Conditions: Alzheimer's Disease
Keywords: Alzheimer's disease amyloid imaging antibody
Allocation: RANDOMIZED | Intervention model: 
Enrollment: 36
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether multiple dose administration is safe and well tolerated in patients with mild to moderate Alzheimer's Disease.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: PF-04360365 10 mg/kg intervention 2: PF-04360365 7.5 mg/kg intervention 3: placebo
Intervention descriptions: intervention 1: 10 mg/kg every 90 days (5 total doses) intervention 2: 10 mg/kg loading dose followed by 7.5 mg/kg monthly maintenance dosing (total of 13 doses) intervention 3: placebo administered every 90 days or monthly to match experimental treatment arms.

Protocol document: