Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1172
Healthy volunteers: no

Brief summary:
The purpose of this investigational study is to determine the safety and effectiveness of an investigational drug in patients with type 2 diabetes mellitus (a specific type of diabetes).

Detailed description:
The duration of treatment is 104 weeks.

Arms:
arm 1: Sitagliptin 100 mg oral tablets of sitagliptin once daily. arm 2: Glipizide 1 tablet (5 mg) per day. Patients could then up-titrated to a total daily dose of 4 tablets twice daily (20mg/day) based on their glycemic control.

Interventions: intervention 1: sitagliptin (MK0431) intervention 2: Comparator: glipizide
Intervention descriptions: intervention 1: Sitagliptin 100 mg oral tablets of sitagliptin once daily. intervention 2: Glipizide 1 tablet (5 mg) per day. Patients could then up-titrated to a total daily dose of 4 tablets twice daily (20mg/day) based on their glycemic control.

Protocol document: