Conditions: Safety Tolerability Pharmacokinetics Cancer
Keywords: Dexanabinol Oral Safety Tolerability Pharmacokinetics
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 40
Healthy volunteers: yes

Brief summary:
The purpose of this study is to test the safety and observe the pharmacokinetics (distribution and elimination of the drug) of the compound dexanabinol (ETS2101) in healthy male subjects following a single oral dose.

Detailed description:

Arms:
arm 1: Single oral dose of dexanabinol arm 2: Single oral dose of dexanabinol arm 3: Single oral dose of dexanabinol arm 4: Single oral dose of dexanabinol arm 5: Single oral dose of dexanabinol arm 6: Single oral dose of matching placebo

Interventions: intervention 1: Dexanabinol Dose Level 1 intervention 2: Dexanabinol Dose Level 2 intervention 3: Dexanabinol Dose Level 3 intervention 4: Dexanabinol Dose Level 4 intervention 5: Dexanabinol Dose Level 5 intervention 6: Placebo
Intervention descriptions: intervention 1: Oral formulation of dexanabinol intervention 2: Oral formulation of dexanabinol intervention 3: Oral formulation of dexanabinol intervention 4: Oral formulation of dexanabinol intervention 5: Oral formulation of dexanabinol intervention 6: None

Protocol document: