Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 30
Healthy volunteers: yes

Brief summary:
The purpose of this study is to evaluate the amount of abemaciclib that reaches the blood stream and how long the body takes to get rid of it when given with and without food. In addition, the safety and tolerability of the study drug will be evaluated. Information about any side effects that may occur will also be collected. The study will last about 43 days for each participant, not including screening.

Detailed description:

Arms:
arm 1: Abemaciclib capsules administered once orally in the fed state. arm 2: Abemaciclib capsules administered once orally in the fasted state.

Interventions: intervention 1: Abemaciclib
Intervention descriptions: intervention 1: Administered orally

Protocol document: