Conditions: Esophagogastroduodenoscopy
Keywords: Esophagogastroduodenoscopy Lidocaine Propofol
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 120
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine the efficacy of application of the anaesthesia topical pharyngeal with lidocaine in esophagogastroduodenoscopy under propofol´s sedation, in therms of dosage and side effect´s reduction overall.

Detailed description:

Arms:
arm 1: Blinded spraying 50 mg of pharyngeal topical lidocaine 180 seconds before sedated esophagogastroduodenoscopy (EGD) arm 2: Excipients without lidocaine. The flavour taste is the same of active comparator ensuring the masking.

Interventions: intervention 1: Lidocaine intervention 2: Placebo
Intervention descriptions: intervention 1: Applying of 5 puff controlled released (50 mg) transoral spray of lidocaine (10 mg=1 puff). intervention 2: Applying of 5 puff controlled released (50 mg) transoral spray of placebo (excipients of trade mark of lidocaine ensuring the patient masking).

Protocol document: