Conditions: Prostate Cancer
Keywords: Locally advanced or metastatic Prostate Cancer
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 339
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effect of an initial hormonal treatment gonadotrophin-releasing hormone (GnRH Agonist) on 2 biomarkers (PCA3 and TMPRSS2-ERG), in patients with histologically confirmed and advanced stages of prostate cancer. Their characteristics, according to risk factors such as PSA and Gleason score will be determined at baseline and 1, 3 and 6 month post-treatment.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Triptorelin (Decapeptyl®)
Intervention descriptions: intervention 1: One intramuscular injection of triptorelin (Decapeptyl®) 22.5mg performed once all baseline procedures and assessments have been completed.

Protocol document: