Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 36
Healthy volunteers: yes

Brief summary:
To investigate the relative bioavailability of ibuprofen from a (FDC) film-coated tablet of ibuprofen and caffeine vs. a tablet of ibuprofen (Brufen®) and a tablet of ibuprofen lysinate (Nurofen Immedia®).

Detailed description:

Arms:
arm 1: film-coated tablet arm 2: film-coated tablet arm 3: fixed-dose-combination (FDC)

Interventions: intervention 1: Ibuprofen+caffeine FDC intervention 2: Ibuprofen (Nurofen Immedia®) intervention 3: Ibuprofen (Brufen®)
Intervention descriptions: intervention 1: oral dose intervention 2: oral dose intervention 3: oral dose

Protocol document: