Conditions: Attention Deficit Hyperactivity Disorder
Keywords: Brookhaven ADHD Dopamine methylphenidate PET
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 75
Healthy volunteers: yes

Brief summary:
The purpose of the study is to investigate the functional state of dopamine cells and the dopamine transporter in ADHD subjects and controls to assess the effects of chronic methylphenidate treatment on dopamine cell function and dopamine transporter levels in ADHD subjects.

Detailed description:

Arms:
arm 1: intervention is methylphenidate once daily for 12 months, doses individually titrated arm 2: no methylphenidate treatment for non ADHD

Interventions: intervention 1: Experimental: methylphenidate treatment
Intervention descriptions: intervention 1: subjects received mehtylphenidate treatment for 12 months

Protocol document: