Conditions: Carcinoma, Non-Small Cell Lung Carcinoma, Small Cell Lung Metastases
Keywords: Zometa bone metastasis lung cancer non-small cell lung cancer small cell lung cancer bone metabolic markers tartrate resistant acid phosphatase
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 28
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate a new blood test as a way to follow the effect of Zometa in treating bone metastases due to lung cancer.

Detailed description:
The purpose of this research study is to evaluate a new blood test as a way to follow the effect of Zometa in treating bone metastases. The blood test will look for a protein, called TRAP, which is released into the blood stream by the breakdown of bone. This study will compare the TRAP blood test with other blood tests for bone destruction.

Arms:
arm 1: 3.0-4.0 mg by IV (in the vein), once a month for 6 months

Interventions: intervention 1: zoledronic acid
Intervention descriptions: intervention 1: 3.0-4.0 mg by IV (in the vein), once a month for 6 months

Protocol document: