Conditions: Carcinoma, Hepatocellular
Keywords: Carcinoma, Hepatocellular Proton Beam Radiotherapy Sorafenib
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 8
Healthy volunteers: no

Brief summary:
This study is designed to determine whether proton beam radiotherapy plus Sorafenib compared to Sorafenib alone will produce the best results for treating patients with Hepatocellular Carcinoma.

Detailed description:

Arms:
arm 1: A combination of radiation therapy (proton) to kill tumor cells as well as Sorafenib which is a study drug administered to patients to stop tumor growth. arm 2: Sorafenib is an oral pill taken daily to inhibit tumor growth at the cellular level.

Interventions: intervention 1: Proton Beam Radiotherapy intervention 2: Sorafenib
Intervention descriptions: intervention 1: Fifteen consecutive sessions intervention 2: 400 mg po bid

Protocol document: