Conditions: Vitamin D Deficiency Primary Hyperparathyroidism Hypercalcemia
Keywords: Vitamin D Primary hyperparathyroidism hypercalcemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 46
Healthy volunteers: no

Brief summary:
The primary aim of the study is to assess whether 6-months of vitamin D supplements can decrease PTH compared with placebo treatment in primary hyperparathyroidism.

Detailed description:
The study investigates effects and safety of six months of vitamin D supplementation before and after surgery in primary hyperparathyroidism. Effects are assessed as changes in calcium homeostasis, bone metabolism, quality of life, and muscle strength and function.

Arms:
arm 1: Cholecalciferol 1400 IU, 2 tablets once daily in 52 weeks arm 2: Placebo, two tablets daily in 52 weeks.

Interventions: intervention 1: Cholecalciferol
Intervention descriptions: intervention 1: 2800 IE daily in 52 weeks

Protocol document: