Conditions: Post Operative Pain
Keywords: pain morphine hydromorphone nausea vomiting pruritis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: no

Brief summary:
Both morphine and hydromorphone are pain medications commonly used after surgery. It is thought at the institution that hydromorphone causes less side effects but this has not been studied. The study proposes to treat the patients with either morphine or hydromorphone and determine how much nausea, vomiting, and itching they have with each drug

Detailed description:

Arms:
arm 1: Patients receive morphine 1mg/dose PCA for postsurgical pain; max 10 mg/hr; lockout 6 minutes. arm 2: Patients receive hydromorphone 0.2mg/dose PCA for postsurgical pain; max 10mg/hr; lockout 6 minutes.

Interventions: intervention 1: Morphine PCA intervention 2: Hydromorphone PCA
Intervention descriptions: intervention 1: Morphine 1mg/mL, dose 1mL, lockout 6 minutes, max 10mL intervention 2: hydromorphone PCA 0.2mg/lml, dose 1ml, lockout 6min, max 10ml

Protocol document: