Conditions: Dental Plaque and Gingivitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 162
Healthy volunteers: yes

Brief summary:
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.

Detailed description:

Arms:
arm 1: 1450 ppm Fluoride toothpaste arm 2: 1450 ppm sodium fluoride toothpaste with a zinc base arm 3: 1450 ppm sodium fluoride/triclosan toothpaste

Interventions: intervention 1: Control toothpaste intervention 2: Experimental toothpaste intervention 3: Active Comparator
Intervention descriptions: intervention 1: 1450 ppm fluoride toothpaste control - Subjects will brush their whole mouth with the control toothpaste 2 times/day for 1 minute each time and rinse with water after brushing. This daily brushing routine will continue for the six (6) month study. intervention 2: 1450 ppm sodium fluoride/zinc base toothpaste - Subjects will brush their whole mouth with a fluoride/zinc toothpaste 2 times/day for 1 minute each time and rinse with water after brushing. This daily brushing routine will continue for the six (6) month study. intervention 3: 1450 ppm sodium fluoride/triclosan toothpaste - Subjects will brush their whole mouth with this toothpaste 2 times/day for 1 minute each time and rinse with water after brushing. This daily brushing routine will continue for the six (6) month study.

Protocol document: