Conditions: Lower Urinary Tract Symptoms Bladder Outlet Obstruction
Keywords: Beta-3 Receptor Agonist YM178 Men Lower Urinary Tract Symptoms Bladder Outlet Obstruction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 200
Healthy volunteers: no

Brief summary:
This study examined the safety, tolerability, and efficacy of mirabegron (YM178) compared to placebo.

Detailed description:

Arms:
arm 1: Participants received matching mirabegron placebo tablets orally once daily for 12 weeks. arm 2: Participants received 50 mg mirabegron tablets orally once daily for 12 weeks. arm 3: Participants received 100 mg mirabegron tablets orally once daily for 12 weeks.

Interventions: intervention 1: Mirabegron intervention 2: Placebo
Intervention descriptions: intervention 1: oral intervention 2: oral

Protocol document: