Conditions: Bipolar Disorder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 680
Healthy volunteers: no

Brief summary:
3-week study to evaluate efficacy and safety of ziprasidone with either lithium or divalproex in acutely manic subjects

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Placebo intervention 2: Ziprasidone intervention 3: Ziprasidone
Intervention descriptions: intervention 1: Placebo with mood stabilizer (either lithium or divalproex) intervention 2: Flexible dosing, 20-40mg BID, with a mood stabilizer (either lithium or divalproex) intervention 3: Flexible dosing, 60-80mg BID, with a mood stabilizer (either lithium or divalproex)

Protocol document: