Conditions: Myopia Refractive Error
Keywords: Contact lens Lens care
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 94
Healthy volunteers: yes

Brief summary:
The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.

Detailed description:
An estimated 40 million people in the United States wear contact lenses, with approximately 38 million soft lens wearers and 2 million rigid gas permeable lens wearers. The ocular surface has been shown to respond to the introduction of foreign materials with upregulation of proinflammatory mediators, leading to an increase in inflammation. The corneal can show a foreign body immune response to contact lenses. The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across the three lens care regimens in new contact lens wearers.

Arms:
arm 1: 33 participants will be assigned to use this lens care regimen during the six-week assessment period arm 2: 33 participants will be assigned to use this lens care regimen during the six-week assessment period arm 3: 33 participants will be assigned to use this lens care regimen during the six-week assessment period

Interventions: intervention 1: ReNu MultiPlus® MultiPurpose Solution intervention 2: OPTI-FREE® RepleniSH® intervention 3: Clear Care®
Intervention descriptions: intervention 1: Contact lens care regimen intervention 2: Contact Lens care regimen intervention 3: Contact lens care regimen

Protocol document: