Conditions: Psoriasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 199
Healthy volunteers: no

Brief summary:
The study was double-blind, randomized, vehicle-controlled study with application of Ruxolitinib phosphate cream or vehicle cream in participants with stable plaque psoriasis applied once daily for 12 weeks without occlusive dressings. There were 4 treatment groups anticipated to have 50 participants in each.

Detailed description:

Arms:
arm 1: Vehicle cream, applied topically, once daily from Day 1 to Week 12. arm 2: Ruxolitinib phosphate 0.5% cream, applied topically, once daily from Day 1 to Week 12. arm 3: Ruxolitinib phosphate 1.0% cream, applied topically, once daily from Day 1 to Week 12. arm 4: Ruxolitinib phosphate 1.5% cream, applied topically, once daily from Day 1 to Week 12.

Interventions: intervention 1: Placebo Cream intervention 2: Ruxolitinib Phosphate
Intervention descriptions: intervention 1: Cream with no active drug intervention 2: Ruxolitinib phosphate cream

Protocol document: