Conditions: Severe Hypertriglyceridemia
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 30
Healthy volunteers: no

Brief summary:
This is a randomized, open-label crossover study. The primary objective of this study is to compare the relative bioavailability of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA), and the ethyl esters of EPA and DHA in plasma from a single 2 g or 4 g dose of Epanova® or 4 g Lovaza®.

Detailed description:

Arms:
arm 1: Crossover Sequence arm 2: Crossover Sequence arm 3: Crossover Sequence arm 4: Crossover Sequence

Interventions: intervention 1: Epanova intervention 2: Lovaza
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: