Conditions: Facial Rhytides Glabellar Frown Lines
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 175
Healthy volunteers: no

Brief summary:
This study evaluated the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of forehead lines (facial rhytides) when also administered to frown lines (glabellar rhytides).

Detailed description:

Arms:
arm 1: Botulinum toxin Type A 40 Units (total dose) injected into bilateral forehead and frown line areas on Day 1. arm 2: Botulinum toxin Type A 30 Units (total dose) injected into bilateral forehead and frown line areas on Day 1. arm 3: Placebo (Normal saline) injected into bilateral forehead and frown line areas on Day 1.

Interventions: intervention 1: botulinum toxin Type A intervention 2: Normal Saline
Intervention descriptions: intervention 1: Botulinum toxin Type A (total dose 30 Units or 40 Units) injected into bilateral forehead and frown line areas on Day 1. intervention 2: Normal Saline (placebo) injected into bilateral forehead and frown line areas on Day 1.

Protocol document: