Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 131
Healthy volunteers: no

Brief summary:
Test the safety, tolerability and improvement of blood sugar control with combination therapy in individuals with Type 2 Diabetes.

Detailed description:

Arms:
arm 1: Weekly LY2428757 plus 3 milligrams (mg) daily TT223 arm 2: Weekly LY2428757 plus 2 mg daily TT223 arm 3: Weekly LY2428757 plus daily TT223 placebo arm 4: Weekly LY2428757 placebo plus daily TT223 placebo

Interventions: intervention 1: LY2428757 intervention 2: TT223 intervention 3: Placebo for LY2428757 intervention 4: Placebo for TT223
Intervention descriptions: intervention 1: 14 mg subcutaneous injection 1 time a week for 5 weeks intervention 2: subcutaneous injection once a day for 4 weeks intervention 3: subcutaneous injection 1 time a week for 5 weeks intervention 4: subcutaneous injection once a day for 4 weeks

Protocol document: