Conditions: Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: no

Brief summary:
Evaluate pleiotropic effects of simvastatin in hypertensive patients.

Detailed description:

Arms:
arm 1: Participants who were administered Valsartan 80 mg plus paravastin 40 mg by mouth daily for one year. (Group A) arm 2: Participants who were administered Valsartan 80 mg plus simvastatin 40 mg by mouth daily for one year. (Group B) arm 3: Participants who were administered Valsartan 80 mg plus simvastatin 40 mg / ezetimibe 10 mg by mouth daily for one year. (Group C) arm 4: Participants who were administered Valsartan 80 mg by mouth daily for one year. (Group D)

Interventions: intervention 1: valsartan intervention 2: pravastatin intervention 3: simvastatin intervention 4: ezetimibe (+) simvastatin
Intervention descriptions: intervention 1: 80 mg valsartan. Duration: 12 months. Tablets intervention 2: 40 mg pravastatin. Duration: 12 months. Tablets intervention 3: 40 mg simvastatin. Duration: 12 months. Tablets intervention 4: ezetimibe (+) simvastatin 10/40 mg. Duration: 12 months. Tablets

Protocol document: