Conditions: Cystic Fibrosis Healthy
Keywords: exhaled breath condensate diffusion capacity of the lungs for carbon monoxide and nitric oxide albuterol peripheral oxygen saturation ion regulation
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 32
Healthy volunteers: yes

Brief summary:
Our aims were to determine if exhaled breath condensate (EBC) could detect differences in ion regulation between cystic fibrosis (CF) and healthy and measure the effect of the albuterol on EBC ions in these populations. We hypothesized EBC chloride and sodium would be lower in CF patients at baseline and that albuterol would decrease EBC sodium and increase EBC chloride.

Detailed description:

Arms:
arm 1: 2.5 mg diluted in 3mL normal saline nebulized using a Power Neb2 nebulizer arm 2: nebulized 3 ml normal saline using a Power Neb2 nebulizer

Interventions: intervention 1: Albuterol intervention 2: Placebo saline
Intervention descriptions: intervention 1: 2.5 mg diluted in 3mL normal saline nebulized using a Power Neb2 nebulizer intervention 2: nebulized 3mL normal saline) using a Power Neb2 nebulizer

Protocol document: