Conditions: Iron Overload Due to Repeated Red Blood Cell Transfusions
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 30
Healthy volunteers: no

Brief summary:
The purpose of this extension study is to evaluate SSP-004184AQ in patients with transfusional iron overload and to provide data on long term safety and efficacy.

SSP-004184AQ is an iron chelator under development for chronic daily oral administration to patients with transfusional iron overload

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: SSP-004184AQ
Intervention descriptions: intervention 1: Long term extension study of 8-75 mg/kg/d of SSP-004184AQ (equivalent to 7-68 mg/kg/d free acid or "active" form)

Protocol document: