Conditions: Leukaemia, Lymphocytic, Chronic
Keywords: Maintenance Retreatment Chronic lymphocytic leukemia B-Cell Chronic Lymphocytic Leukemia Ofatumumab
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 29
Healthy volunteers: no

Brief summary:
The purpose of the trial is to investigate the efficacy and safety of ofatumumab retreatment and maintenance in patients with chronic lymphocytic leukemia who have previously responded or had disease stabilization after ofatumumab in an ongoing trial (Hx-CD20-406).

Detailed description:

Arms:
arm 1: Eight once weekly infusions (1 x 300 mg + 7 x 2000 mg), then 2000 mg once monthly for two years

Interventions: intervention 1: Ofatumumab
Intervention descriptions: intervention 1: Eight once weekly infusions (1 x 300 mg + 7 x 2000 mg), then 2000 mg once monthly for two years

Protocol document: