Conditions: Osteoarthritis
Keywords: OA Elderly Pain OA of the hips and/or knees
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 219
Healthy volunteers: no

Brief summary:
The primary objective is to compare buprenorphine transdermal delivery system (BTDS) with standard- treatment in subjects with osteoarthritis (OA).

Detailed description:

Arms:
arm 1: Buprenorphine transdermal 7 day analgesic patch arm 2: codeine paracetamol combination tablets

Interventions: intervention 1: Buprenorphine intervention 2: Codeine paracetamol
Intervention descriptions: intervention 1: buprenorphine transdermal system 5, 10 and 20 mg intervention 2: combination tablet of codeine and paracetamol taken orally 3 or 4 times daily. Dosage form ranges from 8/500, 15/500 and 30/500

Protocol document: