Conditions: Familial Hypercholesterolemia
Keywords: pediatric heterozygous familial hypercholesterolemia
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 272
Healthy volunteers: no

Brief summary:
The purpose of this study is to characterize three year descriptive growth and development (ie, height, weight, body mass index, Tanner Stage) and efficacy of cholesterol reduction in pediatric subjects with Heterozygous Familial Hypercholesterolemia receiving atorvastatin treatment.

Detailed description:

Arms:
arm 1: All subjects will be treated with atorvastatin

Interventions: intervention 1: atorvastatin
Intervention descriptions: intervention 1: Atorvastatin tablets or chewable tablets, 5, 10, 20, 40 mg strengths, once daily, for three years (an 80 mg maximum daily dose is delivered by taking two 40 mg strengths, once daily)

Protocol document: