Conditions: Systemic Lupus Erythematosus
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 4
Healthy volunteers: no

Brief summary:
Women with Systemic Lupus Erythematosus (SLE) are prone to cardiovascular disease. Early detection of improvement of endothelial function with simvastatin could be a clue for future intervention trials.

Detailed description:

Arms:
arm 1: Arm 1: Drug arm 2: Arm 2: Placebo

Interventions: intervention 1: simvastatin intervention 2: Comparator: Placebo
Intervention descriptions: intervention 1: simvastatin 20mg daily at nights for 12 weeks. Tablets intervention 2: placebo daily at nights for 12 weeks. Tablets

Protocol document: