Conditions: Acne
Keywords: Acne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 243
Healthy volunteers: no

Brief summary:
The purpose of this study is to demonstrate the efficacy of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel compared to its Vehicle Gel as an acne maintenance treatment in Subjects previously treated with Adapalene-BPO Gel or Adapalene-BPO Vehicle Gel both associated with Doxycycline Hyclate 100 mg. The safety of the two investigational treatments will also be assessed.

Detailed description:
This study is a follow-up to RD.03.SPR.29074 - ACCESS I / NCT00688064 - "Adapalene-BPO Gel Associated With Doxycycline 100 mg in the Treatment of Severe Acne Vulgaris"

Arms:
arm 1: Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel once daily arm 2: Vehicle Gel once daily

Interventions: intervention 1: Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel intervention 2: Vehicle Gel
Intervention descriptions: intervention 1: Topical Gel to the face, once daily in the evening for 24 weeks. intervention 2: Topical Gel to the face, once daily in the evening for 24 weeks.

Protocol document: