Conditions: Glioblastoma Astrocytoma Oligodendroglioma Brain Tumor, Recurrent
Keywords: Temozolomide Brain Tumor, Recurrent Chemotherapy
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 25
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy of temozolomide on a protracted schedule, after standard 5-day temozolomide regimen in patients with recurrent or progressive high grade glioma.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: Temozolomide
Intervention descriptions: intervention 1: 100 mg/m2/day, (PO) orally, on days between 1 and 21 of each 28 day cycles. Number of cycles: Until progression or unacceptable toxicity

Protocol document: