Conditions: Ulcerative Colitis
Keywords: Mesalamine Ulcerative Colitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1
Healthy volunteers: no

Brief summary:
To determine whether once a day administration of Mesalamine is at least as safe and efficacious and administration of multiple doses a day in preventing clinical relapse of ulcerative colitis in children and adolescence.

Detailed description:
Is taking total dose in mg/kg once a day, as safe as taking total dose divided in mg/kg spreadout during the day in preventing clinical relapse of ulcerative colitis in children and adolescence.

Arms:
arm 1: Asacol total dose in mg/kg given once a day arm 2: Asacol total dose split BID or TID

Interventions: intervention 1: Asacol
Intervention descriptions: intervention 1: Asacol is given once a day versus twice or three times a day

Protocol document: