Conditions: Dental Plaque
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 6
Healthy volunteers: yes

Brief summary:
To determine the effect of an amino acid on bacterial glycolytic acid formation in human interdental plaque.

Detailed description:

Arms:
arm 1: fluoride/triclosan/copolymer toothpaste arm 2: fluoride only toothpaste arm 3: fluoride/triclosan/amino acid toothpaste

Interventions: intervention 1: Triclosan, Fluoride intervention 2: fluoride intervention 3: Fluoride, triclosan, amino acid
Intervention descriptions: intervention 1: Rinse 3 times daily with assigned toothpaste slurry intervention 2: Rinse 3 times daily with assigned toothpaste slurry intervention 3: Rinse 3 times daily with assigned toothpaste slurry

Protocol document: