Conditions: Conscious Sedation
Keywords: Sedation Gabapentin ERCP Endoscopy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 56
Healthy volunteers: no

Brief summary:
The standard approach to sedation in endoscopic retrograde cholangiopancreatography (ERCP) involves the use of benzodiazepines and opiates to achieve a moderate depth of sedation. There is data to suggest supplementing this regimen with gabapentin may lead to reduced pain, higher patient satisfaction and lower opiate requirements. The investigators are conducting a clinical trial to study this hypothesis.

Detailed description:

Arms:
arm 1: Patients will receive combination opiate and benzodiazepine for sedation, the current standard of care. arm 2: Patients will receive gabapentin 900mg PO x 1 dose, one hour prior to the procedure. At the time of ERCP, patients will be sedated in a standard fashion.

Interventions: intervention 1: Gabapentin intervention 2: Standard sedation regimen
Intervention descriptions: intervention 1: gabapentin 900mg PO x 1 dose, 1 hour prior to the procedure intervention 2: Combination opiate and benzodiazepine will be administered to achieve moderate sedation. This is the standard of care.

Protocol document: