Conditions: Acute Respiratory Distress Syndrome Influenza H1N1 Influenza
Keywords: ARDS H1N1 Influenza Statin
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 7
Healthy volunteers: no

Brief summary:
To assess the efficacy and safety of oral rosuvastatin in patients with suspected or confirmed influenza who require intensive care unit (ICU) admission due to respiratory distress.

Detailed description:
Hypothesis: Rosuvastatin therapy will improve mortality and reduce the need for mechanical ventilation in patients experiencing respiratory distress as a complication of influenza.

Arms:
arm 1: Placebo arm 2: Experimental arm

Interventions: intervention 1: Rosuvastatin (crestor) intervention 2: Placebo
Intervention descriptions: intervention 1: 20 mg tablets once daily x max 28 days or for an additional 3 days following ICU discharge intervention 2: Placebo tablet identical to active therapy. 1 tablet per day

Protocol document: