Conditions: Coronary Artery Stenosis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 57
Healthy volunteers: no

Brief summary:
To compare Iopamidol injection 370 and Iodixanol 320 in evaluating Neutrophil Gelatinase-Associated Lipocalin (NGAL) in patients with moderate fall in eGFR

Detailed description:
This is a pilot study having a randomized, double-blind parallel group comparison of two iodinated contrast agents used during percutaneous coronary intervention (PCI). All patients enrolled must have eGFR greater than or equal to 30 mL/min and less than or equal to 59 mL/min. Statistical summaries will be presented to analyze the various lab tests results for the two groups.

Arms:
arm 1: Non-ionic low-osmolar iodinated contrast media arm 2: Non-ionic iso-osmolar iodinated contrast media comparator

Interventions: intervention 1: Iopamidol intervention 2: Iodixanol-320
Intervention descriptions: intervention 1: Iopamidol 370, one time administration for percutaneous coronary intervention intervention 2: Iodixanol-320 single administration for percutaneous coronary intervention procedure

Protocol document: