Conditions: Type 2 Diabetes Mellitus
Keywords: exenatide diabetes Amylin Lilly glimepiride
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1029
Healthy volunteers: no

Brief summary:
This study assesses the effects of twice-daily subcutaneous injection exenatide versus treatment with sulfonylurea (glimepiride) on long-term glycemic control and beta-cell function.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: exenatide intervention 2: glimepiride
Intervention descriptions: intervention 1: subcutaneous injection (5mcg or 10mcg), twice a day intervention 2: oral tablet (titrated to maximally tolerated dose), once daily

Protocol document: