Conditions: Urinary Incontinence (UI)
Keywords: Urge urinary incontinence (UUI) Drug/Behavior treatment
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 307
Healthy volunteers: yes

Brief summary:
The primary aim of this study is to test if the addition of behavioral treatment to drug therapy for the treatment of urge incontinence will increase the number of patients who can discontinue drug therapy and sustain a significant reduction of incontinence.

Detailed description:

Arms:
arm 1: Women randomly assigned to this condition receive 10 weeks of anti-cholinergic medication (tolterodine) and behavioral training. arm 2: Women assigned to this arm received 10 weeks of anti-cholinergic medication (tolterodine), only.

Interventions: intervention 1: Tolterodine intervention 2: Behavioral training
Intervention descriptions: intervention 1: 4mg/d for 10 weeks. Could be reduced to 2mg/d for managing side effects. intervention 2: Training in pelvic floor muscle control and exercises; behavioral strategies to diminish urgency, suppress bladder contractions and prevent incontinence; delayed voiding; and individualized fluid management.

Protocol document: