Conditions: Non-arteritic Ischemic Optic Neuropathy Optic Nerve Injuries
Keywords: Ischemic Optic Neuropathy Traumatic Neuropathy Non Arteritic Ischemic Neuropathy (NAION)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 22
Healthy volunteers: no

Brief summary:
The study objectives are to assess any changes in visual acuity and visual field observed following the administration of RPh201 during an overall treatment period of at least 13 consecutive weeks with an option to extended the treatment phase to another 13 weeks (26 weeks total), and at the follow-up visit at 3 month after end of treatment in patients with optic nerve neuropathy.

Detailed description:

Arms:
arm 1: 3/6 month treatment schedule, consisting of bi-weekly SC administration of the RPh201 arm 2: 3/6 month treatment schedule, consisting of bi-weekly SC administration of the Placebo

Interventions: intervention 1: RPh201 intervention 2: Placebo
Intervention descriptions: intervention 1: SC injection twice a week during 13/26 weeks intervention 2: SC injection twice a week during 13/26 weeks

Protocol document: