Conditions: Overactive Bladder (OAB) With Symptoms of Frequency, Urgency, and Urgency
Keywords: BIOAVAILABILITY FOOD EFFECT
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 20
Healthy volunteers: yes

Brief summary:
This Is A Study Of Bioavailability And Food Effect For Fesoterodine.

Detailed description:
To estimate the bioavailability of three different 4 mg fesoterodine ER beads-incapsule formulations compared to 4 mg fesoterodine marketed ER tablets under fasting and fed conditions.

Arms:
arm 1: 4 mg fesoterodine IR beads in capsule under fasting condition arm 2: 4 mg fesoterodine 10% coated ER beads in capsule under fasting condition arm 3: 4 mg fesoterodine 15% coated ER beads in capsule under fasting condition. arm 4: 4 mg fesoterodine 20% coated ER beads in capsule under fasting condition. arm 5: 4 mg fesoterodine ER tablets under fasting condition. arm 6: 4 mg fesoterodine TBD % coated ER beads in capsule under fed condition.

Interventions: intervention 1: fesoterodine intervention 2: fesoterodine intervention 3: fesoterodine intervention 4: fesoterodine intervention 5: fesoterodine intervention 6: fesoterodine
Intervention descriptions: intervention 1: single dose of beads in capsule intervention 2: single dose of beads in capsule intervention 3: single dose of beads in capsule intervention 4: single dose of beads in capsule intervention 5: single dose of tablet intervention 6: single dose of beads in capsule

Protocol document: