Conditions: Asthma
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 91
Healthy volunteers: no

Brief summary:
The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult participants with acute asthma.

Detailed description:

Arms:
arm 1: Montelukast 7 mg IV administration arm 2: Montelukast 14 mg IV administration arm 3: Aminophylline 250 mg IV drip administration

Interventions: intervention 1: montelukast sodium intervention 2: montelukast sodium intervention 3: aminophylline hydrate
Intervention descriptions: intervention 1: Montelukast 7 mg single injection (IV bolus administration) over 2-3 minutes intervention 2: Montelukast 14 mg single injection (IV bolus administration) over 5 minutes intervention 3: Aminophylline 250 mg IV drip infusion over 60 minutes

Protocol document: