Conditions: Osteoarthritis
Keywords: Osteoarthritis, oral salmon calcitonin, treatment, efficacy, tolerability
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1176
Healthy volunteers: no

Brief summary:
The purpose of this Phase III study is to evaluate the efficacy and safety of oral salmon calcitonin in the treatment of patients with osteoarthritis of the knee.

Detailed description:

Arms:
arm 1: SMC021 Oral Calcitonin, 0.8 mg twice daily during 24 months arm 2: SMC021 Placebo, orally twice daily during 24 months

Interventions: intervention 1: SMC021 Oral Calcitonin intervention 2: SMC021 Placebo
Intervention descriptions: intervention 1: 0.8mg SMC021 (Oral Calcitoinin) twice daily intervention 2: Placebo orally, twice daily

Protocol document: