Conditions: Sickle Cell Disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 47
Healthy volunteers: no

Brief summary:
To determine the pharmacokinetics of methadone in children and adults with SCD who are experiencing a painful episode.

Detailed description:

Arms:
arm 1: Methadone comparison to standard of care for pain management arm 2: Morphine standard of Care pain management arm 3: Methadone comparison to standard of care for pain management arm 4: Morphine standard of Care pain management

Interventions: intervention 1: Morphine intervention 2: Methadone
Intervention descriptions: intervention 1: Standard of care for pain management of acute episode of pain intervention 2: Compare to standard of care for pain management of acute episode of pain

Protocol document: