Conditions: Gout
Keywords: Gout Uric Acid Xanthine oxidase Febuxostat
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 504
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare febuxostat allopurinol in subjects with gout.

Detailed description:
A randomized, double-blind, multicenter, allopurinol-controlled and parallel-assigned study comparing 40 mg, 80 mg of febuxostat, and allopurinol 300 mg in subjects with gout. Subjects will receive treatment for 24 weeks.

Arms:
arm 1: Febuxostat 40 mg, orally, once daily for up to 24 weeks arm 2: Febuxostat 80 mg, orally, once daily for up to 24 weeks arm 3: Allopurinol 100mg, orally, three times daily for up to 24 weeks

Interventions: intervention 1: Febuxostat intervention 2: Allopurinol
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: