Conditions: Orthostatic Hypotension
Keywords: Symptomatic Orthostatic Hypotension
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether midodrine works against the symptoms of orthostatic hypotension caused by being on a tilt table.

Detailed description:
The efficacy of midodrine will be assessed in those subjects who have severe symptoms of orthostatic hypotension when not taking midodrine and are controlled when taking midodrine. The study will involve approximately 4 overnight stays.

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Midodrine HCl intervention 2: Placebo
Intervention descriptions: intervention 1: dose at the subject's current dose level intervention 2: single dose of matching placebo

Protocol document: