Conditions: Major Depressive Disorder
Keywords: Single or recurrent non-psychotic episode of Major Depressive Disorder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 349
Healthy volunteers: no

Brief summary:
The purpose of this 14 week, randomized, double-blind, placebo controlled study is to assess the safety and efficacy of aripiprazole to placebo as adjunctive treatment to an assigned open-label marketed antidepressant therapy (ADT) in patients with Major Depressive Disorder who demonstrate an incomplete response to a prospective eight week trial of the same assigned open-label marketed antidepressant therapy.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Aripiprazole+ ADT intervention 2: Placebo+ ADT
Intervention descriptions: intervention 1: Tablets, Oral, 2 - 20 mg variable dose once daily, 14 weeks intervention 2: Tablets, Oral, 2 - 20 mg variable dose once daily, 14 weeks

Protocol document: