Conditions: Type 2 Diabetes Mellitus (T2DM)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1147
Healthy volunteers: no

Brief summary:
This study will examine whether the incidence of hypoglycemia in patients fasting for Ramadan is lower when treated with sitagliptin as compared to sulfonylurea treatment.

Detailed description:
This study and NCT01340768 (MK-0431-262) have the same design but are conducted under separate protocols, in different countries, according to local guidelines.

Arms:
arm 1: Sitagliptin 100 mg administered orally daily as monotherapy or in combination with metformin over the Ramadan period. arm 2: Sulfonylurea administered orally daily as monotherapy or in combination with metformin over the Ramadan period.

Interventions: intervention 1: Sitagliptin phosphate intervention 2: Comparator: Sulfonylurea intervention 3: Metformin
Intervention descriptions: intervention 1: Sitagliptin 100 mg tablet administered orally once daily over the Ramadan period. intervention 2: Sulfonylurea (glibenclamide, glimepiride, or gliclazide) administered orally daily over the Ramadan period as per physician's prescription intervention 3: Participants could continue pre-study metformin as concomitant therapy during the study.

Protocol document: