skysight-inc/HackerNews huggingface dataset:
I've done a lot of work on this @ https://www.teselagen.com/

More specifically, we are able to automate combinatorial gene assembly straight from a web app interfacing with a TECAN microfluidic liquid handling robot.

Here's a proof of concept with a simulator, but I've tested this in a live enviornment.

https://www.youtube.com/watch?v=FWA1O0DHEh8
I was also a fan of destroy all software screencasts, and found them incredibly useful in leveling up as a ruby developer. I've recently subscribed to Ruby Tapas http://www.rubytapas.com/, which I find similar to DAS in topic selection and quality.
Linkis.com – Share links and collect opinions
3 steps to approach coding story
No, Microsoft didn't get the patents in the sale: http://www.reuters.com/article/2013/09/03/us-nokia-microsoft... They only have a license to the patents, not the ability to use them to go after other companies. IMHO they bought Nokia because it was on the verge of collapsing and taking Windows Phone down with it. Whether it really mattered is up for debate considering WP's now shrinking market share.
Where is "here"? :)
Why would floor vents be a problem? Existing, manual dampers in floor vents often have the moving parts recessed below floor level. The one extra issue might be increased chance of spilling liquids on the unit.
IBM has traditionally had a lot of very strong research labs including IBM Almaden. That said, they also have a reputation for driving out relations with academics and local researchers in the name of "budget" -- very similar to the overall outsourcing regiment Cringely has outlined.

I'd like to know which of the labs are getting this money and what hiring they are doing contrasted with any downsizing they previously did.
There are other countries around, too.
New Imgur
CodeProject: Implementing a WADO Server using Orthanc
I built a tool around FreeSWITCH to do this in some down time between gigs. Trust was the biggest issue; the 3rd party recording the call hears account information, mothers maiden, secret codes and silly things like this. Trust was hard.
Software optimisation will become important again.
The disconnect is the difference between being hungry and actual starvation. We are so rich that most of our poorest can still get fat on the food they can acquire. The worst of our problems is no longer starvation, but bad nutrition. (to an extent, starvation still must exist somewhere but it is very much less common)

Starvation will always get more sympathy, and the dismissal of this is inappropriate.
I disagree, a lot of people crate massively good work but never self promote. Not that he is self promoting, but the point stands producing high quality work does not mean fame.
How is this different from feedly or any RSS reader?
Many times the actual cutout in drywall is smaller than the "vent" cover, which is mostly for aesthetics. So of course you can make a vent cover two feet long with only the center 50% being the actual vent and the rest being a thin plate that simply sits on the wall and hides the screw holes.
There's enormous demand for good people globally. The price at which demand meets supply is pretty nice for employees these days.
IBM does a lot of basic research.

Intel and IBM have a long standing patent cross-licensing arrangement in place.
Unusable for the data visualizations. There should be a link to the original site.
Yeah I dunno what's up with quantum computing. DiVincenzo isn't there any more.
Also, never forget that there are other companies around.
We should not forget that dinosaurs are actually reptiles, and that they "evolved" from reptiles to birds to adjust to changes and circumstances.

More info here: http://www.mapoflife.org/topics/topic_431_Evolution-of-birds...
Show HN: Enabled Jobs
It would be interesting to get your feedback. I am posting it here, as I first read that article on HN and wanted to see what the community here thought.
Seebeck generator, I assume. Basically stick two different types of metals together and generate electricity when the temperature changes (i.e. every time the central air kicks on and off)
I believe mad cow disease put a stop to commercial use of animal components in feed for animals that will be consumed. I don't know if this applies to insects. When I was a kid we fed burnt chicken feathers to cows.. I think that is outlawed now as well (commercially, I'm sure you could do it for home use).

I think insects to chickens is a great idea though. There are some people that grow mealworms for chickens and I've seen dried mealworms at the feed store as chicken treats.

I had some chickens this year (my first year with them). A weasel got in through a small hole smaller than my fist and killed every chicken at about 9 weeks old. He then took about half of them back out the same hole... in pieces and left the remainder for me to find in the morning. It was a pretty gruesome scene. I set some traps but was never able to catch him.
But before the massacre, I would take the chickens out at night and hold them under the back porch light and they would happily stuff themselves on insects and moths landing on the wall.

I want to come up with an insect trap so as to avoid the trouble of raising insects. They are all over anyway... why cultivate them?

I'm building a better coop and am going to try again next spring.
This can also be useful in unpredictable ways. One is the North Korean nuclear test a couple of years back[1].

"The blast generated infrasonic waves that propagated all the way to the upper atmosphere causing small variations in the density of electrons there.

By analyzing the signals from GPS satellites collected at ground-based monitoring stations in South Korea and Japan, scientists [...] confirmed the ionospheric disturbance generated by the North Korean test."

[1] http://gpsworld.com/researchers-see-ionospheric-signature-of...
Not when the A/C turns on and off, but rather the entire time it is running. The hot side would be exposed to the room, cold side to the duct (and vice versa when heating).
The title of each post links to the original page
> what 'wins' in the cloud is the ability to oversubscribe the hardware

We're increasing compute exponentially, so it makes sense we'd want to over subscribe it as much as possible. Demand is like a dog nipping at your heels.
Why social media needs to manipulate you
Iron Maiden found in what cities there music was being most torrented, and went and played concerts there. This helped curbed the piracy and gain new fans. You could hold movie screenings in a bunch of cities and have a place to buy DVDs and other merchandise.
Article: http://www.citeworld.com/article/2115676/big-data-analytics/...
show me the feedly page for xkcd. :P
search, infinite scroll view, easier time jump makes for better binge reading of comics
Depends if the "real world" is the US, Sweden or, for example, Bulgaria.

In the US, this might be the case. In Sweden, mostly you'll find kids, moms and people studying (depending on the city, if it has a university or not). A very small subset is there for computer access, but it's certainly not a majority.

In Bulgaria, no one seems to go to the library. They check your ID when you go in and it's not really a place to hang out.

Libraries aren't the same everywhere.
Source? As someone who just complained about "many" being a weasel word you seem pretty happy to throw out something you just made up.
An Irish holding company. Actual technical registry operations are handled by Afilias USA, Inc. and subject to US law.
No, that's pretentious' older brother: Elitist.
yclist has a few errors, so not sure if it's all 100% accurate.

To name a few:
xobni - bought by yahoo and now shut down (listed as active)
like.fm - dead, but listed as active
Exec - listed as active, but was bought by Handybook
Bump - listed active, but dead
What's to stop someone from just disabling the light? Can you not jam a pin in it or something?
The comment I replied to talked about psychology, not physiology.

"Simply noting a difference" is never simple when dealing in stereotypes driven by historical prejudice.
It's good to have options. I'm surprised it took them this long to realize it.
(Since I can no longer edit my post:) The link has been updated, and they are now for sale in the U.S.! $129.00
Great, that's really helpful feedback.

I guess the way I see it is that there's a difference between a namespace and a module. A namespace is what you're describing: you want a way to isolate the symbols of different components from one another, but you don't really want ironclad abstraction barriers. A module, on the other hand, is the unit where you really care about presenting a well-defined API. Sometimes projects call for one or the other, or a mix of both. You can always technically model namespaces as modules, but you end up repeating "pub", "public", or "export", or whatever your language calls it a lot. So it may well be good to have both features in the language.
This is a joke, stop spamming HN with link baits.
Magnetic-Core Memory
So what's gained by hardwiring an LED versus forcing it via software? The stuff I saw has a front light fairly clearly.
Implementation details. My point was really, it's not secret sauce.
Teselagen is cool design software but there's a whole other side of the equation.

I don't see any microfluidics in that video, unless one of those reservoir blocks or plates is actually something else?

You know that's pretty far from really automating combinatorial gene assembly :p You need a lot more than a Tecan to do that kind of cloning; even just the assembly reaction (Gibson?), which is the simplest part is going to be better off in a thermocycler or incubator compared to a warmed deck block. Tecans are pretty unusable at volumes below 2-3 ul, too, so setting up the reaction isn't always straight forward, especially if you need to e.g., PCR fragments out for the assembly.

Transcriptic's API covers the rest of the devices: https://www.transcriptic.com/platform
Screenleap (YC W12) is hiring sales reps
Screenleap allows people to share their screen so that it can be viewed from any web-enabled device without installing any software. We also allow developers to add screen sharing to their applications using our screen-sharing-as-a-service API. Our mission is to do for screen sharing what Dropbox did for file sharing: make screen sharing a hassle-free experience that just works across all devices.

We have built a product that users love and we need your help to help scale the business. We are looking for an energetic, hard-working individual who is hungry to help take our sales to the next level. As a sales rep, you will directly contribute to the top-of-the-funnel sales effort by identifying and nurturing the best future Screenleap customers and by providing professional pre-sales support, working alongside our CEO. With the right attitude and the right activity, this position is open to a longer-term opportunity with aggressive career growth.

We are seed-funded and on track to be profitable later this year. Our office is located in the heart of the SoMa District of San Francisco close to BART and Muni. As a company, we value simplicity, creative solutions, and the ability to get things done. We offer a competitive salary, significant equity, and a flexible work schedule.

Responsibilities:

* Identify top quality leads through discovery and qualification of our growing user base

* Provide front-line support on the inbound sales email and phone lines, both offering direct assistance and triaging to the sales and support team as necessary

* Source new leads through outbound prospecting and research efforts

* Close short-cycle, transactional business

* Consult clients on Screenleap best practices and trends to provide meaningful recommendations

* Collaborate with the rest of the company to optimize company sales efforts

* Professionally represent the Screenleap brand, vision, and values at all times

* Achieve and exceed designated sales goals

Requirements:

* 0-3 years of experience with interest in sales, marketing, or business-related field

* Previous experience at a startup, software, or tech company

* Comfortable with both inbound and outbound phone calls

* Exceptional writing and communication skills

* Strong work ethic and commitment

* Positive, team-oriented attitude

* Co-op students and recent grads are encouraged to apply

Interested? Please email us at jobs (at) screenleap.com.
Weren't you just saying men are more prone to violence when bullying? What's a less mature way of dealing with your emotions than resorting to physical violence?
> And it's not just tech.

It also applies to countries. Look at the increasing resources that go to people who produce little or nothing of value to others eg lawyers, lobbyists, politicians, financial engineers, LBO operators etc. Not to mention many of the people on welfare.
Ask HN: Should I be using Chrome?
It really seems to be a trend that for anything to work one should use Chrome these days, not? On http://aprilzero.com I was not able to see the rotating animation(s), some things are garbled and the whole site feels more fluid in Chrome. http://growth.tlb.org/ does not work at all, it is just a static picture for me.

I'm still quite content with Firefox but I often find myself checking in Chrome if I'm missing something...
> As far as I'm aware, the only thing it really adds beyond capabilities of a smartphone is the wearable camera

That's basically saying that smartwatches are equally useless. I can't speak for Google Glass but I'm really happy with my smartwatch and there is a lot of utility you can't get from a smartphone.
It has better fonts and whitespace than bazqux (to name one I like), and it's better for reading a lot old comics. Most feed readers seem to be designed for reading today's new postings quickly rather than binge-reading old xkcd.
The background movies that I saw while watching for a while just weren't appealing. AirBnb is full of beautiful, crazy and exciting accommodation options and now instead of showcasing those, they're pushing fairly bland movies and generic location shots first. Any travel website can do that.
I find it a bit strange that he is currently on Koh Tao and his latest run was 5 hrs ago in San Francisco? :)
Living in the Matrix with Bytecode Manipulation
> If your assets are worth less than your liabilities, you're technically insolvent.

No you aren't. It just means you have a negative net worth.

insolvent - unable to pay debts owed.

Think of people instead of companies. I suspect a majority of people in America have a negative net worth. That doesn't make them insolvent. It just means they have lots of college loans and they are working to pay them back.
At the filesystem layer? No, never. However even in the earliest of days file extensions were common. They followed the usual UNIX preference for brevity: ".c", ".h", ".o", and ".a" were all early arrivals. So even though they didn't cram extensions into the filesystem, they weren't allergic to it as a convention.

In the 80s you started seeing things like "resolv.conf" appear, so they didn't stay mostly-single-character for long.
Thanks for the detailed info! Really appreciated :)
>When homeschooling is workable, going to school is often still a better aspect exactly because having a huge amount of experience with both the good and the bad of social settings is incredibly valuable as an adult (and that most adults have such experience is one of the main reasons adult society does tend to be less nasty IMO - people get fed up with it).

No, the most capable students should be homeschooled if you have the opportunity. They'll end up better-adjusted and will be able to learn more material more thoroughly.
To anyone who finds this as infuriating as I do: take consolation in the fact that the Streisand effect will probably ensure this restaurant's bad service will now be known by an even greater public.
Correct. I have done scrutineering in Australian elections. It is fun as you get the local results before anyone else. Also you see the comments people write on the papers

Eg Youse bastards r al liers!
> As software continues to improve

That's a fairly big assumption.
The reason Moore's law worked so well is largely because of this. When we began creating transistors on integrated circuits, the only thing preventing us from making them exactly as small as they are today were things like cost and the capabilities of fabs to make them reliable and stable. So ever since we started making them we've stepped down the size by about half, rather than something smaller that would be more difficult and expensive to make. The entire manufacturing industry gradually became more efficient, increasing reliability and reducing the cost of fabricating the integrated circuits.

The history of performance speedup hasn't been solely due to doubling the transistors. Other types of architectural improvements in memory, buses, parallelism, multiple cores/threads have yielded performance doubling or more. Memory access has always been a huge latency and there are lots of ways to improve that without just making the transistors smaller.

We have a lot of work to do still! The majority of our computing has been on the x86 architecture, which basically stems from the 8080 which was designed in the mid 70s. We can still discover new and better architectures and materials. It's just the standard shrinkage of IC's that was the basis of Moore's Law originally has reached its limits.
Vint Cerf on Colbert
The intersection of HN readers and Colbert viewers is probably pretty large but I still thought this was worth contributing.

Watching Colbert (and Stewart) I notice how much the internet informs their content. So when they invite and engage with one of the internet's principals it's hugely satisfying.

Vint Cert was the guest last night (Tuesday). The icing on the cake is that Vint not only avoids becoming a plaything for Colbert - as many of Colbert's guests are - but that he knocks Colbert off balance. And Colbert, as he always does, handles it with aplomb.

Great watching.

Part 1 of the interview:http://thecolbertreport.cc.com/videos/08a2dg/vint-cerf-pt--1

Part 2 of the interview: http://thecolbertreport.cc.com/videos/x9hnxr/vint-cerf-pt--2
I used to follow with joy of a kid that gets new toys, the release of each new processor and the new set of available opcodes.

Nowadays even C++ is simple, compared to mastering all the opcodes and their side effects in latest generation processors.
i personally find my pebble to be more useful than my glass as well. it's far more reasonable and easy to use on a daily basis.
Kindles are great for books I'll read sequentially, in which I'll never need to consult a specific section, and in which I'll never have to page back-and-forth. So, all fiction and most nonfiction I enjoy having in Kindle format. Textbooks and references I want to own in dead-tree format.
I wonder how they'll apply this plan in France, where the spirit of the law is, you may massively fire people only if it's part of "plan social", and the only argument is ofthen it's-this-or-we-go-bankrupt. Especially:

In those kind of schemes, you must ask who wants to leave, give them a package, avoid those with children, the older ones go last, etc. So I doubt they'd let go of the worst people first.
Hello World Design Goes Green
I want to read the "How to setup Photoshop" article that's in the old version of the page but the link is dead. Where can I find it?
Yes but if someone went to those lengths they could just use a hidden camera. My fear is not some very unlikely determined person secretly recording my conversation, my fear is giving every single person in the world an easy tool that they will use that can also secretly record conversations.

Hidden cameras exist, but there is very little reason to use one in everyday. But giving every single person a thing they have constantly that does this functionality is a real change. The linked article mentions how cameras were banned, but I still dislike cameras and if I see people with one in public taking photos I will avoid them. If those cameras were always out and always pointing at people I would feel very uneasy.
I've always wanted to get into plant breeding. Unfortunately it's a bit late in the year. One crazy idea is to use robots to individually monitor hundreds or thousands of different plants. I actually looked into doing this and it's by no means trivial. Land to experiment with isn't the limiting factor.
This is quite common.

I have had a similar call from one of my bank's partners identified themself as being from my bank. I asked for verification of who was calling and a contact number then called the bank who explained the arrangement and verified the number.
> YC's goal is to help startups take first baby steps and raise money on a larger scale.

I thought YC companies have moved up in maturity over the years. More specifically, I thought current YC batches have more companies that have built product, found early product/market fit and are now ready to grow.

While phrased as a statement, the above is more of a question, since I don't know the answer.

That said, "and raise money on a larger scale" is still probably spot on and hasn't change much over the years.
You can search around CfA's blogs, their Brigade people, the Sunlight Foundation's blogs, Knight Foundation's blogs, Techpresident's blog, mySociety's blogs, Open Knowledge Foundation's blogs but to me the best example of a great library turned into a makerspace is https://www.fflib.org/make/fab-lab.
To which we have no answer

We do have the answer, it's just unfashionable: "Who said life was fair?". There are plenty of things we experience as humans that aren't good, but the tradeoff is generally worth it. Having a job is one example.
Why doesn't everything just stream as with music and video? I hate the "subscribe" concept. I just want to browse around an listen stuff here and ther. Maybe bookmark some favorites.
That's basically what I ended up doing. After I got rid of the books, I imposed a rule on myself that except for rare cases where the book itself is an extraordinary artifact I would only buy books to cut and scan. My previous books were either replaced by ebooks or for the rarer books by buying new or used copies and cutting and scanning them. I was lucky enough that my employer at the time had an industrial-strength paper guillotine and high-volume scanner.

The paper guillotine was impossibly heavy to carry around and terrifying to operate.
As mentioned above, in Preferences -> General, untick "Prompt for test-release updates", then run a check for updates again.
Agree with your comments on Downcast except its Mac version. It's somethings that is unusable for me - high CPU usage, sync problems (iOS version has them too), app freezing, etc.

Hope Overcast will make other clients better. I'm going to migrate to Overcast for the time being.
Because "home-made" has no strict (legal) definition so it's not illegal to lie or to approximate (the topping is home-made).
I'm sorry but the first one was 20 minutes of "the world is not fair. Some people think its fair but it's not" repeated for 20 minutes.

The second one was "You need to observe people's actions and understand why they do things" repeated for 20 minutes.

Those are both very helpful points but I think people would be better served with some advice or techniques.

For example: Discuss your plans with each person one by one before a big meeting so that everyone will be more likely to see it your way in the big meeting.
I'm halfway across the globe so I can't quite put my code where my mouth (well, fingers) is, but this is awesome! I hope you manage to make something great!

If anyone needs any help with writing low-level software for a project here, or with anything requiring electricity, I'd be happy to help if we can release my code/schematics under a reasonable-ish open source license (BSD, GPL, MIT...). I just moved in to a new apartment so I'm kindda busy for the next two months or so, but I should be able to squeeze in at least some time.