Conditions: Hypercholesterolemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 149
Healthy volunteers: no

Brief summary:
The main purpose of this study is to evaluate the efficacy and safety of the study drug known as evacetrapib when administered in combination with atorvastatin for 12 weeks in Japanese participants with primary hypercholesterolemia.

Detailed description:

Arms:
arm 1: 130 milligrams (mg) evacetrapib and 10 mg atorvastatin administered PO once a day for 12 weeks. arm 2: 10 mg ezetimibe and 10 mg atorvastatin administered PO once a day for 12 weeks as a reference arm. arm 3: Placebo and 10 mg atorvastatin administered PO once a day for 12 weeks.

Interventions: intervention 1: Evacetrapib intervention 2: Ezetimibe intervention 3: Atorvastatin intervention 4: Placebo
Intervention descriptions: intervention 1: Administered orally intervention 2: Administered orally intervention 3: Administered orally intervention 4: Administered orally

Protocol document: