Conditions: Pain
Keywords: Pain following third molar extraction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 335
Healthy volunteers: no

Brief summary:
This study will compare the pain relieving effect of a single-dose of a novel ibuprofen formulation to placebo and two formulations of standard ibuprofen in the treatment of post-surgical dental pain following "wisdom" tooth (third molar) removal.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: Novel Ibuprofen intervention 2: Standard Ibuprofen intervention 3: Standard Ibuprofen intervention 4: Placebo
Intervention descriptions: intervention 1: Single-dose of novel ibuprofen (equal to 400 mg ibuprofen) intervention 2: Single-dose of standard ibuprofen (400mg) intervention 3: Single-dose of standard ibuprofen (400mg) intervention 4: Single-dose of placebo

Protocol document: