Conditions: Symptomatic Vitreomacular Adhesion
Keywords: Vitreomacular Adhesion Vitreomacular Traction Vitreomacular Traction Syndrome Vitrectomy Central Visual Field Defect Blind Spot Intravitreal Injection Macula Retina Decreased Visual Acuity Visual Complaint SD-OCT Macular Hole
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 251
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the superiority regarding vitreomacular adhesion (VMA) resolution of a single intravitreal injection of A01016 (Ocriplasmin) compared to sham-injection in subjects with symptomatic VMA.

Detailed description:

Arms:
arm 1: Ocriplasmin administered as a single intravitreal injection to the study eye at baseline arm 2: Single sham injection to the study eye at baseline

Interventions: intervention 1: Ocriplasmin intervention 2: Sham injection
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: