Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 32
Healthy volunteers: yes

Brief summary:
Part I:

To investigate whether and to what extent donepezil affects single dose pharmacokinetics of BI 409306

Part II:

To investigate whether and to what extent BI 409306 affects the single dose pharmacokinetics of donepezil

Detailed description:

Arms:
arm 1: Subjects received treatment in a fixed sequence. First BI 409306 as reference treatment (R1)), then BI 409306 + donepezil as test treatment (T1)). arm 2: Subjects received first the reference treatment (R2) followed by a washout period, followed by the test treatment (T2). arm 3: Subjects received first the test treatment 2 (T2) followed by a washout period, followed by the reference treatment 2 (R2)).

Interventions: intervention 1: BI 409306 intervention 2: Donepezil
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: