Conditions: Dry Eye Syndromes
Keywords: Dry Eye Syndromes OPC-12759
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 308
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the dose-response of OPC-12759 suspension in dry eye patients

Detailed description:

Arms:
arm 1: 0% OPC-12759 ophthalmic suspension received one drop to both eyes four times a day for 4 weeks. arm 2: 1% OPC-12759 ophthalmic suspension received one drop to both eyes four times a day for 4 weeks. arm 3: 2% OPC-12759 ophthalmic suspension received one drop to both eyes four times a day for 4 weeks.

Interventions: intervention 1: placebo intervention 2: 1% OPC-12759 ophthalmic suspension intervention 3: 2% OPC-12759 ophthalmic suspension
Intervention descriptions: intervention 1: comparison of different dosages of drug intervention 2: comparison of different dosages of drug intervention 3: comparison of different dosages of drug

Protocol document: