Conditions: Spinal Cord Diseases Spinal Cord Injuries Neuralgia Pain
Keywords: Central Nervous System Diseases Therapeutic Uses Wounds and Injuries Trauma Nervous System pregabalin
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 104
Healthy volunteers: no

Brief summary:
The purpose of this study is to assess the safety of the long-term use of pregabalin at doses up to 600 mg/day in patients with central neuropathic pain (post spinal cord injury pain, post stroke pain, and multiple sclerosis pain).

Detailed description:

Arms:
arm 1: Flexible dosing in 4 weeks followed by 48 weeks maintenance and one week taper period

Interventions: intervention 1: pregabalin
Intervention descriptions: intervention 1: Pregabalin capsules taken twice a daily (150-600mg/day)

Protocol document: