Conditions: Colorectal Cancer
Keywords: Colorectal cancer Olaparib MSI status Stage IV Measurable Colorectal Cancer Stratified by MSI Status
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 33
Healthy volunteers: no

Brief summary:
This study is being carried out to see if the new drug, olaparib (AZD2281), can effectively and safely treat advanced large bowel cancer. The primary goal of this clinical trial is to determine whether olaparib will have a beneficial effect on the patient's cancer by causing a response and increasing the time it takes for the cancer to progress.

Detailed description:

Arms:
arm 1: MSI - H arm

Interventions: intervention 1: olaparib
Intervention descriptions: intervention 1: 400 mg po bid continuously

Protocol document: