Conditions: Glaucoma, Neovascular
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 54
Healthy volunteers: no

Brief summary:
To assess the efficacy and safety of the administration of aflibercept by intravitreal injection in comparison to sham to control intraocular pressure in patients with neovascular glaucoma.

Detailed description:

Arms:
arm 1: Aflibercept 2 mg Intravitreal (IVT) injection group arm 2: Sham injection group

Interventions: intervention 1: Aflibercept (Eylea, BAY 86-5321) intervention 2: Sham Injection
Intervention descriptions: intervention 1: After the first aflibercept IVT injection on Day 1, subjects may receive sham injection at Week 1, and aflibercept injection at Week 5 and/or Week 9 if the re-treatment criteria are met. intervention 2: After the first sham injection on Day 1, subjects may receive aflibercept IVT injection at Week 1, Week 5 and/or Week 9 if re-treatment criteria are met.

Protocol document: