Conditions: Tobacco Use Disorder
Keywords: tobacco smoking cessation nicotine dependence
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 58
Healthy volunteers: yes

Brief summary:
The investigators propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC). PTSC includes 8 weekly individual counseling sessions and use of nicotine lozenge for 12 weeks. The investigators will test the feasibility and preliminary efficacy of the intervention (i.e., cigarettes per day and prolonged abstinence).

Detailed description:
In this Stage I Behavioral \& Integrative Treatment Development (R34) project, we propose to develop a theory-based smoking cessation intervention (called Persistence-targeted smoking cessation; PTSC). PTSC includes 8 weekly individual counseling sessions and use of nicotine lozenge for 12 weeks. We will test the feasibility and preliminary efficacy of the intervention (i.e., cigarettes per day and prolonged abstinence). We hope to develop a feasible psychosocial treatment for use in a later randomized controlled trial.

Arms:
arm 1: Persistence Targeted Smoking Cessation - 8 weeks counseling + 12 weeks nicotine lozenge arm 2: Clearing the Air Smoking Cessation intervention - 8 weeks counseling + 12 weeks nicotine lozenge

Interventions: intervention 1: Persistence Targeted Smoking Cessation intervention 2: Clearing The Air intervention 3: Nicotine lozenge
Intervention descriptions: intervention 1: 8-weeks of smoking cessation counseling ("Persistence Targeted Smoking Cessation") intervention 2: 8-weeks counseling + 12-weeks nicotine lozenge based on NCI protocol, Clearing The Air intervention 3: 12-weeks 4mg nicotine lozenge

Protocol document: