Conditions: Atrial Fibrillation Persistent Common Pulmonary Vein
Keywords: Pulmonary Vein Isolation Adenosin effect Atrial fibrillation ablation
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 378
Healthy volunteers: no

Brief summary:
The investigators studied the effects of adenosine on the reconnection rate after successful pulmonary veins isolation by radiofrequency catheter ablation in patients with drug-resistant atrial fibrillation

Detailed description:
Pulmonary vein isolation has emerged as an effective therapy for paroxysmal atrial fibrillation. However, atrial fibrillation recurs in up to 50% of patients, generally because of recovery of pulmonary vein conduction.

Adenosine given during the initial procedure may reveal dormant pulmonary vein conduction, thereby identifying the need for additional ablation, leading to improved outcomes.

Arms:
arm 1: single arm study

Interventions: intervention 1: Adenosine arm
Intervention descriptions: intervention 1: After pulmonary vein isolation,20mg Intracardiac adenosine will be given to treatment group, will evaluate pulmonary vein reconnection.

Protocol document: