Conditions: Bacterial Conjunctivitis
Keywords: Bacterial Conjunctivitis Pink Eye Conjunctivitis Eye Infection
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 743
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the clinical and microbial efficacy and safety of AzaSite compared to tobramycin for bacterial conjunctivitis. Adults and children one year of age and older with bacterial conjunctivitis in at least one eye are eligible. Subjects will be randomly assigned to the AzaSite group or Tobramycin group. Three visits will be required for the study.

Detailed description:

Arms:
arm 1: 1.0% azithromycin in DuraSite arm 2: 0.3% tobramycin

Interventions: intervention 1: AzaSite intervention 2: Tobramycin
Intervention descriptions: intervention 1: AzaSite ophthalmic solution; one topical drop to the infected eye or eyes twice daily (in the morning and at bedtime) on Days 1 and 2 followed by once daily (in the morning between 7 and 10am) on Days 3 through 5. intervention 2: Tobramycin ophthalmic solution; one topical drop to the infected eye or eyes four times daily at 4 to 6 hour intervals (first dose in the morning between 7 and 10am) for 5 days.

Protocol document: