Conditions: Diabetes Mellitus, Type 2
Keywords: diabetes
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 685
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the safety and efficacy of albiglutide in subjects with type 2 diabetes

Detailed description:

Arms:
arm 1: Metformin + glimepiride + pioglitazone + matching albiglutide placebo arm 2: Metformin + open-label glimepiride + pioglitazone matching placebo + albiglutide arm 3: metformin + open-label glimepiride + pioglitazone placebo + albiglutide placebo

Interventions: intervention 1: placebo to match albiglutide intervention 2: albiglutide intervention 3: metformin intervention 4: glimepiride intervention 5: pioglitazone intervention 6: placebo to match pioglitazone
Intervention descriptions: intervention 1: albiglutide matching placebo weekly subcutaneous injection intervention 2: albiglutide weekly subcutaneous injection intervention 3: metformin intervention 4: glimepiride intervention 5: pioglitazone intervention 6: pioglitazone matching placebo

Protocol document: