Conditions: Nonalcoholic Steatohepatitis (NASH) Hepatic Steatosis
Keywords: Non-alcoholic steatohepatitis Omega-3 fatty acids MRI NASH
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: no

Brief summary:
The current pilot study assesses the use of magnetic resonance imaging (MRI) to quantify hepatic steatosis. It will provide preliminary data regarding the use of omega-3 fatty acid supplementation (Lovaza) for the treatment of nonalcoholic steatohepatitis (NASH).

Detailed description:

Arms:
arm 1: Participants receive 4 milligrams (mg) daily of omega-3-acid ethyl esters (Lovaza) and dietary counseling for 24 weeks arm 2: Participants receive daily placebo and dietary counseling for 24 weeks

Interventions: intervention 1: Omega-3-acid ethyl esters (Lovaza) intervention 2: Placebo
Intervention descriptions: intervention 1: 4 milligrams daily omega-3-acid ethyl esters (Lovaza) with dietary counseling for 24 weeks. intervention 2: Daily placebo with dietary counseling for 24 weeks.

Protocol document: