Conditions: Tourette Syndrome
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 63
Healthy volunteers: no

Brief summary:
A randomized, double-blind, placebo-controlled, flexible dose study to evaluate efficacy and safety of Pramipexole versus placebo for 6 weeks in children (age 6-17) diagnosed with Tourette Disorder according to DSM IV criteria. The primary efficacy measure will be the Total Tic Score (TTS) of the Yale Global Tic Severity Scale (YGTSS) at 6 weeks.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: pramipexole immediate release (IR) intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: