Conditions: Parkinson Disease
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 246
Healthy volunteers: no

Brief summary:
To determine if there is any difference in the presence of retinal deterioration in PD patients treated with pramipexole IR versus ropinirole as monitored by comprehensive ophthalmologic assessments from baseline to the end of study at two years.

Detailed description:

Arms:
arm 1: Mirapex tablets three times daily (TID) dosing according to manufacturer's guidelines arm 2: Requip tablets three times daily (TID) dosing according to manufacturer's guidelines

Interventions: intervention 1: Mirapex intervention 2: Requip
Intervention descriptions: intervention 1: Standard marketed product dispensed according to manufacturer's guidelines intervention 2: Standard marketed product dispensed according to manufacturer's guidelines

Protocol document: