Conditions: Breast Cancer
Keywords: Breast Cancer Breast Neoplasms Tumors or cancer of the human BREAST Tumor or cancer of the human MAMMARY GLAND
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 197
Healthy volunteers: no

Brief summary:
The purpose of this multi-centre, randomised, double-blind, parallel-group study is to compare efficacy and safety between anastrozole and tamoxifen in pre- and post-operative administration under goserelin acetate treatment for premenopausal breast cancer patients

Detailed description:

Arms:
arm 1: Tamoxifen arm 2: Anastrazole (Arimidex)

Interventions: intervention 1: Tamoxifen intervention 2: Anastrazole (Arimidex) intervention 3: Goserelin acetate (Zoladex)
Intervention descriptions: intervention 1: 20 mg once daily oral dose intervention 2: 1 mg once daily oral dose intervention 3: 3.6mg/month depot injection

Protocol document: