Conditions: Glioblastoma Multiforme Brain Metastases
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate diagnostic imaging techniques using 124I-NM404 PET/CT in human brain tumors. This goal will be accomplished by quantifying tumor uptake and determining the optimal PET/CT protocol, comparing PET tumor uptake to MRI, and calculating tumor dosimetry. The long-term goals of this research are to improve the diagnosis and treatment of malignant brain tumors by using radioiodinated NM404

Detailed description:

Arms:
arm 1: injection of I-124NM404 for imaging

Interventions: intervention 1: NM404 intervention 2: NM404
Intervention descriptions: intervention 1: injection of 5.0mCi I-124 NM404 Arms: I124-NM404 brain metastases or GBM imaging

Other Names:

PET imaging with I-124 NM404 intervention 2: injection of an experimental imaging agent, 5mCi I-124NM404

Protocol document: