Conditions: Cushing's Disease Cushing's Syndrome
Keywords: Cushing's Disease Cushing's Syndrome Cushings Pituitary Ectopic ACTH secretion
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 4
Healthy volunteers: no

Brief summary:
This is a compassionate use study. In addition to providing compassionate use access to mifepristone, objectives of the study will be to evaluate the safety and utility of mifepristone in the treatment of the signs and symptoms of endogenous Cushing's syndrome when given on a compassionate use basis. The study will only enroll subjects whose physicians have determined that medical treatment is needed to control the symptoms or signs of hypercortisolemia.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Mifepristone
Intervention descriptions: intervention 1: mifepristone at doses from 300mg/day up to 1200mg/day

Protocol document: