Conditions: Enteral Feeding Intolerance
Keywords: Enteral feeding
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 13
Healthy volunteers: no

Brief summary:
This study is being conducted to evaluate the safety, tolerability and early efficacy of IV TD 8954 compared to metoclopramide in critically ill subjects, aged 18 to 85 years, who are admitted to the intensive care require mechanical ventilation, and are intolerant to enteral feeding.

Detailed description:

Arms:
arm 1: TD-8954 single infusion for 1 hour and 4 injections of saline every 6 hours arm 2: Metoclopramide 4 doses every 6 hours for 24 hours and 1 hour infusion of saline

Interventions: intervention 1: TD-8954 intervention 2: Metoclopramide
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: