Conditions: Plaque Psoriasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 138
Healthy volunteers: no

Brief summary:
This clinical trial will evaluate the efficacy and safety of Clobex® (clobetasol propionate) Spray 0.05% and Vectical™ (calcitriol) Ointment 3 µg/g over a four week period of use in one of two different regimens:

1. Vectical™ Ointment treatment, twice daily on weekdays (Mon - Fri) and Clobex® Spray treatment twice daily on weekends (Sat - Sun) for 28 days
2. Clobex® Spray once each morning and Vectical™ Ointment once each evening for 28 days

Detailed description:

Arms:
arm 1: Vectical™ Ointment weekdays \& Clobex® Spray weekends regimen arm 2: Clobex® Spray morning and Vectical™ Ointment evening regimen

Interventions: intervention 1: Vectical™ Ointment weekdays and Clobex® Spray weekends regimen intervention 2: Clobex® Spray morning and Vectical™ Ointment evening regimen
Intervention descriptions: intervention 1: Vectical™ Ointment 3 µg/g, topical, apply twice daily on weekdays (Mon-Fri) and Clobex® Spray 0.05% twice daily on weekends (Sat-Sun) for 28 days intervention 2: Clobex® Spray 0.05%, topical, apply once each morning and Vectical™ Ointment 3 µg/g, topical, apply once each evening for 28 days

Protocol document: