Conditions: Acne Vulgaris
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 163
Healthy volunteers: no

Brief summary:
A 12-week evaluation of the safety and efficacy of dapsone gel 5% when used with tretinoin gel 0.025% compared with tretinoin gel 0.025% monotherapy in treating moderate to severe facial acne vulgaris

Detailed description:

Arms:
arm 1: Dapsone gel 5% and Tretinoin gel 0.025% arm 2: Tretinoin gel 0.025%

Interventions: intervention 1: Dapsone; Tretinoin intervention 2: Tretinoin
Intervention descriptions: intervention 1: Dapsone topical gel 5%, 1 pea-size amount BID x 12 weeks and Tretinoin gel 0.025%, 1 pea-size amount QD x 12 weeks intervention 2: Tretinoin gel 0.025%, 1 pea-size amount QD x 12 weeks

Protocol document: