Conditions: Healthy
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 26
Healthy volunteers: yes

Brief summary:
To investigate the effect of the P-gp inducer rifampicin on the pharmacokinetic parameters of nintedanib

Detailed description:

Arms:
arm 1: multiple doses of Rifampicin + single dose of Nintedanib arm 2: single dose of Nintedanib

Interventions: intervention 1: Nintedanib intervention 2: Rifampicin intervention 3: Nintedanib
Intervention descriptions: intervention 1: single dose administration intervention 2: single dose once daily for 7 days intervention 3: single dose administration

Protocol document: