Conditions: Hematoma, Subdural, Chronic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 47
Healthy volunteers: no

Brief summary:
The project aims at investigating if treatment with the Angiotensin Converting Enzyme inhibitor Coversyl (perindopril) for 3 months after surgery for chronic subdural hematoma will decrease the risc of recurrence.

Detailed description:
Previous studies have indicated that treatment with ACE inhibitors can reduce the risk of recurrence of CSDH after surgical evacuation. This randomized clinical trial was designed to investigate this

Arms:
arm 1: patients randomized to this arm will be treated with ACE inhibitors after surgery arm 2: patients randomized to this arm will be treated with placebo after surgery

Interventions: intervention 1: Perindopril intervention 2: Placebo
Intervention descriptions: intervention 1: 2,5 mg daily for 3 months intervention 2: Placebo dayli for 3 months

Protocol document: