Conditions: Hepatic Encephalopathy
Keywords: Minimal hepatic encephalopathy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 42
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether alteration of gut flora with rifaximin can lead to improvement in driving performance, psychometric test performance, and quality of life in patients with minimal hepatic encephalopathy (MHE) and cirrhosis in a randomized, blinded, placebo-controlled trial.

Detailed description:

Arms:
arm 1: Will be given placebo and follow the exact procedures as the experimental section arm 2: None

Interventions: intervention 1: Rifaximin intervention 2: placebo
Intervention descriptions: intervention 1: 550mg BID rifaximin for 8 weeks intervention 2: same as the experimental arm

Protocol document: