Conditions: Pancreatic Neoplasm
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 130
Healthy volunteers: no

Brief summary:
The purpose of this research study is to determine the effects and toxicity of gemcitabine alone or gemcitabine plus enzastaurin in participants with pancreatic cancer.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: enzastaurin intervention 2: gemcitabine
Intervention descriptions: intervention 1: 1200 milligrams (mg) loading dose then 500 mg, orally, daily, six 28-day cycles intervention 2: 1000 milligrams/square meter (mg/m\^2), intravenously on Days 1, 8 and 15 per cycle, six 28-day cycles

Protocol document: