Conditions: Rheumatoid Arthritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 143
Healthy volunteers: no

Brief summary:
The primary purpose of this study is to identify an appropriate dose of study medication.

Detailed description:

Arms:
arm 1: Clazakizumab Dose # A injection by subcutaneous for 12 weeks + background Methotrexate arm 2: Clazakizumab Dose # B injection by subcutaneous for 12 weeks + background Methotrexate arm 3: Clazakizumab Dose # C injection by subcutaneous for 12 weeks + background Methotrexate arm 4: Clazakizumab Dose # D injection by subcutaneous for 12 weeks + background Methotrexate

Interventions: intervention 1: Clazakizumab intervention 2: Placebo (Matching with Clazakizumab)
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: