Conditions: Iron Overload Hereditary Hemochromatosis
Keywords: Deferasirox ICL670A Iron chelators Deferiprone Transfusional Hemochromatosis
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 49
Healthy volunteers: no

Brief summary:
Brief Summary: This study was designed to explore a safe dose and characterize the preliminary safety and efficacy of ICL670 in adult patients with previously documented history of homozygous C282Y.

Detailed description:

Arms:
arm 1: Three dose cohorts: 5 mg/kg/day, 10 mg/kg/day, 15 mg/kg/day

Interventions: intervention 1: Deferasirox (ICL670)
Intervention descriptions: intervention 1: None

Protocol document: