Conditions: Hormone Replacement Therapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 249
Healthy volunteers: no

Brief summary:
Multicenter, double-blind, controlled, parallel group, randomized study to compare the clinical benefit of Estradiol acetate tablets, estradiol tablets and conjugated equine estrogen tablets, each administered orally, once daily, to postmenopausal women.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Estradiol acetate intervention 2: Estradiol intervention 3: Conjugated equine estrogens
Intervention descriptions: intervention 1: Tablet containing 0.9 mg E3A, daily oral administration. intervention 2: Tablet containing 1 mg estradiol, daily oral administration. intervention 3: Tablet containing 0.625 mg CEE, daily oral administration.

Protocol document: