Conditions: Non-Constipation Irritable Bowel Syndrome
Keywords: Diarrhea Rifaximin IBS Abdominal pain Bloating
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 637
Healthy volunteers: no

Brief summary:
To evaluate the efficacy of a 14-day course of rifaximin given 3 times a day vs. placebo in providing adequate relief of IBS symptoms.

Detailed description:

Arms:
arm 1: Subjects received placebo tablets 3 times daily for 2 weeks and were followed for 10 weeks after completion of the treatment period. arm 2: Subjects received rifaximin 550 mg tablets 3 times daily for 2 weeks and were followed for 10 weeks after completion of the treatment period.

Interventions: intervention 1: Rifaximin intervention 2: Placebo
Intervention descriptions: intervention 1: None intervention 2: None

Protocol document: