Conditions: HIV Infections
Allocation:  | Intervention model: PARALLEL
Enrollment: 882
Healthy volunteers: no

Brief summary:
The objective of this study is to demonstrate the safety and efficacy of tipranavir/ritonavir versus an active control arm in highly treatment experienced Human immunodeficiency virus-1 infected patients. Patients must have a viral load \> =1000 cells/mL, and genotype indicating at least one resistance conferring protease inhibitor-mutation as determined from a predefined panel of mutations. Any CD4+ count is acceptable.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Tipranavir (with low dose ritonavir) intervention 2: Comparator protease inhibitor(CPI)/low dose ritonavir(r)
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: