Conditions: Anesthesia
Keywords: Pediatric patients undergoing surgery
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 61
Healthy volunteers: no

Brief summary:
This study will determine the pharmacokinetics of intravenous (IV) methadone in children undergoing surgery.

Detailed description:

Arms:
arm 1: Methadone 0.1mg/kg arm 2: Methadone 0.2mg/kg arm 3: Methadone 0.3mg/kg arm 4: No methadone

Interventions: intervention 1: Methadone 0.1mg/kg intervention 2: Methadone 0.2mg/kg intervention 3: Methadone 0.3mg/kg intervention 4: Control
Intervention descriptions: intervention 1: Subjects will receive methadone as their intraoperative opioid. intervention 2: Subjects will receive methadone as their intraoperative opioid. intervention 3: Subjects will receive methadone as their intraoperative opioid. intervention 4: Subjects will not receive methadone as their intraoperative opioid.

Protocol document: