Conditions: Caries
Keywords: remineralization enamel in situ fluoride caries
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 65
Healthy volunteers: yes

Brief summary:
This study is to evaluate the effect of fluoride dentrifrices on enamel with artificial caries lesions in an in situ model

Detailed description:

Arms:
arm 1: Placebo arm 2: Sodium fluoride toothpaste arm 3: Amine Fluoride arm 4: Dose response arm 5: Sodium monofluorophosphate/sodium fluoride Toothpaste arm 6: None

Interventions: intervention 1: Sodium Fluoride Toothpaste intervention 2: Amine Fluoride Toothpaste intervention 3: Sodium monofluorophosphate/Sodium Fluoride Toothpaste intervention 4: Placebo intervention 5: 675 ppmf toothpaste
Intervention descriptions: intervention 1: Test product intervention 2: Test product intervention 3: test product intervention 4: placebo and washout treatment intervention 5: dose response

Protocol document: