Conditions: Psoriasis
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 145
Healthy volunteers: yes

Brief summary:
A healthy subject, 2-way cross-over study to evaluate the bioequivalence of a single dose of Brodalumab vs. two doses of Brodalumab

Detailed description:
A healthy subject, 2-way cross-over study to evaluate the bioequivalence of a single 1.5mL dose of Brodalumab (140mg/mL) vs. two doses (1.0mL + 0.5mL) of Brodalumab (140mg/mL)

Arms:
arm 1: A single 210 mg subcutaneous (SC) dose of Brodalumab administered using a single 1.5mL pre-filled syringe injection arm 2: A single 210 mg subcutaneous (SC) dose of Brodalumab administered using 2 (1.0mL + 0.5mL) pre-filled syringe injections

Interventions: intervention 1: Brodalumab
Intervention descriptions: intervention 1: Brodalumab is a large molecule for the treatment of inflammatory diseases

Protocol document: