Conditions: Chronic Sinusitis
Keywords: Nasal Spray Nasal Drop Intranasal Medication
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 18
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine the distribution of nasal sprays and nasal drops when used.

Detailed description:
The purpose of this study is to determine the distribution of nasal sprays and nasal drops when used. The study hypothesizes that nasal drops will reach the frontonasal region more often than nasal sprays.

Arms:
arm 1: This arm of the study will contain subjects who will spray 2-4 sprays of a nasal contrast solution in their nares. Following administration of the spray, the subjects will then have a Xoran mini-CAT scan of their sinuses. arm 2: This arm will contain subjects who will place two drops of a nasal contrast solution in each nose. Following administration of the nasal contrast, the subjects will then have a Xoran miniCAT scan of their sinuses.

Interventions: intervention 1: Sinus CT Scan intervention 2: Omnipaque 240 Contrast Solution intervention 3: Omnipaque 240 mg I/mL
Intervention descriptions: intervention 1: Subjects will undergo a Xoran miniCAT scan of their sinuses intervention 2: Subjects will spray 2-4 drops of half-strength Omnipaque 240 mgI/mL into each nare. Each spray is approximately 0.1 ml. intervention 3: Subjects will place two drops of half-strength Omnipaque 240 mg I/mL intranasally to each nose. Each drop is approximately 1 ml.

Protocol document: