Conditions: Macular Degeneration
Keywords: VEGF Trap-Eye Macular Degeneration AMD Neovascular Age-Related Macular Degeneration
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 157
Healthy volunteers: no

Brief summary:
Rollover study for subjects in prior VEGF Trap-Eye Phase I and II studies. Primary objective is to assess long-term safety and tolerability of continuing intravitreal treatment in subjects with wet age-related macular degeneration.

Detailed description:
Randomized, Single-Masked Phase II study for subjects previously enrolled in Phase I and II studies for wet age-related macular degeneration with VEGF Trap-Eye intravitreal injection as treatment.Long term (3 years) treatment is intended to measure safety and tolerability, as well as frequency of re-treatment and the effect of VEGF Trap-Eye on best corrected visual acuity (BCVA).

Arms:
arm 1: None

Interventions: intervention 1: VEGF Trap Eye
Intervention descriptions: intervention 1: Intravitreal injection

Protocol document: