Conditions: Thyroid Cancer
Keywords: ZD6474 MTC Hereditary Medullary Thyroid Cancer Sporadic Medullary Thyroid Cancer Medullary Thyroid Cancer
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 437
Healthy volunteers: no

Brief summary:
The purpose of this study is to learn how hereditary or sporadic medullary thyroid cancer patients, treated with ZD6474, react to the drug, what happens to ZD6474 in the human body, about the side effects of ZD6474, and if ZD6474 can decrease or prevent the growth of tumors.

Detailed description:

Arms:
arm 1: Placebo vandetanib arm 2: Vandetanib

Interventions: intervention 1: ZD6474 (Vandetanib)
Intervention descriptions: intervention 1: once daily oral tablet

Protocol document: