Conditions: Gastroesophageal Reflux Disease (GERD) Heartburn Dyspepsia
Keywords: Gastroesophageal reflux disease (GERD) Heartburn Dyspepsia
Allocation: RANDOMIZED | Intervention model: FACTORIAL
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of this study is to investigate the effects of a widely available over the counter supplement marketed for heartburn symptoms on symptoms and health-related quality of life in patients with gastroesophageal reflux disease (GERD). This study is designed as a pilot trial to assess safety and feasibility and to provide preliminary estimates of effect sizes.

Detailed description:

Arms:
arm 1: Supplement, 2 tablets sublingually 3 times a day for 2 weeks. arm 2: Placebo, 2 tablets sublingually 3 times a day for 2 weeks. arm 3: Supplement, 2 tablets sublingually 3 times a day for 2 weeks. arm 4: Placebo, 2 tablets sublingually 3 times a day for 2 weeks.

Interventions: intervention 1: Supplement intervention 2: Placebo intervention 3: Expanded Interview intervention 4: Standard Interview
Intervention descriptions: intervention 1: Abies nigra 4C, Carbo vegetabilis 4C, Nux vomica 4C, and Robinia pseudoacacia 4C intervention 2: Lactose tablets intervention 3: None intervention 4: None

Protocol document: