skysight-inc/HackerNews huggingface dataset:
The NRE and storage for additional samples isn't that much cost - now. 20 years ago, yeah. Cost is way dominated by the number of parts in the MIDI controller used.

Piano sample sets can now run into the gigs of memory - a now-defunct product that pioneered this was actually called Gigasampler.

For a file format that describes how samples relate to MIDI notes, google for "SFZ files".
Don't know about that. Those National rice cookers that the OP mentions are simple and extremely reliable. My parents, even though they upgraded, still have two of them in storage, and they work to this day. And they've had them as long as I remember, which would put them around 40 years old.
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The best thing you can do is keep informed, and keep others around you informed. Many people don't realize this is such a rapidly progressing issue. In fact, many people may not even know that they are improperly taking their Antibiotics and what the side effects are to doing so.

If more informed I feel like the public could do a bit better at turning down Antibiotics when they aren't necessary, and using them properly when they are. Just that action would go a long way.

Edit- I would also like to add that a lot of people don't realize just how easy it is to get an infection, and education could go a long way in keeping it from happening in the first place. It reminds me of that guy on reddit with the horrible case of necrotizing fasciitis that he ended up with after retrieving a football from a koi pond. His day by day imgur chronicle was both interesting and horrifying.
Sprinklr Teams Up With Iconiq at $500M-Plus Valuation
The general criticism focused on here is "mechanical processes". At first I misread this as a focus on literally mechanical machines that did something. But now I understand it as demonstration of performing an algorithm used to solve a particular pattern of problem. And the core of the criticism is that knowing the algorithm doesn't mean you understand the algorithm, and could modify it to solve related problems.

However, that criticism doesn't have much power for me, based on how I understand I learn. I like to learn from two ends; one, from above, with an overview of the space, so I know where the next bit fits in. And from below, with concrete examples - yes, mechanical examples - of the individual steps. I infer the deeper structure of what's being taught as more and more variants of the mechanical process are shown.
Oddly enough, I can't find a single reference to farms using antibiotics as a growth enhancer in this article. Isn't that the single biggest source of antibiotic-resistant bacteria?
Oh, you'd like more?

How about simple closures:

function getCounter(){
var num = 0;
return function(){
return num++;
};
}

How about overriding default functions? This is a snippet from a codebase I'm working on right now:

require(['helpers/user'], function(User){
// hack because we are not using layout.master
User.isLoggedIn = function(){ return global.userInfo.id > 0; };
});

How about re-using some code in a function? Another snippet from the same code, where self can change based on context:

var inCart = function(){
$(self)
.addClass('disabled')
.text('In Cart');
};
if (Cart.isMixIdInCart(results['mixId'])){
inCart();
}else{
$('.widget .purchase').on('click', function(){
$('.widget .purchase').text('Adding');
Cart.addToCart(results['mixId']).done(inCart);
return false;
});
}

These are simply different ways to use closures, but that's part of the benefit of using anonymous functions.
Antibiotics work on a specific mechanism of action.
See here: http://en.wikipedia.org/wiki/List_of_antibiotics

New mechanisms of action are needed, more specifically, mechanisms that evolution cannot biologically defeat. Consider an agent like bleach, 99.99% effective because the makeup of a cell does not really permit it to protect against such a caustic agent. Clearly bleach can't be used as an antiobitic but I use it to illustrate the point that a evolutionary-unlikely antibiotic mechanism would be worldly profound.
I hope SROs in San Francisco get as much administrative attention as short term rentals. Decade old legislation severely hindering the development of downtown SF.
I generally like what Khan Academy is doing, but it is definitely not a complete replacement for the classroom.

What you are seeing is a blowback against the traditional classroom. Our school systems are so poorly run, that a guy with no teaching experience can create something insanely popular in the education industry.

Why didn't a classroom teacher do what he did? Because our system does not reward teacher innovation and trying new things.

Our system rewards obedience and conservatism.

Our teachers (like our students) are taught to conform and do what the admins want. Those that don't are punished, sometimes directly, but most often indirectly.

Poor salaries and bad working conditions mean the best and brightest do not become classroom teachers. Or, talented people who are classroom teachers bolt as soon as something better comes along.

There are some high quality people who teach, but they are browbeaten so often that it turns the young, dynamic person into a cynical and slightly depressed professional.

I don't have all the answers, but I do know it isn't more of the traditional classroom.
You submitted this an hour ago, but I see it's been deleted. I believe, but cannot find confirmation, that the moderators frown on this, and may in the past have banned people who submit, delete, re-submit items. Such a ban might depend on just how flagrant the behavior is, and the occasional cycle may be tolerated.

I do not speak for the moderators, and this is my understanding only.

Edited for clarification of the lack of documented source.
Isn't this caused because some countries make antibiotics easily accessible without a doctor?
>> "Whilst I totally appreciate the seriousness of this, I still don't get what exactly I can do about this. Most likely, nothing."

I think you can help by informing others. If you know a family member not completing their course of antibiotics for example explain to them why it's so important.
Re-use them for shipping out the finished product, so they become someone else's problem.
Isn't (one of the reasons) this due to excessive use of antibiotics?
If your doctor is prescribing you an antibiotic, you can ask them what the pros and cons are of taking it. If you are willing to deal with the cons, then maybe don't take the antibiotic. Usually, the con will be that you feel sick for a bit longer. Note though, that you might need them to get over whatever it is you have.
Is there any particular reason we can't just create new antibiotics? Is there something inherent in the current design of antibiotics that prevents creating new versions of what we have? If so, is there an 'upper limit' of how many we can create, and have we reached it already?
If you're in health/fitness/nutrition/diet, we have some tools using the PricePlow API. Buzz me if so and good luck!
My concern with this line being drawn is the risk of people drawing a line between them and then transferring the overwhelming amount of skepticism of climate change to such a serious topic as this. All we need is to give the anti-vaccine nuts another reason to shit all over herd immunity.
That's a pretty wild claim; what observations have led you to this conclusion?
At some point, you will find you have bugs in the tests. It isn't like that code is magically immune to mistakes.

Not to mention you have increased the workload of everyone just to mitigate the impact of additional code. Let me know how that works out for you. :)
SHOW HN: Simple, fast, effective Promises implementation for learning purposes
Senate fails to advance minimum wage hike
> As a hiring manager, I expect candidates to have a LinkedIn profile that is up to date.

It's nothing personal, but if I ever encountered that while job searching, I would turn tail and run.
Do you have a link to that, per chance? It seems like reasonable behavior on their part, but I've never seen it in the site guidelines, nor mentioned in a comment.
Facebook F8 Announcements – anon app logins and more
I will echo lucky's sentiment - staying educated, and educating others around you, goes a big way. I know people very close to me who still believe it's okay to stop taking antibiotics the moment they feel better, rather than finishing out the entire prescription.

I'd like to believe that buying meat / other foods that aren't treated with antibiotics could make a difference as well, but I'm not sure how much impact that would have.
Nope, was unaware. Sorry...
That's a fair point. In this case I was especially interested in running multiple instances of the same application on a CoreOS mini-cluster, demonstrating fleet's capabilities of scaling/distributing the containers over the cluster.

However, in a real life application I think I would still keep the containers as "single-process" as possible; in our case that would mean: a single Rails application or a group of Resque workers. It would make the containers quick to boot and would increase security by sandboxing all the separate parts of a system in their own containers. I do think this is up to personal preferences, though :-).
The process is the unit in which things fail in an OS, so a collection of processes needs to do its own failure handling. Part of the point of these types of system is to do things like failure handling, rather than everything having to do its own.
Oh woosh! :)
So every few weeks we get these news but this isn't reversible anyway i guess. Does this basically mean a lot more people will die from simple infections starting 1-2 years from now ? How likely is it that new antibiotics will be developed ?
By reading articles like these it sounds like we are facing a massive increase in deaths from illnesses, yet the general public doesn't seem to care much. Genuinely curious.
Also as a hiring manager, I DON'T care if you have a linkedIN profile. I do care that you can do the work required well and that you'll be a pleasure to work with.
In related news, Facebook announces a new definition of the word 'major' :-)

Ok, that is a bit snarky. I think it is a great policy for organizations to commit to this level of response. The tension is that to execute against that policy requires a proportionate number of employees on 'bug fixing' rather than 'feature delivery'. Source bases grow, technical debt increases, and at some point you can't afford to hire any feature delivery engineers, all of them have to be on 'bug fixing.' Then the policy collapses. At the time I was there, Google tried to address this eventuality with 'fix it' days where everyone fixed bugs (big or small) all day. They would have prizes for the person who fixed the most bugs (you could really irritate someone by fixing a half dozen really easy bugs on the day before the fix-it :-))

When you're growing a company and you push/reward "Get things done" or "Move fast and break things." it often accumulates technical debt faster than you can purge it out of your system.
I use LinkedIn, but it generates way, way too much email. Now I have a filter to send all LI mail straight to it's own folder. Next step is straight to spam.
And here's his retort to these brash blog posts attempting to portray him as sinister: http://www.salon.com/2014/04/11/michael_lewis_hits_back_at_c...
Matt, correct me if I'm wrong, but you work in a completely different department to Adsense & therefore it is quite possible that you are completely unaware of what takes place with Adsense.

1. I think you will also agree that the Internet is riddled with stories of publisher accounts being closed down prior to payout & without any explanation whatsoever!

2. Google's own webmaster's forum is brimming with questions relating to the mismatch between traffic figures quoted by Google analytics & other 3rd party software.

3. And last but not least, we all know that it is nigh on impossible to contact Google direct & get a straight & sensible answer to any question pertaining to your Adsense account! (Not what I'd call transparency)

Personally I think there is more than enough here to cast doubt & if Google wants to be seen as squeaky clean, then investigation by an outside authority is going to be the only answer IMHO!

Taffy
Not sure why swombat got downvoted, he makes good points. Heck, once in a while, an HN submission for along the lines of "Why reading news is harmful and why you shouldn't read it" goes by, and it gets upvoted a lot.

What can the general public do about this? It's not like I can go to my family physician and tell him to use less antibiotics (he already doesn't; I'm in the Netherlands), and expect to make any kind of meaningful difference. This is one of those "tragedy of the commons" kind of problems that can only be solved if everybody cooperates.
They're not necessarily a bad candidate, but I have a lot of resumes to scan and this metric works most of the time. I'm okay with getting it wrong sometimes.

I didn't intend this to be taken as a personal affront to people who don't use LinkedIn, so I should have used less inflammatory language. My apologies.
You're welcome! I'm now looking into log aggregation and centralisation with Logstash and logstash-forwarder (previously Lumberjack). So expect a new article on that in the near future.
How a 4 dan go player thinks about A/B testing
I submitted this yesterday under the current URL, so that probably would have failed. I think a lot of people submit alternate URLs for articles that failed to get traction due to bad timing or whatever.
It's an active research topic, and little progress has been made recently.

You'd have to find a new class of drugs that is safe for humans at the toxic dose for bacteria.
If BATS has the best price or matches the best price available in the market, your order will execute at BATS. If there is a better price available at another market center displaying a protected quote, BATS has to route your order to that exchange.
Yes. It provides a lot of information about the history of science. Most importantly, Grosseteste was one of the first to use what we now think of as the scientific method, and (I believe) the first to suggest a 'big bang like' start to the universe.

He's essential in the history of science for introducing aristotalean traditions and ideas, to the scientific discourse at the time, as well as being one of the early founders of science. For that reason at least he's well worth studying, and especially his ideas, which are very close to what we have now. What the science researchers are doing is helping the historians formalise his ideas in todays language and notations so that their similarities can be seen with todays ideas.

Source: I worked on this project over last summer as a computer science student visualising his explanation for the start of the universe.
So I cloned and installed it... And I'm running the example. However, I'm really not sure what I'm looking at here. http://i.imgur.com/xMkV1Qg.png

Can anyone explain?
I disagree entirely. I put my projects on my own site. I see no reason to put then on github in any way shape or form. What will it offer to me that my site does not?
Interestingly enough I did about 50 problems of PE in Javascript (no libraries except my own custom written helper functions) to see how far I could get. Output was simply writing to the browser.
I'll check - it may have been mentioned to me separately when I was talking with the moderators about other things ... stand by.

<fx: pause />

Back again. I've gone searching and I can't find a comment here on HN via the search function, so I suspect it was a comment made to me by one of the moderators.

I have edited my initial comment to make that clearer.
To expand on this a bit, you can source a file to expose variables to your unit. On most providers, CoreOS populates /etc/environment with the public and private IP. You can then use those as env vars in your unit:

[Service]
EnvironmentFile=/etc/environment

You can then use $COREOS_PUBLIC_IPV4 anywhere in that unit file. Makes service registration a breeze.
Site where you can generate random data
The Nomad VC: a16z’s Newest Board Partner Boris Wertz
Equal Temperament is an abstraction - different instruments will have an entire discipline of temperament. One of the more complex suites of temperament regimes are the temperament regimes used on pedal steel.

Getting a steel to "do" ET is actually an achievable engineering problem, but players may prefer the sound of something more akin to Just intonation and older guitars may not be able to be in ET. Guitars with all the parts to achieve ET are relatively obscure.
Why can't you challenge the legitimacy of the contract? Not every contract stands up to court scrutiny.
my favorite:

/*

Yeah, there's some shitty code here.
There are some things that shouldn't
be done. I did them. Sometimes, I had
my reasons. Sometimes, I was just being
lazy. But guess what? You're sitting
there reading the source on some guy's
blog. So fuck you.

*/
That depends largely on who you ask. I don't eat most of those foods. And corn?
And Kluge agrees with my intuition that modern German "Rest" also comes from Latin (restare, 'to remain').
Be educated about it, and educate others. Eventually, you will be called on to vote on something, and some intrenched interest will try to convince you that it is an encroachment of big government on the sovereignty of job creators. Good luck trying to teach them then.
Editing is disabled a certain time after the comment is posted, perhaps that is what you have observed?
This looks like a bug. I can see the guy's profile just fine as a registered LinkedIn user.
Many CephFS features are directly tied to BTRFS features.
So has the cheap clone keyboard linked here https://news.ycombinator.com/item?id=7671321
> That is why this practice should be banned.

Which practice, exactly? You described one party having a faster connection than another. That's not exactly something you can "ban". Lewis even acknowledged that relative inequality of this nature will always exist.
U.S. Government Is Turning Seized Silk Road Bitcoins Into Cash
This is useful, but a good portion of these recipes aren't useable in an office environment. Curious if anyone has something similar, but where are you limited to, at most, a microwave and/or toaster oven.
The reason is that creating antibiotics is not profitable enough, and so 15 years ago pharmas stopped most research on them.
I just setup a linked in account recently. Felt like I didn't have much choice.
Donate to research groups that are working on ways of controlling bacterial and viral infections that are a step beyond the present status quo. Things like DRACO [1] spring to mind. Present day fundamental (as opposed to translational) biomedical research is very cheap in comparison to the state of things even a decade or two ago. Small fundraising groups can make a big impact now.

[1]: https://en.wikipedia.org/wiki/DRACO_(antiviral)
They don't bring anything new in the same way a repl doesn't bring anything new to a edit/compile/run cycle. Instant feedback is just better.
Both are pretty serious topics.
>Gandi has a morality clause in their ToS; there are any number of good, cheap registrars that don't, so I'd say go with one of them instead.

Thank you for highlighting this!
I agree. I recently had to take antibiotics for the first time in as long as I can remember. Without them I probably would have been in significant/debilitating pain for the foreseeable future. At the same time I happened to come across a really long detailed article about antibiotics explaining about the dangers of resistance and life before antibiotics. If we don't fix this or find an alternative solution we'll essentially be going back in time in our health care.
Apparently not. This article (http://www.telegraph.co.uk/finance/newsbysector/pharmaceutic...) suggests its a case of economics. That is new antibiotics would be kept back as a last line of defence only; therefore not as profitable.
Here's a link to Facebook's blog post:
https://developers.facebook.com/blog/post/2014/04/30/app-lin...
I have long thought that humans (at least those living in the first world) had developed civilization to a point where natural selection was not really operating anymore. We can shelter ourselves, feed ourselves, and cure illnesses and injuries so well that almost all of us live to reproduce and raise our children to the point where they can take care of themselves. We haven't even had a large-scale war in the time that most of us have been alive. But on evolutionary timescales, we've really lived this way for only the blink of an eye. So maybe I'm wrong. This is a reminder that we live in a larger ecosystem that we really have a lot less control over than we might think. Nature has a way of keeping things in balance, and it's never pretty.
How is the pressure difference in passenger plane toilets generated?
Well, there is a parallel. Not being on Facebook is very odd, so it's pretty rational to expect the person to be odd as well. In my experience it's mostly a privacy thing. Not a well-developed opinion necessarily, just an instinctual mistrust to orgs that collect lots of personal information.
Well technically it's more like the humanities people asked the physicists to help them interpret his ideas using todays scientific language. If you read Grossetestes original writings, even when translated into english, they read very differently to how any modern scientific theory or description would. So really, the scientists are helping the humanities people examine his ideas through the lens of modern notation and prose.

Source: Worked on this project over last summer as one of the scientists, developing 3d visualisation of De Luce.
Because people who know HTML and CSS don't know how to set up or manage a database locally. Even worse, they'd have no idea how to port that data onto a live production server. Firebase makes the install pretty painless. Our only dependency is Node. Right now that means even windows users can get up in running in less than a minute.

As a designer I really like the ease of systems like Jekyll, but it was a dead stop as soon as I wanted those sites to be editable by other users. This way we get the best of both systems.
Yes; there are perverse disincentives built into the profit mechanism underpinning the commercial pharmaceutical industry.

Patents on antibiotics last no longer than on any other type of medicine (20 years, minus the substantial time taken to test it, jump through regulatory hoops, and bring it to market -- typically 8-14 years). The cost of meeting those regulatory prerequisites is measured in the hundreds of millions of dollars in the USA alone -- more if you want to get a product license everywhere worldwide. So you need to earn back several hundred million bucks in profit in a single-digit period of years ...

But antibiotics are unprofitable. A typical AB course lasts 5-14 days after which the patient is completely cured. Compare with antidepressants or ADHD drugs -- where you get a customer for life! Which would you invest in, if you were in that business -- a product 10% of the population will use annually for a week, or a product 10% of the population will be hooked on for life?

It's not a coincidence that research into new antibiotics ground to a halt in the 1970s around the time that the regulatory barriers to entry rose so high that small and medium scale pharmaceutical companies were frozen out of the business and the surviving operators were the large conglomerates.

(Disclaimer: wearing my ex-pharmacist hat here.)
I think #6 is too vague. Specify that the time is for working on personally-defined long-term projects. Investigating a question, experimenting with toolsets and devices like car engines or old computers, constructing and practicing for performances like theater or poetry, etc.

I also think an effort should be made to bring in volunteer teachers from the professional community, but that's a harder task.