Conditions: Psoriasis Vulgaris
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of the study is to evaluate the anti-psoriatic effect of LEO 35299 in different formulations, compared to Daivonex® ointment and Daivonex® ointment vehicle, using the psoriasis plaque test modified from the method developed by KJ Dumas and JR Scholtz.

Detailed description:

Arms:

Interventions: intervention 1: B LEO 35299 20 mg/g cream intervention 2: C LEO 35299 20 mg/g cream intervention 3: E LEO 35299 10 mg/g solution intervention 4: F LEO 35299 10 mg/g solution intervention 5: Daivonex® ointment intervention 6: Daivonex® ointment vehicle
Intervention descriptions: intervention 1: once daily application, 3 weeks intervention 2: once daily application, 3 weeks intervention 3: once daily application, 3 weeks intervention 4: once daily application, 3 weeks intervention 5: once daily application, 3 weeks intervention 6: once daily application, 3 weeks

Protocol document: