Conditions: Coronary Artery Disease Carotid Artery Disease Peripheral Artery Disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 9
Healthy volunteers: no

Brief summary:
This study is looking to see if niacin will lessen atherosclerotic plaque inflammation and favorably affect circulating levels of endothelial progenitor cells and microparticles in people with atherosclerotic disease on chronic statin therapy.

Detailed description:

Arms:
arm 1: Niacin titrated up to 6 grams taken orally every day for 12 weeks arm 2: Placebo taken orally every day for 12 weeks

Interventions: intervention 1: Niacin intervention 2: Placebo
Intervention descriptions: intervention 1: Niacin titrated to 6000 mg daily intervention 2: Placebo provided in the same pill quantity as niacin arm

Protocol document: