Conditions: Major Depressive Disorder
Keywords: Depression Pharmacotherapy Duloxetine
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 18
Healthy volunteers: no

Brief summary:
The purpose of this study is to explore benefits of duloxetine in enhancing psychological resilience and to understand the relevance of inhibiting of both serotonin (5HT) and norepinephrine (NE)to therapeutic responses.

Detailed description:
This is an investigator-initiated, single-site study consisting of 8 weeks of open-label, fixed-dose treatment with duloxetine (30mg-60mg/day) in patients with Major Depressive Disorder (MDD).

Arms:
arm 1: Open label treatment with Duloxetine for 8 weeks with dosing from 30-60 mg.

Interventions: intervention 1: Duloxetine
Intervention descriptions: intervention 1: Open label treatment with Duloxetine for 8 wks. Dose 30-60 mg.

Protocol document: