Conditions: Osteoarthritis
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 6
Healthy volunteers: no

Brief summary:
The Purpose of this trial is to evaluate the use of a cross-over trial design in an osteoarthritis population. We will determine the inter- and intra-subject variability in osteoarthritis (OA) endpoints and evaluate if efficacy can be detected by measuring OA endpoints following treatment with 2 different types of analgesics in a crossover study of this design.

Detailed description:
Methodology study to evaluate the use of a cross over design and gait analysis. The study was terminated by mutual consent with the study site at a meeting on the 1 April 2009, because of slow recruitment due to a high screen fail rate. The study was not stopped for safety reasons.

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: celecoxib intervention 2: Oxycodone intervention 3: placebo
Intervention descriptions: intervention 1: oral, 100 mg bid intervention 2: oral, 20 mg bid intervention 3: oral bid

Protocol document: