Conditions: Esophageal Cancer
Keywords: Esophageal cancer
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 3
Healthy volunteers: no

Brief summary:
To determine whether sorafenib is able to change pre-cancerous cells in a way that we believe is important in the progression of cancer.

Detailed description:
To characterize the effects of sorafenib on specific molecular markers in patients with Barrett's esophagus and high grade intraepithelial neoplasia (HGIN) or carcinoma in situ (CIS).

Arms:
arm 1: sorafenib 2 tablets by mouth

Interventions: intervention 1: sorafenib
Intervention descriptions: intervention 1: 2 tablets with water by mouth twice a day for two weeks.

Protocol document: