skysight-inc/HackerNews huggingface dataset:
As long as they're not fucking up the NIH grantmaking process, I (ruthlessly) don't care, and am not going to allocate attention to it. But once they do start fucking up grants, they're throwing a monkeywrench in basically all American therapeutic research and basic science, which is a big problem, since one of the government's primary missions should be to set in motion whatever things will end human cancer.
You're missing one critical aspect of this nightmare. After an incident:

"The AECL responded in two pages detailing the reasons why radiation overdose was impossible on the Therac-25, stating both machine failure and operator error were not possible."
It's odd because libertarian candidates usually only garner 1% to 3% of the votes. It does appear that there are a lot of libertarians that vote Republican because of the stigma third parties have, though. As someone who often votes for libertarian candidates, I can't understand it. Republicans are about as libertarian as a cheese sandwich.
I 100% agree with what you said, but no one looks back and remembers the people who voted against Hitler, or says 'there were some good people in Nazi Germany'.
When the federal government was created, the US had about 4m inhabitants and only 13 states, across a significantly smaller area. It didn't have electricity, telephones, the Internet, or modern plumbing. Healthcare didn't exist, labor safety laws didn't exist, food safety didn't exist, the FDA didn't exist. Women couldn't vote.

Complex systems evolve to adapt, gaining new subsystems to handle the new requirements. There have been a lot of new requirements since 1789.
Looking at history authoritarian power transfers usually start with a vote, or at least wide spread public support.
I think arcticbull is saying NIH is not necessary, essentially in favor of the freezes.
I just went through this with my car. All the OEM overhead interior lights were horrible 6000k+ type bulbs that not only made the interior feel like a hospital room but completely ruined my night vision turning me into the classic “Jesus!! You’re going to kill someone!” dad whenever my kids would fiddle with them at night.

I cannot overstate how much of a difference it made switching them all to 3000k warm whites. Of course instead of being replaceable bulbs they were all SMDs directly soldered onto little PCBs making it a bit of a project … but so worth it!
There's no such thing as zeitgeist. It's a fairy tale. And you're reading too much into election victories, which are almost always by very narrow margins. For example, the vote totals of Trump and Harris were separated by only 1.5%.

I'm not sure what you thought you were seeing 20 years ago. In 2004, George W. Bush was reelected on a very nationalistic campaign, and the US had literally invaded two sovereign countries, Afghanistan and Iraq, during his first term.

What happened to the rule of law and accountability? Do you remember the "War on Terror"? Do you remember the Iran-Contra scandal? Do you remember the Pentagon Papers? Perhaps you ought to lean into history.
Here speaks someone with no scientific training or knowledge of the NIH, public health, or how any of it operates.
You’re probably better off using a high quality converter to DC and DC lights
You are telling me Trump lied? Shocked...
The replication crisis stuff is mostly a message board fixation. The problem we have is that people unfamiliar with the field don't have a sense of what the denominator is, only the numerator. There is a truly gargantuan amount of NIH-funded research happening; NIH funds over 30,000 PIs per year, and those grants cover years worth of research, most of which involve teams of 5-10 people.

I'm not saying research fraud doesn't matter or isn't worth the stories written about it. I'm saying that people commenting on it generally don't have any sense of its scale, and fill in some very weird blanks about it.
iPad Pro M4 with magic keyboard, main/only work laptop. Have felt satisfied with iPads for a few years despite some annoyances in the evolving UI.

Topo Design 30L travel backpack. I travel constantly and live out of this pack.

Timbuk2 small messenger bag. Good for carrying iPad and other necessities for working remote, and as a "personal item" if an airline forces me to check my backpack.

Icebreaker merino wool clothes.

I pay for some software. Blink Shell (ssh/mosh client for iPad), Working Copy (git client for iPad), Control-D custom DNS/VPN replacement. I also use TurboTax, and resent paying for it every year, but it does handle everything I need as a freelancer living outside the USA.
The US is wholly inefficient with the Death Penalty, so I'm against it from a purely financial point of view. By the time many cases get to a point of being convicted they will have already served years, maybe even a few decades in prison already.

And yes, there is the open secret that the US uses its prison system as a form of soft slave labor. Many people don't want to reduce that supply.
I agree with you completely, but this gets at a debate that's been going on since the ancient days about whether democracy is actually good or not. Whether a tyrant is elected by a fair majority or inherits the throne at best (or Divine Right of Kings, whatever) makes little difference IMHO.

That said, while I have criticisms for democracy and do enjoy pointing out it's imperfections when people talk about democracy as some self-evident ideal, I do think it's probably the best system of government in a sea of less than ideal choices.
This constant false equivalence between parties is part of the reason we got here.

The Democrats are terrible but somehow I doubt Kamala Harris would be doing this much damage two days in. I don't think people would be wondering whether Tim Walz actually did a Nazi salute at the inauguration. It can be the case that both parties are evil, and they are, but that America still chose the greater evil.
Anyone else still find it weirdly amusing they are using the term aliens. Nowhere else in the world is that term used I don’t think
You come off as snarky, but I kind of agree. We tried this first.

It turns out digital collaborative calendars are pretty great for us in general, there is no chance in hell I could keep the analog one up to date, so it was definitely worth having a screen on the wall.
Back in the late 2000s I had my second encounter with the FBI (my first was talked about in another comment I wrote earlier today) I was hanging out with the world's leading web spammers and in those circles the 'replace words with synonyms' method was known but considered too low quality for web spam. Works for scientific literature though, where standards are lower.
There are, of course, not 20+ levels of management. The average fan-out in the federal government is 1:7 to 1:10, with ~2.5 million employees total.

That strongly implies 7-8 levels of hierarchy, on average.
Fibre in NZ -
1Gbps $55USD
2Gbps $74USD
4Gbps $82USD
Publication metrics. This has been a problem for at least the last few decades, especially when it comes to papers from some parts of the world. Before the current breed of low quality journals, we saw this happening with conferences that were often branded with professional societies like IEEE, but if you looked carefully it would be “IEEE Section of (random place in Asia)” and not a conference sanctioned by IEEE itself. Those used to be full of garbage plagiarized papers and junk. I think the idea is that nobody usually reads the papers when they make a decision based on publication metrics, so pumping a CV with garbage often goes unnoticed. It’s not a wise practice: in many places getting caught doing this would be a career ender.
174 scientists either at the NIH or funded by the NIH have won the Nobel prize.
https://www.nih.gov/about-nih/what-we-do/nih-almanac/nobel-l...

Odds are if you or someone you know has been treated with ... Any kind of modern medicine ... You have personally been impacted by NIH. That ignores the epidemiological knock on effects that we all benefit from oh and the whole "understanding of biological systems".

But screw it, they need to get in line with the party.
I am not in favor of shuttering one of the agencies responsible for public health, although I can see why my comment could be read either way. If you believe in reform there are compassionate ways to do it.
Thanks. And I assume that the web app allows them to do parameterization of ids etc?
Retro AIM Server – Open-source instant messaging server for AIM and ICQ clients
FWIW, a followup article indicates the island was auctioned off for $3.8M to the John Muir Land Trust and the former owner who attended the auction was then arrested on outstanding warrants.

https://www.sfgate.com/local/article/san-francisco-island-ow...
If you believed his disavowl, I've got a bridge... fuck it. Just give me your bank account number and I promise there will be $47 million in it tomorrow morning.
Ok, I understand the consideration and even a certain level of admiration for the capability of such a large population to govern themselves so effectively and shrewdly over time as to implement a new 5 year economic plan, every 5 years, successfully - that's an accomplishment...

There are quite actually empty skyscraper cities - with likewise massive corresponding infrastructural investments - this failure of central planning as an issue isn't always city sized but is widespread. It's a human thing... so it makes mistakes.

Like China's Navy specifically designed to insure dominion over the South China Sea... what's the point of that? To insure dominion? Now everyone is convinced China is going to be making moves for the top spot - bc that's what they signalled with such a Navel buildup.

They are rejecting the US Global Order and suggesting that China may be an increasingly better alternative for international Leadership... but they only have a mere couple decades left of economic growth before their entire economy will experience a population (and thearby economic growth) contraction like no peaceful society in history has before.

Who wants to sign up behind that wannabe Great Power?

Had China contented themselves with #2, we could have propped up an "adversarial" relationship political to seemingly dampen US Hegemony but in reality be each other's largest trading partners and whatnot - you know, like it used to be ;)

Now everyone knows tho - China's got a timer on it.
My understanding is that study sections have been cancelled and that is a key part of the grant review process.
Except it's not a coup and it's not a developing country but ok.

Drink some water.
Hang in there, this is a long overdue correction. It's gonna over correct a bit, but then things should be better than before. The rhetoric of Trump being a dictator is way overblown. If this didn't happen we'd be heading toward bankruptcy around the time your kids grow up.
I'd put that number closer to 67%: adding in the 90M eligible voters who, you know, didn't.
I suggest putting the link to the website in the about section on github. Currently it reads "No description, website or topics provided." Saves users from scrolling a bit.
This is common? Did the Biden admin halt all communications, grants, travel, etc.? NPR posts transcripts of their programs, do you have a link so I can see what they said?
Yeah if you chdir() in a multithreaded program, all cwd-relative file accesses in other threads are fucked.

As well as absolute paths, it’s ok to work with descriptor-relative paths using openat() and friends.
How many closing parenthesis do you have on a last line?
CDC probably does more public health? The work NIH funds through its grant process is not broadly "public health"; it's virtually all American biotechnology research and bio/biochem basic research. Public health deals with the interface of health knowledge and public policy and communication; people credentialed in public health are not, generally, practicing scientists as we'd think about them. NIH grant researchers, on the other hand, are wearing white lab coats and working with fume hoods.
As a result of RISC-V existing, all x86 processors have ceased to exist or be produced.
Trump has been pushing theocratic authoritarian bullshit for nearly a decade. It's what Trumpism is known for. It's what his supporters are known to support. We're not doing this historical revisionism now. This is exactly what people voted for.
so... smoking weed gets you the death penalty? Does that not sound like cruel and unusual punishment?
tl;dr: "do NOT meet the Title 20 requirement for a power factor rating of 0.7 or higher".
In other words, they are not efficient enough.

A cynical reader might conclude the company is grousing about the regulations.
There’s no question that the “war on drugs” sentencing is ridiculously out of proportion with the actual harm done, especially if you’re not white or upper class. I was making a comparison between types of financial crimes.
Health insurance is an entirely different animal. It has its own flaws and issues, as well as its own benefits. You can't easily compare a service product and an insurance product, they're just too different.

Though yes, financially health insurance also has no monetary value when anyone can get it for free. You can't assign a price to it and anyone in the health insurance business is entirely at the whims of what the government is willing to pay them to provide a service deemed essential enough to subsidize the entire cost of the product.
I have the same issue, I'm in an area with underground utilities so Sonic isn't an option, it's just Comcast or Monkeybrains. But the problem with Monkeybrains is that they had me behind a IPv4 NAT with no IPv6, and when I asked them to change that, I ended up with very bad packet loss that their technical support couldn't resolve.
Fair. But my intuition is that people do it until they get restricted by compliance, after which they seem to invest in a proper setup.
One pass, but.. I'm willing to bet there is some transitional internal state which had to be looped over to do this, subsuming the "pass" inside lazy eval. You have to know the indeterminate "where" to jump to, which depends on subsequent state. So you preserve execution state, calculate on, and return at end to fill in the gaps.
The impact of these travel restrictions is to cancel/delay grant review meetings, which could plausible "fuck up the NIH grantmaking process".

However, grant review can really be done remotely. And there are many other embedded inefficiencies in granting. For example, when my PI and I applied for an R01 (the basic individual investigator grant that is core to funding early investigators) we had to print a 500 page application which contained duplicate data, full CVs, pages and pages of boilerplate, and fedex it to NIH where it sits in a room with all the other applications (it's been 20 years; maybe this doesn't happen anymore?). The review committees instead get a digital copy and the grant meeting itself is really just a bunch of people sitting in a circle making yes/no decisions.
I also unhooked from Reddit when the API changes killed the 3rd party apps. Was a helpful motivator. Only use it now when it comes up while searching.
It could be much worse. Some parts of Onlyfans picked up the mantle for that sort of "service".
The travel part makes sense to me: as HN is pro-remote-work they should understand that these researchers can simply make their presentations via tele-attendance. The rest of the "refrain from releasing anything until a Presidential appointee can look at it first" seems very commissar-like. The HHS screwed the pooch on COVID, making a lot of nonsensical claims that ruined the reputation of public health in the population's eyes. I still don't like the idea of the Commissar reviewing every paper on bird-flu (our newest epidemic) but I can see the motivation.
What do those CPUID VM checks do anyway?
Interesting. How do the users connect to it? Do they tunnel into it or is there an application that acts as the proxy?
It doesn't look like, it is. e.g. violent coup and Nazi salutes during inauguration. Are people expecting the rise of authoritarianism to look different or something? This is the exact same fascist playbook that's been run every time. I really thought WW2 would have taught humanity as a whole the lesson but apparently not.
People love that line, but is it true? The premise of this freeze --agree or not-- is that the U.S. Government spends too much.

Or are you suggesting that this is to get back at NIH because of Fauci?

Or, are you saying that Republicans hate cancer research, or...?
Thank you for your suggestion. I made this to solve my personal problem of generating pictures when writing blogs and social media posts.

I also considered using AI generation tools to generate similar pictures, but they were all unstable, so I only made this tool.

Currently, this tool does support fewer templates, and the effect of generating copy depends on the template. Do you think it is a good idea to add some different types of templates in the future, or use AI to select templates?
> Well, that still wouldn't reduce your car speed by 50%.

It does actually. It limits your top speed, and your engines rev range to approximately half of redline or less. Typically you end up limited to under 45. Also, accessories and other options, like A/C are disabled. The only indication that you will get is the reduced performance and the check engine/service light (sort of how you might get a 'service battery' warning and reduced performance on a phone).

Again, not defending it, but pointing out that Apple hardly invented artificially limiting performance behind opaque warnings to prevent unwanted outcomes. Cars have had limp mode since before the iPhone was invented.
I truly appreciate your encouragement. I can only imagine how successful you are! Thank you!
The point of Chesterton's fence is that the fence was created for a specific reason and then was removed without addressing that. Replacing that fence with something built for an entirely unrelated purpose isn't replacing that fence. The closest equivalent would be replacing an electric fence with a small stone retaining wall.

They do different things. The electric fence is for keeping animals in/out and the retaining wall is for keeping soil from moving. Sure you may add the retaining wall but you've still removed the electric fence so the foxes can now get into your chicken coops or your cows are running free. That's chesterton's fence. Even if well meaning, making a change that fails to replicate/fulfil the original purpose of the original fence causes the issues to return.
that's the propaganda talking to you.
I'm with you but I'm also thinking about how I didn't even see the capability we have no being as close as it was 10 years ago. In 2015 I would have guessed 2030 or beyond.
I think something like a very public, televised shaming of researchers found to be fraudulent. Furthermore far, far more done to catch fraud before it is published, like bounties paid out, and instant career destruction to the fraudsters.

There was decades of “but everyone is doing it!” in the system, so much so that fraudsters became presidents of Ivy League institutions. The reckoning has not come.
Yes, I share the concern this article relates and hopefully saner (conservative) heads will prevail on the administration not to jank this up further. What I really want to do here is defang dumb debates about whether operational efficiency and headcount cuts inside NIH proper are disastrous. They may not be, so long as the grants keep happening.
I don't know if they are more competent now. There are just fewer people willing to push back, and few to no guardrails in place for when the leader doesn't adhere to the usual governmental and ethical norms.
No, HHS does the vast majority of public health research in the US, which includes both CDC and NIH. The CDC budget is roughly a quarter of the NIH budget; most public health research is NIH-funded. The CDC is more operational- they take what is learned and apply it to prevention and treatment.
This is what I mean by how messageboardy this issue is.
>Every single person responsible for how the government handled COVID needs to be fired.

Where do you stop? Because the administration overseeing the start of it just got re-elected.
We just rehired the guy in charge…minor observation I’m sure.
>statistics that might be used to argue against Republican talking points are going to disappear

So, you're saying the WHOLE map will be drawn with Sharpie? ;-)
If this isn't what they were voting for, what did they think they were voting for? Did none of them believe that he would actually do the crazy shit he said he would? Did none of them pay attention to the insanity of his first term?

I have a simpler explanation: they all know what they were voting for, and none of them give a shit. It's the same as the mob cheering and applauding the sieg heil on Monday. They know it's deplorable and unamerican and they don't care. Because the only thing that matters is that their boy will stick it to the enemy.
Which part of the response? Vaccines and masking were effective. Or was there something else you were referring to?
> Maybe so, but also then everyone has a Harvard degree, which is MUCH MUCH better for society than a Harvard degree losing value is bad.

Is it your opinion that Harvard could provide the same quality of education to an unlimited number of students?

This isn't a right/left scenario, its logistics and market dynamics. Expanding access to a scarce resource means value of that resource goes down. A supply glut doesn't mean the product is any less useful, just that there's more for it so people will get to pay less for it.
More the latter! It's still a very charismatic text that I'm fond of, and it's of course also intensely quotable. But given its brevity it can only deliver so much.
Why do most people in this thread assume this move intends to politicalize the NIH? I don't think the administration thoroughly thought out the consequences of this decision, but that's a typical government move. Never attribute to malice that which is adequately explained by stupidity.
https://simonwillison.net/ , since I'm a skeptic avoiding the "OMG the singular is near" hype.
ARM would have been a better example because the amount of people that care about RISC-V is a rounding error compared to x86 or ARM.
Social nets are a thing.

Not particularly worried about anyone dying off. At least in mid to rich countries.

Bigger concern in those to me is what sort of existence it’ll be. State keeps you alive sure but I’d like to do a bit more than that
The best product manager arguments are around value. The majority of the time nobody can justify the value of implementing their ideas, economic or otherwise.
Took another look at the connection info and yeah you're right. The Xfinity connection in my area is cable. Not sure why I thought it was fiber.

Thanks for the correction.
I don't know if I'd describe the approach as dogmatic so much as deterministic. Live patching is certainly faster than the alternative, but you have to make sure you e.g. restart services when the underlying libraries get updated, as one example. Otherwise a naive vulnerability scanner might see that the OS package for e.g. openssl is up to date, meanwhile the version loaded by nginx, which is now removed on disk, is vulnerable.
Demodesk (YC W19) Is Hiring a Ruby on Rails Full-Stack Engineer
What is possible though is a form of actual resistance. There is nothing forcing us to just share a union so to speak.
What is this "built-in WebView primitive" that Linux distros ship with?