Conditions: Healthy
Keywords: Rotigotine Neupro® Transdermal Patch
Allocation: RANDOMIZED | Intervention model: CROSSOVER
Enrollment: 52
Healthy volunteers: yes

Brief summary:
The major aim of this study is to investigate and compare the drug amount delivered to the body after sequential application of 2 rotigotine transdermal patches from 2 different manufacturing processes.

Detailed description:

Arms:
arm 1: Two single applications of rotigotine patches from two different manufacturing processes in the order A-B separated by a washout phase of at least 5 days arm 2: Two single applications of rotigotine patches from two different manufacturing processes in the order B-A separated by a washout phase of at least 5 days

Interventions: intervention 1: Rotigotine transdermal patch
Intervention descriptions: intervention 1: Rotigotine 4.5mg/10cm\^2 patch applied for 24 hours

Protocol document: