Conditions: Urinary Tract Infection
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 271
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the efficacy of ertapenem sodium (Invanz) in treatment of complicated urinary tract infections with respect to the proportion of patients with a favorable microbiological response at 5-9 days post therapy.

Detailed description:

Arms:
arm 1: ertapenem sodium arm 2: ceftriaxone sodium

Interventions: intervention 1: ertapenem sodium (MK0826) intervention 2: Comparator: ceftriaxone sodium
Intervention descriptions: intervention 1: a single daily dose of ertapenem sodium 1.0g IV infused over 30 minutes, for 7-14 days (patients may be switched to oral ciprofloxacin after 3 doses of IV therapy if needed) intervention 2: a single daily dose of ceftriaxone 2.0g IV infused over 30 minutes, for 7-14 days (patients may be switched to oral ciprofloxacin after 3 doses of IV therapy)

Protocol document: