Conditions: Healthy
Keywords: healthy volunteers
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 322
Healthy volunteers: yes

Brief summary:
To evaluate the safety and tolerability of raxibacumab in healthy subjects.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: placebo intervention 2: raxibacumab intervention 3: placebo intervention 4: raxibacumab
Intervention descriptions: intervention 1: 40 mg/kg intravenously, double dose (day 0 and 14), Group 3 intervention 2: 40 mg/kg intravenously, double dose (day 0 and 14), Group 1 intervention 3: 40 mg/kg placebo, single dose (day 0), Group 4 intervention 4: 40 mg/kg intravenously, single dose, day 0, Group 2

Protocol document: