Conditions: Renal Impairment Renal Insufficiency Kidney Disease Kidney Diseases
Keywords: pharmacokinetics pharmacodynamics renal impairment
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 16
Healthy volunteers: yes

Brief summary:
This is an open-label, parallel-group study to compare the pharmacokinetics and pharmacodynamics of IDN-6556 following a single 50 mg oral dose of IDN-6556 in subjects with severe renal impairment and matched healthy volunteers with normal renal function.

Detailed description:

Arms:
arm 1: All subjects receive a single 50 mg oral dose of IDN-6556 arm 2: All subjects receive a single 50 mg oral dose of IDN-6556

Interventions: intervention 1: IDN-6556
Intervention descriptions: intervention 1: None

Protocol document: