Conditions: Molluscum Contagiosum
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 94
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine if cantharidin is a safe and effective treatment for molluscum contagiosum in kids

Detailed description:
This was a double-blind, placebo-controlled trial. Participants were recruited from the Pediatric Dermatology clinic at Montefiore Medical Center. One hundred eligible participants were randomly assigned to receive cantharidin 0.7% topical, cantharidin 0.7% topical with occlusion, placebo, or placebo with occlusion. Treatments were applied at weeks 0 and 3 (blinded phase). At week 6, all participants were treated with open-label, topical cantharidin 0.7% without occlusion every 3 weeks until all lesions resolved (open-label phase).

Arms:
arm 1: Cantharidin 0.7% topical with occlusion arm 2: Cantharidin 0.7% topical without occlusion arm 3: Placebo topical with occlusion arm 4: Placebo topical without occlusion

Interventions: intervention 1: Cantharidin intervention 2: Placebo intervention 3: Gauze occlusion bandage
Intervention descriptions: intervention 1: cantharidin 0.7% topical liquid intervention 2: Placebo topical liquid intervention 3: Gauze occlusion bandage with adhesive tape

Protocol document: