Conditions: Congenital Heart Disease
Keywords: Single ventricle congenital heart disease
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 10
Healthy volunteers: no

Brief summary:
Recent studies have shown beneficial effects of sildenafil in patients with single ventricle congenital heart disease. The purpose of this study is to determine whether Bosentan, a drug with similar effects, will have similar benefit in this patient population.

Detailed description:
Patients enrolled in the study will take Bosentan. Baseline and follow up measurements will be collected then analyzed.

Arms:
arm 1: Bosentan

Interventions: intervention 1: Bosentan
Intervention descriptions: intervention 1: Bosentan 62.5 mg tablet taken orally twice daily for one month, followed by Bosentan 125 mg tablet taken orally twice daily for three months.

Protocol document: