Conditions: Parkinson's Disease
Keywords: Parkinson's Disease motor complications dyskinesia Motor complications associated with Parkinson's
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 27
Healthy volunteers: no

Brief summary:
The purpose of this study is to obtain preliminary information on the effect of piclozotan on motor complications associated with Parkinson's Disease.

Detailed description:

Arms:
arm 1: Participants will be randomized to receive two 12-hour intravenous (IV) infusions of piclozotan administered at a plasma level of 30 ng/mL over 2 inpatient days. arm 2: Participants will be randomized to receive two 12-hour intravenous (IV) infusions of 0.9 % sodium chloride (normal saline) administered at a plasma level of 30 ng/mL over 2 inpatient days.

Interventions: intervention 1: piclozotan intervention 2: 0.9% sodium chloride (normal saline)
Intervention descriptions: intervention 1: piclozotan, intravenous (IV) infusion intervention 2: 0.9% sodium chloride (normal saline) intravenous (IV) infusion

Protocol document: