Conditions: Postoperative Pain Abdominal Surgery
Keywords: Postoperative pain Post-operative pain Opioid Laparoscopic surgery Bupivacaine Local anesthetic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 331
Healthy volunteers: no

Brief summary:
This is a research study testing SABER-Bupivacaine (an experimental pain-relieving medication). SABER-Bupivacaine is designed to continuously deliver bupivacaine, a common local anesthetic, for a few days in order to treat local post-surgical pain.

The purpose of this study is to investigate safety (side effects) associated with the use of SABER-Bupivacaine and how well it works in reducing pain and opioid-related side effects following various kinds of abdominal surgeries.

Detailed description:

Arms:
arm 1: SABER-Bupivacaine arm 2: Bupivacaine HCl arm 3: SABER-Placebo

Interventions: intervention 1: SABER-Bupivacaine intervention 2: Bupivacaine HCl intervention 3: SABER-Placebo
Intervention descriptions: intervention 1: Injectable Extended Release Solution; SABER-Bupivacaine /Once intervention 2: Injectable Solution; Bupivacaine HCl /Once intervention 3: Injectable Solution; SABER-Placebo/Once

Protocol document: