Conditions: Anesthesia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 149
Healthy volunteers: no

Brief summary:
The primary purpose of this study is to determine the dose requirements of rocuronium bromide when administered as a bolus dose (a single, large dose) for intubation (insertion of a tube through the nose or mouth into the trachea to provide artificial ventilation) and when administered by either continuous infusion or bolus doses for maintenance of muscle relaxation in term neonates (birth to \<28 days old), infants (28 days to \<=3 months) and toddlers (\>3 months to \<=2 years), children (2 years to less than or equal to 11 years of age), and adolescents (\>11 years to less than or equal to 17 years of age).

Detailed description:

Arms:
arm 1: Rocuronium bolus maintenance arm 2: Rocuronium continuous infusion maintenance

Interventions: intervention 1: Rocuronium bolus maintenance intervention 2: rocuronium continuous infusion maintenance
Intervention descriptions: intervention 1: Subjects received a bolus dose of rocuronium for intubation followed by bolus doses for maintenance of muscle relaxation intervention 2: Subjects received a bolus dose of rocuronium for intubation followed by continuous infusion of rocuronium for maintenance of muscle relaxation

Protocol document: