Conditions: Diabetes Diabetes Mellitus, Type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 245
Healthy volunteers: no

Brief summary:
This trial is conducted in Africa, Asia and North America. The aim of this trial is to compare two insulin degludec (NN1250, SIBA) formulations with each other and with insulin glargine, all in combination with metformin in insulin naive subjects with type 2 diabetes.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: insulin glargine intervention 2: insulin degludec intervention 3: insulin degludec intervention 4: insulin degludec intervention 5: metformin
Intervention descriptions: intervention 1: Treat-to-target dose titration scheme, s.c. injection. intervention 2: Formulation D: Treat-to-target dose titration scheme, s.c. injection, once daily intervention 3: Formulation E: Treat-to-target dose titration scheme, s.c. injection, once daily intervention 4: Formulation D: Treat-to-target dose titration scheme, s.c. injection, 3 times weekly intervention 5: Tablets, 1500-2000 mg/day

Protocol document: