Conditions: Dry Eye Syndrome
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 47
Healthy volunteers: no

Brief summary:
The safety and tolerability of two new artificial tears will be compared to a currently-available artificial tear in subjects with dry eye. Each subject will receive all three products in a randomly assigned order. The subject will use one product at a time for a duration of one week before switching to the next assigned product.

Detailed description:

Arms:
arm 1: Formulation 1: Carboxymethylcellulose Sodium, Glycerin and Polysorbate 80, based artificial tear arm 2: Formulation 2: Carboxymethylcellulose Sodium, Glycerin and Polysorbate 80, based artificial tear arm 3: Glycerin and Polysorbate 80 based artificial tear

Interventions: intervention 1: Formulation 1: Carboxymethylcellulose Sodium, Glycerin and Polysorbate 80, based artificial tear intervention 2: Formulation 2: Carboxymethylcellulose Sodium, Glycerin and Polysorbate 80, based artificial tear intervention 3: Glycerin and Polysorbate 80 based artificial tear
Intervention descriptions: intervention 1: 1 to 2 drops into each eye three times per day intervention 2: 1 to 2 drops into each eye three times per day intervention 3: 1 to 2 drops into each eye three times per day

Protocol document: