Conditions: Insomnia
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 12
Healthy volunteers: no

Brief summary:
This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia. The primary aim was to assess cortisol reactivity before and after long-term (6 weeks) administration of eszopiclone. It was hypothesized that treatment with eszopiclone would result in a significant reduction in plasma cortisol response to the DEX/CRH test following treatment of insomnia with standard dose of eszopiclone.

Detailed description:
see above

Arms:
arm 1: Standard dosing of drug for 6 weeks for insomnia

Interventions: intervention 1: eszopiclone
Intervention descriptions: intervention 1: 6 weeks standard oral therapy

Protocol document: