Conditions: Acute Ischemic Stroke
Keywords: Stroke Nonhemorrhagic hypothermia
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 30
Healthy volunteers: no

Brief summary:
Caffeinol is a combination of caffeine and alcohol. The amount given is about the same as 1-2 glasses of wine and 3-4 cups of coffee. The patient receives a one time dose given over two hour while being cooled to 34.5 C.

Detailed description:

Arms:

Interventions: intervention 1: Caffeinol intervention 2: hypothermia
Intervention descriptions: intervention 1: Infusion of caffeinol (9mg/kg caffeine + 0.4g/kg ethanol) over 2 hours. intervention 2: External or internal cooling for 24 hours and rewarming over 12 hours.

Protocol document: