Conditions: Parkinson's Disease
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 328
Healthy volunteers: no

Brief summary:
This is a multicentre, open-label extension study to evaluate the long-term safety, tolerability, and efficacy of Perampanel (E2007) as an adjunctive therapy in levodopa treated PD subjects with motor fluctuations. All subjects who have completed E2007-E044-213 or E2007-G000-309 will be candidates for entering this extension trial, provided that they meet the inclusion/exclusion criteria and have completed the core study, up to and including the final efficacy visit.

Detailed description:

Arms:
arm 1: E2007 2 mg (one 2 mg tablet taken daily in the evening), or 4 mg (two 2 mg tablets daily in the evening).

Interventions: intervention 1: Perampanel
Intervention descriptions: intervention 1: None

Protocol document: