skysight-inc/HackerNews huggingface dataset:
These are the CDR chains -

CDR1 comprising GFAFNYYDM/I/LH (SEQ ID NO:1)
CDR2 comprising YINPGGGNTYYADSV (SEQ ID NO:2);
CDR3 comprising QLYGNSFMDY (SEQ ID NO:3),

or

a heavy chain CDR3 comprising QLYGNSFFDY (SEQ ID NO:4),
a heavy chain CDR1 comprising SEQ ID NO:1 or GFAFNYYDMF (SEQ ID NO:17),
and a heavy chain CDR2 comprising SEQ ID NO:2, and

a light chain sequence, comprising a light chain CDR1, CDR2 and CDR3, wherein the light chain CDR3 comprises HYSTPLT (SEQ ID NO:5).
Its true that Rustbox uses C code right now. Its just a wrapper around the original termbox library. My goal for rustbox is to be a full Rust port of termbox, removing the reliance on C. Hadn't heard of busybox, will check it out. Thanks!
There are lot of factors which are discussed but not considered when it came to concluding this topic.

The increase in population : Instead of comparing the ratio or the percentage of working vs non-working with the present population it compares x out of every 100.

The increase in jobs : 2000 vs 2014, the number of jobs available has also changed which is not taken in account. As mentioned in the article older people end up creating more jobs.

The increase in unemployment rate : Yes, this contradicts with the above mentioned increase in jobs point but this should also be a factor. This also is affected by people not-from US who work in US.

The Shift in Generation : 14 years brings/builds a very different minded person and this person might have a different approach to living.

The higher standard of living : This also is one of the reasons why older people are still working and won't leave their jobs as their value is appreciated, helps pay the debt and they could satisfy all their needs to live a life of luxury(?) and fulfil all their ambitions.
> The most likely culprit is processed food […]

Processed food alone does not seem to explain all data (though you do mention “plastics contain hormone-like chemicals”):

- Mammals that live near or with humans, from lab rats to pet pooches, have gotten fatter over recent decades.

- Fatter lab animals are the hardest to explain, since their diet is tightly controlled and well documented.

Source: http://news.discovery.com/animals/fat-pets-obesity-weight.ht...
Repository of censored and sensitive Chinese keywords
> SLA's are never free from anyone

This 1000x. SLAs are not free. Your time is not free. Nothing is free.

No agency is doing ongoing support for free.

Either a.) the potential customer is negotiating hard, or b.) the other companies have included this expense already in the main bid and have bounded the max hours they will provide support.
JAVA iOS tools
I thought this was pretty interesting (http://www.heavens-above.com/IssHeight.aspx?) The mean height of the ISS over a two year period.

I had no idea that atmospheric drag had that great an effect at a 400km altitude.
Well I was going to deride the article because they're bragging about a medical finding that still only works in mice models. These often don't carry over into human beings.

But other than that, always nice to see progress made against wasting diseases and aging.
It is great that you are able to do this, but not that your situation is not the one described in the article. The article discusses men who only qualify for low/no skill jobs paying $10-15/hr. That is markedly different from a tech startup cofounder who could get a software engineering job paying $100k+ with benefits.
300 bytes per second. And you pay per minute of conection time rather than data amount.

In my mind The iridium network is cool, but a bit to outdated for anything other than phone conversations and stuff like remote sensors like Weather buoys.

I am looking at the near future when it comes to "consumer" satelite communication, there is some stuff there.
The also lured/poached some UI folks from Apple [1] to work on it.

You think risk-averse Ford would attract the same talent as a hot-as-shit disruptor with a large upside stock potential and the chance to "redefine the world"?

[1] http://9to5mac.com/2014/07/29/much-of-teslas-ui-design-team-...
Every metropolitan region in the US needs to elect a modern tribune.

http://en.wikipedia.org/wiki/Tribune_of_the_Plebs

A modern tribune should play both the role of sheriff and prosecutor. The powers of a tribune should be constrained to act for the people against government agencies. To that end, they would have power to arrest and detain government officials, convene grand juries, and prosecute trials.

To do their job, a modern tribune and their family would require lifetime immunity from local law enforcement. To enforce this immunity, any interaction by local law enforcement would need to be punishable by suspension and jail time and the burden is strict liability.

But the tribune could not be a position of total local authority. Their powers would need to be constrained to local government officials. And they would need to be under the jurisdiction of country Sheriff's or State police.

This would break the incestuous relationships between the DA office, the police, and the judiciary.
Highlights of women’s earnings in 2013 [pdf]
Agreed! And believe it or not, there are people who don't have 'social accounts'. (Yes, quite normal thanks, no obvious lesions)
Show HN: Twilio API – sending SMS texts with R and rCurl
I recently felt that effect in an old norse class here in Germany.

I had to translate brast into German.
Bresta follows the 3rd class of strong verbs (old norse still has more or less rules for the strong verbs):
bresta, brast, (brustum,) brostit - to burst, bursted, burst (archaic: to burst, brast, bursten)

The same verb also exists in German:
bersten, barst, geborsten

However it's not that common today and the past tense is also extremely uncommon in speach. This led me inflect it weak (regular).
If a smart guy said something that contradicted my views, I might hesitate before doubting him. He is smart, after all. Possibly even smarter than me.
> I may not have the cash rolling in, but at least I'm in control of my destiny. Hey Ma, I'm moving in!

How are people who don't have a meaningful source of income and who are dependent on their parents for shelter any more in control of their destinies than corporate worker bees?
yeah, a big problem with the whole "Don't need BigCo's job cuz I'm running a SV startup!" narrative is that it's really only accessible for people who already belonged to pretty privileged classes (exceptions exist, obviously.)

A portion of the population does not get opportunities to develop these skills and were once allowed low-skilled jobs that paid "decently" but have now found themselves squeezed due to inflation and companies hoarding cash instead of spending it.
I stated up front that I am totally biased. I provided multiple links backing up my statements. Nothing I've said here is unfounded.

The only FUD here is advertising a piece of software as a high performance embedded database when in fact it's not suitable for such use on its own. The most viable use cases the authors have presented is when using MDBM as part of a larger distributed system such that the loss of a single DB instance isn't fatal. The above comment talks about restoring from a log, but the actual log mechanism isn't part of MDBM. I.e., MDBM is incomplete on its own and you must provide additional pieces in order to use it effectively.

I'm not solely interested in promoting my own DB. If you read the On-Disk microbenchmarks I linked you'll see that there's a broad range of use cases where LMDB gets trounced by LevelDB and other LSMs. I'm interested in facts.

From the original link:

"On clean shutdown of the machine, all of the MDBM data will be flushed to disk. However, in cases like power-failure and hardware problems, it’s possible for data to be lost, and the resulting DB to be corrupted. MDBM includes a tool to check DB consistency. However, you should always have contingencies. One way or another this is some form of redundancy…"

The fact is, this is a system that can lose data on a crash and it doesn't include its own recovery mechanism. Without such a mechanism you can't call it a persistent data store because MDBM by itself is not persistent.
Active_emoji – A collection of emoji aliases for core Ruby methods
Some curious search terms denied to the Chinese
Kasparov: Take the Offensive Against Baghdad--and Damascus, Tehran and Riyadh
At least you didn't invest in Teledesic...
I worked at Sony from 2004 -2007. They're software engineering talent is far from top tier. A big part of the reason is their comp packages. Salaries are average, bonuses way below avg, and they don't give any equity incentives (even ESPP) to anyone below VP level. I W-2ed about 5-7% more than my base salary. Compare that to Intuit, right down the highway in San Diego, where I made ~50% more than my base once my options and RSUs started kicking in along with a 25% bonus plan.
Angry Birds killer game
Reference: The Princess Bride
:P
What's JAVA?
This looks absolutely awful. Great features, bad execution. Shouldn't this UI look at least as nice as the Blackberry Playbook from 2011?
"Men Who Don’t Work – And What They Do Instead"

Surprised that "read HN" isn't listed as one of the "insteads". Which reminds me, I really ought to do some work.
Take a look at dss from AT&T AST tools:

http://www2.research.att.com/~astopen/dss/dss.html

http://www2.research.att.com/~astopen/publications/dss-2004....
Classic lump of labor fallacy.

That fallacy is far from proven, see e.g. http://econpapers.repec.org/article/tafrsocec/v_3a65_3ay_3a2...
Apple's 'unwritten rules' spark discontent for some app developers
I just hope people will eventually stop typing "payed" for paid and "loose" for lose.
New Pricing Plans for RubyMotion
holy crap , seems science going to wrong direction !
You make good points, and I hadn't considered how the VM would affect things. I'm still doubtful that frequent rewrites of the same file would actually hit the flash of the SSD, but with much less certainty. If it is writing this frequently, this seems like a place for an easy optimization of the VM. Or maybe I'm misunderstanding, and it's writing a series of small files rather than rewriting the same one?
I have a strange feeling that paleo etc folks already know this for years.
Skyline – Evolving CSS Architecture
Assuming you are voluntarily healthy, you'll be happy to learn that smokers and obese people are footing the bill for you. [1] Because healthy people live longer, they consume more health care dollars. Time to find something else to hate on..

(1)http://www.nytimes.com/2008/02/05/health/05iht-obese.1.97488...
Reading his comment, he seems to be referring to normal users, not things like scientific cluster jobs.

Still, I'm kind of upset with his comment.
Wall of text, my foot. You're the only one in here thinking clearly about the issue. Solidarity!
That Partido Popular brands itself as right doesn’t necessarily make it so. This policy does show the typically socialist “let’s regulate everything and remove choice” approach.

> I can't think of any EU countries with socialist governments except Austria and Denmark.

Off the top of my head, France, Czech Republic or Slovakia. And the _previous_ Czech government was a prime example of a left-leaning gov. in anything but name.
Don't they get points for being proven geniuses?

I mean, maybe you just don't see what they see or understand what they understand. It happens.

Let me put it another way.

You are asserting the conventional view.

Being a genius generally means contradicting the conventional view in useful ways.
I can't seem to get access to the site, "Database Error". Did we just cause the site to crash?
It's strange how appealing F# becomes once you realize you have the full power of the Visual Studio debugger and the .NET libraries. To someone who has mostly worked with Haskell (w.r.t. functional languages), that sounds great. Good debugging is absolutely essential - though with strongly typed functional languages, it's not often that necessary. But it's nice.

Then again, it's a very liberal language, if the end of the spectrum is Haskell. It allows side effects and mutable variables. While very convenient, nothing forces you to use these though. There are immutable data structures for everything. But it seems there are all the functional tools you'd want.

It's not Haskell, it's not pure and beautiful like it, but you still have computational expressions, which allow you to implement monads; metaprogramming, operator overloading, units of measure, and active patterns.

My only gripe is that the compiler doesn't translate functions that can return null to return an option value (i.e. Maybes), and null values in general! Would make interfacing the .NET library much cleaner. Right now I have to do something silly like this:

let notNull a = if a <> null then Some a else None

So I have to pipe every function call that may return null to this function when I'm in the Maybe monad, which is frankly a bit bothersome.

Still. Even being able to use the Maybe monad when working with .NET is really cool.
Except when you IPO you do not sell all your shares. You want the price to go up and maximize your personal upside.
And a parent (as the beginning of the essay mentions).
If you have a saved copy, could you just paste it as a edit to your comment? I'd definitely like to read it.
There were at least some studies that linked faster metabolism to shorter lifespans.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100751/

Higher Energy Expenditure in Humans Predicts Natural Mortality

I personally am trying to somewhat keep my metabolism slower by eating less often, and less in general, plus intermittent fasting. But of course everything is still open for debate.
just "these guys"? everyone will be screwed.
Too bad WinFS was canceled. Seems like no GUI support for any of these tools :(
I write with my left hand, mouse with my right hand (I think that is common). I currently live in a society where almost no one is overtly left handed, and I still get stares when I eat in public (though not as much as I used to).

I can imagine that "creative", "forward thinking", and "cognitive problems" go hand in hand: only a bit of spectrum separates the "crazy like a fox" and "crazy like a nut" (people mostly prefer conformity if we admit or not). It really isn't that surprising that lefties don't do better on average, and that we tend to do better at extremes (most of the last few presidents besides W were left handed, a lot of good programmers are, and so on).
Why are you upset with it? Without having seen his comment, so far parallel computing has brought little to consumer end users. Out of that little, by far the most of the benefit is about graphics processing in GPUs.
Goodbye Intel – My Favorite Commands
HN is not the place for contentless whining.
The gene that jumped
Show HN: One-file composer scripts, run PHP-Gists
Retail robots: The droid at till number 7
(Disclaimer: involved with the work linked.)

A short version of this tech report is due to appear in the January special issue on repeatable research of the Operating Systems review journal. A pre-print is available at http://www.cl.cam.ac.uk/~ms705/pub/papers/2015-osr-raft.pdf (10 pages).
Site seems to be down, saved copy: http://pastebin.com/Z08gtRFj
Joyinapp allows anyone to turn great ideas into apps
Well thanks for helping me.
Joyinapp simplifies app creation. Post your app idea, get the crowd's support, let professionals out there to bring it to fruition and share revenues with your backers.
A female documentary maker visits Indian  village, exposes the feminist media
> You make several false assumptions or gross misunderstandings of how language changes.

That's a little over the top. I only made a few claims, none specific to English:

Claim #1: There a processes that create and remove irregularities in a language. Some of these can occur in isolation, some are interactions with other languages.

Claim #2: At the very least, the ones resulting from interaction will continue to occur in the future. That is, we still have wars and immigration.

Claim #3: Implicit to my argument is my opinion that the creations occur approximately at the rate of the removals.

Certainly #3 there is the hardest to justify (and I only offer "they aren't gone yet" as my evidence). A much easier and not too different claim is "we won't reach 100% regularity" and if you like you can pretend that I argued that instead as it's not too different a claim. But "gross misunderstanding" seems unfair.

So which of these is a gross misunderstanding of language changes?
YouTube Now Lets You Make GIFs from Videos
Without the virtual file system, does this work by hashing the files? That would make it very slow to use on larger files. If I was to tag my movie collection, would TMSU have to load every byte of every movie in order to show the file tags?
You are very lucky. I had a script scrape that site (not sure if I broke their TOS) and send me an SMS about 5-10 minutes before a visible pass of something bright including Iridium flares, but I found that even if you know the exact time and direction of where it will happen it is still easy to miss it. It's very nice to see one when you do. If the sky is dark you can often see the satellite before and after it goes bright, but I've seen one shine through a blue sky which must be perplexing to spot by accident by people who don't know about these.
semver has a special case for 0.x, which is basically "before 1.0 there are no guarantees". In their words:

> Major version zero (0.y.z) is for initial development. Anything may change at any time. The public API should not be considered stable.

(Yes, this means that you can use 0.x and declare yourself "semver compatible" and break on any patch release)
What's to say that "payed" won't end up winning in the end? I mean, it's a hell of a lot more logical, pay->payed, than pay->paid.

The really amusing part about loose vs. lose is that both have a negative connotation, so the similarity in sense lends a dissonance to the "attuned eye" not unlike two musical notes slightly off pitch played interchangeably.

If you want to control language evolution, perhaps you'd prefer the existence of something like the Académie Française and invented words like "courriel"?
Is the arrayMinimum function deliberately wrong? I hope so...
Thanks! It's still down
Heavily editorialized title. Actual quote:

> Parallel stupid small cores without caches are horrible unless you have a very specific load that is hugely regular (ie graphics).

And

> The only place where parallelism matters is in graphics or on the server side, where we already largely have it. Pushing it anywhere else is just pointless.

Edit: "editorialized" meaning "choosing the most extreme quote of a rant"
Except the education system is bad at picking winners. What's in demand when you're in highschool is not what's in demand by the time you're entering the workforce.
"Actually it does validate the mystical approach for that particular scientist. YMMV, however that's how that person gained inspiration & approached the problem"

Well, yes. But the headline was a bit more generalizing than that which I found too silly not to comment upon. Richard Feynman played the bongos - but I don't think that blurs the boundary between drumming and science.
For those of us who actually ship code, I'd like to suggest khash[1], which is a pretty nice implementation of a hash table in C. It uses lot's of macros, so if you're looking for a brain teaser you will be satisfied as well :)

[1]: http://attractivechaos.github.io/klib/#Khash%3A%20generic%20...
It was perhaps written to long and you probably have a different opinion than mine. Noticing you are a Belgian ;)

TLDR;

To much people just strike against the current governement and unwillingness to work (longer) here in Belgium.

Because you're a Belgian and probably have a personal opinion: Jean Luc Dehaene did 3 step-indexes and he was a hero. Now, they want to do 1 without the socialists and it's like Belgium is on fire.

The strikers get 30 € / day and unions get 313 € / month for every unemployed person... Do you think that's normal/good?

I'm not claiming "right" os good, nor do i claim "left" is good. A combination of both would be good, without the extremism! But most of all, i'd love to see some common sense in unions and some radical politicians.
It looks like a tool specifically designed to pirate apps that are available from the official App store.
Adobe Acquires Fotolia for $800M
Show HN: Bluffr – Your guide to football parlance
Blocking Serotonin in Gut Reverses Osteoporosis in Mice
http://www.medpagetoday.com/Endocrinology/Osteoporosis/18346
> We'll be speaking in python no doubt.

(Or this (Lisp (to (indicate identation-level) (using (pitch voice)))))
> companies hoarding cash instead of spending it

I've heard this sentiment many times but I've wondered if there's an economic fallacy there. Would the economy be better off if lots of companies stopped hoarding cash and hired lots of new employees? Or would there be side-effects like inflation, or some effect of pulling out cash from whatever it was invested in, etc.?

Serious question.
This is faster because it's doing a linear search.
Linear search is really fast when 'n' is small.
But it's horribly slow when 'n' is large.
But since the http route matching is never going to come up at all in your profiling unless 'n' is large it's better to have a router that handles large values of 'n'.
I would like to point that, although America doesn't have a monopoly on the crazy, is also a country that doesn't have an structured mental healthcare system. When you have easily available guns + mentally ill people roaming freely the streets... You have a problem.
I have never had 'a job' and had startups (and later mature companies) since I was 15 (I am 40 now). I am not sure what age you are, but you need to know this thing for sure if you are past, I think, around 30 as running a life like this can be very painful. There simply is a tiny chance of 'big success' while most just live in almost poverty the first 20-30 years of doing this. That's also why I think you are probably young and haven't seen that yet ; most give up and tell stories to their kids later about it.

Not to squash your enthusiasm; just saying that 'control of my destiny' is mostly not true at all; you are being lived by actual constraints of life. If you get a mortgage, kids, spouse, investors etc these constraints can easily 'live' you instead of you controlling anything. I was lucky, but just saying to be careful in thinking this and keep tabs on the 'do I actually still like this' factor. A regular job, for most of my friends who started out with me, was a blessing.
The X and Y axes do not have the same units, so scaling them this way is meaningless. The key point is that while there line has slope, the spread of the data is much larger.

I.e., the ideology of the study's author gives you very little information about the numerical values in the study.
He also excluded ASICs and the like and focused on GP CPUs. Not sure why that'd upset you - what would you use a desktop (assuming x86 or x64) CPU to do that actually requires explicit parallelism?
TagSpaces has excellent GUI support.
Naw. Wordpress on a budget VPS caused it to crash.
I don't understand the original quote to be a proposition. I think what it's trying to say is "Matz is nice so we too aspire to be nice". It's not descriptive, it's perscriptive.
I was watching an episode of IT Crowd, and thought this would be a fun idea. So I spent some time putting together this MVP. Feedback is welcomed.