skysight-inc/HackerNews huggingface dataset:
There is a fair share of ignorance of stats to go around, but in the biological sciences and in medicine, getting a big enough n is often practically difficult or impossible. Sometimes it's funding for the study that is to blame. But biology is messier than we often like to admit to ourselves. Sometimes it's just hard to get the materials. I was in a session just this week that showed a gene therapy cure for two kids who were cured of lysosomal storage disorder. It was incredible. But still an n of 4 I think. The process of growing the cells and transferring the genes is so time consuming and difficult, that's the best they could do. That's an extreme case to be sure, but even more mundane stuff can suffer. For example, if your study requires a muscle biopsy instead of a blood test, your n is going to be lower because muscle biopsies are a tough sell to patients. People, animals, and cells are all a lot more fickle than bits and electrons most of us around here are accustomed to working with.
Haha so true, RIP.

Thankfully his responses are saved for posterity in the imap-protocol discussion list archive. ;)

https://mailman2.u.washington.edu/mailman/mmsearch/imap-prot...
Particularly when comparing it to tylenol.
Probably just hitting the fd-per-process ulimit
you are right but I'll still use async over sync anytime... :)
A lot of people (myself included) either just don't like Facebook, or use it only very sporadically. It's not like you can count on people being logged in all the time -- and on top of this, be willing to share their FB identity with you, just to look at your app.

But the bigger question is: do you really need to have any kind of auth at all?

While you're still in the demo/outreach stage of your app, the important thing is for people to be able to just see the darned thing. Anything like a login is just way too much overhead. It should suffice to create an anonymous session ID, and go from there. And if you find people starting to abuse the site or eat up your resources with their anonymous sessions, well, you can take that as a sign that you're already successful :)

But even if you feel you absolutely must require a login, at least you can have a static "take a tour" section with some canned images and slides. Again, what most people want is just to get an instant idea of what your app is about -- with as little time investment as possible.
On which stocks are most affected by the fed, see my reply to the other reply (which makes roughly the same point) here https://news.ycombinator.com/item?id=6623769

On the evidence you are presenting: This doesn't prove that the Fed is causing a stock bubble. The stock market, if anything, is forward looking. Even if the fed was causing a bubble, the kind of patterns you are showing wouldn't be expected. Take the second link, for example. The article clearly states that the stock price gains are made before the FOMC announcements. So somehow the act of making any announcement is causing the market to react in anticipation.

I don't know how to explain these patterns, but they are certainly not good evidence for the Fed causing a bubble.

Monetary policy is very simple and in accordance with the best macro theory we have. The Fed lowers interest rates in recessions, in the hope that it will cause people to consume/invest more and "save" less where saving might include holding hard currency, or safe physical investments. Put in more conventional language, the Fed lowers interest rates to stimulate economic activity.

But this should not be interpreted as trying to cause a bubble. The aim of the Fed is to stimulate economic activity so that both the current efficiency of the economy improves, and beliefs about the future efficiency of the economy are more optimistic. In doing so, it hopes to cause the economy to move from the "unnatural" state in which people are fearful about the future, expect high interest rates, and are unwilling to invest or consume, to the "natural" state in which people are optimistic about the future and expect low (short and medium term) interest rates.
Indeed there are! Here's a short Wired article I saw about the concept a few months back: http://www.wired.com/wiredenterprise/2013/07/buttonwood/

One of my clients actually said to me, at the closing of a project: "I don't know if you take bit coins, but I'm gonna go see my bitcoin guy in a few. I don't like to buy online. Anyway, if you want to be paid in bit coins, let me know! Otherwise I'll drop the check in the mail tomorrow."

(that's paraphrased a bit, as I cannot remember the exact wording, but the meat of the quote is the same.)
looks like a chat icon (someone's head and shoulders in silhouette). is it similar to kopete's? [edit: nope. no idea what it's reminding me of, but sure i've seen something similar]
It's Python humour.
Live migration is useful, but in my opinion it's kind of a band-aid solution for the problem of availability. Live migration is not necessary if you design your application as a distributed system.
carbs + saturated fat = cholesterol

choose one
BoxGrinder - Create your own Virtual Appliances
I'm a little ashamed to say that although I've heard plenty about Pandas, for some reason I've remained adamant with data processing for my PhD reason to hack ugly solutions using numpy array of arrays, complicated structured arrays etc. instead of just reading through a Pandas tutorial.

Damn.
...refined carbohydrates and sugar in particular are actually the culprits

Adopting a Mediterranean diet after a heart attack is almost three times as powerful in reducing mortality as taking a statin, writes Malhotra.
This article only considered the point of view of the person being unfriended. There are very good reasons to keep unfriending secret on the side of the unfriend-er.

Lack of secrecy will make people less willing to unfriend because of social embarrassment or other reasons. This is a bad thing as people will end up leaking personal info because of awkwardness.

Imagine an old school friend is stalking you. Conventional advice is not to interact with a stalker but to ignore them. Unfriending makes sense but if does/could send a message to the stalker could make a situation worse.
Well the stronger companies will survive and thrive, with their competitors destroyed. Amazon benefited from that survival effect coming out of the dotcom bubble and crash.

These Fed driven asset bubble waves are a huge wealth give-away to the biggest companies. They tend to be able to ride out the ups and downs, while their smaller competitors who get caught up in it as well, do not tend to survive the extreme down-turn (take Sun Microsystems for example: they modified their business to ride the exaggerated dotcom boom, their stock was worth $200+ billion at the peak, and their sales grew massively, and then it all imploded and nearly destroy Sun on the way down, and some would argue it did in fact; meanwhile Microsoft rode it all out just fine).

Lesson being, some companies get caught up in the exuberance, and they roughly speaking get destroyed, while their competitors thrive in the post-bubble period when the stock market & private markets aren't willing to fund competition any longer.
Thanks, that makes more sense :)
Well, you can sorta already do this in a limited manner with Android.
http://goo.gl/NH8Wmt

But I guess you mean you want hardware access from the web app itself?
http://docs.webplatform.org/wiki/apis/geolocation
http://www.w3.org/TR/2010/WD-html-media-capture-20100928/
http://www.html5rocks.com/tutorials/device/orientation/
http://developer.android.com/guide/appendix/g-app-intents.ht...
http://docs.webplatform.org/wiki/apis/file

While this doesn't cover 100% of possible use cases, JS APIs are getting there.
> Public funding for science is frozen or being cut, private R&D labs are shuttering their doors, and companies are increasingly concerned with quarterly results at the expense of long term research.

It's ironic that Silicon Valley owes most of it's existence to investments by the DoD and ARPA. Most of the technology we use in the electronics industry today would not exist except for all the public money that was poured into semiconductor research. Slashing public funding, especially of fundamental research, is one of the worst things we could probably do for our economy's future.
What you say is all true.
And what I say is true also.
You're just talking from Facebook's point of view, and i'm talking from investors' point of view, which is what the article is talking about. As I also mentioned, it is unlikely that it will happen, but from an investor's point of view you cannot deny that it still is an existing risk. And I don't think it's nice to downvote someone else's comment just because you disagree
Of course. see e.g. https://localbitcoins.com
I wonder if you can use Cain and Able and log everything from that signal using arp poisoning.
Ask HN: What are good questions to ask during the first week of a new job?
I start a new job this week and would like to set myself up for success. What are some questions I can ask of my colleagues and manager to get things off on the right foot?
Most things in the biological sciences are correlations, to be as precise as we are in the sciences, you have to point out that some relationship is correlational unless you specifically test for causation (which is unfeasible in most cases)...if you assume causation, even when there seems to be very little doubt as to the causative agent, your paper is going to get sent back to you by the reviewers (in most cases).

Add to that the fact that recommendations are based on erring on the side of caution, and that tight correlations do become predictors of an outcome, then you have a recipe for these recommendations. Nothing bad is going to happen by reducing saturated fat intake, for the most part, but there is a chance of it if intake is excessive, and in fact saturated fat intake is a fairly strong predictor of future heart incidents.
Nice to stumble upon forever.fm on this thread. I like it a lot and been listening to it for some time.
The problem with Python and its many IDE's is they still rely on textual code visual-sweeping. For example, you see import random but there is no shortcut to browse the random classes and methods. The same with all imported libraries. I am suprised how easily developers approve the old command line evaluator as comfortable. Try to rename several .py files while they are opened in your IDE and see what happens. Unacceptable for this age.

And there is the thing of terminology. Object inspector is just accessing method signature comments and parameter documentation. There is no real dynamic object inspection or retrospection in Python. And its MOP is extremely hard to use compared to other reflective languages. Sorry guys, but Python and IDE's still repeats a lot the same ideas.
Obama Unaware as U.S. Spied on World Leaders: Officials
Are nicotine skin patches causing an epidemic of skin cancer where they are placed?

Not all side effects are caused by the active ingredient.
it's a constant battle. sometimes you have to compromise, sometimes you can claw some time back to fix up previous compromises.

finding the right balance pretty much defines what being a good professional software engineer is, imho.
> We’re only at 10^7 so far. As Heninger said in her talk, we have enough 512-bit primes to assign a public encryption key to every atom in the universe, with little worry over possible duplicates.

I find the scale of these numbers absolutely incredible.
The Zombie iPad 2
I think you are now the one doing the over-thinking.

You are applying a model with fixed r, which is wrong because the current low interest rates are temporary.

Forget the interaction between interest rates and risk preference for the moment. Isn't it the case that if interest rates are certain to return to normal in 2 years, then the values of an investment that returns in 5 years, and an investment that returns in 2 years, will be equally affected by current low interest rates?
There are a lot of issues flying around that are being inappropriately mixed up for all sorts of political purposes.

The Begley 'study' is impossible to assess, because they didn't report what the studies were, nor any of their methods, or anything. It's BS and hearsay, not science. Moreover, according to the Begley article itself, "The term 'non-reproduced' was assigned on the basis of findings not being sufficiently robust to drive a drug-development programme."

Nobody said that the purpose of every single scientific paper was to enable Amgen to go start a drug-development program.

There are many problems with the science funding situation, the glamour pub game, excess hype, funding getting sucked up by mega-projects, lack of open-access, inability to publish negative results, etc, etc, etc, but in general, it is not true that scientists are making up sexy results to get them into Nature and Science.
Ask about almost everything. Workflows, who to talk to to make things happen, etc. Seriously, ask about everything. It doesn't make you look bad (unless you keep repeating the same question and don't get any work done).
Applying to Ph.D. Programs in Computer Science (2011) [pdf]
"I think part of the reason a lot of people don't take Kanye seriously as an artist is that he behaves like a petulant twit."

But the thing is, people DO take Kanye seriously as an artist. His albums are constantly praised over and over again by critics. Even in places you wouldn't really expect it, there is a general acceptance that Kanye is leading the pack when it comes to innovation in pop music.
Guido van Rossum (inventor of Python)... ok, talk to me when the inventor of your favourite language has won a Turing Award.
A related pet peeve:

It's becoming difficult to find products with "all" the fat (vs "low/reduced" fat). Prime example for me: chocolate milk. It's pretty rare nowadays that I ever see anything over 1% milk used in it -- and of course the label touts the low fat formulation, but doesn't mention there's more sugar pumped in it than a can of soda.

Even if this was healthier than full-fat/less sugar chocolate milk, I'd still resent it. Chocolate milk is a treat, not a dietary staple. People should know that. Make it that way, market it that way.

But it's starting to look like it isn't healthier. Which makes the marketing more misleading and the formulation pretty ironic.
I upvote a submission when it's interesting enough that I don't just skim it, and also to keep the submission in my saved stories.
Unless I misunderstood, they know which keys belongs to which houses. They successfully factored those keys, and unless they threw the metadata away they still know the domain that is using that key.

And if they did throw the metadata away, they still have this pile of 64,000 prime factors. They can ask the domains for their public keys again and test if any of those factors matches.
Yes I have heard this too. Basically, the receiver is with their partner, for other reasons. And hence tend to downplay the significance of the violence.
I consider this a feature, not a bug. If you've gone that far into the pages it is time to get off hackernews and get back to work.
This is as complete a misreading of Reed's review as I can imagine.
Agreed. It's not just celebrity deaths it's more and more obviously not technology-related topics. It's a shame because the interesting technology topics are buried in an increasing amount of noise.
That would make sense if the penalty of finding a tainted batch were to send it back for another one. However, the case is that if you ever get caught selling tainted products you could get shut down completely.
You don't want to hard-link backups to the non-backup copy -- the non-backup files might change, and if it is a change that doesn't remove the file first, it will modify the backups if the backups are hard linked.

Doesn't vim intentionally do this if it edits files that are hard linked? emacs breaks the hard link. I'm not saying either behavior is best, but in this case one might be surprising!
The absolute best thing about HN is that if you're a Hacker, it's a semi-complete resource of what's relevant. Not every celebrity death belongs on HN, but this one absolutely does. It's hard to explain why it does, which is why HN's rules are vague, but there's no doubt that it does. It may mean nothing to you, as many of the things mean nothing to you on the site (do you read every link on the front page? No way) but to a lot of the community, as hackers this was important to us.
I think the biggest issue is that high (saturated) fat is often combined with high carb (refined sugars, starchy foods etc).
My diet consists of high fat / low carb foods and it simply works (for me...). I've lost weight (without trying) and my energy levels are much more predictable and stable.
I never watch how much I eat because my body will naturally stop be from overeating.
Lucida Grande “Retina-optimized” in OS X Mavericks
> Nothing bad is going to happen by reducing saturated fat intake

From what I've read, it depends on what you eat instead. For example, as the article says:

"a JAMA study revealed that a 'low fat' diet showed the greatest decrease in energy expenditure, an unhealthy lipid pattern, and increased insulin resistance (a precursor to diabetes) compared with a low carbohydrate and low glycaemic index (GI) diet."
If we start to question artists morally then very quickly a lot of significant work and artists should 'abandon the scene'. From Lennon to Wagner, Ferdinand-Celine to Bill Murray, Polanksi via Woody Allen, to Chris Brown to Kanye (probably the mildest on this shopping list).
He does well. Music is subjective, but here's a glimpse at his creative process:

https://youtu.be/2L27MMkVl08
In case anyone [else] is wondering, RFC 1035 disallows domain names starting or ending with "-", so there is no registering C--.com, alas:

<label> ::= <letter> [ [ <ldh-str> ] <let-dig> ]

<ldh-str> ::= <let-dig-hyp> | <let-dig-hyp> <ldh-str>

<let-dig-hyp> ::= <let-dig> | "-"

<let-dig> ::= <letter> | <digit>

<letter> ::= any one of the 52 alphabetic characters A
through Z in upper case and a through z in lower case

<digit> ::= any one of the ten digits 0 through 9
Someone should make an app that aggregates a list of companies that pay for advertisements which are especially disruptive or annoying, so I can be extra sure that I'm not supporting their behavior.
I do first code. Then refactor. I cannot do clean, perfect code since there's always pressure from management. i try to refactor once I have everything working.
There have been a lot of people saying this for quite awhile. Malcolm Kendrick wrote an entire book about the poor science behind our current belief that cholesterol causes heart disease. There are many others. But in the current medical environment where doctors want to prescribe a pill to fix everything and the biogen companies have enormous influence over public policy, dissent never rises above the level of a whisper.

Smoking, cocaine, stress, these things cause heart disease. Saturated fat probably isn't even a minor issue as it relates to heart disease. Every day, millions of Americans take a pill to reduce cholesterol when it's not even an issue. But don't expect that to ever change no matter how many doctors start saying saturated fat isn't the major issue.
You could always resort to browsing using telnet or netcat, or write your own client in a few lines of your favorite language.
This is a great resource. Feels like the next step after Matt Gemmell's post "API Design" (http://mattgemmell.com/2012/05/24/api-design/) where he called APIs "UX for developers".
Just a quick note to say that i've found a workaround for this a long time ago - all you need to do is somehow import your facebook 'friends' list into your phone's contact book (i did it on android but i'm sure it's possible on IOS somehow) then when you open the app in the 'find friends' area it's going to suggest any contacts you have that aren't currently your friend on facebook. so anyone listed there has 'unfriended' you since the export. I'm sure it would be trivial for them to close that hole but it's also unlikely because they would want people adding as many real-life friends to their facebook friend list as possible. they have however actively gone after the methods by which you can export the current friend list and import it to the phone (it's in their best interest for this migration to be one-way of course) I think when I did it i used yahoo contacts but that one was 'closed' (sort of, there's still ways)
I would guess something like this:

http://www.youtube.com/watch?v=RDPzVdohrck#t=1m13s

Oh, and integration with the OS X recovery partition / OS reinstallation mechanism that allows you to point to a Time Machine backup as the recovery point for your re-installation.
CSS3: The Missing Manual - 3rd edition has some really good reviews.

But I'm somewhat in the same boat as you. In the past few months, I've been doing a lot more front-end development and trying to fill in those knowledge gaps - especially things like css layout.

But I would like really like to find a book or other resource on HTML 5 app development, not just one specific technology. I come from a thick client background, so a lot of front-end development is still painful for me and I would really love a book that presents all the technologies involved and best practices for large, client-side application web development.
You can see the big version of this icon on the openvpn site. The OSS image is similar just green without the lock.
> Sometimes it’s an accident, and they want to ask the person if they meant to unfriend them

This is just a recipe for disaster. If I unfriended someone and they messaged me asking for clarification, I'd just tell them I messed up so I wouldn't have to deal with the awkwardness. Heck, I'd stop unfriending people and just put them into a group that I exclude from all future status updates, etc. I'm not surprised Facebook shuts these apps down. In fact, I support them.
ArchLinux -- It satisfies my needs with the least hassle: I use a very heavily configured i3 setup that's tailored exactly to my needs for school and developing (Full DE's are clumsy and to slow on my cheap laptop), and I need recent versions of software for school IE. Eclipse since we're required to use it for Java, and LibreOffice for writing papers. Older versions of either one of those either don't work as well or don't work at all, as I have to transfer stuff to them from newer versions on school computers. (That being the newest Eclipse and MSoft Office).

I could use Ubuntu or Fedora or etc., but at that point I'd have to be continually updating to the next version to keep my software versions current enough to be used, and even then I risk my configuration breaking on the bigger upgrades and having to deal with that during the middle a semester, not very convenient. Arch has a reputation for being a lot of work, but as far as I'm concerned it's much less work to keep up-to-date then a Ubuntu install, at the very least Arch doesn't have massive breaking updates every 6 months. I have yet to have my Arch system totally crap-out on me, as long as I update my packages every few days or so, and check the Arch News before any upgrades that may cause issues, it's been extremely easy to maintain.
Checking MX records is super easy.

dig gmail.com MX
Speaking of Cale and Reed, I still enjoy listening to their 1990 album Songs for Drella about their time with Andy Warhol.

It's a very personal record, rather quiet, and gives a lot of insight in to who Warhol was from both Reed and Cale. Here's a sample, with Cale singing: http://www.youtube.com/watch?v=5FBvP8o35CA
What we did for Return to Dark Castle (which ran at a fixed 640x480, 16 bit color) is give the user the option to scale by nearest neighbor, interpolation, or both (mixed 50% with each other). The "both" option worked surprisingly well, especially since it was a "quick fix"!