Conditions: Postherpetic Neuralgia
Keywords: Postherpetic Neuralgia, PHN, Shingles,
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 187
Healthy volunteers: no

Brief summary:
The purpose of the study is to evaluate the efficacy of retigabine vs. placebo in reducing pain associated with post-herpetic neuralgia.

Detailed description:
This is a Phase 2a proof of concept study evaluating the safety/efficacy of retigabine vs. placebo in patients with post-herpetic neuralgia. After screening, patients will enter a maximum 6 week titration period followed by a 4 week maintenance period and a 3 week taper phase.

Arms:
arm 1: Retigabine arm 2: Placebo

Interventions: intervention 1: Retigabine intervention 2: Placebo
Intervention descriptions: intervention 1: 150mg/day up to 900mg/day intervention 2: daily

Protocol document: