Conditions: Infectious Diseases
Keywords: Pediatrics Safety Musculoskeletal System Neurologic Manifestations Joint Diseases Joint Deformities, Acquired
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1029
Healthy volunteers: no

Brief summary:
Objective and subjective musculoskeletal evaluations will be performed to determine differences in the ciprofloxacin versus non-quinolone treated pediatric patients so that we can tell what the natural occurrence of such musculoskeletal conditions is in the general pediatric population.

Detailed description:
This study is classified as "interventional" due to study-specific medical examinations and interventions. Regarding the study drug intake, routine administration is observed only, there is no intervention in study drug administration.

Arms:
arm 1: Subjects receiving Ciprofloxacin (group followed-up for 5 years) arm 2: Subjects receiving non-quinolone antibiotic (group followed-up for 2 years)

Interventions: intervention 1: Ciprofloxacin intervention 2: Non-quinolone antibiotic
Intervention descriptions: intervention 1: Either as oral suspension, oral tablets or sequential intravenous (IV) - oral therapy or purely IV therapy according to label intervention 2: Common used dose and route

Protocol document: