Conditions: Coronary Artery Disease
Keywords: Platelet function
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 72
Healthy volunteers: no

Brief summary:
The 5-milligram (mg) dose of prasugrel in low body weight (LBW) patients with coronary artery disease produces a pharmacodynamic response within the same therapeutic range as 10-mg dose in higher body weight (HBW) patients.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: prasugrel intervention 2: clopidogrel
Intervention descriptions: intervention 1: Administered orally, daily for 12 days intervention 2: Administered orally, daily for 12 days

Protocol document: