Conditions: Alzheimer Dementia (AD)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 62
Healthy volunteers: no

Brief summary:
Evaluation of the safety and tolerability of a 20 mg once daily dose of memantine compared with 10 mg given twice daily in patients with dementia of Alzheimer's type and MMSE range 5-18.

Detailed description:

Arms:
arm 1: Memantine 20 mg once daily, tablets, orally AND Placebo tablets once daily, orally arm 2: Memantine 10 mg twice daily, tablets, orally AND Placebo tablets twice daily, orally

Interventions: intervention 1: Memantine (once daily) intervention 2: Memantine (twice daily)
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: