Conditions: Psoriasis Vulgaris
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 504
Healthy volunteers: no

Brief summary:
The purpose is to compare the efficacy of treatment with LEO 90100 at Week 4 to that of calcipotriol plus betamethasone dipropionate (BDP) gel at Week 8 in subjects with psoriasis vulgaris

Detailed description:

Arms:
arm 1: LEO 90100 aerosol foam, containing calcipotriol (as hydrate) 50 mcg/g and betamethasone 0.5 mg/g (as dipropionate), 60 g per can, applied once daily up to 12 weeks arm 2: Aerosol foam vehicle, 60 g per can, applied once daily for up to 12 weeks arm 3: Calcipotriol BDP gel, containing calcipotriol (as hydrate) 50 mcg/g and betamethasone 0.5 mg/g (as dipropionate), 60 g per bottle, applied once daily up to 12 weeks arm 4: Gel vehicle, 60 g per bottle, applied once daily up to 12 weeks

Interventions: intervention 1: LEO 90100 aerosol foam intervention 2: Aerosol foam vehicle intervention 3: Calcipotriol BDP gel intervention 4: Gel vehicle
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None intervention 4: None

Protocol document: