Conditions: Pelvic Pain Associated With Refractory Endometriosis
Keywords: Menstrual pain Refractory endometriosis Pelvic pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 27
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory endometriosis

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: BGS649 intervention 2: Placebo
Intervention descriptions: intervention 1: 0.1 mg capsules for oral administration. A total dose of 3 capsules of BGS649 0.1mg will be administered at randomization, week 4, and week 8 at the study site. intervention 2: Placebo matching BGS649 will be provided by Novartis as capsules for oral administration. Three capsules of placebo will be administered at randomization, week 4, and week 8 at the study site.

Protocol document: