Conditions: HIV Infections
Keywords: HIV Infections
Allocation: NON_RANDOMIZED | Intervention model: 
Enrollment: 1047
Healthy volunteers: no

Brief summary:
To provide access to maraviroc to patients who have limited or no therapeutic treatment options and to collect more safety data in a broader patient population.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: maraviroc
Intervention descriptions: intervention 1: The nominal dose for maraviroc is 300 mg twice a day (BID). However, the dosage of maraviroc should be adjusted based on optimal background therapy (OBT) patient is taking. If OBT includes CYP3A4 inhibitor (with or without inducers) maraviroc dose should be 150 mg BID and if OBT includes CYP3A4 inducer (without inhibitors) maraviroc dose should be 600mg BID. If OBT does not include any CYP3A4 inducers or inhibitors maraviroc dose should be 300 mg BID.

Protocol document: