Conditions: Diabetes Mellitus, Type 2 End-Stage Kidney Disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 129
Healthy volunteers: no

Brief summary:
The purpose of the study is to compare sitagliptin and glipizide in lowering blood sugar in participants with type-2 diabetes mellitus (T2DM) and end-stage renal disease on dialysis who do not have adequate glycemic control.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Sitagliptin intervention 2: Glipizide
Intervention descriptions: intervention 1: 25 mg (one 25-mg tablet) once daily intervention 2: 2.5 mg (1/2 of a 5-mg tablet) once daily, up to 10 mg twice daily (four 5-mg tablets), for a maximum of 20 mg

Protocol document: