skysight-inc/HackerNews huggingface dataset:
I'm not a bioinformatician. I'm a biophysicist (BS in Molecular Biology and Biochemistry) who works in computer science. That said, as I have worked closely with most of the world's genome experts (and parried with them on this very issue), I am an authority in this area.

Anyway, I don't mind that you're harsh. It's pretty hard for people to unlearn their years of misunderstanding the genome! There is a lot of misinformation. Basically, you're just insisting on this line of reasoning:
http://selab.janelia.org/people/eddys/blog/?p=683
"ENCODE says What?"

In regards to the ENCODE project's "embarassment", a couple things happened:
1) the press attributed a number of overly aggressive claims to ENCODE. If you read the papers you'll notice they used very hedged statements.
2) ENCODE actually observed some very interesting things. We took their data, and worked on it some more, and we found that a number of their measured transcription tracks actually did represent functional biology. In particular, I can assure you, based on very solid evidence that your estimate that RNA genes make up only 4% of the genome is vastly lower than reality.
I love that "Microsoft has backdoors"...no one credible has said that they have proof of that. They give the US Government early access to vulnerability data...they give those updates to several governments and large corporations early as the result of agreements they have made with big customers. They also let these same entities audit the source code for windows. Look it up. If you have the money and its important to you then, yes, you can audit the windows code base.

"security-conscious people prefer Linux"...That's kind of a sweeping statement. What does security conscious even mean?

To me it sounds like this..."People who talk about security a lot use Linux by and large"..."but some of them are really partial to OpenBSD"..."and lots of Windows security experts really use Windows a lot."

I say that its a shit lifestyle decision because what is it accomplishing? You use this really restricted platform to make sure that people can't track you doing ??? What exactly? Communicating with your team of spy's??? Downloading midget porn??? Why do you think that you can have a single workstation that's good for every security corner case? What in the history of computer security makes you think that is a good idea or even desirable?

Let's take the example of the Iranian dissident trying to avoid the oppressive badies in their weird ass government...what does tails or Linux buy you? You are better off with the "throw away laptop" plan using good opsec and running tor from public places. Don't use it for anything but tor and tweeting your pics of black helmeted assholes. Get a new one as soon as possible. Rotate them with other people. The OS means next to nothing.

People keep conflating tor's uses with every possible InfoSec edge case. The dissident has different needs than a guy trying to make sure that the NSA doesn't catch him posting documents. The whistleblower has different needs than the guy buying drugs.

In all cases applying some critical thinking about what you are trying to do is a bigger exercise than "Winblows is the suxor at securitehz!"

Unix doesn't have a monopoly on security. I'm not saying windows does, but Unix people are kind of crazy about their pet platform.
Fairly sure they've filtered out what might constitute "low importance" searched like terms such as 'weather'. Searches for the weather probably remain relatively stable and don't really tell us anything.
An element of bad advice in this is the recommendation that you leave your cell phone turned on at home during your activities.

If "the feds" considered the possibility that this pattern of Tor activity in various wifi networks around the area all correlate to one person, they could then correlate the set of Tor uses with cell phones that sit motionless during those activities. This will completely out you unless you leave the cell phone in the same location all the time or for extremely large portions of time (a (1 - O(1/n))-sized proportion of your time) where n is the number of Tor sessions you want to perform. That's a bit pessimistic -- you could improve things by scheduling your Tor activity at times you would never be moving your cell phone anyway, and at times other people would consistently never be moving theirs -- a certain hour of the day. For example, suppose you never move your cell phone between 5 and 6 AM -- that's just a pattern in your life, and a pattern in others' lives, and if you scheduled your activity in that hour, you'd leak information much more slowly. But eventually, as more and more active cell phone users have the occasion to use their phone in the wee hours, it'll leak.

You also need to treat your personal internet activity and also perhaps electricity consumption (depending on metering technology) the same way as cell phone activity in this regard. You can't be going out using Tor at 5-6 AM some days and then be home browsing YouTube at 5-6 AM a small-ish proportion of the other days -- they'll nab you with 99.9999999% certainty in no time.

Edit: And you can't even be tired, or energetic, or have any measurable change in social activity before or after the Tor session either, of course.
I remember working for an online retailer several years ago. Their marketing department made it clear that targeting by demographic was outdated and they felt that grouping people by their behavior was a more modern and accurate way of keeping track of people and future habits. Maybe one day media companies will enter the 21st century of metrics when most major media transitions to the internet.
> HS1 also had a promising ROI, but the calculation failed to account for the explosion in cheap flights happening over the same period of time.

I'm pretty sure part of this is due to low/no taxation on aviation fuel, while train fuel is taxed. [1]

1. https://en.wikipedia.org/wiki/Hydrocarbon_oil_duty
Unseen Paul Walker CCTV Footage Before His Death
Unseen Paul Walker CCTV Footage Before His Death.
Yeah, but when googling back then you would do msword.
I can definitely sympathize with your perspective. But that also sounds like a lack of community cohesiveness and unwillingness to improve the area by the local populace.

Where I'm from, we have free schools (anarchist workshops where anyone can attend or present), volunteering workshops, apprenticeships, etc. If you're community has a mafia(s) abusing a local area, you don't send your kids to the biggest one for protection and call it moral. It's just more comfortable. The moral option would be to fight the coercion that your community is suffering from (which seems entrenched sadly).

Also, I don't think public schooling gives a free pass at the potentiality that these students won't join gangs. It's most likely a complex set of reasons that may include that gang being the dominant form of force in the area (a mafia/government w/o the monopoly on force).

Also, I don't believe there is such a thing a no education. Again, just because some people don't have book smarts doesn't mean they aren't smart.
Yes, but the local and remote activity can't be connected. Were somebody to connect and disconnect from Tor in the time surrounding an attack, you could; but you couldn't say that a Tor user is a culprit of an attack that went over the Tor network because they were using the Internet at the time. Perhaps they're just using Facebook or HN as they do many times each day.
This resource .. showcases a number of techniques.

That's kind of the point.. you should not need to have a page to showcase different techniques for something this basic.

I, for one, does not have to deal with this. But as and outsider it seems strange that simple things are so hard. Maybe web developers have gotten so used to dealing with things like this that they don't see how convoluted it is?
Either way, our deployment process to new servers leaves something to be desired.
Nah I've been using it all morning on the website including right now and comes up fine. May have had a glitch like all sites do for a brief second but I certainly wouldn't push to Hacker News until the sites been down for at least 5 minutes or more.
Was learning C the hard way, and checked out authors website. It's cool.
The Hobbit - Ed Sheeran - I See Fire [Cover] by 2KSQUAD
Whoa. The above PDF link is very much worth clicking.

Almost all of those points (except maybe the very last one) are echoed by the OP.

Except that this hand-out is straight-out propaganda and the OP sort of tried to veil that.
The Best Video Games of 2013
Please take this crap back to 4chan /g/ where it belongs.
10 times the U.S. median income isn't "rich enough"?
I think a lot of the differences boil down to once-a-day point-to-point connection of classical or EuroCity trains versus corridors for frequent high-speed trains. Thalys goes every 2 hours, Etoile de Nord once a day.

That's why bullet trains work so well in Japan, you can basically have 2 corridors one on each coast and they will pass through most of the important cities removing the need for direct links.

I do agree with the article in most of the points. I have traveled Amsterdam-Perpignan (the last french city before Barcelona) with Thalys and low-cost night train (and TGV and Thalys on the way back) and I can attest that the night train is indeed quite uncomfortable. At least I could take a gas canister (for hiking) with me...
> Some other journals will outright reject the article because of its "prior publication".

I'm pretty sure that's a decision made by individual journals' editorial boards, not by the publishers.
The Newhaven Marine ghost service in East Sussex is a fascinating example too:

http://www.28dayslater.co.uk/forums/other-sites/70397-newhav...
Converting docx to clean HTML: handling the XML structure mismatch
Ask HN: How to decide which language to use for my life dream?
I want to finally start the web app that I always dreamed of doing. My hope is that it will become my startup and eventually my life mission. When this is what I'm aiming at, I find it very hard deciding what language to use...

I'm pretty determined to start with google app engine (and maybe later move to compute engine) so it leaves me with 4 options really. Here are the pro/cons of using them:

1. Java: my comfort zone. It will take me relatively little time to get going because I have the most experience with this choice. Also, it's a solid choice in terms of performance.

2. PHP: my other comfort zone. It will be the fastest to make a working prototype, so why not really? Since it's app engine, I don't need to worry about scaling it. But then again, I don't like writing PHP...

3. Python: I don't have much experience, and besides I don't really see any advantage for python over php. The plus: if my site fails, it will be good to learn python...

4. Go: it would be really cool... But it's experimental, and I'm not so sure how much time it will take me to take care of basics such as templating and user management...
There's definitely a glass ceiling on developer salaries that tends to cap developer salaries at around 150k. That's problematic for the profession, given how early someone can max out his earnings early in his career. A proficient developer with 5 years development experience can earn 125k fairly easily, which is around 80% of the apparent industry max. So there's not much incentive to improve one's craft beyond the minimum in a salaried track.

Most devs I know who've broken above 150k fall into one of two categories: startup founders or freelancers. That clearly resonates with the "break from the pack" pitch in the article. The founder path is difficult and risky, but fairly understood at this point (no one is surprised if a successful startup pays their founders well).

Conversely, A lot of people are surprised by how much a successful freelancer can earn. There's still an industry misconception that the skilled people must prefer salaried work and that contractors are somehow in a second tier. But 150k is a fairly easy goal to hit for a new freelancer. Someone billing at 125/hr for 1,200 hours will reach that in pre-tax dollars.

That's only assuming a 60% utilization rate (there are around 2,000 total billable hours in a year). Booking a few more hours or slightly increasing the rate lets freelancers dramatically exceed their in-house peers. Most experienced freelancers I know are earning around 2-4x what they earned as a salaried employee.
I get your point, but these are my two options: http://d.pr/i/Mnhm

Top row, slow-speed train; bottom row HST; first column departure time, second column arrival time, third column travel time. If you need to be at a meeting by 8.30am which train would you get? One has a travel time of 4h 16min vs 1h 38min, HST has a higher, marginal, price difference.
Mark All As Read - Therapy for your infobesity.
Please, let's not discuss Java EE.)
Dogecoin, Bitcoin rival used by 4Chan and Reddit
We can say what we will about TED Talks, but it is a hell of a lot better for humanity than Jersey Shore or much of the useless crap on television. Like anything, given enough time, TED will have to fight off self promotion and the recycling of ideas to remain pure and relevant, but I am confident that the fight is worth fighting.

I have a friend who teaches middle school Biology, and his students (in his words) "light up" whenever they watch a great TED talk about the similarities between chickens and dinosaurs or the way a gecko can swim through the air while falling based on something way up it's evolutionary tree. I think science-driven TED talks fill a great purpose in inspiring people that may not (yet) be scientifically minded.

Perhaps it isn't as bad as Bratton believes it is, because I can still show a good TED talk to my non-techy mother or father and blow their minds. My father is a deep thinker, but just doesn't come across deep or novel ideas very often in daily life. He is a football coach, so he just doesn't get a lot of that between dealing with kid problems and trying to win. TED has been wonderful for delivering him a nice, distilled idea to think about.

If nothing else, TED gives the general populace a starting point for the state of high-level research and a chance to think about something other than their mortgage or drama on twitter. And it does so in a manner that can be highly entertaining. It is sadly surprising how many people live a whole day, a whole month or a whole year without being inspired by anything at all. Anything that can inspire the public positively should be protected, refined and celebrated.
And the government remains powerless to close this loophole? They really do seem to be owned by the wealthy and corporate interests. That's sad. The wealthy are little more deserving of their wealth than the poor are deserving of their situation. In fact, if we really do have no free will as science seems to suggest, then the only thing separating the rich from the poor is luck. Then the current inequality is particularly sick.
Artificial intelligence: The machines with alien minds
Well you're right, it's still in private beta so I didn't put much information about it on the homepage.

Office Garden is a platform where employees from the same company get to know each other, have fun and share their interests. We deeply believe that happy employees build more successful businesses.
How to Make and Sell Customized T-Shirts Online
Or the UK's disastrous worst of all worlds system, of which the best run piece is run by the State! [1]

Unless you're willing to build redundant train routes between cities it's not really possible to have competition for train journeys.

[1] http://www.bbc.co.uk/news/uk-politics-22700805
Relevant (Thomas Jefferson's explanation of the nature of inherited wealth): http://www.economist.com/blogs/lexington/2010/10/estate_tax_....
What a shitty user experience. What changed at google? They used to have these rather simple, useful, UIs.
Four days of engagement on Twitter analysed during GOSF 2013
I am on 31.0.1650.63-0ubuntu0.13.04.1~20131204.1, and it was ok here. CPU around 3-4% for most of them. One of them was 8%.
Does the UK have dedicated passenger train tracks?

In the US, most train tracks (in my experience, at least) are used for both freight and passengers (and frequently owned by the freight companies, who shaft the passenger trains to keep the freight running on schedule, but that's another rant). The freight trains could easily be crowding out the night passenger trains.
You and me both --- I remember stumbling across .ARJ files on abandonware sites at the tail-end of the '90s. Even then, they were something of a curio; ZIP was dominant format, and RAR was gathering pace.
Allowing the government to change tax laws and demand retroactive payment is extremely dangerous.
How the pixel scalers in video game emulators work
And easy to rescale, recolor, etc.
I thought it was the boss from NCIS LA
do you have any evidence for this?

Yes. I didn't talk about it until I confirmed it. Someone who knows a lot of people in the YC-sphere also confirmed.

Karma scores of others' posts don't appear here, but they are available (on old posts) using https://www.hnsearch.com/ .

If you look at your placement of an old post (> 3 months) and find yourself at/near the bottom but have the highest-rated comment, then you're on rankban (rankban seems to apply to threads that originated before it was applied).

You can also check for slowban empirically by comparing latency while logged in to what you get in Incognito mode.
That's one that I do think it's cool to be paranoid about. Cellular networks were designed with lawful intercept in mind. Combine that with the work published recently about baseband processors and it looks to me like staying off of 4G networks is a good idea if you are doing something security sensitive.
To strengthen your point: INSEAD's "The World’s Most Innovative Countries: The Global Innovation Index 2013":

1: Switzerland

2: Sweden

3: United Kingdoms

4: Netherlands

5: USA

6: Finland

7: Hong Kong

8: Singapore

9: Denmark

10: Ireland

Source: http://knowledge.insead.edu/innovation/the-worlds-most-innov...

I always take these types of rating with a pinch of salt but it does give an indication.

Edit: I cannot English.
He states that there was more air travel in Europe, and more trips taken in general because of HSR on routes that used to be serviced by air, thus there was no decrease in pollution, instead an increase. This is such a regressive attitude towards transit. Travel makes us all richer, more of it is a good thing (commuting is a different beast).

My understanding is that overnight trains and the other trains that were less expensive were heavily subsidized and unprofitable. My guess is that HSR in Europe is less subsidized and closer to profitable. Many forms of transportation are subsidized (highways for cars, TSA for planes, HSR projects). The subsidies distort choices and encourage inefficient waste by not letting consumers decide with true information as to the costs of their mode choice.
Dictionary.com chooses a 2013 word of the year with gravitas: "privacy"
Doesn't really apply here, the goal is to detect the existence of a (potential) email address in the text, you can poke the SMTP server once you've found something address-looking to ensure that it's an address and not, say, a twitter thing.
Better source for how these actually work instead of the handwaving in the article: http://taxprof.typepad.com/taxprof_blog/2013/09/wal-marts-wa....
I wish Amazon hadn't given up even trying to do RESTful APIs. Nowadays they just shrug and bang it out RPC style (payload is JSON instead of XML, but the song remains the same).

e.g. How do you delete a stream?

Is it a DELETE request for, say, /streams/<stream-id> ?

No, it's a POST to "/" with an entity:

{
"StreamName": "string"
}

Sigh.
...well, unless you have access to cable.
Only the $1 toys left over from the previous movie are action figures, the toys for the new movie are most definitely Barbie...
Apple iPad (first generation) MB293LL/A Tablet (32GB, Wifi)
Junkyard Planet: A look into the multi-billion international trade in trash
Yes, I strongly agree. You'd be better off applying directly.

A machine readable CV just makes it easier for someone to match keywords. Those matches are almost always terrible. I.e., I see you have the word "javascript" on your resume, perhaps you'd like this "java" job post.
Realtime US Map of Totally Bored Students
Click link in the right sidebar to view the map.
Seconding sanswork. The ability to tax retroactively is the ability to jail anyone and confiscate everything they have for any or no reason. But I guess ignorance of the future is no excuse?
The easiest path to decentralization is to either:

1 Give every user a publicly reachable IP address at their home or business, or

2 Give every user an account with some remote organization that with a publicly reachable IP address, where the user can be listed in some sort of IP address directory. (Some users now use "dynamic DNS" for this purpose.)

I say 1 is better than 2.

The first big hurdle in the problem of decentralization is reachability; 30 years later, users of today's internet are not "directly" connected for two way communication. By getting users past this initial hurdle of end-to-end connectivity, it opens up the problem of centralization for all developers to solve. The user can pick and choose her software to make direct connections to other users, or she can choose none of it.

The www is a given. Every web developer assumes users can access the www. Direct connections to other users should also be a given. And every developer should be able to assume that users can connect to each other.

It's clear that users want direct connections to each other. They want to communicate. The success of store and forward solutions like email over several decades is proof. What's not clear is that they want (or need) a middleman to broker their connections.
> No-one builds a railway to run night trains, but once you have the route built for the daytime services, running an extra train at night on an otherwise-empty track must be very low cost business.

The operators find them unprofitable (at least in the UK). AIUI they can be very disruptive to track maintenance (particularly given modern safety regulations[1]); they also require paying staff, keeping stations open during the night, leasing nonstandard carriages that can't be used for anything during the day (which in turn means either dedicated locomotives or careful scheduling and shunting, something that modern railways try to eliminate as much as possible). Certainly the sleeper train to Scotland is heavily subsidized and I believe the one to Cornwall is as well (less confident of that though). With Eurostar, AIUI the government even bought and fitted out sleeping carriages in the early days of the channel tunnel, before they turned the whole thing over to a private company to operate - which then concluded that night services would be uneconomic, and sold the carriages off cheaply to Canada.

The ghost trains you link to are more about a legal obligation; even if they cost the relevant companies a lot of money to run, they don't have any alternative. (And honestly an off-peak daytime service, when the trains are already out and the staff already on shift, isn't really comparable).

[1] Which are not unreasonable IMO - people have been killed by e.g. a train on the track next to the one they were working on.
Assuming that's not how human minds originally evolved in the first place. Its a big world out there, if there's a tasty niche its probably already filled.
Chinese collider expands particle zoo
GNU gzip is surprisingly well commented (as in, I was surprised to find some multi paragraphed comments at all!)

For understanding the algorithm, surely it's better to look at sources like this document rather than a code interpretation of it?