Conditions: Cholangitis
Keywords: Cholangitis; Cholangiopancreatography, Endoscopic Retrograde; stents; cholestasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 114
Healthy volunteers: no

Brief summary:
Cholangitis is the most prevalent infectious complication of ERCP. Stenting of biliary strictures and stenosis is one of important risk factors for post-ERCP cholangitis. Adding antibiotics to contrast media has proposed in some studies for prevention of cholangitis but remains controversial. In this study we compare effect of adding gentamicin versus placebo in preventing cholangitis in patients who undergone endoscopic stenting for non-calculus strictures and stenosis.

Detailed description:

Arms:
arm 1: adding 10mg gentamicin to every 10 ml of contrast media arm 2: Identical placebo

Interventions: intervention 1: gentamicin intervention 2: Placebo
Intervention descriptions: intervention 1: 10mg per 10ml of contrast media intervention 2: Distilled water

Protocol document: