Conditions: Healthy
Keywords: direct-to-consumer advertising
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 340
Healthy volunteers: yes

Brief summary:
The primary goal of this study is to examine determinants of the efficacy of Claritin.

Detailed description:
Subjects will be given Claritin 10mg tablet. Subjects will be challenged with histamine via skin prick prior to Claritin administration and at 1 and 2 hours post administration. We will measure and record wheal and flare area 10 minutes following each challenge.

Arms:
arm 1: Subject will be given 10mg Claritin tablet and then watch a movie that includes commercials for Claritin. arm 2: Subject will be given 10mg Claritin tablet and then watch a movie that includes commercials for Zyrtec.

Interventions: intervention 1: Claritin
Intervention descriptions: intervention 1: Subject will be given 10mg Claritin tablet.

Protocol document: