Conditions: Psoriasis Vulgaris
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 782
Healthy volunteers: no

Brief summary:
There are few therapies suitable for the treatment of psoriasis on the face and skin folds. As these areas are sensitive, irritation and other adverse reactions are more common than elsewhere on the body. The purpose of the study is to compare the efficacy and safety of once daily treatment for up to 8 weeks of an ointment containing calcipotriol 25 mcg/g plus hydrocortisone 10 mg/g with tacalcitol 4 mcg/g ointment and the ointment vehicle alone in patients with psoriasis vulgaris on the face and on the intertriginous ares

Detailed description:

Arms:
arm 1: Calcipotriol plus Hydrocortisone ointment once daily for up to 8 weeks arm 2: Tacalcitol once daily for up to 8 weeks arm 3: Calcipotriol plus Hydrocortisone ointment vehicle once daily for up to 8 weeks

Interventions: intervention 1: Calcipotriol plus hydrocortisone ointment vehicle intervention 2: Tacalcitol Ointment intervention 3: Calcipotriol plus hydrocortisone ointment
Intervention descriptions: intervention 1: Once daily application for up to 8 weeks intervention 2: Once daily application for up to 8 weeks intervention 3: Once daily application for up to 8 weeks

Protocol document: