Conditions: Urinary Bladder, Overactive
Keywords: Urgency YM178 Urinary incontinence Mirabegron Micturition Frequency Urinary urgency incontinence Overactive Bladder
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 2030
Healthy volunteers: no

Brief summary:
The study is intended to test efficacy, safety and tolerability of two doses of once daily (qd) Mirabegron against placebo to treat patients with symptoms of overactive bladder.

Detailed description:

Arms:
arm 1: Participants received matching mirabegron placebo tablets orally once a day for 12 weeks. arm 2: Participants received mirabegron 25 mg tablets orally once a day for 12 weeks. arm 3: Participants received mirabegron 50 mg tablets orally once a day for 12 weeks.

Interventions: intervention 1: Mirabegron intervention 2: Placebo
Intervention descriptions: intervention 1: Mirabegron tablets intervention 2: Matching mirabegron placebo tablets.

Protocol document: