Conditions: Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 16
Healthy volunteers: yes

Brief summary:
The objective of the current study is to determine the relative bioavailability of a BI 10773 / metformin fixed dose combination tablet compared to single tablets of BI 10773 and metformin when administered together and to assess the effect of food on the bioavailability the fixed dose combination tablet

Detailed description:

Arms:
arm 1: 3 treatments will be investigated in randomized order arm 2: 3 treatments will be investigated in randomized order arm 3: 3 treatments will be investigated in randomized order

Interventions: intervention 1: C: BI 10773 / metformin tablet intervention 2: B: BI 10773 tablet and metformin tablet intervention 3: A: BI 10773 / metformin tablet
Intervention descriptions: intervention 1: BI 10773 / metformin fixed dose combination tablet after a high fat, high caloric meal intervention 2: BI 10773 and metformin single tablets, administered together in fasted state intervention 3: BI 10773 / metformin fixed dose combination tablet in fasted state

Protocol document: