Conditions: Vascular Disease, Peripheral
Keywords: Restenosis Superficial Femoral Artery Prevention of restenosis Revascularization of the superficial Femoral Artery
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 6
Healthy volunteers: no

Brief summary:
The purpose of this study is to investigate the prevention of Restenosis following Revascularization of the superficial Femoral Artery (SFA)

Detailed description:

Arms:
arm 1: Following revascularization, participants did not receive any study drug treatment. arm 2: Participants received an initial intraarterial infusion (proximal to the lesion) of 45 mg/m\^2 nanoparticle paclitaxel immediately following revascularization, and a follow-up intravenous injection of 45 mg/m\^2 at 7 days. arm 3: Participants received an initial intraarterial infusion (during flow arrest) of 45 mg/m\^2 nanoparticle paclitaxel immediately following revascularization. arm 4: Participants received an initial intraarterial infusion (during flow arrest) of 45mg/m\^2 nanoparticle paclitaxel immediately following revascularization and a follow-up intravenous injection of 45 mg/m\^2 at 7 days.

Interventions: intervention 1: Nanoparticle Paclitaxel
Intervention descriptions: intervention 1: Nanoparticle albumin-bound paclitaxel, 45 mg/m\^2.

Protocol document: