Conditions: HIV
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 12
Healthy volunteers: yes

Brief summary:
The purpose of this study is to compare the sweetness of 2 new atazanavir powder for oral use (POU) formulations to the current atazanavir POU in healthy participants and to select 1 atazanavir POU that has the sweetness most similar to the current atazanavir POU.

Detailed description:
This study is a taste assessment study designed to select a new atazanavir powder for oral use (POU) formulation that is similar in sweetness to the current POU formulation. Participants were to taste and then spit out the POU formulations, without swallowing them. Study Classification: Other. This is a taste study

Arms:
arm 1: None arm 2: None arm 3: None

Interventions: intervention 1: Atazanavir (current formulation) intervention 2: Atazanavir, powder for oral use 1 (POU1) intervention 3: Atazanavir (POU2)
Intervention descriptions: intervention 1: Solution, oral, atazanavir 15 mg/5 mL with 10% aspartame, single dose intervention 2: Solution, oral, atazanavir 15 mg/5 mL with 4.2% aspartame, single dose intervention 3: Solution, oral, atazanavir 15 mg/5 mL with 4.2% aspartame and sucralose, single dose

Protocol document: