Year: 1859

new puucture will become !red, a vesicle form
| rapidly, and overtake the FIRST pock.


The fact of an arm becoming sore," is not
sufficient evidence, as the same might result
from the use of dull, dirty lancet, or any r-
ritating matter is capable of producing q
philgmanous pustule, which might deceive the
uniformed The vesicle should begin to form
on the fifth day after the virus has been insert
ed, and begin to decline on the eleventh. 1t
should have silvery or pearly appearance,
umbilicated or pitted on the top small scab
forms in the pit and gradually spreads over the
surface, during the decline of the disease the
crust should be about one-third of an inch in
diameter and of mahogany color when it
drops of, which is about the end OF the third,
or during the fourth week From the eighth
day TO the tenth, the constitution generally
sympathises with the local affection and a
slight tever is present, which soon disappears.
The slightest deviation from the regular pro-
greSs and appearance of the vaccine vesicle,
should he sufficient cause for doubt in the mind
Of the Physician as to the efficiency of the
vaccination and the completeness of the pro-
lection afforded by it.


1t was favorite theory with Jenner, that
" when the system has once been perfectly and
completely under the vaccine influence, to
point of saturation, it remains forever after
secure from yariolous contagion."


Observation has shown that during epidem-
les of smallpox, many who had been previous
ly vaccinated suffered with the disease, more
or less modified This gave origin to the idea
that the vaccine disease, though once secure
and complete, would run out" And some
have tried to FIX the exact time. Seven years
has been suggested, on the theory that the
system was renewed every seven years, bot
this hypothesis is groundless, as more recent
observation has shown concusively that the
same change takes place every four days and
FIVE hours. Perhaps the age of puberty may
have something to do with it.


The theory of DR.. Jenner seems to be well
founded, as abundance OF proof will show
The fault lies in the virus used, the manner in
which il is used, and the accidents occurring
during the progress of the vesicIe Vaccine
virus may become so deteriorsted in q few
weeks. as to deceive the PhySican-eyen that
which is fresh and pure from the COW, unless
protected from the atmosphere, heat and mois
ture Vrus becomes less active in proportion
to the number of constitutions it passes
through If this be true, may it not become
inert? =? The virus partakes of the nature Of
the disease In the system through which il
passes, hence the virus becomes unfit for use
after passing through constitutions of scrofu-
lous habit, or herpetic or other cutaneous dis
eases it should only be taken from healthy
subjects.


Certain individuals are insusceptible TO the
vaccine disease, from some peculiar idiosyncrasy
-sGch probably would resist the yariolous
con,agou. In view of these facts, it is proper
to recommend revaccination after puberty
This will guarantee to the patient complete
security from that most pestilental disease, so
much dreaded 10y all the human family.


Respectfully submitted.


GEo. II. MORGAN, NJ. D., Chm.