Conditions: Alzheimer's Disease
Keywords: Alzheimer's disease
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 199
Healthy volunteers: no

Brief summary:
This study attempts to differentiate the clinical responses of Choline Acetyltransferase and Apolipoprotein Epsilon gene polymorphism to donepezil in Alzheimer's Disease patients.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Donepezil
Intervention descriptions: intervention 1: 2.5mg once daily for the first 7 days, 5mg once daily for the next 3 weeks, after then the dose can be increased 10mg once daily under the investigator's decision.

Protocol document: