Conditions: Chronic Hepatitis C Hemophilia
Keywords: Hepatitis C HCV Hemophilia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 5
Healthy volunteers: no

Brief summary:
This study will examine viral dynamic responses in subjects with chronic hepatitis C and hemophilia when treated with pegylated interferon + ribavirin and telaprevir.

Detailed description:
Previous clinical trials for treatment of chronic hepatitis C have excluded subjects with hemophilia from participating.

Arms:
arm 1: Kinetic assessment of response guided treatment per standard of care with PegInterferon + Ribavirin for 4 weeks followed by 12 weeks of PegInterferon + Ribavirin + Telaprevir followed by variable duration of PegInterferon + Ribavirin arm 2: Kinetic assessment of response guided treatment per standard of care with PegInterferon + Ribavirin + Telaprevir for 12 weeks followed by variable duration of PegIntereron + Ribavirin

Interventions: intervention 1: PegInterferon intervention 2: Ribavirin intervention 3: Telaprevir
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None

Protocol document: