Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 44
Healthy volunteers: yes

Brief summary:
This is a study designed to ascertain the effect of PF-04447943 on QT interval in healthy adult subjects. This is conducted as part of standard drug development.

Detailed description:

Arms:
arm 1: 25 mg of PF-04447943 arm 2: 100 mg of PF-04447943 arm 3: Matching placebo for PF-04447943 arm 4: 400 mg of moxifloxacin

Interventions: intervention 1: PF-04447943 intervention 2: Placebo intervention 3: Moxifloxacin
Intervention descriptions: intervention 1: Single oral dose of PF-04447943 administered as an extemporaneously prepared solution intervention 2: Single oral dose of matching placebo for PF-04447943 administered as an extemporaneously prepared solution intervention 3: Single oral dose of moxifloxacin administered as tablet

Protocol document: