Conditions: Peripheral Artery Disease
Keywords: Peripheral artery disease Atherothrombotic events Atherosclerosis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 13885
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare the effects of ticagrelor and clopidogrel in patients with Peripheral Artery Disease.

Detailed description:
A randomized, double-blind, parallel group, multicentre phase IIIb study to compare ticagrelor with clopidogrel treatment on the risk of cardiovascular death, myocardial infarction and ischemic stroke in patients with established Peripheral Artery Disease (EUCLID Examining Use of tiCagreLor In paD)

Arms:
arm 1: Ticagrelor 90 mg bd (and Clopidogrel placebo od) taken orally as tablets arm 2: Clopidogrel 75 mg od (and Ticagrelor placebo bd) taken orally as tablets

Interventions: intervention 1: Ticagrelor intervention 2: Clopidogrel
Intervention descriptions: intervention 1: Ticagrelor 90 mg bd (and Clopidogrel placebo od) taken orally as tablets intervention 2: Clopidogrel 75 mg od (and Ticagrelor placebo bd) taken orally as tablets

Protocol document: