Conditions: Injury of Ureter
Keywords: ureteral jet pelvic surgery cystoscopy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 176
Healthy volunteers: yes

Brief summary:
This study evaluates 4 different methods to aid surgeons to visualize ureteral jets on cystoscopy.

Detailed description:
This study proposes to test and compare the surgeon's impression/confidence in identifying ureteral jets using 3 other methods in contrast to standard diagnostic cystoscopy: 1) cystoscopy with Dextrose 10% solution, 2) cystoscopy with phenazopyridine and 3) IV sodium fluorescein 4) standard cystoscopy with saline.

Arms:
arm 1: Infused into the bladder to allow for visualization of bladder walls and urine jets. arm 2: Infused into the bladder to allow for visualization of bladder walls and colored urine jets. arm 3: Will be administered (orally) preoperatively and will be evaluated for its colorization properties during cystoscopy. arm 4: Will be administered (intravenously) prior to the cystoscopy and will be evaluated for its colorization properties during cystoscopy.

Interventions: intervention 1: Normal saline intervention 2: Phenazopyridine intervention 3: Dextrose 10% intervention 4: Sodium Fluorescein
Intervention descriptions: intervention 1: Used to distend the bladder for cystoscopic evaluation intervention 2: Administered orally preoperatively and assessed during cystoscopy intervention 3: Used to distend the bladder for cystoscopic evaluation intervention 4: Administered intravenously and assessed during cystoscopy

Protocol document: