Conditions: Erectile Dysfunction
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 383
Healthy volunteers: no

Brief summary:
The primary objective of this study is to evaluate whether, after two 8-week treatment periods, male patients with erectile dysfunction (ED) in China prefer 20 milligram (mg) tadalafil or 100 mg sildenafil. This trial consists of two treatment periods of 8 weeks each and an extension phase of 8 weeks, for a total of 24 weeks.

Detailed description:

Arms:
arm 1: 20 mg tadalafil taken orally, as needed, for 8 weeks, followed by 100 mg sildenafil taken orally, as needed, for an additional 8 weeks. There is a washout period of 7-10 days between treatments.

At the end of the two 8-week treatment periods, participants will be allowed to enter an 8-week extension phase on their preferred medication for erectile dysfunction (ED). arm 2: 100 mg sildenafil taken orally, as needed, for 8 weeks, followed by 20 mg tadalafil taken orally, as needed, for an additional 8 weeks. There is a washout period of 7-10 days between treatments.

At the end of the two 8-week treatment periods, participants will be allowed to enter an 8-week extension phase on their preferred medication for ED.

Interventions: intervention 1: Tadalafil intervention 2: Sildenafil
Intervention descriptions: intervention 1: Administered Orally intervention 2: Administered Orally

Protocol document: