Conditions: Psoriasis
Keywords: Plaque Type Psoriasis Topical
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 30
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the safety and efficacy of AN2728 Ointment, 5%, compared to Ointment Vehicle, applied twice daily for 12 weeks, in the treatment of plaque type psoriasis

Detailed description:
This is a single center, randomized, double-blind, vehicle-controlled, bilateral design. Patients will apply both test articles, AN2728 Ointment, 5%, and Ointment Vehicle twice daily for 12 weeks. The assigned study medication will be applied to two comparable treatment targeted plaques identified at baseline. One test article will be applied to one plaque and the other test article to an anatomically distinct plaque. All efficacy evaluations will be measured from only the two plaques identified at the baseline visit.

Arms:
arm 1: AN2728 Ointment, 5% arm 2: AN2728 Ointment vehicle

Interventions: intervention 1: AN2728 intervention 2: Ointment vehicle
Intervention descriptions: intervention 1: AN2728 Ointment, 5%, twice daily for 12 weeks intervention 2: Ointment vehicle, twice daily for 12 weeks

Protocol document: