Conditions: Prostate Cancer
Keywords: Prostate Cancer Docetaxel 03-076
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 102
Healthy volunteers: no

Brief summary:
We postulate that multiple apoptototic events are indusce through testosterone depletion and repletion with taxotere given in conjunction with androgen withdrawal.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: GnRh (Leuprolide) intervention 2: Testosterone Gel intervention 3: Docetaxel
Intervention descriptions: intervention 1: Leuprolide LUPRON intervention 2: Starting during week 3 (day 19) of cycle 1, 7.5G applied topically daily for 3 days (applied at approximately 9p) intervention 3: 70 mg/m2 given on day o1 of each 3 week cycle

Protocol document: