Conditions: Diabetes Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 368
Healthy volunteers: no

Brief summary:
This trial is conducted in Asia. The aim of this trial is to investigate the efficacy and safety of liraglutide compared to sitagliptin, both as add-on to metformin in Chinese subjects with type 2 diabetes inadequately controlled on metformin monotherapy. Eligible subjects will continue their metformin background treatment during the trial.

Detailed description:

Arms:
arm 1: 2-week screening period, 26-week treatment duration, and a 1-week follow-up period arm 2: 2-week screening period, 26-week treatment duration, and a 1-week follow-up period

Interventions: intervention 1: liraglutide intervention 2: sitagliptin
Intervention descriptions: intervention 1: Administered subcutaneously (s.c., under the skin) once daily as add-on to the subject's stable pre-trial metformin dose. intervention 2: Administered orally once daily as add-on to the subject's stable pre-trial metformin dose.

Protocol document: