Conditions: Bowel Preparation for Colonoscopy
Keywords: Colonoscopy Bowel Preparation MiraLAX Gatorade PEG-3350 MoviPrep SUPREP Chicago Bowel Preparation Scale Boston Bowel Preparation Scale
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1079
Healthy volunteers: yes

Brief summary:
The purpose of this investigation is to compare 3 versions of MiraLAX/Gatorade, MoviPrep and SUPREP to see which preparation cleanses the colon best and which preparation is best tolerated.

Detailed description:

Arms:
arm 1: MiraLAX 306 g and Gatorade 64 oz (1/2 gallon) consumed the day-prior to the colonoscopy as follows: Miralax 51 g at 12 noon; Gatorade 64 oz mixed with Miralax 255 g from about 6 PM to 9 PM arm 2: MiraLAX 357 g and Gatorade 64 oz (1/2 gallon) consumed the day-prior to the colonoscopy as follows: Miralax 68 g at 12 noon; Gatorade 64 oz mixed with Miralax 289 g from about 6 PM to 9 PM. arm 3: MiraLAX 306 g and Gatorade 64 oz (1/2 gallon) consumed as a split-dose as follows: Gatorade 32oz mixed with Miralax 153 g from about 6 PM to 8 PM the day prior to the colonoscopy; Gatorade 32oz mixed with Miralax 153 g from about 2-4 hours prior to the colonoscopy. arm 4: MoviPrep consumed as a split-dose as follows: MoviPrep 1 liter consumed from about 6 PM to 7 PM the day prior to the colonoscopy followed by 0.5 liter of clear liquids; MoviPrep 1 liter consumed from 3-4 hours prior to the colonoscopy followed by 0.5 liter of clear liquids. arm 5: SUPREP consumed as a split-dose as follows: SUPREP 16 oz consumed from about 6 PM to 7 PM the day prior to the colonoscopy followed by 32 oz of clear liquids; SUPREP 16 oz consumed from 3-4 hours prior to the colonoscopy followed by 32 oz of clear liquids.

Interventions: intervention 1: MiraLAX intervention 2: Gatorade intervention 3: MoviPrep intervention 4: SUPREP
Intervention descriptions: intervention 1: MiraLAX consumed as described in each arm. intervention 2: Gatorade consumed as described in each arm. intervention 3: MoviPrep consumed as described in each arm. intervention 4: SUPREP consumed as described in each arm.

Protocol document: