Conditions: Heart Failure, Congestive
Keywords: carvedilol phosphate ß-blocker SK&F-105517-D Chronic heart failure(CHF)
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 41
Healthy volunteers: no

Brief summary:
The primary objective of this study is to evaluate the safety and tolerability of SK\&F-105517-D in japanese patients with chronic heart failure.

Detailed description:

Arms:
arm 1: SK\&F-105517-D 10-80 mg/day arm 2: Carvedilol-IR 5-20 mg/day

Interventions: intervention 1: SK&F-105517-D 10 mg capsule intervention 2: Carvedilol-immediate release (IR) 2.5 mg tablet intervention 3: SK&F-105517-D 20 mg capsule intervention 4: SK&F-105517-D 40 mg capsule intervention 5: Carvedilol-IR 10 mg tablet
Intervention descriptions: intervention 1: 1 capsule once a day intervention 2: 1 or 2 tablet(s) twice a day intervention 3: 1 capsule once a day intervention 4: 1 or 2 capsule(s) once a day intervention 5: 1 tablet twice a day

Protocol document: