Conditions: Advanced Breast Cancer Metastatic Breast Cancer
Keywords: oncology cancer breast cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 143
Healthy volunteers: no

Brief summary:
This study will assess the relationship between fulvestrant dose and efficacy, and determine the dosing regimen as a second line therapy for Japanese postmenopausal women with oestrogen receptor positive advanced breast cancer.

Detailed description:

Arms:
arm 1: Fulvestrant 250 mg intramuscular injection arm 2: Fulvestrant 250mg (Plus 250mg Loading Regimen) arm 3: Fulvestrant 500 mg

Interventions: intervention 1: Fulvestrant intervention 2: Fulvestrant
Intervention descriptions: intervention 1: 250 intramuscular injection intervention 2: 500 mg intramuscular injection

Protocol document: