Conditions: Posterior Blepharitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 75
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the effectiveness and safety of Topical Interleukin-1-Receptor Antagonist in treatment of signs and symptoms of posterior blepharitis.

Detailed description:

Arms:
arm 1: 2.5% IL-1Ra arm 2: Artificial Tear arm 3: 5% IL-1Ra

Interventions: intervention 1: 2.5% IL-1Ra intervention 2: Placebo intervention 3: 5% IL-1Ra
Intervention descriptions: intervention 1: 2.5% custom made topical IL-1Ra three times a day in both eyes for three months intervention 2: custom eye drop to be applied three times a day in both eyes for three months intervention 3: 5% custom made topical IL-1Ra to both eyes 3 times a day for 3 months

Protocol document: