Conditions: Schizophrenia
Keywords: Electroconvulsive Therapy
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 39
Healthy volunteers: no

Brief summary:
This study will evaluate electroconvulsive therapy (ECT) in patients who have not responded adequately to clozapine.

Detailed description:
ECT augmentation of clozapine will be compared to clozapine monotherapy in schizophrenic patients who continue to have psychotic symptoms despite optimal treatment with clozapine.

Arms:
arm 1: Electroconvulsive therapy ECT plus clozapine for 8 weeks arm 2: Clozapine for 8 weeks

Interventions: intervention 1: Electroconvulsive Therapy (ECT) intervention 2: Clozapine
Intervention descriptions: intervention 1: ECT will be used to augment clozapine in schizophrenic patients who continue to have psychotic symptoms despite optimal treatment with clozapine. intervention 2: Patients with psychotic symptoms will receive clozapine

Protocol document: