Conditions: Pain
Keywords: dental pain multiple dose ibuprofen third molar extraction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 106
Healthy volunteers: no

Brief summary:
The study hypothesis is that single and multiple doses of ibuprofen 600 mg ER caplets provide analgesic efficacy superior to placebo over 12-hour dosing intervals.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Ibuprofen 600 mg ER intervention 2: Placebo
Intervention descriptions: intervention 1: One 600 mg caplet dosed at 0, 12, 24 and 36 hours intervention 2: One placebo caplet dosed at times 0, 12, 24 and 36 hours

Protocol document: