Conditions: Type 2 Diabetes Mellitus
Keywords: diabetes exenatide metformin thiazolidinedione Byetta Amylin Lilly
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 165
Healthy volunteers: no

Brief summary:
This study will assess safety and efficacy of exenatide in combination with a thiazolidinedione (TZD) and a TZD plus metformin over 26 weeks in adult patients with type 2 diabetes who have not achieved adequate glycemic control.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: exenatide intervention 2: placebo
Intervention descriptions: intervention 1: subcutaneous injection, 5 mcg or 10 mcg, twice a day (BID) intervention 2: subcutaneous injection, volume equivalent to 5 mcg or 10 mcg of active drug, twice a day

Protocol document: