Conditions: Anesthesia, General Neuromuscular Blockade
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 164
Healthy volunteers: no

Brief summary:
The present trial is set up to evaluate the efficacy and safety of 4.0 mg.kg-1 sugammadex in Chinese and Caucasian subjects for registration purposes in China.

Detailed description:

Arms:
arm 1: At 1-2 post-tetanic counts (PTC) after the last dose of rocuronium, 4.0 mg.kg-1 sugammadex was to be administered. Caucasian subjects living in Europe. arm 2: At 1-2 post-tetanic counts (PTC) after the last dose of rocuronium, 4.0 mg.kg-1 sugammadex was to be administered. Chinese subjects living in China.

Interventions: intervention 1: Sugammadex
Intervention descriptions: intervention 1: After induction of anesthesia an intubation dose of 0.6 mg/kg rocuronium was to be administered. Maintenance doses of 0.1-0.2 mg/kg rocuronium intravenous (IV) could have been administered if necessary. At 1-2 PTC after the last administration of rocuronium, an IV single bolus dose of 4.0 mg/kg sugammadex was to be administered.

Protocol document: