Conditions: Scarring Impaired Wound Healing
Keywords: wound healing scarring collagenase Santyl
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 28
Healthy volunteers: yes

Brief summary:
A study to compare the rate of complete wound closure and quality of resulting scar at 3, 6 and 9 months, between dermatome-induced skin wounds treated with Collagenase Santyl Ointment versus vehicle alone.

Detailed description:

Arms:
arm 1: Dermatome-induced skin wounds treated with drug active (collagenase). arm 2: Dermatome-induced skin wounds treated with Vehicle alone.

Interventions: intervention 1: Collagenase Santyl intervention 2: Collagenase Santyl Vehicle
Intervention descriptions: intervention 1: Dermatome-induced skin wounds treated with drug active.

Each subject serves as his own control receiving both treatments in parallel. intervention 2: Dermatome-induced skin wounds treated with Vehicle alone. Each subject serves as his own control receiving both treatments in parallel.

Protocol document: