Conditions: Asthma
Keywords: Allergen Challenge Asthma Inhaled selective glucocorticoid receptor agonist (iSEGRA)
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 27
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy of AZD5423 in patients with mild asthma challenged with an inhaled allergen.

Detailed description:

Arms:
arm 1: AZD5423 75ug arm 2: AZD5423 300ug arm 3: Budesonide 200 microgram arm 4: Placebo

Interventions: intervention 1: AZD5423 intervention 2: Budesonide 200 microgram intervention 3: Placebo intervention 4: Placebo
Intervention descriptions: intervention 1: Suspension for nebulisation once daily 7 days intervention 2: Dry powder for inhalation twice daily 7 days intervention 3: Solution for nebulisation once daily 7 days intervention 4: Solution for nebulisation once daily 7 days

Protocol document: