Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Acute exacerbation of Chronic obstructive pulmonary disease Acute Exacerbation Chronic obstructive pulmonary disease(COPD) Zabofloxacin Moxifloxacin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 345
Healthy volunteers: no

Brief summary:
The purpose of this study is to Evaluate the Efficacy and Safety Profiles of oral multiple dose of Zabofloxacin Tablet 400 mg.

Detailed description:
A Phase 3, Multicenter, Double Blind, Active Controlled, Randomized Study to Evaluate the Efficacy and Safety of Zabofloxacin for Patients with acute bacterial exacerbation of Chronic obstructive pulmonary disease.

Arms:
arm 1: Zabofloxacin 367mg tablet P.O. once daily for 5days and then Placebo P.O. once daily for 2days arm 2: Moxifloxacin 400mg tablet P.O. once daily for 7days

Interventions: intervention 1: Zabofloxacin intervention 2: Moxifloxacin
Intervention descriptions: intervention 1: Zabofloxacin 367mg tablet P.O. once daily for 5days and then Placebo P.O. once daily for 2days intervention 2: Moxifloxacin 400mg tablet P.O. once daily for 7days

Protocol document: