Conditions: Geographic Atrophy Age-Related Macular Degeneration
Keywords: Geographic Atrophy GA Age-Related Macular Degeneration AMD
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 772
Healthy volunteers: no

Brief summary:
The purpose of this study was to evaluate the safety and efficacy of AL-8309B Ophthalmic Solution versus Vehicle administered as a topical ocular drop for the treatment for geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Detailed description:

Arms:
arm 1: AL-8309B 1.0% Ophthalmic Solution, 1 drop in each eye twice daily for 30 months, up to a maximum of 36 months arm 2: AL-8309B 1.75% Ophthalmic Solution, 1 drop in each eye twice daily, for 30 months up to a maximum of 36 months arm 3: AL-8309B Vehicle, 1 drop in each eye twice daily, for 30 months up to a maximum of 36 months

Interventions: intervention 1: AL-8309B Ophthalmic Solution intervention 2: AL-8309B Vehicle
Intervention descriptions: intervention 1: None intervention 2: Inactive ingredients used as placebo comparator

Protocol document: