Conditions: Migraine Disorders
Keywords: Combination product, sumatriptan succinate, naproxen sodium, absorption, pharmacokinetics, disintegration, gastric transit, gastric scintigraphy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 20
Healthy volunteers: no

Brief summary:
An evaluation of tablet disintegration and absorption and gastric transit of sumatriptan and naproxen sodium from a TREXIMA tablet and eletriptan from a RELPAX 40mg tablet.

Detailed description:

Arms:
arm 1: open-label active drug arm 2: open-label active drug

Interventions: intervention 1: Combination Product (sumatriptan succinate / naproxen sodium) intervention 2: RELPAX(eletriptan) 40mg Tablet
Intervention descriptions: intervention 1: sumatriptan/naproxen sodium intervention 2: eletriptan tablets

Protocol document: