Conditions: Dry Eye
Enrollment: 332

Brief summary:
To investigate that the efficacy of 3% DE-089 ophthalmic solution (one drop at a time, 6 times daily, 4 weeks topical administration), in comparison to 0.1% sodium hyaluronate ophthalmic solution (0.1% HA) (one drop at a time, 6 times daily, 4 weeks topical administration), is at least non-inferior in the change in fluorescein staining score, and is superior in the change in Rose bengal score, in a multicenter, double-masked, parallel-group comparison study. Safety profile will likewise be compared.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: 3% DE-089 ophthalmic solution intervention 2: 0.1% sodium hyaluronate ophthalmic solution
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: