Conditions: Infection
Keywords: Complicated Intra-Abdominal Infections
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 804
Healthy volunteers: no

Brief summary:
A study to compare the safety and efficacy of moxifloxacin to ertapenem in patients with intra-abdominal infections.

Detailed description:

Arms:
arm 1: Subjects received placebo matching the comparator (Ertapenem dummy) and Moxifloxacin 400 mg in 250 mL for intravenous infusion every 24 hours. arm 2: Subject received Ertapenem 1.0 g in 50 mL for intravenous infusion and placebo matching Moxifloxacin (Moxifloxacin dummy) every 24 hours.

Interventions: intervention 1: Moxifloxacin (Avelox, BAY12-8039) intervention 2: Ertapenem intravenous
Intervention descriptions: intervention 1: Moxifloxacin, 400mg, administered intravenously once daily intervention 2: Active treatment: Ertapenem 1.0g, administered intravenously once daily

Protocol document: