Conditions: Pain
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 18
Healthy volunteers: no

Brief summary:
This study is a methodology study designed to discover whether a brain imaging technology is a better way of compare the relative sensitivities of fMRI and subjective psychometric assessments of pain to multiple doses of pregabalin and tramadol SR in a cross-over clinical study design.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Placebo intervention 2: Pregabalin intervention 3: Tramadol SR
Intervention descriptions: intervention 1: BID intervention 2: Dose 75 mg titrated to 150 mg, bid intervention 3: Dose 50mg titrated to 200 mg, bid

Protocol document: