Conditions: Healthy Subjects
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 30
Healthy volunteers: yes

Brief summary:
Characterize the relative pharmacokinetics (PK) of 3 marketed products containing guaifenesin

Detailed description:

Arms:
arm 1: Vicks Cough immediate-release (IR) syrup 15 mL (containing 200 mg guaifenesin) every 4 hours x 3 doses with 240 mL of water after an overnight fast arm 2: Robitussin Extra Strength Chest Congestion 5 ml (containing 200 mg guaifenesin) every 4 hours x 3 doses with 240 mL of water after an overnight fast arm 3: Organ-I- NR 200 mg guaifenesin tablet every 4 hours x 3 doses with 240 mL of water after an overnight fast

Interventions: intervention 1: Vicks Cough Syrup for Chesty Coughs intervention 2: Robitussin Extra Strength Chest Congestion intervention 3: Organ-I- NR tablet
Intervention descriptions: intervention 1: Vicks Cough Syrup for Chesty Coughs 15 mL (containing 200 mg guaifenesin) IR syrup with 240 mL of water intervention 2: Robitussin Extra Strength Chest Congestion 5 mL (containing 200 mg guaifenesin) IR syrup with 240 mL of water intervention 3: Organ-I- NR tablet (containing 200 mg guaifenesin) with 240 mL of water

Protocol document: