Conditions: Gout
Keywords: Hyperuricemia gout serum uric acid
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 30
Healthy volunteers: no

Brief summary:
The purpose of the study is to assess the effect of PF-06743649 in lowering serum uric acid in subjects suffering from gout following 14 days of dosing, as well as assessing safety and tolerability.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: PF-06743649 intervention 2: Placebo intervention 3: PF-06743649 intervention 4: Placebo
Intervention descriptions: intervention 1: Daily dosing (dose level 1) tablet for 14 days intervention 2: Daily dosing (tablet) for 14 days intervention 3: Daily dosing (dose level 2) tablet(s) for 14 days intervention 4: Daily dosing (tablets) for 14 days

Protocol document: