Conditions: Alopecia Alopecia, Androgenetic Baldness
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 42
Healthy volunteers: no

Brief summary:
This study will investigate the safety, tolerability, and pharmacokinetics of new formulation of bimatoprost following topical application in patients with alopecia. Two formulations of bimatoprost will be investigated in Part 1 and a third formulation of bimatoprost will be investigated in Part 2. Part 2 will begin after Part 1 has completed.

Detailed description:

Arms:
arm 1: bimatoprost Formulation A applied topically to the scalp once daily on Day 1 and Days 4-17. arm 2: bimatoprost Formulation B applied topically to the scalp once daily on Day 1 and Days 4-17. arm 3: bimatoprost Formulation C applied topically to the scalp once daily on Day 1 and Days 4-17.

Interventions: intervention 1: bimatoprost Formulation A intervention 2: bimatoprost Formulation B intervention 3: bimatoprost Formulation C
Intervention descriptions: intervention 1: bimatoprost Formulation A applied topically to the scalp once daily on Day 1 and Days 4-17. intervention 2: bimatoprost Formulation B applied topically to the scalp once daily on Day 1 and Days 4-17. intervention 3: bimatoprost Formulation C applied topically to the scalp once daily on Day 1 and Days 4-17.

Protocol document: