Conditions: Induction of Labor
Keywords: Cervical Ripening Rate of Cesearean Section
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: no

Brief summary:
The purpose of this study is to specifically investigate the efficacy of an alternative pharmacologic cervical ripening agent, misoprostol, versus the standard oxytocin, as an adjunct to Foley balloon for induction of the unfavorable cervix.

Detailed description:
The design of this study is a randomized, controlled study with two arms. Both groups will undergo placement of a Foley catheter, through the external and internal os of the cervix, according to standard practice. In group A, receiving intravenous infusion of oxytocin, will serve as the control group as it is standard protocol at Aultman Hospital. Group B, intravaginal placement of misoprostol, will serve as the experimental group. The expected duration of participation begins at induction of labor and concludes at time of delivery.

Arms:
arm 1: Foley balloon placement with intravenous low dose oxytocin administration starting 2 milliunits per minute. arm 2: Misoprostol, 25 mcg, is placed intravaginally into the posterior fornix of the vagina in conjunction with Foley balloon placement

Interventions: intervention 1: Oxytocin intervention 2: Misoprostol
Intervention descriptions: intervention 1: Foley balloon placement with intravenous low dose oxytocin administration starting 2 milliunits per minute. intervention 2: Misoprostol, 25 mcg, is placed intravaginally into the posterior fornix of the vagina in conjunction with Foley balloon placement

Protocol document: