Conditions: Healthy Volunteer Study
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 27
Healthy volunteers: yes

Brief summary:
The study will evaluate the effect of activated charcoal on absorption of LY2140023. The study involves a single dose of 80 milligrams (mg) LY2140023 taken as 1 tablet by mouth 2 times during study (once with activated charcoal, once without activated charcoal). This study will last approximately 16 days, not including screening. Screening is required within 28 days prior to study entry.

Detailed description:

Arms:
arm 1: Single oral dose of 80 milligrams (mg) LY2140023 administered alone arm 2: Single oral dose of 80 mg LY2140023 followed 1 hour later by single oral dose of 75 grams (g) aqueous activated charcoal.

Interventions: intervention 1: LY2140023 intervention 2: Aqueous activated charcoal
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: