Conditions: Pulmonary Disease, Chronic Obstructive
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 84
Healthy volunteers: no

Brief summary:
The main objective of the current trial is to investigate safety, tolerability and pharmacokinetics of BI 113608 in COPD patients with symptoms of chronic bronchitis.

Detailed description:

Arms:
arm 1: Film-coated tablet, oral administration with 240 mL water arm 2: Film-coated tablet, oral administration with 240 mL water arm 3: Film-coated tablet, oral administration with 240 mL water

Interventions: intervention 1: Placebo to BI 113608 high dose b.i.d. intervention 2: Placebo to BI 113608 low dose b.i.d. intervention 3: BI 113608 high dose b.i.d. intervention 4: Placebo to BI 113608 medium dose b.i.d. intervention 5: BI 113608 low dose b.i.d. intervention 6: BI 113608 medium dose b.i.d.
Intervention descriptions: intervention 1: Film-coated tablet intervention 2: Film-coated tablet intervention 3: Film-coated tablet intervention 4: Film-coated tablet intervention 5: Film-coated tablet intervention 6: Film-coated tablet

Protocol document: