Conditions: Healthy Volunteers
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: yes

Brief summary:
The main purpose of this study is to look at the effect of evacetrapib on pravastatin levels in the blood when both drugs are taken at the same time. The study will also assess how well the body handles evacetrapib and pravastatin when given at the same time.

This study has two periods in fixed order. Each participant will enroll in both periods. This study will last approximately 25 days, not including screening.

Detailed description:

Arms:
arm 1: Single 40 milligram (mg) oral dose of pravastatin administered on Day 1. arm 2: Oral doses of 130 mg evacetrapib administered once daily on Days 2 through 11, with a single oral dose of 40 mg pravastatin coadministered on Day 11.

Interventions: intervention 1: Evacetrapib intervention 2: Pravastatin
Intervention descriptions: intervention 1: Administered orally intervention 2: Administered orally

Protocol document: