Conditions: Oral Mucositis
Keywords: Mucositis Head and Neck Cancer Head and Neck Neoplasms Stomatitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 43
Healthy volunteers: no

Brief summary:
Oral mucositis refers to ulcerative lesions of the oral mucosa that occur due to radiation therapy given for treatment of head and neck cancer. These lesions are painful, compromise nutrition and quality of life and may necessitate interruptions in radiation therapy, thus adversely affecting cancer therapy outcomes. This study examined the use of an anti-inflammatory medicine to reduce pain and severity of oral mucositis.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: celecoxib intervention 2: placebo
Intervention descriptions: intervention 1: Subject was asked to take celecoxib each day that radiation therapy was given. intervention 2: Subject was asked to take placebo each day that radiation therapy was given.

Protocol document: