Conditions: Arthritis, Rheumatoid
Keywords: Arthritis Rheumatoid
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 305
Healthy volunteers: no

Brief summary:
Investigating the safety and tolerability of a p38 inhibitor as monotherapy in subjects who have failed at least 1 DMARD.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None

Interventions: intervention 1: placebo intervention 2: PH-797804 intervention 3: PH-797804 intervention 4: PH-797804 intervention 5: PH-797804
Intervention descriptions: intervention 1: Capsule, once daily (QD) for 12 weeks intervention 2: Capsule, 0.5 mg of PH-797804, once daily (QD) for 12 weeks intervention 3: Capsule, 3 mg of PH-797804, once daily (QD) for 12 weeks intervention 4: Capsule, 6 mg of PH-797804, once daily (QD) for 12 weeks intervention 5: Capsule, 10 mg of PH-797804, once daily (QD) for 12 weeks

Protocol document: