Conditions: Diabetes Mellitus, Type 1
Keywords: type 1 diabetes mellitus diabetes mellitus type 1 type 1 diabetes diabetes mellitus diabetes
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 88
Healthy volunteers: no

Brief summary:
The purpose of this study is to optimize several multi-dose regimens of otelixizumab, determine the highest biologically active dose, evaluate biomarkers and surrogates of efficacy, and to evaluate the effects of each multi-dose regimen of otelixizumab against standard safety and efficacy parameters.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Otelixizumab
Intervention descriptions: intervention 1: Infusion

Protocol document: