Conditions: Parkinson's Disease
Keywords: Parkinson's disease time to "on" delayed on
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 20
Healthy volunteers: no

Brief summary:
To find out if a single dose of Parcopa®, a form of levodopa that dissolves in your mouth, works faster than regular oral levodopa which is swallowed, in fluctuating PD patients.

Detailed description:
This is a study to compare orally dissolving levodopa (Parcopa) to the conventional immediate release oral levodopa. This is a single-dose, double-blind, placebo controlled crossover trial in participants with Parkinson disease.

Arms:
arm 1: Parcopa at equivalent dosage to subjects current stable dose arm 2: Carbidopa-levodopa (Sinemet)at subjects current stable dose

Interventions: intervention 1: Parcopa intervention 2: carbidopa-levodopa (Sinemet)
Intervention descriptions: intervention 1: at subjects current stable dose of comparator intervention 2: at subjects current stable dose

Protocol document: