Conditions: Rheumatoid Arthritis
Keywords: Signs and Symptoms Autoimmune Diseases Joint Diseases Arthritis Connective Tissue Diseases Arthritis, Rheumatoid Rheumatic Diseases Predniso(lo)ne
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 350
Healthy volunteers: no

Brief summary:
The purpose of the study is to compare the safety and efficacy, with regards to the signs and symptoms, of MR prednisone (Lodotra®) versus placebo in combination with standard Disease Modifying Anti-Rheumatic Drug (DMARD) treatment in patients with active rheumatoid arthritis.

Detailed description:
Study with completed results acquired from Horizon in 2024.

Arms:
arm 1: Modified Release (MR) prednisone 5 mg arm 2: None

Interventions: intervention 1: MR prednisone intervention 2: Placebo
Intervention descriptions: intervention 1: 1 x 5 mg daily intervention 2: 1x daily

Protocol document: