skysight-inc/HackerNews huggingface dataset:
This article doesn't seem to consider the alternative hypothesis very seriously, so as one of the biohackers Ed is no doubt referring to, I'll do my best to summarize why it's not unreasonable to act before all the data is in.

Our knowledge about the microbiome is similar to our knowledge of nutrition: we don't know enough to claim optimality, but we do know enough to say that the modern default is bad.

My product is the microbiome equivalent of the paleo diet -- it simply restores non-pathogenic microbes which were the unintended victims of widespread food sterilization. In our (admittedly small) pilot study, over 90% of people felt this helped their digestion.

I believe this approach is more cautious than continuing to eat a modern diet. We didn't evolve eating sterile food.

http://www.generalbiotics.com/probiotics
We're glad you like it! Thanks for the support.
I've had Comcast native for a while too. Impressed that it just works. Even more excited that I can request a prefix delegation.
Respectfully, I don't see how this is actionable for me as an individual. Ok, I'm not stigmatizing people with mental illness, now what?

I still have hundreds, if not more people, with mental illness roaming downtown, living on the streets, regularly leaving feces on sidewalks, screaming at passerbys and expressing what appears violent behavior and nothing is being done about it.
You can't subnet a /64. This RFC [0][1] describes the IETF's thoughts on why allocating a block larger than /64 is to be strongly encouraged.

[0] https://tools.ietf.org/html/rfc6177

[1] Particularly, see page 3
That was a great read for me because up until about halfway through I had just assumed based on the title that it would be about some kind of long running scandal facilitated on reddit.

It was a really great surprise that it just kept getting more and more positive. I wish more exposé style pieces covered positive stories like this instead of just stories on scandal, crime and corruption.
Of course you're gonna have a ton of wantrepreneurs in LA, it's LA after all and people like to do things that are cool, fashionable, hip; saying you "have an app idea" or are "starting a startup" is becoming commonplace. And it's always becoming increasingly annoying when meeting people and trying to have a conversation of substance. I can't count how many seemingly bright (and average) people I've met who have another idea for a chat app. Enough.

Additionally, you'll notice a ton of media/marketing/e-commerce in LA as this is what the culture really revolves around here. You won't see much enterprise or biotech as you would see in the Valley or San Diego, respectively. Social is also popular since kids these days love the idea of "build chat app, grow user base, raise tons of money, cash out." But most of knows these lottery tickets are extremely rare.

Personally, I don't understand how companies like Nasty Gal or Dollar Shave Club are tech by any means. Rolling out some e-commerce atop en existing platform / site is simply online retail / subscription vs. having anything propriety (they don't) but this is our my problem.

At my company, we do hardware, consumer electronics, software with AI and ML and more challenging issues. Sure, we love to have fun and do things that we enjoy but the whole "start another e-commerce site" is getting real old here. I too find myself in a pickle at times trying to find people in the area who love pure tech and can discuss and play around with things that matter. Way too much "biz dev" idiots here who think a blog is the next tumblr.

DM via Twitter if you want to chat.
I'm in LA. Moved here a year ago from SF. If I had to put a number on the difference, I'd say LA has about 20% the tech activity that SF has. Totally unscientific.

I base this on attendance at meetups, activity at co-working spaces, average skill/experience level of engineers I've met, and companies I've come across as a consultant.

Santa Monica, Venice and Pasadena seem to be the activity hubs.

I will say I have come across a whole lot of non-technical people looking for technical cofounders. That exists in SF as well, but much more so here (also completely unscientific).
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High-friction pads do indeed make fine movements difficult--with a very gentle push, your fingertip doesn't move at all, until it overcomes static friction and jumps several pixels.

I found a trick to get around that a while back: When small movements are needed, don't slide your finger but roll it. No friction involved, that way.
Permutation City was completely unlike anything I have ever read. I love Egan's works and couldn't recommend them any higher!
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The most interesting use of setjmp/longjmp I've seen is in QEMU, which uses them to implement coroutines.
It's not capitalism that's gone off the rails ... it's socialism. All of the countries with slow growth and growing inequality have heavy-handed socialist policies in place.
AFAIK, it's customary to assign a /64 to each machine, and the last 64 bits are used for other purposes (usually the MAC address I think?).

https://en.wikipedia.org/wiki/IPv6_subnetting_reference
Yes, it does, but individual IPv6 addresses are not directly comparable to individual IPv4 addresses, because protocol mechanisms assume that every network ("LAN") segment has its own /64. For example, IPv6 stateless auto configuration (for automatic stateless address assignment, another central innovation of IPv6) only works with a /64, so you can't use it if you have to subnet a /64. As far as the RFCs are concerned, a /64 is the minimal allocation that is used for a network segment, anything else is a hack.
Well, yes. As more of the money is used to make more money, instead of things, experiences, or people... It losses it's correlation with the things that we actually want out of an economy. Plus, those in power (rightfully) use the power to get more power of the sort they already have. According the history books I read as a kid, this is what caused capitalism in the first place (english barons with more money than power using that money to make more money) and the (serial) French revolutions (aristocrats with more power than money using that power to gain more power).

I note these bits in particular:

"After a financial and banking crisis, the first order of business is to clean up the banks, and to do it quickly and radically. Institutions that are not viable need to be shut down while the others should be provided with capital."

"Their central thesis was that the key to [Western] success was not climate or religion, but the development of social institutions that included as many citizens as possible..."

I'm also reminded of a good article on what Iceland did after the collapse - I'm having trouble finding the article, but part of it was that, instead of taking on the debt from their collapsed banks, they issued arrest warrants so Interpol could chase down the executives. (The initial government was going to acquiesce and take on the debt, and that's when the "revolution" happened.)

Finally, someone gave me a really good quote a couple months ago: "Death is the way for an older organism to gift it's energy to a younger one." I then note that part of the financial problem is that failing institutions are not actually allowed to die - thus keeping that energy stagnating in the aptly-named "zombie" corporations.
"When one takes a new and unstudied drug, one makes oneself a human guinea pig."
I believe that reflection upon these results is critical to any attempt at raising the economic productivity of a region. It seems clear that infrastructure, education, and business development incentives (even if only in making it easier to found and afford to fail at making a go of a small business) are critical ingredients to economic vitality.
Read the HN Guidelines. They explain what should and what should not be here.
thank you both for these suggestions! Ive been searching to try and find something like Egan. Ill definitely give these a read!
Note that what Iceland did and the idea of clearing out bad capital and malinvestment are actually capitalist ideas, versus, say bailouts and central bank manipulation, which are not.
So you're saying the US isn't experiencing slow growth and growing inequality?
Perhaps we're using different terminology, but it's absolutely not customary to assign a /64 to each machine.

IME one advertises one or more /64's on a given network, then (either through DHCPv6, or SLAAC [or both]) machines attached to that network acquire addresses within those spaces.

These machines will have a XXXX::XXXX/64 address, but that just means that they're attached to a network that advertises a /64, not that that machine has been assigned an entire /64 for its use.
Did... did you read the article? You may be correct about the correlation, but a) I'm pretty sure you're not and b) the article goes into moderate detail discussing the mechanisms involved, most of which would also be expected to create an appearance that matches what you describe: More socialist countries, by virtue of NOT sustaining zombie banks, have less growth than less socialist countries which ARE sustaining zombie banks, and thus continuing to create the appearance of growth - but it's no more growth today than it was in the years leading up to the collapse.
Nothing a little more government intervention couldn't solve, comrade.
Yeah. I'm, to a decent degree, a fan of calling what we have today "corporatism" rather than "capitalism".
I've had friends mention that they liked Neal Stephenson's "Cryptonomicon", except for the lengthy digressions into mathematics. One day, I'll get mad at them, and get revenge by suggesting an Egan novel.
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Growing inequality by what measure? Gini co-efficient? If so Sweden has a much higher inequality than most of the EU.
On the other hand, if you want to do something else in addition to a prime sieve than some sensible advice on tooling can save a lot of grief down the road. A couple of years ago I decided to learn Ocaml but never progressed much farther than writing a couple of Project Euler problems. Recently I decided to relearn Ocaml with the Real World Ocaml[1] book and, in retrospect, one of my favorite things about the book is their recommendations on tooling[2]. The improved REPL and the vim plugin they recommend are the sort of thing that make learning the language and its libraries much more pleasant but are also the sort of thing I wouldn't think of installing on my own if all you told me to install was the compiler (which kind of explains why I never went very far in my previous attempt at learning the language).

[1] http://realworldocaml.org/
[2] https://github.com/realworldocaml/book/wiki/Installation-Ins...
It really bothers me that some network admins choose to drop all ICMP traffic.

I wish that the Shields UP! crowd had sent the message that ICMP is a very important part of IP signalling; rather than sending the message that eeeevil hackers might discover your network and Hax your Gibsons, so you'd better drop everything you can on the floor to throw them off of your trail.
Drug use/possession is not illegal in Canada? When did that change?
So I can't speak to the specifics of the startups you're referring to (I don't know who they are), but I will say I'm very surprised to have read this.

The responsible development of new therapies is almost always a good thing. I'm confused to hear you say they're not FDA regulated, since the FDA is very clear: if it's intended to treat a disease, it's regulated. Perhaps you could explain what I'm missing?

Also technical note: these microbes are not unknown/uncultured/unsequenced. See MetaHIT, the Human Microbiome Project and the American Gut Project you mentioned.
What does it mean to "request" a prefix delegation?

I know that they use DHCPv6-PD to allocate v6 blocks to end-user networks, and that you can (on residential service) request blocks as large as /60. Is there something more going on?
IIRC, there's a setting in OS X to make it act like a traditional one- or two-button touchpad, i.e. it only recognizes clicks if your finger is in the appropriate place.
$10,000 per person? That's more than a third of the annual income per person for that state. Wow.
Factor is general-purpose and you can write most anything you want at this point.

Here's tar in Factor:

https://github.com/slavapestov/factor/blob/master/extra/tar/...

For untarring the linux kernel, Factor tar beats /usr/bin/tar on my Mac by 1s, but 30s vs 6s on Linux for some reason. Could be SSD vs spinning disk, or worse i/o code on Linux. Funnily, there are about 10 files that differ in case only, and Mac file system is case-insensitive by default, so you can't even untar the linux kernel correctly.

Here's host using the dns client library:

https://github.com/slavapestov/factor/blob/master/extra/tool...

https://github.com/slavapestov/factor/blob/master/extra/dns/...

I wrote it because gethostbyname is blocking and Factor has nonblocking i/o for everything else.

There's a cross-platform disk usage tool that outputs the same stuff as df but works on Windows too:

https://github.com/slavapestov/factor/blob/master/basis/tool...

USE: tools.files file-systems.

There's a high-level library for doing whatever you want with unix users/groups:

https://github.com/slavapestov/factor/blob/master/basis/unix...

effective-user-name [ ] with-effective-user
effective-user-id [ ] with-effective-user
all-users

https://github.com/slavapestov/factor/blob/master/basis/unix...

effective-group-name [ ] with-effective-group
effective-group-id [ ] with-effective-group
all-groups

Graphics demo--raytraced spheres using GLSL on a checkerboard pattern, spheres each play their own music:

https://github.com/slavapestov/factor/tree/master/extra/gpu/...

https://github.com/slavapestov/factor/blob/master/extra/gpu/...

The main file that sets up the world and loads the shaders and sound is 130 lines and reuses the game library.
It's pretty much still the same experience. Once plugins that take advantage of the async and when gui's take advantage of the API I'm pretty sure neovim will not just be equal, but far superior.
Your link is broken - there is an extra ">" at the end.
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I'm saying the US has some of those very same policies in place.
Possession is illegal, albeit laxly enforced. Drug use has never been illegal in Canada.
Amazon will sell you audio files, they won't sell them to me. I live in the wrong country.

Amazon will sell me a CD at the same price you pay, plus shipping.

Apple will sell me audio files, at a 30% premium over what they charge you.
But not for people in the city.. SF County is the 2nd wealthiest in the state and gets significant tax revenue from tourists (via Sales taxes, Hotel taxes, etc.).
Push your AppStartup processing into a background worker?

a) https://github.com/HangfireIO/Hangfire
b) http://azure.microsoft.com/en-us/documentation/articles/web-...
As a vegan, sometimes it's nice to eat at a restaurant and not have to go through the whole 20 questions with the server about whether food has animal products. So I may weigh other factors (like service or presentation or how "nice" a place is) as less important than when going to a restaurant with only one or two vegan options.

Though taste is the most important thing to me!
What you really need is a "solution" that is wrong in just one digit somewhere in the middle that everyone would easily miss when comparing.
People used to learn programming by learning assembly language. Here's one example for the 68000:

First page of contents: http://imgur.com/1XCLrsQ

Example instruction description: http://imgur.com/MV6Le34

Hello world: http://imgur.com/5yKJlQ9

Off topic but if anyone is ever in Cheltenham UK (or is prepared to pay postage) I have some old books I want to get rid of. http://imgur.com/AWV9HLn
Ed Halter on the Art of Guthrie Lonergan
And California judges are competent to decide that question how?

Their opinion is nothing more than "if we don't look at it, we can't see it." It is merely a judgement of what will be considered politically correct. That the judiciary considers itself competent in that domain is terrifying.
Thats partly what I'm getting at. When you start down the path of maintaining a real-life identity and a Tor identity, it becomes increasingly difficult to avoid contaminating one with the other.

But I suppose for the original, "read only" purpose of perusing dark markets, Tails may suffice.
Arbitrary-precision integers is definitely one of Python's underrated feature.
With the exception of Amazon, who evidently weren't interested in cooperating, Tivo does a great job of this. You get some Amazon content but it's not the good stuff. For Hulu and Netflix you get unified search and you can do things like come across an in-progress movie in the guide, see that it's available on Netflix, and start watching it right away. I really wish Amazon would let Tivo have a decent app with Prime support.

Edit: Sure enough, as soon as I posted this I came across an article saying that Tivo will be getting Amazon Prime this fall, as well as Vudu. http://zatznotfunny.com/2014-08/amazon-instant-vudu-coming-t...
I started using X240 a week ago. I am usually not a complainer. I concurrently used X220 and Macbook fine. But I could not like the click pad on X240. I think the trackpad/trackpoint on X240 is simply a failed experiment. As someone who is fine with trackpoint or trackpad on Macbooks, I can't see how anyone can like this click pad thing.
I think it's more about Lenovo trying to appear "new" and "stylish", going after the Macbook designs. Cost reduction could also be a part of it. Every other laptop on the market now looks like a Macbook clone.

What they're forgetting is that many of the people who buy Thinkpads actually like the old-school, "serious business" look-and-feel that originated with IBM. They could continue making a model that is almost exactly identical to the X60/X61 (an "X62"?) but with a faster CPU, more RAM, and higher-res display, and I'd bet they'd still have many customers.
So who doesn't?
Similar to the Razer Blade 14, but cheaper, and without the matrix-esque green backlight (just white) is the Aorus XP3+, which is ridiculously powerful and light. The only difference appears to be that it's actually even a little lighter than the blade (1.8kg vs 2.03kg), the screen is not touch based, the processor is a little beefier, it has more memory, and by default comes with 2x 256GB SSD's in RAID0 rather than a single SSD.

And of course it is ENORMOUSLY cheaper. This may differ depending on locality but I bought the Aorus a couple of days ago for 2599 AUD, and the razer with the same storage is 3699 AUD.

I got rid of both my every day carry notebook and my beefy leave it on a desk workstation just from buying the XP3+, very impressed with it so far.
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You'll be disappointed in X240. The buttons for trackpoint are removed in X240. Instead, they made the trackpad clickable. It's a miserable experience. It is simply impossible to use trackpoint with trackpad enabled because you inevitably slide finger over trackpad to register a click. That moves the cursor. Disabling trackpad made trackpoint somewhat usable but clicking the whole trackpad is much harder than just a button.
https://lkml.org/lkml/2009/7/28/373
I wrote 2 games on the Gameboy and Gameboy Color assembly (both running Z80s at 4 and 8 MHz) back in the day and they were great to program on. Loved the simplicity of the machine.
I disagree. It's a negative step - don't do X, for some value of X. OK. Fine. What's next? I asked in search of positive steps.
Well, it does not appear to be actually trying to target large-scale deployments, nor the same areas that Linux targets currently. Seems to be mostly about emulating/reliving old-school computing devices and their systems. So, from that perspective, seems to be more of a "pet project" than a serious one. It's doubtful people will dump their OS of choice for this one unless there is a specific reason.
If that's the norm in the midwest, it's perhaps worth noting that the author teaches at Rose-Hulman, in Indiana (which has a phenomenal reputation, fwiw).
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Why is this on Hacker News? Is this site going to use its popularity to preach about social issues now, like so many other tech sites have? That's a huge turn off for me.
Here's an account of the Fountainhead Project written by Rich Wingerter, who was a programmer working on the project:

http://www.sonic.net/~richw/FHP.html

While searching for this I also found an interesting paper on the Eagle project:

"Flight of the Eagle: The Birthing and Life of a Super-Minicomputer" (1996)

http://www.faughnan.com/papers/eaglecomp.pdf
Yes, but you are making a big assumption that it will be a fair coin.

In the real world. There are other factors that contribute to gender imbalance(Infanticide, foeticide, mortality etc). Plus also note that once the gender balance goes out of balance it continues get worse with every iteration.

So this basically works like algorithm which is continually trying to increase the count of M's above F's.
Wow. A 25% efficiency boost is huge, both for the shipping company and for the planet.

Wikipedia states that 3-4% of the global carbon footprint is shipping. https://en.wikipedia.org/wiki/Environmental_impact_of_shippi...
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