Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 36
Healthy volunteers: yes

Brief summary:
The objective of the current study is to demonstrate bioequivalence of two 2.5 mg linagliptin/500 mg metformin fixed dose combination tablets compared to the free combination of the linagliptin 5 mg and metformin 1000 mg in healthy male and female volunteers.

Detailed description:

Arms:
arm 1: Linagliptin/Metformin arm 2: Linagliptin and Metformin

Interventions: intervention 1: Metformin intervention 2: Linagliptin intervention 3: Metformin intervention 4: Linagliptin
Intervention descriptions: intervention 1: Free combination intervention 2: Fixed dose combination intervention 3: Combination intervention 4: Free combination

Protocol document: