Conditions: Psoriasis Vulgaris
Allocation: RANDOMIZED | Intervention model: SINGLE_GROUP
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of the study is to evaluate the anti-psoriatic effect of LEO 90100 cutaneous spray ointment, using the psoriasis plaque test modified from the method developed by KJ Dumas and JR Scholtz.

Detailed description:

Arms:
arm 1: LEO 90100 cutaneous spray, ointment, is a new product containing calcipotriol 50 mcg/g and betamethasone 0.5 mg/g (as dipropionate). arm 2: Vehicle cutaneous spray, ointment, with betamethasone 0.5 mg/g (as dipropionate) arm 3: LEO 90100 vehicle served as a negative control for the two cutaneous spray ointments with active ingredients. arm 4: Calcipotriol 50 mcg/g plus betamethasone 0.5 mg/g (as dipropionate)

Interventions: intervention 1: LEO90100 cutaneous spray, ointment intervention 2: LEO 90100 cutaneous spray, ointment, vehicle with betamethasone dipropionate intervention 3: LEO 90100 cutaneous spray, ointment, vehicle intervention 4: Daivobet® ointment
Intervention descriptions: intervention 1: once daily application, 4 weeks intervention 2: once daily application, 4 weeks intervention 3: once daily application, 4 weeks intervention 4: once daily application, 4 weeks

Protocol document: