skysight-inc/HackerNews huggingface dataset:
So, the other interesting paper which I failed to cite was this one:
http://www.ncbi.nlm.nih.gov/pubmed/24265211
in which we showed that rosetta needed to include bond angle terms to accurately model some proteins.

That said, I'm a bit surprised you found what you did about AMBER (and other force fields), or rather, that you didn't publish. The cornell et al force field was later acknowledged to have serious problems with protein folding, but a number of improvements have been made since then.

Anyway, I would have happily published that result with you (I worked with Kollman, have worked with Baker and Pande, and desperately want to see the force fields improve using machine learning). There was a guy at BMS who was working on this back in the day ('99-2000) who was using ML and the AMBER folks trashed him because they believed the force field's transferrability from small molecules to proteins was valid (in many ways it was, but it got some key details wrong).

Ifd you think there is a straightforward machine learning for force field problem that can dramatically improve ab initio folding with distbelief and exacycle, let me know. It shouldn't be hard to figure out my email address if you look at the papers I cited and do some basic set operations :-)
HAProxy 1.5.0 released
Yes! This would have been a much better way to go.
F9R 1000m Fin Flight | Onboard Cam and Wide Shot
but I would be interested to know if that is a mainstream view.

Quinn's unique opinions are never the mainstream view. He's an energetic and smart advocate for anything, no matter how extreme, that would make the patent bar more money at the expense of actual innovation.

You can read his blog for a series of crazy overhyped claims for big new ideas in software whenever patents are issued. They're always bad or old or trivial or obvious ideas that some big company has just managed to get a right to monopolize. Canceling all the patents he loves so much would be very, very good for the industry.

As to whether this will affect many patents in the long run, we can only watch what the CAFC does in the next year or two.
Yep, that's what I suspect as well.
MATLAB will recognize if you've got FFTW or ATLAS or other highly tuned numerical libraries installed. And MATLAB will then use them whenever possible.

If Intel does a good enough job of providing a collection of compute kernels and the surrounding CPU libraries to make using them roughly as "easy" as CUDA then a lot of people will pick that up.

I don't have any hard numbers but I would suspect that there are a great many more people who use MATLAB on a CPU than those who do MATLAB->HDL. So what I'm speculating about is that Intel might support those folks who use MATLAB on a CPU for more general purpose things.

Does that make more sense?
"The Internet Has A SuperPAC" says Steve Wozniak, endorsing Lessig's Mayday.US
I don't disagree with you, but isn't it reasonable to think that browsers now can play most videos without any issues?
Please don't. There used to be thousands of these on blogger, it was awful because they'd often show up in google results.
To use the Ikea trademark when referring to Ikea brand products doesn't dilute the mark.
It's incumbent on IKEA to police unauthorized use of their trademark somehow, but that doesn't have to mean that they must start by sending a nasty letter. When Jack Daniels thought their trademark was being infringed, they started by sending a nice letter simply asking the infringer to stop.

http://abovethelaw.com/2012/07/cease-and-desist-letter-of-th...

Another way to deal with unauthorized use of a trademark is to authorize it. So IKEA could have started with a letter asking IKEA Hackers suggesting a potential agreement and a nominal fee. An imperative cease and desist letter isn't required.
I don't disagree, and I suggested as much to the Xilinx folks (well their EVP of marketing at the time) that if they just added $0.25 to the price per chip they could fund the entire tools effort with that 'tax' and since they would be 'giving away' the tools they could re-task all of the compliance guys who were insuring that licenses worked or didn't work into building useful features.

Their counter is of course that they have customers who sweat the $0.25 difference in price. (which I understand but $10,000 in tools and $15,000 in consulting a year is a hundred thousand chips. Which they say "oh at that volume we would wave the tooling cost." And that got me back to your point of "You already have their design win, why give them free tools? Why not give free tools who have yet to commit to your architecture?"

It is a very frustrating conversation to have.
Yes, in ancient history, video codecs sucked, browsers sucked, and the only way to play video was through plugins that sucked.

Now, all the browsers are pretty good at dealing with video, the codecs are hugely improved (although, there's some headaches with IP) and the plugin is dead.

Nobody ever actually wanted gifs. They want short, small videos that are guaranteed to work in their browser and that they can be pretty sure aren't going to have sound. We can now deliver that.
Sustained bandwidth is not out of the ordinary. I consistently get the same bandwidth day after day, but I realize at times it could have issues, because I don't have a dedicated line.

When I don't use QoS, I can't download a large file and skype at the same time. If I use QoS on my network, it's no problem. Clearly this means my ISP is not doing anything particularly special with my data, and I get on just fine.

I go through Midcontinent Communications, one of the better ISPs in the US.
I actually CC'd the CEO on my reply, wherein I basically implied that the previous email was misleading and that I was expecting a less formal mode of communication. But like someone else said, I don't think the CEO actually sent that first email. I suspect the recruiter sent it on his behalf.
Funny, the link for "using Elasticsearch" points to an interview I gave ;)
He raises some good points on ES current problems with master election, I have raised it with the ES team during meetup with them and we have a work around the issue (we discovered the bug during our testing). Its important to know the soft points of the system your using and how to work around it. We feel like we have a good workaround and I think that has been the point of his series is to point out the flaws in common tools and you should be read to work around them. But he found a single flaw and attacked it hard, so, I am not sure throwing away the whole thing for a single flaw is a great recommendation.
In case anyone is still watching this thread--my version:

http://blog.foundationdb.com/minimal-explanation-of-the-cap-...
CDC: 75 US government employees may have been exposed to live anthrax
You are the GM of a team. You play against 31 other players in a professional league. You sign free agents, draft players, deal with injuries, choose plays for your team to run, when you want. Every real day, is a game "week" so you play a game a day, unless it's the offseason.

You have a salary cap you have to deal with. Trade with other human players. Try to win the Championship.

A season lasts a real time month from start to finish. The players are all fake, they grow up. They make pro bowls, and try to make the hall of fame.

We have leagues that have run over 70 seasons at this point.
I'm curious what industry you're in. My impression is that most engineering teams wouldn't have a problem with the irreverence, but that teams in some industries (banking? health care? defense?) have more of a need to look like Serious Grown Ups.
Chrome on OSX 10.9 works just fine. I'm looking at the example video now.
It was important for us to focus on the MVP but we've actually discussed both of those options from day one.

There are some disadvantages to self hosting a monitoring tool. But certainly there are circumstances where self hosting is very important.

I could certainly see us releasing code for the website and monitor daemon under an OSS license at some point.

Thanks for giving it a look!
The gifs are annoying when one is trying to focus on the text and sees movement out of their peripheral vision.
I don't know if this applies to other classifying algorithms, but I guess this will mean better CAPTCHAs?
I saw it too. The odd thing is that 4chan's equivalent doesn't show any such loading indicator. Also, looping a video in HTML5 doesn't require Javascript.
As someone who operates a free service, this is a very unintrusive way to get some extra revenue and I wouldn't complain about it if you want to see these kinds of sites stick around :)
Also, I wonder what everyone thinks of the LOGI boards:

http://valentfx.com/
Because the person who runs the site in all probability is a male if you don't know otherwise. It's a non-sexist probability assessment.
I'm guessing something more like Football Manager than a game where you're moving the actual players in real time.
How Much Is Winning the NBA Draft Lottery Really Worth?
thats correct, BillForward offers a deeper subscription stack making it easier and faster to start billing and handling upgrades, downgrades, switch plans etc....
Agreed. I got an offer from a YC company about a year ago. The offer was lower than I currently make by a large margin. I tried to negotiate, and the CEO came back in a huff and basically said I was an idiot for turning down the job, and why do I even bother with startups in the first place if I want so much money? Well, that's the thing, dude. I don't need your job. You need me. You got the whole thing backwards.

Anyway, yeah, I agree with you completely.

(And by the way, keep pushing on the unit test thing. It's something worth arguing for. Or next time, build in unit tests into the project estimate instead of setting it aside as a separate project. Good luck.)
Videogrep: Automatic Supercuts with Python
I saw it everytime the video looped. Left a distinct impression with me that the real GIF version is better.
"precursor of html"

please elaborate.

HTML is based on XML, a language with two primitives, strings and children. Why would you ever use that as an interface if you want something to ever be performant?

What we need is a retain-mode scene graph, where some of the nodes on the scene graph can be HTML documents (with URIs).

Developers don't want a one-to-one relationship between the window object and documents. They instead want a one-to-many relationship. The <article> tag is proof of this.

Take Twitter for example. What is each tweet, but a 140-character document? The application for displaying an infinite list of tweets is not a document, but a multi-document viewer. The Facebook feed is the same thing.

If anything, this would prevent the shenanigans of blocking viewport resizing, because the user could choose an HTML document node on the scene graph and decide to make it full screen (the same way twitter allows you to click on a time stamp to get a permalink)

This retain-mode scene graph would need to support URIs so that you could always link to a subgraph of the scene graph and only view that part.
Wordpress is a pain to develop for and plugins are a minefield, it's content delivering method doesn't scale. The only reason a lot of people are using it is because it is easy and cheap to get it up and running.
Public Schools Are Hurting More in the Recovery Than in the Recession
Thank you! I was gonna post the exact same thing. Nice website, though.

I encoded the gif in 420 (subsampling), 422 and 444, having a nice quality with 444 with VLC, I embed the three different videos in a web page and when playing in my browser, they are all as bad as the twitter video! I thought that Firefox was using a standard library to play MP4?
HTML & CSS were developed to abstract documents and present them through a web browser.

You'd be better served making a native app that integrates with a RESTful web api on the backend.

You still get the reach that the web provides, while having access to all the presentation and graphics goodies you get in a native app environment.
Presumably a dupe of https://news.ycombinator.com/item?id=7916160.
drewda's comment below[1] is an example of a JS library that implements Cassowary in the browser. It's called Grid Style Sheets.

1:https://news.ycombinator.com/item?id=7917646
Ha. I've had recruiters try to set me up with companies that I've already interviewed with, and once I had a recruiter try and set me up with a company I'd already received an offer from (but declined for various reasons). It's not really their fault, though. They can't know the details of my personal network and history. Still, it makes for funny stories...
> The CAFC will eventually overturn this case

Why would the CAFC, even assuming it could, want to overturn a case in which the Supreme Court affirmed both the judgment and the dominant reasoning of the CAFC? I mean, that would go beyond not caring what the Supreme Court does into active spite.

> The idea of a single subject court was a novel experiment in 1982

The CAFC isn't a single subject court, and both of its two immediate predecessors (the United States Court of Claims and the United States Court of Customs and Patent Appeals, 1929-1982) were more like single-subject courts than the CAFC is, so, insofar as the CAFC could even remotely be considered by such a court, it wasn't a "novel experiment" in that direction (and Court of Customs and Patent Appeals prior incarnation as the Court of Customs Appeals, 1909-1929, was a single subject court, and until 1914 was a single-subject court with no further avenue of appeal.)

The CAFC was part of an evolution away from narrow-subject courts, not a "novel expirement" to try a "single subject court".
Seven things billion-dollar startups do.
With OpenNIC you can do that: http://www.opennicproject.org/
Thanks for the tip, I'll look into this more.
Had the same issue, you have to be logged in...
I m currently trying to integrate stripe subscription api, for my soon to be launched service. Could you tell me why I should consider you instead of them?
You can try it yourself, it's free: http://www.tobiasgame.co.uk/
Performance of quantum computer no better than ordinary PC, say analysts
Hi, thanks for the feedback on messaging.

What we are trying to do is enable companies to have a single billing platform that grows with them from simple flat priced subscriptions all the way up to subscriptions which have multiple components and pricing strategies.

For example some of our customers sell their subscriptions with 3 or 4 components, for example international calls, local calls, 4g usage, 3g usage etc. Inside each of these units they give discounts the more you use. For example up to 100 minutes of X is $1 a minute, whereas anything above 100 minutes X is charged at 75c a minute.
I've worked with OpenWRT in the past (it's running at my parents' home, and I've done some embedded development), but frankly I'd like to reduce the amount of devices around me. If I can make my seldom-used linux pc my NAS and my Access Point, I'm fine. Transmit power shouldn't be a problem where I live, it's just the software hassle that's keeping me from doing it.
Balling! I'm actually going to Canada today so I will give it a test drive.
To be fair: they don't want short, small videos any more than they specifically wanted gifs.

They want moving images that load quickly. Which has meant short/small/gifs, because most US bandwidth still sucks. And thanks to the mobile explosion it now means short/small/h264.

But I bet that as people become used to 5-10x space savings from h264, they'll quickly respond with videos having 5-10x more data. (larger/longer/higher-res clips)
Thanks, mcintyre1994! We're using Susy and Compass for responsive CSS. We have plans for an Android version, as soon as jpn learns Java. :)

Great feedback on our home page -- you're right about the iOS emphasis, and limited content feel. We're currently refreshing our home page, and will be sure to work these issues out. Thanks!!
We (speakerblast) created a wake lock solution that works in iOS6 & iOS7, as our web app syncs audio across devices.

In iOS8 as of now audio playback in Safari stops when the devices sleeps and or when the user exits Safari. This is not how it was previously, rather audio played in the background and audio playback kept the device in a semi wake stage.

Were hoping this is a bug they'll fix before the final and not the new way forward.
Seriously: they are just trying to make money. If Verizon is so bad then why are they the biggest carrier? It is because they have the best network. I don't want to pay Verizon 10% of my take home pay, but I also want to have a signal on my phone in Inlet, NY. I welcome some good competition, but until then the options are limited if you want the best coverage.

BTW: I am a happy Republic Wireless customer right now.
I can't tell what's an ad and what is content on that site.
Note that currying is not necessary for partial application, here is partial application implemented in C++14: http://coliru.stacked-crooked.com/a/bed4a4fdd6e856b0

However, I find lambdas with the extra parameters repeated more readable than partial application.
And there are also tons of reasons for the responsive solution. It all depends on your requirements and use cases. I don't think there's way to unconditionally say that one is better than the other at the moment.
I create a struct representing each thread. Outside of a debug build, these structs are empty. This is always passed as the first argument to any interesting function (as it happens, while the C standard doesn't guarantee it, in GCC this generates the same bytecode as omitting the parameter), and always named th.

When defining any global variable designed to be accessed without a lock, I also create a LOCAL_varname_ASSERT_THREAD function that takes the relevant thread as an argument and does nothing, for static assertion of type equality. This is all wrapped in macros to be convenient and readable.

When you really start using your type system, it's amazing what can be "a type error", even in something as kludgy as C.

At this point, I've been working on the codebase for a year and a half, and it's been in production for much of that. It's >100k LOC, has multiple threads, generates responses in <10us, has been through some major refactorings, and I've had maybe 3 problems involving concurrency that even hit my tests, with one (a high level livelock in my message passing) winding up in production. I don't know how I would have managed this without access to these kinds of static guarantees (which is not to say there aren't any other tools which could have replaced this one, but it is to say there is tremendous value to this tool when you know how to use it!).
Edit: just FF'd to the 3d cube bit.. nm. We can't do that without WebGL. That's what I get for not watching the entire video.

Not sure what your getting at. The Wayland demo looks like it could be completely recreated with existing CSS3 3D transformations.

Here's a similar example in a browser using HTML and CSS3. These transforms can be used on anything you can fit in a DOM element: https://www.webkit.org/blog-files/3d-transforms/morphing-cub...
Django PR: Replace primary/replica terminology with primary/secondary
In the original post, he said that they allowed him to use the "IKEA" name as long as he removed ads from the site. Considering the ugly banners down the side of this page -- which are for competitors of IKEA -- this seems pretty reasonable.
Hey, we provide a hosted out of the box subscription checkout for users who do not want to build. We also support you building your own checkout via our API
> HTML is based on XML

No, its not.

HTML is based on SGML (it was originally an SGML application profile, though as of HTML5 it is no longer.)

XML was invented after HMTL, was inspired by HTML, and is also an SGML application profile.

So, insofar as XML and HTML are related all, its closer to the reverse of the relationship you describe.
I see. Than I still don't understand what you\ your employers benefit from paying in Bitcoin ?

Unless your USD-->Bitcoin (and the other way round) transaction costs are lower than the average joe's, why would I prefer being paid that why ?
Even if you cover the transaction costs I'd still prefer to be paid in USD and that you'd pay me the additional transaction costs instead of converting USD to bitcoin on my behalf.

Unless it's a finance backdoor in terms of tax, etc, I can't see the reason in doing it.
Django PR: Replace README terminology with GETTINGSTARTED
We faced this problem at my last startup, and I think we handled it reasonably well.

The team remained 3 founders until Mar 2012 (1 year after launch) when customer support and other operational tasks started significantly distracting us from more critical things like building product and growing the userbase. At that point we hired a community manager to handle support / ops. We were profitable by then.

There were a few major advantages in delaying this long:

- Doing support ourselves helped us achieve product-market fit. It's critical to be in contact with as many users as possible in the early days.

- Saved money. Early on, a community manager would have had 2 hours of real work per day, and would have cost us $50K / year. Didn't make sense unless there were 6+ hours of work to do per day.

- Kept us from building support tools. Since we were all technical, we just ran everything from the command line. And when we hired our first community manager, we hired someone with immense coding aptitude. They handled support from the command line for nearly a year when we finally built out enough tools for a nontechnical person to do the job.
Mozilla unveils its plan to fix online comments with the help of some big names
Would be nice to have some tweens/effects for movement & resolve phases.
Completely agree. Those thinking of delegating/outsourcing customer support should read Fred Reichheld's book on Net Promoter System and I'm sure they will change their mind.
Not exactly. If you browse down that thread and read the dissertation and the accompanying slides, you see that that demo goes well beyond positioning a rectangle (texture) in 3D space (which we already do at famo.us).

That guy went on to explore cuboids in addition to rectangles as a basic windowing primitive.
Oh yes. It's all a huge conspiracy. Can't let the sheep get too uppity.

Baaaa. Baaaaaaa.

After all that's what open source is for, right?
I am very, very jealous of you. I've got a coworker who used to live in that part of the states who tells me leaving that particular ISP was one of the hardest parts of moving here :)

That said, I bet they got out in front of projected growth so they have a large surplus of capacity. Still, I'd be willing to bet you large and ridiculous amounts of cash that the right combination of growth + popular event would result in contention.
Disaster recovery is easy to put off forever because you don't need it until you do. When it happens it can also kill off your company.

I've been involved in companies that went 14 years without a disaster. Another company I was involved with had 2 in a span of 2 months, each taking between 2 and 3 days to recover from.

Regardless of whether I need it or not, I sleep better at night knowing a decent plan is in place. Which means I can perform better during the day.
Samsung’s new Smart Bike features lane-marking laser pointers
There is a sandbox you can try.
Great! Happy travels!
Good thing browsers run JS, eh?
Yes, this was all inspired by Nick Winter's epic 120-hour workweek, which he posted a time-lapse video of. Here's a direct link to his video: https://www.youtube.com/watch?v=E0qlr22cF14

And while I'm at it, direct link to Bethany's: https://www.youtube.com/watch?v=ODhx-CbX9lg#t=40
Whiteboard: upvote on ProductHunt
Just announced Whiteboard and we are featured on ProductHunt today. Would love to hear your feedback and thoughts on our product

Some upvote love on ProductHunt would be appreciated!
The Wolf Among Us Song: Avengeline – Fear
Finally, Elastic Computing That You Don’t Have To Share