Conditions: Staphylococcal Infection
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 122
Healthy volunteers: no

Brief summary:
The study investigates the efficacy and safety of MK-3009 in participants with skin infections, septicemia and right-sided infective endocarditis (RIE) caused by methicillin-resistant Staphylococcus aureus (MRSA).

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Daptomycin 4 mg/kg intervention 2: Comparator: vancomycin intervention 3: Daptomycin 6 mg/kg
Intervention descriptions: intervention 1: MK3009 (daptomycin) once daily by intravenous (IV) drip, 4 mg/kg for 7-14 days for skin and soft tissue infections (SSTI) intervention 2: vancomycin 1g, twice daily (b.i.d.) by IV drip, for 7-14 days intervention 3: MK-3009 (daptomycin) once daily by intravenous drip, 6 mg/kg for 14-42 days for septicemia or right-sided infective endocarditis

Protocol document: