Conditions: Pain, Postoperative
Keywords: thyroidectomy pain, postoperative pregabalin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 99
Healthy volunteers: no

Brief summary:
The investigators hypothesize that pregabalin will decrease post-operative pain scores and analgesic use following robot-assisted endoscopic thyroidectomy compared to placebo. The primary outcome will be acute postoperative pain, measured by a verbal numerical rating score (VNRS) and total analgesic consumption during postoperative 48 hours. The secondary outcome will be the incidence of chronic pain and hypoesthesia in the anterior chest at 3 months after operation.

Detailed description:

Arms:
arm 1: Patients receive oral Placebo 150 mg 1 hour prior to surgery, and 12 hours later arm 2: Patients receive oral pregabalin 150 mg 1 hour prior to surgery, and 12 hours later

Interventions: intervention 1: Pregabalin intervention 2: Vitamin Complex (placebo)
Intervention descriptions: intervention 1: Pregabalin 150 mg orally intervention 2: Vitamin Complex 150 mg orally

Protocol document: