Conditions: Renal Impairment
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 32
Healthy volunteers: no

Brief summary:
The primary objective was to evaluate the incidence of clinically significant hypocalcemia following multiple 120 mg subcutaneous doses of denosumab in patients with severe chronic kidney disease (CKD) and CKD on dialysis

Detailed description:

Arms:
arm 1: Participants received two 120 mg doses of denosumab administered subcutaneously on Day 1 and Day 29.

Interventions: intervention 1: Denosumab
Intervention descriptions: intervention 1: Adminstered by subcutaneous injection

Protocol document: