Conditions: Hypercholesterolemia
Keywords: HMG-CoA LDL-C CHD
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 934
Healthy volunteers: no

Brief summary:
This trial is to compare the efficacy, safety and tolerability of Rosuvastatin with Atorvastatin by assessing the change of LDL-C in patients with hypercholesterolemia and history of coronary heart disease (CHD) or risk equivalent, or a 10 year CHD risk of no less than 10%, following 6-week treatment and a possible 6 week extension treatment.

Detailed description:

Arms:
arm 1: Rosuvastatin 5mg qd arm 2: Rosuvastatin 10mg qd arm 3: Atorvastatin 10mg qd

Interventions: intervention 1: Rosuvastatin intervention 2: Atorvastatin
Intervention descriptions: intervention 1: Capsule/Tablet, oral, qd, 6 or 12 weeks intervention 2: Capsule/Tablet, 10mg, oral, qd, 6 weeks

Protocol document: