Conditions: Allergy
Keywords: Sublingual immunotherapy Grass pollen tablet Allergic rhinoconjunctivitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 628
Healthy volunteers: no

Brief summary:
To evaluate the safety and efficacy of SLIT compared with placebo for reduction of symptoms and rescue medication usage

Detailed description:

Arms:
arm 1: 100 IR grass pollen allergen extract tablet arm 2: 300 IR grass pollen allergen extract tablet arm 3: 500 IR grass pollen allergen extract tablet arm 4: Placebo tablet

Interventions: intervention 1: 100 IR grass pollen allergen extract tablet intervention 2: 300 IR grass pollen allergen extract tablet intervention 3: 500 IR grass pollen allergen extract tablet intervention 4: Placebo tablet
Intervention descriptions: intervention 1: One sublingual tablet daily during 4 months before pollen season and during pollen season intervention 2: One sublingual tablet daily during 4 months before pollen season and during pollen season intervention 3: One sublingual tablet daily during 4 months before pollen season and during pollen season intervention 4: One sublingual tablet daily during 4 months before pollen season and during pollen season

Protocol document: