Conditions: Ovarian Cancer Neoplasms, Ovarian
Keywords: HYCAMTIN ovarian cancer recurrent relapsed carboplatin topotecan potentially platinum-sensitive
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 77
Healthy volunteers: no

Brief summary:
This study was designed to find the most effective and safest doses of both HYCAMTIN and CARBOPLATIN that can be given for the treatment of ovarian cancer. This study may allow researchers to determine the effectiveness of combining HYCAMTIN and CARBOPLATIN.

Detailed description:

Arms:
arm 1: HYCAMTIN at a dose of 2.0 - 2.5mg/m2 on Days 1 and 8 every 21 days followed by carboplatin at AUC 5 on Day 1, every 21 days

Interventions: intervention 1: topotecan intervention 2: CARBOPLATIN
Intervention descriptions: intervention 1: HYCAMTIN at a dose of 2.0 mg/m2 on Days 1 and 8 every 21 days followed by carboplatin at AUC 5 on Day 1 intervention 2: HYCAMTIN at a dose of 2.0 mg/m2 on Days 1 and 8 every 21 days followed by carboplatin at AUC 5 on Day 1

Protocol document: