Conditions: Dental Plaque Gingivitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 120
Healthy volunteers: yes

Brief summary:
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental plaque and gingivitis.

Detailed description:

Arms:
arm 1: triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash arm 2: stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash arm 3: fluoride toothpaste + fluoride Mouthwash

Interventions: intervention 1: triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash intervention 2: stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash intervention 3: fluoride toothpaste + fluoride Mouthwash
Intervention descriptions: intervention 1: Brush whole mouth with Total toothpaste for 1 minute, 2 times/day for 6 weeks (study duration) using a Total 360 toothbrush. Immediately after each toothbrushing, rinse whole mouth with 20 ml of mouthwash for 30 seconds. intervention 2: Brush whole mouth with Crest Pro-Health toothpaste for 1 minute, 2 times/day for 6 weeks (study duration) using an Oral B Pro-Health toothbrush. Immediately after each toothbrushing, rinse whole mouth with 20 ml of Crest Pro-Health Multi-Protection mouthwash for 30 seconds. intervention 3: Brush whole mouth with Crest Cavity Protection toothpaste for 1 minute, 2 times/day for 6 weeks (study duration) using an Oral B Indicator toothbrush. Immediately after each toothbrushing, rinse whole mouth with 20 ml of Crest Pro-Health For Me Breezy Mint mouthwash for 30 seconds.

Protocol document: