Conditions: Type 2 Diabetes Mellitus
Keywords: sitagliptin type 2 diabetes combination therapy
Allocation: NA | Intervention model: SINGLE_GROUP
Enrollment: 108
Healthy volunteers: no

Brief summary:
This study will compare the effect of a new oral agent for type 2 diabetes, sitagliptin, in comparison to thiazolidinediones as the third-line oral agent, in patients with type 2 diabetes mellitus.

Detailed description:
The aim of this protocol is to determine the non-inferiority of the effectiveness of sitagliptin compared to a control group of patients treated with thiazolidinediones as add-on therapy, in low-income ethnic minority type 2 diabetic patients who are failing to maintain adequate control with maximal doses of metformin and a sulfonylurea agent.

Arms:
arm 1: Sitagliptin 100 mg once daily

Interventions: intervention 1: Sitagliptin
Intervention descriptions: intervention 1: Sitagliptin 100 mg by mouth once daily

Protocol document: