Conditions: Scleritis Orbital Disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 20
Healthy volunteers: no

Brief summary:
The purpose of this study is to assess the safety and tolerability of Rituximab in refractory scleritis and non-infectious orbital inflammation.

Detailed description:

Arms:
arm 1: Subjects with Scleritis arm 2: Subjects with Orbital Inflammation

Interventions: intervention 1: Rituximab
Intervention descriptions: intervention 1: Two 500 or 1000mg infusions over 2 weeks with the option of retreating after 6 months if initial improvement was seen.

Protocol document: