Conditions: Obesity Fungal Infection
Keywords: Echinocandin Obesity Pharmacokinetics Pharmacodynamics Fungal infection
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 18
Healthy volunteers: yes

Brief summary:
This study will find how weight affects the dosing of a drug called caspofungin. Currently, the amount of caspofungin a patient receives is the same regardless of the patient's weight.

Detailed description:

Arms:
arm 1: Six volunteers will have a body mass index (BMI) less than 25 kg/m2, 6 will have a BMI 25-40 kg/m2, and 6 will have a BMI greater than 40 kg/m2.

Interventions: intervention 1: Caspofungin
Intervention descriptions: intervention 1: Caspofungin 70mg IV (each volunteer will only receive one dose of the study drug)

Protocol document: