Conditions: Nicotine Dependence
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 246
Healthy volunteers: yes

Brief summary:
The purpose of this study is designed to examine the effects of Selegiline Transdermal System and behavioral intervention in smoking cessation as compared to behavioral intervention alone.

Detailed description:

Arms:
arm 1: Subjects were evaluated for their compliance with protocol inclusion/exclusion criteria during a -4 week Screening/Baseline Phase.

During treatment, subjects received Selegiline Transdermal System, 6mg -20cm(2) patch, one time per day for 9 weeks

Subjects were provided with on-site, individual smoking cessation counseling sessions 1x per week for 9 weeks arm 2: Subjects were evaluated for their compliance with protocol inclusion/exclusion criteria during a -4 week Screening/Baseline Phase.

During treatment, subjects received matched placebo 20cm(2) patch transdermal patch one time per day for 9 weeks

Subjects were provided with on-site, individual smoking cessation counseling sessions 1x per week for 9 weeks

Interventions: intervention 1: Selegiline Transdermal Patch intervention 2: Placebo intervention 3: Smoking Cessation Counseling
Intervention descriptions: intervention 1: Selegiline cm(2) via transdermal system intervention 2: Matching placebo via transdermal system intervention 3: Subjects were provided with on-site, individual smoking cessation counseling sessions 1x per week for 9 weeks

Protocol document: