Conditions: Anemia Chronic Kidney Disease
Keywords: Anemia
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 7
Healthy volunteers: no

Brief summary:
This study will define an effective starting dose for subcutaneous administration of MK2578 to correct anemia in erythropoiesis-stimulating agent (ESA)-naive patients with chronic kidney disease (CKD) who are not on dialysis while evaluating its safety.

Detailed description:

Arms:
arm 1: MK2578 arm 2: MK2578 arm 3: MK2578 arm 4: darbepoetin alfa

Interventions: intervention 1: MK2578 intervention 2: MK2578 intervention 3: MK2578 intervention 4: Comparator: darbepoetin alfa
Intervention descriptions: intervention 1: MK2578 1.0 mcg/kg/month intervention 2: MK2578 2.0 mcg/kg/month intervention 3: MK2578 3.6 mcg/kg/month intervention 4: darbepoetin alfa

Protocol document: