Conditions: Fibromyalgia
Keywords: Fibromyalgia; fMRI; pain; pregabalin; Lyrica; imaging
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 27
Healthy volunteers: no

Brief summary:
The purpose of this study is to explore how pregabalin works in patients with fibromyalgia by evaluating brain imaging signals. To find out whether fMRI (functional magnetic resonance imaging) is an efficient way to show whether new pain medications are effective in treating fibromyalgia.

Detailed description:
Methodology study

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Pregabalin, then placebo intervention 2: Placebo, then pregabalin
Intervention descriptions: intervention 1: Placebo and pregabalin will be given orally twice daily in capsules at different times during the course of the study. The highest dose of pregabalin to be used in the study is 450 mg/day. intervention 2: Placebo and pregabalin will be given orally twice daily in capsules at different times during the course of the study. The highest dose of pregabalin to be used in the study is 450 mg/day.

Protocol document: