Conditions: Glaucoma Ocular Hypertension Open-Angle Glaucoma
Keywords: Glaucoma Ocular Hypertension Open-Angle Glaucoma Intraocular Pressure
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 84
Healthy volunteers: no

Brief summary:
The purpose of this study was to assess efficacy and tolerability of travoprost 0.004% vs. bimatoprost 0.01% during the after office hour period (4 pm to 8 pm) in subjects with open-angle glaucoma or ocular hypertension after 6 weeks of treatment.

Detailed description:

Arms:
arm 1: Travoprost 0.004% ophthalmic solution (TRAVATAN), 1 drop to the study eye once daily every evening at 8:00 pm for 6 weeks, followed by bimatoprost 0.01% ophthalmic solution (LUMIGAN), same dose, same duration, as randomized, for a total duration of 12 weeks arm 2: Bimatoprost 0.01% ophthalmic solution (LUMIGAN), 1 drop to the study eye once daily every evening at 8:00 pm for 6 weeks, followed by travoprost 0.004% ophthalmic solution (TRAVATAN), same dose, same duration, as randomized, for a total duration of 12 weeks

Interventions: intervention 1: Travoprost 0.004% ophthalmic solution intervention 2: Bimatoprost 0.01% ophthalmic solution
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: