Conditions: Laryngismus
Keywords: laryngeal mask airway insertion sevoflurane remifentanil
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 102
Healthy volunteers: no

Brief summary:
The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.

Detailed description:
For practical purposes, opioids with the ability to suppress upper airway reflexes have been used to facilitate insertion of the LMA during anaesthesia induction. To date, however, there have been no published reports addressing the use of remifentanil to facilitate LMA insertion during sevoflurane inhalation induction in adults. Therefore, the purpose of this study was to determine the most suitable effect-site concentration of remifentanil target-controlled infusion (TCI) for the LMA insertion during inhaled induction with 8% sevoflurane in adults.

Arms:
arm 1: The control group, which received an infusion of normal saline. arm 2: "Remifentanil 1": "The R1 group, which received a target effect-site remifentanil concentration of 1 ng/ml. arm 3: "Remifentanil 2": "The R2 group, which received a target effect-site remifentanil concentration of 2 ng/ml.

Interventions: intervention 1: Remifentanil 1 intervention 2: Control intervention 3: Remifentanil 2
Intervention descriptions: intervention 1: "Remifentanil 1": "The R1 group, which received a target effect-site remifentanil concentration of 1 ng/ml. intervention 2: The control group, which received an infusion of normal saline intervention 3: "Remifentanil 2": "The R2group, which received a target effect-site remifentanil concentration of 2 ng/ml.

Protocol document: