Conditions: Ocular Hypertension Open Angle Glaucoma
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 25
Healthy volunteers: no

Brief summary:
This clinical investigation is being performed to compare the effect of BOL-303259-X dosed once daily (QD) with timolol maleate 0.5% dosed twice daily (BID) in reducing intraocular pressure (IOP) measured over a 24-hour period in subjects with open-angle glaucoma (OAG) or ocular hypertension (OHT).

Detailed description:

Arms:
arm 1: Timolol maleate ophthalmic solution 0.5% administered 1 drop BID once in morning and once in the evening for 4 weeks. arm 2: BOL-303259-X topical ophthalmic solution administered 1 drop QD in the evening for 4 weeks.

Interventions: intervention 1: BOL-303259-X intervention 2: Timolol maleate
Intervention descriptions: intervention 1: Topical ophthalmic solution intervention 2: Topical ophthalmic solution

Protocol document: