Conditions: Allergic Rhinitis Asthma Allergy
Keywords: asthma allergic rhinitis dietary interventions mouse allergy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 51
Healthy volunteers: no

Brief summary:
The primary objective of this study is to determine if broccoli sprouts (BS) improves airway inflammatory, oxidative stress (OS), and symptoms among asthmatic adults with aeroallergen sensitization.

The study is a double-blind, placebo-controlled, randomized trial to compare BS to placebo in 40 adults with asthma. 40 adults (age 18-50) who meet these eligibility criteria will be randomized to receive either: (a) BS or (b) placebo (alfalfa sprouts). Subjects will eat a sprouts sandwich daily for three days, and then undergo repeat measurement of outcomes.

Detailed description:

Arms:
arm 1: Broccoli Sprout sandwich/wrap will be eaten daily for 3 consecutive days arm 2: Alfalfa Sprouts will be eaten daily in a sandwich form for 3 consecutive days

Interventions: intervention 1: Broccoli Sprouts intervention 2: Placebo
Intervention descriptions: intervention 1: 100g of either broccoli or alfalfa sprouts will be eaten daily in a sandwich or wrap form. intervention 2: Alfalfa Sprouts

Protocol document: