Conditions: Labor Augmentation
Keywords: Labor augmentation Oral misoprostol
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 350
Healthy volunteers: yes

Brief summary:
This is a prospective, randomized, controlled trial designed to examine the efficacy of oral misoprostol for labor augmentation compared to a standard regimen of intravenous oxytocin.

Detailed description:

Arms:
arm 1: Women with hypotonic labor and a clinical decision to proceed with labor augmentation will receive intravenous oxytocin. arm 2: Women with hypotonic labor and a clinical decision to proceed with labor augmentation will receive oral misoprostol.

Interventions: intervention 1: Misoprostol intervention 2: Oxytocin
Intervention descriptions: intervention 1: 75 micrograms orally every 4 hours for up to 2 doses. intervention 2: Intravenous oxytocin will be administered per the established Labor and Delivery protocol at Parkland Memorial Hospital

Protocol document: