Conditions: Enamel Erosion
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 72
Healthy volunteers: yes

Brief summary:
The proposed study will evaluate the performance of fluoride delivered from a new dentifrice formulation without potassium nitrate. It will also evaluate the dose-response to fluoride by testing four dentifrices covering a range of sodium fluoride concentration.

Detailed description:

Arms:
arm 1: Low ppm fluoride as sodium fluoride in a silica base dentifrice arm 2: Medium ppm fluoride as sodium fluoride in a silica base dentifrice arm 3: High ppm fluoride as sodium fluoride in a silica base dentifrice arm 4: no added fluoride in a silica base dentifrice

Interventions: intervention 1: sodium fluoride intervention 2: no added fluoride in a silica base
Intervention descriptions: intervention 1: fluoride as sodium fluoride intervention 2: no added fluoride

Protocol document: