Conditions: Essential Hypertension
Keywords: Hypertension Essential Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 837
Healthy volunteers: no

Brief summary:
The purpose of the study is to evaluate the safety and efficacy of a fixed-dose combination drug compared to two other drugs (monotherapies) in controlling hypertension.

Detailed description:

Arms:
arm 1: fixed-dose combination of perindopril arginine/amlodipine besylate(PERa/AMLb) arm 2: None arm 3: None

Interventions: intervention 1: XOMA 985 intervention 2: Amlodipine Besylate intervention 3: Perindopril Erbumine
Intervention descriptions: intervention 1: PERa/AMLb capsule taken once daily by mouth for six weeks intervention 2: AMLb capsule taken once daily by mouth for six weeks intervention 3: PERe capsule taken once daily by mouth for six weeks

Protocol document: