Conditions: Healthy Volunteers
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 40
Healthy volunteers: yes

Brief summary:
The purpose of this study is to measure how much of the drug gets into the blood stream and how long it takes the body to get rid of it when given to healthy participants. Information about any side effects that may occur will also be collected.

The study has 2 periods. In each period, participants will take the study drug for 10 days, either with or without a meal. There is a minimum 14-day washout between each period.

This study is approximately 50 days, not including screening. Screening is required within 28 days prior to the start of the study.

Detailed description:

Arms:
arm 1: 130 milligram (mg) oral dose of evacetrapib once daily in a fasted state for 10 days. arm 2: 130 mg oral dose of evacetrapib once daily following a high-fat breakfast for 10 days.

Interventions: intervention 1: Evacetrapib intervention 2: High-fat Meal
Intervention descriptions: intervention 1: Administered orally intervention 2: Administered orally, at breakfast.

Protocol document: