Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 32
Healthy volunteers: yes

Brief summary:
To establish bioequivalence (BE) under fed conditions between metformin in linagliptin/metformin fixed dose combination tablet and metformin reference product administered in free combination togther with linagliptin

Detailed description:

Arms:
arm 1: fixed dose combination tablet (FDC) arm 2: single tablets

Interventions: intervention 1: Linagliptin/metformin intervention 2: Metformin intervention 3: Linagliptin
Intervention descriptions: intervention 1: FDC intervention 2: single tablet Metformin intervention 3: single tablet Linagliptin

Protocol document: