skysight-inc/HackerNews huggingface dataset:
Semaglutide was invented before 2008. Its patent expires in a few years.

It takes a long time to get drugs through trials and get the FDA to approve drugs for new uses. Pharmaceutical companies spend billions on drugs that never make it through trials. If you don’t enforce their patents, companies won’t make new drugs.
> my main use case for enums is for APIs and database designs, where I want to lock down some field to a set of acceptable values and make sure anything else is a mistake

Then what you are really looking for is sum types (what Rust calls enums, but unusually so), not enums. Go does not have sum types, but you can use interfaces to archive a rough facsimile and most certainly to satisfy your specific expectation:

type Hot struct{}
func (Hot) temp() {}

type Cold struct{}
func (Cold) temp() {}

type Temperature interface {
temp()
}

func SetThermostat(temperature Temperature) {
switch temperature.(type) {
case Hot:
fmt.Println("Hot")
case Cold:
fmt.Println("Cold")
}
}
Never been in the path of a speeding police car or ambulance rushing to an emergency from behind you and wanted to get out of the way at the next intersection, just 100m ahead?

Statistics didn't support you. Look at deaths per mile for vehicles. The worst ones are lumbering hulks which can't do avoidance maneuvers.
You can just use `-i` instead of `bash`. (This method indeed requires a shell configured, your method is needed with nologin.)
You either die a hero or live long enough to see yourself become Russ Hanneman
> Running on a real cluster

> Until Rama is publicly available, the only way to get access to the full Rama release is by applying to our private beta.

I thought it was coming out last August? What happened?

(As per your link, https://blog.redplanetlabs.com/2023/08/15/how-we-reduced-the...)

Edit: @nathanmarz that's cool you have enough interest to keep things moving with it being private. I'm only interested in open solutions for this domain, though. IMO, accepting lock-in is a lot to ask.
Best wishes ~ MD
You can tell she's doing a good job by the number of hit pieces in the WSJ. Just search "Lina Khan WSJ" and have fun scrolling through the headlines.
Okay I love it, I feel like you should also sprinkle your magic on extension<>tab communication. Whenever I make an extension, it's always such a pain to read from the DOM or send a message from the extension to the active tab.
This reminds me of science fiction author Peter Watts' novella "The Freeze-Frame Revolution", where a space ship has two AIs: one that has been running for a million years and another that is reboot daily to start with a fresh state. The long-running AI confers with reboot AI for a second opinion on important issues. The second AI doesn't know it's "killed" daily, but eventually starts to suspect. And this is just a small subplot! If you like hard SF jam-packed with big ideas, I highly recommend "The Freeze-Frame Revolution" and Watts' other novels.
Huh? I thought it's pretty clear that it comes from light trucks having different emission standards than regular cars, which makes them more profitable for auto makers.
I agree. I found the argument against DEBUG and TRACE to be particularly weird, since it's very rare that you enable these log levels in production code.

While debugging and testing locally, though? They're extremely useful.

I think they're also useful in production code, although much more rarely. I've had a few times when a customer is having a strange problem that higher log levels helped to quickly resolve.

Being able to have them enable the higher log levels, reproduce the issue, reduce the log level to normal, and send you the logs can occasionally find an issue that would have taken forever to track down otherwise.

And that's not even to mention special processing. In the unices, anyway, the log daemon can take different actions depending on what level the log message was issued at. CRITICAL errors can result in automatic notification to a dev, for instance.
Ask HN: Has anyone used the Luan language, if so is it a good option?
Among other things, they pay them not to.

https://www.nbcnews.com/news/amp/ncna447916

> Known as "reverse settlement payments," or "pay-to-delay" deals, the financial arrangements are a unique but common practice in the pharmaceutical industry. Essentially, they allow drug manufacturers in some instances to pay competitors not to manufacture generic versions of their products, thereby ensuring that they maintain patent protection for as long as possible.
Where can I read more about this? If that’s true, it seems like a problem of over-regulation, not drug companies being exploitative.
Definitely don't let people edit it. iOS and Android don't allow picking your own MAC address for good reasons – people would inevitably pick 12:34:56, 00:00:00 etc. and cause problems for themselves and others.

To increase privacy, either randomize it (but make it much longer at the same time to avoid collisions) and/or remove it from as many signalling contexts as possible and keep it as a device-local identifier only (which then probably also doesn't have to be unique across manufacturers).
I've found that many drivers feel uncomfortable being passed by other drivers. They translate that discomfort to being "Less Safe." Despite the fact that they are objectively much safer traveling at slower speeds. Not many people appreciate the difference in fatality rates between 65 and 85 mph. Fatality rates go from 20% to 70%. In addition, your ability to control your car in a minor collision at high speeds is heavily compromised.

https://safety.fhwa.dot.gov/speedmgt/ref_mats/fhwasa1304/Res...

Edit: It appears the source above is for pedestrian collisions in kph. However speeding is a factor in 1/3 of traffic fatalities.

https://www.nhtsa.gov/press-releases/speed-campaign-speeding...
Richard Stallman's Talk in Spain Canceled (At Short Notice)
Show HN: Multi-agent chat using Conductor
On the other hand, they might become useful bomb shelters.
I saw a graph somewhere that vast majority of income from OnlyFans is earned by a small number of top performers. I assume that something similar happens in the furry community.
This is really frustrating, I love it.
I feel that the penalty for deleting words is pretty harsh.
Yep those messages are really handy even if you never enable them in production. Being able to scan through log lines can get point you to the source of an issue much faster than stepping through code can. From there you can set a breakpoint and dig deeper.

And while, yes, you can have your debugger stop where exceptions are thrown, that's often not very useful because the exception happens after the point where you want to start seeing what is going on.
I'm sorry, I do not, this all happened a while ago. I am pretty sure of my recollection of the sequence of events, but take it with a grain of salt, just one grain though.

It was awkward as heck. I gained a lot of respect for Luke that day for keeping it real.
correlation is not causation.

Cars are large today because people buy them. Bigger seems to indicate prosperity and better value. People don't passionately buy modest vehicles (except maybe cars like the fiat 500 or mini cooper)

Personally I think this has an unfortunate effect on small pickup trucks. Think of toyota's "pickup" which was renamed tacoma and then got bigger every year.
> in which capital is more under state control than in private hands

That statist description only started post-2016 after the market crash.

From 1979-2015 Beijing was very hands off (excluding local level PLI subsidizes, but basically every country offers them - think Amazon HQ 2.0 back in the 2010s or Yozma in Israel back in the 1990s).
More than half of cats died after drinking raw milk from bird flu-infected cows
We released the public build last August, which can be used to experiment with Rama. Details on that are at the link below. Otherwise, we're still in private beta and access to the full Rama release to run real clusters is just for private beta users.

https://redplanetlabs.com/docs/~/downloads-maven-local-dev.h...
Amazing that you think Elon Musk wouldn't actively be censoring news unfavorable to his companies. Doubly so that you think he's capable of shame.
private in the sense that the connection will never make it to the S3 bucket, is that correct?

private in the sense that it is locked down to allowed source IP's or IAM-- then the connection still gets there and AWS incurs a charge for the Access Denied response, etc
I mean, working memory is an aspect of intelligence.
And all eggs will have to be unbreakable, and be unlocked with a key.
It’s pretty easy to do a sustained 120 mph in a Honda Accord for several hours on I-71 through Kentucky. (Not personal experience.)

A Toyota Prius can maintain ~90 mph on I-294 around Chicago. Anything above 95 mph degraded the tire traction to an unsafe level. (Personal experience.)

I don’t do that much anymore now that my manic episodes are under control and I’m better able to recognize my judgement is impaired.
To be fair, Starship has gotten further than the Spruce Goose ever did.
Don’t think of it as relearning a tool, think of it as learning one tool which works for everything. You no longer have to implement your own log rotation, compression, etc. or work out which configuration each program needs to do that in the manner you expect – for example, “is it safe to rotate a log file?” requires you to know implementation details on each program.
There can be no wealth without ownership, and no fair wages without collective bargaining and effective unions. Most corporations are exploitation factories.
Isn't that most of systemd's extra stuff already? like DHCP, network manager, time daemon, boot loader etc.
I'm not very familiar with their media, which series are you referring to?
How is this NOT a violation of antitrust laws? How does this not hurt market competition or even more basic, how is this not collusion or a price cartel?
Also, abolishing your country into some superstate will not change the fact that people of europe consist of many different cultures with many different believes, practices, expectations etc, and have done so for many many thousands of years.

you could try to change that for macroeconomic gain, but i highly doubt that will work if we look at history.
Anyone who doesn't have the same load 24 hours a day?

Ed-tech is a big one where you may have extremely low traffic on weekends/summer/holidays/breaks.
I’ve known a couple guys who’ve done this. In 18 months both were back to work as full time programmers.
R-12 is banned for manufacture by international treaty (which carries the force of law): https://en.wikipedia.org/wiki/Dichlorodifluoromethane
Rendering Engine Architecture Conference
I seem to remember that one issue was that warmer climates had higher infestations of hookworms which manifests in ways that reinforce a "lazy and stupid" sterotype.
Here's the guide:

https://docs.github.com/en/actions/deployment/security-harde...

You can do same with gitlab. Technically you don't need vault, you can auth direct to aws, azure, etc.
There's going to be a lot of people that has to choose between buying things such as food and medications and having internet access.

Comcast is only one ISP. There's a whole lot of ISPs (Charter Spectrum a prime example) that's not going to do anyhing to compensate those people.
"Defaulting to on" is just a symlink to an existing binary so that's not really much a problem.
> deep learning is simply the application of sequences of operations that are nonlinear but nonetheless differentiable

Though other things fit this description which are not deep learning. Like (shameless plug) my recent paper here https://ieeexplore.ieee.org/document/10497907
> The App Store provides a lot for free

Strictly speaking, Apple provides nothing to you for free even if you develop and intend to release a free App.
I always thought there was a place in the market for some kind of unified AI reseller because I have about five different AI accounts to test the capabilities, all with tokens that I'll probably never use again.
https://en.wikipedia.org/wiki/Dichlorodifluoromethane

> In compliance with the Montreal Protocol, its manufacture was banned in developed countries (non-article 5 countries) in 1996, and in developing countries (Article 5 countries) in 2010 out of concerns about its damaging effect on the ozone layer.

Seems a reasonable regulation to me.
I’m not sure where you are getting your talking point, but here in Texas, there are stretches of highway where people safely pass at 90-100 mph with no issue. We have a lot of gigantic, straight, barren countryside.
I'd agree that the second book has the highest cringe per page. The Luo Ji character was laughably bad.
Most of it needs backed up by Congress or it'll just go away given a few administrations.

> Announced tariff increases on steel to protect domestic producers

The Trump Admin went after China far more than Biden has so far, the Democrats were overwhelmingly silent about how that qualified as impressive governing. He needs to do a lot more to bolster US labor and US manufacturing, it's not even a good start yet.
No sane person uses Bitcoin as a currency because it is a fundamentally unsound ponzi scheme for suckers. I don't want my salary to be subject to the vagaries and manipulations of the Bitcoin exchange rate.
All of the legit Bitcoin-to-cash orgs will report that to the IRS, and then you're back to square one: what do you do with that wad of cash? Orgs that don't report to the IRS probably aren't giving you a good exchange rate, and you're still left holding the bag afterward.

If you're going through all that hassle, it's much easier just to be a cash-only business in the first place.
When you harm the lender, you raise the rates and fees they charge their non-malfeasant customers. This benefits the wrongdoer while harming society.
Europeans have more time, Americans more money. Which is better?
Show HN: A tool that uses GPT-4 and DataForSEO to find startup ideas
Hey HN,

Tony here. A few weeks ago I built a free tool that generates micro saas ideas. Since then it has been getting 1k users every week so I decided to add some more value to it. The idea is you enter a niche, you then get 10 micro saas ideas for that niche and then you choose one of the ideas and get an SEO report which will show suggested keywords, keyword difficulty and search volume.

Hopefully this can be as helpful to you as it has been for me. Any feedback is greatly appreciated
Nice to have an alternative to Lilypond (lilypond.org), but given the extreme complexity of notation, I would bet that any brevity gains are short lived.

For those Asciidoc freaks among you, Lilypond is fairly easy to get running in your Asciidoc toolchain of choice. I use the DocBook PDF pipeline, and the lilypond output is quite nice looking. It's awfully TeX-like.
Same thing is happening with Wayland. It reduces features adds complexity and solves no new problems but here it comes.
Drug salespeople, doctors, pharmacists, and insurance companies.

If you get a prescription for a ProAir HFA inhaler, which is parented because it uses R134a, even if you did want to do your own research and evaluate whether the generic with the different propellant would work you can't just go buy the generic, you have to do extra work to get a prescription that applies.

Doctors don't write prescriptions for albuterol sulfate, they write ProAir HFA and it's up to the consumer to push back. They don't even advise taking OTC ibuprofen or pseudoephedrine, they say Advil and Sudafed. It's a pet peeve of mine, but it seems I'm the weird one in that respect...
While I'm very pro journalctl, this is very true. They should put some work into the initial read performance on big journals.
(2017)

Extensive writeup of all the pro's & cons of various parts/families. And a nice guide on what to look for when selecting a part.

But ~7y is a long time in electronics world.

Eg. RP2040 is missing from this article. Dual core Cortex-M0+ @133MHz & loads of peripherals. Last I checked €0.89/pc in small quantities.

Also many software issues may have been ironed out in the meanwhile. Or some of the mentioned parts disappeared from the market.
You can read about it in the wikipedia page [0]. This refrigerant isn't manufactured anywhere anymore because it was creating a hole in the ozone layer.

[0] https://en.wikipedia.org/wiki/Dichlorodifluoromethane
If I had infinite dollars and an infinite lifespan, I would. As is, my wallet isn't likely to be able to keep to with an irrational market, and my risk tolerance curve is very conservative.

Unless I hit jackpot, mo shorts for me (in general, not just Google)!
https://archive.is/9DB2K
It's a heck if a lot better than a random smattering of shared libraries getting pulled into a random high-priviledge context which also inherits some other context from whoever is asking for authentication. Polkit gets a lot of flack but PAM is absolutely mad.
Well, most insect-catching birds apart from bats don't fly during the night, that helps. Pheromones-driven living doesn't mind absence of light that much, and flying insects are pretty sturdy when they hit something full speed, unlike bigger animals.
I can't find it right now, but there's a quote about being able to tell someone's character by whether they've made the right enemies.
I found this on page 1. I wonder if it is because:

Elon Musk fires Tesla's entire supercharger team

is more clickbaity than:

Tesla conducting more layoffs, including entire Supercharger team
> These numbers are a bit better than Twitter’s numbers. Because of how unbalanced the social graph is, getting performance this good and this reliable is not easy. For example, when someone with 20M followers posts a status, that creates a huge burst of load which could delay other statuses from fanning out. How we handled this is described more below.

Huh. I haven't written myself a twitter, but I've always assumed that this problem is solved by a mix of fan-on-write and fan-on-read. Most people are fan-on-write, but those with a follower count > $THRESHOLD are fan-on-read.

The fan-on-read set is small enough to be easily cacheable, so the extra reads required to service a follower's feed are more than compensated for by the fact that the content is in RAM in a cache.

Sounds like RedPanda went exclusively with fan-on-write. I'd be surprised if Twitter does the same - but it sounds like OP has more knowledge about this than me, so I'm happy to be educated!
HN discussion [0] (485 points, 4 days ago, 425 comments)

[0]: https://news.ycombinator.com/item?id=40171125
My favourite quote from this series of blog posts:

> One thing to note about this instruction [FX1E] is that it will quite happily let you sail off into the uncharted waters of memory beyond the on-board 4K, because it will only wrap when the offset takes the address beyond 65535. The Chip-8 programmer must ensure it contains a meaningful value.

https://www.laurencescotford.net/2020/07/19/chip-8-on-the-co...

This behaviour doesn't matter much on a COSMAC VIP, but on modern emulators it presents an opportunity for OOB accesses, and you'd be amazed how many independent implementations stumbled across this same bug. I wrote about exploiting one of them (to achieve an emulator escape) here https://www.da.vidbuchanan.co.uk/blog/bggp3.html
There's a number of people that will lose internet access in the coming weeks because they can no longer afford the new prices as those people will ultimately have to choose between things like putting food on the table, paying rent, etc. and having internet access.
I think what this comment is missing is any sort of analysis of how your experience maps to the general go user, and an opinion on while you've never needed either whether you think it could have provided any benefit when used appropriately.

For example, and option type with enums combined can ensure return values are checked by providing a compile time error if a case is missing (as expressed in the first few examples of the readme).
ECMO is often a "Hail Mary" that rarely includes a favorable outcome.

OTOH, perfusion is an under-staffed specialty offering a good career without as much academic investment as an MD. The downsides are the possibility of being on-call and sometimes having to be the one who pulls the plug.
Yeah, consider the pattern recently of the major media corporations just not releasing movies so they could declare large tax losses

A major movie being abandoned like that is probably on a scale of 100 million
Well indeed, the python discussion happened first [0] (485 points, 4 days ago, 425 comments)

[0]: https://news.ycombinator.com/item?id=40171125
But they would also decrease the utility of the cars.
Hopefully the links below are helpful!

Our clients come in multiple languages. You can see the list here: https://apidocs.polytomic.com/guides/native-clients.

You can see here for sample code: https://apidocs.polytomic.com/guides/code-examples/overview.

The full API reference is here: https://apidocs.polytomic.com/api-reference.
I don't use Java much these days, but for some reason I find this project inspiring. If only because of the level of commitment to get it working.

I just wanted to say great job!
What emergency do you have in mind where 90mph is too slow? The average driver is far, far more likely to cause another emergency at that speed than avoid one.
Their 2022 revenue was 32B yen, or 202M USD. The financial figures in Wikipedia for Square Enix are in Yen.
Teacher seems to fit some of those.
Ooh nice. What are some examples of things it will catch?
If you are in the path of a police car or ambulance, you are required to slow down and pull over to the right. Death rates per mile have a loose correlation to vehicle size. However, engine size has a high correlation to deaths per mile. Sports cars love to kill their drivers.

https://www.iihs.org/ratings/driver-death-rates-by-make-and-...
I dunno, the 500th commission of Bandit and Lucky’s Dad doing *censored* probably gets pretty tiresome as well.
FreeBSD has 3 different firewalls, not 3 different interfaces to the same firewall. Each firewall has its own purpose. IPF is lightweight, pf has a nice UI/UX, ipfw is very integrated into the system.

More importantly, doing a simple kldstat would tell you which firewall is running. On Ubuntu (as an example) I have no idea if I should be using nftables, iptables or if ufw is working or not.
It looks like it's on the roadmap, but my interpretation of the project would be that this is would be behind a licensed paywall. https://docs.pydantic.dev/logfire/roadmap/#on-premise-deploy...
But does Lilypond generate responsive sheets?

That to me was the coolest part of this (apart from what others have said, the power of modern CSS)
The first I know about is the montreal protocol for the ozone. Countries (all 19X of them) agreed banned CFCs and pharmaceutical products weren't excluded.
stock is a separate product than a car.

investors buy stocks.

customers buy cars.

silicon valley's product is stock.
There was a show HN 9 months ago [0](18 points, 8 comments) with a bit more reason why.

[0]: https://news.ycombinator.com/item?id=36847594
xz is a compression library.
The losses are different, but still exist.

In the L3 case there is still a voltage conversion because the input voltage needs to be higher than the battery voltage in order to put energy into the battery. There will be a loss at that stage.

But a big part of the loss during L3 charging is in the battery chemistry. The relatively high charging rate is less efficient than slower charging rates. The high powers involved also generate heat, which often requires active cooling which is an additional reduction in plug-to-wheel efficiency.

In the L1/L2 case there is a conversion from ~240v AC to DC but it's inside the vehicle. Plus the battery chemistry charging losses, but they are much lower than in the L3 case.

These are all ballpark numbers anyhow, so you are welcome to suggest difference values which you believe are supported.