Conditions: Anorexia and Bulimia Nervosa
Keywords: Anorexia, Bulimia, Anxiety, Exposure
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 47
Healthy volunteers: no

Brief summary:
This is a pilot study investigating if cycloserine (DCS; a learning enhancement medication) augments exposure therapy for food anxiety in patients with anorexia and bulimia nervosa. The investigators expect that (a) exposure therapy will reduce anxiety (b) anxiety will be reduced more in the DCS relative to placebo condition (c) participants in the DCS condition will have a greater increase in Body Mass Index.

Detailed description:
This study investigated if DCS vs placebo augmented food exposure in individuals with eating disorders.

Arms:
arm 1: 250 mg DCS (setraline) versus placebo plus exposure arm 2: Placebo group plus exposure

Interventions: intervention 1: Placebo vs Setraline intervention 2: Setraline
Intervention descriptions: intervention 1: Placebo intervention 2: 250mg DCS

Protocol document: