Conditions: Insomnia Sleep Initiation and Maintenance Disorders Alzheimer Disease
Keywords: Mild Cognitive Impairment (MCI) Sleep Fatigue Memory
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 2
Healthy volunteers: no

Brief summary:
Modafinil, trade named Provigil, is a medication approved by the Food and Drug Administration for the treatment of narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder. Each of these problems is characterized by difficulty sleeping at night and excessive daytime sleepiness. Modafinil is prescribed during the day to counteract this sleepiness. The idea behind this treatment is that sleepiness that leads to napping during the day prevents a patient from being tired or sleepy enough to get good sleep at night. This study is designed to determine if the medication can "reset" participants' sleep/wake rhythm to a more normal rhythm.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: modafinil
Intervention descriptions: intervention 1: 100-400 mg daily for 4 weeks

Protocol document: