Conditions: Hepatitis C
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 49
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine whether multiple doses of darunavir/ritonavir or lopinavir/ritonavir affect the pharmacokinetics of daclatasvir in healthy participants.

Detailed description:

Arms:
arm 1: Treatment A: Daclatasvir oral tablet on specific days

Treatment B: Daclatasvir tablet and Darunavir Tablet/Ritonavir capsule orally on specific days arm 2: Treatment C: Daclatasvir oral tablet on specific days

Treatment D: Daclatasvir tablet and Lopinavir/Ritonavir tablet orally on specific days

Interventions: intervention 1: Daclatasvir intervention 2: Darunavir intervention 3: Ritonavir intervention 4: Lopinavir/Ritonavir
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None intervention 4: None

Protocol document: