Conditions: Rheumatoid Arthritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 151
Healthy volunteers: no

Brief summary:
Multi-center, parallel-group, randomized, open control study. All patients will be selected to two treatment groups.

1. Etanercept alone treatment group (25mg, twice/week, s.c.)
2. Etanercept combined with MTX group (25mg, twice/week, s.c.+MTX 6-8mg/week)

Detailed description:

Arms:
arm 1: etanercept (25mg, twice/week, s.c.) arm 2: etanercept (25mg, twice/week, s.c.) combined with methotrexate (6-8mg/week)

Interventions: intervention 1: ETN Alone intervention 2: ETN+MTX
Intervention descriptions: intervention 1: etanercept (25 mg, twice/week, s.c.) intervention 2: etanercept (25 mg, twice/week, s.c.) combined with methotrexate (6-8 mg/week)

Protocol document: