Conditions: Rhinoconjunctivitis Rhinitis Conjunctivitis Allergy
Keywords: immunotherapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 203
Healthy volunteers: no

Brief summary:
The purpose of this study was to assess the safety and tolerability of a ragweed allergy immunotherapy tablet (AIT) administered sublingually (under-the tongue) in subjects 50 years of age and older with ragweed-induced rhinoconjunctivitis, with or without asthma.

Detailed description:

Arms:
arm 1: Matching placebo tablet sublingual, once daily arm 2: 6 Units Short Ragweed (Ambrosia artemisiifolia) Major Allergen 1 (Amb a 1-U) in an AIT, sublingual, once daily arm 3: 12 Amb a 1-U in an AIT, sublingual, once daily

Interventions: intervention 1: Placebo intervention 2: SCH 39641 intervention 3: SCH 39641
Intervention descriptions: intervention 1: Placebo sublingual tablet, once daily intervention 2: Allergy immunotherapy tablet (sublingual) intervention 3: Allergy immunotherapy tablet (sublingual)

Protocol document: