Conditions: Healthy Adult Male
Allocation: NON_RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 18
Healthy volunteers: yes

Brief summary:
The ratios of the geometric means of the ODT formulation to those of the reference formulation (conventional tablet) for the bioavailability variables (Cmax, AUCt, and AUC∞ of brexpiprazole (OPC-34712)).

Detailed description:

Arms:
arm 1: OPC-34712 (4 mg) orally disintegrating tablet is administered with water. arm 2: OPC-34712 (4 mg) orally disintegrating tablet is administered without water. arm 3: OPC-34712 (4 mg) conventional tablet is administered with water.

Interventions: intervention 1: OPC-34712
Intervention descriptions: intervention 1: None

Protocol document: