Conditions: Locally Advanced or Metastatic Medullary Thyroid Cancer Medullary Thyroid Cancer
Keywords: Medullary Thyroid Cancer Locally advanced Metastatic Vandetanib Patient Outreach
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 205
Healthy volunteers: no

Brief summary:
The purpose of this study is to evaluate the effect of patient outreach program on the proportion of time patients with MTC experience moderate or severe AEs during first 12 months of treatment with vandetanib

Detailed description:

Arms:
arm 1: Control - treatment 300mg vandetanib opel label arm 2: Experimental - treatment 300mg vandetanib opel label

Interventions: intervention 1: Patient outreach intervention 2: Vandetanib
Intervention descriptions: intervention 1: Patients will be contacted at week 1 and then every 2 weeks until completion of 52 weeks to detect/treat AEs sooner intervention 2: Treatment 300mg vandetanib opel label.

Protocol document: