skysight-inc/HackerNews huggingface dataset:
Is the technology going to be affordable ?
I'm a big believer of free/affordable health care and such technology could have a big impact around the world.
Here is the link to the original research.

http://www.secureworks.com/cyber-threat-intelligence/threats...
I agree that better schools would help with this issue and that there is much room for improvement in the american school system, but I think that parental valuation of, and involvement in, education in still essential.
The article suggests Twitter should take a more active role in policing its community, and the author doesn't appear to think "don't engage trolls" is adequate advice... but, really, what position is Twitter in to take an obnoxious person and bar them from the platform?

One can imagine a solution that requires significant effort or cost to create a Twitter account, perhaps involving proof of identity, but how high can you set the bar without putting legitimate users off?

It may not sit well that people can't practically be removed for reprehensible behavior as it occurs, and I get that it can come across like victim-blaming to tell people they should ignore it, but somehow letting someone yell themselves hoarse (metaphorically) without realizing they've been muted seems even more satisfying than giving them a ban page and having them make a new account in five minutes.
And yet the GC pauses are noticable and annoying. It's not game-breaking because Minecraft is just that good, but I doubt it'd work well for other games.
You are correct in the fact that the kidney's are one route of clearance for small agents that are injected. However, these are typically small molecule agents or particles on the lower size range at a couple nms in diameter. To reference a highly sited scientific article from Chemical Rev (Chem. Rev. 2010, 110, 2921–2959), "At 8 nm, observations have been made that hepatic uptake begins to dominate clearance routes, and by 10-12 nm the reticuloendothelial excretion route becomes the dominant route for clearance."

These nanodiamonds range in size from 15-100nm, so the kidneys will not be their primary route of clearance. It is also crucial to note that with any nanoparticle development, coating is a major factor in its biodistribution behavior. Coatings can and have been designed in more recent work regarding nanomedicine that minimize various biodistribution issues.
You mean stock buybacks?

That (and/or paying a dividend) is just what public companies are traditionally expected to do when they have extra cash, (or when they can borrow cash very cheaply, as is also the case now). Companies have basically been hoarding cash since the last recession, I think I've read that Fortune 500 companies' cash reserves are the highest they've ever been, so it's good to see that they are returning some of it to their investors now.
Sorry you feel that way. Thanks for checking us out! Cheers!
both, also for areas such as single molecule imaging
Worth noting that magic and technology are still treated as fundamentally opposed forces in Shadowrun (essence loss and all that) compared to JRPGs like the Chrono games (though moreso in Chrono Cross than in Trigger), Final Fantasy, Phantasy Star, et al. which treat them as essentially the same thing.
No affiliation, except long-time customer, but I always pimp FreshBooks whenever invoicing comes up. They've been around a while and have a solid product.

http://freshbooks.com

Do yourself a favor and check them out if you're shopping for this type of service.
A funny anecdote on the topic. When I worked in WinFS team, folks tried to add new flags in CreateFile API. Turns out, all 32 bits in dwFlagsAndAttributes were already taken, including the hidden usages inside the Win32 subsystem implementation.
By feedback cycle I mean that companies tend to do more backbacks when the market is high. Which seems counter-intuitive, but makes sense because the market is biased higher when interest rates are low. And then company buybacks push it higher.
Why the OS matters (even more) in a containerized world
These nanodiamonds are cheaper to synthesize than what you find current optical imaging agents on the market for.
Please be clear. Do you claim it's misleading that the GCs need at least twice as much RAM to be performant? If so, based on what actually do you claim that the graph I linked doesn't support that? Can you give an example of some system that does better, with measurements etc?
https://hn.algolia.com/?q=https+ranking+signal#!/story/forev...
Google has a strong case to have HTTPS implemented:

It prevents ISPs etc. from being able to profile your traffic, but not Google's, since you're probably visiting a site with Adsense or Analytics running on it anyway.

Through HTTPS, Google is the only one with a profile of your traffic, and your ISP is no longer a competitor to them.
Light projection doesn't go trough walls...
I guess this is just a template site to get them started, as it only has a basic summary of what they do so far and nothing about whatever their USP is. Obviously there are plenty of invoicing and payment collection services out there already, so hopefully they'll add some more details about what makes them special at some point.
But in that case, a leak only has a 5% chance of being something that anyone actually cares about. ("Anyone" here does not mean the overly paranoid bureaucrat that classified it, it means pretty much anyone else.)
that is actually one area of applications we are exploring! I'd love to have a chat with you about it.
Not sure why otterley was down voted. XP is going to exist for a while.

Old android/mobile clients are another case. Mobile operators are moving towards transparent "4 in 6" NAT/encap on their edges. The server would see a layer 3 IPv6 client, while the actual layer 7 client is an old Android/java stack.
The overloading of the word 'disruption' irks me terribly. It seems like everybody wants to be 'disruptive', when all they really mean is 'successful'.

Anyway, Christensen defines 'disruptive innovation' fairly rigorously, and it doesn't seem like their interpretation fits with his. Half the point of disruptive innovations is that, retrospectively, they were ignored and allowed to exist by incumbents for whatever reason, eventually toppling them. If they've been acquired then they're not disruptive anymore, are they?

Would Oculus Rift have been a disruptive innovation if it was left to grow? Would it have upended value networks? Maybe. Is it a disruptive innovation now that Facebook has acquired it? Well not according to Christensen's criteria for 'disruption'. The product could be called a radical innovation, but it's not disruptive.
Thanks for the feedback. We do have scroll effects, but aren't intentionally trying to hijack the scroll behaviour. Are you able to provide some more info eg, browser/os - if you could provide any screenshots to me, that would be super useful: shaun@obvious.io
This is a good starting point from someone who studies language: http://languagelog.ldc.upenn.edu/nll/?p=4487

For fun, let's see if she breaks her own rule in the first sentence of that article.

As if trying to provide a good anecdote to open this very article, one of the students in my Fiction Writing Workshop got caught up in the adverb conundrum recently.

Almost made it, but fucked up at the end there with "recently".
Here are some slides for Cauldron2014 talks. https://gcc.gnu.org/wiki/cauldron2014

There are some pretty cool things going on it seems, like the compile/inject stuff for GDB or libgccjit.
Time Slippage in Fiction and in Real Life
Faster feedback from parallel RSpec tests on CI servers
I think you neglect to consider that not all people are success-minded, that some, even given all the good influence and knowledge and skills, would rather not use that to pursue things that are usually defined as success--except for the very very few who make it as cultural big names.

These people are usually artists, intellectuals and researchers and their priorities are a far cry from money (and sometimes stability.) Some good decades ago they could get by with a variety of part-time jobs and work on what they believe on the side, and live their whole lives this way and be happy (even by the process of life itself, as opposed to goals and results.) Nowadays that's getting much harder to do of course, and people with this mindset are struggling to make ends meet, let alone live in a bustling city. Add to that student debts and all that--I think it's no wonder quality cultural production has somewhat declined in the views of many, especially in comparison to the 50s, or the 70s. New York used to have a bunch of these people, and it allowed artistical serendipity to take place easily, so dense were their ranks. Nowadays living there, for these people, is no option unless you can live with well-off parents.

These kinds of people might be labeled the cultural elite, and historically they have created most of our art, either through making ends meet somehow (which was more possible) or being supported by patrons or parents--hence why I think 'cultural elite' is befitting, they're supported by an elite who tends to be success-minded or power-hungry (or rent-seeking, which used to be way more prevalent), but they themselves are not.

They're somewhat carefree people, the saner of whom also do not need a lot to live on and don't want to raise a family, so those could conceivably live off basic income. I think that would be good for society, because the success-minded people who naturally come to control decision-making and run things around don't seem to care much (or don't grok) that there's this other side of mankind who don't quite fit in what they build. At least culturally these people still get a say, they do shape culture after all, but I'm afraid that's gonna be less and less so, at least when it comes to the masses. The internet helps give them voice, sure, but when those who are like this and have a cosmopolitan view can't afford a like-minded city, we lose scenes and movements and all these beautiful artistic expressions of a time and place and group of people.

In the field of software development, of course, there are many, who usually devote their lives to open source or learning materials and don't really mind not having money (except when it starts pressing hard.) Richard Stallman could well be considered a great example who went on to make amazing contributions for our collective good, and his patron was the US Military. Alas, research budgets are being cut and cut, especially long-term research without sure profitability, and universities are on their way to bankrupcy, and times like that don't look like they're coming back again.
Which project? CTC screening is fascinating. Could you please point me to some good introductory papers/reading?
what exactly is the mechanism of bioaccumulation in cancer cells specifically? Or is this merely an imaging method that will have to be conjugated to, say a cancer-marker antibody?
I remember thinking that their deep pipelines for branch prediction and large on-chip caches meant that fabs were encountering difficulties with Moore's law

It's really a combination of memory latency and pipelining.

Memory latency is absolutely terrible compared to processor speed, and that has nothing to do with Moore's law. It's 60ns to access main memory, which is ballpark 150 cycles. If you have no caches, your 2.5Ghz processor is basically throttled to 16Mhz. You can buy some back with high memory bandwidth and a buffer (read many instructions at a time). But if you have no predictor, every taken branch flushes the buffer and costs an extra 150 cycles- in heavily branched code your performance approaches 8Mhz.

Then think about pipelining. We don't pipeline because Moore's law has ended. We pipeline because a two-stage pipeline is 200% as fast as an otherwise identical unpipleined chip. A sixteen-stage pipeline is 1600% as fast. Why the hell wouldn't you pipeline? Now, of course in the real world branched code can tank a deep pipeline. Which is where the branch predictor comes in, buying back performance.

http://stackoverflow.com/questions/4087280/approximate-cost-...
China Cracks Down on Popular Mobile Messaging Services
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I can't wait to eliminate from my writing such pesky, "tell not show" adverbs as the following:

today, tomorrow, yesterday, soon, then, now, once/twice/thrice/n times, there, here, hence, home (in constructions like "I took him home"), etc.

Honestly, they do nothing.
I am completely convinced parents and culture can influence affinity for delayed gratification. I have watched it happen in both directions. I don't think it is the only factor, but I seems incredibly obvious to me that parents and culture have an effect.
you are correct, this is primarily targeted to disease states with ligands such as antibodies, aptamers, fab fragments, etc.
Angel Investors Can Now Join Late-Stage Rounds On AngelList
I remember the in primary school made their own sign language. Annoyingly we boys were left out of the conversation for a long time as they denied to teach us.
All 986 bytes of it.
Chatroulette founder would be a suggestion for non-US founders. I heard his site makes 100k per month from ad revenues.
Proof that web servers serve static content insanely fast and efficiently. Would be a smaller memory footprint using nginx.

UPDATE: And it appears to have gone down. Foot in mouth!
Location: Berkeley, CA

Remote: No

Willing to relocate: Within Bay Area

Technologies: Ruby, Javascript, Java

Resume: Upon request

Email: axelrod.jeremy@gmail.com

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Personal Site: http://jeaxel.com/

My passion is in design, which means I want everything I make to be optimized for usage by other people. I create code that is modular, readable, and extensible, and design interfaces that are intuitive and easy to use.
I expected to find the article silly, but I found it pretty solid. I think each point it makes about adverbs (as it applies to fiction writing) is pretty convincing. For example, adverbs often do "tell" instead of "show."

I think the rule is overstated. It shouldn't be "never use adverbs," but "review every adverb to see if it can be improved."
Looks like the smaller but less accurate version of this:
http://www.extremetech.com/extreme/100395-mit-can-now-see-th...
Web users strike me mostly as naive idiots. It's like they suddenly looked up and are shocked, shocked! that all the free stuff on the internet they enjoy: high quality journalism like nyt or verge, gossip like gawker, games, free email + calendar + video services, free chat, free social network services, an excellent search engine, and on and on and on, actually required money to build and run! And that the companies involved are going to go to great lengths to earn as much advertising money as possible. You have to seriously be an idiot to think that all these companies building services that end users don't pay for aren't making money off the end users. Users had to choose between privacy/paying for things and free stuff, and they clearly chose free stuff.

It's definitely not the choice I would have made, but I got massively outvoted.
Yes, and I believe that's loosely covered under the blanket of reciprocity systems in anthropology.
Also the locative adverb "up".
The blog’s top ten most popular posts July 2014 from The Ancient Art of Bonsai
It's quite amusing that this seems interesting today. Apache works on really old, slow hardware quite well. E.g. here's Apache, MySQL and PHP for AmigaOS: http://www.amigaos.net/software/77/aamp-apache-mysql-php

My first job was an ISP I co-founded. In retrospect, the biggest mistake we did was over-investing in hardware, by buying two 120MHz Pentium servers when we could have gotten away with 486's and a leased Cisco access server or two.

But those two 120MHz Pentium servers with 128MB a piece, between them served up dozens of corporate websites, handled 32 dialup connections (we had a horrific setup with Cyclades serial port multipliers wired up onto a large wooden board with US Robotics Sportster modems wall mounted - the Sportster were cheap consumer grade modems prone to overheating, so stacking them in any way was generally a bad idea), ran a NNTP server with 30,000 USENET groups, mail for all our customers, and shell access.

We got 5-6 25Mhz or 33MHz 486's with 16MB RAM to use as X servers, and ran all the clients (Emacs, Netscape and a bunch of terminals was a typical session) on the two Pentiums.
This is an article about designing and developing for Firefox OS. This is not an article about competing with Android and others.

Discussion about which is a better option for the consumer is a very valid discussion and is important to the long term survival of the platform. But, in my opinion, it just doesn't have anything to do with the topic at hand.

It's like if there was an article about a release of the next version of Android and someone came in taking about how the smaller subset of target screen sizes in iOS make it a better platform to design for. Its a valid discussion, but just doesn't have anything to do with the topic at hand.

The "astroturfer" comment is because I can't see any sane reason, beyond self interest or possibly just to troll, why anyone would bother to hop into a thread and just say Android is better when there was no mention about Android in the article at hand.
Singapore Hotel Rooms F1 Night Race 2014 YouTube
> I'm a Freemason.

Then you ought to know the difference between a disclaimer and a disclosure. (But don't feel bad, almost no-one else here does either...)
Always nice to see new apps. As it is free and (?) Ad-free: any chance of publishing the source? Or a "making-of" blog post?

I see the Android version is a whooping 32mb... : / I suppose it bundles a run-time of sorts? Why does it ask for permission to access files and photos?
Hidden defects linked to small-aircraft crashes over five decades
If they are in fact small enough to escape via biliary excretion, that would be great. But just skimming the literature it looks like they can accumulate and persist for weeks in the liver—a situation which would suggest hepatotoxicity is another problem (Zhu et al 2012 in "Theranostics" -- never heard of that journal but paper looks 'ok').

Coatings won't help this problem unless you can somehow change the shape of the crystal to fit through the slit OR get it to cross into the renal luminal space via transcytosis or excreted more efficiently in the biliary tree. All difficult propositions.

I really hope novel techniques like this work but this particular on seems very problematic. If I were you I would complete a serious set of toxicity studies very early on to make sure this isn't a fish that's dead in the water.

Edits: clarifying the points
> We got 5-6 25Mhz or 33MHz 486's with 16MB RAM to use as X servers

But did those have Turbo buttons? If so then you were clearly cheating.
While that's technically true, XP doesn't enable IPv6 by default, so virtually no one uses it.
Uber is one of the few startups that I would call legitimately disruptive, because it uses technology to take customers from the legally regulated taxi industry. Airbnb and Aereo are also what I would consider disruptive. Tesla Motors perhaps.

I think that whether local governments have passed or tried to pass legislation banning a given startup is a good litmus test for how "disruptive" a startup really is. If your startup doesn't have any serious legal challenges thrown in its path, it's probably not very disruptive. The first thing incumbent corporations will do when faced with a legitimate threat is use their political influence to try to make the threatening business model illegal.
Not probably what you were going for, but http://www.math.uah.edu/stat/data/HorseKicks.html has an interesting backstory, to do with the development of Poisson distributions.
Agreed, for now. Caveats TBD. In particular issues of access (e.g. astrocytomas, non-metastatic bladder) and identity (what does it mean to be a CTC? A known driver mutation? We know that some tissues are littered with such mutations...)
Not necessarily. The other 95% (as evidenced by Manning's leaks) often contain information of importance to commercial enterprise -- information that should likely be of public record anyway if it's being communicated through publicly funded channels.
Yeah it's funny how much I overthink these things myself. I would really rather everyone was earning a good wage and tipping was an actual gratuity rather than a requirement to let the barista make rent. Leaving 15p in change at the bar in the UK, as I understand it, is a totally normal and friendly thing to do, but no one will think ill of you if you take it, either.
I work in InfoSec and it is mind-boggling to see the sophistication levels of some of the Bitcoin heists, like this BGP incident. When was the last time you saw a BGP attack? 99.9% of real-world attacks don't even bother targetting such a core routing service. Another example: in March 2012, internal Linode management infrastructure was compromised to steal 47k BTC: http://blog.zorinaq.com/?e=67 http://www.theregister.co.uk/2012/03/02/linode_bitcoin_heist... This means attackers had effectively root access to any Linode's customers' VM! When was the last time you saw an entire cloud provider environment being compromised?

I like to see it as ISPs and cloud providers increasing their security and patching vulnerabilities thanks to Bitcoin's growing adoption :)
Why Aren’t More Americans Atheists?