Conditions: Hepatitis C
Keywords: Chronic Hepatitis C Infection
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 943
Healthy volunteers: no

Brief summary:
The primary objectives of this study are to compare the efficacy, safety, and tolerability of treatment with sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) fixed dose combination (FDC) for 8 weeks with that of SOF/VEL FDC for 12 weeks in direct-acting antiviral-naive participants with chronic hepatitis C virus (HCV) infection.

Detailed description:

Arms:
arm 1: SOF/VEL/VOX tablet for 8 weeks arm 2: SOF/VEL tablet for 12 weeks

Interventions: intervention 1: SOF/VEL/VOX intervention 2: SOF/VEL
Intervention descriptions: intervention 1: 400/100/100 mg tablet administered orally once daily with food intervention 2: 400/100 mg tablet administered orally once daily with or without food

Protocol document: