Conditions: Healthy
Keywords: Healthy volunteers
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 38
Healthy volunteers: yes

Brief summary:
This is a drug-drug interaction study; the purpose of this study is to examine the pharmacokinetics (levels of drug in the blood) of SPD503 (guanfacine hydrochloride) and Concerta (methylphenidate HCl) when given alone, and in combination.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: SPD503 intervention 2: Concerta intervention 3: SPD503 + Concerta
Intervention descriptions: intervention 1: SPD503 (guanfacine hydrochloride) extended-release 4 mg orally administered tablets intervention 2: CONCERTA (methylphenidate HCl) extended-release 36 mg orally administered tablets. intervention 3: SPD503 4 mg + CONCERTA 36 mg orally administered tablets (taken together).

Protocol document: