Conditions: Hyperglycemia
Keywords: corticosteroid hyperglycemia hospital corticosteroid induced hyperglycemia in the hospital
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 72
Healthy volunteers: no

Brief summary:
The objective of this study is to determine the best insulin regimen for hospitalized patients who receive high doses of steroids who have high blood glucose.

Detailed description:
The overall study objective of this research is to establish the efficacy and assure the safety of achieving glycemic control in hospitalized patients who receive greater than physiologic doses of steroids. This study will compare 2 methods of achieving glycemic control in hospitalized patients who develop steroid-induced hyperglycemia (blood glucose (BG) \>180 mg/dL): 1) a study-specific steroid NPH dosing algorithm plus standard recommended care (Experimental group) vs. 2) the standard recommended care (Methodist Hospital Complete Insulin Orders (Control group).

Arms:
arm 1: a study-specific steroid (NPH) dosing algorithm plus standard recommended care. The intervention is Neutral Protamine Hagedorn (NPH) insulin plus complete insulin orders (CIO). arm 2: the standard recommended care (Methodist Hospital Complete Insulin Orders)

Interventions: intervention 1: NPH insulin plus Complete Insulin Orders intervention 2: Complete Insulin Orders
Intervention descriptions: intervention 1: NPH dosed per study-specific algorithm which incorporates total daily dosage of steroid to determine NPH dose. Complete insulin orders include background, meal-time and correction factor. intervention 2: 3-part insulin which includes background, meal-time and correction factor

Protocol document: