skysight-inc/HackerNews huggingface dataset:
If you're talking about engineered longevity and you're not talking about the brace of technologies that fall under the SENS umbrella [1], or even the Hallmarks of Aging catalog [2] then you're missing the most important part of the field. All of the meaningful advances of the future are going to emerge from repair of the causes of aging, not from tinkering with the operation of metabolism to try to recapture some fraction of the benefits of calorie restriction. Or even, hell, five times the benefit of calorie restriction. That won't move the needle far in humans. You'll be a lot healthier, but still die on much the same schedule as your parents and grandparents.

It costs two billion dollars or more to push through one drug candidate for a given desired effect. Current estimates suggest you could implement the entire SENS program of rejuvenation treatments in mice for that amount of money over 10 years. Those are technologies with potentially unbound gains on healthy life span; not just slowing down aging, but actually reversing its causes. Periodic repair has no limit on the degree to which it can extend life, and is far more effective for old people than merely slowing aging. Given the options here I know what I'd rather see the research community focusing on, but getting more R&D to focus on repair over metabolic tinkering is an ongoing process of persuasion and disruption.

You might look at senescent cell clearance for an example of a SENS technology that is slowly breaking into mainstream research notice. Oh so slowly. It's almost painful to watch so much time and effort being directed to old-style mine the natural world drug discovery for marginal treatments unlikely to move the needle when we're in the midst of a biotechnology revolution and so much more is possible.

[1]: http://sens.org/research/introduction-to-sens-research

[2]: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836174/
Can you elaborate a bit more please?

This sounds almost as if you configured a network adapter to only send and not receive, but you used "optics", so I'm guessing you refer to some sort of fibre-based device that actually impedes light to go in the other direction, and thus the security is via physical means?
Show HN: Use the same distance field for raymarching and collision
My dad claims that the level of brainwashing in Russia far far exceeds that of the Soviet regime, and the propaganda is by far worse (and worse than WWII Germany he says).

Of course statements like that evoke Godwin's law and a hard to swallow. However, my dad grew up in Soviet Russia and trained troops on the use of artillery equipment during the Soviet Afghanistan conflict. He's been around the block and has seen firsthand the Soviet propaganda in multiple Soviet republics.

If you think about the insidiousness of troll-style, FUD propaganda, it's way way more psychologically insidious than the overt Soviet propaganda. You can't cut off access to facts and appear "fair"--instead you make people question the truth.

Russia just raised a whole young generation that's a socially-backwards by a generation. Homophobic, racist, blame-the-west feelings are rampant.

During the early days of the Ukranian conflict, I was surprised to hear a close relative in Russia tell me how she has seen videos on Youtube of "blacks from Africa" killing innocent Russian youths ("gouging their eyes out" she said) in Eastern Ukraine.

This shit is real.
You know, it's things like these that set back the notion of an open, anonymous and free internet.
Unmarried 30-something here, no kids.

When I made 100K, my monthly expenses were ~$3000, but I took home about $5000, which left me with a little over 2K in savings each month. The #1 expense is rent (SF Bay Area is bad), followed by food (I eat out for lunch every day, and I don't cook often in my shitty apartment).

One thing to consider is that $1 is $1 anywhere in the country. Consider the following scenario:

50K salary = 37K take-home pay - 50% expenses (keep the math simple) = ~18K savings

100K salary = 65k take-home-pay - 50% expenses = ~32K savings

In my experience, even though the cost of living is higher, the salary-to-expenses ratio is roughly the same (give or take a few K). In other words, even if I have to pay $2500/mo for my 1BR apartment in San Francisco, and my monthly expenses reach $4000, I'm still saving at least $1000/mo, which is more than I'd be able to save making a comparable salary (~40K) back home in Alabama.
"Why don't people seem to use the F keys?"

Probably because that doesn't fit well with touch typing. A great thing about vim is that you can do everything as a touch typist, without reaching for the outlying districts of the keyboard (assuming you've remapped the escape key to capslock, or learned to use ^[, or mapped it).
At GitHub we take a fairly manual approach to migrations, basically the migration is done in its own PR ahead of the PR that has the code.
What BitKeeper Got Wrong? (2005)
It doesn't sound like a bug, just a legitimate difference in how things are done. In any case, CPU-specific optimizations are hardly rare.
That's how much he's saving. He just answered the question posted in the title.
Armored Door Can't Protect Twin Brother Hackers from Russian Cops
This is great. One thing the author should do is remap enter to something better than "jump to end of file." I remapped mine to ":w<CR>" to save the current file, and it's stuck.
The Inside Story on How SurveyMonkey Cracked the International Market
How can that ever work? If you're using TCP/IP, you always need to receive an acknowledgement that what you sent actually got to the destination, right?

Or does raw fiber use different protocols?
The rest of the world has also gotten much better at propaganda. Listing to older broadcasts can almost seem laughable in comparison.

EX: Reefer madness vs. modern anti-smoking campaigns. http://en.wikipedia.org/wiki/Reefer_Madness http://www.usatoday.com/story/news/nation/2014/06/24/cdc-smo...

I find it deeply concerning how easily a modern state can alter how its population thinks. Outright lies are a lot easier to counter than selective truths.
It's interesting to me how entitled the employees come across as. Minecraft was making millions, but they were only getting a regular salary. (Aside from luxury trips to Monaco with their families, and an extremely laid back and pleasant work environment.)

I remember that Notch was doing Minecraft development all alone for the longest time, even after it had become hugely popular, and users had been begging him to hire people to speed up development. So these employees join as regular employees, getting a regular salary, taking none of the risks of the founders, yet they are pissed off because they don't own shares of the company.

I suspect this is very common in successful startups, and in a way I understand it: They see the founders, guys their age, rolling in the dough, on the back of their work. I've felt the same way as an employee, when stuff I come up with and implement ends up making the company a lot of money and the most I get, if I'm lucky, is a pat on the back.

But, as a founder? Where the fuck do you get off expecting to take a piece of my company, that I have literally sacrificed blood, sweat and tears for, taken time away from my life and my family, risked huge amounts of money, relationships and years of my life, without any guarantee that I would ever succeed. And you take an interview, walk in the door from nine to five and do your job, which you get fairly compensated for, and would not be paid anymore for anywhere else, you can, and probably will, leave whenever you feel like it with no stress or loss. Yet because the company succeeds, somehow you are entitled to own parts of it for simply being there and doing your job?
> In this state, the activities of their customers are completely legal

No, they aren't. Federal law is applicable in every state, and activities illegal under federal law are illegal in every state. It may not be prohibited by state law in that state, but then neither is, probably, espionage (of, e.g., US defense information) prohibited by the law of that state. That doesn't make espionage legal in that state, and doesn't mean that someone advertising software specifically designed and marketed for the purpose of supporting such espionage wouldn't have significant legal risks.

> Regardless of where you stand on marijuana (I am not a partaker) they have a fascinating story working to legitimize a once illegal market.

Its not "a once illegal market" anywhere in the US. Everywhere in the US, its a still illegal market, its just the number of separate authorities prohibiting it is one fewer in some jurisdictions than it used to be in some places.
I completely agree with you. Trying to find a drug that can affect the complex molecular machinery in just the right way is likely not going to work. A more likely outcome is that we will find a drug that can treat a certain age-related disease by working on these pathways.
I was at a security trade show earlier this year and some companies were marketing "FTP diode": one way FTP transfert.

I did not have time to discuss it with them, but how a tcp based protocol could be "one way" just does not make sense to me...
I have no problem with competition nor open research, which is probably how the researchers viewed this competition. My problem was how strikingly small the reward was for custom tailoring months of their efforts and research towards helping a single company eliminate hundreds of thousands of jobs and save billions of dollars. The top prize wasn't even enough budget for a lab assistant for a year! It sounds more like an evil plot from a sinister villain than it does an interesting research opportunity. If you want to do interesting research, don't let multinational companies with obvious agendas tell you what is interesting unless they are also willing to share the reward that they get from your hard work.
Hey Patrick, slight off-topic: Any plans to support Georgia (the country in Europe)?
Right. You'd also want a soft limit. Your regular diagnostics would notice the counter was over the soft limit and turn on the equivalent of a 'check engine' light.
Wikipedia says that's around the average Russian wage.
You are certain that trolls derailed the conversation?

It could just as well be one person stating his opinions. His opinions are controversal, and therefore they generate lots of responses (derailing) and he is downvoted because they go against what most people here believe. Doesn't quite seem like an army of professional "trolls" manipulating the discussion (If he is a troll, he would probably have presented his statements more effectively or subtly. The way he did almost guaranteed being downvoted).

Those "troll groups" are surely not a good thing, and you can never be certain this person wasn't one of them, but I also wouldn't label everyone I don't agree with a troll, just because they dare to write down their opinion, and my point of view is the one of the majority.
The Ministry of Truth in the making.
>The FBI asked the AP not to disclose the names of the fake companies it uncovered, saying that would saddle taxpayers with the expense of creating new cover companies to shield the government’s involvement, and could endanger the planes and integrity of the surveillance missions. The AP declined the FBI’s request because the companies’ names – as well as common addresses linked to the Justice Department – are listed on public documents and in government databases.

Glad to see AP still has gumption.
> When it was imagined, we called it "distopian"

I always though it was "dystopian" but your spelling made me check again. Apparently, "distopia" is used in some romance languages like

Spanish - http://es.wikipedia.org/wiki/Distop%C3%ADa

Portuguese - http://pt.wikipedia.org/wiki/Distopia

Italian - http://it.wikipedia.org/wiki/Distopia
The article is talking about the stated politics fueled goal of eradicating extreme poverty as defined by the world bank. Not the definition from wikipedia.

It's not arguing against eradicating absolute poverty - it's saying that the current discussion is just politics and not helpful.
That's awesome! Seems like a really solid setup. Bufferapp took a page from your book and have the same deploy setup with hubot... it works out really well for them, too.

I have three questions to ask about DB migrations (which I can guess the answers to but would love to hear directly), if that's okay:

How do you handle a DB migration with a staged rollout (two 2 of N production servers)?

How do you organise timing between a migration deploy and code deploy if one is done before the other?

How do you handle rollbacks?
Except this post has given the impression that they are being over zealous in who they deem 'risky,' for whatever reason. If others could share similar 'over zealous' stories from other financial providers I might reconsider.
I've always found the social issues surrounding extending life to be chilling after reading Kurt Vonnegut's take on it in "Tomorrow and Tomorrow and Tomorrow" (http://en.wikipedia.org/wiki/Tomorrow_and_Tomorrow_and_Tomor...). What would a future look like where there is very little room for young people to grow?
if we find a way of turning an endeavor like this into producing economic value, and if we manage to convince capitalists to see the long-term benefits of sustainability, we can, for once, really disrupt.

way to go, VCs
The new mac minis (Late 2014) are terrible (google and see), and are not useable for anything other than web browsing. I recently had to dump this new mac mini and switch to a Macbook Pro for mac/iOS dev as they severely underpowered and limited entry level mac-minis, not to mention the craziness of soldering the ram (when form factor isn't an issue, compare to previous models), making basic upgrades impossible.

In conclusion, running Yosemite on VMs, especially AMD is really hard, and not worth it in the long run. Buy a mac instead, but AVOID the latest mac minis and get some other non-crippled model.
Given how they had the researcher effectively locked up in a hotel room with strict security measures, I'd say it's because they're terrified of corporate espionage and suchlike.
We need this out as soon as possible. I personally think so because then we will manufacture less alkaline based batteries and save the environment. Also then things will be more efficient. We as people should protect this invention against the big company giants. Who will definitely try to kill it.

I request you all to get it out there and make the best of it.

Mr. Bob Roohparvar

I STAND BY HERE IN THIS AMAZING INVENTION'S PROGRESS
> so I'm guessing you refer to some sort of fibre-based device that actually impedes light to go in the other direction, and thus the security is via physical means?

Correct. To simplify, imagine a diode on one side and a photodetector cell on the other. On a microcontroller, this would be an opto-isolator (http://en.wikipedia.org/wiki/Opto-isolator).

Of course, the higher levels of the OSI protocol you're using need to support this sort of physical layer. Its typically used on very primitive, low-bitrate connections (sensors mostly, although I've seen it used in highly sensitive installations using scada equipment).

Bruce Schneier has a great piece on air gaps. I've included a link to it below.

https://www.schneier.com/blog/archives/2013/10/air_gaps.html
Your zipcode is more important than your genes in determining your health
It's also spreading lies about Russians to non-Russians. See for example The Guardian online forums - these guys dominate conversations which have something do to with Putin's policies (say the Crimea situation etc).
Have you tried fugitive (a vim wrapper around git)?
How do you end up with 9 copies of everything? I'm not sure I follow that.

If you are passing in massive ArrayList<Integer> lists to external libraries, you need to re-evaluate what you're doing. What will that external library do with this?
The "bad guys" can rate things too :)
It's VISA and MC that are the problem, not Stripe, they are simply operating under terms dictated to them by the card companies and the feds.

If you want to make money with something legally grey don't point the finger at companies who are in a tight spot when it comes to dependencies on such entities. Credit card processing is not an in-alienable right.
Itg_flat theme for VIM
The GP probably means an opto-isolater.

It obviously wouldn't work for carrying something like TCP/IP but rather much lower level signaling.

http://en.m.wikipedia.org/wiki/Opto-isolator
Who is actually building these barracks-style accommodations for minimum wage workers?

That is something that occurred in the early days of industrialization, and still occurs in factory towns in newly industrializing economies, but not in the contemporary US. Where everyone is expected to finance a car and a single-family detached house.
Yes. They are called analogues and these laws were created ostensibly in response to the trend of "designer drugs" being developed to evade their scheduling as illegal drugs, by staying ahead of the schedules.

There was a crackdown in smoke-shops in New York on the weed-not-weed "synthetic marijuana" and "functional analogues" of cannabis. For a while you could go into any hookah lounge or corner smoke shop, see a case on the counter with 1g and 2g silver-colored ziplock bags, or 5-10g jars... ask for some "incense" or read whatever it says on the bag out loud (and don't say "spice" because K2/spice had already been scheduled).

You'd receive a bag of something that looks like weed, with labels clearly indicating it was not to be marked or marketed for human consumption, that it was a novelty item and definitely not safe, but if you tried it and you actually knew what marijuana was but for some reason couldn't get any real bud, you'd probably agree it was a passable substitute.

Then these shops all started getting visits from the state police, and you couldn't buy them anymore. Their whole inventory would be seized, under the new (at the time) Federal Analog Act.

I hear you can still get salvia and kratom, but I also heard those are both really not anything like cannabis, other than both being organic and having pharmaceutical applications, that you really couldn't easily use either of those and be at all confused about whether it was pot or not.
Input Type Sandbox
100% agree with you..
Maybe it's a variation of TFTP (which uses UDP) that doesn't ack the connection or the file? That would be rather amusing, broken TFTP sold as a security app.
Or at least give each user the option and default it to unshared. I don't see why they'd default to sharing everyone's.
If you think that is disturbing then you should wonder how the rest of the world feels whenever America decides that its local laws should be applied in foreign countries.
Open sourcing it is nice and all from an idealist standpoint, but given the complexity of the software (millions of LOC), the fact that all the software would be used in commercial companies, and simply the area itself (cars), do you really think the community would pick up on it? I doubt it. Plus, the researcher did audit it - 18-20 months' work, and that was just analyzing it, not actually improving or fixing it.

Plus there is no car manufacturer ever that would allow anyone to change the firmware on their own.
The security of such a thing assumes that:

1) The system can't be compromised through input data.

2) There's no other output mechanism by which an attacker could retrieve data (or watch the plane crash, which technically counts as output).

I'm not sure I buy the idea for contexts where a genuine security airgap is required.
Air Traffic CISO draws on Facebook to revamp corporate security culture
But is that remote DMA? Controller/driver-managed DMA transfers in the fashion of "shovel the next X incoming kilobytes to this memory range" is not the same as arbitrary writes to host memory initiated by a device.
You specifically said 'in any capacity', I quoted that to make sure there was no mis-understanding about what I was referring to, I understand the particulars of this case.
I know in some places they rely heavily on pay-by-phone services as a credit card alternative, even for face-to-face transactions. The cost of whatever they're buying gets subtracted from their phone credits and the phone company passes the money on to the actual business. I'm not sure how one would go about integrating this as a payment option for a phone app though, or if it's possible to do this without violating the Google Play agreements.
It provides a predictable rate of flow into the terminal.
Most people in poverty don't have a choice on how their lives might play out. As I understand it, they're often quite ignorant and helpless to improve their lot. Or they're bonded servants, or slaves. It's very sad, there's no way out, no possible route up and out. This world is so often a hell for its denizens.

I suppose that's why others are reacting so strongly to you. You're latching onto some odd hobo hipster ideal - but reality does not come close to your ideal.
Sorry, the “No Managers” Trend at Startups Is Bullshit
This is the Achilles heel of the entire Internet of Things and smart appliance trend, and I think this will bite everyone bad. After 50+% of these vendors go out of business in the next decade, their products won't get updated, and people will wonder why their "smart" TV can't watch movies from whatever replaced Netflix/new whizbang video service. They won't be as likely to buy any "smart" thing again.
There is a huge cadence mismatch between software cycles and capital good replacement cycles.

How well would you say that Tesla is coping with this as a company? For that matter, what about Apple?

I can't even imagine the number of security patches that have gone into the Linux kernel in the last 11 years.

Let's take a step back and think about this statement. Isn't this insane? We know enough to be able to build something much better than this. The reason that we don't, is that we've just kept on pragmatically building on what we had before. We're like a corporation that keeps pouring money into its "stovepipe" system because we keep on making short-term decisions. (Somehow "stovepipe" has come to mean "vertically isolated," but I seem to remember that it also used to refer to the tendency of iron stovepipes to corrode and need constant patching.)
What's wrong with humor on HN? I think it is perfectly fine.
Considering the ridiculous amount of testing required (rightly so) for any change on the jetliners, they probably cannot keep up with the patches.

One Windows running company I worked for long time ago simply didn't apply the patches. They said it broke things...
You're right, TCP/IP wouldn't work. UDP would work fine though, as well as anything lower level. You'd just continually send packets at a rate that was slow enough that there'd be no reason that the other side would drop them.

Imagine that the designers want to send information about the plane's expected arrival time to the in-flight entertainment system. You could send a packet once per minute, without any knowledge of whether or not anyone is even listening. If an update is missed, it doesn't matter since the information rapidly becomes stale.
UK companies relocating over Snooper's Charter anti-encryption surveillance law
Believe it or not, guys from cities do marry girls from countryside. Men from higher socioeconomic status marrying down is both socially acceptable and practical in Today's China.
* 1) Apple was the first to use USB even though it wasn't an Apple tech

Not actually true. USB was shipping on PC motherboards for about a year before Apple went whole hog on USB. At the time, however, almost no one actually used USB (I think the first primary use of USB was keyboards and mice, and the first generation of USB keyboards and mice were notably inferior to their PS2 equivalents). Once Apple backed USB, other companies started to do the same.