Conditions: Fallopian Tube Cancer Ovarian Cancer Malignant Tumor of Peritoneum
Keywords: recurrent ovarian epithelial cancer recurrent primary peritoneal cavity cancer recurrent fallopian tube cancer
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 45
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effectiveness of the combination of Avastin and Docetaxel in the treatment of women with platinum sensitive recurrent epithelial ovarian cancer within 12 months of platinum chemotherapy.

Detailed description:

Arms:
arm 1: Combination Therapy: Immunotherapy (Avastin) and Chemotherapy (Docetaxel) as outlined in Intervention descriptions. Avastin: 15 mg/kg, In 100 ml normal saline (NS) IV infusion over 90 +/- 15 minutes, Day 1, every 21 day cycle. Docetaxel: 40 mg/m\^2, In 250 ml 5% dextrose in pure water (D5W) or NS IV infusion over 1 hour in a non-pvc container and through a polyethylene-lined set, Day 1, 8, every 21 day cycle. Response assessment every 3 cycles (9 weeks).

Interventions: intervention 1: Avastin intervention 2: Docetaxel
Intervention descriptions: intervention 1: Day 1, every 21 day cycle intervention 2: Day 1, 8, every 21 day cycle

Protocol document: