Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 36
Healthy volunteers: yes

Brief summary:
Evaluation of potential ticagrelor effects on dabigatran exposure and evaluation of two new pharmacodynamic methods

Detailed description:

Arms:
arm 1: low dose dabigatran + high dose ticagrelor arm 2: high dose ticagrelor arm 3: medium dose dabigatran arm 4: low dose dabigatran

Interventions: intervention 1: dabigatran etexilate intervention 2: Ticagrelor intervention 3: Ticagrelor intervention 4: dabigatran etexilate intervention 5: dabigatran etexilate
Intervention descriptions: intervention 1: medium dose dabigatran intervention 2: high dose ticagrelor intervention 3: high dose ticagrelor intervention 4: low dose dabigatran intervention 5: medium dose dabigatran

Protocol document: