skysight-inc/HackerNews huggingface dataset:
How about this? I see a lot of breaking news websites (or blogs that post a story whose details they "update as details come in" have no way (ok, maybe I just haven't come across it) of retaining their readers - a way to subscribe to subsequent updates. So that means busy Bob will either completely forget to come back to the story letter or that he will search for the story again and go read on a competing publication.

So maybe a way for people to subscribe to these "developing stories"? An example implementation in WordPress would be that it adds next to the publish button a checkbox for indicating that this is a developing story. On the user end, all such posts show normally but with an email input and relevant messaging informing the user that the article will be updated as details come in and that they can be notified of them.
WiFi device breakdown at YChacks
This is awesome. I've been searching for a SaaS chat widget like this for years.

Any ideas on pricing?
This ignored the fact that the company which develops a successful drug is also developing drugs which will fail. That costs money too, and the successes have to cover the failures.

That said... pharma companies are pretty greedy entities. I know a certain ex-pharma rep closely and she's no fan of her former employers. I can dislike the greed, but I can't blame a company for trying to make a profit.
I think the reason why Gilead's drug is causing such an uproar is because it is worth the money, yet governments are tired of healthcare costs always going up.

A short summary of the issue: In the past HCV had terrible treatments. You would have to take interferon (makes you feel like you have the flu) for 8-12 months. Plenty of patients took their chances on their disease not getting worse. Even if you stuck it out, the cure rate was maybe 50%. The total cost of therapy? Around $80K (for most patients, others were much more expensive).

Gilead comes out with a wonder drug Solvaldi (it truly is revolutionary). You still have to take interferon, but only for 12 weeks. If you do tough it out, there is a 90% chance you're cured. The price? A little more than than the $80K of the previous treatments.

Honestly, if you think about it, for a little more money, society is get a much greater benefit. So what's the big deal?

Well, because this drug works so well and has much better side effects, all those HCV patients who before said "I'll wait and see if HCV gets worse" are now saying "cure me!". There are millions of HCV patients in the US, so if we tried to treat them all right now, it would bankrupt the system.

I can tell you exactly what will happen with Sovaldi and the newer drugs being launched later this year: governments and insurance companies will say "no, unless you are very sick, you're not getting this drug". It will still cost the same to cure everyone, but it'll just take longer.

Now, if you were Gilead, what would you do? Especially if competitors were coming? I know what I'd do, I'd go to Medicaid and Medicare and say "lets make a deal, I'll give you 50%, 60%, 70% off if you agree to let everyone get treated this year". The gov't would have to pay out a lot in one year, but they'd be getting a deal and Gilead would get their return.
It's hard to come up with concrete numbers, but here's a unscientific survey I did: http://www.tokyodev.com/2014/02/13/japanese-developer-salary...
The cycle of greed wasn't needed to develop the polio vaccine. This was publicly funded, historically more advances in medicine are made by people interested in science and the public good rather than corporate profit.
It is exactly for this reason my next laptop will be a MBP running Linux (I have zero interest in MacOSX).

I bought a mid level Vostro a while back and it is absolute piece of shit.

Touch pad detects my palm from across the room but is inaccurate when I actually touch it, screen is mediocre and lets dust in constantly, keyboard is mushy with no positive click.

The spec looked good and Vostro's used to be ok, the Vostro 1700 I had prior was a fine machine.

It's so bad I've found myself using my ancient Thinkpad (Celeron M) when I have to do a lot of typing.
The headline (not the hn title which is the subtitle of the article) is really over the top.

The conclusion that "the brainy" have moved to cities at any different rate then the general populous is in no way supported by the source paper. In fact it states explicitly that historical figures are just the only people we have good data for and implies they represent patterns in the population as a whole.
There is nothing stopping the gov't from doing that right now. Unfortunately, most of the drug development efforts by public entities have had a really poor track record.
Life In Occupied Palestine
What about laser printers?
Here is a nice and deep analysis of Prince of Persia narrative: http://www.thewhitereview.org/features/turning-the-game-arou...
For the time being we are going to keep this completely free to gauge interest. At some point we would likely charge, but at this point don't have solid plans about what the pricing would look like. Sorry I can't be more precise.
Those would probably have existed by now, without the terror.

As I've read about it:

People were commuting from both the West Bank and Gaza into Israel to work, before the terrorism got too bad.

People in Israel used to go with their cars to have them fixed in Gaza. And so on.

After the Intifadas stopped all that, Israel had a depression. And had to start to get more work force from somewhere where they weren't taught with their mothers milk to hate Jews.

A bad loss for everyone. (And insane from the outside viewpoint, where these cultures look quite similar.)
Do you guys know about https://chatango.com ? It's a more mature product, also based on Go backend. Founder here, so please ask any questions.
And if this is such a good idea, why shouldn't it have been done earlier? That would save us another tiresome discussion, for this drug would have never been developed.
You raise a good point. Wonder drugs such as Lipitor are now in the public domain. You can go to Walmart and get a Lipitor Rx for $4/month.

Millions of lives have been saved (and will continue to be saved) by drugs that are now in the public domain.
Apple kept Carbon (the OS9 to OS X transitional bindings) around for so long because of Photoshop and Office.

From personal experience, I can tell you that this does not happen with big software. Apple released the first Intel Macs in early 2006. The next year Intuit released Quicken 2007 which was PPC only.

The first version of Quicken to be x86 for Mac was Quicken Essentials 2010. First of all that's four years after the transition. Second, Quicken Essentials was crippled. Here's a quote from Wikipedia:

> Some of the features of Quicken are not present in Quicken Essentials for Mac, such as the ability to track investment buys and sells or to pay bills online from the application.

So unless you wanted something ultra-basic you were screwed. Intuit's answer was that they'd give you a free copy of Quick '08 for Windows. All you needed to do was buy Parallels (etc.) and Windows.

This was a big problem because OS X finally dropped PPC emulation support, called Rosetta, in 2011 with the release of Lion. So after 5 years Intuit, a VERY big company, was unwilling to update their software or provide a real equivalent for their Mac users.

If you look at the announcements for each version of Adobe Creative Suite for Mac you'll find references to starting to use features of the OS that Apple introduced years ago.
Thanks, turns out I've had the wrong maths for this in my head for years!
Do you guys know about https://chatango.com ? It's a more mature free product, also based on Go backend. Founder here, so please ask any questions.
Shameless advertising much?

Also joined 2 mins ago.
Haven't heard that term before but I live in a farm house at the base of a wilderness range in the northern rockies if that counts.
Making money: How to start your own currency
Did anyone else notice the last two paragraphs which basically said "oh by the way, competition is already here, so this is not a long term issue, and costs will rapidly decrease.". Which basically defeated the entire hand wringing nature of the article!
You should check out this Kickstarter: https://www.kickstarter.com/projects/753230753/packed-pixels...

They're making a portable high res multi-monitor setup that looks like it might suit you.
To all those pulling out pitchforks and torches, how do they think these drugs get discovered and more importantly, proved safe and efficacious for a given human disease?

Do they have any idea how much it actually costs? Sure, the Shylocks in "management" are greedy for their pound of flesh (and which industry does not have those?), but there is a genuine cost to finding these chemical/biologic agents. The days of Alexander Fleming and Jonas Salk are long gone. Just as the days of one-off genius chemists/physicists/mathematicians/explorers now exist only in history books.

Original research & discovery, that is not of mere academic interest, that yields actual usable products, that people can put inside their bodies, is a non-trivial investment of manpower and resources that carries excruciating risk. This ain't some app you can write in your jammies, that can be MVPd by Tuesday and pitched to VCs over next Sunday's brunch.

As to the public funding of such endeavors, that is a subject for another post(s), requiring a larger keyboard than the one on my smartphone :P
Hehe built something like this as a small project a while ago for fun...interlude.im
> I wonder how long before someone gets the bright idea to claim eminent domain on drug (or other) patents for the sake of medicare

Before doing anything that radical, why not repeal the ban on Medicare negotiating drug prices? The "Medicare Prescription Drug, Improvement and Modernization Act" of 2003, which created the medicare prescription drug program, explicitly prevents Medicare from negotiating prices with the drug companies. The drug companies and the insurance companies decide the prices, and Medicare is stuck with that. This is one of the big reasons Medicare pays a lot more for drugs than the VA does--the VA directly negotiates with the drug companies the prices it pays.

There have been attempts to fix this. The House passed a bill in 2007 to do this, but Senate Republicans were able to stop it there. 6 Republicans joined Democrats in supporting it, but that was not enough to get the 60 votes needed to end debate, and the Republicans were ready to filibuster it if necessary. (They really hated it. Senator Cornyn of Texas said it was "a step down the road to a single-payer, government-run health care system"). President Bush promised a veto.

President Obama made repealing the ban on negotiation one of the key points of his campaign for 2008, but had to drop it from the ACA to get drug makers on board, and since then there has been no chance of getting such a thing past the Republican House.
I realise that it's nice that it'll give you a single function to dump whatever file format into (while actually running it through a shell command in the backend), but it's not that hard to:

out = ""
pdf = pyPdf.PdfFileReader(stream)
try:
if pdf.getIsEncrypted():
pdf.decrypt('')
for page in pdf.pages:
out += page.extractText()
except NotImplementedError:
# Yeah, this ain't happening
A similar and fun boardgame is RoboRally: http://boardgamegeek.com/boardgame/18/roborally
+1
That was my first thought too. I had to check the date when I reached that.
Hepatitis C is a nasty disease that primarily affects people on the fringe of society. Many of these people don't have money, they don't have insurance, they often aren't good at sticking to complex drug regimens. And yet a bunch of pharma companies put in big money to develop a cure - not a treatment that makes it manageable, a cure. These drugs are a bargain and we should all be amazed and thrilled that this has happened.
I wish I could work on weekends
The dreadful weekend is always so long. I rarely get out of my apartment and when I do it's either to buy groceries or booze.
I feel that although I might be productive as a software developer, I'm not being productive as a late twenty guy.
It's easy to say go out meet people, but it's so difficult to make new friends at this age. Very few places to go to meetup people. The idea of pub sucks and meetups are there but are boring and it's a part-time thing for everyone. Everyone has a life and here I'm with no life it seems. So what should I do.
I have been thinking about may be starting my own project and seeing where it goes. But I don't know what's the best path.
There might be lots of things related to IP or other things that might come into play if I start working on my own thing during weekends. Could I work part-time and take two jobs ? Why aren't companies open to this idea that a person can work in two places ?
More shameful as it's hijacking it.
Technology is good, the human interface sucks.

How about a Google Glass-esque helmet indicator?
The necessity of truly independent reproduction diminishes when the researchers/engineers can supply an implementation that does real work in real situations. A very high bar of self-evidence, if you will.

True reproduction remains necessary to confirm that the stated underlying science is the cause, and not some other variable that might be legitimate and remarkable but undocumented.
iPhone 4 White LCD replacement touch screen digitizer assembly
I'm not aware of any color laser printers whose photo output quality can rival a top of the line pigment printer.
Oh yes I imagine the pharmaceutical industry wouldn't fight such a move at all, would breeze right in.
The problem isn't the JPEG file format, it's the media the JPEG files are stored on. If your child finds an old CD or USB drive of yours 50 years from now, they're not likely to be able to retrieve any data from it (just like you can't read a DECtape today). And the on-line services that you store your photos on today are not likely to be around in 50 years either. For your JPEG file to survive, you'd have to actively keep on transferring it from one medium or service to another.
I don't know. This seems to be the thrust of his arguments:

"By delegating information curation to multiple independent parties with demonstrated domain knowledge and critical ability, I ensure that what I read is not a mere reflection of what I believe."

Seems pretty reasonable to me.

Do you have any specific critique of "Abnormal Returns" and "The Big Picture," the curators he cites?
Diablo had procedural generation for most dungeons, but also narrative.
try S3 - I found it to be extremely performant and inexpensive at the same time. Put a copy of your site there and see how it does. It you're happy with the performance, add Route 53 and change your site's nameservers to Amazon's. Good luck and have fun with this! I put a site up without a lot of previous knowledge and learned a lot in the process.
Whenever I need a second screen, I use an iPad connected to my laptop using Avatron's Air Display software. It works well for my needs.
How do you scale back the number of newly minted JDs? Do you prevent some capable people who want to be lawyers, from becoming lawyers?

Do you support the taxi medallion system, on the basis that it prevents there from being too many taxis?
Yes, I see Linear Discriminant Analysis more as useful tool for pre-processing and dimensionality reduction rather than using it as classifier
> (They really hated it. Senator Cornyn of Texas said it was "a step down the road to a single-payer, government-run health care system"). President Bush promised a veto.

I don't understand why Republicans have such a raging hard-on against universal healthcare. Pretty much every country that has implemented such a program agrees it is a Good Thing and worth funding through new taxes.
Of course they are biased. That is his point. But our own blind spots can be revealed by studying those different perspectives.
Yeah, thanks for clearing that up for me. Obviously, you can't rank 'programmers' on a linear scale, but you can rank programmers that are suitable for your type of work on a linear scale. Also, all of the best programmers have something in common: they're all very intelligent people.

Question #1 is somewhat out of the scope of this question tho, but I'm really interested in seeing thoughts on question #2.
>> If the images exist only as a digital image file, the answer is almost certainly, "No".

Hrm I don't quite understand. Right now just about every important element of modern history is being saved in raw formats, as well as jpegs, pngs, psds and the like.

Are we assuming that a hundred years from now we'll have completely lost the ability to view these images and videos?

London 1970s
https://www.youtube.com/watch?v=bPIaG644jsI

London 1990s
https://www.youtube.com/watch?v=c84k4Tkj6wc

London 2000s
https://www.youtube.com/watch?v=PSTh80Aybjs

In a hundred years we'll lose the ability to view all of this and only physical copies will survive? How are we even supposed to store video then? You can't print it out, and if you burn it to a CD it's just as useless.

Not being able to plug your 40 year old USB memory stick into whatever-magic-future-technology exists is one thing, but there's no reason whatever-magic-future-technology wont be able to run a little virtualized system that can display it for you.

I'd say the opposite. In a hundred years 3d printers would have gotten to the point where they could just make some sort of peripheral on the fly to view old CDs, records, and even tape drives. In the future if you're browsing the thrift store and you come across a pristine CD of Silpheed I bet you could walk into your local 'maker' shop and they'll print you out a Sega CD to play it on.
I've gone through dozens of Coursera classes, 2 edX classes, and two full MIT OCWs. In my experience the OCWs were far superior in terms of actual learning.

A good textbook is actually quite a bit more efficient than Coursera or edX-style lecture videos. The classes on OCW are more rigorous, the prereqs are clear and it's all about the learning. There's no certificate, so the only reason to be there is to learn. Newer MOOCs, on the other hand, are often watered down. Automated graders on programming classes are great, though.
Holy fucking shit is this ww2 era communist Russia? Yea the public good trumps all and I wish the US was more socialized but that is fucking insane.

Some company funds R&D for a product with their own money and sells it at their own price and since we as a society deem it too high we throw them in jail? Yea we need reforms but acting like an extremist doesn't help.
Introducing broken_windows
The cycle of greed is why pharmaceutical companies spend billions of dollars to create life saving treatments.
We're trying to get there! Plan is to make a user-space process that uses Linux network namespaces to intercept the outgoing TCP connections of a subsidiary process (using DNAT) and then send datagrams according to whatever congestion-control mechanism you'd like.

But not there yet -- stay tuned.
Getting kicked out of school is something we need to replicate? Heck no.

You either have the motovation to learn or you don't, but the point of online learning is to let people figure that out themselves. We absolutely do not need some ridiculous system of gating access when we won't need it.
https://github.com/peczenyj/MooseX may be of interest to you then, there was a reddit post about it a few days ago.

To be honest, as a ruby person, I don't really see what benefits it brings to ruby but maybe I am just missing something.
I often wonder if people even read the articles. Yes this drug expensive upfront. Why is it expensive? Unknown. Does its development process justify its expense? Unknown. Is this drug a potential cure versus a lifetime of (more expensive) maintenance treatment? Likely. Are there competitors coming to market soon (as someone else mentioned)? Most likely

Edit: Larger costs spread over the long term are more palatable than lesser costs compressed into a shorter term. Humans are bad at estimating scale.
I started going to the gym to get fit. Turns out there are people there with similar interests. So you end up making friends. They invite you out, or you invite them etc.

Friends and family are important. My point is, its never too late to make friends. Find a hobby which involves other people. You will naturally make friends, and stop drinking and eating by your self.

you'll be happier as a result and stop looking for things to fill your time with. You might even end up laughing and having fun.
Research: JavaScript Testing Approaches
Did you actually file bug reports for specific improvements? I use both heavily and have run into good and bad experiences with each — you have to talk about specific features before you can meaningfully compare anything. Is Responsive Design Mode better or worse than Chrome's debugger? Depends entirely on what I need to do.
Shameless hijacking and also just not as good..
I'll be honest with you, the price of these drugs is not going to come down with competition. Rarely do drug companies ever compete on price. Usually, the only time you do is if you have an inferior drug.

If Medicaid/Medicare were smart, they'd put out a tender when the competition arrives. Go to both companies and say "We're will to buy enough drug to treat 1 million HCV patients, what can you do for us."
Probably because nobody has contacted Synology to report the vulnerability
Just fired up a throwaway to comment here. I've been taking this medication over the past 3 months and finished about a week ago. A test a month ago showed I was already cured. This drug is good. Really really good. Side effects were minimal in my case and absolutely worth it.

I only skimmed the article but knew what it was about right away just from the headline. With healthcare, my copay per month was originally 200. My employer gutted my health insurance midway through treatment and my 2nd and 3rd months were quoted to me at a 2000 a month. I spoke with the specialized pharmacy and told them I couldn't afford that. They got me approved for a program that brought my cost of the Sovaldi down to 5 a month. The secondary medication (Ribasphere) to go with it was a little more expensive, but I forget how much.

Either way, I would have gladly paid the 2000 a month for this cure. Cost wasn't even a factor to me. If it came down to having to take out an 80K loan for it, I would have. My health is more important and the peace of mind knowing I've been cured is indescribable.

I'm open to questions since I've been dealing with this over the past 6 months.
You're totally correct that the performance is terrible when the actual network characteristics are something that the algorithm's "prior assumptions" thought was impossible.

We think the same is true of traditional TCP. (For example, traditional TCP assumes that in-network buffers will be small, and therefore that it's acceptable to keep filling them until they start dropping packets, without harming delay-sensitive cross traffic too much. Today's Internet no longer matches TCP's implicit model, and the consequences are that you can't upload to YouTube and use Skype at the same time on a consumer Internet connection. We think it's better to at least make the assumptions explicit!)

In the second paper (now posted), we have improved the initial results in that we can now train a RemyCC that outperforms TCP CUBIC-over-sfqCoDel over a 1000-fold range of link rates (instead of 10x in the first paper). But the same basic point still holds.