skysight-inc/HackerNews huggingface dataset:
I think one can make a million hypothetical arguments against the testing. But, I just don't see people taking the test at face value and making major life decisions without further follow-up. I think most reasonable people would consider it a screen.

If the testing was wildly inaccurate, then that's another issue. It almost becomes more an FTC consumer protection-type matter at that point. But, there is no indication that this is the problem. They go on to state that their testing is done in CLIA-certified laboratories:

https://www.23andme.com/howitworks/ (near bottom of page)
http://www.cms.gov/Regulations-and-Guidance/Legislation/CLIA...

BTW, I'm not really defending the service, per se. In fact, I have issues with it that are more along the privacy lines. I just don't see where there's any proof that it has an outsized chance of ruining lives any more than, say, in-home HIV testing.
An invasion of all world forces include Canada. And you could try to transfer troops trough the north pole (it will be a logistical nighmare) And in Canada you have the energy sources for the war effort.

I think that this "military expert" is gravely underestimating the resourcefulness and inventiveness of humanity when it comes to killing each other.

You could also do your best to blow up the Gulf Of Mexico oil infrastructure and US is on 3 month lease of life (or an year if it is stretched for military use only) which could make them move on the offence. Add some propaganda to create domestic problems at home ...

If you remove the nukes it comes down to oil and humans. US is outmatched in both.
And how long after I take the time to import all of my loyalty cards into this system before Google decides to go a different direction and shuts this down?

Sigh...
Our DDOS recovery plan is to just shut everything off and admit defeat. Brilliant.
How to use Google Analytics as a Recommendation Engine?
Hi, yid. UPS protects against multiple simultaneous system crashes. Single system crash gets failed over, no problem. If both UPS systems detect their upstream PDU's as being out, then the InfiniSQL management protocol will initiate graceful shutdown, including persisting to disk. For write() issues, at least intially, I think that stuff in commodity hardware (such as ECC memory) is sufficient protection in most cases. Attaching a high end storage array, or using ZFS, also protects against low level disk problems. I don't see those problems as needing to be solved for a 1.0 relase, but am very much open to contributions that address those issues any time you want!

The fundamental insight about not needing transaction logs is pretty simple actually: if the power is guaranteed to either stay on, or to allow the system to quiesce gracefully, then the cluster will not suddenly crash. That's the motivator for transaction logs--to make sure that the data will still be there if the system suddenly crashes. Get rid of the need for transaction logs, get rid of the transaction logs.

Regarding consensus, I expect that there will be a quorum protocol in use amongst an odd number greater than 2 of manager processes, each with redundant network and power. But the specific protocol I haven't ironed out. If there's something I can grab off the shelf then it may be preferable to implementing from scratch, but I haven't gotten there yet.

This stuff hasn't been implemented yet, but the core around which it can be implemented, has been.

Do I sense a volunteer? ;-)
What the average user thinks about Linux
Oh, I've no illusion that it's easy. It's just one of the few possible "building something for bitcoin miners" developments that is likely (if it happens) to have significant positive benefits (other than through bitcoin) long term. I wish anyone attempting it substantial luck, as well!
> Every single piece of information on 23andme is accompanied by [a] confidence estimate, and most of it is very low confidence.

Another customer here, and this has also been my experience. I have found their results presentation very responsible and low-key. A lot of these correlations are quite weak, and they're very clear about that.

I wonder if the real dispute here is over whether giving confidence estimates is good enough. Perhaps the FDA thinks that the general public are not well enough trained to interpret them.
Great post and I'm totally agree. Once I got a idea, i do it quick and release it earlier, that's cool than just talking. but i usually lost after I release my first version of my project. I don't know how to promote my product, how to raise traffic and how to let people know my product, that makes me really confuse. I think marketing knowledge is also very important for engineer
Sure, nobody deserves to be taken advantage of, rich or poor. But being taken advantage of is a fact of life. It's pervasive in nature. Moreover, it comes with the territory of inheriting wealth.

It seems odd to me to feel bad for someone who had this problem only because she inherited a bunch of wealth she didn't earn. That's not a question of what she "deserves" but rather who "deserves" our sympathies.
For 3: email forwarding + vacation autoresponse help a lot. You get the messages anyway and whoever emails you gets an automatic reply with your new contact information.
The relevant part starts at 8:20.
> So one guy got some bad indicators that proved to be nothing, who cares?

The people who get incorrect results and who then go and do things based on those results - don't have children or do have surgery or etc.

> Quick, stop doing CT scans

You have a CT scan when there's something wrong and you need a diagnosis. Pre-emptive CT scans are not recommended. That's because there's so much stuff that might show up but which is totally harmless. But, because you've seen it now you need to do something about it, and those tests carry some risk. Just the stress of "shadows" is considerable. See, for example, CT scans that show rubella scarring, which is something the patient would not know about until they get the CT scan.
I really don't like the idea of sports like football after that where people pile on concussions. I just don't see how it could be a thing that couldn't be detrimental.

There's a high school that I pass on the way to the dog park, and on Mondays the team is always outside for football practice. Watching them damage themselves right in front of the school breaks my heart. I am convinced that American Football is going go suffer the same drop in popularity as boxing within the next decade.
Is someone with a false negative from 23andme in a worse position than someone who hasn't had a genetic test?
Re: pure magic: perhaps the SAN is willing to talk to whoever sends it packets, and/or to be administered by whoever can enter admin:admin into a poorly-secured web interface as soon as it loses the appropriate connection/reboots due to overload/..?

I agree with my sibling comment that this seems an odd way to install a SAN.
Or you pick a partner with DNA to minimize chance of inheritable genetic diseases by offspring.
Just want to chime in and say that I've used this while building multiple sites in the past, and I really dig it. At the time it was my first dive into anything rack-like, so I didn't have much to compare it to, but now that I'm in Ruby-land, I can say that it's a job well done.
I really like these posts from people actually doing remote work. I think with more stories like this we can counteract this idea that remote work can't work. Obviously, we need examples from many different sized organizations.
That seems infinitely better than catastrophic loss of customer funds.
Making scalability painless: Demystify the back-end & combine testing/monitoring
Not always pissed.

Sometimes. just. emphatic.
I'm going to offer an alternate suggestion. If you want to learn how to program compilers, or any other new domain for that matter, start in a language you're already comfortable with. That way, you're only learning one new thing at a time.
There's no difference as if you shut your site down everytime someone DDoS then you'll have no customers anyway.
SpaceX Falcon aims for telecoms market with SES-8 launch
So, you're saying that none the of innovation or money funneled into finding Bitcoins will lead to zero reusable innovation? It will not create more profitable companies that produce ASICs? It won't possibly lead to even lower power ASICs? Better manufacturing techniques?

Doesn't the fact that money is being redistributed to technology companies good for technology, by definition?
Presumably because they're spending time on their actual technology rather than fiddling in Photoshop and keeping up with patching the latest Node.js vulnerabilities on a web-appified version?
I never said two wrongs made a right, nor did I say anything about wealth inequality. Indeed, I went to great lengths to avoid making any "right" and "wrong" judgments at all, simply because I find those awfully boring.

My problem was with the tone of the article. Why feel bad for someone who suffers a natural consequence of inherited wealth?
How to Commandeer a Starship: Fine-Grained Permissions with Stormpath
All those sliders and flyins but the hell out of me. I find them as obnoxious or more so than slides.

(fwiw)
This applies to traditional work too, doesn't it? Sure, a brick layer can measure based upon how many bricks but I don't think it makes sense for programmers to measure a "good day's work" in terms of just time spent coding ... I think it is more about progress. Even if you didn't write any code, did you make some conceptual breakthroughs that will lead to better coding tomorrow?
MDF Python Data Flow Toolkit
How losing information can benefit quantum computing
For companies who are considering going remote have you considered the "global" problems you may have (e.g. payroll, local compliance laws - holidays etc.) ?

Do you have solutions for them?

There's a cost for most businesses to being in different countries. Typically, for larger businesses, finance and HR pick up most of the slack here. Having 17 employees potentially in 17 different companies feels like it might be a bit of a logistical burden. Any counter experiences?
If you want to do something around ecommerce, this could be the big startup IDEA that you do!

http://blog.uberstarter.com/planz-2-instagram-ecommerce/
> The FDA are simply enforcing the medical industry monopoly on diagnosis.

23andMe could sell their product as not being diagnostic. Since 23andme chose to sell their product as being diagnostic it's fair enough that their held to the same level of regulation as everyone else in the sector.
Handwritten digits and Iris databases are the most frequently used ones in most books and tutorials I've read.
I think it's good idea because you can compare between different teachers/techniques that base their content on the same core data.
Reading between the lines you are suggesting that this vector of attack had to come internally from BIPS? Given how much bitcoin price soared it is not unreasonable to question whether one of the engineers there had his price named.
The launch is scheduled to be broadcast at 5:00 PM EST.

http://www.spacex.com/webcast/
Or conversely, once the caregiver is in the will the patient is toast.
@fleitz A million dollars difference, seems to me.
Let's just hope this doesn't get renamed to "Revisions" by some misanthropic, overzealous HN invisimod.
Exactly

The point, really, is that eugenics itself is not necessarily evil until and unless you attempt to control the reproductive rights of others by your own eugenic criteria.
Would you care to provide your interpretation of "Now imagine that your genetic testing service has a data breach and suddenly you have immense difficulty getting hired, getting credit, or getting a table in a restaurant."
Yeah I was probably being a little snarky there. I'm sure that the vast majority of doctors, even in profit-making systems, are just trying to do the right thing. But there's no reason the less scrupulous ones couldn't be doing it for both reasons ;)
I don't understand how that could be worth it for Google, though. Amex processing charges are higher than Mastercard (AFAIK) so if I pair my Amex to my Google Wallet card, aren't they going to end up paying processing charges the store would normally pay?
I love living in a science fiction cyberpunk novel
I found it a little out of place to mention the subject's size in this article.

He's going to beat the copyright industry with his brains, not his girth.
Enterprise perspective of what Google Glass developers should be creating
As a former player, and customer service representative of the game, i can say confidently that the reason Ryzom failed had nothing to do with bad luck, and everything with bad decisions and incompetence.

They had no qualms about changing large parts of the game. The prime example being that they changed the experience distribution in the game such that where it was first that any large group of players could play together and cooperate, after beta it was changed such that only squad-sized groups could cooperate and squads being in the same area only meant difficulties, since experience could not be shared anymore.

On the technical side they had a lot of terrible code as a result of much of their 50 man staff being students doing an internship for free there. They also had a very bad attitude towards volunteer support staff, where, for example, an issue on the web site would be reported, the dev in question would say nothing, and when asked five minutes later would say "What problem, i see none?" after obviously having fixed it.

Lastly, they also had a very bad attitude to players. The game had guilds and an ingame browser (kind of hidden, since it was the backend for 90% of the game UI), so some enterprising players had figured out how to use that to provide guild forums. The result being legal threats.

As much as i love the game still to this day, and still hold on fondly to the screenshots and memories i collected in its wonderful world, it wasn't luck that killed it. It was Nevrax' incompetence and shortsightedness.
What would be wrong with offering a product that sequences your DNA, then highlights the most interesting bits with links to external sources? A customer would still get the benefit of knowing high-risk/important things to check out, and 23AM would be clear. The website could wrap it up to make it a smooth experience.
Can I beat Shopify with this product pitch?
You mean in addition to being technically incompetent the team was also too stupid to buy insurance?
Small-Town Police Driving Around in Eighteen-Ton Armored Vehicles From Iraq
As opposed to options and products provided by other companies, that are guaranteed to be around forever and ever.
I don't know about others, but I don't need a stinking apology. I need to stay away from LG as a company per se, and its a great timing because this thanksgiving I'm getting 80" TV, and trust me, it WILL NOT be from LG.

Hope LG made up the $ difference by selling customers' info, or whatever else they do/did/continue doing with this data.
There's really nothing new at all here technologically. ASICs are old hat.
I could opt out, but I really do want to know my ancestry information. My objection is them sharing my information before I even get a chance to look at it. It's like if you had a baby, but the nurse and doctor published your baby's photo on Facebook before handing you your baby. Why should anyone get to see my information before I do? And then they get to contact me before I even know why they're contacting me? That's bizarre to me.

At this point, I have my information and now that I have it, I'm okay with sharing it, because it's my information to do what I wish. But they were sharing it before they shared it with me, and that's not okay, imo.
London Hipsters Lose to Cambridge Labs in Venture Funding
I think a lot of us who're heavy into IRC/IM have developed this habit, but it's important to be conscious of it and recognize that the "enter key is not punctuation", as one /topic puts it. I agree that in some contexts it is more effective to write that way, but it's a habit that can come back to bite you if you do it in the wrong context.
> But arguing that the only viable solution is to shut down a comparatively cheap and (full disclosure: I'm a customer) really quite entertaining service seems wrong to me. It's a net good; some people (hi!) like it.

That's not what's happening. You're not stupid, and I'm surprised you see it this way.

23andMe are being asked not to market their product in the way they are marketing. Or, if they want to continue to market like they are they have to have the same level of regulation as all other medical device suppliers.

Neither of those stop you from using their product.
It may well be similar material to Ng's Coursera course, but the table of contents on the right shows that this is obviously going to transition into the topic of deep networks -- part of Ng's research but not his Coursera course.

The training data is the MNIST dataset released by NIST some time ago, anyone is allowed to use it. It truly is no surprise to see it here, as it is very a very commonly used dataset in ML tutorials/books. It receives some discussion in Artificial Intelligence: A Modern Approach by Russel and Norvig, and even in the Theano getting started tutorials.
Its obvious that there's a ton of money in selling people's information for advertising, but I don't think that people are even that angry that their information is being sold so much as they aren't aware of what information is being sold. I think that it'd be interesting to see more transparency in selling of information so that target advertising can still be easily done which allowing the users to actively choose one product over another if they don't want their email addresses being given out as compared to cookies for search relevancy or something along those lines.
What I have noticed is that the period assumes a meaning, despite the traditional syntactical one, depending on the situation.

On the article's example a period means an non-friendly way to answer (like being 'pissed'). In other cases I've noticed that the period assumes the meaning of talking seriously (since it's more formal to use it). In other cases I've also seen having the meaning of sureness (like when we end a sentence with the word 'period').

In a nutshell: the period has a meaning of completeness; what I've said ended just there. In a informal conversation, where period is not required or it's not traditionally used, using it acquires a meaning. And this meaning is completely dependent on the people and the subject involved.

I love these subtle differences in the way we communicate. I'm not only not against it, as many people are, but I also nourish it. It's more fun, more clever to do this way. Why not to say it: more humane.

I love language hacking...
Eh, not really. I don't think any form of electronics is recyclable, best you probably get is third world countries burning the boards to get the gold out and killing themselves with the gases produced.
I bundled it in a git repo to make life easier :)

http://github.com/gardaud/endoh
The diff algorithm is a bit weird
Fast Food For The Mind
Here are a few things that work for me:

- Exercise in the evening. Helps work off the excess energy.
- Eat early and light dinner.
- Wind down activities early & unplug after dinner so that your body has a chance to relax.
- Set an alarm and don't snooze it. Better yet, restrict the number of snooze (most alarms on smartphones allow you to do that). And set a follow up alarm for your next activity that is soon after the first alarm. This will help with getting a schedule going.

All the best.
Seems like a money laundering op from the blurb. Any criminal record?
Debunked: http://www.reddit.com/r/Bitcoin/comments/1reuwq/vigorous_deb...
Actually, that's due to Drive trying to support the system clipboard intelligently (e.g. such that if you pasted into MS Office, you'd actually get a table/cell structure, rather than just text). Browser APIs don't provide support for that level of copy-paste, so it has to be worked around.

Plain text copy and paste works fine without.
why would one use it over stackphp?
Or the dash-heavy version you always run into once or twice a day (and bugs me):

I'm gonna give up on GTA IV - I just can't get into it - especially after playing V
Were you born in the US after 1963? If so, your state of birth probably already screened you for genetic diseases at birth:

http://articles.latimes.com/2013/jul/19/opinion/la-oe-timmer...

Parental consent is not required – though with enough advance effort and written request, opting-out is possible.

Further, many states retain the "residual dried blood spots" for more than 6 months and perhaps indefinitely:

http://www.ncbi.nlm.nih.gov/pubmed/16737872

So a sample of your genetic material may already exist in a state government filing cabinet, somewhere. In California, the retained information and sample can be used "for medical intervention, counseling or specific research projects which the California Board of Health approves" and "anonymous research studies". See the section "Storage and Use of Dried Blood Spots" at:

http://www.babysfirsttest.org/newborn-screening/states/calif...

For newborns, the California program currently tests for 79 different disorders:

http://www.cdph.ca.gov/programs/nbs/Documents/NBS-DisordersD...

And the per-disease records are apparently kept for lookup-by-individual without retesting, because there's a routine by-email process for requesting long-ago sickle-cell results (back to 1990) about NCAA student athletes:

http://www.cdph.ca.gov/programs/nbs/Pages/NBSFAQTraitAthlete...

And that's not even considering all the health procedures (blood donations, tests, surgeries) or natural shedding (hairs, skin, saliva, excrement) routine in a normal life. You are a firehose of genetic samples, to any even slightly attentive observer, or even passive observers who take an interest some time later.

So: good luck keeping your genes from the state, if it really wants them.
Thanks for those words and that link.

I like that way of thinking of it, I see it as just reusing the existing stack frame as a call in a tail call position doesn't need anything from the current stack (returning to this frame adds no extra meaning to it).

Having never implemented them though I feel like my ideas still need some fleshing out, my naive approach seems to be similar to the idea of trampolining.

Really looking forward to reading the linked document, very thorough and looks to be just what I was looking for (it even covers architecture dependent aspects!).
Running a 2400 Akka Node Cluster on Google Compute Engine
Oh nice, so the ads will be for things I'm actually likely to be interested in instead of random things I don't and will never care about?
That's not the case. Read the documentation on the site:

> The Google Wallet Card is funded by your Wallet Balance. Money is added to your Wallet Balance either by someone sending you money via Wallet or Gmail or by adding it yourself from a linked bank account or from a credit or debit card. The card has no fees to order and activate. There are no annual or monthly fees for the Google Wallet Card.
Sadyly, yes.

"Google Wallet Card is only available to US residents."
Hi there,

Probably the best in-depth book on this topic I've read is this one. I'd highly recommend it. http://www.amazon.co.uk/Payment-Systems-Macmillan-Financial-...

(Disclosure: it was co-written by one of my colleagues at IBM)