Conditions: Low Back Pain
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 14
Healthy volunteers: no

Brief summary:
Duloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its pain-relieving properties are not known. We will use functional magnetic resonance imaging (FMRI) to investigate the neural and functional correlates of pain.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: duloxetine intervention 2: Placebo
Intervention descriptions: intervention 1: 30-60mg of duloxetine daily intervention 2: Placebo pill once daily

Protocol document: