Conditions: Sleep Apnea
Keywords: Sleep apnea; obesity
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 45
Healthy volunteers: no

Brief summary:
The primary objectives of this study are to evaluate the safety and efficacy of VI-0521 compared to placebo in the treatment of obese adults with obstructive sleep apnea (OSA) and to assess the relative contributions of weight loss on parameters of OSA in these subjects.

Detailed description:

Arms:
arm 1: 15 mg Phentermine and 92 mg Topiramate arm 2: None

Interventions: intervention 1: VI-0521 intervention 2: placebo
Intervention descriptions: intervention 1: 15 mg Phentermine and 92 mg Topiramate intervention 2: placebo

Protocol document: