Conditions: Choroidal Melanoma
Keywords: Choroidal melanoma Ranibizumab Transpupillary Thermotherapy CSTIP Indocyanine Green
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 10
Healthy volunteers: no

Brief summary:
Ranibizumab has proven to be of benefit to improve the perfusion in the retina of patients with Choroidal Melanoma. The investigators consider that higher doses of Ranibizumab can help reduce the number of laser treatments that might be needed to control the tumor.

Detailed description:

Arms:
arm 1: 6 patients will receive 3 injections of Ranibizumab (2 mg) a month apart. arm 2: 6 patients will receive 0.5 mg of Ranibizumab every two weeks per 3 months.

Interventions: intervention 1: Ranibizumab 2 mg intervention 2: 0.5 mg Ranibizumab
Intervention descriptions: intervention 1: intravitreal injections of ranibizumab once a month, times 3. intervention 2: 6 intravitreal injections of 0.5 mg Ranibizumab every 2 weeks x 3 months.

Protocol document: