Conditions: Congestive Heart Failure Diabetes Mellitus
Keywords: Heart failure Hyperglycemia Hospital Diabetes Mellitus
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 74
Healthy volunteers: no

Brief summary:
Patients with heart failure often have high blood sugar (glucose).

Detailed description:
Patients with heart failure often have high blood sugar. High glucose contributes to severe hospital complications and even death. Studies suggest that heart failure patients who have high glucose or diabetes do not live as long as patients with normal glucose. In this study, we will determine whether normalizing blood sugars using intravenous insulin short-term will improve outcomes in patients hospitalized for congestive heart failure. We enrolled patients with severe heart failure and randomly assigned them into 2 groups. We used intravenous (given through the vein) insulin to lower blood sugar levels in group 1, and insulin injections in group 2. We determined whether intravenous insulin improved hospital length of stay, rates of readmission, inflammatory markers, and cardiovascular tests that predict mortality in patients with heart failure.

Arms:
arm 1: None arm 2: Basal bolus insulin (4 injections per day)

Interventions: intervention 1: Intravenous insulin intervention 2: Subcutaneous insulin
Intervention descriptions: intervention 1: Half of subjects will receive insulin through the intravenous route while the other half will receive 4 injections per day. intervention 2: Half of subjects will receive insulin through the intravenous route while the other half will receive 4 injections per day.

Protocol document: