Conditions: Acne Vulgaris
Keywords: acne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 186
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate if topical ASC-J9 cream is effective in treating acne.

Detailed description:
Subjects with acne were randomized to one of four treatment groups for twice daily topical dosing to the face for 12 weeks. Assessments of acne status were performed at Baseline, Weeks 2, 4, 8 and 12 and then 4 weeks after the last dose of study drug.

Arms:
arm 1: Vehicle control cream applied topically to the face twice daily for 12 weeks arm 2: 0.001% ASC-J9 cream applied topically to the face twice daily for 12 weeks arm 3: 0.005% ASC-J9 cream applied topically to the face twice daily for 12 weeks arm 4: 0.025% ASC-J9 cream applied topically to the face twice daily for 12 weeks

Interventions: intervention 1: ASC-J9 cream intervention 2: placebo
Intervention descriptions: intervention 1: Topical application to the face twice daily for 12 weeks. intervention 2: vehicle control applied topically twice daily for 12 weeks

Protocol document: