Conditions: Rhinitis, Allergic, Seasonal
Keywords: Levocetirizine Xyzal Rhinitis Allergic Seasonal Ragweed
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 418
Healthy volunteers: no

Brief summary:
To compare the clinical efficacy of levocetirizine 5 mg and montelukast 10 mg on symptoms of seasonal allergic rhinitis occurring in subjects exposed to ragweed pollen in an environmental exposure unit.

Detailed description:

Arms:
arm 1: Placebo was administered orally on Days 1 and 2. arm 2: 10 mg of Montelukast (MLKT) was administered orally on Days 1 and 2. arm 3: 5 mg of Levocetirizine (LCTZ) was administered orally on Days 1 and 2.

Interventions: intervention 1: Placebo intervention 2: Montelukast intervention 3: Levocetirizine
Intervention descriptions: intervention 1: * Pharmaceutical form: Over-encapsulated tablet
* Route of administration: Oral use intervention 2: * Pharmaceutical form: Over-encapsulated tablet
* Concentration: 10 mg
* Route of administration: Oral use intervention 3: * Pharmaceutical form: Over-encapsulated tablet
* Concentration: 5 mg
* Route of administration: Oral use

Protocol document: