Conditions: Arthritis Pain Cognitive Impairment
Keywords: Pain Analgesia Cognitive impairment Randomized controlled trial Physical function
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 25
Healthy volunteers: no

Brief summary:
To compare the efficacy of long-acting oxycodone to extended-release acetaminophen in older persons with no and mild to moderate cognitive impairment and persistent moderate or higher intensity non-cancer lower extremity arthritis pain; and Describe the association of change in non-cancer pain self-report with an older adults functional status (BPI and WOMAC and brief physical performance measure) and to determine if cognitive status modifies this relationship.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: long acting oxycodone intervention 2: extra strength acetaminophen
Intervention descriptions: intervention 1: 10mg twice daily intervention 2: 1,000 mg twice daily

Protocol document: