Conditions: Type 2 Diabetes Mellitus
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 24
Healthy volunteers: no

Brief summary:
This study will evaluate how EFB0027 and EFB0026 behave in subjects with type 2 diabetes mellitus.

In addition, this study will compare the effects of EFB0027 and EFB0026 on circulating concentrations of glucose and gastrointestinal hormones in subjects with type 2 diabetes mellitus.

Detailed description:

Arms:
arm 1: BID arm 2: BID arm 3: BID arm 4: BID

Interventions: intervention 1: EFB0027 (metformin delayed release) intervention 2: EFB0026 (metformin immediate-release)
Intervention descriptions: intervention 1: Comparison of enteric-coating to assess effect on PK intervention 2: Active comparator

Protocol document: