skysight-inc/HackerNews huggingface dataset:
Surely part of the discrepancy in timing is indirectly linked to "importance", since we typically include "lethality" and similar measures into what we consider important.

Clearly a good chunk of the time spent in trial is to determine side-effects, contraindications and the like. Given that more "important" targets are also likely more "lethal" targets, then their bars for acceptable side-effects are surely going to be lower. I mean, who really cares if there's a potential for 5% of drug takers go blind, if the increase in survival rate over the current best option is sufficiently high.
Folks, monitoring communications is literally murder!
"the Java community's culture of complexity" -- great evocative phrase.
study from 2003, a little bit has changed since then.

but overall, it shows that using the market as a guiding principle for the selection of which drugs to develop works. it frees humans from making morally horrible choices. by being profit driven, drug development is automatically covering the diseases which have the highest number of patients and highest economic impact.

the latter is difficult to stomach, but from a purely scientific standpoint, which overlaps with the market, a western life is indeed worth more than an african one. simple to prove, kill 3000 westerners and the world goes to war. kill 3000 ethopians and the world goes meh.

it is impossible to target all diseases at the same time. also, through healthcare spending the world is signalling in cold, hard terms how much their health is worth to them. which leads to finite resources and, again, the horrible choice on what to try to cure. supply and demand, where demand is not only desire but backed by the economic means and will to spend it, works in this area.

as for the speed of the approval process - better safe than sorry. the only way to make it faster would be larger human trials, but who exactly wants that?
Paul Graham invented lisp… that’s when I stop reading
Somehow I would think it's also a bad move from Amazon as it hurts the perception of their brand.

I like to think of Amazon as a brand I can trust. Having crapware sponsored by Amazon on my OS hurts that trust.
Truth be told, you won't be able to call them 'communists' (evil or good) regardless.
they would have never been lost if sane copyright laws had allowed people to safe their cultural media.
Semi-automatic method for grading a million homework assignments
A couple of "snapshot" services which weren't mentioned:

http://www.peeep.us/

http://archive.is/
>One needs to maintain a clean-room environment, both for the protection of the mirror from dust, and of yourself from the abrasives.

That's crazy talk, and an impossibility. The stuff gets everywhere. It is a messy process. Here is a particularly messy example. https://www.youtube.com/watch?v=cukjxWCPVeg
I don't like this monitoring at this event, but it seems irrational to suggest that it will destroy one or more democracies.
Looks like the journalist was too young to remember the day when Microsoft announced this policy via email to everyone. I remember the days where I get reminder emails on my secondary account to login. It was always in their terms and conditions ever since. Certainly they didn't do this quietly. But yes, they do this, unfortunately.
Google Is Sneaking Chrome OS Into Windows 8's "Metro" Mode
> raising the required paid holidays
And thus reducing the part of the salary they get in monetary form.

> cuts in unemployment allowances
And thus increasing the part of the salary they get in monetary form.

> increasing the VAT
And thus making space for more government spending.

Those not as clear-cut propositions as you comment imply, and I'm now impressed by the amount of maturity the swiss population just displayed by making those calculations. I guess when you put some responsibility into the hand of The People, they stop acting like irresponsible children.
Facebook Requires Social Fixer Browser Extension to Remove Features
I haven't found that to be the case. We build machines, reinstall OSes, upgrade OSes; by and large wireless 'just works' in these cases with Windows. The pre-install is not a special case here.
You are absolutely correct - I have no idea what ETV was like in the 70s, 80s and early 90s. Was it less government controlled during the Derg? Or is this post-1991 era?
So how do we and that Ethiopian shaman differ?

Paper! Seriously, this was 1960? Even ancient Sumerians were using paper to do math. I don't understand why in 1960 anyone would seriously still be doing math with holes and rocks.
Thanks for this. Quite incredibly valuable comment. This is why i love HN.
I've been using UX on Mac and Linux for a few months – love the tabs in the titlebar on Mac – and rarely have problems. A few extensions aren't compatible, and occasionally a build is unstable, so I also have Firefox (stable) and Aurora installed. I just restart into a (more) stable release if there is an issue. They all use the same profile, so settings and tabs are shared. Lazy-loading for tabs make restarting not much of an issue, even with a couple dozen tabs open.
Terms of Reference & Vectoralist Transgressions
While true this phenomenon isn't recent. Herman and Chomsky wrote about it in 1988 and discussed examples going back at least to the 1960s.
Building a business around open source. What works, and what doesn't.
Perhaps it is out of date; they did try to charge me $80 to remove crap in March 2011 (so, 2.5 years ago). It was from the online store - but I believe the brick and mortar stores already existed.
And I'd undercut you by selling at the older price, increasing my total profits... Except that I'd lose market too, because somebody would use the newly achieved scale to save costs and undercut me too.

Distributing money does not make capitalism go away.
Have Glenn Greenwald "leak" some information discussed by Frontline or Bill Moyer and a lot of people will suddenly discover it for the first time.
> assuming vectorization doesn't come into play.

Now that 256 bit AVX registers that process 4 numbers in one go, even when one uses 64bit floats (and 8 with 32bit floats), vectorization more and more comes into play.

Using 64bit floats with 128bit SSE registers, it was kinda possible to ignore the vectorization, as it was less than 2x speedup. But no more.
Not at all. You can have a single-member district system using a different voting system, most of which are better than plurality (first-past-the-post). And you can have a multi-member district system using the multi-winner equivalent of first-past-the-post (effectively first-N-past-the-post), rather than some better system.
Open source is definitely the most amazing philosophy on software development.

Recently a guy at Facebook recruiting staff contacted me by email for a position inside the company saying that they liked what I've been building and publishing as open source.

I'd highly recommend to everyone that contributes with open source to attach their github/bitbucket/googlecode/etc accounts on their resumes.

I'm doing exactly that on my linkedin summary and it helped me a lot to introduce myself. http://www.linkedin.com/pub/juan-manuel-garc%C3%ADa/29/4a5/2...
> "Ordinary" people going to Russia ... having details ... leaked

This is case everywhere. Do you think NSA will just delete their databases? It is just question when all this data will get connected with Visa Applications, IRS and others. In 10 years DMV will be sending speeding tickets based on data -mining.

I can even imagine petabyte leak when all this data will just appear on bittorrent.
Oh, please. The US has a well documented history of spying on and infiltrating political organizations domestically and internationally ranging back to the labor movement of the mid 1800's (at least) and up to modern day, as well as suppressing dissent with methods ranging from assassinations and economic destabilization to assisting coups d'etat and invasions. Why should we believe that has stopped?

I don't know about the extent of spying to deal with political dissent in the EU, but I know quite a few people who were subjected to rather intense illegal surveillance in Norway, that was often clearly intended to intimidate (when top level people in the security services start conversations with you on the street about the argument you had with your wife, in your living room, the other night, it is pretty clear what the purpose is). When this monitoring was rolled up, it eventually was revealed that the leader of the parliamentary commission investigating the illegal surveillance had been put under illegal surveillance while he was investigating the illegal surveillance...

Given that this level of surveillance was happening in Norway relatively recently, I find it highly improbably that there's no extensive politically motivated spying in other European countries too, to this day, whether legal or illegal.

There is difference - sure. It is not politically acceptable to be seen to interfere with political parties at home in Europe or the US, so there may be less blatant interference these days, other than with fringe groups that are easier to find ways to label that makes them tolerable targets.
This post is spam.
Online petition basic income EU
I would love it if the Olympic team issued a statement like so:

"Upon hearing of the Orwellian-like surveillance at the Olympic games in Russia, the US team has decided to boycott the games. However, we are not boycotting the games because of Russia's surveillance plans, but because several major world governments now consider ubiquitous surveillance acceptable in free and open societies, with out own government, the US government, leading the way. We will cease our boycott when the US government sets a moral and ethical example for the Russian government to cease its plans by canceling its dragnet surveillance programs of both US citizens and our brothers and sisters from around the world. We are asking our brothers and sisters in competition from Russia, China, England and any other country guilty of mass surveillance to join us in this effort. If this demonstration ends any significance of the Olympic games this year and into the indefinite future it will have been because our collective governments no longer should good faith towards the people of this World, and we will no longer see a reason to continue to compete atheletically on their behalf."
He fails to mention their musical backgrounds: John McCarthy played with the Beetles and Grace Hopper sang for Jefferson Airplane.
I understand that frustration, and in the past I considered going back to windows. The thing is, for me at least, when I have a problem on my linux box there is a vast community that seems eager to help. Usually someone else has had my problem and already outlined the fix. When I have problems with drivers on a windows machine the answer is almost always re-install windows. For me that is less then ideal.
I don't think peeep is a viable option

How long will Peeep keep my data?
Virtually forever. Nevertheless, we retain a right to remove content which has not been accessed for a month.
No, journalism is not simply printing controversial materials. It does require some amount of investigation and analysis.
IPhone Fingerprint scanner hacked again
This is the best seed app of the bunch, but still fell down in a few places when I tried it out...

Remember when starting a new web project meant opening a notepad and writing some HTML? Yeah, well I spent 4 hours diving into this boilerplate project yesterday and still haven't gotten it right for Angular development and deployment.
> buying someone's loan and tearing it up counts as a gift

Through 2013 forgiveness of the mortgage on the debtor's principal residence is not taxable. If the law is not extended, there will spring up an industry to do wash sales of property so that the capital loss can be taken at the same time as the forgiveness.
And I'm pretty sure everyone has now agreed $resource is pretty painful.
Generally, out-of-the-box Linux driver support is more complete that Windows. Printers, network cards, and other devices that require driver downloads to run on Windows just work on Linux.
How widespread were home VCRs in the UK in the 60s?
... and who could forget Tom Love's performances with the Beach Boys.
Journalist Michael Hastings dead after telling his friends that he has a big story on CIA director and he needs to lay low for a while as FBI is "onto him".

How about that western word?

None of those "putin journo killings" has never been proven to have any links to Putin. All these anti-Russian accusations are moral equivalents of people claiming that US government killed Michael Hastings.

So please - STFU.
...and besides this allows you to surf without google registering every fart of yours. Good idea.

Uh, also I suggest to everyone the "self-destructing cookies" extension. I think it's the best cookie solution so far: basically it deletes the cookies after a certain "grace period" unless they are into your white list. This means that (1) your session is forced to last only for slightly more than the time you are on the website (2) you don't stand out as tinfoil-hat (https://panopticlick.eff.org/)
Nice initiative. There's little need to clutter the code base with redundant dependency injection ceremony these days (tools do it just fine) so I filed a PR: https://github.com/mgechev/angularjs-style-guide/pull/6
Dribbble Teams Product Is Available
From Ruby To Erlang: An Experience Report
fwiw the address bar does most of what Chrome's omnibar does, out of the box. It's just a bit hidden because they include the search field by default.
Incredible idea, and great use of bootstrap. Surprised that Reddit doesn't have anything like this on their site.
It's less about "modern mindsets" and more about simple decision making heuristics. If you've got a stack of resumes for apparently competent candidates and 10 seconds of Google-fu turns up blog comments and OS code commits for most candidates with reasonably distinctive names and MugshotsOnline for another one, you're probably not going to invite the latter candidate in to explain their views on occasional recreational drug use.
I'll give another example of why this is important. Ubuntu decided to have a 'Mac style' global menu bar for all applications. Turns out that when Unity tries to display a menu bar for Firefox and encounters a lot of bookmarks, something goes wrong and the whole desktop freezes. Guess the designers/developers never considered someone with thousands of bookmarks?

<http://askubuntu.com/questions/88908/many-many-bookmarks-in-...
I'd really like to know where are those places that tried minimum basic income, and if they were unconditional (or if people did lose money by working).
Microsoft or Apple could get away with this, since their browsers are bundled. Google could get away with it on Android.

But on the desktop? Nope. In a world where most users don't know the difference between a search engine and a web browser, Chrome's success relies on the tech savvy (through first person usage and recommendations to friends).

Add this "feature", and roughly 100% of that marketing force gets redirected back to Firefox.
For those who don't really need a Mac (no last minute Adobe pixel/vector pushing front-end work nor Mac/iOS dev works needed) where can one find reliable info on 100% Ubuntu/general GNU/Linux distros compatibility?

In short where can I find info about awesome notebooks with 100% Ubuntu compatibility?
>which runs a sideline business in murdering inconveniently critical journalists

Not trying to defend Russian govt (which is without a doubt pretty sinister), but this 'journalist murdering' thing that pops up every time Westerners discuss Russian internal policy is a bit off the mark. The way you say it cues that all Russian media is pro-government and Russian citizens en masse are either brainwashed drones or impregnable oppositional free-thinkers. While in fact its only TV which is thoroughly controlled by the government. Russian press is pretty vocal and most of it is clearly critical of the United Russia party policy. More so Russian online press — I don't know a single popular online news outlet which isn't critical of United Russia (modestly or very much so). Sure there are a couple of high profile murder cases that may be linked to Russian govt, but list of murdered journalists found in wiki is in its entirety composed either of people died in 90s or people whose death may (or may not) be connected with provincial level oligarchs, especially on North Caucasus. So saying that murdering journalists is what Russian govt does is just not true. It is true that govt doesn't provide them with utmost security though.

Why do I even care? Because you guys could be more critical of real and serious United Russia's wrongdoings (like prosecution of a row of activists involved in protests of 2011-2), instead of reiterating on secondary matters like journalist murders (ostensibly committed by government) or gay rights.

I hope I will not have to change accounts after this post.
... or Larry Wall's collaboration with Pink Floyd, before going on the found Perl Jam.
Ask YC: What is our company going to make?
While working on YC application question "What is your company going to make?", I've got in a mess that makes me rewrite my answer every morning:

In our answer, is better to focus on the proposition value that our startup is generating for our users/customers or is also important describe how our algorithm works?

For example, if Google was a startup applying for YC, would they explain how the search algorithm works? Or a better answer would only describe how Google is the best search engine for users?
Student Entrepreneurs: If Peter Thiel Calls, Hang Up
Uhm... you people know that Russia has already been violating a whole bunch of human rights, quite publicly, right? (eg. LGBT rights, freedom of expression in general etc). This seems like the tip of a really evil iceberg. Sochi games deserve to be boycotted because Putin's politics are an antithesis to the olympic ideals (and this is quite tiny in comparison to what is happening there ...).
There are ways to do targeted advertising without tracking. For example, you could identify clusters and then have users' browsers do the lifting to determine what cluster they belong in.
As Society Changes, a Brighter Future for Devices on Planes
Malcolm Gladwell - Zeitgeist Americas 2013
See also the work of urlteam [1,2].

[1] http://urlte.am/

[2] http://archiveteam.org/?title=URLTeam
> If someone has screwed up the regulations so badly that this information intended for the public is not actually public, then of course that's where the problem is, but that seems unlikely to me. It would make for a very interesting news story, if true.

Healthcare.gov is covered in HN-popular libraries, software, and toolkits (like Bootstrap, jquery, and Drupal[1]), so the problem is apparently not that they just don't know any better.

It appears they went as far as they could with the latest and greatest tech. Someone somewhere along the chain of command failed to include a "provide any kind of useful information on the plans" provision in the design document. All signs point to this being either politics or negligence, not technology.

[1]I'm assuming on this one since WhiteHouse.gov has been covered in Drupal in the HTML and JS since the Obama administration took it over.
First, some counties publish special lists of, for instance, men attempting to or procuring prostitution services aka "johns". So there's probably a fair amount of shaming and threat they get from this. Police are known to threaten arrest because even if they drop all charges just going to jail (especially on a weekend) can be an unpleasant experience, and there's little blowback for them.

Second, if the police want to disappear people, they'll just not save that arrest record. The publishing of a log only is only useful for cases where the police decide to "disappear" you after they've arrested and processed the subject. Even then they could release someone, document it, then pick them up around the corner for "disappearing".
You don't have permission to access /2013/10/01/ubuntu-pre-installed-and-in-retail-worldwide/ on this server.
WTF!
In my country, the first thing that many people do after buying a laptop with Ubuntu pre-installed is formatting the drive and install a pirated Windows copy.
I didn't arrive at it, it's a well-known industry figure, I'm not sure where I heard it first. (I live in Los Angeles and lived in Hollywood for years, working mostly on the film side, but I know a lot of people in TV, too.)

Here's an article for consumers on unbundling[1] I found after one Google search that says that ESPN alone receives $7.2 billion per year from US cable companies, which sounds about right to me. (They also earn money for ads, I don't know if any of that is kicked back to the cable companies. I doubt it...)

It shouldn't be surprising even if you crunch the numbers yourself. There's ~100 million cable subscribers, and the average combined bill (Internet/Cable/Phone) was $128/month in 2011.[2] So that's $153.6 billion per year. It's not hard to imagine that ~20% of that goes to the people making the content that's playing on cable. If anything, it'd be surprising if it were lower than that.

[1] http://money.cnn.com/2013/08/02/technology/cable-a-la-carte/...

[2] http://online.wsj.com/article/SB1000142405297020347910457712...
Googling someone is being creepy? Please.
Agreed. No real content, just two 'buy ssl certificate' links.
Is the Angular community moving towards each controller having its own module? A controller per file but all controllers in one module doesn't work so well.
Best course of action is to find a notebook without dual video cards (optimus), and go from there.

Find something you like, Google if someone has posted information about the laptop and go from there.

Ubuntu on laptops now adays has pretty damn good compatibility if it's not brand new - but the kernel quickly fixes that if you use a kernel mainline version.
The DVR is establishing a connection with the cable provider so that it can communicate the details of your activity back to them. This can take several seconds due to load or inadequate resources on the server side.
Thankfully, the notion that Hastings was somehow killed by having his car remote-controlled by the CIA has largely become the province of Infowars.com.

When the Russian government has someone killed, they don't die in a mysterious accident. They're gunned down, when they're lucky. When they're not, they die an agonizing death after being subtly and fatally poisoned by radioactive isotopes.
Duh, it stopped when organic growth stopped. But we were stupid to have believed it in the first place.

Now they are desperate: ads everywhere, penalties everywhere (makes you advertise to replace lost traffic) and so on. They still make north of 95% of their income on ads with all their supposed innovation. I don't trust them at all. On anything. I wonder what Google Search "Quality" has in store for 2013th fourth quarter.
Your server as a function [pdf]
I wasn't. I was making the point that it's important to realize that it is a question of freedom even if you don't regard it as one that should be had. There are those who don't believe Snowden is fighting for justified freedoms and that his alleged treachery is worse than facilitating drug trafficking.
As far as i'm concerned the whole libertarian crusader thing was bullshit.
It is a business so the proposition value for users is more important. Algorithm is pretty much irrelevant for users and it could easily change over time.
After reading the article, I fail to see how these are not confined to one device. basically, the article suggests that they'll add a random unique ID to the browsers' identification (I assume they're talking about the user agent). How would this spread across devices?
I'm not sure this meets all your criteria, but I'm glad Dell is doing it:

http://www.dell.com/us/business/p/xps-13-linux/pd
Mozilla Voices
Icon Tester 2 - Icon Test Tool for Designer(iPhone,iPad/iOS5~7)