Conditions: Osteopenia
Keywords: Postmenopausal osteoporosis osteopenia zoledronic acid Osteopenia (osteoporosis prevention)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 581
Healthy volunteers: no

Brief summary:
Osteoporosis prevention is important in patients with osteopenia (low bone density). This study will test the safety and efficacy of zoledronic acid in patients diagnosed with osteopenia.

Detailed description:

Arms:
arm 1: Zoledronic acid 5 mg intravenous (i.v.) given at randomization and Month 12 arm 2: Zoledronic acid 5 mg intravenous (i.v.) given at randomization and placebo at Month 12 arm 3: Placebo given at randomization and Month 12

Interventions: intervention 1: Zoledronic Acid intervention 2: Placebo
Intervention descriptions: intervention 1: Zoledronic acid 5 mg intravenous intervention 2: Physiologic 0.9% normal saline

Protocol document: