Conditions: Mesothelioma
Keywords: Mesothelioma inoperable relapsed
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 25
Healthy volunteers: no

Brief summary:
A clinical study to assess if a new investigational drug is effective in treating malignant mesothelioma, compared to a chemotherapy treatment (Navelbine®). In this study the patients will be assigned by chance to receive either the new drug or a chemotherapy treatment (Navelbine®). Treatment will continue as long as the cancer does not worsen and the patient wishes to continue in the study. The study will recruit approximately 66 patients.

Detailed description:

Arms:
arm 1: Vinorelbine arm 2: Vandetanib

Interventions: intervention 1: Vinorelbine intervention 2: Vandetanib
Intervention descriptions: intervention 1: None intervention 2: once daily oral dose

Protocol document: