Conditions: Parkinson's Disease
Keywords: Parkinson's disease PD dyskinesia treatment motor complications
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 2
Healthy volunteers: no

Brief summary:
This study is to determine if Viagra is effective in reducing dyskinesias in patients with Parkinson's Disease.

Detailed description:
Inclusion Criteria:

1. Diagnosis of idiopathic Parkinson's disease.
2. Age \> 40 years.
3. willingness and ability to comply with the study requirements and give informed consent.

Arms:
arm 1: subjects will be randomized to active treatment for 2 weeks, washout for 1 week, then enter the other study arm for two weeks. arm 2: subjects will be randomized to placebo treatment for 2 weeks, washout for 1 week, then enter the other study arm for two weeks.

Interventions: intervention 1: sildenafil intervention 2: Placebo
Intervention descriptions: intervention 1: sildenafil 50mg BID for 2 weeks intervention 2: None

Protocol document: