Conditions: Prevention
Keywords: Gastric ulcer Duodenal ulcer Low-dose aspirin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 427
Healthy volunteers: no

Brief summary:
To assess the efficacy of D961H 20 mg once daily (q.d.) versus placebo in continuous treatment involving patients with a history of gastric and/or duodenal ulcers receiving daily Low-dose aspirin therapy by evaluating time from randomisation to occurrence of gastric and/or duodenal ulcers.

Detailed description:

Arms:
arm 1: Esomeprazole 20mg once daily oral arm 2: Placebo once daily oral

Interventions: intervention 1: Esomeprazole intervention 2: Placebo
Intervention descriptions: intervention 1: 20mg, capsule, 72 weeks intervention 2: Placebo, capsule, 72 weeks

Protocol document: