Conditions: Blood Pressure Anxiety
Keywords: Dexmedetomidine Spinal anesthesia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 74
Healthy volunteers: no

Brief summary:
Patients were randomized into two groups, A group and B group. A group and B group patients are injected intravenous dexmedetomidine after intrathecal injection (IT) of heavy bupivacaine and injected intravenous dexmedetomidine before IT of heavy bupivacaine, respectively.

The investigators will compare of hemodynamics and patient's comfortability between two groups.

Detailed description:
A and B group patients will intravenous inject dexmedetomidine 1mcg/kg for 10 minute loading infusion and 0.2mcg/kg/hr for continuous infusion. A group receive intravenous dexmedetomidine after procedure, and B group receive intravenous dexmedetomidine before procedure. Both group patients will hydrate 6 ml/kg crystalloid solution and will evaluated patient's anxiety and comfortability perioperative period. Vital signs will record 5 minutes interval at operating room and post-anesthetic care units.

Arms:
arm 1: IV dexmedetomidine infusion before intrathecal injection of heavy bupivacaine arm 2: IV dexmedetomidine infusion after intrathecal injection of heavy bupivacaine

Interventions: intervention 1: Dexmedetomidine intervention 2: Dexmedetomidine with heavy bupivacaine
Intervention descriptions: intervention 1: Dexmedetomidine infusion before intrathecal injection of heavy bupivacaine intervention 2: Dexmedetomidine infusion after IT of heavy bupivacaine

Protocol document: