Conditions: Malignant Pleural Mesothelioma
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 89
Healthy volunteers: no

Brief summary:
This research is being done to find out if pemetrexed and cisplatin work better when given together with an experimental drug called MORAb-009 in patients with malignant pleural mesothelioma.

Detailed description:

Arms:
arm 1: Pemetrexed, Cisplatin and MORAb-009 (Amatuximab)

Interventions: intervention 1: MORAb-009 (Amatuximab) intervention 2: Pemetrexed intervention 3: Cisplatin
Intervention descriptions: intervention 1: MORAb-009 (Amatuximab) by IV on Days 1 and 8 every 21 days for 6 cycles. intervention 2: Pemetrexed 500 mg/m2 on Day 1 of each 21-day cycle for 6 cycles intervention 3: Cisplatin 75 mg/m2 on Day 1 of each 21-day cycle for 6 cycles

Protocol document: