Conditions: Obesity
Keywords: obesity overweight magnetic resonance imaging naltrexone bupropion
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 46
Healthy volunteers: no

Brief summary:
The purpose of this study was to assess the effect of naltrexone SR/bupropion SR (NB) on brain function in response to food cues using functional magnetic resonance imaging in overweight or obese subjects.

Detailed description:

Arms:
arm 1: Naltrexone SR 32 mg/bupropion SR 360 mg/day arm 2: Placebo tablets

Interventions: intervention 1: Naltrexone SR 32 mg/bupropion SR 360 mg/day intervention 2: Placebo intervention 3: fMRI scan
Intervention descriptions: intervention 1: None intervention 2: None intervention 3: fMRI to assess the effects of the drug/placebo on areas of the brain

Protocol document: