Conditions: Carcinoma, Non-Small-Cell Lung
Keywords: CP-751,871, Non-small cell lung cancer, Phase 1
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 19
Healthy volunteers: no

Brief summary:
Investigate safety, tolerability and pharmacokinetics of CP-751,871 when given in combination with carboplatin and paclitaxel in patients with advanced non-small cell lung cancer

Detailed description:

Arms:
arm 1: None

Interventions: intervention 1: CP-751,871 + carboplatin + paclitaxel
Intervention descriptions: intervention 1: Chemotherapy (carboplatin and paclitaxel) and CP-751,871 (6, 10 or 20mg/kg) will be administered by intravenous infusion every three weeks.

Protocol document: