Conditions: Pulmonary Hypertension
Keywords: primary pulmonary hypertension secondary pulmonary hypertension due to left heart failure secondary pulmonary hypertension due to other causes patients without pulmonary disease or pulmonary hypertension
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 38
Healthy volunteers: yes

Brief summary:
The purpose of the study is is to determine the effect, on the lung circulation, of BQ-123, an investigational compound which is not approved by the FDA.

Detailed description:
Endothelin levels are increased in patients with pulmonary hypertension. We wish to compare the effect of an endothelin antagonist on pulmonary hypertension due to a variety of causes.

Arms:
arm 1: BQ-123

Interventions: intervention 1: BQ-123
Intervention descriptions: intervention 1: 6-120 µg/min

Protocol document: