Conditions: Exercise Training
Keywords: interval training hyperbaric oxygen VO2 max altitude exercise performance mitochondrial oxidative capacity mitochondrial biogenesis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 25
Healthy volunteers: yes

Brief summary:
This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric environment for exercise performance at altitude. Subjects will complete a short, high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after this training phase, all subjects will be tested for maximum aerobic capacity at a simulated high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of mitochondrial oxidative capacity in a skeletal muscle biopsy.

A group of individuals of similar characteristics completing this training program in a normoxic-normobaric environment will serve as a control.

Detailed description:

Arms:
arm 1: Hyperoxic hyperbaric interval exercise training Six sessions of 30 min.of High-intensity interval training completed on a 3-times a week basis at 1.4 ATA of oxygen in a hyperbaric chamber. arm 2: Normoxic, normobaric, interval exercise training Six sessions of 30 min.of High-intensity interval training completed on a 3-times a week basis.

Interventions: intervention 1: Hyperoxic hyperbaric interval exercise training intervention 2: Normoxic, normobaric, interval exercise training intervention 3: Oxygen
Intervention descriptions: intervention 1: Six 30-min high-intensity interval training sessions completed 3-times a week while at 1.4 ATA of oxygen in a hyperbaric chamber. intervention 2: Six 30-min high-intensity interval training sessions completed 3-times a week. intervention 3: Used in Hyperoxic hyperbaric interval exercise training intervention

Protocol document: