Conditions: Allergic Conjunctivitis Seasonal Allergies
Keywords: allergic conjunctivitis seasonal allergies ragweed allergy grass allergy tree allergy NS2 Aldeyra
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 100
Healthy volunteers: no

Brief summary:
This is a randomized, parallel, single center, double masked, vehicle controlled study. The purpose of this study is to determine the activity and safety of NS2 in patients with grass, tree or ragweed-pollen induced seasonal allergic conjunctivitis . Subjects will be randomized 1:1 to receive multiple doses of NS2 Ophthalmic Drops (0.5%) or NS2 Ophthalmic Drops Vehicle (0.0%).

Free aldehydes are thought to be related to inflammatory conditions such as allergic conjunctivitis. NS2, a small molecule aldehyde trap, is being evaluated to determine whether it may decrease inflammation by lowering aldehyde levels.

Detailed description:

Arms:
arm 1: NS2 Ophthalmic Drops (0.5%) arm 2: NS2 Ophthalmic Drops Vehicle (0.0%) control

Interventions: intervention 1: NS2 Ophthalmic Drops (0.5%) intervention 2: NS2 Ophthalmic Drops Vehicle (0.0%)
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: