Conditions: Dermatitis, Chronic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 125
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine how clobetasol proprionate foam works against a placebo foam in the treatment of hand dermatitis.

Detailed description:
Topical corticosteroids have anti-inflammatory, immunosuppressive and antiproliferative properties. Clobetasol propionate foam 0.05% (Olux-E), a Class 1 corticosteroid, is formulated in an ethanol free petrolatum base that provides the benefits of a super-potent corticosteroid combined with moisturizing ingredients in the treatment of corticosteroid responsive dermatoses. The current study is designed to show efficacy and safety in the treatment of moderate to severe chronic hand dermatitis.

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: clobetasol propionate 0.05% intervention 2: Vehicle / Placebo
Intervention descriptions: intervention 1: 2 times a day, 14 total days study treatment intervention 2: 2 times a day, 14 total days of study treatment

Protocol document: