Conditions: Atrial Fibrillation
Keywords: atrial fibrillation fish oil
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1516
Healthy volunteers: no

Brief summary:
This is a large multi-center study to examine whether peri-operative intake of n-3 polyunsaturated fatty acids (PUFA) will reduce the occurrence of post-operative atrial fibrillation or flutter (AF) in patients undergoing cardiac surgery (CS).

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Omega -3 fatty acids intervention 2: Placebo
Intervention descriptions: intervention 1: 10g dose of oral omega-3 fatty acid capsules over 3-5 days before surgery (or 8 g over 2 days before surgery), including the morning of surgery, followed by 2g/d after surgery for 10 days, or until discharge, whichever occurs first. intervention 2: Olive Oil capsules

Protocol document: