Conditions: Irritable Bowel Syndrome With Constipation
Keywords: Irritable Bowel Syndrome with Constipation IBS Irritable Bowel Syndrome linaclotide acetate linaclotide MD-1100
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 420
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the safety, efficacy, and dose response of a range of oral doses of linaclotide administered to patients meeting criteria for IBS-C.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None

Interventions: intervention 1: Linaclotide Acetate intervention 2: Matching placebo
Intervention descriptions: intervention 1: Oral, once daily intervention 2: Oral, once daily

Protocol document: