Conditions: Colonoscopy Preparation
Keywords: Bowel Evacuation Colonoscopy Preparation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 55
Healthy volunteers: yes

Brief summary:
The purpose of the study is to determine the efficacy of 2 regimens of lactulose as a preparation for colonoscopy.

Detailed description:
A full-dose regimen of lactulose for oral solution, where all dosing is completed the evening prior to the colonoscopy procedure, will be studied and compared to a split-dose regimen, where three doses are taken on the prior evening, and one dose is taken the morning of the procedure.

Arms:
arm 1: Four hourly doses of lactulose for oral solution are taken in the evening. The colonoscopy is initiated prior to noon on the following day. arm 2: Four hourly doses of lactulose for oral solution are taken in the evening. The colonoscopy is initiated after noon on the following day. arm 3: Three hourly doses of lactulose for oral solution are taken in the evening prior to the day of the colonoscopy procedure; one dose is taken on the morning of the procedure. The colonoscopy is initiated prior to noon. arm 4: Three hourly doses of lactulose for oral solution are taken in the evening prior to the day of the colonoscopy procedure; one dose is taken on the morning of the procedure. The colonoscopy is initiated after noon.

Interventions: intervention 1: Full dose preparation intervention 2: Split dose preparation
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: