Conditions: Cold Sore
Keywords: cold sore
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 126
Healthy volunteers: no

Brief summary:
Comparison of the efficacy of penciclovir 10 mg/g (1%) cream with that of vehicle at 72 hours in preventing the appearance of classical lesions following prodromal symptoms (tingling or burning sensation) based on thermographic assessment among recurrent cold sore sufferers.

Detailed description:

Arms:
arm 1: Penciclovir arm 2: Placebo

Interventions: intervention 1: Penciclovir intervention 2: Placebo
Intervention descriptions: intervention 1: Penciclovir every 2 hours during waking hours for 96 hours intervention 2: Placebo every 2 hous during waking hours for 96 hours

Protocol document: