skysight-inc/HackerNews huggingface dataset:
Genetic tests are classified as medical devices, a category requiring a strict approval process with the FDA [1]. The other "bullshit" products [2] you mentioned do not fall in this category. The debate should start at whether 23andme tests should be classified as medical devices instead of claiming malicious targeting by lawsuits and the FDA.

[1]http://www.nbcnews.com/id/37638671/#.UpWQiNIwrIy

[2]Acupuncture seems to help my migraines. I'm comfortable with not having a rational explanation for why it works.
It's funny, for all the work that goes into some things simpler is so often better. I've had a lot of value out of the content antirez has posted on his blog - all along it was just a block of unformatted text.
The essence is that Apple's locked-down version of the user experience is very poor, but that the app developer is the one left with the blame.
hey that's like the weird website i made for my internets a few years ago! http://www.lzimm.com
It makes logical sense, so it must be true!
http://i.imgur.com/ip6zwes.png

On Linux you can choose different behavior; so it's apparently software. At least, on machines I've worked on. Depending on that dropdown, I can plug in headphones and the built-in speakers will continue to output.
Same here... I had to look up what RJ47 was. Probably just a typo.
Possibly but that does nothing to assuage the concern that entries were only seriously considered if you had an inside connect at Salesforce, which is what it looks like when the winners have close ties to the contest holders and many entrants complain that their analytics show their app was never used.
Fair enough. Could you perhaps link to some of the reviews that you found?
No need, because you can gzip compress, which will make even better savings than that (because it can also compress and save space taken by tags etc, not just class names).
If you live in a filter bubble, it is your fault. Google isn't the enemy.

When you believe something and want to check the validity of said statement (already something almost no one does), your Google searches should not be guilty of confirmation bias. For example - you think test driven development is a pile of crap. If you search for "TDD is stupid," then that is not Google's fault. That is your fault for not understanding remedial philosophy/logic.
A bit of interesting trivia - I knew I recognized the COO Philip Walton who has his picture near the bottom of the page. He's been on TV and in the news because his wife is a survivor of the Westgate mall massacre. Small world...

http://hawaiitribune-herald.com/sections/news/world/kenyan-t...
Well said! My startup, Beeminder, actually implements auto-canceling subscriptions. I've been trying to convince other startups to do the same: http://blog.beeminder.com/autocancel

Previous Hacker News discussion here: https://news.ycombinator.com/item?id=5664998
I don't think we have enough comments complaining about its web design. We probably need a few hundred more!

I get that moaning about its design lets you feel smart by participating in the discussion without actually contributing anything meaningful, but at least just upvote a single person for it instead of posting the same damn comment over and over again.

----

I like that it seems as open and adaptable as they could possibly make it while also keeping it simple. It would be interesting to see just how rugged it is. I'd also like to see how this could be used in an environment that requires a little less "ruggedness", like a coffee shop or a community board room.
Even if you can manage to implement a system where everyone trusts the deal, you still have the problem of collusion between players.

You can avoid collusion by only playing heads up (2 players), but then you have the problem that there is very good AI for heads up.

In short, it's probably not possible to completely eliminate it.
Bezos pointed out something rather salient in the interview:

Currently Amazon is a disruptor. They are doing things that no other online retailer is doing, and they're doing it better, because they chose to shoulder that risk. But merely because Amazon is doing better now doesn't mean that someone else won't come along and disrupt Amazon and kill them.

In fact, Bezos fully expects that to happen someday, and almost seems to welcome it. I think because it means progress.
Hardwired differences in male and female brains may explain aptitude gaps
>fairly puzzling

Apple and telecom? I think the picture is pretty clear.
No, AKA "the socratic method."
The right to sue isn't bad.

It's still up to the court/judge/jury whether or not the other person has a valid argument.
That's all true, but the "disclaimers" on homeopathic pills and bogus diets are so weak compared to overwhelming testimonials that the "disclaimer" amounts to ass covering boilerplate that makes no practical difference in terms of people getting fooled.

Maybe 23andme screwed up by not running text in 8 point font and a fast talking muted announcer saying "information may not be accurate or useful...blah blah...", but this seems to be a huge inversion of priority compared to potential harm.

People have been poisoned by "supplements" containing lead or arsenic, or killed by ginseng/ginkoba/caffeine overdoses in others. Millions more are ripped off by diets with utterly outrageous claims and faked testimonials.
I have not quit my job...yet.

I have been tasked with creating an android app for our latest product line up. I asked to not do it, and it's not like I was hired to do mobile (having never developed for mobile before). I was asked to do it because I have a history of ramping up on new platforms quite quickly, so my CTO dragooned me into it. I'm 2.5 years into this job and I hate my commute and don't care at all about this stupid app. It's all I can do to stay motivated.

The way I'm staying motivated is by giving myself permission to leave once the app is done, so I'm knocking it out as fast as I can so that I can run screaming from the building.

I would like to work in non-profit to see what it is like. I have a suspicion that motivation and freedom might (or should) come at a lower cost. I'm not a dough-eyed idealist, I understand the business decisions will trump my personal preferences quite often, but if that's the case I'd actually like to believe in what I'm doing. I consider myself a team player, but I also want to give a shit.

What's your story?
Yeah but they still get the _idea_ for free. Code is cheap.
I personally don't think the government has a right to tell me I can't read my DNA. A medical device that tells me the chemical content of my spit can't physically harm me.
> Through 23andme, I found a moderate genetic disorder that I have which prompted me to make certain lifestyle changes that will very likely stop me from having emphysema relatively early in life. Because I had the particular disorder, I passed this information on to my sister and through testing not through 23andme, she discovered she has it as well.

How do you actually know you have the genetic disorder? Could it possibly be a bug in 23andme? [1]

[1] http://qz.com/151311/why-23andme-might-have-the-fda-worried-...
There was a time when DPI and PPI were effectively the same thing (72 per inch). As monitors became more dense (but before retina) this approached 96 and then 130.

If you've got a Linux workstation handy, try manually setting your x86 DPI to match your monitor's specs. Everything will look giant because most apps are written assuming DPI is an arbitrary constant (75 or 96), but most people use monitors that are more dense than that.

When you set your DPI to be its actual value, you'll realize that people have become accustomed to screens being more dense over time, but there was certainly a time when DPIs in the 70s were considered par for the course. In fact, many older people prefer less dense pixels because it's easier for them to see bigger things.
Master-cluster: A module to facilitate using node cluster and domain modules.
That statistic is somewhat misleading. Or, at least, not very meaningful. A more meaningful statistic would acknowledge the different "weights" that certain languages carry (i.e., "how many people use it").
Salesforce Style Guide
You're looking at it the wrong way around - why would a restaurant use that? Do they really want you to be able to access the menu of the restaurant next door?
Fedex and UPS suffer from the innovator's dilemma which will make it hard for them to build the best drone service with the right business model because it means they'll lose money, sunk investments and jobs relative to their old business model.

Anyway, this is probably a field rich with patents and amazon with their acquisition of kiva robotics and their attraction as an employer in this field with this PR, will grab quite a few patents and make it quite hard for other companies to compete.
I was about to say the same thing -- glad to see I'm not the only one who recognizes the real reason why there will be no more competition in this space.
One key thing left out in the hardware specs: how much does it weigh? Does it weigh just as much as its name says?

If I am to lug this around it better be as light as possible.
and, often, ORMs go even further in making bad choices the path of least resistance

And when the ORM alone isn't enough to make an application performant? "Fuck these RDBMS, lets get a real database engine in here!"
The real topic is overreaching FDA with inverted priorities and ambulance chasers.

If the government is to regulate, and it has limited resources, it should regulate those that do the greatest harm.
I'm ignoring too. I was looking for a way to get value out of it but have not found. I'm surprise by the lack of creativity of those ones.
locker room != restaurant.
crime != policy

And I'm not saying video. I'm saying banning because capability of taking video. Cell phones are not banned in locker rooms. Recording with them is.
To this point:

> Most of 23andme's customers were early adopters, especially when the price was much higher, I find it hard to believe the plantiffs in this lawsuit were duped into thinking it does anything more than claimed.

You've actually hit on exactly why the FDA decided to initiate enforcement action on 23andMe. The FDA has always taken the position that what 23andMe was doing was not necessarily permitted, but used regulatory discretion and did not stop them. The rationale was that since 23andMe did not do mass-marketing, the people using the tests were seeking 23andMe out and were educated on what the tests were.

23andMe has made some stupid choices, like not engaging with the FDA over the course of a number of months on this issue, and this was all brought to a head when 23andMe broke the implicit agreement with the FDA and started mass-marketing.

And on this point:

> that doesn't really promise anymore than a statistical printout of your DNA.

Their profiles now have a "key health recommendations" section if you've taken the test (I have), which, again, is a big no-no, and part of the reason that the FDA decided to initiate enforcement.
How do you actually know you have the genetic disorder? Could it possibly be a bug in 23andme?

Actually, the part of my original comment that you quoted shows that is extremely unlikely. Here it is:

I passed this information on to my sister and through testing not through 23andme, she discovered she has it as well.

Specifically, my sister got tested through a blood test from the foundation for this genetic disorder and verified that she has the same genetic disorder I do. Is it possible that 23andme wrongly stated I have a genetic disorder and that coincidentally my sister has it but I don't? For some genetic disorders, perhaps. But with mine, there's exactly 0% chance. 23andme was correct in my case.
That's messed up, that there are stricter standards for

a) (correctly) reporting the current state of research regarding a patient's genetic markers, than for

b) someone to sell an unproven, expensive technique as a remedy as long as they include some disclaimers.
What's wrong with the existing PC OSes? =).

In the free/open space, we already have fifty billion variants - Linux, the various BSDs (FreeBSD, NetBSD, OpenBSD), GNU Hurd, ReactOS, OpenSolaris, Haiku etc.)...

Do you want more? I mean, I get the whole diversity thing, but after a while, I suspect you get diminishing returns...
If the comments are outsourced then why have a backend at all? Just pop all of the posts into an S3 bucket and update the index when creating a new one. No server needed.
New York Lawsuit Seeks 'Legal Personhood' For Chimpanzees
The government isn't saying you don't have a right to read your DNA, it's claiming this particular device is fraudulent and its ads are deceptive.
So patent trolling is not bad as long as trolls win? Good to know.
Who puts out a new item like that without instructions?
If anything, I'd say that Southwest has much more in common with Rand's heroes than Ryanair. To stretch this ridiculous comparison further:

Like Southwest, Roark didn't nickel and dime his clients. Rather, he simply pursued his own architectural ideals: simplicity, elegance, form following function -- to hell with everyone else. You can see the same in Southwest. They eliminated the artificial seating charts, standardized the ticket prices, and allowed bags to be checked for free. They simplified logistics, improved the experience, and didn't think twice about bewildering passengers.
That's a really good point - also, Dublin-London is a bit of an outlier because it's from one major airport to another reasonably easy to access airport (Stansted, a 47 minute £12 train ride from Liverpool St.)

If I had to fly from Glasgow to Paris I'd be heading to airports over an hour out of the city on each end of the trip and it would be brutal. As it is, getting to Dublin airport is kind of a pain; I usually take bus 16 or 41 but I wish they would just put a DublinBikes station at the airport.
>The problem with gas and this style of aircraft is that they would need to be hybrids, or else you would have a lot of weight dedicated to very complex transmissions.

I believe that on airplanes they often solve the problem of internal combustion engines being much more efficient in a narrow RPM band (with the constraint that transmissions tend to be heavy) by using a constant speed propeller[1] that spins at the optimal speed of the engine, and adjusts the blade pitch to adjust the speed of the vehicle.

I don't know if it would work on a VTOL type vehicle or not, but we've been using internal combustion engines for a while, and have reasonable work-arounds for many of their shortcomings.

[1]http://en.wikipedia.org/wiki/Constant_speed_propeller
Pythonium: Python 3 to JavaScript translator
The article is kinda paradoxal...

> the iphone changed the game

> no device can enter the market without carrier help.

The iphone was successful exactly because it sold to rich people before, with no carrier help. in fact, in the beginning the carriers would throw anything at you to move you from an iphone. In fact, the reason you have to pay a "smarphone fee" until recently was because AT&T greedily charged a mandatory $30 extra for "iphone data" if you ever wanted a subsided iphone.
A few sushi restaurants in Tokyo have been doing this for a while now. You choose what you want on a touchscreen (usually an Android tablet, often running the same software across different restaurants) and a few minutes later your order gets sent to you on a rail separate from the normal conveyor belt.

After you pick it up you press a red button on the tray in which your plates arrived and it goes back home.

The nice thing about this is that it allows kaitenzushi restaurants to have table seating with the same wait as counter seating.
Dogfooding his own project I would assume.
This may vary by airline, but I believe stewards are generally paid an appallingly low rate (well under minimum wage) for any hours that aren't actually flight hours.
Cryptsy: Trade over 60 different types of cryptocurrencies
It's not about writing code that relies on these things. It's about knowing what things really do when most people think they do something else.
But less trust than the currently used alternatives. In a 2 out of 3 transaction you have to trust the arbitrator is not colluding with the other person, but you don't have to worry about him taking the money for himself.
Damn... After I think I've got all the knobs set "just right", I'll always reboot just to see what happens.

This usually catches various common problems not quite as serious as this one... daemon doesn't start, kernel panics, more updates required after boot, etc.

The last time I had something like this happen, needing to restore from a weekly backup, Google or Archive.org had already cached everything new and I was able to recover it all without much hassle.
Seriously, this hipster "design" insanity has to stop. It's hurting your business.

A pretty picture of your product is not design, it's a dream of a first year art school student who doesn't understand business, who doesn't understand how to send the message and how to describe the product.
I've had some good experiences with GoDaddy support recently, including one case where a client's site had a custom php-mailer whose messages seemed to be disappearing into a black hole somewhere, and the front line support tech (not even tier 2) read the PHP code in question, determined it was fine, checked the mail queue, and verified there was a problem on their end.

"Surprised" doesn't quite capture my response to that.

I'm still not a fan of GoDaddy the company, GoDaddy the infrastructure, or GoDaddy the horrifyingly bad control panel "interface", but GoDaddy support could teach Google a lot.
Wouldn't inlining the js mean that it's downloaded for every page request instead of being downloaded once and cached?
that only ever affects the bottom of the market.

where i came from, you'd actually made fun of people that had the phone from the carrier billboard.
Lots of websites make key health recommendations based on family history/ancestry, and behavioral questionnaires. Why are they exempted?

Why can someone make a website that asks you about age, drinking, smoking, activity levels, height, weight, etc and then make health recommendations, but if it comes from sampling DNA instead of verbal questioning of potential heredity traits, it's magically different and bad?
And a blog requires a Redis back-end because?

I've hosted my blog on S3 & CloudFront for a while now without issue. Comments are hosted by Disqus, and the static files are generated using Pelican.

Seriously, unless you're using your blog as a massive CMS, why not use static files?
Would this allow a satellite internet add-on if you find yourself going somewhere seriously remote? If so, does such a satellite internet peripheral already exist?
CrossFit: The Good, Bad, and the Ugly
We parsed a lot of the data from App reviews (about 100 million) in different countries. Languages used are predominantly skewered toward english or other european languages. For example, in Israel, 51% of all reviews are in english while only 46% are in Hebrew.

Writeup on major countries: http://blog.sensortower.com/blog/2013/11/27/what-apple-app-s...
So poor people should try getting rich because there is a chance everyone will get poor? (Meanwhile the rich consume as usual.) Don't you see how fucked up that stance is?
Southwest is not really a "budget" carrier anymore.

They may have started out that way in the 70s when the level of service on traditional mainline carriers was much higher than it is now, but since then, most other carriers have adopted elements of Southwest's business model. Some of the mainline carriers have even gone further (see no free bags, charging for assigned seats, etc).

Especially now that Southwest flies to major airports (DFW, BOS, ATL, the NYC area airports, SFO, etc), I would classify them pretty much the same as the rest of the majors. The only thing they don't do that the majors do is allow their fares to appear on aggregator sites. That, and the free-for-all seating (which I can't stand, but that's a different complaint).

In fact, unless you book far in advance or catch a fare sale, Southwest is amazingly expensive to fly on. A couple of months ago I had to travel on short notice (death in the family, only 3 days until the funeral). An airfare on Southwest from Nashville to Boston was a 56% above the competing mainline carriers. And if I flew into Providence, which would have been more convenient, it was an astounding ~75% higher than Delta or US Airways.
What shuffling algorithm do you use?

Here's a description of a very solid one: http://www.briggsoft.com/docs/pmavens/Technical_Shuffling.ht...

Here's an example of what can happen if you do it wrong: http://www.cigital.com/papers/download/developer_gambling.ph...
HealthPocket, like HealthSherpa, offers a workaround for Healthcare.gov mess
|I don't think we have enough comments complaining about its web design

I think the issue here, and we definitely saw this a ton with that Sailfish OS or whatever phone recently (probably fitting that I can't remember what it's called) is with some of these product launches, there is an extremely vague title submitted to HN that gets voted up to the top. There is something alluring about seeing that the community has voted this new thing, whatever it is, as the most important item of the moment. And when we get to the website, we are disappointed and/or annoyed when we can't figure out what exactly this thing is or why it was voted to the top of HN. So we talk about our experience on the website itself, as if it had been presented as a design critique.
Maybe because the US funds the weapons that kill them like dogs and deer in the streets and in their homes. Just maybe.
Create a filter to send Picasa mail to a folder you then proceed to ignore.
The lies behind this transatlantic trade deal
Wouldn't sending out any lifeforms from Earth to other planets contaminate, for lack of a better word, the environment there? There could be a lot about these places that we don't know yet.
I wrote a longer reply that you may not have read yet (just posted a few minutes ago). I thought the spirit of the question was more to an irregular immune system and not just specifically a weakened one. Allergies are not indicative of a weakened immune system - whether or not 'compromised' is a term worth using for a system that is irregular is probably not a debate worth having, but the individual clearly is compromised.

Agreed that it's not nitpicking to know why vaccines cause a potential danger - overactive or underactive immune systems obviously react (or don't) in different ways, but I understood the nature of the question to be much less specific (are vaccines contraindicated in the sick, instead of are vaccines contraindicated in this specific group of sick people).

What you point out is not an obscure detail, but if the spirit of the conversation were how I had interpreted it, the detail wouldn't be relevant. I focused more on the vaccine being recommended to sick people and not people sick with x.
Are you looking at doing something like Ventrilo's PTT (Push-To-Talk) -- hotkey-based transmitting like 2-way radios?
Happtique certified mobile health apps store your UN/PW/Pin/PHI in plain text
this is the blog of the guy that wrote Redis.
Security Systems of the Rich and Famous
that is my main fear.

Today even the most open android phone have the bootloader and radio firmwares closed because of patents.

no matter how good ubuntu will be, it will end up only being offered ancient radios by qualcomm and the likes. and they won't be able to work around since the standard is patented by dozen different people. You'd probably will only have single band phones in the begging. or maybe i just worry too much...
I was thinking about getting the Karma actually. The 14 dollars for 1GB is cheaper than tethering.
I don't understand why you would want HDMI 2. DisplayPort is pretty much better in every single way.