Conditions: Prostate Cancer
Keywords: prostate cancer prostatectomy neoadjuvant
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 52
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine if enzalutamide is an effective therapy in treating localized prostate cancer prior to prostatectomy.

Detailed description:

Arms:
arm 1: Enzalutamide 160 mg, orally, once daily arm 2: Enzalutamide 160 mg, orally, once daily and leuprolide 22.5 mg, intramuscular injection, every 3 months, and dutasteride, 0.5 mg, orally, once daily

Interventions: intervention 1: Enzalutamide intervention 2: Leuprolide intervention 3: Dutasteride
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None

Protocol document: