skysight-inc/HackerNews huggingface dataset:
For example, your test says you're sensitive to warfarin and you choose not to have that drug administered in a time when your doctor says it would be the best option.

Then you repeat the test. Your doctor may not have been considering that you may have a warfarin sensitivity, the doctor's family history may be incomplete, etc. etc. This is especially an issue with minority communities, whose medical issues are not as well dealt with by physicians, or medical science in general (minority = fundamentally less statistical strength). It's not a well-known fact, for example that asians tend to have statin sensitivity because of impaired clearance, a lower dose is equally effective in asians (although IIRC while effective in reducing cholesterol, endpoint efficacy of statins in preventing coronary disease is unknown in asians); to my horror I found my father was being prescribed the 'caucasian' dosage of statins, and then a year later, I took the 23andMe test and found that I'm homozygous to a codominant allele that is associated with dramatic increase the risk of myopathy when taking simvastatin. So here my dad is taking an inappropriate dosage of a drug that is likely making him sicker and maybe not even helping prevent coronary disease.

Now, the question you have to ask yourself, is, is it worth it to deny responsible people like myself the power to easily and cheaply obtain these sorts of decisions just to protect people who are going to get hysterical about information, even when there's a second layer of professional expertise that intervenes before any medical action is taken?

look at what this drug did to my grandma

But that is exactly, scientifically valid evidence. I think you are placing an unreasonable reverence on the 'validity' of medical 'facts' or the competence of medical authorities. After all, proper scientists aren't necessarily seeking provable facts but rather, disprovable assertions.
The "first" NPA is 201, and from there the first assigned NXXes are 200, 202 and so on. 201-201 is unavailable. (According to the latest LERG update I have.)
Incompatible by fiat, not by any technical reason. There is no reason the comment system couldn't be expanded into a more extended/threaded system to allow precisely that.

That and the "not a good fit" close reason is the primary thing wrong with SE.
You don't need multiple hard drives to do this. If you have a configurable boot loader (such as grub), you can specify what you want to boot into and skip the menu entirely.
brew install curl --with-ares
5 years is WAY to short. Harry Potter was published in 97, and the film was released in 01. They paid a million dollars for the rights. In your world they would wait a year or two and do it for free. A recent study claimed there were few books on Amazon older than 25 years. So that sounds like a good length.I'm not sure what the length should be, BUT the current length which is longer than the average human life span, is too long.
Using a hidden volume seems like a better idea than hoping they get distracted by "perv" sites.

Not to mention, the legality of porn varies drastically over jurisdictions.
Google will probably abandon it before being content with it only ever being a niche product. I'm not convinced that it (including future iterations) won't become accepted by consumers, though. Everyone is still evaluating a product that is not yet "ready".
I made a site to check if you are affected by this leak: http://www.snapcheck.org . Happy new year, everyone (although on a bad note...)
This is what a sample looks like

"31755501XX","username","Indianapolis"

The XXs hide the last two digits of every number. The list is also massively incomplete.
What Snowden really revealed
The FDA is _not_ trying to prevent this information. It's trying to prevent 23andme from marketing a diagnostic product that doesn't meet diagnostic regulations.

They can't have it both ways. They can market and dump out your DNA data. Or they can meet regs, prove they are clinically accurate, then market it as a diagnosis product.

We'd not like random companies starting up and misleading people and claiming to diagnose but really just flip a coin. That's all the FDA is asking.
Right, because movie ticket prices and dvd prices are going down in the face of free tv and cheap online streaming. Yes today's content has to compete with yesterday's content. But they do already. A new Robocop is coming out. I'm sure it will do just fine, even though you can find the original for cheap or free.
HAPPY NEW YEAR
I think the real lesson is that it is all in how much you put yourself out there!
That's the usual mistake of wearable computing?
I think you are mistaken. The official crowd sourced transcripts for the CCC were more or less complete prior to your efforts. Refer to the timeline for this event's transcript here:
https://subtitles.pads.ccc.de/ep/pad/view/5622/latest

It would be nice if you could contribute back, by making any corrections, as these are the transcripts that are linked to from the CCC's website and probably most people will find.
I have a theory. Last week there was a big story about how Facebook was “dead and buried” because teens didn’t want to be on a service that their parents had moved into. Now, when it comes to security, the parents care a lot more than the kids. Could Snapchat be playing fast and loose with the security of their user data as a way of scaring away the grownups?

This would be a clever ploy but for one damning fact. A large share of Snapchat’s users are minor children. Could anyone, from the CEO of Snapchat to the perpetrators of SnapchatDB really think that risking the broadcasting of the phone numbers of 12-year-old girls and boys is a risk worth taking?

For more, see: http://www.forbes.com/sites/anthonykosner/2014/01/01/4-6-mil...
Hank Greely is not a "genetics prof", he is a bioethicist in Stanford's Law School. He doesn't develop new genetic technologies. This is like calling a film critic a director.

http://www.law.stanford.edu/profile/hank-greely
Interdicting data at borders seems to me as the height of stupidity, considering said data can flow freely across borders anyways, via the internet.

These policies have no legitimate reason to exist, and can perhaps only be explained by a combination of paranoia, ignorance, and incompetence. It would stand to reason that any terrorists or criminals foiled by these methods would tend to be of the exceedingly dumb variety.
On the grand scale yes. For those of us in Manitoba (or presumably, the far north), there's not too much solace in that fact.
I bounced in my third month at a job that I really misjudged. Cut your losses and move on, the market is good enough right now.
That was the one bit of the post that I didn't understand. Google is now shipping Glass to Explorers without them meeting Google employees. Given that, it seems the custom fitting can't be so essential.
I don't know what to use instead of bump anymore. Kind of sucks it never took off. :(
I agree with lack of interaction with MOOCs. I enrolled in three courses on Coursera and dropped out from two of them.

The only one I completed, the instructor was engaging and interactive in the sense, he didn't show just the slides and read, he interacted with the slide. By the time, he finished the video, the slides were all written over in his handwriting.

The one course I dropped because instructor was reading the slides in the videos. I can read slides faster myself, I don't need to watch a lengthy video and listen instructor read the slides.

The second course dropped because instructor wasn't very good at explaining things. He will just show the slides but then ramble on. Though expert in his field, I got the impression that he wasn't a good teacher. Teaching is an art and not necessarily every expert can teach.

The MOOCs need to be engaging, not just the topic wise but also instructor wise.
Is it not odd that Snapchat has 5+ open job listings on their website, none of which include security?
Happy New Year, guys.
I HAVE a theory that a (not so)clever writer for Forbes is plugging his story by planting misguided theories everywhere UPON which I plan to plant my theories on his planted theories on snapchat CEO "rumor" theories.
What questions do you want to ask those nations?
Evans, et al. v. Linden Research, Inc., et al.
futurists at work. some better than others.
Warfarin sensitivity is _precisely_ why 23andMe needs to be regulated; 23andMe has NOT clinically (or analytically) validated any of the claims around the specific SNPs they've identified. All 23andMe does is link to research papers that may suggest that there are gene variants that are linked to warfarin sensitivity; however, these have not been validated to be clinically significant.

In fact, just last month, the New England Journal of Medicine published a landmark study around the pharmacogenomics of warfarin dosing, which found that this very genetic data does NOT affect/improve warfarin dosing (http://www.nih.gov/news/health/nov2013/nhlbi-19.htm, original paper: http://www.nejm.org/doi/full/10.1056/NEJMoa1310669). In light of this, this warfarin sensitivity information that you've obtained from 23andMe is almost certainly a false positive, and if you were on a prescribed warfarin treatment, 23andMe would've likely resulted in a change in your behavior that would be strictly detrimental to your health.
They aren't asking for any secrets just a username. I didn't read the details of the recent issues, is there any reason why a snapchat user name should be guarded?
The MOOCs may have some business challenges with a 90% failure rate, assuming they intend to make money from graduates, but it is no indication of problems with the service from an end-user perspective.

I've signed up for a few courses now with no intent of using them as a school, just as supplemental material to augment my own personal learning venture. I don't really care about the tests or homework prescribed by the service, and I certainly don't care about any kind of certificate of completion.

I don't consider my usage habits a failure though. In each case I came away with what I had hoped to learn when signing up.
They do. When you vote to close a question (and anyone can do that, not just moderators), you have to give a reason. One of the predefined reasons is "belongs on SuperUser stack exchange," and another where you can fill in a reason, such as "belongs on Programmer stack exchange." (Programmer is for code review, style questions, opinion-based stuff, etc.)
Basically, our judges and elected leaders don't believe in the Constitution they are supposed to uphold.
Micropayments go mainstream.
I'll shoot for;

1) We see a 'start-up' bubble form as sites like we funder open the mass market to VC.

2) Bitcoin has some big peaks and dips but ends the year overall on a reasonable up.

3) The US starts to feel inflationary effects from ongoing quantitive easing.
I agree with your sentiment, but I wouldn't call it successful until they've translated the interest into sales to users who are not early adopters.
Visa is not the only party receiving money on the transaction: the processor/merchant bank and issuing bank also both receive cuts which dwarf Visa's.
Ask HN: Big Data Software, What's in it?
Hey guys I keep hearing a lot about "Big Data". I have no idea what it is other than people doing sentiment analysis on Twitter, and Business Analytics Software.

Is this a niche that a freelancer could take up? If so, what are the prerequisite knowledge or credentials you need to earn?

Also what is this big data software about anyways? It seems to me just a fancy charting/graphing software. Is there an open source version of it?

Curious to learn more.
I'm a member, and I didn't even know there was going to be content, outside of the conversation when I signed up. The value I get out of it is a place I can have candid conversations about the business I am building and get actionable feedback from Nathan (and the other smart peeps). Actionable stuff that will definitely increase revenue more than the cost of admission.

It's tough to do this stuff in a vacuum. I've got a hipchat room I hang out in regularly that has the same vibe, and there is value in hanging out with smart & motivated people working towards similar goals.
My ONLY Resolution for the New Year
It has been mentioned to me by recruiters as a positive thing.
Ask HN: How Do You Create An OCR Web Service? - HNY 2014 HN
HNY 2014 HN. Im trying to create an ocr web service with Tesseract OCR, but I dont know how to get started. What should I do? Do I need dedicated hosting service or virtual private service?
Amazing, this is literally the first paragraph in the ruling:

"Since the founding of the republic, the federal government has held broad authority to conduct searches at the border to prevent the entry of dangerous people and goods. In the 21st century, the most dangerous contraband is often contained in laptop computers or other electronic devices, not on paper. This includes terrorist materials and despicable images of child pornography."

Judge Korman is quoting Michael Chertoff, Searches Are Legal, Essential, USA Today, July 16, 2008, at A10.
What's the best tablet upon which to actually read all these papers?
Uber You suck at big time.
"Demand id off the charts! Rates have increased to get more ubers on the road."
How about F_ck you Uber! Stop fucking ripping people off at the last minute.
IMHO, I really think that script should only return whether the phone number is leaked or not, instead of showing the phone number of provided user name.
Great post, it's like you're describing my life - minus that whole "solutions" thing you've got going on :)

Regarding sounds and noises during work, have you tried ambient style music or noise machines in the background, for example:

http://musicforprogramming.net/

I've honestly gotten to the point where I can't sit down and get any work done without it, but I'm sort of paranoid that it might be a distraction and I'm not doing my highest level thinking with it on. I have no evidence to support it, just a concern. It may just be that whole "I get my best ideas while showering/jogging/driving" thing, though.

Also, if you don't mind me asking, would you say you've effectively "cured" your ADD with just the techniques you describe, or are you medicated as well?

Anyway, I'd love to read that blog post if you get the chance.
Seriously? Read the thread. You responded to "Using config tools isn't helpful" with "but mine is python!!1". Nobody cares, it is a completely irrelevant detail. I simply said ruby because the two popular options are both ruby. It still applies to fucking cfengine, it doesn't matter the specific tool.
Check if your Snapchat account is leaked in the SnapchatDB release: https://dazzlepod.com/snapchat/
Because it's Microsoft technologies locked into a Microsoft stack. And before people start chiming in about Mono: Good luck selling that idea in a large bureaucratic enterprise environment. For all the hassle involved you're better off sticking to something that runs on a JVM.
There are a number of existing OCR web services, both free and paid (try Googling "online ocr"). I think some of them use Tesseract. What advantages would your service offer compared to these ?
> We use Java, but languages like Groovy seem good as well.

Because the Groovy project management at VMWare often slip references to "Groovy" into some other query as part of their ongoing promotion efforts, mentioning "but languages like Groovy seem good as well" without any direct relevance to your primary question makes some of us suspicious. I'm mentioning this just in case this is a genuine query.
It's not really overproduction so much as wrongly predicting what future demand would be.

What sells and what people want are highly correlated, which is what capitalism relies on. Yes it's not perfectly correlated and maybe there is a better system, for the most part it works.
This functionality seems like it would be right at home in Google Docs.
I am 100% sure the world will not end again.

Because if it does no one can call me on this prediction.
Maybe I'm missing something here, but why are you throwing yourself at all these technologies? Usually I will only exert effort to learn a new technology when it makes solving a particular problem easier.

The focus here being on the word "problem". That's where I find I get the enthusiasm to learn something or finish that I started, because the problem is interesting or useful.
- Thank you for the response tgflynn and happy new year. I just wanted to understand the architecture of how one is created. Like I want to understand how it works. If somebody points me to a paper or a book, I would be glad to look at it.
What are you searching for? I've literally never seen this on anything on Stack Overflow when coming from Google. I have seen it on some posts while I've been using the site directly, and it's almost always justified, from what I can tell.
webRTC becomes easily usable and almost fully implemented by the end of 2014.
"Then you repeat the test."

What if the test is inherently flawed?

"look at what this drug did to my grandma"

Uh, that is purely anecdotal, n of 1 data, which is not scientifically valid evidence. This is what scientifically valid evidence begins to look like: http://www.nejm.org/doi/full/10.1056/NEJMoa1310669, which suggests the _opposite_ of what 23andMe says about warfarin sensitivity.

The point isn't that we shouldn't have tests for things such as warfarin sensitivity or statin sensitivity; it's simply that we need to have clinically VALIDATED tests for these medical conditions. Otherwise, without a clear understanding of the analytic and clinical validity of these tests, it's possible that many false positives or false negatives arise.

There's a reason why other genetic tests (e.g. Genomic Health's Oncotype DX or Myriad's BRCAnalysis) haven't been pulled by the FDA (in fact, they're not even regulated by the FDA!) - that's because they've gathered sufficient data to support the clinical outcomes and utility claims that they've made. Put more simply, these other molecular diagnostics have actually verified their science. 23andMe has not - that's why they're being regulated.
Since they give a bitcoin address, it's more likely that they want BTC. But yeah, same idea.
The issues arise with the fact that every countries border is inherently leaky anyway: the internet makes sure of that. So, searching your computer and confiscating your device because you're not a fan of some not-even-a-cop going through your stuff will just push those that they want to catch to transferring files somewhere to retrieve when they're in the country.

I'm an Aussie. I have nothing to hide in terms of data on my computer, as far as I know. If I was flying to USA (as an example) tomorrow, I'd wipe my laptop and phone clean, put images on my server, and access them via SSH once I'm through the border... Why the hell do I need to do that?
1. Stock market: up.

2. Economy (U.S. and world): up.

3. Political polarization: up.

4. Stupid-patent lawsuits: up.

5. World violence: down.
You still can't deny that the mechanics of the site are somewhat broken - I have answered questions, had the answers upvoted, only to see the question edited by a mod and changing the fundamental question and adding more specifics, at which point my answer becomes incorrect and is downvoted. This is plainly a stupid mechanic.
<i>... so they are discouraged from acquiring the skills to solve their own problems...</i>

Nobody is discouraging anything from anybody. SO is mainly a resource for programming problems.

For the life of me I can not understand this expectation that SO is a tutoring site. It is not. As a developer resource it is invaluable, and free.
No, good public DNS servers (like Google's) forward your subnet to the resolver to ensure that you get correct responses: https://en.wikipedia.org/wiki/Content_delivery_network#edns-...
There will be an exponential increase in Bitcoin pseudo-intellectuals in the media (and everywhere else, of course).
> "Hank Greely is not a "genetics prof", he is a bioethicist in Stanford's Law School. He doesn't develop new genetic technologies. This is like calling a film critic a director.

http://www.law.stanford.edu/profile/hank-greely "

I'm not sure your assessment is entirely correct.

Here's an excerpt from the same page you linked to:

"Greely is also a professor (by courtesy) of genetics at Stanford School of Medicine."

I don't know how professorships by courtesy work at Stanford.

https://en.wikipedia.org/wiki/Professors_in_the_United_State...

Assuming that the content currently in that section of Wikipedia is correct and is congruent with how things work at Stanford, he is a "genetics prof".

Or we can just take his Stanford bio at face value.

Also, we should consider what the man has to say. Whether or not he "develop[s] new genetic technologies" is irrelevant if his opinions are valid and his facts are correct. If you take issue with the opinions he has or the facts he states, then address those head on.

The man's thoughts are being called upon because he is a domain expert in bioethics (and, as we've just found out, genetics). I think it would be a good bet that this man has a wealth of relevant domain knowledge with respect to state of the art genetics research, gene sequencing technologies, and genomics startups.

Qualification sniping tends to be a poor way of discounting what someone has to say.
If you install wp super cache[1], then you shouldn't have any problems

1. http://wordpress.org/plugins/wp-super-cache/
It hinders international business. How can you negotiate with your cards on the table?
It had never occurred to me that cell phone operators would use area codes. In my small home country, there is basically one 'area code' per cell phone operator. First lesson learnt in 2014! :)
People will start switching to Google+
> It does require that you have trust in a 3rd party DNS provider like OpenDNS ...

The same OpenDNS that hijacks NXDOMAIN responses?
Visualizing the Gender Gap in Computer Science
I just checked this out and it looks horrible. There are no categories. It's just a long list of unrelated questions, like "What's the best app for listening to music?" and "What's the best 2D graphics and physics engine?" It looks completely unusable.
I know people on HN enjoy being hyperbolic, but I certainly wouldn't call a piece of tech journalism art.
You could apparently check via https://dazzlepod.com/snapchat/ if you trust them.
I think he literally meant the CVS given the age of Simon... lol