skysight-inc/HackerNews huggingface dataset:
Of course you're right; I'm using colloquial shorthand. I'm referring to apolipoproteins bound to lipids and cholesterol (at which point we can call them lipoproteins). What I really am talking about is VLDL-cholesterol, LDL-cholesterol, HDL-cholesterol, and triglycerides.

awolf's challenge is particularly relevant and on-point because extremely low levels of LDL-cholesterol from birth (hypobetalipoproteinemia or abetalipoproteinemia) is associated with neurological deficits. When caused by defective APOB, it is also associated with non-alcoholic fatty liver disease.
You could always just put it in the first go, then if you get any traffic, replace it with a more efficient option. Most people never get enough traffic for percent cuts to matter anyway.
More people want Romney to be TIME's Person of the Year than Marissa Mayer
Microsoft: Don't Get 'Scroogled' By Google Search Results
New York City celebrates day without violent crime
google alerts
meh, just in my lifetime, I've seen the outsourcing of memorization. Would you be able to do your job without a search engine? I wouldn't.

Facial recognition (if you limit it to a limited number of faces) is already pretty good.

I mean, yeah, my cognitive abilities degrading is also about the scariest thing I can think of, too, but eh, we are developing new crutches at a reasonable rate.
What is the function of LDL (bad?) cholesterol in the body?
Good thing he's chairing the next House Science Committee.

http://science.house.gov/press-release/chairman-hall-congrat...
I'm totally using Artsy Head in my christmas card replacement strategy...
4 Funding Campaigns in 1 with MoustCache Social Network
I was there!! At least we got free shipping on our Guinness World Record certificates. I think they were charging $30 or something for it, which was ridiculous.
Preventing disease by preventing age could be an unending justification for prolonging life.

Yes, I hope so. How on earth is that a bad thing?
What they're lacking is not professional management, but the rule of law.
Like when you could reply to Facebook posts via email? http://i.imgur.com/lGQ1Y.jpg :)
I stopped reading at this point:

Commercial hacker hunters -- who refer to the team as the Comment group, for the hidden program code they use known as “comments” .....

/facepalm
the single best sentence in the whole text

"Seeing what everybody does, thinking what nobody does."

i would change it a little.

Seeing what everybody does, thinking what few do, executing like noone else
I think you're misreading what I'm saying, let me see if I can be more clear.

The key goal of an orbital launch vehicle is generating the necessary speed for orbit (over 8,000 m/s, around mach 25). The difficulty of reaching the altitude of low Earth orbit is inconsequential in comparison. A rocket has the advantage that it can do its accelerating wherever it's more convenient, so the typical flight profile is first up and then over, because it's a hell of a lot easier to accelerate and travel at high speeds above most of the atmosphere. For example, the Falcon 9 reaches an altitude of 5km before it even goes supersonic, and will reach an altitude of 30km within the first 2 minutes of launch.

An airbreathing engine however needs to stick around in dense enough atmosphere for its engines to work. And if a vehicle relies on a significant amount of airbreathing then it needs to spend a significant amount of time in that denser atmosphere. And that means that it needs to do more of its accelerating in denser air, which means that it will encounter higher aerodynamic forces, higher drag, more heat issues, a higher max-Q, etc. Those sorts of forces tend to be the "long poles" that aerospace vehicles are designed around, it dictates everything from the materials used to the type of construction to the service life of the vehicle's frame, etc. This is something that positively cannot be avoided for an airbreathing vehicle.

Sure, the SRBs generate a ton of thrust on the Shuttle, but they also help push the Shuttle quickly to higher altitudes and lower air pressure. Before the Shuttle hits mach 2.5 (of 25) it is already at an altitude where atmospheric pressure is 1% of sea level.

As I said before, mass isn't the big driver of cost in orbital launch vehicles, cost comes from complexity which comes from operational complexity (flight profile, staging, etc.) and design complexity (engines, control systems, handling, etc.) A vehicle which saves fuel but increases operational complexity is not a cheap vehicle. Fuel costs around $1,000 a tonne, whereas an engine can easily cost $10,000 / kg.

The biggest win that a vehicle like Skylon would have initially is that it might make it easier to make reusable launchers. If that's the case then even an expensive launcher which can be reused only a handful of times might still be useful in reducing overall launch costs. But if an entirely rocket based vehicle can be made to be reusable then it's very unlikely to have better overall economics or operating characteristics, for all of the reasons I've listed previously.
Wow, 70k for a glitzy closed source web site? I'm much more impressed with things like npm-www which are clean, effective, and great examples of using the language in their own right.
Wisconsin produces half as much food as California[1] with 50 times fewer illegal immigrants[2]. I won't vouch for that site's data but having lived in both states I don't see any reason to distrust these particular numbers.

[1]http://www.statemaster.com/graph/ind_foo_man_tot_val_of_shi-...
[2]http://www.statemaster.com/graph/peo_est_num_of_ill_imm-peop...
Documentary photographer uses iPhone
I think what is more important is that since this administration took over, rejection rates for skilled visa applications have skyrocketed.

http://www.indianexpress.com/news/obama-warned-over-h1b-visa...

As someone who has had to respond to two RFEs so far - once for my initial H1B application and once for my green card application, I get the feeling that I am not wanted in this country. I have seriously contemplated moving back overseas more than once.
It really makes sense from a negotiation standpoint. It's generally expected that immigration reform will be a banner issue for Obama this term, and this bill was likely an attempt by the Republicans to get out ahead of the issue before more sweeping legislation is introduced.

By refusing to cooperate on this bill, it signals that the White House and the Senate are unwilling to let the Republicans pick and choose on reform, meaning that the issue is going to be addressed in the more comprehensive manner that the Democrats feel is necessary.
They spoke French, having adopted it after their conquest of, and settlement in Normandy. French, not Norse, was their court language both in Normandy, and later, after the 1066 conquest, in England.
Aside from speaking French and having previously lived in France. (We all are Africans using your logic.)
There's another dimension to be looked at here - especially in India's case. I'm currently enrolled in a Bschool and my class mostly comprises of students from an engineering background. Most of them have joined an MBA program to switch careers. Their primary argument is that they were forced to do engineering and when they figured out that they'd rather be doing something else it was too late. Since none of them wanted to spend their early life debugging code for big IT company (read: TCS, infosys) they preferred to do an MBA program.
I think that MBA's teach a very valuable thing (also found in undergraduate commerce degrees): How to efficiently and effectively work with different types of people in teams.

No one ever addresses this issue when talking about the bad aspects of MBAs.
Heh, I worked a floor away from Dr. Szostak the year he won the Nobel. (Purely a curio, I've never met him and his knowledge didn't osmose my way.)

Call me boring, but my opinion is that telomerase activity is good until it isn't, just like everything else. However, Yamanaka's iPS work is a good reminder that sometimes manipulating a surprisingly few substances (4 proteins, in his case, leading to induced pluripotence of previously differentiated cells) is all that is needed for profound effect.
I agree, I think another way to put it (to quote someone else), an idea is worth $20. I think execution of an idea (with pivots off early customer insights), brings it!
Good points. vc requires some governance and BOD level skills. [1] angels may or may not have, they tend be more product focused and hands-off. etc. Look at the problems YC was having winding down with "founder breakups" etc.

_________

[1] in addition to cash, business skills, contacts, etc which are obvious but omitted for brevity. angels if they have these skills is more likely from previous works, and not from being an angel per se.
Gotta agree with you on the nonsense in that statement. Economic advancement maps very closely to increased availability of energy resources better than any other correlated factor. I'd suggest that's more of a driver than professional management qualifications. Psh...
What do grad students in math do all day?

http://www.google.ca/search?hl=en&q=%20exp%28-%28%28x-4%...
GLSL isn't exactly beautiful all the time...
Absolutely. Rule of law trumps every other factor when it comes to long term success. You can mask a lack of it by flooding a local market with subsidized resources for a while, but that's not sustainable.
A simple and generally correct statement: LDL particles deliver cholesterol from the liver to the cells throughout your body. Cholesterol is water insoluble, so it needs a carrier; the apolipoproteins (ApoB, which is the key protein component of VLDL and LDL) are those carriers.
Regardless of people lying about using Stripe or what ever processor they claim, you still don't have any guarantee that their backend system is secure and treating your credit card information properly.
Have you ever witnessed senile decay of that sort?

I mean, said family member won't be helped by something / anything like Google or a notes app on a smartphone.

She fails the three-word senility test, wherein you ask her to remember three simple words, distract her momentarily, and they're gone. Every. Single. Time. In addition, she thinks her dead husband is overseas checking out a property, doesn't recognise her grand-children, has no idea what year it is, and can't hold down a conversation.

Outsourcing of memorisation is only helpful if you've sufficient marbles left to use the tools. This sort of problem needs a hardware fix - medical, cybernetic, you name it.
This is a complete WAG, but if I were to take a stab in the dark, I suspect the makeup of Wisconsin's agriculture industry is rather different than California's.

It looks like Wisconsin's industry is geared largely toward livestock and dairy, with fruit and vegetable crops largely composed of things like cranberries, corn, and potatoes:

http://www.aae.wisc.edu/pubs/status/docs/status2012.pdf

California, on the other hand, apparently produces "nearly half of US-grown fruits, nuts and vegetables."

http://www.cdfa.ca.gov/statistics/

It's my understanding that migrant workers in CA are largely employed picking fruits, vegetables, etc.

Again, I'm by no means speaking authoritatively here, but there's certainly more to this than simply comparing the dollar-value of each state's combined agricultural output.
the problem with this argument is that there is not an unlimited capacity for telcos to transmit these messages. if 1,000,000 people decided they needed to send a message to mars in the next 6 hours, you can bet your ass those messages would be $25.00 each, or more.

it's also not fair to simply compare the amount of data. when you send a message you're borrowing a channel / band. the transmission tech and spectrum has a certain capacity, that's why it gets auctioned and licensed for big bucks. i would also not be surprised if telcos spent 400 million maintaining, updating and building out the infrastructure. btw, someone correct me if i'm wrong here.

i'm not defending the fact that text messages are extortion in every sense of the word and the reality that they're more expensive than a real-time voice call is the part that's really hard to grasp.
The way Schrodinger said it

"Thus, the task is, not so much to see what no one has yet seen; but to think what nobody has yet thought, about that which everybody sees."
Actually a lot of poor countries don't qualify because there are already too many of their citizens living in the US, legally or illegally.

That's the "diversity" part, and the list includes many rich countries too.
Saaspose REST API Features Implemented in SDKs During the Month of November 2012
As someone who shares many libertarian views, I don't really feel that they are part of his target audience. He bashed Ron Paul when he was campaigning and he posts articles that often seem to ridicule constitutionalism and libertarian-ism alike.

I started reading the Drudge Report a couple of years ago, but the more I read, the more I feel like he is catering to racists, homophobes, and the other extremists that have destroyed the republican party.

Disclaimer: I share many libertarian views, but I also believe in many things that would be considered "liberal." Dividing politics into clearly defined parties only inhibits honest self-assessment and productive conversation.
The HN reaction to this story is pretty sad, I have to say.

Yes, journalists are poor at providing technical coverage. That's not really their job.

Yes, this guy could have created a more secure network system, but if a government hacking group comes after you, you will likely not do any better.
Ask HN: How might Space X test hull integrity on recycled rockets?
Hmm.. $220 for 30 pills:
http://ta-sciences.com/cgi-bin/xflow/shop.cgi?catid=0&us...
I find this mentality, one I've often found in the US, disturbing.

I've had the benefit of living the better part of a decade in Europe where data privacy protections are stronger, and there is a resulting expectation that companies can only do with customer-provided data what they had agreed to when it was supplied. That means only using data for the explicit purpose it was gathered and not changing or using the data for expanded purposes later.

It is bizarre to me to think that one should just accept that the receiver of the data can unilaterally expand the use of it later without informed mutual agreement.
My text messages in Australia are still $0.25, although thats probably because of the "cap value" plans we have.

Lets not get started on mobile "data" charges.
> It should be obvious that if you add engineers, prices will go down.

STEM is not a zero sum game. Adding personnel does not simply cut the pie into more pieces, it grows the pie. It's OK to get fewer dollars if those dollars can buy a self-driving car or a cure for Alzheimer's disease.
Why Andrew Mason Isn’t The Problem At Groupon
I think one of the problems is that you only gain the benefits of using their app if you use their debit card. Credit card points are just too good to pass up.
I think US has incredibly cheap electricity.
Don't they need to go through PCI-DSS certification? http://en.wikipedia.org/wiki/Payment_Card_Industry_Data_Secu...

I think those who've received the certification are pretty much worth the trust. I don't see anything like that on stripe.com homepage though. Ditto for paymill.com.
The Future as Foretold in the Past
Being in Australia I should mention that I don't pay for text on my $30 a month plan :)
Oh, you mean like this?

http://www.plasma2002.com/epb/
Twitter’s Response To PeopleBrowsr Lawsuit: ‘This Is Contracts 101′
induced pluripotence > http://en.wikipedia.org/wiki/Induced_pluripotent_stem_cells
A lot of the comments about this presume that the victim could have avoided such trouble with better security knowledge. It's worth noting that the Chinese have hacked Google, Yahoo, Adobe, Lockheed Martin, and over a hundred other companies, which have many more security resources available to them than Solid Oak does. No small business in America would ever be able to defend itself from a sustained attack backed by the resources of one of the most economically powerful nations on earth. For example, does anyone here think they could defend against years of attacks from the NSA?
https://stripe.com/us/terms

7. Security:

Stripe maintains commercially reasonable administrative, technical and physical procedures to protect all the personal information regarding you and your customers that is stored in our servers from unauthorized access and accidental loss or modification. However, we cannot guarantee that unauthorized third parties will never be able to defeat those measures or use such personal information for improper purposes. You acknowledge that you provide this personal information regarding you and your customers at your own risk. We recommend you review our Privacy Policy, which will help you understand how we collect, use and safeguard the information you provide to us.
Let's not forget that Old English also puts prepositions at the ends of sentences! That's not a valid argument for a claim of closer affinity toward Scandinavian than Old English.
These plans make it impossible to compare between the companies -- I hate them! $30 gets you $200 credit with one but $300 with another, the first might have $0.25 texts, the second $0.20, the first might have a flagfall, the second might not. I wish the ACCC would make such things illegal.
Why? It's seriously what they do. The user installs the malware, it goes to a normal looking web page checks the html comments and receives it's commands. On the face of it everything looks fine to the user but the malware knows then what to do.
Yeah, but you're still sensationally wrong. PGe may have been spoken in Scandinavia, but that's not even close to what people mean when they say “Scandinavian languages”. That means “North Germanic”, or, languages which are descended from Old Norse. As opposed to every other Germanic language, like German, Frisian, Dutch, Old Saxon, Old English, Gothic, etc.
Bit-'Wise' Magic
https://stripe.com/us/terms

8. Data Security:

You are fully responsible for the security of data on your website or otherwise in your possession. You agree to comply with all applicable state and federal laws and rules in connection with your collection, security and dissemination of any personal, financial, Card, or transaction information (defined as “Data”) on your website. You agree that at all times you shall be compliant with the Payment Card Industry Data Security Standards (PCI-DSS) and the Payment Application Data Security Standards (PA-DSS), as applicable. You agree to promptly provide us with documentation evidencing your compliance with PCI DSS and/or PA DSS if requested by us. You also agree that you will use only PCI compliant service providers in connection with the storage, or transmission of Card Data defined as a cardholder’s account number, expiration date, and CVV2. You must not store CVV2 data at any time. Information on the PCI DSS can be found on the PCI Council’s website. It is your responsibility to comply with these standards.

What this means is once you make a payment, you are at the mercy of the vendor you're making payment to. If the vendor does anything mischievous (which shouldn't be difficult at all), you're on your own. :)
Put an equal torque on the back of your head, then distance doesn't matter so much (aside from overcoming inertia when moving your head).
If immigrants benefit from social insurance, the whole equation falls apart. But you can't allow immigration and then refuse social services, so.....
This is a great idea. I guess it would be more like contracting though. The ideal case would be oversubscription: Stuff that needs to be built really benefit of having several prototypes built, and the best approach selected for further development.
LeBron James's son Lebron James Jr. picture
OP is a girl :)
Show HN: Find relevant domain suggestions quickly
Just don't start fiddling around in your crawl-space looking for bugs! </pun-intended>
The US economy is doing poorly because of energy policy, not population size.

> Billions of dollars could be raised by turning these into entrepreneur visas or charging per visa ...

Billions of dollars would be like pissing on a supernova. Putting out the fiscal fire will take trillions of dollars in economic reform and growth, and immigrants have historically been a big part of American boom times.
What organization within the government is so vain that they can't use a great piece of technology due to a mascot?
After much deliberation, I deleted my Facebook account around 1.5 years ago. I even ensure that nothing from Facebook can be accessed from my computer.

Like you, I have lost out on the weak ties, but have decided that I would rather lose those than let Facebook know everything in my personal life and my activities on the web.
Sorry, looking back, my response wasn't very clear.

I didn't mean Stripe's backend, but the website owner's. Before passing the data to Stripe's API, the website owner might intentionally or unintentionally do something insecure with your details.

Meaning if you wanted to feel 100% safe with your transaction you may prefer to enter your details on Stripe's website where you trust that company and their implementation of security measures.

Unfortunately, if someone wants to try and trick a user into getting their details, there is an infinite number of ways to make their payment page look secure. Worse still, non-tech people wouldn't know to trust a company like Stripe as opposed to any other made up company.
Erlang Tic Tac Toe
Curious to see what percentage of the entrepreneurs in this study are starting 'small businesses' versus 'startups'.

Didn't Steve Blank peg it at 99.7%?
yes, this is a great point. raises the issue about experience: 10 years experience? or 1 yr experience repeated 10 times. Not the same thing at all. Do you really want to extend the latter ad-infinitim as 1 yr becomes->1 day->1hour repeated N times etc
from the Analysis that the article claims identified "thousands of lines copied of code" (sounds like they copied a blacklist):

We found evidence that a number of these blacklists have been taken from the American-made filtering program CyberSitter. In particular, we found an encrypted configuration file, wfileu.dat, that references these blacklists with download URLs at CyberSitter's site. We also found a setup file, xstring.s2g, that appears to date these blacklists to 2006. Finally, csnews.dat is an encrypted 2004 news bulletin by CyberSitter. We conjecture that this file was accidentally included because it has the same file extension as the filters.
Crowdfunding Options for Sex Projects
well yes, in his context seeing is the idea and, thinking is the execution, which might amount to written proof or the likes.
Mojito - A JavaScript MVC framework for mobile applications from Yahoo
A cpu less at load is a far more responsive cpu.

Atom was designed to be crippled from the start to save power.

You must be running smaller, single site servers, possibly with mostly static content?

I am willing to bet atom would choke on non-indexed searches, compression/decompression and encryption.

The Intel (and now AMD) aes in hardware acceleration for ssl is worth it alone on a real cpu vs atom.
ICloud and the problem with opaque sync
Financial Malware Detects Remote Desktop Environments to Evade Researchers
Dell, Intel in Talks for Stake in Sharp
Your question is not fair. I am sure there are cases where NSA tried an attack and failed. It is a matter of how badly they want the attack to succeed. Just because you are being attacked by "the Chinese" does not mean they will put all their resources behind it.
Python.org is getting a makeover