Conditions: Acute Pain Following a Total Abdominal Hysterectomy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 430
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy and safety of etoricoxib compared to placebo in the treatment of postoperative pain associated with total abdominal hysterectomy.

Detailed description:

Arms:
arm 1: etoricoxib (MK0663) 120 mg (2 60 mg tablets) and 1 placebo tablet once daily on Days 1-5. Total treatment is 5 days. arm 2: etoricoxib (MK0663) 90 mg tablet and 2 placebo tablets once daily on Days 1-5. Total treatment is 5 days. arm 3: Placebo- 3 tablets once daily

Interventions: intervention 1: etoricoxib (MK0663) 120 mg intervention 2: Comparator: Placebo intervention 3: etoricoxib (MK0663) 90 mg
Intervention descriptions: intervention 1: 120 mg of etoricoxib (MK0663) for a total of 5 days intervention 2: Placebo tablets once daily on Days 1-5. Total treatment is 5 days. intervention 3: 90 mg of etoricoxib (MK0663) for a total of 5 days

Protocol document: