Conditions: Pancreatic Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 20
Healthy volunteers: no

Brief summary:
The purpose of this study is to obtain preliminary safety and efficacy data after endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) in patients with locally advanced or unresectable pancreatic adenocarcinoma.

Hypotheses:

1. Increased amounts of alcohol used in EUS-CPN is safe and more efficacious in improving pain relief in patients with locally advanced or unresectable pancreatic adenocarcinoma.
2. Effective pain relief obtained from EUS-CPN will be related to better quality of life (QOL)

Detailed description:

Arms:
arm 1: subject randomized to 10ml of dehydrated alcohol arm 2: subject randomized to 20ml of dehydrated alcohol

Interventions: intervention 1: dehydrated alcohol
Intervention descriptions: intervention 1: subject randomized to 10ml or 20ml of dehydrated alcohol one time during the EUS-CPN procedure

Protocol document: