Conditions: Cancer Advanced Solid Malignancies
Keywords: Cancer Tumour Solid Malignancies
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 23
Healthy volunteers: no

Brief summary:
The objective of this study will be to investigate the safety and tolerability of olaparib tablet when given orally to Japanese patients with advanced solid malignancies. In addition, the pharmacokinetic profile, MTD (if possible) and efficacy of olaparib will be investigated.

Detailed description:
MTD - maximum tolerated dose

Arms:
arm 1: olaparib tablet

Interventions: intervention 1: olaparib
Intervention descriptions: intervention 1: tablet oral

Protocol document: