Conditions: Non-small Cell Lung Cancer
Keywords: NSCLC Metastatic Stage IV NSCLC Limited Volume Stage IV Non-small Cell Lung Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 11
Healthy volunteers: no

Brief summary:
Primary goal of the study is to assess the overall survival of the addition of hypofractionated image guided radiotherapy concurrently with Docetaxel and cisplatin. Survival will be assessed at 1 year from the date of study enrollment to date of death.

Detailed description:

Arms:
arm 1: Chemotherapy only arm 2: Chemotherapy and hypofractionated image guided radiotherapy

Interventions: intervention 1: Docetaxel and cisplatin intervention 2: Docetaxel and cisplatin Plus Hypofractionated Radiotherapy
Intervention descriptions: intervention 1: Docetaxel 75 mg/m2 and cisplatin 75 mg/m2 IV repeated every 21 days for 2 additional cycles. For patients randomized to group 1, the chemotherapy is identical to that administered for the first 2 cycles intervention 2: Docetaxel 75 mg/m2 and cisplatin 75 mg/m2 IV for 2 cycles along with hypofractionated radiotherapy to all known sites of disease

Protocol document: