skysight-inc/HackerNews huggingface dataset:
The problem is not the drugs, themselves, but rather what they are used to treat: short-term infections. Compare this to things like statins (cholesterol drugs), which are almost always used for the remaining lifespan of the patient. Then consider the primary affected populations. Poor populations (with poor sanitation, access to clean drinking water, and regular health care) that have little disposable income are going to be the major consumers of antibiotics. High cholesterol, on the other hand, is a disease of the affluent.

So I think the article is wrong that extended patent protection will lead to more antibiotic abuse. Pretty much any short-term market approach to antibiotics will lead either to their over-use for marginally reasonable purposes, or simply result in less investment overall (compare the number of new antibiotics to the number of new statins over the last 2 decades).

No, antibiotics (and bacterial countermeasures in general) seem to me to be more amenable to an insurance approach. Most people don't expect to die in a fire, but they do spend money on the possibility. Most people, similarly, don't expect to die from a bacterial infection. Today, that means they don't spend any money on the possibility. That needs to change.

The challenge, of course, is that when the shit hits the fan, good luck justifying not providing antibiotics to people who didn't pay their "premiums". So, really, you need something like car insurance, where everyone (and here I also mean every country) is required to buy in.
Indirectly he can. If he choses not to sign new laws.
Neal Stephenson's Epic Fail
I'm not talking about a category of employment as in "delivery driver," I'm talking about a category of employment as in "jobs accessible to bottome 50% of people." If relative wages are declining in that category, it's hard to make a case for increased prosperity, unless you're just talking about the other half, or about increased work hours.
I disagree on the offensive party part - in Feb 2012, Google/Motorola used a pager-era patent to get an injunction against multiple Apple devices[1] in Germany. Apple had to disable iCloud push email feature to get their products back on shelf.

[1]http://arstechnica.com/apple/2012/02/apple-faces-double-wham...
The problem is that just as there's a lot of room for interpretation regarding whether something falls under a certain software patent or not, whether something get ruled as valid prior art by a specific judge is likewise a crapshoot.

Secondly, IANAL and I might be mistaken, but I'm under the impression that the current case is solely about whether Samsung violates the patents or not. The validity of the patents themselves would have to be argued in a separate court case.
Apple fans supporting Apple's anti-competitive practices? Sounds hypocritical to me. You exaggerate, I exaggerate, everyone exaggerates!
on reddit however...
I've owned two MacBooks, a MacBook Pro, and two iPhones, but I won't now. No more. I had no particular reason to want to boycott them then before because they weren't behaving atrociously at that time. The kind of person who would boycott Apple now is the kind of person who would have boycotted Microsoft back in the day, which also happens to be the kind of person (or one kind of person) who would have bought Apple products.
There will always be new targets for new antibiotics. That's not the problem. The problem is that we started, with Penicillin, by picking off the low-hanging fruit. Now the bacteria are playing an impressive game of catch-up. Soon, the speed with which they will be able to develop new resistances will overtake the speed at which we can develop new antibiotics. (Also, more potent antibiotics are more likely to have nasty side-effects.)

The good news is that the Russians have already done a great deal of work toward the post-antibiotic era by working on bacteriophage therapies. Bacteriophages are the long-term end-game to keeping bacteria in check, since they can be made to evolve at the same or faster speeds than bacteria.

What is needed now is more research into bacteriophages, and much, much more research into Evolutionary Dynamics, so that we have some clue what is going on (and so that we can better predict the future development of resistances).

Of course, it's kinda hard to do research into Evolutionary Dynamics when the richest country in the world has political leaders that still question the validity of evolution...
I hate it, because if I were to use it, I couldn't make a weight watcher app (I don't need or want to lose weight), I couldn't make an app to help women keep track of their period or when to take their birth control pills (I am not female).

But neither of those are evil, and both of them arguably improve the lives of their users.

As for how to balance having a conscience, that is easy as you need to find a product that you believe in and then you won't have moral issues with causing more people to use.

If you can't find one, then realize that there is no god, no universal morals and what we believe is right or wrong can be changed. If you simply believe that you are a moral person and that you don't do things that are unethical then cognitive dissonance will ensure that you don't have any issues with you conscience.
Also -

C/C++: http://erlang.org/doc/man/ei.html

Ruby: https://github.com/mojombo/erlectricity

Java: https://github.com/fredlund/JavaErlang/
First look at India's 2nd-generation, USD $40 tablet
Walks And Walking - Wales Walks Coed y Brenin Forest Park Snowdownia
This post is great but it speaks primarily to B2C.

B2B market will still be desktop/web based exactly because of the mobile apps being more features than actual applications.
> but this is business and we people should just let it play itself out in court.

I'd be okay if the patents in question were not trivial and something really innovative(like RSA).

Also, consumers should make decisions based on their convictions too. For example, I shop at CostCo instead of Sam's Club because CostCo treats their employees much better than Walmart(which owns Sams) does.

"Be the change you wish to see in the world." - Gandhi
What worried me most is that SSDs with the apparently current 22nm size have only 2k/3k write cycles, where older ones had 10k. Seems a bit low to me.
Seems nice. Last commit was almost a year ago though.
Tl;dr: 20% Cheaper, double the processor speed, capacitative touch-screen, nifty built-in development environment, longer but still fairly sad battery life, and meshuggah old-school socialist distribution policies.
True, but developers are more likely to care, and they matter a lot more than the average user. A lot of developers preferred not to use Microsoft products when MS was the evil empire, and there would probably be an MS monopoly now if they hadn't.
I am somewhat disappointed by this text it claims to be on how to manipulate people but is in reality a morality story (which I could have gotten in the local church if I wanted it).

On the other hand, I do enjoy the irony.
> And real manipulation and persuasion seem to fail: if everyone is allowed to manipulate everyone else, everyone loses their own control of themselves -- in which case, how can they manipulate someone else? There is a contradiction.

Consider the case of two people A and B in a zero-sum game, who are trying to manipulate one another. Both parties know the score---that each is attempting to control the others actions.

When A or B acts, either one party has succeeded at manipulating the other or both parties have failed.

There can be no situation where A manipulates B (thus A wins), and B manipulates A (thus B wins simultaneously).
VMware launches Project Serengeti to make Hadoop virtual-aware
Download You Tube video and do more using Extend Tube Opera add on
http://en.wikipedia.org/wiki/1-Wire

Probably not used in headphones, but it could be.
Yeah, I've been using that one for some days already. It's really nice but not what I really want. :)

For example I can't hit tab to auto complete. I'm also missing all the zsh awesomeness, so a real terminal running in some tab would be the best solution!
Seems to fall apart at a close look.

Except at the extremes, "materially improves users' lives" seems highly subjective. You can make this fit almost any product with a clear conscience - so no one's going to describe themselves as a Dealer or Entertainer.

Also, creating something you personally would use also seems like an odd and arbitrary distinction. I doubt patio11 is personally running many bingo games - but I'm certainly not going to criticize him for building a product many other people find useful.
Titan: Hide methane water factory in the Universe?
This is super short sighted. There are billions of people in India/Africa combined, it doesn't matter that they can't pay that much individually because combined they represent a huge and growing market. So what you say might be true today, but it's not a good long term strategy. These are exactly the kind of markets that people should be targeting, uncrowded and huge huge potential
The fact that "Tech companies sue each other and get import bans all the time" doesn't strike me as being "a non-issue". It's strange that your summary of said "non-issue" comes across so negatively.
If you actually used Reddit you would notice that most ignorant and outright trollish comments are downvoted into oblivion. You see a lot more awful comments, but that's only because Reddit is larger. They're treated the same.
I am sorry, but given your submission history I find it hard to believe that you are not aware of the fact that Apple started suing Motorola in Germany first.

http://www.fosspatents.com/2011/08/apple-is-also-suing-motor...
Especially as the people you are aiming your thermonuclear weapons at happen to be part of your supply chain (or trading closely with them)
Show HN: My first iphone app was accepted
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Ah, I was just going to say, "the only downside to this story is that the charity now gets $1K instead of $1M" :-) But not even that is the case.

Indeed 100% class.
Rise Of The Enterprise “Toys”
> Every single comment would be downvoted to oblivion if it were posted here.

Well, after reading the comments in this thread here, and some of the comments over on Google+, I'm gonna have to say you got that prediction wrong. =)
A lot of people will suggest Django, and it's definitely the most popular Python web framework (and therefore the most useful if you're looking for a job using one). However, Flask is written in a much more open-ended way that gives you a lot more power to create the structure of the application as you see fit. I've been working with it lately, and I'd suggest giving it a try.
It is appealing to see a down-voting complaint for an unpopular opinion related to a comment which dismisses a trend on Google+ being irrelevant because the network is relatively unpopular.

I doubt the 75 million people who use Google+ consider themselves a "very limited audience."

Regardless, not a reason for down-voting.
Something about Koh's overwhelming bias for Apple seems really suspicious. It's one thing to preeminently ban sales of product A for reason X, but to also ban sales of product B for reason Y where products A and B have the same parent, and where reasons X and Y are completely unrelated? Something is wrong with this picture.

What else could be going on? Maybe I have a cynical view of humanity, but I spent a few minutes digging to see if I could find anything on requirements for District Judges to release tax returns (as they are essentially public officials, right?). Couldn't find anything on that, but generic salary data is available: http://www.fjc.gov/history/home.nsf/page/js_3.html

$175K is probably rather low when you're used to working in the high-stakes world of patent litigation.

It'll be interesting to investigate this with more depth. ( Another interesting / related read: http://articles.latimes.com/2009/sep/27/local/me-judges-pay2... )
Get a job and save your money? Man, I wish I had a downvote button.
Having unstructured social time should be one of your goals too!
just use cygwin
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OWC sell an upgrade for the Air's SSD, I imagine it's just a matter of time until there's one available for the retina pro http://eshop.macsales.com/shop/SSD/OWC/Aura_Pro_Express
Console2 regularly crashes on my Windows 7, and it looks like it's not actively developed.

I'm giving ConEmu a try and it looks awesome!

http://code.google.com/p/conemu-maximus5/

Scott Hanselman wrote a blog post about it:

http://www.hanselman.com/blog/ConEmuTheWindowsTerminalConsol...
In India probably even a $200 Nexus 7 is considered too expensive for most people, but I can't help but feel that in the long term they would be better served by at least a $100 tablet (like Novo7) with the latest version of Android (this one is still running Android 2.xx), and with a battery that can last at least 8 hours turned on, so the students can use it all day in class. Why bother making a tablet for students that lasts only 3 hours and is still pretty slow?
Your Last Password | In Depth Look
I feel like cygwin manages to combine the worst of UNIX and the worst of Windows. And the commands that use the cygwin runtime are noticeably slower than the native counterparts.

Also, AFAIK there is no 64bit version yet, which for me is a dealbreaker (I often work with files larger than 2GB).
That's pretty impressive. If you don't mind me prying, how long did it to take to rack up those earnings (guessing 2 months since it was posted) and where did most of your traffic for that post come from (rss subscribers vs search engine referrals)?
Highly recommend Harumi Murakami's "What I Talk About When I Talk About Running" if you wish to read more inner thoughts about running.
All parties here are responsible.

As long as companies keep building up arsenals of shit patents that they can use to justify these preliminary injunctions, or shop jurisdictions, the beatings will continue and make it virtually impossible for new players to enter the market for fear of legal morass.

The issue in the Apple cases that makes me so angry is that they're treating the US patent system like the Japanese 'product design' patents, only impossibly broader and less specific.

This type of nonsense - both from non-practicing trolls and the hegemony of practicing patent trolls - has a real cost. Congress needs to step in and limit the scope on a broad swath of patents, make it harder to get injunctions on this stuff, and generally find ways to penalize anticompetitive behavior.
The R magic is going to be a real win. Great job.
RIM Is Dying Because It Got the Future of Phones Completely Wrong
I didn't buy my copy of Debian, yet they treat me better than many companies I pay.

I pay for cable, yet I still get advertising.

That "not paying means you're the product" is a nice sound bite, but it doesn't actually mean anything.
All the early adopters already have their Xboxes. The iPhone is lame and tired, and there was nothing at Apple's WWDC that had any wow.

For the moment, the fun stuff is coming from the Android ecosystem, and Apple is getting in the way of people getting it. Hence the wrath of the crowd who adore new things, the ones that Apple used to care about, before they crossed the chasm and jumped the shark.
I absolutely agree with you, given the choice and the ideal world, I'd much rather live in a fair system where companies compete on the things that actually matter. Absolutely.

I just think we're fooling ourselves if we think that we can simply expect people to adhere to this with no tangible incentive, rather than build a system which has the desired result.

In other words, it's still the system that's broken. There are a lot of companies I'd like to boycott (and I certainly boycott and disagree with Apple's decision on this specific matter), but I don't blame the companies for trying to make money—regardless of "fiduciary duty" which is pretty irrelevant (I was just talking about the nature of companies to make money and dominate the market if possible; this would be true of any company, not necessarily just public companies with duty to shareholders).

This is a tough call, and I'm sure it was tough even for Apple's legal team. Is it worth tarnishing their image to attempt to hold a competitor from the market for another couple months? Looked at from a strictly logical standpoint, with profits enabling more technological developments and more production capacity, as well as more advertising and sales efforts, it just might be worth it.

You know that a whole team debated this and did dozens of calculations and eventually the call was made, but knowing Apple, this was no butt-hurt matter of principle. This was a market decision based on something they could do that would be beneficial for their company in the grand scheme of things.

Do I agree? Not really. I think the company's reputation is way more important than this injunction. But it's an exceedingly complex decision, based on many factors that I don't have information about, and they made a different decision. I honestly can't blame them for that.

It's easy to answer my question with a simple "yes." It hurts you. It doesn't feel right. Companies shouldn't be so impersonal. They should play nice. I know. We need to fix the system that allows despicable acts like this. But in the context, it makes perfect sense. "Blame" is not addressable here except to the system. (As is usually the case, but that's for another essay...)
Microsoft's monopoly on computing lasted for at least 17 years, if you count from Windows 95. I think it's time for a change of leadership in the market. That sounds more interesting to me than 30+ years of Microsoft monopoly.
Siri in portuguese is crab. So the "People feel they are talking to another person" doesn't apply everywhere.
Fool.com has a bunch of tutorials (http://www.fool.com/how-to-invest/thirteen-steps/index.aspx) and some premium newsletters that can help you through this process. From what I can tell, there aren't a lot of simple alternatives to the big brokers. We do have a comparison table (http://www.fool.com/how-to-invest/broker/index.aspx) that covers the pricing and features of a lot of them.

Disclosure: I work there as a developer.
It's not like Amazon is making any secret of this: https://kindle.amazon.com/most_popular/highlights_recently

Speaking of which, I wonder what to make of the fact that 23 of the top 25 highlighted passages are from the Hunger Games series. Are they that much more popular than everything else in the Kindle catalog? Or are their readers just more likely to use the highlighting feature?
Help us find an international name for our startup
Hi everyone,

We're at a loss to find an internationally viable name for our online menu app, StamSted.

In Danish, StamSted means your 'haunt', 'that local place down on the corner' and that's what we're all about. Local menus, you can order directly from.

We're not sure if the the StamSted will be catchy/memorable in english.

We considered stuff along the lines of 'patronify.com' - but patronize is probably more about being condesending, than being a patron these days!

Cheers if you have any thoughts or ideas! :)

stoffr from StamSted.com, Denmark.
You should never have to press a button to take a page out of an unusable default state, but if that's going to be, the button needs to not be lost in a pile of clutter.
So, the takeaway is, "Damn, Apple is good at this capitalism game."
I am enough responsible, don't give me more responsibilities.
I do follow the patent law suites. In case of Apple vs. Motorola, it was in fact Motorola that set the ball rolling with its first suit in October 2010 in the US. It was the same fight over the same set of patents that has spilled over into German courts.
If relative wages are declining in that category, it's hard to make a case for increased prosperity...

I think you meant to say "if absolute wages are declining". Increased prosperity could easily make relative wages decline - the bottom might increase by 10%, while the top might increase by 20%.

But forget the bottom 50%, lets look at people below the poverty line. Even most people below the poverty line today have a house (with 2 rooms per person) and a car. And that house has all sorts of amenities that were uncommon even for the mid to upper classes in the 1970's.

http://www.census.gov/prod/2008pubs/h150-07.pdf

The numbers suggest the lifestyle formerly characterized as "middle class" is now accessible to virtually every American. I.e., we have more now than ever before.
Essential Ruby on Rails Security
What do you think of my new grammar and style checker?
I'm with you there -- I find Cygwin starts slow and unstable, and then seems to rot at an astonishing speed, to the point where it's usually unusable after I've had it installed for a couple of months.
Netflix knows how often I replayed the first 5 minutes of The Invisible Man, too. :) This is more concerning:

https://kindle.amazon.com/post/192I0Q7B1DRFJ

Apparently notes and highlights can be made public, with your name attached no less, and they are indexed by search engines. As soon as I saw that I rummaged through my Kindle settings (app on iPad, v 2.85) but couldn't find an option either way.
Calling me a pervert is redundant. All human beings are perverts. At the end of the day we just want to see attractive perfect human specimens naked.
Is this different from Unix Utils? Every gig I've ever been on where I'm forced to use a Windows box, first thing I do is load the Unix Util exes into some directory and add it to the path. http://unxutils.sourceforge.net/
1 month. Amazon takes a while to deliver payment, and I just got my first payment a couple of days ago. However, earnings went way down after the first month. This month I only made $17.

HN was the biggest source of traffic, followed by reddit. A bunch more came from twitter, facebook, google+, as people shared the article.
I assume it's because they're both popular and free to borrow via the lending service if you're an Amazon Prime member.

IIRC, up until a few months ago, the free Jane Austen e-books dominated the top highlighted passages.
For Twisted: https://launchpad.net/twotp/
I wish your statement about fiduciary duty were true. It's not a recent concept.

http://en.wikipedia.org/wiki/Dodge_v._Ford_Motor_Company

“The Court held that a business corporation is organized primarily for the profit of the stockholders, as opposed to the community or its employees. The discretion of the directors is to be exercised in the choice of means to attain that end, and does not extend to the reduction of profits or the nondistribution of profits among stockholders in order to benefit the public, making the profits of the stockholders incidental thereto.

Because this company was in business for profit, Ford could not turn it into a charity. This was compared to a spoilation of the company's assets. The court therefore upheld the order of the trial court requiring that directors declare an extra dividend of $39 million.”

The Wikipedia article notes that it's not considered 'current' law in the U.S., but this was decided in the early 20th century (~1920).
I don't understand this.

People in the developed world pay nothing for most of their online/mobile apps and experiences.

How is that different?

A tiny fraction of the price comes with a tiny fraction of the operation cost.

Also both India and Africa are regions on the rise with a growing middle class.

I don't believe you have really thought this through.
It's fun to think about but it wouldn't change Facebook's model at all. The power of Facebook is based upon the number of users it has.
Some of the decline is probably linked to the Pharo fork http://www.pharo-project.org/home
You could use the page visibility API to wait until the page is visible before loading the analytics code.

https://developers.google.com/chrome/whitepapers/pagevisibil...

This is only for prerendering. I think joshuahedlund is right about prefetching.