Conditions: Heart Failure Elevated Serum Uric Acid
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 253
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether allopurinol is effective in relieving symptoms of patients with heart failure and high blood uric acid levels.

Detailed description:

Arms:
arm 1: Allopurinol 300 mg daily for one week, then 600 mg daily to complete 24 weeks. arm 2: Matching placebo 300 mg daily for one week, then 600 mg daily to complete 24 weeks.

Interventions: intervention 1: allopurinol intervention 2: sugar pill
Intervention descriptions: intervention 1: Allopurinol 300 mg daily for one week, then 600 mg daily to complete 24 weeks. intervention 2: Matching placebo 300 mg daily for one week, then 600 mg daily to complete 24 weeks.

Protocol document: