Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 40
Healthy volunteers: no

Brief summary:
This study will determine if aspirin from PL2200, an investigational product, gets into the blood stream as quickly as plain aspirin and enteric coated aspirin, and to test whether PL2200 is able to prevent blood clots as effectively as these other products, when administered to patients with diabetes.

Detailed description:

Arms:
arm 1: Investigational drug arm; crossover design arm 2: Active comparator; crossover design arm 3: Active comparator; crossover design

Interventions: intervention 1: PL2200 Aspirin Capsules intervention 2: Immediate-Release Aspirin Tablets intervention 3: Enteric-coated aspirin caplets
Intervention descriptions: intervention 1: 325 mg aspirin; once per day for 3 days intervention 2: 325 mg aspirin; once per day for 3 days intervention 3: 325 mg aspirin; once per day for 3 days

Protocol document: