Conditions: Healthy Volunteers
Keywords: Healthy volunteers, pharmacokinetic, inhalation
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 34
Healthy volunteers: yes

Brief summary:
Relative bioavailability study to compare inhalation of Terbutaline Sulphate 1,5mg via current version of Turbuhaler with inhalation via a new version

Detailed description:
An Open-label, Single-dose, 2-period Cross over Study in Healthy Male and Female Volunteers to Assess Relative Bioavailability of Terbutaline Sulphate 1.5 mg after Inhalation via the M3 Turbuhaler (New Version) Compared with the M2 Turbuhaler (Current Version)

Arms:
arm 1: 0.4 mg terbutaline sulphate (delivered dose) per inhalation arm 2: 0.5 mg terbutaline sulphate (metered dose) per inhalation

Interventions: intervention 1: terbutaline sulphate delivered dose intervention 2: terbutaline sulphate metered dose
Intervention descriptions: intervention 1: 0.4 mg terbutaline sulphate (delivered dose) per inhalation intervention 2: 0.5 mg terbutaline sulphate (metered dose) per inhalation

Protocol document: