Conditions: Alzheimer's Disease
Keywords: Alzheimer's disease PF-04447943 efficacy safety plasma concentrations
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 191
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effects of PF-04447943 compared to placebo on cognitive, behavioral and overall symptoms of Alzheimer's disease; evaluate the safety and tolerability of PF-0444793 compared to placebo; and determine the levels of PF-04447943 in the plasma over the course of the study.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: PF-04447943 intervention 2: Placebo
Intervention descriptions: intervention 1: tablets, 25 mg every 12 hours for 12 wks intervention 2: matching placebo tablets, every 12 hours for 12 wks

Protocol document: