Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 607
Healthy volunteers: no

Brief summary:
This trial compare the use of two different doses of Empagliflozin to placebo, in T2DM patients on 16 wks linagliptin treatment and metformin background therapy.

Detailed description:

Arms:
arm 1: 5 mg once daily arm 2: 1 tablet once daily arm 3: 1 tablet once daily

Interventions: intervention 1: Linagliptin intervention 2: Empagliflozin + Linagliptin intervention 3: Empagliflozin + Linagliptin intervention 4: Empagliflozin + Linagliptin intervention 5: Empagliflozin placebo + Linagliptin placebo intervention 6: Empagliflozin + Linagliptin
Intervention descriptions: intervention 1: tablet intervention 2: Fixed dose combination. intervention 3: Fixed dose combination intervention 4: Fixed dose combination intervention 5: Matching Empagliflozin + Linagliptin low dose intervention 6: Fixed dose combination.

Protocol document: