Conditions: Pulmonary Disease, Chronic Obstructive Lung Diseases Respiratory Tract Diseases Chronic Obstructive Airway Disease COPD
Keywords: Safety Pharmacokinetics Pharmacodynamics PF-03635659 COPD
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 22
Healthy volunteers: no

Brief summary:
PF-03635659 is being developed for the treatment of chronic obstructive pulmonary disease. This is a study to examine the safety, pharmacokinetics and pharmacodynamics of PF-03635659 in patients with Chronic Obstructive Pulmonary Disease (COPD).

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: placebo intervention 2: active comparator intervention 3: Low Dose PF-03635659 intervention 4: Mid Dose PF-03635659 intervention 5: High Dose PF-03635659
Intervention descriptions: intervention 1: oral inhaled formulation, single dose intervention 2: oral inhaled formulation, single dose intervention 3: oral inhaled formulation, single dose, low dose intervention 4: oral inhaled formulation, single dose, mid dose intervention 5: oral inhaled formulation, single dose, high dose

Protocol document: