Conditions: Malaria
Keywords: acute malaria, KAF156
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 43
Healthy volunteers: no

Brief summary:
This study will assess efficacy, safety , tolerability and PK in uncomplicated adult malaria patients with P. vivax or P. falciparum infection after 3 day dosing with KAF156 at 400 mg/day (Part 1) and single dosing with KAF156 at 800mg (Part 2)

Detailed description:

Arms:
arm 1: Participants with Plasmodium vivax malaria received KAF156 400 mg once a day for three days. arm 2: Participants with Plasmodium falciparum malaria received KAF156 400mg once a day for three days. arm 3: Participants with Plasmodium falciparum malaria received a single dose of KAF156 800mg.

Interventions: intervention 1: KAF156
Intervention descriptions: intervention 1: KAF156 was supplied as tablets for oral use.

Protocol document: