skysight-inc/HackerNews huggingface dataset:
> In France that seems to have been the case until recently, but not any longer

As your source notes, that does not affect "irreplaceable and expensive drugs". Cost-effectiveness concerns are typically about cases such as reimbursement for a generic vs. an equally-effective non-generic medicine.

> Putting compulsory licensing aside, which does not happen in many countries, I don't think this contradicts the poster above - a government agency makes a judgement about the cost-effectiveness of a particular drug, and they either decide to buy or not to buy depending on whether the price is above or below that limit.

Regarding compulsory licensing: contrary to what some people think, Europe isn't actually all that socialist; compulsory licensing exists as an ultima ratio in cases where the greed of a pharmaceutic corporation would endanger access to an important new drug or procedure (which was exactly the case in the BRCA case). It's a Sword of Damocles, not a weapon that's being wielded routinely. Whether the option actually exists is irrelevant: with a government-backed negotiator, it can always be legislated into practice (again, which is what happened in the BRCA case after a firestorm of criticism).

Regarding government agencies making a cost-effectiveness judgement about the purchase of a drug, that's again an inaccurate generalization.

First of all, recall that private insurance companies make such decisions all the time (see the article I referenced above), with the difference that they are interested only in their own bottom line, and that the health of their customers only enters into that calculation insofar as it affects profit or regulations force them to (the latter of which is the exact same situation as government backed-negotiation, except for the lack of the bargaining power of a monopsony).

Second, a minority of drugs are actually monopolies; price a drug for which there is competition out of the market, and you simply put money in your competitor's pocket. Likewise, drug companies don't just want to sell one single drug. Ask for too much for their one new irreplaceable drug, and they may see the income from their other ones go down (there is, after all, only so much money to be had in total).

Third, this is not necessarily how it happens. For example, it may not be a government agency (as in Germany, for example), and the agency may not have the power to make a decision whether to buy or not to buy a drug, but only whether the drug is effective (including relative effectiveness compared to other drugs), especially for life-saving drugs.
Tutorial: How To Install PHP-NG From Source on Ubuntu + Benchmarks
"My $0.02"

Why do people feel the need to write this after their posts? Were you afraid it would not be clear that it was an opinion? What purpose does it serve? Why did you go to such length to write it as "My $0.02" rather than "My two cents", or just "My 2c"?

It seems to be some kind of "thing" that people do here. Is it an in-joke?
> A 32GB iPhone 5S in Ireland costs €799

And includes a two-year warranty package that is not included in the US price.
This is probably the best resource for namespaces if you are also interested in those:
http://lwn.net/Articles/531114/
What do you think about Rohos Mini Drive application?
What do you think about Rohos Mini Drive application? Is it save to store my data on encrypted disk?
Worth pointing at that there isn't a single legal system in the UK - Scotland's system is quite different at all levels from England & Wales (I have no idea about NI).

In Scotland it is 4 years for an LLB (or 2 if you already have another degree), 1 year legal practice and 2 years traineeship - but there is no "final exam". Trainees can start appearing in court at a low level after 1 year. Fully qualified solicitors can appear in Sheriff Court. More serious stuff is dealt with in the Court of Session (civil) and High Court (criminal) - where you need to be an Advocate to appear - the Scots equivalent of barristers. You can be dual qualified as a solicitor and an advocate, although this is fairly rare. Advocates can't represent clients directly, only act on the instructions of solicitors, and solicitors can't appear in the higher courts.

Qualifying as an advocate requires passing exams and then doing a period of devilling to qualified advocates (usually senior non-QCs) - during this time you are an "Advocates Devil" ;-)
How does the JS version affect SEO?
Have you heard of the two process design method? [0]

It makes your port maps super simple (and can change them by editing just one file) and each entity consists of just two processes: one to update the entity's state on clock and the other to generate the combinatorial logic using procedural, not dataflow, programming. When you use procedural, you can step through it with a debugger just like with SW! Makes debugging much easier. Also, using records for the port maps makes the ModelSim waveform viewer much easier to use.

You can see an example of it in a MIPS subset I wrote. [1] Any file with a _r.vhd or _p.vhd suffix is written in the two process style. I'd suggest looking at the ALU and I-cache, they are probably the simplest and cleanest entities.

I like your use of numeric_std. =) I'm surprised by how few times I've seen it used.

[0]: http://www.gaisler.com/doc/vhdl2proc.pdf

[1]:https://github.com/jevinskie/mips--/tree/master/project4/sou...
Map Showing Ratio of Median Software Engineer Pay to GDP/Cap for 50 Countries
>The goal is to try and build a small (and decently reliable) VM from the ground up, learning more and more C as I go.

The author explicitly mentions, he is in the process of learning C while he's building something using it.

This is interesting because the folks at [osdev.org](http://wiki.osdev.org) keep stressing that you must be a god-level expert in C, before you even think of getting into systems programming.
I would say Bitcoin, although my background is a little different to yours.

I primarily get hired to build Web applications which deal with some type of bitcoin payment (no bitpay or coinbase), so it makes sense for me to be paid in Bitcoin.

I'm a Bitcoin evangelist, so I generally pay for most things with bitcoin, so I don't have the issue of converting it to fiat.
Driving digital growth with the Internet of Things
What if you wore a band around your back and sides, that would vibrate at a certain location to communicate angle, and intensity to communicate distance?
A few releases ago, it was also killing (with segv!) whatever process was observing the server with ptrace(), such as gdb or strace. I ended up unpacking and firing IDA; found the routine, and yes, that was exactly what was happening. I don't know if the current version does that anymore.
Wikipedia says: "A closed platform, walled garden or closed ecosystem[1][2] is a software system where the carrier or service provider has control over applications, content, and media, and restricts convenient access to non-approved applications or content."

Google doesn't restrict access to applications or content on my Nexus 5, so how is it a walled garden?
I created this map based on data from Bloomberg/PayScale. For more info on what is displayed click on the i-button (3rd to right) in the top menu or ask me here.
We have this problem at our company where the fastest internet our company can possibly get is 20mbps down/4mbps up - and we make ~20GB of backups each day. Absolutely impossible for us to upload all of it to a server offsite overnight.
Apple needs x86 to run existing apps. Who would accept a a big slow down for a slightly cheaper laptop. x86 intel chips are a RISC design with a glue layer which grafts x86 on the outside. Could Apple design an x86 chip with an ARM RISC core hidden inside? Sounds pretty complicated, I doubt they have a big enough hardware engineering team. If there was an ARM core inside could it be exposed for recompiled software to take advantage of it? Big issues managing state/contention between 2 different ISAs?
For me, looking behind is dangerous, as I will swerve slightly in doing so.
One of the things they mention in the Kickstarter is an open API. I guess that would make it more straightforward to make custom additions to the system.

What I imagined when I read "sixth sense" was something that you stick in your backpack close to your back where it vibrates stronger the closer the car behind you is.
Bitcoin, hands down. Specifically Bitpay You can get paid in 9 different currencies in 33 countries with 0% fees. Zero exchange rate risk unless you want it. Bitpay is especially nice for freelancing because you can issue manual invoices.

https://support.bitpay.com/hc/en-us/articles/201890513

I use Bitcoin, Paypal, and Stripe in my own business and I like Bitcoin the best by far. No charge back hassles, zero fees, no waiting 3 days for ACH payment confirmation.

There is one draw back that I see, that being that right now it isn't quite popular enough yet that it can be your only payment method. Some people are just not going to be capable of using it. That said you would be surprised I suggested it to a parts supplier I was working with who because of their location costs me $110 per wire to pay invoices. At first he told me no way until I told him flat out he was losing business on my smaller orders because even though his product was best on price the very high transaction fees made them more expensive for orders under several thousand dollars. They were interested in it all of a sudden. Funny how that works.
I actually use square cash and it's been great! No fees, it's simple. It's good as long as your pay doesn't exceed the weekly limit. (2500)
Oh, and their examples are weird. I found this snippet earlier on, and it made me go “Huh?”

if(s[0] == '%' && s[1] == '2' && s[2] == '0') // escaped space?

That can read past the end of the string if it ends in a '%'. The length check is missing. Maybe it's not such a big deal here, and this is only an example, but if the author's examples are this sloppy, and we can't see the actual source code of his server, then it's hard not to generalise.
Is there something you particularly like about the Swiss system, or do you like the Bismarck model [1] in general, which they use (as does Germany, France, Belgium, the Netherlands, Japan, and much of Latin America), and are simply using them as a good example of that model?

Frontline did an interesting comparison of the UK, Japan, Germany, Taiwan, and Switzerland [2].

[1] http://www.pbs.org/wgbh/pages/frontline/sickaroundtheworld/c...

[2] http://www.pbs.org/wgbh/pages/frontline/sickaroundtheworld/c...
The lessons from scratchapixel.com were for me the most helpful, they really made all the stuff about colour-spaces "click" for the first time. Mainly this chapter, explaining about the tristimulus, CIExyz and how they transform into sRGB and what is up with that horseshoe shape:

http://www.scratchapixel.com/lessons/3d-basic-lessons/lesson...

Further, if you click around there's a few more chapters relevant to colours that put this theory into practice (in the context of raytracing and rendering):

http://www.scratchapixel.com/lessons/3d-advanced-lessons/bla...

http://www.scratchapixel.com/lessons/3d-advanced-lessons/sim...
Manufacturing mobility solutions are the latest buzz
Amazon has a new Programmer's Bookshelf
There are laws to throw you in jail if you don't buy it from them at $80k and try to buy it from Canada, Mexico or India instead where they sell it for a fraction of the US price.

There are even laws making it illegal for the government to try to negotiate the price for medicaid/medicare.

So why not laws to protect the price?

We can regulate the consumer side but not the manufacturer side of the price?

Don't fall for the illusion that corporations are people and deserve freedom to price things however absurdly when there is a crisis.
Venteo – The events camera app
Show HN: Inrevi – Just reviews
I've attempted - and failed - to establish a US account many times. I've even asked US natives and US banks over here to help, and they couldn't do it either.

I always seem to run into rules abut money laundering, domicile, and all kinds of other bureaucratic nonsense.

If anyone has managed to get past this, I'd love to know what the secret is.
Ask HN: So what do you want in a mobile phone
I've been watching conversations about phones here for years. Most of it is the normal iPhone vs Android debate. Little of it has been innovative.

Recently Amazon came out with the Fire. Reviews here were tepid to say the least. Tizen, by Samsung, seems to be viewed as nothing more than a cudgel. Even in the best comments it's met with Fire-like apprehension.

So what does the community want? Some time ago there appeared to be a small faction of WebOS cohorts. Many panned that idea too. I realize that there is not a single, unified view of phones. I hope that this question provides a touchpoint for startups in the hardware/os space to reference for future ideas.

Thanks.
See this map?

http://www.advisory.com/~/media/Advisory-com/Daily-Briefing/...

If you live in any of the grey areas and don't make enough to get Obamacare, you cannot afford this drug, you will die.

That is 50+ million people. Hopefully only a tiny fraction of those people have Hep C because I feel horrible for them.

They didn't price it $5000, $10K, $20K or even $30k. They priced it $80k. Every 12 people is a million dollars for them.

Then they turn around and will sell it overseas for $8000.

The only hope for people in those states will be to buy a plane ticket to where it will be $8000 for the whole treatment, live there until cured and hopefully come back alive and not arrested for not giving the corporation $80k
I thought about the metadata thing but decided to exclude it for the earliest versions of textract to keep things simple. If you'd like to see it in there and have a good example of how you'd like to use metadata, please feel free to throw an issue on the issue tracker https://github.com/deanmalmgren/textract/issues/
If it took pictures of the plates and drivers of all the cars that pass from behind, it would be a quite useful gadget.

I'm someone who has seen too many Go Pro videos on YouTube, here's an example of such a video, this is a scary video: https://www.youtube.com/watch?v=i556e3qyt58
The Copyright Monopoly Should Be Dead and Buried Already
I also assumed that it was some kind of Python wrapper or implementation of Tesseract OCR when I saw that name.
One would think so when Tesseract being (one of?) the best preforming OCR-programs out there.
I haven't used either in the last year or two, so a lot may have changed, although, in the past, many of the low end parts had a built-in (slow) PCIe Gen 1 block, so only wrappers were needed to use it, no licenses. IIRC, this was (one of) the problems with the Lattice board, because with no built in endpoint, you needed to license an expensive "softcore" PCIe block (or write your own...) The same is true of 1/10/40G MAC blocks.
I disagree. This was the state of things perhaps 1-2 years ago but this doesn't represent the situation at all today.

Using a bitcoin payment processor like Bitpay you have zero exchange rate risk and can receive payment in 9 different currencies in 33 countries.

Coinbases daily buy limit is $50,000 not 10k

You still have the computer security problem when you are using online banking and any reputable Bitcoin company has as good or better security than a bank. Two factor auth, and hardware tokens are the norm. I can't say the same for most of the banks I've used.
For what its worth, textract (python) also has ambitions of including OCR through the tesseract-ocr project https://github.com/deanmalmgren/textract/issues/16
How do you explain the amount of time you dedicate to investigate and attack Bitcoin? Not saying that you are well informed though because most of what you've said is just wrong, but still it's pretty weird if you ask me. Especially when no one is forcing you to use it through violence, unlike other currencies (eg: the currency of whatever country you happen to live or do business in, probably USD).
Technology Amplifies the Contributions of Infosec Pros
I don't think so. Why would I need vagrant on the server ?
~/octohost-cookbook$ sudo rake knife_solo user=root ip=172.16.90.151
rake aborted!
Kitchen::UserError: Vagrant 1.1.0 or higher is not installed. Please download a package from http://downloads.vagrantup.com/.
A friend of mine had the same problem with HSBC moving from Australia to England. Slogan: "The world's local bank". Experience: "Go away unless you're a large business". Their practices actively discourage private users. The branch here in Melbourne wouldn't even accept forms supplied by a London branch, filled in, then faxed by the same London branch office... 'Not original', despite being sighted as original by the London staff, who were the ones doing the faxing.
Any open SSH port will get these kinds of hits.
First, the shark eating people hands is disgusting in the normal, literal sense of the word. I wanted to leave the site as soon as I saw it. I know that the idea is to be funny. There are probably people with a macabre sense of humor. To me, the anthropomorphized shark is down in the uncanny valley. You might lose users on it too.

Second, the fact that I have to create an account to do anything makes this site useless. I've already got accounts on sites that I don't visit anymore, and that I only visited once. I've reached a point that I refuse to get any more such accounts. If a web site is not going to give me at least read access to some of its useful comments, I'm not going to use it.
Assassin’S Creed: Unity Massive Map Leaked Also Character Details
Open up a US LLC via the internets, then travel to the US and open up a bank account under the LLC's name with your certificate of incorporation in hand (this gets mailed to you by the state you incorporated in). Results may vary depending on the state. This is also good in case you get sued, your personal liability is shielded by the LLC unless the corporate veil is pierced.

This is not legal advice.
If I'm interpreting this correctly, this means a median coding salary in USA/Canada/EU is about/slightly below average for the economy, but in the developing world (particularly India) its waaay above average?

This kind of makes sense, although it sure shatters the illusion that software jobs are well paid in the developed world.
This is AT&T really vague article. I take pictures: why shouldn't I have the copyright monopoly for their use. What f someone takes them and are better at marketing (but shitty at taking pictures).

What you are after is the publishers and the labels, not the copyright monopoly.
Could you jump onto a comet?
Linux 3.16 released; Linux 3.17 merge window sucks
It will not read past the string if it's null-terminated.
Don't conflate that sector of research with "mere academic interest", scientists on the public side are frequently even more motivated to find practical therapies.

If motivation alone were enough for scientists, most diseases would already be cured!

Now, how do I know that? Because, I'm one. Currently, my post-doctoral research is focused on structure guided drug design against HIV and Cancer targets, working closely with industrial groups. Other researchers in the group work on Hepatitis C targets, so I'm familiar with challenges. In the past, I worked at a drug discovery start-up on metabolic disease targets. With over a decade in the field, I guess I might know what I'm talking about :-)

But hey! I'm open to new ideas for improvement. I'll be happy to write more if HNers are interested.
Show HN: Hackers News on Twitter
2 English Guys On Holiday in America…Hilarious
All of this while they're supposedly "monitored by FTC for 20 years on privacy issues". What a joke. If anything, the FTC monitoring serves to give them credibility on privacy issues - "if FTC doesn't say anything, clearly they're doing nothing wrong privacy-wise?".

Whatever. I deleted my account 3 years ago and never looked back. Even when I was still using Facebook, I never liked having it on my phone because it was such a bloated mess.
Google On Complexity Of ‘Right To Be Forgotten’
This is a small project to learn Heroku, i mad a script that read HN front page and pass new links to this twitter account
> Remember that a hibernating system is actually in a low power state

Not the original quote. The quote was "even if your device is turned off", which I take to mean 'shutdown -h now'. Nowhere is hibernation mentioned.

If your EFI/preboot environment is rooted by a three letter agency you have more problems than someone getting your picture.
Show HN: Dock, a tool that simplifies Docker for local development
Germany’s Bauer Media launches $134M European startup fund
In case you're interested in reading previous discussion of this,
here is a list of (some of) the previous submissions:

https://news.ycombinator.com/item?id=7400532

https://news.ycombinator.com/item?id=6851475 <- 62 comments

https://news.ycombinator.com/item?id=6821326

https://news.ycombinator.com/item?id=3754697 <- 17 comments

https://news.ycombinator.com/item?id=3121508

https://news.ycombinator.com/item?id=2234878

https://news.ycombinator.com/item?id=1739868

https://news.ycombinator.com/item?id=1499925

https://news.ycombinator.com/item?id=1106502

https://news.ycombinator.com/item?id=312827 <- 25 comments

There may be more.
Hmmm, I may have misunderstood what the OP meant by 10X overdose. If he meant "just" 10 hits of typical street acid (75ug) for most that would be way, way too much, but far from what I was understanding (overdose to me equating to something like 1,000ug, an amount very few would ever take).

re: losing your mind, sure, THC can trigger all manner of darkness, have been on my knees a couple of times praying to get me through it -- hallucinogens can bring the good and the bad ;-)

re: people doing drugs to lose their mind, right, keep in mind the context (10X overdose = 10,000ug). There's losing your mind, and then there's lost your mind.
Welp, I'm outta business... https://github.com/bagrow/datatools
Your best customers can't pay with Paypal

I've always been amused with the creativity that Finance can show if it's in their interests, and the lack of creativity when the issue is irrelevant to them. Having had a long background in support, I must admit that I'm jealous of that political power :)
After months of frustration, I recently set up a way getting paid using credit card via stripe through WordPress. Main advantage: knowing a deposit is paid immediately. For whoever's interested, I did a write up on what I did on my blog:

http://trenvopress.com/2014/08/stripe-for-freelancers/
Article about "innovation" hypothesis - that criminals get domesticated and only use crime as a social ladder.

There is a very interesting comparison of Italian mafia and organized crime today.

When read alongside Ianni, what is striking about Goffman’s book is not the cultural difference between being an Italian thug in the early part of the twentieth century and being an African-American thug today. It’s the role of law enforcement in each era. Chuck’s high-school education ended prematurely after he was convicted of aggravated assault in a schoolyard fight. Another boy called Chuck’s mother a crack whore, and he pushed his antagonist’s face into the snow. In a previous generation, this dispute would not have ended up in the legal system.
Most blog posts about teaching children coding focus on why it would be useful for children to learn to write code. That's fair enough, but it ignores the problem that teaching time is finite - the question is not 'would it be useful to learn to code?' (that's obvious) but rather 'is coding the most useful thing that these hours could be spent on?'.
It would have been better to compare the median developer wage to the normal median wage. But median wages can be hard to get (often you get bullshit like household median wages). Anyway, in the US median wage is a lot lower than average, so the comparison does not really say much there. In other countries the gap is often smaller, but still.