Conditions: Rhinitis, Allergic, Perennial Allergic Rhinitis
Keywords: fluticasone propionate Vienna Challenge Chamber glucocorticosteroids allergic rhinitis
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 59
Healthy volunteers: no

Brief summary:
This is a single-centre, randomised, double-blind, four-period, incomplete block, crossover study, with 8 days repeat dosing of intranasal Fluticasone Propionate (25, 50, 100, 200ug) and/or placebo in the Vienna Challenge Chamber in subjects with allergic rhinitis.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None

Interventions: intervention 1: Fluticasone propionate intervention 2: Placebo
Intervention descriptions: intervention 1: Corticosteriod, with anti-inflammatory effects intervention 2: Placebo comparator

Protocol document: