Conditions: Dental Caries
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 55
Healthy volunteers: yes

Brief summary:
An in situ model will be used to evaluate and compare enamel remineralization of human enamel specimens after single use of experimental children's toothpastes.

Detailed description:

Arms:
arm 1: toothpaste with no fluoride arm 2: Experimental toothpaste containing 1426 ppm Fluoride arm 3: Experimental toothpaste containing 1000 ppm Fluoride arm 4: Experimental toothpaste containing 500 ppm Fluoride

Interventions: intervention 1: Fluoride intervention 2: Placebo
Intervention descriptions: intervention 1: Fluoride Toothpaste intervention 2: Fluoride free toothpaste

Protocol document: