Conditions: Hypertension
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 47
Healthy volunteers: yes

Brief summary:
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.

Detailed description:

Arms:
arm 1: amlodipine arm 2: Placebo to amlodipine

Interventions: intervention 1: Comparator: amlodipine besylate intervention 2: Comparator: Placebo
Intervention descriptions: intervention 1: Two 5 mg tablets amlodipine daily for 6 weeks. intervention 2: Two 5 mg tablets placebo to amlodipine daily for 6 weeks

Protocol document: