Conditions: Dry Eye Syndromes
Keywords: Dry eye
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 285
Healthy volunteers: no

Brief summary:
The purpose of the study is to evaluate dose-response, efficacy and safety of CP-690,550 eye drops in patients with dry eye disease.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None arm 5: None

Interventions: intervention 1: CP-690,550 Eye drops intervention 2: CP-690,550 Eye drops intervention 3: CP-690,550 Eye drops intervention 4: CP-690,550 Eye drops-vehicle intervention 5: Sodium Hyaluronate
Intervention descriptions: intervention 1: Ophthalmic topical solution, low dose, dosed once/day, 8 weeks intervention 2: Ophthalmic topical solution, medium dose, dosed once/day, 8 weeks intervention 3: Ophthalmic topical solution, high dose, dosed once/day, 8 weeks intervention 4: Ophthalmic topical solution, vehicle, dosed once/day, 8 weeks intervention 5: Ophthalmic topical solution, dosed 6 times/day, 8 weeks

Protocol document: