Conditions: HIV Infections
Keywords: HIV treatment naïve
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 30
Healthy volunteers: no

Brief summary:
The purpose of this study is:

1. To assess and characterize the PK and PD of PRO 140 administered IV
2. To assess the antiviral activity of PRO 140
3. To assess the safety and tolerability of PRO 140

Detailed description:

Arms:
arm 1: 10 mg/kg PRO 140, one IV dose (N=10) arm 2: 5 mg/kg PRO 140, one IV dose (N=10) arm 3: Placebo, one IV dose (N=10)

Interventions: intervention 1: PRO 140 intervention 2: PRO 140 intervention 3: Placebo
Intervention descriptions: intervention 1: 10 mg/kg PRO 140, one IV dose (N=10) intervention 2: 5 mg/kg PRO 140, one IV dose (N=10) intervention 3: PBO, one IV dose (N=10)

Protocol document: