Conditions: Obesity Insulin Resistance Inflammation
Keywords: 25-hydroxyvitamin D Parathyroid hormone Lean mass Muscular strength Glucose tolerance
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 34
Healthy volunteers: yes

Brief summary:
The study was designed to assess the effects of vitamin D supplementation during exercise training on body composition, muscle function, and glucose tolerance. The investigators hypothesis for these studies is that vitamin D supplementation enhances exercise-induced increases in strength and lean mass, potentially through enhancing insulin sensitivity and reducing inflammation.

Detailed description:
The study was designed to assess the effects of vitamin D supplementation during exercise training on body composition, muscle function, and glucose tolerance. It was a double-blind, randomized, placebo-controlled, clinical trial with participants randomized into either a 4,000 IU/day vitamin D or placebo group and all participants completed 12 wks (3 d/wk) of exercise training.

Arms:
arm 1: Participants in this arm consumed a 4000 IU vitamin D supplement daily for 12 weeks while participating in a resistance exercise training program. arm 2: Participants in this arm consumed a placebo (microcrystalline cellulose) daily for 12 weeks while participating in a resistance exercise training program.

Interventions: intervention 1: Vitamin D intervention 2: Placebo
Intervention descriptions: intervention 1: 4000 IU of vitamin D per day for 12 weeks. intervention 2: Placebo (microcrystalline cellulose) ingestion each day for 12 weeks.

Protocol document: