Conditions: Secondary Hyperparathyroidism Dialysis
Keywords: Dialysis Hyperparathyroidism Zemplar
Allocation: NON_RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 147
Healthy volunteers: no

Brief summary:
Prospective, non-randomized, multi-center study to assess the efficacy and safety of paricalcitol injection or oral administered over 6 months to patients with secondary hyperparathyroidism on dialysis.

Detailed description:

Arms:
arm 1: ABT-358 Zemplar arm 2: ABT-358 Zemplar

Interventions: intervention 1: Paricalcitol injection intervention 2: Paricalcitol capsules
Intervention descriptions: intervention 1: Most recent iPTH level in pg/mL divided by 100 = dose in mcg; dose is rounded down to nearest mcg and administered 3x weekly intervention 2: Most recent iPTH level in pg/mL divided by 80 = dose in mcg; dose is rounded down to nearest mcg and administered 3x weekly

Protocol document: