Conditions: Healthy
Keywords: Postmenopausal females Volunteers
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 60
Healthy volunteers: yes

Brief summary:
The purpose of this study is to determine if a single dose of LY2541546 has any side effects on the body and to determine how long and how much LY2541546 stays in the bloodstream of the body.

Detailed description:

Arms:
arm 1: Single dose of 7.5 mg LY2541546 administered intravenously (IV) arm 2: Single dose of 25 mg LY2541546 administered IV arm 3: Single dose of 75 mg LY2541546 administered IV arm 4: Single dose of 225 mg LY2541546 administered IV arm 5: Single dose of 750 mg LY2541546 administered IV arm 6: Single dose of 150 mg LY2541546 administered subcutaneous (SC) arm 7: Single dose of placebo administered IV or SC arm 8: Single dose of 225 mg LY2541546 administered IV, open label (OL) arm 9: Single dose of 750 mg LY2541546 administered IV, OL

Interventions: intervention 1: LY2541546 - IV intervention 2: LY2541546 - SC intervention 3: Placebo
Intervention descriptions: intervention 1: Administered IV intervention 2: Administered SC intervention 3: Administered IV or SC

Protocol document: