Conditions: Type 2 Diabetes
Keywords: T2DM Metformin A1c
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 282
Healthy volunteers: no

Brief summary:
The purpose of this study is to compare reduction in A1C for subjects taking Saxagliptin and Metformin XR vs. uptitrated Metformin XR.

Detailed description:

Arms:
arm 1: Saxagliptin arm 2: Metformin Extended Release

Interventions: intervention 1: Saxagliptin intervention 2: Metformin XR intervention 3: Metformin XR
Intervention descriptions: intervention 1: 5mg oral tablet once daily intervention 2: 500mg oral tablet once daily intervention 3: 750mg, 2 tablets once daily

Protocol document: