Conditions: Open-Angle Glaucoma Ocular Hypertension
Keywords: Glaucoma Intraocular pressure Tonometry, ocular
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 112
Healthy volunteers: no

Brief summary:
The purpose of this study was to assess patient preference regarding ocular comfort of AZARGA® compared to COSOPT® after one week instillation of each study medication.

Detailed description:
At the Screening Visit, each intervention was instilled in one eye in a contralateral fashion to establish baseline ocular comfort prior to randomization. A 48-hour washout period separated the two treatment periods.

Arms:
arm 1: 1 drop AZARGA instilled in each eye twice a day for 7 days, followed by 1 drop COSOPT instilled in each eye twice a day for 7 days. A 48-hour washout period separated the two treatment periods. arm 2: 1 drop COSOPT instilled in each eye twice a day for 7 days, followed by 1 drop AZARGA instilled in each eye twice a day for 7 days. A 48-hour washout period separated the two treatment periods.

Interventions: intervention 1: Brinzolamide 1.0% + Timolol 0.5% ophthalmic suspension intervention 2: Dorzolamide 2.0% + Timolol 0.5% ophthalmic solution
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: