Conditions: Pulmonary Disease, Chronic Obstructive Exercise
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 519
Healthy volunteers: no

Brief summary:
The objective of this study is to evaluate the effects on exercise duration of 96 weeks treatment with 18 mcg tiotropium (Spiriva HandiHaler) daily as compared to placebo, in patients with COPD.

Detailed description:

Arms:
arm 1: Oral inhalation once daily of 18mcg tiotropium via handihaler arm 2: Oral inhalation once daily of placebo matching tiotropium via handihaler

Interventions: intervention 1: tiotropium 18 mcg intervention 2: Placebo
Intervention descriptions: intervention 1: Oral inhalation once daily of 18mcg tiotropium via handihaler intervention 2: Oral inhalation of once-daily placebo matching tiotropium via handihaler

Protocol document: