Conditions: Schizophrenia
Keywords: sleep schizophrenia procedural learning motor skill
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 25
Healthy volunteers: no

Brief summary:
This study will determine whether eszopiclone will normalize sleep patterns and restore sleep-dependent enhancement of motor skill learning in patients with schizophrenia. The investigators will compare subjects taking a placebo to those taking 3 mg of eszopiclone with regard to: sleep architecture and sleep latency as measured by actigraphy and polysomnography and sleep-dependent motor skill learning.

Detailed description:

Arms:
arm 1: 3mg of eszopiclone on two consecutive nights arm 2: placebo capsule that looks identical to eszopiclone capsule on two consecutive nights

Interventions: intervention 1: eszopiclone intervention 2: placebo
Intervention descriptions: intervention 1: 3 mg of eszopiclone at bedtime on two consecutive nights intervention 2: Placebo capsules looking identical to eszopiclone at bedtime on two consecutive nights

Protocol document: