Conditions: Chronic Kidney Disease (CKD) Stage 5 Hypertrophy, Left Ventricular
Keywords: Zemplar, paricalcitol, PRIMO II
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: no

Brief summary:
To evaluate the effects of paricalcitol injection on cardiac structure and function over 48 weeks in subjects with Stage 5 Chronic Kidney Disease (CKD) receiving hemodialysis who have left ventricular hypertrophy (LVH).

Detailed description:

Arms:
arm 1: Paricalcitol Injection 4 mcg/mL given intravenously 3 times per week during dialysis arm 2: Placebo Injection 4 mcg/mL given intravenously three times a week during dialysis

Interventions: intervention 1: paricalcitol injection 4 mcg/mL intervention 2: Placebo Injection 4 mcg/mL
Intervention descriptions: intervention 1: Paricalcitol Injection 4 mcg/mL intravenously three times a week during dialysis intervention 2: Placebo Injection 4 mcg/mL given intravenously three times a week during dialysis

Protocol document: