Conditions: Skin Structure Infections Bacterial Skin Diseases Staphylococcal Skin Infections
Keywords: complicated skin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 150
Healthy volunteers: no

Brief summary:
The purpose of this study is to assess the efficacy, safety and tolerability of RX-3341 (delafloxacin), a fluoroquinolone, versus tigecycline, a glycylcycline antibacterial drug, in the treatment of complicated skin and skin structure infections.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: delafloxacin intervention 2: delafloxacin intervention 3: tigecycline
Intervention descriptions: intervention 1: 300 mg intravenous every 12 hours intervention 2: 450 mg intravenous every 12 hours intervention 3: 100 mg then 50 mg intravenous tigecycline every 12 hours

Protocol document: