Conditions: Healthy Volunteers
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 72
Healthy volunteers: yes

Brief summary:
The purpose of this study is to evaluate the effect on the electrical activity of the heart as measured by an electrocardiogram (ECG) after dosing with 10 days of LY2484595 compared to 10 days of placebo in relation to a single dose of moxifloxacin. Information about any side effects that occur will also be collected.

Detailed description:

Arms:
arm 1: Administered orally once daily for 10 days during 1 of the 3 crossover periods, separated by at least a 14-day washout period. arm 2: Administered orally once daily for 10 days during 1 of the 3 crossover periods, separated by at least a 14-day washout period. arm 3: Positive control, unblinded treatment administered orally once during 1 of 3 crossover periods, separated by at least a 14-day washout period.

Interventions: intervention 1: LY2484595 intervention 2: Placebo intervention 3: Moxifloxacin
Intervention descriptions: intervention 1: Administered orally once daily for 10 days. intervention 2: Administered orally once daily for 10 days. intervention 3: Single dose administered orally.

Protocol document: