Conditions: Perennial Allergic Rhinitis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 351
Healthy volunteers: no

Brief summary:
This study was conducted to see if mometasone nasal spray is efficaceous for the treatment of perennial allergic rhinitis. Patients will be randomized to active mometasone, placebo mometasone, active fluticasone, or placebo fluticasone.

Detailed description:

Arms:
arm 1: Placebo to mometasone furoate nasal spray, made to be indistinguishable from mometasone furoate nasal spray arm 2: Placebo to fluticasone propionate nasal spray, made to be indistinguishable from fluticasone propionate nasal spray arm 3: Mometasone furoate nasal spray 200 μg/day(QD) arm 4: Fluticasone Propionate nasal spray 200 μg/day, twice per day (BID)

Interventions: intervention 1: Placebo for MF intervention 2: Placebo for FP intervention 3: Mometasone intervention 4: Fluticasone
Intervention descriptions: intervention 1: Placebo to mometasone furoate nasal spray, indistinguishable from mometasone furoate nasal spray. Patients in this arm take 2 sprays per nostril once a day for 2 weeks intervention 2: Placebo to fluticasone nasal spray, indistinguishable from fluticasone propionate nasal spray. Patients in this arm take 2 sprays per nostril twice a day for 2 weeks intervention 3: Mometasone furoate nasal spray. Patients in this arm take 2 sprays per nostril once a day for 2 weeks intervention 4: Fluticasone propionate nasal spray. Patients in this arm take 2 sprays per nostril twice a day for 2 weeks

Protocol document: