Conditions: Healthy
Keywords: Comparative Bioavailability lomitapide
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 32
Healthy volunteers: yes

Brief summary:
To compare the relative bioavailability of lomitapide when administered by sprinkling the contents of a 20 mg capsule of lomitapide in applesauce or in mashed banana to a single oral intact capsule dose of 20 mg lomitapide in healthy subjects.

Detailed description:

Arms:
arm 1: Contents of single 20 mg capsule of lomitapide sprinkled in applesauce arm 2: Contents of single 20 mg capsule of lomitapide sprinkled in mashed banana arm 3: Intact capsule of 20 mg lomitapide

Interventions: intervention 1: lomitapide
Intervention descriptions: intervention 1: None

Protocol document: