Conditions: Opioid-Induced Constipation (OIC)
Keywords: Non-Cancer-Related Pain Opioid-Induced Constipation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 844
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the long-term safety and tolerability of NKTR-118 treatment of opioid-induced constipation (OIC) in patients with non-cancer-related pain.

Detailed description:

Arms:
arm 1: Oral Treatment arm 2: Oral treatment

Interventions: intervention 1: NKTR-118 intervention 2: Usual care
Intervention descriptions: intervention 1: 25 mg oral tablet once daily intervention 2: As prescribed by the investigator

Protocol document: