Conditions: Thyroid Neoplasm Goiter
Keywords: Ropivacaine Epinephrine Endoscopy Robotics Thyroidectomy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 148
Healthy volunteers: yes

Brief summary:
To assess the pain relief and the hemodynamic stability of ropivacaine with epinephrine in BABA endoscopic and robotic thyroidectomy.

Detailed description:
Diluted ropivacaine with epinephrine is injected into the subcutaneous space to relieve pain and reduce bleeding during procedures. The synergistic effect of ropivacaine with epinephrine can contribute to patients' welfare, such as relieving pain and structuring the hemodynamic stability.

Arms:
arm 1: 100cc normal saline is injected into the subcutaneous layer for the initial flap dissection. arm 2: 1 mg/mL 1cc epinephrine is diluted in 100cc normal saline and then 7.5 mg/mL 30cc ropivacaine is diluted in the same normal saline. The mixture is injected into the subcutaneous layer for the initial flap dissection.

Interventions: intervention 1: Ropivacaine with epinephrine injection intervention 2: Placebo
Intervention descriptions: intervention 1: 1 mg/mL 1cc epinephrine is diluted in 100cc normal saline and then 7.5 mg/mL 30cc ropivacaine is diluted in the same normal saline. The mixture is injected into the subcutaneous layer for the initial flap dissection for the experiment group. intervention 2: 100cc normal saline is injected into the subcutaneous layer for the initial flap dissection for the placebo group.

Protocol document: