Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 15
Healthy volunteers: yes

Brief summary:
The primary objective of this trial is to investigate the effect of food and of gastric pH increase on the relative bioavailability of faldaprevir.

Detailed description:

Arms:
arm 1: faldaprevir medium, fasted arm 2: faldaprevir medium, fed arm 3: faldaprevir medium + omeprazole medium

Interventions: intervention 1: faldaprevir intervention 2: faldaprevir intervention 3: omeprazole intervention 4: faldaprevir
Intervention descriptions: intervention 1: medium dose of faldaprevir intervention 2: medium dose of faldaprevir intervention 3: medium dose of omeprazole intervention 4: medium dose of faldaprevir

Protocol document: