skysight-inc/HackerNews huggingface dataset:
A couple of problems:

1. It's not allowed in most residential areas.

2. If you hit rock, you need new tools. (AKA explosives.)

3. If you hit water, you need new tools. (And it's unsatisfying to have mud wash right into the whole you've been digging.)

4. If you want a roof, you need new tools.

5. If you have to fill your hole back in, it's hard and unrewarding work.

6. You will be pitch black and smell like crap. And your washing machine won't be able to handle it. And you need to bathe vigorously.

7. If you live in a place where you can freely dig, there's probably nobody to show your work off to.
In my naive mind, I think it might be sustainable.

(During the past week I paid for the first month of private github hosting on my personal CC for the company I work for. Will get it re-imbursed and transition it to some company CC when I get the time.)
Users in the past had every opportunity to think and learn, and their failure to do so is why we are where we are today. I mean, there are still people who refuse to wear seatbelts or vaccinate their children... How can we ever expect people to understand all the moving parts in a secure computer system?
"Cultural fit" is just another form of discrimination, a currently legal alternative to racism, sexism, and other forms of illegal discrimination in the US to keep the "unliked" and "unwanted" out of jobs. The author acknowledges this, yet still sees fit to add advice for using cultural fit; that weakens the article a bit, but not much.

The reality is "cultural fit" should never be used to make decisions. It is never right, either as a predictor of performance or ethically. Companies and interviewers already have an incredibly difficult time figuring out ways in which to judge qualifications, even when standard tests and procedures are available. To add in this nonsensical idea of "cultural fit," something that can't be measured, quantified, qualified, or identified, and to make that a selection criteria for applicants not only shirks the duty to hire the most qualified, but gives the company and interviewers an unchallengeable way to reject applicants, an option that otherwise would--and should--be illegal.

tldr: Cultural fit is discrimination, it cannot predict job performance or any otherwise meaningful information related to a candidate's skills and abilities, and should be illegal as its only use is to deny qualified applicants jobs they qualify for.
This. Cortisol is the enemy, so anything you can do to bring down the cortisol will help decrease that tired feeling after 8 hours of work. That means doing three things programmers aren't well known for: eating well ("close to the farm" as my grandfather put it), exercising and sleeping at night. Vitamin C and Omega-3 are supplements that supposedly help with reducing cortisol in the short term.
It is human nature to want to escape. In Mexico, for instance, escapees who do not break any other laws are not charged for anything and no extra time is added to their sentence.

https://en.wikipedia.org/wiki/Prison_escape#Punishment
AFAIK skyr is no yogurt, it is a quark.

https://en.wikipedia.org/wiki/Quark_%28dairy_product%29
Caldero Murciano – Rice Stew with Fish, Murcia Style
Face It, Your Brain Is a Computer
Not to mention a single mistake can be ruinous, requiring absolute perfection 100% of the time (from users and programmers).

One can hope that, eventually, formally mathematically verified open source systems will help solve the issue, at least on the programming side.
I had the same question but even if there is no real functional difference, a product can compete on less tangible factors. The market is full of competing products that all do pretty much the same thing. What are the real and important differences between gmail and fastmail or any other major webmail provider? Yet each has users who prefer that platform. There's room for more than one time picking service.

As many here will point out, there are very few really new ideas in apps.
I hate the hobbies question in interviews. I work 60 hours a week and have a toddler. My hobby is sleeping. What the hell else else do you want from me?
Not the same. In 1960s people couldn't send around links to videos of exploding NASA rockets.

Following will have vastly different effects
1) Seeing a video footage once a life time
2) Seeing a footage (even edited for added entertainment) over and over again whenever you want

I'm glad NASA wasn't trying to develop rockets in the age of Facebook and youtube.
> In practice sites get hacked, fail to enforce HTTPS, databases get leaked, etc.

Exactly. The threat here is that a single SuperGenPass-generated site-specific is leaked somehow (if you use it for a lot of sites, one of them is bound to be storing a password in plaintext, or not using https, or whatever–or, for all I know, the OP is such an important target maybe someone specifically sets up a website to capture a sample site-specific password). Then, using that site-specific password, a determined attacker might be able to recover your master password and then be able to login to all the other websites you use SuperGenPass with. That's the danger of using a 'fast' hash function to generate your site-specific password.
Schizophrenic, psychotic, psychopathic (antisocial), autistic, ADHD.
Thank you for illustrating what is wrong with "culture fit". There is no need to require candidates to be buds with the team. " maturity" "Professionalism" used to be a virtue that adults aspired to, until young adults decided to hack the system and turn the "Good ol' boys" club into a "good youn' boys" club.
This does not solve the two issues I have with doodle:

- The creator is the only person with permission to add alternatives (both for their "Make a choice" and "Find a date" features)

- There's no way to limit the number of responses from each participant - e.g. each user need to select their 3 most preferred time slots.

Also this app, contrary to Doodle, requires you to select time slots, whilst with Doodle one can just decide on dates (and the time is optional). I also quite like the "Yes/No/If-needbe" feature that Doodle provides and I'm disappointed about the binary view of event planning this application takes.
To follow up, the papers can sometimes be deliberately vague with respect to actual volumes/masses/materials, as theoretically the concentration, & activity and other state-functions sufficiently describe the system. The exact DNA sequence I use might be important, but if I just say I used gene, 'hGENE1', that should be sufficient for the published science. Sure, my hGene1 might have a mutation, or yours might, but we'd never learn that if we just kept passing around the same plasmid, calling it hGene1 (I'm looking at you, cell-lines...).

That you used brand-X tubes should generally not be important to the science (conceptually, though sometimes they are physically), and so should be left out of the paper's protocol precisely so that another lab does not use that tube during a replication study. It's not bad science that using brand-X tube yields different results than brand-Y tube, though it can be frustrating to learn that is the crux of the difference you've been seeing. It is precisely that kind of variable that must be ferreted out, and can often only be ferreted out when labs attack the same problem from a different angle.
Can you imagine if ICANN were a private company?

We could see insane gTLDs like .book and .diamond owned by large multi-national corporations.

Oh wait...
I was once let go from a company for "just not being a good fit" after landing them a successful contract with bigTechCo here in the bay area and earning them over $1mm in services.

Further, they had showed me that my bonus was going to be over $27K one three separate occasions, then they let me go before having to pay me the bonus because I had to be actually employed there to receive my share of the money earned from me doing 100% of the work.

People should not be able to be fired for "not being a good fit" they should have concrete documented issues on which to fire someone.
Hey, thanks for linking to my PasswordMaker app! :) I saw this linked on /r/programming earlier and mentioned it there.

I'm not sure how the password counter and "customizable password policy" (I'm assuming this refers to the password templating feature?) make Master Password more flexible, though. PasswordMaker offers plenty of configuration options you can tweak when you want to change the password for a site; I've begun creating multiple profiles as sites varying in their password requirements. I use the Chrome extension you linked to, as well, which auto-selects the profile based on the URL I'm browsing.
> If the registry cannot be trusted, SSL kinda goes out the window anyway

You seem to have gotten things backwards. If the DNS is hijacked, SSL is the only thing protecting a visitor from being lured into the hijacked site.

Connecting these two things into one makes SSL effectively worthless.
Who's the Most Innovative Flight Search Engine?
Greece debt crisis: Eurozone refuses bailout extension
Yes, I think overall it might even be better for education. Tons of 18-year-old college students have no idea what they want out of college or how to achieve it. That might also be true of 24-year-olds, but I would guess a larger % by that point have a better idea why they are attending college, what they want to study, and how to study it.
The specifics of the animals used for example may be the cause of severe errors and cause wildly different results.
One such approach would be to use Sterling coolers, which (IIRC) is one of the suggested approaches for surface activities on Venus. Standard refrigeration techniques should also work reasonably well.

Also, why wouldn't standard heat-dumping work well in a CO2 atmosphere? If anything, it should work better; the vacuum of space is the best insulator known to man, so literally anything else would be better for heat dissipation.
Looking at this through the lens of drug discovery is the wrong way to do this. The problem is with our drug discovery strategy, generally, not with the reproducibility of our research.

STK33, for example, is definitely implicated in cancer through a wide variety of mechanisms. It is often mutated in tumors, and multiple studies have picked it up as having a role in driving migration, metastasis, etc.

This doesn't mean we can make good drugs to it.

Making drugs is hard - they need to be available in the tissue in the right concentrations, often difficult to achieve with a weird-shaped, sticky molecule. They need to have specificity for the tumor, they need to have specificity for the gene target(s) of interest. They need to be effective at modulating the target.

More importantly, though, the drug is modulating a target (gene) that is involved in a biological system that involves complex systems of feedback control, produces adaptive responses, and otherwise behaves in unexpected ways in response to modulation.

In my experience this is usually underappreciated by most drug discovery strategies, which merely seek to "inhibit the target" as if its involvement in the tumor process means we can simply treat it as an "on-off" switch for cancer. This assumption is asinine, and of course will (and does) lead to frequent failure. STK33 is not an on-off switch, and attempting to treat it that way will likely result in a drug that does nothing.
Nice story, especially about the company's beginnings.

I encourage people to try their hand at making yogurt. It's a little time consuming (proper prep, timing, temperature monitoring, cleanup), but otherwise easy and the result is so satisfying. For me, the cost is about the same (if using expensive milk at 2x the price of "normal" stuff), but again it's all about satisfaction.

It's partly about the value of understanding one's food, and partly that with only a little practice, it's difficult to find better tasting yogurt at the store.
It looks like the site is down due to traffic.
Ok, so you don't have to physically move you data to the cloud, it can reside locally and just be queried on demand, right?
Ask HN: Why are Web Components not more popular?
A couple years ago Web Components were supposed to be the big new thing, but since then there has been very little adoption in the real-world. Why is that?
Succeeding in the chinese tech market, if you play by the government's rules
I've never experienced that from people that don't drink--whatever their reason--but even if I did, I'd prefer it to working with alcoholics and companies that encourage alcoholism. Out of more than a dozen or so places in SF and Silicon Valley I've worked, every single one had booze on premises except for one. One company even had booze on premises despite its parent company explicitly forbidding it (they were fully owned at the time). This bias against people who don't drink is quite great and has even led me and others to have a drink from time to time just to fit in or try to land a job. It's stupidity like this that could be avoided if "cultural fit," "attitude," and other bullshit, unquantifiable, unrelated to job performance reasons of judgement were made illegal like blatant discrimination already is.
Not the OP, but Death is a cruel mistress. Sometimes even a 40 year old will outlive quite a few friends. I'm 44 and about a 1/3 of my graduating high school class of 20 are gone. Of the friends I made in college about 1/3 moved and I didn't keep in touch, and a couple of other died. I never married (that billionaire comment tomcam feels a bit too true sometimes).

I have plenty of relatives along with close friends (enough that getting together to play Arkham Horror is becoming a logistic nightmare), but I could easily, with just a few unlucky breaks or moves, not have any close friends. It isn't even that uncommon.
This is a nicely consumable lightweight summary of how the node event loop works. In my experience this is one of the hardest things for new JS developers to actually understand, especially those coming to the language with a limited asynchronous programming background. Here's a good link to how the browser event loop works for those interested: http://blog.carbonfive.com/2013/10/27/the-javascript-event-l...

IMHO, there's just a few things you need to understand to start getting productive with js fast, #1 on the list is to know how the event loop in the browser/node works and this is a really good intro to the node side of things. #2 is event bubbling/capturing in the DOM (http://javascript.info/tutorial/bubbling-and-capturing), and #3 would be everything about functions / function scoping.

Those are the parts I always try to explain first to devs I've mentored who were just jumping in to javascript.
Yes, it's the truth of the biological knowledge that is most important. And we get at that best not by replicating a particular experimental design in two labs, but by examining it in the context of a diversity of different experiments with different assumptions.

The Reproducibility Project is run by people in the business of replicating experimental design for profit. They argue that a proportion of public research money should be given to businesses like theirs for this process. This will take a lot of resources that would otherwise be spent examining biological knowledge from different angles rather than the same angle multiple times. In the end, we will know less.
How to Win Friends and Influence People, by Dale Carnegie. I've found that killing 'em with kindness often produces much better results.
Here's what it looks like, since the website is down. http://www.moddb.com/engines/tilengine

This is actually a great idea if I understand it correctly: An engine built for modern platforms that emulates the limitations, gfx modes, emulates the sound engine of the NES/GBA, etc. without limiting CPU/video memory or CPU speed. I imagine it could be reimplemented as a subset of libSDL.
What are the levels used in US municipal fluoridation?
Jsperf.com brought down by flood of spam
It also casts a doubt on the independence of the verification. It will only catch outright cases of falsification, but innocent situations where the procedure is erroneous or the conclusions are wrongly drawn will slip through.

If the reproducers don't quite know what they are doing if left to their own devices, they will invariably be influenced by the original researchers into being blind to exactly the same mistakes and making the same wrong inferences.

Another software analogy: it's like QA people needing detailed hand-holding from the original developer in testing some program, instead of independently looking for ways to break it. That is then no better than the original functional testing by the developer.
That may be true, but one of the key ideals in science is that the findings are reproduceable. If I can't reproduce it, it's helpful for the science to be fairly specific, in case the findings depended on details that were thought to be unimportant, but we later find out were critical. The most interesting science comes in unexpected results.

I feel it's like a piece of closed source software releasing "the source code" and yet no one can make it compile. You don't have to have a clean codebase, it can be a bit tricky to build, but it has to be able to be compiled before anyone can have any confidence in your claims. If you don't provide that, it's much less useful.

The separate issues of for profit labs and what support they should expect in this context are tough issues, but we shouldn't undermine the science to thwart them.
> So your preference is for fundamental changes to the institution of marriage to be propagated by the force of state power rather than through reason, persuasion, and organic change.

Of course not. But that is, sadly, not an option. The forces of ignorance and bigotry are too deeply entrenched in the U.S. That is one of the costs of freedom. People are free to be ignorant, and they are free to be bigots. But the government -- neither federal nor state -- does not have that freedom, thank God.

> I'm afraid the Union Army wasn't fighting for gay rights,

No, they were fighting for the union. But then, having won the war and established the nation as a sovereign power, when the fourteenth amendment was duly enacted it became binding on all the states. Sometimes when you fight for things you end up accomplishing more than you set out to do.
It's okay, most apps don't bother checking certificate validity anyway.
In part of the USA, the tradition of churches tending to the flock is still going strong. Also, the local gathering place where folks swap news and talk (the bakery in the small town I'm in) is still a fixture.
> it's about smoking out unfit candidates [ ... ]

> The skills and expertise of a candidate have to be pretty convincing for me to overlook the fundamentalism part and the troubles that they might bring onboard.

You're aware that discriminating based on religion is illegal, right? Not just "oh, that's not very nice, let's not do that" or "hey, it would be cool to build a world with more tolerance for X", but literally, "the law of the United States prohibits us from discriminating against a person due to this". (And if you're in another country, substitute your country, and the law is likely similar.)

For the record, I'm not religious at all. I'm a pretty reasonable guy in general and I subscribe to rational thought and give folks the benefit of the doubt where I can.

But I'm going to take a hard line here. You're doing something that's really fucked up, and you show a basic lack of respect for other human beings by insisting they fall in line with your way of thought (alcohol and religion both, in this case, but your comment history makes me even sadder), and you show a basic lack of respect for the way we have set up society to let people live their lives the way they want.

If you're ever involved in a hiring decision, please go kindly fuck yourself.
This is absolutely correct. Pharma companies are running into a wall and are flailing to figure out what to do. It's quite clear that from first principles bathing the entire body in trillions of little molecules hoping that they only and completely shut down a single kind of protein, at the right time, in the right place, of the right cell, and do nothing more, is insane. There is some logic behind the ability for a small molecule to help against invading diseases (the antibiotics of the 20th century), but the same strategy will philosophically not work for entire classes of cancers or other innate biological problems. Though we all somehow just assumed that it would.

The pharmacy of the future will be entirely curative to non-invading diseases, will repair the DNA that's been mutated, will express or inhibit the proteins that need to be expressed or inhibited. And small molecules will be the payload of these fancy protein-based nano-machines. But this hunt to bring down the cost of those small-molecule targets at the cost of the reputation of the science itself might be foolhardy when the cost is near-infinite in the first place because they're looking from the wrong perspective.

tldr; Pharmaceutical companies' hammer that worked so well against the nails of bacterial infection is in no way suited to the plumbing of cancer. And now they're 'investigating the plumbers' to figure out why their fancy new 50-billion-dollar "water-hammers" don't work so well to unclog pipes.
That's called religious discrimination and no, we don't have to forgive you for it.
I manage a small open source project (https://github.com/frappe/erpnext) that churns 100+k per year and helps me manage a small team. It took me 4-5 years to reach here. We make money by providing hosting and also help to other developers working on our platform.

I would start with a services plan and a beautiful website. If you are not a designer, do hire one. Good design and quality can go a very long way towards achieving your dream.

If your project is an app, you can also go the SAAS (softare-as-a-service) way. But beware, building a multi-tenant platform, and working on user onboarding, marketing your site can be 2x to 3x of your original project your project.

The good thing is that once you are there, 1/2 years is a reasonable time, this will only grow.
I have used this mechanism manually with a simple algorithm and a secret key + site name for a while... And all of the things you mention are exactly on point :)

My solution has been to have 3 different techniques:

- a very sofisticated master password + algorithm for very critical things
- a secondary, less sofisticated for less important things
- a dummy password that i use for silly stuff

I keep an up to date list of applications of the second tier. The first tier is easy enough to remember since it's the critical apps.

I also go with 2fa when I can.
Is a big ego crucial to achieving sporting greatness?
My criticism was only of the justification given. And honestly, the attitude in scientific publishing has never been "science should be written so that people in industry can reproduce the results at minimal effort/expense and without acquiring scientists who know the area and techniques well."

(Also, your post would have worked just as well without the first sentence.)
I think "desire for automation" is in the right direction, but doesn't quite hit the mark. For me, it's more like "not wanting to solve the same problem twice". I don't really care if it's automated or not, but once I've solved a problem I don't want to think about it again (unless there's some new twist).

At my last job I was always getting bugged by support people asking me the same questions over and over. So I wrote documentation/guides telling how to solve the common issues.

TL;DR: it's not so much "robots are awesome" as "ain't nobody got time for that!".
I am currently reading a couple of materials in order to fully understand lower C. Looks like we should correspond, my email is in my profile.Interest area: web server and compilers.
how homeless set up a company

you mean immigrate to UK?
This entire soap opera is tiring. I don't even understand why it is in HN frontpage other than as a curiosity.