Conditions: HIV
Keywords: HIV Prevention Non-occupational Post-Exposure Prophylaxis (NPEP) Post-Exposure Prophylaxis (PEP)
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 11
Healthy volunteers: yes

Brief summary:
This study will evaluate how safe and tolerable a combination of taking three-drugs will be for the purpose of preventing HIV transmission after a high-risk sexual contact exposure in HIV uninfected adults.

Detailed description:
Participants are given a regimen containing tenofovir disoproxil fumarate (TDF) 300mg and emtricitabine (FTC) 200mg fixed-dose combination tablet (TDF/FTC) once daily, and atazanavir, one 300mg tablet and one 100 mg ritonavir given once daily,for 28 days.

Arms:
arm 1: Tenofovir DF and Emtricitabine; Ritonavir-boosted Atazanavir

Interventions: intervention 1: Tenofovir DF and Emtricitabine; Ritonavir-boosted Atazanavir
Intervention descriptions: intervention 1: TDF 300mg and FTC 200mg fixed-dose combination tablet (TDF/FTC) once daily, and atazanavir, one 300mg tablet and one 100 mg ritonavir given once daily

Protocol document: