Conditions: Parkinson's Disease
Keywords: Parkinson's Disease Fatigue
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 30
Healthy volunteers: no

Brief summary:
The purpose of the research study is to determine if rasagiline is an effective treatment for fatigue in patients with Parkinson's disease (PD).

Detailed description:
Despite the fact that fatigue affects 40-50% of all patients with PD and is a leading cause of disability, we currently do not have any effective treatments for this symptom. Rasagiline is a well-tolerated and effective treatment for the motor symptoms of PD. Rasagiline is a MAO-B inhibitor that may decrease the breakdown of dopamine. Many patients report an improvement in their energy levels when on this medication. A proven treatment for PD fatigue would significantly improve the quality of life for numerous patients and their caregivers.

Arms:
arm 1: Placebo tablet, 1 per day, duration is approximately 12 weeks. arm 2: Rasagiline tablet, 1 mg, 1 per day, duration is approximately 12 weeks.

Interventions: intervention 1: Rasagiline intervention 2: Placebo
Intervention descriptions: intervention 1: Comparison of Rasagiline versus placebo.

Rasagiline tablet, 1 mg, 1 per day, duration is approximately 12 weeks. intervention 2: Comparison of Rasagiline versus placebo. Placebo tablet, 1 per day, duration is approximately 12 weeks.

Protocol document: