Conditions: Non Small Cell Lung Cancer Small Cell Lung Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 109
Healthy volunteers: no

Brief summary:
This study is a multinational study to compare enzastaurin versus placebo in the treatment of patients with brain metastases of lung cancer. Approximately 108 patients will be randomly assigned to receive either enzastaurin or placebo after having completed whole brain radiotherapy.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: enzastaurin intervention 2: placebo
Intervention descriptions: intervention 1: 1125 mg loading dose then 500 mg, oral, daily, until disease progression intervention 2: oral, daily

Protocol document: