Conditions: Healthy
Keywords: HSV Herpes volunteers drug-drug interaction transplant
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 26
Healthy volunteers: yes

Brief summary:
ASP2151 is an experimental treatment for herpes. Patients undergoing organ and tissue transplantation may be prescribed ciclosporin to suppress their immune system to give the transplant an increased chance of not being rejected. A patient with a compromised immune system is more susceptible to infections such as herpes, which will require treatment.

Detailed description:

Arms:
arm 1: ASP2151 400mg + 100mg ciclosporin arm 2: ASP2151 1200mg + 100mg ciclosporin

Interventions: intervention 1: ASP2151 400mg + 100mg ciclosporin intervention 2: ASP2151 1200mg + 100mg ciclosporin
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: