Conditions: Healthy
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 20
Healthy volunteers: yes

Brief summary:
The objective of the study is to investigate the relative bioavailability of digoxin after concomitant multiple oral administration of BI 10773 and a single dose of digoxin in comparison to digoxin given alone to healthy male and female subjects.

Detailed description:

Arms:
arm 1: Tablet, oral administration with 240 mL water arm 2: Tablets, oral administration with 240 mL water

Interventions: intervention 1: Digoxin plus BI 10773 intervention 2: Digoxin
Intervention descriptions: intervention 1: Digoxin 0.5 mg as single dose, BI 10773 medium dose once daily intervention 2: Digoxin 0.5 mg as single dose

Protocol document: