Conditions: Malaria
Keywords: Malaria Bio-availability
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 22
Healthy volunteers: yes

Brief summary:
A single dose study to investigate how different formulations of OZ439 co-administered with PQP tablest are processed by the body when taken without food

Detailed description:

Arms:
arm 1: 800mg OZ439 prototype formulation 1 and 960mg PQP single doses arm 2: 800mg OZ439 prototype formulation 2 and 960mg PQP single doses arm 3: 800mg OZ439 prototype formulation 3 and 960mg PQP single doses

Interventions: intervention 1: 800mg OZ439 prototype formulation 1 intervention 2: 800mg OZ439 prototype formulation 2 intervention 3: 800mg OZ439 prototype formulation 3 intervention 4: 960mg PQP
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: None intervention 4: None

Protocol document: