Conditions: Postoperative Pain Hysterectomy
Keywords: Pain Gynecologic IV Acetaminophen Postoperative Analgesic
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 331
Healthy volunteers: no

Brief summary:
This study will be investigating the efficacy and safety administration of multiple doses of intravenous (IV) acetaminophen (IVAPAP) in the 48 hour period following Gynecologic Surgery.

Detailed description:
The research hypothesis is that IV Acetaminophen will provide greater reduction in pain intensity and greater pain relief for moderate and severe pain as compared to placebo in the 48 hours following surgery.

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: IV Acetaminophen intervention 2: IV Placebo 100 mL solution
Intervention descriptions: intervention 1: Intravenous acetaminophen 1 g/100 mL intervention 2: IV Placebo 100 mL solution dosed at same frequency as IV Acetaminophen every 6 hours (q6h)

Protocol document: