Conditions: Primary Open Angle Glaucoma Ocular Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 117
Healthy volunteers: no

Brief summary:
To investigate dose response, safety and efficacy of PF-03187207 in patients with primary open-angle glaucoma or ocular hypertension

Detailed description:

Arms:
arm 1: A single drop of each, once daily in study eye for 28 days arm 2: A single drop of each, once daily in study eye for 28 days arm 3: A single drop of each, once daily in study eye for 28 days arm 4: A single drop of each, once daily in study eye for 28 days

Interventions: intervention 1: PF-03187207 intervention 2: Latanoprost 0.005% intervention 3: PF-03187207 Vehicle intervention 4: Latanoprost Vehicle
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: One drop in study eye once daily for the first 28 days to all subjects, followed by 28 days in combination with PF-03187207. intervention 4: None

Protocol document: