Conditions: Pulmonary Disease, Chronic Obstructive
Allocation:  | Intervention model: CROSSOVER
Enrollment: 344
Healthy volunteers: no

Brief summary:
The primary objective of this study is to demonstrate that treatment with a free combination of tiotropium and salmeterol provides superior improvement in static lung volumes and exercise tolerance compared to a fixed combination of fluticasone and salmeterol in patients with COPD.

The secondary objective includes assessment of safety.

Detailed description:

Arms:

Interventions: intervention 1: Tiotropium plus Salmeterol intervention 2: Fluticasone/Salmeterol
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: