Conditions: Obesity
Keywords: Obesity
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 676
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the long-term safety and efficacy of VI-0521 compared to placebo for the treatment of overweight and obesity in adults who have completed study OB-303 (NCT00553787) at selected study sites. This is an extension study of protocol OB-303 (NCT00553787).

Detailed description:

Arms:
arm 1: Placebo arm 2: 7.5 mg phentermine and 46 mg topiramate arm 3: 15 mg phentermine and 92 mg topiramate

Interventions: intervention 1: VI-0521 intervention 2: Placebo intervention 3: VI-0521
Intervention descriptions: intervention 1: 7.5 mg phentermine and 46 mg topiramate intervention 2: placebo intervention 3: 15 mg phentermine and 92 mg topiramate

Protocol document: