Conditions: PCOS
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 2
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine whether 6 months of fiber supplementation will improve ovulation in women with polycystic ovary syndrome (PCOS).

Detailed description:
We hypothesize that 6 months of fiber supplementation will improve ovulation in women with PCOS by improving insulin sensitivity independent of weight loss. In this pilot study, we will determine the feasibility of conducting a larger double-blind, randomized trial in women with PCOS to test this hypothesis. We will evaluate 15 women over a 10-month period, starting with a 4-month intervention-free observation period to determine the effect on ovulation of adding up to 22g/day of fiber supplementation to their usual weight-maintenance diets (to achieve 28-36 g fiber/day assuming baseline dietary fiber intake, could feasibly be translated into clinical practice.

Arms:
arm 1: 2 tablespoons daily

Interventions: intervention 1: Fiber-Stat
Intervention descriptions: intervention 1: Liquid fiber supplement, 2 tablespoons twice daily.

Protocol document: