Conditions: Percutaneous Coronary Intervention
Keywords: Dual antiplatelet therapy clopidogrel percutaneous coronary intervention
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1010
Healthy volunteers: no

Brief summary:
1010 patients post stenting were enrolled to receive Plavix more than 12 months and less than that and rate of bleeding, complication and major cardiovascular adverse events ( MACE) were compared to evaluate safety and feasibility of long term Plavix therapy post stenting.

Detailed description:
1010 patients from registry of angioplasty and stenting in Shiraz and Baghiatolah hospital were enrolled and long term Plavix therapy more than and less than 12 months were compared between two groups of patients prospectively and rate of major adverse cardiovascular events ( MACE) (death, myocardial infarction, cerebrovascular accidents and revascularization) and rate of bleeding were compared between 2 groups.Syntax score and American heart association ( AHA) score of coronary involvement were measured and MACE was compared to these scores.

Arms:
arm 1: taking plavix more than 12 months arm 2: taking plavix less than 12 months

Interventions: intervention 1: plavix intervention 2: plavix
Intervention descriptions: intervention 1: taking plavix more than 12 months intervention 2: taking plavix less than 12 months

Protocol document: