Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 72
Healthy volunteers: yes

Brief summary:
To investigate the steady state pharmacokinetics of different formulation of Telmisartan, Amlodipine, and Hydrochlorothiazide (HCTZ).

Detailed description:

Arms:
arm 1: Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg fixed dose combination tablet arm 2: Telmisartan 80 mg/Hydrochlorothiazide 12.5 mg fixed dose combination tablet and Amlodipine 5 mg capsule

Interventions: intervention 1: Amlodipine 5mg capsule intervention 2: T80/H12.5 mg FDC tablet intervention 3: T80/A5/H12.5 mg FDC tablet
Intervention descriptions: intervention 1: Amlodipine 5mg capsule intervention 2: Telmisartan 80 mg/Hydrochlorothiazide 12.5 mg FDC tablet intervention 3: Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg FDC tablet

Protocol document: