Conditions: Alzheimer's Disease
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 24
Healthy volunteers: yes

Brief summary:
This study will test if two flortaucipir PET scans up to 4 weeks apart in healthy volunteers, MCI and AD subjects provide the same results.

Detailed description:

Arms:
arm 1: Healthy males or females 50 years or older with no evidence of cognitive impairment arm 2: Subjects 50 years or older with mild cognitive impairment (MCI) arm 3: Subjects 50 years or older with probable Alzheimer's Disease (AD)

Interventions: intervention 1: Flortaucipir F18 intervention 2: Brain PET scan
Intervention descriptions: intervention 1: IV injection, 370 MBq (10 mCi), two doses up to four weeks apart intervention 2: positron emission tomography (PET) scan of the brain at 80-100 and 110-130 minutes after injection

Protocol document: