Conditions: Type 2 Diabetes Mellitus
Keywords: insulin resistance
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 146
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy and safety of Canagliflozin (TA-7284) in combination with Insulin in patients with type 2 Diabetes for 16 weeks administration.

Detailed description:
This is a randomized, 2-arm, parallel group, double blind study to evaluate the efficacy and safety of Canagliflozin (TA-7284) in Japanese patients with type 2 diabetes mellitus, who are receiving treatment with insulin therapy on diet and exercise and have inadequate glycemic control. The patients will receive either TA-7284 100mg or Placebo orally for 16 weeks.

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Canagliflozin (TA-7284) intervention 2: Placebo intervention 3: Insulin
Intervention descriptions: intervention 1: The patients will receive Canagliflozin orally for 16 weeks intervention 2: The patients will receive Placebo orally for 16 weeks intervention 3: None

Protocol document: