Conditions: Cervical Preparation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: no

Brief summary:
In this study the investigators plan to compare mifepristone and misoprostol use to osmotic dilator use for cervical preparation for 15-18 week surgical abortion. Mifepristone would be given 24 hours prior to abortion, and misoprostol 400 mcg would be administered buccally 2 hours prior to abortion. Osmotic dilators are the method currently used in our institution, and are placed 24 hours prior to abortion. The primary outcome will be the length of the procedure. Secondary outcomes will include amount of dilation achieved, ease of procedure, participant's assessment of discomfort before mifepristone or dilators, discomfort during the abortion procedure, acceptability to participants, and acceptability to staff.

Detailed description:

Arms:
arm 1: Mifepristone 200 mg PO given 20-24 hours prior to procedure, misoprostol 400 mcg given 2 hours prior to procedure arm 2: Placed 20-24 hours prior to procedure

Interventions: intervention 1: Mifepristone intervention 2: osmotic dilators
Intervention descriptions: intervention 1: 200 mg po 20-24 hours prior to the procedure intervention 2: osmotic dilators placed in the cervix 20-24 hours prior to the procedure

Protocol document: