Conditions: Restless Legs
Keywords: IV Iron Restless Legs Syndrome RLS Iron
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: no

Brief summary:
Double-blind, placebo-controlled, entitled: "Intravenous Iron Metabolism in Restless Legs Syndrome

Detailed description:
To determine the effects of high-dose infusions of iron on Restless Legs Syndrome (RLS) symptoms and brain concentrations of iron.

Arms:
arm 1: Intravenous iron (FCM) arm 2: normal saline

Interventions: intervention 1: Ferric Carboxymaltose (FCM) intervention 2: Placebo
Intervention descriptions: intervention 1: 500mg FCM in 250cc normal saline (NS) IV over one hour, once on Day 3, once on Day 4 intervention 2: 250cc normal saline (NS) IV over one hour, once on Day 3, once on Day 4

Protocol document: