Conditions: Breast Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 120
Healthy volunteers: no

Brief summary:
To compare the anti-tumour effects as measured by changes in various biomarkers, of a combination of Faslodex and Arimidex with Faslodex alone and Arimidex alone in postmenopausal women patients with primary breast cancer who are awaiting curative-intent surgery.

Detailed description:

Arms:
arm 1: Anastrozole Monotherapy arm 2: Fulvestrant Monotherapy arm 3: Anastrozole + Fulvestrant

Interventions: intervention 1: Fulvestrant intervention 2: Anastrazole
Intervention descriptions: intervention 1: 500 mg intramuscular injection intervention 2: oral tablet

Protocol document: