Conditions: Schizophrenia Tobacco Use Disorder Nicotine Dependance
Keywords: schizophrenia varenicline cognition cigarette smoking
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 14
Healthy volunteers: no

Brief summary:
This is an open label pre-post study of the effects of clinical treatment with varenicline on 1) decreasing smoking in schizophrenic patients, 2) improving selected cognitive measures in schizophrenic patients, and 3) psychopathology in schizophrenic patients. Patients are assessed on subjective and objective measures of smoking, selected cognitive measures, and special chemical measures, during baseline testing and during 8 weeks of treatment with varenicline (1-2 mg/day).

Detailed description:

Arms:
arm 1: open label varenicline 2mg/day

Interventions: intervention 1: Varenicline
Intervention descriptions: intervention 1: Varenicline 1-2 mg/day

Protocol document: