Conditions: Bowel Preparation for Colonoscopy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 191
Healthy volunteers: yes

Brief summary:
The primary outcomes of this procedure will be: 1. The cleanliness of the prep as measured by the Ottawa Scale (attachment a). Secondary outcomes will be: 1. Patient satisfaction with the prep measured by 5 point Likert scale (attachment b); 2. Procedure time; 3. The number and size of polyps detected on examination.

Detailed description:

Arms:
arm 1: split-dose PEG solution without dietary restrictions plus lubiprostone 24mcg gelcap pretreatment arm 2: split-dose PEG solution without dietary restrictions plus placebo pretreatment

Interventions: intervention 1: lubiprostone intervention 2: placebo
Intervention descriptions: intervention 1: lubiprostone 24mcg gelcap, 1 gelcap taken at noon the day prior to the colonoscopy intervention 2: placebo gelcap, taken at noon the day prior to the colonoscopy

Protocol document: