Conditions: Reduction in Hypertrophic Skin Scarring
Keywords: Skin scarring cicatrix breast scar
Allocation: RANDOMIZED | Intervention model: 
Enrollment: 68
Healthy volunteers: no

Brief summary:
The study will investigate the efficacy of various doses and regimens of EXC 001 in reducing skin scarring in subjects undergoing revision of scars from prior surgery. The study will also evaluate the safety and tolerability of EXC 001 and placebo.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: EXC 001 intervention 2: EXC 001 intervention 3: EXC 001 intervention 4: EXC 001
Intervention descriptions: intervention 1: Single-dose administered by injection four different times intervention 2: Single reduced dose compared to Group 1 administered by injection at the same four time periods as Group 1 intervention 3: Single reduced dose compared to Groups 1 and 2 administered by injection at the same four time periods as Groups 1 and 2 intervention 4: Same sinlge dose as Group 1 administered by injection at the same four time periods as Groups 1, 2, and 3

Protocol document: