Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 278
Healthy volunteers: no

Brief summary:
The objective of the current study is to investigate the efficacy, safety and tolerability of Linagliptin (5 mg once daily) compared to placebo given for 24 weeks as add on therapy to metformin in combination with pioglitazone in patients with type 2 diabetes mellitus with insufficient glycaemic control.

Detailed description:

Arms:
arm 1: Linagliptin tablets once daily arm 2: Placebo tablets once daily

Interventions: intervention 1: Placebo intervention 2: Linagliptin
Intervention descriptions: intervention 1: Placebo matching linagliptin tablets once daily intervention 2: Linagliptin tablets once daily

Protocol document: