Conditions: Antidepressant Induced Sexual Dysfunction
Keywords: Antidepressant Induced Sexual Dysfunction Depression Sexual Dysfunction
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 45
Healthy volunteers: no

Brief summary:
The purpose of this study is to find out whether Maca Root is effective for treating sexual dysfunction in females that is caused by antidepressant drugs. An additional aim of the study is to document the safety and tolerability of maca root, as well as any potential side effects that it causes.

Detailed description:
This is a 12-week, double-blind, placebo-controlled trial comparing maca root (3.0 g/day) versus an inactive placebo in female outpatients with SSRI/SNRI-induced sexual dysfunction whose depression had remitted with SSRI treatment. Outcome measures include improvement in sexual functioning as per the Arizona Sexual Experience Scale (ASEX) and the Massachusetts General Hospital Sexual Function Questionnaire (MGH-SFQ).

Arms:
arm 1: Subjects in this arm will be given 3g/day of maca root for 12 weeks arm 2: Subjects in this arm will receive inactive placebo for 12 weeks.

Interventions: intervention 1: Maca Root intervention 2: Placebo
Intervention descriptions: intervention 1: 3g/day of Maca Root for 12 weeks. intervention 2: Placebo provided by research pharmacy daily for 12 weeks.

Protocol document: