Conditions: Intraocular Pressure
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 413
Healthy volunteers: no

Brief summary:
The objective of this clinical investigation is to determine the most effective drug concentration(s) of BOL-303259-X in the reduction of IOP in order to support further clinical development of an appropriate dose with regard to efficacy, and ocular and systemic safety.

Detailed description:

Arms:
arm 1: ophthalmic solution arm 2: ophthalmic solution

Interventions: intervention 1: BOL-303259-X intervention 2: Latanoprost
Intervention descriptions: intervention 1: ophthalmic solution, various concentrations, once daily (QD) 28 days intervention 2: 0.005% ophthalmic solution, QD 28 days

Protocol document: