Conditions: Epilepsy
Keywords: Keppra XR conversion to monotherapy partial seizures
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 228
Healthy volunteers: no

Brief summary:
The primary objective of this study is to assess the efficacy of two doses of Keppra XR compared with a historical control as the placebo, in the monotherapy treatment of partial onset seizures.

Detailed description:

Arms:
arm 1: 1000 mg/day once daily for 18 weeks (administered as two levetiracetam XR tablets and two placebo tablets once daily) arm 2: 2000 mg/day once daily for 18 weeks (administered as four levetiracetam XR tablets once daily)

Interventions: intervention 1: Keppra XR intervention 2: Keppra XR
Intervention descriptions: intervention 1: Administered as two 500 mg tablets (1000 mg) and two placebo tablets once daily for 18 weeks intervention 2: Administered as four 500 mg tablets (2000 mg) once daily for 18 weeks

Protocol document: