Conditions: Primary Open Angle Glaucoma
Keywords: primary open angle glaucoma retinal oximetry
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 14
Healthy volunteers: yes

Brief summary:
Glaucoma is the second leading cause of blindness among seniors in Canada. It is often associated with an elevated intraocular pressure (IOP), but its exact mechanism is still largely unknown. Some studies have shown a link between glaucoma and changes in the amount of oxygen in the veins of the eye. The study aims to compare the amount of oxygen in ocular veins among three different groups using a spectrophotometer. This instrument is linked to a camera and can measure the quantity of oxygen in the veins using different characteristics of the blood inside.

The groups of the study are: patients without glaucoma, patients suspected of glaucoma and patients newly diagnosed with glaucoma. The drug the investigators are using, Travoprost 0.004%, will only be administered to the groups suspected or diagnosed with glaucoma. Travoprost 0.004% is already approved for use in Quebec and is part of standard care. Ten patients will be recruited into each group for a total of 30 patients in this study. All patients for the suspected or diagnosed groups will be recruited from the Jewish General Hospital. Subsequently all testing will be done at the École d'optométrie, Université de Montréal

Detailed description:

Arms:
arm 1: Normal patient placebo arm 2: Patients with elevated Intraocular pressure higher than 18 mmHg (placebo) arm 3: Treated with Travoprost (0.04%)

Interventions: intervention 1: placebo intervention 2: travoprost
Intervention descriptions: intervention 1: Placebo intervention 2: Travatan Z is administered to newly diagnosed glaucoma patient

Protocol document: