Conditions: Post Operative Anterior Chamber Inflammation (Flare)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: yes

Brief summary:
Approximately 50 patients undergoing cataract surgery will be randomized in an even allocation (1:1) into two treatment groups, either ketorolac 0.45% BID or bromfenac 0.09% BID. Patients will be instructed to begin dosing study medication in the operative eye the day before surgery and continue dosing until day 14. KOWA flare measurements will be performed at postoperative day one and postoperative day 14. The amount of anterior chamber inflammation (flare) will be objectively measured.

Detailed description:

Arms:
arm 1: bromfenac 0.09% drops to be given pre operatively for one day BID, and then postoperatively for 14 days. arm 2: Acuvail to be given preoperatively at BID for one day pre op and then post operatively for 14 days.

Interventions: intervention 1: Ketorolac Tromethamine 0.45% intervention 2: Bromfenac 0.09%
Intervention descriptions: intervention 1: Acuvail to be given 1 drop BID for one day prior to surgery and then 1 drop BID post operatively for 14 days. intervention 2: Drug given one drop BID for one day pre operatively and then BID for 14 days post operatively

Protocol document: