Conditions: Pain
Keywords: Pain abdominoplasty PCA
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 200
Healthy volunteers: no

Brief summary:
The primary objective is to evaluate the analgesic efficacy of IV TRV130 compared with placebo in patients with acute postoperative pain following abdominoplasty.

Detailed description:
The primary objective is to evaluate the analgesic efficacy of intravenous (IV) TRV130 administered via patient controlled analgesia device (PCA) compared with placebo administered via PCA in patients with moderate to severe, acute postoperative pain following abdominoplasty.

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: TRV130 intervention 2: Morphine intervention 3: Placebo
Intervention descriptions: intervention 1: Rescue: Ibuprofen, oxycodone intervention 2: Rescue: Ibuprofen, oxycodone intervention 3: Rescue: Ibuprofen, oxycodone

Protocol document: