Conditions: Dry Eye Syndromes
Keywords: Dry eye
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 327
Healthy volunteers: no

Brief summary:
A prospective, randomized, placebo and active comparator controlled study of CP-690,550 in subjects with dry eye.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None arm 6: None

Interventions: intervention 1: CP-690,550 intervention 2: CP-690,550 intervention 3: CP-690,550 intervention 4: CP-690,550 intervention 5: Cyclosporine intervention 6: CP-690,550 Vehicle
Intervention descriptions: intervention 1: Ophthalmic topical solution, low dose, dosed at least once/day, 8 weeks intervention 2: Ophthalmic topical solution, medium dose, dosed at least once/day, 8 weeks intervention 3: Ophthalmic topical solution, intermediate dose, dosed at least once/day, 8 weeks intervention 4: Ophthalmic topical solution, high dose, dosed at least once/day, 8 weeks intervention 5: Ophthalmic topical solution, 0.05%, dosed at least once/day, 8 weeks intervention 6: Ophthalmic topical solution, dosed at least once/day, 8 weeks

Protocol document: