Conditions: Post-surgical Dental Pain
Keywords: dental pain paracetamol Post-surgical dental pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 401
Healthy volunteers: no

Brief summary:
GlaxoSmithKline will be conducting this trial to compare analgesic efficacy of paracetamol 1000 mg vs 650 mg. The post-surgical dental pain model will be used to evaluate the analgesic efficacy of paracetamol. Each subject will be enrolled in the study for up to six weeks. The duration of the entire study will be approximately 18 weeks. Each subject will have to come to the clinic for three visits (Screening, Treatment and Follow up visits).

Detailed description:

Arms:
arm 1: Paracetamol 1000mg arm 2: Paracetamol 650 mg arm 3: Placebo

Interventions: intervention 1: Paracetamol 1000 mg intervention 2: Paracetamol 650 mg intervention 3: Placebo
Intervention descriptions: intervention 1: Paracetamol 1000mg intervention 2: Paracetamol 650 mg intervention 3: Placebo

Protocol document: