skysight-inc/HackerNews huggingface dataset:
Here is a link to a related trial in South Carolina currently recruiting participants to examine a role for CD47 in myeloma. It is not a trial using the antibody cited in the OP's link, but a study to examine if targeting CD47 (and some other potential targets) makes sense in a human context, rather than just in a mouse.
Yeah, I would say customer service is one of the major shortcomings of Google right now. I would think with their transition to producing and selling physical products that would be something they have to improve on soon.
You're discounting the second half of the sentence you quoted:

> but barring that, selfish as it may sound, if I could have substituted all the plain-clothes promoters for traditional booth babes, I would have done it in a heartbeat.

Of course, progress isn't a panacea, but I'd take progress over the "old days," myself. I've personally seen the number of confidently technical women at conferences increase year over year for the past decade (please note, I'm not saying that the status quo is optimal, just that, in my experience, there _has_ been progress).

Moreover, the _title_ of the piece concludes with "Thanks But You sort of Made It Worse" which contradicts what you said.
Here's a fairly recent end-to-end ServiceStack vs WebApi benchmark:
https://twitter.com/anilmujagic/status/272544925478973440

ServiceStack 9615ms
WebApi 30607ms

GitHub project for benchmarks used: https://github.com/anilmujagic/ServiceBenchmark
He's actually a really nice person. He helped me out (to him I was just some stranger on the phone) when I was trying to decide what to do with my career when I was in NYC.

Zed Shaw is probably one the best people you can know in the developer community, a very good guy.

Your sensationalism based on some of the stuff he says on Twitter and Blogs is amusing though.
It's complicated, and I wouldn't rule out simple disgust at obvious rent seeking behaviour, but yes even at 13 million a year and going up by 15% per annum I'm not sure the money works out on saved licences alone.

I assume that, like many of their more audacious bets, the idea is to remove a pointless tax on innovation on the web and including the potential for interference in their business models going forward.

Just like Apple did back in 2002:

http://www.bizjournals.com/boston/blog/mass-high-tech/2002/0...
I think the issue is what it takes to convince a person you are technical. As a man, if I join a conversation while other people are talking technical, I will generally be assumed to be technical. I can easily imagine women not having the "technical" bit default to true.

You highlight a real issue, though. Given the percentages, if a technical conference has a large percentage of non-technical attendees, it is likely women will be seen to have the "technical" bit off. Certainly more women in tech would fix it, but that isn't the solution, because we won't get more women in tech if they continually feel uncomfortable.

Conference organizers could do more. Instead of "attendee"- and "vendor"-type badges, they could have more detailed badges that are noticeable quickly and easily. I know I would appreciate knowing at a glance, in any technical conference, how technical the person I'm talking to is. Saves us time talking past each other or covering ground we both already know.
It's fun to watch people dismiss a strong statistical signal when it disagrees with their prior beliefs
I'm not so sure about that. Even with recursion turned off, the server still responds with an error packet. While the error pack is small compared to an actual answer, hit enough DNS servers (authoritative or not) and you can still generate quite a bit of traffic.
Like everything else, there are smart and stupid ways of going about this legitimate objective. This is an example of the latter.
Absolutely not as assuming causation implies you know the directionality of the relationship. Cancer correlates pretty well with old age but you'd be pretty silly to assume that it causes old age.
Three flavors of freemium
In that sense the marriage is a capstone, but there is no difference between that couple and a couple that got married right away and have been together for 8 years.

I always laugh when I hear this. People also say "Marriage is just a piece of paper."

My answer is "tell that to judge when you want to get out of a marriage."

Does a marriage certificate make your relationship more serious? No. Are you entering into a legal contract when you get married? Yes.
Personally I think Amazon have just purchased this site for the data.

Goodreads has a fairly reasonable recommendations engine based on the book collections people have inputted into the site, so I'd imagine that information might be very interesting for Amazon to capitalise on.
Jaguars, maybe!
The researcher's explanation of his research: http://rocs.northwestern.edu/research/wgstory.html

Edit: this link doesn't explain this specific set of maps, but it does explain a little about how he got the idea of using wheresgeorge.com and what it allowed him to do (as of ~2009).
Personally, I'm glad you did. I'm a male engineer, but there are two women engineers in my family (mom and sister). They always bring up these situations to me that few seem to notice. And honestly its really difficult for them at times to be in this industry. More discussion is good.
I just want to say thanks to everyone who took the time to check out the article as well as all those who took additional time to leave a comment both here on Hacker News or on the blog itself. This has definitely been a humbling experience and I hope to keep you all informed along the way. If you're interested in getting updated on Project Morph, I've posted an email sign-up form on ProjectMorph.com. Thanks again for all the kind words and support.
HN: I will buy your side/weekend project for $2,500.  Top 3 Apps win.
I've noticed some incredible weekend projects and side projects from talented HN hackers.

I'll pick the best 3 websites/apps from HN and pay the winners $2,500 each - no strings attached. Why? Because there's probably a bunch of hackers out there who don't have the time to fully develop, but still want to see it grow.

If you have a project that you'd like to offload and sell, include a link in this thread and a brief description of what the app does. Mobile apps are ok too.

Just like this

My app is www._______.com; it provides SAAS subscription services for marketing.

____________

So, if you have a weekend project, side app, or just part-time project app - list it below! Top 3 apps chosen will win.
According to the owner of the site, Kindle integration will be a top priority

"2. Our members have been asking us to bring the Goodreads experience to an e-reader for a long time. Now we're looking forward to bringing Goodreads to the most popular e-reader in the world, Kindle, and further reinventing what reading can be."

http://www.goodreads.com/blog/show/413-exciting-news-about-g...
Agreed, but it's hard to know in advance what features will be useful, and once a language is established, it's hard to remove less-used features without breaking existing code.
Thank you for succinctly stating what I used 9,000 words above to say. Sure, thanks to discretely-dressed marketing ladies, the author's life has become "harder than it used to be." She can no longer count on being on oddity. It was great while it lasted. Now, she can learn to introduce herself just like everyone else...
The causation could easily be backwards. Who wants to marry a depressed, unsatisfied drinker?

> Isn't it generally sound to assume causation until the position can be falsified?

Not really, no. Would you assume causation in the case of cereal consumption typically increasing 30% on the first Tuesday after a heavy rainfall? There are many similarly insane correlations that you wouldn't be so quick to assume causation about. It's biased to assume causation (based solely on statistics) when you want it to make intuitive sense.
I'm working on a curriculum for basic programming in R, hopefully that will eventually help outline what everyone should know about R, regardless of what they use it for.
Google could send VP8 to iOS today if they wanted, YouTube is a Google app now, not an Apple app with Google content. They send vp8 to the Nintendo Wii app.
Does Summly Run Afoul of Copyright Law?
It's the Game Developer Conference. Marketing and sales are sort of baked into the very idea of a major conference, these days. It may not be ideal, but it's reality.
> Show me a counterexample, that's all I ask. I'd give all the rhetoric in the world for a single damned counterexample of a program format that's lasted since the 80s. That's what's at stake.

ELF was defined in the late 80s/early 90s as part of SVR4. COFF was defined as part of SVR3. Both still exist today.

The JVM bytecode was defined in 1995 and has been evolved compatibly.

I'm curious, though. Do you require the same longevity of web formats that were defined in the 90s? Things have changed quite a bit, and attempting to browse the modern web with a 90s browser is futile.

Given that, I don't really understand what you're arguing for.

> Regardless of my opinion of NaCl, this is stuff that should be getting defined slowly and in the open by bearded old men that have spent their lives in glacial, trusted industries like telecoms, or just about any other mature technology industry.

Us 'bearded old men' aren't on the web, and its only improvements like SPDY, WebSockets, and NaCL that have made me the slightest bit interested in the web as an application platform.
Wow, you've distorted the situation considerably.

These saleswomens' employers are giving them dress-code guidelines already - " telling OTHER women how they must dress". That was true with "booth babe" dress and presently. The woman's blog post was clearly addressed to GDC which seems to have set the tone for the companies at the booth who hired their saleswomen/demonstrators. There's no situation of a woman commenting about another woman's clothing choice on, say, her day off.
> That seems backward to me--when you've already figured out what to make, and the hard part is producing mass quantities of it--isn't that what patents are designed to protect?

The archetype of what a patent is designed to protect is something like a drug formula. Manufacturing lots of drugs is easy--figuring out what chemical to manufacture is the hard part. That is both hard, expensive, and easy to reverse-engineer.
Rasmus has clearly stated that PHP's ugliness is a feature. http://osdir.com/ml/php.devel/2002-10/msg00704.html

He freely admits that he is a crappy programmer who can't write languages. His goal was to re-use code because he hated (hates) programming.

That doesn't really explain why contributors perpetuate the atrocity, but understand that PHP is the way it is based on a set of priorities that many of us do not value.
As a 31 year old male, here is my message to tech companies with products to sell:

If you have "booth babes" (I think she did a great job in the article of defining what that term means), I'm not going to buy your product. I hate it and always have. Its trashy and demeaning, and I resent being grouped into the lowest common denominator when I go to view a product I actually care about. As demeaning as it is to women, I think a lot of men would agree that its demeaning to be treated like a dog who can be baited with a doggy treat.

If you have a good product, you don't need to lure in knuckle draggers who let themselves be led around by their reproductive instincts.
Buttons, badges that are different colors, or find a sponsor to give t-shirts to the technical people for each day of the show? The propeller beanie isn't really something I picture many of us wearing (well ... until it advances to the point we can use it as a personal transportation device), but anything to differentiate the real techies is good.

I should also point out that meaningful conversations can happen between the marketeer and techies, but what do we do with the non-exibitor PHBs that attend.
I agree.

As long as the debian infrastructure is fully automated (it is), the actual time delay from pgsql's announcement to it hitting debian servers would be only an hour or so.
Well, you could say "women with body types that men are more likely to pay attention to" or as they are commonly known "models".

Trying to get people to deprogram their own biology at a very deep level is probably going to be a losing battle.
Facebook Actions Are Coming to Status Updates
Yah, sorry, don't like it one bit. I don't understand how you could think that works better for consumers than OS X or Windows. I do think the desktop metaphor is on its way out, though (see iOS and Win8)
Hacker News: your go-to site for Gender Politics! Bring your grievance to Hacker News, and let our expert commentators put your resentments under the microscope. We've already analyzed dozens of fascinating complaints just like yours, and our appetite for endless debate grows day by day!
Right, I agree with you. Its not that the strategy won't save any memory. But it won't save any memory allocations because the list still makes them. The number of allocations can put pressure on a garbage collector just as much as large allocations. Maybe even more with fragmentation and the like.

In C you explicitly choose stack vs heap allocation. In go, the runtime does this for you. I had a couple of situations where, after profiling, most of my CPU time was going to heap memory allocations. Using the strategy on slide 13 probably would have helped some to reduce the size of the allocation, but in my case only by a few bytes. Using a fixed-size slice that held references to objects made a big different in performance.

In regards to slide 13 it just seems funny to "recycle" memory by forcing a whole new allocate/deallocate cycle.
oh, no. I was not saying that I have such an impression. I sometimes wrongly use "I did not say" as "I don't think" as a habit, literal translation from Russian where it does not have critical connotation.

I fixed the comment above.
Andrenid, we're also using Zendesk. If you don't mind me asking how many agents do you have?
> even if they haven't produced offspring that will labor in the economy while the retired generation lives off their production.

This is the unfortunate fallacy that most make when looking to social security and its apparent dwindling in funding. You are insinuating that social services must come from taxation of individual labor, whereas our economy has successfully and continuously been moving towards a more capital based economy.

In short, where will the money come to fund future social services? More from capital, less from the individual labor of your children.

"But America as a whole won’t have gotten poorer: the money is still there to support the programs, it’s just coming in the form of capital rather than labor income. There would be no problem, at least in economic terms, in continuing the programs by adding revenue from general taxation, maybe even from dedicated taxes on capital income." - Paul Krugman
http://krugman.blogs.nytimes.com/2012/12/28/policy-implicati...
I agree that it makes a ton of sense for both companies, but how they integrate it is going to be very important. My wife and I don't use a number of Kindle features (including the current built in review feature) in part because we share our Amazon account. But, I am a big GoodReads user.

If Goodreads just gets attached on a per device basis (like Twitter), then it's no problem, but if it gets integrated with the Amazon account itself (as some people seem to be suggesting) then I don't see how we (and many others like us) could use it.
This is also my experience: I was 22, she was 19 (married 10 years now). We finished school (3 BS, 1 MS, and a PhD between the two of us) and worked before having kids. I feel like we got married before we were each too stubborn and set in our ways to change. We met in the middle and grew into a single individual, greater than the sum of its parts. My (non-scientific) feeling is that in general, those I know who waited to get married had a more difficult time assuming a new identity that incorporates another individual.
I'm not looking forward to this. The best community was just bought by the company that killed text-to-speech in their product in favour of making hundred of millions on audiobooks. Welcome to your new garden prison, online book community. Enjoy the complimentary bookmarks.
I'm more impressed by graphs like this: http://c3headlines.typepad.com/.a/6a010536b58035970c0134849d...

Climate changes naturally a whole lot more than we are comfortable with.
It´s very strange that Memphis is over one of the boundaries. It's the only big named city over a border.

I looked in the map, because I don't know the zone. (I hope I readed the map correctly.)

Memphis is in south west corner of Tennessee state but the city continues informally but smoothly to the south in the Mississippi state. On the west side the city is the Mississippi river, and crossing the river is the Arkansas state. This area has much more green fields and few building zones.

So Memphis is not on the border, it is just right next to the east side of that border.

Map: http://maps.google.com/maps?q=memphis&hl=en&ll=35.01...
Anyone else find it interesting that the author is from Liberty University?
> "You’ll get free, unlimited same-day delivery for six months. That’s six months of having toilet paper delivered for free"

Ok, but delivered by regular human in regular car ? No thanks. I want delivery by unmanned google-cars. For that, I'll even pay premium shipping.
This kind of capability (exporting and integrating kindle data) already exist. Take a looks at http://amazd.com/ahmad/book for an example.
How is this a good thing for readers and other book retailers ? Will we still be able see links to buy books from a number of different retailers such as B&N or Indigo ? I doubt it.
Are algorithms invented or discovered? It's a curious question regardless of this situation.
wow, that's a pretty shitty attitude you've got there. You don't need to be sarcastic and condescending to disagree with me.

the point that I was trying to make which you seem to have completely misunderstood is that it doesn't seems necessary to create an account to use this application; I sign up for new things all the time but I don't think it's necessary for me in this case and feels like a barrier to entry. The OP asked for feedback, and I provided it based on my opinion on how I personally would use the service.
Facebook's Mark Zuckerberg Faces $1 Billion Tax Bill
I think you may misunderstand Vert.x's polyglot features:

While vert.x supports many programming languages, all of these are run on the JVM runtime. This means when you use the ruby vert.x API, you're using JRuby; likewise with Javascript run through Rhino, Python through Jython, and Groovy/Scala run through their own interpreter/compilers.

That said, it would definitely be interesting to see the performance implications of using one of those languages and vert.x on the JVM.
You guys should feel bad about generating such awful benchmarks.

How the hell can you compare accessing a MySQL database to accessing a MongoDB database?

Its like comparing apples to piles of poop.

Also when you're testing things like Django in web requests, you're testing gunicorn, not Django.
First ten participants get a free "My feelings for dongles are modern and nuanced" t-shirt.
Actually, it might be through self driving cars. Probably come with a regular human, though. See: http://m.digitaltrends.com/lifestyle/google-plans-to-use-sel...
Amazon Acquires Goodreads
I don't really see the big advantage to << over named functions here. Compare:

cout << string << " and " << otherstring << endl;

cout.write(string).write(" and ").write(otherstring).write(endl);

It's about as readable to me. To me, operator overloading is good when the meaning is already obvious because of shared context that everybody has. That's not the case when co-opting << for stream operators.
The Fallacy of "Faster Horses"
I'm sorry, the full name is 'Cairo-Dock' (http://www.glx-dock.org/)
Is this resuming http://ryanhoover.me/post/43986871442/email-first-startups ?

It's getting noisy in here.

Edit: Here's the discussion: https://news.ycombinator.com/item?id=5279590
Golf Equipment Directly From Manufacturer
Now the lawyers and judges just need to realise that "mathematical" != "numeric" and we're home free.
Building Vim
Assange prosecutor quits
I'm really excited to see them focusing on security issues, which is the main reason I used Django over a DIY framework. The faster release cycle is also good to hear about!
I work at SugarCRM and we use our own product to handle cases. I do know that there is Zendesk integration which has been quite popular too (assuming you might also be thinking about CRM; just throwing that out there) http://www.zendesk.com/product/features/sugarcrm
I'm quite aware of that, thanks. View that sentence as a verbal experiment whilst trying to generalize around the hornet's nest my mind has accrued around the phrase "booth babes."
Could you mark your edits in the article as such? It's making the discussion here difficult to follow as people are referring to outdated versions.
The Pleasures and Perils of Less Popular Linux Distros
> I was referring to individual-level retirement planning. That is, does it make sense for me to invest in one or more children based on the expectation that those children will directly help me (financially and otherwise) during retirement?

I understand. I was pointing out what impact our national retirement policies had on individual incentives and how that translated into group incentives.

> However, as far as I know, it was always a program whose ethical justification was that you get back what you put in, plus some return. Whether or not you have children is irrelevant.

That's an abstraction. It doesn't matter if you only "take out" what you "put in." At the end of that day, somebody's kids are producing what you take out. Any retired generation inherently depends on the production of the working generation, and for a generation to retire, there has to be a working generation to take their place, which means having kids. Social security versus investing versus whatever is just a way of accounting for that basic transaction.

> Furthermore, if we presume that the ethical justification for social security is that one's children are going to be productive members of society, how can we adjust for unproductive children?

I'm speak at the group level. It's fairly irrelevant whether one person does or does not have kids, so it's useless to try and account for that at the level of Social Security. However, Social Security as an institution reduces the incentive for everyone to have kids, because they can just depend on the production of the kids of people who did. It's a free-rider problem.

> If social security is an intergenerational contract that involves a transfer of wealth from the young to the old, then it's an unjust Ponzi scheme that will collapse as soon as demographic trends are no longer able to sustain it.

It's a Ponzi scheme, but what makes it unjust? It's the circle of life, man. Your parents took care of you, and at the other end of the cycle you take care of them. The really useful insight is that it's a Ponzi scheme that's unavoidable, at least with existing technology. By and large, the human life is bookended by periods in which people are not self-sufficient and not able to produce. No matter how you abstract the underlying intergenerational transaction, you can't get away from it. We're engaging in the same intergenerational transaction people did tens of thousands of years ago--we just have a different, fancier way of accounting.
Many people should apply this to their work. But I think it also applies to life goals. Too often people don't reflect about what they really want and how they might find a path to get there.