Conditions: Hypertrophic Scars Resulting From Prior Breast Scar Revision Surgery
Keywords: Phase 2 open-label safety hypertrophic scar revision surgery
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 10
Healthy volunteers: no

Brief summary:
Study is a multicenter, two-part, open-label phase II study in adults, evaluating the safety and long-term efficacy of PF-06473871 one year after surgical revision and treatment with PF-06473871.

Detailed description:

Arms:
arm 1: The number of doses each subject receives will be consistent with number received in protocol B5301001 (Group 1 = 4 doses). arm 2: The number of doses each subject receives will be consistent with number received in protocol B5301001 (Group 2 = 3 doses).

Interventions: intervention 1: PF-06473871 intervention 2: PF-06473871
Intervention descriptions: intervention 1: Subjects who previously were randomized in B5301001 study will go under a second revision surgery followed by 4 administration of PF-06473871. intervention 2: Subjects who previously were randomized in B5301001 study will go under a second revision surgery followed by 3 administration of PF-06473871.

Protocol document: