Conditions: Pain Delayed Onset Muscle Soreness
Keywords: DOMS
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 24
Healthy volunteers: yes

Brief summary:
The purpose of this study is to evaluate analgesic efficacy of Topical Voltaren Gel (diclofenac sodium gel) 1% applied QID compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness.

Detailed description:
The purpose of this randomized, double-blind, placebo controlled, within-subject study is to evaluate the efficacy of topical diclofenac sodium gel (DSG) 1% in reducing pain associated with delayed onset muscle soreness (DOMS). Following exercise, subjects reporting significant DOMS received topical DSG 1% applied to 1 leg and placebo applied to the other every 6 hours for 48 hours.

Arms:
arm 1: Diclofenac sodium 1% gel 4 grams applied topically Q6 hour for 48 hours arm 2: Placebo gel 4gm applied topically Q6 hour for 48 hours

Interventions: intervention 1: 1% diclofenac sodium gel intervention 2: Placebo
Intervention descriptions: intervention 1: Diclofenac sodium 1% gel 4 grams applied topically Q6 hour for 48 hours intervention 2: Placebo gel 4gm applied topically Q6 hour for 48 hours

Protocol document: