Conditions: Lymphoma, Non-Hodgkin Lymphoma Lymphomas: Non-Hodgkin Follicular / Indolent B-Cell Lymphomas: Non-Hodgkin
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 30
Healthy volunteers: no

Brief summary:
To assess the feasibility of using intra-tumoral PF-3512676 in combination with local radiation as a therapy for lowgrade b-cell lymphoma.

Detailed description:

Arms:
arm 1: Patients will be treated with 18 mg PF-3512676 by intratumoral injection on day 2 following local radiotherapy, then weekly for a total of 10 injections over 10 weeks.

Interventions: intervention 1: PF-3512676 intervention 2: Local radiotherapy
Intervention descriptions: intervention 1: 18 mg injection intervention 2: 2 gray (2 Gy) on each of Days 1 and 2

Protocol document: