Conditions: Alzheimer's Disease
Keywords: ASL MRI perfusion cognition donepezil alzheimer's disease translational medicine
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 18
Healthy volunteers: no

Brief summary:
The study hypothesizes that donepezil will have a positive impact on brain blood flow deficits in subjects with memory deficits and/or mild dementia and that improvements in brain blood flow will be accompanied by improvements in memory.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Donepezil intervention 2: Placebo
Intervention descriptions: intervention 1: 5 mg tablets once daily for 7 days and then 10mg on 8th day intervention 2: matching placebo

Protocol document: