Conditions: Coronary Artery Disease Coronary Heart Disease Dyslipidemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 682
Healthy volunteers: no

Brief summary:
The primary purpose of this study is to test the effect and safety of once daily ABT-335 on the thickness of the lining of the carotid artery (a blood vessel to the brain) in patients with abnormal blood lipids who have optimal levels of low density lipoprotein cholesterol ("bad cholesterol") after taking atorvastatin.

Detailed description:

Arms:
arm 1: ABT-335 (135 mg) and atorvastatin (up to 40 mg) once daily for 2 years. arm 2: Placebo and atorvastatin (up to 40 mg) once daily for 2 years.

Interventions: intervention 1: ABT-335 intervention 2: Placebo intervention 3: Atorvastatin
Intervention descriptions: intervention 1: Capsule intervention 2: Capsule intervention 3: Capsule

Protocol document: