Conditions: Abruptio Placentae
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 30
Healthy volunteers: no

Brief summary:
To evaluate the safety and efficacy of magnesium sulfate for preterm suspected abruption.

Detailed description:
We hope to learn if there is a difference in the efficacy of intravenous magnesium sulfate versus intravenous saline infusion in the resolution of vaginal bleeding and contractions in patients with a suspected placental abruption.

Arms:
arm 1: Magnesium Sulfate 4 gram bolus, followed by 2 grams per hour arm 2: Normal Saline 4 gram bolus, followed by 2 grams per hour

Interventions: intervention 1: Magnesium Sulfate intervention 2: Normal Saline
Intervention descriptions: intervention 1: Magnesium Sulfate 4 gram bolus, followed by a maintenance dose at 2 grams per hour. Rate increases up to 4 grams per hour may be administered per physician discretion. intervention 2: Normal Saline infusion of 4 gram bolus, followed by 2 grams per hour with rate increases up to 4 grams per hour per physician discretion.

Protocol document: