Conditions: Opioid-Induced Constipation (OIC)
Keywords: Non-Cancer-Related Pain Opioid-Induced Constipation.
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 302
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effect and safety of NKTR-118 treatment of opioid-induced constipation in patients with non-cancer-related pain over a 6-month period.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: NKTR-118 intervention 2: NKTR-118 intervention 3: Placebo
Intervention descriptions: intervention 1: 12.5 mg oral tablet once daily intervention 2: 25 mg oral tablet once daily intervention 3: Oral tablet intake once daily

Protocol document: