Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 26
Healthy volunteers: yes

Brief summary:
This study will evaluate how quickly the body absorbs, breaks down, and gets rid of the different formulations of LY900014. This study will determine how the different formulations, when injected under the skin, will affect the blood sugar levels in the body, and how safe it is.

Detailed description:

Arms:
arm 1: Test formulation B: Single dose of LY900014 formulation administered subcutaneously (SC) in one of five periods arm 2: Test formulation B: Single dose of LY900014 formulation administered SC in one of five periods arm 3: Test formulation C: Single dose of LY900014 formulation administered SC in one of five periods arm 4: Formulation D: Single dose of LY900014 formulation administered SC in one of five periods arm 5: Reference formulation: Single dose of lispro administered SC in one of five periods

Interventions: intervention 1: LY900014 intervention 2: Insulin lispro (Humalog)
Intervention descriptions: intervention 1: Administered subcutaneously (SC) intervention 2: Administered SC

Protocol document: