Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 36
Healthy volunteers: yes

Brief summary:
The primary objective of this trial is to establish bioequivalence of two FDC tablets and the single tablets when administered together after a high fat high caloric meal.

Detailed description:

Arms:
arm 1: fixed dose combination tablet arm 2: empagliflozin tablets and metformin tablet arm 3: fixed dose combination tablet arm 4: empagliflozin tablet and metformin tablet

Interventions: intervention 1: Empagliflozin intervention 2: Empagliflozin + Metformin intervention 3: Metformin intervention 4: Metformin intervention 5: Empagliflozin + Metformin intervention 6: Empagliflozin
Intervention descriptions: intervention 1: empagliflozin tablets and metformin tablet intervention 2: fixed dose combination tablet (low) intervention 3: empagliflozin tablets and metformin tablet intervention 4: empagliflozin tablet and metformin tablet intervention 5: fixed dose combination tablet (low) intervention 6: empagliflozin tablet and metformin tablet

Protocol document: