skysight-inc/HackerNews huggingface dataset:
> They are using the yogurt rule

Ahh, you mentioned Autism spectrum, so I assumed that couldn't be the case.

> we have metagenomics on them (v4 rDNA sequence reads) not full seq data

There is plenty of genomic data beyond 16S. For the HMP, full sequencing of selected strains as well as hundreds of WGS metagenomes were done. And that's almost old news now, I'm sure there is even more being done currently. The result is basically either a full genome, or a set of giant chunks of the genome of the abundant microbes there. We don’t have all the genomes closed (although some are in the process!) but closing a genome is a very high bar and probably not worth it when you can get a lot of data from a fairly good set of large contigs.

Can the assemblies be chimeric/wrong/whatever? sure, some of them will be, but at this point most assemblies are fairly good :)
I like how they consider birth as "construction ready".

Oh and a side note. Being based off the original BSD its roots go back to 1977 and even earlier.

https://upload.wikimedia.org/wikipedia/commons/7/77/Unix_his...
PPD – Post Party Depression Http://ppd-post-party-depression.urbanup.com/7938494
Downvoting comments like that is pointless and should be banned.
Oh really? I thought that it forced you to go back to the app if you use a non-U2F browser.
Agreed, but that's actually a separate problem. There are so few CEOs relative to average workers that their aggregate pay isn't enough to explain why workers in the west aren't experiencing wage growth.
Internet Archive now lets you play 900 classic arcade games
Can you explain a bit about that? I followed the links in the article, and found them to be quite good, so reading this is kinda surprising. From my quick Googling, it seems like maybe someone thought he was pretentious, but can't really seem to get any more solid info. Did he do something that caused people to hate him?
This is where some well-phrased xenophobia would be really helpful. "Comey wants to hand your texts over to the Chinese" or something like that.

It has the benefit of being more or less accurate; there is no way, if the architecture technically supports it, that it won't be forced by any legal jurisdiction that can bring sufficient pressure. This happened already with Blackberry Messenger.
I was under the impression that a late-2013 MBP does support HiDPI with 4K displays. Is it a hardware issue or a software one?
Seeking to directly and intentionally harm the rights of the very citizens you're supposed to be protecting, makes you malicious. It is that simple.

It doesn't matter whether Comey is a nice guy or whether he thinks he is doing right. What matters is what the guy actually does. His actions make him malicious. Putin might be insane or delusional and think what he does benefits the Russian people - that doesn't mean he isn't malicious.
If not less.

I can't do traditional meetups here anymore, I've met maybe 2-3 technical people who even know how to code a basic webpage and I've gone to over 2 dozens in Venice/SM and some "notable organizations" - just tons of "biz dev" "marketing" and "media" people, great, but I guess WE are all looking for more hardcore tech-oriented people here.

I've met some great people at UCLA Venture Fund events (look them up) but what we should all do in this thread is organize a small HN meetup in LA.

LA is without a doubt growing, slowly but surely, and heading into the tech startup trajectory, even with all all the wantrepreneurs and media guys... Engineers and anyone with face stuck to screen for 10+ hours a day is going to have a tough time meeting like minded people in real life, hence is the nature of the beast.

What could be more powerful than bright people getting together to discuss cool stuff.
A more interesting report would be which ISP by country let their customers use IPv6, landline and mobile. If servers are IPv6 but people can access them only over IPv4 then we're still at IPv4.
Ha! Dyslexics untie. After I re-read the title correctly I half wished this would be about projecting random dot stereograms on the ceiling / wall.

Dot stereograms might be hard as it would be difficult to get fine dots. But in principle it should be possible to project stereograms. That would be one perverse pun on 3D.
How to Reinvent a $38B Company
I assume you are talking about http://goodfil.ms/?
For writing code, you can use nitrous.io or c9.io to use your tablet browser as a full IDE on the cloud. I've tried this use case before and it works ok.
>The US already makes the USSR look like amateur hour...

Kind of a hard comparison to make, considering the USSR dissolved in 1991. That was well before internet access and mobile devices became a part of daily life, let alone existed in non-primitive form.
Image recognition in mobile game testing
The Dell UP2414Q. 24" turns out to be the maximum size that looks decent at 4K. I tried 28" and 30" 4K monitors, and you could still totally see the pixels.
Articles say an 'unexpected benefit' is reduced prop noise. They did study the effect of bubbles on prop efficiency and apparently it is minimal, but noise is reduced significantly.
8 Entrepreneurship Lessons from a Venture Capitalist
Wow a new OS for my Amstrad CPC. If only I knew how to transfer data unto it.
I'm tempted to steal your concept and build a version of this for video games.
> the issue you're pointing at is that capitalism doesn't function well in a post-scarcity environment, which we're entering.

A literally post-scarcity environment is not a problem because it makes the price of everything zero. Food is free, shelter is free, medical care is free, you don't need a job. Do whatever you want all day, it's not a problem.

The problem is that what we're entering is not a post-scarcity environment, it's an environment where things many people don't already have, like energy or land, become more scarce and thus more valuable than the things they do have, like the ability to perform unskilled labor.

In theory capitalism works fine in that situation. If people can't afford rent or home ownership then the price of housing should come down, because the supply of housing and the number of people who need it haven't really changed, so if people have less money then landlords and home sellers can no longer charge as much.

The problem is that we interfere with that process -- the housing crash was a market correction. Instead of letting that correction happen all at once, we bailed out the banks. So now the banks that didn't file for bankruptcy and liquidate their assets are sitting on thousands and thousands of foreclosed homes and intentionally keeping them off the market in order to backstop housing prices and prevent even more foreclosures. But the result is a significant artificial inflation of housing costs that comes directly out of the pockets of people in poverty.
Hong Kong and Singapore have very high inequality.
Best Vaporizers 2014 – The Healthy Alternative to Smoking
I honestly don't get Chipotle. The food there is bland and tasteless to me -- not even Taco Bell quality, much less what you'd get in a good Mexican or Tex-Mex restaurant.

Maybe it's a local artifact. Quite a few other chains in this area seem to be afraid of using any actual spices in their food.
Silently and spastically splaying taut fingers to get you the fuck out of his office and stop interrupting a man who works for a living, the great Tom West past 19 May 2011:

http://en.wikipedia.org/wiki/Tom_West
There is Zoho mail[1] - 1 domain, 10 users, 5Gb per user.

You can also try Yandex mail for domains[2] (1000 users and unlimited storage), but you will have to use Google translate to add domain - unlike mail itself, this pages are in Russian only[3].

[1]http://www.zoho.com/mail/zohomail-pricing.html

[2]https://pdd.yandex.ru/domains_add/

[3]http://www.blogsynthesis.com/yandex-mail-setup-for-custom-do...
I think this is largely a hoax and they already have access to the said data.
No, it is readable when it is on company servers.

http://images.apple.com/privacy/docs/legal-process-guideline...

"iCloud is Apple’s cloud service that allows users to access their music, photos, documents, and more from all their devices. iCloud also enables subscribers to back up their iOS devices to iCloud. With the iCloud service, subscribers can set up an iCloud.com email account. iCloud email domains can be @icloud.com, @me.com and @mac.com. iCloud data is encrypted 3wherever an iCloud server is located. When third-party vendors are used to store data, Apple never gives them the keys. Apple retains the encryption keys in its U.S. data centers. The following information may be available from iCloud..."

"...i. Subscriber Information ... name, physical address, email address, and telephone number ... iCloud subscriber information and connection logs with IP addresses ... Mail Logs ... Email Content ... Other iCloud Content. Photo Stream, Docs, Contacts, Calendars, Bookmarks, iOS Device Backups ... photos, documents, contacts, calendars, bookmarks ... photos and videos in the users’ camera roll, device settings, app data, iMessage, SMS, and MMS messages and voicemail.

iCloud content may be provided in response to a search warrant issued upon a showing of probable cause."

It is only data stored directly on devices that Apple claims it can no longer give access for. Note that a lot of data gets synced without user knowledge including working drafts of documents: http://mjtsai.com/blog/2014/10/26/yosemite-uploads-unsaved-d...
The micro-bubbles are generated by heating, then cooling,
water to avoid releasing it as steam.

That sounds fairly benign. Can anyone explain the mechanism?
The Truth About 'Growth Hacking'
"Freest Economies"? You mean the biggest leach in modern history. They send all of their children to be educated abroad. The rely on the security provided by our military. And they provide safe harbor for all the rich tax evaders who made their money off the innovation created by countries that actually invest in research. Then there's also all the poor as dirt neighboring countries who does all the work for them and live in the pollution byproducts.

We shouldn't measure how well the kingdom is doing by the gloss of the marbles at the king's court.
10 Principales riesgos de radiaciones en oficinas
I am in Inglewood,CA. Working on RubyMotion iOS Apps. Looking to get into building prototypes and maybe a part-time iOS Business. I am also heavily ready to jump into hyperlocal marketing apps monetized with automated e-commerce accounts.
Consider instead a LG 34UM94, see review at https://www.youtube.com/watch?v=KnrxNfxRK_4
I want some sockpuppets just to upvote this more times.
> I think he very clearly understands all the applications.

Really? And what are you basing that opinion off of exactly?

The only applications he mentions in his post relate to taxes and credit card fees. If he had any understanding of the other uses like multiparty transactions, timestamping, identity management, voting, derivatives, and trustfree contracts, then he failed to say anything to convey that awareness in his writing.

> Again, I think you misread the article. It isn't that he is unwilling to learn something. He's learned a great deal and concluded that it makes his life more difficult.

I didn't misread anything. Rather, he miswrote by conflating his opinions of a single bitcoin service with the entire underlying protocol.
Twice as fast, in some cases.

I don't think--and again, this is just my opinion--that giving up the simplicity of the protocol that has somehow brought us in the last twenty years from barely functioning text to the modern web is a good idea. I believe that especially given that the big benefits seem predicated on very centralized authorities and large-scale companies.

If you're Google or Facebook or Twitter, this is great. If you're anyone else, it's not really a huge win.
I generate a one-time card number for each online purchase. Only valid for a specific time and up to a specific account. Supporter by some banks. Pretty good solution in my opinion.
It's a shame they dropped mandatory encryption. Now "HTTP2 all the things" doesn't mean "encrypt all the things" anymore.
Yes. I've been recommending that for years, actually: http://the.taoofmac.com/space/HOWTO/Switch
https://datavibe.net/~sneak/20141023/wtf-icloud/

They do store drafts of documents transparently in iCloud and confirm that they will give content stored in iCloud to law enforcement.

http://images.apple.com/privacy/docs/legal-process-guideline...

If you look at the design of the Secure Enclave's Key Derivation Function it pulls in data from a unique ID burned in by the manufacturer and a small pin code provided by the customer. Apple claims it can not get the data because it knows neither the UID or the code.

However, the manufacturer of the Secure Enclave does/will know the UID and a user passcode can easily be brute forced. If law enforcement have enough leverage to get UIDs then the system is moot.
30% faster... IF you've got your page split up into 78 requests on 12 different hosts using 1.2 MB.

Btw, do they still have the special case handling of headers and whatnot that hardcodes today's implementation details and "best practies" into the protocol we're supposed to use for decades ahead?
So happy to see this on Hacker News. Dante is so important to us and it's great to see him get some recognition.
Dictating, Writing, Hiking
> Sorry, I didn't really get that single-sign-on and federated authentication is the same thing.

I don't think it is. SSO is a good feature, and kerberos provides it -- but I was more curious about the more general case. A solid ldap daemon with easy-to-use ssl/tls covers most of the use-cases I was thinking of.

I don't really care much about "winning arguments" -- I'm just curious about the state of secure, working federated authentication. And the fact that it needs to grip rather deeply into the system, therefore it would be nice to have it in base. Linux generally has PAM in base -- for some that is considered bad, for some it is considered convenient. I'm not really interested in judging one way or the other.

> It might be that so few people actually used it that there's no one to maintain it.

Yeah, that's the feeling I got. And it would be worse to keep something that isn't properly maintained. I guess I'd hoped some openbsd'er would hammer out a robust token/ticket based scheme without many of the flaws of kerberos (ie: hardened implementation, proper/modern cryptography primitives combined in a proper modern way, no premature optimization). That'd probably be hopeless to get to work with windows AD though, so maybe there's only a very small set of people that would care.

I'd certainly like (from a technological standpoint, anyway) something like that, that took lessons from window's kerberos/ldap/dns-story, but made something free and robust (possibly with a patch for GINA for windows) -- that allowed stuff like secure encrypted network filesystems etc.

(Come to think of it, I think the fact that I'm sort of enamoured by the concept of NFSv4 with authentication and encryption delegated to kereberos is one of the reasons why I was so surprised/disappointed. Why have ZFS and NFS without v4 and auth/enc support? So beautiful on paper. I guess that basically leaves sshfs (as OpenAFS also requires(?) kerberos).

I'd really like to see a working distributed single-sign on, single sign-off system that support (optional) caching/offline use coupled with a filesystem that is mutually authenticated (client to server, server to client) also with caching and off-line use. But that is simpler than efforts that have gone before...).
Yes. Many of the problems today have nothing to with capitalism but with government policies that are largely aimed at making those with the gold happy.

Capitalism is mainly about having markets that have competition. NO organization is suppose to have market power. This isn't really possible, but that is the concept. And we are so hugely away from it we can't call what is going on now capitalism. We have allowed people to convert what is called capitalism into an extreme political view that believes government is bad and huge corporations are good. That isn't capitalism, it isn't even an economic belief, it is a political belief.

A capitalist country has to be focused on maintaining a fair marketplace where companies can compete for business and consumers (including companies buying from each other) have the freedom to buy in a competitive market (not a market dominated by trusts, monopolies and oligopolies that break the function of markets to advantage themselves).

http://investing.curiouscatblog.net/2008/06/10/monopolies-an...
The Internet Archive Now Lets You Play 900+ Classic Arcade Games in Your Browser
In Washington DC, calling for the dismantling of the military industrial complex, an end to perpetual war, a pacifying of the increasingly violent police, and the general re-establishment of the individual rights enshrined in the Constitution.
It's interesting that the left has pretty much given up on ideas of economic equality and inclusiveness in favor of pointing and sputtering when people say things which are not politically correct. If I were a suspicious type, I'd wonder if political correctness had corporate sponsorship; it certainly seems to have paid off for the oligarchy...

To his first point, it's not really true. Many of the largest and scariest businesses are still family businesses. Louis Dreyfus Group (yes, Seinfeld girl is a scion of this $120b/yr "family business"), Cargill, Koch, Bechtel, Bloomberg, Mansfield, Kingston, Sungard, Dole, Bausch & Lomb, Deloitte, Hearst, Bosch, PWC, Aramco, Vitol, Continental grain, Scoular, Consolidated Grain & Barge, Safra Group, Armajaro. Most of these companies are deeply embedded in the power structure of their host countries and other countries. What's scary is how huge they are, and how little people are even aware of their existence. When you start looking at them, well, some of them look kind of like they are run by James Bond villains.
very pretty and usable design. found some decent films already. overall, great execution – compared to similar services I've used.

I like that it works on mobile too, but why does the page need to be reloaded when I resize the browser width? upon resizing, I lost my scroll position and I noticed the text all became red at tablet-ish width.
A note to those reading this exchange: sounds is using the tactic of replying with a list of tangentially-related, denotationally true but connotationally not-so-accurate points. If I don't spend an inordinate amount of time responding to every one of them, he can say, "Ah-ha, but you didn't address points 2, 4 and 5."

I don't like taking things meta, but it's impossible to engage in a debate when confronted with such a mess. The sad thing is unless you've been on the receiving end of this tactic before, it usually works.

Yes, all kinds of bad things have been done by the NSA, CIA, and GCHQ. But I (and the article) was talking about one man: James Comey, and one organization: the FBI. I don't see either mentioned in your reply.
It's not stated anywhere, but it's Haskell. Usually a safe bet when presented with a functional programming language that is not lisp-like normuses a c-like syntax.
sanderjd: Your comment (sibling of this one) appears to have been moderated. I suspect it's because of your use of is.gd.
No X10 integration?
Can you please share a link where I could find all government APIs? If there is none, can you tell us more about how to get the APIs?
I love c9.io but I don't find a it practical to actually write code on my tablet. I know that was the example I used so I apologize if that made it confusing.
My life as a serial killer’s daughter
H2O – an optimized HTTP server
I strenuously disagree with this article. In my opinion, programming is better compared to writing prose than plumbing.
The US loved Saudi oil, not Saudi money so much. The US never really needed money from Saudi Arabia. The sole reason the US took a distinct interest in propping up the monarchy was for oil price and supply stability.

With the US boom in shale / fracking oil (and Canada's coinciding oil boom), Saudi oil not only matters less by the day to the US, but Saudi Arabia is increasingly becoming a hostile oil competitor looking to fight the US domestics for market share. That conflict will get worse by the year going forward, likely eventually ending with the US reducing its guarantees of security for the monarchy and with the Saudis turning increasingly to China for protection.
Bitcoin Startups May Get Transitional License in New York
How Tyler Durden helped me become a successful entrepreneur
Semi-OT: what is it with all the old-school Linux hackers and their obsession with Google+?
Presentation slides at HTTP/2 conference by the developer.
See also: https://news.ycombinator.com/item?id=8342131
Every time people defend the GIMP for having a terrible user experience (just take it as a lemma; it's been debated to death elsewhere and would just clutter up the joint), they seem to inevitably trot out "But but but the GIMP is for serious image manipulation and photo work!".

You had one job, GIMP. One job.

:(
I have the Dell UP2414Q and it is the best display I have ever used!

The colors are fantastic as each unit is individually calibrated and checked at the factory.

The size of the screen at 24 inches is just right - any bigger and I don't think it would be comfortable for me to use. (for coding primarily) This was the smallest 4k display I could find available at the time.

There is only 1 slight problem, the monitor needs to be in DisplayPort 1.2 mode in order to run at 60 hz @ 4k resolution - and 60 hz is required, otherwise the mouse will feel jerky, even though I have a i7 4790 CPU and GTX 780 TI graphics card.

The problem is when in DP 1.2 mode and you run a game that uses a lower resolution, the image won't scale to fill the screen. It took a long time (and a lot of frustration) to figure it out, but you need to drop down to DP 1.1 mode - which drops your 4k Windows desktop refresh rate to 30 hz - and then the lower res will scale to fit the screen.

It is annoying that you need to do this, but at least it can be done on the fly, ie. about to play a game, then go into the monitor menu and disable DP 1.2, then run the game, no need to reset the computer.

Once you are in DP 1.1 mode, games will run full screen at lower resolutions up to 60 hz. Obviously this monitor isn't targeted at gamers.
Andrew Wiles would like to have a word with you regarding this claim!
All of his comments are rants against women/minorities (including admitting not hiring a female programmer because her resume had too many mentions of "women") and complaints about google banning his adsense account for fraud.

I'm sympathetic to the "faceless shareholders are poisonous" argument as well, but...yeah. It's hard to differentiate neoreactionaries from trolls.
In the end you can't have both. If you work all the time your interpersonal relationships with suffer. The original post is asking for advice in a situation where he is unable to spend enough time away from work and appears to want to keep a lady friend.
Welcome to a corporate environment. If you know how to navigate the red tape, you can get things done, if you don't then you'll leave for greener pastures.
People ran him off because they thought it was a group of people with a nefarious purpose. Since he was so knowledgeable about so many things, they just assumed he couldn't be one person. And of course, any time a group of people are on reddit that spell bad news, right? </sarcasm>