Conditions: Cocaine Dependence Cocaine Withdrawal
Keywords: cocaine dependence cocaine withdrawal
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 32
Healthy volunteers: no

Brief summary:
This study examines whether carvedilol prolongs abstinence in recently abstinent cocaine dependent participants.

Detailed description:

Arms:
arm 1: None arm 2: controlled release carvedilol (Coreg CR) at 80 mg/day in once daily dosing

Interventions: intervention 1: controlled release carvedilol intervention 2: Placebo
Intervention descriptions: intervention 1: carvedilol (Coreg CR) 80 mg/day in once daily dosing for 12 weeks followed by a 2-week taper intervention 2: Placebo

Protocol document: