Conditions: Diabetic Ketoacidosis
Keywords: Pediatrics Diabetes Emergency Care Endocrinology Critical Care
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 75
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the effects of the addition of insulin glargine during the early phase of moderate to severe Diabetic Ketoacidosis (DKA) in children.

The investigators hypothesize that the addition of insulin glargine during the early phase of management of DKA will accelerate acidosis correction, decrease the length of insulin infusion, and decrease the total intensive care unit time in children admitted to the ICU.

Detailed description:

Arms:
arm 1: 0.3u/kg of glargine, subcutaneously, once arm 2: 0.3u/kg of saline, subcutaneously, once

Interventions: intervention 1: glargine intervention 2: saline
Intervention descriptions: intervention 1: 0.3u/kg of glargine, subcutaneously, once intervention 2: 0.3u/kg of saline, subcutaneously, once

Protocol document: