Conditions: Injuries Shock, Traumatic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 81
Healthy volunteers: no

Brief summary:
Hypothesis: We hypothesize that resuscitation regimens which minimize the total volume of resuscitation fluid, while restoring organ perfusion, will lead to lower morbidity and mortality in critically ill patients following trauma.

Detailed description:

Arms:
arm 1: Vasopressin arm 2: bolus of NS (normal saline) followed by continuous infusion of NS, no vasopressin added

Interventions: intervention 1: normal saline control intervention 2: vasopressin
Intervention descriptions: intervention 1: no vasopressin added to bolus or 5 hour continuous infusion intervention 2: vasopressin bolus 4 units followed by continuous infusion 2.4units/hr for 5 hours

Protocol document: