Conditions: Seasonal Allergic Rhinitis
Keywords: Nasal Decongestants Rhinitis, Allergic, Seasonal Rhinitis Nose Conditions Respiratory Tract Diseases Phenylephrine
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 575
Healthy volunteers: no

Brief summary:
This study will compare the nasal congestion symptom relief of phenylephrine extended release tablets and placebo in participants with allergic rhinitis.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Phenylephrine intervention 2: Placebo intervention 3: Loratadine
Intervention descriptions: intervention 1: Phenylephrine hydrochloride 30-mg extended-release tablets, one tablet every 12 hours for 7 days intervention 2: Placebo to phenylephrine hydrochloride 30-mg extended release tablets, one tablet every 12 hours for 7 days intervention 3: Loratadine, 10 mg, once daily as rescue medication, only if needed for intolerable allergic rhinitis symptoms

Protocol document: