Conditions: Acne Vulgaris
Keywords: acne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1034
Healthy volunteers: no

Brief summary:
To evaluate the efficacy and safety of an approximate 1.5 mg/kg/day dose of oral sarecycline compared to placebo in the treatment of moderate to severe facial acne vulgaris

Detailed description:

Arms:
arm 1: Sarecycline tablets, 1.5 milligram(mg)/kilogram(kg)/day, taken orally once daily for 12 weeks. arm 2: Placebo-matching sarecycline tablets, taken orally once daily for 12 weeks.

Interventions: intervention 1: Sarecycline intervention 2: Placebo
Intervention descriptions: intervention 1: 1.5 mg/kg/day taken orally at the same time each day. intervention 2: Placebo-matching sarecycline tablets, taken orally at the same time each day.

Protocol document: