Conditions: Trichotillomania
Keywords: hair pulling
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 51
Healthy volunteers: no

Brief summary:
This is an 8-week, double-blind study of Natrexone in the treatment of trichotillomania

Detailed description:
The goal of the proposed study is to evaluate the efficacy of Naltrexone in trichotillomania. Forty subjects with DSM-IV trichotillomania will receive 8 weeks of double-blind Naltrexone or placebo. The hypothesis to be tested is that Naltrexone will be effective and well tolerated in patients with trichotillomania compared to placebo. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Arms:
arm 1: Naltrexone arm 2: Placebo

Interventions: intervention 1: Naltrexone intervention 2: Placebo
Intervention descriptions: intervention 1: pill, by mouth, 50mg-150mg/day for the duration of the study intervention 2: pill, by mouth, daily

Protocol document: