Please read the following table in Markdown format and then answer the question according to the table. Table cells in one row are seperated by '|', and different rows are seperated by '
'.

Table:
| No. | Name | Took Office | Left Office | President served under | Notable for |
| --- | --- | --- | --- | --- | --- |
| 1 | Harvey Washington Wiley, M.D. | January 1, 1907 | March 15, 1912 | Theodore Roosevelt, William Howard Taft | Chemist; advocacy of the passage of the Pure Food and Drug Act in 1906; subsequent work at Good Housekeeping Institute laboratories |
| 2 | Carl L. Alsberg M.D. | December 16, 1912 | July 15, 1921 | William Howard Taft, Woodrow Wilson, Warren G. Harding |  |
| 3 | Walter Gilbert Campbell | 7/16/1921 | 6/30/1924 | Warren G. Harding, Calvin Coolidge |  |
| 4 | Charles Albert Browne, Jr. | 7/1/1924 | 6/30/1927 | Calvin Coolidge |  |
| 3 | Walter Gilbert Campbell | 7/1/1927 | 4/30/1944 | Calvin Coolidge, Herbert Hoover, Franklin D. Roosevelt |  |
| 5 | Paul B. Dunbar, Ph.D. | 5/6/1944 | 5/31/1951 | Franklin D. Roosevelt, Harry S Truman |  |
| 6 | Charles W. Crawford | 6/1/1951 | 7/31/1954 | Harry S Truman, Dwight D. Eisenhower |  |
| 7 | George P. Larrick | 8/12/1954 | 12/27/1965 | Dwight D. Eisenhower, John F. Kennedy, Lyndon B. Johnson |  |
| 8 | James Lee Goddard, M.D. | 1/17/1966 | 7/1/1968 | Lyndon B. Johnson |  |
| 9 | Herbert Leonard Ley, Jr., M.D. | 7/1/1968 | 12/12/1969 | Lyndon B. Johnson, Richard M. Nixon |  |
| 10 | Charles C. Edwards, M.D. | 12/13/1969 | 3/15/1973 | Richard M. Nixon |  |
| 11 | Alexander Mackay Schmidt, M.D. | 7/20/1973 | 11/30/1976 | Richard M. Nixon, Gerald R. Ford |  |
| 12 | Donald Kennedy, Ph.D. | 4/4/1977 | 6/30/1979 | Jimmy Carter |  |
| 13 | Jere Edwin Goyan, Ph.D. | 10/21/1979 | 1/20/1981 | Jimmy Carter |  |
| 14 | Arthur Hull Hayes Jr., M.D. | 4/13/1981 | 9/11/1983 | Ronald Reagan |  |
| 15 | Frank Edward Young, M.D., Ph.D. | 7/15/1984 | 12/17/1989 | Ronald Reagan |  |
| 16 | David Aaron Kessler, M.D. | 11/8/1990 | 2/28/1997 | George H. W. Bush\nBill Clinton |  |
| 17 | Jane Ellen Henney, M.D. | 1/17/99 | 1/19/2001 | Bill Clinton |  |
| 18 | Mark Barr McClellan, M.D., Ph.D | 11/14/2002 | 3/26/2004 | George W. Bush |  |
| 19 | Lester Mills Crawford, D.V.M., Ph.D. | 7/18/2005 | 9/23/2005 | George W. Bush | Charged with conflict of interest and lying about stock he and his wife owned in companies regulated by FDA. |
| 20 | Andrew C. von Eschenbach, M.D. | 12/13/2006 | 1/20/2009 | George W. Bush | Member of the board of directors of BioTime (NYSE MKT: BTX), a biotechnology and regenerative medicine company. |
| 21 | Margaret A. Hamburg, M.D. | 5/22/2009 | present | Barack Obama |  |
Question:
how many commissioners have there been?
Answer:
21