Conditions: Pain
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 15
Healthy volunteers: no

Brief summary:
The rationale of this study is to map out changes in temperature distribution brought about by topical application of our test product, and use this physiological phenomenon to visualize the onset of action involved in overall mechanism of action of the product.

Detailed description:

Arms:
arm 1: 2 ± 0.2 g of product will be gently rubbed for 15 seconds on the affected knee joint. arm 2: 2 ± 0.2 g of product will be gently rubbed for 15 seconds on the affected knee joint.

Interventions: intervention 1: IODEX® balm intervention 2: Placebo balm
Intervention descriptions: intervention 1: 2 ± 0.2 g of test balm will be applied topically in a crossover fashion at a gap of 3 days between the two product applications. intervention 2: 2 ± 0.2 g of placebo balm will be applied topically in a crossover fashion at a gap of 3 days between the two product applications.

Protocol document: