Conditions: Myocardial Infarction
Keywords: STEMI ACS
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 70
Healthy volunteers: no

Brief summary:
Safety and efficacy of adjunctive antiplatelet therapy prior to primary percutaneous intervention (PCI) in patients with ST-Elevation Myocardial Infarction (STEMI)

Detailed description:
Patients with STEMI who are to undergo primary PCI will be randomized to an intravenous (iv) bolus of placebo vs. PRT060128 prior to angiography.

Arms:
arm 1: Placebo for each Dose cohort: 10, 20, 40, and 60 mg arm 2: Experimental drug for each Dose cohort: 10, 20, 40, and 60 mg

Interventions: intervention 1: placebo intervention 2: PRT060128 Potassium
Intervention descriptions: intervention 1: administration of iv bolus prior to angiography intervention 2: administration of iv bolus prior to angiography

Protocol document: