Conditions: Community Acquired Pneumonia, Severe
Keywords: CAP Pneumonia Intensive Care Unit Mechanical Ventilation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 25
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine if the drug ticagrelor will be an effective treatment for patients with severe community acquired pneumonia. The primary objective is to reduce all-cause mortality in the ticagrelor group compared to the placebo group.

Detailed description:

Arms:
arm 1: Ticagrelor 180 mg loading dose followed by 90 mg BID for 90 days arm 2: Placebo 180 mg loading dose followed by 90 mg BID for 90 days.

Interventions: intervention 1: Ticagrelor intervention 2: Placebo
Intervention descriptions: intervention 1: Ticagrelor 180 mg loading dose followed by 90 mg BID for 90 days intervention 2: Placebo 180 mg loading dose followed by 90 mg BID for 90 days.

Protocol document: