Conditions: Nicotine Dependence
Keywords: smoking adolescents contingency management nicotine replacement therapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 154
Healthy volunteers: no

Brief summary:
The purpose of this study is to examine the the efficacy of adjunctive nicotine replacement therapy when used in combination with the contingency management (CM) + cognitive behavioral therapy intervention. Subjects will be randomly assigned to receive either a nicotine transdermal patch or a placebo patch as well as being randomly assigned to receive either CM or no CM; all subjects will receive cognitive behavioral therapy. We hypothesize that that subjects receiving both active nicotine patch and CM will have higher rates of abstinence from tobacco than subjects in the other groups.

Detailed description:

Arms:
arm 1: Subjects in this group will receive Contingency Management and active nicotine patch arm 2: Subjects in this group will receive active nicotine patch without contingency management for abstinence arm 3: Subjects in this group will receive a placebo transdermal patch and contingency management arm 4: Subjects in this group will receive a placebo patch and will not receive contingency management

Interventions: intervention 1: Cognitive Behavioural Therapy intervention 2: Contingency Management intervention 3: Nicotine Transdermal Patch
Intervention descriptions: intervention 1: Weekly CBT for all subjects intervention 2: incentives given for abstinence based on urine analysis intervention 3: 14mg ir 21mg doses based on weight and #cigs/day

Protocol document: