Conditions: Anxiety Anxiety Disorders Anxiety Neuroses Anxiety States
Keywords: Generalized anxiety disorders anxiety adjunct treatment in anxiety anxiety disorder partial or non-responder in anxiety
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 409
Healthy volunteers: no

Brief summary:
This study is being carried out to see if extended release quetiapine fumarate (Seroquel®XL) when added to standard selective serotonin reuptake inhibitor (SSRI) / serotonin-norepinephrine reuptake inhibitor (SNRI) therapy is effective and safe for the treatment of Generalized Anxiety Disorder in patients with partial or no response to SSRI/SNRI alone or in combination with a benzodiazepine, and if so, how it compares with placebo

Detailed description:

Arms:
arm 1: Adjunctive Placebo Seroquel XR to anxiety treatment arm 2: Adjunctive Seroquel XR to anxiety treatment

Interventions: intervention 1: Placebo intervention 2: quetiapine fumarate XR
Intervention descriptions: intervention 1: oral intervention 2: oral

Protocol document: