Conditions: Rhinitis, Allergic, Seasonal
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 313
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the efficacy and safety of mometasone furoate (SCH 32088) aqueous nasal spray 200 mcg once daily compared to placebo once daily in the treatment of participants with seasonal allergic rhinitis. Flonase (fluticasone propionate) nasal spray 200 mcg once daily has been chosen as the active control for this study.

Detailed description:

Arms:
arm 1: Participants receive 200 mcg of mometasone furoate nasal spray and fluticasone propionate placebo matching nasal spray once daily. arm 2: Participants receive 200 mcg of fluticasone propionate nasal spray and mometasone furoate placebo matching nasal spray once daily. arm 3: Participants receive mometasone furoate placebo matching nasal spray and fluticasone propionate placebo matching nasal spray once daily.

Interventions: intervention 1: Mometasone furoate intervention 2: Fluticasone propionate intervention 3: Mometasone furoate placebo intervention 4: Fluticasone propionate placebo
Intervention descriptions: intervention 1: Mometasone furoate nasal spray, 200 mg once daily intervention 2: Fluticasone propionate nasal spray, 200 mg once daily intervention 3: Mometasone furoate placebo matching nasal spray, once daily intervention 4: Fluticasone propionate placebo matching nasal spray, once daily

Protocol document: