Conditions: Hand-foot Skin Reaction Rash
Keywords: sorafenib rash hand foot skin reaction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 6
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate treatments for a rash caused by sorafenib.

Detailed description:
This study will compare compare the effectiveness of four creams (urea 40% cream, fluocinonide 0.05% cream, tazarotene 0.1% cream, and Udderly smooth® Udder Cream) in treating hand-foot skin reaction (HFSR), a rash caused by sorafenib.

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: urea 40% cream intervention 2: fluocinonide 0.05% cream intervention 3: tazarotene 0.1% cream intervention 4: bland emollient cream (Udderly smooth® Udder Cream)
Intervention descriptions: intervention 1: urea 40% cream applied twice per day to affected areas intervention 2: fluocinonide 0.05% cream applied twice per day to affected areas intervention 3: tazarotene 0.1% cream applied twice per day to affected areas intervention 4: bland emollient cream applied twice per day to affected areas

Protocol document: