Conditions: Glaucoma
Keywords: Glaucoma
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 111
Healthy volunteers: no

Brief summary:
To evaluate the Intraocular Pressure (IOP) lowering efficacy and safety of Travoprost 0.004% compared to Timolol 0.5% in patients with open-angle glaucoma (OAG) or ocular hypertension (OH). The study structure is a parallel design. The patients will receive treatment for 12 weeks.

Detailed description:
To evaluate the IOP lowering efficacy and safety fo Travoprost 0.004% compared to Timolol 0.5% in patients with open-angle glaucoma (OAG) or ocular hypertension (OH). The study structure is a parallel design. The patients will receive treatment for 12 weeks.

Arms:
arm 1: Travoprost 0.004% arm 2: Timolol 0.5%

Interventions: intervention 1: Travoprost 0.004% Ophthalmic Solution (Travatan) intervention 2: Timolol 0.5% Ophthalmic Solution (Timoptic)
Intervention descriptions: intervention 1: Travoprost at 9 AM + Placebo \& 9 PM intervention 2: Timolol in each eye, twice daily at 9 AM \& 9 PM

Protocol document: