Conditions: End-Stage Renal Disease Hemodialysis
Keywords: CP-690 550 pharmacokinetics end-stage renal disease
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: no

Brief summary:
There were 2 study periods in this study. In the Period 1, CP-690,550 was to be administered approximately 1 to 2 hours following hemodialysis. If significant non-renal clearance of the drug occurred such that dialyzability of CP-690,550 could not be assessed in Period 1, a second period (Period 2) will be conducted. In Period 2, a single dose of drug will be administered approximately 4 hours prior to hemodialysis.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: CP-690,550
Intervention descriptions: intervention 1: CP-690,550 10 mg oral powder for constitution

Protocol document: