Conditions: Psoriatic Arthritis
Keywords: Psoriatic Arthritis IL-17 AMG 827 AMG827 Musculoskeletal Disease Spondylarthropathy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 168
Healthy volunteers: no

Brief summary:
The study will examine the safety and effectiveness of AMG 827 for the treatment of psoriatic arthritis

Detailed description:
The study will examine the safety and effectiveness of AMG 827 for the treatment of psoriatic arthritis. Patients will randomly receive either AMG 827 or placebo (a look-a-like liquid that does not have any drug in it) and neither the doctor nor the patient will know what treatment is being given.

Arms:
arm 1: 140 mg AMG 827 arm 2: Placebo arm 3: 280 mg AMG 827 arm 4: AMG 827 SC 210 mg

Interventions: intervention 1: AMG 827 140 intervention 2: Placebo intervention 3: AMG 827 280 intervention 4: AMG 827 210
Intervention descriptions: intervention 1: 140 mg AMG 827 SC (subcutaneous) intervention 2: Placebo SC (subcutaneous) intervention 3: 280 mg AMG 827 SC (subcutaneous) intervention 4: 210 mg AMG 827 SC (subcutaneous)

Protocol document: