Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 58
Healthy volunteers: yes

Brief summary:
The data from this study will be used to compare the kinetic profile of metformin 500mg in linagliptin/metformin fixed dose combination tablet versus Canadian metformin reference product administered concomitantly with linagliptin 2.5 mg tablet.

Detailed description:

Arms:
arm 1: patient to receive a single medium dose combination tablet containing Linagliptin and Metformin once daily arm 2: patient to receive two individual tablets: Linagliptin and Metformin (medium dose)

Interventions: intervention 1: Metformin Single Tablet intervention 2: Linagliptin/Metformin Combo intervention 3: Linagliptin Single Tablet
Intervention descriptions: intervention 1: Metformin medium doseTablet intervention 2: Fixed dose combination intervention 3: Linagliptin Single medium dose Tablet

Protocol document: