Conditions: Type 2 Diabetes
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1484
Healthy volunteers: no

Brief summary:
The purpose of this clinical research study is to learn if BMS-512148 (Dapagliflozin) can help reduce the blood sugar levels in Asian patients with Type 2 Diabetes who are not well controlled on metformin alone. The safety of this treatment will also be studied.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Dapagliflozin intervention 2: Dapagliflozin intervention 3: Metformin intervention 4: Dapagliflozin Placebo intervention 5: Pioglitazone
Intervention descriptions: intervention 1: Tablets, Oral, 5 mg, Once daily, 24 weeks intervention 2: Tablets, Oral, 10 mg, Once daily, 24 weeks intervention 3: Tablets, Oral, 1500-3000 mg, Twice daily, 24 weeks intervention 4: Tablets, Oral, 0 mg, Once daily, 24 weeks intervention 5: Tablets, Oral, 15-45 mg (as needed for rescue based on protocol specific criteria), Up to 20 weeks

Protocol document: