Conditions: Postoperative Pain
Keywords: Pain Post Operative Opioids Laparoscopic Surgery Hysterectomy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 75
Healthy volunteers: no

Brief summary:
The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the dorsal rami of L1-3 are blocked with an injection of local anesthetic between the internal oblique abdominal muscle (IOAM) and the transverse abdominal muscle(TAM)This technique allows sensory blockade of the anterolateral abdominal wall via local anesthetic deposition superficial to the transversus abdominis muscle. It was first described by McDonnell et al. as a landmark technique to provide analgesia for lower abdominal surgery.

Hebbart et al. subsequently described an ultrasound guided technique for the TAP block which they named posterior TAP block. The ultrasound allows identification of the external oblique abdominal muscles (EOAM),IOAM and TAM. Previous studies about ultrasound -guided regional anesthetic techniques suggest improved block quality and safety, which is primarily due to direct visualization of the relevant anatomy, the tip of the needle, and the spread of the local anesthetics.

Clinical trials of the single shot posterior TAP block have shown a significant reduction in morphine consumption during the first 24-36 hours after surgery. More recently, El-dawlatly et al. demonstrated that ultrasound guided TAP block in patients undergoing laparoscopic cholecystectomy reduced perioperative opioid consumption by more than 50%.

This is the first study to evaluate the effect of TAP block in the quality of recovery in patients undergoing laparoscopic hysterectomy and may help the pathway to make this an outpatient procedure.

Detailed description:

Arms:
arm 1: sterile normal saline as placebo arm 2: Instillation of 20 cc of 0.5% ropivacaine arm 3: Instillation of 20 cc of 0.25% ropivacaine

Interventions: intervention 1: Placebo intervention 2: Drug .5% Ropivacaine intervention 3: 20 cc of 0.25% ropivacaine
Intervention descriptions: intervention 1: placebo injection intervention 2: .5% ropivacaine 20 mls on each side of abdomen intervention 3: Will receive a bilateral TAP block using 20 cc of 0.25% ropivacaine

Protocol document: