Conditions: Healthy
Keywords: HSV HIV Herpes volunteers drug-drug interaction
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 48
Healthy volunteers: yes

Brief summary:
ASP2151 is an experimental treatment for herpes. HIV infected people are susceptible to contracting other infections because of their compromised immune system. As HIV patients will be taking drugs to treat the virus this study aims to see if ASP2151 would interact with one of the drugs that is commonly prescribed to HIV patients (ritonavir).

Detailed description:

Arms:
arm 1: 400mg ASP2151 alone followed by 400mg ASP2151 + 600mg ritonavir arm 2: 1200mg ASP2151 alone followed by 1200mg ASP2151 + 600mg ritonavir

Interventions: intervention 1: ASP2151 intervention 2: ritonavir
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: