Conditions: Rheumatoid Arthritis
Keywords: active disease despite concomitant methotrexate
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
Using repeated arthroscopic biopsies of patients with rheumatoid arthritis, the researchers will assess changes in the immune response that occur as a result of treatment with rituximab.

Detailed description:
Using repeated arthroscopic biopsies of patients with rheumatoid arthritis, the researchers will assess changes in the immune response that occur after treatment with rituximab.

Arms:
arm 1: all patients get treatment

Interventions: intervention 1: rituximab
Intervention descriptions: intervention 1: treatment with rituximab

Protocol document: