Conditions: Schizophrenia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 91
Healthy volunteers: no

Brief summary:
The primary objectives of the study is to confirm if the efficacy of intramuscular injection (IM) olanzapine 10 milligrams (mg) in patients with an exacerbation of schizophrenia with acute psychotic agitation is greater than intramuscular placebo by comparing changes from baseline to 2 hours after the first IM injection of agitation.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Rapid-Acting Intramuscular Olanzapine intervention 2: Placebo
Intervention descriptions: intervention 1: Administered by means of intramuscular injection (IM) with the possibility of second 10 milligram (mg) injection 2 to 4 hours after first injection, for a maximum of 2 injections intervention 2: Administered by means of IM with the possibility of second injection 2 to 4 hours after first injection, for a maximum of 2 injections

Protocol document: