Conditions: Chronic Kidney Disease End Stage Renal Disease Coronary Artery Calcification Vascular Calcification Calcification Cardiovascular Disease Chronic Renal Failure Hyperparathyroidism Kidney Disease Nephrology Secondary Hyperparathyroidism
Keywords: calcification vascular calcification coronary vascular calcification chronic kidney disease end stage renal disease dialysis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 360
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate whether cinacalcet + low dose vitamin D attenuates the progression of vascular calcification over one year, compared with a treatment regimen that includes flexible vitamin D dosing in the absence of cinacalcet, in subjects with chronic kidney disease receiving hemodialysis

Detailed description:

Arms:
arm 1: Standard of care, without use of cinacalcet.

Interventions: intervention 1: cinacalcet
Intervention descriptions: intervention 1: Low dose vitamin D with cinacalcet

Protocol document: