Conditions: Hypercholesterolemia
Keywords: Hypercholesterolemia Statins Ezetimibe
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 34
Healthy volunteers: yes

Brief summary:
The purpose of this study is to compare the efficacy of a Vytorin 10/80 tablet, an approved agent for the treatment of elevated LDL cholesterol which combines the cholesterol absorption inhibitor Ezetimibe 10 mg and simvastatin 80 mg, when split into 4 using a tablet splitter, versus a whole simvastatin 20 milligram tablet.

Detailed description:

Arms:
arm 1: Vytorin 10/80 divided into 4 arm 2: Simvastatin 20 milligrams

Interventions: intervention 1: Vytorin intervention 2: Simvastatin
Intervention descriptions: intervention 1: Vytorin 10/80 split into 4 intervention 2: Simvastatin 20 milligrams

Protocol document: