Conditions: Pulmonary Arterial Hypertension
Keywords: Pulmonary Arterial Hypertension, tyrosine kinase inhibitor, STI571
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 59
Healthy volunteers: no

Brief summary:
This study will evaluate the safety, tolerability, and efficacy of imatinib mesylate in patients with pulmonary arterial hypertension

Detailed description:

Arms:
arm 1: STI571 arm 2: Placebo arm 3: Open label extension

Interventions: intervention 1: Imatinib mesylate intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: