Conditions: Macular Edema Secondary to Central Retinal Vein Occlusion
Keywords: Macular edema Retinal vein occlusion CRVO VEGF Trap-Eye best-corrected visual acuity Regeneron COPERNICUS
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 189
Healthy volunteers: no

Brief summary:
This is a phase 3 study to determine the efficacy of VEGF Trap-Eye injected into the eye on vision function in subjects with macular edema as a consequence of central retinal vein occlusion.

Detailed description:

Arms:
arm 1: Monthly IVT injection of VEGF Trap-Eye 2.0 mg until Week 24 Primary Endpoint arm 2: Monthly Sham IVT injection until Week 24 Primary Endpoint

Interventions: intervention 1: VEGF Trap-Eye 2.0mg intervention 2: Sham
Intervention descriptions: intervention 1: Monthly intravitreal injection out to the Week 24 Primary endpoint intervention 2: Monthly sham intravitreal injection out to Week 24 Primary Endpoint

Protocol document: