Conditions: Sedation
Keywords: propofol alfentanil nitrous oxide moderate procedural sedation Moderate Procedural Sedation in the Emergency Department
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 126
Healthy volunteers: no

Brief summary:
This is a clinical trial of propofol and alfentanil as agents for moderated procedural sedation in patients undergoing sedation in the emergency department (ED).

Detailed description:
This was initially going to be a trial of propofol vs alfentanil vs nitrous oxide, but our use of nitrous oxide was discontinued before the trial began and the trial was conducted with only two arms

Arms:
arm 1: Propofol 1m g/kg IV followed by 0.5 mg/kg IV prn sedation arm 2: Sedation using alfentanil 10 ug/kg followed by 5 ug/kg prn sedation

Interventions: intervention 1: Propofol intervention 2: Alfentanil
Intervention descriptions: intervention 1: Propofol 1 mg/kg IV followed by 0.5 mg/kg prn sedation intervention 2: Alfentanil 10 ug/kg IV followed by 5 ug/kg prn sedation

Protocol document: