Conditions: Advanced Breast Cancer
Keywords: Zactima
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 64
Healthy volunteers: no

Brief summary:
To assess the efficacy of ZD6474 in combination with docetaxel in the treatment of ABC using the progression event count methodology

Detailed description:

Arms:
arm 1: Docetaxel + placebo vandetanib arm 2: Vandetanib + Docetaxel

Interventions: intervention 1: Vandetanib (ZD6474) intervention 2: Docetaxel
Intervention descriptions: intervention 1: once daily oral dose intervention 2: intravenous infusion

Protocol document: