skysight-inc/HackerNews huggingface dataset:
IANA*, but as I understand it there are fundamentally two forms of antibiotic - variations on penicillin, and variations on vancomycin. While varying the exact form of antibiotic works to a point, eventually you run into the problem that bugs become resistant to the basic underlying common mechanism within the family of antibiotics. Everyone accepts this process with penicillin-ish drugs, but when it starts happening to the vancomycin-ish drugs, that's when it gets scary, because there is no 3rd tier.
Here is a link to the World Health Organization media release[1] about the new WHO report, which links to a fact sheet summary[2] of the findings, and to the full report.[3] What's new here is the comparative data from different countries. It has been known for a while that multidrug-resistant tuberculosis is a grave problem in India,[4] for example, but the new report makes clear that antibiotic-resistant microorganisms that cause major human disease are present all over the world.

Some of the other comments posted here ask, well, what can we do about this? A submission to Hacker News from 189 days ago linked to a PBS report about the views of a Centers for Disease Control and Prevention epidemiologist in the United States[5] who advocated specific policy changes, some of which have been adopted since then. The discussion of that submission (including one of my highest-karma-ever comments[6]) provides more perspective on some biological evolution issues that are being brought up again in today's discussion here.

[1] http://www.who.int/mediacentre/news/releases/2014/amr-report...

[2] http://www.who.int/mediacentre/factsheets/fs194/en/

[3] http://www.who.int/drugresistance/documents/surveillancerepo...

[4] http://online.wsj.com/news/articles/SB1000142405270230344420...

http://articles.economictimes.indiatimes.com/2013-06-23/news...

http://www.iom.edu/Reports/2012/Facing-the-Reality-of-Drug-R...

http://www.tbcindia.nic.in/pdfs/RNTCP%20Response%20DR%20TB%2...

[5] https://news.ycombinator.com/item?id=6599040

[6] https://news.ycombinator.com/item?id=6599795
The Self-Driving Car
> other people can see it and flag if you make inaccurate claims

Hah ha ha...
When I see resume inflating on LI, you think I'm going to annoy someone I already have a relationship with by flagging it so recruiters can get accurate information?
There's also more information at http://ordered-universe.com/ - the original site for the project.
I wonder if it's like when I take a look at software and all anyone else can see is the output, but I can appreciate the underlying mechanisms and even be awe struck. And my colleagues are wondering if we're looking at the same thing.
That's quoted out of context - you left off the next sentence:

"Obviously we’d prefer that you use us, but the main thing is to make sure that you get them in a place where the data belongs to you and not someone who wants to keep it under lockdown."

Sure there's a marketing message there but it's buried at the bottom of a long quite involved post, and fully disclosed. Hardly discredits the article just because he's an interested party, IMO.
I don't know any evidence, that teaching the "mechanistics" of math should lower the chance of understanding it.

Quite often "root learning versus understanding" is the difference between being able to show and demonstrate you know your stuff ("root learning") and not being able to show or demonstrate it, but you think you kinda know it ("understanding").
Yes - but drawn by the physics department at the best university in Europe for astronomy.
JS engines are getting smarter about this, but you can't really rely on it. I suggest naming your functions if don't want them to be anonymous.
If this[1] research leads anywhere, we may not need totally new drugs. Only modify the existing with polymers.

[1]http://www.sciencedaily.com/releases/2014/04/140414154454.ht...
Film download prices 'to be determined by screen size'
http://www.media.net/publishers

media.net, my previous company. We used to consider ourself in competition with adsense. They have some big name customers like forbes, cosmopolitan etc.
1. 26 is not old. Many people are just now graduating at your age. You have some advantage from prior business experience as well.

2. It depends. Can you learn to program without getting a degree in C.S.? I took three classes and programmed for about 500 hours before I was hire-able, let alone useful. Are you willing/able to climb that steep slope?

3. I would suggest that you start out by working on learning to program, either at your current job or in your free time. Do this for -at least- 2 months/100 hours before making any life-altering decisions.

After all that...if you still want to go through with it, it's very, very difficult to learn an advanced subject exclusively in your free time after working 40 hours/week. There's good odds you'll need to either take a long chunk of time for dedicated study or get a degree.
I think you're referring to "the G string problem".

The deflection of the third string at the first fret G# pulls the string a bit sharp relative to the open G on the third string.

There is a specialized guitar nut called the Earvana that has additional material to shorten the open G string a wee bit to compensate for this.

In real life, getting any (non-keyboard) instrument to actually play in tune is the hardest part.
Is there a reason it doesn't show author names when I submit a URL like http://www.sciencemag.org/content/210/4472/903.short ?
There aren't, the name of a function is optional (if you assign it to a variable.) So you can write:

function a() {}
// or
var a = function() {}
// or
var a = function a() {}
// or
obj.prototype.a = function() {}
// or
obj.prototype.a = function a() {}

There is little difference in the function declaration. The difference is if you named it or not.

The reason you have to be careful with the var a = function() {} forms is because variables are hoisted. So while the function will exist, your variable will not point to that function until the assignment happens.
Just lift the USA immigration restrictions to Chinese, and the 'GPD' and middle classes will be yours in no time.
Pressure your government (where ever you may be) to make responsible use of antibiotics a priority.

The misuse that terrifies me the most are antibiotics used on livestock. Particularly the antibiotics that are also used on humans. In my opinion antibiotics should not be used as a growth promoter and only used to help sick animals.
I get what your're saying (I think) but vaccine != antibiotic. We're not (that I've heard) seeing the emergence of vaccine-resistant polio for example.
Twitter will never be mainstream?
Lijit was the best alternative for me, and I went through a good 5-6 networks. However, their CPM's were significantly less than adsense. Their support is really good though and they do actually have control over their inventory unlike a lot of other ad networks I worked with (many networks claim to be able to block audible/video/popup malicious ads but still allow many to slip through). Technorati is decent I believe (only used them for about a month) but their ads must be served out of an iframe (so they can't be contextual - so less CPM) because their ad servers are so slow and they are page blocking.
Don't worry about it. Programming is easier for an adult to pick up than, say, music or math.

Definitely don't waste your time chasing the latest and greatest. Most frameworks are fads — that's why they go in and out of fashion so quickly. Once you solidly understand the basics, and once you have gained some experience (you probably need a year or so), you'll know enough to evaluate libraries and frameworks efficiently.

Build something using the tools you already know. Don't use too many libraries. Don't copy in code from StackOverflow which you don't understand. Don't listen to know-it-alls who respond to your questions with "why would you ever want to do that?" Just code up a solution to your current problem, and move on. You'll be a good hacker before you know it.

PS: I do suggest you learn to program outside the web domain. The web is unusually beginner-unfriendly because (1) you have to keep dealing with the browser-server stateless request-response fundamental design, and (2) the browser and the DOM are pretty confusing concepts.
Well apparmor is like the baby cousin to selinux, or the big brother to the traditional unix DAC. Selinux is more robust but also more complex. Grsec is an attempt at both a MAC and various exploit-prevention techniques. In that sense, grsec will be more effective at preventing "traditional" exploit techniques.

But modern software development is so bad, even after using high-level languages and abstractions, much of the webapp and backend development is rife with security holes. You don't need to use things like buffer overflows anymore to simply extract data or take over accounts. Servers are so easily accessible and botnets are so widespread that owning a server isn't really the point anymore; once you have all their data, who needs root?
Tesla to break ground in 2 states at same time for Gigafactory
Making ad-hoc polymorphism less ad hoc
Yes, excessive use in not only humans, but in livestock.
> They do some really dumb UI stuff around privacy that is trivially worked around using Incognito.

I didn't realize I could work-around the privacy concerns of publishing personal details on a social network by doing it in Incognito mode. Fascinating.
I Quit Email For A Week And Maybe You Should Too
16 cents is a lot. It's 1/6th of a semitone.
Actually, I submitted because I liked how it was summarized and linked to the new york story. Original sources don't seem to be valued by folks up voting.

[edit] can moderators change the submitter to the person who originally submitted this article?
I'm pretty sure that in the background they use some kind of data mining to learn you're identity, and they're pretty good at it since they have all this data.
Whoa: http://futureinterface.tumblr.com/post/75732307855/memory-of...

Apparently this is a independent, minimalist atmospheric sci-fi game currently in development.
Most antibiotics are not created but discovered. They are often species of fungus or other microorganisms that happen to attack certain kinds of bacteria. Take any place on earth where you might find microorganisms, grow them in a culture and then test their effects until you find one with the desired properties (kills bacteria but not human cells) and then you might be able to develop a new drug from it. The problem is we're running out of places to scoop up microorganisms from and the newest drugs are being made from fungi found deep in the most inaccessible caves underground for which bacteria above ground has not developed a resistance to. It's an evolutionary arms race which we're ultimately destined to lose which is why we need to find better ways of killing bacteria.
The OP's comment said "you should avoid being vegetarian" so your comment applies to his as well.

Also, isn't corn healthy unless you process and concentrate the sugars or powder it? I doubt one can gain weight by eating lots of raw or cooked corn unless you slather it in butter or something.
>Just life the USA immigration restrictions

I suppose the Republicans, being pro-life, will support it.

http://en.m.wikipedia.org/wiki/Muphry's_law
Interestingly, the article suggests by size they are literally referring to physical screen size rather than resolution. Surely this would going to lead to people spoofing retina screen phones to watch on their monitors/tv's.
From what I understand, it isn't usually used as a growth enhancer (I may be wrong) but used because of the way livestock is maintained. When you have cows being kept standing in one place to maintain lean meat, they develop infections more so than being able to walk somewhere other than their own feces. So to keep production up and infections down, the livestock gets pumped full of antibiotics.
What's most striking to me is how the older films got the future wrong. Mechanical and computer interfaces of their time were gray and clunky, so they imagined future interfaces would be even more alienating (as things got more "high-tech"). Now the "future interfaces" in our movies have sleeker, more beautiful displays.
Pretty cool! Note: if you're looking for something similar for ruby, we use the java libraries from jruby. It is seamless and we haven't had any issues (besides bugs from Impala itself).
Haha. Don't worry about it. I was just pointing out why someone might not have submitted the original.

(One of these days I might be able to trade in my karma points for the really big stuffed animal, but for now, it's just mustache combs...)
It's worth noting the offers are from companies in the same city. Anyways, I agree. The prospect of opportunity and ownership has always kept me attached this company, but it seems like they have been using it to bait me to the company.
Didn't 2 other companies just raise millions to do this?
The marquee video lags.

I do feel like the landing page adequately communicates what the product is.

Overall, interesting product that I'd like to check out!
One possible concern is that the article uses affiliate links for every recommendation.
How BIG Is Google?
Parallax Pager: Adding Depth To A 2-D Android Screen
Right, I get that, but this article mentions vaccinations as part of preventive care.
You're giving VCs and institutional investors way too much credit. The amount of educated people who buy things based largely on the fact they are popular and growing is still pretty large, especially in a frothy environment like this one. They're more interested in getting out when it looks like growth is over than fighting the legal system to ensure a business can stay in operation.
Introducing FbStart
As the complexity/variability of a product's functionality grows, a product team's ability to ensure quality across all functionality diminishes.

As a consumer of many kinds of things, I almost always gravitate toward the offering that is most simple/focused in its purpose.
This isn't always true, you can buy packs of small porkchops that work out to be about 1.25 per chop.

While this book is interesting it seems to go to great lengths to create new dishes when many compatible traditional dishes exist. For example you can make Schnitzel, Spaetzle, Blaukraut and Brussel sprouts for 5 for around $10.
Cook photobook about Florence, Italy
You're absolutely correct, but I'll answer your question:

> Why hire such an person if there's a good chance he'll do some damage to your company while you attempt to deprogram him, during which he'll be much less productive that someone from a less damaged company.

Hire such a person if you happen to be hiring for a dysfunctional company. They've got the experience, and they'll appear productive immediately.

So then the "black mark" on the resume only becomes a hindrance if after, say, 10 years a person finally decides to break out. It's still possible, but it will take a lot more work.
Duplicate of https://news.ycombinator.com/item?id=7500426.
I completely agree with you. Maybe this was a subtle way to get the public to understand the catastrophe that is global warming as well...
I gave it a shot for a month. So far there was nothing that could convince me that goes beyond a fancy look & feel. Feature-wise it's ages behind WordPress (not suprisingly, WordPress is a huge eco system).

It's missing several fundamental features that make it unusable (in my opinion) for any serious user, such as user management.
Setting up Whatsapp on your Computer
This is a simplified process of setting up whatsapp on your Desktop
"So China, which had been forecast to overtake America in 2019 by the IMF, will be crowned the world's pre-eminent country by the end of this year according to The Economist’s calculations. The American Century ends, and the Pacific Century begins."

You can expect the Economist to tilt this way, but it feels a little over-eager and glib to me (even considering the source). Yes, by one important economic metric, China wins. So therefore, China is "crowned the world's pre-eminent country". (Who makes these crowns, anyway? Wait, let me guess -- they're made in China, but awarded by a London-based committee.)

We've done this one before. Hitchens (http://articles.chicagotribune.com/1990-06-17/entertainment/...) used to call it "Our Greece to their Rome" -- the wise British counselors would advise the Americans how to run their Empire. It's like the committee decided to trade in for someone else to advise.

And "the Pacific Century begins". What does this even mean? Is it just to goad page views and comments? "Crowning the Dragon"? Really? Why so eager to reach for that metaphor? Do we have to search around for something to put a crown on?
Hi Rob, thanks for your expansion on it :-). I see Deis does that in a similar fashion. I'll update the article with this approach, because it's clearly the best way to solve the "host IP issue".
As an SF resident, I'd support something that allowed short-term rentals only if the host is present and the host is the owner. Permanent AirBnB units don't help the housing market in the city.

I find it funny that AirBnB's justification is that their users rely on the money to make ends meet. But at the same time, if you're taking a unit off the legit long-term rental market to put it on the permanent short-term AirBnB market you are by definition driving up rents for everyone in the city by reducing the supply of rentals. So the justification is: "San Francisco is so expensive, our customers need the ability to drive up rents even more because rents are so high!"
I know I am not going to change your modus operandi, but I must publicly point out that I fully, absolutely, disagree with how you execute your hiring. If you were working for me, you'd soon be working for someone else.

Your approach is a minimal-effort Pareto principle based hiring. By eschewing any and all candidate information sources other than the market leader professional social network, you get access to a pool of 80% of the candidates with minimal effort. For you, it's great. For your company, it's passable. For the candidates, it's disgusting.

I know many professionals, top of their class, that do not maintain their LinkedIn profile. Some don't even have one (usually out of principle). You absentmindedly dismiss these 95th percentile professionals in the "junior, shady or clueless" category. It reeks of profiling, smells like laziness and must be called out as bad practice.
If we were a rational species, we would recognize we're at war with another species that's killing millions of us, and spend a portion of our military budget on antibiotics research, instead of leaving it all up to the private sector.

We spend tax money on defense because it's a public good and in the absence of tax dollars there's no money in it. The same applies here.
http://www.urx.com/ would be one.

techcrunch.com/2014/04/28/mobile-deep-linking-startup-urx-raises-12-million-launches-universal-link-service-called-omnilinks/
To be honest, a little example like that might be perfect. Maybe I'm not the right target audience but I was hoping for that sort of exploration of how disparate information sources could be made to work together.
Tier 1 is definitely the way to go - on the site I run, which I see as being great content with a high-value audience, we can direct sell an ad for 6-8x what we'd pocket from Google for the same real estate.
What does this offer over using Google Scholar's citations?
Google might be able to weasel out of a patent suit because they don't sell Android or because phone vendors might modify Android to remove the feature in question. With Samsung it's easier to identify specific infringements.
w/r/t/ interviews, I would say that the outreach programs are less important than standardized interviews and work-sample tests.
Lies our bubbles taught us
I got my current job with linkedin. At least for those looking for a job (which is the only moment I update my profile), I can't see why adding new options to your job search can hurt.
Very cool. Would have saved me a ton of time.
Ah yes I missed the second for loop to get the location.
Doesn't matter. If you're the first one to get a patent, it's all yours. There's no provision in the law for independent invention.
From one perspective this looks killer: It looks like it supports a long-time pain of being able to direct someone to download an app and then open a specific location within the app. You could now have a QR code that when scanned from a shop didn't just download the right app for the phone, but the applink would also describe what to open once the app is installed.

But from another perspective this looks like a nightmare: It entrenches apps as the universal interface, and not the browser, by keeping people within the world of apps.

I can see why advertising companies want this, the browser is a battleground for control of the presentation layer (adverts) and apps help protect that (by locking out adblock add-ons, etc).
> The listed shortcomings all sound like features that over time should be developed by Twitter. Assuming those features are value adding.

Surely. Right now there are 5 different services one has to use in order to get the stats.

> Might work in the short term but long term the odds of survival are low.

FB page analytics products seem to be doing just fine. One product does not fit all, so if someone has a good product offering, a bunch of people are still going to use it. E.g. Kissmetrics vs Mixpanel, they do the same thing, but appeal different audiences.
The difference does not primarily stem from raw interpreter performance but rather from the different community mindsets and resulting ecosystems.

The average code-quality in rubygems is just not very high. Consequently most libraries are completely oblivious to performance aspects.

This reaches straight into the core infrastructure (rubygems, bundler) and all major projects (Rails). Leading to the simple fact that Ruby loses out on many practical benchmarks before your script has even loaded.

Likewise the synergies of less than bright behaviors from all the gems in your average Rails project (and no least Rails itself) do indeed make the performance gap towards an average django project much larger than the mere difference in sheer interpreter performance.

That's all not meant to bash Ruby anyway. It's a trade-off me and many others are willing to make, for the convenience that ruby provides after it has finally set its fat belly into motion.

But let's not pretend these differences don't exist when everyone who has ever used both languages knows them all to well.
The "most consonant" is Pythagorean for the simple fractional intervals, so you'd have to weight somehow against that.

I'm using "minimum number of beats" as the definition of "consonant".
SEO is on the way out, and AdSense is too expensive. Social media is the new SEO, check out this book for the insider tips: http://massivefollowing.com
I recently split my ads (50% AdSense | 50% Media.Net) on one of the blogs I maintain and they both earn very close to the same amount every day. I like the service.
Let's not conflate unit testing with integration testing. SQLite should, in most cases, work just fine for unit testing.

First off, many people would argue unit testing should never really require a database. I'm not of that opinion, but I'm not writing CRUD apps, and since there's not really a SQL unit testing framework, using SQLite is a nice compromise, especially as unit testing should necessarily be limited in scope.

Integration testing should definitely be done on a system that is in parity with prod.
Care to justify that assertion? I think OT is a fantastic way to deal with partial order.

OT can be used to guarantee eventual consistency while preserving intent. And unlike transactions, it lets you edit your local model syncronously in the client without waiting for a server round-trip. When you have a stack that can do it, its a really great system.