Conditions: Reflux Episodes
Keywords: GERD transient lower esophageal sphincter relaxations (TLESRs) reflux
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 27
Healthy volunteers: no

Brief summary:
The purpose of the study is to compare frequency and content of reflux episodes in patients with gastroesophageal reflux disease.

Detailed description:

Arms:
arm 1: AZD3355 arm 2: None

Interventions: intervention 1: AZD3355 intervention 2: Placebo
Intervention descriptions: intervention 1: 65 mg capsules, oral, 3 single doses intervention 2: capsules, oral, 3 single doses

Protocol document: