Conditions: Pharyngitis
Keywords: sore throat acute pain
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 269
Healthy volunteers: no

Brief summary:
We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind, placebo-controlled conditions.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: Celecoxib intervention 2: Celecoxib intervention 3: celecoxib intervention 4: placebo
Intervention descriptions: intervention 1: dose 1 celecoxib 50 mg followed 6-12 hours later by dose 2 celecoxib 50 mg intervention 2: dose 1 celecoxib 100 mg followed 6-12 hours later by dose 2 placebo intervention 3: dose 1 celecoxib 100 mg followed 6-12 hours later by dose 2 celecoxib 50 mg intervention 4: dose 1 placebo followed 6-12 hours later by dose 2 placebo

Protocol document: