Conditions: Exercise Induced Asthma
Keywords: Exercise induced asthma Mild intermittent asthma Exercise induced bronchoconstriction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 66
Healthy volunteers: no

Brief summary:
1. The primary objective of this study is:

   * To evaluate the magnitude of the protective effect of the combination of budesonide and formoterol on an as-needed basis compared to the use of terbutaline as-needed on exercise induced bronchoconstriction in adults and adolescents with mild intermittent asthma
2. The secondary objectives of this study are:

   * To evaluate the magnitude of the protective effect of the combination of budesonide and formoterol as-needed compared to regular once daily use of budesonide plus terbutaline as-needed on exercise induced bronchoconstriction in adults and adolescents with mild intermittent asthma
   * To evaluate safety of budesonide/formoterol as-needed, terbutaline as-needed and regular use of budesonide + terbutaline as-needed as terms of adverse event

Detailed description:

Arms:
arm 1: budesonide 400yg + terbutaline 0.4 mg as-needed arm 2: placebo + terbutaline 0.4 mg as-needed arm 3: placebo + budesonide/formoterol 160/4.5 yg as-needed

Interventions: intervention 1: budesonide intervention 2: terbutaline intervention 3: budesonide/formoterol
Intervention descriptions: intervention 1: 400 yg x 1 intervention 2: 0.4 mg as-needed intervention 3: 160/4.5 yg as-needed

Protocol document: