Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 344
Healthy volunteers: no

Brief summary:
This study is designed to look at how best to start and then gradually intensify (as needed) the insulin lispro premix regimen in type 2 diabetes patients who consume a light breakfast.

Detailed description:

Arms:
arm 1: Glargine +/- 1,2 or 3 injections of insulin lispro plus oral antihyperglycemic medications (OAMs) arm 2: Premixed Insulin Lispro (mid-mixture or low-mixture) 1,2 or 3 injections plus OAMs

Interventions: intervention 1: Insulin Glargine intervention 2: Insulin Lispro Premix (mid-mixture and low-mixture)
Intervention descriptions: intervention 1: patient glucose-level dependent, injection, as needed per patient glucose level, 48 weeks intervention 2: patient glucose level dependent, injection, as needed per patient glucose level, 48 weeks

Protocol document: