Conditions: Fragile X-Associated Tremor/Ataxia Syndrome Fragile X Premutation Carriers
Keywords: FXTAS, Fragile X Premutation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 94
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine if memantine is effective in treating symptoms of Fragile X-associated Tremor Ataxia Syndrome.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Memantine intervention 2: Placebo
Intervention descriptions: intervention 1: Week 1: Take 5mg tab every morning. Week 2: Take 5mg tab every morning and evening. Week 3: Take 10mg tab in the morning and 5 mg in the evening. Week 4: Take 10 mg tab in the morning and evening, and remain on this dose through the remainder of the study. intervention 2: Week 1: Take 5mg tab every morning. Week 2: Take 5mg tab every morning and evening. Week 3: Take 10mg tab in the morning and 5 mg in the evening. Week 4: Take 10 mg tab in the morning and evening, and remain on this dose through the remainder of the study.

Protocol document: