My interest in the topic is mere curiosity. So far, while it doesn't prove anything, the skeptical side of the argument is mostly nonsense. While yours isn't an exception I do have to say I've never seen a skeptic raise such elegant issues. For completely uninformed conjecture yours is most admirable. It reads as if you know what you are talking about (at least the medical part)

(I cant think of a nice way to say "conjecture", sorry about that.)

The link is there because physicists claim an optical microscope is limited to Rayleigh criterion.[0] Their uninformed conjecture holds that Rife's microscope[1] is not possible. After imagining the microscope not to exist it of course follows "logically" that Rife could not adjust the frequencies to those variations in shape and ph that you so elegantly pointed out.

But try telling that to the medical professionals looking though the microscope? A bit like going to the airport to tell people heavier than air flying machines are impossible. According to the physicists the further Rife zoomed in the less credible he gets. Maybe I'm ignorant about the terrifying consequences of accepting empirical observations physics?[2]

In short:

in 1931 Dr. Arthur I. Kendall, Director of Medical Research at Northwestern University and Dr. Milbank Johnson of Pasadena Hospital. Dr. Alvin G. Frood, President of the American Association of Pathologists joined Rife's research. Moving microorganisms from prepared, diseased human tissue were photographed and filmed. On November 20, forty-four doctors attended a dinner to celebrate "The End To All Diseases" at the Pasadena estate of Dr. Johnson[2]

in 1932, Kendall speaks before the Assoc. of American Physicians at Johns Hopkins University about the successes with Rife's methods and treatments.

In 1933, Richard Edwin Shope discovered the first mammalian tumor virus.

Also in 1933, Rife completes the universal microscope. Upgrading his resolution claims from 17 000 X to a resolution of 31,000 times and a magnification of 60,000 times.

In 1934, The first clinic is opened. A special University of Southern California Medical Research Committee chaired by Milbank Johnson is formed to oversee the research. Committee members are: Whalen Morrison, Chief Surgeon of the Santa Fe Railway. George C. Dock, M.D. George C. Fischer, M.D., Children's Hospital of New York, Arthur I. Kendall, Dr. Zite, M.D., professor of pathology of Chicago University. Rufus B. Von Klein Schmidt, President of USC. Also in attendance: Dr. James Couche of San Diego. Dr. Carl Meyer, Ph.D. of the Hooper Foundation, SF. Dr. Kopps of the Metabolic Clinic in La Jolla. The clinic is held at the Scripps Institute in La Jolla. Sixteen terminally ill people are treated. Fourteen are cured in three months, the other two are cured in six months.

In 1935, Dr. Milbank Johnson opens a second clinic with the same results.

In 1937, Dr. Milbank Johnson opens the third clinic with the same results. Drs. Couche of San Diego, Gruner of Montreal are also having great success.

In 1938, Fourteen machines are built. Two go to England, one goes to Dr. Richard Hamer of the Paradise Valley Sanitarium, one to Dr. Arthur Yale, two to Arizona doctors, and eight to Southern California doctors. Dr. Hammer cures an 82-year-old from Chicago of terminal cancer. Through this man, Morris Fishbein, head of the AMA in Chicago learns of Rife and his work. Fishbein visits Rife. Wants to buy in. Rife and his associates turn him down.

In 1938, The AMA indicts Rife for fraudulent medical practices. Rife wins the case, the AMA is made to pay $200,000. During the trial and afterwards the AMA visits all doctors involved with Rife. Those who didn't stop using the Frequency Instruments lost their medical license.

Rife makes a career switch to alcoholism.

the end!

I know it sounds very dubious, I would stick with the radium therapy.[3][4]

You could try a web search for more information and/or check out http://www.rife.de

Good luck,

[0] - http://physics.stackexchange.com/questions/38146/optical-mic...

[1] - http://query.nytimes.com/gst/abstract.html?res=9C02E0D81131E...

[2] - http://www.dailymail.co.uk/sciencetech/article-1361863/Most-...

[3] - http://1.bp.blogspot.com/-sN85jvTBETs/TVkdsnt-HWI/AAAAAAAAAq...

[4] - http://www.marketing-professionnel.fr/wp-content/uploads/201...

[5] - http://upload.wikimedia.org/wikipedia/en/0/01/Radium_therapy...