Conditions: Prostate Cancer Hormonal Cycling
Keywords: Prostate Cancer Hormones 01-085 ANTIFUNGAL ANTIBIOTICS ESTROGENS LUPRON TESTOSTERONE ZOLADEX
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 36
Healthy volunteers: no

Brief summary:
Objective: To determine the response to rapid hormonal cycling in patients with non-castrate prostate cancer.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: GnRH intervention 2: Ketoconazole intervention 3: Bicalutamide intervention 4: Testosterone transdermal gel intervention 5: Estrogen transdermal patch
Intervention descriptions: intervention 1: leuprolide and goserelin are gonadotropin-releasing hormone analogues intervention 2: An imidazole antifungal agent. reduces adrenal and testicular androgen production in men intervention 3: A pure nonsteroidal antiandrogen intervention 4: an androgenic anabolic steroid intervention 5: Estradiol is the primary and most potent estrogen

Protocol document: