Conditions: Postoperative Dental Pain
Keywords: Postoperative Dental Pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 588
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain. Pain intensity and relief will be measured by the total pain relief score (TOPAR) and patient evaluation.

Detailed description:

Arms:
arm 1: etoricoxib 90 mg arm 2: etoricoxib 120 mg arm 3: ibuprofen 2400 mg arm 4: acetaminophen 2400 mg/codeine 240 mg arm 5: Matching Placebo

Interventions: intervention 1: Comparator: etoricoxib intervention 2: Comparator: ibuprofen intervention 3: Comparator: acetaminophen + codeine intervention 4: Comparator: placebo
Intervention descriptions: intervention 1: etoricoxib 90 mg; 120 mg (once daily) over three days. intervention 2: ibuprofen 2400 mg (600 mg Q6h) over three Days intervention 3: acetaminophen 2400 mg/codeine 240 mg (600/60 mg Q6h) over three Days intervention 4: matching placebo over three Days

Protocol document: