Conditions: Labor Pain
Keywords: non narcotic epidural labor pain Non narcotic treatment of labor pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 200
Healthy volunteers: no

Brief summary:
The purpose of this study is to see which dose of epidural neostigmine is the best additive to use with the numbing medication used in an epidural during labor.

Detailed description:
This study is examining the use of the non-narcotic medication, neostigmine, in combination with the local anesthetic bupivacaine when compared with the commonly used narcotic fentanyl in providing pain relief with the fewest side effects in labor analgesia.

Arms:
arm 1: STUDY DRUG INFUSION WITH NEOSTIGMINE 8 MCG/ML arm 2: STUDY DRUG INFUSION CONC NEOSTIGMINE 4 MCG/ML arm 3: STUDY DRUG INFUSION NEOSTIGMINE 2 MCG/ML arm 4: Bupivacaine with fentanyl 2 mcg/ml. STANDARD INFUSION

Interventions: intervention 1: Neostigmine intervention 2: Bupivacaine intervention 3: fentanyl
Intervention descriptions: intervention 1: utilizing 3 different dosages of neostigmine and comparing it to the standard of fentanyl. Infusion runs via PCA throughout labor analgesia. intervention 2: None intervention 3: fentanyl 2 mcg/ml

Protocol document: