Conditions: Osteoporosis in Men
Keywords: Osteoporosis in men
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 245
Healthy volunteers: no

Brief summary:
The study is designed to evaluate if treatment with romosozumab once a month for 12 months compared with placebo is effective in increasing bone mineral density (BMD) at the lumbar spine. Additionally, the study will assess the effect of treatment with romosozumab for 12 months compared with placebo on BMD at the femoral neck and total hip.

Detailed description:

Arms:
arm 1: Participants received 210 mg romosozumab administered by subcutaneous injection once a month for 12 months. arm 2: Participants received placebo subcutaneous injections once a month for 12 months.

Interventions: intervention 1: Romosozumab intervention 2: Placebo
Intervention descriptions: intervention 1: Administered by subcutaneous injection once a month. intervention 2: Administered by subcutaneous injection once a month.

Protocol document: