Query: Radiomics-based Prognosis Analysis for Non-Small Cell Lung Cancer

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Feature Selection for Unsupervised Learning <=SEP=> In this paper, we identify two issues involved in developing an automated feature subset selection algorithm for unlabeled data: the need for finding the number of clusters in conjunction with feature selection, and the need for normalizing the bias of feature selection criteria with respect to dimension. We explore the feature selection problem and these issues through FSSEM (Feature Subset Selection using Expectation-Maximization (EM) clustering) and through two different performance criteria for evaluating candidate feature subsets: scatter separability and maximum likelihood. We present proofs on the dimensionality biases of these feature criteria, and present a cross-projection normalization scheme that can be applied to any criterion to ameliorate these biases. Our experiments show the need for feature selection, the need for addressing these two issues, and the effectiveness of our proposed solutions.

Machine learning: a review of classification and combining techniques <=SEP=> Supervised classification is one of the tasks most frequently carried out by so-called Intelligent Systems. Thus, a large number of techniques have been developed based on Artificial Intelligence (Logic-based techniques, Perceptron-based techniques) and Statistics (Bayesian Networks, Instance-based techniques). The goal of supervised learning is to build a concise model of the distribution of class labels in terms of predictor features. The resulting classifier is then used to assign class labels to the testing instances where the values of the predictor features are known, but the value of the class label is unknown. This paper describes various classification algorithms and the recent attempt for improving classification accuracy—ensembles of classifiers.

Radiomics: extracting more information from medical images using advanced feature analysis. <=SEP=> Solid cancers are spatially and temporally heterogeneous. This limits the use of invasive biopsy based molecular assays but gives huge potential for medical imaging, which has the ability to capture intra-tumoural heterogeneity in a non-invasive way. During the past decades, medical imaging innovations with new hardware, new imaging agents and standardised protocols, allows the field to move towards quantitative imaging. Therefore, also the development of automated and reproducible analysis methodologies to extract more information from image-based features is a requirement. Radiomics--the high-throughput extraction of large amounts of image features from radiographic images--addresses this problem and is one of the approaches that hold great promises but need further validation in multi-centric settings and in the laboratory.

Reduction Techniques for Instance-Based Learning Algorithms <=SEP=> Instance-based learning algorithms are often faced with the problem of deciding which instances to store for use during generalization. Storing too many instances can result in large memory requirements and slow execution speed, and can cause an oversensitivity to noise. This paper has two main purposes. First, it provides a survey of existing algorithms used to reduce storage requirements in instance-based learning algorithms and other exemplar-based algorithms. Second, it proposes six additional reduction algorithms called DROP1–DROP5 and DEL (three of which were first described in Wilson & Martinez, 1997c, as RT1–RT3) that can be used to remove instances from the concept description. These algorithms and 10 algorithms from the survey are compared on 31 classification tasks. Of those algorithms that provide substantial storage reduction, the DROP algorithms have the highest average generalization accuracy in these experiments, especially in the presence of uniform class noise.

Decision Tree Induction Based on Efficient Tree Restructuring <=SEP=> The ability to restructure a decision tree efficiently enables a variety of approaches to decision tree induction that would otherwise be prohibitively expensive. Two such approaches are described here, one being incremental tree induction (ITI), and the other being non-incremental tree induction using a measure of tree quality instead of test quality (DMTI). These approaches and several variants offer new computational and classifier characteristics that lend themselves to particular applications.

Automatic camera and range sensor calibration using a single shot <=SEP=> As a core robotic and vision problem, camera and range sensor calibration have been researched intensely over the last decades. However, robotic research efforts still often get heavily delayed by the requirement of setting up a calibrated system consisting of multiple cameras and range measurement units. With regard to removing this burden, we present a toolbox with web interface for fully automatic camera-to-camera and camera-to-range calibration. Our system is easy to setup and recovers intrinsic and extrinsic camera parameters as well as the transformation between cameras and range sensors within one minute. In contrast to existing calibration approaches, which often require user intervention, the proposed method is robust to varying imaging conditions, fully automatic, and easy to use since a single image and range scan proves sufficient for most calibration scenarios. Experimentally, we demonstrate that the proposed checkerboard corner detector significantly outperforms current state-of-the-art. Furthermore, the proposed camera-to-range registration method is able to discover multiple solutions in the case of ambiguities. Experiments using a variety of sensors such as grayscale and color cameras, the Kinect 3D sensor and the Velodyne HDL-64 laser scanner show the robustness of our method in different indoor and outdoor settings and under various lighting conditions.

A taxonomy for multi-agent robotics <=SEP=> A key di culty in the design of multi-agent robotic systems is the size and complexity of the space of possible designs. In order to make principled design decisions, an understanding of the many possible system con gurations is essential. To this end, we present a taxonomy that classi es multiagent systems according to communication, computational and other capabilities. We survey existing e orts involving multi-agent systems according to their positions in the taxonomy. We also present additional results concerning multi-agent systems, with the dual purposes of illustrating the usefulness of the taxonomy in simplifying discourse about robot collective properties, and also demonstrating that a collective can be demonstrably more powerful than a single unit of the collective.

A Survey of Artificial Cognitive Systems: Implications for the Autonomous Development of Mental Capabilities in Computational Agents <=SEP=> This survey presents an overview of the autonomous development of mental capabilities in computational agents. It does so based on a characterization of cognitive systems as systems which exhibit adaptive, anticipatory, and purposive goal-directed behavior. We present a broad survey of the various paradigms of cognition, addressing cognitivist (physical symbol systems) approaches, emergent systems approaches, encompassing connectionist, dynamical, and enactive systems, and also efforts to combine the two in hybrid systems. We then review several cognitive architectures drawn from these paradigms. In each of these areas, we highlight the implications and attendant problems of adopting a developmental approach, both from phylogenetic and ontogenetic points of view. We conclude with a summary of the key architectural features that systems capable of autonomous development of mental capabilities should exhibit

Design and implementation of server cluster dynamic load balancing based on OpenFlow <=SEP=> Nowadays, the Internet is flooded with huge traffic, many applications have millions users, a single server is difficult to bear a large number of clients' access, so many application providers will put several servers as a computing unit to provide support for a specific application, usually people will use distributed computing, load balancing technology to complete the work. A typical load balancing technique is to use a dedicated load balancer to forward the client requests to different servers, this technique requires dedicated hardware support, the hardware is expensive, lacks of flexibility and is easy to become a single point failure. There will be a new solution for load balancing with OpenFlow proposed., this paper mainly studies dynamic load balancing technology in the OpenFlow environment, the Controller collected the server running status through the SNMP protocol, and calculated the aggregated load of the severs according to dynamic load balancing scheduling algorithm, the OpenFlow switch will forward the client's request to the server whose aggregated load is smallest, thus minimize the response time of the web server. In the OpenFlow network environment, using this method can brings high flexibility without additional equipment.

Lexical Analysis for the Webshell Attacks <=SEP=> In this paper, we proposed a design considering for web application firewall system. Anyway, the website managing, web technology and hacker technology are vastly different from each other, whilst hacker techs are keep on moving forward, while company and government MIS are difficult of updating their information to the latest state due to working, they are often not updated and followed to the latest stuffs. And moreover, these newest techs are in generally needed to be figured out whether it matches the compatibility of the old versions, such as the recent PHP 7, many MIS are not capable to update their software to handle the variants of WAF bypass methods.

Cowden syndrome. <=SEP=> BACKGROUND
Cowden syndrome is a rare genodermatosis charactarized by presence of multiple hamartomas. The aim of the study was to specify the clinical, therapeutic and prognostic aspects of Cowden syndrome.


CASES REPORT
Our study included 4 patients with Cowden syndrome, 2 males and 2 females between 14 and 46 years old. Clinical examination of the skin revealed facials papules (4 cases), acral keratosis (1 case), translucent keratotic papules (2 cases). Oral examination revealed papules (4 cases), papillomatosis (4 cases), gingival hypertrophy (4 cases) and scrotal tongue (2 cases). Investigations revealed thyroid lesions (2 cases), fibrocystic disease and lipoma of the breast in 1 case, "glycogenic acanthosis" (1 case), macrocephaly (2 cases), dysmorphic face (1 case) and lichen nitidus (1 case). Oral etretinate and acitretine were temporary efficient in 2 patients. Topical treatment with tretinoin lotion resulted in some improvement in cutaneous, but not mucosal lesions in one patient. No cancer was revealed.


CONCLUSION
The pathognomonic mucocutaneous lesions were found in all patients. However, no degenerative lesions have been revealed. A new association of Cowden syndrome with lichen nitidus was found. Treatment with oral retinoids was efficient on cutaneous lesions.

Managing the knowledge lifecycle: A integrated knowledge management process model <=SEP=> The main purpose of this study is to propose an integrated conceptual model for exploring knowledge management process. Reviewing literature on knowledge management and tracing its historical background, definitions and dominant paradigms and analysis 32 frameworks of KM, a relatively integrated model of KM was presented in this paper. The study found many similarities of models and its presents a model which combine all the best features of the models analyzed. A 10-stage integrated model was proposed. These stages include some activities such as knowledge goal setting, identification, acquisition, creation, organization, sharing, evaluation, preservation, retention and updating and KM effectiveness evaluation. The findings can be used by managers in all organizational environments to implementation and auditing of KM practices.

A Smart Cloud Robotic System Based on Cloud Computing Services <=SEP=> In this paper, we present a smart service robotic system based on cloud computing services. The design and implementation of infrastructure, computation components and communication components are introduced. The proposed system can alleviate the complex computation and storage load of robots to cloud and provide various services to the robots. The computation components can dynamically allocate resources to the robots. The communication components allow easy access of the robots and provide flexible resource management. Furthermore, we modeled the task-scheduling problem and proposed a max-heaps algorithm. The simulation results demonstrate that the proposed algorithm minimized the overall task costs.

Tagging The Web: Building A Robust Web Tagger with Neural Network <=SEP=> In this paper, we address the problem of web-domain POS tagging using a twophase approach. The first phase learns representations that capture regularities underlying web text. The representation is integrated as features into a neural network that serves as a scorer for an easy-first POS tagger. Parameters of the neural network are trained using guided learning in the second phase. Experiment on the SANCL 2012 shared task show that our approach achieves 93.15% average tagging accuracy, which is the best accuracy reported so far on this data set, higher than those given by ensembled syntactic parsers.

A hardware CABAC encoder for HEVC <=SEP=> This paper presents a hardware design of context-based adaptive binary arithmetic coding (CABAC) for the emerging High efficiency video coding (HEVC) standard. While aiming at higher compression efficiency, the CABAC in HEVC also invests a lot of effort in the pursuit of parallelism and reducing hardware cost. Simulation results show that our design processes 1.18 bins per cycle on average. It can work at 357 MHz with 48.940K gates targeting 0.13 μm CMOS process. This processing rate can support real-time encoding for all sequences under common test conditions of HEVC standard conforming to the main profile level 6.1 of main tier or main profile level 5.1 of high tier.

Cervical Cancer Diagnosis Using Random Forest Classifier With SMOTE and Feature Reduction Techniques <=SEP=> Cervical cancer is the fourth most common malignant disease in women’s worldwide. In most cases, cervical cancer symptoms are not noticeable at its early stages. There are a lot of factors that increase the risk of developing cervical cancer like human papilloma virus, sexual transmitted diseases, and smoking. Identifying those factors and building a classification model to classify whether the cases are cervical cancer or not is a challenging research. This study aims at using cervical cancer risk factors to build classification model using Random Forest (RF) classification technique with the synthetic minority oversampling technique (SMOTE) and two feature reduction techniques recursive feature elimination and principle component analysis (PCA). Most medical data sets are often imbalanced because the number of patients is much less than the number of non-patients. Because of the imbalance of the used data set, SMOTE is used to solve this problem. The data set consists of 32 risk factors and four target variables: Hinselmann, Schiller, Cytology, and Biopsy. After comparing the results, we find that the combination of the random forest classification technique with SMOTE improve the classification performance.

Social media-induced technostress: Its impact on the job performance of it professionals and the moderating role of job characteristics <=SEP=> Using social media during work hours for non-work-related reasons is becoming commonplace. Organizations are therefore challenged with identifying and overcoming the consequences of such use. Social media-induced technostress has been identified as an important unintended consequence of using social media at work, as it could negatively impact job performance. This study draws on Person-Environment Fit to investigate the relationship between social media-induced technostress and job performance in IT professionals, and the moderating effect of job characteristics on this relationship. The results indicate that social media-induced technostress is negatively related to job performance and the negative impact of social media-induced technostress is intensified when the job characteristics are low. This work extends the literature on job-stress, social media, technostress, and job characteristics.

Mining long-term search history to improve search accuracy <=SEP=> Long-term search history contains rich information about a user's search preferences, which can be used as search context to improve retrieval performance. In this paper, we study statistical language modeling based methods to mine contextual information from long-term search history and exploit it for a more accurate estimate of the query language model. Experiments on real web search data show that the algorithms are effective in improving search accuracy for both fresh and recurring queries. The best performance is achieved when using clickthrough data of past searches that are related to the current query.

Cobalt fill for advanced interconnects <=SEP=> Cobalt as a material promises to change the conductor landscape in many areas, particularly logic contact and interconnect. In this paper, we focus on Cobalt as the conductor for logic interconnect — a potential Cu replacement. We demonstrate Co fill capability down to 10nm CD, and show that Co-Cu resistivity cross-over will occur below 14nm CD. Single damascene Co-ULK structures are used to establish an optimized metallization stack with robust CMP performance that has electromigration and TDDB reliability better than copper interconnect.

We're in it together: interpersonal management of disclosure in social network services <=SEP=> The workload needed for managing privacy and publicness in current social network services (SNSs) is placed on individuals, yet people have few means to control what others disclose about them. This paper considers SNS-users' concerns in relation to online disclosure and the ways in which they cope with these both individually and collaboratively. While previous work has focused mainly on individual coping strategies, our findings from a qualitative study with 27 participants suggest that collaborative strategies in boundary regulation are of additional importance. We present a framework of strategies for boundary regulation that informs both theoretical work and design practice related to management of disclosure in SNSs. The framework considers disclosure as an interpersonal process of boundary regulation, in which people are dependent on what others choose to disclose about them. The paper concludes by proposing design solutions supportive of collaborative and preventive strategies in boundary regulation that facilitate the management of disclosure online.

Object Detection with Active Sample Harvesting <=SEP=> The work presented in this dissertation lies in the domains of image classification, object detection, and machine learning. Whether it is training image classifiers or object detectors, the learning phase consists in finding an optimal boundary between populations of samples. In practice, all the samples are not equally important: some examples are trivially classified and do not bring much to the training, while others close to the boundary or misclassified are the ones that truly matter. Similarly, images where the samples originate from are not all rich in informative samples. However, most training procedures select samples and images uniformly or weigh them equally. The common thread of this dissertation is how to efficiently find the informative samples/images for training. Although we never consider all the possible samples “in the world”, our purpose is to select the samples in a smarter manner, without looking at all the available ones. The framework adopted in this work consists in organising the data (samples or images) in a tree to reflect the statistical regularities of the training samples, by putting “similar” samples in the same branch. Each leaf carries a sample and a weight related to the “importance” of the corresponding sample, and each internal node carries statistics about the weights below. The tree is used to select the next sample/image for training, by applying a sampling policy, and the “importance” weights are updated accordingly, to bias the sampling towards informative samples/images in future iterations. Our experiments show that, in the various applications, properly focusing on informative images or informative samples improves the learning phase by either reaching better performances faster or by reducing the training loss faster.

Behavioral resource-aware model inference <=SEP=> Software bugs often arise because of differences between what developers think their system does and what the system actually does. These differences frustrate debugging and comprehension efforts. We describe Perfume, an automated approach for inferring behavioral, resource-aware models of software systems from logs of their executions. These finite state machine models ease understanding of system behavior and resource use.
 Perfume improves on the state of the art in model inference by differentiating behaviorally similar executions that differ in resource consumption. For example, Perfume separates otherwise identical requests that hit a cache from those that miss it, which can aid understanding how the cache affects system behavior and removing cache-related bugs. A small user study demonstrates that using Perfume is more effective than using logs and another model inference tool for system comprehension. A case study on the TCP protocol demonstrates that Perfume models can help understand non-trivial protocol behavior. Perfume models capture key system properties and improve system comprehension, while being reasonably robust to noise likely to occur in real-world executions.

High-level visual features for underwater place recognition <=SEP=> This paper reports on a method to perform robust visual relocalization between temporally separated sets of underwater images gathered by a robot. The place recognition and relocalization problem is more challenging in the underwater environment mainly due to three factors: 1) changes in illumination; 2) long-term changes in the visual appearance of features because of phenomena like biofouling on man-made structures and growth or movement in natural features; and 3) low density of visually salient features for image matching. To address these challenges, a patch-based feature matching approach is proposed, which uses image segmentation and local intensity contrast to locate salient patches and HOG description to make correspondences between patches. Compared to traditional point-based features that are sensitive to dramatic appearance changes underwater, patch-based features are able to encode higher level information such as shape or structure which tends to persist across years in underwater environments. The algorithm is evaluated on real data, from multiple years, collected by a Hovering Autonomous Underwater Vehicle for ship hull inspection. Results in relocalization performance across missions from different years are compared to other traditional methods.

Increasing individual upper alpha power by neurofeedback improves cognitive performance in human subjects. <=SEP=> The hypothesis was tested of whether neurofeedback training (NFT)--applied in order to increase upper alpha but decrease theta power--is capable of increasing cognitive performance. A mental rotation task was performed before and after upper alpha and theta NFT. Only those subjects who were able to increase their upper alpha power (responders) performed better on mental rotations after NFT. Training success (extent of NFT-induced increase in upper alpha power) was positively correlated with the improvement in cognitive performance. Furthermore, the EEG of NFT responders showed a significant increase in reference upper alpha power (i.e. in a time interval preceding mental rotation). This is in line with studies showing that increased upper alpha power in a prestimulus (reference) interval is related to good cognitive performance.

The Impact of Blogging and Scaffolding on Primary School Pupils' Narrative Writing: A Case Study <=SEP=> Narrative writing is a skill that all primary (elementary) school pupils in Singapore are required to develop in their learning of the English language. However, this is an area in which not all pupils excel. This study investigates if the use of blogging and scaffolding can improve pupils’ narrative writing. Data were gathered from 36 primary five (grade five) pupils through pre-post writing tests, reflection sheets, and interviews. The pre-post writing tests were administered before and after the pupils had completed their blogging activities, while the blogs were used to draft their narrative writings and to comment on their peers’ writings. The teacher also used a writing guide that served as a scaffold to help pupils plan their writing on their blogs. Overall, results showed a statistically significant difference of medium effect size between the pre-post test scores. Pupils’ perceptions of using blogs as a tool for writing were also explored. attend school (Huffaker, 2004). In order to have success throughout life, verbal literacy is crucial and especially so from the beginnings of education to the future employment of adults (Cassell, 2004). In Singapore, the primary education system consists of a six-year program: a four-year foundation stage from primary (grade) 1 to 4 and a two-year orientation stage from primary 5 to 6 (Ministry of Education, 2010). One of the overall aims of the Singapore primary education is to give pupils a good grasp of the English Language. Literacy development such DOI: 10.4018/jwltt.2010040101 2 International Journal of Web-Based Learning and Teaching Technologies, 5(2), 1-17, April-June 2010 Copyright © 2010, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. as reading and writing is at the heart of the English Language instructional programme in Singapore schools (Curriculum Planning and Development Division (CPDD), 2001). As indicated in the 2001 English Language Syllabus

Combined software-defined network (SDN) and Internet of Things (IoT) <=SEP=> The Internet of Things (IoT) is an impending technology that captured the industries and research interests in a brief period. Presently, the number of Internet-connected devices are estimated at billions and by 2020 many studies expect to have around 50 billion devices that are connected to the Internet. The IoT devices have produced a significant amount of data that could be threatening to the security and directing the flow of data in the network. One of the alternative solutions for problems caused by IoT is to have some kind of solutions that are based on programming and primary control. Software Define Network (SDN) offers a programmable and primary control for the basic network without variability of the current architecture of the network. This paper discusses some solutions for various domains for the combined SDN based on IoT and current directions in studies. The relative analysis of these solutions prepares a simple and brief view of those directions.

Approximation Algorithms <=SEP=> There are many variations of local search: Hill-climbing: The name for the basic method described above. Metropolis: Pick a random y ∈ N(x). If f(y) < f(x), set x = y. If f(y) > f(x), set x = y with some probability. Simulated annealing: Like Metropolis, but where the probability of moving to a higher-cost neighbor decreases over time. Tabu search: Like the previous two, but with memory in order to avoid getting stuck in suboptimal regions or in plateaus (“taboo” areas). Parallel search: Do more than one search, and occasionally replace versions that are doing poorly with copies of versions that are doing well. Genetic algorithm: Keep a population of searches that changes over time via “breeding” of the best-performing searches.

Vitamins, minerals, and mood. <=SEP=> In this article, the authors explore the breadth and depth of published research linking dietary vitamins and minerals (micronutrients) to mood. Since the 1920s, there have been many studies on individual vitamins (especially B vitamins and Vitamins C, D, and E), minerals (calcium, chromium, iron, magnesium, zinc, and selenium), and vitamin-like compounds (choline). Recent investigations with multi-ingredient formulas are especially promising. However, without a reasonable conceptual framework for understanding mechanisms by which micronutrients might influence mood, the published literature is too readily dismissed. Consequently, 4 explanatory models are presented, suggesting that mood symptoms may be expressions of inborn errors of metabolism, manifestations of deficient methylation reactions, alterations of gene expression by nutrient deficiency, and/or long-latency deficiency diseases. These models provide possible explanations for why micronutrient supplementation could ameliorate some mental symptoms.

NameClarifier: A Visual Analytics System for Author Name Disambiguation <=SEP=> In this paper, we present a novel visual analytics system called NameClarifier to interactively disambiguate author names in publications by keeping humans in the loop. Specifically, NameClarifier quantifies and visualizes the similarities between ambiguous names and those that have been confirmed in digital libraries. The similarities are calculated using three key factors, namely, co-authorships, publication venues, and temporal information. Our system estimates all possible allocations, and then provides visual cues to users to help them validate every ambiguous case. By looping users in the disambiguation process, our system can achieve more reliable results than general data mining models for highly ambiguous cases. In addition, once an ambiguous case is resolved, the result is instantly added back to our system and serves as additional cues for all the remaining unidentified names. In this way, we open up the black box in traditional disambiguation processes, and help intuitively and comprehensively explain why the corresponding classifications should hold. We conducted two use cases and an expert review to demonstrate the effectiveness of NameClarifier.

LegUp: high-level synthesis for FPGA-based processor/accelerator systems <=SEP=> In this paper, we introduce a new open source high-level synthesis tool called LegUp that allows software techniques to be used for hardware design. LegUp accepts a standard C program as input and automatically compiles the program to a hybrid architecture containing an FPGA-based MIPS soft processor and custom hardware accelerators that communicate through a standard bus interface. Results show that the tool produces hardware solutions of comparable quality to a commercial high-level synthesis tool.