Conditions: Healthy Volunteers
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 30
Healthy volunteers: yes

Brief summary:
Compare the pharmacokinetic profiles when the contents are emptied into a soft food and orange juice compared to the SPD489 when swallowed as an intact capsule.

Detailed description:

Arms:
arm 1: lisdexamfetamine dimesylate 70 mg capsule administered under fasted conditions arm 2: Lisdexamfetamine Dimesylate 70mg capsule mixed into vanilla yogurt arm 3: Lisdexamfetamine Dimesylate 70mg capsule mixed into orange juice

Interventions: intervention 1: Lisdexamfetamine Dimesylate
Intervention descriptions: intervention 1: Single dose of a 70 mg capsule on Day 1

Protocol document: