Conditions: Cough
Keywords: Hyper-responsiveness, reflux cough
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 5
Healthy volunteers: no

Brief summary:
The study aim is to determine the effect of 8 weeks of anti-reflux treatment (full acid suppression) on bronchial hyper-responsiveness and whether there is a symptomatic improvement.

Detailed description:

Arms:
arm 1: 20 mg oralomeprazole oral tablet twice daily and ranitidine 300 mg oral tablet once daily nocte

Interventions: intervention 1: Omeprazole intervention 2: Ranitidine
Intervention descriptions: intervention 1: 20 mg BD tablet 8 weeks duration intervention 2: 300 mg od nocte tablet 8weeks duration

Protocol document: