Conditions: Chronic Obstructive Pulmonary Disease COPD
Keywords: Chronic Obstructive Pulmonary Disease COPD
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 64
Healthy volunteers: no

Brief summary:
This study evaluated the safety and efficacy of once and twice daily TD-4208 and placebo when administered using a jet nebulizer for 7 days in a cross-over design to patients with moderate to severe chronic obstructive pulmonary disease.

Detailed description:

Arms:
arm 1: TD-4208 inhalation solution 44 mcg twice daily for 7 days arm 2: Placebo inhalation solution twice daily for 7 days arm 3: TD-4208 inhalation solution 175 mcg once daily, placebo once daily

Interventions: intervention 1: TD-4208 intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: