Conditions: Type 2 Diabetes
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 30
Healthy volunteers: no

Brief summary:
This study will assess, over a 4-week treatment period, the safety and efficacy of the addition of sitagliptin to metformin in participants with type 2 diabetes mellitus (T2DM) who failed to achieve glycemic control on metformin monotherapy.

Detailed description:

Arms:
arm 1: Sitagliptin as add-on therapy to a stable dose of metformin

Interventions: intervention 1: Sitagliptin phosphate intervention 2: Metformin
Intervention descriptions: intervention 1: Sitagliptin 100 mg tablet by mouth once daily for 4 weeks. intervention 2: Stable dose of metformin tablet(s) by mouth (at least 1000 mg/day) for 4 weeks.

Protocol document: