Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 374
Healthy volunteers: no

Brief summary:
This study is designed to look at if a basal bolus regimen of insulin lispro protamine suspension (ILPS) provides the same glycemic control as a basal bolus regimen of insulin glargine (when one basal bolus regimen is injected once daily together with insulin lispro injected 2-3 times daily).

Detailed description:

Arms:
arm 1: Glargine plus Insulin Lispro (2-3 injections) arm 2: Insulin Lispro Protamine Suspension (ILPS) plus Insulin Lispro (2-3 injections)

Interventions: intervention 1: Insulin Glargine intervention 2: Insulin Lispro Protamine Suspension (ILPS) intervention 3: Insulin Lispro
Intervention descriptions: intervention 1: patient glucose-level dependent, injection, once daily in the evening, 24 weeks intervention 2: patient glucose-level dependent, injection, once daily in the evening, 24 weeks intervention 3: subcutaneous injections prior to meals, 24 weeks

Protocol document: