skysight-inc/HackerNews huggingface dataset:
Senior Python Data Scientist and Senior Software Engineer - Recursion Pharmaceuticals

Question for you: What's the most challenging, impactful, rewarding set of computational problems you could be working on, that will really change lives?

We’re a small and fast-growing biotech startup with an amazing set of advisors including the Broad’s Anne Carpenter, and we're using high throughput genetic perturbation experiments in human cells, automated image segmentation and quantitation of hundreds of features for every cell, and machine learning and statistics to find new treatments for rare genetic diseases faster than anyone has previously thought possible. If that sounds like a lot of biology, don’t worry—you’ll be up to speed in a week or two. Just know this: there are more than 5,000 rare genetic diseases, in total affecting more than 10 million people in the US alone, and only a handful are treatable. We aim to find treatments for 100 of them in the next 10 years. See who we are at http://www.recursionpharma.com/team

We’re looking for exceptional computational scientists to help lead our analysis efforts, with the following criteria:

- Native-level fluency in probability, statistics and modeling; several years of experience in statistics, machine learning, and software development solving problems using lots of data, ideally using python’s scientific stack; thorough understanding of fundamentals of machine learning such as cross-validation and learning curves, plus an ability to explore new types of data independently and get an effective guess as to what sorts of models and assumptions make sense as a starting point.

- A track record of outstanding projects, publications, or presentations that demonstrate successful application of the above talents.

- Motivation to tackle some of the most challenging data problems around, to work with other sharp and highly-motivated individuals with diverse backgrounds, and to make lots of patients’ lives dramatically better.

- Biology background not required; intellectual curiosity and motivation to learn is critical.

- Key tools and skills (not all required): python, machine learning, sklearn, ipython, data science, pandas, interactive analysis, linux fluency, bioinformatics (definitely not required)

More details and how to reach us: http://www.recursionpharma.com/lead-python-data-scientist.ht...

More openings including software engineering roles: http://www.recursionpharma.com/careers.html

Recursion Pharmaceuticals is based in Research Park at the edge of the mountains overlooking Salt Lake City, Utah. Gorgeous hiking/running/biking is literally out our back door, and it's half an hour to 5 top ski resorts.
Disco | Houston, TX | Engineering, Operations, and Sales (also VP Engineering)

Disco makes the best legal technology in the world, and is looking for exceptional people to join us. Our goal is to automate every part of the legal profession that doesn't require human legal judgment.

Our team already includes some of the best and brightest out there, including the youngest-ever Harvard Law graduate, a YC alum, and the former CIO of Sonic Foundry.

Shoot us an email if you are looking for important societal problems and great challenges, including using machine learning to categorize legal evidence (starting in the coming months). Eventually we want to be the Google of private data.

Our engineering stack is .NET/RavenDB/Lucene, with a heavy javascript front end. If you are are great at whatever you work with, we want to talk to you, but we especially need those with experience in our stack (or front-end), or with file-type processing (extracting images and text of the files) or pdf.js. We are also looking for QA engineers - but again, if you are exceptional at whatever you do, we want to at least have a conversation!

We just raised $10M from Bessemer (and were profitable before we took funding), so we are around for the long haul.

Email me directly at gabe@csdisco.com with a short note about why you would be a good fit for Disco!

More on Disco and our team here: http://csdisco.com

Thanks for reading!
Talentry - Munich, Germany (München, Deutschland) - https://www.talentry.de/en/

We are looking for a Web/UX Designer and/or Frontend Developer.

Contact me: p.frank@talentry.de
SEEKING WORK -- Python, data, research. Berlin, Germany. Remote OK

I like to combine code, data and real-world analysis to make sense of things. I've lately done a lot of work with investigative journalists...exposing weapons sales, tracking organized crime through banking records, making tax havens more transparent than they want to be.

I'd love to apply similar approaches in other domains -- using all the tools available to help you answer some question. Could mean writing a web scraper, running a Hadoop job, or picking up the phone and calling the right expert.

I know my way around big data, though I find smaller datasets equally valuable. I've worked on a multi-terabyte mapreduce system, and the associated web service to handle 1000+ requests/second.

I'm also happy with web-dev (python, js, PHP where needed). Things I've (co-)done lately:

http://investigativedashboard.org -- site used by investigative journalist in 30+ countries for research collaboration

http://yanukovychleaks.org/en -- making public the documents of the former president of Ukraine

Remote is fine, or I can travel for up to a couple of months.

http://ohuiginn.net, email daniel@[that domain].

CV: http://ohuiginn.net/docs/cvdanohuiginn.pdf
42reports GmbH - Backend Developer - Berlin, Germany

https://42reports.com

About us

- We are building an innovative SaaS Analytics Tool that consumes millions of data points every day

- We change the offline retail industry by giving them access to tools from the online world

- We are solving challenges on database performance, intelligent data aggregation and interpretation and building scalable APIs

- We rely heavily on Python, PostgreSQL and C as well as Django, RabbitMQ and AngularJS

- We want you as a full member of our international 42reports team and provide you with full access into all development areas: from hardware sensors to backend applications and frontend applications

About you

- You want to develop reliable, high performing backend systems

- You have solid experience developing software in Python

- You know at least one other programming language well: e.g. C, Go or Java

- You have a good understanding of relational database systems

- You have a passion for developing software which actually solves a real problem

- You are curious about new technologies, believe in agile development and have the ambition to learn beyond your current fields of expertise

- Ideally, but not necessarily, you also already have experience processing large amounts of time-series data, developing automatic deployment tools or using machine learning algorithms

Job Perks

- A highly motivated team of embedded, backend and frontend developers as well as mathematicians that you can rely on, learn from and support with your own experiences

- A great company culture with team spirit, a common vision, serious coffee, Friday beer and weekends off

- An environment geared towards learning and professional development to make the most of your potential

- Competitive compensation that matches your abilities and potential
Shoot an email to HE. Their support for this free service is better than most commercial support teams I've interacted with.

Also, don't discount that it's possible that the other end of the equation, the server you are trying to reach, has poor IPv6 connectivity. Fire up a Digital Ocean instance for an hour (it'll cost you $0.10) and see if the site is slow from everywhere.

I've been using HE.net's tunnels for a good long while now and they've been great for me.
I'm not sure how they came to the conclusion that the hackers have a "banking background".

Is it that difficult to determine that hacking certain people's emails is likely to lead to insider trading tips? Do you need a "banking background" or "worked on Wall Street" experience for that? It's quite a leap.
Developers, want better software? Stop relying on buggy code
Fieldbook | San Mateo, CA | Software Engineer | Full time | https://fieldbookapp.com

Fieldbook is an information tool that lets you track and organize anything in simple data tables. It's for anyone who is frustrated with using a spreadsheet like a database – to track projects, sales leads, recruiting, or anything.

Demo video (3 minutes): https://fieldbookapp.com

Our mission is to allow anyone to create a database, just as easily as they can create a spreadsheet. To do this, we're rethinking what a tool for working with structured data should look like, from the ground up.

The founders are Jason Crawford (CEO) and Ben Bernard (CTO); both have strong technical backgrounds and leadership experience at companies including Amazon and Google. Fieldbook's investors include Pejman Mar Ventures, Mitch Kapor (Lotus), Steven Sinofsky (Microsoft) and Naval Ravikant (AngelList).

We are building an ownership culture where employees take pride in their work and put the customer first. If you are a versatile, full-stack engineer, there is a window of opportunity now to join us in making this vision a reality – and to have a big impact on the product and on the company itself.

Contact: Jason Crawford, jason@fieldbookapp.com
Making Magic with F# Type Providers
I haven't used a mouse on my desktop (any desktop, really) in over four years - I use Apple's Magic Trackpad to get the same experience and precision I have on my laptop.

That said, considering that many more people use laptops these days, mouse chording is somewhat passé and hasn't caught up with the times. But I'd actually rather have the window manager work more like other environments (without using different buttons to get different behavior on window edges) and would love an actual compositor and better font rendering.
For the curious, the morse translates to MATASANOSECURITY.

edit: typo
And yet, you're paying those engineers (and every other employee) to waste their time using N different non-integrated services, all of which change at random whenever a new release is pushed out, disrupting your processes.

I've been involved in this side of a startup 3 different times over a couple decades: IT systems are not a full time job for a startup. They're not even a part time job. They're an every-once-in-a-while type job. At <30 people, all you need is one engineer that can also run a single small internal server. Just one.
Service Worker. The API to enable the future of web apps?
The Syntax of Taste: Refactoring Conditionals
All you need is a firewall. NAT is not a security feature: it just has security implications. In IPv4 land, it's the firewall that does all the port forwarding, etc. anyways.

If you are running IPv6, get a nice OpenWRT router, where the firewall is enabled by default.
SEEKING FREELANCER - remote then onsite for 4 days at an event, London

I'm looking for a current student or recent graduate who can build iPhone apps. Currently collaborating with Pearson on a project for a very simple app to be produced to Jan 2015.

You'll need a free account first (because the project carries an NDA) which you can sign up for here: http://www.codingcupboard.com/register

Details & application process here: http://www.codingcupboard.com/projects/project/public/?proje...
He does all that and has two young kids. There goes my excuse.
Ben Horowitz's book 'The Hard Thing About Hard Things' is a bit of a goldmine for someone in your shoes: http://www.amazon.co.uk/The-Hard-Thing-About-Things/dp/00622...
Lead Designer - Starling Bank, London, UK

Starling is rebuilding a bank for the internet. API-driven, mobile-first, based on an entirely new technology stack. We're applying for a full UK & European banking licence and raising significant funding.

As lead designer, you'll be responsible for delivering our customer-facing iPhone and Android apps, working with a team of world-class mobile engineers.

Come and help us redefine banking!

tom@starlingbank.co.uk
I'm not sure it fits the needs.

Based on what I read here, it seems to be the equivalent of "Mysql users/Postgres roles" applied to ES.

I don't know how they will propose the feature but if we compare to mysql, it wouldn't be possible to map application permissions to mysql users/privileges. Mysql privileges are for "administration" accounts but not for the user management of the application itself.

Anyhow, Shield doesn't isn't likely to be an open source product. Tuleap, on its side, is 100% open source so it's a no go !
ACLU Fights for Limits on Cellphone Tracking
Ask HN: Pre-Valuation Stock Options Advice
I recently left a pre-valuation company after being fully vested with a good chunk of NSO stock options. The company is doing well and is making good profits. Since the company has been completely bootstrapped from the beginning (over five years ago) and with no plans on taking on outside funding, it's difficult to determine the valuation so it sounds like the company is currently using a third party to come up with the valuation. I need to exercise my stocks within a certain window (most likely after third party valuation) but I was hoping to gather some advice from others on the best way to proceed on my end.

Is it common to use a third party to determine valuation on a bootstrapped company?

Any advice with tax implications when exercising NSO stock options?

Also, myself and the company is based in the U.S. Just mentioning in case it affects laws and/or taxes.
This entire thing is just a rant against specialization and abstraction. Both in economics and computer programming. This is just ridiculous. Without specialization the world wouldn't function at all. No single human being can build a car by himself from raw materials. Programmers shouldn't be expected to write their web apps in assembly, and can you imagine the mess if everyone tried that.

The author starts out with a legitimate complaint that things are suboptimal. But his cure is worse than the disease.
Microsoft Buying Mobile Email Startup Acompli for More Than $200M
A great way to gain more experience is to contribute to open source.

One way would be to join the Debian mono group to help improve the C#/.NET stack in Linux Mint (they pull packages from Debian):

https://wiki.debian.org/Teams/DebianMonoGroup

Similar teams exist in Debian for many all languages.
Racism, arrogance and ignorance
Nimblelight - Philadelphia, PA

http://nimblelight.com/jobs/

BACK END DEVELOPER

We’re looking for a back end programmer with a solid foundation in web development. The ideal candidate is excited about technology, can control website functionality with PHP or .NET, wrangle servers into line with SQL, and communicate with the front end via AJAX. This is a full-time position.

QUALIFICATIONS

– An insatiable appetite for learning

– A show-off with PHP, C#, or any other major language

– Strong opinions on frameworks, file structures, and optimal solutions

– Fluency in system and server administration and troubleshooting

– Working knowledge of AJAX and back-end --> front-end flow

– Familiar with cross platform testing, devices and browsers

– Experience with version/source control (Subversion, SVN, Git, etc.)

– Working knowledge of programming best practices

------------------------------

DESIGNER / FRONT END DEVELOPER

We're looking for a designer and front-end developer with a strong desire to bridge the gap between art and code. The ideal candidate has experience creating clean, responsive mockups, is a show-off with HTML/CSS, and understands how people use technology. Please include a link to your portfolio when applying. This is a full time or part time position.

QUALIFICATIONS

– An insatiable appetite for learning

– Strong visual aesthetic

– Awareness of contemporary design and UX trends

– Sharp problem-solving skills

– Ability to adapt and thrive in various roles

– Proficient in Photoshop CS5 or higher

– Experience coding websites with HTML, CSS, and Javascript/JQuery

– Ability to identify what constitutes a brand

– Professional and confident

------------------------------

BENEFITS

- Competitive Salary

- Comprehensive Healthcare Plan

- Company lunch and happy hours

- Gorgeous working environment

- Paid time off for holidays

- Paid sick or personal days

- Every day is "Casual Friday"
Unfortunately we don't support remote employees right now.

Our products are physical robots, and we all need access to a lot of prototype hardware that is hard to replicate or use remotely.
You're actually wrong.

(1) "A JSON text ... conforms to the JSON value
grammar."

(2) The entire standard for the object grammar is, "An object structure is represented as a pair of curly bracket tokens surrounding zero or more name/value pairs. A name is a string. A single colon token follows each name, separating the name from the value. A single comma token separates a value from a following name."

In other words, people SHOULD ignore both of those, because ignoring both of those is a part of the ECMA-404 JSON standard. (The latter actually wasn't even a part of RFC 4627; the operative word there was SHOULD, not MUST.)
"very year we take the company overseas for a month (on your own dime, sorry)"

You make your employees pay to travel for work?
Buggy civilization? I don't think so, the improvement through evolution favors those who aim to grow exponentially. The alternative, micromanaging extremely complex systems, will unfortunately fail.

Trying to force the global economic system into a software analogy just feels silly and wrong.
You should be able to do this with Zapier.com: http://i.imgur.com/CqfQKDN.png

Alternatively, look at the API docs of the two sites and write a script to do the subscribing, then make it a cron job.
Location: Germany

Remote: Only, please. Part time in the beginning.

Willing to relocate: not for 2014, likely for 2015

Technologies: Wordpress/Drupal/CodeIgniter/Yii (Components, Hacks, Themes, you name it - I've done it), JavaScript
(jQuery/Backbone/some Angular), Django (more Python than Django).

Resume: Upon request.

Email: admin (at) kidsil.net

Over 15 Years Web development experience (65% Back end, 35% Front end).
Location: Roorkee, India

Remote: Yes

Willing to Relocate: Yes

Technologies: JavaScript, GoLang, PHP, Python, Rails, Node.js, C++, Git, Matlab, SQL, Bash Scripting, Linux

Email: me@apsdehal.in

Github: http://github.com/apsdehal

Portfolio/Website: http://apsdehal.in

I'm a student developer looking for Summer 2015 internship.

Google Summer of Code 2014 internee with MediaWiki, Winter Intern with Wingify.

I'm interested in Web Development, API's, Data Analysis/Mining and Networking
Unfortunately, it's anything that's slow... When I've got a tunnel live, Google properties and Facebook are pretty much unusable. Weirdly, sometimes it'll work fine... Other times it won't. (The server I'm testing against with is my personal site, https://nuxx.net, which has great IPv6 connectivity already. I just don't want to tunnel my home connection through it because that'll seriously push up the bandwidth use of the hosted server.)

There's two things that I haven't taken the time to rule out yet: my router potentially being problematic (it's an Apple Airport that otherwise works well) and the ISP slowing down tunneled traffic. The former would require setting up a new router, and the latter... I'm not sure how I'd do that yet. IPv6 connectivity had been working fine until a month or two ago when things just went weird.

Good thought on sending HE a message... I'll do that later today. Maybe there's something they've run into before with this combo. When their tunnel was up and working great it was surprisingly nice.
Location: Delhi [or Remote]

Remote: Yes

Willing to relocate: Yes

Technologies: Python, Django, Mobile(iOS, Android), jQuery, Bootstrap, Backbone, Angular, Docker, Chef, Ansible, AWS, Golang, Clojure

Resume: http://www.linkedin.com/in/sidmitra

Github: http://github.com/sidmitra

Homepage: http://www.sidmitra.com

Email: sidmitra.del @@@@@@gmail.com

Some examples from the portfolio:

* http://publish.saxo.com - publishing platform where anyone can publish e-books, and soon printed books (print on demand) and online courses.

* http://www.ecomarket.com - An online marketplace for ethical and eco friendly products.

*
http://www.teaspiller.com - An online marketplace for tax experts. [Recently acquired by Intuit]

* http://www.hypedsound.com - A platform for music artists to share their content from various networks.

* http://www.grapevinelogic.com - A platform for advertisers to work with Youtube content creators.
I don't understand why you would host your source code externally?

You can buy Atlassian Stash, once, for $1800/25 users, and use it forever: https://www.atlassian.com/software/stash/pricing
SEEKING WORK, in London or remote within daylight work hours

Technologies: C#/.NET, Python, Javascript

Linkedin: http://tinyurl.com/kseq69j (has link to github)

Email: ac.ikswokroip@keraj reversed

Web developer. I've done some of my best work as prototypes and internal proof-of-concepts. Would love to do something related to energy efficiency, transport, or sustainability: smart meters and devices, transport software, renewable energy, etc.
I feel like there is more to the story...
Location: Morelia, Mexico

Remote: Yes

Willing to relocate: No

Technologies: Django, Python, AWS, Javascript, Coffeescript, Gulp, Nodejs, Backbone, Handlebars, Stylus/LESS/SASS, Requirejs, Vagrant, Meteor, Websockets/Push, Cordova/Phonegap, Sematic HTML, QA/Code review, PSQL, MongoDB, MSSQL

Résumé/CV: http://andrestorres.me/resume.html

Email: andres.torres.marroquin+hn@gmail.com
How is that a bad thing? And how would it be improved by everyone making their own pencils?
KnockoutJS is great. It's small, simple, stable, it works on every browser, even IE6 and mixing it in with other technologies is no problem. Being able to easily read through the entire code of KnockoutJS is another big plus. I've used this on a few big projects so far and it's just a pleasure to work with.
You are correct! It almost looks like a page divider, I've just thrown in a comment for now to help others until I figure out a better solution. The reading amount solution makes perfect sense and will also throw that in when I can.
yes that's the tradeoff/investment, where people differ of opinion and I (very technical person, not management/paper pusher), find it more important to have in-house capabilities (even at higher cost) then to simply rely on a third party vendor.

Plus that you are not making any third party aware of anything, as you don't need them. And might save you a lot of hassle in the middle of the night and you need vendor support, which generally at such hours could generate even more cost.

In my humble opinion, technical pov, the more you do in-house, and the less you rely on third parties, the more freedom the company has.

Also any in-house developed product, could be sold, generating income. Also, i believe, that developing your own, gives you a certain knowledge which you don't get if you are simply adopting third party software.

It's of course way easier/more clear to calculate ROI when you spending specific amounts instead of investing in knowledge, control and self power. The returns on that can very a lot.

But, generally speaking, things are only 'expensive' if you think they are not worth it.
Yeah, the bug report response is a little silly.

But the OP's complaint is also a little silly, given that his Vapory library works by writing a temporary scene file, then running the POVRay renderer executable to generate an image file. The same technique can be done with any renderer with a standalone executable, which includes Blender -- you don't need direct access to Blender's internal Python API.

In Blender's case, you might need to write a library to author .blend files, which is non-trivial. But it might also be possible to use Blender's .py script files as an ad-hoc scene description format.