Conditions: Postoperative Pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 80
Healthy volunteers: no

Brief summary:
To the investigators' knowledge, no study has looked at differences in postoperative pain when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and propofol in laparoscopic cholecystectomy. The investigators' hypothesis is that total intravenous anesthesia with propofol will lead to less postoperative pain in the first 24 hours after laparoscopic cholecystectomy when compared to maintenance of anesthesia with isoflurane, desflurane or sevoflurane.

PURPOSE

To find out if maintenance of anesthesia with propofol leads to less postoperative pain after laparoscopic cholecystectomy when compared to maintenance of anesthesia with isoflurane, desflurane, or sevoflurane.

Detailed description:

Arms:
arm 1: General Anesthesia with Desflurane arm 2: General Anesthesia with Sevoflurane arm 3: General Anesthesia with Isoflurane arm 4: General Anesthesia with Propofol

Interventions: intervention 1: Desflurane intervention 2: Sevoflurane intervention 3: Isoflurane intervention 4: Propofol
Intervention descriptions: intervention 1: Patient induced for general anesthesia as per standard protocol and maintenance of anesthesia provided with Desflurane intervention 2: Patient induced for general anesthesia as per standard protocol and maintenance of anesthesia provided with Sevoflurane intervention 3: Patient induced for general anesthesia as per standard protocol and maintenance of anesthesia provided with Isoflurane intervention 4: Patient induced for general anesthesia as per standard protocol and maintenance of anesthesia provided with intravenous Propofol infusion

Protocol document: