Conditions: Allergic Rhinitis Allergic Conjunctivitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 22
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the onset of action of fluticasone propionate nasal spray compared to placebo nasal spray in reducing nasal allergic signs and symptoms following ragweed exposure in the Allergen BioCube (ABC) after up to 14 days of at home dosing.

Detailed description:

Arms:
arm 1: Two sprays in each nostril daily starting the day in office on Day 0 for up to a 17 day period until Day 16. arm 2: Two sprays in each nostril daily starting the day in office on Day 0 for up to a 17 day period until Day 16.

Interventions: intervention 1: Fluticasone Propionate Nasal Spray intervention 2: Saline Nasal Spray
Intervention descriptions: intervention 1: two sprays in each nostril once daily intervention 2: two sprays in each nostril once daily

Protocol document: