Conditions: Chronic Hepatitis C(CHC)
Keywords: Feron
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 74
Healthy volunteers: no

Brief summary:
This study will evaluate the efficacy and safety of MP-424 with IFN beta and RBV in patients with genotype 1/2 hepatitis C, who are treatment-naïve or have received its treatment before.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: MP-424 intervention 2: RBV(24 weeks) intervention 3: IFN beta(24 weeks) intervention 4: RBV(48 weeks) intervention 5: IFN beta(48 weeks)
Intervention descriptions: intervention 1: MP-424: 750mg every 8 hours (q8h) for 12 weeks intervention 2: RBV: 600 - 1000mg/day based on body weight for 24 weeks intervention 3: IFN beta: 600 MIU/day,6 days/week for initial 4 weeks following to 3 days/week for 24 weeks intervention 4: RBV: 600 - 1000mg/day based on body weight for 48 weeks intervention 5: IFN beta: 600 MIU/day,6 days/week for initial 4 weeks following to 3 days/week for 48 weeks

Protocol document: