Conditions: Chronic Low Back Pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 302
Healthy volunteers: no

Brief summary:
PF-06372865 In Subjects With Chronic Low Back Pain

Detailed description:

Arms:
arm 1: Daily BID dosing for 4 weeks arm 2: Daily BID dosing for 4 weeks arm 3: Daily BID dosing for 4 weeks

Interventions: intervention 1: PF-06372865 intervention 2: Placebo intervention 3: Naproxen
Intervention descriptions: intervention 1: Dose level 1 daily dosing BID for 1 week followed by dose level 2 daily BID for 3 weeks intervention 2: Placebo for PF-06372865 and placebo for naproxen daily intervention 3: 500 mg BID for 4 weeks

Protocol document: