Conditions: Inguinal Hernia
Keywords: inguinal hernia infection prophylaxis topical gentamicin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 276
Healthy volunteers: no

Brief summary:
Aim of this study is to measure the effectiveness of topical gentamicin to prevent post-operative infection in inguinal tension-free hernia repair operation.Secondary aim is, if it is effective as a prophylactic agent, to compare it's effect with intra venous single dose cefazolin sodium prophylaxis.

Detailed description:
This study is a single blind prospective randomized trial. To measure and compare the effectiveness intra-operative topical gentamicin application in tension-free inguinal hernia repair in contrast to intravenous peri-operative prophylactic cefazolin sodium and combination of gentamicin and cephazolin this study is designed.

The patients are grouped randomly in to two groups:

* Group1;intravenous cefazolin sodium
* Group2;topical gentamicin
* Group3:topical gentamicin and intravenous cefazolin sodium

As a control group we decided to use the data of control groups ( without any prophylactic agent usage ) of previous studies done in our clinic and medical data base reviews.

Arms:
arm 1: 80 mg gentamicin topical application intraoperatively arm 2: Application of 1000 mg cefazolin intra venously 1 hour before surgery arm 3: 1000 mg cefazolin application 1 hour before surgery and topical 80 mg gentamicin intraoperatively

Interventions: intervention 1: Gentamicin and cefazolin intervention 2: Cefazolin intervention 3: Gentamicin
Intervention descriptions: intervention 1: 80 mg topically, intra-operative,single dose and intravenous 1000 mg cefazolin 1 hour before operation intervention 2: 1000 mg cefazolin application intravenously 1 hour before operation intervention 3: 80 mg gentamicin application intraoperatively

Protocol document: