Conditions: Insulin Sensitivity
Keywords: vitamin D deficiency, insulin sensitivity
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: yes

Brief summary:
Healthy subjects with low Vitamin D levels will be randomly assigned to either Vitamin D replacement or placebo for a period of 8 weeks. Insulin sensitivity will be measured before and after the intervention, and the changes will be compared between the two groups. This will help us understand if Vitamin D replacement improves insulin sensitivity. Serum Retinol Binding Protein 4 levels will also be measured to see if changes in insulin sensitivity are mediated by RBP4.

Detailed description:

Arms:
arm 1: ERgocalcifoerol 50,000 units q weekly for 8 weeks arm 2: None

Interventions: intervention 1: Ergocalciferols intervention 2: Placebo
Intervention descriptions: intervention 1: ERgocaclciferol 50,000 units weekly for 8 weeks intervention 2: matching placebo

Protocol document: