Conditions: Head and Neck Cancer
Keywords: Head and Neck Cancer Advanced Inoperable Head & Neck Cancer
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 3
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine if RAD001, to a maximum dose of 10 mg/day, can be safely administered with cisplatin, and concurrent radiotherapy, for patients with locally advanced, inoperable, squamous cell carcinoma of the head and neck.

Detailed description:
To perform a phase I study of RAD001, to a maximum dose of 10 mg/day, with cisplatin, and concurrent radiotherapy, for patients with locally advanced, inoperable, squamous cell carcinoma of the head and neck

Arms:
arm 1: Radiation 47 days Cisplatin day 1,8,15,22,29,36,43 RAD001 Day 1 according to assigned group to day 47

Interventions: intervention 1: RAD001(Afinitor)
Intervention descriptions: intervention 1: Rad001 in combination withCisplatin and Concurrent RT

Protocol document: