Conditions: Asthma
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 14
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether a single IV dose of N6022 will have a significant bronchoprotective effect, compared with placebo, during methacholine challenge.

Detailed description:
The number of patients with adverse events measured in both the treated and placebo groups from start of dosing until Day 28 post dose.

Arms:
arm 1: N6022 - 5 mg arm 2: Placebo

Interventions: intervention 1: Active intervention 2: Placebo
Intervention descriptions: intervention 1: A 5 mg single dose given intravenously via syringe pump over 1 minute. intervention 2: Same as active

Protocol document: