Conditions: Thyroid Cancer
Keywords: Caprelsa (vandetanib) ZD6474
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 40
Healthy volunteers: no

Brief summary:
The purpose of this open label, two stage, phase II study is to evaluate the efficacy and tolerability of ZD6474 in patients with locally advanced or metastatic hereditary medullary thyroid carcinoma.

Detailed description:

Arms:
arm 1: Daily oral dose of Caprelsa (vandetanib) 300mg

Interventions: intervention 1: ZD6474 (vandetanib)
Intervention descriptions: intervention 1: oral once daily tablet

Protocol document: