Conditions: Psoriasis
Keywords: psoriasis
Allocation: NON_RANDOMIZED | Intervention model: PARALLEL
Enrollment: 25
Healthy volunteers: no

Brief summary:
This will be an open label study of ruxolitinib topical cream applied to 2 - 20% BSA in patients with active, stable plaque psoriasis.

Detailed description:

Arms:
arm 1: Patients with active stable plaque psoriasis treated with topical cream application on lesions involving a small percent BSA. arm 2: Patients with active stable plaque psoriasis treated with topical cream application on lesions involving a larger percent BSA than Cohort 1. arm 3: Patients with active stable plaque psoriasis treated with topical cream application on lesions involving a larger percent BSA than Cohort 2.

Interventions: intervention 1: Ruxolitinib
Intervention descriptions: intervention 1: Ruxolitinib 1.5% cream BID for 28 days

Protocol document: