Conditions: Anesthesia, General
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 115
Healthy volunteers: no

Brief summary:
The purpose of the trial is to demonstrate a faster recovery from neuromuscular block induced by 1.2 mg/kg rocuronium after reversal at 3 minutes by 16.0 mg/kg of sugammadex compared with recovery after a neuromuscular block induced by 1.0 mg/kg succinylcholine.

Detailed description:

Arms:
arm 1: Participants were to receive a single bolus dose of 1.2 mg/kg rocuronium. Three minutes after the start of the rocuronium administration, they were to receive a single bolus dose of 16.0 mg/kg sugammadex. arm 2: Participants were to receive a single bolus dose of 1.0 mg/kg succinylcholine and allowed to recovery spontaneously from neuromuscular blockade.

Interventions: intervention 1: Sugammadex intervention 2: Succinylcholine intervention 3: Rocuronium
Intervention descriptions: intervention 1: Single bolus intravenous (IV) dose of 16.0 mg/kg sugammadex intervention 2: Single bolus IV dose of 1.0 mg/kg succinylcholine intervention 3: Single bolus IV dose of 1.2 mg/kg rocuronium

Protocol document: