Conditions: Erythematotelangiectatic Rosacea
Keywords: Erythematotelangiectatic Rosacea
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 122
Healthy volunteers: no

Brief summary:
This is a randomized, double-blind, parallel-group, vehicle-controlled, dose-finding study to investigate the pharmacodynamics and the safety of three dosages of CD07805/47 topical gel (0.07%, 0.18%, and 0.50%), after a single application in subjects with a clinical diagnosis of stable moderate to severe erythematotelangiectatic rosacea. Subjects will be randomized in a 1:1:1:1 ratio to receive either one of three CD07805/47 topical gel concentrations (0.07%, 0.18%, or 0.50%) or Vehicle Gel. All subjects will be treated with a single application (once daily dosing for one day) of study medication.

Detailed description:

Arms:
arm 1: 0.5% Topical Gel arm 2: 0.18% Topical Gel arm 3: 0.07% Topical Gel arm 4: Vehicle Topical Gel

Interventions: intervention 1: CD07805/47 intervention 2: CD07805/47 intervention 3: CD07805/47 intervention 4: CD07805/47 placebo
Intervention descriptions: intervention 1: 0.5% Topical Gel intervention 2: 0.18% Topical Gel intervention 3: 0.07% Topical Gel intervention 4: Vehicle Topical Gel

Protocol document: