Conditions: Hepatitis B Chronic Hepatitis B
Keywords: HBeAg-positive, chronic hepatitis B telbivudine entecavir viral kinetics
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 44
Healthy volunteers: no

Brief summary:
This exploratory study is designed to determine the early viral kinetic profile during treatment with telbivudine or entecavir at multiple time points over 12 weeks.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Entecavir intervention 2: Telbivudine
Intervention descriptions: intervention 1: Entecavir 0.5 mg once daily for 12 weeks. intervention 2: Telbivudine 600 mg once daily for 12 weeks.

Protocol document: