Conditions: Type 2 Diabetes Mellitus
Keywords: diabetes exenatide once weekly Byetta Amylin Lilly
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 691
Healthy volunteers: no

Brief summary:
Previous studies have suggested that a once-weekly formulation of exenatide may provide sustained glycemic control. These previous studies of exenatide once weekly have been conducted in non-Asian populations, so this study has been developed to support the local regulatory requirements of China, Korea, Japan, India, and Taiwan.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: exenatide once weekly intervention 2: exenatide twice daily
Intervention descriptions: intervention 1: 2.0mg subcutaneous injection, once a week intervention 2: 5mcg subcutaneous injection twice a day (4 weeks), 10mcg subcutaneous injection twice a day (22 weeks)

Protocol document: