Conditions: Marijuana Smoking
Keywords: marijuana dronabinol pharmacotherapy
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 25
Healthy volunteers: yes

Brief summary:
Study participants received dronabinol (0, 120mg/day and 240mg/day) for 12 consecutive days in a randomized order. During each dronabinol maintenance period they were able to self-administer active or placebo cannabis using either a progressive ratio schedule or choice between cannabis and monetary alternative.

Detailed description:

Arms:
arm 1: Participants were administered dronabinol (0 mg/day, 120mg/day and 240mg/day) for 12 days each in a random order

Interventions: intervention 1: Dronabinol 120mg/day intervention 2: Placebo intervention 3: Dronabinol 240mg/day
Intervention descriptions: intervention 1: Participants receive 40mg dronabinol 3 times daily intervention 2: Participants receive placebo intervention 3: Participants receive 80mg dronabinol 3 times daily

Protocol document: