Conditions: Plaque Psoriasis
Keywords: Plaque psoriasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 36
Healthy volunteers: no

Brief summary:
This is a two-arm, parallel group, double-blind, placebo-controlled proof-of-concept study comparing 3 mg/kg of AIN457 to placebo. Subjects with a diagnosis of moderate to severe stable plaque psoriasis will be randomized to receive either AIN457 or placebo. AIN457 or placebo will be administered by single infusion at baseline and subjects will be observed for up to 26 weeks following the infusion.

Detailed description:

Arms:
arm 1: AIN457A 3mg/kg was administered intravenously as a single dose. arm 2: Placebo was administered intravenously as a single dose.

Interventions: intervention 1: AIN457 intervention 2: Placebo
Intervention descriptions: intervention 1: single infusion of 3 mg/kg intervention 2: single infusion of placebo

Protocol document: