Conditions: Smoking Addiction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 218
Healthy volunteers: no

Brief summary:
The study will evaluate the effectiveness of smoking cessation using Varenicline versus placebo. Effectiveness will be measured by the average number of cigarettes smoked per smoking day for up to 36 weeks.

Detailed description:

Arms:
arm 1: Varenicline arm 2: Microcrystal cellulose placebo

Interventions: intervention 1: Placebo intervention 2: Varenicline
Intervention descriptions: intervention 1: 25mg look alike riboflavin tablets to match active study medication. intervention 2: Days 1-3 - .5mg tablet 1xdaily Days 4-7 - .5mg tablet 2xdaily Days 8-84 - 1mg tablet 2xdaily

Protocol document: