Conditions: Leukemia
Keywords: B-cell chronic lymphocytic leukemia stage I chronic lymphocytic leukemia stage II chronic lymphocytic leukemia stage III chronic lymphocytic leukemia stage IV chronic lymphocytic leukemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 817
Healthy volunteers: no

Brief summary:
This randomized phase III trial is studying fludarabine, cyclophosphamide, and rituximab to see how well they work compared to fludarabine and cyclophosphamide in treating patients with B-cell chronic lymphocytic leukemia.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Rituximab intervention 2: Cyclophosphamide intervention 3: Fludarabine Phosphate
Intervention descriptions: intervention 1: Intravenous repeating dose intervention 2: Intravenous repeating dose intervention 3: Intravenous repeating dose

Protocol document: