Conditions: Urogential Chlamydia Trachomatis Infection
Keywords: Chlamydia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 495
Healthy volunteers: no

Brief summary:
Evaluate the clinical efficacy and safety of WC2031 200 mg tablets taken orally once a day for 7 days versus Vibramycin (doxycycline) 100 mg capsules taken orally twice a day for 7 days, for the treatment of uncomplicated urogenital Chlamydia trachomatis infection. Primary efficacy endpoint is microbiological cure at Day 28. Safety assessments are adverse events, changes in vital signs and laboratory test results.

Detailed description:

Arms:
arm 1: Once daily arm 2: Twice daily

Interventions: intervention 1: Doxycyline Hyclate tablet intervention 2: Vibramycin (doxycyline hyclate) capsule
Intervention descriptions: intervention 1: 200 mg tablet, once daily for 7 days intervention 2: 100 mg capsule, twice daily for 7 days, over-encapsulated

Protocol document: