Conditions: Type 2 Diabetes Mellitus
Keywords: diabetes exenatide once weekly Byetta liraglutide Victoza Amylin Lilly
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 912
Healthy volunteers: no

Brief summary:
No head to head comparisons between exenatide once weekly and liraglutide have been performed. Therefore, the purpose of this study is to compare exenatide once weekly to once-daily liraglutide with regard to HbA1c, body weight, subject-reported outcomes, and other clinical benefits. The study includes a 26-week treatment period and a safety follow-up visit 10 weeks after the final study drug dose.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: exenatide once weekly intervention 2: liraglutide
Intervention descriptions: intervention 1: subcutaneous injection, 2mg, once weekly intervention 2: subcutaneous injection, forced titration to 1.8mg, once daily

Protocol document: