Conditions: Hypercholesterolemia
Allocation: RANDOMIZED | Intervention model: FACTORIAL
Enrollment: 334
Healthy volunteers: no

Brief summary:
The purpose of this study is to test the safety and effectiveness of MK-6213 as compared to MK-6213/Atorvastatin in participants 18 to 75 years) with high cholesterol.

Detailed description:

Arms:
arm 1: 1 MK-6213 160-mg tablet co-administered orally with 1 Atorvastatin 20-mg tablet once daily for 4 weeks arm 2: 1 Atorvastatin 20-mg tablet co-administered orally with 1 tablet of placebo for MK-6312 once daily for 4 weeks arm 3: 1 MK-6213 160-mg tablet co-administered orally with 1 tablet of placebo for Atorvastatin 20-mg once daily for 4 weeks arm 4: 1 tablet of placebo for MK-6213 160 mg co-administered orally with 1 tablet of placebo for Atorvastatin 20-mg tablet once daily for 4 weeks

Interventions: intervention 1: MK-6213 intervention 2: Atorvastatin calcium intervention 3: Placebo for MK-6312 160 mg intervention 4: Placebo for Atorvastatin 20 mg
Intervention descriptions: intervention 1: MK-6213 160 mg for 4 weeks. intervention 2: atorvastatin calcium 20mg for 4 weeks. intervention 3: None intervention 4: None

Protocol document: