Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 81
Healthy volunteers: no

Brief summary:
This study will consist of multiple ascending oral doses in up to 3 groups, for 29 days.

Detailed description:

Arms:
arm 1: Single loading dose on day 1, followed by single doses on days 8, 15, 22, 29 arm 2: Single loading dose on day 1, followed by a daily dose for 28 days arm 3: Single loading dose on day 1 or days 1-2, followed by a daily dose for 28 days arm 4: Multiple ascending doses matching KQ-791 dose

Interventions: intervention 1: KQ-791 intervention 2: Placebo
Intervention descriptions: intervention 1: Capsules administered orally intervention 2: Capsules administered orally

Protocol document: