Conditions: Psoriasis
Keywords: dose response; PASI 75 response endpoint; subjects with moderate to severe chronic plaque psoriasis
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 197
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine the effectiveness and safety, over 12 weeks, of 3 dosing regimens of CP-690,550 for the treatment of adults with moderate to severe chronic plaque psoriasis.

Detailed description:

Arms:
arm 1: None arm 2: None arm 3: None arm 4: None

Interventions: intervention 1: CP-690,550 intervention 2: CP-690,550 intervention 3: CP-690,550 intervention 4: Placebo
Intervention descriptions: intervention 1: tablets, 2 mg BID for 12 weeks intervention 2: tablets, 5 mg BID for 12 weeks intervention 3: tablets, 15 mg BID for 12 weeks intervention 4: tablets, BID for 12 weeks

Protocol document: