Conditions: Peritonsillar Abscess
Keywords: Peritonsillar Abscess Quinsy Penicillin Metronidazole Recurrence
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 200
Healthy volunteers: no

Brief summary:
Treatment of peritonsillar abscess varies. To study whether broad spectrum antibiotics are required in addition to abscess drainage, a prospective, double blind, placebo-controlled, randomized study on 200 adult patients with peritonsillar abscess is performed. 100 patients are given penicillin and metronidazole and 100 patients get penicillin and placebo. Recovery and recurrence are analyzed.

Detailed description:

Arms:
arm 1: After incision and drainage 100 randomized patients receive penicillin and metronidazole as treatment of peritonsillar abscess arm 2: After incision and drainage 100 randomized patients receive penicillin and placebo as treatment of peritonsillar abscess

Interventions: intervention 1: penicillin and metronidazole in peritonsillar abscess
Intervention descriptions: intervention 1: Peroral Penicillin: 1000 000 IU 3 times a day for 10 days Peroral metronidazole: 500 mg 3 times a day for 7 days

Protocol document: