Conditions: Schizophrenia
Keywords: receptors nicotinic
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 10
Healthy volunteers: yes

Brief summary:
The study determines if a new preparation of a drug designed to treat schizophrenia is more slowly released into the body.

Detailed description:
3-2,4 dimethoxybenzylidene will be compounded with a methyallose compound in doses of 150 and 300 mg. The capsules will be administered singly and eventually bid to determine if sustained blood levels comparable to steady state blood levels seen in previous studies can be determined. Safety and EEG effects will be measured.

Arms:
arm 1: This single arm examines the pharmaco-kinetics of the release of 3-2,4 dimethoxy-benzilidene anabaseine in a hypomellose sustained release formulation.

Interventions: intervention 1: Pharmacokinetic
Intervention descriptions: intervention 1: Subject receives 150 mg of compound formulated with hypomellose and Pharmcokinetics is determined

Protocol document: