Conditions: Pancreatic Neoplasm
Keywords: pancreas cancer; cancer of the pancreas; gemcitabine; chemotherapy; monoclonal antibody; immunotherapy; CD40
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 22
Healthy volunteers: no

Brief summary:
This study aims to seek evidence that activation of certain cells of the immune system will be safe and well tolerated in combination with cytotoxic chemotherapy. Preliminary evidence of clinical anti-tumor activity will be sought.

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: monoclonal antibody intervention 2: chemotherapy
Intervention descriptions: intervention 1: CP-870,893 intravenous administration \[IV\] on day 3 of 4-week cycles intervention 2: gemcitabine 1000 mg/m\^2 intravenous administration \[IV\] q week \[wk\]x3 of 4-week cycles

Protocol document: