Conditions: Anemia, Kidney Disease, Chronic
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 87
Healthy volunteers: no

Brief summary:
This comparative, open-label, multicenter, parallel-group study evaluated the effect of altitude on the dose requirements of Mircera (methoxy polyethylene glycol-epoetin beta) to achieve a target hemoglobin concentration of 11-12 grams per deciliter (g/dL) in participants with chronic renal anemia in pre-dialysis and dialysis. Four groups of participants, at sea level (below 50 meters) or an altitude above 1800 meters, and pre-dialysis or dialysis, received 50-250 micrograms (mcg) Mircera subcutaneously (SC), according to the local prescribing label.

Detailed description:

Arms:
arm 1: Participants received 50-250 mcg SC according to local label. arm 2: Participants received 50-250 mcg SC according to local label. arm 3: Participants received 50-250 mcg SC according to local label. arm 4: Participants received 50-250 mcg SC according to local label.

Interventions: intervention 1: Methoxy polyethylene glycol-epoetin beta
Intervention descriptions: intervention 1: Participants received 50-250 mcg SC according to local label

Protocol document: