Conditions: Obesity Overweight
Keywords: Calcium Carbonate Vitamin D Body weight Body fat Metabolic parameters Energy restriction Very-low calcium consumers Obesity Overweight
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 53
Healthy volunteers: yes

Brief summary:
The purpose of the study is to determine whether calcium plus vitamin D supplementation is conducive to weight and fat loss during energy restriction in very-low calcium consumers.

Detailed description:
Due to the contradicting findings in the hypothesis of calcium supplementation on weight and fat loss, which might be explained by the difference in initial calcium intake, the present study is aimed to evaluate the effect of calcium plus vitamin D supplementation on accelerating weight and fat loss in overweight or obese subjects with very-low calcium consumption(\<600mg/day).

The hypotheses to be tested are:

Calcium plus vitamin D supplementation is conducive to body weight and fat loss in overweight or obese young adults during energy restriction 12 weeks after randomization.

Arms:
arm 1: Calcium supplements provide 600mg of calcium and 125IU vitamin D per day. A balanced diet contains 500kcal of caloric deficit based on daily energy expenditure. arm 2: A balanced diet contains 500kcal of caloric deficit based on daily energy expenditure.

Interventions: intervention 1: Calcium Carbonate intervention 2: Energy restriction
Intervention descriptions: intervention 1: tablet, 600mg elemental calcium and 125IU vitamin D, once daily, for 12 weeks intervention 2: A balanced diet contains 500kcal of caloric deficit based on daily energy expenditure.

Protocol document: