Conditions: Chronic Lymphocytic Leukemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 552
Healthy volunteers: no

Brief summary:
The purpose of this study is to provide treatment for patients who have chronic lymphocytic leukemia (CLL), and to compare the use of rituximab added to fludarabine+cyclophosphamide (FC) with FC alone, to determine if rituximab lengthens the time a patient remains free of leukemia symptoms.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Rituximab intervention 2: Fludarabine Phosphate intervention 3: Cyclophosphamide
Intervention descriptions: intervention 1: Intravenous repeating dose intervention 2: Intravenous repeating dose intervention 3: Intravenous repeating dose

Protocol document: