Conditions: Hemorrhoid
Keywords: Liposomal Bupivacaine Exparel
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 11
Healthy volunteers: yes

Brief summary:
The purpose of this study is to compare the quality and duration of pain relief after a hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine hcl or control with saline. It is hypothesized that liposomal bupivacaine will provide more effective postoperative pain relief than both bupivacaine hcl and the control.

Detailed description:

Arms:
arm 1: 266mg/20mL Exparel (to be diluted with 10 mL sterile saline to make 30 mL) arm 2: 75mg/30mL 0.25% Bupivacaine HCl with epinephrine arm 3: 30mL Normal Saline

Interventions: intervention 1: Exparel intervention 2: Bupivacaine HCl with Epinephrine intervention 3: Normal Saline
Intervention descriptions: intervention 1: 266 mg/20mL Exparel (to be diluted with 10 mL sterile saline to make 30 mL) intervention 2: 75mg/30mL 0.25% Bupivacaine HCl with epinephrine intervention 3: 30mL Normal Saline

Protocol document: