Conditions: Smoking Cessation
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 128
Healthy volunteers: no

Brief summary:
Study will determine whether patients with schizophrenia or schizoaffective disorder can be helped to quit smoking safely while using varenicline and receiving smoking cessation counseling.

Detailed description:
This is a safety study.

Arms:
arm 1: Randomization 2:1 treatment to placebo arm 2: None

Interventions: intervention 1: placebo intervention 2: varenicline (CP-526,555)
Intervention descriptions: intervention 1: Randomization 2:1 treatment to placebo intervention 2: One week of titration up to 1mg bid and 11 weeks of dosing at 1mg bid

Protocol document: