Conditions: Diabetes Type 2
Keywords: Diabetes, Type 2, exenatide, Sitagliptin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 365
Healthy volunteers: no

Brief summary:
To compare the effect on glycemic control (HbA1c) of exenatide suspension administered once weekly to that achieved by sitagliptin or placebo administered once daily for 28 weeks in subjects with type 2 diabetes mellitus.

Detailed description:

Arms:
arm 1: Exenatide once weekly suspension 2mg subcutaneous injection arm 2: Overencapsulated Sitagliptin 100mg oral tablet once daily arm 3: Placebo oral capsule once daily

Interventions: intervention 1: Exenatide once weekly suspension intervention 2: Sitagliptin intervention 3: Placebo
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: Placebo oral capsule once daily

Protocol document: