Conditions: Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 808
Healthy volunteers: no

Brief summary:
To evaluate the blood pressure efficacy between losartan and valsartan at equivalent dosage during a 3 months treatment.

Detailed description:

Arms:
arm 1: Drug Arm arm 2: active comparator

Interventions: intervention 1: losartan potassium (+) hydrochlorothiazide intervention 2: Comparator: Valsartan (+) Hydrochlorothiazide
Intervention descriptions: intervention 1: losartan potassium 50 mg/12.5 Hydrochlorothiazide (HCTZ) titrated as needed to losartan potassium 100 mg/25 mg Hydrochlorothiazide intervention 2: Valsartan 80 mg/ Hydrochlorothiazide 12.5 mg/day titrated as needed to valsartan 160 mg/25 mg Hydrochlorothiazide

Protocol document: