Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Symbicort Oxis Chronic Obstructive Pulmonary Disease COPD Efficacy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1293
Healthy volunteers: no

Brief summary:
The primary purpose of the study is to investigate if Symbicort is more effective than Oxis in increasing forced expiratory volume in one second (FEV1), measured at the clinics, in patients with COPD.

Detailed description:

Arms:
arm 1: Symbicort Turbuhaler 160/4.5 microgram, 2 inhalations twice daily arm 2: Oxis Turbuhaler 4.5 microgram, 2 inhalations twice daily

Interventions: intervention 1: Budesonide/formoterol (Symbicort Turbuhaler) intervention 2: Formoterol (Oxis Turbuhaler)
Intervention descriptions: intervention 1: 2x160/4.5 microgram, inhalation, twice daily, 12 weeks intervention 2: 2 X 4.5 microgram, inhalation, twice daily, 12 weeks

Protocol document: