Conditions: Smoking Cessation
Keywords: smoking cessation varenicline smoking cessation treatment
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 60
Healthy volunteers: yes

Brief summary:
The purpose of this study is to explore the use of an prolonged alternative dosing schedule using varenicline for smoking cessation leading to greater quit rates and higher rates of continuous abstinence.

Detailed description:
This pilot study will utilize a two group randomized design. Adult smokers who are motivated to quit smoking will be randomized to one of two treatment groups. Both groups will receive brief support counseling. During a one-week baseline and the 4-week pre-quit period smoking rate, smoking satisfaction, withdrawal, and craving will be assessed on a daily basis.

Arms:
arm 1: drug plus counseling. arm 2: placebo plus counseling

Interventions: intervention 1: varenicline intervention 2: placebo
Intervention descriptions: intervention 1: variable dosing schedule intervention 2: placebo

Protocol document: