Conditions: Glaucoma Ocular Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 148
Healthy volunteers: no

Brief summary:
A three-month evaluation comparing the safety and efficacy of a fixed combination of 0.2% brimonidine tartrate/0.5% timolol maleate with that of latanoprost 0.005%, a prostaglandin analogue in glaucoma or ocular hypertension subjects

Detailed description:

Arms:
arm 1: Fixed combination of brimonidine tartrate 0.2%/timolol maleate 0.5% ophthalmic solution arm 2: Latanoprost 0.005% ophthalmic solution

Interventions: intervention 1: fixed combination of brimonidine tartrate 0.2% timolol maleate 0.5% ophthalmic solution intervention 2: latanoprost 0.005%
Intervention descriptions: intervention 1: 1 drop of study medication taken approximately 12 hours apart, dosed 2 times a day intervention 2: 1 drop of study medication taken once daily

Protocol document: