Conditions: Inflammatory Bowel Disease
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine the effect of rosiglitazone on the genes of the colon

Detailed description:
The primary aim of the study is to examine the effect of rosiglitazone (Avandia) on gene regulation in colonic epithelium in the absence of pathologic acute and chronic intestinal inflammation. The secondary aims are to determine the effect of rosiglitazone (Avandia) therapy on T cell activation and cytokine expression in the absence of pathologic acute and chronic intestinal inflammation.

Arms:
arm 1: Rosiglitazone; 8mg tablet once a day for 14 days

Interventions: intervention 1: Rosiglitazone
Intervention descriptions: intervention 1: 8mg tablet once a day for 14 days

Protocol document: