Conditions: Dental Plaque
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 22
Healthy volunteers: yes

Brief summary:
Calibration study to determine the anit-plaque efficacy of commerical toothpastes and an oral rinse

Detailed description:
Training of new examiners and validation of new clinical site to run 4 day short-term plaque studies. All products are commercially available.

Arms:
arm 1: negative control toothpaste arm 2: positive control toothpaste (Total toothpaste) arm 3: positive control oral rinse

Interventions: intervention 1: Fluoride intervention 2: Triclosan, fluoride intervention 3: Chlorhexidine Gluconate
Intervention descriptions: intervention 1: Brush half mouth twice daily for four days. intervention 2: Brush twice daily intervention 3: Rinse mouth twice a day

Protocol document: