Conditions: Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
Keywords: Chronic Obstructive Pulmonary Disease COPD; cachexia; muscle wasting
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 67
Healthy volunteers: yes

Brief summary:
This study will assess the pharmacodynamics, pharmacokinetics, safety and tolerability of BYM338 in patients with COPD and cachexia. The primary outcome will be a change in thigh muscle volume compared to placebo. The study will last for approximately 24 weeks.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Placebo intervention 2: BYM338
Intervention descriptions: intervention 1: None intervention 2: BYM338

Protocol document: