Conditions: Healthy
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 51
Healthy volunteers: yes

Brief summary:
To investigate the effect of steady-state itraconazole on the pharmacokinetics of steady-state of faldaprevir and the effect of steady-state of faldaprevir on the single-dose pharmacokinetics of atorvastatin as well as the effect of steady-state of faldaprevir on the single-dose pharmacokinetics of rosuvastatin

Detailed description:

Arms:
arm 1: Interaction of Faldaprevir and Itraconazole arm 2: Interaction of Faldaprevir, Rosuvastatin and Atorvastatin

Interventions: intervention 1: Itraconazole intervention 2: Atorvastatin intervention 3: Faldaprevir intervention 4: Rosuvastatin intervention 5: Faldaprevir
Intervention descriptions: intervention 1: twice daily intervention 2: single dose intervention 3: once daily intervention 4: single dose intervention 5: once daily

Protocol document: