Conditions: Hypotension, Orthostatic
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 24
Healthy volunteers: no

Brief summary:
The purpose of this clinical study is to evaluate the clinical effect of midodrine hydrochloride (ProAmatine®) compared to placebo in patients with orthostatic hypotension by measuring the time to onset of near syncopal symptoms and assessing several cardiovascular measurements, such as heart rate, blood pressure, and ECG, using the tilt table test.

Detailed description:

Arms:
arm 1: None arm 2: None

Interventions: intervention 1: Midodrine hydrochloride intervention 2: Placebo
Intervention descriptions: intervention 1: one dose, 10-30mg, given orally intervention 2: Placebo

Protocol document: