Conditions: Total Knee Replacement
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 114
Healthy volunteers: no

Brief summary:
The investigators hypothesize that Arixtra patients will be less likely to experience wound infection than patients who have received low-molecular weight heparin, coumadin or aspirin with mechanical compression.

Detailed description:

Arms:
arm 1: Effect of Arixtra on would drainage and length of stay for the patients with hip and knee replacement

Interventions: intervention 1: Fondaparinux Sodium (Arixtra)
Intervention descriptions: intervention 1: 2.5 mg once per day to begin 6-8 hours after surgery and continued for 10 days.

Protocol document: