Conditions: Acne
Keywords: Acne Vulgaris Acne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 54
Healthy volunteers: no

Brief summary:
The purpose of the study is to determine the development of microbial resistance when using one of two topical acne therapies for the treatment of facial acne vulgaris.

Detailed description:
To investigate the development of microbial resistance when using one of two topical acne therapies for the treatment of moderate to moderately severe facial acne vulgaris. Clinical efficacy and tolerability will be assessed.

Arms:
arm 1: Clindamycin and benzoyl peroxide gel arm 2: Clindamycin and tretinoin gel

Interventions: intervention 1: Duac intervention 2: Ziana gel
Intervention descriptions: intervention 1: Clindamycon and benzoyl peroxide topical gel once a day for 12 weeks intervention 2: Clindamycin and tretinoin gel once a day for 12 weeks.

Protocol document: