Conditions: Chronic Traumatic Encephalopathy
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 41
Healthy volunteers: yes

Brief summary:
This study will explore the use of flortaucipir as a biomarker for chronic traumatic encephalopathy (CTE) and examine the relationship between clinical presentation and tau deposition.

Detailed description:

Arms:
arm 1: Flortaucipir PET scans in subjects at high risk of developing CTE (former National Football League players) arm 2: Flortaucipir PET scans in former non-contact athletes

Interventions: intervention 1: florbetapir F 18 intervention 2: Flortaucipir F18
Intervention descriptions: intervention 1: 370 megabecquerel (MBq) IV single-dose intervention 2: 370 megabecquerel (MBq) IV single-dose

Protocol document: