Conditions: Thrombosis
Keywords: Anticoagulation Prophylaxis Desirudin Direct thrombin inhibitor Heparin-induced thrombocytopenia
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 516
Healthy volunteers: no

Brief summary:
The objective of this trial is to demonstrate the clinical utility of fixed-dose SC Desirudin for the prophylaxis of thrombosis as an alternative to heparin-based anticoagulation.

Detailed description:
Hospitalized patients who require DVT prophylaxis and who are not good candidates for heparin-based anti-coagulation were eligible.

Arms:
arm 1: desirudin 15 mg twice daily for a minimum of 5 days

Interventions: intervention 1: Desirudin
Intervention descriptions: intervention 1: Desirudin SC 15mg q12h

Protocol document: