Conditions: Diabetes
Keywords: Diabetes
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 60
Healthy volunteers: no

Brief summary:
This study will assess the effect of direct renin inhibition on nerve function in persons with diabetes using a double-blind, placebo-controlled randomized trial involving two treatment arms (i.e., \[1\] 30 participants enrolled and randomized to 300 mg of Aliskiren; \[2\] 30 participants enrolled and randomized to placebo).

Detailed description:

Arms:
arm 1: Pill, 300 mg, once daily, for 6 weeks arm 2: None

Interventions: intervention 1: Aliskiren intervention 2: Placebo
Intervention descriptions: intervention 1: Pill, 300 mg, once daily, for 6 weeks intervention 2: Placebo orally one tablet once a day for 6 weeks.

Protocol document: