Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 83
Healthy volunteers: yes

Brief summary:
The primary objective of this trial was to investigate safety and tolerability of multiple doses of BI 409306 in healthy young and elderly volunteers.

The secondary objective was to explore the pharmacokinetics and pharmacodynamics of multiple doses of BI 409306 in healthy young and elderly volunteers

Detailed description:

Arms:
arm 1: Placebo - Young Subjects arm 2: Placebo - Elderly Subjects arm 3: 25 milligram (mg) of BI 409306 were administered in young subjects once daily (QD). arm 4: 25 mg of BI 409306 were administered in elderly subjects once daily (QD). arm 5: 50 mg of BI 409306 were administered in young subjects once daily (QD). arm 6: 50 mg of BI 409306 were administered in young subjects twice daily (BID). arm 7: 50 mg of BI 409306 were administered in elderly subjects once daily arm 8: 100 mg of BI 409306 were administered in young subjects once daily (QD). arm 9: 100 mg of BI 409306 were administered in elderly subjects once daily (QD).

Interventions: intervention 1: BI 409306 intervention 2: Placebo
Intervention descriptions: intervention 1: Film-coated tablet intervention 2: Film-coated tablet

Protocol document: