Conditions: Seasonal Allergic Rhinitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 1577
Healthy volunteers: no

Brief summary:
This study will evaluate the ability of montelukast to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine and placebo.

Detailed description:

Arms:
arm 1: montelukast arm 2: loratadine arm 3: placebo arm 4: montelukast/loratadine

Interventions: intervention 1: Comparator: montelukast intervention 2: Comparator: loratadine intervention 3: Comparator: placebo intervention 4: Comparator: montelukast/loratadine
Intervention descriptions: intervention 1: 10 mg montelukast tablet given once daily at bedtime for 2 weeks intervention 2: 10 mg loratadine tablet given once daily at bedtime for 2 weeks intervention 3: placebo tablet given once daily at bedtime for 2 weeks intervention 4: montelukast 10-mg/loratadine 10-mg combination tablet taken orally once daily at bedtime for 2 weeks

Protocol document: