Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 70
Healthy volunteers: yes

Brief summary:
In this first-in-man trial, safety, tolerability, pharmacokinetics, and selected pharmacodynamics parameters of BI 1015550 will be assessed in healthy male volunteers.

Detailed description:

Arms:
arm 1: Powder for oral solution arm 2: Powder for oral solution arm 3: Powder for oral solution arm 4: Powder for oral solution arm 5: Powder for oral solution arm 6: Powder for oral solution arm 7: Powder for oral solution arm 8: Powder for oral solution arm 9: Powder for oral solution arm 10: Solution for oral administration

Interventions: intervention 1: BI 1015550 intervention 2: BI 1015550 intervention 3: BI 1015550 intervention 4: BI 1015550 intervention 5: BI 1015550 intervention 6: Placebo intervention 7: BI 101550 intervention 8: BI 1015550 intervention 9: BI 1015550 intervention 10: BI 1015550
Intervention descriptions: intervention 1: High dose powder for oral solution intervention 2: Medium dose powder for oral solution intervention 3: Low dose powder for oral solution intervention 4: Low dose powder for oral solution intervention 5: Low dose powder for oral solution intervention 6: Solution for oral administration intervention 7: High dose powder for oral solution intervention 8: Low dose powder for oral solution intervention 9: Medium dose powder for oral solution intervention 10: Medium dose powder for oral solution

Protocol document: