Conditions: Breast Neoplasms Neoplasm Metastasis
Keywords: Advanced Breast Cancer
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 75
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine if SKI-606 (Bosutinib) is effective in the treatment of advanced or metastatic breast cancer. Patients must have current Stage IIIB, IIIC or IV breast cancer and have progressed after 1 to 3 prior chemotherapy regimens.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: SKI-606 (Bosutinib)
Intervention descriptions: intervention 1: SKI-606 (Bosutinib) 400mg once daily, for as long as tolerated or until disease progression.

Protocol document: