Conditions: Type-2 Diabetes Mellitus
Keywords: type-2 diabetes mellitus, inadequately controlled Metformin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 117
Healthy volunteers: no

Brief summary:
The purpose of this study was to observe change of HbA1c over time from baseline to month 12. The ultimate goal of this study was to provide a local reference value to the physicians \& patients in the future when they consider initiating Vildagliptin and taking balance between efficacy, compliance, risk factors, convenience and medication cost.

Detailed description:

Arms:
arm 1: Vildagliptin 50mg QD plus stabilized or maximum tolerated dose of Metformin arm 2: Vildagliptin 50mg BID plus stabilized or maximum tolerated dose of Metformin

Interventions: intervention 1: LAF237 (vildagliptin) intervention 2: Metformin
Intervention descriptions: intervention 1: Vildagliptin 50mg capsule intervention 2: Metformin maximum tolerance dose

Protocol document: