Conditions: Rosacea
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 170
Healthy volunteers: no

Brief summary:
The objective of this study is to determine the clinical effects of doxycycline 40 mg (30 mg immediate release and 10 mg delayed release beads) capsules (Oracea®) as compared to placebo in the skin of adults with papulopustular rosacea and to identify a correlation, if any, with rosacea-related inflammatory markers.

Detailed description:

Arms:
arm 1: Doxycycline 40 mg (30 mg immediate release / 10 mg delayed release beads) Capsules arm 2: placebo

Interventions: intervention 1: Doxycycline intervention 2: Placebo
Intervention descriptions: intervention 1: doxycycline 40 mg (30 mg immediate release / 10 mg delayed release beads) Capsules, oral, one capsule daily in the morning intervention 2: Placebo, oral, one capsule daily in the morning

Protocol document: