Conditions: Smoking Cessation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 603
Healthy volunteers: no

Brief summary:
In smokers who are motivated to stop smoking, treatment with lorcaserin compared with placebo will provide greater abstinence as measured by the last 4 weeks of treatment (Weeks 9-12). The target quit date was Day 15.

Detailed description:

Arms:
arm 1: APD356 - lorcaserin hydrochloride 10 mg tablet administered twice daily for 12 weeks arm 2: APD356 - lorcaserin hydrochloride 10 mg tablet administered once daily and one matching placebo tablet administered once daily for 12 weeks arm 3: Placebo tablet matching the APD356-lorcaserin hydrochloride 10 mg tablet administered twice daily for 12 weeks

Interventions: intervention 1: APD356-lorcaserin hydrochloride intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: