Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 20
Healthy volunteers: yes

Brief summary:
The primary objective of this trial is to investigate the relative bioavailability of a single oral dose of BI 113608 without and with ketoconazole and voriconazole at steady state. The assessment of safety and tolerability of BI 113608 administered alone and upon co-administration will be an additional objective of this trial.

Detailed description:

Arms:
arm 1: tablets with 240 ml water arm 2: tablets with 240 ml water arm 3: tablets with 240 ml water

Interventions: intervention 1: BI 113608 intervention 2: BI 113608 intervention 3: BI 113608 intervention 4: Ketoconazole intervention 5: Voriconazole
Intervention descriptions: intervention 1: tablet intervention 2: tablet intervention 3: tablet intervention 4: tablet intervention 5: tablet

Protocol document: