Conditions: Pathological Gambling
Keywords: Gambling Addiction
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
The goal of the proposed study is to evaluate the efficacy and safety of tolcapone in pathological gambling.

Detailed description:
The proposed study will consist of 8 weeks of treatment with tolcapone in 10 subjects with pathological gambling. The hypothesis to be tested is that tolcapone will be effective in reducing the urges to gamble in patients with pathological gambling. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Arms:
arm 1: Tolcapone 100-300mg/day

Interventions: intervention 1: Tolcapone
Intervention descriptions: intervention 1: pill, 100-300mg/day for 8 weeks

Protocol document: