Conditions: Chronic Otitis Media
Keywords: myringotomy pressure equalization tubes
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 100
Healthy volunteers: no

Brief summary:
This is a study to compare intranasal dexmedetomidine to intranasal fentanyl following anesthesia induction in patients undergoing myringotomy and placement of pressure equalization (PE) tubes in providing analgesia and smoothing emergence from general anesthesia.

Detailed description:

Arms:
arm 1: Midazolam 0.5 mg/kg given orally pre-op and 1 dose of dexmedetomidine 1mcg/kg given intranasally in OR. arm 2: Midazolam 0.5 mg/kg given orally pre-op and 1 dose of fentanyl 2mcg/kg given intranasally in OR. arm 3: 1 dose of dexmedetomidine 1mcg/kg given intranasally in OR without any pre-medication. arm 4: 1 dose of fentanyl 2mcg/kg given intranasally in the OR without any pre-medication.

Interventions: intervention 1: Dexmedetomidine intervention 2: Fentanyl intervention 3: Midazolam
Intervention descriptions: intervention 1: dexmedetomidine (1 µg/kg) will be administered intranasally intervention 2: fentanyl (2 µg/kg) will be administered intranasally intervention 3: Sedative given pre-op.

Protocol document: