Conditions: Obesity Binge Eating
Keywords: Obesity Binge eating Sibutramine Self-help Primary care
Allocation: RANDOMIZED | Intervention model: FACTORIAL
Enrollment: 104
Healthy volunteers: yes

Brief summary:
This study will test the effectiveness of two empirically-supported but distinct treatments for recurrent binge eating in obese patients: 1) Cognitive Behavior Therapy, using a pure self-help approach and 2) sibutramine, an anti-obesity medication also found to have efficacy for binge eating. Self-help Cognitive Behavior Therapy and sibutramine will be administered alone and in combination in a primary care setting.

Detailed description:

Arms:
arm 1: Sibutramine 15 mg daily arm 2: Placebo Daily arm 3: Placebo and Self-help CBT Placebo daily, Cognitive behavioral self-help manual for binge eating arm 4: Sibutramine and Self-help CBT 15 mg daily Cognitive behavioral treatment manual for binge eating

Interventions: intervention 1: Sibutramine intervention 2: Placebo intervention 3: Self-help CBT + Sibutramine intervention 4: Self-help CBT + Placebo
Intervention descriptions: intervention 1: 15 mg daily intervention 2: Daily intervention 3: Cognitive behavioral treatment manual for binge eating Sibutramine 15 mg daily intervention 4: Cognitive behavioral treatment manual for binge eating Placebo daily

Protocol document: