Conditions: Alzheimer Disease Cognitive Impairment
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 255
Healthy volunteers: no

Brief summary:
The primary purpose of this study is to determine whether sodium oligo-mannurarate capsule is effective and safe in the treatment of mild to moderate alzheimer' disease, and to determine the best therapeutic dose of sodium oligo-mannurarate capsule.

Detailed description:
Alzheimer's disease is known for placing a great burden on caregivers which includes social, psychological, physical or economic aspects. Research indicates that the disease is associated with plaques and tangles in the brain. Currently used treatments offer a small symptomatic benefit. No treatments to delay or halt the progression of the disease are, as of yet, available. The investigators suppose sodium oligo-mannurarate capsule to be effective to halt the progression of the disease.

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Sodium oligo-mannurarate 600mg intervention 2: Sodium oligo-mannurarate 900mg intervention 3: Placebo
Intervention descriptions: intervention 1: sodium oligo-mannurarate capsule 600mg twice a day for 24 weeks intervention 2: sodium oligo-mannurarate capsule 900mg twice a day for 24 weeks intervention 3: simulant of sodium oligo-mannurarate capsule

Protocol document: