Conditions: Healthy Volunteer
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 16
Healthy volunteers: yes

Brief summary:
This open-label, prospective, single dose study will evaluate the pharmacokinetics and safety of Tamiflu (oseltamivir) in volunteers on dialysis and in volunteers with a creatinine clearance from 10 to 30 mL/min. Volunteers will receive a single oral dose of Tamiflu.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Tamiflu (oseltamivir) intervention 2: Tamiflu (oseltamivir)
Intervention descriptions: intervention 1: Single dose of Tamiflu in volunteers on dialysis intervention 2: Single dose of Tamiflu in volunteers with creatinine clearance from 10 to 30 mL/min

Protocol document: