Query: External Knowledge and Query Strategies in Active Learning: a Study in Clinical Information Extraction

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2010 i2b2/VA challenge on concepts, assertions, and relations in clinical text <=SEP=> The 2010 i2b2/VA Workshop on Natural Language Processing Challenges for Clinical Records presented three tasks: a concept extraction task focused on the extraction of medical concepts from patient reports; an assertion classification task focused on assigning assertion types for medical problem concepts; and a relation classification task focused on assigning relation types that hold between medical problems, tests, and treatments. i2b2 and the VA provided an annotated reference standard corpus for the three tasks. Using this reference standard, 22 systems were developed for concept extraction, 21 for assertion classification, and 16 for relation classification. These systems showed that machine learning approaches could be augmented with rule-based systems to determine concepts, assertions, and relations. Depending on the task, the rule-based systems can either provide input for machine learning or post-process the output of machine learning. Ensembles of classifiers, information from unlabeled data, and external knowledge sources can help when the training data are inadequate.

Heterogenous Uncertainty Sampling for Supervised Learning <=SEP=> Uncertainty sampling methods iteratively request class labels for training instances whose classes are uncertain despite the previous labeled instances. These methods can greatly reduce the number of instances that an expert need label. One problem with this approach is that the classifier best suited for an application may be too expensive to train or use during the selection of instances. We test the use of one classifier (a highly efficient probabilistic one) to select examples for training another (the C4.5 rule induction program). Despite being chosen by this heterogeneous approach, the uncertainty samples yielded classifiers with lower error rates than random samples ten times larger.

Application of information technology: MedEx: a medication information extraction system for clinical narratives <=SEP=> Medication information is one of the most important types of clinical data in electronic medical records. It is critical for healthcare safety and quality, as well as for clinical research that uses electronic medical record data. However, medication data are often recorded in clinical notes as free-text. As such, they are not accessible to other computerized applications that rely on coded data. We describe a new natural language processing system (MedEx), which extracts medication information from clinical notes. MedEx was initially developed using discharge summaries. An evaluation using a data set of 50 discharge summaries showed it performed well on identifying not only drug names (F-measure 93.2%), but also signature information, such as strength, route, and frequency, with F-measures of 94.5%, 93.9%, and 96.0% respectively. We then applied MedEx unchanged to outpatient clinic visit notes. It performed similarly with F-measures over 90% on a set of 25 clinic visit notes.

Effective mapping of biomedical text to the UMLS Metathesaurus: the MetaMap program <=SEP=> The UMLS Metathesaurus, the largest thesaurus in the biomedical domain, provides a representation of biomedical knowledge consisting of concepts classified by semantic type and both hierarchical and non-hierarchical relationships among the concepts. This knowledge has proved useful for many applications including decision support systems, management of patient records, information retrieval (IR) and data mining. Gaining effective access to the knowledge is critical to the success of these applications. This paper describes MetaMap, a program developed at the National Library of Medicine (NLM) to map biomedical text to the Metathesaurus or, equivalently, to discover Metathesaurus concepts referred to in text. MetaMap uses a knowledge intensive approach based on symbolic, natural language processing (NLP) and computational linguistic techniques. Besides being applied for both IR and data mining applications, MetaMap is one of the foundations of NLM's Indexing Initiative System which is being applied to both semi-automatic and fully automatic indexing of the biomedical literature at the library.

Information-Based Objective Functions for Active Data Selection <=SEP=> Learning can be made more efficient if we can actively select particularly salient data points. Within a Bayesian learning framework, objective functions are discussed that measure the expected informativeness of candidate measurements. Three alternative specifications of what we want to gain information about lead to three different criteria for data selection. All these criteria depend on the assumption that the hypothesis space is correct, which may prove to be their main weakness.

The PhysIO Toolbox for Modeling Physiological Noise in fMRI Data <=SEP=> BACKGROUND
Physiological noise is one of the major confounds for fMRI. A common class of correction methods model noise from peripheral measures, such as ECGs or pneumatic belts. However, physiological noise correction has not emerged as a standard preprocessing step for fMRI data yet due to: (1) the varying data quality of physiological recordings, (2) non-standardized peripheral data formats and (3) the lack of full automatization of processing and modeling physiology, required for large-cohort studies.


NEW METHODS
We introduce the PhysIO Toolbox for preprocessing of physiological recordings and model-based noise correction. It implements a variety of noise models, such as RETROICOR, respiratory volume per time and heart rate variability responses (RVT/HRV). The toolbox covers all intermediate steps - from flexible read-in of data formats to GLM regressor/contrast creation - without any manual intervention.


RESULTS
We demonstrate the workflow of the toolbox and its functionality for datasets from different vendors, recording devices, field strengths and subject populations. Automatization of physiological noise correction and performance evaluation are reported in a group study (N=35).


COMPARISON WITH EXISTING METHODS
The PhysIO Toolbox reproduces physiological noise patterns and correction efficacy of previously implemented noise models. It increases modeling robustness by outperforming vendor-provided peak detection methods for physiological cycles. Finally, the toolbox offers an integrated framework with full automatization, including performance monitoring, and flexibility with respect to the input data.


CONCLUSIONS
Through its platform-independent Matlab implementation, open-source distribution, and modular structure, the PhysIO Toolbox renders physiological noise correction an accessible preprocessing step for fMRI data.

Eratosthenes sieve based key-frame extraction technique for event summarization in videos <=SEP=> The rapid growth of video data demands both effective and efficient video summarization methods so that users are empowered to quickly browse and comprehend a large amount of video content. It is a herculean task to manage access to video content in real time where humongous amount of audiovisual recorded data is generated every second. In this paper we propose an Eratosthenes Sieve based key-frame extraction approach for video summarization (VS) which can work better for real-time applications. Here, Eratosthenes Sieve is used to generate sets of all Prime number frames and nonprime number frames up to total N frames of a video. k-means clustering procedure is employed on these sets to extract the key–frames quickly. Here, the challenge is to find the optimal set of clusters, achieved by employing Davies-Bouldin Index (DBI). DBI a cluster validation technique which allows users with free parameter based VS approach to choose the desired number of key-frames without incurring additional computational costs. Moreover, our proposed approach includes likes of both local and global perspective videos. The method strongly enhances clustering procedure performance trough engagement of Eratosthenes Sieve. Qualitative and quantitative evaluation and complexity computation are done in order to compare the performances of the proposed model and state-of-the-art models. Experimental results on two benchmark datasets with various types of videos exhibit that the proposed methods outperform the state-of-the-art models on F-measure.

Quantifying the total wetted surface area of the world fleet: a first step in determining the potential extent of ships’ biofouling <=SEP=> Ships’ hulls can transport aquatic nuisance species, but there is little quantitative information about the magnitude of vessel biofouling on a global or regional scale. There does not exist a robust method to estimate the wetted surface area (WSA) of a particular fleet of ships, especially across the diversity of possible vessel types. An estimate of the total WSA of ship arrivals into a port or region is essential to determine the potential scope of biofouling and to inform management strategies to reduce the future invasions. Multiple statistical models were developed so commonly available ships’ parameters could be used to estimate the WSA for a given set of fleet data. Using individual ship characteristics and publicly available data from  ~120,000 active commercial ships in the world fleet, the method results in a total global minimum WSA estimate of approximately 325 × 106 m2. The size of the global fleet employed here is greater than the commonly cited vessel number of approximately 80,000–90,000, as we include ships <100 gross tons. Over 190,000 vessels were initially identified, representing a WSA of 571 × 106 m2, but active status of only 120,000 vessels could be confirmed. Reliable data were unavailable on the operating status of many additional and especially smaller vessels. This approach, along with a contemporary and comprehensive estimate of global WSA, when combined with knowledge of the different operational profiles of ships that may reduce biofouling (port residence times, steaming speeds, extent of antifouling coatings, cleaning frequency, etc.), can inform current numerical models and risk assessments of bioinvasions.

Documenting Software Architectures: Views and Beyond <=SEP=> * This author is with the Software Engineering Institute at Carnegie Mellon University. ** This author is with the School of Computer Science at Carnegie Mellon University. Software architecture has emerged as a foundational concept for the successful development of large, complex systems. Signs that the field is maturing to become an engineering discipline include textbooks on the subject; the work in repeatable design, exemplified by architectural styles and patterns; robust methods for evaluating software architectures; international conferences devoted to it; and recognition of architecture as a professional practice. However, treatment of architecture to date has largely concentrated on its design, and to a lesser extent, its validation. But effectively documenting an architecture is as important as crafting it, because if the architecture is not understood (or worse, misunderstood) it cannot meet its goals as the unifying vision for system and software development. Three years ago, researchers at the Software Engineering Institute and the Carnegie Mellon School of Computer Science set out to answer the question: “How should you document an architecture so that others can successfully use it, maintain it, and build a system from it?” The result of that work is an approach we loosely call “views and beyond.” [1] Modern software architecture practice embraces the concept of architectural views. A view is a representation of a set of system elements and relations associated with them. Modern systems are more than complex enough to make it difficult to grasp them all at once. Instead, we restrict our attention at any one moment to one (or a small number) of the software system’s structures, which we represent as views. Some authors prescribe a fixed set of views with which to engineer and communicate an architecture. Rational’s Unified Process, for example, is based on Kruchten’s 4+1 view approach to software [4]. The Siemens Four Views model [3] is another example. A recent trend, however, is to recognize that architects should produce whatever views are useful for the system at hand. IEEE 1471 exemplifies this philosophy; it holds that an architecture description consists of a set of views, each of which conforms to a viewpoint, which in turn is a realization of the concerns of one or more stakeholders. This philosophy about views leads to the fundamental principle of the views-and-beyond approach:

VeTrack: Real Time Vehicle Tracking in Uninstrumented Indoor Environments <=SEP=> Although location awareness and turn-by-turn instructions are prevalent outdoors due to GPS, we are back into the darkness in uninstrumented indoor environments such as underground parking structures. We get confused, disoriented when driving in these mazes, and frequently forget where we parked, ending up circling back and forth upon return.In this paper, we propose VeTrack, a smartphone-only system that tracks the vehicle's location in real time using the phone's inertial sensors. It does not require any environment instrumentation or cloud backend. It uses a novel "shadow" tracing method to accurately estimate the vehicle's trajectories despite arbitrary phone/vehicle poses and frequent disturbances. We develop algorithms in a Sequential Monte Carlo framework to represent vehicle states probabilistically, and harness constraints by the garage map and detected landmarks to robustly infer the vehicle location. We also find landmark (e.g., speed bumps, turns) recognition methods reliable against noises, disturbances from bumpy rides and even hand-held movements. We implement a highly efficient prototype and conduct extensive experiments in multiple parking structures of different sizes and structures, with multiple vehicles and drivers. We find that VeTrack can estimate the vehicle's real time location with almost negligible latency, with error of 2-4 parking spaces at 80-percentile.

Prediction and Simulation of Human Mobility Following Natural Disasters <=SEP=> In recent decades, the frequency and intensity of natural disasters has increased significantly, and this trend is expected to continue. Therefore, understanding and predicting human behavior and mobility during a disaster will play a vital role in planning effective humanitarian relief, disaster management, and long-term societal reconstruction. However, such research is very difficult to perform owing to the uniqueness of various disasters and the unavailability of reliable and large-scale human mobility data. In this study, we collect big and heterogeneous data (e.g., GPS records of 1.6 million users1 over 3 years, data on earthquakes that have occurred in Japan over 4 years, news report data, and transportation network data) to study human mobility following natural disasters. An empirical analysis is conducted to explore the basic laws governing human mobility following disasters, and an effective human mobility model is developed to predict and simulate population movements. The experimental results demonstrate the efficiency of our model, and they suggest that human mobility following disasters can be significantly more predictable and be more easily simulated than previously thought.

Connecting Language and Knowledge Bases with Embedding Models for Relation Extraction <=SEP=> This paper proposes a novel approach for relation extraction from free text which is trained to jointly use information from the text and from existing knowledge. Our model is based on two scoring functions that operate by learning low-dimensional embeddings of words and of entities and relationships from a knowledge base. We empirically show on New York Times articles aligned with Freebase relations that our approach is able to efficiently use the extra information provided by a large subset of Freebase data (4M entities, 23k relationships) to improve over existing methods that rely on text features alone.

Clarithromycin and Tetracycline Binding to Soil Humic Acid in the Absence and Presence of Calcium. <=SEP=> Numerous ionizable organic micropollutants contain positively charged moieties at pH values typical of environmental systems. Describing organic cation and zwitterion interaction with dissolved natural organic matter requires explicit consideration of the pH-dependent speciation of both sorbate and sorbent. We studied the pH-, ionic strength-, and concentration-dependent binding of relatively large, organic cations and zwitterions (viz., the antibiotics clarithromycin and tetracycline) to dissolved humic acid in the absence and presence of Ca(2+) and evaluated the ability of the NICA-Donnan model to describe the data. Clarithromycin interaction with dissolved humic acid was well described by the model including the competitive effect of Ca(2+) on clarithromycin binding over a wide range of solution conditions by considering only the binding of the cationic species to low proton-affinity sites in humic acid. Tetracycline possesses multiple ionizable moieties and forms complexes with Ca(2+). An excellent fit to experimental data was achieved by considering tetracycline cation interaction with both low and high proton-affinity sites of humic acid and zwitterion interaction with high proton-affinity sites. In contrast to clarithromycin, tetracycline binding to humic acid increased in the presence of Ca(2+), especially under alkaline conditions. Model calculations indicate that this increase is due to electrostatic interaction of positively charged tetracycline-Ca complexes with humic acid rather than due to the formation of ternary complexes, except at very low TC concentrations.

Survey of clustering algorithms for MANET <=SEP=> Many clustering schemes have been proposed for ad hoc networks. A systematic classification of these clustering schemes enables one to better understand and make improvements. In mobile ad hoc networks, the movement of the network nodes may quickly change the topology resulting in the increase of the overhead message in topology maintenance. Protocols try to keep the number of nodes in a cluster around a pre-defined threshold to facilitate the optimal operation of the medium access control protocol. The clusterhead election is invoked on-demand, and is aimed to reduce the computation and communication costs. A large variety of approaches for ad hoc clustering have been developed by researchers which focus on different performance metrics. This paper presents a survey of different clustering schemes.

Maximum energy harvesting from medium voltage electric-field energy using power line insulators <=SEP=> One essential requirement for a modern Smart Grid is continuous monitoring of the grid variables. This task is efficiently achieved using self-powered electronic devices deployed throughout the grid network. Within the vicinity of the grid power lines, the high voltages of these lines can provide a source of energy for such loads using capacitive coupling. This is known as Electric-Field Energy Harvesting (EFEH). However, the reported strategies that use this principle have not explored how to maximise their power transfer, which is essential for practical systems since the available energy from EFEH is invariably quite small. In this paper, a novel approach for optimum energy harvesting is proposed using the parasitic capacitance of medium-voltage power line insulators. A follow-on power electronic conversion system is then used to maintain the load conditions that maximise the extracted energy. The system performance has been analysed using theoretical studies and computer simulations to identify the operating conditions that maximise the extracted energy. Results obtained so far suggest that up to 100 mW can be harvested from 22 kV grid feeders, using only the capacitive coupling that exists between the line insulator harvester and the feeder conductor.

Efficient reinforcement learning using Gaussian processes <=SEP=> IX

Learning Sparsely Used Overcomplete Dictionaries <=SEP=> We consider the problem of learning sparsely used overcomplete dictionaries, where each observation is a sparse combination of elements from an unknown overcomplete dictionary. We establish exact recovery when the dictionary elements are mutually incoherent. Our method consists of a clustering-based initialization step, which provides an approximate estimate of the true dictionary with guaranteed accuracy. This estimate is then refined via an iterative algorithm with the following alternating steps: 1) estimation of the dictionary coefficients for each observation through l1 minimization, given the dictionary estimate, and 2) estimation of the dictionary elements through least squares, given the coefficient estimates. We establish that, under a set of sufficient conditions, our method converges at a linear rate to the true dictionary as well as the true coefficients for each observation.

Fuzzy controlled fast charging system for lithium-ion batteries <=SEP=> A DSP is adopted to construct a fuzzy controlled lithium-ion battery charging system. By using this intelligent charging system, the data collection, calculation and peripheral circuit control are performed for the battery charging status. According to the lithium-ion battery charging specifications, two hours are required for battery charging. A fuzzy logic controller (FLC) is constructed by using the battery protection cell voltage and voltage difference among the batteries. They are used as the input variable to shorten the charging and equalizing time and assure that the battery will be operated within the safety voltage range.

A Particle Swarm Optimization ( PSO )-based Heuristic for Scheduling Work fl ow Applications in Cloud Computing Environments <=SEP=> Cloud computing environments facilitate applications by providing virtualized resources that can be provisioned dynamically. However, users are charged on a pay-per-use basis. User applications may incur large data retrieval and execution costs when they are scheduled taking into account only the ‘execution time’. In addition to optimizing execution time, the cost arising from data transfers between resources as well as execution costs must also be taken into account. In this paper, we present a particle swarm optimization (PSO) based scheduling heuristic for data intensive applications that takes into account both computation cost and data transmission cost. We experiment with a workflow application by varying its computation and communication costs. We analyze the cost savings when using PSO as compared to using existing ‘Best Resource Selection’ (BRS) algorithm. Our results show that we can achieve: a) as much as 3 times cost savings as compared to BRS, b) good distribution of workload onto resources, when using PSO based scheduling heuristic.

3D Face Recognition Using Shapes of Facial Curves <=SEP=> Recognition of human beings using shapes of their full facial surfaces is a difficult problem. Our approach is to approximate a facial surface using a collection of (closed) facial curves, and to compare surfaces by comparing their corresponding curves. The differences between shapes of curves are quantified using lengths of geodesic paths between them on a pre-defined curve shape space. The metric for comparing facial surfaces is a composition of the metric involving individual facial curves. These ideas are demonstrated in the context of face recognition using the nearest-neighbor classifier

Community-Affiliation Graph Model for Overlapping Network Community Detection <=SEP=> One of the main organizing principles in real-world networks is that of network communities, where sets of nodes organize into densely linked clusters. Communities in networks often overlap as nodes can belong to multiple communities at once. Identifying such overlapping communities is crucial for the understanding the structure as well as the function of real-world networks. Even though community structure in networks has been widely studied in the past, practically all research makes an implicit assumption that overlaps between communities are less densely connected than the non-overlapping parts themselves. Here we validate this assumption on 6 large scale social, collaboration and information networks where nodes explicitly state their community memberships. By examining such ground-truth communities we find that the community overlaps are more densely connected than the non-overlapping parts, which is in sharp contrast to the conventional wisdom that community overlaps are more sparsely connected than the communities themselves. Practically all existing community detection methods fail to detect communities with dense overlaps. We propose Community-Affiliation Graph Model, a model-based community detection method that builds on bipartite node-community affiliation networks. Our method successfully captures overlapping, non-overlapping as well as hierarchically nested communities, and identifies relevant communities more accurately than the state-of-the-art methods in networks ranging from biological to social and information networks.

The head direction signal: origins and sensory-motor integration. <=SEP=> Navigation first requires accurate perception of one's spatial orientation within the environment, which consists of knowledge about location and directional heading. Cells within several limbic system areas of the mammalian brain discharge allocentrically as a function of the animal's directional heading, independent of the animal's location and ongoing behavior. These cells are referred to as head direction (HD) cells and are believed to encode the animal's perceived directional heading with respect to its environment. Although HD cells are found in several areas, the principal circuit for generating this signal originates in the dorsal tegmental nucleus and projects serially, with some reciprocal connections, to the lateral mammillary nucleus --> anterodorsal thalamus --> PoS, and terminates in the entorhinal cortex. HD cells receive multimodal information about landmarks and self-generated movements. Vestibular information appears critical for generating the directional signal, but motor/proprioceptive and landmark information are important for updating it.

A hybrid method for imputation of missing values using optimized fuzzy c-means with support vector regression and a genetic algorithm <=SEP=> Missing values in datasets should be extracted from the datasets or should be estimated before they are used for classification, association rules or clustering in the preprocessing stage of data mining. In this study, we utilize a fuzzy c-means clustering hybrid approach that combines support vector regression and a genetic algorithm. In this method, the fuzzy clustering parameters, cluster size and weighting factor are optimized and missing values are estimated. The proposed novel hybrid method yields sufficient and sensible imputation performance results. The results are compared with those of fuzzy c-means genetic algorithm imputation, support vector regression genetic algorithm imputation and zero imputation. 2013 Elsevier Inc. All rights reserved.

Task driven perceptual organization for extraction of rooftop polygons <=SEP=> A new method for extracting planar polygonal rooftops in monocular aerial imagery is proposed. Structural features are extracted and hierarchically related using perceptual grouping techniques. Top-down feature veri cation is used so that features, and links between the features, are veri ed with local information in the image and weighed in a graph. Cycles in the graph correspond to possible building rooftop hypotheses. Virtual features are hypothesized for the perceptual completion of partially occluded rooftops. Extraction of the \best" grouping of features into a building rooftop hypothesis is posed as a graph search problem. The maximally weighted, independent set of cycles in the graph is extracted as the nal set of roof

Didn't you see my message?: predicting attentiveness to mobile instant messages <=SEP=> Mobile instant messaging (e.g., via SMS or WhatsApp) often goes along with an expectation of high attentiveness, i.e., that the receiver will notice and read the message within a few minutes. Hence, existing instant messaging services for mobile phones share indicators of availability, such as the last time the user has been online. However, in this paper we not only provide evidence that these cues create social pressure, but that they are also weak predictors of attentiveness. As remedy, we propose to share a machine-computed prediction of whether the user will view a message within the next few minutes or not. For two weeks, we collected behavioral data from 24 users of mobile instant messaging services. By the means of machine-learning techniques, we identified that simple features extracted from the phone, such as the user's interaction with the notification center, the screen activity, the proximity sensor, and the ringer mode, are strong predictors of how quickly the user will attend to the messages. With seven automatically selected features our model predicts whether a phone user will view a message within a few minutes with 70.6% accuracy and a precision for fast attendance of 81.2%

Conjugated linoleic acid and disease prevention: a review of current knowledge. <=SEP=> Conjugated linoleic acid (CLA), a derivative of a fatty acid linoleic acid (LA), has been reported to decrease tumorigenesis in animals. CLA is unique because unlike most antioxidants which are components of plant products, it is present in food from animal sources such as dairy foods and meats. CLA concentrations in dairy products typically range from 2.9 to 8.92 mg/g fat of which the 9-cis, 11-trans isomer makes up to 73% to 93% of the total CLA. Low concentrations of CLA are found in human blood and tissues. In vitro results suggest that CLA is cytotoxic to MCF-7 cells and it inhibits the proliferation of human malignant melanoma and colorectal cancer cells. In animal studies, CLA has inhibited the development of mouse epidermal tumors, mouse forestomach cancer and rat mammary cancer. Hamsters fed CLA collectively had significantly reduced levels of plasma total cholesterol, non-high-density lipoprotein cholesterol, (combined very-low and low-density lipoprotein) and triglycerides with no effect on high-density lipoprotein cholesterol, as compared to controls. Dietary CLA modulated certain aspects of the immune defense but had no obvious effect on the growth of an established, aggressive mammary tumor in mice. It is now thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. There is, however, insufficient evidence from human epidemiological data, and very few of the animal studies have shown a dose-response relationship with the quantity of CLA feed and the extent of tumor growth. Further research with tumor models is needed to test the efficacy and utility of CLA in cancer and other disease prevention and form the basis of evaluating its effect in humans by observational studies and clinical trials.

Gore Galore: Literary Theory and Computer Games <=SEP=> Computer games have not been adequately theorized within the humanities. In this paper a brief history of computer games is presented as a starting point for developing a topology of games and a theory of computer games as rhetorical artifacts suitable for critical study. The paper addresses the question of why games should be treated seriously and suggests a theoretical approach based on Backhtin’s poetics of the novel where the experience of time and space (the chronotope) provides a framework of questions for discussing computer games.

Qualitative Methods in Research on Teaching <=SEP=> This chapter reviews basic issues of theory and method in approaches to research on teaching that are alternatively called ethnographic, qualitative, participant observational, case study, symbolic interactionist, phenomenological, constructivist, or interpretive. These approaches are all slightly different, but each bears strong family resemblance to the others. The set of related approaches is relatively new in the field of research on teaching. The approaches have emerged as significant in the decade of the 1960s in England and in the 1970s in the United States, Australia, New Zealand, and Germany. Because interest in these approaches is so recent, the previous editions of the Handbook of Research on Teaching do not contain a chapter devoted to participant observational research. Accordingly, this chapter attempts to describe r~s and their theoretical _nresup~s in considerable detail and does not attempt an exhaustive review of the rapidly growing literature in the field. Such a review will be appropriate for the next edition of this handbook. From this point on I will use the term interpretive to refer to the whole family of approaches to participant observational research. I adopt this term for three reasons: (a) It is more inclusive than many of the others (e.g., ethnography, case study); (b) W Blake

Breast disorders in pregnant and lactating women. <=SEP=> The breast undergoes extensive changes during pregnancy and lactation that can create diagnostic challenges. This article reviews the anatomy of the breast, breast changes associated with pregnancy and lactation, and breast imaging techniques for pregnant and lactating women. Various benign breast conditions in this patient population also are discussed, such as lactating adenomas, galactoceles, and granulomatous mastitis. Finally, pregnancy-associated breast cancer is presented, including its epidemiology, diagnosis, staging, treatment, and prognosis.

A traffic-aware street lighting scheme for Smart Cities using autonomous networked sensors <=SEP=> Street lighting is a ubiquitous utility, but sustaining its operation presents a heavy financial and environmental burden. Many schemes have been proposed which selectively dim lights to improve energy efficiency, but little consideration has been given to the usefulness of the resultant street lighting system. This paper proposes a real-time adaptive lighting scheme, which detects the presence of vehicles and pedestrians and dynamically adjusts their brightness to the optimal level. This improves the energy efficiency of street lighting and its usefulness; a streetlight utility model is presented to evaluate this. The proposed scheme is simulated using an environment modelling a road network, its users, and a networked communication system and considers a real streetlight topology from a residential area. The proposed scheme achieves similar or improved utility to existing schemes, while consuming as little as 1-2% of the energy required by conventional and state-of-the-art techniques.