Conditions: Diabetes Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 441
Healthy volunteers: no

Brief summary:
This trial is conducted in Asia. The trial aims to investigate if the blood glucose control of biphasic insulin aspart 50 is at least as effective as treatment with biphasic insulin aspart 30 both in combination with metformin.

Detailed description:

Arms:
arm 1: Biphasic insulin aspart 50 administered before breakfast and lunch + biphasic insulin aspart 30 at dinner combined with metformin arm 2: Biphasic insulin aspart 30 administered before breakfast and dinner combined with metformin

Interventions: intervention 1: biphasic insulin aspart 30 intervention 2: metformin intervention 3: biphasic insulin aspart 50
Intervention descriptions: intervention 1: Treat-to-target dose titration scheme (dose adjusted individually), s.c. (under the skin) injection before dinner intervention 2: Tablets, 500 - 2000 mg, once, twice or three times daily intervention 3: Treat-to-target dose titration scheme (dose adjusted individually), s.c. (under the skin) injection before breakfast and lunch

Protocol document: