Conditions: Stage 2 Hypertension
Keywords: Hypertension, aliskiren and valsartan
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 451
Healthy volunteers: no

Brief summary:
To evaluate the efficacy and safety of the valsartan/aliskiren combination compared to valsartan alone in patients with Stage 2 hypertension.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Valsartan/aliskiren intervention 2: Valsartan
Intervention descriptions: intervention 1: Valsartan/aliskiren (160/150mg) for 2 weeks followed by forced titration to valsartan/aliskiren (320/300mg) for the remaining 6 weeks intervention 2: Valsartan (160mg) for 2 weeks followed by forced titration to Valsartan (320mg) for the remaining 6 weeks

Protocol document: