Conditions: Healthy Volunteers
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 8
Healthy volunteers: yes

Brief summary:
The purpose of this study is to compare how much baricitinib (study drug) gets into the blood stream when it is given as a single dose (in tablet form) and as an intravenous infusion (injection given directly into a vein via a small needle). Each participant in the study will make four visits to the investigator site over the course of about 6 weeks.

Detailed description:

Arms:
arm 1: Single oral dose of baricitinib and single intravenous (IV) infusion of \[\^13C4D3\^15N\]-baricitinib over 1.5 hours.

Interventions: intervention 1: Baricitinib intervention 2: [^13C4D3^15N]-baricitinib
Intervention descriptions: intervention 1: 4 milligrams (mg) administered orally intervention 2: 4 micrograms (μg) administered intravenously (IV)

Protocol document: