Conditions: Diabetes Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 182
Healthy volunteers: no

Brief summary:
This trial is conducted in Europe. The aim of this trial is to compare two NN5401 (Soluble Insulin Analogue Combination \[SIAC\], insulin degludec/insulin aspart) formulations with each other and with biphasic insulin aspart 30, all in combination with metformin in insulin naive subjects with type 2 diabetes.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: insulin degludec/insulin aspart intervention 2: insulin degludec/insulin aspart intervention 3: biphasic insulin aspart intervention 4: metformin
Intervention descriptions: intervention 1: Formulation B: Treat-to-target dose titration scheme, injection s.c., twice daily intervention 2: Formulation B: Treat-to-target dose titration scheme, injection s.c., twice daily intervention 3: Treat-to-target dose titration scheme, injection s.c., twice daily intervention 4: Tablets, 1500-2000 mg/daily

Protocol document: