Conditions: Allergic Conjunctivitis
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 50
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effectiveness and safety of Olopatadine Hydrochloride (HCl) ophthalmic solution 0.1% versus Epinastine HCl ophthalmic solution, 0.05% in a population of healthy, adult Japanese patients (20 years of age or older) with a history of allergic conjunctivitis to Japanese Cedar Pollen. Patients will be randomly assigned to receive Olopatadine HCl ophthalmic solution, 0.1% in one eye and Epinastine HCl ophthalmic solution, 0.05% in the fellow eye, after which a conjunctival allergy challenge (CAC) with Japanese cedar pollen will be performed.

Detailed description:

Arms:
arm 1: Olopatadine HCl ophthalmic solution, 0.1%, 1 drop in the right or left eye as randomized arm 2: Epinastine HCl ophthalmic solution, 0.05%, 1 drop in the in the fellow eye

Interventions: intervention 1: Olopatadine HCl ophthalmic solution, 0.1% intervention 2: Epinastine HCl ophthalmic solution, 0.05%
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: