Conditions: Epilepsy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 56
Healthy volunteers: yes

Brief summary:
Single-centre, open-label, randomized, two-sequence, two-way crossover study. The study consisted of two consecutive single-dose treatment periods separated by a washout period of 10 to 14 days or more.

Detailed description:
Single-centre, open-label, randomized, two-sequence, two-way crossover study. The study consisted of two consecutive single-dose treatment periods separated by a washout period of 10 to 14 days or more. In Group 1 the volunteers received a single oral dose of 25 mg OPC. In Group 2 the volunteers received a single oral dose of 50 mg OPC

Arms:
arm 1: Period 1 - 5x5 mg OPC Period 2 - 1x25 mg OPC arm 2: Period 1 - 1x25 mg OPC Period 2 - 5x5 mg OPC arm 3: Period 1 - 2x25 mg OPC Period 2 - 1x50 mg OPC arm 4: Period 1 - 1x50 mg OPC Period 2 - 2x25 mg OPC

Interventions: intervention 1: BIA 9-1067
Intervention descriptions: intervention 1: None

Protocol document: