Conditions: Rheumatoid Arthritis
Keywords: Rheumatoid Arthritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 112
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the Efficacy, Safety, and Pharmacokinetics of MP-435 administered for 12 weeks in subjects with rheumatoid arthritis (RA) on stable doses of Methotrexate.

Detailed description:

Arms:
arm 1: dose1 arm 2: Placebo

Interventions: intervention 1: MP-435(dose1) + Methotrexate intervention 2: Placebo + Methotrexate
Intervention descriptions: intervention 1: MP-435 dose1 + stable weekly dose of Methotrexate intervention 2: Placebo + stable weekly dose of Methotrexate

Protocol document: