Conditions: Deep Extubation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 62
Healthy volunteers: no

Brief summary:
It has been reported that deep extubation can reduce cardiopulmonary complication against endotracheal tube extubation during emergence from general anesthesia. The investigators hypothesized that using desflurane with target controlled infusion of remifentanil is more effective than using desflurane alone during deep extubation. The purpose of this study is to evaluate the effect of remifentanil to prevent respiratory complication (etc. coughing) during emergence from general anesthesia.

Detailed description:

Arms:
arm 1: 1.5 MAC desflurane until extubation arm 2: 1.0 MAC desflurane with 1.0ng/ml targeted concentration infusion of remifentanil

Interventions: intervention 1: Desflurane with remifentanil intervention 2: Desflurane
Intervention descriptions: intervention 1: During the emergence from anesthesia,extubation was performed under 1.0 MAC desflurane with 1.0ng/ml remifentanil intervention 2: During the emergence from anesthesia,extubation was performed under 1.5 MAC desflurane

Protocol document: