Conditions: Asthma
Keywords: Asthma
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 61
Healthy volunteers: no

Brief summary:
Subjects aged 1-8 years who have been discharged from the emergency department/outpatient care facility with a diagnosis of asthma/bronchospasm/wheezing after usual standard care will be enrolled into this open-label, randomized, parallel-group study to compare the efficacy of nebulized budesonide and oral corticosteroids in preventing asthma exacerbation relapse rates during the 21-day follow-up period.

Detailed description:
Secondary outcomes include urinary cortisol-creatinine rations, symptom severity scores and peak flow rates.

Arms:
arm 1: Subject is treated with nebulized budesonide 0.5 BID for 3 weeks arm 2: Subject is treated with usual care as provided by the doctor. Usual care normally consists of treatment with albuterol with or without an oral steroid.

Interventions: intervention 1: Nebulized Budesonide intervention 2: Usual care (albuterol with or without oral steroid)
Intervention descriptions: intervention 1: Subject is treated with nebulized budesonide 0.5 BID for 3 weeks intervention 2: Subject is treated with usual care as prescribed by the doctor (normally albuterol with or without oral steroid)

Protocol document: