Conditions: Diabetic Macular Edema
Keywords: Diabetic Macular Edema PVD DME Diabetic Retinopathy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 51
Healthy volunteers: no

Brief summary:
A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with DME.

Detailed description:

Arms:
arm 1: 25µg ocriplasmin intravitreal injection versus sham injection arm 2: 75µg ocriplasmin intravitreal injection versus sham injection arm 3: 125µg ocriplasmin intravitreal injection versus sham injection arm 4: Sham injection

Interventions: intervention 1: ocriplasmin intervention 2: Sham injection
Intervention descriptions: intervention 1: Intravitreal injection, single administration intervention 2: Sham intravitreal injection

Protocol document: