Conditions: Acute Coronary Syndrome Percutaneous Coronary Intervention
Keywords: acute coronary syndrome coronary disease coronary artery disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 801
Healthy volunteers: no

Brief summary:
The purpose of the study is to assess the efficacy (prevention of vascular events) and safety (especially bleedings) of Ticagrelor (AZD6140) compared with Clopidogrel, both given on top of low dose aspirin, in Asian/Japanese patients with acute coronary syndrome and a planned percutaneous coronary intervention (PCI).

Detailed description:

Arms:
arm 1: Ticagrelor (AZD6140) arm 2: Clopidogrel

Interventions: intervention 1: Ticagrelor intervention 2: Clopidogrel intervention 3: Acetylsalicylic acid ASA
Intervention descriptions: intervention 1: 90 mg, oral dose twice daily intervention 2: 75 mg, oral dose once daily intervention 3: Low Dose ASA

Protocol document: