Conditions: Non Erosive Reflux Disease Chronic Gastritis
Keywords: GI Nexium Phase IV Co-diagnosed NERD
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 305
Healthy volunteers: no

Brief summary:
To compare the symptom control rate between 8 weeks esomeprazole treatment regimen group and 2 weeks esomeprazole treatment regimen group in co-diagnosed NERD and chronic gastritis patients, as evaluated by GerdQ after 24 weeks maintenance treatment/follow up.

Detailed description:
A multicenter, randomized, open-label Phase IV study exploring symptom control rate in co-diagnosed NERD and chronic gastritis patients treated with 8 weeks esomeprazole treatment regimen and 2 weeks esomeprazole treatment regimen.

Arms:
arm 1: 20 mg q.d. (quaque die) once a day dosing for 8 weeks arm 2: 20 mg q.d. (quaque die) once a day dosing for 2 weeks

Interventions: intervention 1: Esomeprazole intervention 2: Esomeprazole
Intervention descriptions: intervention 1: 20mg Esomeprazole once daily, 8 weeks and 24 weeks on-demand treatment intervention 2: 20mg Esomeprazole once daily, 2 weeks and 24 weeks follow up

Protocol document: