Conditions: Duchenne Muscular Dystrophy
Allocation: NON_RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 53
Healthy volunteers: no

Brief summary:
This is an interventional study on Duchenne muscular dystrophy patients who will be receiving sedation for a muscle biopsy as part of another study.

Detailed description:

Arms:
arm 1: Patients receive a loading dose of dexmedetomidine 1 mcg/kg followed by a continuous infusion of 1 mcg/kg/hr. arm 2: Patients receive a loading dose of dexmedetomidine 0.5 mcg/kg followed by a continuous infusion of 0.5 mcg/kg/hr.

Interventions: intervention 1: Ketamine intervention 2: Dexmedetomidine
Intervention descriptions: intervention 1: 1 mg/kg IV, additional doses of 0.5 mg/kg as needed intervention 2: 0.5 mcg/kg/hr IV

Protocol document: