Conditions: Prostate Cancer
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 11
Healthy volunteers: no

Brief summary:
To determine the efficacy of soy/isoflavone supplementation on hot flashes in men who are being treated with luteinizing hormone-releasing hormone (LHRH) agonist therapy for control of advanced prostate cancer

Detailed description:
Literature has shown that low dose estrogens can control hot flashes in men on androgen deprivation but with a high risk of thromboembolic events. Soy derivatives that contain isoflavones, a type of phytoestrogen, have been evaluated in peri-menopausal women as a possible safer alternative to synthetic estrogens but there has not been a similar study performed on their effect in men on androgen deprivation therapy for prostate cancer.

Arms:
arm 1: Subjects receive supplement arm 2: Subjects will receive placebo

Interventions: intervention 1: Flav-ein capsules intervention 2: Placebo
Intervention descriptions: intervention 1: Soy/isoflavone supplementation intervention 2: Placebo

Protocol document: