Conditions: Hypertension
Keywords: Drug Therapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 121
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effect of febuxostat, once daily (QD), compared to placebo on lowering ambulatory 24-hour mean blood pressure of participants with hypertension and hyperuricemia (not associated with gout).

Detailed description:
This study is designed to evaluate the effect of febuxostat during 6 weeks of treatment.

Arms:
arm 1: Febuxostat 80 mg, tablets, orally, once daily for up to 6 weeks. arm 2: Febuxostat placebo-matching tablets, orally, once daily for up to 6 weeks.

Interventions: intervention 1: Febuxostat intervention 2: Placebo
Intervention descriptions: intervention 1: Febuxostat 80 mg, tablets, orally, once daily for up to 6 weeks intervention 2: Febuxostat placebo-matching tablets, orally, once daily for up to 6 weeks.

Protocol document: