Conditions: Osteoarthritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 58
Healthy volunteers: yes

Brief summary:
* To investigate the safety and tolerability of BI 1026706 in male and female healthy subjects and osteoarthritis (OA) patients following oral administration of repeated rising doses
* To explore the pharmacokinetics after multiple rising doses of BI 1026706 in male and female healthy subjects and OA patients
* The assessment of pharmacodynamics in OA patients

Detailed description:

Arms:
arm 1: Multiple Rising Doses Placebo to BI 1026706 arm 2: Multiple Rising Doses BI 1026706

Interventions: intervention 1: BI 1026706 intervention 2: Placebo to BI 1026706
Intervention descriptions: intervention 1: Multiple Rising Doses (oral solution, tablet) intervention 2: Multiple Rising Doses (oral solution / tablet, identical to active treatment)

Protocol document: