Conditions: Postmenopausal Symptoms
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 29
Healthy volunteers: yes

Brief summary:
The purpose of this study is to examine the effect of two different dose levels of estrogen or placebo in healthy postmenopausal women by measuring the changes in hormone levels and examining the changes in the uterine lining (endometrium).

Detailed description:

Arms:
arm 1: Estrace 2.0 mg tablet arm 2: Estrace 0.5 mg tablet arm 3: Placebo

Interventions: intervention 1: Comparator: Estrace 0.5 mg intervention 2: Comparator: Estrace 2 mg intervention 3: Comparator: Placebo
Intervention descriptions: intervention 1: 0.5 mg tablet taken once daily for 28 days intervention 2: 2 mg tablets taken once daily for 28 days. intervention 3: Placebo 0 mg capsule taken once daily for 28 days

Protocol document: