Conditions: Skin and Subcutaneous Tissue Bacterial Infections
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 256
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare clinical response to the measurement techniques of several objective measures of clinical efficacy for use in future ABSSSI (Acute Bacterial Skin and Skin Structure Infection) clinical trials

Detailed description:

Arms:
arm 1: 300 mg IV (intravenous) every 12 hours for 5-14 days arm 2: 15 mg/kg, up to 1250 mg, IV every 12 hours for 5-14 dyas arm 3: 600 mg IV every 12 hours for 5-14 days

Interventions: intervention 1: Delafloxacin intervention 2: Linezolid intervention 3: Vancomycin
Intervention descriptions: intervention 1: 300mg IV every 12 hours for 5-14 days intervention 2: 600mg IV every 12 hours for 5-14 days intervention 3: 15mg/kg, up to 1250 mg, IV every 12 hours for 5-14 days

Protocol document: