Conditions: Acute on Chronic Hepatic Failure Acute Liver Failure Liver Cirrhosis Acute Alcoholic Hepatitis
Keywords: Liver Failure Cirrhosis Alcoholic Hepatitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 23
Healthy volunteers: no

Brief summary:
The study will evaluate the pharmacokinetics, pharmacodynamics, safety and preliminary efficacy of IDN-6556 in subjects with cirrhosis of the liver who are hospitalized for more than 24 hours due to acute deterioration of liver function.

Detailed description:

Arms:
arm 1: Dosed twice daily arm 2: Dosed twice daily arm 3: Dosed twice daily arm 4: Dosed twice daily

Interventions: intervention 1: IDN-6556 intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: