Conditions: Hypertension
Keywords: Children pediatrics High Blood Pressure Hypertension Valsartan
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 74
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the safety and efficacy of three doses of valsartan (0.25, 1.0, and 4.0 mg/kg) on mean sitting systolic blood pressure (MSSBP) and mean sitting diastolic blood pressure (MSDBP) in 6 months - 5 year old children with hypertension (sitting systolic blood pressure \[SSBP\] ≥ 95th percentile ).

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Valsartan 0.25 mg/kg intervention 2: Valsartan 1.0 mg/kg intervention 3: Valsartan 4.0 mg/kg
Intervention descriptions: intervention 1: once daily intervention 2: once daily intervention 3: once daily

Protocol document: