Conditions: Eosinophilic Esophagitis
Keywords: Eosinophilic Esophagitis Cinquil
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 190
Healthy volunteers: no

Brief summary:
This study is an open-label study where all subjects will receive active drug, reslizumab. Subjects are able to enter this trial only through completion of study Res-05-0002 (NCT00538434).

The goal of the study is to show longer term safety and efficacy in pediatric subjects who have eosinophilic esophagitis.

Detailed description:
Subjects will enter this open-label extension study after completing the placebo-controlled, double-blind study Res-5-0002 (NCT00538434). The end of study visit for Res-05-0002 will serve as the screening visit for this trial.

All subjects will receive reslizumab and be followed by their principal investigators in an unblinded fashion. Visits and administration of reslizumab will be monthly.

Arms:
arm 1: Open-label reslizumab intravenous (IV) infusion at an initial dose of 1 mg/kg monthly

Interventions: intervention 1: reslizumab
Intervention descriptions: intervention 1: None

Protocol document: