Conditions: Asthma
Keywords: mild asthma allergen challenge early asthmatic response
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 52
Healthy volunteers: no

Brief summary:
We propose to use an inhaled allergen challenge model to explore the individual contributions of the components of a novel long-acting beta agonist (LABA)/ inhaled corticosteroid (ICS) combination product on protection from allergic triggers in asthma.

Detailed description:

Arms:
arm 1: Placebo Inhaler arm 2: ICS/LABA inhaler arm 3: ICS inhaler

Interventions: intervention 1: Fluticasone Furoate intervention 2: FF/Vilanterol (VI; GW642444M) intervention 3: Placebo
Intervention descriptions: intervention 1: FF intervention 2: FF/VI intervention 3: Placebo Inhaler

Protocol document: