Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 36
Healthy volunteers: yes

Brief summary:
To assess drug drug interaction through pharmacokinetics investigation at steady state of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ) given as three different formulations in healthy Japanese male subjects

Detailed description:

Arms:
arm 1: Telmisartan/Amlodipine/HCTZ fixed-dose combination arm 2: Telmisartan/Amlodipine fixed-dose combination arm 3: Telmisartan/HCTZ fixed-dose combination

Interventions: intervention 1: Telmisartan/Amlodipine intervention 2: Telmisartan/Amlodipine/HCTZ intervention 3: Telmisartan/HCTZ
Intervention descriptions: intervention 1: Telmisartan/Amlodipine fixed-dose combination intervention 2: Telmisartan/Amlodipine/HCTZ fixed-dose combination intervention 3: Telmisartan/HCTZ fixed-dose combination

Protocol document: