Conditions: Alopecia Areata
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 40
Healthy volunteers: no

Brief summary:
This clinical trial attempts to investigate the efficacy and safety of LEO 124249 ointment in the treatment of alopecia areata and the molecular disease mechanism and biomarkers.

Detailed description:
The objectives of this clinical trial are to compare the efficacy of twice-daily topical LEO 124249 30 mg/g ointment with LEO 124249 ointment vehicle for 12 weeks in the treatment of hair loss in subjects with alopecia areata, to evaluate the safety of this treatment, to evaluate hair regrowth, to determine subject quality of life, and to explore disease mechanism and its biomarkers.

Arms:
arm 1: LEO 124249 ointment 30 mg/g twice daily arm 2: LEO 124249 ointment vehicle twice daily

Interventions: intervention 1: LEO 124249 intervention 2: Vehicle
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: