Conditions: Cardiovascular
Allocation: RANDOMIZED | Intervention model: SEQUENTIAL
Enrollment: 48
Healthy volunteers: yes

Brief summary:
A study to assess the safety and tolerability of AMG 529 following single, ascending doses administered subcutaneously (SC) or intravenously (IV) in healthy adults.

Detailed description:

Arms:
arm 1: Participants received a single dose of AMG 529 at ascending dose levels by either subcutaneous or intravenous injection. arm 2: Participants received a single dose of placebo matching to AMG 529 by either subcutaneous or intravenous injection.

Interventions: intervention 1: AMG 529 intervention 2: Placebo
Intervention descriptions: intervention 1: Ascending single doses of AMG 529 by subcutaneous (SC) or intravenous (IV) injection intervention 2: Single doses of matching placebo by SC or IV injection

Protocol document:
Prot_000.pdf: 
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