Conditions: Postmenopause
Keywords: Biomarkers of estrogen receptor beta activation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 27
Healthy volunteers: yes

Brief summary:
This study will develop a model for the assessment of successful activation/engagement of estrogen receptor beta using salivary biomarkers.

Detailed description:

Arms:
arm 1: Placebo arm 2: Estrace 0.5 mg arm 3: Estrace 2 mg

Interventions: intervention 1: Comparator: placebo intervention 2: Comparator: Estrace
Intervention descriptions: intervention 1: placebo capsule once daily for 7 days. intervention 2: Estrace 0.5 mg or 2 mg tablets once daily for 7 days.

Protocol document: