Conditions: Psoriasis
Keywords: Psoriasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 176
Healthy volunteers: no

Brief summary:
Eligible subjects will be randomly assigned to one of three dose regimens of oral R115866 or placebo for the treatment of severe plaque psoriasis for 12 twelve weeks. The safety and efficacy of R115866 will be evaluated during the treatment period and the 8-week post treatment follow-up period.

Detailed description:

Arms:
arm 1: Talarozole 0.5 mg arm 2: Talarozole 1.0 mg arm 3: Talarozole 2.0 mg arm 4: Talarozole matching Placebo

Interventions: intervention 1: Talarozole
Intervention descriptions: intervention 1: Oral Capsule Once Daily

Protocol document: