Conditions: Fibromyalgia
Keywords: Milnacipran Pain Durability of Effect Loss of Therapeutic Response Fatigue Forest Research Institute Savella ®
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 340
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the durability of effect of milnacipran for the treatment of fibromyalgia in patients receiving long-term milnacipran treatment and to characterize the effects of milnacipran on multiple symptoms of fibromyalgia, as demonstrated by changes in symptoms following the discontinuation of milnacipran.

Detailed description:

Arms:
arm 1: Placebo tablets administered orally twice daily arm 2: Milnacipran tablets administered orally twice daily

Interventions: intervention 1: Placebo intervention 2: Milnacipran
Intervention descriptions: intervention 1: Placebo tablets administered orally twice daily intervention 2: Milnacipran tablets administered orally twice daily

Protocol document: