Conditions: ADHD
Keywords: cigarette smoking ADHD adolescents Concerta
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 203
Healthy volunteers: no

Brief summary:
This study will consist of a six-week open-label treatment period with an extended duration methylphenidate (OROS MPH) followed by subsequent monthly visits for 24 months in a large sample of youths aged 12-17 who meet Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for ADHD.

The researchers hypothesize that OROS MPH treatment will be associated with low rates of cigarette smoking in ADHD youth.

Detailed description:

Arms:
arm 1: Single arm- open treatment with extended duration methylphenidate (OROS MPH)

Interventions: intervention 1: methylphenidate HCl (Concerta)
Intervention descriptions: intervention 1: OROS MPH will be openly prescribed to a maximum of 1.5 mg/kg/day (maximum 126 mg/day). Doses will be titrated according to clinical assessment of efficacy and tolerability.

Protocol document: