Conditions: Healthy Volunteers
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: yes

Brief summary:
The aim of this two-period study is to compare how much of the study drug gets into the blood stream when it is given as a single oral dose and when it is given as a single oral dose in combination with rifampin (a Food and Drug Administration \[FDA\] approved antibiotic that is used to treat tuberculosis, a bacterial infection that mainly affects the lungs, and other infections). Each participant will complete both study periods.

The study will last about 34 days. Screening is required within 28 days before study drug is given.

Detailed description:

Arms:
arm 1: Single oral dose of LY2835219 arm 2: Single oral dose of LY2835219 with rifampin orally, once daily for 14 days

Interventions: intervention 1: LY2835219 intervention 2: Rifampin
Intervention descriptions: intervention 1: Administered orally intervention 2: Administered orally

Protocol document: