Conditions: Alzheimer's Disease
Keywords: Alzheimer's disease antibody amyloid
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 198
Healthy volunteers: no

Brief summary:
Purpose of the study is to determine whether multiple dose administration of PF-04360365 is safe and well tolerated in patient with mild to moderate Alzheimer's disease.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None arm 6: None

Interventions: intervention 1: PF-04360365 0.1 mg/kg intervention 2: PF-04360365 0.5 mg/kg intervention 3: PF-04360365 1 mg/kg intervention 4: Placebo intervention 5: PF-04360365 3 mg/kg intervention 6: PF-04360365 8.5 mg/kg
Intervention descriptions: intervention 1: 0.1 mg/kg every 60 days (10 doses total) intervention 2: 0.5 mg/kg every 60 days (10 doses total) intervention 3: 1 mg/kg every 60 days (10 doses total) intervention 4: Placebo every 60 days (10 doses total) intervention 5: 3 mg/kg every 60 days (10 doses total) intervention 6: 8.5 mg/kg every 60 days (10 doses total)

Protocol document: