Conditions: Diabetes Mellitus Heart Failure
Keywords: CE-MRI - Contrast-enhanced magnetic resonance imaging DM - Diabetes mellitus EKG - Echocardiography HFPEF - Heart failure preserved left ventricular ejection fraction LVEF - Left Ventricular Ejection Fraction
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 4
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the results of 99mTc maraciclatide scintigraphy in diabetic subjects with HFPEF. A maximum of 20 subjects with Diabetes Mellitus (DM) and Heart Failure With Preserved Left Ventricular Ejection Fraction (HFPEF) will be enrolled and imaged with 99mTc maraciclatide. In addition, a maximum of 10 subjects with DM and diastolic dysfunction but no diagnosis of heart failure (HF) will be enrolled and imaged with 99mTc-maraciclatide.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Tc99m-Maraciclatide
Intervention descriptions: intervention 1: Freeze-dried powder Kit for the preparation of Maraciclatide (99mTc) Injection

Protocol document: