skysight-inc/HackerNews huggingface dataset:
The way they did this is shady and annoying. Why don't they use some kind of opt-in. For example a button that says "Mention my sign-up on Twitter".
Apparently, Google's dominance is coming to an end and Facebook is the biggest challenger of this. For one after another Facebook is just occupying Google's ground in every aspect.
The javascript involved does seem overly complicated for such a simple task. Maybe it was originally intended for something else and somehow found its way onto this page?
It depends what you mean by "results". The genetic results are very accurate (a >99% call rate and >99.9% reproducibility rate).

However, medical knowledge isn't at a high enough level for these accurate genetic results to translate into truly meaningful medical results except for a handful of conditions. What does a 10% increased risk of getting diabetes mean to the average person? In practice, it means nothing, because you would act the same with or without this risk.

Second, 23andMe is already walking the fine line of not needing FDA approval. If insurance companies were to pay for it, there's a good chance it would require this. There are several conditions that can be self diagnosed through 23andMe that require genetic tests that cost more than $99 through your doctor, but each of those tests has gone through a medical approval process.
Click on the upper right (the 3 bars), which will show a left hand nav. From the left hand nav, scroll down to Settings.

From there, it is "Account Settings" and then "Notification Settings"
The Arch Grants competition is now open and closes on Jan 1.

What kind of startup do YOU have, readers?
He is right though. Many MBAs have to relocate, and they buy the cars just for the two years of their program.

(About the 2%, the sample is very different so that should explain the difference with the report)
App Ratings with Apptentive – #appdevchat December 13th at 10am PST
Interesting! In the past if you made an account on their site and signed up for the new letter (but never actually bought a test), after a while they would send discount offers. The last one I received was $50 off, but the tota l cost was still over $200. No I have no excuse (cost wise) not to try it.
12-12-12 12:12:12
It does not appear to me that the second gyro is intended to add reliability. Watch how the gyros move in the video: the rotors rotate in opposite directions and the frames twist in opposite directions to apply force to the vehicle chassis. That is necessary so that vehicle pitch motion is not coupled into vehicle roll motion by the gyro. So if one gyro were to fail, the vehicle would rock side-to-side every time it went over a speedbump.
Yes , but wouldn't Nbr 2 in itself be worth a lot if the patient would make lifestyle changes in response to increased risks highlighted in their genetic profile. Suppose you have a genetic proclivity for alcoholism, wouldn't most people watch their consumption a lot more if provided with that information.
The most plausible theory is that we will go extinct before reaching a "post-human" phase.
Completely pointless to perform these comparisons without adjusting for demographics. Finland is so homogenous they don't even keep demographic statistics about ethnicity. In the US, 12.6% of the population is black (and deals with the continuing effects of slavery and systematic discrimination/segregation that ended only 50 years ago), and 16.4% of Hispanic (many of them relatively recent immigrants, as well as being disproportionately in the lower socioeconomic calsses). I don't imagine Helsinki's public schools are filled with 90% minority students of whom 87% are low income, like Chicago's.

The problem in the US is not education. The problem is the education of poor urban and rural childern who are parts of ethnic minorities. In the US, we segregate all of these kids together in schools that spend most of their time suppressing the resulting gang activity. We don't need more teachers, except in the inner cities, or better curricula, or more or less standardized testing, what we need is to tackle inner city and rural poverty and mitigate the effects of segregation that linger from the 1950's.
In the US, President Bush signed the Genetic Information Nondiscrimination Act of 2008 which covers these topics. Some relevant parts are available here: http://thomas.loc.gov/cgi-bin/bdquery/z?d110:HR00493:

edit: Specifically, "`(A) IN GENERAL- For purposes of this section, a group health plan, and a health insurance issuer offering group health insurance coverage in connection with a group health plan, may not adjust premium or contribution amounts for the group covered under such plan on the basis of genetic information."
Exactly, I suspect many U.S. states (e.g. Massachusetts, Minnesota) perform quite well against their international counterparts, but most news stories never make that point clear (or even at all).
Besides the edge cases and exceptions what you are told from a very young age is accurate. You can look at the income data for people who have univ degrees vs. those who don't.
I didn't downvote you, but it is physically impossible for spinning gyros, with their massive angular momentum, to suddenly stop without a sudden massive impulse of countervailing torque. Barring catastrophic (i.e. the driver is already dead) damage to the vehicle, there is no mechanism that can apply such torque.
Teachers/administrators/schools do not have their funding tied to the improvement of their high-performing students.

This is a natural by-product of the Texas model of educational reform (NCLB/Race to the Top/etc.): teachers cannot be trusted to teach and assess their students where those students might be (with regards to content mastery) so we implement standardized tests which focus attention on the lowest performing students (often overwhelmingly teaching them test-taking skills irrelevant to real life) and thereby reducing the time allotted to core curriculum for everyone. It's a system that only improves academics on a superficial level (raising scores without raising academic mastery) and diverts billions of dollars out of already constrained school budgets to private testing/content material providers (NCLB requires tests and other measures without providing resources to implement them - hence resources must be stripped from other programs or services at the schools).
http://www.evorack.com/unmanaged-xen-vps.php I've used EvoRack for about a year, and I'm very happy with them.
Great overview!

A few sidenotes:

b) TestFlight (https://testflightapp.com/) makes ad-hoc distribution marginally better. Adding new users to the build still requires grabbing their UDID and mucking around with the provisioning portal, but installing/updating to the latest build is infinitely easier for your users.

c) As long as you're not blatantly flaunting Apple's rules and bringing in hundreds or thousands of users, you can most likely get away with using enterprise distribution for beta testers. I've gotten invites to a half-dozen iOS apps built by friends who release their friends-and-family beta using an enterprise profile to avoid manual provisioning hell.
Swiss Neutrality
Congrats to ZenPayroll!

Side note: Since when is $6.1M a seed round?
23andMe works by testing only a subset of all genetic SNPs ( http://en.wikipedia.org/wiki/Single-nucleotide_polymorphism ). It's not full DNA sequencing. The newer DNA microarrays contain a greater number of SNPs that they test for.
Right, but is the DEC assembler the one in use at MIT? My memory (mostly from reading Hackers) is that their toolchain was a homebrew thing.
specifically?
Landing pages that work that way are most likely intended for lead generation. Sometimes it's a good thing, sometimes not.
Filming the Millenium Falcon
Wow, what a fun, inspiring post. Love it!

BTW, do not make the mistake of dismissing OpenERP as a small player in a market dominated by giants like SAP. OpenERP is asymmetric competition for those giants! The company's goal is to shrink the market, by taking away more of revenue from competitors for every dollar the company earns.

As Josh Kopelman of First Round Capital says, "We love investing in technologies and business models that are able to shrink existing markets. If your company can take $5 of revenue from a competitor for every $1 you earn – let's talk!"[1]

Congratulations to Fabien Pinckaers and the rest of the OpenERP team!

--

[1] http://redeye.firstround.com/2006/04/shrink_a_market.html
While trail and gyroscopic forces both influence steering and stability, neither are required. It has been shown that a bike can still be self-balancing even without trail or gyroscopic forces, though positive trail and gyroscopic forces do make it easier to balance and more stable (see http://bicycle.tudelft.nl/stablebicycle/StableBicyclev34Revi...).

ithkuil's comment is the more accurate description of what is going on.
They aren't giving you the results of a complete sequence ($$$). They are looking for genetic variants. So newer tests will look for additional variants.

See: https://customercare.23andme.com/entries/21262606
Build Your Own Cloud! Just start typing. (BYOC gets you 25% off first invoice)
The law was already passed in the U.S.:

"`(A) IN GENERAL- For purposes of this section, a group health plan, and a health insurance issuer offering group health insurance coverage in connection with a group health plan, may not adjust premium or contribution amounts for the group covered under such plan on the basis of genetic information."
If you don't have an idea of what you want out of college it is best to figure it out fast. And even if you don't have an idea you are better off in college meeting a whole bunch of people and attempting to figure it out.
They are not mapping your full genome each time. They are looking at specific genes that are known to be linked to certain conditions or attributes. When they release a new test, they are sampling more genes and therefore can find more potential conditions or attributes about you.
Category 2 appears to be worthless for me. For many of the risks there, I have conflicting results (i.e., 5 studies were done on this disease and according to 2 of them, I'm at increased risk while the other 3 indicate that I'm at decreased risk).
Wordpress is its own PHP framework; in fact, PHP itself is a framework, provides everything frameworks do from database querying to templating.
Yes, and it's a bubble waiting to pop. It's alleviated somewhat by the high interest rates (8%) and non-dischargeability in bankruptcy, but yeah...
But if one is predisposed to alcoholism, they might think, "Why even try to fight it? I'm going to succumb at some point anyway, might as well give up now and just enjoy it."

This is just to say that that sword has two edges.

EDIT: Made it abundantly clear that this is not my own personal fatalistic perspective.
The very restrictive nature of a template pseudo language is one of its beneficial attributes. If, for example, you use PHP to create your templates then the very power and flexibility of PHP allows you to make a "quick fix" for a model issue in the template, or a function call from the template, and next thing you know your template is no longer just a view, but instead a messy hodgepodge of code along the lines of what you often see when you open up the typical WordPress template.

The template pseudo languages enforce a strict separation between model and view, and they typically do so with a much more concise syntax and legible format compared with embedding PHP in HTML, for example.

I used to prefer general languages for templating, but once I learned the pattern of using Twig to the full I found that I could create templates much faster than before, and I could also go back to a template after a couple months of not looking at it and quickly understand what I was looking at.
> I think the goal of the campaign is to plant the seed in the general public that record labels bankrolling capital for artists to produce albums is no longer needed with today's current technology.

It really isn't if you already have somewhat of a following. A band I listen to has funded their past two albums on kick starter and the tours associated with them. The idea they went with is, "Prepay for our music, once it is recorded we will release it for free and not prosecute pirates."

This allowed them to completely avoid worrying about piracy or anything like that. I've linked their previous Kickstarter below. I doubt many here will enjoy their music (Christian noise rock. [note, I'm not Christian.]) but people might be interested in seeing how they operated their Kickstarter and their business model.

http://www.kickstarter.com/projects/Showbread/showbread-canc...
Why don't we just make high schools better?
Ask HN: How Much Would You Pay To Be Resurrected? 
How Much Would You Pay To Be Resurrected?

Undoubtedly their will come a day when people can purchase resurrection insurance where in the event of one's death a clone of theirs will be raised and given whatever contractually agreed upon care/resources the provider is bound to. Or perhaps simply the eccentric ultra-rich will have an interest in such things as this and set everything up by hand before they die, entrusting the future of their clone(s) to personal butlers, lawyers, handlers, etc.

So how do we provide this service? Ought it be provided. Would you take it if it were free? Say for soldiers going to war, or people with genetic diseases, with a clause to wait until a cure is found? Boba Fett may be a fictional character, but the idea of raising one's own clone as one's son or daughter is appealing to me personally. As a transgender woman, I can't procreate. I waited to transition until I was 24 in order to avoid my mother's ire. How would a being with my genes raised in a different environment turn out, one where I was their mother and thus could insure that their best interest, rather than my personal beliefs, played the most important role in their nurturing? Of course, no human life should be brought into existence simply to satisfy a curiosity, but my whole reason for bringing this up is to start a discussion about the morals and ethics involved. My mirror neurons tell me just bringing it up will make people think I'm a sociopath. What does that say about us? We exclude people from the tribe when they bring up things that make us question our humanity in ways we don't already have set answers to; that which we shall not speak of, and only monster's can fathom.
Hue: A toaster that perfectly toasts your bread by color
It's awkward to embed Python in a pipeline and the awk can be quicker to write if the problem suits its domain. Execution speed may be slower than Python, depends on the work needed and the awk used; gawk, mawk, Kernighan's One True awk, ...

awk 'NR > 3 && !/foo/ {s += $(NF - 2)} END {print NR, s + 0}'
That's not factoring in the opportunity cost. Which to me would out weight the 185K sticker price.
Wow, I had not even thought of that. If the integrity of the frame is compromised during the collision that seems a very scary prospect.
"labor arbitrage"? You're saying it isn't fair because the middle income country selling phones to the low income country isn't paying money for high income workers instead? I can sort of understand why someone could think that it's good that phones sold in a country are made in that same country, but insisting that all phones sold everywhere be manufactured in the first world just exhibits a breathtaking sense of entitlement.
> And what if UHC raises premiums on everyone that does not take this test?

Don't think that's legal.

> What if employers require their employees to do this much like drug / background checks?

Also don't think that's legal.
Can't agree enough with Slicy. It has saved me hours of time and headaches, as well as my designer. I think it's the kind of tool that has to fit your workflow, but if it does, absolutely worth it.
So cool, I remember playing it on my old Amiga \o/
Norton Survey: 27% of Women Would Rather Skip a Shower Than Fix an Old PC
Contiki Regression Tests: 9 Platforms, 4 Processors, 1021 Nodes
I'm still just not sure I really want to know all these things... it's just low-hanging fruit for any hypochondriac tendencies :/

But, fantastic nonetheless.
I am a one-man-band with an S corp. I would love, love love it if something like ZenPayroll would help me with the 941's, state taxes, and eftps but its too hard to justify offloading that stuff at $30/mo ... $360/yr... when Bank Of America offers their kludgy software for free with my business checking account and when that fails, just manually process them.

It has been a constant inconvenience of mine since I incorporated myself 6 years ago.
Also, California has put a more stringent law on the books in 2011: http://www.privacylives.com/california-passes-bill-to-prohib...
It's not just privacy or human rights; it's an apparently pervasive misconception about what insurance is.

The premise of insurance is that you are insuring against the unknown. If you know that something is the matter with you, then it's no longer insurance. It's getting someone to pay for a treatment that you know you will need. Whether other people should be paying for that is another discussion.
It seems like the data in the "Teaching math to the Talented," article refutes that assumption.

"In short, the incapacity of American schools to bring students up to the highest level of accomplishment in mathematics is much more deepseated than anything induced by recent federal legislation."
Broadly speaking, because there are laws on the books that prohibit using genetic information for health insurance discrimination.
> (not java bashing - don't see why this couldn't be solved in java)

Chromium is c++. The code diffs in the bug report are c++. Where is Java coming into picture?
Let's go with your example. Let's say you have a 50% increased risk of alcoholism than the average population.

What does that mean?

If the probability of alcoholism is the general population is 1% ... well, that means yours is 1.5% ... or still ridiculously small.

Obviously those are just numbers I'm using to illustrate a point, but you see where I'm going with this.
Magnus Carlsen to beat Kasparov's all time high rating
I'm with you! I just posted this on the other ZP thread:

"I setup payroll awhile ago and it took me a long time to find a provider. I remember looking at Intuit, ADP (for a second), and SurePayroll; I think I'm also on the ZenPayroll invite list.

After going through some of the threads on HN I decided to use BOA -- which is essentially Intuit -- and although it was a pain to setup, it does seem to be working. (Total cost: $30/month)

However, the Wave Accounting team reached out to me recently to let me know that they'll begin a full service payroll SAAS in January with pricing at $5/person. You can bet I'll be trying it out.

Sadly we're too small for ZenPayroll's pricing to make sense at this time."
> non-plumbers don’t care about the aesthetics of plumbing

Of course they do. Nobody wants crooked pipes in their house, or pipes visible where they need not be.
Pointer Media Query
It isn't entirely fixed, but what's changing are 23andme's tests: both genotyping and sequencing prices keep falling, so periodically they can upgrade the chips they use to ones which either cover more SNPs or improve the error rate (>99.9% accuracy still means a lot of errors on scores of thousands of SNPs) or both.
Can you explain this a bit more? It sounds interesting.
There was a talk about OpenERP at Montreal-Python about a month ago. The video of it is not up yet but will be some time soon here: http://www.youtube.com/user/MontrealPython

Also, there is a Montreal (EST time zone!) based consultancy company called Savoir-Faire Linux that are involved in the development of OpenERP, and can help you with any implementations.
It wouldn't really be WordPress anymore at that point. You're likely talking about a rewrite of virtually every bit of code.
http://goatkcd.com/619/
Personally, I would consider the minimum between contact times to be a full business day, but in reality I'd usually wait 3-5 days. That said, I have never been in your position where I was short on time and options, so I would probably have done something similar if I were you.
They ran an exome sequencing pilot recently, so sequencing is certainly coming.
The real world? You are in the real world. There are always ways to make things better around you, no matter what situation you are in. If this is hard to think of, then start by writing 5 things that could be better/easier every day. Then increase that by 5 every day until 50. Then you will see there are opportunities everywhere. Also, I mentioned that you should read Paul Graham's essays and The Lean Startup.
I don't understand why the crash happened when visiting Gmail if the bug was in Chrome Sync.
I think this isnt a good solution. Imagine the following scenario.
A disease hits with p=0.001. To cure it is Very Expensive. Everyone gets insurance that covers it.

Now imagine we have a test, that can predict it with certainty. Very soon only those with positive results will want insurance. The insurance against it will become unprofitable and discontinued.
Great question -- I often wonder if the repeated "failure" in the core classes was also discouraging in being more ambitious. Obviously I'm not going to advocate for less math/science/english for someone like him, especially through at least high school, but I can't imagine it did wonders for his confidence repeatedly being required to attend after school tutoring, having to get his parents to sign failed tests, etc.
How-to: "Zoom to 200%" shortcut on Retina Photoshop CS6
Gender is determined genetically, and men and woman have different life expectancies. Does this mean you can't charge men and women different rates (all else being equal)?
No, it's not. It's a false rationalization of your (lack of?) ability as a CEO to motiviate the best performance out of your staff to write off all your staff as 'B' and 'C' players.
First step would be to join two plus two forums and start asking questions. There are so many books about poker but two stand out in my mind right now - Skalnsky's Theory of Poker and Ed Miller's series on Limit and No-Limit poker. There are many variations of poker and some of the latest flavors are pretty interesting, but No-Limit Hold'em is the most popular.

Poker can be very lucrative but it is a tough game mentally. I played full time for a year and packed it up. Too much stress, as crazy as that sounds coming from a software programmer. I tracked it all and my database proves I'm a winner but at that time the game was dwindling and it just seemed like a tough future. Online in the US now is pretty brutal. Live is still a cake walk if you know your game.
Knowing a little bit about the culture of the company, I hope that they will be transparent about any laws they have to comply with, a la Google Transparency report: http://www.google.com/transparencyreport/removals/government...

To my knowledge, this has not come up yet, but I'm sure it will one day.
Private Spaceship Builders Split $30 Million in NASA Funds