: intervention 1: Ivacaftor intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: