Conditions: Acute Coronary Syndrome (ACS)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 221
Healthy volunteers: no

Brief summary:
The purpose of this study is to demonstrate that patients receiving cangrelor infusion before coronary artery bypass grafting have an acceptable safety profile and can undergo surgery without excessive bleeding peri-operatively.

Detailed description:

Arms:
arm 1: Cangrelor was administered as a continuous IV infusion of 0.75µg/kg/min for a minimum of 48 hours and a maximum of 7 days. arm 2: A placebo infusion was administered as a continuous IV infusion of 0.75µg/kg/min for a minimum of 48 hours and a maximum of 7 days, to maintain the blind.

Interventions: intervention 1: cangrelor intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: Placebo IV infusion administered in the same fashion as the active study drug in order to maintain the blind in the study.

Protocol document: