Conditions: Healthy
Keywords: central veins thorax superior vena cava Central vein imaging
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 30
Healthy volunteers: yes

Brief summary:
The purpose of this study is to assess the image quality of Ablavar-enhanced MR angiography of the central veins of the chest, and to determine whether dose reduction can be performed while maintaining image quality. This will be a prospective randomized study, in which healthy volunteers will be recruited to undergo a central veins magnetic resonance angiogram (MRA). They will receive either the FDA-approved dose or a lower dose of Ablavar. Quantitative and qualitative analysis will be performed on the images.

Detailed description:

Arms:
arm 1: FDA-approved dose for lower extremity arterial imaging arm 2: None arm 3: None

Interventions: intervention 1: gadofosveset
Intervention descriptions: intervention 1: Intravenous administration of the specified dosage of gadolinium contrast agent

Protocol document: