Conditions: Anesthesia
Keywords: Anesthesia Elective surgery Propofol
Allocation: RANDOMIZED | Intervention model: PARALLEL
Enrollment: 255
Healthy volunteers: yes

Brief summary:
This is a multicenter, randomized, double-blinded, propofol-controlled, Phase 3 clinical study to evaluate the efficacy and safety of HSK3486 for induction of general anesthesia in adults undergoing elective surgery.

Detailed description:

Arms:
arm 1: HSK3486 for induction of general anesthesia. arm 2: Propofol for induction of general anesthesia.

Interventions: intervention 1: HSK3486 intervention 2: Propofol
Intervention descriptions: intervention 1: HSK3486 for induction of general anesthesia. intervention 2: Propofol for induction of general anesthesia.

Protocol document:
Prot_000.pdf: 
COVER PAGE – PROTOCOL V5.0 HSK3486-304 
 
TITLE OF STUDY: A Multicenter, Randomized, Double-blinded, Propofol-
controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of HSK3486 
Injectable Emulsion for Induction of General Anesthesia in Adults Undergoing 
Elective Surgery 
 
NCT NUMBER: NCT04711837 
 
DOCUMENT DATE: 30 JULY 2021 



















































































































































































SAP_001.pdf: 
COVER PAGE – STATISTICAL ANALYSIS PLAN 
V1.0 HSK3486-304 
 
TITLE OF STUDY: A Multicenter, Randomized, Double-blinded, Propofol-
controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of HSK3486 
Injectable Emulsion for Induction of General Anesthesia in Adults Undergoing 
Elective Surgery 
 
NCT NUMBER: NCT04711837 
 
DOCUMENT DATE: 22 NOVEMBER 2021