Conditions: Lung Transplantation
Keywords: Lung transplantation everolimus kidney function renal function
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 130
Healthy volunteers: no

Brief summary:
This trial evaluated the efficacy of an everolimus-based quadruple low immunosuppressive regimen versus a standard immunosuppressive regimen concerning kidney function in lung transplant recipients.

Detailed description:

Arms:
arm 1: quadruple immunosuppressive (IS) regimen consisting of everolimus, CNI, MPA and steroids arm 2: centre specific CNI-based triple drug immunosuppression (IS)

Interventions: intervention 1: standard therapy intervention 2: Everolimus
Intervention descriptions: intervention 1: centre specific CNI-based triple drug immunosuppression intervention 2: quadruple immunosuppressive regimen consisting of everolimus, CNI, MPA and steroids

Protocol document: