Conditions: Postoperative Pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 240
Healthy volunteers: no

Brief summary:
The efficacy and safety of oxycodone capsules compared with morphine tablets in hospitalized patients with moderate to severe pain following surgery.

Detailed description:
To evaluate the efficacy and safety of oxycodone immediate-release capsules compared with morphine immediate-release tablets in hospitalized patients with moderate to severe pain following surgery.

Arms:
arm 1: To determine the efficacy and safety of OxyNorm Capsules. arm 2: To determine the efficacy and safety of Morphine tablet.

Interventions: intervention 1: OxyNorm Capsules intervention 2: Morphine tablet
Intervention descriptions: intervention 1: dosage:5mg,l0mg and 20mg dosage form:capsule frequency:every 6h, duration:24 hours intervention 2: dosage: 10mg and 20mg; dosage form: tablet; frequency: every 6h; duration: 24 hours.

Protocol document: