Conditions: Stress Disorders, Post-Traumatic
Keywords: PTSD Paroxetine Subthreshold
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 12
Healthy volunteers: no

Brief summary:
The purpose of this study is: 1) To document the effectiveness and tolerability of paroxetine for the treatment of subthreshold posttraumatic stress disorder (PTSD) in veterans in the early post-deployment period; and 2) To determine the potential efficacy of paroxetine in preventing the progression of anxiety symptoms to PTSD and other anxiety disorders, and improving overall veteran function.

Detailed description:
See brief summary

Arms:
arm 1: Paroxetine 10 mg-40 mg or placebo; flexible dosing; 12-week duration. arm 2: None

Interventions: intervention 1: Paroxetine intervention 2: Placebo
Intervention descriptions: intervention 1: Paroxetine 10 mg-40 mg or placebo; flexible dosing; 12-week duration. intervention 2: Placebo: same as paroxetine (active comparator)

Protocol document: