Conditions: Epilepsy, Partial
Keywords: epilepsy lamotrigine Lamictal monotherapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 226
Healthy volunteers: no

Brief summary:
This study is being conducted to determine the effectiveness of a lower monotherapy dose of lamotrigine than that currently approved.

Detailed description:
The study consists of a Treatment phase, where efficacy is determined and a Continuation phase for extended safety information. The Continuation phase is open to all Treatment phase participants and those who did not qualify for treatment because of an insufficient number of seizures during the Baseline phase.

Arms:
arm 1: 300 mg/day treatment arm 2: 250 mg/day treatment

Interventions: intervention 1: lamotrigine, 300 mg/day intervention 2: lamotrigine, 250 mg/day
Intervention descriptions: intervention 1: 300 mg/day intervention 2: 250 mg/day

Protocol document: