Conditions: Shock
Keywords: hypovolemic or septic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 11
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the effectiveness of high doses of Vitamin C in critically ill patients.

Detailed description:
It has been shown that the stress that occurs during trauma, infection and/or shock depletes many of the body's resources such as Vitamin C (ascorbic acid) which may contribute to further complications. The purpose of this study is to determine the effectiveness of high doses of Vitamin C in critically ill patients.

Arms:
arm 1: Ascorbic Acid arm 2: Ringers Lactate or Normal Saline

Interventions: intervention 1: Ascorbic Acid intervention 2: Ringers Lactate or Normal Saline
Intervention descriptions: intervention 1: 66mg/kg/hour of peripheral intravenous Vitamin C infusion for 24 hour duration, maximum total of 200 grams intervention 2: Fluid resuscitation will be given with NS or LR to achieve a same mean urine output of 0.5cc/kg/hour.

Protocol document: