Conditions: Diabetes Mellitus, Type 2
Keywords: diabetes type 2
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 484
Healthy volunteers: no

Brief summary:
A study of patients with type 2 diabetes and inadequate glycemic control on two or more oral antihyperglycemic agents comparing adding insulin lispro mid mixture to the oral antihyperglycemic agents to adding insulin glargine to the oral antihyperglycemic agents.

Detailed description:

Arms:
arm 1: Insulin lispro mid mixture (MM) up to three times a day (TID) arm 2: Insulin glargine daily with insulin lispro at mealtime (up to 3 injections) as needed.

Interventions: intervention 1: Insulin lispro mid mixture (MM) intervention 2: Insulin glargine
Intervention descriptions: intervention 1: Patient specific adjusted dose, three times a day (TID), subcutaneous (SC) injection x 36 weeks intervention 2: Patient specific adjusted dose, every day (QD), subcutaneous (SC) injection x 36 weeks

Protocol document: