Conditions: Hypercholesterolemia
Keywords: Cardiovascular Diseases
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 12
Healthy volunteers: yes

Brief summary:
The purpose of this study is to estimate the relative bioavailability of the commercial tablet with one prototype extemporaneous preparation suspension formulation, to assist with internal decision making on formulation development.

Detailed description:
Estimation of Relative Bioavailability

Arms:
arm 1: Extemporaneous preparation suspension Atorvastatin prototype formulation arm 2: Commercial atorvastatin tablet (Lipitor®)

Interventions: intervention 1: Atorvastatin suspension intervention 2: Lipitor
Intervention descriptions: intervention 1: A single dose of 80 mg Atorvastatin suspension intervention 2: A single dose of 80 mg Lipitor tablet

Protocol document: