Conditions: Primary Renal Transplant
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 40
Healthy volunteers: no

Brief summary:
The purpose of this study is to determine whether Campath-1H induction therapy and the associated lymphocyte depletion will permit long-term, rejection free renal allograft function in the absence of maintenance calcineurin inhibitor (CI) therapy.

Detailed description:

Arms:
arm 1: Standard of Care CNI immunosuppression arm 2: Calcineurin inhibitor withdrawal

Interventions: intervention 1: Calcineurin inhibitor withdrawal
Intervention descriptions: intervention 1: stopping tacrolimus or cyclosporine in subjects who received Campath-1H induction therapy

Protocol document: