Conditions: Hypogonadism
Keywords: Hypogonadism Testosterone Hormone replacement therapy
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 40
Healthy volunteers: no

Brief summary:
The study will evaluate the pharmacokinetics of testosterone transdermal systems at steady-state in hypogonadal men.

Detailed description:
Subjects will receive testosterone for 4 weeks. Based on a single morning testosterone measurement performed at the end of Week 1, the dosage can be titrated up or down to the next dose level to maintain testosterone levels in the normal range. At the end of 4 weeks of treatment, a pharmacokinetic profile for total testosterone and metabolites will be obtained.

Arms:
arm 1: Testosterone

Interventions: intervention 1: Testerone Transdermal System
Intervention descriptions: intervention 1: Transdermal testosterone applied daily for 4 weeks

Protocol document: