Conditions: Epithelium, Corneal
Keywords: Removal of corneal epithelium followed by excimer laser treatment during prk
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 40
Healthy volunteers: yes

Brief summary:
The purpose of this study is a prospective,double-blinded, randomized trial to compare the rate of healing following PRK after the use of two commercially available 4th generation fluoroquinolones, moxifloxacin and gatifloxacin.

Detailed description:

Arms:
arm 1: Moxifloxacin eye drops; 1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery arm 2: Gatifloxacin eyedrops; 1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery

Interventions: intervention 1: Moxifloxacin intervention 2: Gatifloxacin
Intervention descriptions: intervention 1: 1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery intervention 2: 1 drop 4 times daily for 1 week or until complete re-epithelization (usually 3-4 days) after surgery

Protocol document: