skysight-inc/HackerNews huggingface dataset:
In short, no. I don’t know about their effects on brain connectivity or other imaging characteristics, but the subjective effects are significantly different and the (mental) therapeutic effects come from neuroplasticity being induced, which is independent from NMDA antagonism[0]. This is likely why ketamine (and analogues) stand out as treatments for depression and other conditions.

[0] https://www.nature.com/articles/s41380-021-01121-1
Tech companies inflate roles, especially in sales teams, so that enterprises think they're talking to someone important, when in reality it's just a dude with his second job out of college. Same with Investment Banking Vice Presidents (although IB VPs will definitely have the experience to back it up, if not the authority in a deal).
They did. But things slip, machines fail, etc.. it is quite insidious.
Inflammation is part of the immune response. It’s generally a good thing if it happens when needed and if it stops when the stimulus is gone. If your immune system is stimulating inflammation for false positives or continuously that is when damage can occur.

Next time you think about consuming a product that claims to boost your immune system, ask yourself if you really want to increase your chances of inflammation or not. they are two sides of the same system.
Maybe that’s one way to retain engineers who are effectively millionaires.
I could be utterly wrong, but I suspect part of this is that applying for jobs has become so quick and easy - a button click - that entities advertising jobs are utterly swamped with utterly worthless applications.

It's a bit like email spam - I remember back in about 2000 and something, before I sorted out my own email, getting literally ten thousand plus spam emails per day.

Imagine the same, but it's CVs, and somewhere in there might be a couple you care about.
'PhD influencers' logging lab life on TikTok and Instagram
>Alcohol is suspected to be carcinogenic.

Everything is given high enough doses.
If only Elon was more like your average commenter on HN, just imagine what he could have achieved then...
if i may theorize: one of these two terms is generally recognised by the broader english speaking community
Lol, sure.

I just made sure I did my homework so I can operate with anyone.

And it was huge. I have few worries.
Allow me a small observation: people is not in office or WFH for pleasure, well, at least in most case, but because they need to work, even most talented who in general like they jobs have to accept many not so pleasant aspects of them.

This to say a thing: it's not viable stating "allow those who want the office or WFH individually decide", it's simply too costly for a company, that's why office spaces are often crowded, because being larger cost much more.

So, if a company decide to go remote it MUST go remote PERIOD, if a company decide to have offices it must use them, there is no point in Zoom-in from the office because some coworkers are at home or abroad.

Long story short it's about time to admit that the need of the office is essentially ended, and for certain activities where it's still a thing there is no hybrid option. Companies mandating RTOs prove only to pursue external interests maybe of some inside the company against the interest of the company itself.
Yes, but the problem is that the spec is such that preemptive blocking doesn't need to be implemented.

That means that Java programmers have to be very careful when writing code, lest they block the entire underlying (OS) thread!

Again, Go already went through that experience. It was painful. Java should have learned and implemented it from the start
>the name of the component

Falcon?
Use Notion. It can't get worse.
The old saying is "pay peanuts, get monkeys".

Let me propose a variant of that: "you'll end up with monkeys if you require people to do monkey tricks".
This is a symptom of a broader narrative perpetuated the company itself, that any criticism is from "haters".
Your take-home exam will not get many high quality candidates. Most people who have an option will not put up with this kind of requests.
You can always use X11. /s
if your watch can call

https://www.uber.com/au/en/ride/call-to-ride/

https://support.apple.com/guide/watch/make-phone-calls-apdc3...
That's interesting, because I don't that anyone really has reported these side effects and I don't believe there are any known pharmacological effects from psilocybin or psilocin that would cause any of that.

Were they dried mushrooms you ate? Do you trust the provenance of them? If they were a chocolate bar or similar, many of those do not actually have psilocybin or psilocin in them, and are instead using a variety of different research chemicals that are significantly less understood. If it was dried mushrooms, there are a variety of species that induce hallucinogenic effects through other chemicals than what you find in your usual magic mushrooms.

They might have been regular shrooms, of course - people react to things differently - but that's a different enough outcome that I wonder if it wasn't something else entirely.
If you need to be explicit about thread contexts because you're using a thread that's bound to some other runtime (say, a GL Context) or you simply want to use a single thread for synchronization like is common in UI programming with a Main/UI Thread, async/await does quite well. The async/await sugar ends up being a better devx than thread locking and implicit threading just doesn't cut it.

In Java they're working on a structured concurrency library to bridge this gap, but IMO, it'll end up looking like async/await with all its ups and downs but with less sugar.
> after really grokking topological sort I used it countless times for fairly mundane problems like creating plots.

I'm interested in learning more - in what scenario was topological sorting essential for generating plots, and what specific problem did it solve?
Toddle wants to 'change how we build software' with a visual web app builder
librasteve at furnival.net
100%. I do this all the time, this will be very useful internally.
The best thing about an iPod was most certainly not the wired headphones, it was how much music you could store compared to most preceding devices.
It's actually surprisingly hard to get on some IRC networks these days. A lot of e.g. EFNet servers have pretty narrow I-lines, and it's not always easy even to get a server list unless you're already on.

I like IRC for the culture, mostly. The way people use chat products seem to be pretty shaped by very small product decisions nobody probably thought much about when they were made (e.g. default notification settings), plus whoever happened to be early adopters. But of course, it's never going to have a resurgence.
PrivacyLens Camera turns people into stick figures to preserve privacy
The "badness" of that number depends on the base rate. The base is getting to regulatory approval by doing exploratory studies on humans tissue (you can't ethically do exploratory studies on human subjects).

If the base rate is 0.5%, then 5% is an order of magnitude improvement and pretty good. If the base rate is 4%, then 5% is pretty bad.

I would suspect that the base rate is far below 0.5%.
https://archive.ph/hjMuS
Niacin mega-doses have been used for decades to reduce lipids, triglycerides, etc. and yes when you take 1 gram it will causes a painful flushing.

However to simply raise NAD+ levels you can take as little as 100mg
Start a nonprofit to implement this. What you are suggesting is a lot of work, and it requires an institution to complete and maintain.
Ask HN: Performance of Apple Sillicon vs. ThinkPads (Or Other Linux Laptops)
How's the performance, in terms of pure speed (CPU, memory bandwidth) when comparing macOS running in the latest Apple Silicon series vs. running Linux on a comparable (if there's such a thing) laptop like a Carbon X1 or similar?

Would I see significant performance improvements (e.g. compilation speeds) by moving to M3/M4?

Let's say that I do not care about energy efficiency/battery life.
Because they don't create 4k real threads, and can be scheduled on n=CPU Cores OS threads
Github launched with the tag line "social code hosting" in 2008:

https://web.archive.org/web/20081216011059/https://github.co...

Which changed to "social coding" later:

https://web.archive.org/web/20110217073759/https://github.co...

"social coding" eventually moved to the page title, and disappeared from the page itself:

https://web.archive.org/web/20120202143623/https://github.co...

"Social code hosting" and "social coding" are not on the front page anymore, but they definitely kept all the social features.
The profusion of underpowered interfaces is frustrating but I don't see how browsers could

"just use files"

What does this mean? Providing the POSIX filesystem C language APIs with file descriptor numbers, etc? I guess the browser makers could go Cosmopolitan-C style and emulate the Linux filesystem interface on all platforms, but I think you'd find there's still a weird intermediary layer in between your code and the underlying OS filesystem. Even on Linux the browser would have a virtual filesystem to provide sandboxing & quality-of-service governance. On other systems you'd need a virtual filesystem to paper over those differences between operating systems. Windows exists!
Thanks! I wasn’t offended or anything, don’t get the wrong impression.

What strikes me odd is the fact that an AI that checks AI is an issue. Because AI can mean a lot of things - from a encoder architecture, a neural network, or a simple regression function. And at the end of the day, similar to what you said - there was a human building and fine tuning that AI.

Anyway, this feels more of a philosophical question than an engineering one.
Community Rallies to Save a Car-Free Street (2023)
Stop Offering Me Amazon Gift Cards
I think it's X11 stuff that is using Vulkan for rendering that is still flickering in 555. This probably affects pretty much all of Proton / Wine gaming.
Why do you say that? developing Awk was no less of an accomplishment than C.
> faster

Check out {send,recv}mmsg before something io_uring-ish imho. One syscall/ctxt, many packets.
I use a Raspberry Pi to run a Tailscale subnet router on the LAN. I installed some cheap IP cams but blocked all Internet access so they can only access my LAN. With the Tailscale subnet router I can still get remote access to the camera streams from my phone.
I forgot to add, some have higher genetic predisposition for an autoimmune disorder, and diet/environment/lifestyle can switch those gene sections on.
> I'm talking about predictors of wealth for a new person.

That's almost a tautology then. If you only know one thing about someone, that's also necessarily the best predictor for anything about them. However, it doesn't tell us much about whether wealth does concentrate over time.

> Really.... ? Why?

Because regimes change all the time despite rulers being alive. The death of a ruler by old age rarely triggers regime change, they just get succeeded by someone else. It's usually another event that triggers regime change (peaceful and violent revolutions, war, etc.). Immortal rulers wouldn't be immune to those events.
I would guess the key here is the "researchers reported that they had developed a drone they're calling the CoulombFly, which is capable of self-powered hovering for as long as the Sun is shining."

It only seems to operate off the solar power, no additional power. So the light keeps shining, the drone keeps flying.
He’s the closest man to C still alive. Yet it’s not really “his” accomplishment. C was created by Ritchie alone, Kernighan only wrote the book.
I mean, what exactly do you need innovated? I have a bunch of these cheap cameras (firewalled to only be accessible via LAN of course) that are nearly 6 years old now. They stream 2K video reliably, my DVR records for me, they have excellent quality night-vision via infrared, and I can access them via VPN. What's to improve here?
Yeah, this is super interesting. The obvious follow up for me is what implication this desynchronization has on cognition. People who have done a lot of psilocybin tend to be quite a bit 'different' at least in my experience—they tend to be more reserved, maybe a bit more thoughtful, slower, introspective, etc.

But what causes this change in personality? People who have done a lot of psilocybin seem to be a lot less worried, a lot less neurotic, and a lot less wrapped up in the ego than those who haven't. After all, who wants to be wrapped up and ruminating based on the content of their thoughts? I've always thought of this behavior by those who have used psilocybin to be a feature, not a bug—as if they're enlightened.

But if, say, this newfound personality is the result of a loss in functional connectivity—what does that tell us about how other markers of cognitive function have changed? Is strong FC a prerequisite for strong executive function or other measures of intelligence? The paper seems to suggest that the changes in FC are associated with the default mode network and maybe not other states of brain focus.

But will a macro dose of psilocybin, say—make someone better at their job? Maybe we don't know yet, and maybe there won't be a clear answer; there is a lot of heterogeneity in the way people think, and how they exploit their own cognitive abilities to provide value in the world—so maybe a loss in FC will mean different things to different individauls. But given the suggestion from this paper that the effects of psilocybin may be somewhat permanent, the answer to this question will be a very useful for those looking to benefit from this therapeutic.
Wow! Great disclosure! I find it hard to read though, since the text doesn't properly capitalize the start of sentences. Messes up with the natural language parser I have in my head :)
Convince literally everyone you have ever spoken to, regardless of opinions or political affiliations, that they should vote.

A hundred million Americans have this insane idea that voting doesn't matter, or doesn't change things, or they don't like their options enough, as if that means somehow one of the two options won't end up in charge in a couple months.

The point of voting is not to get your personal favorite personality at the highest office. The point of voting is to take a poll that explicitly influences the direction your organization goes.

Advocate aggressively for things like ranked choice voting and voting holidays to ensure typically poor, underpriviledged people have no more excuses to not vote.
Much agree, and one of the reasons to try to make hacking and fun
practical stuff part of a course is that the knowledge is
stickier. You'll remember the Moog filter you built on a breadboard
which made weird noises after you calculated the RC values wrong.
Maybe not so much the perfect stopband you got a solver to make for
you in a DSP simulator. Feynmann was all about that teaching
realism. Also it takes about 6 months to a year of tinkering to really
get "the pleasure of deeply understanding a topic".

Many uni departments scrapped the electronics labs because it's all a
bit messy, expensive and time consuming and I think the demand for
people who teach it is getting smaller, at least here in UK. Last time
I was asked to give an electronics class it was mainly digital
switching of loads and hooking up I2C sensors. Still we had fun. That
"just get the certificate" mentally of education doesn't leave much
room for the play factor.
It addresses the issue of incentives by trying to create a counter balance to one sided economic forces. It appears as if using tariffs to equalize trade when there is a major surplus imbalance is one of those levers.
Crime is up in your neighborhood, says company that sells burglar alarms.
Second SLS core stage ready to ship to Florida – SpaceNews
Lithium in American Eggs
Google and Apple should put an end to it. Not only does it create a mess for authentication across sites, it also deceptively modifies and tracks interactions outside of an app's boundaries, sending that activity back to app makers that should not be permitted for privacy and security issues alone, much less ethical ones. If there is already a browser on the device, that instance should override all in-app browsers... Even the configuration option is buried deep in config menus.

Almost seems as if it's collaboratively colluded to allow the browser experience to be disjointed, especially in social media apps.
> my impression is that cows as a species will go extinct if not domesticated.

Is that bad? Cows aren't necessary for the food chain and them not existing won't do anything to harm the environment, it will do the exact opposite.

The "cow species" isn't a sentient being who cares whether or not it exists, so if we can reduce the suffering of individual cows who are already here and the outcome is that domesticated cows go extinct, I don't see that as being bad.

It is bad for the dairy farmer, but it's worse for the individual cows and the environment if we keep things the way they are.

Even free-range cows are sent to get fattened up on corn that they can't properly digest before they're slaughtered. Despite what Temple Grandin tried to do, cows are still very stressed and scared before they're slaughtered, and the slaughter process is optimized for speed, so the bolt gun doesn't always stun the cow before they're bled out.

I think it would be hard to look at what we do to end a cow's life at just a fraction of it's natural length and think that it's better than allowing domestic cows to go extinct.
For spacecraft parts, they absolutely don't mind (they're charging for the privilege of course). For the parts I'm familiar with, we generally buy both the necessary flight-rated components (both enough to build the vehicle and some number of spares) and a number of unrated components used in various test apparatuses in a single order. Once you get down to the level of stuff that's not even a flight-test fixture, we can indeed source parts from pretty much wherever. The biggest issue then become US government procurement rules that require us to buy American, but I'm pretty sure I've seen at least Mouser get used before.
> Do you have a reference

She is quoted saying she no longer wishes "to be related to [her] biological father in any way, shape or form" [1]. Musk has publicly ranted about the estrangement, which isn't usually how one mends ties with family [2]. While I have no personal insight into the situation, it's fair to say Musk hates the estrangement and that his child, at the very least, wants nothing to do with him.

[1] https://www.nbcnews.com/news/us-news/elon-musks-child-seeks-...

[2] https://www.mercurynews.com/2022/10/10/elon-musk-says-he-los...
Mermaid is a bit more limited.
What about the screenshot supports the claim it's vaporware?

And in what way do the tolerances not make sense? Just from your vibe check? We don't know anything about what tolerances are being used/held on any of the parts involved with the product, so this doesn't even make sense as a thing to talk about?

Here's the video you're asking for: https://x.com/thetinypod/status/1813589903722311784
I'd look at it the other way: Other high-difficulty jobs have mandatory licenses and certifications that weed out the chaff. Lawyers have the Bar exam, engineers have the Professional Engineering exam, doctors don't have a specific test but they have all of med school, EMTs need to get an EMS license/certification. Software engineers can get their foot in the door with a javascript coding bootcamp.
I don't care?
Saw the pictures of the animals and thought, 'hope the pictures of the herbs are better than the animals' and then read below "The botanical imprecision of the 160 pictures, in any case, would have made identification of particular plants in nature difficult."

Doesn't seem like the book would have been real useful.
I agree, they can already be mentally uncomfortable if you don't like enclosed spaces. Perhaps there's some kind of psychotherapeutic techniques used prior to getting in the MRI during the come up period, to kind of boost positive emotion about the whole process.
> it's the kind of languages that you can pick up in 1 afternoon

Yeah nah. Especially not for current Python, which is quite a bit more complex and involved than it was 20 years ago.

Of course you can get some stuff done in Python on your first afternoon, but that's true for most mainstream languages. And that's nowhere near the same as actually knowing what you're doing.
They should have used an LLM to write responses when nobody's at the office
Not quite - it moves some logic to the GSP firmware, but the user-space driver is still a significant portion of code.

The exciting bits there is the work on NVK.
Please don't give it to politicians, they are just going to funnel it to themselves.
Here's a setup that works. Get POE cameras. Get a powered switch with sufficient power to power the cameras. The cameras and the switch form their own subnet. Get a PC with two Ethernet jacks (or an Ethernet and a WIFI). Install NVR software, Blue Iris, iSpy, ZoneMinder, etc, on the PC to record and process the videos from the cameras. These softwares are all good with RTSP and ONVIF, with easy camera detection via port scanning. Connect the PC to the switch on one Ehternet jack and connect it to your general network with the other one (or WIFI). The cameras are running in their little isolated subnet. The NVR PC sits between the camera subnet and the general subnet. Access from outside reaches the NVR PC only, not the cameras. You can even open the WAN firewall to reach the PC's WIFI side to access the videos from Internet. Some of these NVR software can stream videos to outside phone apps or web apps.
> if your kids don't trust you then fixing that should be your first priority before you start pointing fingers everywhere but inward

While the present state of Musk and his daughter's relationship is detestable, I don't think we can conclude they didn't try--in private--to mend the relationship before she concluded it was a lost cause.
Would be great if you could narrow down to sub-genres. Music is not like apps where you can just post a general list in the home page. Can't expect someone that likes hip hop to like experimental. Maybe also get inspiration from Product Hunt's ability to have sub categories.
My Take on a Chinese Macro Keyboard
They dont control anything. If they left the network would readjust difficulty after 10 minutes and continue on the same way.

Seriously educate yourself. You're being the guy in the op comment.
The UK has found that the institutions were harming children more than parents though.
Httpwtf? (2021)
okay so explain our short telomeres promoting cancer

what are armchair archeologists going to say, “thats because it enabled strong community ties and the humans with long telomeres didn't value life as strongly” as opposed to being a total freak accident that had nothing to do with anything
I have a pro max and even with this size some websites are cramped and badly designed. I can’t imagine with a mini version… such a shame because it’s really nice to have a small phone at all time
5% is decent? The index made about 10% on average, Peter Lynch about 30%, and Buffett in the ‘60s was at 40-50%.