skysight-inc/HackerNews huggingface dataset:
Sorry, I had it set to Canadian loonies and got inflated numbers.

Economists assume utility of money is logarithmically proportional to the amount, so losing a certain % of one's wealth hurts the same at every level.[1] Nadella made $84 million and is worth $1.4 billion according to the internet. For a $20k pay cut to hurt the same as a $5 million one, you'd need to have a net worth of x where (5000000/1400000000)x=20000 -> x=$5,600,000. For a $2772 pay cut---which is 6% of the median US salary---to hurt as much, you'd need $776,000 in wealth.

The median net worth is actually more like $192,700. So Nadella would have to give up (2772/192,700)*1400000000=$20 million to feel the pain of the median American giving up 6% of their income. That's quadrice what he actually did give up, but it still wouldn't result in his TC declining, since his pay rose by $30 million this year.

[1]https://economics.stackexchange.com/questions/23952/is-the-u...
It’s a form of evolutionary cross-tolerance. The mechanisms that tardigrades evolved to handle the hydration/dehydration cycle in moss just happen to be very effective at protecting them from radiation and a bunch of other environments.

That’s not a very satisfying answer until you dig into the biology that makes it happen. The mechanisms that protect cells from environmental stress are useful for many different kinds of stressors.
It's because our culture is set up to incentivize being weak and fat. You get up from bed, walk to your car, drive to the Dunkin Donuts drive thru, then sit in an office, until you go home.

It's insane to imply this culture just needs some drugs to be healthy.
My conjecture: they already had their process dialed in at Asian fabs, hence no need to re-configure or tune the machinery at Arizona which could lower the yield for whatever reason (leading edge CMOS truly is finicky).
Or they bought a new, refined version of the equipment.
It’s a shame I can’t speak polish, it’d be interesting to hear the results of the experiment.
The AI integration I'm looking for isn't to make chatgpt like queries or generate images or find one of my pictures, but to control my damn phone at a much more granular level. Settings are often getting removed or hidden or moved around to the point where controlling your device is a nightmare. Some examples of deeper configuration I'd love to see available:

- "Hey siri, stop interrupting my audiobooks and music with Teams notifications."

- "Could you please tone down the number of audio GPS alerts you send me? I don't need to be told five times before an exit that my exit is coming up. You're interrupting my audiobook too much."

- "Why are you interrupting my audiobook again?"

- "I don't know why soundless gifs keep stopping my audiobook, will you cut that shit out?"

- "Please let me use this audiobook app concurrently with this other app which has all sounds muted"
Safe C is harder than safe Rust.
Me too! If anything, iPhone photos became more over-processed over the last decade.
The study says only the oxidized Fe(III) ions are harmful.

Most iron in food, except that from blood or red muscles is in the form of reduced Fe(II) ions.
> almost as if they are testing the waters to see what they can get away with.

I think if it's a pattern then it's no accident. Of course people will test things. Kids, dogs, it's all the same: if you can get away with something, why not do it?
The drivers cut covers the capital cost of the car, maintenance and fuel. Not just labor.
So I agree with all of this, but will add we do know the long-term effects of obesity, diabetes and a host of the other things it is showing some potential signs of helping with. And because of the serious damage being done by those issues ([0] heart disease is the leading cause of death in the US), it just needs to be good enough to help resolve those issues without introduction anything too major as far as long term side-effects.

This is all to say, because of the current state of health norms (at least in the US), it just has to not do too much damage long term and the pro's can still outweigh the con's of its use.

[0] https://injuryfacts.nsc.org/all-injuries/deaths-by-demograph...
What I’m afraid of is that this just ends in an arms race of ever unhealthier lifestyles versus medication to counter-balance that. These aren’t wonder drugs. People just need to stop eating garbage food, and too much of it. And the government should pass laws to facilitate that to counter lobbyists
They don't support an unhealthy lifestyle any more than a miracle pill that stopped a harmful drug addiction would. Would you oppose its release since it's not actually "natural" to use medicine to stop your addiction, when you should instead use pure willpower? This simply doesn't make sense.

We live in a world of enormous abundance, exacerbated by companies min-maxing foods to have the most addictive properties humanly possible, at cheap prices.
That's true.

You may always need to keep one or two guys in there but they will be able to do 20x more with the same effort. Definitely plausible.
If we can alter the chemical composition of peoples brains/guts to make them less hungry, how long until something similar exists to overcome anxiety? Public speaking fears? etc.
This can't be right. I've been hearing about how great AI is for the past year now. It couldn't be that media outlets just report on whatever they think will generate the most revenue.
My response it motivated by outcomes, your response is motivated by an extreme devotion to far-right ideology.

We both understand that such rulings undermine democracy and are detrimental to our country as a whole. However, that is what you want, because you are an extremist. You merely pretend to use law as a cover, when in reality you're jumping at any and all opportunities to undermine democracy.

There exists not a single reasonable person who believes giving large, powerful corporations the power to influence elections is a good thing. You know, and understand, that is a bad thing.

I do not care if the "law", as you understand it, promotes bad things. They are still bad.

In addition, before this ruling and others the opposite has been argued. You, too, are not participating in "careful and objective study of the law". We have many, many years of legal precedent being overturned here. Why, then, does that precedent not matter?

Please, drop the facade of objectivity because I don't care. Either say what you intend to say or do all of us a favor and stay silent. I grow tired of those so ashamed of their own beliefs they dare not speak them.
This is exactly right. Let the market decide. If people want to use new experimental drugs, why not let them have at it. They oughta be responsible for their choices
It's so weird to me that with a vaccine against COVID the populace was going all conspiracy theorist. Saying the longterm effects are unknown etc. But with these kind of drugs there are suddenly no issues.
Ceci n'est pas un submarine.
See this paper by Geoffrey Kron which shows later studies (some of them by the same authors) in which adult males from classical Greece were about as tall as the dead men from Tollense battlefield https://www.academia.edu/361745/Anthropometry_Physical_Anthr... That chapter in "Men of Bronze" was written by someone who started with a conclusion and cherrypicked anything which seemed like an argument for it.
Its being celebrated because it is an amazing development? I think I can agree that, ideally, people will bootstrap healthy lifestyles and not need the aide long term. I don't know how you could justify that as a reason not to be glad the aide exists, though?
Existing contracts aren't structured as a lump sum they can just tack on some margin for and dealers don't fully control their margins. There's half a dozen "incentives" that are given as percentages of sale price plus whatever additional fees they can throw on that need to equal that margin. It's not that these are impossible problems, but they require coordinated action in an industry that's full of mutually hostile parties.
what I showed is the squared 4 momentum when you use the Minkowski metric [1], assuming "squared" means "self-dot product". The formulation above is just another way to illustrate the Minkowski dot product.

[1]: https://en.wikipedia.org/wiki/Minkowski_space#Minkowski_metr...
Maybe an archaeologist will discover your phone in 1000 years, and lo tests will confirm that it came from China!
Zig is easier than Rust.
Oh I'd love to, and I did for years.

The problem is using 99% of third party libraries without building has become nearly impossible.
This medicine literally aids people to become healthy. They will gain years of life from the lost weight.

Their lifestyle changes to be healthier by eating less, which many are unable to do without help because the human body has millions of years of baked in evolution demanding we overeat if able
Think I generally agree with your sentiment, but my understanding of how Ozempic works is that it kills your appetite. The "unhealthy lifestyle" you're referring to is one of overeating. Ozempic doesn't support a person to continue overeating, it removes the desire to overeat. From that perspective it is aiding people to become healthy.
Not trying to argue, more just curious, what drugs are you referring to with this comment?
>"People just need to stop eating garbage food, and too much of it."

Easier said than done. However for the vast majority of the people taking these drugs, these drugs enable them to finally do that.
Brainfuck is turing complete, why would we worry about any other structure preserving compilers? Brainfuck will do just fine /s

CT is outside most problem domains in computation, as its outside the time and space constraints of a machine. Knowing whether a program will never finish is part of CT for software developers. So handling this case is a maybe in CT while it's a must in software (running endlessly means crashing).
I wonder if all these other 'bonus' effects really just stem from the same root cause which is effectively food that is just really bad for us. So if you eat less poison, you get a lot healthier - not just slimmer.
Yet another Lasalle anecdote:

> ...j’espérais remplacer le général Dahlmann, colonel de vos guides. » L’Empereur répondit : « Quand le général Lasalle ne jurera plus et ne fumera plus, non seulement je le mettrai à la tête d’un régiment de cavalerie de ma garde, mais je le ferai un de mes chambellans. » Le général Lasalle s’inclina et dit à l’Empereur : « Sire, puisque j’ai toutes les qualités d’un marin, je demande à Votre Majesté le commandement d’une frégate...

(Lasalle hopes for a promotion, but the Emperor tells him if he quits swearing and quits smoking he'll not only get the promotion but become a chamberlain as well. Lasalle responds, "As I have all the qualities of a sailor, why don't you put me in charge of a frigate?")

More seriously, today I learned two ways to say "legacy code" in chinese, of which I suspect 问题代码 to be more polite, and 屎山代码 somewhat less.

Poking around in https://zh.wikisource.org/wiki/三民主義/民權主義第五講 I found another trichotomy, just a little less cynical than Rao's:

SYS Gervais SYS example
------ ----------- --------------
先知先覺 psychopaths civil engineer
後知後覺 clueless foreman
不知不覺 losers workmen

Not being a fellow of the AEI, 孙逸仙 argued for wide allocation:

> 都是靠這三種人，無論是缺少了那一種人都是不可能的。... 先知先覺的人要有一份，後知後覺的人要有一份，就是不知不覺的人也要有一份。
Humane bets others need its AIOS
Discussion (18 points, 14 hours ago, 14 comments) https://news.ycombinator.com/item?id=41942007
This is a drug that literally turns off the part of your brain that craves overeating. Governments can’t legislate against human nature, as much as the nanny state wants to. We fixed food production without fixing the scarcity mindset that got us here. Now we’ve fixed that too.
I realize obesity is a major problem, but so is neuroticism about health, weight, and diet. I agree with the nagging feeling that using a drug to address hunger is likely to have negative consequences for some people.

EDIT: obsession -> neuroticism
Just as well as it could be “less bots” promoting one side, to “more bots” promoting the other. What types of war would you not consider a crime?
I would kinda like search that works over my thousands of photos
I don't oppose the use of this drug or its release. People should be allowed to do what they will. I see harm in celebrating the drug as a cure to obesity. Of course, certain diseases may make it easier for you to gain weight. Though obesity is not like cancer, it is a condition brought on by unhealthy behaviours
Worked for me. On Firefox if that matters...
Safe Zig is harder than safe Rust, but easier than safe C.

In conclusion, programming is a land of contrasts.
Yeah as long as you're not chewing or extension cords you should be good.

The most common water pipe in new construction is cross linked polyethylene. XLPE. It is stable, inert, and contains no plasticizers. PVC is often used for sewage drain pipes. Like the parent said it is the rigid crystalline kind typically containing minimal plasticizers tightly bound within the crystal matrix.
Wait a sec. Something which provides such an unambiguous quality of life upgrade by addressing one of the biggest health problems in the country, is only now available because of regulations?

Surely it's not that simple.
Not how it works. Ozempic seems to shift processes in the body that divert you from the unhealthy lifestyle
https://archive.ph/hz4t2
Oh you just done a heckin double badspeak. Not only are you not trusting my science, but you're slandering my big pharma. Big mistake. Thats a downvote.
That’d be useful but I’m pretty sure they’d get a massive backlash on Fox News and lawsuits filed alleging “being cancelled” within minutes of that shipping. It’s something we need but our current disinformation problem isn’t an accident but the result of decades of investment.

The less fraught one is warning users that they’re being scammed:
https://arstechnica.com/gadgets/2024/05/google-wants-ai-to-l...
That's just not true, knives are quite effective self defense tools that allow otherwise physically weaker individuals to inflict significant harm on attackers without much of any additional risk. I know that in the movies this isn't true, but that's just not a reflection of reality.
Meth and cocaine (and cigarettes) were all touted as weight loss drugs in the past before they were made illegal.
I guess it's because some of us aren't as perfect as you.

If humans stopped eating sugar we wouldn't need most dentists. Should we stop celebrating dental advances?
...and that is a terrible thought for me.. 'thinking as the second best option." I guess we need to think through carefully many processes, and then allow the 'tools' to do the jobs for us... but then are we simply adopting these tools and losing the ability to think? As a simple example - Smartphones have many advantages, but we used to have to hold a host of telephone numbers in our heads and then think as we dialled the numbers (or read them from our little address book), GPS has helped in so many ways, but also hinedred our ability to think of routes, as I said simple examples. Some tools are dosed out to us without our thought, we adapt rapidly. As you said about search - library research at uni's is dwindling dramatically. We do give up a lot for the convenience of tools - and it will continue as we 'automate' more. So, we need to use the time we gain wisely and become discoverers... seeking new knowledge, rather than letting, mindless screen time become our daily norm!
Sorry, I thought it'd be obvious that all those -ough words have different pronunciations (for most people, anyway, I think) and that I'd be making my point clearly and lightheartedly. I was just saying that English spelling isn't always "guessable", or how you think it logically should be. [Even though it may well be guessable the majority of the time, as another responder points out, for some reason].

The fact you think "busses" is a preferable spelling to "buses" because it might help you pronounce "buses" differently to "fuses" is only relevant to you yourself. I would have thought this was tautological, myself.

In summary, we could avoid all these fusses with a bit of effort to adhere to accepted usage.
Was this posted to highlight some marketing gimmick on crackers? I'm not sure why it's considered relevant for this site.
Their slogan in Arabic is "from the river to the sea Palestine will be Arab", the river and the sea are the borders of Israel and its tantamount to "kill all the Jews".

There are many variants of the slogan of course, but for some reason you're picking one of the more uncommon (and more virulent) versions. However, he "official" versions (for example from the PLO) use the phrase to call for a single democratic state for Arabs and Jews, that would replace Israel, and from which nobody will be expelled.

This is of course also in line (albeit in somewhat simplified form) with the version one sees almost uniformly on the streets these days, "From the river to the sea, Palestine will be free", and if you ask people what they mean by that, most of them will tell you something equivalent to the PLO version.

Meanwhile since 1977 Likud has used essentially the same slogan, but in reverse, minus any aspirations of democratic equality, and with racial supremacy baked in: "Between the sea and the Jordan there will only be Israeli sovereignty."
It's called alcohol
Will do, thanks paul big fan of your work
What to expect from Apple's 'week' of Mac announcements
My father has used ozempic. He hails it as a wonder drug, yet he does little to nothing to change his behaviours because he can rely on this crutch. I see that as concerning
Hi, I'm Mergen and I work on ExecuTorch.

ExecuTorch is a runtime for mobile and embedded devices to run PyTorch models directly. Currently it runs pretty fast on CPU, but expanding our use-case for mobile accelerators and GPUs.

We're still in our early stages (just turned beta status). But try it out and let us know.

Regarding Llama Stack, it is built by my colleagues. What were some concrete issues have you experienced? If you have error/bug reports, I'll happy to pass along.
> I realize obesity is a major problem, but so is obsession about health and weight.

The scales of the two problems are not even remotely comparable.
Coming from a position of extreme Rust ignorance & C++ brain poisoning:

Here’s the issue: waiting_for_elements is a Vec<Waker>. The channel cannot know how many tasks are blocked, so we can’t use a fixed-size array. Using a Vec means we allocate memory every time we queue a waker. And that allocation is taken and released every time we have to wake.

Why isn't a structure that does amortized allocation an option here? I appreciate the design goal was "no allocations in steady-state", but that's what you'd expect if you were using C++'s std::vector: After a while the reserved space for the vector gets "big enough".
The answer is Ozempic seems to do this already.

My theory is that something goes haywire in the body and causes many issues. Obesity being the most visible of these but far from the only issue.

GLP-1 agonists reverse this thing that went haywire and fix many issues

https://www.medicalnewstoday.com/articles/weight-loss-drugs-...
Thyroid cancer sounds more scary than it actually is. It's one of the weakest forms of cancer, and it's extremely easy to treat if caught early enough. Also, living without a thyroid is no big deal.

Somebody very near and dear to me was diagnosed with thyroid cancer ten years ago, and now has no thyroid. She's hardly inconvenienced by it & hasn't even gained any weight since then. Just gotta remember to take those T4 tablets in the morning, is all.

Point is: If you weigh in the balance [lives saved or QALY gained due to GLP agonist administration] vs. [lives lost or QALY lost due to thyroid cancer secondary to GLP agonist administration], it's not even going to be remotely close. "Lives saved" will probably win by an enormous margin, maybe a factor of twenty or so.
I think you're overestimating your knowledge of what causes obesity.
It's a pretty dangerous mindset to imagine you're "fixing" a problem rather than "treating" a symptom.
Shouldn’t we have a non-negligible prior on possible cancer risks at all timescales? That doesn’t mean we don’t approve drugs without 80-year clinical trials, but I think it’s a non-negligible risk that has to be accepted.

For instance, my impression is that lung cancer rates only really become strongly pronounced — in the sense of being statistically detectable in the small population sizes you find in clinical studies, rather than the entire US population — after like 15 years of smoking. (Correct me if I’m wrong.)
Why is this being celebrated?

Call me cynical, but maybe because Big Pharma has the deepest pockets and is one of the largest (if not the largest) spender on advertising out there.
perplexity ai on top ngl
I don't know of any Flutter comparisons, but we shared some benchmarks here: https://github.com/reactwg/react-native-new-architecture/dis...
But this drug is basically mind controlling people to live healthier. Its not countering an unhealthy lifestyle, it improving their current lifestyle
Wow they announced this back in May and it's still not available for me.
Retrieval Augmented Generation (RAG) App for txtai
I can't read the article but I have kept up with the almost daily revelations about this class of drugs so I have an idea of what its about. I am truly hopeful for the kinds of society wide changes it promises to bring about.

We seem to be rapidly approaching an inflection point, brought on by the compounding distributors such as Hims, that will need to be resolved: there are probably more people on the compounded version of this drug than most suspect and that number is growing by the tens of thousands every day. Meanwhile, Norvo Nordisk is trying to shut down this channel of distribution. That would be a bad idea and I think the FDA must be aware of that. This conflict between NN and the compounders needs to be resolved.

Personally I think the promise of this drug makes it a moral issue and have little sympathy for NNs position here: they will need to capitulate on their control over it and accept some kind of suboptimal pricing agreement. The potential positive outcomes of this drug supersedes their sole claim to it IMO.
This has 10+ years with tons or people and studies over the side effects. Not to justify the the conspiracy theories, but it’s not apple to apples
I don't think this is true at all. Peoples' obsession with solving obesity as a cure-all for human health deserves pushback. There's also a concerning degree of moralizing it that has no place in our culture but has taken firm root.
> is there a way to reduce complexity here?

Yes, you can generate your test data in the host language. That dramatically reduces upfront complexity.

But that doesn't come free. Now it is not easily transferrable to other languages. If you recall rsc's somewhat recent talk on testing, they benefited greatly by being able to use similar DSLs from other projects in tests to ensure feature parity. It can be a huge boon to have your test data scripts in an "agnostic" language for 30 years down the line when you are no longer working in the same environment.

Tradeoffs, as always.

> I was expecting more than a few real world use cases

Maybe that's the only use-case they know of? The project was clearly built for a specific purpose.

That's not to say that it cannot be found useful elsewhere, but that doesn't mean they have found it to be. If someone else finds it useful in other applications, I'm sure they'll write their own document about it. That's what the web is for, after all.
The main theory is that it actually came to Venice from the sack of Constantinople. Which would make a lot of sense: placing proof of your military power in your main square is something that people would do, and the Eastern Roman Empire probably had more regular contacts with China over the centuries.
Why would you trust AI, something that regularly makes stuff up, to be able to accurately determine that?