Conditions: Overactive Bladder
Keywords: Treatment of overactive bladder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 2417
Healthy volunteers: no

Brief summary:
To evaluate the efficacy and safety of fesoterodine in comparison to tolterodine and placebo for overactive bladder

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Tolterodine ER intervention 2: Placebo intervention 3: Fesoterodine
Intervention descriptions: intervention 1: The tolterodine treatment will be 4 mg once daily(QD) for 12 weeks. intervention 2: Placebo treatment will be once daily(QD) for 12 weeks. intervention 3: The fesoterodine treatment will start with 4 mg once daily(QD) for 1 week followed by a forced dose-escalation to 8mg once daily(QD) for 11 weeks.

Protocol document: