Conditions: PONV
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1147
Healthy volunteers: no

Brief summary:
A comparison of the efficacy of APD421 and placebo when combined with a standard anti-emetic in the prevention of PONV in patients at high risk of Post-operative Nausea and Vomiting (PONV).

Detailed description:

Arms:
arm 1: Single dose of IV APD421 arm 2: Single dose of IV placebo

Interventions: intervention 1: APD421 intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: