Conditions: Hypercholesterolemia Coronary Arteriosclerosis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 22
Healthy volunteers: no

Brief summary:
This study is being conducted to compare the efficacy, safety, and tolerability of ezetimibe 10 mg coadministered with atorvastatin 10 mg versus atorvastatin 10 mg in Indonesian population with primary hypercholesterolemia.

Detailed description:

Arms:
arm 1: Participants treated with 10 mg/day ezetimibe added to an ongoing treatment of 10 mg/day atorvastatin. arm 2: Participants treated with 10 mg/day matching placebo to ezetimibe added to an ongoing treatment of 10 mg/day atorvastatin.

Interventions: intervention 1: Ezetimibe intervention 2: Placebo intervention 3: Atorvastatin 10 mg
Intervention descriptions: intervention 1: 10 mg ezetimibe, orally, daily for 6 weeks, added to ongoing treatment with 10 mg atorvastatin intervention 2: 10 mg/day matching placebo to ezetimibe, orally, daily for 6 weeks, added to ongoing 10 mg atorvastatin intervention 3: 10 mg/day atorvastatin, orally, (ongoing treatment in participants)

Protocol document: