Conditions: Hypertension
Keywords: Food effect, hypertension, aliskiren
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 589
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effect of food on aliskiren's efficacy, pharmacokinetics and safety following an oral dose of 300 mg, given once daily under light meal versus fasted conditions.

Detailed description:

Arms:
arm 1: Aliskiren 300 mg once daily, taken 30 minutes after start of light breakfast arm 2: Aliskiren 300 mg once daily taken after after an overnight fast

Interventions: intervention 1: Aliskiren
Intervention descriptions: intervention 1: Aliskiren 300 mg once daily

Protocol document: