Conditions: Chalazion Unspecified Eye, Unspecified Eyelid Chalazion Left Eye, Unspecified Eyelid Chalazion Right Eye, Unspecified Eyelid Chalazion Both Eyes
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 150
Healthy volunteers: no

Brief summary:
An eyelid stye, or chalazion, is the most common eyelid ailment, and is caused by the blockage of one of the oil secreting glands of the eyelid (meibomian glands). This leads to a typically painful, swollen, and red eyelid bump that lasts from days to weeks and months. The chalazion may cause tearing, pressure on the cornea, and irritation, all of which contribute to its morbidity. There are many anecdotal first line treatments for this condition, including warm compresses to the eyelid, topical antibiotics, topical steroids, topical combination antibiotic/steroid, and oral antibiotics. There have been no clinical trials to compare the efficacy of any of these conservative treatments. We wish to determine the most effective conservative medical treatment for chalazia.

Detailed description:

Arms:
arm 1: "Hot Compress" arm 2: "Hot Compress", "Tobrex Drops", "Tobrex Ointment" arm 3: "Hot Compress", "Tobradex Drops", "Tobradex Ointment"

Interventions: intervention 1: Hot Compress plus Tobramycin Drops and Ointment intervention 2: Hot compress plus Tobramycin/Dexamethasone Drops and Ointment intervention 3: Hot Compresses
Intervention descriptions: intervention 1: In addition to hot compress, Tobramycin drops will be given to the affected eye 3x/day, and Tobramycin ointment will be given at night before bed. intervention 2: In addition to hot compress, Tobramycin/Dexamethasone drops will be given to the affected eye 3x/day, and Tobramycin/Dexamethasone ointment will be given at night before bed. intervention 3: Hot compresses 3x/day to eyelids

Protocol document: