Conditions: Mild Cognitive Impairment Alzheimer's Disease
Keywords: Mild Cognitive Impairment Positron Emission Tomography National Institute of Neurological and Communicative Disorders and Stroke Alzheimer's Disease and Related Disorders Association Assess Prognostic Usefulness of Flutemetamol Injection for Identifying Subjects who will Convert to Clinically Probable Alzheimer's Disease
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 365
Healthy volunteers: no

Brief summary:
This study will investigate the efficacy of the Flutemetamol (18F) Injection PET tracer in identifying abnormal (18F) flutemetamol uptake patterns which predict the conversion from aMCI to a b-amyloid associated clinically probable Alzheimer's disease.

Detailed description:

Arms:
arm 1: Flutemetamol (18F) Injection

Interventions: intervention 1: Flutemetamol (18F) Injection
Intervention descriptions: intervention 1: All subjects will receive an i.v. dose of (18F) flutemetamol (less than 10 mg flutemetamol). The nominal activity of a single administration of (18F) flutemetamol will be 185 MBq.

Protocol document: