Conditions: Corneal Neovascularization
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the effectiveness and safety of Topical Bevacizumab (Avastin) for treatment of corneal neovascularization.

Detailed description:
Primary outcomes measures included neovascular area (NA), defined as the area of the corneal vessels themselves; vessel caliber (VC), defined as the mean diameter of the corneal vessels; and invasion area (IA), defined as the fraction of the total cornea into which the vessels extend. The occurrence of ocular and systemic adverse events was closely monitored throughout the course of the study.

Arms:
arm 1: Each patient will receive topical Avastin in one eye.

Interventions: intervention 1: Topical Avastin 1%
Intervention descriptions: intervention 1: Avastin (bevacizumab) 1%

Protocol document: