Conditions: Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 2500
Healthy volunteers: no

Brief summary:
To determine the effectiveness of four different strength combinations of three approved anti-hypertension therapies (olmesartan medoxomil, amlodipine, and hydrochlorothiazide) for lowering blood pressure.

Detailed description:

Arms:
arm 1: olmesartan medoxomil 40mg and amlodipine 10mg arm 2: olmesartan medoxomil 40mg and hydrochlorothiazide 25mg arm 3: amlodipine 10mg and hydrochlorothiazide 25mg arm 4: olmesartan medoxomil 40mg, amlodipine 10mg, and hydrochlorothiazide 25mg

Interventions: intervention 1: Olmesartan medoxomil intervention 2: Amlodipine intervention 3: Hydrochlorothiazide
Intervention descriptions: intervention 1: 40mg olmesartan medoxomil intervention 2: Amlodipine 10mg intervention 3: Hydrochlorothiazide 25mg

Protocol document: