Conditions: Acne Vulgaris
Keywords: acne anti-androgen clascoterone cassiopea
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 363
Healthy volunteers: no

Brief summary:
CB-03-01 is being developed for the topical treatment of acne vulgaris, an androgen-dependent skin disorder. The purpose of this study is to compare the safety and efficacy of multiple concentrations of CB-03-01 to vehicle in the treatment of acne vulgaris.

Detailed description:

Arms:
arm 1: low dose of CB-03-01, 0.1% applied twice a day arm 2: medium dose of CB-03-01, 0.5% applied twice a day arm 3: high dose of CB-03-01, 1% applied once a day arm 4: high dose of CB-03-01, 1% applied twice a day arm 5: vehicle cream, applied once or twice a day

Interventions: intervention 1: CB-03-01 intervention 2: Vehicle intervention 3: CB-03-01
Intervention descriptions: intervention 1: Topical cream, applied once a day intervention 2: Topical cream, applied once or twice a day intervention 3: Topical cream, applied twice a day

Protocol document: