skysight-inc/HackerNews huggingface dataset:
Are you sure about that? If you get 1000 people to pay $100 for your "product" that you don't ship to them, that's a pretty good profit. You can just walk away with the money, never to be seen again (under that name at least). How the economics would take care of that is anyone's guess.
URX (YC S13) is hiring builders and sellers to rethink mobile app advertising
I also had a similar issue trying to set up a fedex account over the phone. I couldn't do it online because their site was down. I called over the phone and they made me answer a bunch of questions from over 10 years ago. Since I missed 2 questions they refused to set up an account for me, and refused to ask a new set of questions. It was infuriating.
congrats guys. I love that you can run experiments without having users update apps.
I couldn't find a point in the article where it explained why it censored 'fuck' in not only the title, but everywhere in the article body. It's not particularly compelling evidence that given advice works.

Say 'fuck' or don't say it. Don't censor it - you come off as weak-willed to everyone, because either you're too weak to actually say it, or you don't have the wherewithal to find one of the plethora of other ways to give the same opinion.
I think I'd have to offer that my experience differs. TDD is not at all big-design-up-front, even with this reductive exercise. In fact, most features start very minimally and the tree of dependencies grows over time, just like any system becomes incrementally more complex. TDD is just one tool (of many) to help manage that complexity. Both by offering some regression value (at least of the logical bits) and also by encouraging small, bite-sized units that are easy to make sense of (and therefore change or replace)
http://www.mediaite.com/tv/ted-cruz-goads-eric-holder-into-a...

I think I'm done with this argument now.
This is pretty amazing. Congrats, I think this will be extremely useful to a lot of apps.
Ask HN: Is setting up a remote team of developers in India worth it?
Market wages are currently dramatically lower. Potential hires seem to speak really good English considering it's their second language. I still want to make sure there isn't some kind of catch!
I'm used to using Native Instrument through Wine but I'm sure native Linux support would make it much easier
identity verification of small merchants is a really hard problem to solve with 100% accuracy. (or even 90% accuracy) At WePay, we use Facebook identity to help supplement KBA. It's not 100%, but does dramatically increase success rate.
DeepMind to Work Directly With Google’s Search Team
I am seeing some parallels between how Paypal operates and deals with their customers and how Square deals with their customers, you know the ones that make them profit from the fees they charge for using their service? Sadly, this is how big commerce works. You try and try to get a human response and you're met with the old favourite, "Our decision is final" nonsense.

I recently encountered this with Electronic Arts and their Battlefield 4 game. I forked out about $150 AUD for the base game and premium addition only to be informed my account has been permanently banned after coming back from a month in Europe on holiday because they said I was cheating. Well actually, they wouldn't give the exact reason, but that was essentially what their response implied. When I asked for whatever proof they had, they said our decision is final and we can't show you any proof.

I am in the process of getting a refund as I paid by credit card, but this is definitely a commonly recurring theme amongst larger companies who struggle to deal with their customers and ultimately retain them. What kind of business model punishes their customers?

Good luck, I think you have a real chance of getting some human response now that this is on the front page of Hacker News. My understanding is that this is how people get responses from people over at Paypal as well, create a loud enough noise for someone higher up to respond as to avoid a PR nightmare and get your problems resolved.
seems like it would be tough to file a complaint for them not letting you process. I would imagine that right (to deny your business) is spelled out in their TOS (something, which in my experience@wepay, is something that regulators fixate on).

if they were holding your money without a schedule of release, that would probably be a stronger ground for a complaint.
Design Patterns in PHP: Singletons
What I know is that the quality of their code is very outdated and even being cheaper to hire you are going to spend lots of money fixing the code.

Nothing like having quality code!
It's meant to be used while you're already playing Magic the Gathering or another other card game, as opposed to using dice or paper
If only they had an android app that would sync directories!
The definition of a vaccine is that it is preventative vs. a cure which is removing a disease from a previously infected patient.

"A vaccine is a biological preparation that improves immunity to a particular disease."
This "other people aren't thinking about you" thing - I hear or read this every three seconds. It's a chestnut. Yeah, there's some truth to it... sometimes... maybe? It depends who and when? I know that I spend a lot of time thinking about other specific people, and I can't be the only one on the planet who does. I think this tired advice is more of an "act as if" thing.

Either that or the rest of you are far more self-involved than even I thought.
Well the US govt has been saying that Huawei kit could not be trusted... I guess they were right...
>Sorry about the delay. Took me a while to wipe the vomit from keyboard

Not nice.
I've always found it odd how the lotteries do that. Win X Dollars. You can take it now as X/2 dollars, or you can take the 'whole thing' annually for the rest of your life in small amounts... where they mean less over time due to inflation... and you have to hope that the entity paying out is still around decades later. There doesn't seem to be a way to take your winnings in a way that preserves the purchasing power of those winnings at the time they were won.
(3) Try Shopify's POS. I do not work for Shopify and have never used it so I cant speak for it beyond its advertised features. I have been comparing POS's lately and Shopify is cheaper and has an API to allow you to manage your inventory or allow others to make tools to help you.

(4) If you research any other POS's reply here so I can see. ;)
I don't take any test or poll unless you tell me ahead of time I won't have to give you my email address or facebook login or any of that crap to get the results and unless you give me a true and realistic understanding of the test's length and the time to complete it.
There are two kinds of companies: companies that are big enough to be immobile on this issue, and companies that aren't big enough to take on fixing the US's consumer finance infrastructure.
This is also a representation of where the power and profit sits within the industry. If apps were subservient to people in the UI, it would be trivial to replace them. However, successful businesses are built through preference over competitors. These businesses pay the wages of people who design systems and services that achieve this. The app stores continue to feed the platform makers and that's where we end up.
Thanks, are you saying they tend to be lower quality coders or just outdated coders? Maybe you're saying both. We're talking as more or more than 80% worth of discounts in compensation packages when compared to American programmers.
Honest question, what exactly is easier "to use"? Most hosting configs have php installed, to write a program you just code and save it as a .php, basically made for Mysql, and you have more documentation online than probably any other server side language.
I suspect this thread is dead but if you're still watching it I'd be happy to take it up over email :) (see my profile and shoot me a quick note).
Apparently your comment is being derided because you criticized the guy for wearing makeup, but I think your overall point is quite valid. Prosecutors that are more interested in self promotion than justice are not a rare thing. I'm more curious in peoples' ideas for how we could disincentivize this type of behavior.
Another thing I want to point out is that your home page touts safety as a design point. The text under "SAFE" says "Our vaccine does not contain killed viruses, live viruses, or genetically-modified viruses." I STRONGLY object to this language as it implies that inactivated (killed) and live* viruses are unsafe in general. This is simply not true. I believe most clinically used vaccines are either inactivated or attenuated.

I understand that you're trying to make sure people understand that your vaccine is safe. However, implying that other vaccines are unsafe because they are inactivated or attenuated does a disservice to the entire vaccine industry.

*I think you mean 'attenuated' here, not live
Hi there, Reid from Immunity Project. Thanks for the great question! Would love to talk with you off line about your research, by the way.

1. We have successfully gotten an immune response with memory (by elispot) after a single dose of the PLGA microspheres containing one or two peptides when combined with TLR-4 (MPLA) and TLR-9 (CpG) agonists. We used H2d restricted epitopes to do the study in C57BL/6 mice – this study is done and in the PRJ review process. We are being careful about posting the results in the event we need to re-submit to a journal who would get heartburn if they saw the data posted.

2. We are raising money now to essentially repeat the experiment (on a smaller scale because we think we understand the optimal formulation configuration now) in C57BL/6 NOG mice (with human PBMCs grafted in from a donor with known HLA type). The new experiment starts off looking like the experiment in (1) above: intradermal tail injection, wait 14 days, sacrifice, get the spleen, confirm immune response to peptide target by flurospot. The next part is new: separate CD8 from CD4 cells (from the mouse spleen), infect the CD4 cells with HIV, see if the vaccination attempt was good enough to see p24 antigen suppression and/or a change in the CD4 counts (all in-vitro). We can finish this study in a couple months, assuming the crowd funding keeps going well and we start in a couple weeks. We will use a different mechanism to publish our paper around this experiment so that we can get it out right away in a fashion that will lead to peer review and open access (We just learned about peerj.com – thoughts on that?).

Looking forward to hearing your thoughts on our approach.
agreed, I didnt have to look far at all: affect / effect are (and sound) completely different.

also as an aside, both effect and affect are both verbs and nouns.
1: The head of state of one of the G8 would have a reputation easily worth half a billion dollars. Not in terms of personal income, but a damaged reputation could easily cause havoc in billions of dollars worth of various political deals.
I've been having issues compiling the last 2 versions of nginx. Anyone else seeing this?

make -f objs/Makefile
make[1]: Entering directory `/home/newman314/src/nginx-1.5.9'
cc -c -pipe -O -W -Wall -Wpointer-arith -Wno-unused-parameter -Werror -g -march=native -Ofast -fomit-frame-pointer -fstack-protector -D_FORTIFY_SOURCE=2 -I src/core -I src/event -I src/event/modules -I src/os/unix -I objs \
-o objs/src/core/ngx_string.o \
src/core/ngx_string.c
{standard input}: Assembler messages:
{standard input}:1253: Error: no such instruction: `vfmadd312sd .LC5(%rip),%xmm1,%xmm0'
make[1]: *** [objs/src/core/ngx_string.o] Error 1

Configure flags used:
./configure --with-http_ssl_module --with-http_spdy_module --with-http_gzip_static_module --with-cc-opt='-march=native -Ofast -fomit-frame-pointer -fstack-protector -D_FORTIFY_SOURCE=2'
So this is what millions of low income, undesirable customers face every day when they try to join the financial system by opening a checking account. What OP has experienced is the next iteration of that. What happens to society when the gatekeepers of our technologically enhanced future decide for some arbitrary, non-appealable reason that you are an undesirable and you may not participate. Everything from accepting payments via a dohickey on your iphone to even having an iphone. Or maybe the internet. Maybe you can't have the internet cause the we say so authority says they don't like the neighborhood you live in or something that was in your credit history.

I'm getting failed on a similar knowledge based identification on coinbase right now. Failed twice already. At least it's not a final decision, to their credit.

There needs to be laws against this almost certain dystopia. That's one reason why I support the EFF.
> They only banned me from accepting payments. I can still use them to pay at any establishment that uses Square

Other than that, Mrs. Lincoln, how did you enjoy the play?

I agree with the GP poster, I'm at a loss to comprehend why you continue to "enable" companies like this to continue bad business practices.
http://release-technique.com

Improves all aspects of your life, not only that.
we do, but on the hybrid cloud for now. We'll have it in the private cloud soon
I love C. It wasn't my first language to jump in to, but it was eye opening to see the power of pointers and low level operations. Java just couldn't get me close enough to the system.
Intel debuts $141 power-efficient NUC mini-PC
Time to take off the tinfoil
Ian from Immunity Project here. We've actually chatted with a few of these large foundations and they are very interested. They want to see some Phase I data first, so that's why we went ahead with the crowdfunding campaign to help us get to that point! Check it out: http://pledge.immunityproject.org
This looks like a pretty good summary. The stylistic way it's written as if about a 'foreign' language sure makes me feel old though. Twenty years ago, this was completely normal. When I went to work, the code was this. This is what there was. It wasn't "low level" or esoteric - just a nice language to feed through the compiler to get executable code.
How A Crappy User Interface Can Create A Privacy Nightmare
This article states the NSA developed an exploit for a product made by a Chinese networking and telecommunications firm. Honest question for HN readers inside the US: does anyone seriously have a problem with this? In my mind it falls squarely within the NSA's mission, i.e. this is we pay them to do! Question for HN readers outside the US: can you credibly claim your intelligence agencies aren't trying to do the same thing?

For those thinking about whether such things could be used inside the United States. Of course they can. So can all the equipment and weapons the military buys. And it's happened before! The gun in the Fort Hood shootings was bought and paid for by US tax dollars and it was used to kill a civilian. So this raises the question, is the military to be trusted with weaponry it needs for its defense mission even though they could be used in the US? Similarly, is the NSA to be trusted with exploits it needs for its SIGINT mission? Interesting question. An infantryman could go rogue at any time and use his service weapon against US citizens and someone at the NSA could use an exploit for personal gain, but on the whole I believe the system accounts for these possibilities in a reasonable and controlled way.

If this information is true, it seems a little crazy to me to be propagating it since there isn't really a domestic/whistleblower angle. At least, no more of a domestic angle than the military developing a new missile. Some of Snowden's disclosures are responsible for starting a productive civil liberties debate in the United States, there's no denying that. But these disclosures are ones of a different color in my opinion.
Same exact thing happened with Dwolla. Couldn't figure out if the identity verification service used my old address, current address, or my parents' address. I'm still locked out...
I was always a fan of GURPS for this reason; well, that and I think the distribution of a 3D6 roll is pretty great.

You're given a pretty simple core, without much of any fluff (so lite you can get it free [1]) and then you're free to add any number of source books to your library to add more depth, or change the game more toward the direction of your liking. You can even play in fully licensed environments with fully licensed sourcebooks (like Vampire [2], etc).

I wouldn't say it's the perfect pen and paper RPG, and choosing the 'best' one is probably even more subjective and flame-war-inspiring than picking the 'best' programming language, but it fits my philosophy of gaming pretty well. I would say, though, that an RPG has a pretty direct goal to me, which is having fun. I throw out what I want if I don't have fun with it. I think the mistake is blaming the creators and saying it's stupid, which would just be kind of silly. It just doesn't fit my paradigm. That said, I've played god-knows how many pen and paper RPG's and I have a really good understanding of which paradigms I do and don't like.

I think that's how I generally approach programming languages as well, though I'm not as adept with programming as I am rolling a six sided die.

[1] http://www.sjgames.com/gurps/lite/
[2] http://www.sjgames.com/gurps/books/vampirethemasquerade/

(p.s. c.y.a. this is seriously not serious but kind of serious so ymmv)
"the length of the array isn't stored in memory anywhere"

This is probably not true. For arrays on the heap, the size (or an approximation e.g. number of pages the array spans) would have to be stored somewhere in order for the array to be deallocated. For arrays on the stack, the size is either known at compile time, or else it was at least available when the array was allocated and could be kept in the stack frame (and in many cases would be kept in the frame anyway).

Not only that, but the common pattern of passing a pointer to an array and its length as arguments to a function implies that most of the time C programmers keep the length of the array stored somewhere. You are really talking about niche cases where the length of the array is truly and inherently unavailable.

Really this has more to do with the fact that C is meant to do as little as possible for programmers -- it is supposed to be "close to the machine."
I don't see this "people-centric UI" idea as anything more than a glorified address book. And I never use address books, so I don't see why I'd be attracted to a people-centric UI.
Thanks for the comment! We did not mean to imply that existing vaccines were dangerous and will modify the language on the site to clarify.
I didn't miss the point, I was being flippant in that they can call it what they like and there is little you can do about it, you can call it extortion among your friends but that doesn't change the outcome. I also think you're forgetting what service they're providing. If you aren't paying anyone for protection then anyone can rob you and no one will be enforcing consequences on them for you as you have no protection, anyone can break contract with you as you have no option to enforce the contract. Maybe you're rich enough to hire a personal bodyguard but the majority of people can not. The majority of people effectively have to pay this “service” fee or move or be insecure in their possessions.

Why doesn't another competitor enter the market? Well considering the market the competitor needs to be big enough to stand up to a literal attack by the incumbent. In the best case the incumbent and the newcomer both end up being about the same size and they compete. Alternatively as this hypothetical investor who has the capital to get about half of this large market I would do better spending the same investment on a smaller market were I can capture the whole market and force a higher percentage return on the investment. You can look at comcast/time warner to get an idea why these two big encumbents might not compete even without forming a cartel. If someone was to point me at google fiber as an example of how the market will be disrupted I'd point out the fact that the local companies are trying to use the legal system to thwart google fibers growth even within the city and if these companies were the enforcement of the legal system I don't particularly believe google would get a fair shake of the stick.

What could be worse? What could be worse than conducting a theft from people calling it a service fee, then be bribed by corporations and not delivering the service to serve a corporate interests? Simple math: a company pays (it's not a bribe it's legal) the protection company with $1, the protection company allows $10 of somebody's stolen property to be used (so it doesn't cost them anything) for that company and that makes the company $100. In a system with a democratic government, the official has to at least pay lip service to working for the public good and it's illegal to accept that payment.
Wait! But what HIV protein(s) is the peptide(s) derived from?

Let's not overlook the decades of prior data! The field is littered with names like VRC01, Camelid and so many other players. I know, I know, antibodies all versus antigen in this case. But keep reading ...

HIV is a master at developing resistant forms of itself. What if it changes the epitope and evades the vaccine induced antibody(ies), again!?! (Edit: Don't forget the long-term viral reservoirs that survive against the best antiretrovirals known to us!)

This is something I care about personally: What is their strategy against resistance? (Or, like everyone else before them, they will build that bridge when the water is above their nose!?! Not being snarky, just very concerned.)

And might I also ask: Any concerns about accidentally inducing an autoimmune disorder with that antigen/epitope?
Why/why not?

Added: I'd love to see these guys succeed and really want to see a rationale and approach that goes beyond what has been tried and not worked so far. Also, kudos for the open-science approach!
> I have a little problem with finding comprehensive definition of Turing completeness

http://lmgtfy.com/?q=turing+completeness

> in order to decide if certain machine is turing complete does one have to prove that it can also simulate infinite, not halting algorithms?

Yes.
Buffett won't have to pay a billion dollars. As he mentions in one of the articles linked, at the end:

"If you get to the Final Four with a perfect bracket, I may buy you out of your position," Buffett said. "I'll make you an offer you can't refuse."

http://www.latimes.com/business/la-fi-buffett-basketball-bet...
2. +1. I went shopping today and didn't find anything that I truly liked.
3. +1. The deeper I dive into the technology world, the farther I feel from my friends who won't work in this sector and it's becoming harder than ever to find something to talk about that isn't programming-related. Being an empty conversationalist is a surefire way to lose friends fast.
4. Goes with number 3, so I'd pay for this too.

The other ideas sound cool but I haven't ventured into hardware hacking yet ;)
took me five minutes, no login required.
"I am sorry, but our automated verification system cannot process your information, if you wish to continue, we would need to bill you a 25 dollar verification fee to cover additional information gathering."

Its certainly better than their response.
Is there more basic research supporting this interaction (crystallographic or otherwise) between the peptide and T cell? The paper feels like to jumps right into animal models.

"specific points identified by a data-driven analysis of actual individuals’ immune systems" pg1

What is the data in this case?

What is the sequence of the peptide(s) that are incorporated into the PLGA?

Side note: our start up works on helping biotech companies source reagents, supplies and equipment, we should be able to save you about ~15% on the ~475k part of the budget
http://www.whereamidriving.com/ same concept as geoguessr but it's easier I guess because it's multiple choice.