Conditions: Osteoarthritis of the Knee
Keywords: Validation of the WOMAC in Chinese subjects with osteoarthritis of the knee
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 408
Healthy volunteers: yes

Brief summary:
This study is to validate the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) tool in mainland Chinese patients with osteoarthritis of the knee . This study will also evaluate the effects of Mobic versus placebo on reducing the symptoms of osteoarthritis in this population.

Detailed description:
To validate culturally the WOMAC tool in mainland China and observe the different response of meloxicam and placebo in a patient population with osteoarthritis of the knee

Arms:
arm 1: None arm 2: 2 Placebo capsules once a day for 12 weeks

Interventions: intervention 1: Meloxicam intervention 2: Placebo
Intervention descriptions: intervention 1: 7.5mg x2 once a day for 12 weeks intervention 2: Study subjects will be randomized to two treatment groups: one with Meloxicam 7.5 mgx2 once a day and another one with placebo. The duration of the interventional treatment is 12 weeks.

Protocol document: