Conditions: Compulsive Sexual Behavior
Keywords: Impulse Control Disorder Compulsive Sexual Behavior
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 7
Healthy volunteers: no

Brief summary:
The goal of the proposed study is to evaluate the efficacy and safety of naltrexone in compulsive sexual behavior. Twenty subjects with DSM-IV compulsive sexual behavior will receive 8 weeks of naltrexone or placebo. The hypothesis to be tested is that naltrexone will be effective in reducing the urges to act out sexually in patients with compulsive sexual behavior. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Detailed description:
The proposed study will consist of 8 weeks of treatment with either naltrexone or placebo in 20 subjects with compulsive sexual behavior.

Arms:
arm 1: Naltrexone 50mg-150mg by mouth per day. arm 2: Placebo pills (1-3 pills daily) depending upon dose prescribed by study physician

Interventions: intervention 1: Naltrexone intervention 2: Sugar pill
Intervention descriptions: intervention 1: daily intervention 2: daily

Protocol document: