Conditions: Stroke
Keywords: Cerebral Infarction acute ischemic stroke Brain ischemia
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 58
Healthy volunteers: no

Brief summary:
The purpose of this study is to confirm the efficacy and safety of intravenously administered alteplase in patients with acute ischemic stroke based on the rate of recanalization assessed by magnetic resonance angiography (MRA), the rate of patients with a modified Rankin Scale (mRS) score of 0-1, and the incidence of symptomatic intracranial hemorrhage (sICH), in comparison with the data reported in the current literature.

Detailed description:

Arms:
arm 1: 0.6mg/kg intravenous alteplase with 10% being administered as a bolus followed by continuous infusion of the remainder over 1 hour

Interventions: intervention 1: Alteplase
Intervention descriptions: intervention 1: 0.6 mg/kg of Alteplase is intravenously administered

Protocol document: