Conditions: Trichotillomania
Keywords: Trichotillomania Hair-pulling
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 50
Healthy volunteers: no

Brief summary:
This is a 12-week, double-blind study of N-Acetyl Cysteine in the treatment of trichotillomania

Detailed description:
The goal of the proposed study is to evaluate the efficacy and safety of N-Acetyl Cysteine (NAC) in trichotillomania. Forty subjects with DSM-IV trichotillomania will receive 12 weeks of double-blind NAC or placebo. The hypothesis to be tested is that NAC will be effective and well tolerated in patients with trichotillomania compared to placebo. The proposed study will provide needed data on the treatment of a disabling disorder that currently lacks a clearly effective treatment.

Arms:
arm 1: N-Acetyl Cysteine arm 2: Placebo

Interventions: intervention 1: Placebo intervention 2: N-Acetyl Cysteine
Intervention descriptions: intervention 1: daily intervention 2: 600mg capsules in varying doses for 12 weeks.

Protocol document: