Conditions: Dermatitis, Atopic
Keywords: atopic dermatitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 86
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the safety and efficacy of AN2728 Topical Ointment, 2% and 0.5%, administered once a day (QD) or twice a day (BID), in the treatment of adolescents with atopic dermatitis (AD)

Detailed description:

Arms:
arm 1: AN2728 Topical Ointment, 2% applied once daily for 29 days to a target lesion, and AN2728 Topical Ointment, 0.5% applied once daily for 29 days to a target lesion

Treatments will be randomly assigned to target lesions A and B. arm 2: AN2728 Topical Ointment, 2% applied twice daily for 29 days to a target lesion, and AN2728 Topical Ointment, 0.5% applied twice daily for 29 days to a target lesion.

Treatments will be randomly assigned to target lesions A and B.

Interventions: intervention 1: AN2728 Topical Ointment, 2% QD intervention 2: AN2728 Topical Ointment, 0.5% QD intervention 3: AN2728 Topical Ointment, 2% BID intervention 4: AN2728 Topical Ointment, 0.5% BID
Intervention descriptions: intervention 1: AN2728 Topical Ointment, 2% QD intervention 2: AN2728 Topical Ointment, 0.5% QD intervention 3: AN2728 Topical Ointment, 2% BID intervention 4: AN2728 Topical Ointment, 0.5% BID

Protocol document: