skysight-inc/HackerNews huggingface dataset:
Seems like the problem was addressed immediately. This seems like a success story of 23andMe.
I find this to be more true when using short phrased, singular thoughts. With shorthand being more common in IMs and texts, a single period may be a misinterpreted that they intend the entire conversation to end, not just one message.

"k." being the worst offender imo.
> every office/home office has a continuous webcam feed going on over google hangout

We've talked about doing this with my all-remote team, but it seems incredibly invasive. How has your experience been?
I have no issue believing that there are occasionally issues with permits, and that they might sometimes prevent neighborhoods from getting a certain kind of service

But given that Verizon is not rolling out any more FIOS nation-wide[1], I really have trouble believing it's a regulatory issue in this case. And they slowed down way before 2010[2]. VZW gave up on FIOS, plain and simple. Everywhere.

[1] http://www.dslreports.com/shownews/Verizon-Again-Confirms-Fi...
[2] http://www.huffingtonpost.com/bruce-kushnick/the-great-veriz...
No, not really.

About being too complex to be controlled, yes maybe, but there is very good people controlling complexity.

I know lots of entrepreneurs, as I am one myself.

The best entrepreneurs will learn from other people. Take for example Steve Jobs, he was not born knowing it all, he had fckng Robert Noyce as mentor, and all his life was spent learning from the best he could, like Polaroid inventor or Sony founder.(every year he will take 100 people from his company to learn from)

No matter were you are, there is always someone 10 to 20 years over you on a topic, and the best thing you could do is learn from them instead of thinking you are inventing gunpowder(Spanish expression that means you are inventing something revolutionary nobody knows about).

I personally know a man called Warren Buffet. This man, who is super rich old(normal old people believe they know it all) and famous will cold call you if he is interested in something you do for please explain it to him, and then he will start asking you deep questions about your business like crazy and if you ask him, he would do the same for you for anything you ask. This man has amazing amounts of valuable knowledge. In public he could not say what he really things because his word alone is capable of making markets go up or down.

Successful people do something called "masterminding", that is very similar to "pay it forward" in Silicon Valley. They learn form each other what works and what does not. They do it officially or by networking and just talking.
I wonder how Steam reviews will factor into the ratings on steam?
The period is not aggressive. The period implies a complete thought.
I do a lot of Wordpress development for clients. I've spent more on themes (between $30 - $80 per theme, usually closer to $40) than I have on plugins, and the themes often include functionality I'm looking for that I might otherwise use free plugins to create in a theme I'd build myself.

So far the main plugin I've spent money on is Advanced Custom Fields, purchasing the repeater field and options page add-ons. Cost around $40 USD I believe. Gives me a license to use those add-ons on as many client sites as I want.

I've also had clients purchase WooCommerce extensions like the PayPal Pro gateway ($79) and Stripe extension ($79).

Also, as I continue to build out http://BostonStartupsGuide.com, I expect I'll purchase SearchWP ($25) and Events Calendar Pro ($65).
In fact, a true meritocracy in a very competitive field is more likely to exacerbate the differences that already exist in society and result in an extremely uneven distribution. In a non-merit based industry uncle Bob can get a top job for his 3 children, and his friend's children regardless of gender, race, and any other characteristics. He can also appease reporters that criticize the distribution of his company and hire more people in the less represented populations to correct the problem. In a purely meritocratic field uncle Bob has no influence, no control, and each of the kids has to fight his or her way in. All uncle Bob can do is pay for the best education and the best opportunities for his children to compete in the meritocracy. To the extent that there are small inequalities among the population, those with the most resources will prepare their kids best to compete, and those kids will be over represented in the most competitive fields. The fact that the tech industry is dominated by white males only indicates that it is very competitive, and that white males historically have had a leg up in American society. A leg up that the meritocracy is quickly erasing.
Because then politicians would be considerably more likely to accept bribes, and only the uber rich, upper class, indenpendently wealthy people would be able to be politicians.

But that happens anyway. Look at the "socialist" president of France. Four houses (three holiday homes on the riviera), millions of euro personal wealth...
More like looking at it in the wrong reading frame.
Not currently, but the system is open source and designed to be easily extensible.
I think $100 is too aggressive a number and everyone seems to have fixated on that.

I'm saying there is a number between $0 and $1,000,000 per call that will help reduce false positives and make the system more efficient. Maybe its $100, maybe its $50, maybes it $5, maybe its $0.

I've always appreciated what London did to solve its traffic congestion problems (http://grist.org/news/the-success-of-londons-congestion-char...) and while I understand they are not truly analogous, I'm a believer in using $ to properly align incentives and make a system more efficient.
You can email info@rsync.net.
I would argue that first startup needs to spend the extra time or hire another developer if the end result otherwise is something as egregious as what QuizUp appears to be doing.

But I agree, there's a huge difference between just not being able to implement security and not considering it relevant. To me, this is clearly a sign of the latter.
I think the date of copyright is supposed to be the date at which content you are copyrighting was first created and anything after that date is covered. Not certain though
Bitcoin creator may have ties to Silk Road founder
Why? I try to use Google services as little as possible because I feel like they don't respect my privacy. I think it's reasonable that people who bitch and moan about Google but refuse to seek alternatives (they're out there!) are a part of the problem, not a part of the solution.
Strangely everyone is fine with logging in your cellphone which is even more broad.

I log with my Google Account and I can use all Google Services without logging in, that's great, why can't we have that on the Desktop?
> ...doesn't mean that women aren't benefiting from the halo effect of meritocracy in SV.

You haven't provided any real evidence of the existence of a "halo effect of meritocracy" that is benefiting women in Silicon Valley.

There are lots of women who are well-compensated outside of Silicon Valley. Have you never met a female lawyer, doctor, investment banker, accountant, dentist, real estate agent or small business owner who lives and works outside of this area?

> It's almost ludicrous to use what is basically a black-swan, lottery ticket winner as some sort of point of comparison for progress.

That is a reasonable argument, but just because you can show that this is a less-than-convincing way of debunking the notion that Silicon Valley is a meritocracy doesn't mean that you have proven Silicon Valley is a meritocracy.

> The real story isn't that there aren't enough of these female lottery ticket winners in SV, it's that if you are a smart and hardworking woman, you can make a lot more money than most startup founders ever will.

You keep pot-shotting "startup founders" but it's not clear what point you're trying to make.

Given the high failure rate of new businesses generally, you're not saying much by pointing out that it's easier to "make a lot more money" through gainful employment than entrepreneurship. Heck, a person making minimum wage is earning "a lot more" than the broke, couchsurfing founders you will inevitably meet from time to time in Silicon Valley.
Although the doctors and nurses were taking care of this woman as best they could, their ultimate goals were purely monetary based on her large wealth.

Sad.
If I were to ever use 23andme, I'd use a fake name, a disposable mailing address, a fake email address, and never, ever discuss it with anyone.

Your genome doesn't change, and who knows where that data leaks to later? Who knows what healthcare providers will vacuum up such leaks?

Who knows what kind of discriminatory practices will be undertaken by service providers, insurers, or even employers in the future?

Haven't y'all ever watched Gattaca?!

Keep your private information private. Nobody else will do it for you.

EDIT: Oh, and USA PATRIOT too.
>Elsewhere in consumerland, the product is sold, and independent testing is performed on off-the-shelf samples

Not true.

Do you really think I can start legally marketing a car seat or a crib without safety testing it first? Wrong.

http://www.cpsc.gov/en/Business--Manufacturing/Testing-Certi...

Federal law requires manufacturers and importers to test many consumer products for compliance with consumer product safety requirements. Based on passing test results, the manufacturer or importer must certify the consumer product as compliant with the applicable consumer product safety requirements in a written certificate that it must provide to retailers, distributors and, upon request, to the government.
> But who goes to the doctor to confirm a false negative

The same people that goes to doctors and dentists for regular check-ups without suspecting anything wrong.
They must weigh them or something. When I rolled my own change once I was short 1 cent in a dollar penny roll and they sent me snail mail about it.
>Google would still make plenty of money from AdWords.

Of course they would.

And McDonald's would still make plenty of money if they were forced to pay a decent wage, and banks would still make plenty of money if they were forced to be more responsible and lower fees.

But you don't see that happening, because the drive for more profit is all consuming, and it's the corporations that have the most influence in these laws.
Most of the articles posted here are about making money, although they are biased towards making money with technology. This is more of a "hackers who want to start companies" site than purely a hacker one. Considering how many of the people on this site expect to be ridiculously wealthy at some point, I'm not surprised that a story like this made it to the front page.
About what percentage, would you say, of 23andme's clients are both equipped and inclined to educate themselves in bioinformatics, to the degree OP did, to the extent required to replicate 23andme's sequence analysis and identify errors in their results?
Show HN: Science News - HN Clone Built With Drum (my first Django site)
Apple Buys 3-D Sensor Company PrimeSense
When you've been relying on a service for a while and the TOS suddenly change it seems fair to complain: OP would have probably picked a different service if he knew.
23andme is a consumer genetic testing company. The testing is not meant to be clinically applied. I work for a company that is similar to 23andme, different in the sense that the test can be clinically applied; the catch is that everything you report must be very robustly researched and you must comply with more regulation (research, lab, medical, security, etc.) which drives up the cost but gives you much more actionable and medically relevant information.

I think there are benefits to both approaches of genetic testing; 23andme has a lot of data it collects and can do interesting statistical studies/reporting that other more research-oriented companies cannot. However, like I said before, you can't view a test like that as medically actionable. In the end though, the more testing there is (as long as the messaging is clear and consumers do their homework), the better oFf the world will be.
None. If I don't find one I like that I can use for free I write my own.

<shameless-self-promotion>

http://wordpress.org/plugins/kennethrapp

</shameless-self-promotion>
Exceptional re-link: SETI at home could be the smartest idea NSA ever had
Sorry for re-linking[1] to a HN post I posted two days ago, but I'd like to exceptionally take the chance to give this a bit more visibility (so to hear your opinions), because when I first posted it I erroneously decided to send it late at night and very few people could see it...

So I hope you can forgive me..

Also, the argument of the post itself it's not even based on a proven fact(!), so I am guilty two times, but hopefully this could sparkle an interesting, constructive and maybe enlightening debate.

Here it is:

[1]
https://news.ycombinator.com/item?id=6792210

Please comment there. Thank you!
Your #1 is most of the explanation; Phil is a net.personality from way back ("Travels with Samantha", 1994), as well as a pithy writer of several perennial pieces of HN text (like: http://philip.greenspun.com/careers/women-in-science).
Take your startup to the next level
23AM just got a smackdown letter from the FDA about that:

http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/2...
here some links,

http://oz.stern.nyu.edu/io/network.html

http://sidestepandtwist.com/

and don't forget Google is your best friend...
Unexpressed disease genes has been an issue from the beginning of human sequencing. The 3rd human sequenced James Watson had almost 30 unexpressed disease genes, including retinitus pigmentosa. No one understands why this occurs.
I made this for a senior design project at UIUC. No web interface though. You controlled the robots via wireless sensors I designed to be worn on your arms.
Searching Google with daterange syntax flags you as a bot
Yahoo hires Katie Couric from ABC News as Global Anchor
I interpret the lack of capitalization and correct punctuation as a sociopathic desire to undermine the very foundation of modern civilization--by destroying written language as a medium of communication. So in a way, I am pissed when I end a sentence with a period: I'm pissed at all the people who can't be bothered to use one. And when I use colons and em dashes, that should be interpreted as hate crimes.
I thought that was covered by the "go to the doctor" bit. The doctor would, if even remotely competent, verify the presence of a disease before beginning treatment.

For all the hoopla I keep hearing be attributed to malice regarding 23andMe's results, honestly, I think the results, at the least, encourage people to go to the doctor.

My father-in-law was diagnosed with cancer a couple of years ago, but because he was regular with checkups, they were able to catch it early, and he's been in remission for over a year.

A false positive by 23andMe regarding one's predisposition towards cancer should motivate them to the doctor more often, which would indicate whether they were or were not cancer positive -- but in the event of either, I'd wager that more frequent trips to the doctor would be a net benefit.
Do we really need this comment in every google thread? Does anyone here actually think that there's no alternatives to google or are we just circlejerking with the slowly (and seemingly endlessly) moving off google conceit.
The book being reviewed here is one I've been meaning to pickup and read for a while, just been lazy about it. Huguette Clark was literally a living fossil - possibly the very very last holdover from the gilded age, really a very sad story. Though by all accounts - she was happy largely - so maybe not so sad in absolute terms over all.
Crazy idea: How about, instead of getting this report ourselves, we have it sent to our primary care physician.

That way we don't have to stress that there is some likelihood that we might get some dreaded disease but our doctor could talk to us if the risk is high enough or if we start having symptoms that match one of our genetic risk factors?
I signed up for 23andme.com a few months ago, mainly because I'm adopted and I don't know anything about my family history, so I thought it would be neat to check out. The one and only thing that bothers me so far is their definition of privacy. Here's what I mean:

One of the features they provide is ancestry help. They compare your DNA with all other users' DNA and then give you a list of potential relatives. They say "hey, you guys share .6% of the same DNA, you might be 3rd to 5th cousins."

That's cool, right? Especially for someone who is adopted.

The problem is that it takes 2 weeks longer to do the ancestry stuff than it does to do the medical stuff. The medical results showed up in my account about 4 weeks after I sent off my spit-filled test tube. The ancestry results showed up a full month later. In the meantime, between medical results and ancestry results, I'm getting "friend requests" from other users. There are no messages attached to these users, but I presume they believe, somehow, that they are related to me.

How can this be? I hadn't yet received my own ancestry results.

I emailed 23andme.com support, and here's what they said:

> Thank you for contacting 23andMe.

> If you've been genotyped through our service, you can share your genome with other 23andMe users and compare yourself with them using our various features.

>This is of special interest to members who are interested in their family's data.

> Due to the way our computation process works, some of your relatives can actually see you appear in their list of DNA Relatives before all your results are uploaded.

Let me repeat that last part:

> Due to the way our computation process works, some of your relatives can actually see you appear in their list of DNA Relatives before all your results are uploaded.

So get this: my name and some level of my DNA results are shown to complete strangers, and not only that, but they are shown before I even get the information.

That bothers me. That bothers me a lot. I haven't yet decided what to do about it, but believe me, I've spent a great deal of time considering this since it happened.
Ask HN: Best way to broadcast live tech meetup?
What are the best ways to broadcast any tech talks live and then host those tech talks afterwards?
The news came out some time ago but today Apple and PrimeSense confirmed the purchase.

Given that PS's new Capri sensor (http://www.primesense.com/solutions/3d-sensor/) can be easily incorporated into a small set top box, this gives an indication that Apple plans to take Microsoft's Kinect controlled TV experience: either with the long-rumored TV set (http://www.theverge.com/2013/11/11/5091696/apple-hdtv-plans-...) or with a souped up Apple TV design.
There is a difference between mechanical analysis and medical analysis. Obviously they need to analyze the raw signals coming out of the machine to figure out what markers are present. But they could stop there, saying "with four nines certainty you have genes ABJ2, CBI8, LOC9, JOLO, ZZT". The FDA is objecting to doing a medical correlation/explanation beyond that point, doing the things WebMD does.
Sometimes we can't all be the guy we want to be.
There are alternatives to hashing proof-of-work. Two interesting ideas are:

- Peercoin (http://en.wikipedia.org/wiki/Peercoin), which introduced an alternative concept called proof-of-stake, which essentially dismisses mining in the long run

- Primecoin (http://en.wikipedia.org/wiki/Primecoin), for which the "work" is engineed to be scientifically useful (I'm not sure how useful it actually is)

I really wish the Bitcoin community had seeked more ingenious/efficient alternatives early on... a lot of energy is going to waste now.
Yes you have just lost the "pre-existing conditions" battle with your insurer if you do this.
Psychedelic drugs. They help keep priorities in order and aid creativity by forcing you to examine different points of view and approach problems from different angles.
So what, the existence of something worse doesn't make this better
Effort does not correlate exactly with results, but the chances of success are high if one tries and is capable.

In both tech and hustle, it's easier with wealth, privilege, connections, luck, and/or friends.

But large swaths of tech and hacking can be done on a $200 netbook or a lab of $100 used notebooks.

The hustle part... That's easier if you have hustle. If you are a geek, make a tool that's needed and sell it to another geek.

I've seen male, female, black, white, mongrel, rich, poor, and those with role models and without success at tech and business. It's harder without but still possible.

And I think SV may indeed be the best place in the country to succeed in - in gambling terms, the result converges faster with the expected value given effort and application.

Particularly (in my opinion) because past failures are discounted and companies, especially startups, are willing to give startups a try without as much suspicion.
Similar story. It took me about two years to fully "feel healthy" after a (or possibly many) rugby concussions my senior year of college. The day after my concussion, I felt drunk, wasted actually. When I woke up and went to the bathroom, I had to lean my hand on the wall just to stay upright. I was wobbling around campus for about two weeks after the incident. Always off balance, pretty much worrying the entire time that my CT scan and MRI's missed a brain bleed. I shouldn't have felt this weird, but they continued to say everything was normal. That was the worst part: The feeling that something was terribly wrong, but every single doctor told me that I was fine.

Five years later, I feel relatively okay. I barely ever notice any lasting affects of the concussion. Every so often, I have a bad delay in recalling a word I am thinking of. One beer makes me feel really weird, although the feeling seems to go away after having two or three. And ejaculating, for some odd reason, gives me a headache.
Sorry, fixed!
Advance Your PostgreSQL skills
You can potentially predict a male's surname from a DNA sample. The accuracy is roughly proportional to the frequency of the name.

http://www.sciencemag.org/content/339/6117/321.abstract
Why the snide remark? Was there something unreasonable about what he said?
Better that a CIO gets a "CEO page" than a CEO gets a "CIO page" :)

Ironically, I'm the CEO here and I wouldn't want to see any of these ...
More often than note prestige is something someone is born into rather than earned.
I'm amused how much this is being upvoted, when it was died a few days ago with no decision. Then again, a few days ago no one had changed the title to mention launching nukes.

Since I'm assuming a CloudFlare person is watching this thread, I've been a bit curious about when they plan on releasing that database of SSL certificates they promised almost a year ago.

> Going forward, in addition to releasing the directory of intermediate SSL certificates on Github, we plan on releasing our SSL bundler as a free service so you can package up your SSL certificates as efficiently as possible, even if you're not using CloudFlare. Just one more way we're working to make the web fast and safe.

http://blog.cloudflare.com/what-we-just-did-to-make-ssl-even...

That looks like a very cool project, and they got a decent amount of attention over it. It would be nice to see some follow through on those plans to release it.
"I think my TV is spying on me."

90's: "You should talk to a psychiatrist."

2013: "You should talk to my cousin Ernie, he's an IT whiz."

via https://twitter.com/kennwhite/status/403584069923270656

Says something about whats happened in technology and privacy over the last few decades.
Re: lists, you have two options. Either add another linebreak in between each option (they'll be formatted effectively as paragraphs) OR indent the block by four spaces and format it however you want (it will become a code block).