Conditions: Migraine
Keywords: migraine, emergency department, dexketoprofen, placebo
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 224
Healthy volunteers: no

Brief summary:
H0 hypothesis: IV dexketoprofen is equivalent to placebo in ceasing migraine attack in emergency department.

H1 hypothesis: IV dexketoprofen is not equivalent (superior) to placebo in ceasing migraine attack in emergency department.

Detailed description:
Migraine attack is one of the most leading causes presentations to emergency department. Patients with migraine attack seek urgent care to cease their pain. There are so many interventions defined in the medical literature that can be used in migraine attacks. However, as a IV drug, dexketoprofen; little known whether IV dexketoprofen is superior to placebo or not. In the present study we aimed to determine the effects of IV dexketoprofen in migraine attack in emergency department.

Arms:
arm 1: 50 mg intravenous dexketoprofen in 50 ml normal saline in 5 minutes infusion. arm 2: 50 ml normal saline

Interventions: intervention 1: Dexketoprofen intervention 2: Normal Saline
Intervention descriptions: intervention 1: 50 mg intravenous arveles in 50 ml saline in 5 minutes intervention 2: 50 ml normal saline

Protocol document: