Conditions: Postmenopausal Osteoporosis
Keywords: Osteoporosis Postmenopausal
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 332
Healthy volunteers: no

Brief summary:
This study will determine whether treatment with AMG 162 can prevent lumbar spine bone loss in both early and late postmenopausal women with osteopenia, and to further test the safety and tolerability of AMG 162 in this population.

Detailed description:

Arms:
arm 1: 60 mg/mL denosumab given day 1, month 6, month 12 and month 18 arm 2: Placebo given day 1, month 6, month 12 and month 18

Interventions: intervention 1: AMG 162 intervention 2: Placebo
Intervention descriptions: intervention 1: 60 mg/mL denosumab given day 1, month 6, month 12 and month 18 intervention 2: Placebo given at day 1, month 6, month 12 and month 18

Protocol document: