Conditions: Type 2 Diabetes Mellitus
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 517
Healthy volunteers: no

Brief summary:
A study to evaluate the efficacy and safety of MK0431A in comparison to a commonly used medication in patients with type 2 diabetes

Detailed description:

Arms:
arm 1: Sitagliptin phosphate (+) metformin hydrochloride arm 2: pioglitazone

Interventions: intervention 1: sitagliptin phosphate (+) metformin hydrochloride intervention 2: Comparator: pioglitazone
Intervention descriptions: intervention 1: sitagliptin phosphate (+) metformin hydrochloride 50/500 mg tablet bid, titrating up to sitagliptin phosphate (+) metformin hydrochloride 50/1000 mg tablet for an \~32 wk treatment period intervention 2: pioglitazone 30 mg tablet qd, titrating up to 45 mg qd for an \~32-wk treatment period.

Protocol document: