Conditions: Chronic Stable Angina
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 186
Healthy volunteers: no

Brief summary:
The objective of this study is to evaluate the dose-response of three different dose levels of STA-2 (900 mg daily, 1800 mg daily and 2700 mg daily for 42 days) versus placebo in patients with chronic stable angina.

Detailed description:
The objective of this study is to evaluate the dose-response of three different dose levels of STA-2 (900 mg daily, 1800 mg daily and 2700 mg daily for 42 days) versus placebo in patients with chronic stable angina.

Treatment Group A:

150 mg STA-2, 2 capsules t.i.d., after meal (900 mg STA-2 total dose per day)

Treatment Group B:

300 mg STA-2, 2 capsules t.i.d., after meal (1800 mg STA-2 total dose per day)

Treatment Group C:

450 mg STA-2, 2 capsules t.i.d., after meal (2700 mg STA-2 total dose per day)

Placebo Group:

Placebo capsule, 2 capsules t.i.d., after meal

Arms:
arm 1: placebo capsule 2# t.i.d./day arm 2: 150 mg STA-2, 2 capsules t.i.d., after meal (900 mg STA-2 total dose per day) arm 3: 300 mg STA-2, 2 capsules t.i.d., after meal (1800 mg STA-2 total dose per day) arm 4: 450 mg STA-2, 2 capsules t.i.d., after meal (2700 mg STA-2 total dose per day)

Interventions: intervention 1: green tea polyphenols (STA-2)
Intervention descriptions: intervention 1: 2 capsules t.i.d., after meal

Protocol document: