Conditions: Colorectal Cancer
Keywords: Metastatic Colorectal Cancer RECENTIN
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1814
Healthy volunteers: no

Brief summary:
The purpose of this study is to see if Cediranib in combination with FOLFOX is effective in treating metastatic colorectal cancer and to see how it compares with Avastin (Bevacizumab) in combination with FOLFOX.

Detailed description:

Arms:
arm 1: Bevacizumab + FOLFOX arm 2: Cediranib + FOLFOX

Interventions: intervention 1: Cediranib intervention 2: Bevacizumab intervention 3: 5-fluorouracil ( in FOLFOX) intervention 4: Leucovorin (in FOLFOX) intervention 5: Oxaliplatin (in FOLFOX)
Intervention descriptions: intervention 1: oral tablet once daily intervention 2: intravenous infusion intervention 3: intravenous infusion intervention 4: intravenous infusion intervention 5: intravenous infusion

Protocol document: