Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 30
Healthy volunteers: yes

Brief summary:
This is a randomized, open-label study to evaluate the effect of a single dose of SSP-004184 on the pharmacokinetics of a single dose of simvastatin in healthy adult subjects.

Detailed description:

Arms:
arm 1: Administered as a single oral 20 mg dose on Day 1. arm 2: Simvastatin (20 mg) + SSP-004184SS (30 mg/kg) administered concomitantly as a single oral dose on Day 1.

Interventions: intervention 1: Simvastatin intervention 2: SSP-004184SS
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: