Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Keywords: COPD
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 87
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the pharmacodynamics (bronchodilation) of single doses of inhaled LAS100977 in COPD patients.

Detailed description:

Arms:
arm 1: Single dose, double blind treatment period arm 2: Single dose, double blind treatment period arm 3: Single dose, double blind treatment period arm 4: Single dose, double blind treatment period arm 5: Single dose, double blind treatment period arm 6: Single dose, double blind treatment period

Interventions: intervention 1: LAS100977 intervention 2: LAS100977 intervention 3: LAS100977 intervention 4: LAS100977 intervention 5: Reference intervention 6: Placebo
Intervention descriptions: intervention 1: Dry powder inhalation,Once daily, single dose intervention 2: Dry powder inhalation,Once daily, single dose intervention 3: Dry powder inhalation,Once daily, single dose intervention 4: Dry powder inhalation,Once daily, single dose intervention 5: Dry powder inhalation (capsule),single dose intervention 6: Dry powder inhalation or Dry powder inhalation (capsule),Once daily, single dose

Protocol document: