Conditions: Hot Flashes
Keywords: prostate cancer soy androgen deprivation quality of life isoflavones
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 39
Healthy volunteers: yes

Brief summary:
This study will look at the effects of a soy supplement called Revival on memory, quality of life, and hot flashes in men with prostate cancer who are being treated with testosterone suppression therapy. Hypothesis: Treating men who have prostate CA with daily Revival will result in at least a 50% reduction in hot flashes compared to placebo.

Detailed description:
This research study will look at the effects of a soy supplement called Revival on memory, quality of life, and hot flashes in men with prostate cancer who are undergoing (ADT) androgen deprivation therapy. Participants will be given either placebo or Revival. Participants will be asked to take their supplement once/day for 14 weeks.Blood will be drawn to check on liver, kidney, thyroid, cholesterol,and prostate health. Urine will be collected to check on bone markers. Patients will be asked to complete questionnaires to test memory, attention span, and vocabulary.Possible benefits may include increase in memory, decrease in hot flashes, and a general increase in quality of life.

Arms:
arm 1: Isoflavone arm 2: None

Interventions: intervention 1: Isoflavone intervention 2: Placebos
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: