Conditions: Dental Plaque Gingivitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 129
Healthy volunteers: yes

Brief summary:
The objective of this clinical research study is to evaluate clinical efficacy of Colgate Total Toothpaste as compared to Crest Pro-Health Toothpaste and Crest Pro-Health Mouthwash, and Crest Cavity Protection Toothpaste and Crest Fluoride Mouthwash in reducing gingivitis and dental plaque in adults in a six-week clinical study.

Detailed description:

Arms:
arm 1: Triclosan/fluoride toothpaste arm 2: Stannous fluoride toothpaste \& cetylpyridinium chloride Mouthwash arm 3: fluoride toothpaste +fluoride mouthwash

Interventions: intervention 1: Triclosan/fluoride toothpaste intervention 2: stannous fluoride toothpaste intervention 3: fluoride toothpaste intervention 4: Fluoride Mouthwash intervention 5: cetylpyridinium chloride Mouthwash
Intervention descriptions: intervention 1: Brush whole mouth with Total toothpaste (sold in the US), using a Total 360 toothbrush, 2 times/day for 6 weeks (study duration). intervention 2: Brush whole mouth with Crest Pro-Health toothpaste using an Oral B Pro-Health toothbrush for 1 minute, 2 times/day for 6 weeks (study duration). intervention 3: Brush whole mouth with Crest Cavity Protection toothpaste using an Oral B Indicator toothbrush for 1 minute, 2 times/day for 6 weeks (study duration). intervention 4: Immediately after each toothbrushing rinse whole mouth with 20 ml of Crest fluoride Mouthrinse for 30 seconds each time. intervention 5: Immediately after each toothbrushing rinse whole mouth with 20 ml of Crest Pro-Health Mouthrinse for 30 seconds each time.

Protocol document: