Conditions: Oral Hygiene
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 160
Healthy volunteers: yes

Brief summary:
The aim of this study is to compare the stain effect on teeth of twice daily brushing with a 67% sodium bicarbonate containing toothpaste versus standard toothpaste (not containing sodium bicarbonate) for six weeks whilst using a chlorhexidine digluconate 0.2% mouthwash.

Detailed description:

Arms:
arm 1: Marketed Sodium bicarbonate toothpaste containing 1400 parts per million (ppm) fluoride as Sodium fluoride (NaF) arm 2: Non-sodium bicarbonate toothpaste containing 1450ppm fluoride as NaF arm 3: 0.2% w/v Chlorhexidine digluconate mouthwash for rinsing post-brushing with study toothpastes

Interventions: intervention 1: Sodium bicarbonate/ Sodium Fluoride intervention 2: Sodium fluoride intervention 3: Chlorhexidine digluconate
Intervention descriptions: intervention 1: Toothpaste containing sodium bicarbonate and sodium fluoride as cosmetic intervention 2: Toothpaste containing sodium fluoride as cosmetic intervention 3: Mouthwash containing chlorhexidine digluconate

Protocol document: