Conditions: Hypertension
Keywords: hypertension, LCZ696, olmesartan
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 376
Healthy volunteers: no

Brief summary:
This study will assess the efficacy and safety of LCZ696 in comparison to olmesartan in essential hypertensive patients not adequately responsive to olmesartan

Detailed description:

Arms:
arm 1: Patients will be treated with one LCZ696 200 mg tablet and one placebo of olmesartan 20 mg capsule once daily for 8 weeks. arm 2: Patients will be treated with one placebo of LCZ696 200 mg tablet and one olmesartan 20 mg capsule once daily for 8 weeks.

Interventions: intervention 1: LCZ696 intervention 2: Olmesartan intervention 3: Placebo of LCZ696 intervention 4: Placebo of Olmesartan
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None intervention 4: None

Protocol document: