Conditions: Hepatitis B Chronic Disease
Keywords: chronic hepatitis B infection
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 69
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate antiviral activity and efficacy of entecavir (ETV) compared to adefovir in adults with chronic hepatitis B who have not been treated yet with an antiviral medicine.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: entecavir intervention 2: adefovir
Intervention descriptions: intervention 1: Tablets, Oral, ETV 0.5 mg, once daily, up to 96 weeks intervention 2: Tablets, Oral, ADV 10 mg, once daily, up to 96 weeks

Protocol document: