Conditions: Non-Small Cell Lung Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 211
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare the efficacy and toxicity of pemetrexed and docetaxel administered on a 3-weekly schedule in the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who have had prior chemotherapy.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: pemetrexed intervention 2: docetaxel
Intervention descriptions: intervention 1: 500 mg/m2, intravenous (IV) every 21 days until disease progression, death or 12 months after enrollment intervention 2: 75 mg/m2, intravenous (IV), every 21 days until disease progression, death or 12 months after enrollment

Protocol document: