Conditions: Anesthesia
Keywords: anesthesia desflurane
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 216
Healthy volunteers: no

Brief summary:
The purposes of this study are to evaluate the efficacy and safety of desflurane (BLM-240) as an anesthetic agent and to demonstrate the non-inferiority of desflurane to sevoflurane in term of awakening/recovery from anesthesia.

Detailed description:
The study evaluates the efficacy and safety of the use of desflurane (BLM-240) (with and without nitrous oxide) in maintenance of general anesthesia in adult patients undergoing surgical procedures typically performed under general anesthesia in Japan (thoracic, abdominal, joints, back, and neck), where analgesics and muscle relaxants are concomitantly used. The study is also intended to demonstrate the non-inferiority of desflurane with nitrous oxide to sevoflurane with nitrous oxide in time to awakening/recovery.

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: desflurane intervention 2: desflurane/nitrous oxide intervention 3: sevoflurane/nitrous oxide
Intervention descriptions: intervention 1: volatile liquid for inhalation intervention 2: volatile liquid for inhalation with gas for inhalation intervention 3: volatile liquid for inhalation and gas for inhalation

Protocol document: