Conditions: Raised Intraocular Pressure
Keywords: Raised intraocular pressure
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy of systemically administered AZD4017, compared with placebo, over a 28-day period in patients with raised intra-ocular pressure (IOP).

Detailed description:

Arms:
arm 1: Europe: 200 mg AZD4017 arm 2: Europe: placebo arm 3: USA: 800 mg AZD4017 arm 4: USA: placebo

Interventions: intervention 1: AZD4017 intervention 2: Placebo intervention 3: AZD4017 intervention 4: Placebo
Intervention descriptions: intervention 1: tablet, oral, one tablet once daily, 28 days intervention 2: matching placebo tablet, oral, one tablet once daily, 28 days intervention 3: tablet, oral 2 tablets twice daily, 28 days intervention 4: matching placebo tablets, oral, 2 tablets twice daily, 28 days

Protocol document: