Conditions: Malaria
Keywords: P. falciparum malaria asymptomatic carriers bed-nets ITN-insecticide-treated net idiopathic trigeminal neuralgia RDT-Rapid diagnostic test
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 14075
Healthy volunteers: no

Brief summary:
This study assessed the impact of the systematic detection by Rapid Diagnostic Test (RDT) and treatment of asymptomatic carriers of malaria parasites (P. falciparum) with COA566 on a number of clinical malaria cases in children less than 5 years of age and the improvement of hemoglobin levels in the overall population.

Detailed description:

Arms:
arm 1: Participants received COA566 treatment for asymptomatic carriage of P. falciparum and for symptomatic malaria episodes. arm 2: Participants received COA566 treatment for symptomatic malaria episodes only.

Interventions: intervention 1: COA566
Intervention descriptions: intervention 1: COA566 tablets or dispersible tablets twice daily during 3 days; dosage according to body weight.

Protocol document: