Conditions: Alzheimer's Disease
Keywords: Alzheimer's disease
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 171
Healthy volunteers: no

Brief summary:
This is a multi-center, open-label, single-arm, prospective, phase IV trial, evaluating safety and efficacy of donepezil hydrochloride in patients with moderate to severe Alzheimer's disease.

Detailed description:
This study consisted of pre-treatment and treatment phase. Pre-treatment phase was approximately 4 weeks including the screening and baseline process. In treatment phase, about 190 subjects received Donepezil HCl 23 mg once daily for 24 weeks.

Arms:
arm 1: Donepezil HCl 23 mg once daily, just before bed, for 24 weeks

Interventions: intervention 1: Donepezil HCL
Intervention descriptions: intervention 1: Donepezil HCl 23 mg once daily, just before bed, for 24 weeks

Protocol document: