skysight-inc/HackerNews huggingface dataset:
"These data were first published in 1924. Why has such a major medical finding, published in high-impact peer-reviewed journals, faded into obscurity?"

Possibly because the reported research results were not replicated? I wish I had the citation at hand for a finding that 50 percent or more of all medical research findings published in top peer-reviewed journals end up not being replicated. But perhaps that finding can be found in one of the sources cited in Peter Norvig's excellent article about analyzing scientific research papers,

http://norvig.com/experiment-design.html

which I recommend readers of this thread check as they consider the claims made in the submitted blog post.

After edit: Another problem at the practical level is that it may very well be that a diet optimal for recalcification of teeth (there is no controversy at all that teeth can recalcify throughout life, that's the point of fluoride treatments, but the question is by how much) may not be optimal for cardiovascular health or some other aspect of your health that is important to you. The way human evolution works is that all of your body parts are fitted by haphazard adaptation from ancestral patterns using available materials in an environment of biochemical trade-offs, and it may be a better trade-off to have teeth that decay after reproductive age and a heart that keeps beating longer than to have teeth that never need to have cavities filled. That would have to be the subject of further research, to see which diet is optimal overall. (Yes, I am aware that some research tends to show that good dental hygiene contributes to good cardiovascular health, with the hypothesized mechanism being that infected gums allow bacteria to enter the bloodstream and cause inflammation of the heart's blood vessels.)
Roller Coaster Simulation of the Stock Market on the iPhone
Rob the poor when they need loans, then snap up all the properties in distress and rent them out with high technical proficiency. Hmmm, if you don't see the serious problems here you should be asking yourself some really tough questions about where the state of your personal ethics is.
YC is international.
Cloudburst is the RMAP genetic search algorithm - and it is baked in already.
Amazon has done it more than twice. They do it consistently and across their three core businesses.
There's classes for this stuff at Stanford!?

Then what do you do with your free time?
I'm not being sarcastic. I was a nerd activist for a while and there really is nothing that protects them from this.
While you and I may be financially educated and well versed, many people are not. The only reason credit card companies make money is because there are people who don't understand how credit card companies work and make only minimum payments.

Not to mention there are cultural and demographical biases against banks and credit cards. When I was in China I knew many people who did not trust banks. They either did not want how much banks/government to really know how much money they had or weren't sure their interests would be looked after if something were to happen.
That's fine - I wouldn't move either if I was lucky enough to have a family. But for people who put their company above all else (not recommended, having done so), it's an irrational decision to stay if you want funding. Everyone here bemoans the terrible funding environment. We can't even get a YC ripoff here.
I believe the implication is that "If it's patented by someone else, Google may have to pay if it comes out that they are using this technique"
Flight to Quality in VC Land
This guy might be the best guy in the world but payday loans are predatory lending and regardless of the situation, puts people in a worse spot than they were before.

Depending on the situation, they can charge over 1,000% interest. If payday loans were to charge 30% interest they'd still be able to cover the people that wouldn't pay.

It's a dumb saying but "don't be evil" springs to mind. Taking money off of the backs of the people that can least afford it isn't capitalism, it's greed.
Even though his argument seems optimistic, hopefully he can reduce some of the crazy awards and "lost revenue" or perhaps expose some of the inadequacies in linking actual filesharing to a particular person.
But their move to Scala meant the Fail Whale went away and their investors were happy enough to sink many more millions into the company. Would it be possible to run a high-volume messaging system in Ruby? Perhaps. But why fuck around when the people bankrolling your company are getting angry?
One of the main characters in The Merchant of Venice is Shylock, the Jewish moneylender. That's where Goldstein's Jewishness comes in. PostOnce was just noting the coincidence of having read this article after some Shakespeare. It's not remotely anti-Semitic; calm down.
SandBot - Robot for Traveling on Sand
Anybody else think that TJ Rogers Article is what is exactly happening today?

Wow, just wow. Why isn't TJ Rogers the Chief Officer on finances to the president?
I would posit that the diet presented in the article not only contributes to good dental health but also would contribute to good cardiovascular health.

The diet is low on refined carbohydrates (which lead to heart disease http://www.hsph.harvard.edu/nutritionsource/what-should-you-...) and rich in vitamins.
But Twitter isn't a normal website and Ruby was the reason why it kept failing. That doesn't mean your website will fail because of Ruby, but Twitter had too much background messaging work for Ruby to keep up with. The fact that simply replacing the code with Scala made huge improvements should demonstrate that fact. They didn't change what was being done, just what language was doing it.
Conceptual Strategies for Marketing Your Internet Company
Un-Trainable Attributes of Wildly Successful People
I just mean in a general sense: e-commerce and now the cloud.
As someone who loves design (and is not very good at it): it's interesting how simple the iPhone appears after seeing it - but to design something like it before seeing it is something else...

http://appleiphone.blogspot.com/

http://www.mobilegadgetnews.com/index.php?showtopic=11533
Grading Your Software Business Idea
This is funny, I actually had to do this.

I had a flash app hard coded to look for a particular .php file. It would have been a PITA to get the source for that, so... just figure out what it expects, and Rails route it. This approach is handy to know about.
I will be toothless before I give up bread.
Freelancers are not free
What I don't understand is that no one addresses the bacterial component of cavities. I just had some work done and my dentist clearly stated that cavities are caused by bacteria eating through the enamel. I get that poor diet contributes to calcium loss and so the body will re-strengthen teeth given improved nutrition, however this will not do anything to address the bacterial infection problem.
Actually a lot of fund managers invest in their own fund, many heavily. A lot of fund investors look for that.
The problem with freelancers is that they don't see their situation as exploitation so they can stay. One of the best way to get out of the freelancer situation is by creating a company. Then, the way a customer view yourself is really different. They know they are talking to someone that wants to make it bigger. Even if people around you say that it's too expensive and unecessary, it will change your relation with your customers and the way you see yourself.
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No. Not in a million years.

Anything that requires typing obscenely cryptic commands in the right order and getting very variable-quality feedback about the results is not user friendly by any definiton let alone newbie friendly. Just because you and I know how to hack the command line doesn't make it easy or good and we shouldn't kid ourselves.
In other news, US could see large anti-recession next year. The press has no idea what the market is going to do.
/agree the bottleneck for any website is ALWAYS the database, never the language. If you have requests that are bottlenecking at the language, nothing is going to solve that.
There's a reasonable amount of evidence that following (generally) a diet as outlined in the article would be beneficial to one's health across the spectrum. Google 'paleolithic diet' (alternative spelling, 'palaeolithic') for further information.
"Seems to me to be an understandable principle that it's
okay to consume and share nonrivalrous [sic] good which are available on the net for free."

I keep hearing this argument that the owner of the original file does not lose anything if you copy it. Well, the owner of a banknote does not lose anything either if you make 10000 copies of it.

Both files and money have an abstract value, and copying dilutes the value, hence copying is forbidden.
All I want is IRC compatibility.
A JavaScript Curiosity Regarding addEventListener
This article added nothing to my *Nix knowledge. It even gave bad advice to 'cat' a file and pipe it to 'grep' (which was also mentioned in the comments).
but sadly I can't see it!

added mine to mine. :)
Different URL. Here's the original posting: http://news.ycombinator.com/item?id=433456

It points at semyon.com, which now redirects to blogspot.

Definitely worth reading if you missed it the first time!
Vitamin D = the most common vitamin that doctors themselves actually take: http://www.cnn.com/2008/HEALTH/diet.fitness/11/13/ep.vitamin...
I hope you will excuse me pitching my own product, but it's exactly relevant to this thread.

'How to Hire a Good Technical Salesman manual' by Robert Seviour

http://seviourbooks.com/how-to-hire-a-good-technical-salesma...
Let's do a little research. The trader in the article, David Shorr, lists himself as a CashNetUSA founder on linkedin.

http://www.linkedin.com/ppl/webprofile?action=vmi&id=659...

He also appears as a manager in some of the SEC documentation.

http://searchwww.sec.gov/EDGARFSClient/jsp/EDGAR_Query_Resul...

David Shorr is 45 according to pipl.com

While Mr. Goldstein was a founder, he wasn't the only founder, and he had some more senior, connected talent to help him.
Sure, it's open to international applications, but it's still physically in the USA. The UK Government &c want companies to start up here, not seek exotic shores for support as we currently have to do if we want to get all the benefits of YC.
The sorts of talks to entrepreneurship clubs etc are more the small, focused group of people than big recorded lecture sort anyway. Though I suppose it depends on the club.
Let's solve the DRM problem right now and stop selling games that aren't tied to digital distribution systems like Valve's steam or the upcoming On-Live distribution model.

Not only does the publisher/developer get great control over their distribution, but the consumer actually wins as well by being able to access their games just by logging in to their account on any box. Not to mention the community aspects that come along with these systems.

Its a no brainer especially when the internet becomes even more ubiquitous.
FWIW, I really love my Acer Aspire One which I've been using for 6 months or so. I'm not an active Hulu user but I did just give it a try and watched about 5 minutes of Family Guy without incident; your mileage may vary.

Originally, I picked it up just to satisfy my inner geek and thought it might be good for my 7 year old daughter. On that score, it sucks because educational/kids games just can't handle the small screen. I can play a mean game of desktop tower defense or a few goodoldgames.com games, but as a gaming machine, you'll be disappointed.

I use it mostly for surfing the web, skyping, and watching video while traveling, and it works great. I bought a 3rd party battery off ebay and can literally run it for 6 hours watching video which covers most of the travel I've had to do. When around the house, I tend to use it more than our other laptop; it's just so light and easy to carry from room to room, I prefer it for short stints of web surfing.

It's also fairly hackable; I have it running linux, winxp, and MacOS (although I did replace the wireless card to get it working properly).

My wife is going to give it a go for a couple weeks to see if she can effectively use it to replace her laptop at work. With the slightly smaller keyboard and less than stellar mouse, I don't think it would be good for 8 hours of office work alone, but when connected to a monitor, keyboard, and mouse, it might work for her and you can't beat how much lighter it is to lug around.

I think the sweet spot of the market is teens and college students who don't care about video gaming. With it's long battery life and small size, it would be awesome for taking notes in class, and be good enough in a dorm room with an external monitor and keyboard, for most other non-gaming use.

You also can't beat the price albeit for $200 more or so, you can get a pretty decent laptop these days (or if you are like me and buy extra junk like a battery, external dvd reader, and a wifi card, it's almost a wash).
By "hacker" I mean someone who has the compulsive curiosity for programming that some of you seem to have. And by "intimidating" I mean they seem like they might be much better programmers than me. (Hence virtual experience is just as good an indicator as real-world experience.)
In my life, I have eaten very little refined/added sugar (i.e. very rarely do I eat such things). Aged 30 I have no fillings: the only dental work I have had done was having my teeth straightened and having eight of them removed (yes eight, though not all at once) that didn't fit in my mouth (I have big teeth). When I was a child, my dental hygiene wasn't always very good.

A single data point doesn't tell you anything. But there it is, anyway.
Your comment is the only reason I'm not flagging that article. It's not spam, it's just so very wrong.
There's classes for many many things at Stanford as there are at many other schools. Internet technologies etc happen to be among them and they happen to be offered under the CS department (which is probably the most appropriate one). The CS193x change from year to year I think, I remember there was a CS193j (programming in java) at one point but it seems to be gone now.

They are not required courses for the CS degree. IIRC I don't think they can even count toward any of the CS degree requirements themselves. You do get credit for them though and you need a certain number of credits to graduate regardless of major.

So basically you take them if you're interested in them and would prefer to learn about them in a classroom environment.
What is html encryption anyways? obfuscation?
There is a lot more to this story, but briefly, the pH of the mouth. The more acidic and the longer it is acidic, the more likely you are to get caries.

Also, just because Diet 3 is a lot better than Diet 1 (and 2 for that matter), that doesn't mean that Diet 3 is the ideal/best diet. We would need to research this more using Diet 3 as the starting point.
FYI, if you liked this talk you might also like 'Programming Collective Intelligence'. If you haven't read it already...

http://oreilly.com/catalog/9780596529321/
OK, I'll bite. Tell me what's wrong with what he did.

A person needs money to feed their children and will be broke 3 days before payday. That person can either (a) not get any money at all, or (b) borrow it at a high rate of interest. What, exactly is wrong with option (b)? Don't add extra details like hidden gotchas, loopholes, what happened to a friend of your sister's etc. What is wrong with the situation exactly as I proposed it and why do you find it unethical?

Likewise, if I decide to snap up a property in distress and rent it out, why is there a (as you put it) "serious problem here?" Why is it better to just let the property rot? Again, answer to the facts instead of letting your bias add conditions I haven't specified.

I'm serious: I'm approaching this with an open mind. Tell me why I'm wrong.
But they're both sides of the same coin for Amazon. They had to build up this infrastructure for their own use, and that's why they can do cloud hosting so efficiently. It's like when they had a9, which was a pretty cool search engine (I used it for a while); they've naturally got a really hard-core search engine in house that works on rich data just for their own mountain of data. It's the same for most of the other stuff that they've done.

I really think Amazon parallels Google in innovation, but they've somehow stayed much less sexy in the hacker world. I suppose it's that Amazon hasn't needed to make "we're smart people" one of their selling points.
Can you teach me how to program?
Great point. Actually you have to use your browser. It may be useful for someone who does not have an irb console to play with at the moment, or for someone testing multiple strings in one unique batch, which will be a future feature I'd like to add.
Why is the article wrong?
The article uses Microsoft as an example of iterating (from Windows 3.0 to Windows 95).
I see what you mean about the infrastructure, and its a good point.

But as to love for Amazon... I dunno, most hackers I know have disdain for Google at this point, and much love for Amazon. But then... I am cloud obsessed, and this influences who I associate with :)

Amazon enables us. Google... not so much.
37signals' follow up on "Get Satisfaction, Or Else..."
Very good article. I'd also like to mention that as a libertarian I strongly desire to see efficient free markets and those require INFORMATION.

Attempts to hide information are almost always market manipulation.

In the case of secret salaries, the market is being manipulated for the benefit of employers and employees who are very good at salary negotions in addition to their other skills.
I'm impressed with how Jason handled it. GS made some changes that sounded good enough to me, but after reading this post, I'm firmly on 37signals side. GetSatisfaction is a good idea but it's presented very deceptively and has the potential to hurt customers as much as it helps.
sorry didn't realise the email field was hidden from other users. cheers i'll send you a message :)
The whole current commotion is an attempt to avoid a horrific depression.

Those efforts will hopefully succeed, but I don't know anyone who doesn't think success == slow or slightly negative growth for a very long time, much like Japan.
You ate a paste that straightened your teeth?
Post this on stackoverflow
Google Lifts Its Skirts
Commands don't need to be obscenely cryptic and if they get too long you can easily teach autocompletion. If you have basic verbal skills, then you know stuff like context, so there should be no problem with the "variable feedback". I used DOS when I was 5 - learning to create text files, run programs, navigate the file system wasn't hard at all. My mom explained to me those things only once or twice. I certainly didn't need to "hack" anything in any sense of the word.
Not much. Facebook makes almost nothing off me, Twitter doesn't make money off anybody, reddit & hacker news both have very little or no ads.

CNN / NY Times / Local news. I RSS all of it, so no money there....

I have found myself buying from Mac ISVs a lot more recently. Macheist, Coda, a few games. All within the last few weeks. Not quite my "favorite sites", but I am giving somebody some cash.

And yeah, Amazon. Although it's not in my favorite sites list either, it's just a well run store.

So I suppose I only pay for goods, either physical or digital, and not content.
Looks like some code that has to be run through a couple JS functions before it's legible. I tried seeing where it actually happens on the site and can't find it. Regardless, it has already been "cracked".

http://www.hulu.com/channels/Action-and-Adventure?ajax=true&...

(That's a link from the article, I can't see anything like that when browsing through the site. It's all plain text for me.)
I did not eat the paste. I applied the paste to my teeth with my finger and let it set for approximately 30 minutes. I did this once a day for several months right before I went to bed.
I'd wait on your purchase... the current models will handle 360p okay via Hulu but will lag noticeably while trying to run fullscreen or even windowed 480p. I really think the next major selling point for netbooks will prove to be more HD video capabilities. VIA and Habey have already introduced hardware decoders (the VX855 and BIS-6550HD, respectively) that are able to handle 1080p. These or something similar could easily be included in next-gen netbooks.
I don't see where he says anything about straightening.
Fail. We don't need another subprime lender. This country has seen enough shenanigans from IndyMac, Countrywide, and the other clowns on Wall St. Entrepreneurs, find something else to create because this is a lousy way to make money and taxpayers are done with bailouts.

If you still want to do finance, see this link from HBS for ideas on how to build a nontoxic, sustainable form of it:

http://blogs.harvardbusiness.org/haque/2009/04/manifesto.htm...
strengthen: To make strong or increase the strength of.

It looks like straighten but it's a different word.
I couldn't get past the 1995 background, but I was hoping for something more then just the usual brief summary of here's how this might work.

Sadly this is not it, but perhaps people interested in this can contribute insightful, up to date and detailed comments on the state of related technology?

Does anyone know the latest on carbon nanotube based materials?
As a former pro-gamer (sponsored by Diamond Multimedia for Counter-Strike... remember them?) turned pro-hacker to pay the bills, the future for pro-gaming seems bright.

Quake-live is a great example of a game that could really become the next "basketball". It can run on almost any computer (10 years old) and the gameplay has stood the test of time which shows how incredibly balanced the game is.
Creating a platform that can be built on is the way to go - but it seems very difficult to create one that is simple to use, that can generalize in the right ways, and enable people to build what they want.

But maybe that's not the trick - it isn't that hard to make an overgeneral, loose platform, that isn't specialized towards any particular usage. Maybe the particular platform isn't that critical. Maybe the trick is just to provide access to something that is really cool and exciting (that simple core idea). Developers are clever, they'll work out how to get on the bus.

I'm not sure if this applies to Rails.
Read some of David Sirlin's stuff (like his book "Playing To Win" http://www.sirlin.net/ptw/) and see how lazy you think competitive gamers are.
So, wait the article says that freelancing benefits both employer and contractor?
What’s an example of Ruby code that’s "too clever"?
The risk/reward equation in health care research is completely out of whack.

Obviously researching drugs, medical devices, etc, can kill people. But my god, the greater benefits we could have if testing a new drug didn't cost BILLIONS.
On the Speed of Light, Innovation, and the Future of Parsing
"Companies such as that is vitally necessary."

True, but I was not saying they weren't.

"Also, it is a free speech issue"

No, it is not. Nobody here has said GS shouldn't exist or be able to collect complaints about companies. They've only criticized them for doing things that verged on impersonating those companies by making official-looking "customer support" pages for them.

The only anti-free speech remarks made have been those by a very few people accusing Fried of defamation.
Also on scribd: http://www.scribd.com/doc/10957390/John-Taylor-Gatto-Undergr...