Conditions: Acne Vulgaris
Keywords: acne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 285
Healthy volunteers: no

Brief summary:
To evaluate the safety and effectiveness of 3 strengths of P005672-HCl compared to placebo for the treatment of moderate to severe facial acne vulgaris.

Detailed description:

Arms:
arm 1: One P005672-HCl 50 mg capsule and one Placebo capsule, oral administration, once daily for 12 weeks arm 2: Two P005672-HCl 50mg capsules, oral administration, once daily for 12 weeks arm 3: Two P005672-HCl 100mg capsules, oral administration, once daily for 12 weeks arm 4: Two Placebo capsules matching P005672-HCl, oral administration, once daily for 12 weeks

Interventions: intervention 1: 50 mg P005672-HCl intervention 2: Placebo intervention 3: 100 mg P005672-HCl
Intervention descriptions: intervention 1: P005672-HCl administered as an oral capsule(s) once daily intervention 2: Dose-matched Placebo capsule administered as an oral capsule(s) once daily intervention 3: P005672-HCl administered as an oral capsule(s) once daily

Protocol document: